LOCUS       DAFLWQ010000001        96944 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.001, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000001 DAFLWQ010000000
VERSION     DAFLWQ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 96944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 96944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..96944
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.001"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(59..187)
                     /locus_tag="L1V16_000001"
     CDS             complement(59..187)
                     /locus_tag="L1V16_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBN1274376.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="L1V16_000002"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="L1V16_000002"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBN1274377.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="L1V16_000003"
     CDS             complement(1674..2729)
                     /locus_tag="L1V16_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBN1274378.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="L1V16_000004"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="L1V16_000004"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HBN1274379.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="L1V16_000005"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="L1V16_000005"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HBN1274380.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="L1V16_000006"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="L1V16_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HBN1274381.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="L1V16_000007"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="L1V16_000007"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBN1274382.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="L1V16_000008"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="L1V16_000008"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HBN1274383.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="L1V16_000009"
     CDS             10491..12050
                     /locus_tag="L1V16_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HBN1274384.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="L1V16_000010"
     CDS             complement(12161..14092)
                     /locus_tag="L1V16_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1274385.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="L1V16_000011"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="L1V16_000011"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBN1274386.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="L1V16_000012"
     CDS             complement(15021..15773)
                     /locus_tag="L1V16_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1274387.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="L1V16_000013"
     CDS             complement(15932..16141)
                     /locus_tag="L1V16_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274388.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="L1V16_000014"
     CDS             complement(16152..17480)
                     /locus_tag="L1V16_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274389.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            17616..17771
                     /locus_tag="L1V16_000015"
     CDS             17616..17771
                     /locus_tag="L1V16_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274390.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(17845..18432)
                     /locus_tag="L1V16_000016"
     CDS             complement(17845..18432)
                     /locus_tag="L1V16_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBN1274391.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="L1V16_000017"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="L1V16_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBN1274392.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /locus_tag="L1V16_000018"
     CDS             complement(20012..21301)
                     /locus_tag="L1V16_000018"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBN1274393.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="L1V16_000019"
     CDS             complement(21455..22387)
                     /locus_tag="L1V16_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274394.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="L1V16_000020"
     CDS             complement(22544..23203)
                     /locus_tag="L1V16_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBN1274395.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="L1V16_000021"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="L1V16_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBN1274396.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGASGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="L1V16_000022"
     CDS             complement(24244..24534)
                     /locus_tag="L1V16_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274397.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="L1V16_000023"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="L1V16_000023"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBN1274398.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /locus_tag="L1V16_000024"
     CDS             complement(26821..28176)
                     /locus_tag="L1V16_000024"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBN1274399.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="L1V16_000025"
     CDS             complement(28200..29369)
                     /locus_tag="L1V16_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274400.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /locus_tag="L1V16_000026"
     CDS             complement(29366..30253)
                     /locus_tag="L1V16_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBN1274401.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="L1V16_000027"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="L1V16_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBN1274402.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="L1V16_000028"
     CDS             34320..34841
                     /locus_tag="L1V16_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBN1274403.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="L1V16_000029"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="L1V16_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="L1V16_000030"
     CDS             complement(36284..36940)
                     /locus_tag="L1V16_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274404.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="L1V16_000031"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="L1V16_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBN1274405.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /locus_tag="L1V16_000032"
     CDS             complement(38477..39475)
                     /locus_tag="L1V16_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBN1274406.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="L1V16_000033"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="L1V16_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBN1274407.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="L1V16_000034"
     CDS             complement(40491..41222)
                     /locus_tag="L1V16_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HBN1274408.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="L1V16_000035"
     CDS             complement(41226..42491)
                     /locus_tag="L1V16_000035"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HBN1274409.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="L1V16_000036"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="L1V16_000036"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBN1274410.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="L1V16_000037"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="L1V16_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBN1274411.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="L1V16_000038"
     CDS             47833..49335
                     /locus_tag="L1V16_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HBN1274412.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="L1V16_000039"
     CDS             49337..50074
                     /locus_tag="L1V16_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBN1274413.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50119..50292)
                     /locus_tag="L1V16_000040"
     CDS             complement(50119..50292)
                     /locus_tag="L1V16_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274414.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            50268..50933
                     /locus_tag="L1V16_000041"
     CDS             50268..50933
                     /locus_tag="L1V16_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1274415.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNEFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            complement(51015..52181)
                     /gene="dnaJ"
                     /locus_tag="L1V16_000042"
     CDS             complement(51015..52181)
                     /gene="dnaJ"
                     /locus_tag="L1V16_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBN1274416.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(52332..54161)
                     /gene="dnaK"
                     /locus_tag="L1V16_000043"
     CDS             complement(52332..54161)
                     /gene="dnaK"
                     /locus_tag="L1V16_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBN1274417.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(54212..54775)
                     /gene="grpE"
                     /locus_tag="L1V16_000044"
     CDS             complement(54212..54775)
                     /gene="grpE"
                     /locus_tag="L1V16_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBN1274418.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54869..55912)
                     /gene="hrcA"
                     /locus_tag="L1V16_000045"
     CDS             complement(54869..55912)
                     /gene="hrcA"
                     /locus_tag="L1V16_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HBN1274419.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(56146..57312)
                     /locus_tag="L1V16_000046"
     CDS             complement(56146..57312)
                     /locus_tag="L1V16_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBN1274420.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNAHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(57328..57555)
                     /locus_tag="L1V16_000047"
     CDS             complement(57328..57555)
                     /locus_tag="L1V16_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBN1274421.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            58039..58629
                     /locus_tag="L1V16_000048"
     CDS             58039..58629
                     /locus_tag="L1V16_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBN1274422.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            58819..59532
                     /locus_tag="L1V16_000049"
     CDS             58819..59532
                     /locus_tag="L1V16_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274423.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(59647..60657)
                     /locus_tag="L1V16_000050"
     CDS             complement(59647..60657)
                     /locus_tag="L1V16_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBN1274424.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(60694..61176)
                     /locus_tag="L1V16_000051"
     CDS             complement(60694..61176)
                     /locus_tag="L1V16_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HBN1274425.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            61326..61694
                     /locus_tag="L1V16_000052"
     CDS             61326..61694
                     /locus_tag="L1V16_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HBN1274426.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            62159..62611
                     /locus_tag="L1V16_000053"
     CDS             62159..62611
                     /locus_tag="L1V16_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1274427.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(62735..63586)
                     /locus_tag="L1V16_000054"
     CDS             complement(62735..63586)
                     /locus_tag="L1V16_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HBN1274428.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(63599..64384)
                     /locus_tag="L1V16_000055"
     CDS             complement(63599..64384)
                     /locus_tag="L1V16_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1274429.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            complement(64736..65677)
                     /gene="ribF"
                     /locus_tag="L1V16_000056"
     CDS             complement(64736..65677)
                     /gene="ribF"
                     /locus_tag="L1V16_000056"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HBN1274430.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            complement(65681..66604)
                     /gene="truB"
                     /locus_tag="L1V16_000057"
     CDS             complement(65681..66604)
                     /gene="truB"
                     /locus_tag="L1V16_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBN1274431.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            complement(66972..69334)
                     /locus_tag="L1V16_000058"
                     /pseudo
     CDS             complement(66972..69334)
                     /locus_tag="L1V16_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            69782..69955
                     /locus_tag="L1V16_000059"
     CDS             69782..69955
                     /locus_tag="L1V16_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1274432.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            complement(70112..70459)
                     /gene="rbfA"
                     /locus_tag="L1V16_000060"
     CDS             complement(70112..70459)
                     /gene="rbfA"
                     /locus_tag="L1V16_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBN1274433.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(70486..72792)
                     /gene="infB"
                     /locus_tag="L1V16_000061"
     CDS             complement(70486..72792)
                     /gene="infB"
                     /locus_tag="L1V16_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBN1274434.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(72805..73116)
                     /locus_tag="L1V16_000062"
     CDS             complement(72805..73116)
                     /locus_tag="L1V16_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HBN1274435.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(73113..73406)
                     /locus_tag="L1V16_000063"
     CDS             complement(73113..73406)
                     /locus_tag="L1V16_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBN1274436.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(73428..74603)
                     /gene="nusA"
                     /locus_tag="L1V16_000064"
     CDS             complement(73428..74603)
                     /gene="nusA"
                     /locus_tag="L1V16_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBN1274437.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(74626..75099)
                     /gene="rimP"
                     /locus_tag="L1V16_000065"
     CDS             complement(74626..75099)
                     /gene="rimP"
                     /locus_tag="L1V16_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBN1274438.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(75244..79602)
                     /locus_tag="L1V16_000066"
     CDS             complement(75244..79602)
                     /locus_tag="L1V16_000066"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBN1274439.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            complement(79814..81523)
                     /locus_tag="L1V16_000067"
     CDS             complement(79814..81523)
                     /locus_tag="L1V16_000067"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBN1274440.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            complement(81591..82859)
                     /gene="rseP"
                     /locus_tag="L1V16_000068"
     CDS             complement(81591..82859)
                     /gene="rseP"
                     /locus_tag="L1V16_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBN1274441.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(83020..83820)
                     /locus_tag="L1V16_000069"
     CDS             complement(83020..83820)
                     /locus_tag="L1V16_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBN1274442.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(83817..84629)
                     /locus_tag="L1V16_000070"
     CDS             complement(83817..84629)
                     /locus_tag="L1V16_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBN1274443.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(84824..85381)
                     /gene="frr"
                     /locus_tag="L1V16_000071"
     CDS             complement(84824..85381)
                     /gene="frr"
                     /locus_tag="L1V16_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBN1274444.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(85384..86106)
                     /locus_tag="L1V16_000072"
     CDS             complement(85384..86106)
                     /locus_tag="L1V16_000072"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBN1274445.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(86242..87123)
                     /locus_tag="L1V16_000073"
     CDS             complement(86242..87123)
                     /locus_tag="L1V16_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBN1274446.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(87222..88004)
                     /gene="rpsB"
                     /locus_tag="L1V16_000074"
     CDS             complement(87222..88004)
                     /gene="rpsB"
                     /locus_tag="L1V16_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBN1274447.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            88363..88842
                     /locus_tag="L1V16_000075"
     CDS             88363..88842
                     /locus_tag="L1V16_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HBN1274448.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            89059..90150
                     /gene="phnW"
                     /locus_tag="L1V16_000076"
     CDS             89059..90150
                     /gene="phnW"
                     /locus_tag="L1V16_000076"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBN1274449.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            90143..90271
                     /locus_tag="L1V16_000077"
     CDS             90143..90271
                     /locus_tag="L1V16_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBN1274450.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            90275..90820
                     /locus_tag="L1V16_000078"
     CDS             90275..90820
                     /locus_tag="L1V16_000078"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBN1274451.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(91274..92965)
                     /locus_tag="L1V16_000079"
     CDS             complement(91274..92965)
                     /locus_tag="L1V16_000079"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBN1274452.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(93385..94332)
                     /gene="arcC"
                     /locus_tag="L1V16_000080"
     CDS             complement(93385..94332)
                     /gene="arcC"
                     /locus_tag="L1V16_000080"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBN1274453.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(94447..95466)
                     /gene="argF"
                     /locus_tag="L1V16_000081"
     CDS             complement(94447..95466)
                     /gene="argF"
                     /locus_tag="L1V16_000081"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBN1274454.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(95557..96786)
                     /gene="arcA"
                     /locus_tag="L1V16_000082"
     CDS             complement(95557..96786)
                     /gene="arcA"
                     /locus_tag="L1V16_000082"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HBN1274455.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT        26626 a        20854 c        16988 g        32476 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagcc cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagccat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgcac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaag tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacga cgtcttgacg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga tttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgctacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gagcctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataatcagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccacacc gaacatactt tcgccacttt tttatcttat
    47701 tatacatgtt atgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg tcatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt atccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac attcttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccaacac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattactgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttctg gtggacaaaa acagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacttct gcactcgatc ctgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atggggttcg ctaaagaagt ggccaatcgc gtcatgttca ttgacgacgg
    49981 aaacttttta gaagatggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc acggtcgcca
    50101 tgaagggacc gtgtattttt atcttcttat tttctcacct aatcgtatca gccgcatcgc
    50161 ttgttttcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg atgatatcaa gtacatagtc gataccaccc tcacttaatt gagcttgatt
    50281 tttcttctcc atattatgta gttgtgggac aactttctga caatcagcaa ttgtgtcaag
    50341 aacggatcaa tcctttattg gagttgctcg aaagggtctt ctcttattac ggacaggctt
    50401 tgctcactgt acatagacaa caaatcatta tcctagtcaa tcggatttcc agagcctcat
    50461 tgctatcatt gcttgataaa atccagacaa agtttaataa aatgtatcag ttacagctaa
    50521 actttggaat tgggtcgctt tgttatacag agcaagagac accgcaatct ttccttcatg
    50581 ccaaacaagt ttgcgaatgg atagctttcc atcaatctgt gaacgagatc cgcttttttg
    50641 aagatttaga cctcgggatc gttttaccag caatcccgtc agatcaacga acattatatg
    50701 taaaacgtat tttgaaaagc ctgacagaag aagaagtaca tttgttcaag aagactttgg
    50761 catgcttcag taaaaataac ggaagcatca aaaattgctc agaagaatta tttattcata
    50821 aaaacacctt gcaatatcga ttgaacgagt tccattctct cactggttat acccctagaa
    50881 actatgacga ttatcatatt ctaaagctgg cttttttgtt ggtacaaaca tgacaactac
    50941 aaaaaaacca ggcgaacata tgattgttcg tctggttttt aattattaat gacttagcgt
    51001 ttttactaga aaaactactt ccgctttttc ccgccaaaag catctttaaa cttatcgaag
    51061 aaaccgtctt cttgctgttc ttcaactttg atgccgccag cttcagcgaa tgcacgtaat
    51121 gcttctcttt gttgttcatt tagatttttc ggtgtgatca gttttacttt gacatgttgg
    51181 tcgcctgttg caccaccacg taacttcgga gcgccttttc cacgtaaacg gaagttcgta
    51241 cctgtctgtg ttccagcagg gatcttcaat ttcacatctc catggacagt tggtacttgg
    51301 acttcatccc ccaaagctgc ttgtacaaaa cttaaaggca attcatagta aatttcagaa
    51361 ccttcacgat caaagatatc actttcttct acacggaaga ccacatacaa atcaccaaat
    51421 ggtccgccgt tttctccagc ttctccttga ccagctaaac gcatttgttg tccttcttct
    51481 acaccagctg gtacattcac tttaactgaa tgtgctttct tctcatgtcc tgagccatga
    51541 caggttggac aaggttcttt gatttctttc cctgtcccat gacaaacatc acaagtttga
    51601 cggctcatca ctcgtccaag tggtgtttgg cgttctacat taatcgtacc tgcaccatga
    51661 catttatgac aagtagttgg ttgtgtgcct ggttttgcac cgttcccacc acaagtatga
    51721 cagatttctt cccgattata cttgatttct ttttctacac caaaaatcgc ttcttcaaaa
    51781 gacaagtcga ccgtatattg caaatcagca ccttgacgag gcgcatttgg atcgactgac
    51841 cgaccgcctc ctccaaagaa agagtcgaag atatcttcaa aaccaccgaa gccgccacca
    51901 gagaagccgc cgaatccacc aaatccgcca ccagctccac cagcaccgta atttggatct
    51961 gtgcctgcat gcccgtattg gtcatatgca gcgcgttttt gcgggtcact taaaatctca
    52021 tatgcttctg atacttcttt gaatttttct tccgcatcag gttctttatt gatgtcagga
    52081 tggtattttt tcgaaagctt acgataagct ttctttattt catcttctga tgctcctttt
    52141 gagagcccta agacttcata ataatcacgt tttgttgcca taggctttcc tcctattggt
    52201 tctcatcatt ttcacgtcgc ttgttatcat atcatatttt gtttgaaaca aaaaccgata
    52261 cttcaaacta tttttcaaaa gaaaaagcca aagtagcaac tttggccttc tctcgaaatt
    52321 cagtgaactg attatttatc gtcgccatcg acttcttcaa aatcagcatc aacgacatca
    52381 tctgctccgc cttgagctgc ttctgggttt tcttgagctt gttgttgtgc cgcttgttcg
    52441 tatagtttaa cagtcaagtt ttgaacgatt tcgttcaatg catcgcgttt agttttcatt
    52501 tcttcgatgt tgtttgcttc aacagcggct ttcaattcat cgcgagctgt ttctgctttt
    52561 ttcacttctt cttcgtccac tttgccttct aattctttca atgttttgtc cacagagaat
    52621 agcaatgcat ctacatcatt acgtaggtca acttcctctt tacgagcttt atctgcttct
    52681 gcatttgctt ctgcatcttt taccatacgt tcgatttctt cgtctgttag acctgaagaa
    52741 gatttgatcg tgattttttg ttctttttgt gtacctagat ctttcgcaga tacatttaca
    52801 atcccgtttt tatcaatatc gaatgttact tcgatttgtg gaataccacg aggagctgct
    52861 ggaatatctg tcaattggaa tcttcctaga gttttgttgt cagcagccat tgggcgttca
    52921 ccttgtaata catggatgtc tactgctggt tgattatctg ccgcagttga gaatacttgt
    52981 gatttacttg ttggaatcgt tgtattgcgg tcaatcaatt tagtgaacac tccacccatt
    53041 gtttcgatac ctaatgacaa tggtgtaacg tcaagtaaaa caacatcttt cacatcacca
    53101 gtgatcacgc caccttggat agcagcaccc atagcaacta cttcatcagg gttaactgat
    53161 ttgtttggtt cttttcctgt ttctttacgt actgcttcta caactgcagg gatacgagta
    53221 gatccaccga ctaaaataac ttcgtcgatt tctgattgtg ataaacctgc atcttttagc
    53281 gcttgacgta ctggtacttt tgtacgttct actaagtcag ctgttaattc atcaaatttt
    53341 gcacgtgtca atgtcatttc caaatgcaat ggtccagatt ctcctgctgt gataaatggc
    53401 aagctgattt gtgtgcttga tacgccagat aaatcttttt tcgctttttc agcagcgtct
    53461 ttcaagcgtt gtaaagccat tttgtcttga gacaagtcaa tgctgttttc ttttttgaat
    53521 tctgctacca tgtagtcgat gattttgtta tcaaagtcgt ccccacctag atggttgtcg
    53581 ccagctgttg acaatacatc aaagacaccg tctcctagtt caaggataga tacgtcaaaa
    53641 gtaccgccac caaggtcgaa tactaagatt ttttcgtcgc gatctgtttt atctaaacca
    53701 taggcaagag cagctgcagt tggttcattg acgatacgtt ctacttctag accagcgatc
    53761 ttaccagcat cttttgttgc ttgacgttgt gcatcattaa agtaagctgg cacagtgata
    53821 actgcttttt cgactttttc acctaaatag tcttctgcga atcctttgat atattgaagg
    53881 atcattgctg agatttcttg tggtgtatat gatttacctt ctacatctac tttgtaacct
    53941 gcttcaccga tatggcgttt gattgatgaa atcgtatttg ggtttgtcac agcttgacgt
    54001 tttgcaactt cccctacttg gatttctcca tttttgaatg atacaacaga aggtgttgta
    54061 cggtttcctt ctgggttagc gatgattttt gcttcgtttc cttccaatac tgctactgca
    54121 gagttagtcg tacctaagtc aataccgata attttactca taattaacgt ctccttcttt
    54181 aattgaaagt gtaagtttta tatccgcaca attattgtgc aacaatgacc atggttggtc
    54241 ttaacacgcg atcatgtaat ttgtagcctt cttgtagtac ttctacaatc gtatcggctg
    54301 gtgtatcttc agtcgctgga acagtttgta ctgcttgatg aagattagga tcaaaggctt
    54361 ctcctttagc agggattttt tcaattcctt cttcttccag tgcgttacgc aaactttcca
    54421 agaccatttc cacgcctttt ttcaaacctg ccccttgatc atctgacact tctgtggcta
    54481 atgcacgttc caggttgtca attgatggaa gtaatttttt ggctaaatct tgtgaacggt
    54541 atttttgtaa ttgctcacgc tcattttttc ctcgatttgc catatttgcg atttcagcac
    54601 gagcccgcaa gtatttatct tccatttctt ctaactcagc ttttaatttc gctgtttcga
    54661 attcttccgc ttcagcttct gaaatacccg aatcttctgc agcttcgaca tcgatttccg
    54721 gttctggctg agcatctgtc atttctttat ctagttcttc ttgattttct ttcacgatac
    54781 agtcttcctt tcattattca gtcagctgtt tgattgctct tactaagaaa gagagaacga
    54841 tcagctgcaa atagcttcgt tattcacatt acgagtttga caagtcaagc gaacggtagt
    54901 aatcagcaag tttagctgct agttctcttc gataaacatc gactagaccg aacatccgag
    54961 aataaggcat actagtaggc cctaacaagg ctattgtacc tcttccatga ccatctatct
    55021 cgtaacttgc ttgaatcata ctcatattct gcaataaatc attgcctaat tcagcaccaa
    55081 tcttgatatg aatattgcta tccatcggag tgatcatttg tgtaagtccg tctgagtctt
    55141 tcataaaaga aaacatcgat ttgaactgat caagatcttg acggggctca taatccaaga
    55201 gattcatttg tccactgaca taaaccttat cttcaaaaac atgaccaaga acggtgtcaa
    55261 ataactgaga catcccttct gtcgtttgga aatatttatg aagaatcatc ggaatctccg
    55321 tacgaagttt atggtacacc gtcatcagag gatctccgac tagacggtcg tttacaatct
    55381 gtaccatttt ttctagttcc tgacttccca tatattcggg aagagtgaac acttggcttt
    55441 ctacattccc catatctgtt acgacgatag caataatctg tcgattattc aagggtacga
    55501 tacgaaagcc agtcagtcgg cggtctttta tttcaggtcc caatgaaaaa gtcgtatagc
    55561 ttgtcagctc agataatatc tcagcagatt gcttaataat ctcattgatt tcatgaaatt
    55621 ctctgcctag agactgacga atcagcagca aatcatcttc tgctacgcga gcaggtttta
    55681 acaaatgatc cacgtaataa cgatagccta aagcagatgg aatccgccca gaagaagagt
    55741 gagtcttcaa cagcaatcct tcatcttcta atgctttcat atcattgcga atcgttgctg
    55801 agctggcctt gactccctca gacatcaatg ttttggaacc aacgggcacg ccactactcg
    55861 tatagtgttg gatgatcaga cgtaaaatgt cgttttgtcg ctttgttaac atcttcctca
    55921 cctctcatta gcactcatat attctaagtg ctaatccact tataaatata gcaagaagcc
    55981 cttctcctgt caagagaaag actccatttt ttagcactct aaacacaaga gtgctaattc
    56041 taaataattg atgtaaatcc agttatatca acgtttcaat agtcctttat tgtatttttg
    56101 aacttttttt atttaaattc agataaaaaa caaatattct ttaaactatt tttcaaacaa
    56161 aaagcgctca aacacattgt tccccaaaaa ggtccctctt ggtgtcaaat aaacacggtc
    56221 ttcttcatta acaagtaacc cttcttgctc taattccctt agcacatcac cgtacaccga
    56281 ttcaattgtt ttttgatagc gatcatagaa atgtttttta gtaatccctg ttttttttct
    56341 tagtcctaag aacatttctt cttctatttg attttttcgt gtcaattttt cttcttccaa
    56401 taccgggcgt tcatttgctc gtaatgggcg taaatagtgt tggattggtc ctttgttgcg
    56461 gtaacgaata tctccaagat aaccgctagc accagctcca aacccaaaat agtgggcatt
    56521 gttccagtac atgaggttat gttgagattc atgtccggag agcccaaagt tacttatttc
    56581 atattggtga cgtccatgct tttccattgc ttcaatcgtc tcttcaaaca ttctggtttc
    56641 cgtttcctga tcaggcagtt cgagtcttcc ttgtcgtacc cagttcatga acattgtttt
    56701 gttttcgagg atcaatgagt acaaagaata gtgaggcaga tccaaagcca aagctttttc
    56761 caaagtatcc agatatcctt ctagtgtttg tcccggtaat gcataaatca aatcgatgct
    56821 tacattggta aaattttctg cttctaaaaa ttgcatagtt tgatacacat cttctgcggt
    56881 gtgtttacgt ccaatttttt tcaataagcg attatcaaat gtctgcactc ccatggataa
    56941 acgattgacg ccatagtttt tcattacttg aagtttttca cgggtcaaat cacctggatt
    57001 cgcttctaca gtaaactcat taccattttg aaaaggcagg atctctctag cacctgataa
    57061 cagtcgatca agttgtttag cagataaaga agttggtgtc ccgcccccta cgtaaagtgt
    57121 ttctaaattc gctgtcggat gactttctag cattattttc atttcattca gcagcatttc
    57181 cacatactca tctactggct gcccttctaa aaaaacttta ttaaaatcac agtaatagca
    57241 gatatgctcg caaaatggga tatgaatgta cgcagaaacc ttgttttctg cgggatttat
    57301 tgtttctatc attgaaattc tttctcctta cgtcgaaaag tcgtgcctgt tttcgacctt
    57361 cttaaaatcg cgttcaagca ccaactcatt gaaataagcc gcatatttag aatcaaggaa
    57421 acctagctct aaaaatgctt gcttattgtc atcggagcta cacggtgctt ttacagcctc
    57481 tcgataaacg gtaatcgcaa agctgacctt cggcattaag tcaaaatctg caaaaatatg
    57541 aaaagctatt ttcacagatt cctccttaag tgctcagacc acaacgcttt gcttacaacc
    57601 tctcatatac gcatactaaa cgtatttggc gaacaaatcc actaaaaaat ccaagaatcg
    57661 acttcttgga tgattttttc tttcattaaa ctggttacct agttatatat ctctagggtt
    57721 gttttcatgt ctgagtgccc gatatgattt atttttcgtt tctataatta ctttttgcct
    57781 tccagtttct tttaatattg tactcaagca agtgggaatt ggttcttttg tcatccatgt
    57841 atgcaaaatg ttataatgct ggtaaacaaa aatgattacc tgtcattttt atttagttcg
    57901 tatttaatta agttgactat ctgtatactc tgtctaaaac ttaagaattg ttgttttcgc
    57961 tgtcgctacc caattttaat gaatgtctgt aggttaaaac tgttgtcctt gttatagata
    58021 gtaaaggaga gcttgaaaat gaaaactgcg attacgtttc tattagagga atatgccgat
    58081 tgggaaggtg cttatattac tagcacacta aaccaaaatg agaaatggca aaacaaaact
    58141 gcttctatcc aatcagaggt cacttccatt ggaggattaa aaacaaaaat cgattactta
    58201 atcgaacaaa tacctgaaaa agttgacctt tttattatga tcggtggcaa ttcatgggac
    58261 ataaaaaatc atcatttata tcaaataatc gataaattgt taaaaacaga cgtaccagta
    58321 gctgctattt gtggggcagt tgattattta gctcagagcg gattattgca aggttacaaa
    58381 cacaccggaa atgcgcaatt tccttggtta gaatcggaaa attatcagaa taaagaagat
    58441 tttatagaac aacaagctgt gaaagatcgt aatttgatta ctgcgaatgg aacagctcct
    58501 atagaattca cagacttgat tcttcaagca gtccattttg aaacagaaga aataagagaa
    58561 aaaacgattc gtctatacaa acttggattc tatgattact ataaaaagta cggagatcct
    58621 ttctcctaat cattctcttc aattaaatac tccttatcaa tagtgtgaca agtaatttta
    58681 ctgatgatta tttgtcacac tttttctgac atttatcaaa gaagatacac tctatttata
    58741 ttcatagaca aggttttacg gattcaaaaa ttcaggatta tgctatactg gtattaaaaa
    58801 aataatgagg tattttatat gaaaaagtta ggttttattt tattgttggt ctctttattc
    58861 cttgtaggat gtacgtctcc tagtaaagaa aatagtgatc catctgcgac cacagacaaa
    58921 agttcaatca gacaaaccag ttcagctgaa aaatcaagta ctcagaaatc agcttctact
    58981 gaaacgaata catcttcaac aagcagtaaa gtctcagagc ccaatacttc ttctacatct
    59041 agtagtacag ttgagacaaa tatttcttct tcaacaatag acacaacctc ctcacagtct
    59101 tctcagtcaa tagatccgtt agcaggatat tctgatctac aaattgagta cgcacgtgtt
    59161 tggctagcta ttagaggtaa tacttttaga gatacatcgg gtgatttcga attacatgtt
    59221 attcattatc ctgcaggaac acctatcgcc ccttatgatg cagggagtgc agtctatccg
    59281 aaagatgtgg ttatgctcac tgggaaatac agttaccagg gagttttagt gtattcaagt
    59341 aaccatgacg ggacaatcac tagttatcca gttccttcac attggcaaat gcctgcagat
    59401 caaacatctt atccagcgtt cattagagaa acaactcaag aaatcattga taatgcatct
    59461 gtagtagcta ttcctacagg aaatcccaat gacgtgaaac agttaatcga tgtgacagtt
    59521 atagataatt agactttcta atatgttata caaaaagaag ctgacagcat tttgtcagct
    59581 tctttcactt tcttttctat ttagatttat tggtctttga tagactccaa ggcaggaaaa
    59641 aattttttaa ataaacgttt gcaaaacagt cgcttttcta tcttctaccg ctacttctgc
    59701 ataggcacca ttaatcaatg tcagttgtgg cggtacatga ccacaatcaa tatcatacaa
    59761 gatcggtagt tttaattcct ttgacagatc ttcgtataca tccttcattt tataatctaa
    59821 caaatcctct gccgcacttc taccgaacat gatccccgag ctgccatcaa accagcctgc
    59881 cagtttcatc tgaacaagtg atcttcttaa atcaactgac gatagctcac agttttctag
    59941 aaaccacaag atcggctttc catcattata ctttctttta aaagattgga catctccata
    60001 aggagtaccg attaaatgcc tgatcgtatc aatacaacca cctaataatc gtcccttcat
    60061 ccttactgca tctccgctga ctgattgcca atttgttggt tcagtgagat ggaaaacaga
    60121 agatgatgaa tgctcatggg gccacacttt ttgatacttt tcagaagatt gctgtagaat
    60181 cgattctcct tctcttgttt tcagtacact ttcccacatt gctgtcgttt catccaagta
    60241 ctctcctctt aaatcaataa ggttagttcc atgtgcagtg gctatccctg tttttaatgt
    60301 gacagcaagt agcaacgtac taatatctga ataacctact atccattttg gttgtagagc
    60361 atcaaaatcg acaaaatcga gaatctcaat caataattct cctccccaag tcggaaagat
    60421 catttggata ttttcatctt gcatcatttg attgaattca tctgctcgtt ttcttgctgg
    60481 acctgatttt tccttatctt gcgtccaaag cgtctttcca gtaactactt ggaaagattt
    60541 ttcttccatt ctctttaaag ctgattcgag taacgaatgg tgttcctctg atacgcctga
    60601 ggatggtgca gtaaccccaa tcgttgcatt tctttctaat aatggataac ttatcatgtt
    60661 gcttcacctc caagtatgca ctattttact tggttaattg tttttttcgt ttgccggcat
    60721 caaaaatatc ggcatctcaa gtagctggat gattttgttt aagtcaaccg tttggatgac
    60781 catcgtttga tctggtctac ctggtgcaaa aacaagtttt tcatttgata agagctcttc
    60841 atcaataata atcggaatct gtttttcata accaaacgga gaaacagcgc cctgcttttg
    60901 tcccgtttgt tcttccatgc gttctgatga aacaatagaa agccttttac cgacgatctt
    60961 ccctaatgct ttgaaatccg tttgtttcgt agtaaaagtc agatatacgt agttattatc
    61021 ttttttatct tttaagaata agcttttggt ctctgtacct gtaaatcctt gttctttctt
    61081 tattaccaaa gcatcttcat ttgtataaat ggctcgatga tgatacaact caaaatatat
    61141 attttcgtgt aagaatttct ttgccaagtc aatcattttt atgtctcttt tctattttat
    61201 tatttgagac atcttatcat ataaatatag cggttacaac attacttgtg ttttgttcgt
    61261 tttttataca taactattgt ttttctggta aaataaatca aaccacttaa tggaggcgtt
    61321 ttagaatgga aaaatttcag ccgatcatca atcaaatcaa agaaaaagaa catcaacaaa
    61381 agatcaaaga cctttttgct aagataacag aaacgtatcc ccagctagac acaactgtaa
    61441 aatggaacca acctatgttt actgaccatg gtacctttat tattgcattt agttttgcta
    61501 aaaatcattt ttctatcgca ccggaaaaag cagcgattcg tgcccttgaa aaaaatatcc
    61561 aagaagcagg ctacgtatat acggataacg tcatcaaagt tccttggaaa agtgtaatca
    61621 actgggaatt gattgaacaa ttgatttcat ttaatattga agataaaaaa ggtcatgata
    61681 aattttggcg ataaagcttt atacgaataa accttttact ggcgaggaaa ctattcatca
    61741 ccttatacag gttttgttca atcctatcct ttttatcatc cctggttaaa cacttaattg
    61801 acaaagtatc tgctattttt ataaggagtc tttcttgtgc tgaaaaaaat cactgattga
    61861 atggctttga attttctact tagtaaaatt attttttcag caattttcct gcaaaacttt
    61921 tgaataagga aaaaatacga gaaaatatca gtgatctttc ataatactgc ccattatttt
    61981 caggtatatt taaatataat atcactttag gagagaacga atttctttag agaaataaaa
    62041 gttagaattt tctgacttga tttttacaat gaccttaatt aaaatcgttc tttctacatt
    62101 tcgtgattaa gcaaatatca actaagtcag tagaaccatt cacataggag ggtgaacatt
    62161 gaaagatttt tactcagtaa atgaattagc cgaacaatta ggtgttacta cacgttctat
    62221 cagaaattat cttcatgaag gaaaactaaa aggaacaaag gttggcgggc aatggaaatt
    62281 ttctgaacgt aatctttttg agttcctata cggagatcaa gcagaggaag cagcaaaaga
    62341 aatgcagcga ttcatgctaa atgcaccaat cacgatgcgt ttcaaccttc aatatcgtga
    62401 ttttacagca atcaatcaat tccgagaaca attagtccag taccataacg atgtttacgc
    62461 aaataaaaaa gaccgtcttt tacaatacga tctttataaa gacaatcatg cggagatact
    62521 aatcggtggt aacttcaatt atgtcgtaaa ctttagtcaa tggatcaatg aaaaattatt
    62581 gatccagaca gatatttccc ttgtatctta aacaattaaa aagcgctaga aattccagag
    62641 atgttggaaa ttctagcgct atttttttat aagtacttac tgtttggttc aaacaaatat
    62701 ttttttaata aatgaaattt taccatcttt atcctcaaat aaagaccgtg accatgcttc
    62761 ctactacgat cagcaataat ccgataatcg ttaatttttt ttcttttggt gtcttatttt
    62821 catgcaggat gtacataccg cctaatgtag agataactac gtttagctgt gtaatgatat
    62881 atgcagtagc aaccccattt tcatttgctg aaaaaatata agccaatgct gacacactaa
    62941 agatggctcc aacgatcgtt gctttccaac tcttgtcttc agaaaatgcg gttggtttac
    63001 ggaaaatcac ataaatcact gcccctaaaa agacaccgat catttgcgga aagaaaatgg
    63061 aaagtccgct tgcatcaact agtttaggca atgcactgta tacccaataa ccaatacttg
    63121 ttgatgctaa tagactaatt ccttttgtga taccgccttt ttttccagga tcatcactga
    63181 ttgccgttaa agcagaacca aatacaagaa gaatgattgc tgctgctcca atgattttcc
    63241 ccatacttcc agaccattct ccaaaagcga agacaccaat caacgaggtt ccgactaact
    63301 gtaatgcagt cgaaattggc atcgttttag aaacaccaat caagttgaaa gatgtatact
    63361 gtcctgtttg tccaataacc caaaatgcac cagaaagtaa actaatcaaa aatgtagtca
    63421 ctgaaatacc agctggagaa gcgaataatt gaacgagtaa gccgacaagc accgctccaa
    63481 taccagttcc taatatctca tttgttggtc tgccaccaat ctttttcaaa atcagtggct
    63541 ggatccccca gccaactgcc gggatcaatg caatcaataa acccattttt attcaccctt
    63601 atccttttcc accttggaaa gaaggatata aagtcatccc accatctgca aatagtgtaa
    63661 tacctgtaac ataactggat tcgtctgaag ccaaccatgc agctgtcgcc gctatttctt
    63721 ttggttcacc tacgcgtcct agtgggatca tactttccaa gagttctttt tgttcaggat
    63781 catcaaattt tgccgcatta ataggtgtac ggatagcacc agggcctata ctattgattc
    63841 tgattccctt cggtgcatac tccattgcta ccgtttcggt aaataatttt accccgcctt
    63901 ttgaagcagc gtaatgagca aacgttggcc atgggatctg ttcatgaaca gaagacatat
    63961 tgatgatatt tcctttttta ttattctctg taaagtaatt taaagccgct ttcgttccga
    64021 taaaaacgcc agtcaaattg acttttaaca ctctttccca atcttcaagg ctaagttcat
    64081 gggttggatg ctgattttcc atcccagcat tattaaccca aacgtccagt gtcccaaaat
    64141 tttctaaagc cgtatcaagt aaacgctgta ttccttcttc agaactgaca tctgcttgta
    64201 cagagactgc ttttccgcct gcctcttcga ttgctttgac tgctttttct gctccttctt
    64261 tatccgagtt atagttgaca actacattca ttttttcttt cccgaatcgt tgagcaatcg
    64321 ctgttccaat cccctttgag ccaccagtta ctactgcgac tttgttttct aattccttgt
    64381 acatagtacc cactcctttt tcatacctaa acctgttatt acggataact tttatttccg
    64441 ccttaaagtg agtgtacacc aagatatata gtctaaagca aatgatacgc tctagcaatc
    64501 gttttcatga attgctagtg tccttttatt tctataaaga aagaggttgt gacagaagtg
    64561 gtcagcttca agaaatttcg gcttatttcc gaagaagcta cttctgaaaa accatttatt
    64621 tggaaaaaaa ggctgtgaca agacttttgt cacagcccct ttcctgggct tatttatcac
    64681 ccattttatt gtaattgcta gttatacata aacaagagat tttatgcata atgttttatt
    64741 gctgagaaaa atattcagct gttgcttgtt catcctcctt gagttgttca atcaattcct
    64801 ctacactaga aaatttcact tgatctctta aaaattgatt ccagcgtacc gcgacatgtt
    64861 caccatagat atcttgatta aagtccaaaa tatacaactc tacagtcagc tcccgtcctt
    64921 caccgaatgt atcattatgt ccaattgaac ccatggctgg ataccatgtt tccccaattt
    64981 ttatttccga cacataaaca ccttctttag gcaaatgaac cgtgctcttt actttgacat
    65041 ttgctgtagg gaatcctagt agtctgcctc gtgcatcgcc atggacaact accccttcta
    65101 cctcatatgt gcaacctaat agttttgctg cttcttttac ttgtccgctg tctagtaatc
    65161 cacgaatacg ggtagagctg attttttcac cttgttcttc ttctttagaa actgtgacga
    65221 ttttgaatct tcctttggca tattcaggaa aatgagcgac atctgcaatg tcttttggtc
    65281 catacgtata atcaaaaccg gaaacagcat attttgcatg taaccctacg atgtattgat
    65341 caacaaattc ctgcggtgct aaatgagcaa aagaagaagt aaaatcaact tcatataaat
    65401 aatctatacc caaagcggcc attttttctt ctttttgctt aaggctagtc aaatatttca
    65461 cgctgctagg atcgatcttt ttaaagacaa tagatggatg ctgattgaaa gtcatcaatg
    65521 ctaatttcaa tccttctttt tgtgcaattt ccatacctgt ctttatgact ttctggtgtc
    65581 cgatatgcac gccgtcgaaa aatcccagca ctaaaacgac atcgtcttct ggaatttgtt
    65641 ctgattggta aggatgtctg atcttgatga tattcattcg ttattcctca tttctcaata
    65701 ctttactagg ttttaatttg tttttttctt tcgggtttgg ctgataaata ctgacaactt
    65761 ttcctttata aaacaaagca atttcttctg acggcatttc tgggagcgca aatacagtat
    65821 aatcaagtct cataccgttt tttactttct gccatacttc atcagtaata tctactcgtt
    65881 tgaaccgttc cactcctttt tctattggca gcaaacaatc atcgattgtc ccatttttca
    65941 cagcttgagc tacttcttct aatgtcagag catccttctg ggacataccg gcacttgctg
    66001 ttcgggtcag atcagacatg tgcgcagggt aaccaagttt cttgcctgta tctacagcta
    66061 atgtgcggac ataggttcct ttcccgcatt ctacttcgaa gcgccaagaa atggttcctg
    66121 tcacttcgtc tcttgtcaat tcacttgtcc ggataaaacg gtaaatctga gcctttctaa
    66181 caggacgctc cactgtttca ttattgcggg catattcata taaccgctta ccgttgactt
    66241 ttaccgctga gtacattggt ggtatctggg tgatctcacc aataaatgaa gccatcactt
    66301 catctatttt tttttcagat aaagacatat ctactggttt tgtttctacc cgttctccgg
    66361 atcgatcttc cgtcgttgta ctgaaaccta gagttatctc gcctacatag attttcccag
    66421 aatctgtcaa atattcgata acttttgtgg cttttccaat acaaatgggc aacacaccgt
    66481 ctacgtctgg gtcaagcgta cccccatgtc cgattttttt cgtatgtaag atttttctta
    66541 atttgaatac gcaatcatga cttgtcattc cgcgttcttt ccataaaggt aataacccgt
    66601 ccatgtcttt tctccatttc atttttgatt taactgaatt attataacac attgcatcaa
    66661 ttactgacga atttgacatc ataatgaacg gtttttattt ttcggcaata aaaacgtaac
    66721 aaaattcatg ctcacgtaaa tagaaatcat gttatgcttt tttaaaggag ggaatagaat
    66781 ggaagatttt ttctttgcac catttgattg gatttatggg tggcttacag gtaaatagtt
    66841 tggttttcac ttcccaaaaa cgaaaaaaaa gactggccat tcttccagtc ttttttccgt
    66901 tttttttatt tattttttca gtttcttaat caatgtaaaa aattctattt tgcgggatcg
    66961 attttatcat tttattggtc aagatttttc catttccaat ccaatacttc tggcagatca
    67021 ataccatttt cacgaatata gttttgatgt tcttgtaatt tctgatccat ttttttcgca
    67081 aaatcttctg cttgacttcc tttgattttt aaagctgcgt cttttgccaa atgataacga
    67141 tcaagttcat ttactacacg catgtcaaat ggtgtcgtga tatctccatt ttctttgtag
    67201 ccatgaatca ttaaatgatg gttatgacga tcaaagaaaa tcgtgcggac caatgtttca
    67261 taaccgtgga aagcaaataa gatcggtttg tcttttgtaa aatattgatc aaattcttca
    67321 tcgctcaacc cacgcggatc ttgacttgga tgacgtaatt tcaataaatc tacgacattg
    67381 atgaaccgaa tttttagttt tgggaattct tccagcagca aagttacagc tgctaatgct
    67441 tctaagttag attccgttcc tgcagcagca atgaccaatt caggttcctc ctcttttgct
    67501 gtcgaagccc aatcaatgat tttcaagcct tcattcacta agacggctgc ttcttctgct
    67561 gagtaaaatt gagcacgcgg atgtttggaa gagatgatca aattgatttt ttctgacgag
    67621 cggaatgctt tatccatgac tgcgagcaat gtatttgcat ccgcaggcag atattcacgg
    67681 atgaactccg ccttcttttc tgccaaatgt gtcaatattc ctggatcttg gtggctatat
    67741 ccattgtgat cttgctggaa gactgttgag cttgcaatga gatttagcga aggataatca
    67801 tttcgccaag aaaggtcatg tgatttccgc atccatttga agtgctgagt caacatagag
    67861 tcaaccactc gcaagaatga ttcgtaactt gcaaaaaacc atgccgtcca gtcagaacgt
    67921 acccttctaa gaacccttca tcttggtgtt ccgataattg actgtcgatg acgcgaccag
    67981 atggcgaaag ccattcatca ttttctggtt cgattttttc catccattgg cgatttgtcg
    68041 ttttgaaaac ttgattcaat cggtttgatt ttgtttcatc tggtccaaat atacggaaat
    68101 tttctggatt tttctcaatg atctcgcgaa cgaatttacc aagttcggtc atatcttctg
    68161 ctttaacgga gcctggtttt tcaaattgca aagtatattt tttccaatct ggcataataa
    68221 gcggtcttgg atcgattcca ccattggtga taggattttt tgccattctt tggtcaccag
    68281 taggcgcgat ttctctgatt tcttctaaaa tacgtccttg tgcatcaaat aatttttctg
    68341 gttcatagga tttcagccaa cggagtaaag catctgcatg atccatatgt tcttgatcta
    68401 caggaatcgg tacttggtgt gctcggaagg ttccttcaat tggttccccg tcccattctt
    68461 ttggaccggt ccatcctttt ggtgtgcgta cgatcaatac tggccatttt ggcatcacga
    68521 catctgttgc tgtcttcagg cgagcttctt tttggatgga tttaattttc tcgattgctt
    68581 gatccatttt ttcagccata acaggattta atttttctga atcatttcct tcaataaaga
    68641 aaggttccca gccaagtccg ttaaagtaat ttgctaattc tccatctgat ttacgtgcca
    68701 agatcgttgg gttggctatt tttgcaccat ttaaatgaag gatcggtaaa acagctccat
    68761 ctatcactgg attgataaag acatttgaga accagcttcc agctaaagga ccggtttctg
    68821 cttcaccatc accaatcacg acagcagaga ttacttcagg attgtctaat acagctccga
    68881 ctgcatgtga aagagagtat ccaagctctc cgccttcatg gatagaacct ggtgtttctg
    68941 gtgctgcatg agaagcaatg cctccaggaa atgaaaatcg tttgaataat ttttgcattc
    69001 ctgtctcatc ttccgttact tctggataga tctctgtgta acttccatct aaataagcat
    69061 tcgataccat gacttgtccg ccgtgtcctg gcccttcaat ataaaacatg ttcaaatcat
    69121 atttattgat gactcggttc aaatggacat aaataaaatt ttggccagga atcgttcccc
    69181 aatgaccgat tggatgtttt ttgacatctt cgggtttcag tgtacgtctc agtaaggggt
    69241 tatctttaag ataaagttgc ccaacagaaa gataattagc agcacgccac caagccgtca
    69301 ttttatcaaa gtattcttta ctagaataat ccatacataa cactcctttt cattattact
    69361 cttattctag cgcagatact cccaattgaa acctaataag cacttctgtt catttgtttg
    69421 gattttatat ctagccaaat gaacaggtat aaaaaaccac gaaatttttc ctttcgctga
    69481 cgttttttac attgatccaa aaaacttgtc gttatcacaa tggctgttcc gcagttcatt
    69541 tcgctcctca tcatgcataa tttgctgaat gacgctgggc cagttaacac attgctggaa
    69601 aactggggct ggatcgagca attcctttcc tgattgatcc gttttatgta aaagtctctg
    69661 ttatctttgt caatatgtga attggtatcc cagctactat gctaatttct acagggatta
    69721 tccaaaattt ggatcgtgac caaatcgaag cggcgtaatc ggaaatatca ataacttcaa
    69781 cgtgattttt cttttaactg tcaacggacc gacaaactca aacttttatg gtgcaggttc
    69841 cactgatctt ctagttactt ggctatacct gactgtcact aaaatagatt acaatctagc
    69901 ttccgttatc ggtatcttga tctttatcta tatgcaaaaa tttatatact actagaaaaa
    69961 agaaagtcga attttttact tttctttttc tcttttttgg ttagctgaca cgccgcaaga
    70021 ctaaagtcat ggaactctta ggtaatacgt cttaatgaaa acaaaaaaat cccgcaaccc
    70081 ctgatttcac aggatttgcg ggagtttttg attagtcttt gttcaagtcg cgaagcaatt
    70141 catcgatatg gttgccatag acaactgatt catcaagttc aaagaacaat tcaggtgtct
    70201 tataaatact tagattgtgc cctaactctc gacgaatcaa tcctgatgct ttattcaatc
    70261 catcttgtgc tgttttctta tctgatgcta agtcagataa aatgctgtaa tagatcgttg
    70321 cttgctgtaa gtcccccgta actttcacat ctgtgatcgt tacgttctcc acacgagggt
    70381 cacggacctt tttgcgcaaa atatcattga cttcttttaa gatttcttga ccgactcggc
    70441 ggtcacggta gttagccata atgattggcc tccttttatc agtttttagt catttttgac
    70501 ttcttccatg ataaatcctt caattacgtc atctactttg atgtcattga atttttcaat
    70561 cattgcacca cattcataac ccattttgac ttctttcacg tcatctttga atcgtttcag
    70621 acttgcaagt tggccttcat agattacgat tccgtcacgg attacacgga caccgctatc
    70681 tctacgaata tatccttctg ttacataggc acctgcaatc gtaccaactt tagaaacttt
    70741 gaaggtttca cgaacgatca tttgaccggt gattttttct tcaaattcag ggtctagcat
    70801 ccctttcatc gcagtttcga tttcttcgat ggctttatag atgatacggt gaagacgaat
    70861 atcgacttct tcagtatcag cttgcacttt tgcctgcggt gtaggacgaa cgttgaaacc
    70921 gatgataata gcgttgctgg ctgctgctaa ggttacatca ctttcattga ttgctccgac
    70981 agctgaatgg acgattttta cacggacacc ttccacatca atcttcttca atgatgcagc
    71041 cagtgcttct gctgaacctt gtacatctgc tttgatgatt acgttaactt ctttcaattc
    71101 gccttctttc aggctttcaa ataagttatc caaagtcaca cggcttgtgg cagcacggtt
    71161 ttctaataat gcacgtttcg cgcgttcttc acccgctgca cgtgctgtct tttcgtcttc
    71221 gaagactacg aaacggtcac ctgcttgagg tacatcattc aagccagtga tttctactgg
    71281 cgttgcaggt cctgcttctt tatcgcgacg gccaagatcg tttgtcatta cacggacacg
    71341 tccgtaagta ttaccgacaa cgattgggtc accaacatga agtgttcctt cttggacaag
    71401 taaggttgac acaggacctt tacctttatc aagacgtgct tcgatcactg ttccgattgc
    71461 gcgttgtgtt ggatctgctt ttaaatcttc tacttctgcg actaacagga tcatttccag
    71521 caattcttcg atgttttggc cgaatttcgc tgagatctca acaaagatcg tttctccacc
    71581 ccatgcttca ggaattaact catactcact taattcttgc ataacatgtt gagggtttgc
    71641 acctggttta tcaattttat ttacagcgac gatgattgga acgcctgcag ctttggcatg
    71701 gttgattgct tcaactgttt gtggcatgac gccatcatct gcagcaacaa ctaagatcgt
    71761 gatatctgtg atacttgctc cacgtgcacg catacttgta aaggccgcat gtcctggtgt
    71821 atccaagaaa gtgattggtt taccatcaat atcgatctgg taggcaccga tatgctgtgt
    71881 gattccgccg gcttcgccgc ttgttacacg tgaatggcgt aatgtatcca ataaagttgt
    71941 tttcccatgg tctacgtgtc ccataatcgt tacgactggc ggacgtgaga ctaatttatc
    72001 tggatcgact tcttctgcct cgaagaattt atcgatatca gcaatgtcaa cttggacttt
    72061 ttcttgtggt tccatgccat agtccgtcgc taacagttca atcgtatctt tatccagtgc
    72121 ttggttttga ttgaccatga caccaagcat aaataatttt ttaatgattt ctgctggctc
    72181 acgatgaatt tttttcgcaa tatctgctac gttcatacct tcagtatact ctaatacatc
    72241 tggcaattca cggaatttgc gtggtggtac agctggttta gttgattgtt gctgtttgcc
    72301 ttttttacct tttttattat aacgattacg gttattatta ttaaatttgc cgcgattgtt
    72361 attgtttggt ttgttgttat tgttagtacg gttttgattg ccgccttggc tcgttccttg
    72421 acgattttgg ctgctggtat ttcccgtatt attttggttt gttgttggtt tttttccttg
    72481 attcacttga ccgctccctt gaccgcgatc ttgataactg cggttatttt tatttttttg
    72541 ttgattgttc gttgtttctt ttttacgttg atcgttcggc tgttgattgg ctggttttct
    72601 gcttgcttgt tgtgcagctt gttgtttcgt gcttgggttt ttgaacgctt gttgcaattt
    72661 cttctcatca ttgctagtaa tcgcacccat atggtttttc acatcgatgc caagttgttg
    72721 tgctttttcc acgacgtctt tactagattt tttgagttct tttgctaatt catagattct
    72781 tttgttgccc atgcaatcac cttcctaacc ttcaattagc tccttggtct tcttcgcaaa
    72841 tccggcatcc attattccga ataccttgcg aggttttccg atcatctgcg tgatttctgc
    72901 ttcagaaaat agctcaaagc aaggaacttc ataatatgaa ctcttatctt ttatcttttt
    72961 tcttgtattc tcgcttgcat cggttgccac aaacaccaat tttgcttttt gtttgcggat
    73021 ttcagcaatg gtcagttctt cacccgtgat tagttttccc gcgcgcatcg ctagaccgat
    73081 gagattcatg gctttttgcc gattaactgt attcattttc caaataactc tttacgtgct
    73141 ttttggtgag tgacatagtc aagaagttct tgataaaact catctgttaa tgttgtttcg
    73201 agtactcgat cgagaatttt tttatcccaa gcttgttgta cttcttccgg ctcaagtgag
    73261 acatacgctc ctcgtccagg catttttcca gttggatcga tcgatacttc cccttctttt
    73321 gaacgggtga ttcggaccat ctctttttta ggtttcattt cacctgaaac cacggatttg
    73381 cgtaaaggaa ttttcctttg tttcatctct ttgcctcctt actaaagtta agcttctggt
    73441 ttttcttcga ccgtttcatt gttgaatgca attgtttcat attcatcgtc tgttaaatct
    73501 gactgaacga ttgcttcatc atgcagttct tctgtttctt tttgttgttc ttgattttca
    73561 taaaattccg tcatgtcaga ttctgatttg atatcgattt tatggttagt caatttagca
    73621 gctaaacgtg cgttttgtcc gcgtttaccg attgctagcg ataattggta gtctggaacg
    73681 acaactgtgc aggcctttgg atttgtctca tcgaagatca catccatgac ttgtgcagga
    73741 ttcaatgcat ttgcaatgaa tacagctgga tcttcattcc attcgacgat atccatgttt
    73801 tcgcctttta attcattgac gattgcttga actcgttgtc cctttggccc gacacatgta
    73861 ccgactgcat cgatatttgg atcatttgag cgaactgcca cttttgaacg atcgccagct
    73921 tcacgggcga tgctgacaat ttcaacgatt ccatcataga cttctggtac ttcttgctca
    73981 aataagcggc gcaataggtc tggatggctg cggctaacaa atacttgcgg acctttagac
    74041 gtattttcta ctcgggaaac ataaactttg attcgatcat gtggttgata aaattcattt
    74101 ggcatttgat cttgtttaga aagaactgcc tcaattttac caagattgac ataaatataa
    74161 cgtttatcct ggcgttcgac gattccttgc atgatgtctt tttcataagc actgaattcg
    74221 ttataaataa tcgttctttc tgcttcacgt acacgctgta aaataacttg tttagccgtt
    74281 tgcgcagcga tccgcccaaa atcttttggt gttacttcaa aacggatcgt atcaccgatc
    74341 tcatatgctg gattgattaa aagtgcatct ttcaatgaga cttccaactg tgaatccatc
    74401 acttcttccg ttacttcttt taccgcatag acatggatct ttcctttttt ctgatcaaat
    74461 tccacttcga cgttttgtgc ttggccatag tgacgtttgt atgcagaaac caatgctgct
    74521 tctaaagcat cgatcacgat ttcttttgag atcccttttt cagcttctaa agcgtctaac
    74581 gcatttaaca tttctttact cattttttct gattcctctc cgtgattaaa attggatagc
    74641 taagcgagct tttgcaatat tttttcggtc aaaagtcaat tctttttctc gtgtttttat
    74701 gcgtattttc aatgtaagct gttcagcatc aaatgattga agaaatcctt catattgttt
    74761 ttcgccatct actggttggt ataaggagac atggacataa tcaccaagtg ccttttcata
    74821 gtcgctttct tttttcaatg gccgctctgc tcccggggag gatacctcca ggaaataagc
    74881 ttgaggaatc ggatctggat ctgctgcatc aagtttttca ctcagtttct cactgacaaa
    74941 ggcgcattct tcgatatcga taccgccttc tttgtcaata aatactcgta agaaccagct
    75001 ttttccttct tttacaaatt cgacttcgac aagttcaaaa ttttgttcat ctaaaatcgg
    75061 tgtcaccatt tctgtgactg tttcaacgac gctactcaaa agtttcgcct ccttaaaaaa
    75121 ttaagtgcgt aattccatta aaaagagtga gcgaaaaatc cgctcactca cagttagtat
    75181 cattacctat aagaactata ccatactctg cttaaaatta caagcagaca ggaaaacaga
    75241 tgcttatagc atatcgaata acgataattg attttcatct ggtagatctt tcaatacgcc
    75301 attgtcgttc atatattcga tcaatgtttt tgaaacttta ccgcgggtgg caagatcttc
    75361 tttggataaa aatggaccgt cttttcttgc ttcaacgatt tgttttgcca cgttggttcc
    75421 caaacttggg acagctctaa atggtgcgat caacgtatca ccttcaataa caaagttaac
    75481 ggcatccgat ttatacaaat caatcattcc aaatttgaat cctcgttcca gcatttcatt
    75541 ggctaactcc agcactgtca gttgattctt ttcttttacg gaagcatcta atcctttgtc
    75601 cgtgatttct ttcattgctt gtttcacagc atcttttcct ttgcacatgg agactagatc
    75661 aaagtcgtct gcacgtacag aaaagtatgc acagtaatac aaaataggga aataaacctt
    75721 gaaataagcg acacgaagag ccatcaatac gtaagctgca gcatgggctt tcggaaacat
    75781 atatttgatt tttgaacaag aatcgatata ccagtcgggc acattatttt ctttcatcgc
    75841 cgatagatag gtttctcgca attcatcagg gatcttgttc cattgtcctt tacgaacagt
    75901 ttccatgatt ttaaatgcca tcccgctatc taatccagca tggatcaaat aaaccataat
    75961 atcatcacga cagccgatta cttccgccag tgtcgcatct cctcgtcgaa tcaattcttc
    76021 cgcatttcct aaccatacgt ctgtaccatg agatagtccg gaaatttgca gtagttctgc
    76081 aaaagttgta ggatgcgttt cttctagcat ccctcgaaca aaacgagtgc cgaattctgg
    76141 aatacctaat gtccctgttt tggaataaat ttgttcctga cttactccaa gtacttcagg
    76201 accggcaaat atccgcatca cttccgggtc atccgtaggg atcgtttgtg gatcgatccc
    76261 tgataaatct tgaagcatcc gaataacagt tgggtcatca tgccctagaa tatctaattt
    76321 caatacatta tcgtgaatcg agtgaaaatc aaaatgagtc gttttccatt ccgaattttg
    76381 atcgtctgct ggatattgga tcggcgtaaa atcatagaca tccatataat cgggaataac
    76441 gatgatcccc cctggatgct ggccggttgt ccgtttgact ccagtagcgc cttttgctaa
    76501 tctgtcgact tctgcacttc gaaactgcag attattgtcc ctttcgtatc cttttacata
    76561 gccatatgct gttttgtcgg cgactgtacc aatcgttccg gcacggtaaa catagtcttc
    76621 gccaaacaat actttcgtat agttatgggc ttctgcttga taatcacctg agaagttcaa
    76681 atcaatatcg ggcactttgt ctccatggaa tcctaaaaat gtctcaaatg gaatatcatg
    76741 accgtctttg tttaagcgtg caccacattt tggacattgt ttttctggca tgtcaaatcc
    76801 agaaccatac gtaccatctt caaaaaactc ggaatattgg cactctggac aataataatg
    76861 aggggctaac ggattaactt cagtgattcc tgtcatcgtc gcaacaaagc tagagccaac
    76921 agagccacgt gaacctacta gatagccatc ttcattactt ttatgcacta gtttttgggc
    76981 gatcagataa ataaccgaga agccattacc attaatagaa ttcaactctt tttttaatcg
    77041 tttttgaatg atctcaggta acggatctcc gtacatttgt tttgcttttg tgtaactcaa
    77101 ttctgatatt tcatcttctg aacctggaat cttcggtgta taaagttcat ctttgactgg
    77161 aatcacttct tcgcagatat ctgcgatttt attcgtattt tctactacga tctctttcgc
    77221 tgtttcttcc cctaaaaagt gaaatgcagt tagcatctca tcggttgttc ggaaatggac
    77281 atccggcaaa ctatgacgat tcaacggatt cgctccgccc atagaattga tcaaaatttt
    77341 tcggtaaatg gcatcttctt cgttcagata atgtacatta cctgttgcaa caacgatttt
    77401 atccaaactt tttccgattt ctaccaaatt ttggataatt tcttccaaat catgttcatt
    77461 ttttaccaat tcttgctcga tcaaaggcgc atagaccgct tttggcataa cttcaatata
    77521 atcgtagaat tttgctcggt ttcttgcctc ttctacccct ttttgcatca tggcttcgaa
    77581 tatttctccc ttatcacaag ctgagccgat caatagattt tcacgcatct ttttcaattg
    77641 ggagcgtggt attcgtggga cgcgttcgaa gtattcgaca ttcgacattg aaatcagttt
    77701 gaacaaatct ttcagtcctg cctgattttt tgctaaaatc gttacatgga aaggtcgagc
    77761 ccttttgtaa gaatctcctt ctccgatatg ctcatttagc tgatcatgat aaagcatgtt
    77821 atgattgtcc attgcctctt tcacaaagat ccatgctaag tgaccagttg cttcagcatc
    77881 atagattgct cggtgatgct gttccaagct gacaccaaat tttttagata acacacctaa
    77941 tccgaaacgt ttgaattgag gatacagata tctagctaat tccaacgtat caatgactgg
    78001 attggccgct tcaggaatac cataccttgc gtagctagta ttcaagaacc ccatatcaaa
    78061 agccgcgttg tgggctacca aaattgtatc ttttgaaaat tcaaggaaca tccgcaatac
    78121 ttcttcttcc gactttgatc ctcgaaccat tccatccgtg ataccagtca gatctaccgt
    78181 tgttcgtgac aaaggatgtc ctggatcgat aaattcatca aagctttcga tcacatttcc
    78241 tttatacatt ttgactgcgg ctagctcgat gatcgtgtca tatactgcag acaatcctgt
    78301 cgtttccacg tcaaatacga catatgtggc ttcactcaat gcttcatgtg catcattata
    78361 agcaattggg acaccatcat ctacgacatt cgcttccacg ccgtataaga ttttcacacc
    78421 tgcttttttt ccagcactat gtgcttccgg aaaggcttgc gcaccaccgt ggtctgtaat
    78481 ggcgatagct cggtgtcccc atttccctgc ttgtgccaca agatcagaga tgctgtttgt
    78541 tgcatccatc gtactcatat tgctatgaac atgaagctct actcgttttt ccccttcagg
    78601 agcataatct ttgcgaggtg tatgtttgac ttctatgata tcttgcgcat tcatgaccaa
    78661 atcacggaca aacgtatctt cttgaatact tcctcgtacc tttaaccagc taccgacact
    78721 gatcgcatca aatacttgtt catctttttc gccgttcgag aattttttga cgataaatga
    78781 tgaagtataa tctgtgattt tcaaagtcaa gatcttgcgt tttgaacgta gttctctgac
    78841 ttctttgtcg aatacgtacc cctcaagtgt gactcttcgt tcttcttcaa cgatactgat
    78901 cattggtgtc gttggttcat cggctggaat atttcgtcct agctggatgt ggatgggtcc
    78961 ttcaagagct ggcgattgct cttttctttc ctttttcttt tgttcgtgga caactagact
    79021 ttcagctgct tgcttcataa aggcttctgc ctgttcttgt ttgcgttctt caaaaagttt
    79081 caatactcgt tccgcttgct gctcatccac ttctggttcg atacgaaatt ttgggaatcc
    79141 gtaactgacg aacaactctt ctactaatgg caagtattgt tgcttcaaat aagaaatagc
    79201 tcctgtactg tcgattggca agatgacttt acgatctttt atcacaggta cctgcgtttt
    79261 caatacttgc tgtgctagtg gtgtatcgca ttgctgattt tccaaagctt gggcccagta
    79321 atcttgcaag agctgttcat cgaatgtctg gtcatctgct aagatattca gtttgacttg
    79381 tgcaatatct ttaaaagcga tagtcagatg ctgagtcaat gaccgatata gcataatagg
    79441 caaaattttg gaaaaatgca gcgtaaattc ccataaacgc gatttacgat ggaccactac
    79501 actatccatt tcaccagcag taagcagtgg atgatttttt tctgcttcct ctagttggat
    79561 ttgttccaac agtttttcaa ataaatctcg tttttctgac aaagatatac gccctttctg
    79621 atgagaaaca atgcaattga tcgcatctta tcctcttctt tttcagtacc ttttagtata
    79681 ctcgtttttt ctgagtttta cattaaaaaa ttggaactgc gattcaaatc gcagttccaa
    79741 ttttaaaagc gaatcatcag attgtcaaaa acagctgatt cagctatttt tattttctgt
    79801 gttttaacgc ttattattcg ccttggttca agaggattgg taaagtattc accaattctt
    79861 ctttacgtac ttcaaccatt tcgccagttt tcttgatttt cacttctacg attccatcca
    79921 ctgctttttt accgacagtg attctgattg gacagccaat caaatcagaa tccgcgaatt
    79981 tcactcctgc gcgttcattt ctgtcatcaa ccagtacttc atagccagct tttgtcatcg
    80041 cttcttctag ttcattcgtc aggtttgttt ggtattcgtc ttttagattc atttggacga
    80101 tatgcaaatc aaatggcgca attccttttg gccagttgat tccttgttca tctgaatgtt
    80161 gttctacgat tgctgataat aaacgactta caccgatacc ataacagccc ataatcacaa
    80221 atttttctcg tccattttcg tctagtacag ttgctcccat agattcactg taacgagtgc
    80281 cgattttgaa gatatgtccg atttcgattc ctcgagtaaa ggcaagaaca ccattgttgt
    80341 ctggtgaagg atctccttct tgtacaaaac gaagatcttc ataagaaagt acagtgaaat
    80401 cgcgttctgg attcacattt ttatagtgga atcctgtttc gttcgctcca gtaatggcat
    80461 tcgctaaatc ttggacataa cggtctgcat atacttttac gtcatctgaa acaccgactg
    80521 gtccgacaga accaaactca gcacctagat atttttgtgc ttcttcttct gttgcttctt
    80581 ctaaaaagtc agcagataaa aagtttttca gttttacgtc attgacttca tggtctccgc
    80641 gtaccaaaac aaggacaggt tgttcatccg caatgaacaa tacagacttg atgatttttt
    80701 gaggttcaac agaaaagaaa tctgctactt cgtcaattga ttttacgtta ggtgtagcta
    80761 ctttctccaa ttcaagctgt gtttcatgcg atttttttga tacatagtag cttgtagcca
    80821 tctccaagtt tgcagcataa tcactttcag tcgaataaca gatcgtatcc tccccgattt
    80881 ctgagatcgc catgaattct tttgagtctt tcccgcccat tgcgccaccg tctccgataa
    80941 tcgagcgaaa ttctaagcca caacgcttga atacttcggt gtaggctttt tcgtaatctt
    81001 tatatgtctc gtccaaactt tcttccgttg catggaaaga atacgcatct ttcatgataa
    81061 actctcttcc gcgaagcaaa ccgaagcgag gtcgtttttc gtcacgatat ttaggttgga
    81121 tttgataaag atttaaaggt aatttcttat atgaattgat ttcattacgc atcaaatcag
    81181 taaaagtttc ttcgtgagtt ggtccaagga tcatttttcg atcattgcgg tctttgaaac
    81241 gatacaagtt tggtccatat gtttcgtaac gcccggattc ttcccaaagt tctgctggca
    81301 agatggcagg catcagcatt tctaccgctc cgattttttc aaattcttcc cgcataatgc
    81361 gtttcagttt ttccaataca cgatttgcta atggcagata tgaataaata cccgctgata
    81421 cttggcggat atatccagct cttagcaaga tttgatggct taatacttct gcatcatttg
    81481 gaacttcgcg taatgttgga atcaacattt ttgattgtct cattctatat actcctttat
    81541 ttcctcaaaa tagttatcgt ttgttattat accctatttg tcaacttttt ctagaaaaag
    81601 aatcgttgaa tatcgttcca tgtaactagc accatcaaca acattaaaaa tccaaagcca
    81661 gctaatgtca atattccttc tttttcttga cttaatggtt tcccgcgaat cccttcaaaa
    81721 atattcaaga ctaatttccc gccatctaag gcaggaatcg gaagcagatt gacgattccg
    81781 agattcattg aaagaagcgc catcaaacta ataacagttg ttacaccttg atttgctgct
    81841 tctgaagaca attggtacat catgacaggt ccgcctaatt tatctaaact gaaacctgta
    81901 aatagtgatc ctaaggcttt gaaaatttcc aatgaaccgc tgaaagcttg acgcgtccct
    81961 ccaatgatct tatccataaa acctgtattc attggggctt ttataccaag ttggccaact
    82021 ttttcgccat ttgactctac agatttcggt gtcacgtcga cagattgcac ctgaccttct
    82081 cgttcgatct taaagtctaa tgttttatcc ggatttttcg taatgactgt tgtcagatca
    82141 ttccatgaat ggatttcttt tccgtccaca ctgactacct catcattttc ttttaagcct
    82201 gcttctgccg cagctccatt aggcatgatc tctcctacgc gattagtgtt cgtcacttga
    82261 acaccacctt gcataaatgc cagaatgatg aataacagga ttgccaaaat aaagttattc
    82321 atgggtccag caaagttggt cagcatacgc tgccacaatt tagccgattg gaactgtacg
    82381 tcttttggcg caattctgat ttctgttccg tcgttttcaa taatcgtcgc atcgtgatca
    82441 acagggtagg ttactacttc tgtttcgtct ccattcacat aaccagtgat agtcagctca
    82501 tcttctaaat cataacggct caattccatc gggatagcat ttgtcaattg gattttctta
    82561 cttaaattta tcttctctac gatgccgtca gaatttagta aaagagaaag aggcattcct
    82621 ggtgccattt ctgtttcatc atccccattg cctgccattc gaacataacc gccaataggt
    82681 aataggcgaa gcgtatatgt tgtcccgtct tttgcttgat gcccataaat tttcggaccc
    82741 ataccgatag caaattcgcg aacgaggatt cctgatcgtt tcgcaaagaa gaaatgacca
    82801 aactcatgaa caatcactaa tataccaaaa acgatgataa atgtcagaat cgttttcata
    82861 gcttttttct cctttacttg ttttttgtgt tttttataaa acaacgataa aacactataa
    82921 ttttaccata gtataccaaa gacaccaata gtatcaatat aatgaaaaat aaaaacctgc
    82981 gtcttttatg aaattcacaa agaaacgcag gtatacttac taaataatgc caaataaatg
    83041 catgatagga aatacaaaca gcaaactgtc gaaacggtct aagattccac catggcctgg
    83101 taagatattt cccgagtctt tcacatcata atgacgtttg attgcagatt cgaccaaatc
    83161 accaaattgt ccgactgctg aaaaaataat cgtcatcaga agcatgacaa acataccatg
    83221 attaaatagt tcttttgctg ggtatagcaa taaataaaga aatgcgacta caacagcact
    83281 accaatacca ccgagcgcac cttcaatcgt tttgttgggc gaaatatcag gacttaactt
    83341 atgctgacca taacgtcgac caaccatata tgctccgata tcagttgccc aaacaataaa
    83401 tagaccaaat atcaaaacag ccaagctttc tgttcgtgca ttgacaaaat tctggaaacc
    83461 tattcccaca tacaagctga caagcacagg aaaacctgct tcatcaatcg tatacgtatt
    83521 tttagaaata actgatgttc ctaaaagaat cataactata agataaaata acataaatgt
    83581 acttacattc tctggaagaa agaaaaacca tctttctttt ggcaaaacaa gtaacactgc
    83641 accaacggcg gataaaactc cttcaaaact taagagtgtc aatcctttca tccgaaacag
    83701 ctcgtaaact cctattactg ctaagattgc tgctgtaagc tcaaccgcta tgcctccgat
    83761 ccatataatc ggaataaaca agactagcgc cacggctgct gtgaccacac gttgtttcat
    83821 gactgatccc ctttctcatc ttctgttttt tttacaccgc cgaatcgacg gtctcgattt
    83881 tgataagagg cgattgcttc ttcaagatgc gcaccatcaa aatcaggcca aagcgctttt
    83941 gtaaaataca gctcactata tgcgatctgc cataacagaa aattactaat tcgctcttct
    84001 ccacttgtac ggatcatcag ctcaggatct tgtaactctt taggcaagaa acctgtcatt
    84061 aaatgcttag caatcaattc atcatcgatt tcttctgcgt gtatttctcc ttttgctact
    84121 tcttcggcaa tttcttggac agcagtcacg atctctgctc tgcttccata attcaaagca
    84181 aaattcaata ccattccagt attgtttttt gtttgctcaa ttgcacgtct tacagcatct
    84241 tgcgtatgtt ctggcaatac gttttcataa cccatgacat gaactttgac attttcttta
    84301 atcaattctg gtacgaacgt atcaaagaag tcgacaggta gttgcatgag aaaacttact
    84361 tcatcttttg gtcgcttcca gttttcagtc gaaaaggcat aaagcgtcaa cactttcact
    84421 ccaagccttg atgctttttt tgtgactttc tttactgttt ccatgccttc tttatggcca
    84481 gcaactcgtg gcaaacgacg gttttgcgcc caacgaccat tgccgtccat gatgatggca
    84541 atgtgctgag gaattggtcc atcggtatta aattgaaatt cgcttttttc ttgaatatat
    84601 ttgttttttt gcggaaaaaa acgtaacatt ctttttcctc ctatacttaa aagattccca
    84661 ctatcttaag tattatagca atatctaact gtttttccta tgaaatcatt gtttttttat
    84721 ttaaaaactg aataattttt tcttttttta atttttaaat aaaagaaata taaataaaaa
    84781 cagaggaagc ggaatgatcc gcccctctgt ttttatgatt ttattaaact tccaataatt
    84841 ctttttcttt atcagcagcg atcttatcta cttctttgat gctgttatct gtcaatgttt
    84901 gtacgtcttt ttctaatccg cgcaaatcat cttcggtaat atcaccattt ttttgttgtt
    84961 ttttatattc atcgatcgca tcacgacgga tgttacgaat cgcgattttt gcattttctg
    85021 cttctttttt aacatcttta gctaattctt ttctgcgttc ttctgtcagt tgcgggataa
    85081 ctaagcgaat gacatttcca tcattggttg gactgattcc gatatcactt gccataatag
    85141 ctttttcaac atcttgaaga atgctcttgt caaaaggtgt gatcattaaa acacgtgctt
    85201 ctggaatttg gattgatgcc atttggttca atggtgttgg cgcaccgtag tagttcacag
    85261 taatacggtc caaaaggcta gcgttcgcac ggcctgcgcg gatttgccca agttcacgtt
    85321 gaagattttg tgctgctttt ttcatttttt cttttgcttc tgtcataatt gcatctgcca
    85381 tttttatttc ccccttacag ttgttccgat attttcgcct aagattgcac ggcgaatatt
    85441 tccgtgttca tttaaattga agacaagcag tggaatatca ttatccatgc ttagtgaact
    85501 tgcagttgaa tccatgactt gtaatccttt ggcaataact tccagatgag tcagttcttc
    85561 aaattttact gcatttgcat ctactttcgg atcagcagaa taaacaccgt ctacattgtt
    85621 tttagccatc aggataacat ctgcgccgat ttctgccgcg cgtaatgctg ctgttgtgtc
    85681 tgtcgagaag tacgggttgc cggtaccgcc tgcaaagata acgatccgtc ctttttctaa
    85741 atgacgttct gctttacggc gaatatatgg ctctgcgatt tgacgcattt caatcgaagt
    85801 ttgcacgcgt gtcggtacac ccacgttttc caacgtatcc tgtaaagcta aggcattcat
    85861 aactgtagct aacataccca tgtaatcagc ttgagcacgt tccatgccca tttgtgctcc
    85921 gatttgtccg cgccagatat ttccgccgcc cacaacgatt gccatttcaa cgcccagctc
    85981 gtgaacttct ttgatttctt ggatgatttc tttgattact ggtggtttga ttccaaatcc
    86041 tgcgtcccca gctaaagctt ctccactcaa ttttaagact acacgctgat atttcggtgt
    86101 gaccatgttc attcctccaa tattttctat tgccatttta ccatacttag atgatttcga
    86161 cactctaaga ctggtttttc ttgttttgct taaaaaaagg gagcgcacaa accgtgcgtt
    86221 cccgtctgtt attcaacaga attatttttt cacttggctc ataacttctt ctacaaagtt
    86281 atcttcgcgt ttttcgatac cttcgccaac ttcgaaacgt acgaatgttt taacagttgc
    86341 gccttttgat gcaacgtatt tttcaacagt catatcagga tctttaacga atggttggtc
    86401 caccaaagcg atttctgctt tgaatttctt caagcgtcct tctaccattt tttcaacgat
    86461 attcgctggt ttgccttcgt tcaatgcttg ttctgtaaga acagtttttt catgttctaa
    86521 ttcagcttct ggaatttgtg attcgtttac ataacgagga ttgatagctg ctacgtgcat
    86581 agctacgtct cttgcaactg tttcgtcagt tgttccatct agaacagtca atacggcaat
    86641 acgtccgccc atatgcaagt atccaccaaa tgcagcattg tcgtcttttt ctacaacttc
    86701 aaagcgacgg aagctgattt tttctccgat aacttgagtt gcttcgatca agtcagattc
    86761 aattgtacct ttatctgttt tgattttcat tgcagcttcc atgtctgctg gtttgttttc
    86821 agcaacaagt tctgcaattt cttttactaa atcttggaac atttcgtttt tagaaacaaa
    86881 gtctgtttct gagtttactt caacgattgc tgcagtgtta cctttcacag caactgaagc
    86941 caatccttca gctgcaatgc ggtcattttt cttcgcagcc tttgccattc ctttttcacg
    87001 taaaagatca actgcttttt ccatgtcgcc ttctacttca actaatgctt ttttcgcatc
    87061 catcattcct acgccagtca tttcgcgtag ttcttttacc attttagctg taacgtctgc
    87121 catgtttaac tcctcctgtg tgtttttctt tttaaaaaaa gctgcttcaa aggagagtga
    87181 ggcttgtcgc ccagcctttg aaacagctcc atcattcaaa attattctgc tgaagaattg
    87241 tcgccttcaa caacatctac gatttcttcg attgatgttg ctgtgttttc ttctgtgaaa
    87301 tcttcttcaa ctacttgatc ttcaccttgg tttccttcga tgaaagcatc agccattttt
    87361 gaagtaatca atttaacggc acgaattgca tcgtcgtttg aagggattac tacgtcgatt
    87421 tcatctggat cgcagtttgt atcaaccata gctacgattg ggatatttaa tttgtgtgct
    87481 tcttgaacag caatacgttc tttacgtggg tcaacgatgt acattacatc tgggattctt
    87541 ggcatatcag cgataccgcc taagaatttt tcaagacgtt cacgttcttt gttcaaacca
    87601 gcaacttctt ttttaggtag aacttcaaaa gttccatctt cttccattgc attgatttgt
    87661 ttcaaacggc tgatacgttt ttggatagta tcccagtttg tcaatgttcc gcctaaccaa
    87721 cgatggttaa cgaagtattg tcctgcacga gttgcttctt ctttgattgc ttcttgtgct
    87781 tgtttttttg tacctacgaa taatgctacg ccgccttctt cagcaacgct cttcatgtaa
    87841 tcataagctg catctactaa tttaactgtt ttttgcaagt caatgatgta gattccgttt
    87901 ctttctgtga agatatattt cttcattttt ggattccagc gacgagtttg gtgaccaaag
    87961 tgtacgccgg cttctagtaa ttgtttcata gaaattactg ccatgtttgt ttcctccgat
    88021 ttggttttat ttttcctctt cttatcttct accttgccgg caaacttttt caagcaccta
    88081 ccgacaatcc aataagaatg tggatttgct gatgcataaa gcaccctcag ctattataca
    88141 gacaaaagat ccgtatcgca agagcaaata tacttttctg ctcaacattc aatagtttac
    88201 ctgaaagata aaaagaattc aagaaaaaca gtagatttct ctttgtttct ttattatcct
    88261 ttttccataa aataatttta ggtataaaag acgaatatta ttgggcaatc cttctttttt
    88321 ttgttatgat acatgtgaaa tctttcgtaa aggagaaaga aaatgcgcaa agctcaaaga
    88381 catttgctga ttaaacaagt cattgaagaa ttcccgatcc gtacgcaaga agaactatta
    88441 aacaaacttg ggcattatgg cgttaccgcc acgcaggcaa cgatttctcg agatatccgt
    88501 gatctaaaaa tcgtgaaggc acctgatgaa aatggcgttt cccgcttcgt attgtttcgc
    88561 gaaaaaggaa ctcctgagac taggactgag gaagaggatc ggctggttca aatgattgaa
    88621 gacattgtat tgaaagtcga acgagtccac tttttgacga tcgtcaatac cttgccagac
    88681 aatgctcatt tatttgcatc tgttttagat gagatcaaac ctccctctat tgtcagtaca
    88741 attgctggat tcgatacgat catggtcatc tcggaaaatg aggaggacgc aaaacgagta
    88801 gaagaatttc ttcaccatcc aactgaagta tcactttttt aatcagagca cgtattccta
    88861 atatggaatg cgtgtttttt tattttcaat attttcctta ttgaataaac ctttacactc
    88921 tttacaaaaa tacatcattt tttattcaaa tttttcaaca ccttgattga atcacaataa
    88981 tcatcattta tattggatgt taacaagagc agcttcttgc tctttgtgta tttcaaaaaa
    89041 gaaatgaaag gaaatcatat gtataaatta ttaacttctg gaccattgac gacttctgaa
    89101 acagtgaaaa atgctatgct gatcgatcat tgtacttggg atcaagaata caaagaaatt
    89161 acacaatgga taagaaaaaa attattggat cttgctcaag tatcggaagg aatatacaca
    89221 acggtcttaa tgcaaggtag cagctccttc ggggtagaat cggtattaag ttctgtgatc
    89281 aggccagaag atactgtact gatttgttca aacggcgcat atagacaacg aatgatcaac
    89341 atgtgcgaat gtctgaaact gaactatacc gtttatgagg tatcggaaca tcaaatcctc
    89401 caagctcatg tgattacaca gctgattgaa gagaatccgt ctatctccgc actagcaatg
    89461 gtccatagcg agactacttc cggtattttg aataatttgg aagagattgc tgctgtcaca
    89521 caagaaagag atcttttgtt tatagtggac gcgatgtcaa gctttggtgg gataccgatt
    89581 tgtgtagccg aactagggat tgattttttg atttccagct caaacaaatg tattcaaggt
    89641 gttccaggct tttcttttgt acttgctaat aaagcggaac tggaaaaacg aaaaaatgtt
    89701 agccgaagtt tgtcacttga tctatatgac cagtaccgcg tgatggaaaa cgagaatggc
    89761 aaatggcgtt tcacttcccc tacccatacg gttttggctt ttcaacaagc gctgaaggaa
    89821 ctagaggcag aaggaggaat cgaaactcga tattcacgtt atctcgccaa taatcatgtg
    89881 ctacgacaaa aaatgacaga gatggggttc cagcctttca ttcaagaata tcaggggcca
    89941 ttcatcacct cttttcttta ccctaaggac tggcgatttg attttaatca tttttatcag
    90001 tatttaaagc aaaatggatt tgtgatctat cccgggaaaa tcagcgatca tgaatgtttt
    90061 cgtatcggaa atattggcga gatctatccg gaagatattt tggaactgac agcaattatc
    90121 aaagactata aggagaacgt taatgattaa aactgtaatt tttgattggg caggaacaac
    90181 tgtggacttt ggctgtatgg ctcctgtcca cgcttttaga aatgcttttc tagaaaaagg
    90241 aatccaactg actgacaaag aaatccgcta accgatggga aaattaaaat gggatcatat
    90301 ccaacagctt ctttccctcc cttctgtcaa aaaacaatgg atagctattt atggacaact
    90361 acctcaggaa aaagaggtgg aggaattgta tcaacaattt gaacattatc tgtttaaaga
    90421 tttggtcaag cattctacct tgaaacccga cacattggaa acgatcgaac ggttgagaaa
    90481 cgctgggatc aatattggtt ccacgaatgg atttaatgct cctatgatga caatcgtagc
    90541 agaaaccgca aaaaaagaaa ggtattcacc agacttcatg gcaacttttg aagacgtcga
    90601 agggtatggt cgaccgtttc cttatatgat ccataaaaac atgcagtact tcaaaaacaa
    90661 gtcggttgat gaagtaatca aagtcggaga tacggtctca gatatccagg aagggaaaaa
    90721 tgccggagtg ttgacagtag gtgtaattga aggtagttcg ctaatgggga tttcttatga
    90781 tgagtaccaa aaattagaga tggggaaaaa gatcgtttaa aacagtctgt tgctcttaga
    90841 ttccaacaag ccggcgctga tatttgtgta aacaatttaa aagagttaac agaatacatt
    90901 ttgtacgctg acatgaatcc agaatgactt ttatacaaaa taagaggttg tgaaaaagct
    90961 gtcctgtatc aagtaataaa aacagccaag caaaaatagc tcctcatatt tttcgtttgg
    91021 ttaggcttat taccgcagat gcaagctttt gaacaccgtt tattcgaaaa aaaaaaggga
    91081 gctgtgacac gacttttgtc acagtcccct tatttgcaaa caaacagtgt ttaagagaca
    91141 acctctccac taaacggtgt tcattcagct gactctcggt atttgctcaa aaaacgataa
    91201 aatttgaaaa gctattttct cttttgtttc tctaatactc ggatcagaac gctgatttca
    91261 cattctcttt ttcttacatc ttatctggtg catgaagtcc tagcaaacga aggtcttctt
    91321 tcaataatac agtcactgca taaactagag ctaagcgtgc ttctttttgt tcatcatcag
    91381 ctaaaatctt cgtatgagca tagtatttgt tgaatgcttg tgctaatttg attgcatgtt
    91441 tcgcaatcac tgacggttcg tatttttccc cagcagacaa gaccgtttca gggtattttt
    91501 gaactaattt aaccacttcc cagctggtat cgtcattcaa tgcatagtct gctgtttctg
    91561 aagggacaaa tcctgctttt tccaacaggc tgactgcacg agcatgtgta tattgcacat
    91621 aaggtccagt ttctccttca aatcgaacaa cttcttccag gttaaagtca aatgtattca
    91681 gtcgatcgtt tttcaaatcg tggaaaatga ctgccccaac cccaacttgt ttagctacag
    91741 catctttgtt ttccaaatca gggtttttct cgctgatttg ttctttagca gattggattg
    91801 cttcatttaa tacttcttct aataagacga tctttccttt acgagttgat aattttttac
    91861 caccttgcgt gatcaaacca aatggaatat ggtgcatgtc gtcagaccag tcaaagccca
    91921 tttccttcaa gacagctttc aactgtttaa aatgatagct ttgttcattc cctactacat
    91981 atagagattg tttgaagtcg taagtacgtt tacggtacaa tgcagcagct aagtcacgtg
    92041 taatgtatag tgtcgcaccg tctgacttct taatcaacgc tggattcagg tcataagcag
    92101 ataggtcaac gatctctgca cctttatcct cgttcagcaa atgtttttct tctaaaagtt
    92161 tgacgatttc atccatcttg tcattgtaga aagcttcacc gttcaacgaa tcgaaacgta
    92221 cttccagcag atcatagatt ttattgaatt ctttcatcga ttcatcacgg aaccattgcc
    92281 ataattgaat agcctcttta tcgccttctt ccagacgttt gaaccaagca cgagcttctt
    92341 catttaattc tggttctgtt tcagctactt catggaattg gacgtataaa cgaagcaatt
    92401 cattgattgg ttctgcttta acagcttctt ctgtacccca ttttttgtaa gcgacgatca
    92461 gttttccaaa ctgtgttccc cagtcaccta aatggttgat gcggattggc tgataaccga
    92521 ttttttccat aatgaaaccg atcgaattac cgataactgt cgaacgcaaa tgtcccattg
    92581 agattggttt ggcaatatta ggagaagaca tgtcgattgg tactgttcct tgattcccga
    92641 tgttgctatc cccataatgt tctttttctt tcactactgt ttgcaaaact tttttgctga
    92701 taagttcttt attcatgaaa aagttcaagt aaggtccgac aacttcgatt ttttcaaagt
    92761 tggcagaatc gattttttct gctaaatctg cagcgatttg ctgtggcgct tttcggtaaa
    92821 cttttgctaa tgaaaaggct ggaaatgcaa catctccgtg ttcagctgat tttggatttt
    92881 ctagtaattg ctcgacttgt tccagtgtta aatcatcttt gacagcgtca tagacagctt
    92941 ttgcgacaag atctttatta ttcatcttta ttcctcctaa agtgttccct tgattgttaa
    93001 acaaaaaaaa tctctagcga cggcatactt agtatgccat cactagagac gagatttccc
    93061 gcggtaccac tccaattgtc ctaaaaaagg accagctcca tctgatatcg gtagacgacc
    93121 gtctgtttaa aacagaattc tccaagtgcg cttcgttgta tcttcttcat tcggcttcca
    93181 ccacttccga attcgctagc caagaatgat acaagtactc tcttgttcaa caaatcttag
    93241 tcttattaaa ctttcttgaa ttatatcaga aaaaaaaacg aaaggctagt cgtttcataa
    93301 aaaaacaatc cagatggcct aaaggagaag aaataccacc tggatagcta taaatcattt
    93361 cgtaaatacg aaagacttaa caaattaatc agctacgata atcgttcctt cttcagaagc
    93421 taaaagattc tcgatatttt ctaaagaagt gatgattgcc ttagcgtttg gttttgcttc
    93481 aacaaatgca atagctgctt ctactttcgg aagcatgctt cctggagcga attgcttttc
    93541 atcaatgtat tgtttcattt ctgaaacagt aacagtttct aatttctttt gatctggttt
    93601 ttggtaattg acatacacat tgtctactcc tgtcaatacg atcagcaaat ccgcatcgat
    93661 gatttcggct aatttttctg aagcaaaatc tttatcgatt acggcttctc gtccttctaa
    93721 tccagtagct gtttctacaa caggaatccc accgccacca acagagactg tgataactcc
    93781 ttgatcgacc agcgtttcga tgacacgtgc ttctttaatc gagatgggtt taggggaagc
    93841 gactactttt ctccatccac gtccagcatc ttctttgaat gtcacagtgg agtcagcatt
    93901 catttgttct ttggcttctt cttccgtgta gaatggaccg actggtttac ttggattttt
    93961 gaatgaagga tcattttcat ccacaataac ttgagtgact aaagaaacca catctttatc
    94021 gatccctttt tccttcagta cttcgcccat ggcgttttgt aaccagtaac cgatagatcc
    94081 ttctgtcatt gcaacacatg tatctaaagg cattgccggt gttttctcag aatcagcagc
    94141 ttgctgctga atcaataggt taccgacttg cggaccattt ccgtgggaga tgatcaattc
    94201 atctccttgt tcgataaatt tcactaaata ctttgctgtt tccattaacg cttcttgttg
    94261 ggcttttgca cttgcatccg tagacaagat ggcattgccc cctaaagcga caactacttt
    94321 tcgtttggcc atttcattcg tcctttcttc agttctaccg aattttctag ataacaaaac
    94381 gagccagcgt tttgtgattt tccctcaatg ctgactcgtt ttttcgtgag atgaatgtgg
    94441 ttatgcttaa acgcgaggga taaacaagtt acctaatgtt gctgccatga tcgctttgat
    94501 tgagtgcata cgattttctg cttggtcaaa ttgacgagca tatttgctgc ggaagacttc
    94561 atctgttact tccatttcag tgatgccaaa gcgttctttc atttgttcac cgtaaacagt
    94621 gtttgtatca tggaaagctg gcaagcagtg caagaagatc aaacgatctg tgttgtgtgt
    94681 tttttctacc atttccatat tgatttggta aggtttcaac aatttgatac gttcttcgaa
    94741 tttatcttct tcacccattg atacccatac atcagaataa aggacgtctg ctccgtctac
    94801 acctttatca acatcgtcgg taatcatcaa ttgtgcaccg gatttttcag caaagccttc
    94861 tgccattttg acgatttctt cttcaggttg taattctttt ggtgcaacga tacgcatatt
    94921 cgctcctaaa attgcacctg tgactaataa agagttagcc atattgtttc gaccatctcc
    94981 gcagtaagca acagtgatac cttctactgt tccaaagttt tcttggatag ttaaaaagtc
    95041 agcgatcatt tgtgttggat gccattcatc agtcaagcca ttccaaactg gaacaccaga
    95101 gaattctgct agttcctcta ccattttttg actgaatcca cggaattcga ttccgtcaaa
    95161 catacgtcct agtactttag ctgtatcttc tgtggattct tttttaccta attggatatc
    95221 atttgcacct agatattcag gatgtgcacc tagatcgatc gctgcagtag taaatgcaga
    95281 acgagtacgt gtagatgttt tttcaaataa aagcgcaata ttttttcctt ctagatagtg
    95341 atgtgggata ccacgttttt tcaagtcttt caagtgttct gaaaaatcga tcaaatattg
    95401 taattcttct tttgtaaagt ctttttctgc taataagctt cttccttgga atactgattc
    95461 tttcatatta aacattctcc tttagattgt ttttatttaa gattaaagag gaaatcccga
    95521 cggcagctga cagtaagact gccgtcagga aacaaattac ttcaagtctt cacggacaag
    95581 tggttggctc atgcagcgtg gaccaccacg acctcgtgac aattcacttg aattgatttc
    95641 taacactttg atgccatagc tacgaagcaa ttcgttcgat acataatttc ggttataagt
    95701 gactacaaca cctggagcga ttgccaatgt gtttgatcca tcattccatt gttctcgagg
    95761 tgcaacgatc tcatctccat taccagttgg gatcagtaca agatcatcta atccaagagc
    95821 agctttcatc gtttcgtgta agttatctga atgagtaatc ttgatatcat caccatctgg
    95881 ttcgattgta aagacatcca tcttaccgtc tttactttga attgctggat ggatagtgaa
    95941 tttatcgtga tctaccattg taaatacggt atccaaatgc atcattgcac ggttgttcgg
    96001 aattttgatt gccaacactt tttcaaatcc tgaatttttt gcgaataggt ggcgtgctaa
    96061 tttttctaaa gctttcgcat tagttcgttg agaaatccca acagctacta ctttatcgct
    96121 taagatcaat tcgtctccgc cttcgatatg atctggattt tcacgatcca accatacttc
    96181 gattccttta tttgcaaatc ttggatgatg tttcaaaata tattctgtaa acatcgattc
    96241 acgacgacgt gcttcaaaag tcatcttatt gactgtcatc ccatttccca ttgatgcgga
    96301 agggtcgcgt gtaaagtaca agtttggcat tgggtccatg taaaatggat agtcatcgtc
    96361 tgctgacaga tcatatagac tgctagaacg tacttcgata tcttttgtac gaaccccagc
    96421 catgatttta tctaccattt cttgcgtttc cattgataga aggaactcat gaagaccctc
    96481 tcttacagca ttcgatgcaa tatgagattc atccaacatt ttattcaaga attgttcttt
    96541 gacattgcct gcgtcaatcg cttctgccgc taatttttcc aagtaaagag tctcgacgcc
    96601 ttcattttgc aatgtcttcg caaagttgtc atgttcttct tgagcaatcg gaagatatgg
    96661 aatatcatcg aacaacagac gatccataat atctggtgtc aaattttcca cttcttgtcc
    96721 aggccgtttc agtaaaactg tctttaattt ccctatttca gagaaaacgt gaataggttt
    96781 atccatgttg tgttgcctcc ttctttttga ttacatgtat aggatatcct ccttttgtaa
    96841 tcactttcat aattttgtct cattcaaaat gagacattcc tcacattaat attcgataat
    96901 taaataatta aacgtttttc tatttttaag cgtaatttat tcat
//
LOCUS       DAFLWQ010000002        91983 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.002, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000002 DAFLWQ010000000
VERSION     DAFLWQ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 91983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 91983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..91983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.002"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..420
                     /locus_tag="L1V16_000083"
     CDS             <1..420
                     /locus_tag="L1V16_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HBN1274456.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(504..1226)
                     /locus_tag="L1V16_000084"
     CDS             complement(504..1226)
                     /locus_tag="L1V16_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBN1274457.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(1216..1953)
                     /locus_tag="L1V16_000085"
     CDS             complement(1216..1953)
                     /locus_tag="L1V16_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1274458.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            complement(1965..2957)
                     /locus_tag="L1V16_000086"
     CDS             complement(1965..2957)
                     /locus_tag="L1V16_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1274459.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            complement(2972..3715)
                     /locus_tag="L1V16_000087"
     CDS             complement(2972..3715)
                     /locus_tag="L1V16_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1274460.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     regulatory      complement(3789..3893)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(3956..5278)
                     /locus_tag="L1V16_000088"
     CDS             complement(3956..5278)
                     /locus_tag="L1V16_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1274461.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     gene            complement(5265..6230)
                     /locus_tag="L1V16_000089"
     CDS             complement(5265..6230)
                     /locus_tag="L1V16_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1274462.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            complement(6227..7765)
                     /locus_tag="L1V16_000090"
     CDS             complement(6227..7765)
                     /locus_tag="L1V16_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HBN1274463.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            complement(8181..8468)
                     /locus_tag="L1V16_000091"
     CDS             complement(8181..8468)
                     /locus_tag="L1V16_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274464.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            8602..9270
                     /locus_tag="L1V16_000092"
     CDS             8602..9270
                     /locus_tag="L1V16_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1274465.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            complement(9561..10301)
                     /locus_tag="L1V16_000093"
     CDS             complement(9561..10301)
                     /locus_tag="L1V16_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274466.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(10431..11378)
                     /locus_tag="L1V16_000094"
     CDS             complement(10431..11378)
                     /locus_tag="L1V16_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1274467.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(11507..12271)
                     /locus_tag="L1V16_000095"
     CDS             complement(11507..12271)
                     /locus_tag="L1V16_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBN1274468.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            complement(12275..12664)
                     /locus_tag="L1V16_000096"
     CDS             complement(12275..12664)
                     /locus_tag="L1V16_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274469.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            12799..13341
                     /locus_tag="L1V16_000097"
     CDS             12799..13341
                     /locus_tag="L1V16_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HBN1274470.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            13489..14121
                     /locus_tag="L1V16_000098"
     CDS             13489..14121
                     /locus_tag="L1V16_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274471.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(14255..14380)
                     /locus_tag="L1V16_000099"
     CDS             complement(14255..14380)
                     /locus_tag="L1V16_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1274472.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(14514..15407)
                     /locus_tag="L1V16_000100"
     CDS             complement(14514..15407)
                     /locus_tag="L1V16_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HBN1274473.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(15589..16515)
                     /locus_tag="L1V16_000101"
     CDS             complement(15589..16515)
                     /locus_tag="L1V16_000101"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HBN1274474.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(16600..17361)
                     /gene="pflA"
                     /locus_tag="L1V16_000102"
     CDS             complement(16600..17361)
                     /gene="pflA"
                     /locus_tag="L1V16_000102"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBN1274475.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(17605..19836)
                     /gene="pflB"
                     /locus_tag="L1V16_000103"
     CDS             complement(17605..19836)
                     /gene="pflB"
                     /locus_tag="L1V16_000103"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBN1274476.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(20113..22563)
                     /gene="parC"
                     /locus_tag="L1V16_000104"
     CDS             complement(20113..22563)
                     /gene="parC"
                     /locus_tag="L1V16_000104"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBN1274477.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(22575..24620)
                     /gene="parE"
                     /locus_tag="L1V16_000105"
     CDS             complement(22575..24620)
                     /gene="parE"
                     /locus_tag="L1V16_000105"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBN1274478.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(24786..25220)
                     /locus_tag="L1V16_000106"
     CDS             complement(24786..25220)
                     /locus_tag="L1V16_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBN1274479.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            25347..25985
                     /gene="plsY"
                     /locus_tag="L1V16_000107"
     CDS             25347..25985
                     /gene="plsY"
                     /locus_tag="L1V16_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBN1274480.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(26117..26992)
                     /locus_tag="L1V16_000108"
     CDS             complement(26117..26992)
                     /locus_tag="L1V16_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBN1274481.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(27074..27865)
                     /gene="codY"
                     /locus_tag="L1V16_000109"
     CDS             complement(27074..27865)
                     /gene="codY"
                     /locus_tag="L1V16_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBN1274482.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(27883..29283)
                     /gene="hslU"
                     /locus_tag="L1V16_000110"
     CDS             complement(27883..29283)
                     /gene="hslU"
                     /locus_tag="L1V16_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HBN1274483.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(29297..29845)
                     /gene="hslV"
                     /locus_tag="L1V16_000111"
     CDS             complement(29297..29845)
                     /gene="hslV"
                     /locus_tag="L1V16_000111"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HBN1274484.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(29882..30787)
                     /gene="xerC"
                     /locus_tag="L1V16_000112"
     CDS             complement(29882..30787)
                     /gene="xerC"
                     /locus_tag="L1V16_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBN1274485.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(30985..32361)
                     /gene="trmFO"
                     /locus_tag="L1V16_000113"
     CDS             complement(30985..32361)
                     /gene="trmFO"
                     /locus_tag="L1V16_000113"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HBN1274486.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(32330..34408)
                     /gene="topA"
                     /locus_tag="L1V16_000114"
     CDS             complement(32330..34408)
                     /gene="topA"
                     /locus_tag="L1V16_000114"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBN1274487.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(34530..35387)
                     /gene="dprA"
                     /locus_tag="L1V16_000115"
     CDS             complement(34530..35387)
                     /gene="dprA"
                     /locus_tag="L1V16_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBN1274488.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(35443..36210)
                     /locus_tag="L1V16_000116"
     CDS             complement(35443..36210)
                     /locus_tag="L1V16_000116"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBN1274489.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(36203..37063)
                     /gene="ylqF"
                     /locus_tag="L1V16_000117"
     CDS             complement(36203..37063)
                     /gene="ylqF"
                     /locus_tag="L1V16_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBN1274490.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            37323..37721
                     /locus_tag="L1V16_000118"
     CDS             37323..37721
                     /locus_tag="L1V16_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1274491.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            38000..38500
                     /locus_tag="L1V16_000119"
     CDS             38000..38500
                     /locus_tag="L1V16_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBN1274492.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(38583..39134)
                     /gene="lepB"
                     /locus_tag="L1V16_000120"
     CDS             complement(38583..39134)
                     /gene="lepB"
                     /locus_tag="L1V16_000120"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBN1274493.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(39286..39513)
                     /locus_tag="L1V16_000121"
     CDS             complement(39286..39513)
                     /locus_tag="L1V16_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBN1274494.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(39510..40028)
                     /gene="msrA"
                     /locus_tag="L1V16_000122"
     CDS             complement(39510..40028)
                     /gene="msrA"
                     /locus_tag="L1V16_000122"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBN1274495.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(40048..40761)
                     /locus_tag="L1V16_000123"
     CDS             complement(40048..40761)
                     /locus_tag="L1V16_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBN1274496.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(40764..41660)
                     /locus_tag="L1V16_000124"
     CDS             complement(40764..41660)
                     /locus_tag="L1V16_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBN1274497.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(41818..42660)
                     /locus_tag="L1V16_000125"
     CDS             complement(41818..42660)
                     /locus_tag="L1V16_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBN1274498.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            42792..43445
                     /locus_tag="L1V16_000126"
     CDS             42792..43445
                     /locus_tag="L1V16_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBN1274499.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(43508..44035)
                     /locus_tag="L1V16_000127"
     CDS             complement(43508..44035)
                     /locus_tag="L1V16_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBN1274500.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(44055..45002)
                     /locus_tag="L1V16_000128"
     CDS             complement(44055..45002)
                     /locus_tag="L1V16_000128"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBN1274501.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(45014..46900)
                     /locus_tag="L1V16_000129"
     CDS             complement(45014..46900)
                     /locus_tag="L1V16_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBN1274502.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(47060..49138)
                     /locus_tag="L1V16_000130"
     CDS             complement(47060..49138)
                     /locus_tag="L1V16_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBN1274503.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(49151..49426)
                     /locus_tag="L1V16_000131"
     CDS             complement(49151..49426)
                     /locus_tag="L1V16_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274504.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(49788..50243)
                     /locus_tag="L1V16_000132"
     CDS             complement(49788..50243)
                     /locus_tag="L1V16_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274505.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(50397..51605)
                     /locus_tag="L1V16_000133"
     CDS             complement(50397..51605)
                     /locus_tag="L1V16_000133"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBN1274506.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(51717..52049)
                     /locus_tag="L1V16_000134"
     CDS             complement(51717..52049)
                     /locus_tag="L1V16_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBN1274507.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            52197..53072
                     /locus_tag="L1V16_000135"
     CDS             52197..53072
                     /locus_tag="L1V16_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1274508.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(53154..53735)
                     /locus_tag="L1V16_000136"
     CDS             complement(53154..53735)
                     /locus_tag="L1V16_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HBN1274509.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(53741..55000)
                     /locus_tag="L1V16_000137"
     CDS             complement(53741..55000)
                     /locus_tag="L1V16_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBN1274510.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(55002..56048)
                     /locus_tag="L1V16_000138"
     CDS             complement(55002..56048)
                     /locus_tag="L1V16_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274511.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(56283..56558)
                     /locus_tag="L1V16_000139"
     CDS             complement(56283..56558)
                     /locus_tag="L1V16_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBN1274512.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(56801..58111)
                     /gene="der"
                     /locus_tag="L1V16_000140"
     CDS             complement(56801..58111)
                     /gene="der"
                     /locus_tag="L1V16_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBN1274513.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(58293..59522)
                     /gene="rpsA"
                     /locus_tag="L1V16_000141"
     CDS             complement(58293..59522)
                     /gene="rpsA"
                     /locus_tag="L1V16_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBN1274514.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(59657..60337)
                     /locus_tag="L1V16_000142"
     CDS             complement(59657..60337)
                     /locus_tag="L1V16_000142"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBN1274515.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(60386..61021)
                     /locus_tag="L1V16_000143"
     CDS             complement(60386..61021)
                     /locus_tag="L1V16_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBN1274516.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(61087..62490)
                     /locus_tag="L1V16_000144"
     CDS             complement(61087..62490)
                     /locus_tag="L1V16_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBN1274517.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(62477..63508)
                     /locus_tag="L1V16_000145"
     CDS             complement(62477..63508)
                     /locus_tag="L1V16_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1274518.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            63539..63760
                     /locus_tag="L1V16_000146"
     CDS             63539..63760
                     /locus_tag="L1V16_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBN1274519.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(63925..64662)
                     /locus_tag="L1V16_000147"
     CDS             complement(63925..64662)
                     /locus_tag="L1V16_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HBN1274520.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(64815..66155)
                     /locus_tag="L1V16_000148"
     CDS             complement(64815..66155)
                     /locus_tag="L1V16_000148"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBN1274521.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(66392..67915)
                     /locus_tag="L1V16_000149"
     CDS             complement(66392..67915)
                     /locus_tag="L1V16_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBN1274522.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(68293..68904)
                     /locus_tag="L1V16_000150"
     CDS             complement(68293..68904)
                     /locus_tag="L1V16_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBN1274523.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(69027..69152)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(69234..69950)
                     /locus_tag="L1V16_000151"
     CDS             complement(69234..69950)
                     /locus_tag="L1V16_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBN1274524.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(69956..70525)
                     /gene="scpB"
                     /locus_tag="L1V16_000152"
     CDS             complement(69956..70525)
                     /gene="scpB"
                     /locus_tag="L1V16_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBN1274525.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(70509..71306)
                     /locus_tag="L1V16_000153"
     CDS             complement(70509..71306)
                     /locus_tag="L1V16_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBN1274526.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(71276..71647)
                     /locus_tag="L1V16_000154"
     CDS             complement(71276..71647)
                     /locus_tag="L1V16_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBN1274527.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(71666..72553)
                     /gene="xerD"
                     /locus_tag="L1V16_000155"
     CDS             complement(71666..72553)
                     /gene="xerD"
                     /locus_tag="L1V16_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBN1274528.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(72649..73122)
                     /locus_tag="L1V16_000156"
     CDS             complement(72649..73122)
                     /locus_tag="L1V16_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBN1274529.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(73227..74090)
                     /locus_tag="L1V16_000157"
     CDS             complement(73227..74090)
                     /locus_tag="L1V16_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBN1274530.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(74286..76385)
                     /locus_tag="L1V16_000158"
     CDS             complement(74286..76385)
                     /locus_tag="L1V16_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBN1274531.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(76605..77714)
                     /gene="rpoD"
                     /locus_tag="L1V16_000159"
     CDS             complement(76605..77714)
                     /gene="rpoD"
                     /locus_tag="L1V16_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBN1274532.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(77738..79579)
                     /locus_tag="L1V16_000160"
     CDS             complement(77738..79579)
                     /locus_tag="L1V16_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBN1274533.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(79761..82076)
                     /locus_tag="L1V16_000161"
     CDS             complement(79761..82076)
                     /locus_tag="L1V16_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBN1274534.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(82261..83121)
                     /locus_tag="L1V16_000162"
     CDS             complement(82261..83121)
                     /locus_tag="L1V16_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HBN1274535.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(83180..83701)
                     /locus_tag="L1V16_000163"
     CDS             complement(83180..83701)
                     /locus_tag="L1V16_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBN1274536.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            83979..84740
                     /locus_tag="L1V16_000164"
     CDS             83979..84740
                     /locus_tag="L1V16_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1274537.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            84766..87357
                     /gene="mprF"
                     /locus_tag="L1V16_000165"
     CDS             84766..87357
                     /gene="mprF"
                     /locus_tag="L1V16_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBN1274538.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(87545..88732)
                     /gene="tuf"
                     /locus_tag="L1V16_000166"
     CDS             complement(87545..88732)
                     /gene="tuf"
                     /locus_tag="L1V16_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBN1274539.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            89100..89456
                     /locus_tag="L1V16_000167"
     CDS             89100..89456
                     /locus_tag="L1V16_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBN1274540.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(89697..90701)
                     /locus_tag="L1V16_000168"
     CDS             complement(89697..90701)
                     /locus_tag="L1V16_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBN1274541.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            90867..91718
                     /locus_tag="L1V16_000169"
     CDS             90867..91718
                     /locus_tag="L1V16_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBN1274542.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            91735..91980
                     /locus_tag="L1V16_000170"
     CDS             91735..91980
                     /locus_tag="L1V16_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274543.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
BASE COUNT        25453 a        19316 c        15779 g        31435 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacaac ctgttgtaca agaaacggtt
      121 caaacggaaa aacaagcagc gcctgttgct gaaacacaac ctgctcctgc tgtaacagaa
      181 actgctgcta ctccagcaag cacaagctct gcaaaagaat ggatcgcaca aaaagaatca
      241 agcggttctt acacagcaac gaacggacgt tacatcggac gttaccaatt agattcttct
      301 tacttaaatg gtgactactc tgctgcaaac caagaaagag tagcagaaca atatgttact
      361 tcacgttatg gttcttggga agcggcgaaa gcattctggg aagcaaacgg ttggtactaa
      421 gattcattta ttaatcaaac agtttacttt tatacaaaga aagccaaaaa gaggtgcgac
      481 actagttgtg tcacatctct tttttattta cctaatctaa tgaaacgttc caagttttga
      541 taagtatttt ttttaacttc ttcaactgat agctctttga tctcagcgat tgtctttaac
      601 tgttcttcaa gcagtgagac ataatctttt tctgaaaaaa tcccccctaa agcccactct
      661 gctgcatgta gtccatccgt ttcaataagt aagtggtcga ttgggactgc tttagctagt
      721 tgccagactg ctggattctt tttcaaatca agaccaatgc tgaaataaca gcctaaatca
      781 atatagtctt gttgatagtc caaagaagaa taccaatgga tcaaatagtg attagggtaa
      841 gcttggatat aatttaagat ctctttttcg catccttttg tgtgcagtac aacaggtttc
      901 tcatttatgg ctgcaaaagc aagctgtcgc tcaaatactt ttttttgtgt agtcatcggt
      961 acattcgtcc aaatattatc taaccctatt tcaccgatga tccttgcttt tttcaaaaaa
     1021 ggctcaactt gttcaaacgt atagctatct gctttccaag gatggatacc gtaacttaag
     1081 gcttgagtct tacttgctgc aagctgtctg ttttccttcc attcttctgg cgaatcacaa
     1141 ttgatgatcg tcaaaatcgt gtgttcctgc tgaaggagtg ctaaactctg actcccatct
     1201 aaatgacaat gagcatcact taacatctaa ttcacctgcc aataactgat aaatcgtttg
     1261 cttcaactct gattgctgca gtagccattc acgtgaccgt cgtttttcag gcacttgaat
     1321 ctcagcaatc acatgtgccg gacgggcgga aagcacaaga atcctgtctg ataaataaat
     1381 tgcttcttcg atatcatgcg tcacaagtaa agtagtccgc tttgcttttt taggcagctt
     1441 caacatccag tcttgcatct gccctctggt catagcatct aacgctccaa atggttcatc
     1501 aagaagcaag taagaagaag gattcatgat tgttcgtaac aaggccgttc gctgcttcat
     1561 cccgccagat aattgttccg gcaaaaaatg ttcatagccg tttaacccaa agatatccag
     1621 ataatccctt acttgttctt cattgattgt tagatgattg attttttgat ataacgtaac
     1681 gttttgatag acgctcagcc aaggaagtaa catatcttct tgcggcatat aactaaatgc
     1741 tgtatggaga ccagttactt tttgatcgtc tactttgatc gttccagaag tcataggctg
     1801 gactcctgtt aaagttttca gcaatgttga cttaccggct ccgcttggcg cgacaatcga
     1861 tgtaaaggta tctttaggga tagtgaaatg gatgtcttct aatattttca ggttttcaat
     1921 gactacattc aagtggctga tttggattga catatctatc actcctattt tataaactga
     1981 ttagtgaata gttcttgcga aggtacatct tgcttgatca atccgttttc ctgcataaaa
     2041 gctgtataat tgcgccaaac tttttcttcc atcaatcccc aattctcagg atcatccgta
     2101 taattttttg acaagaatgc ttgtgattct tctaaaaacg tccgatcatt ttcttttgca
     2161 tatttttgca acagtttagc actgtcattt ggatccttaa tagcttcctg atagcctttt
     2221 ttcgtggcat ccataaaaga ctgtaccaat tctggatcac ttttgatcag ttgatcattc
     2281 gtaataatta ccggagtata gtaatctaac cgttcatcta attctttcaa tgggatatag
     2341 tttagttcaa tacccgcttc ttttgctttg atcatatccc aaccttcaaa gtaccattgg
     2401 atatctgagg attttcctaa gctttctggc ccttctccat tgcttcctac cattgtcagt
     2461 tttgaaaagt ccccgccgtc tttttccatc acagctttta agacagcttc ttcacttgga
     2521 ctttgccaac ctgcatatgt ttttccttca aaatcttttg gtgaatggat gttactgtct
     2581 gatagggtgg cgaatccaga agtattatgt ttgatcactg tagcaattgc tttgactggt
     2641 atattctgtc catctgcgtg agcataagtg acatcttctt gataacttac accaaattgt
     2701 gctttgtccg cacctactag accaatactt gtcgaattat ctcctggttc gatgatttgg
     2761 acatttaaac cagcctcttt ataatagcct ttttcttttg ctaggtagat gccagtatga
     2821 ttagtattcg gtacataatc caaaacaagt gtcacttttt tcaaatcctt tatttcttgt
     2881 ttgctacttg tttcttttgc agtgccacaa gcggataaaa gcaacagtag cggtaataaa
     2941 agccataatt ttttcatttg atccccttct cttaaaaaat ataaagcata cgataatacc
     3001 cttttttcaa taatgaacaa gcgccattca gcaataaact caatagaatg acacaaatga
     3061 tcgcagcaaa aactttatcg atctggtagc tgttttttac gcgtatcatg taatacccta
     3121 agcctgcttg agcgcttagc cattctccaa cgactgctcc gctgacacaa taagtagcag
     3181 ccacttttaa accggaaaag aagccggata aacccgctgg tattttatat attcgataaa
     3241 tcttccctgt atctgccccc atcgttttca aaaagatgat ttgctctttt gatactttcc
     3301 tcaatgtatc cgaaaaagaa actacgatcg gaaaatagct tatcaagaca acaaggatca
     3361 cttttggaag cataccgaaa ccaaaccata gggtaagtaa tggccctaac accatgattg
     3421 gcaacatttg tgaaatcact agtaacggat aaaaagacat ttctaaaaac ttccaataat
     3481 ccattgccaa ggcagtaata aaagaaagaa cgctagctat taccaaacca agcactgctt
     3541 catttaatgt cgtgacagaa tgggaaagta atacttgtgc atctgccgct aatgcagaaa
     3601 atacagcagc aggtccgggt aaaataaagg caggtatttt ccaaactatg acaacaatct
     3661 gccaaataat taaaatgaat gccatactga ctgctggata aagatttttc ttcattttgt
     3721 tacctccttt cttctaatat gaataacaaa aaacgcttga aatgggcacg acatagtaac
     3781 ccgcttcaag cgtctgctat gtttctccct tcaccagtat taactgacag gttcaatggg
     3841 tctaagttca caacttactc tcatgtcgtc tacgacatcc ccagaaacag gtattcattt
     3901 tttaaagtgt agcacaagaa ggaaaaagca acaagcgctt tagttatcat gctgattatt
     3961 tcaataaata ggagagatca cttgccaatg tcggataccc catgatatag ctatccaact
     4021 cttttttagt caatttttga ttgatgacga gtgtcaaatc atcgatcaat tcgtctgctt
     4081 gctcgctaat cactgcagca ccaatcaaat aattttgctg gtcaaaggtc aattcagcct
     4141 tagcaactgg ttcattgaca cgatgatagg tgaaccaact ggtaagatcc atctctacca
     4201 cttgatctga cgaagaggcg tgactttttg taactcctac ttcagcaagt ttaggactgg
     4261 cgtagacgat cgtaggtata atcggatatt tgataggttc gcttgttgca tccgttatcc
     4321 gcttagctac ataatttcct tcaaaagtgg cgactggtgt caattttggg gttttccttg
     4381 aaacaatatc tccacacgca aaaatttttg gattgctcgt ttgcagataa tcattgactg
     4441 caattccgtg tttatcaaag acgatattcg cttgctcaag tgctaaagat tctgtattcg
     4501 gctgtctccc agtcgcacaa aaaatcatat ctgctactaa ttccgtctct tttccgacta
     4561 aacgatagcg agtaccttct gaaatgatct tttgggtttc aacaccaaaa gcaaactgaa
     4621 tgccagatgc ttccatttga tggacggctt cctctaccaa agacgcctca aattctttta
     4681 atggccgttg attatgatgg acaatggtta ctttgctccc tgcagcattg gcaatcgtag
     4741 ctagctcaaa agcaatataa ccaccaccga taaaaatgat ttctttaggc agtacaggca
     4801 atgataaaaa gtctgcacta gttttcaagt attcctttcc ctccactggt aagatcgtag
     4861 gtctttgccc ggttgccaaa actaagtaat ccgcatggaa gacttcttcg ttgacttcaa
     4921 tagatgaatc atccaaaaaa cgagcggttc ctgaaagatg atcgatttca gcttctgcta
     4981 attgtttttt tcggctttct gggactggat ccgtaaatgt tcgtttgaat ttttgaagtt
     5041 cttcccagtt ggcagttggg atctcgttaa aaccttttcc actcaattgt tttacccgat
     5101 tacgtgcctc tactgcactt aacaagactt ttttaggatc acatccacgg ttaggacaag
     5161 tcccgcccca tagatcttct tcgaccacta gtactgtttt acctgcttct ttcaatccat
     5221 aagcagcact taagccgctc acacctgaac cgatgatgat tgcatcatat gttttcattt
     5281 ccttcctcct ctcgacttaa aaaagcaaag atttctttac ttgtcagcga cccaatactt
     5341 ctttgctttt ctactatcac aatgcttgga tacaccgaaa gaagcgaata tacttctttc
     5401 ataggcgtat caaagcaaac ttgttgacga gcattttctg gtatttcatt taagaaatat
     5461 ccattgacga ctaaatcttc tactcgccac tctttcgtct gtttcggttc atcaaagaaa
     5521 tgccgaacgt agtcgttttt aggattcatc aataactgct ctggtgtgtc acattggata
     5581 atttctccat ccttcataaa tgcaatacga tcacctagct tgattgcttc ttccatattg
     5641 tgcgtaacga aaacgatggt cgtgcccaat tcttcgtgta aggacaaaac caattcttgt
     5701 aatgagtttc ttgaaatcgg atctaatgcg ctaaatggct cgtccatcaa aatcacatct
     5761 gggcttgcag caatagctcg gatgatcccg atccgttgct gttctcctcc agacaactct
     5821 ctaggcatac gatctcgata aatatcagga gataagccaa ctttttgaag aagttcatct
     5881 acacggtctg ctcttttctg cttttcccaa cctaacattt cagggatgac ttcaatattt
     5941 tgcttgactg tcatggtcgg gaacaaagcg atttgctgca gcacatatcc catattccac
     6001 cgcattttct gcagattata ttcatttaac gattttcctt tgaagtagat gtctcctgct
     6061 gatggtttag ataatccatt gatcattttc aaagtagttg tttttccact accggaagga
     6121 ccaaccaaaa caaagatttc tccttttttg attgccagat ttaggtcatc gatgacatac
     6181 tttccatcat actttttttg cacatgtttg aactcgatta atttagtcac tgatcttcct
     6241 cctttactaa tccttcattt ttcaggaaga ttcgtgctac ttctgtcggc tttttctttt
     6301 cgacattgac ttggtaattc atatcaatca tttgatcctc tgttattttt ccgcttaatt
     6361 tattcagtgc tttaacgatt tcaggatgtt ctttagcaaa atcttttttc atcagcggtg
     6421 cgccttgata agctgggaat aaccctcgat catcttctag agtcactaga tcgtactcct
     6481 tgagctggct atctgtggaa taggcatcca caatattgac atctccatta ttgattgctt
     6541 ggtaacgcaa acttggctcc atgctttgta cacttgaaaa attcaagcca tatgcttctt
     6601 ggattccttt atatccatct gaacgatcaa taaattccag tgtgaatccc gctttgatct
     6661 gatcagagat agctgccaaa tcggaaatct ttttaagttg atgttcgttc gcaaaagatc
     6721 tcttgactgc caaggcatac gtattttggt aagccattgg ttttaataat gtcatatcga
     6781 attgcttatt caataattct tctgcttcgt catatgtttt ttcttttgtc aaatcagcac
     6841 ttttcattgc ttcaggtacc ttcaccaagc tttctaggac agtacctgtg aactcaggat
     6901 agatatcgat ttgaccttga tccagtgcat tgaacaaaaa actcgtcttg ccaaaattcg
     6961 gttttaattc aacttctgtt tttgtgttgt cttcaatcaa ttctttatac atttggatca
     7021 ggatttcagg ttccgctcct aattttccag caatcgtgat ggtttcattt ttaaacaagg
     7081 cagactgata taaagaaacg ccgccaaata aacacaccac tgctgctaaa gtaatgatgg
     7141 aatatcgagg tttcttatgc tgcaaccagc gaatcagtcc gctgaatata attgcaagca
     7201 aggcagaact gatcgcacca atcaatgtca aaacaggtgt atttcggtca atacctaaca
     7261 aaataaatgt ccctaatcca cctgctccga tcaatgctgc caaagtagcc gtaccgatga
     7321 ttaaaactaa ggcagttcgg atacctgaga taatgacagg taatgcgatg ggaagctcta
     7381 ctttcagcaa gcgtctcatt ctggacatac caaatgctac cgctgcttct tcaatagacg
     7441 ggtcaatttc agctagacca atatacgtgt tttggaaaat cggaagcaaa gcgtaaataa
     7501 caagtgcaat caatgctgga acagttccga tccctacaaa tgggataagt aaacctaata
     7561 aggcaagtga aggaatcgtt tggagcacac ccgtgatctg caataagact tctgccattt
     7621 ttttatgatt ggctgcccaa atcgctaaag gaatagcaat cagtgctgca atcagcaaag
     7681 aaatgagaga aatggacaga tgttgaaatg cagcttccag caactcgcct tttctttcac
     7741 ttaatgtttg tataaaatta ttcatgcgac cttcctttct gttattcttt aagtataaac
     7801 atttctttcc tttttcccaa ctaacttgtc ttgccttaac cttacagcac gaacaaaaaa
     7861 aagaaaaaaa tacctctaaa tatgctgaca aaaaaagaat ccaagcaaca aagtcggatc
     7921 aactttttgg ttctcgtttt ttcactacga ataccataaa aatctatacg aaattgtcac
     7981 ttggaatcag ctatatcttt tttacacaca caacttttat tttaataaaa agaaacagcc
     8041 aataaagtag aaatctcgtg ggggagaaca cctttattgg cctgttcaac gaatattata
     8101 ctgtatcatg acactttttt gccaaaaatg taaaaaatgg ttgttttgac atcataaacg
     8161 tcttgttttc ttatttttac ttatatcacc actttatttt ctatctcttt cactccataa
     8221 agaggaatga gttcttcttt tgactgataa taaacagctt tctcacggtt cttcatcaaa
     8281 aaaagaaaga tgtctttcat agcaagtggt gctttgccgt gttcaaataa aaagataaat
     8341 tgatttgctt tatttatctg gaccattgtc acaggcacca gtttttgttc ttgagccaaa
     8401 aaaactcctt gatactctgt ttttttgggt gattttgtaa gaattgtcaa taagtctgct
     8461 gctcgcattt ttccactcct tatttgataa ataaaaagaa acagccaaaa ataatttttt
     8521 ttcattttcc tcttgaagta agagtataag tcagtataat aaagaagttg ctgaaaattt
     8581 tcaaaagaaa agaggctaga aatgaaaaaa ttaaatttat ttacagaatt gtgcggaatc
     8641 attttaggcg caggaatcta cggattagct gtgacaggaa tcaatattcc atctaagctg
     8701 gcagatggtg gggttactgg tattgctttg cttttgcata atctttttgg attcgctcct
     8761 tctgtcactt cactgctttt taatttacct ttattgctta tctcattgtt tctttttgga
     8821 aaacacgctt ttctccggac gatcgtcgga acatttgcgc tagttttctt tttacattta
     8881 tgggagagcc ttcatataca ttttgctgta gatagtctac tgatcaatag tttgatgaca
     8941 ggtattcttt ctggcattgg ttgcggtctc gtctttcgat tcggcggaag cacaggcgga
     9001 acagatatca tttatcaagc cattgaaaaa tattttcata ttaagattgg caaaagtctt
     9061 ttcttgatta cttttggtat tttagttgtc tccttgcttt atttggatct cacacatttt
     9121 ctgtatacat tacttagctg ttctattcta tcttatacat tgaataaagt gaagtatctg
     9181 gaaattggat ctgttttgcc ccaattggaa gcaaaacaga ctacagaaac atttgaacca
     9241 cttgatcctc ttgaacagtt agagcactga ttcttatttt tcactacttt atttaattta
     9301 cagaaatatc attatgtaaa ctaaaatgat attattcagt aaaatcttct ttataaaaaa
     9361 ataaactatt tttgcaaacg atctgcgaaa atagtttgtt tttttatttt gccattattt
     9421 tcttacttat tgggagaaaa aattcgctta aactcaaaaa aatttgagga tacgatataa
     9481 actttcggat agagtataaa ataaggaaac gccgcagcgt ttcctttcca actgtagccg
     9541 aatataaatt tgtatatcac ttatttaaaa tagctatttt ctcccaaaga gtttccttga
     9601 tcatcgatca atccttgtaa tgagcgttct aagataccat ggcttttttt cgattttttt
     9661 tcttctgact gctttgtttc ctctaacgtt tttgttcgat tgaatgttcg tacagacggc
     9721 tcaccatttc ttttttcttg atacggcgtc ggttctgtat cgaacaacag ataagagtca
     9781 tccgtttttt tcatcgattc gattaaatga tcctcagaaa ttttgctttc tctagggtct
     9841 gggataatcg atgcgggtac atatttagga acaaaataag aacgctcccg caccttcgtg
     9901 tcaacagatg cgtttcgtgt agtatgcttg gactctgtcc ttgtttcact ttgtctgaca
     9961 gaacgagagg aatcaccaaa aagttttttt cgtcctgtcg atgtgatttc tgattggtaa
    10021 tggccggtat aatccggtaa ttttccttta tgcttttcca aattttcctt acgcggagct
    10081 gacttcaatc catttgttgc acgacgcttg cgacggattt tctcggtgtt cgtgttcgtg
    10141 aaatgaaatt ctttcatctg ttcaaacggg gactgattct gttcagtcaa aagatcttct
    10201 tgtccgtcaa ataatactcg cttcttgtcg ttggttaatt ttacgcctaa ctcatcatcg
    10261 tacgcaggaa aacggaaatg ttttcgtctg atttctttca ttcaaaccat ccttctcaaa
    10321 aatggaactt ttctcaataa tagcacagat tcattgtttt cagtagcaat gcgctgatta
    10381 ttttaagaaa atagcgatga atttcataaa tatatatata gtaataagac ttaattcgtt
    10441 gtctctctga taactagttc aggaaaaaaa cgacgataac cttgactcgc ccctttttct
    10501 tctatttttt ttaacaacat ttctccacat acttcaccca tacgtataat atcttgcttg
    10561 atcgttgtca atttaggtga actgatttgg tctaaaaata ccccatcaaa tccaatcaca
    10621 ccaaattctt cgggcaagtg tcctccagca tttataatcc ctcttactgc tcctagtgct
    10681 agccgatctg aactacatac aaaacaagtt ttatctgtaa aatctgccca gttttctgtc
    10741 atatatcttt ctacttctgt cgaatgattt ggaaaccgca agattttact aggaagatca
    10801 acttccttca tcacagataa ataaccagtt tcccttgaaa tttcaaaagg ctcgtccact
    10861 tcgataccga tataaataat cgtttgataa tctctttcta aggcatattg cgttgctttt
    10921 gctgtaccat attcattatc gctgtctaca taatcatatc cttcagaatt ttccccaaac
    10981 aagacaactg gtttttccaa acggtcgatc caatcgaagt ctttttttct gacacctgtg
    11041 atgatgtatc catcacaaga accgacgtcg aaggcatcat ttgtaactaa ttggagagaa
    11101 taatgcgctt taccgatccg tttagcgatt cccatcagca aattcatgta atagggctca
    11161 gttgtgtcga tttcttccag tataaataat ttgatgatct gcgaccgatt cgtgacaagt
    11221 gcttttgcag caatatttgg acggtaatcc agttcagcca ttgctgagaa aactaactct
    11281 ttcaattcgt cagtcacctg ttccggatga ttgatgactc gagagaccgt catttttgaa
    11341 acattggcac gttttgcaac atctgctaaa gtgggcatgc tctcttcctt tctaacatgt
    11401 tgtcattctt actatcaatt ataccaaatt ttcctaacag agtttattat agcccaaaat
    11461 aaaaaacgga aaatcctcta tcgtcatgag tgattttccg tttcaattat ttatactttt
    11521 ttatcaaatt ttttgctaaa aaagtggaag cttcttccat tagtggtatt tgtaccatat
    11581 gtcgctgtgt ttttgaggaa cgaaaaacaa tttcttttcc gtaagactta tgccgatttt
    11641 tttctacaaa tcgttccgtt tgtatataag ggattttttc gtcagcttgt ccatgccaaa
    11701 agaacagagg acgtccagct aacttttccg gctgcaatga caaatcatag ctcttaaccc
    11761 atgaaatcaa atcaaaatag tcttttggta cgacataatt atattccgat gcgcgcctta
    11821 cgatttcttt tccatattcc aaaggtgcag gggaacccat caaacacacg cccgctacta
    11881 tatgaggatg tttagccaac aaggcgcatg ttgtcattcc ccccatcgaa accccgccaa
    11941 ctgcaagctg atcatgtaga agacctcttt tttctaaatg cttgataagt gtgtcaaatt
    12001 caaacagatt tccgtagata ctatcccaaa atgtatagga tggaatagaa gaaaccggct
    12061 gtttgcgctc cccatgattc atcgcatctg gcaggatcac acgaatgccc tgctgcgcaa
    12121 tttttcttcc ttgcgtcaaa actaactcct tacttgtctg ccatccgtga taatagatga
    12181 caacgggaat acgttcctct cttaattctt tcagaacaac ttctaacact ggaatatgat
    12241 ggacagaacg tttcaatata attggattca attgttactc acctattttc attaaatttc
    12301 ctgatcgcca tagcaaccat gctccaacag ttgtctggaa caggttcagt gtaccaaata
    12361 atataaatgc aggactgaat ggctcgggaa ataagcacag agaacaaagt cccaccactc
    12421 ctaatgctag cgaaaggagt ggataaatag aaaaattcaa aaaactggca acgctaccga
    12481 aaatattacc aataaacagt atcaaaaaga aaaaaacgct taaaattaaa ccatctgtca
    12541 gcgacatctg aaaaacaatg ttctctacct caattggctg ttgaatcgaa tagacaccta
    12601 agtatatact gagaaggaga cttagcacgt ggctggcaca aaacacacga ttgaccgttt
    12661 tcattttaat cacctaacct atctttataa ttctattata atcattttat catttttttg
    12721 tatgtataaa gtttcaattt ttcttcactt acgatttttt ttgatattgt tgttatataa
    12781 atgaaaggag ttttacaaat gattgatcca aaaatgttgg ggatgatctt cctcattaat
    12841 tttgcttata tcactctgaa cacgttacgt ttcatgttga caatgaaagg ctatcgactg
    12901 attgctccac ttgtcagtat ggtcgagatc acgatttata tcgtcggctt atcccttgtt
    12961 ttagatcgtt tagataatcc actgaattta tttgtctatg cgttaggtta cgcagtaggt
    13021 atcagtgtcg gaattttgat tgaagacaaa ttggcattag gatacatcat ggtcacaacg
    13081 attttgccag caaatagcgc agaagataaa agtttgccgg gtatactgag agaacacggt
    13141 tatggtgtga cacagacttc tgcaatgggg ctggaaggtg agcggctagt tctcgaaata
    13201 ctttctccta gaaaaagcga acgtgaactg tatcgcctga tcaaagaaat cgaagagcgt
    13261 gcttttatca tttcttatga gccaaaatat atttcaggtg gtttctggac taaaaaagtg
    13321 agaaaacgac aaggaaaata actcacaaac ttaaaaactg tctaatatct aaattaaatt
    13381 ttaaatgtta gacagttttt atttattatt ttgattaaaa aacatcgaca tatactcatc
    13441 aatttgttat tatactttat atacttatca atttaatttg gagatattat ggaaattcaa
    13501 cgtagaacca ctaatttttt acatttaggc tctttttttg caactttgac gatcttattt
    13561 tttctatgtt attcatacct taagacctca catgcgcctt ctagtgcatt aggctggttg
    13621 cttttggatc attctgatat cacagaagcc gaagaaaatc cgtttttttt gattttgtct
    13681 tctctttgcg gcttactgtt ttctgtttat ttcggtgcct atttttttca tcgacatcct
    13741 ggtacgttaa acgaagcttc aagcgtattg attgcattta aaacgttttc ttttttagca
    13801 attctttttt attcgtttaa tcacaatacg cttttcttct ttatcatgaa tggtttagtc
    13861 gtgattttat ccatttttac ttattttatt ttttcactca tttttagcca attgaaatgt
    13921 ccgctcttct ttcgattagt tcctgtcacc tgttttattt acagcttgtt ttcctttttt
    13981 gtccttgctt taatgccact gaccaaccct tcgacgatcc aagtcgcagg aaatctgttg
    14041 gatatgctct tcatcgtcag tctaggtgta tttatgtggc aaagaaaaaa caaacaaaat
    14101 aaaaagcatt ttgaagcctg actattacga cttcataaat gcttttttag ttttaaacac
    14161 ttcaatctaa aagaataacc caagattgga taaattatta atgactcgcc attcgtttct
    14221 tagtgattct ggattatcaa atggacttcc taatctaatc agctagttct tcccataaaa
    14281 tgccatactt gactgaatca taatattgat tatttaaaaa tctaactttt cttatcacta
    14341 cttcctttgt cattccacat ttctcaccat ttttttgcat tcctttgttt ccagaccatg
    14401 tagtgaatct aataggtggt agataggcaa aatactcaaa taattctttt aaccataaag
    14461 gaagagaaag gctcctcctg caagagtcag tataattttt gcttactgct ctcttaggtt
    14521 ttactcacta aaactgttcc atattctttg atataagaaa atgcatgcgg tataaatttc
    14581 ttgctcagct cagaaaagat ttgtcgttta agaaaggcca tttcctccat tgtcaatgaa
    14641 ggatccaatg ttggtaattc aatctcaaaa ttgttttttt cgacaatagg taattctaat
    14701 gtgaatgatt cttcttcctt tatagtattc gtcacaagta gagactgatg gaaaatacta
    14761 ggccggcgat ttttatattt attcttacgt atcctgtcaa cgataacttc tatttgatca
    14821 aaaaagtacg attcatttac gtctccaata agttcggcta attctttgaa tgccttcgtt
    14881 acaggaagct gattcttctg tacaaaaaag taattagcca aagtaagcgg gaagtgttct
    14941 atagaggaaa gtgtgataaa acggtacttc tcatttcctg cagttgtcct cagcaattct
    15001 gtctctcggc tgtttcttac tccataaaaa tacgcttctt tccgttcatc ttcgaaacaa
    15061 tacgcccaaa taacttctcc catcgctaat ttttgttcat caacagagag tctcttcaat
    15121 tgttcagcta tggtttcagc agccgaagtg gcttgttgca agtaatcttt aggatcaaat
    15181 attggaaagt tcaaatgata tcttcgttct tccctcttga ttaatcctgc atcgatcaat
    15241 aaatcaagaa aatgggaaaa tttattttgc gaaaattctt ttttcaattc tcttagaatc
    15301 gtttcttgtt ctcgatgttc atatagataa tcggtcaatg aagaaaaaag cggatcatcg
    15361 gtcagttttt gataaaagtt ttccttattt tttgaataat agttcatata tgttctcttt
    15421 tctatccgtt ttattttact taaaaggctt ttacgtaaaa aggaggaaga acaagagtca
    15481 taattgactg ttattctcct ccatttcttc ggcctttagt atgttctatg tttcttttta
    15541 tatcaatcgc ttatccattc attttgaatg cttcatacta ccatttgatt agctaaatac
    15601 agccgtcaat tgaggtacga cttgtttttt acgtgaaacg acacctttaa gcaaagcacg
    15661 gttgttggtc aaagttgttt ggaaagcttc ttctactttt tcttttcctt taccagcaac
    15721 aagtaattct gaatcactgt ctaagatgtt tgtgacaact aatacgaaca gatcgtagcc
    15781 atttgctttc atttcatctt ccattgctgc ttctagctct gcttgtcgat ccatcacttc
    15841 attaaggtcc actgtattga cttgagcgat acgaacgttg gaactgccca ttgggaaact
    15901 ttttgcatcc aaatcaagaa gaaccgcagc tgatttatca cttagatttg ttcctgcttt
    15961 caacatttca agtccataag tgtttagatc gacttcagcg attgctgcaa gttcttttgc
    16021 agctgcttca tcttcaggcg tacatgttgg tgatttgaac aacaatgtat ctgaaatgat
    16081 agctgagagc atgattcctg cgatttcttt aggaattgtt acttggtttt ctttatatag
    16141 ttttaaaata atcgtacttg tacatccaac tggttctgca cgatagtaca atggattagc
    16201 tgtttcaaag tttgcaatac gatggtggtc tactacagct aaaatattta cttcgctgat
    16261 atctgaaata ctttgttgga attcattatg atccacaagc atgacatctg cattttctgc
    16321 tttagctgac tctactactc gtggtgcaga tagctgaaag tggtctaatg cgtattgtgt
    16381 ttcttcatta ggtgtaccta gagcaactgc ttctgtttct ttacctaatt cattttgcaa
    16441 gtgtgaaaac gcaatggctg ccccgattgc atctgtatct ggattttggt gaccaaaaac
    16501 taaaattttt gacatgtcat tcgctccttt gtgatttctc ctatttaata atagcaaaaa
    16561 aacggaaaga agcaatactt atcttctttc cgatgcgacc tatcgcgtta aatattttgt
    16621 atactcttct gtatgaagca atcgtttagc attttcgaca cgttcttttg taggtggttc
    16681 gatcccttct aatggatatt tcaaaccaag tgtttcccac ttgtattttc ccatcgtatg
    16741 ataaggaaga atctctactc tgtctacatt tgacaaggtt tgaataaagt tgtctagtcg
    16801 gatcaaatat tcatcataat cacttcgctc aggaactagt acatggcgaa tccaaaccgg
    16861 tttgttgatt tttgacaaat attgagccat ttctaaaata ttttcattgt cccaatgcgt
    16921 tagtttttta tgctcttcat tatcgatgtg tttgatgtca aataacagta aatctgtata
    16981 cttcatcaat tcttgaaaac gtgaaaagaa aggttcttca tacgtaaaag gttttccgca
    17041 tgtatccaat gtagtatgca tcttccgctc ttttgctttt ttaaatagtt cgatcaaaaa
    17101 atcgatctgc aatagaggtt ctccaccact aacagtaata ccacctttat ctccccagta
    17161 aggtctgaag cgttctgctt tatctaaaag ttcatctgct gtgtattctt tccctccgcc
    17221 aatattccaa gtatctggat tgtgacaaaa ttggcaacgc atgcggcatc cttgcataaa
    17281 cacgacaaag cgcagtccag gtccgtctac tgaaccgaaa gtttcgatag aatgaacata
    17341 gccgattgtt ttttcttcca tttaagttca catcttttct ttgatttcat tttaagtaca
    17401 agttagctgt cgaagcgaag ctttctgaac aaaatttttc gcaattgccg cttcgttatg
    17461 tgtaaaattt acagggacgg aacatacaag tcctgcccct gtaaatcgtt tctttcaaat
    17521 aagcatactg attattcgat tttgatgcga tggctattca acgtcctttc gacgctaagt
    17581 cgaaaaactt ttttcacgaa ctttttacat tctgtcgtgt gaagttctca tcaagacatc
    17641 taattgttgt tctcttgtca agtcacggaa tttaactgca taaccagata cccggatcgt
    17701 caagttcgga tatttcattg gattttccat tgcatcacgc aataaatcat tactgaatac
    17761 attgacattc aaatgataag ctccttttga gaagtatcca tctaagacat tacgcaagtt
    17821 ttcgattctt gtatcttgtt cttttccaag acctgaagga ttgattgttt gggtatttga
    17881 aattccatcc aatgcacagc cgtaattcat tttagctgtt gagttcaggc tagctaataa
    17941 cccactttgt tccgcattgt aacttggatt tgctcctggc gcaagtggtt ttccagcttc
    18001 acggccatca ggagtatttc ctgtattttt accgtaaaca acatttgaag taatcgtcaa
    18061 taatgaagtt gttggttttg agttgcggta agttttatga cgtttgattt gtcccatgaa
    18121 gtattccaag atccatgaaa ctaattcatc tgcacggtca tcatcatttc cgtatttagg
    18181 gaagtcgcca tccacttcaa aatcaactgc tattcctttt tcattacgga ttgcttttac
    18241 ttttgcatat ttgatcgctg acaagctgtc tgccgcatga gagatcccag caatacctgt
    18301 agcaaatgtg cgttgcaagt cagaatccat caaagccagc tgagctgctt cataagaata
    18361 tttatcatgc atataatgaa tgatgttcaa cgtattgaca tatagttctg ctaaccaatc
    18421 catcatattc atgaagttat gtttcacttc ttcaaagtct agtatttctg atgtgattgg
    18481 acgatattct ggtccaactt gggcgccagt cacttcatcg actccgccat tgatggcata
    18541 taatagtgtt ttagccaagt tagcacgagc gccaaagaat tgcatgtctt ttccgacaac
    18601 tgttcctgat acacagcaag caatcgcaca atcatcagaa ccccattgtt cacgaagctg
    18661 attatcattt tcgaattgaa tcgaagaact ttcgatagcg attctgctag catatgttct
    18721 gaatccttct ggaaggtgtt cagaatacaa aacagtcaag tttggttctg gtgaaggtcc
    18781 catatttgtt aatgtatgaa gcagacggaa atcattcttt gtaactaatg aacgaccatc
    18841 taatcccata cctgcaatgg ataaagtagc ccagataggg aatcctgaga ataattggtt
    18901 atattcaggt gtacgcgcga atttgaccat acgtaatttc attactaagt ggtcgatcaa
    18961 ttcttgtgct tctttttctg tgattactcc attatccaaa tcacgttgga tatagatatc
    19021 aaggaatgct gagatacgtc cgattgacat cgcagcacca ttttgtgatt tgattgctgc
    19081 taaatatccg aagtatagcc attggacagc ttcttttgca tttgcagctg gtttagaaat
    19141 atcatagcca tatttcgcag ccatttcttt catttgcgct aatgcacgat attgttcagt
    19201 gatttcttca cgtaaacgaa tcacttcttc actcattgta tgataaccag tcatatcatg
    19261 atcttttttc ttttgttcca tcaaatagtc gattccatac aatgccacac gacgatagtc
    19321 accgatgata cgtccgcgac cgtaagcgtc tggaagccct gtaatgattt tgtttttacg
    19381 agcagcacgc atttcagcag tataagcgtc aaatacacct tgattatgtg ttttgcgcca
    19441 gtcagtgaaa atatgtgtca attcatcgtt tggtgtatag ccattgcttt ttagcgcatt
    19501 gttagccata ttgattccgc cgaacggcat gaatgcttgt ttcaaaggtt tgtctgtctg
    19561 tagaccgacg attttttcca aatctttatc caaatagcct gcatcgtgtg aagtaatagt
    19621 tgatacgatt tctgtgtcca tatcatagac accgttacgc tcgaattgga tatcatttaa
    19681 cttttgcaat tcatcccata atttttctgt tgcttctgtt gggccttcca aaaagctgtc
    19741 atcaccgcga tattcagtgt agttattttg aataaagtct ctagtgtcta cgccttcttt
    19801 ccatttggta cctttaaatc cattccattg ctccattgta tggacctcct aaatttctgt
    19861 tttatgtaac agtttttacg tgattagtat aacacagcac cctatctttg caagggtttt
    19921 cttgtttttt atttaacaat ttttatgttt tatttacata tatttaaatc aacgttgaca
    19981 taccaacatt taagcattgt gaacactttc atcttttttt gcaaacgtat aaggatttat
    20041 taaaaatgaa tgaaaaagag acgccacctg tattaataca gatggcgtct cttcattaaa
    20101 atactacaac agttacgact cgatgaaaat ctcaggagca tcgataactt cgatgacttc
    20161 tccacctttt ttctcatcca tcgcaaatga tccattcgat gttcgatcac ctatagggaa
    20221 atcagttggg tcaatcgtta actgctgccc tttttgattc atcaaggtta tttcttttga
    20281 tcttccttcc gacatataga taatacggtg cggatttttt ttcagctcac gcatgaccgt
    20341 cactccccgc ttcgcacgtg aagtttggct gatttcttga gcaagcatgc gtttaacagc
    20401 tcctcgctga gtaacgatta cgatcggcgt atcaccttct gctaacacaa gcagcccgtt
    20461 gataatccta tctccatctt tcaaattcat agacttcact ccagctgcct ttgctccaac
    20521 aacgggaaca tctgttaaag gatagcgcaa acccattcct tgatgcgtta ctaagaaaac
    20581 atctaagcct ggctgatctt ctttcagata cacagcaatc agttcatctt cttccgcctt
    20641 tagcttcata cagctgagcg gacggctctt ataggtgcgc catggttcga actctgtcat
    20701 tcgtgtttgc ttgatcaatc cattcttgct gatgaataca aatgttttct ctgcttgaat
    20761 tttttgatat gggaaaacag ctaaaatcga ttcgtctaca gacagattgg agattgtttg
    20821 agaaatgtgc tcaccagcat ctttccattt caaatcgggt agttcatgga cagggcggta
    20881 gatcacattt gctttatttg tgatcagaag aacatggtcc aatgtactca attcacctga
    20941 gtatagcaag tagtcgcctt ctcgcatccc gatttcttct ggtttggaag cactataaga
    21001 acgaaggctt gttcgcttca catagccttc tcgcgtcaca ctgacaatta cgtcttcttg
    21061 tgccactaag acttgcgtat caattttgat ttcttcgatt tcgtcttcga ttgtcgttag
    21121 acgagcggaa gaataatttt ttttcacttc tcgcaattct tttttcataa cagagaaaag
    21181 ctctttgtca tttgaaagga ttttattcaa ctctgtgatt tgcgcaatca agctttcgga
    21241 ttccttttga agctctgtga tatccgtgtt cgtcaaacgg tataattgca atgtgacaat
    21301 tgcttctgct tgttcttctg taaattgaaa gacgtcgact aaattctttt tggcgtcttt
    21361 tttgtcttta ctttcacgaa tcgttgcgat tacttcatcc agaatcgata aagctttcat
    21421 caatccttct acgatatgct gtcttttttg agctttggct aaatcgaatt gactacgttt
    21481 tgttatgact tgctttcgat gctcgatata acttcttaaa atgtctttca gtccaacttg
    21541 atgcggagtc atatggtcga tagcgaccat attgaaattg taattgatct gtagctcagt
    21601 gtttttgaac aaataattca aaattccttg agcattggcg tcttttttca attcgacgac
    21661 aatttgcaga cctgttctat cactttcatc tcgtacttca gctattccat cgattttctt
    21721 attcaaacgg atctcatcca tttttttcac caaggtcgct ttatttactt catatgggat
    21781 ttctgtgatc acgatttgct gtttattacc cttcattgcc tctatctttg ttttcgaacg
    21841 aagaataact tttcctcgtc ctgtttcata agcttttttg atttcatctt ttccttgcaa
    21901 gatccctcct gttggaaagt caggtccagg aatatattcc atcaattttt caaggctcgc
    21961 ttgtggatga tcgatcatat agattgtgcc atcgatcact tcagctaagt tatgagtcgg
    22021 gatttctgtt gcatatccag cagatatacc tgtcgatcca ttgacgagaa ggtttgggta
    22081 tcgagctgga aggactgttg gttctttttc tgtatcatca aaattccaca cgagatcgac
    22141 tgtttctttc tcgatatctg ctagcatctc tccacttaac ttggataatc tggcttcagt
    22201 ataacgcatc gcagcaggtg gatcaccgtc catactcccg ttattcccgt gcatttcgat
    22261 cagtacttcc cgcaacttcc agtcttggct catgcggacc atcgcttcat aaatactgat
    22321 gtcaccatga ggatgataat tccccatgat atttccgaca gattttgctg atttacggaa
    22381 tcctttgtca tacgtattgc catctttgtt catggcaaat aatatccggc gttgcactgg
    22441 cttcaatcca tcacggatat caggcagtgc acgttcttgg ataatatatt tggaataacg
    22501 tccgaagcgg tcacccatca cttcttctaa agttaattct tgtacttctt gtcgattttc
    22561 catcaggtga cctcctattc tacttcaaat aactgattgt tttcattttt atctgctcgt
    22621 tcttcatcta ataaatcatt agaaactgaa ggagagattt cagtatcctc ttttttatct
    22681 aagatactgc catcttcttc gagcgtaaat tgcacgtgat tttcgatcca ttttcttcga
    22741 ggttctactt tgtcacccat cagtgtggtt actcgacgtt cagcttgcgc agcatcatcg
    22801 atacggacgc ggatcaacgt acgggaagtc ggatccatcg ttgtttccca caattgttcc
    22861 gcattcatct ctccaagtcc tttatatcgc tgcagcatat atcctttgcc gactttttta
    22921 atcattgctg ccaattcgtc atctgtccac gcatattcaa tgacttgctt ctttccttgt
    22981 cctttggata ctttatataa aggcggtaac gcgatatata ctttcccagc ttcaatcagc
    23041 ggtttcatat aacgataaaa gaaagtaagc agtaatactt gaatatgggc gccgtctgta
    23101 tccgcatcgg tcatgatgat tactttgtcg taattacagt cttcgataga aaactcagga
    23161 ccgactcctg caccaatcgt atagatcatc gtattgattt cttcattttt caagatatct
    23221 tgcattttag ctttttcggt attgatgact tttcctcgta aaggtagaat tgcttggaac
    23281 tttctgtctc ttccttgttt agcagatccg ccagcagaat ccccttcgac taaatacaat
    23341 tcatttttct tagggtttcg ggattgtgcg ggtgtcaatt ttcctgaaag aagagattcg
    23401 ccttttttac gcttcttccc atttcggctt tcttctctgg ctttacgtgc tgcttctctc
    23461 gcttctctgg ctttgattgc tttacggacc aacatctggc tcatttcgct attttcctgc
    23521 aaataaaagc ccatttgttc actgatgacg ttatctacta cggtacgagc aactggcgta
    23581 ccaagttttt cttttgtttg cccttcaaat tgcagaagat tttcaggtac acggatagaa
    23641 agtacagcag ctaacccttc tctgaaatca ctaccttcca gattcttgtc ccgttctttc
    23701 agcaaaccaa cttttctcgc atattcatta taagatttcg tcatcgccgc tttcatacca
    23761 gcttcatggg ttcccccatc ttttgtccga acgttattga caaaagataa aacattttct
    23821 gaataaccgt cattgtattg ataagcgacc tctacttcga taccttcttt ttctcctgaa
    23881 aaataaacaa ctggtgtcaa tgtatctttt tcttcattca gataatcaac aaattctttg
    23941 attccttctt cgtaatgaaa aatttccttg actggttctt ctccacgaag atcagaaaga
    24001 gagattttaa cgccttttag aagaaaggca gattctctta accgttcggc taaaatttca
    24061 tatgaaaatt tcgttgtact gaatattgta tcatctggta aaaaatggac agtcgtcccg
    24121 tttgcttttt ttgtttttcc tatctttttc aaagtaccgt caggtttacc gccgttttta
    24181 aatttctgct gatactctac gccatctcta acgatcgtta caattagcca tttcgataag
    24241 gcatttacca cactggctcc tacaccgtgc agtccaccag aagttttgta ccctccttga
    24301 ccaaactttc cgccagcatg cagcacagta aaaatcactt caactgttgg tattccggaa
    24361 gcatgcattc ctacaggcat cccacgtccg ctatctgcaa cagttatact attgtcttca
    24421 tggatggtca catcaatctc actgccataa cctgataatg cttcgtcaac tgcattatcg
    24481 acgatttcat agactaaatg atgcaagcct cggctgtcag tggatccaat gtacatccct
    24541 ggtctttttc taactgcctc taatccttcc aatacttgga tggacgagtc attgtattcg
    24601 ttgtttactt tttttgccaa ggcaaacgct ccttcaataa tactttgcgg caaaaccgca
    24661 ccacgattat catactagaa aaggtcgtga aaaaaaagag ggtagacgag aaatcaattt
    24721 taattatctc ctaaccgctt tttcgacatt cccctctatc gatcatctct tctttgtggt
    24781 catttttatt tttggttttc tttcaactta ccaagttcaa tcttaataca acgatccatt
    24841 acgatatctg tacgtcctgc ttttcttagc atctcagctg cttctttgtt ttcaatccct
    24901 aattgtgccc agaacacttt agcatcagtt ttcaaaaaat cacctgctat ttcaggtaaa
    24961 aattcactcc gtctaaatac atctacgata tcgattggat catcgatttc tgtcaaattc
    25021 gcatagactt tctcgcctag aatttcttca ccagccaata atggatttac tggtatgatt
    25081 ttatatccat tgtcttgcaa tacctgtgca accatgtaac ttgttcgttc tggtttattg
    25141 ctcaagccta cgacggcaat attttttgct tcttccaaat agttgaaaat cgtttcttgt
    25201 gttggatttt ttacagacat ttctgccacc ccttgctttt ctttttattc catctattat
    25261 acttgtatct ttcatttttt caattgttcc tgttacctat tcatgctaaa ataaaggata
    25321 gttttcaact tgaaagaggg taaaaaatga aattgatctt attacttatt ttagcatatc
    25381 ttttaggttc tattccttcc ggtgtctgga ttggcaaatt gtttttcaaa aaagatatcc
    25441 gacaacacgg gagcggtaat actggaacga ccaatacatt tcgtgtatta ggcaaaacag
    25501 ccgggattgt tgtcctgctt atggatattt taaaaggtac attggctact tgtttgccga
    25561 tgatcttcca cctttctggg attaaccctc tttggtttgg ggtatgcgcc attcttggcc
    25621 atacatttcc gatttttgct gggttcaaag gaggaaaagc tgttgcgaca agtgcaggaa
    25681 tgcttttagg atttaatcct gtattttttg tttattcttg tatcatcttt atcgttagtt
    25741 tattttgtac aagtatggtg agtttgagca gtatgatcag tgcagtattg atcactttat
    25801 ctacgatcgt ccttccttat gtagctcctg tgattttggc taagcccaat tggttactga
    25861 cgatcattgc ctttttagtt tcttccttta tcttttatcg gcataaagac aatatcaagc
    25921 gtatcagaaa ccatactgaa agtcgaatcc cgtttggttt gaatagcagc aagaaaaaat
    25981 cctgatactt tttcattcca aagagataaa acgggagtgt gacaaatcga tgtcacactc
    26041 ccttattact tacaggatag cttttttaca caccttggta aacggtgttc cctgctaact
    26101 tctcggtcac aacctcttac ttcactgtga tggaatattt tgtcttgaag atttcatggg
    26161 cacctagttg attgatccct actttttcca tcaagtttcc actactgttc accgtgtcag
    26221 cgattccgca ccacggttcg atacaaacga aaggcgcttc ttttggataa ggagaccaga
    26281 tccctacata aggcatatct ttatagctta aagttacgct atgggaagat ttttcacttc
    26341 gaatggcgta cgcatttaga ccccttgttt caaaaaccaa ggcatcttgc tcaaaaagtt
    26401 cacgattcaa agccagattc gtatttgtct gacctaacgt cttttgatcc atatcgatga
    26461 atgggccttt caatggtagg cgtaatcttg atttcaatgg agaaaatgcc agatagaaat
    26521 cttcaaatga caatccttct tcaagaggta cattgaaagc aggatgtcca ccgatagaaa
    26581 agaacatttc tttttcaccg gtatttgcca cttgataatg aaccgtgatg ccgtctcctc
    26641 ctaattcata gctgatcact aattcaaaat caaatggata cttttctaat gtctccggcg
    26701 tactccttaa gatgaaacta gccatttctt gtccatgttc aatgacttca aaatccatat
    26761 cccgagcaaa tccgtgttgc cccatttgat atgttttccc ttgataaaca tactgatcat
    26821 cttttaaacg tccaacaaaa gggaataaaa ccggtgcatg tctgccccaa tacgctggat
    26881 caccttgcca gatatactct aaaccatgtt cttttgattt cagactgatc aattccgcac
    26941 cgtgttcagc gatttcggcg atcagctggt cattttgaat aataacagtc attgccattc
    27001 ctccaacttc gacttacttt ttaaaatggg aaggctggaa caaacatttc tatctgcccc
    27061 agtcccctta cttctaataa ctgtgttttg ctaactcgtc tttaaaacgg gaattcaata
    27121 cttttaaata agttcccttc atgcctaacg aacgagattc aatgattcca gctgattcca
    27181 attttcgtaa agcattgacg atcacagaac gagtgatgcc gatactatcg gcaatattag
    27241 aagcagtcag acgaccttca tctccatcca atgcttcaaa gatagcttgt acagccttca
    27301 attcgctata agataatgtg ttgattgcca tttggacagc cgttgcactc cgtacatctg
    27361 cttcgatgct tcgagacttc tgataaagga tctgcatacc gacaaccgta gctccatatt
    27421 ctgctaagac tagatcgtca tctgcaaacg attgttccat acgagataag ataatcgtac
    27481 ccaaacgttc gccagctcca aagatcggaa cgacagtcgt cagaccaaat ggatatttct
    27541 ctcttgactc taccggaaat gcagtaatat cactagtaat tgggatatta gcttcagttt
    27601 tcatcaactg tgccactgta tcagtataag attcaggaaa ttgtttctca acaaacattg
    27661 ttttgattcg ttcattgttc acatcgtgac gttcattata acctagtaat actccgtcac
    27721 ttcctatgat ataggtgttg ctgtcaagaa taccacctag tgtgacagcc attttatcgt
    27781 aaggcaaatc tgcttgcatg tcaaaagtat tcttttgctg caaaagtgtg tttatcttgc
    27841 gggttttcgt tagcaagtct gtcattgtcg tcctccgatt ttttataaaa tatagcgact
    27901 taaatcttca tttgccgcaa ttgagccaag tttgtcatcc acatatgctt ctgtgatcgt
    27961 tatttctccc atttgcatat ctggtgcttc aaataataga tcttctagta gtttttccaa
    28021 aatggtatgc agtctgcgtg cgccgatatt atctgtgtca cggttgacat cgaaagcgat
    28081 ttgagcgatc cgttcaattg cttcttttgt aaacgtaact gacacatttt ctgtaccgat
    28141 caacgcgacg tattgtttta ctaaagcatt atttggttcg gtcagaatct tcacaaaatc
    28201 ttcagctgtc aaatcatcta attctacccg tatcgggaag cgtccttgaa gttctggaat
    28261 tagatcactt ggtttagaca aatggaaagc tcctgaagca atgaatagga cgtgatctgt
    28321 ttggatgatc ccgtattttg tgtttacttg tgaaccttcg acaattggca atatgtctct
    28381 ttggacgcct tctctggata cttctccaga ttgctgtgat ttagaagtga tcttatcgat
    28441 ttcatcgata aaaataattc cactttcttc cgctaatttg attgcctcac tatggatatc
    28501 agcatccttg actaattttg ctgattcttc cttgatcaat aactctaaag cttctttgac
    28561 tgttaccgtc cgttccactt ttttcttcgg tgtcaaagca cctagagttt catttaggtc
    28621 gatccccatt tgctccaatc cattgttcat cattggtgca ggtttctttt ggtcttcaac
    28681 ttcaatggtt acttcacgac tatccagtaa acccttttgt agttgttcca agactgtacg
    28741 gcgattgatt cgaatatctt ctgtcacttc ttcttgcggt tcagcggtat tttgctgact
    28801 agcattaaaa agattcatca tttgttcaaa ttgattagtg gattgtttct gttctttttt
    28861 gataccaggt accaagattt ttaccaaacg tttttctgca ttttttttag cacttgtgta
    28921 tacacggctg tactgctctt tttctacgat ttggatcgca ttttctacta aatcccgaac
    28981 cattgattct acatctcttc cgacataacc gacttcagta aattttgttg cttcgacttt
    29041 gacaaatggt gcattgacga tttttgccaa acgtcgtgcg atttctgttt taccgacccc
    29101 tgtaggtccg atcatcagca tattttttgg tgtaatatct tgttgcattt tttcatctaa
    29161 ctgcaaacgg cgatagcggt tacgcaaagc aacggcaaca gatttttttg ctgcgtgctg
    29221 tcctacgata tattcatcta attcacttac gatttgtctt ggtgtttgtt ttaattcata
    29281 catatctact cacctcttac agttcttcta cgataatatt atgattagta aagatacaga
    29341 tatctgcggc aatatttaac gcattttctg caatttcttt cgcactcatg tcgttttgag
    29401 catagttttt cattgctcgg gctgcagcca acgcaaaatt ccctcctgat ccgatagcta
    29461 agataccatc atctggtgtg ataacttctc ctgtacctga aacaagaagc atttctttat
    29521 cattcattac gatcagcatc gcttcaagtt tttgcataga ttgctgtgtc cgccattctt
    29581 gagctaattc gacagctgcg cgttgtagat tcccgttata ttcgtttagt ttgccttcaa
    29641 atttttcttc taaagtaaac gcatctgcaa cacttccggc gaaacctaca acaacttctc
    29701 cattgtagat acgtcgtact ttctttgcag tgcctttcat gacaacagat tcacccattg
    29761 ttacttggcc atctccagcc atagcaaatt tcccgtcttt ttcgacggca cagatagtgg
    29821 ttgaatgaaa tggtgattcg accatgtttg tttcctccta aatttgttct tttccttatt
    29881 tttacgctct tggatggaaa gaacgatagt ttttttgtaa actttctttt gttacatggg
    29941 catagatctg ggtagtcgat aaattggcat gtcctagcaa ttcttggact gtccgcaaat
    30001 ctgccccatt atttaataaa tgagtagcaa atgtatggcg cagcatgtga ggatggatat
    30061 cactatccaa actgcttttt ttgatcattt gattcaagac atattcaatt ccagtaggcg
    30121 tgattggttt tccatgatga ttcacaaaaa cgatatcatg ctcttcgtga tattttgtca
    30181 tcaatacctg gcggccttcc ctgaaatatt cttgcagagc atcttgagca aaagaaccta
    30241 gaggagcata tctctctttg ttccctttac catggatcaa catgacctct gaatcaaaat
    30301 caatgtctga taccgacaaa ctgctacact cacttaaacg gatgcctgac ccgtaaagga
    30361 cttccagtaa agcgcggttc ctcaaatcca aaggactatc tcctgctacg ctgtcaaaaa
    30421 gtgcttgcat ttcattttca taaaaaaaac gtggcagtct caaatttttc tttttgagat
    30481 gaacgtaaga aaatggattt tcttttatca cttcttcttt gagaagatac tgataaaacg
    30541 aacgtaggct ggctatcttg cgactgatag aatttctgct atagctagga cgatgatcag
    30601 ctaatgcact caaatagaca cgaaccgtaa aatattccgc cttcagcaga tcagcgtctc
    30661 cagattcctc caaaaaatgt ttgaaatgga gaatgtcttc ttcatatgct tctttcgttt
    30721 tttctgaata tcctctttcg acaatcaaat aacgcaaaaa tttttgttcc cacgtggctt
    30781 ctgtcatttt ctcaccttcc ttttgtccca gagaataatt tagcacagcg tttataaaaa
    30841 gacaaataaa ttgtcagaat ttaaccaata tttctaagtt tgttcacaat tggcgcaatt
    30901 cctcacattt tgtttgagaa attcttaaga aaaacgcaag aaaaagagcg agactatccg
    30961 tctcaccctc ttcatggagt ttccttactc atttgggatt gcagtttttt ctaattctgt
    31021 ttttattgcc tcattagctt ttaaagctcg ttgtgcaatt gcttcatatc ttgctttttt
    31081 gtctcgaatg cgctctggca gttcaggaaa cagaccatag ttggcattca tcggttggaa
    31141 atgttttcct tccgcatgag taatgtagta agccatactt ccaatagctg tttcttgtgg
    31201 aaactcgact ggttccattt cttttgctaa gcgtgcggcg ttgattccag caagtagtcc
    31261 gctcgctgca ctttcaacat agccttctac accagtcatc tgacctgcaa agaacagatc
    31321 ttcgcgtttc gttgattggt aagtcggttt cagcaattct ggcgaattca taaagctgtt
    31381 tcggtgcatc acaccatagc gaacgaattc agcattttct aacccaggaa tcatccggaa
    31441 aacacgtttt tgctcgcccc atttcaagtg agtctgaaag cccacgatgt tgtataaaga
    31501 agctgcagca ttgtcttgac gcagctggat aacagcataa ggacgtttgc cagttttagg
    31561 atcttccaat ccaactggtt tcataggtcc gaaaagcatc gttttgaatc ctcgctgtgc
    31621 cattacttca attggcatac atccttcaaa atatttttct ttctcaaaag atttaagttc
    31681 tgccacttcg gcattgatta gtgcctcatg gaaagctttg aattcctctt ctgtcatcgg
    31741 acagttcaag taagctgctt ctcctttgtc atagcgggac ttcaaatata ctttatccat
    31801 atcgatcgta gctttgtcta cgattggtgc agctgcatca tagaaataaa aaccatctga
    31861 accattgaat gctttgatgc tttctgctaa tggatgagaa gtcaaaggtc ctgttgctac
    31921 tacggtgatt ccttccggta tttcagtaat ttcttcgttt atcactgtta ctaatggatg
    31981 ctctttgact tttcgggtaa ttgtttcaga aaaagaatcg cggtcaacag ctaaggcacc
    32041 accagctggc actgctgttt catctgccga agtgattact accgaattca atcggcgcat
    32101 ttcttctttc aataacccta ctgcattagc caaactgttt cctcttaatg aattggaaca
    32161 tactagttca gcaaaattac ttgtgtgatg cgcctcagtc gatttgactg gacgcatttc
    32221 atataaacgg acagggactc ctgcttgtgc gatctgccaa gcagcttcac ttccggcaag
    32281 ccctgctcca acaacattta ccattttcaa tgaaagaacc tcttttctat tatttttgga
    32341 tgtcttcttc gtaatctcca tttacacaga ctacttgttt accgcctttg actttcttct
    32401 cgaccagata tccgtcacat tttggacaat ttctgcccac tggtttatcc caagaagtga
    32461 attcacattc tgggaaacgg gaacaaccat agaatagtct gtttttctta gattttcgtt
    32521 caatgacttg tccttcatga catactgggc aagtcacacc gatttctttt acgattggtt
    32581 tcgtattccg acaatcagga aaattactgc aagcataaaa cttcccatat ttccctaatt
    32641 ttatcaccat cggatgtcca cagacatcac aatcgaatcc tgctggttca tctttgattt
    32701 gaattttttc gattttttct tccgcattcg tcagttcttt ttcaaacggt ttatagaaac
    32761 gatcaaccac tttgacccac gcttccgtgc cttcttcaat tttatccaaa tctccttcca
    32821 tttctgctgt gaaatggata tcgacgattt gagggaagaa ttcacagatt aatgaattga
    32881 caatttctcc tagttcagtc ggctcaaatc ttttttgtgt caattttaca tagtagcgtc
    32941 tttggatcgt atcaagtgtt ggtgcataag tggaaggtcg ccctaccccg ttttcttcta
    33001 gtgcacgaat caacgtagcc tcactaaaac gtgctggtgg ttgagtaaaa tgttgttttg
    33061 gttcaatatc aacagattgg actacatcgc cttcttcaag ttctggaaga atattttctt
    33121 tctcttcttt gccgtcatct ctaccttcca catacacttg catgaatcct ttgaatttga
    33181 tttttgaacc gttcgcaatg aagatgacac cattttgttc taatgtcact ttcattgtat
    33241 ctaaaatagc tggtgtcatc tgactagcca caaaacgtga ccagatcaat gtataaagtt
    33301 tcaattgatc tttatctaaa tattgtttga gttcatctgg tgtacgaagc acactcgttg
    33361 gacgcacagc ttcatgggca tcttgtgcgc cttgagcatt tttgatcttt cggtgatcat
    33421 gtctagaaaa ttcttttcca tacgtatctt caataaatgc tgcggcctct gcttttgctg
    33481 tatcggcaat ccgggtagaa tcagtacgca tgtatgtaat caagccgact gttccttgtt
    33541 tacccaaagt gattccttca tataattgct gtgctaccat catggttttt cttgttcgaa
    33601 agtttaactt acgggcagct tcttgttgca ggctacttgt agtgaaagga ttcgcagggt
    33661 ttcttttgcg ctctttcttt tctacttttt taacttcgaa gtctgttcca tcaattctag
    33721 cagtgacttc ttttacactt tgtgcatctg gtaatttctt tttcttaccg tcgattcccc
    33781 agaaatttgc tttgaatttc ttgcgagctt ttttaaaatt accgtcgatg ctccaatatt
    33841 cttctggaac aaattctcgg atctcttttt cacggtcaat aataattttt aaagcgacag
    33901 attggacacg tcctgcactt aaccctttct tgaccttacg ccagagaata ggactgatcg
    33961 aataaccaac gattctgtct aaggtacgac gagcttgctg tgcatctact aaatctacat
    34021 cgatcgttct tggttcctta aaagctgctt tgactgcgtc ttttgtgatt tcattgaaga
    34081 ccacccgatt tttttctttc agatccaacc caagtaggta cgctaaatgc caagcaatcg
    34141 cttctccttc tctatccggg tcacttgcca agtaaacttt ttgagctttt tttgctgcgg
    34201 ctttcaggct tttgatgaca tcgccttttc cgcgtataga aatataatgg ggttcataat
    34261 tgttttcaaa atcgataccc attttacttt tcggtaaatc tcttatatgg ccaacactgg
    34321 ccattacttt atagtttcgt ccaagatatt tctcaattgt cttggctttt gcaggtgatt
    34381 ctacaatcac taaatattta tacgccatta ctgaatggac tcctttccat tgtcgtgttc
    34441 ctactattaa aagaggattc atacaaatcg tagctaatca tatccattca gaaaacgttt
    34501 gtcaagaaaa gcaaatgaaa agtatggtgt tattctttaa attctgccaa gatatcttca
    34561 cccgaaaccg tgcaaactgc accgtcttgg atcaaatgat gacatccggt agaatgttct
    34621 gttaaaatat ttcctggaac agaaaaaact gttcttccaa gatccaatgc ttgctgtgct
    34681 gttatcagag agccgctttt tttcttggct tcaaagacac atgttccttt agacaaagct
    34741 gcgataatcc gatttctcat tggaaaacaa tgctttttcg ggccggattg aggaggatat
    34801 tcactcaaaa gaagatgatc atttgcaatc acctcttgca agtcacgatt ttcagcagga
    34861 tagacttgct ctatccctgt tccaatgact gcgattgtcc gtccaccatg agagattgct
    34921 gcttggtgac cgtatgtatc tatccctttc gcgcagccac tgacgatcac atatccagct
    34981 tctatcactg gttttagtaa ataataaact gtttttttgg ctaaagcaga agtgtgtctt
    35041 ccaccaacaa cgcttaacat gttacaagaa agtaaagata gatcaccatt ataaaacagt
    35101 acaattggcg gataggtcaa gtgaagcagc tgagggggat atttgggatc aaagcaagtg
    35161 ataaacgact gtttcgattg gattttgccc cagttagcgt gaatttcctg ccaacttttg
    35221 cgaaacagct cccggtgttt ggttatttta cctatcttaa tgatgtcttc aaatccgatt
    35281 tctttataag gatactgcat catccagtta gcaagtgccc attttccttg actactgatt
    35341 ccttttgtat aagcaagttt caataaattt tcttctattt gatacatcat aaaaccgcct
    35401 ttcgtctctc tttctaataa gatacgtaaa agcggctgtt ttttattgta aatatttttt
    35461 tacaggtgca aaacttttac gatggattgg cgtaattcct tgtcgttcaa gtccttctaa
    35521 gtgttccttt gttccataac ctgcattatg cgagaaacca tatccaggat aaagcacgtc
    35581 atattctttc atcaattggt ctcgatatac tttagcaatg atacttgcag cagcaatcga
    35641 cacagatcgt gcatcccctt tgattatttt ttcctgctga ataggcaaat ccaaggtcat
    35701 cgcatcgatc aacaaatagc ttggtacaat ggacaatttt tctactgctt ggatcatcgc
    35761 taatttactt gcttcataaa tattcacatc atcgattgtc tgctgatcaa cgatcccgat
    35821 cccgattgcc agggcttttt cttgaacttg ttgataaaga agttctcgct ttttctctga
    35881 taattgtttg gagtcattca gccctaatat gatctcattt ttcggcaaga taactgcagc
    35941 tgccacgaca ggtccagcta atggtcctct tcctacttca tcaatgccgg caatccattg
    36001 gtgaccttgt gcgtaccctt gcttttcaaa gcaaaacatt tcttcatatt tttccttaat
    36061 taatgcttcc tttttcaatc gtcgttcaaa agaagccagt gcttgctgca cgcctttgcg
    36121 tggatcattt cttaatgatt ctagtgtagg atcatctatt ctctgtatgc ttttcaatcg
    36181 ttctttgata ctttggatgg attcagtcat cacttttttg ctccatttct tcgcaacgat
    36241 ccagtgtgta tcgtccaagt tttccttgac gaatatcatg cacgactaat tcgctgccac
    36301 gatcatagtc ttctttatac ccacgttttg ctgtaatatc catcagtaat tccggtgcca
    36361 atttttcttc ttgctcgatt gataaaccat aacgatcgct gattcttcct gaataatatc
    36421 gggcaaaaaa gtctaatccg taaatcgcta aatcatctaa atggacaagc tggtctttga
    36481 tcgcgcctgt cagcgctagt tttttgccga tttcttcatc ttcaaatttg ggccataaaa
    36541 tccctggtgt gtctaacaat tccaactcat tacctaaacg aagccactgc tgaccttttg
    36601 ttacgccagg cttatttcct gtctgtgcaa ttttcttgcc tactagtcga ttcatcaacg
    36661 tagatttccc aacatttgga atacctaaga ccattgcccg aatagcgcga ggcttgatcc
    36721 cccgagcagc atctcttgcc cgtttttctt tcaatgcttc tttagccgca ggtactagac
    36781 ctttaattcc tttactttct tgtgccgtga tagctaatgc aagatggcct tgtttacgaa
    36841 aatattcttg ccacagcttt gtctgttgtg gatctgccag atccgcttta ttcaataaaa
    36901 caaggcgagg tttttgctga atgatctgat ctagcattgg attacgagaa gataaaggta
    36961 atcgtgcgtc taccaattca aatacgatgt ccacatattt cattttttca gaaacttctc
    37021 gtcgggcttt tgccatatgt cccggaaacc attggatggt cattgttctc tccattcctt
    37081 tcataccgga atattccccg gctttacttg tttttttctt tttcaatata aattcacttt
    37141 tttattataa agaaattcca tctattagtt aagtgaaagt gaaccagtcc tcattctatc
    37201 acatcttcac ttttttgatg atgcaaattt ttattttggt ttctatatat gaatctaaat
    37261 ttttgacagc gtttcctaaa taagagatga tagacgaaca aaacagaaag gagacgaaac
    37321 aaatgaatag tatggttttt gttaattttc ctgttgctga tgtcaatcgt tccgttgctt
    37381 tttatgaaaa gctgggtttt aaaaaaaatg aagaattttc tactgaagaa gctggttcaa
    37441 tggtatggga tgacactttt tggataatgc ttctctctca tgatttttat aaaaaattta
    37501 taaaagataa agaaatagct gataataaaa aaacaagtgg tgctttgatt tcgtttagtg
    37561 ttgaaaatgc ggatgaagta aaaaaatttg ctcaaattgc aaaagaaaat ggtggtactt
    37621 tccacgaagt agatatggga atgcctgaag aagaaatgtt ttcattagaa gtccaagatc
    37681 tagacggaaa tacattagaa cccgtatgga tgaagatgta agcagataac taatctgacg
    37741 ttttttataa caaaaaaaca aaggcggatg atacgataag tattctccgc ctctattttt
    37801 tttattcgta caatctcttt tttacagttt ataaaagcag tcttctcacc ctttttttaa
    37861 ttgttagatg ccagtgtatg taaatcacca atgtgtcatg acacattggt gattttatgg
    37921 tatcctttta ttattaactg acaaaggaga gaatattttg aacactttga ttgcaaaaga
    37981 cgtttttaga ttgcccgaaa tgaatgcaag attgttgtcg acctctgctc ttttattagc
    38041 ccttgatgtc atcttataca agatagcgat tggtcctgct tattttcaaa tcacattcgg
    38101 atttttaagt atggcgctta tgggttatct atatggaccg atctgggctg gtttgcttga
    38161 aatgttgtcg aacactttaa atttcacgat atttggttca ggaacgtttc aagctgcttt
    38221 tcttatcacg gctttccttg gtggatttat taatggctta tttttatatc ataaaaagat
    38281 aaacctgcct tccgtcatcg ctgcccaatt attgattatg atcccagtca gcctttttat
    38341 caattcttgg ctgatgtctg ttttgtttgg tgcagatttc aaagtaattt ttctaggtag
    38401 attcatcagg aatatgatcc aaatccctat tcaaataatg gttgtttatt catttatcaa
    38461 aactttagag gctagaaaag tgtttaaacg agctgtttga ttttacgtac taaggtagta
    38521 aactgatttt ggattaaaca ataaagcgtg cagtctcaac agactgcacg ctttattgtt
    38581 tctcactgga tccattttat ttcatcaagt ggataataga caaatcttgc tttacctaga
    38641 atatcagttt tattgatcgt gccaaacgaa cgactatctt ttgaaactct tcgattatct
    38701 ccaagtacaa aataattatc ttccggaagc ttggattgtc ccgttagctc ttgtagtgta
    38761 aagtccgtcg tataggatgc atttgcatga tctgatttca ggtttttagt tagataaggt
    38821 tccttaacta ctttcccatt gatcttcaat tgatcatttt ggtagctgac attttctcct
    38881 ggaagaccga ttactcgttt gatataaatc gtgccatctg ctaattgaaa aacaacaata
    38941 tcaaatcgtc tgatctccga aaatttttcc atcacaacca tatcaccttg cttcaacacg
    39001 ttttccattg aattgccttc cactggtacc gggatgaata aaaatccccg caacatgaac
    39061 gcaaggaata cagaaacaag taagtatttg aatacaagcc agaagcgatt aatatagcgt
    39121 tgtttttttg tcaatctcta tcaatccatc cctctttttt tcattctttc tttattataa
    39181 gaaaaatatc aaaaaaatgc gactagatag ctgaaataaa aataattctt tcaattaggc
    39241 tattggacaa aaaacttttt tgatcataaa gtacaaaact atctcttata tgtcatgatt
    39301 attttctaaa tatttttccc atgcttcgtc aaagatatcc atggacggca aatagtcgac
    39361 attcagttcc agataattag aaatttcttc gtagctagag ctgtgcttag gaaattggat
    39421 gtctttaccg gcttctgtag cgaaaacaga taaagcatca tgtgtgccac cgcctcgcag
    39481 tgtcattaaa taatgaaaaa agcttcgatt cacccttcgt tcctccaatt ttcttcgata
    39541 aaggcagccc ggcgtgcatg gtttctttta aaattttcag gatgcttttt ataatactct
    39601 tgatggtctt cttctgctag ataaaatggt tgggctggtt cgatttttgt aacgattggc
    39661 tgttcgaaac gtccactttc agctaactgt ttcttacttt tttcagcaat gatccgctgt
    39721 tcttctgtca aataaaagat caccgggcga taattgtcac cgcgatcctc gaattgtccg
    39781 aaagcgtcag ttggatcagt ttgctgccag taaagttcta ctaattgttc atatgaaatc
    39841 aatgttggat catagataat ctccactgct tctgtatgtc cagtcgtttg gctttttact
    39901 tgttcataag tcggatctgg tacatgccct ccagtatatc ctgacatcac tgtatggata
    39961 ccaggaagcg tgtcgaaagg ctggatcata caccagaagc agcctcctgc aaatattgct
    40021 cgttccatta tgattccccc tctaatacta ctcatccgat gattttttat tttcttttgt
    40081 cttgctttca gtactgctgg tgctagtttt gttggtattt gagttgtttg aagcatcaga
    40141 ggtatctttt ggcaaatata gactaaaccg aatgtcatca tttactaagt cgattttatc
    40201 tgctttaata tacatcccgt tttgcattcg gaattgatcc aacctaagca tgatagtcag
    40261 atcatctgta ttgacttcga tccaatctgg taatttatag tttctcttga tcatattcat
    40321 cacatctttg attggcaaac tcaatgttcc gatagaaaga cttctagctt ttagttggac
    40381 atttccgttt tccatcacat acggatcaaa atataaatag aaatcgatag gaaaacctag
    40441 tacttcgaaa gtaccattga gtagtgcttc attttccaaa taaaatttat attcaatatc
    40501 actatctttt tgatactcac taaggaaaaa gctgatgatt tgattgactt tttctttatt
    40561 tgaattgatc gttaagacag gatctccttg tctttccgta agagctggta tttctgggag
    40621 ttctggttcc cgattagcaa aaatacggct gcctaaaaat acggtcgaac caagtactac
    40681 cccaagaagg ataaggaagg cgaatttcca gtaatttgtt ttctttgttt tgtttgaaga
    40741 tacgtcagat cttgttttca tgtttattga tcatcctcct tctctaacca ttggttttgt
    40801 gtctcgatca gctgatctct cactgcattt gccatcaatt gataacctaa attatttgga
    40861 tggaaatgat cttcttcata gagcacatta tttttgatgc catttagatt ttctgtcgtg
    40921 ctagttgttt gatctgttcc ttcttctgtg acacctactt cctgattcaa tccttgataa
    40981 agcaaatcat tgattgggat aaagtagcag ttcggcattt tttttgtcac cgtttctgtt
    41041 cctttgttcc aattgttaac aattgtctgc atgtcagtga tctcaggaaa gttcaaataa
    41101 aatggattgt agatgcctaa aatgtaaata ggtgcggttt tattgaggga tcgaaattct
    41161 tccaatagtt ctgtgacatt ttcctgatag tttttcagtg gctttttaaa ggaattgacc
    41221 gttaacccga ataaattatt ttggataact ttcatcaaat cattaccgcc aacagtcagt
    41281 gtgataaaat cagctgtttt gatattgttt cgaatttctt cttttgtttt tactcgcttt
    41341 aagatctggt cacttcgttc accatttaca ccatagtttt ctgtttcaac cgcggtcaaa
    41401 ttataacggt cttttagatc atttgcgaca aggggaacga atcctccttg cttggtttga
    41461 tctcctactc cttcagtcag cgaatctccg atagctatgt agtgaagttt ttctttttta
    41521 tttggatctt ctctcacagt agttactggt ttcattagtg ggccagcttt cggtatagaa
    41581 gcagctaaac ctgcatagat gatgatcgca attaataatg ggaacaaaac gaggatcaaa
    41641 tgtcgtttcg ttaatttcat tttttcacct cttgtattcg attggttcta atgttatcaa
    41701 aaattttatc aaaaaggtag tctttatgaa aaaagaaaac aattattttc ctaattttat
    41761 aaagaaaaag agaataagct gcaagccttt caggctgagg gcttatcctc ttttcgacta
    41821 atctacataa tacatgattg caaacgcgtc tttaccagta tgcgtagcga taaccggatt
    41881 cgtatgcagt acagggatat gcatgtccgg gaataattct tgcaaaccct ctttgaattc
    41941 ttgcgccaat tcttttgcat ccgcatgtga aataccgatt tgtcgcacat ttggcaattc
    42001 tttcagttca tttttcaaat tattaaacca tttatcgaac gttttctttc ctcgcccctt
    42061 agttacaggg attaattcag aatgggcgaa attcatcacc acgcgtatgt tcaaaacact
    42121 agacagcaaa ccagttgttc ggctgattct tccacctttt accaagttat ctagtgtgga
    42181 tattccgatg tataattttg tattgtcttg tacttttttg acttcttcaa ggattttctc
    42241 tactgtttta ccttcttttg ctaattcagc tgctcgaatt acctgaaaag ataatccttg
    42301 gtcagtggta tcactgtcga taaccgttac tttcgttttt gttagattac tggcttgtct
    42361 tgctgcttct actgttccac tcaagccttt tgtcatatgg atcgaaatca cttcactgcc
    42421 gtcttctcct agctcatcat acatcgagat gaattctcca attggtggtt ggcttgtttt
    42481 gggcagattt tttgctttcg ccatcatttc cataaatctt tcgccgtcta gttggtcatc
    42541 atcgggatat actgttccgt cgatcatgat ggatagcggc atgacacgaa tgcctaaagc
    42601 atcgcgtaca tttttttcca tcgtacatga agaatctgtt acgattttta catttgtcat
    42661 tattttctct ctctctttct ttaacaagat gccttattca tgttaaacta catgtaagac
    42721 aatttctatt tttagtataa cagacaaata atgatttttc attaattaca cctagtaaag
    42781 gagccgtttt catggaaaaa acgaaattta atcgaacgta tgaaatatta aatgaagtgt
    42841 ttaatgcagt cacccatgga attgggactg gattgagtat cgcgggacta gtggttcttt
    42901 tagtaaaagg tgcccacttg cattcctccc tccatattgt ctcttatgct atctatggat
    42961 cgatgatgat tcttttattt ttaacgtcta ctttgtttca ttcattgatt tttacaaaag
    43021 caaaaaaggt gttccaagta ttcgatcata gttcgatttt tcttttgatt gcaggaagtt
    43081 atactccttt ttgtttgctg agtatccgag gatggctagg ttggacttta tttgtattaa
    43141 tctggttgtt tgcgattctt ggcattatat ataaagcgtt gacgttgcat aaacgggaga
    43201 gagtatcaaa agtatctacg atcatctata tttttatggg gtggctctgt gtcgtggctg
    43261 ctgttcctct ttatcactct cttggaatga ctggtgttat tttgatggta gcaggcgggc
    43321 tttcttacac gataggcgca ttcttttata gcttgaattc tatccgctat atgcatgttg
    43381 tttggcattt gtttgttatg ttaggtgcag gttttatgta cttctctgtt ttattcttta
    43441 cttaataaaa aaaataaagc tatggatggg acagctctaa ataacagcta gtctatccat
    43501 agctttttta tatcgtcaat tcgcctgtcc cgctttttac aggattctca ttacgctgat
    43561 acgtttcaaa ttgatgcgga taacgatttt tttcatccat ttctccttga ctagtattga
    43621 tcagtgacca atcagaccag tcaacaggtg gaaaataagc atctccatcg aatacatgat
    43681 ggatgactgt acggtataat atcgtacaaa atggcagaaa ttcttgataa acagctgacc
    43741 ctccagcgat gaaaaagata ccgtctgttt ctttttccag agcaagcacg tcttccacac
    43801 tatgcatgac atgcacgcct tctgctttat aggaagaatc tctcgtcaaa acaatcgtct
    43861 gacgattcgg caacggacgg ctacccatcc cttcgaatgt ttttcgtccc atcactagtg
    43921 tatttgcttc tgtcatttgt ttgaagaatt tcagatcatt tggcaaacgc caaggaagac
    43981 ggtcttcttt tccaatcaat ccgttttcat cctgtgccca aattgcagct aacattttct
    44041 catcctttct gattctaaac agcgatagga gctttgatcg ccggatgtgg gtcatatcct
    44101 tctaattgga tatcttccat ctcaaaatca aatactgact gcttttcctg attcaaaact
    44161 aaagtcggaa atgcgcgtat ttctcggctc aattgttctt tcatttgttc gatatgattg
    44221 atataaagat gagcatctcc taatgtgtga acaaattcgc caaccgctaa acctgtttca
    44281 tgtgcaatta ggtgagtcag caacgcataa cttgcaatgt tgaacggaac gcctagaaac
    44341 acatccccac tgcgttgata caattggcag cttagccgtc cctcttgaac ataaaattga
    44401 aacatcgtat gacaaggagg caaagccatg ctaggaacat cttccggatt ccatgcagaa
    44461 acgatcaatc ttctagaatc aggagtcttt ttgattgctt cgatcacttg tttgatttga
    44521 tcgataaagc caccgtcttt tgtttcccag tgacgccatt gatagccgta gatgtgtcca
    44581 agatcgccgt atgtttcagc aaaggaatca tcggttagga tcttctcgca aaaaagcttg
    44641 ctctgctttt tatattcttc attgaattca ggatctgtca aacatctatg gccaaaatca
    44701 gtcatatctg gtccattata gtctggactt ttgatgtagc gttcaaatgc ccattcatcc
    44761 caaatatggt ttttattttg taatagatag cggatattcg tatctccttt taaaaaccaa
    44821 agcaattcgc ttttgatcaa tccaaaaggt actcgtttcg ttgttaacaa aggaaaccct
    44881 ttttgcagat caaaccgcat ttggtatccg aataagctta atgtgcctgt gcctgttctg
    44941 tcttctttac gatgcccttc ttccaacaat tttcttccta agtcaagata cgcttgttcc
    45001 atcctttttc ctcctaatct tctacccatt cactcaagta ttcccaccgt gccatttttt
    45061 cttcaagttg tgcttctgtt tcagatacgt cgttttgcaa ttcttgtaat cgagtgaaat
    45121 tatctccttg atgattcatc tcttcttgga gcaatgagat tttttcttca agttctgcaa
    45181 tctcatcttc aatcgtttcc cattcttttt gttccatgta agataatttc ttcttttcag
    45241 caggttcctt gctctgtatt tttggtttcg ctttttcagc aggctgctgg gtctcttttt
    45301 gcttcagtaa ataactggac atgtttccgt aataaagttc ttgttttccg tttccttgga
    45361 atactaataa cttatctgct accttgtcca agaaataacg gtcatgggaa acagtgatca
    45421 cagcacctgg aaaacttcta aaataatctt ccaaaatcgt caatgttgct atgtccaaat
    45481 cattggtcgg ttcatccaat aataaaacat taggttgctg aatcagcagt ttcaacaaaa
    45541 ataaccggcg tttttctccg cctgaaagtt tgcctatcag tgtcccatgc ataaatcttg
    45601 gaaataaaaa tcgttcaagt aattctgcta ctccgatttg actgccatct gctgtttttg
    45661 cttcttcagc agcttcttgt aagtaagcaa tcatccgttt atctggtgcc atttcttcat
    45721 tttcttgtgt ataatacgca agatgaaccg tttcaccgat agacattgta ccgctatcca
    45781 ggggaattct gccagctaga atattaagca atgtcgattt tcccgcacca tttttaccag
    45841 taatacctag tctttcccga gattgaatca ataaatctaa atgttctagc agtgtttggt
    45901 catttatacg gtaactgcca tctttgattt ccagtacttt tttccctaaa cgttgtgtcg
    45961 ctaggttcag ctctaaatca tcttcttggt ttacttggta caagttctcc tttagatctt
    46021 cgaaacggtt gatccgtgct tgctgcttgg tgccacgtgc ctgtacgcca gccctcatcc
    46081 aagctaattc ctgtttataa agccgcttgc gcttttcttc ttgttctact tctacacgat
    46141 cacgttctgc tttttctaag acgtaagctt cataatttcc tttatactcg tataattttc
    46201 caaatgaaag ttcgaagatt cggtttgcta ctctatctag aaaataacga tcgtgggtaa
    46261 ccatcaatag tgcgccacgg tattgtttca aatagttttc caaccactcg atcgcttcat
    46321 aatctaaatg gtttgttggt tcgtctagta atagtaaatc gggttcatca atcaacactt
    46381 gcgccagact aactcgtttt ttctgaccac ctgataaagt actgattttt ttatctaatt
    46441 cactgattcc taatttttgc aaaataatct ttgcgttggt atctgtagtc caagcatctt
    46501 ctttattcat ttgttcttct gctttagcat aacgtttttg cacatcaggg tcttctccgt
    46561 tttcccctag ttcgatcaat gcttcctcat atgctcgaac agtttggatc aaggggctgt
    46621 ttccttgaaa gactgcttgg agaacagtta attcatcgga aaattcagct gcttgagaaa
    46681 gataaccaat acggtaatca gttggataaa acactgtttg ccgatcaccg tcgctgctat
    46741 cgataccggc aataatattt aagagacttg ttttacccgt cccgttcgtc ccaatcaacc
    46801 cgatacggtc tttttcgtgg accaaaaaag aaatctggtc aaacaaatct ttttcaccat
    46861 aagttttttt gaggtcagtt acttttaatt ctttcaacat gttccctcct tatcttggat
    46921 attgtatcat aaaaatagtg aacttcagga aaattttttt ggtatttgtt ctttttgtgt
    46981 tctcaaaaaa agaacaggac cgattcgatc ctgttctgat atgttttgtt ttttataaaa
    47041 cttgaaaatt tttacctttt tattttattg gactcgtttt ttttgacttt gctcgaaacg
    47101 caaatcggaa agaaaagtta tcagatggtt tgttcatcgt ataagattct aacaaattga
    47161 tattcctgcg atagctgttc gcagaaaacg tcgtgatttt ttcagcaact tcgtattcat
    47221 caatgatttt tctttcaaga taataacctc ttagcatttt tttcgtaaac agactatctt
    47281 gctggatcat ccacgaagaa atcaaattcc ccgagttcat ttttattcct tcaagtttgc
    47341 gttgctggat aaaaaattga accatcgttt catcataaat atcagtcaag ttatctaaac
    47401 tttcaataat caactgagta tttttttgat atgtctctct gatttcttgg atatcttcat
    47461 cactaataaa tgtctgacga tcagcatatc ttctttgcca aaacattttc ggatggagaa
    47521 cgattcgcat taacctacgg acaacaatga accaaaagcc gataaaagac aaaatctggc
    47581 ttgtgataga atgttcgaat cgagaaagaa aacgggagta aaaacgataa ccattagaag
    47641 aaagcttgcc cgaacgataa ctttcatcca atccatcccg ttcgatcgac aaaatcagtg
    47701 cttgtatttc ttgtacttct tgcttttcat catcggttaa atcttccaag tacagatcac
    47761 gtatccgttc ttgataattt tctatcactg cttcagtggc taaaaattct tttgtattac
    47821 gatcaatttc ctttatttct tttcgcaaaa cttcaacgac ctcttctaaa atcatcaaag
    47881 cattcaaatc cgtgcttttc gcttcctctg tttccgtcag cataggcaag acaatgatcc
    47941 ctatgaccaa agtcactaag atgacacccg ccgtcagaaa caaaagcaaa gaccgctggt
    48001 aaaacatcat attattgatt gaaaatggca aaataaaaat cgtagccaaa ctgactgttc
    48061 cctttacacc gccaaatgtt aagatcaaga tctcgttcaa ctgttttttg aactttttac
    48121 tgccatcttt gaatacataa aaaagactga tagaaatgaa tctgatcaca aaaagcatga
    48181 cagagattaa tacgataatc gctaataaaa gaccgtttgg atataaaccg tctccccata
    48241 ctggcgagaa cacttgcgtc aattcgattc ctaaaaatat aaatactaat gcattcagtg
    48301 taaaagcaat agttgtccat gtactgtggg acaagctcga caattctgca tcaaacacag
    48361 agattttcct aaaaccagaa gcttggagaa tacctgctgc cactgcagca atgattccag
    48421 atacatcaaa tgcctctgcc aatacatagg ctagaaaagg aagcaaaagt tcgatcagca
    48481 gataccctgt gacatcttgt gctgatgctt tttcgatcaa atgaattatt ttttgtttga
    48541 accagacaag caaaaagccg atcaaagctc ccccaatact agaaactact agactcatcc
    48601 ccgcgtttac tgctgaaaaa gatccggtga tcagcgcacc aagagcaaac tggaaggcag
    48661 taacaccaga tgcatcattc aaaagacctt ctccttccaa aatatgcatc gcctttttag
    48721 ggatattcac tcgtccagaa agagaactga ctgctaccgc atctgtcgga cctaacgctg
    48781 ctccaaaagc aaagcaggca gcaagtggga cacttggcaa caggaatgat aacgtcgcac
    48841 ctaccccgac aagggtcaaa atgactcctc caaatgccaa gaacaaaatt gtcccgaaat
    48901 ttttgagaat cgaagaaata tctgcttttt ctccttctct aaataacaat ggtgcaataa
    48961 tcataactaa gaacaattca ggttcaaaat cgattgattg tccccactct gtcagaccta
    49021 ataccactcc aaggaaaatt tggatcagtg gagctggaat cattggcaaa atgcggctag
    49081 ctatgttcga taaggtgatc gttactgcaa atacaataac taactcagca aattccatcg
    49141 tccatcccct ttatttttta ttttgtgtaa gcatttttaa aaattgttct tttttcttta
    49201 aaattttggt ttcgactact tcaacctgtg tttggttccc ctctaattca cactgtacac
    49261 gttttgactc caaacgaagc agatcatgtt tcagacgttc caactgacga tacatcaata
    49321 tatttctttt acgcaactta caaagtattt gacggcggtc atccatcgaa agggcgccat
    49381 agcgatcatg caacagtttt ttttgttgtt caaaactctc tctcattttc cagatctcct
    49441 atacacaaac ttccatcatt atagcaaagt tctttttgga tgaaaaatat ttcattgttt
    49501 catcgtttat tgctagttag aaatttccat aaatttttca acgcctcatt ctattccaaa
    49561 tagtatcaga tatcaagtaa aacttaagaa agataaaagt ttctgacaaa aggatgttta
    49621 ctttcccatt cctgcctttc ttgttctttt atcacaacaa aaaaatgggg ctgcgacaaa
    49681 aatcttgtca cagtccctta ttctgaataa acggtgtgga agagacagcc tatcagtagt
    49741 aataagacac atctctttca cagcctcatt tttgcgtaaa aatcgattta ttcgaaaaat
    49801 tccccgtata catcttctac acgttgatct ggattgatca cgatatacaa gttacctgtt
    49861 ttttcgctga tttttgttga ttgatattga ttgtctaatc cttctgttcc tttatctaga
    49921 tatgggaagt acacaagatc aggtgtgcca tttcggtaaa ggatttccat tcgctcgata
    49981 tcttcgtatt tcaatgcgcg attaaacatg cccatttcca gtccgcctag gttgatatca
    50041 tgtgtcgcaa ctgcgtcccc ttcatggaag atttcgattt taaatccagc acacggatgg
    50101 atttcaacaa attcactgcc attgattcgt ccaaaacttg ttgtgatttg tttgatccaa
    50161 agatcgccga tatgacggcg gttgatcgtc caggtttctc catttctaaa ataaaatttt
    50221 agcgctgtca tttctttact cattaaaaag actcctttat gatgtaattt attcttgtac
    50281 tacctcagtt tagcacaaat ttatgtaagt ggtcacatct tatgtttttt cttctaatga
    50341 cgtatctgcc cactttaagt agccaacaaa gctgagcaga tacagtctag tgttttttaa
    50401 atcaattttt ctttcgataa aaaatccaaa acctgttttt tatcattttt tattctttgt
    50461 tctacgacgg ctttttcagc taattgcaaa gcttcactaa cccacttacc aggttttttt
    50521 ccagtttctt ctagcaagat tttaccatct actgctaatt cgcttaatga cttgataggt
    50581 aaacgatcat aggattctcc tacggcatcc atctgaggtg tttcgtcaaa atagatcatc
    50641 aattcttcta cttgcagtgc atgttttttg cctaagaagt acaattcgaa tggttccaaa
    50701 gctccagttt ctcgttgtcg tagtccttgg acaagtgctt gaacgtcttt aatcatttgg
    50761 ttagaacact tccacgattt caaaaaggaa cgaatctcat tttcttttag atccagttgg
    50821 ctgatcaata atgcccatgc ttggctctct tctttcaatg ggacggatgg taattcagca
    50881 aaacgtaaaa gtgcttcgcc ttcttctttc aaaccgggac agcaaatgta gcactctgtt
    50941 tcaataaatg catggattcc cgcggcccgt tcatttccca agagcatctt gatgaattcc
    51001 acatttatac gttctacaga tattttacct aatagctcgt ggttttcttt gatggcgtag
    51061 aaggtttctt cctctaattt gaaccctagt tgactgacaa aacgcaaccc gcgcatcatt
    51121 cgtaaggcat cttcatggaa ccgctcatga ggattgccta cagctcgcaa gatctgttct
    51181 tctagatctt gcagaccatc gaacaaatcg atgatttctc catcttcttt caaagcaaac
    51241 gcattgatcg taaaatctct tcttttcaaa tcttctgcca acgaacgaac gaattcgaca
    51301 tgatctggtc tacggtagtc ctgataagtt gattccgtcc gaaatgtggt gatctcatat
    51361 tgttcatcat tttctaatac caacacagtt ccatgttcga tcccaatatc tatcgttttt
    51421 ggaaaaagct gtttgatttc ttctggaaat gcgcttgttg cgatatccac atcatggatt
    51481 ggctggttca gcaagatatc acgaacactt ccacctacaa aataagcttc atatcctgca
    51541 ttctctaatt ttttcagaac tggaattgcc ttttggtatt ccagaggtaa ttgttttaat
    51601 ttcatttttc caacctttcc tgcgtgtttc ttgtcctgag ataaagactc agttgcatgg
    51661 tgactgtttg acaagtccgt ttcagagtct tcaaggccag gaccacttca tcttgtttac
    51721 tcgtccttac gctcaaagcg attatggtct ctttgattga atttttccat gtttttttca
    51781 aaaacttcag ttaagtcgat attcaatgaa ttagccatga tcatcgtaac gaataaaaca
    51841 tcaccaagtt cttctgctac cgagttaact ggttcagaag cctttttgct tttttctcca
    51901 taagtgtggt tgacttctct tgccaattca cctacttctt cagttaatcg agccatctga
    51961 gctaatggag agaaataccc caccttgaat tgctggatat attcatccac ttcctgctgc
    52021 atactgtata aagaacgctt tttatccatc tttttccctc caaaactatc ttaccaaaac
    52081 tttaacgcaa atcctagata agagcaattg agaaaatcga atttccatgc tacatttagg
    52141 aaggaatttc taaatggaaa ttctgtgaaa atacataatt gaaagctgga attcatatgg
    52201 tcaaacgaaa aacagtaaaa gaagttcttt ttatcattat aggaacaagt atttatgcat
    52261 ttggtcttgt ttacttgaac atcgctaatc atttagcaga agggggagtc tcagggatca
    52321 ccttgatctt aagagcttta tttggtattg atccagctta tacgacttta ttaatcaaca
    52381 tcccattgat tttactagga ggaaagatcc tcggtaaacg ttccttggcc tatactgttc
    52441 taggtacact ttctttgtca ttctttttat ggatctggca aagggttcca ctagaaatca
    52501 atttacagca tgatctactg atcgtttctc tacttgcggg tttagttgca ggtgtaggaa
    52561 gcgggatcgt ctaccgcatg ggtggaacaa caggcggcag tgatattatc gctcggattt
    52621 tagaacaaaa ttacggcatc actatggggc gttccctatt ggcatttgat atcatcgtct
    52681 tacttgcttc attaacctat atcgacttga aacgtatgat gtatacgttg attgtttcgt
    52741 atgttttcag tcgtgtgatt gattcgatct tagatggcgg atattctgca aaaggtctac
    52801 ttgtcgtctc caacaaaagc gaagagattg caccactact gatgaccggt ctgcaaagag
    52861 gtgtgacttt cctttctgga gaaggcgcat tctctggtaa ttcaaaaaaa atcatctata
    52921 tggtcgttag ctctagtgaa ttaactgaag ctaagaggat cgtccacgag attgacgaaa
    52981 aagctttcct ttcaatcatc aatgtgcatg aagtggaagg gcaaggcttt acttatttga
    53041 agccacagac aagattactg aaaaaactat aagaaaaaag acaaagatag gctatgagga
    53101 aagattccac atccagctga cctttgtctt ttttagtact atactatttt taactaattg
    53161 ttatgttcac ttacccggtt acttttcttt tgtgtctgca aaaggatctt tcggttaact
    53221 tcatcagata atttcaaaaa agcatcccta tctccatctt ctagtgcttg atcgatttga
    53281 gcataaagca tttttagttt tgcctcttct tctttttctt gaaaatatcg ttcaattaat
    53341 tcagtatctt cttcactgac tgaagaatcc caagaagaaa atggattgtc ttctaagata
    53401 gatagatatt ctcttgtctg ccaagcattt tcgaatatac attccacata taaaggcttt
    53461 ttccaattca aacggatttc atgaaaaatc tggtctgtgt ccgtaaattc ttttccctgc
    53521 aaaaacaatt tcatgggttc cccttcaaca gatagatcac tgatctgcag tcctcgatcc
    53581 gcaaaattcg ccccttcaac aaagtggaca ttgcttaaaa tcgcttcatg attggcaaga
    53641 taattcaaga tccaaaaaac ttctcttcgg ctaaaagata catgattgac catccacgtt
    53701 aaaaaattct tcttttcccg tacatcaatt agcatttttc tcacctctct gttaggtcat
    53761 ctaataatga cagtgcctcc atatctcctg gttcaagtgt taaataataa gtcaataatt
    53821 cttgcgctct tttcagctgc ccttcttctc ttaagaaaaa ggcatactct ttcaagaaat
    53881 ctggttcatg tgatagttca tgataagcct gttcatagtg tacagctgca acggtaaagt
    53941 cttctaattc attataagca tgggctaggt tccattctgc ataaggatta gcagtttctt
    54001 ccatctgatt gatcacttgt atcacatctt catatctttc atcatccaag taaagattac
    54061 ttaaagtaag taatgtttca tcttgtttgt ctcctacttc taaagctttc agtaaaagtt
    54121 cttctgctcg ctgtctatca tgcagacgga aagcattttc cgaggccagg tgataaagtt
    54181 cgacttggta aggattttct ttgattcctt cttctaacac tgtttgtgct tcttcaatca
    54241 tttcttcttc ttgaagagct tgtcctagat atagatataa cgattgataa tgcggattaa
    54301 cttctcgaag ttcttccaga tagttgattg cctgctgatt ttctttcaat tgaagattcg
    54361 taaaagctag ctggaacagt cgatcatctg tcctttcttc tttcagtgct tcttctaaag
    54421 gtacgatagc tgcttcgaat tctccttgca tacttaagga ttgtcctaaa cgttcctgca
    54481 tcgagattcc tgaaatttca tttatcccgc ttgccaacaa tgtttcataa accactgctg
    54541 cctctttgaa acgatcaact gaaaaataca attcagctag cgcaaactgg atcaatggtt
    54601 catcaggaag caacccagct gcttctttca attttgcttc actcacttca gggattccga
    54661 taacttggta caaatcagct atcgccaata agctttgcgg atagtaatca ctttgcttat
    54721 ccactttttc caggtattca aaagctaagt cgatctcatt atcttcgatt gcaatttctg
    54781 ctaacgggat gttcagtccg tcattttctg ggtattggtt gatcagttgt tcaaaaatct
    54841 gttttgcttc gatcaaaaag ccaatagcca gcaattcttc gcctagttca gctaatatat
    54901 ctgctgggtc ttcttttaat gctttttcta aaaagatttg tgcttgtgac aagtcttcat
    54961 ctgataaagc ttgcaacatt ttttcgctat ttgtattcat ttcaattccc tcttatctca
    55021 ctgacgattt gttgaaatac cgtcattgtt ctcaataatt ctttttcgtt tggatgttgg
    55081 tatccgtcta ttatacctat tttttctaaa acaagtattt ttttgctttt ttctgccaaa
    55141 aaaagaactt tttccaaata ctccatcttt gaaatctgtt ccagccagtg gattggatag
    55201 ccaagcaagt ccagccacac aaaaaagttt tttagttgga aatcaaaagg atatgcttgg
    55261 agattccaca cgaaatgaaa catcattcct aaaaattttt tcatactagc agaaagtaga
    55321 tggccatttt cggtcagata aaaagcttgt tcaaacagtt taccataatt tgacaggttt
    55381 tctgcctcta attgataaaa atagatcatt tcttcgatca tcccggcaaa cggccgagtc
    55441 gttaattgct ttttatttgg atagttttta tacagatttt gcaaaaaacg atgatcacaa
    55501 atcattccgc aacagataaa agtcaaaaag tcaatctgct ttccgtccac ctgccgctcg
    55561 ctgattgttt gatcataaac gatgcgttct ggcagattga tggtttgcag cactacacga
    55621 tttggtagct gcaaaatcgt ccgctgcggt gttaatgctc ggcttagaga acggatcgat
    55681 acagggatca tccatagtga tgaatcaagg gttgtatgtt tttgaaaaaa acctgccaga
    55741 tccatgatcc cttcatttcc aaatccgatg ataaacatgg attgattttc gggatagcgt
    55801 ttgacgaaat caagcaggtt ctttaattct gttaaatgat tgcattgagt gttggcacaa
    55861 atataccagt cattgtttgc ttgatttgca aataacgggt tgatcttatc tgcaaacaaa
    55921 tcataatagc gctgattcgt taaaaataag attggctgat caatggaaag ttctcttagc
    55981 tgactgacta gcgtttctcc gtaaaacact ttcgtcaacg catcttctac ttgataatca
    56041 agttccatac gcatccctcc tcttcttatt tttattttac cattagtaag caaattctag
    56101 aaaagataag agcaaagctc acctcataac ttgcaaataa ataaaaatta aataaaatac
    56161 atgtgttttc tatgtatgac atacggattc ggaatctctg tctcttattt attccttttc
    56221 tgctaggaaa taaaaagaaa agcacttgta gccctagagc cacaagcgct ttttcaactg
    56281 tcttatttaa cagcgtcttt taatgcttta cctggtttga atgcaggtac tttgctagct
    56341 ggaatttcga tttcttcacc agtttgtggg ttacgacctt tgcgagctgc gcgttcgcga
    56401 acttcaaagt taccaaaacc gattaattga actttttcgc cgttagctaa agcatcttga
    56461 atagttgaaa atacagcatc tactgctgca gttgcatctt ttttagttaa atcagtagct
    56521 gaagcaactt tttcgattaa ttctgctttg tttgccatgg atagattcac ctcctccaca
    56581 agagatatga tagaaatatc atttagttaa aactttctga gtggtccaga agtttaaaaa
    56641 gaaatattga ttaacttcaa tattctgtta tcacgatatc atatgaaccg cttaatagca
    56701 aggtttttac caattttcac atgctttttt tagtcataga aacgtaacaa acgaaactgt
    56761 ctttttcttt tgaaaaaaaa acgtcgatat ggtaaaatgc ctattttctc ctacgaggga
    56821 taattcggat ggacgtccct tcaaaagtaa atgcttttct gatttgattt tctaagaaac
    56881 gttcataaga aaaatgcatc aattcctctt cattgacaaa aacgacaaat gtaggtggtt
    56941 tgacagcgac ttgtgtagca taaaaaatct tcaggcgttt tcctttatct gttggtgttg
    57001 gattgattgc tacagcatcc ataatgatat cattcaacac agccgaagag atacgaagat
    57061 tctggttcat acttacttgt tcgatcattt caggcagacg ttccaaccgt tgtttagtca
    57121 ctgcagaaac aaaaacgatt ggagcgtaat caagataccg gaattcatca cgaatctctt
    57181 gttcgaaatc acgcattgta ttggtttctt tctttacaag atcccattta ttcacgacga
    57241 taataattcc acgaccagct tcatgggcgt aacccgctac tcgcttgtct tgttcccgaa
    57301 tcccttcttc agcattcagt accatcaaaa cgatatcaga acggtcaatg gcacgcattg
    57361 cacgcatcac gctgtatttt tcagtatttt cgtatacttt tccgcgttta cgcataccag
    57421 ctgtatctat cattaagaat ttctgaccac tttcagaaac gaagtgggtg tcgattgcgt
    57481 ctcgggtcgt tccttcaata tccgaaacaa ttacacgttc ttctcctaaa atcgcattga
    57541 tcaaagagga tttaccaaca tttgggcgac caatcaaact aaacttaatc gtgtcgtcgt
    57601 cctcttcttc agtctcttca gagaaatact tcactgcttc atctaaaata tcaccaatcc
    57661 ctagtccatg gcttcctgaa acaggataag gatcgcctag ccctaaggaa taaaattcat
    57721 agatatcgtt tctcatttct ggattatcta ctttattgac tgctaaaatc actggtttat
    57781 tacttctgta taaaattttc gcaaccatct catctgcgtc tgtcacgcct tcgcgtccgc
    57841 tgactacaca aatgattaca tctgcttctt caatcgcgat ttctgcttga tgcttgatct
    57901 gatccataaa aggttcatcg ccaagatcaa ttccgcctgt gtcgatcacg ctgaattctc
    57961 gacctaacca ttcacctttt gcataaatac gatcacgagt tactccagga gtatcttcga
    58021 caatcgagat acgctcacca gcgatgcggt taaaaatcgt agacttaccg acgttcgggc
    58081 ggccaacgat tgcaattgtt ggatttgcca tattatttcc tcctcacaag tttccaatct
    58141 cacttagttt aacgaatgca ttgccaactt tcaagcatag attgtcaatt aaacgaagta
    58201 tttttattcc ttattgaaat actaatcgct tttcaaaaga aaaactgaga caaaagcagc
    58261 tgctttcatc tcagtcacag atacaaaatc aattattttt cagaatcatc ggttgctttt
    58321 tcttctactt cttctttcaa cgcatcacct aaaatgtctc ccatagtaaa tccagtattt
    58381 tcttctggta attcataaga ctcaacattt tttggttctt cttctgaagc tggtttttct
    58441 tctaaagctt tgatactcaa tgcaatacga tgttcttctg gatggatctc taatactttc
    58501 actttcactt cgtcaccttc atgaagcact tcatgtggtg tcgcaatatg tttatgtgaa
    58561 atttgagaga tatggactag cccttctact ccagggaaca cttcaacaaa ggcaccgaag
    58621 cttgtcaaac gtttaactgt tccgtctaat actgtgccaa ctggagcttt tgtatcgatt
    58681 tctgaccaag gtccaggctg tgtgtctttg attgacaagg aaacacgttc ttgttcagga
    58741 ttgatagaca acactttgac atttacatca tcattgacag ccaatacatc acttggtttt
    58801 gctacatgac tatgtgaaat ctctgagaca tggactagac cgtcaattcc gcctaggtcg
    58861 acaaatgcgc caaaatcagt aagacgtgca acacgtccac tgagaacatc tccctcatgg
    58921 atagttgaaa gaatttcttt tttcttttct tctctttcgt tttccactac cgctttatgc
    58981 gataagatca aacgattttc tgatggttcg atttcgatga ttttaaagct caatgttttg
    59041 cctttatagt ctgaaaagtc tgcaacaaaa tgatcttcca ccattgatgc agggacaaaa
    59101 ccacgtacac cgacgtcaac gactaaaccg cctttgacaa catttgtaac aggtgcttcg
    59161 atgaccttgc cctcttggaa atctctttcg atatcttccc aaactttttt agcatctaaa
    59221 cggcgttttg aaagtagata gctgccgttt tctttatctt tgccgatcgt actgataacg
    59281 actaaatcta atacatcacc gacttttact acttcgctga tatcttctac cggcaaagtt
    59341 gataattctt ttgccggaac gactccttca actccagccc cttcgattcc gacaatcact
    59401 tgtttgtctt caatgactaa aacttcgccc ttaacaacat cgccaacttt tacttcttgt
    59461 acgcttttca ttgcgtcttc cattgactgg ttgttctctt gattttgatc aaattctgtc
    59521 ataacacttg tcctcctaac caacattctg ccgtaagtac ggtactgttt ttagtttaat
    59581 tgattattca aaaaaaataa agcgatttcg ttcgttttcc ttgaaaaaac aattgttttt
    59641 catttttttt cttaatttaa aaaagaagat aacctttttt caaaacaaca gcttttattg
    59701 ctgcaacgac ttctggaatc gatttgccag tcgtatcgat acgaacagca tcctctgctt
    59761 gcttcagcgg agagacgtcc cttgttgaat cataatggtc tctttcctgt atctctttcg
    59821 tcagtgtttc aagatcagtc ggaattcctt tttcttggtt ctctttgaaa cgtctttctg
    59881 cacgctcact tacgcttgct actaaaaaga ttttcacttc tgcattcggt aatacagctg
    59941 tcccgatgtc tcttccgtcc atgacaacgc caccgcgttc ccctattttt cgttggacag
    60001 caactaattc ttctctgact tttccatgtg cagagacttc agaaacagct tttgtgacat
    60061 ctggttgacg gatttctaaa gtcacatctt ttgatgctat gaatacatgc tgtccatctt
    60121 cttgttgcga aaaagagata ggatactttt tgatcagcga aactagccct tcttcatctg
    60181 aaaaagatac attgttcgta atagctaaat aagttactgc gcgatacatg gcaccggtat
    60241 ctgtataaat ataattcaat tcttttgcta atatcttggc aacggtactt ttcccagatg
    60301 aagcaggccc gtcgattgca atactgattt gtgtcatgat ataactcctt tttctcagaa
    60361 aaaaagccgc aaagcgcggc tattattatt taattcttaa ttcttgacca gggtaaagca
    60421 taaagttgtt tggatctaag ccattcaatt caaacaattg atcagtggtg atccctgcac
    60481 gctcagccac ttgttttgga ccttcgcctg cttgaacagt cgttgttgaa ccggctgcag
    60541 ctgatgaaga aggtgttgtt tctgctgcat tgctgcttga atcccctgct tgataagttg
    60601 cctcacttga ggaagtcggt gttgtctctg ctgcaatact gctttctgac gttacacctg
    60661 tatcttgaga cacagtagat tcttccgcga ttgtactaga ttctactgtt gaagtctcag
    60721 ttgactcctc ttttgttgta cttgtagaac tttctactac tgatgtcgaa gtttcagaag
    60781 aagttgctgc tgttgcattg ttgcttgatc catttctgat ccagaaataa gcacctgctg
    60841 gaatagcgat acataagacc agtaaaatca aaaatagcga aagaaataat gtatttcctt
    60901 tcttttgttg tctctgagaa cttcttgatg aaacttcatc atctgtatcg tagattggtt
    60961 gttcccatgg ttcttgtgtt tcgttatttt ctgtagattg atgtctatct tttctgctca
    61021 ctgttttacc tcctaaactc tatcgtgtgt attataccat aggaaaaagt gtcttgtcct
    61081 aaaaaatcaa tgttccatgt tttttttaaa taaatttagt aaaatcgttc cccaatgaag
    61141 ttgttcagtc ttagaaaaaa gcttcctctt tggcagaagt tctgcttttg ctccatcaat
    61201 atcacaacaa ttctgcggct tttcggagag tttttcgcca aaataagcta agatgaattt
    61261 tctgcggcag ttttcttcat taatatagcg aagcatctgc tgcaggcgga attctttttc
    61321 tttttcctga cgtttgagcc gttccaccca attttctggt ttttcagact gctggatcag
    61381 ctccatccat tttttttgca gctcatcaaa gggagcttgc tctgtggcat attccaaata
    61441 aagctcaaaa ctttgtcgct gttctctaga aagttgatta aagaaataat ggatacgttc
    61501 atccccactt tgataaaaaa gaattgctgc actttcttcc tgatctctgc ctgctcgacc
    61561 gatttcttgt acatagtttt ctagactgtc tggcaaatca taatggacca cataacggat
    61621 atcagattta tcgatcccca taccaaatgc attcgtagca atgagaaact gcagctgatt
    61681 ttttacaaac tgctgttgaa gttgtcttct ttgagctgca tcaagaccac cgtgatagta
    61741 tccaactgta aaacgttccc tgaataaatg atacaatcgt tcgacttctt tttttgttgc
    61801 acaataaatg attgccgctc cttgtgctct ttccatgaag tgttcaagtt cttgttcttt
    61861 ttgctgcgtt ttccgaacaa aaagcgagat attttgccga ttgactgatt gtctgatctc
    61921 ttttggtggt cgatcaaata gtacatgacg tatatctctt gctactaaat ctgttgctgt
    61981 cgccgttagt gccagtgtga ccgggtttcc taaaagcttt cggatttttc ctaactgttg
    62041 atattctgga cggaaatcaa ctccccattg agacacgcaa tgagcctcat ctactacata
    62101 taacgcaata ttttgttttt tcagatgctc taaaagagaa ggattagtca acatttcggg
    62161 actcaaaaac aaaaatttat attgcgatag atgacggagg acgtatcttc tttcagattg
    62221 cgaaagtaaa ctattgaaag cagctactcg tttctcccct cgtttttgta attgcgtcac
    62281 ttgatcttcc attagagaaa gcagcggtga cacgatgatg accagacctt ccattaaata
    62341 ccccgtcaat tgatagcaaa ggctttttcc cgttcctgta ggcaaaatag cgagagtatc
    62401 ttctccatca agcaacgcct gaataatttc ttcttggccg ggacgaaatg aatcaaatcc
    62461 aaaatatttt tttaattcat ttattaacat tctgtatcgc ttcctttctc aatagataga
    62521 tttgatacaa acgaaattct ccataatcta attgtccatc tacattccat tcgctaaagc
    62581 gccactctcg cacggaatcc ttatttggtt ccaaacgttc gattgtttct gcagagagaa
    62641 tccactcgta tggaaaatca tcaaaaaaca aggcccactc aataagatga tctgttactg
    62701 ttcctctttt taaatgacgg attgccatga tctggtcaat tgtctgacca ttcataaaca
    62761 tctgcttggt gatcatcatg ctttgattga aattttgctg taataatgaa tcgatcaaag
    62821 cgtgccaaag cgaatctggc cgtttttcga tttgtgctaa caaaaggtgg atacatctgc
    62881 tttgttgcag ataaaccgct gactcatcat tgttttttgc cagctgataa ggaagcagcc
    62941 ctgttcgctc atttccagat aattggttag ctaaaaaatc tgctgcttct tctggtatct
    63001 ccgaaaacag ctgcaccaaa ctctcatacg cagtatcaat caaaatttca cgtggcaatt
    63061 ggctttcact aagccatttt tttagttgga aagtataaaa aggacttgtc tctgctggaa
    63121 gatagtcttg aatacccgtt gccagattag aaattacttg aacagcaaat ttaatgagcc
    63181 gccaactagt ttcccctgtt ctgccatagc ggtcaaaacg caaaccagta tgttctattt
    63241 gatgttcgga caacatatca gcccctgcag gcgttagctt tgcttcattt tcatttattt
    63301 cgatccaacc ttgctgcgca attttttgca aaatttgata aaacttatcc tgcttcaatt
    63361 ctggaaaact gttatggata aacaaaagtt cgtgggtaaa tccataaata agtactgaag
    63421 tcgttcgttt tcccacaagg agttggtaaa gagaactaat ccgcagcttg tgtcctgatg
    63481 aaaatagcga taaaataaaa acaatcatat tattctcctt aagttaggat ggttagaaat
    63541 gtcactacta tgtaaacttg tacctgaacg ctgtattgca tgcggtcttt gtcaaatcga
    63601 agcgccagat attttcgatt atgatgaaga aggaatcgtt ttatttgccc aagaaccaga
    63661 ggctcatcaa cagttcgtga tgccggaaga agaaacatat gtaaaaaaag cgtatcaaaa
    63721 atgtccagtt cgagcgattt tattagaaaa taaaatataa atataaacga aactttaaaa
    63781 acgtacacta agttctctaa acttgaaaat aagccgggat ctgtttctct tgttccgtga
    63841 aatcccgact tattttgaaa gattcatttg ctatctatag ttaattgact agttttttca
    63901 cggaccctat aggacccatt tatattattt caactttttc agccagtttt ccaatgtatt
    63961 gacgatcaca gtttgctggt ctgcgttaga aatttctgcc tctccatctc ctttttgctc
    64021 accatagctg ccaaaacctc catgatttcc gccattgatt gatacatact ctgttctttc
    64081 cggtaaatac tgcttagctt cttgataagc ttcctgattc aatactttat cttttgtcgc
    64141 cgtgatcgat aaaacaggaa cagctgattc tgtcaatgtt ccttttttgt cgggataact
    64201 tgccatgaag aatacccctt ttaaatgttt gtctgaatga ttcttattga cataacgact
    64261 tgccattacg ccacctaatg aatggccacc gatcacataa tcggaatttg gaaaatcttc
    64321 tttgacctta tccgctttgt ttccgcccat cactgctaga tcaagtggca ttttgacaat
    64381 agcgactgaa aagccgtttt ttgctaaatc ttgcgcccaa atactataac tttctggctc
    64441 tacgagagca ccaggataaa aaataagtaa tggagacttt ccatgattct ttttctctcc
    64501 ttcaaaaaat aagtaatctt ctttgttttt tccttctttt accaacactt gcgcttctga
    64561 cgatggttcg tacgtatttt gctgtatata gtaataaccg gctccaccga gtaatcctaa
    64621 aatgatgact aagccaatta gtattcgtct aaatattttc actttctccc accttttcta
    64681 tctgagtgac ccctttttct taatcaagta tgattatacc ttaaaaaaat aagagagaaa
    64741 tgcaaacttt ccagcatcaa ataaaaaaag acggaatatc catttgaata tccgcccttt
    64801 ttgtatgttt atttttattt agcacataaa cgatacacag cttctgcata aatttccatt
    64861 gctttataca tactacttaa ttcccatcgt tcattcgcct ggtgcataaa gtcaggagta
    64921 tcagggaaca tcgcaccgaa tgccacacac tggttcatcg tacgagcaaa agtagcgccg
    64981 cctgatacaa acggttcagt catgtctcca gtaatatcgc gatatgtccc caatagattt
    65041 ttcactaact cactgtctag tggcacgtat aatgaatcaa ggaagtcaaa ttcttcataa
    65101 gtcaacccat atttttctgc tgttttagtt aatttagcta ctaaatcatc tttcttgaat
    65161 gtaacaggga ttctcatatc tacaccgatt tttgtttgtt ctggtgtgat ttccaaactt
    65221 gcaaagttca tcgttagctc gccggattgt tcatcttctg ttttgcccac gacagcttca
    65281 ccagttgcat tttcttgaac taattttcct aagaaattga ttgggccaaa atcaaatact
    65341 tctgaaagag caattgccag acgagaaata gcattcactc cttgtgctgc atctttcgcg
    65401 tggatacttt taccaagaac gacgatgcct tcaccttgtt cttcgaaatc gaattcgtgt
    65461 tttttcaatg cttcttttac ttcagaaagc ttttctccag agtaaggagc tgcatcagga
    65521 acaacattca acgctcctcc agcttttaca gaaaactcgt tcgttcctgg tcctgtcaag
    65581 taagcttgca ataagccttt ttctgcataa attaaaggaa attcagcatc tggcgcaaat
    65641 ccttgcgtaa ttccttcttc tttttcgtta tatttttcta aacaacgcca taaattttct
    65701 tcatctgtac caaagataaa acgaatacgt gtcttgaatt ccacgccagc atcaatcaaa
    65761 gctttgacgg catacattgc cgcaatagaa ggacctttgt catcttggga tccgcgacca
    65821 actaaccagc cgtcttttat agttggatcg aatggttttg tttcccaatt attttcgtcc
    65881 cctgctggaa caacgtccat atgacacaag ataccgaata attcatctcc agagccaatc
    65941 tctgaataac cgtaatagcc ttctggatct ttaaatgttc taaatcctag cttttcactg
    66001 atttccaata ctttatccaa agcttcaatc acttttttac cgaagggatg tccttgtcct
    66061 gaatctgctt catctagtac ggaaggaatt cggatcaatt cgctcaatga ttctaatgct
    66121 tgttcatgat gttgttctgt cacaaatttt ttcatgatat tatcctccta atatgttaaa
    66181 aagggtcatg tcaaattcct ccgacacaac ctcttcttct caaataatga cgttttaagc
    66241 ctgctccatc agcaagcaga atgttcttaa caaatgatga aagaaaaaac actcactgaa
    66301 tggagctatt gacttatcca cgtgcttatc gatagccgtt tatcggtttc ttcattctta
    66361 tgatagacct tgtacctgta tttgtctagg tttagaacat tgctgctaca cctaggatca
    66421 cacagatggc tacaaataat atcgcaatta atttaccggt aaatttccac cacactgaaa
    66481 catcgaaacg agcaattgct acagcaccca ttacgatagc agatgttggt gtaattaagt
    66541 ttactaaacc agatgcagat tgataagcag tgattactaa atccttaccg acgccggcaa
    66601 attcacccat aggtcccatg attcccattg ttgcagcagc taagccggaa gttgaaggaa
    66661 tcaagaatga catagggata tagaaaataa atgtaataat gatgaataca cttgaagata
    66721 atgaacttaa tccttgttcg ccccaatgta agatggtgtc tgtgattaat ccattgttca
    66781 taaccacttg gataccacga gcaacagcta ctacgattgc tacaccgatc aaatcagaag
    66841 caccagctaa aaattcagag acaaattcag actctttcat gccataagtg attgctacta
    66901 cgatggacat tactaagaat aacatagtaa tttctgggaa gtaccagtca cctaatggaa
    66961 gcatgctttt acctagaacc gtacctagta ccggaaggtt tgttaaccag tttgtcaatg
    67021 attcaaaaat cgtgaaattc gcattcaagg ttgtccaagg aatcaaactg atgatcatga
    67081 taccaaaagt aataaagaac aatacattaa catgtttttg ttttttcgtg attacttctt
    67141 gacgaccgat tgcttcaata tcgaaatgct tcatatcttc tttacgttgg ttgtatacta
    67201 atgattttgt tggatctttt tcgatctttg atgcataacg atacacatat acaatagaaa
    67261 tagctaacaa aataacgaac atcaagaatc gaagaccaat accttcaccc atcgaaatcc
    67321 caacagcttg tgaagctacg cctgttgcaa aaggatttac cgttgaagct agacagccta
    67381 cttgagaccc tactaatacg attgctacag ctactactgt atcaaagcct acagccatca
    67441 tgactgggat cagtaaagca tagaatggaa tcgtttcttc tgccattccg taagtagagc
    67501 cgcctaatgc aaataacagc atcaatactg gaataagcat tttttctttt cctttgaatt
    67561 tcttcacaac tgaagcaatc ccggcatcta gtgcccctgt tttgttgata atacctaaaa
    67621 atccaccaac aaccaaaatg aagaaagaga ttgggattgc agcaggtgtt tctttagtta
    67681 gctcccccgc tggtacacct agcatcccat tgattggcgc catgaaaata tcccacagcc
    67741 cttgaggatt ttgttgtact cgttcatatg atccagcgac gatgttgcct gcatcgtcta
    67801 cactatagtg cccagctggt ataaaccaag taagtacagc gattactgca ataataataa
    67861 ataagaccgt atacgctgaa ggcatttgaa attttttctt ttttgtttgt tccatcttct
    67921 tcttcctttc ttttccgtta gagacaacaa ttttggctct aatgttattt tatcaaaaag
    67981 agtatcagaa caaaaataat aacacgcatt ttgtaaaact tttgttcaaa aagttcgttt
    68041 ttccctattc cctcctcttt tttcaggttt ttaaagcttt cttctttttc attgtagcgt
    68101 ttcctttttt ttataaacaa acattttcgt cttttaaaag gagaagaatt tcacatttgc
    68161 aaagaattga ttgattttta tgcataaatc aaaaaaatac tcaaaacaaa caaataaaac
    68221 gtttacatta ttgcatgtct tgtatttttt tccaaaaaaa aagaccaaga aatttcttga
    68281 tctttttgat atttatttga ctgctgtatg acgttgttcg aactgatgtt gttttcgact
    68341 taaccatgga agaagttgcg catgcagcac taaaaagaca gcactcacga tgaatccttt
    68401 gatcaagttg aaaggaacga tcccaatcag tacatagttt gctaaagaca tgcccagcat
    68461 ctgtgttgcg ttcagcccta aaaacattaa gtaaagaggc gtaataacga aataatttgc
    68521 gatactcata aaaatagtta gagcgatggt tcctgtaatg acacctaaaa atttgtttct
    68581 tcctttatgc tgtttcttta cactaaagaa ataataaatc gggaatgtaa agatcgttgt
    68641 tgataagaaa ctagcagtgt ctcctaccaa attatccgga gaaaaacctg tagtcagcag
    68701 atgtaatact gaacgcaaga acgctgttgc aactccggcc gctggaccga ataagaacat
    68761 gctgatcaat accgagatat cactaaaatc gatcttcaaa aaactaaaag ccggcatgat
    68821 cggaaaagca aaatactgta aaactaatgc gatcgcagca aacatcgcta ctgcaaccat
    68881 tttctgtaca cgggtgttct tcatttgaaa tcctcctgtt aggactcctc ttcagcgaac
    68941 tttttgacgt ttctctccaa atgaaaaaac tctattttcc agggaaaata gagttagagt
    69001 tatttgatca agcgtcgtca aataagctct atcttcttta tccagactat actgtcggta
    69061 tcggaatttc accgattcag ctattttttt gcaaaatagg tcgtggacta taaccaccgg
    69121 tcgggaattt caccctgccc ctgaagacga accttatata atttttgttt acatattcat
    69181 tatacatatc tattcaaaaa acgcaacatc taacacttat aaaaagtaag tgttcatttt
    69241 gagtggttca gcaaactgct gacttctttt ttgttcagtt cacggtaatc cccaggacgt
    69301 aggccttgta aagtcagatc tccgtatttt tcacgtttta gtttttgcac aggaagacca
    69361 actgcttgaa gcatattttt cacttgatga ttacgtcctt cgtggatcgt caattccacg
    69421 atactgtggt ttgtcttagg atccactgat aaaatttgga atttagctgg agatgttttt
    69481 cgtccttcga tctttattcc ttttgtcaaa ggtgcaagca tcgattttgt agcgatccct
    69541 tttacctttg caacgtaaac tttatccact tcatgttttg gatgtgtcag gcgctgagca
    69601 aaatctccat catttgtcag tagcaagatc cccgaagtat cgtaatccag tcgacctaca
    69661 ggatagatac gttcttttac catcggcaaa agatccgtaa caacttttct tcctttgtca
    69721 tctgcaacag cagaaataac tcctttaggt ttgtacaata aatagtaacc gtattcttct
    69781 tgataaattg ggacttcatc cacttccaca gtgtcatgtt tcccaacttt tatccctaat
    69841 tcccttacaa cttgtccgtt tacttttaca cgtcctgcaa ggatgaattc ttctgctttt
    69901 cgacgagaag tgatgccagc gtgggcaatt actttctgca atctctccat tacaattatt
    69961 ctcctttatt cattccatca aagaatagat ctggtgacac gtcttcttca agtgaaattt
    70021 ccatttcttg tgtatcaggc agttcttcta atgatttcaa accaaaataa tctaagaagt
    70081 agccagttgt tccatataat atcggccgac ctggtccttc tactctacct ttttcttcaa
    70141 tcagtttatg ggcagctaga cgctgtaccg ctcctgaaac ctgaactcct cgaatctgct
    70201 cgatttcagc tcttgtgatt ggctgtttat aagcgatgat tgctaaggtt tcgacggcgg
    70261 cttgagataa tgtgtttgat gtcccttgcg catatcgctt aagtaaggga gccagctctt
    70321 ttttagtcgt taatacataa tggctttccg tttcaaaaat atgcaaagct gagtgcgagt
    70381 tttgagtgta agattctttt aattctttca ctaaacttgt gacttctgct tcgctgagat
    70441 ttaacagtcc gcttaattct tcattactga tcccttcctc gccaacaata aaaagaaggg
    70501 cttcaagttc acttaatttc gtcatgttcg gtatctccta ctgctggata aagcataatt
    70561 gattcatagt tttctttttg ttgcgcaatg atctgccctt ttttcatcaa ttctagcaaa
    70621 gccataaaag tagtgacaac ttcactttta gaaggtgact caaaaaaaga atcgaaagta
    70681 cagccatgcg catttctttt tatacgctct tcgataaata ccattcgttc ttcgatcgtt
    70741 gtgtcatcgg gcgtgatcgt tttttccact ttttgagaaa atttcttacg ttctaagatt
    70801 ttctgcatgg cacggatcaa atcgattttt ttgacttgtc ctcgcttcaa cggcttttca
    70861 gcatccgcta acccatcgat gttcataggt tcttttgtgt aataaagact tcgttcctct
    70921 gctttttctg tcagtctttc agctgcatat ttatatttac ggtattctaa aagctgagtg
    70981 accaattctt ctcgaggatc ttcttcccat aattcttcat cgtctgtgac gaattcttgg
    71041 acaggaagca atgtcttgct tttgattgcc atcaatgtag cagccatcac taagtattct
    71101 cctgcaacag ctagctcgag tgttttcatt gtatggatat aattcatata ttgctccgtg
    71161 atcgtagcga tcggtatatc atatatatcg atttccattt gctgaatcag atgaagcagc
    71221 agatcgagag gaccctcgaa tacatctaat ttaatattga tctccgtcaa ctcattcact
    71281 ctttcttctt tttctttgct agccattttc caatgtaagg ctctgtgatt tcagttgcac
    71341 ggatggagac atccgggtac ttttcctgta attcatctaa catttgaaag cccatattct
    71401 caccgcgata agacggattc aaagaaatgt catggatgat cagctgatcg ttcgttgccc
    71461 agtaaatacc aataatccct tgaatgttgg ttgaaccttc tggcgtaaag aaaaaaagtt
    71521 cataatcgtc ttcagattcg tacgtatcaa tctccttcaa caaagaagtt ttacctgtca
    71581 gtttcttatg gaaactcaat agtcccatag caattttacg gttttctttc cggtaatgtg
    71641 ttaacatctt ctcaccttcc tatgactaag cccttggaaa atgctgctta taaacatccg
    71701 tcattctttt cttcgtgata tgtgtataaa tctgagtcgt agagatatcc gcgtgaccta
    71761 acaattcctg tactgtccgc aaatcagctc cattttctag cagatgtgtg gcaaagctat
    71821 gccgcagcgt atgtggtgtt acttctttgt aaatcccagc ctctcgtact aactgcttca
    71881 gatttttcca gattccttgc cgagaaagac ctttcccatg attattgaca aatacatgca
    71941 tttcagatgc gtcctttaca agtaatggac gtgcttcgtc taagtagcgt tccagccatt
    72001 ggatcgcata atcacctaaa ggaatgatcc gctctttatc tccttttcca actgtctgta
    72061 ccagtccaag agaaagatga agatctccca atttcaatcc aatcaattca ctgacgcgca
    72121 tcccagtagc atacatgact tccaagattg cacgatctct tatccctaac gtttttgtcg
    72181 tatcaggtgc ttcaatcagc ttttctactt ctgtcagagt caatgtactt ggtaatttct
    72241 gtgctttctt cggcgtatcg atatgttgca tcggatcatg atcagtgata cgctcttgcc
    72301 gtaaaaactg atggaatctt ctgagacttg agatcatccg agtaacagtt gctgtcgctt
    72361 ttttttcttc atgcaacttc tccagaaaac ggatgactaa aaagcgatcg acatcctgcc
    72421 atgaagcaat tttctgctcc tgtagaaaat gcaagtactg ttccaaatca cgttcatagc
    72481 tttgtcgtgt attggcggac aatccccgtt caatattcaa gtagtggaga taatcgttga
    72541 tttgctcttt cataataatc cccctcatgc ctctctatca tatcagatac cgcttcattc
    72601 tgatagtctt tttccataat ctgagcaaag aaaaagccgt ctagacactc agacggactg
    72661 gtttcttttt tctttttcat agcattcctg acagattcca tggaacgtta gccgatgatc
    72721 ttttactaaa aaatgataac gttcttctac tacttgctcc acttcaagta aaagatcctc
    72781 ttctacttcc tcgatcgtgc cgcagttcaa gcatagtaaa tgatgatgga aatgtttggc
    72841 gccttctttt ctcaaatcat aacgggctaa tccatcatta aaacttactt tatcgacaat
    72901 tttcaattct gtcaagattt caagggttcg ataaacagta gcaagtccaa tttccggact
    72961 cttttttttc actaaaaaga agatttcttc tgcagataaa tgctctttct cattttccaa
    73021 aagcacaagc agagtagctt ctctttgcgg tgtcagctta aaccccgctt catgtagctg
    73081 ctgttttgtt tttttcatcg ccgaaatagc attcatgacc atttactcaa ccccaacaat
    73141 ttataataat tacaaataaa aaaagatata acactatgtt aattaaaatt attataagct
    73201 agttaagaaa aacatgcaag ggattctcaa ttagattttt tgactagttt tgtcacaccg
    73261 ttttcttgtg taatcaatcc ttgtttcaaa agattaccta atgcgcgctt aaatgctcct
    73321 ttgctgatac caaaagcttt catgatttct tctggatccg atttatctgt aaagttgatt
    73381 tgctgatctg cagaacgttc taaaatggtt aaaatcattt gtgcatcatc tgatatagct
    73441 tcatatgctc ttggcttcaa tgaaagattc agtacaccgt ctggtcggac accaatcact
    73501 cgacctttta tctgctcgcc tagacgaggt tcattatatc gttcagaagg atggataaac
    73561 ccaagataga aatcttccgt taaaacgtac gtacctgtta atttcaagcg gtatgctgtt
    73621 cctatcacat ctttgttttt catttcttct gttccatatt tgcttaaaga tttgaatatt
    73681 ttttcatctg ctaaactgcc ccaaatacgg tcttttgcat caactctaag ggaaatcatc
    73741 aagcgatccc cttttttagg ccatagctct gtcattgtcg gcaattcatc aagagatacg
    73801 acaaagtctt tatctggaag accgatatcg acaaacgcac ctaaatcttt tcgtgtagca
    73861 gtaacgattc caaaagcgta atgaccgata cggcttttag gaatttgtgt agtgatccga
    73921 ttttcatgtt tttgattttg gtaaccgaat ccttcaactg cttcaccgat tttgtgttca
    73981 ccttctgatt tgcttaagcc aaaggtttgt ccgttttttt ggacaaagta gtttttttca
    74041 ttttcatcaa taataatacc tgtaaatata gttgctaata aatcgttcat ttttttctcc
    74101 ctctatagtg aaaggttttc ttaatacatt tctttgctat cataacataa tgttatctac
    74161 ttgaatagct gagccttggt ttggaaaggt gaaaaaagga gtatgacaac agttgtgtca
    74221 tactcccctt tttcgaataa acggtgttaa acggcaggct cacagcctct ttcatttgcc
    74281 taaaattaat tgctcccatt tcctccgaac catccagttt tacagttgat ggttacgatg
    74341 taaaatggca aagcactttc tccaatgcct ttcatcaatg cagattttgt tgaagtggca
    74401 tatagattat aatagccttc cccattttcg attctggctt tttctaatct gtaacctcct
    74461 tcaacgatat atccacgttg gatacatgta gcaatcactt tgctttggac acctggtgcc
    74521 cacgtccatg ctggattaga tgcatcggca atatcacttg ctctggcaga tttgattggc
    74581 tgattcgctg agtttgaaga ggaaggggtc gaggatgccg cttcttgctg tgctgcttgt
    74641 gcgaccgcag cttgttgagc ggcttgagct gcagctgctg cttgagcggc ttgttttgct
    74701 tgttcttcag ctgctttttt cgcttcttct gcttttttct tttcctcttc ttcttttttc
    74761 tctttatcag tgagcatctt atctacttgt ttcaattgtt cattcaactg agcagataga
    74821 tctgtatttt tcactttttc tactgcttct tttgccgtct tgtattggtc gcgtgttgct
    74881 gaatccacta cttttccgtc tttaaagact atagctgttt tttctttagc tgtttgcaat
    74941 tcagcatatt gatttttagc ttctgtttgt gcttgttgaa tcaattttcc aaaatctgtg
    75001 ttatccgttt cgattgcttg gatctcttta tctgctttca acttgatgtc atctgctaga
    75061 tgatcatcga cgatggcagg tgctatgaac cactcattca ctttttggat atctcggatc
    75121 ttagattgga tatcttggta agttgtttct aactctgaat atcctttttc attcttaaga
    75181 ctggataaat cattttttag ttttgataaa tcttgatgaa tcatatctgc acgaataaat
    75241 tgatggtgat catctgtata aaaggcagca agtttctcat gaagttcttc catttgttgc
    75301 tgtctttttg cttctgctgc tacttcggct tctacttttt gatgatggtc ataataagcc
    75361 cagcttcctc caccgagtag aagtactgct gctaaaacga gataaggtac tttttttgat
    75421 tttttctttt gcgctttatc tggatctgtt ttttctaagt ttgattcttg atgtgttttt
    75481 tcagtatctg gcacgattgt tattgatttc gcttctgctt caaacagctt aggctggttc
    75541 tcttcttttt ctatttttgc ttcaagatca gtaccctctt tgcttacaga ttgattttca
    75601 gcatcggatt cactatttat ttcatcgggc tctgttgact ttttgtctgt gttttcgagt
    75661 atttcttttt tctctgcttc cggcagttta ttcgtttttt ccttttctaa ttgtttttca
    75721 gtaaatactt cagttttttc tgtgatatcc gtttttacgt cttttatttt tactgtttct
    75781 ttacctgtgg cgttttctct atcagagtct ttttcagttt cttgttcctt ttctggctct
    75841 actttgtttt cctgtgcaat tttttcactg atcattttga gcagctcttt cgcgtgctct
    75901 tcttttgtat cttcacgatg tgctttgata taagcggata gtatcgaatt ttcttcctca
    75961 ttatcgacga tttctttcag ttcagctact cttctttttt gttttgattc aagcgtttct
    76021 tcttgattct ttcctgattc ttccgaagtc tcatgaacag ttgctttctt ctgttcattt
    76081 ttctctatat tagttacttg atcgtgagca ggtggttctt cgtcttctgg ttctgctttt
    76141 tcgaataatt ccattacaga ttctagaggt aaatctttca attccgacca ttcgattgga
    76201 tcgtttaatt ctgtatcagg aaagactgca tcttcagttg atttatcctg catagctgca
    76261 tctgtatttg tttcttcaat tgattctttt atttgctgat cttctgcagt tatttgatga
    76321 ccgcagtctg gacagatagt attctgctcc atttttttcg atccgcaatt tggacatttt
    76381 ttcatcactt agcgatcggc tcctttacta ggtttacgct accatttaat ctatcatatt
    76441 ctatacgtca cgccaatagc ttatttttag gatttactta aaaataatga atgaatttcc
    76501 ttcctataga aaaaaaagct tgagactgcg tagtctcaag ctttttttct tttaaaataa
    76561 accaaacagt tttactgatt tctcttctgg tcaatagtcc acgcttattc taagaaatct
    76621 tttaattgtt ttgaacgaga aggatggcgc aattttctta atgctttagc ctcgatctga
    76681 cgaatacgtt cccgagtaac accaaatact ttccctactt cttccaatgt tctcgtccgg
    76741 ccatcatcta aaccaaaacg taagcgaagg acattctctt cccgatcagt caatgtatct
    76801 agtacatctt ccaattgttc ttttagtaac tcataagctg cgtgttctgc tggacttgtt
    76861 gcttcctggt cttctatgaa atcacctaag tgagagtcat cttcttcacc gattggcgtt
    76921 tcaagggaaa caggttcttg cgcgattttc aagatttctc ggactttttc tgttggaaga
    76981 tccatttccg caccgatttc ttctggcgta ggttctcttc caaggtcttg cagcaattga
    77041 cgttggatac gtatcaattt attaattgtt tcaaccatat gaactggaat acggatcgta
    77101 cgtgcttggt cagcgattgc tcgagtgatg gcttgacgaa tccaccatgt agcataggtt
    77161 gaaaacttaa atcctttgcg gtagtcaaat ttttcaactg ccttcatcag tcccatgttt
    77221 ccttcttgga tcaagtcaag gaactgcatg cctcgtccta cataacgttt agcgatactt
    77281 actactaaac gaaggtttgc ttctgccaga cgctgtttcg cttcttggtc gccttcttcg
    77341 attttcaatg ctaacgctac ttcttcttcc gcagttaaaa gggagacacg gccaatttct
    77401 ttcagataca tacgaaccgg gtcattgatt tttacaccgg ttggcgcaga aagatcttct
    77461 gtttttgctt gttcagcttt tttctcagca ctcttcaagc tgtgaattga tggatcacca
    77521 ttttcatcca ccacactgat acctgcgtct tcaatctttt ggatcaattt gtccatttca
    77581 tctgcattca aagtgaatgg tgtagcaagc tgattggata aatcatcata tacaacttgt
    77641 cgtttgggtt tgttttcttt gatgaaagct gctactgctg cttcatacgt ttttttatct
    77701 gttccatttg ccataaaaga aggcccccct tgagtagcta tttggcttgt tttaactgtt
    77761 tcgttaaatt gatgatttca atcgtcaatt caagctcaag ctgtttgttt ccagttcgtc
    77821 tggcttcttg ctgcatttgt ttttttaatg ttatttcatc agctaagcca gatttgctga
    77881 tcacatctag caagtcttgg atttctcgtg gcgaactttc ttctgccacc ggtaaatatt
    77941 cgatttccac caccaaccgc cttaaatttt catcttgcaa aaagtctaaa aactctgcaa
    78001 ggttgaattc ataatgttgt gagacatatg catcgaataa aaaataaact tctgcatatg
    78061 catcatgaat aaactgaaat tctcgttctt ttaaaatatt acggacagaa acttctttaa
    78121 atgcacgata taatagaatc tgctctgcct tttctacttg cgtcaaaggt ctctttttcc
    78181 gtgcagtttc ttgtctcgta acctgagtgt gttgactttc ctgaggttct tgacgatttt
    78241 gctgatttgt ccttcgaaga tcgcgcagtt gtttttgtat cgtctctctg ccgatctgaa
    78301 actctgttga cagttgagat agatacatat cttgttcgat tggtgaaaca actcggctaa
    78361 gttcaactag taattcttcg aggtattcga tcttgtcttt ttcattatct aaatttttcc
    78421 cttgttttaa ataacgtgat ttaaaagtaa agactgtttc gcgcccatga gccactaatt
    78481 cttggaaaga tgcttctcca tacttacgga gatattcatc aggatcaagc ttttctggaa
    78541 cgactacgac agaaagtgct aatcgactgt tttgccgaag caattcaatc cctcgattgg
    78601 ttgcttcaaa acctgcgttg tctccgtcat agcaaaagac caattctttc gtcagctttt
    78661 ccatttgttg gatctgttga gctgttagac ttgtccccat agaagctaat ccagttttga
    78721 taccagcctg ccatgcagca atcacatcca taaacccttc gaacaacaaa atttctccgt
    78781 ttttccggat atcgcttctt gctttatcaa gattaaataa aacttgtctt ttattgaaca
    78841 gttctgtttc tggactattc aagtatttgg gctgatcttt ttcctgccct ttttcaggtg
    78901 caagccagcg tcctgaaaaa ccgatcgtct ggccttgaga attacgaagt ggaaacatca
    78961 ctctttgata aaaacgatca gacatacggc catcatcatg cgtgacaaac aatccagagc
    79021 gttctaacaa ttcatttgaa attgattcat tcttgaatac ttgctgaaga aaagaacgct
    79081 cattaggtgc aaaacctatg ttgaattctt caattaattc taaagacaac ccacgacttt
    79141 gcaaatattc taaagctggc tgtccagctt ttgtatgcaa tagcatgtga tgatagattt
    79201 ccgctgcttt ttcatgagca gcaatcagtt tccccgtagc agattcagga ttttggacag
    79261 ctatagtacg ctgacgccat tgatcttcta acggtatctg ttcgaagtct gccactttta
    79321 ccactgcttc tggaaaactt agaccttcta gttcttgaag aaaagtaaac acgtttccgc
    79381 ctttaccaca accaaagcaa tgaaaaatct gcttgtcttc tgcaacagaa aaagacggtg
    79441 tacgttcttc atgaaaagga cacagcccca agtaattttt accagacttt ttcaactgga
    79501 catattgtcc aatcacctca acgatattcg tttgactgcg tactgtttcg ataacctctt
    79561 gaggaatccg ttgagccatt ttttcacccc ctgctctatt gatatctttt gggtttaaca
    79621 gaagatattt caggagaata accggtaaaa aatcgcacta actgaaatca gtgcgatttt
    79681 aaaggacaca attatacatg tttgattgta tcatatttca ttgctttttc aagtataaca
    79741 catttctatc tcattaagca tcaatttgct actcttttca gtaactgatt ttgaatatca
    79801 gccttccagt acaatactcg aagaacaata tttacgagca tgaatacaaa gaagtatcct
    79861 acgctctctc ccaaccctaa gtttacttcc aaaattccat ggaacagcat tgcagctaca
    79921 tatatcccta cgatcgtcgt tactgctagg aagatgcgca atgggttgaa gggataacaa
    79981 gcttttacaa ctgccatgca actgatccca atcagcaagt aatacatcaa agtagtagtt
    80041 tcagcatttc cccatgcgaa tgtttttcca agtagataca ccgcaatgat attcactact
    80101 acaagcaagg catttggtaa agcattaata agtgctgtag gcaaataacg gtaagtgatt
    80161 tttcttttat cttgttcaaa agataaaaag aaggaaggat acccttcaat cgctaaatca
    80221 atcagcgtga tttggatagg gataaacgga aatccaattg ctgtaacggc acatataatc
    80281 gataaaataa atgaataaat cgttttgata aaaaagatgc ctgagacttt cgtcacattg
    80341 ttgaccactc ggcgtccttc aaacaggact tctggcaatg tagtaaaatc agagtccaac
    80401 aataccagat tcgcaatctg acgtgttgct ccatcacctt ctgccatagc aatgctgcaa
    80461 tctgcttctc ttaacgccaa aacatcattc acaccgtcgc ctgtcattgc aaccgttctg
    80521 ccgctttctt tcaattcatt taccagcaat ttcttttgct gcggactcac tcgtccaaaa
    80581 accgtatagc gatgagcagc ttctcgcact tccatttctt cagtaatttg agaaagatcg
    80641 acatacgcat cataattcgg taatcctgca cgtctagcga tattggagac agtaaaagga
    80701 ttgtctccag aaatcacttt cagatccaca ccttcctcat gaagataagc tagtgtttct
    80761 tgagcgtttt ttcggattgg atcatcgatt tcaaacagag caaccggctc aacaaatgct
    80821 ggtttttctt cgttcaattg ctgatttgga gcgatcccca acataagtac gcgatagcca
    80881 ttcgcttggg ctgtttttag actgtccgga agccgatctt cttccaccaa acgttcaggc
    80941 gctcctacgt acacgactcc cagttctgga aattccatcg cgccccattt gcgatcagaa
    81001 gaaaatgcga ctttgtttgt cacatcatac cgattagaaa gctcaaaata atctctcata
    81061 gcccgcatag tgatgttgtt atcactgctt tctgccagat acgtccccat aatttctggg
    81121 atggctttct cgtacagcgg atgtagtgct tctacccgct ggatactcat tttcccttca
    81181 gtaatggtcc ctgttttatc caagcataat gtatcgacat gggccagcgt ttcaattgaa
    81241 tacatgtctt gaacaaggat tcgttttttt gccagtttgg ttacccctgt cgttaatgca
    81301 atacttatta gcaataccaa accctttgga agcatgccta acaaagctgc tgcagatgca
    81361 ataacagaaa ttttgataga agcatcgcgg atgaacagtg cttccaaaaa tagtatgatc
    81421 cccaaaggaa taatcacgaa actagtgaat ttggatactt tgcgaatcga atctacaagt
    81481 tcagaacgaa tagctttgtg agtctttgcc tcgctagtca agcggacagc ataattatct
    81541 gcacctactc ggataacttc agccatgaca gaaccgcttg tcaaaaagct tccagaaagc
    81601 aattcagctc cagtttcttt gacaatcaaa tcagattcgc ctgtcaaaag agcttcattt
    81661 gcttctgccc gtccagatat aacctgtaaa tcggctggta tctgttctcc tgctccgatt
    81721 tttaccaaat ctcctaatac cagctcttta gtagaaatcg attgttcttt accgtcccgg
    81781 atcactagta cttctgattg ggaaacaatc gataatttcc gtacaagatt tcttgcatgt
    81841 atttcttgat aaattccaat aacgatattg acgacaataa ttgctaaata cgccatgttg
    81901 gaatacgcac ctacaaataa cagacaaatc ccaataccaa agttcagaaa attgaataac
    81961 gtcaatatat tatcgctgaa tatttgtttt gtactttttg atgcatcttc ctggtagtca
    82021 ttttgctggc cagaagccat tttctgaact acctcttgct gtgtaagtcc attcattttc
    82081 tttttctcca ttttccgcca actttcaaaa ataatcacgt gtttaagtct agcgtgttcc
    82141 aagattaaaa acaacttgtt tttataaaat ttatagaaaa acacacgaat gattttacaa
    82201 aaaagatgcc aacctttttg tttgaatcac ccgtgtgctg tttttattat caatctatct
    82261 ttacttatat tgttcctcca aacggctcat ccaccaacct agtgctgtac cggctataaa
    82321 aagaacagga caagctagta ccccagcaac tcccaatccc gcgtaatcgg taggaatgat
    82381 cataatcgtt gaagcaaaaa ctacacctaa aatgaaatgg aatagcttgc tatatgcctt
    82441 tgagaaaatg taatccatga tttttgacaa tccaagaaca caaagaatcc caccaattcc
    82501 gatcggcaca atcacttcaa gtcgtacttc tttaaatccg tcagccatcg ctttatacaa
    82561 tcccatatac accaaaaaat tagaagggct caatcctggg acgatcatac ccaaaccaat
    82621 caatccgccg gcaatcagcc atgttccaaa attctgatcg acttgcccgt caaataattg
    82681 agcgccgtat aataaaaaca aataagccag aacaaaagta acaaccatga tgatcacatc
    82741 agaagtatct cttccttttt tccctgcttc tttccataac gcaggaacag ttccagcgat
    82801 acatccgaca aaaaaccata atatcgttgt ttcatacgca cctaataaaa aactgactaa
    82861 aaaagaaagt agaaagatgc ctgtcactcc gcctagacca acaggcagaa aaaacaaaac
    82921 attttctttg aaattttttg taaggtgggc taaaaaagaa atcagccgct catacatgcc
    82981 aaagacagct gctaatgcac caccgctgac tcctggcaag ataaatcctg aaccgataaa
    83041 cattcccttc acaaaccgta acatccagtc tttggttgtg taccccactt cttgattttc
    83101 cattttttgc cttttttcca ctatttgcgt actccttctt tcatttaatt ttattcatga
    83161 ttgaacattt cctgctattt tacttaaaga ctttttcata ggtctctatt attttttcat
    83221 tcattttgac aatatcagga taaaacatgt tacctccatt atgatagaga tagccgccat
    83281 tgtaaagcaa ggactggatc cgccaatatc ggtattgttt cccttcctca tttcctaaaa
    83341 gtgggctcag cacatcttta gaatacgctt ctgctaattc tactgtgttt tctccgccat
    83401 gattttttac ataggcaata taatctttcc caaaattata tgcttggaca gctgtccata
    83461 aatcgcatcc ttgtttcttt gcttctacta tcatttccgc caaatatttg acaccttgat
    83521 caatactgtc agctggatta tcaatgatct cagcttctcc atgcagactt tccgagctct
    83581 gcatgagatc tgtccctttt ccttttgatt cggtcaatat tatcgccttg atcaaattct
    83641 cgtagttttc catatgataa ttttttgcag ctgttgttat ttctatttga tagctttcca
    83701 ctcgttttac cgaacgataa gttcttcctc ataaaaacaa caccgcacca ataaccgtca
    83761 gaatgatcat gtaaaaaaga atacggataa tagataatcg ttttcgcttc atttcatcac
    83821 ctagttattt tgacatcttt ttttatctta ctatttcttt atcttcttgg ctatttcttc
    83881 cttgatttct gtgtacgcct taagaaaaaa tgaattttcc tgtatttttt gacatcttac
    83941 gaaaatgatc gttgtttttc agtaaaaaca attgcccaat gactgatata atcgttatac
    84001 tttacacagt aggtgattat gtgaaaaaag aaaagaaata tgcaaaaatg ccagatggga
    84061 gcgaaattta ctatgaaaag agcggtcaag gcttccctct ctttttactg catggcaatg
    84121 acggcagcgg ccgctttttt tcagaacagg tccctgtact cgaacgctac tataccgtgt
    84181 atctagtaga tagccgagga catggtcgtt cgacaaacga agcatctatg ttgaattttc
    84241 agttaatggc cgaggatctg aatacgatca tgttgctgga aaaaatcgat caggcagatt
    84301 ttcttggatt tagtgatgga gcaaatctag cactggtatt tgccagcagc ttccctaaaa
    84361 aagttcatcg attgatttta aattctggaa acacgcttgt taaaggcgtt cgtttttctg
    84421 ccagagtcat cagtaatatt cattatgcat gggtatggtt actctcttta tttcgcccaa
    84481 gtcttcgcaa aaatctttta gttatcaaac ttttgctgca tgacatcggg cttacagaaa
    84541 atgatttaaa aaaaatcaac tcccccactt tgatcatcgt gggaaaaaaa gatgtaatca
    84601 agctaaaaca ttctttgtat atagctaaaa ctataccaaa agcttccttt gtgcttgtga
    84661 aagaacaagg acatgaatta gctagaaaag atcctgaacg cttcaatcga gaagttcttc
    84721 aatttctttc tgaaacataa ctattaggaa tagaaggtga tttatttgtt aaaaaatacc
    84781 atacaatggc tgaaaaacca cctaggactg ttcaaaacaa tctttttgat ttctgtcatt
    84841 gtcattattg tcggtgaatt gatgtccatc ggtaaaactc tatctatcca gcaattagga
    84901 gaaacgtttg ccactatacc tgtatggaaa agcggactaa tgctattgat tggtcttatc
    84961 tctgtgttac ctatggttgg ttatgatatt attttgaatc ggatgcttga acaaaagcag
    85021 aatcctcgtt acctgtttga gacaagctgg ctgatcaata cgatcaacaa tattgccggt
    85081 ttcggcgggt ttgttagtgt ggggcttcgc tctgaactat atggacaaaa gaaagagagc
    85141 agaaacgtga tccaagcatt atcgaaagtt ttcttgtttt tgatggctgg actttctatt
    85201 tacagtctgc tttctttttt acttgtagtc ttcacgccag ttgctccttt tttgaagcaa
    85261 tattggatat ggttgatcgg cggcggtcta tattttcctg tcgtcttttt atttactact
    85321 ttcaaaaaga aaggattcct tggtggtacc tcacttaaaa ctcaaggaca gctattgcta
    85381 gtttcattgt tggaatggac cggtgtcctg tttagtttcc tttctgttgg ttatttaatg
    85441 gaaatccgga ttgatctgtg gcaaacaatt ccattattca ttgctgcttc agtgatagga
    85501 atcgtgtcta tgattccagg agaaattggg agtttcgatg taatgatgat tatcgggttg
    85561 tccgctattg gtgtgccaag agaaatagtc gttgtgtgga tcttgctcta tcgcctgttc
    85621 tactacatca ttccgttttt gattggaatc gtctttttct tcaaaaatat cggttccact
    85681 tttgatcagc gttattctgg tatccctaaa caattagcaa cagaaattgc gcataaaatc
    85741 gtggttgtct tattatactt ttctggaatc atgctagtac tttctgccac tatcccgcaa
    85801 gcttttacag agtttcgctg gcttcatagt ttgaacccat tgaaatttca ttttattatc
    85861 caatttccta gtatactatt gggatttctt ttaatcatta tgggcagagg gatcgcagca
    85921 cgtgtgaaac gagcatattt gcctacaatc ttcttgattg ttctagcttt actttatgtt
    85981 ttattaagtg attttagttt cacaccggtg gttttcttgt ctattctgct tctgatcatt
    86041 cttgcttcta aaaacgaatt atttcgggaa caattgatct attcatggga gtggcgtacg
    86101 atcgatggaa tcattattgg tgcactgtcc ttgctttaca tcgttattgg ggtatacaat
    86161 ctgccggatt tccctcatcg gcgtcaccat tttatttcct ttttcttatt tccttctgaa
    86221 aagatttggt tttcgggatt gttggccatc atcgctgtta gtttcatgat cgttctattt
    86281 gttcatttcc ttcaaggaga aaagaaacag attggcgaag cctttaatga agaaaaggcc
    86341 ctgaagatcc ttacaactta tggaggaaac tccgatagtc aattgatctt cttaaaagat
    86401 aagcggatgt ttgcctatga aaaagacggt gaaccaactg ttcttctcca attcgcttgc
    86461 ttcaataata aatgtattgt aatgggtgat ccttctggta agaaagaaga ttttccagaa
    86521 gcaatcgaag cttttatcga agaaacagat cgactatgct atttaccagt tttctacgaa
    86581 acaagcgaag agattgttat gattttgcat gaattcggct acgatttcat taagatgggg
    86641 gaagaagctt atgtagacct gaatagtttt acaacttcag ggaaaaaaat gaagggcact
    86701 cgtgctgtct tgaatcggat cgaacgagaa ggatttacat ttgatgtctt acaaccacca
    86761 ttttctactg agcaaatgag tactttcaaa aatatctctg ataattggtt gggttcacga
    86821 aaggaaaaag ggttttcttt aggctttttc tctgaagatt atctacaaag agcgcctatt
    86881 gcagttgtca aaaataccca agaagaaatt gtcgcttttg caacgatcat gcctacttac
    86941 acgaacaata aagtaggaac gattgatctg atgcgatatg attctaaaaa agcaccttct
    87001 ggcagtatgg atttcttgtt cttgcatttg tttgcctata tgaaagaaga acatatccaa
    87061 tggttcaatt tagggatggc ccctctttca aatgtcggaa cttccagaaa gagtttttta
    87121 caggaaagga ttgcatactt ggtttacgag tttggttctc atttttattc tttccatgga
    87181 ttaagagaat ataaaagcaa gtacgctaca aactgggtct cacgttatac tctatattct
    87241 agagatagtt ggattgcata tgttatgatt gctttgctga ttattgataa tgcgccagtt
    87301 gagcagacac aaggtagaat aagtggtttg aaaaaatgga tacgaagaaa gtattaaaaa
    87361 ctgcataccg atagatgaac actctcatga tgaataaaag agactgaagt aaaacgaaag
    87421 ttcatgcttc tacaatctct tcttatacaa ttgaagaaca aagagcggtc caaacagaaa
    87481 tcctgtttgg accgctcttt tattttaaac atttttcatt accaaaatat tcgagtcgcg
    87541 tttcttatgc ttcgatctct gtaacgatac ctgaacctac tgtccgtccg ccttcacgaa
    87601 ttgagaatgt cgttccgttt tcaacagcga ttggatggat caagtcaaca tcaatcgtca
    87661 cgttgtcacc aggcatgacc atttctgtat cttctggcaa tgtgattgtt cctgtaacat
    87721 cagttgtgcg gaagtagaac tgtggacgat agttgttgaa gaatggagta tgacgtccac
    87781 cttcttcttt tgtcaacacg tacacttctg ctttgaattt tgtatgtgga gtaatggaac
    87841 ctggtttagc aagtacttgt ccacgttcga tatcgtcacg ttggatcccc cgtaacaaca
    87901 cgcctacgtt atccccagct tccccgtaat ctaacgtttt acggaacatt tctacacctg
    87961 ttacaactgc tttttgtgtt tcaggtttga tccctacgat ctctacctca tcaccgacac
    88021 gaacagcacc acgatcaata cgacctgagg caacagttcc tcgacctgta attgagaaga
    88081 cgtcttccac tggcaatagt aatggtttat ctgtatcacg ttctggtgtt gggatatatt
    88141 catctactgt atccatcaat tccataatag cagcttcagc atctggatcg ccttgcaatg
    88201 cttttaatgc ggaacctttg atcacaggag tgtcatcgcc tgggaaacca tattcgctca
    88261 ataactcgcg aacttccatt tctaccaaat cgatcaattc ttcatcatcg actaaatcaa
    88321 ctttgttcaa gaaaacaatc aggtatttta caccaacttg gcgtgacaat aaaatgtgtt
    88381 cacgtgtttg aggcatcgga ccgtcagttg cagaaacaac taagattgca ccatccattt
    88441 gtgctgcccc tgtaatcatg tttttcacat agtccgcgtg tcctggtgca tcaatatgcg
    88501 cgtagtggcg tttttctgtt tcatattcta cgtgtgcggt attgatcgta atcccacgtt
    88561 cacgttcttc tggagctgca tcaatactag catagtcttg aggatttgct aggccttttt
    88621 tgcctaatac tgtagtgatc gcagcagtta aagtagtttt cccatggtca acgtgtccaa
    88681 tcgtaccaat gttaacgtgt ggtttacttc tgtcataatg ttcttttgcc ataatttaca
    88741 aacctcctaa ataatataga tcactgaaaa atttcagctc tcaccttttt attatagtct
    88801 ttttttgact aaatcaaaaa gaatacgtcc gacttacttt ttgtaagatt cgaactaagc
    88861 ttattatacg tcaatattgg tcaaagtcaa ctaagagcac tcgtctgtct tatacgcgaa
    88921 aaaagtacct tttataaata aaaaaatgtg ttttttgaga aaaacttcaa gatagtcctt
    88981 aactttcttt tgaagcaata agaacaaaat gaggaaaagt ttaaaattca gctgttgcca
    89041 acaactttca atagacgaaa tcttctattt cgttaataat aaggaaagag gtgaagtaca
    89101 tgaaaaaatt aattggcgta cttgtcgttt taggcatatt tctcggcgga agttttgcag
    89161 cttatcatta tttttacggc ggcgaagctt attatacaaa aatcacgacg aatggcgaaa
    89221 tgtcagctac ccaagcagat aacggagaga aattcacgac ttatacctac aagcaagcgg
    89281 cttataataa agatggtgaa aaaaaacagg tgacgcttcg cgaagaaaga gaacatccat
    89341 taaagatgaa tgcgtatctt aaactcaaag tcaatcctcg taaaggtgta ttaagctggg
    89401 aagaaataaa ggcttctgaa gtgcctaaaa atgcggcaga aaaaatcgat aattagtaaa
    89461 tggtcttaaa attttattag ataaaaagag gctgggacag aagcgtttaa ctccaagaaa
    89521 taagaaggag ttgcttctgc ttccgccgtt tatacgtgtt tagagcgtga gacaaaagtg
    89581 ttctttactt ttgtctcacg ctcttttttt gttatattcg tcttttccga tccttctctt
    89641 gacacaattc atttaactga tcactggtac ttgaacacct aatattctag tcatttttat
    89701 aaacgattca atacttcatc cacatttttg atcatcacgg atatcgtacc atccggatta
    89761 ttcacaaatt caatcaaatc tgggttgcga tatacatcta ctggtacgat cagttcgatc
    89821 ccgtttgata gcttgaattt ttgttttcca aattttttct cagaaatttc ttgtacttct
    89881 tttacaggag gtgcttctgg gacaaatcct tgctcttgta cttcttcttt aaaagccatt
    89941 tttgccgtga tgttttcctt gaagactttt tccgcaatca tctcatgatc caaccgacct
    90001 ttttcttcta tcgtatcata gacagcttct ttcaaatcag ccatgatatc aaattcttct
    90061 gtctcaaatt tttttccaag atgcttggct actttttgga tcacttttac attttcttct
    90121 aaagaaggtg caggaacact ttcgatcact cttccagaaa aataaagctc ttttttgcca
    90181 gaaaactcat attttttttc aattaattcg taggtccaat cagtcaaatt cacagcgaat
    90241 gcttcatctg ctttttgtgt tttcgcccct agaattgctc gattcaaaat caagcggttg
    90301 tcgatccctg cttcgtctgc ttcaacaaag tgagtgtaag cctcacgata attgactttc
    90361 aataaagata agtacatcac tgtatctaat tcatacaaga caacaaatac atctgcacta
    90421 ggtgcttctt cactttcttg gtagatatcg aaccaccgct gaacgattgc ttcacttgct
    90481 tccacaaaat tttcttgagc gattttaagt gattcaacga tcatgctttc ttctgctagt
    90541 tgtccagttt ttgtttgagc agaagagatt ttttggatct tcttttgaag aaaatcacga
    90601 atatattctt ttgtcagatc cagctctttt tgtgaaaaga ctggagaacc agtttctctg
    90661 tcaataatat gcagaattgc tttttttaaa tagatatcca ttttctcatt cccttctgtc
    90721 ttagtttacg gaaaaaaaat caaaaatacc agaatcaaaa tcattttctt ttaaacaaaa
    90781 atttcaagag tagaaacaaa atggattctt tttttcgaaa aatgcgctac acttatagtt
    90841 gaacgaataa aaaaggagct gaaagtatga attcattaac aagcacttat cgtctatcaa
    90901 atggttacga aatcccggta gtaggattcg gcacatggca aacacctgat ggggatgtcg
    90961 ctgtttcctc tgttaaagaa gcgctggctg caggttatcg ccatatcgat actgcccaag
    91021 gatacaagaa tgaagaaagc gtcggccaag cgattaagga aagtggaatt cctagagaag
    91081 agatattctt gacaacaaaa ttatggaatg caaaccacag ctatgaactt gtgatgtctt
    91141 cttttgaaga atcattgaag aagctccaaa cagattattt agatctgttt ttgatccact
    91201 ggccaaaccc tgttgctttt cgtgataatt gggaacaagc aaatgcagat acatggcgag
    91261 catttgaaga actgtatgaa gcaggtaaaa tcaaagcaat cggtgtgagc aatttcttac
    91321 cccaccatct agatacacta gcaaaaacag caaaaattat gccgatggtc aatcaagttt
    91381 tccttgcacc aggcgaatta cagacaactg tagttgagta tgcaaaaaaa catgatatga
    91441 tcctcgaagc atatagtcca ttaggcactg gtaaaatctt cgatgtgcct gaaatgaaac
    91501 aaatcgctga agcacatgac aagacgattg cacaagttgc tttgcgttgg tcgctgcaac
    91561 acgaattcct tcctcttcct aagtcagtga caccaagcag aatcaaagaa aatactgaat
    91621 tatttgattt tgaattaaca gaagaagaaa tgaaacaaat cgatcagtta gatggtgtag
    91681 tcggcaaagc aaaagaccca gatactaccc aattttaagt cgaaaggtga ttttatggat
    91741 ccaatcgaac gcttgaattc tctctcggaa gaagttaccc agacttttca ttccgatttt
    91801 gtctttttga tcgatgcaga gaaaatccaa cattttcctg caagaaactg gacacatgat
    91861 caaatcatcg aagaactgaa aaaacggttc gatcattcgc taatggtcaa accctggcac
    91921 gaacatgaag tcatttattc acctgaacta cctgtttttg ccttgatacc gaaaaaatag
    91981 aaa
//
LOCUS       DAFLWQ010000003        90088 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.003, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000003 DAFLWQ010000000
VERSION     DAFLWQ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 90088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90088
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.003"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(248..2140)
                     /locus_tag="L1V16_000171"
     CDS             complement(248..2140)
                     /locus_tag="L1V16_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1274544.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2137..3864)
                     /locus_tag="L1V16_000172"
     CDS             complement(2137..3864)
                     /locus_tag="L1V16_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1274545.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3880..4530)
                     /locus_tag="L1V16_000173"
     CDS             complement(3880..4530)
                     /locus_tag="L1V16_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBN1274546.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4734..5030
                     /locus_tag="L1V16_000174"
     CDS             4734..5030
                     /locus_tag="L1V16_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBN1274547.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5202..5822
                     /locus_tag="L1V16_000175"
     CDS             5202..5822
                     /locus_tag="L1V16_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBN1274548.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(5914..7080)
                     /locus_tag="L1V16_000176"
     CDS             complement(5914..7080)
                     /locus_tag="L1V16_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1274549.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7092..7445)
                     /locus_tag="L1V16_000177"
     CDS             complement(7092..7445)
                     /locus_tag="L1V16_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBN1274550.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7573..8595
                     /locus_tag="L1V16_000178"
     CDS             7573..8595
                     /locus_tag="L1V16_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HBN1274551.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            8614..8775
                     /locus_tag="L1V16_000179"
     CDS             8614..8775
                     /locus_tag="L1V16_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274552.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(9034..9468)
                     /locus_tag="L1V16_000180"
     CDS             complement(9034..9468)
                     /locus_tag="L1V16_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274553.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9578..11437)
                     /locus_tag="L1V16_000181"
     CDS             complement(9578..11437)
                     /locus_tag="L1V16_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBN1274554.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11555..12715)
                     /locus_tag="L1V16_000182"
     CDS             complement(11555..12715)
                     /locus_tag="L1V16_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBN1274555.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(13022..13933)
                     /locus_tag="L1V16_000183"
                     /pseudo
     CDS             complement(13022..13933)
                     /locus_tag="L1V16_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
     gene            complement(14099..15292)
                     /locus_tag="L1V16_000184"
     CDS             complement(14099..15292)
                     /locus_tag="L1V16_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1274556.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            complement(15376..15576)
                     /locus_tag="L1V16_000185"
     CDS             complement(15376..15576)
                     /locus_tag="L1V16_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBN1274557.1"
                     /translation="MNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVIM
                     NGNRIQIKRKQFEKIIDTLDTI"
     gene            complement(16000..16233)
                     /locus_tag="L1V16_000186"
     CDS             complement(16000..16233)
                     /locus_tag="L1V16_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1274558.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            complement(16240..16671)
                     /locus_tag="L1V16_000187"
     CDS             complement(16240..16671)
                     /locus_tag="L1V16_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1274559.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
     gene            17020..17193
                     /locus_tag="L1V16_000188"
     CDS             17020..17193
                     /locus_tag="L1V16_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274560.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
     gene            complement(17259..17867)
                     /locus_tag="L1V16_000189"
     CDS             complement(17259..17867)
                     /locus_tag="L1V16_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HBN1274561.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(17873..18901)
                     /gene="vanB"
                     /locus_tag="L1V16_000190"
     CDS             complement(17873..18901)
                     /gene="vanB"
                     /locus_tag="L1V16_000190"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HBN1274562.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGTFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            complement(18894..19865)
                     /locus_tag="L1V16_000191"
     CDS             complement(18894..19865)
                     /locus_tag="L1V16_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HBN1274563.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVGHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            complement(19862..20689)
                     /gene="vanW"
                     /locus_tag="L1V16_000192"
     CDS             complement(19862..20689)
                     /gene="vanW"
                     /locus_tag="L1V16_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance accessory protein
                     VanW-B"
                     /protein_id="HBN1274564.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGEPFSFWWLVRHA
                     DKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGHEVKEFPEPN
                     SDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVSADKEPQALYKITNG
                     SIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPESVDIQEENQ"
     gene            complement(20707..21513)
                     /gene="vanY"
                     /locus_tag="L1V16_000193"
     CDS             complement(20707..21513)
                     /gene="vanY"
                     /locus_tag="L1V16_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-B/VanY-G family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HBN1274565.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGRR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            complement(21684..23027)
                     /gene="vanS"
                     /locus_tag="L1V16_000194"
     CDS             complement(21684..23027)
                     /gene="vanS"
                     /locus_tag="L1V16_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBN1274566.1"
                     /translation="MERKGIFIKVFSYTIIALLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPDFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQAQSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
     gene            complement(23030..23689)
                     /gene="vanR"
                     /locus_tag="L1V16_000195"
     CDS             complement(23030..23689)
                     /gene="vanR"
                     /locus_tag="L1V16_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HBN1274567.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            complement(24307..24474)
                     /locus_tag="L1V16_000196"
     CDS             complement(24307..24474)
                     /locus_tag="L1V16_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274568.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            complement(24632..24817)
                     /locus_tag="L1V16_000197"
     CDS             complement(24632..24817)
                     /locus_tag="L1V16_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBN1274569.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            24962..25333
                     /locus_tag="L1V16_000198"
     CDS             24962..25333
                     /locus_tag="L1V16_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1274570.1"
                     /translation="MANIEDCPGFETFGADVKAARQAKRVSRKAMAEKINIDWRYLAN
                     IENDGAIPSLPVVIQLIKACGLPVERYFNPEIMREESELRQRVSHKLKLCPEEYLPII
                     EGAIDSAILIEKPKKNETEDV"
     gene            25591..25920
                     /gene="mobC"
                     /locus_tag="L1V16_000199"
     CDS             25591..25920
                     /gene="mobC"
                     /locus_tag="L1V16_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBN1274571.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            25881..27209
                     /locus_tag="L1V16_000200"
     CDS             25881..27209
                     /locus_tag="L1V16_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBN1274572.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            27191..27577
                     /locus_tag="L1V16_000201"
     CDS             27191..27577
                     /locus_tag="L1V16_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HBN1274573.1"
                     /translation="MDARAMSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECI
                     CVQSISYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAA
                     CSKRMRRRKEAERQRKRYWKPTHLEL"
     gene            27760..27996
                     /locus_tag="L1V16_000202"
     CDS             27760..27996
                     /locus_tag="L1V16_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1274574.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(28296..28499)
                     /locus_tag="L1V16_000203"
     CDS             complement(28296..28499)
                     /locus_tag="L1V16_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HBN1274575.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMLVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(28503..29447)
                     /locus_tag="L1V16_000204"
     CDS             complement(28503..29447)
                     /locus_tag="L1V16_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274576.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            complement(29448..33368)
                     /locus_tag="L1V16_000205"
     CDS             complement(29448..33368)
                     /locus_tag="L1V16_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HBN1274577.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKID
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLTERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            complement(33517..35598)
                     /locus_tag="L1V16_000206"
     CDS             complement(33517..35598)
                     /locus_tag="L1V16_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBN1274578.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            complement(35595..36824)
                     /locus_tag="L1V16_000207"
     CDS             complement(35595..36824)
                     /locus_tag="L1V16_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HBN1274579.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            complement(36814..37065)
                     /locus_tag="L1V16_000208"
     CDS             complement(36814..37065)
                     /locus_tag="L1V16_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HBN1274580.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            complement(37088..39079)
                     /locus_tag="L1V16_000209"
     CDS             complement(37088..39079)
                     /locus_tag="L1V16_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBN1274581.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     DRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            complement(39111..41510)
                     /locus_tag="L1V16_000210"
     CDS             complement(39111..41510)
                     /locus_tag="L1V16_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBN1274582.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            complement(41440..41862)
                     /locus_tag="L1V16_000211"
     CDS             complement(41440..41862)
                     /locus_tag="L1V16_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBN1274583.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            complement(41876..42412)
                     /locus_tag="L1V16_000212"
     CDS             complement(41876..42412)
                     /locus_tag="L1V16_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HBN1274584.1"
                     /translation="MSTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVERL
                     ASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTRGN
                     AEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFARQK
                     TPGWDVWGNEVECDLILT"
     gene            complement(42449..43312)
                     /locus_tag="L1V16_000213"
     CDS             complement(42449..43312)
                     /locus_tag="L1V16_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274585.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            complement(43404..43619)
                     /locus_tag="L1V16_000214"
     CDS             complement(43404..43619)
                     /locus_tag="L1V16_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HBN1274586.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            complement(43696..45504)
                     /locus_tag="L1V16_000215"
     CDS             complement(43696..45504)
                     /locus_tag="L1V16_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBN1274587.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            complement(45501..45977)
                     /locus_tag="L1V16_000216"
     CDS             complement(45501..45977)
                     /locus_tag="L1V16_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HBN1274588.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            complement(46052..46264)
                     /locus_tag="L1V16_000217"
     CDS             complement(46052..46264)
                     /locus_tag="L1V16_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBN1274589.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            complement(46286..47251)
                     /locus_tag="L1V16_000218"
     CDS             complement(46286..47251)
                     /locus_tag="L1V16_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1274590.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKNLTLKAKGLLSQMLSLPEDWD
                     YTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDAKGKMADMVYTIYEQPVLENP
                     VLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLSKKEKIITDGQSTHSIPIPSP
                     TPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEYAYLIQDRSIDREQLDEIVDL
                     MLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRFVLDCLRENTTKVRNIKQYLR
                     AMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYSCGEGESL"
     gene            complement(47297..47485)
                     /locus_tag="L1V16_000219"
                     /pseudo
     CDS             complement(47297..47485)
                     /locus_tag="L1V16_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604486.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(47742..48263)
                     /locus_tag="L1V16_000220"
                     /pseudo
     CDS             complement(47742..48263)
                     /locus_tag="L1V16_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
     gene            complement(48279..48977)
                     /locus_tag="L1V16_000221"
     CDS             complement(48279..48977)
                     /locus_tag="L1V16_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBN1274591.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(48934..50595)
                     /locus_tag="L1V16_000222"
     CDS             complement(48934..50595)
                     /locus_tag="L1V16_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBN1274592.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            50813..52213
                     /locus_tag="L1V16_000223"
     CDS             50813..52213
                     /locus_tag="L1V16_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HBN1274593.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(52465..53544)
                     /locus_tag="L1V16_000224"
     CDS             complement(52465..53544)
                     /locus_tag="L1V16_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1274594.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(53630..54589)
                     /locus_tag="L1V16_000225"
     CDS             complement(53630..54589)
                     /locus_tag="L1V16_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBN1274595.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(54601..56112)
                     /locus_tag="L1V16_000226"
     CDS             complement(54601..56112)
                     /locus_tag="L1V16_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBN1274596.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(56134..56697)
                     /locus_tag="L1V16_000227"
     CDS             complement(56134..56697)
                     /locus_tag="L1V16_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBN1274597.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(56703..57566)
                     /locus_tag="L1V16_000228"
     CDS             complement(56703..57566)
                     /locus_tag="L1V16_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1274598.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(57580..58476)
                     /locus_tag="L1V16_000229"
     CDS             complement(57580..58476)
                     /locus_tag="L1V16_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1274599.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(58651..59940)
                     /locus_tag="L1V16_000230"
     CDS             complement(58651..59940)
                     /locus_tag="L1V16_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1274600.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(59912..61429)
                     /locus_tag="L1V16_000231"
     CDS             complement(59912..61429)
                     /locus_tag="L1V16_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBN1274601.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            61627..62517
                     /locus_tag="L1V16_000232"
     CDS             61627..62517
                     /locus_tag="L1V16_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HBN1274602.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(62590..63414)
                     /gene="nadE"
                     /locus_tag="L1V16_000233"
     CDS             complement(62590..63414)
                     /gene="nadE"
                     /locus_tag="L1V16_000233"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBN1274603.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(63426..64898)
                     /locus_tag="L1V16_000234"
     CDS             complement(63426..64898)
                     /locus_tag="L1V16_000234"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBN1274604.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(65535..65897)
                     /locus_tag="L1V16_000235"
     CDS             complement(65535..65897)
                     /locus_tag="L1V16_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBN1274605.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            66120..66872
                     /locus_tag="L1V16_000236"
     CDS             66120..66872
                     /locus_tag="L1V16_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1274606.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(67012..67935)
                     /locus_tag="L1V16_000237"
     CDS             complement(67012..67935)
                     /locus_tag="L1V16_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1274607.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(67950..68222)
                     /locus_tag="L1V16_000238"
     CDS             complement(67950..68222)
                     /locus_tag="L1V16_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274608.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
     gene            complement(68692..70317)
                     /gene="groL"
                     /locus_tag="L1V16_000239"
     CDS             complement(68692..70317)
                     /gene="groL"
                     /locus_tag="L1V16_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBN1274609.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(70368..70652)
                     /gene="groES"
                     /locus_tag="L1V16_000240"
     CDS             complement(70368..70652)
                     /gene="groES"
                     /locus_tag="L1V16_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBN1274610.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            70877..71539
                     /locus_tag="L1V16_000241"
     CDS             70877..71539
                     /locus_tag="L1V16_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBN1274611.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            complement(71615..72907)
                     /locus_tag="L1V16_000242"
     CDS             complement(71615..72907)
                     /locus_tag="L1V16_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1274612.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            73077..73706
                     /locus_tag="L1V16_000243"
     CDS             73077..73706
                     /locus_tag="L1V16_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBN1274613.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            complement(73809..74618)
                     /locus_tag="L1V16_000244"
     CDS             complement(73809..74618)
                     /locus_tag="L1V16_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBN1274614.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(74673..75542)
                     /locus_tag="L1V16_000245"
     CDS             complement(74673..75542)
                     /locus_tag="L1V16_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HBN1274615.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            complement(75543..76859)
                     /locus_tag="L1V16_000246"
     CDS             complement(75543..76859)
                     /locus_tag="L1V16_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274616.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            complement(76856..78691)
                     /gene="walK"
                     /locus_tag="L1V16_000247"
     CDS             complement(76856..78691)
                     /gene="walK"
                     /locus_tag="L1V16_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HBN1274617.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            complement(78696..79400)
                     /locus_tag="L1V16_000248"
     CDS             complement(78696..79400)
                     /locus_tag="L1V16_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1274618.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            complement(79590..80450)
                     /locus_tag="L1V16_000249"
     CDS             complement(79590..80450)
                     /locus_tag="L1V16_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBN1274619.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            complement(80437..81006)
                     /locus_tag="L1V16_000250"
     CDS             complement(80437..81006)
                     /locus_tag="L1V16_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBN1274620.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            81387..81459
                     /locus_tag="L1V16_000251"
     tRNA            81387..81459
                     /locus_tag="L1V16_000251"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:81420..81422,aa:Lys,seq:ctt)
     gene            complement(81955..82341)
                     /locus_tag="L1V16_000252"
     CDS             complement(81955..82341)
                     /locus_tag="L1V16_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBN1274621.1"
                     /translation="MNKRKTEFILILISGITGILCSLLALMGGMFLSSIDSTTLNTTE
                     LTSKDIDMLVNLSGNVVLFGGITLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPF
                     FLLTLLWVIPGVLGIIAGLMLLIRKS"
     gene            complement(82338..82859)
                     /locus_tag="L1V16_000253"
     CDS             complement(82338..82859)
                     /locus_tag="L1V16_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBN1274622.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            complement(82861..83895)
                     /gene="sppA"
                     /locus_tag="L1V16_000254"
     CDS             complement(82861..83895)
                     /gene="sppA"
                     /locus_tag="L1V16_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBN1274623.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            complement(83928..85343)
                     /locus_tag="L1V16_000255"
     CDS             complement(83928..85343)
                     /locus_tag="L1V16_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HBN1274624.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            complement(85312..87465)
                     /locus_tag="L1V16_000256"
     CDS             complement(85312..87465)
                     /locus_tag="L1V16_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HBN1274625.1"
                     /translation="MIKSFPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTD
                     LEGTSAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKT
                     KGNVLWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWK
                     QKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLFRVL
                     FEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDAL
                     ASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEM
                     AAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIK
                     HLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQV
                     ANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPS
                     HSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQES
                     FFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGG
                     QRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAK
                     ACDQILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
     gene            87723..87959
                     /locus_tag="L1V16_000257"
     CDS             87723..87959
                     /locus_tag="L1V16_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HBN1274626.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            87978..88193
                     /locus_tag="L1V16_000258"
     CDS             87978..88193
                     /locus_tag="L1V16_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HBN1274627.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
     gene            complement(88896..89648)
                     /locus_tag="L1V16_000259"
     CDS             complement(88896..89648)
                     /locus_tag="L1V16_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1274628.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(89663..>90088)
                     /locus_tag="L1V16_000260"
     CDS             complement(89663..>90088)
                     /locus_tag="L1V16_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBN1274629.1"
                     /translation="KNEYLKSLLIAKLYQANNNKICCKFECPSTIIEVPVPIFDCIRV
                     LGIILDNAIEASIESQDRELSLAIYRDDKQIEISISNSCREILLSIDTLMKKGITTKK
                     GHQGLGLSSIEEINKKNPNMFVNYQNDPYQFTTQVILLF"
BASE COUNT        23986 a        20768 c        18109 g        27225 t
ORIGIN      
        1 tatttttcgt ttggttgggc ttattaccgc agatgcaagc ttttgaacac cgtttaagga
       61 agaggttgta aaatcagcgg tttgacctga gtattagaga tacaaaacgg aaaaatagct
      121 tctcatattt tgccgttttt tgagctaata ccgaaggaca gctgattgaa caccgtttat
      181 tcggaaaaag ggactgtgac acgacttttg tcacagcccc taaaaaaaat aataaatttg
      241 tactattcta tgaagcttct tcttcagaaa actgactgtt ataaagatct gcatagaatc
      301 cgtctttttc catcaatgta tcgtggtttc ctgtttctac gatcgaacca tgattcatca
      361 caataatgtt gtctgcatcg cgtattgtag acaagcggtg agcaacaacg aaacttgtcc
      421 ggttttccaa taggcggttc atcgcttttt gaatcagtat ttctgttcgt gtatctacac
      481 tagatgttgc ttcatcaagg atcaggacat ctggatttgc taagaatgcc cgcgcaattg
      541 tgattagctg acgctgccct tgcgaaatat tgcttgcatc ctcgtttaat acagtgttat
      601 atccttctgg caatttacga acaaaatcgt ctacgtgagc agctttagca gcctcaatga
      661 tttgttcgtc tgttgcatcg tcgttcccat atttgatatt gtcatagata cttcctgtaa
      721 acagccaagt atcttgcagt accattgaaa actgtgcgcg caattcatca cgtgaaagat
      781 cacgggtatc tacaccatcg taacgaatac tacctccaga aacatcgtag aaccgttcaa
      841 gaaggttgat cagtgtcgtc ttccctgcac cagtcggacc tacaatagcg accatctcac
      901 caggtttgac atccaagtta aaatcagtca ttagcaagtt atctggtgtg tagccgaatt
      961 gaacattttc aaaacgaact ttgtatggtg tatctttttc ttctggaagg ccagattttt
     1021 cattggacat ctcttcttca tccaacactt caaatacccg ttcggctgaa gcaactgttg
     1081 attggatagt gttcatcaaa cttgcaagtt gagtgattgg ttgagagaac tgtgttgtat
     1141 attgcaagaa cgcttgaaca tcccctaatg tcatgttccc atttgcaact tttactccgc
     1201 ctagtacagc gacgaacaca tagcctagat ttttaacgaa attcatcaac ggcatgatga
     1261 ttgccgaaat aaattgagct ttccaaccag cggcatacag attctgattt tctttttcaa
     1321 atacttcctg gtctttttca gtatgattga atgttttaac aatggtatga ccaccatatg
     1381 tttcttctac ttggttattc aataaaccta aacttttttg ctgatctgcg aaaaacactt
     1441 gtgatttcgg cgctacgatc atcacgatga tcaagcttaa agggatcatc aataacgcga
     1501 ctaacgtcaa ttgccagctg attgaaagca tcatcacgat gaccccaatc aatgtgactg
     1561 cactagttac aaattgagtc aaattttgct gcagcgtgct tgcgatgtta tccatatcat
     1621 tgattgctcg agacatgata tccccatttg tatgtgtatc ataataggaa atcggtacac
     1681 gattcatttt ggcttccaaa tcatgacgta attcataaac tgttcgttgg gaaacacgtg
     1741 tcataataaa ttgctgtaaa aagttgaata cagcagaaat caaatacatc acgattactg
     1801 tcgcaatgat ctgcgcgatt ttatcaaagt ctatcggaaa ttttgttact tgttggcctt
     1861 gttgcatctg ttgagcgcca gccattacac ctttgaatat ttctgtggtt gctttcccca
     1921 agacctttgg tgtttggatt tggaagatca cggctgctat tgctagtaca aatacagcga
     1981 tgatcgcaac catacgttta gacatatagc caaacaatcg gcgtaccgtt ccccagaaat
     2041 ttttaggctt ttcacctttt acaccgagat ttctgccagg tccaccatgt cctggaccgc
     2101 ctgctggtcc atgagaggga cgtgtgtttg ttttactcat gctaagtcct cctctcttag
     2161 ttgtgaatga acgatttctt gataagtttc gtttgttgct aatagttctt catgtgttcc
     2221 tttgccaacc agttttcctt catctagcac aaggatcata tctgcatcca ttactgtact
     2281 tactcgttga gcaactaaaa cggtgatact ttctttcata ttcgttttca atgcttggcg
     2341 aagattggca tccgttttga aatccaacgc tgagaaggaa tcatcaaaca catagatatc
     2401 tgctgttttg actaatgccc gtgcaattgc cagacgctgt ctttgtccac cagagaagtt
     2461 tcctcctcct tgttccacat ggctatctaa gccatcttcc atctctgaaa caaaatcttt
     2521 agcttgtgcg atttctaatg ctttccaaat catttcatct gttgcatccg gcttaccata
     2581 ctgcatattg tctcggatcg ttccagagaa cagaactgct ttttgaggaa caaagcccat
     2641 taattctcgc aaattatatt gagtcatgtc actaatgtcc gttccattta tttggatcga
     2701 accagattcg atgtcatata atcgagggat caaattgact aaggtcgttt tacctgaacc
     2761 agtcccccct atgattgcga cgatctcgcc cgacttggct tggaaatcaa tatcttccaa
     2821 tgcaagtttt tctgctccat gatatcgata attgacatga ttgaaggcca atgttgcgtt
     2881 ttttccagca aaagaaactg ttttaggatt ttcagggtca tggataccga ttttttcatc
     2941 caacacttca ttaatacggt cagctgaagc ttgtgcacga ggcaccatga taaaaatagc
     3001 ggaaagcatc ataaagctga tcaagatctg catcgcataa gtcataaatg caatcagatt
     3061 accgacttcc aaagtcatat ctgctatgta gtgtccacca aaccaagtga ttgctacgtt
     3121 tgtaccgctc atgatcaatg tcatcattgg catcatcaat gcgacgatcg tattaacttt
     3181 gattgccgta tttgtataat ctttattcgc taaatcaaaa cgattttctt caaagcgtgt
     3241 cttatcgaat gctcgaatca ctctgacccc tgtcaatcct tctcgaaata ccaggtttaa
     3301 acggtcagtt ttcttttgca tacttttgaa taatggaaca gcaaagtaca tgattccgcc
     3361 gatcaaaata atcattactg ggatgacaac taagaagatt tttgtcaact gatgatcttt
     3421 ttgataagca agtatgctcg cgccaatcaa cgtgattggt gcattgatca tcatacgtaa
     3481 aaacatttgt gtaaccattt ggatttgagt cacatcattg gtcgttcttg tgatcaaaga
     3541 ggccgttcca tatttatcaa acgcatcttt tgtcagactc tctgattttt tatagacatc
     3601 cgtacgcaat tgcttaccca gtttctgtga ttcacgagta gcaaaaaatg tatttgcgat
     3661 agcagctaag atactgatca aagaaaagcc gatcatcaca aaacctgtat gccaaatata
     3721 atcgacatct ccttgcgcta cccctttatc aataatattg gaggtaagtg tcggcaaata
     3781 taaatctgcc agtacttgga tcaccatgaa aactgcagct gcaattgctg aagtcaagga
     3841 gatccgtttt acgattttta gcatctagtt cccttctttc tatttatata ctccgttttt
     3901 cagccaagaa agtttcaaat tgaattcact gattgcttgc tctactgagt aatcttcaga
     3961 tgttgaaaat aagcgatacg aatgcgcaat tgttgtaaat acagtattca tcactaattg
     4021 gatcagtaat tccaattcat gatcattttt tactttcagc ttcgtccgat cgatcaattc
     4081 aagcaactct tttgcatctt gtttgtgttc tttatgtgga tcgtgaggcg ttttttggcg
     4141 actcgtatga ggagcgactt ttcttgaggc acggtaatcc atgttcataa acaagttacg
     4201 ataaaaagaa gcattctcgc cttccaaaat ctcataaatc attttagaaa aataggattc
     4261 gaatcctttg aatagatcac catcggattc tttcattagt tgtaacatat ctttagagct
     4321 gtcacgtctc attgtctcaa agtaataaaa ataaagatcc tctttatctt caaaatactg
     4381 atagaaactg cctctaggga tatccgctaa tttgacgata ttagcaatcg aagcttcttt
     4441 taagggtact ctagaaaact cgattctcgc agcctcgatt agtctttttt gtttttcttt
     4501 aggcaaatgg aaaaatgtct gtgtcggcat atggatcctc ctttctttca agatgacaca
     4561 ttgtcatatg acgctgtgtc attataacac ctcctacctg ttttgcaaga catttgcata
     4621 gtttttttca ttatcatccg atacattaaa aaagtgataa gaggaatcct tccatttgaa
     4681 ttaatgagag ttgcccatta aaatagccac atactaaaca aaggatgaga taaatggccc
     4741 aatcaattag tgtccaagac ttcaataaat tgcctctcga tgctgacagc atcgttttag
     4801 atacaagaaa taccttagat tacacaaaaa accacttaag ccactcgctt tctatccccg
     4861 ctgctatctt gccaagacaa ttaaaaaatc tagatccaaa gaaactttat tatattctaa
     4921 gctatacagg caggcgatca gaagcattag ccgatcaact tactgctaat ggttttcgtg
     4981 ctgtttatat cattggtggg atggaagctc ttcagtcgag tgttgcttga atattgcttg
     5041 ttagattcaa aagaggctgt gacaaaaaat cgtgtcacag cctcttttat accctgtctt
     5101 tttttagtta tttattcttc aaccttatca atatgacttg atagcctttt ctttttctca
     5161 tagttataac aatcatagca ataaaaggag aaggtaagca tatggcatct gttttagtag
     5221 tcaaaggtca tcccctaact gcagaagaat cgcgcacagt taaggcattg acgtcttttt
     5281 taacaagtta taaagaaaat catccagatg atgaagtgac tgttttggaa ctttatcgcg
     5341 atgatattcc ggaaatcgat gaagaattat tatcaggttg ggaagcatta cgtgctggtg
     5401 cagaattcac ttccttatca gaaagtcaac aacaaaaaat tgctcgtttc aatgaattga
     5461 ctgatcagtt ccttgctgct gataaaatcg ttatcgcaaa cgccttatgg aatctaaata
     5521 tcccaacaaa attaaaagct tggttcgata ccgtcaatgt agctggaaaa acgttccgct
     5581 atacagaaaa cgggccagaa ggattagtga caggtaaaaa agcactgcac atccaatcta
     5641 atggcggtgt atacaacgga caagactttg cctctcaata tgtaaaaggt attttaaact
     5701 ttgtaggcat cgatcaagta gatcagctat tcatcgaagg aatcgattat gaccctgacc
     5761 gtgcagatga gttgatgcaa aatgcattag ataaagctgc tgctttaggt aaatcatttt
     5821 aaaaattgag ataaatgcat acaaaagaga cagaggaaaa aatcttcaaa gcagcatttg
     5881 taccttggat attttcccat ctgtctcttt ttgttattct ttctgctttt tcaacggatt
     5941 ttcttcataa agagaagaga ttgttgtgta ccattcaaaa acatgagtaa tcactacttt
     6001 agctgctgca taaacaggaa tccccaagat cacaccgatg attccgaaca atttcccaga
     6061 agtcagcaga actaataaaa tcgttactgg atggattgct aactgattcc ctagtactaa
     6121 tggagagatc aagcgtcctt ctattgtctg ctctactgca aaaacgatca gtactttgat
     6181 gatcatgaat ggacctgcta caatggctaa aaagatagcc ggaatcatcg ctaaaaatga
     6241 tcctaagtaa gggatcaggt tcaaaaaacc cgcaataatc cccaacgtga cagcatactc
     6301 taaaccaatg accgcaaaac caatcataaa catgattgcc acagcaaaag ccacagttag
     6361 ttgtcctctt atataagaag aaacttgact attcatttca ctcagcacat tcaacgtcgg
     6421 tttttgcatg cgtgtcggta aaaatttgac aaaataaggt gctaattgtt taccgtcttt
     6481 caatagataa aataagataa acggcatcgt cagcagagcc actaaaatag tcgctaccgc
     6541 gccgacaaaa cttccaagac tctgaactgt actcttagat atatcttgga tcatatcgcc
     6601 tgccgaattc atgaacttat cacctgctgt ttccaactgt tcgcgaaatt ggttgaacag
     6661 cgggtcccgc aaaatctcgg ttaatttatt atcaatcgta tctacatatt gagggaagtt
     6721 actgatgaag ctcactgttt gttcctgaat cttagggatg atcactacgc tcccccatgc
     6781 gattagtgca acaaccaaaa caaacagccc aatgatactg taaagccttg gtacttttcg
     6841 cttttcaaag taatcaacta ccggattcat caagtaatac aagattcctg ctaaaatgat
     6901 aggcagacct acgattgcta aaaattgcca gattggtgca aacaaatatg aaacttttgt
     6961 aaataaaaag acgatcagca atattaacaa tacaacaagt aaggctgtga ctacttgatt
     7021 atttaaaaac cagcgccaaa accacgatac cggtctgttc ttcttatttt ttccttccat
     7081 aattcctcct gttagttata aaaaatttgg cttcccaaac caatagcagg cagtctatgc
     7141 ggatgaagat agattccatt tgcaatttgt ccttcttctg gacaagcatc aaaaatcaat
     7201 gatacgtgag ctactgtctc taaattccca ttggccatcg gaccgacata atcgatcgta
     7261 tatacctgat catcaaaagc aattgttccg cctgctttca aagaaaaagg ttcgtctttt
     7321 gatacttctt gaatcaccga atattttcgt aaggcagctg ttgctgtttt atcgaacaaa
     7381 atcagcatgg gttcttcctt gtttattgct tctgtcccaa tttctgtaat ctttgcctga
     7441 atcattgcac tctctccttt aattgctttc aaaaacagta taacacattc tcattcttta
     7501 gccgtgtgga ataattatgt gatagaataa aaacgaaaac tatttcatta caattaggag
     7561 gaatcagctc atatgatcga aaagataatt ttaggaacct atacgcgtcg cgaaagtaaa
     7621 ggaatctata cgatcgacct tgatacagaa aaagaagaat tagccaacct ttcattagct
     7681 gttgaagaaa atagccctac ctatgtagca aaaagtaaag ctggcaatct ttacacagtt
     7741 actagtgtgg atggattagg tggtgccggt gcgtacgata aggattttca ttttttgaat
     7801 gcggtaacag agtctggcgc tcctttgtgt tatgtagcgg ttgatgaagc acgtcaatta
     7861 ctatacgggg cgaactatca taaaggtgaa gtaaatgtct accatatatt aggagatggc
     7921 gaactgaaag cagcagattc aatattccat caagaagcga caggtcctca taaaaaccaa
     7981 gatcatgcgc atgtccacta tacggatctg actcctgacc aacgattagt cgtatgtgat
     8041 cttggtacag atcgtgtgta tacttatgat gtgtccgaaa acggcaaatt gaatcttgta
     8101 actaccttca ctgcagagcc aggaacaggc cctcgccatc ttgtctttca tccaaatgga
     8161 caattcgctt atttatttgg tgaattagac agcacagtcc gcgtgctttc ttataataaa
     8221 gaaacaggtg cttttgaaga attacagaaa atatcgacct tgccagaaga attcgacggt
     8281 gaaaatggag gggcagctat ccgcatttca aatgatggca agttccttta tgcttctaac
     8341 cgaggacata actcgattgc tgtattcgca gtttttgaag atggttccca cattcaaaac
     8401 aagcaaatca tctcaacaga aggggatttt ccccgcgatt tcgcactaga tccaagcaat
     8461 aattttgtcg tgtgtgccaa tcagaacacc gataatctga cattatatcg ccgtcatcct
     8521 gaaacaggat tactggaatt actgaaaaaa gatgtctatg taccagaatg tgtctgtgtt
     8581 tattttgatc gttagtaaga aaaggagaat gaaatgaatc agcaagacgt attagacaga
     8641 ctacgggaag aactaaatat tcctttcttt gatgggaaaa tcgaagataa agagtatagc
     8701 gaagaggaat atcagaaact caaagccgat ttacagaact actttgaaca atatgtacag
     8761 aatgtagaaa actaatcagc tttccatact atctgaaaag aacatcagga caagactttt
     8821 ccgtctatcc tgatgttctt ttctacaaat aaaaaaccgc cgagatggtt agactcgacg
     8881 gaaaaggagt atttactcga ttttgagtaa gtacaaggtt gttgttggtt ataggtatgt
     8941 cattatcata aaggattttg atcactctat cataaaggta atattacatt tatattagat
     9001 aactctagtt tttattgtta tcaaagattt cttttatttt ttcaacaaca aattagtcat
     9061 tttttggatg gcagctgtca attggtctgt cgcttggtct tgttttgctt cagatgtatt
     9121 gaatagatct tcatctaccc ctgattcaag atcgatactt tggatcattt cttcacagcc
     9181 tgctacatat gaaagataag ctttttcaaa atttttatga atgcccattg cttttgctgg
     9241 tggacgcaaa gtactgactt tcttaagcat tgcccgatat ttttttgttc cttcttcaaa
     9301 taacaggatg atctcttcaa gagtcgattt gtccagttca cttgtttttc cttcatcaat
     9361 tgcgtttctg atcacttcat atttcggatg cattccttct ccgattgctt ctgtttcctt
     9421 gacgatttga tcgatggact gcacataata gccaatattc ggtaacatgt tcgttttcct
     9481 actttctcca ttgttgttat tatttattct acttgttttt atcctcaaat gacaagtact
     9541 tgaaaaaatt taatggtttc tatacagctc gccattctta ttcgtgctca aagaaaccat
     9601 ctgctaaact atattgtttc cctgcgacaa tgtcatattg gatcaattga tattcgtcgt
     9661 aaatctcttg ttgcgagcga ttgaattgcg cttctttata ccactgtccg ttttgatagt
     9721 acagttctcg ttcaaacgcc ggaagttcct gttctaatga taaaagcagc tgataaaagc
     9781 catttgttgt ctgattcgtc tgttccatta gattcgctgc aaaataaaac ggactggtga
     9841 ttgcatcgtg agtcgtttgc ttttctaatt ctcctttact gtcgaacata agaaattgtg
     9901 tttcatgcaa tgtttgtttg tcattttttg cttggatcgt atctgaatag atccctggaa
     9961 gatgatcccc ccaaaaaaca actaaagtcc ttctagaaag attcttcaat tcttccgtga
    10021 actgcttcag tgccgtgctg ctataggaaa tatcttgcag ataattctct aagtcaagtg
    10081 tcccacttcc atctgaagtt tttgcaggat agtctagatt atcatacttt ccatcgtagg
    10141 gcatatgtgt ctgcatcgtg actaaatgaa tgaactgagg tgttttttct tccttgagaa
    10201 gtgtcattac ttctttgtaa gctgactcat cagaaatata tggattattc tctatcgtat
    10261 ccgtataggt catcgtacgc tcgctgatga actggtcaaa tcctaatgtc tgataaacat
    10321 cctctctttt atacatcgaa gtattgtatg gatggatcgc tgtcgtctgg tatgattgtg
    10381 cgtttaacgc tgaaacgata gaaggaagct gatccatttt tggtacaagc atcgtgtaag
    10441 gggtggtgag ttgcgcatta aataacgcca tagaaaaacc agtcaatgct tcaaattcga
    10501 tatttgctgt tccaccgcca tagttttgag aaagcatatt gccactatat gtttgatcag
    10561 ctacttcata ataatctgcc aatggctcac cagatacttc tacgccgttt aatcgactag
    10621 gatctgagaa actttcactc atcacgaaca cgatgttcgg cgactcttcc tctacagttt
    10681 tatttttttc atcggctagc ttctggtatt tttcagtgat ttctttgatc ttttctttcg
    10741 aatatccttc aggttcatcc attggttcta ccttcagatt gtacaaaaac ccaccgataa
    10801 aaccagtgtt atagtagttc attttctggc tgtaaggtat ccatagtgcc gttttattat
    10861 atgcttttcg caacaaatta tcgggattgt tgaaattact gatataccct agcagtccaa
    10921 ttgccacaag cagtgtcgtt aatcggatca attggaatcg ccttcctttt ttcaggcttc
    10981 gaaacatgta ccagcaaaac aatcctatca cggttcctgc ggcagctaag atcactgtaa
    11041 acagcatagt gccggtcata tctttcagca atccgatttc agtgatcatc ttcaaatcgt
    11101 ctggataaat cggttcttgc cgataactca ttttcatata atttgcaaaa cctaatacac
    11161 cgatggctac gacatacgta agggaaccta aagggacaga tcctgctagt gcaatcagaa
    11221 aaataagaat aatcagcaag acgagacagg ctaagaagaa tttttccgta tgccaagaaa
    11281 aagcaaattt caacgcaagg tctacggata gatcattttg acaccactgc aaaaataaat
    11341 tactaaaaac aacaagaaaa aagatactga tgattgctgc tgttcctttt aaaatctttt
    11401 tctgtttggt cgaaagtctg cttatatatc ttttcaaatg cttgctcctt catttctatc
    11461 aataaaagaa tgttgcttct cttattttag ttgtacgaaa ttcgaaagta aagaacggaa
    11521 agaagaatta atgaaatcca aatattctct ttctttatgg cctttctggt ttctttaata
    11581 agcggacctt tcgtactcca gaaatttttt ctagctgttg tttcacttga ttgagctgtt
    11641 caaaatcagt actgtctatg tcaatcaata tgtagacatg ctcattctta tggttacgcg
    11701 atatatctgc gatcgctagc tcgttctcat tcagcagaga aaatatctct gctaatatat
    11761 tggttttctt ttgataaaat atagtgaatc gaaacggcgc ttggaaaaac attcgtgcgg
    11821 atggataatt gaccgcttct ctaaccgtac cgaacaaaag ataatctttt aaggcttcaa
    11881 ctgccaaacg tccgctgtct gccaaagctt cctgagtcga tccccctaga tgaggcaaca
    11941 taagtatacg gtcattttct aagaactctt cttctggaaa atcagtcaag tatttagcca
    12001 gatgttgttt ttccaatgct tgcataacag catatttatc aacaatttca cttcttccta
    12061 cattgataag tacagcatct tttttcattt tttctatatt cgcctgatcg atcaatcctt
    12121 ttgtatcttc tgtcaacggc agcatgacta cgatgtaatc cgaggtagaa agaactgttt
    12181 ctaaatctgc ttgccgaaca taatccaact gggcatcgcg gatagaataa cccaagacat
    12241 ccatccctaa gctatagcaa cttagcgcta cttttgtgcc tatcgctcca agaccaagaa
    12301 gaccgatggt tttgccttgc aattctcgtc ccacataagc acttcttttg ttttctgcct
    12361 gttctaaaat attaggacct gttagtgttt gtaccatacg acttgcttcg attatcggac
    12421 gggaagataa gagcaaacag cacaaaacaa gctcttttac tgcattagca tttacacctg
    12481 gtgtattcat gacgatcgtc ccgttttcag aagctttttc aacgttgatc gtgttcaccc
    12541 caacaccagc tcttgaaatt gctagcaaat ctggtgtaag ccattcatct ttcactttcg
    12601 tactacgaat aactattcct tcggctggca aatcatctat tattttgaaa tattcccctt
    12661 gtaacttttc tatctcttgt tctggaatag catcaatcaa atgaacgtga tacataaaac
    12721 cccctcctta ctaacaagta tctcgaaatt tctgcaatta gacaactgtt taccatttga
    12781 cttcctagaa gcaaaaagag cagttagagc agagtaggct gagtgataaa aataaggcta
    12841 tgacaagtta ctgccataag ccttattttc gagagcaaaa tattgagggt gagatatctt
    12901 gataaatggt gttccgttag ctgacattga taataagact aaatttcaaa aaagttgaaa
    12961 agcaaatttc gtcaatctct tcttatttct taaaactaag tggctttttc acaacctctt
    13021 tttatctaat aaccactgtt tccaactcaa ctaattttgc ccacgtttca atttgatctg
    13081 ttgttagatt tagcgagaca acggtatgat gaccgccacc tgcctgaatc catgaatgga
    13141 caccttcatg gaaattcggt ttagttttcc ataacacacg tgcaacaggt aaattaggtg
    13201 cttcagtcgt tggttcaaag gcttctactt cattgatcag cagtttataa tgcgtaccga
    13261 aatctgccat cgatacgact accccttctc ctgctttccc atcaaataca agacgcgccg
    13321 gatcttctct atctcccatt gataaaggag aaacaacgat tcttggtttc gtcgcagcaa
    13381 gcgtcggatc tacttccatc atatgggatt ccaagattgc ttcttggcca ctagctagct
    13441 cgtaagtata atcttccatg aatcctgtat ctttccctcg agccatgatt ttcagcaacc
    13501 gatcaatcgc tgcagttttc cagtcgcctt ccccagcaaa accgtatcct tctgccatca
    13561 aacgttgtac agctagtcca ggtagttgtt tcattccata caggtcttca aaattagtcg
    13621 taaaagcgtt atagcctcct tcttctaaga aacggcgaat accgatttcc tgctgagctt
    13681 gtacttttac atgttcctcc catgtctttt cttcataatc accatagtcg aaggtataca
    13741 attccttgta ctcttcaaat aattgatcga cttcttcgtc tgatacgcga tcgattactt
    13801 gtacaagatc tccgatacca aaataatcaa cagtccaacc aaattgaatc tgtgcttcca
    13861 ctttgtctcc ttctgtgaca cccacgtttc tcatgttgtc accaaaacga gccactttta
    13921 ttccaaaatt atatgggatt ttagattatc tttttagaag ttcttgaatg tcggtatagc
    13981 ccgtgtttcc gggcttttcc ggcatttttg atattgttag atacttacaa atgttcttat
    14041 tacctctcac catttccccc tcaaaagtag taaatggagt agtaaaaccg gccttgtgtc
    14101 aggctgccag ccgttccatt tctgcccttg cggaatcgaa tgtggcgtgt gcataatagt
    14161 tcagcgtcat ggtgatattg gaatgtccca taatgtactg caaggctttg gggttcattc
    14221 ccgcattggc taaccgggtg cagaatgtat gacgcatagc atggggcgtc gtcgttttcg
    14281 gcaacgcttc ttcatggctc ttgttgtact tcttcacaag cctgccaaac atcccgccat
    14341 aatctaccgc cgtcatggga tagccgttct gtttgagaaa caggaaattg gcatacccgt
    14401 caataatgaa cggctttgca cctttgcggt tttttatcac tcgctggaac gcctgataca
    14461 cttcctcatt catggggatt tttctgacgc cgctttgggt cttgggttcg tcaatatagt
    14521 aaccgacgcc ggtatttctc aaaagctggt ggctcacgat gattacccgg ttttcaaaat
    14581 ccaaatcttt gtccgtcagt ccgcacagtt ccgaaatgcg aagccctgtc cccagcagaa
    14641 taacgattgc gtcataatgc ttttggtaaa ccttatcacc ttgaataaag gacagaaaac
    14701 tttcttcctg tgctggtgta agaggcacct ttggttccgt atcgtcgtcc agaacgtcac
    14761 taagctggaa gtcaaacggg ttttttcgga tgcaatcgtc ctgtatggcg gtgtaaaaag
    14821 ccgctttcag ggaacgcttg tcgttattga tggtcttata agaaaggccc ttttctttca
    14881 tccgaagcgc ccattccttt gcgtcggaca gcttcacact gtcaatcggg cagctcccca
    14941 gccgatcttg ttccagaata cgcatcagcc gttcccggcc cagtttggtg ttgtgcttca
    15001 cattgccccg gtgcctgatc tgcttggcgt agagctggca gacggtcatt ttcttgccga
    15061 tggtgtctat cccgtcgtca aggtctttct ggatttcttt ctccttttcc cggagtgaaa
    15121 tatcctcccg tttacctgcc ggggtcttat ccgtaggcac taacttccat gagtaaacaa
    15181 actgcggttt tccaaaggta tcaacatatt tgtaagcata tcgtccgtct tttctctggc
    15241 tctctccaga ccgcaaaacg cgatttttgc tgtctcgtct tttttctgac atctcgtcat
    15301 gctcctttcc atgacggaaa gagccgcata tatgcttata aattattata acatatctgc
    15361 ggcccttttt cactattaga ttgtgtccaa agtgtcaatt attttctcaa actgcttgcg
    15421 tttgatctgg atgcggttgc cattcataat gacccagcca gaggccggat tttcctcggc
    15481 cagcttacgc aatttgtttt ctccgatacg gaaatattta gacgcttcct caatcgtcag
    15541 cgtgtatttt tcccaaatag gcacatcatg gttcataatg cagccccctt tcacaaattc
    15601 aaaggtttgt gtgatttagg ggcatagacg gacggctgct ggcacagctc cacgggactt
    15661 tcacccccgc gtggttctca cgcggcccta cccattgcct gcgacgcttt taacgctcgg
    15721 actgtggcta taagggagta tcatagtcct gcctgtacgt cgtcgcccgc aagccgccac
    15781 gctcacattg cggcgtggtg ttcctcgctc cgcttttccc gtagggaaaa gtatcatggc
    15841 gcaccagccg tccggctcgg cacagacaga atgtgtccgt atgccctatg atgcgccgcc
    15901 gttatcttgc gggcatattt atcaaggtgc gatcaggcca ccgggaaaac accgaaacgg
    15961 ggaaagggta agccgtttca tgctgccggg gccggttcgt cagttcgtga cgatagcgtg
    16021 gatgagcttg atttccagac ggcgcttcat ggcctcgtcc agacacacat gcggatagcc
    16081 gttttcgtca tagagcgtcc gggtacacag cttgttcatg taaccgctgt aatactgcaa
    16141 aacgcgctct acggctccgg catccccagc gcgggcggcc tcgatcaccg aaaggggcaa
    16201 aagctcaatg cccttgtagt tcgggttctt catccgcgtc taacctccct tcggcatcaa
    16261 cgcctttagc tgtttccgca gctccgataa ggtatttgtc ctgtgccgct gaacggcact
    16321 ccgggacatt cccacaaggc cgccgatctc accatctgcc atatccagaa cacagtgcag
    16381 gattaaaata ctctgctcca tgctgggcag cgcggcaaag gcttcggcaa caagctcatt
    16441 gttgatatgt aggtcatagc catgcgacga aaacgtaaag ctgtcgctgg ggtagtgatc
    16501 tactgtacag agcttgtcca aatctgcctg tgacaaagag cttagtgaca cttcacggtc
    16561 acggcggcgc ttcatttcag ccaagtagct tttggcctcg ttacgcagta ccgtcttgca
    16621 aaaagcatcg aacatgcacc gcgcttcata gtcgcggggg atagcatcca tcttctcacc
    16681 ccctttctgt gggggactta ggtggttctc tccctttccg ctaacaagac tttgacaagg
    16741 ccgccagcta cccgctaaat acctcctttt tgaaaatttc tcaaaaaatt tttttgggga
    16801 cagccgggcc gcaaaagacg acaaaaatcg cccggcaggt cgcaaaccta ccgggcgaga
    16861 aaatgctttg ctatgctgct gatttacatg gtatagtaca tactcataac cggaatagcc
    16921 ctgtggaggg gcaaggcttt ttttgagtgg tggaagtgga ttagagcatg gcaatagcaa
    16981 aacagcatag cggcatcctc ctatgggccg ccacaccttt tgctgccaga aaagaacggc
    17041 ggccttgatt tctcaaaacc gccgccagca aaatacaaaa tgggcgtggg aaaggtctgc
    17101 ccaacagcgg tttttttctt ttctgccgct gggcagattg aatactataa tttgcaatgt
    17161 attacaaaag atgctttaac cactttccag taaaagattg tccatgacca gcatagattt
    17221 tatcaaatcc aaaatctgat acaaaaccaa tactttcatt atgaaacggc aaaattaaaa
    17281 taggtatcgg ggtatggctc atcaatcaac ttatagtgcc accattcaaa gcgataagac
    17341 tgaaatccgc tgctttccat gattttacgc aagcatcttc gattttgtgc ctctgcatcc
    17401 cctatccctt ttgctgtatg atgcgaccgt tcgtccataa aatcgaagtt acttcccatt
    17461 gaaacaagtt cccctgtatc caggtggtag agcgtaagat caattgcgct tccacggcta
    17521 tggctggatt gtgaggccac ataacccttt gtaatcaact cggctcgctc tatattgggg
    17581 taaaattttt cttttgtgag attgtcctcc ggttgcgctg cccaacgcag gaagcagtcc
    17641 accgcagttc ttggccgata tccatcccat aaaagcaagc catagccaag cgcagccgca
    17701 tggatttgtg cctcgcgcag agcaaacgcc acggcctttg tgccgatgat gcgattcacc
    17761 tcatacccat ccaccggttt tcctgtgaag ttatcccatg tggcgtactt ggcatcccaa
    17821 cggacgccat gcaacatttc atctaaaaac aaaaaaccat tttccatact tatcacctct
    17881 ttaacgccaa tgtaatcagg ctgtcaatca gtgcaggaag cgtgattcct gcggcggcca
    17941 tcatacgtgg gtagcggctg tacgatgtaa aaccgggcag ggtattgacc tcatttagaa
    18001 cgatgccgcc atcctcctgc aaaaaaagat caacacgggc aagccctctg catccaagca
    18061 cccgatatac tttctttgcc gtttcctgca cccgatttcg ttcctcgacc ggaatgtctg
    18121 cgggaactgt aatcatcgca ttttctgagc ctttttccgg ctcgttttcc tgatggatgc
    18181 ggaaggtacc gtggctcagc cggatttgat ccacttcgcc gacaatcaaa tcatcctcgt
    18241 tccccatgac cgcacacccg acctcacagc ccgaaatcgc ttgctcaatt aagatttttc
    18301 catcatattg tcctgccgct tctatcgcag cgttaagttc ttccgtaccg tttactttgg
    18361 ttacgccaaa ggacgaacct gaccgtgccg gcttcacaaa gacagggtag gtaagcgcac
    18421 ccgcctccgg cttgtcacct ttatcaatca tttgaaattc gggaacggcg atgcccgcat
    18481 tttttgtaag aatgtaggcc agtgatttgt ccatgcaagc tgcggagctt tgaatatcac
    18541 agcccacata ggggatacca gacaatacaa acagcccctg tatcgcacca tcctccccgc
    18601 atttgccatg caaaaccggg aaagccacat caatacgccg tgtttcgtat tcgctttctt
    18661 tcatgacaag cagcccatgc gttttcctat ccggggagag tatggcgggg agactgtcgg
    18721 cttcccattc cgtacatggc ttcttgcata gcttccatac accgtttttt gtaattccga
    18781 tgtagtgcgg atcgaatttt tccgtatcaa tgttcgcagc aatttctatt gcggatttta
    18841 ccgacacatc atgttcctcc gagcaaccgc cgaagatgat tgcgactttt attctattca
    18901 tgctgtaaac tcctttcaaa attgagacaa ttcctgattg ttttttctgt agtatcctgc
    18961 agcacacgct cagtgtagta cgccgtatgg ggtgtgatga tcacattcgg catccttaaa
    19021 agctgcgaca aaaagggatg gtcaagcact ttctgcgagc aatcggtata aacaaactga
    19081 tcctcgccct ccaacacatc cagtgccgca ccacccagct ttccgctttc caacgcctcc
    19141 accagcgccc cggtatcgac aagcgctccg cgcccggtgt tgattaaaaa tgcgccttgc
    19201 ttcatctctc caatttgctt ctgaccgatc agatggcggg tatccgcaca aagcggcaca
    19261 tggagcgtaa caatatcgct gttttttaga agctcatcaa gctggacata atctgcatcc
    19321 atttttcggc tgttatcata ggccagcaca tggcatccaa atccccgcag ccttttgacg
    19381 accgcttgcc cgatatggcc ggttccaata actcccacag tcatatcccc cagttctttc
    19441 ccccggatac gatccaatct gaaatcttgt tgcgccacgg cgtgcatggt gggttttgca
    19501 ccccgtatgg ccatcagcat cagcatcaaa gcataatccg caacgctgtc cggcgaatac
    19561 gcaaccgtgc caaccgagat tcccattctc tcggcggcag tcgtatcaat gtgatcgcag
    19621 ccgatgctgc gggtagaaat gtattttacc ccgacctttc tcagcgcaag aattgtcgcc
    19681 tcggaaacct cggacttatg gcctacgcta acgcattgat tgccagcggc caattttgcg
    19741 ttgtctgccg atatcgcatc gctaatcagc gtagggataa tatgaaaatc cggcgataaa
    19801 gcgcggaaag catttgcctc atcctgttcg catccaaaaa cagtaatgcc cacacttttt
    19861 ctcattggtt ctcctcctga atatccacac tttccgggag gggataacag attttgcatt
    19921 tgtttgtata aagcagcttg caatctatta tttccccggt acctaaggca acttgcatcc
    19981 gtttaacctg ggcatattca taaatcccgc cactttcacg gacatactgg atactgccat
    20041 ttgtaatttt gtataatgct tggggctctt tgtcggcgga cacctgaccg atgattttct
    20101 catcatctaa ggtcacccat atttggtagg tgcagtcggt atcgtttcgc acttttaaat
    20161 caatccagcc ctctgaaatg gttgcatcca cccctttaat ctcgtcactg tttggctctg
    20221 gaaactcctt tacttcgtga cctctgcgct ggataattgt caatggcgta tgcaggaaca
    20281 tccaaaatag taaattgctc atctggcaca taccgccgcc cgacatggtg gtgagtttac
    20341 cattggtcac cgtaaggccg tctttatagg gggtatcttt gtccgcatgg cgtaccagcc
    20401 accagaaaga aaagggttcc cccggtctta tcaataagcc gtttaaggtc tttgctgcca
    20461 gctttaagtt gaacaccttg ttttcctggt atatcatgtc aaatccggta ttgtggttgt
    20521 ataatgcgca atccgtttca aagagcaaat gggaaagcga tttttcccct atcgtctgcg
    20581 catagcgaca gccgtcaaat ctcattcccg cataaaagca catttttctc tgcgcccgtc
    20641 tcattggaag caggaacggg aaacgctgtg tcaatctttt tctgtccata acataacatc
    20701 cttttctcat ttttctggtt ttaaatattc ctcaaggcaa accccttggt tgtacatctc
    20761 tgtggcagct tcgatgccaa catatcggta atgccacggc tcgttgctca caccggttat
    20821 ctctgtcttg tctggtgggt agcgacgaat aaaaccaaaa cgatagctgt tttcatccag
    20881 ccatctataa acctcgttgc ctgttgaatg aattccgtcc gcattgatat ccacagcaag
    20941 accaagctga tgctcgctcg ttcccggcac ggccacccaa gtttctgctt ccgctttagc
    21001 ctgtgcagag gtgtagcctt tcgccttata ttcggcaatt ttttcatcca taatttcttg
    21061 ctgtttttct gttgttcggt atccggatgc gacaatcggg taaactccat cagttcttgc
    21121 ggcatcaaac aaatcttgaa gatagggaga aatccgaata tctatccgct caccatttga
    21181 tagttgctca agctccacat cgtactgtgc ggggatgggg ttctgcctgt tcactaaaat
    21241 caggctccat tcctgttcat ctccctgttc tttggcggtg gcaagagcgt tttcctccaa
    21301 attctccact acgtcagtgc tgctgcctgt atgagttgca gggatgggcg gtatctgtgt
    21361 tgcctccaat acggaagcca gtctccgccc caaaaacagc gtgcagactg tgaacgaaat
    21421 aatgaacgca catagaaaag cccgcttttc cacggattgt ttcatatgcc gtttgtgatg
    21481 atccgcattg gaatgatagt tgcttttttc catttgatcg aatgcctcct ttgcaataaa
    21541 actacgattt gtggctggta cgattgttat tatggcaagc gcatctgtac tttccctgta
    21601 gccagtctgt agttttcctg tagcagcaaa aaaagaccgg cagggttata cctgtcggtc
    21661 aaaatcattt aagttttaaa tatttacaat gttgatgtga gcggtaaatc cagccagaac
    21721 aaaacgccat ccgaggtgtt ttccagcgca tactggaggc tcatggcatc cagcgttttt
    21781 tgtacgatgg caagtcctaa accgcttcgc ccactttttc tgctttgcgc ctgatcaatg
    21841 cgatagaatg gggtgaacag ccttggaagc gcagtatcat caatgtgaac gcccatgttc
    21901 aaaacaaaaa ggcggcattt ttcagcacca ggctcactcc atatccgtac ctcgcctccc
    21961 tgcggcgtgt tctgaactgc attcaatatg acattggata gtgccttttg gagcagcctc
    22021 ggatcggaca ggacaatttg cccggctgga atatctgtga cgaaccgctg gttgtttgcc
    22081 tctgccaagg tttgaaaatc gggcagcaac tcggcaaccg tgcgccctat gtccaacggt
    22141 tcagctatgg gtacgattct cccatcattc aggctgacaa gctccagtat ttcggaaatg
    22201 attttgccct gcctatccat cattttgatg cattcgcgca gatacttaga atgatctttg
    22261 tagtcaccga tattttcaag cattccctcc aacagaacgc ttgtagccgc gatgggcgtt
    22321 tttagctcat gagaagctgc cgcaaagaaa tatcgctgtg tttcctccaa ctcatgttcc
    22381 cttgcgattt catcctccag ccttgcgatg gtttctttca gcctgacata catggaatgc
    22441 atatcatgag ccagtgcgcc aagctcatcc tttcgctcca gcggcggcgg tacatctttc
    22501 aggtttgcca ttttattcgc actgtccgct aaggctttga tcggcgttgt catttgccgc
    22561 gcaaagatat acgcgcataa aaggctgaat acaaccatta tcgcaatcat aacaattccc
    22621 cgaattgtca gcccttgata aagcaatccc acacctgcct tgctttgagc aacaatcgaa
    22681 atattatcat ctctatgtac cacataaaga aagtcgggtc taaaactatt tgatgtattg
    22741 gcatttggtg tggcatagag tacgcttccc tctttatctt caatataaaa ctcaaaggat
    22801 tggttattgt agtgaaacag ccctgccacc tcttgaatat caagcctatc gctattctga
    22861 atcagttcca ccaatggctg ataggatttt actgtttgct gtaattccat cactctgaaa
    22921 taagacacaa attgctgtgc aaacagtgtt gctgttacac cgacaagcag tagcagggca
    22981 atgatcgtat aggaaaaaac cttaatgaaa atcccttttc tttccattat tatgattcct
    23041 ccaatcggta tcctacaccg cgaatggttt tgatgatatt ttccggcagc ttggcccgca
    23101 aatttttgat atgagtgtgg actgtgctgc catcaccctc aaagtcatat ccccatatac
    23161 gtgacaaaat gatttcatgc gttaaggttc tgcctttgtt ctgcaccagc agcaaaagga
    23221 tttcaaattc ttttcgtgtc aggggcagct ctgtaccgtc acaaagtacc gtgaaatcct
    23281 ccggcagaag tgtcagcctg ccgacacgga tttcctttgc cagcgcaccg ctgcgccgca
    23341 gcagggcttc cacccgcttt agtaaaatct gcatcttgaa tggctttgtt acatagtcgt
    23401 ctgcctctgc atcaaacgcc cggatttggt tttcgtcatc cgacagggct gtcatcatca
    23461 gaatgggagt atcatttttc gcacgaaatt cacgcaaaag ttcatgcccg ttcataccgg
    23521 gcagcataat atcaagaata accagttgat aagtgttttc gtaaaacttg gtgtatgcct
    23581 catttccatc tgtgcaggca tccacctgat atcctgcctc agccagaaac gcccttactg
    23641 tattacagat atgatcatca tcctcgacaa gtagaattcg tatcgacata aaaatccctc
    23701 cattttaaga agataacata acagtctgta gtttccctgt agtttcaaag cgatttcttt
    23761 tcggatttta atcatccgtc attgggatac tcgcttcttt tcatggtgta tgtatctata
    23821 ttattggttt aaacgaatta aatcaagata ataataatta acaccttctt aatgtttggg
    23881 atgtttcgat tacagcggtt gtcaaaacat cccgataata ctggcaagca atggatcaga
    23941 atatccttta cggatattct gatccaccac ttgcccgcct gcggcgttct cgttttgctt
    24001 gttggggaca ccccaagcct cagcaaaatg cgcggcctct tttttgcgaa tgcaccttgc
    24061 ggtatggctt ttcacacagg cagggcctgt gtgtactccc tccggtcgct cttgccgcac
    24121 tccgcgcagc agattcagtc ctaataccgt tcaagacagt agaaaatcag caagtctata
    24181 ttcctcatat cttcatcatc cgtgtccttg cagttacagg aaatgtaata atcgccaaat
    24241 gtaaatccca gaatattttc ctcaaaaagc cgtacctccc cggtattaaa atcaatcacc
    24301 ccatactcaa aggcgcatta gaccagcagt tatccaatgt ctggagactt caccataaag
    24361 aatccagatg ccggcctttt caattctacc atatacggct gatacagcag cagcttcctc
    24421 gtctttgttt cgggcatttt ccatttctgt catgataaag tttcgcttct tcatacatcc
    24481 atgtgtaaat cttttctttc tgtttcagat gagaatactt tttatcggtc tggagcagcc
    24541 tgccatctat catcttatag tttttccgtg acaaaatacc atgctttctc tctcttcaaa
    24601 accatatcca aaatgcgccg gtttcattat actattcagt aaccgccttt cctttctttg
    24661 tacgcctgtc aatcggcttt tccgcagttt tgggaatgag ccagatcgtc gccatcttta
    24721 cagcgccggg gatgcgtccc gcagcacaat agtagtttat ccatcgtggg ggcacacccc
    24781 atttctcgcc tgcctctttc aacgtcatgt agtccatagt acacctccac agggtacatt
    24841 ataattcttt tgctcgaaga ataaaagaaa caaaatgtga aatataaact ttaagaaagg
    24901 tgcatatacc aacattccac gggcagagta tgaaatatac aatgtaagtg ggaggtgcga
    24961 tatggcgaat attgaagatt gtcccggctt tgaaactttc ggcgcggatg tgaaagcggc
    25021 ccggcaagca aagcgcgttt cgcgcaaagc aatggcagag aaaataaata ttgactggcg
    25081 ctatcttgcc aacatcgaaa acgacggggc cattcccagt ctgccggttg tcatacagct
    25141 tattaaagcc tgcgggcttc ctgtggaacg ctactttaac ccggagatca tgcgggagga
    25201 aagcgaactg cggcaaaggg tcagccacaa gctgaaactc tgccccgaag aatacctgcc
    25261 gatcatcgag ggcgcgattg acagcgccat actaattgaa aagccgaaga agaatgaaac
    25321 ggaggatgtg taactggcat cctctgtttt acttttagcg ggagctgcac agcgtagctt
    25381 ctattttttt gcactttttt ctttccagag ggctattttg cgggtagttt ggggctttgg
    25441 aaacgtcttg ttagtggaga aacagtaacg tagcaagcat agggagtgta gccactcccg
    25501 gaaaaacggc ctgccccgtc cctgccgggc cgcgtccgtt ttgcttgttg gggaaatccc
    25561 caaacccctg aatggaaagg acggtgaagc atggcaaaca gaaagcgaaa aatcgtgctg
    25621 cgcgtccctg tgacgccgga ggaacgggct atgattgaac agaaaatggc gctgctgcat
    25681 acgaagaact tttcagccta cgcccggaag atgctcattg acggctatat cgtcaacatg
    25741 gacaccagcg acatccgggc gcagaccgcc gagatacaga agatcggcgt caacgtcaat
    25801 cagattgcaa agaggctgaa cggtatgggg ccggtgtacg cacaggacat cgaggatata
    25861 aagggggcgc tggcgcagat atggcagtta caaagataca tcctatcaag tcaacgctga
    25921 aaaaagccct tgactacatc gagaacccgg acaaaactga cggcaagctg ctggtggcct
    25981 cctttgcctg ctcttatgaa acagcggaca ttgaatttga aatgctgctg gcgcaggcat
    26041 accaaaaggg caataatctg ggccaccacc tgatacaatc ctttgccccc ggcgaagcca
    26101 cgccggaaca ggcccatgag atcgggaagc agcttgccga ggaagtgctg caagggaaat
    26161 atccctatgt gctgactacc catattgata agggccacgt ccacaatcac attattttct
    26221 gtgccgtgga tatggtaaat cagcgcaagt acatttccaa caaacagagc tatgcctata
    26281 tccggcgcac cagcgacagg ctgtgcaagg aaaacggatt gtccgtggtg aagcccggcc
    26341 agagtaaggg caagagctat gccgagtggg acgcccagcg gaaagggacg agctggaaag
    26401 cgaagctcaa agcagccatt gacgccgcta tcccgcaggc aaaagatttt gatgatttcc
    26461 tgcggctcat gcaggcgcaa ggctatgaga tcaagccggg aaagtttatt tctttccgcg
    26521 ctcccggaca ggaacgcttt acccgctgca agacattggg ggaagcctac accgaggaag
    26581 ccatcaaaga gcgtatcaaa ggccgcgtta tcaccagagc gcccaaagag cgcaagggga
    26641 tttctttgcg gattgatctg gaaaacaaca ttaaggccca gcagtcggca ggctatgaga
    26701 ggtgggcgaa gctccacaat ttgaagcagg ccgcaaagac tttgaatttc ctgactgaac
    26761 atgggataga cacctacccg gatttggaaa gcaaagtggc cgagatcacc gccgccagcg
    26821 acgaggccgc cgctaccctc aaagctatgg aacaccggct tgcggatatg gcggtgctga
    26881 taaagaatat ttctacctac aagcagctct ggcccgtggc tatggaatac cgcaatgcag
    26941 cggataaggc aaaattccgg cgtgagcatg aaagcacgtt gattttgtat gaagctgcgg
    27001 caaaggccct aaagggacag ggtgtgaaaa agctccccga tctgtacgcc ctgaaagccg
    27061 agtacaagcg attggccgag gaaaaggaac ggctgtatga gaagtacggc gaagcgaaaa
    27121 agcagatgca ggaatacggc atcatcaagc agaatgtgga cggcattttg cgtatgacgc
    27181 cgggaaagga atggacgcaa gagctatgag tattccacga atgaattacc ctcaatatcg
    27241 caaggcccgg aagctgacgc atgagtgctg caactattgt gacggcaact gcctgttgct
    27301 ggacgacggc gaagaatgta tttgcgtaca gagcatttcc tattcgcttc tgtgccgctg
    27361 gtttaaggcc gctgtcctcc cgctggatgc ggccctgtat gccgagatca ccaaagaccg
    27421 ggacgaagtg aaacgctgct gtgagtgcgg ggccacgttc acgccgaagt ctaaccgggc
    27481 caaatactgc gcggcctgct ccaaacggat gcgccgccgc aaagaggccg agcgccagcg
    27541 gaaaagatac tggaaaccta cgcacttaga gctgtaaaag cccttatatt tcaaggcttt
    27601 tccggcatgg tcagcggggt atgtgggtgt tttatcctat ccccgccgaa gtgctgttct
    27661 aaatgcgtag aatttaccag cagaaaagcg ccgttttctc tggttccatg cttccgaata
    27721 tggtatcata gaaaaaatca gtctgacggg ggtatcagga tggacggaca agaaaagctg
    27781 ctggactatg aaacgatcaa agccgccgtt gccggtgaga ggtgggccac ggaaaaagtg
    27841 ttggcccatt atgctgacta catcaacgag ctttccacgg tggagatcag acaggcaaac
    27901 ggcaaaaaga agaaagtcat tgacgaagat atacggcagc gcatttccct gaaactgctg
    27961 gaagcattgc cgagcttccc gctggaacag agatagacgg caagagggct gcaccctctt
    28021 acgccgcttt gcggctatca cctgcacacc cctgaaacag atacacccgc tgcgcggcta
    28081 tatctgtttc aggggtctaa ttatagctgc aacctacgca tttaagggat tgaaaaccgc
    28141 ccgctgcaag gcttctcccg catgtttgca ggggcaagcg aatacttcat cctatccccg
    28201 acaataccgg gttctaaatg cgtaggaata ggcaaaaaga aaagacgccg gacgcaagcg
    28261 accacatggc cgccgcgccc ggcgtctgct gttcgttatt cgtctgtgaa gtggaacttc
    28321 tggccgtcat agtcggcatc cgtcatgcgt tccagcttgg aaagggtctg ctgggcctgc
    28381 gcccgcatat ccccatccat aaccagcatg acggcggtga gcctgtttat cgttctgcgc
    28441 cggtctgcat tgtggtacat acagatcagg ttttcttcct ccacggtaaa gtgcatcatt
    28501 ccttatacct ccaattcatt ctttttggtt ctggccgccg ccttttttgg gctggcggcc
    28561 tgtttgctgt cggatagctg cttgcggata gagggccggg gcctgcgaat actcacatcc
    28621 cggcgctcgt cccggttaat cacggcatac acgccatgcc tgcctttcat cccggtaaaa
    28681 cacagggatt tatagggcag catggcaaag agccggtcat tatccttggt ggaagcaatc
    28741 gccgcaaagt gcggggagat ctccaccatg aaatgcgttt tattggggct gttaggcgcg
    28801 gacagatctt tcaggctgtc cacaatacgc cgggcctcgg tttcaatccg gctgtcatgc
    28861 aaagcggtga cgtggacttt gaaatcgccg gggacggccc gcccccggct gtgctgctcc
    28921 gtccgtagcg cctcctgcag cacagccggg tcatggggct gggcctcata gtacaaaaag
    28981 tttcccaata cccggtcagg gcttccgtca aaacgctggc tctccgggat gtcacgggtg
    29041 ccatgctcat aaaagagccg gttcacactc accggctggg cggtttcaat gacgtgccgg
    29101 aaatgctgcg gatagtccag ctcatagaga ttgccccgga tagtgccgcc ctgtgtgccg
    29161 gtcagctcca ccgcgtaggc cagtatcttg tcacgggtct gctccccgta aaatttccat
    29221 gtgttgtact gtcgggtgtc tttcaggaaa acatcacgtt cccggaaaca gtacgtcccg
    29281 gagggccggg acatccagag cagggtcttg tctgcggcct gatcgctggc ggcatcccgc
    29341 ctgataatgt ctttgtcaat gccaaagtca ctttgataaa acgcggtgtt ctgccgcatg
    29401 atctgttcca gcgcggccag aacgtccaca ttttcaaact tctgcattta ctctacctcc
    29461 aatccctttg atttttcccg cgccggtggc tgcttggcct gttcggtctt ggccgcgttg
    29521 agctgcgccc ggatagaggg cttttctttc tccctgcggg ccgcaagctg taaggcgctg
    29581 ggcttttcgc cggaaagggg ctggatgcac ttgatacggt cagcgacgcg gattgtggtg
    29641 tcgtttaact gccgctgcca tgccccggcc ttgggcgacc agcggaaacc gttgcttttc
    29701 agctcgtcgc gtacagcagc atccggcttc ccctcaaaga agatttgcag gcggttggcc
    29761 acccggttga tctccacagt gccgccgtca aactcccatc ccacataggc cgcctccttt
    29821 tggcgggtca attcctcaat gcggcccttt aaccggcgta tctcggcgtt attgttggag
    29881 agctgccagg actggaacgg ttttttctca tagtgccagc ccgacgccat atccgctttc
    29941 aggttttcaa tgcctctttc ggtcagatgg gggcatccgt ccagcgtccc atgcttgcgg
    30001 tagtaggcat tgacggcctt catcaactcc tgcgacgctt ccagcttttc cagtttcttt
    30061 tccagcttgg aaacggcctg cggatcgtcg gcgctgatac cacccatgcc ggtgctgcgg
    30121 attttgtcaa gcaagccctg aatgtactga aattcctcca tgttgcggtc actggcggcg
    30181 ttctgctttt ctttcgcccg taccgggaaa ttggacggcc cggcaatcag gacagagggg
    30241 acgcgggcgg taatctcata gcccttattc atgttctcgg ccagcttgcg ggcgtaggtg
    30301 tcaaggaggc tgtctatctt ttcgtgatac tctggctcca cacgcttttt ctggcgctcc
    30361 gcaatttcca cggcctgatc gacatagtgc cggtattccg ccgtggcgct gccgggccgg
    30421 tagtcagaaa agctcatggc ttccttggcg cggcgggcgg ctccctcatt gatgggataa
    30481 tagcggacag ccgtttgcgg gggcgcagcc tccgggggtt cctcctgtgt ctggccggaa
    30541 gcaactgcca catcctcaaa agatagctgt tcgggttcct ccggctgcgg ttcgggcggc
    30601 gtattgttga taatgccgtc aatcatgttt tcgttctgct ccgtagacag ttcggcggta
    30661 cgcaggggat tttcccgcaa aaactccggc acttccatat agccgaagct gtctacatag
    30721 tgggcggtgt cctgtccatt ctggtgcagc accaccacgt cggaaacgga aaggctgtgt
    30781 cccctaaaat ctgccgggtg gtcgatgttg aatgtgcggt aaatatcctc caaagacgtg
    30841 cttttatcca gcggtgccgt ataaacaagg tcatagttgg cactgtccac ggccagccct
    30901 gcggcctgta aacgctcgta tggctcaaac cgatagtcgc gggtttcctc cccgcctcga
    30961 agctggtaga tggaaaaggt gtcctgttgg ggtgcttcat agccagccgc cgcgtattcc
    31021 tccacggtca taccggctgc ggcggcctcc tgcgcgatct cggcctgtac ctgtgctttg
    31081 tagtcctgca agctctggtc gaagtcagcc agtttcggcg gctccggcaa ctgatactgg
    31141 ccctgattga gcatggggcg gcactcctgc acataagaga gaagcgcccc caaataggcc
    31201 gtttcctccg gcgtcagggt ttccccggac tgtaagcggc cctgcgccgt ctgttccatt
    31261 tgggcaaggc tgcaatgcag cttcatatag gggacaaact cgcctaacag catatcccga
    31321 tgggccttgt cctgctccca gccctctatg ccggttgtag cgattacatg ctttttccag
    31381 ttttcgtcct gcgcgtaaaa ttggtggtag ctctggatat gttcgatcag ggaaccgtcc
    31441 ctatctccaa aatcctgccg cccctcgtag ctgtccggct cgccctgaaa gatacagtca
    31501 atgcggaacg cggttttgtc atagcctgcc tctgccggat atgctgcatc cagacgggca
    31561 aacagcgcgt cggcctcatg caacggcatt tgctggccgt cctttagctg ggggctttcg
    31621 ctccatagca cagtcacaag cggctcggct gccggatcaa gggccggggc ctgttcttcc
    31681 tcggcctgcg ccggggccgc tgcctccggg gtaacgtcaa ccgtgacggc ctcctgttcc
    31741 tgccgggcct cgcgctcctg ctgaagctgg gcaaaatggc cgtcgatctc ggttatcaat
    31801 tcgctggccg tggcccggat ggtttcaagg gaggctttca gctcggataa ctccctgccg
    31861 ctgctccaat cggccacata gccaaaagaa tagtccgacg tgtccagccc gtaatactgg
    31921 cagacggtat aggccacgct ttcggcctgt acctcgcggg tgctgcggtc tggccgggcc
    31981 gcctgttcct cggcgggggc ctcccggtca atggcgtgga gcttggcatg ggcaatctca
    32041 tggatggcgg tctttagggt ctgcaattcg ctcatgccct cgttgatggc aatgcgctgt
    32101 tttgcgtaga agcagcggcc cttggccccg tctgaaatcg gctcaatgct tatgggatag
    32161 ggtgatgtcc gttccagcgc ggcaaagaaa tcctgatact gctgcacgtc gccggtaagt
    32221 tcactgatat agggcatggg aaaatccttg ccctcggtct ggctgatgtc aaagactgtc
    32281 accaccttaa aggccggaac cgtcacttcc tgttcttcgg tcacgggctt gccgtccgcg
    32341 ccgatcacgg gctgctgggt ggccgggtcg attttctcca tctgctgctt aaccttgaac
    32401 ggggccgggg ccagtatctt aatgcctttc tcgccccgct tcacatggcg gtcaaattca
    32461 tcctgccacc tgttatagcc cgccacaatc gaaccgccct gcatggcgat cagcagcgta
    32521 ttgttcagac tgtaatcgtg catcttggac atagcggata agtaagccat atagcggcta
    32581 ctttcaaaaa gctcctgtac gccggtttcc agacggtcag taatcacttt catgcgttct
    32641 ttgctgttca tgccgtccag catgatcggg ataaccgggg gcggcgcttt gtcggggctt
    32701 tcggatgcct ccggctgctg ggcctgcggt tcctcccggt cagcttccgg ctgggggtag
    32761 tgcatcaccc ggtattcctc cggcaccggc tggccctcat ggacgcgctg ccattcgtcg
    32821 ccgcttctca ccagatagcc gtactgggta aaaacgcctt gttcctgctg ggcaatgtgg
    32881 cgtccaaact gcgccgtatc aatcccggct ttccattcct ccggcatatc caccatgccg
    32941 gaacggttca ggtagtagtc gcccaactgt ccatcccccc taacgtcggg aagatgcaca
    33001 tagtaatcca cattttcggt gtagtcgatg atctggccga tattctcaaa gccgccacgg
    33061 ggattttgca gggcggcgtt cagctctgcg atctcggcgg cgtcaagctg gcccagccgg
    33121 gcggcaagga aattcagctc gtccacgtcg gcggccagca ccatgtcata gggaatggca
    33181 aggtgtctgt cctccgggca ggaatacccg ttgataaaaa aatcctgcgg attgtcggca
    33241 gtaatgccaa catcccgcag ggcggcttgc agcgtttcgg ttgtggtggg caaatccagc
    33301 cagacgcctt gtttgccctg ttccaaaaac tgccggttat ggacttggat agaaaatact
    33361 tcgttcacgc ggtcactcct ttctctgttc tgtttcaaaa aatagggggt tggggacttc
    33421 cccaacaagc aaaaatcccc ggcccggcag ggacgcggcc gggggatttt accgggagtg
    33481 tagccacact ccctatgctt gctgtgttac tgtcctttag ctcctgtgtt caatgcggta
    33541 gttgacgtac ttgcccccgg tatcagccaa aagcaccgtc ccgtcgtagg ttttgccggt
    33601 ctttacggaa tagaggccct ttaccttgac tttgccggtt ttgagcagcg cagcggcgat
    33661 cttcggggtg aacgctttct tgcgttcctc aaaaaatcgg tcattcttcc acatgacgaa
    33721 ctggcaggcc cggtttccgc agtagtagtt tttcttgccc tcatagacag cctcaccaca
    33781 gcggggacac gtcccgatag gaacacgctc ggcctgaaac aatttctgct tttcctcact
    33841 gatacaggaa taggtctgca ccagctcccg cgcctgcgtc tcgatgccgt ccataaattc
    33901 gtcaggatcg gcctgcccct tggcgatctc ggtcagccgg ttttcccatt cggcagtaag
    33961 ctggggagaa gtaagcgcct ccggcagcac cacagccaga ttgatgccgt ccttggtggg
    34021 aatgagctgc ttgccttttc tctggacaaa gcccatctgc accagctttt ccagaatggc
    34081 ggcgcgggtg gccggtgtgc ctaatccctt gcgctcggca tcctccggca tatcctcggc
    34141 cccggcccgt tccatagcgg acaaaagcgt atcttcggtg tagggcttgg gcggcgtggt
    34201 gaaatgctcg gtgacagagg cggccacgtc tgcaaaggtc tggccctcgc aaagctccgg
    34261 cagctcccgc accgcctcgg cgtcctcgtc ggcgtcggtc tttaaggaag aacggaaccg
    34321 gcgttcaatc tctttccagc cgggggaaag gacggtcttg cccttggcgg taaactcctg
    34381 cccggcacag gtaaatgtgg cggtgacggc ctcatagata tgcggcccgg ccacggcaca
    34441 taagagcttg cagcagatca gggacagcag ctttttttca ctctcggcca gagtgccaaa
    34501 gccctgcttc acaaattcag cggtggggat aatggcgtgg tggtcggaca cctttttgct
    34561 gttcaggatg cggtcaaact gcggggaaag gttcaggccc ttggcaaacg gcaccagctc
    34621 ccacaggccg gacacaaggc tttccacggc gggcagcata tcgtcggtaa gatattgact
    34681 atccgttctc ggataggtca gcagcttctt tagatacagt gcctgggcat agtcaagggt
    34741 ctgcttggcg gtatagccga aaagccggtt agcctcccgc tgcaaggtgg taaggtcata
    34801 gagcttgggc ggctgttccg tctttttctc ccgcgtcacg gaaacgcaaa cggcctgcgc
    34861 ttttgcacaa gccgccttga cggtgtttgc ctcggcagcg tcggaaaagc ggctgcttac
    34921 cgcgtccgcg ccgcccgccg tgatatggac gatgtgatat ttctctttct tgaaatcggt
    34981 aatcttggcg tccctgtcca ccagcatttt taaggtcggc gtctggacgc ggcccacagt
    35041 caggttcttg tggtacagga cggaaaaaag ccgggtggcg ttaatgccga tcagccagtc
    35101 ggccttggcc cggcacaggg ccgattgata cagcggatca tagtcgccgc ccggtttcag
    35161 gtgggcaaag ccgtccttaa tagcactgtc ctccatagag gaaatccaaa ggcgctcaaa
    35221 gggcttttgg catcccgcca tctggtagac gaaacggaaa atcaattccc cctcgcgccc
    35281 ggcgtcggtg gcgcacacaa ggccggtcac gtcggggcgc tgcatcagcg aacagagaac
    35341 gtcaaactgc tgtttcttgt cgtcggggac gatgtactgc catgtttccg ggagaatggg
    35401 caaatcctca tagcgccatt ttttgaaacg ctcgtcatag cgtccggcgt cggcaaagga
    35461 caccagatgt ccgatgcacc agctcaccag atagccgttc ccctccaaat agccgtcgtg
    35521 tttctccgtg gccccgatca cgcccgcaat gctgcgggcc acgctgggtt tttccgcgat
    35581 tacaagttta tatgtcattc ctcgtcctcc tgttcactca caaaatcagc ttccgggtca
    35641 aactcggttt cgggttcctc gtcctccaaa tcctcgtcct ccccaaaatc atactcgccc
    35701 aaatcgtcgc tgccggtggt ttcagccttg ggctttttga acttgaaata gtaaagggcc
    35761 gcaccgccgc ccgccagcgc caccagcagg aacacgatca ggccgcccgc gccgcccttg
    35821 ggttcttcct ccggggcttc gggttcctcc ggctggggtt cctgcggctc cgggccgctg
    35881 cactcggtca ggttggtttt acataccggg caattcgtgt tcacagcccc ggccttgcat
    35941 ttcgtggtac aggagcagac agcagcgggg gtgacggttt ccccgtcctc catcagcgtc
    36001 agcagatcgg cttcatccac ctgatttaag aaatggacag tttcttttcc ctcgtcgtcc
    36061 cggtcaataa tcagataaaa cacattgccg tttttggttt ccacggtgat aaactgcttg
    36121 ccatttttcg cggcgctgcc gatgtcgtca atcagtgaca ggttcccgtc cggggacagg
    36181 gcggcgctgg ccccgccgcc attgaacagt tccagcagag aagcaatttc ctccgggtca
    36241 atggagaggg aaaaaccgcc ctcgccggta gccgctactt ccttttcgct gacggtcata
    36301 tagtcggaat ggacatagcc gatgcgctcc ggcaagagaa ttttaatcca gtcgccgtct
    36361 gtgccgacta cctcaaccgt cgtcccattg ggaagctggg tgaacgcggt cttgtcaagc
    36421 cccgcgccgg tgcggacatt cagcctgccg ccgttggtgg tgacggtgcc ggtctgttca
    36481 ggttcttttt tgtcggtgcc ggtggtgatc tggatgccgt cgtccgtggc ggcaatgctc
    36541 accttggaac cgaacagcgc ggaaaacagg tcggtgatgt ccttgccggt cagagggccg
    36601 gtatcttttt cggcctcggt ttctgtcccg tccgtggcgg tgccggtttc gtctgtttca
    36661 ggctccaaac cgcccgtagc gggttcggtt gtagcctccg gcagcggggc cggtgccggg
    36721 tcattgccgc ctgcaagggc ggtaacggga aaggccgtga cgcagagcat cacggccaga
    36781 agtgcgggga gaatacggga aatccgtctg gtcttattct tcatgggcat tgtcctcctg
    36841 ttcatggtaa ggggttgcgg caggggcggc ctgcattgcg ccgctgcgta agaacgcggc
    36901 aaattcctcc ggcttcatgt tcatgccgcg cacaagctgg atgatctgca aattctcctg
    36961 ttcggttttc tgcgtttcca gctcccgaag ctgtttctga aactccgcga tcttagactt
    37021 ggttttctgg atgtcctttt cgatgcggtc aagtttggtt gccataattg aaagctcctt
    37081 tctggcgtta aggtaaacgc ccgtaactgt aaaaatggga ttgccagtag tttgaagtaa
    37141 ggttcgtgta ggaaatcggg ttcccgcaat gcagcatcac attgttgccc acatacaggc
    37201 cgacgtggga cacgccgggg gtgtcgtagg ttcccttgaa aaatacaagg tcgccgggct
    37261 tggcctgcga actggaaaca ggggtgcaga tgttatatag gccctgcgcc cccagccgtc
    37321 ccacgttcca tccactatga ttgattaccc acgaaatgaa gccgctgcaa tcaaagctgg
    37381 tgctgggaga gctgccgccc cacacatagg gataaccgat atatttttcc gcctctttga
    37441 gcatggcggc aaaggtggca tcctccaaag cctccggggg tacgtcgtag taggtcggcg
    37501 gcgtcagggt ggaggcgttg gggtactggc tgccggaaaa cagatcaggc cggtctccta
    37561 gcgtggacat atacagggaa tagaaactta gcgtttcctc gtccatgata tagactggca
    37621 catgggacag gtcgaagttt tccagcgtga cgtagcagat gtaatagtca tacggcactt
    37681 ggtaggtgtc tgtatgggtg ttgccctccg cgtccgtcca tgtatcggtt tcggtgcggt
    37741 aacgggtttc taccacgacg ttttctgtca ggatatattg cttgtcaaag agcatggaca
    37801 aatcaccctg tacctccccg atggtaaata tcccgtcatg gagcgccgac aggatggaaa
    37861 tcagcacata ggggtcatgg ctgatctcgt caaggtcaaa atggtattcg tcatagtcat
    37921 gggtggcctc gtagttgtcc agatagtctt gcagctcggc ttccagctcc gcgtaggcgt
    37981 cctcggcggc caacatatcg ctatcctcgg aaaagtaaga ggacgccgtg atgccgcttc
    38041 cggcgctgcc gaacatggcg gtgcaggact gtaagccgcc gatgataagc agcatcaaaa
    38101 gccccaacac aaggacggcc agcgcccctt tccagtggcg ggccacaaag gaggccgccc
    38161 gttcactttc tttggctgcg gccttggccg ctttcgtgga ggccccggct gtcttggccg
    38221 cgccctgtgc cgccgcgcct gcggtctggc ccgctgtccg ggcggccttg gcgtactggc
    38281 gcttgatctg ctgtttctgc cagaaccggg aaatggggtt gctggccgcc tgtgcgatct
    38341 ccgggttatc ccgcaaagat ttctggtaga aatactccgc gttggcagac aatagcctgc
    38401 gctcggcctt ttccgcgtcc cagtagggtt tcagcctgtg gtgccggatg gtgctgcgga
    38461 tggcttttcc ggcctgccgc tcggcaagtt cctccccctt atggccgccc tccacaccca
    38521 cgttttcatg ctcgacttca tggattttcc cgtggccgaa tagaaaaacc tcggaaacag
    38581 gacggcctgc cggattgggt ttcagggagg gaggcccctt gtcctgtttg tcaaagtgca
    38641 ggacggtctt tgctttgccg cttgcctcgt caaagacggt ttccttgacc gggacgcgct
    38701 tcttggggat ggcggcgcgg gccttatcca gcttatcggc ccgtttgtcc gattttcgga
    38761 tatagggctg taaatccggg tcggcccgtt cttcctccga cagttggagc cgggcggatg
    38821 gccggtgcag ggcagcgtcc ccctcggcgg ccacagcccc ggcctgcttc gcggctttct
    38881 tggccttatg gccgtcatgg atggcgtcgg cccgttccag cagcttatcg gcggtgccgc
    38941 ccggccccgg cgcggacaaa tcctgttcgg cctcccggct ggaaatgttc tccacctcgc
    39001 cggtggcctg attttccagc gtcagcccgt cgcgggtcat ggcctgcgtc actttcgcct
    39061 tggctttcag ctctttcatg gtggttcacc tcctttgtgg cgtcgccggg tcatactccc
    39121 gccacctcgt ttaagcgggt cgtcataatc ttgtaaagct gggtgttgtg cgggatgggg
    39181 ttggtaaagg gcagcaccac gttttcaaag atcaaaaggc cctcgccggg ttcggaattg
    39241 tcgatgtact tctgctgttc ggtggacaaa ttcaagcgtt ccgcaaggat ttttctatcc
    39301 ccggacgcct gattgagcag cgtaatgaag tcgctgtttt caaggatatt ttcaatttcc
    39361 ggggaggaaa gcaggtcttt gacgttctgg gtggcacctg ttggaatgcc gccccatttc
    39421 ctaaaccgct tccaaatctc cgcagaatag gccgccgtct gttcctcttt caaaagcaaa
    39481 tggaactcgt cggcaaaata ccatgtggcc tttccttggc ttcggttggc cgtgacgcgc
    39541 ccccatatct ggtcttggac aatgagcatc cccagctttt tgagctgctt gcccagctcc
    39601 ttaatgtcaa aggacacaag ccggttgccg atgtccacgt tggtacggtg gttaaatacg
    39661 ttcagggagc cggacacata caggtcaagg gcctgcgcca cccggtcagc ctccgggaca
    39721 tgctgatcta acaacgcttt gtggaggtcg gacaggatcg gcatattctc cgggcggggg
    39781 tctgccagat agggccggta gatcacgcgc acagcccggt ctatcacggt cttttcaatg
    39841 gcttccagcc cgttcttgcc gcccatgaca agctcacaga acgacagcac aaagtcggat
    39901 ttcagggcca gcgggttatc gtcctccgaa taattcaggt tgatgtccag cgggttcaca
    39961 aagtccttgc tggtaggcga cagccggatt acctgtccgt ggagccgttt gacaaggggg
    40021 taatattcgg cctccgggtc tgaaataaaa atatcgtcag gcgtcgttaa gaacacactg
    40081 acgatctcgg atttacagct catggatttg ccgctgccgg gggtgccgag cttcaaggca
    40141 ttggggcaac gggcctgctt cctgtccagc ataatcatgt tgcgggactt ggcgttgatg
    40201 ccgtaataca tggccgcgcc gccctgaaaa agctcctgcg tcacaaaggg gacgaacacg
    40261 gccacgctgg aagtcgtaag gctgcgctgt atcttgatct gattgacgcc cagcggcagg
    40321 ctgcttgcaa ggccctgttc ctgctggtag tccagccgga caaggggaca gttatgcttt
    40381 tgggccacgc ctgcggcttg gaacacgtcg ttattcagct tttgcttggt gtcggccacg
    40441 ttgaggacaa ggaacgtcaa ctggaacagc cgttcattgc gggtctgcaa ctttgtcagc
    40501 agcttcttgg cgtcctcgcc gtaggtggca aggtcgctgg gaagaatgtc catatcgtaa
    40561 ccgctgcgga cggccttttt ctgctccgca atcttcatag cgtcaaggtc ggtaattttg
    40621 cgcttgatgg tcttgatcgc cttggtctgt tcaatggcct gcacatggag attgactaaa
    40681 acaccgcttt ccgtattgag gaagtcggcc agcatatcgt ccgacagctc cggggacagg
    40741 atttgcagga aacttaccgc gccgtatttg ccgcccatgc cgaatgtctt tgcattgccg
    40801 aagcacaggg aggacggggc aataaaatcc ttggtggaga ggccggacgg ggccagccac
    40861 ttccagtcaa aattgaatat ctcgccgtcc gggtggtaca cgccatgcag caggttcagc
    40921 cgttcccagc cgtccatcac atgggctacg gcccccatgc tcttgaaata gcctaacagg
    40981 tcaaagccga tgcgcttcaa tctggctcgc gccgctttca cgctttcggc ctcgatggtg
    41041 aatgtcaggt atttggtctt taccatgccg ttgttgccgt ttgcaagctg cttttgcaga
    41101 atgccggtgt actcggcccg gatgtcgtcg aagtcgtccc cctgcggcgc gatctcaaag
    41161 ctcttggcgt actgcaccgg gtcaactttc cgattgagga aagaaaactg gatatgaatg
    41221 gaggcgtcca catagttata caggtcgcac agtttttcaa agatagccgt ctgcgtgtcc
    41281 ggctgggcaa gctgatagct gatgtccgca aactcaatgc acttggaaaa gacgccgggc
    41341 gatacccggc acacgccgtc cgggtacatg acctcgtagg ggatgctctg ctgcgccgtg
    41401 tggggcctgc cgtcgccctt atatttacgg attaccgcgt caatttcttt tcgctgggcg
    41461 cgggtcagct ttgttttttc ggtttctctt gggatttcct ttttggacaa tggcctttac
    41521 ctcctgttcc atctggtatt gccgcacaag ggcggtgtag gtgttgtcgg tctgataggg
    41581 acgctccttt ggctggatga agcagcactg gatgatctgc ataatcacca cttcaagggg
    41641 ctggccgtga cgctcgtaca tggcaagcaa aaagcccggc agcatggcaa ataccatgag
    41701 cagggccgcc gcgctgttgg taagatagtc acgggtgaga aaatataagg ggacgccgat
    41761 caccagcgcc ccggaaaaac agatcagttg ccgtttggta agcccaaaca caaccttgct
    41821 tttcacatgg gttaagtcct tggggacggt tacataagcc atttggcacc tcctttcacg
    41881 tcaggataag gtcacattcc acctcgttcc cccacacgtc ccagccgggg gttttctgtc
    41941 tggcaaacag ctccacgcgg ggcaaatcgc ccgccagctc tacgattttt tcacgggtca
    42001 catccggctt tttgctgtgt tgttcaatcg ggctgataat aaactgatgg acagaggcag
    42061 aacgacgctt cggcttgccg tgtgttgcca gcaggcagat ttccgcgttt ccccttgtcc
    42121 agcggcccag cccgtaaaac catgtaaggc ttttacggtt ctgtttcagc catacaaaag
    42181 ccacggtctt gaatgaaaag ccccacgctt tgattaaccg cagagcttcc ggcagcatgg
    42241 ggaatgtggc ccacaaaaac agcaggcagt ctttggacgc cagccgttcc accggcaggg
    42301 cgcacagctc gtcaatgctc atggtggaat agtgattttc cgctgcgccc tgtacgtttt
    42361 tgcagtcata ccgccacggc gggtcagcgt aaatgatgtt gtacgttgaa ataagcaagt
    42421 tcctcctgtg tatgcttgga ttttgggatc aatgcgcccc gaatacggcc tttgatatac
    42481 tgccggtctt gaacaggcag aagcacagca gcaccgtata gcccatacag ccccagattg
    42541 cgccggatat gtcggaagcg gaaccgatat tctgtatcag caccgcgtag atacccacca
    42601 caaccatgat taaaaaggct tggaagccca gcgccagcag ggatttcaga tacccttggc
    42661 ccatgccgcg ccattccgcg ttgcccattg tggcaagggg gataggcccc agcgacgtga
    42721 caacatagat ttccaccatg cggccatagg tcacaaggaa aatgcagatg gaaaggatat
    42781 tcatggtgag gcccacaaca agggtttgga accacagccc caaaagagcg cccacgctca
    42841 tagcctccaa ttggctttca aggtctggta tcagggtgtt aaaatcaatg gatgtctgcc
    42901 cgataatcac accggcgctt tgattgacga cgctttgggt ggcgtcgaat acgcccatga
    42961 cgatgttcca tgtgttcgtt acgatcagga ttgcaaacgc ggatttgaat atccagcgga
    43021 agaacatgga gctgtcaaag tcgtgcatat tgttcttttc cgttatcatc tggataagct
    43081 catagcacat gacaagggcg agtatggccc cggctatggg gacgatcacg gtttccgaca
    43141 ggctgtgcag catattgaaa ataccgctgt tccatgcctg cggggttcgt cccacgtcgg
    43201 cggcgatttc tccgactttg gcatttaccg tatcgaacag cccggacagg ttgcccgtga
    43261 taccgtccat gaggatgcct tttatccatt cttcaatgat ttcactaatc acgggtagca
    43321 cctcctttcc cgcgccctcc cggtctggcc gggaggacgc ggaggcgatt agttaagggt
    43381 ttggacaggg acaaaggcca ggatcagccc agcagcccgg acagcagggg aaccagagtg
    43441 acaccgatca gggccacgcc gccgccagcg acaagctgct tgacaccctg cgattttgcc
    43501 cccggattgt cctgcccgta tccctccaac agattgatgc cgccccatac gcacagagcg
    43561 ccgcccagtc cgatcacgat agtctgcaaa gtagtaactg cggaattaaa aaatgccata
    43621 aatttacctc tttctgccgg tttccggctc ataatgattt tttgattttg ttgttggaat
    43681 gaaaaaagcc gctgtttatt cagcggcggc gtcctcgtcc gacaggtcga tttcatacag
    43741 gtcgaatact tcatcctgcg ttaccacttg ctgccgtttc cggcgcgtga tagtcaaaaa
    43801 tctgtccacg tcaaaggtat tcttcttgtc ggcgtcggca aggtatttgt accggggatg
    43861 cttggtaata tcgaatttct ccgataaaaa cgggcgcaca ccccgtagct gcaagataca
    43921 cttgccgccg tccatcacgg caatttcgtc ttgggacatc aactcctttc ctaatttttg
    43981 atagttcaat ccgtgggacg tttggcttcc ccggttctcg ctggtgttga aactgtcaat
    44041 cgtttctttc cccagcgcat cggaaatctc cttggcattt ttgccgcgcc cactaaggaa
    44101 aagcacacta tcgcagttat ccgaaatgat ctcggcggcg tccttgtaaa tcgcttttag
    44161 ctgcgactgg ctctgcaaaa taatagaggc cgatatttca cggcttcgaa tggtggcaat
    44221 gagtttatcg aaattgggta tttggccaat gttggcaaat tcatccaaaa tcaggcgtac
    44281 atggacaggc agccgcccgc cgtacacatc atcagcccgg tcacaaagca ggttgattag
    44341 ctggctttgg agcatagcca gaatgaaatt aaaggtcgtg tccgtatcgc tcataatgag
    44401 atacagcacc gtcttttcgt ccccgatggt gtccagctcc atttcgtcgt cctccatcag
    44461 ctcgcgtacc tcccggatgt caaagggcgc aagtctggca ccgcatgaaa tcaggatgga
    44521 agaacgggtc ttgcctgcgg acagcaggaa tttcttgtac tggcgcaccg caaaatggtc
    44581 ggggtctttc tgctccaaac gctcaaacat gagatcgacg gggctttgaa actccgggtc
    44641 gtcctcgcgg gcttcactgg cgtttatcat ttccagcagc gttgagaagt tcatttcctc
    44701 cgctggggcc tcgtaccaga tatagccgat cagggccgaa taaaacaacc gttccgactt
    44761 cacccaaaaa tcctccgctg acttttcccc ctcgcccttg gtgttggaaa tcagggtatt
    44821 taccagcttt agcacgtcct tttccgaatg gatgtagaca aaggggttgt acttcatgga
    44881 cttggaaaag ttaatggtat tcaggatttt aatgcggtag cccgcctgct ggaacatcct
    44941 gccggtttcc agaaccaaag tgcctttcgg atctgtcacc acaaacgaag tcggatagtc
    45001 cgtggtcgga aagcattgca tcaggttggg tttcacgaaa aatctcgttt tccctgaacc
    45061 gctgccaccg atcaccagca cgtttttatt ccgcgctgtc ttggggtctt tgggcctgcc
    45121 ggtcatggta agccgttccg tttgggtgag caggatatta ttttcaaact tggggtcgat
    45181 gtaaggcgct atgtctttgg ccgtccccca gcgggcgctg ccatactcca tgcctttgcg
    45241 gtatttcttc acgttcttgc tcttgcagta caccaccagc cgcacgatca cggcaccggc
    45301 gataccgata cacaggtcaa acaggtgcag gcttggcagc gggttggcaa aagccgccgc
    45361 aaaaccatcc gcaaaatgca ggagcttccc cgacaggtca gcaccagcgg ccagccggta
    45421 cgcctccccg catttcgcaa acaggtacac aaaaatcaga tacgggaggt tcaggatcag
    45481 caatttcttt acgtcaggct tcacagttcc agcccccttt ccttgatttt ctccttggcc
    45541 cgctgcttgg tctgggccgc cgccttttgc ttcacagcgg acaaaacctt gcggatagag
    45601 ggccgctgct ccttggaaag cgtcttggcg gtaaactccc gaaacgccag atcaaggtta
    45661 tctgcatcct tggccttgaa aatcacaacg tagtggggcg gctgggtggt cttatctttt
    45721 cgtaaggtaa aatccacgcc gtatttcttg gcgcatggct tgaacgctcc aatgttggcc
    45781 tcggtgatct caatgttgga gagatcagcc ccatgctttt taagctgctt taggctctgc
    45841 tggccgtggt gcagcgtgtt tttgcccttg gcccggtgtt gcaggtactt tttcagcgcc
    45901 gcttgcagca cttgagccgt gagcttgccc gttttcatgg acagggcaat ggtcttttga
    45961 gtaacttctt cctgcaatcg catccctcct tgtcagaaag tcaaaagcgg cgtctaaggc
    46021 ggaaccacca gacgccgcag gtagatatag gtcaaatccg cacccgcagg ccggaaaggt
    46081 cgtcggcccg gatgccgaca agataccagt tttcggccat ttcaatgcgg gtgggcctcc
    46141 atttgccgcc gatcatcacg tcgaaacact ccccgcaatg caggccgccg taatagtcgg
    46201 ccagatcaaa gcggatgtcg taacggtctg ttcgctcgtc aaaaatcaat gcgccctgct
    46261 tcatagggtc gtcctccttt tctcgttaca ggctttcgcc ctcgccgcag gaatagtccg
    46321 gcaggccgga tttaggcttt ccccaatcgg gctgtgccat gtcgtgcgcg acaagggccg
    46381 tgtagtagtt ggaaatggtg ctgggggcgt tgaacagcat agcccgcagg tattgtttga
    46441 tattgcggac tttcgttgtg ttctcccgca gacagtcaag gacaaagcgg atatgttcgc
    46501 cggtcagctt catgtacttg gatttcacca gctcggcagg gtagtcgtcc ccggcgacac
    46561 ggattgtctt tcgggcggtg cagacggttt ccagcatcag gtctacgatt tcgtcaagct
    46621 gttcacggtc aatgctcctg tcctgaatga gataggcata ctcgatgttc tccaaaatga
    46681 tttcccgata aatccgtaca gcctcatcct ttcctgtcct tttccgttcc ggcggcgtag
    46741 ccgctgcctc gccctccata ggggcagggg tcggggatgg gataggaatg gaatgggtac
    46801 tttgtccatc tgtaattatt ttttcttttt ttgataagtc agttctttgt acttctttat
    46861 ttaattgcgt tggattttcc gacgccggat tatccgatgt cggattttcc aacaccgggt
    46921 tatccgatgt tggattttcc aataccgggt tttccaatac cggctgttcg tagatggtat
    46981 agaccatatc ggccattttg ccttttgcgt cacggccctg ctcacgccgg atatatccag
    47041 ctttttcaag ctcccatacc gctgtcctga tcgcgtcgat gctttcccgg ttgatatagg
    47101 acagtccttt tagggtatag tcccaatcct ccggcaagga caacatctgc gacagcaggc
    47161 ccttggcctt taaggtcagg ttcttattcc gcaggtggtg atttgacatc accgtatagc
    47221 ctttgttctt ttccacacgg aaaactgcca tagcgttgtt cgctcctttc actgtgaatt
    47281 tgaccgctgc atagtcggtc agcttgcccg gctgataggg acactctgca aactggcaga
    47341 attgatattt ccaatccggg cggtaaaatc ggcaggtgcc gcaatcctcc ggcgcgtccg
    47401 ccccgccgcc gtcgtagtga tcgaaaccgg gcttttcctg catcagccgt tcaaacgccc
    47461 ggtcagggcc ggaagtaaat agcatggcgt cgcctccttt ctctatttgg gcataaaaaa
    47521 gcggcgtcct gttctcccat gacgggaaag aggaacgccg cgtttacggt gtcgtattca
    47581 atttatgatg tgccgtattt ggggtggcgg gtattagcag tatggttcag catatatgcg
    47641 gctcaatccg aaagtagtaa attggtagta aattgagttc tcatatcctg cgaaatgccc
    47701 gtatttccgg ggctttcagc gataacctaa atttttggaa taaaactttc attataggct
    47761 actgcaacat ccatccaatc agcaatctct ttttggatct caggtcgttt ccagtagcca
    47821 acgacgattt tattttgttt atttaatcga gcattgatga acccatattc gcggtcacca
    47881 tgagcggatt gatttaaatt catgaaatcc atatcgatcg ttttccaagg aatgctttcg
    47941 ttatattgcg tagctaaatg aagcaatggt ttttgtagaa gctttgtccc gcggatccac
    48001 atttttgctg gtgagaaagt atgcatccaa gtgatcacac ctgctacttc ttctcgataa
    48061 ttgacctctt tcatgatttt tgtgatcgta tcagcagtaa ctgctaattc ttgaaggcgg
    48121 attggataag gcaattggcc attttcattc agttcatcga ccatttcttg tgcatgtttc
    48181 tttacttctc gcagtgcttc ttccccatat aaatgctgtg atcctacaac aaaccaaaat
    48241 tctttttctc caatattcaa cataattagc cactcctttt atttgttttg tccgtaatac
    48301 gcattttttc cgtgttttcg taaataatgt ttatctaaaa tccgttgagg cagctcttct
    48361 gaaaatgaat tgagctgtct ggtaaataaa ttcatcttgc atacttcatc tagtacgact
    48421 gcgttcatta ccgcactttg cgcatctttc ccccaagtaa atggaccgtg tccgtgtaaa
    48481 agtacccctg gaattgctaa gggatcaatt ttgcgttctt tgaatgtttc tatgataact
    48541 tttcctgttt catattcgta cccgctgtcg atttcctgtt gtgtcaaaaa tcgagcacaa
    48601 ggtaccgatc cataaaaagt atctgcatgc gtcgtcccca tcgcaggaac atccaatcct
    48661 gcttgtgccc agatcgtcgc ccatgtcgag tgagtatgga cgattcctcc gatttgagga
    48721 aatgaacgat ataaaacagc atgagtaggc gtatccgaag agggattgag tttaccttca
    48781 atgatatgat tgtccaagtc cacaacgacc atgtcgtctg ctgtcatctc ttcataactg
    48841 actccgctag gtttgataac gaaatatcgt gtttcaggat caaaagcgct cacatttccc
    48901 catgtatatt tgacgagtcc gtgtttaggc aagtcaagat ttgcttggta tacttcttct
    48961 ttcagttgtt ccagcatttt ctatcactcc tttttcttgc aattgatgaa tcgctgtttt
    49021 ttcaatgtcg atcccctcac ggtaacgtct cataaatatc tgatagcctg ctatttcttc
    49081 tgctgaaggt gtgatggtga ttccttggtc ttgtccaaac acgtcttctg ccaagaagtt
    49141 ttctaaagac ttcccatgtc gatccatcat ataggctgct aataacgcga ttccccacgc
    49201 tccaccttct ccggctgtgt ccatcactgt aactggtgcc tccatagcag atgctagaat
    49261 ccgctgtcca acttctggtg ttttaaaaat ccccccatgc cccactaaac gatcaatttg
    49321 gacattctca gatttcaata tatccattcc gattctcatt gcaccaaaag cactggctaa
    49381 atggatccgc atgaaattcg ctaaatcaaa acggctacct ggtgtacgta caaataatgg
    49441 ccttccttca tttactcctg taatgttttc accggaaaaa taaccataag aaagtaatcc
    49501 cccgcaatcc gtatcgcctt ctagcgcttt gttgaataat accgtgaata atttatctct
    49561 gcttatctcc atacccaaag aattggtaaa ttcttcaaaa atactgaccc aagcattgat
    49621 atccgaagag cagttattcg tatgaaccat gcctactagt tctcctgaag gtgtagtgac
    49681 catgtcgatt tccggatgga cattttctag ttctttttct aatacgatca tagcgaaggc
    49741 ggaagtacca gccgaaatgt tccctgtccg tttggctaca ctgttcgtag cgaccatacc
    49801 ggttcctgca tccccttctg gcggacaaac cgggattcct ggtctcaaat ttcccgtagg
    49861 gtcgatcaga taagcccctg attcgcttaa cttgccagct tcttctcctg ctactagaac
    49921 tttaggcaaa atgtgatcca agtcaatcgc tacgtgcgct ttttcgatta actgaccaaa
    49981 aatatttttc atttcttgat ggtaggtttt cgttgaagga tcgataggaa acatgcctga
    50041 tgcatctcct acgcctagta ctttctcacc agtaagctgc caatggacat aacctgcaag
    50101 cgttgtcaaa aaattaattt ctttcacatg ttcttcttta ttcaaaatag attgatacaa
    50161 atgagcgata ctccatctct gcggaatatt gtattgaaat ttttccgtta atattcgttc
    50221 tgcttcttca gtgattgtat ttcgccaagt acgaaatggt actagtaact gttccttgct
    50281 atcaaatgct agataaccgt gcatcattgc actgaaccca atcgacccga ttgtcgtaag
    50341 attctcgcca tagatttcga atacttctgc tgccattttt cggtaactga cgcgcagtcc
    50401 tttccaaata tcttctaatg aataggtcca gataccattt tctagtttgt tttcccactc
    50461 ataactacca gcggcaatag gagtaaaaga tgaatcaatc aatacagctt tgatcctagt
    50521 tgatccaaac tcaatcccta aagatgtacg accatctatg acatctaaca tactttgcgc
    50581 atttacttcc ttcataatga tttaactccc tccttctcgt caaacctgat caaaccgtct
    50641 ttttagtagc gcttacaatg attattgtat acttttgtac gtacatgtca agcggttatt
    50701 tacaagaata caataaaaaa cacttgtttt gtacgtacat aagttataaa atgaaattgc
    50761 ttacaaaatc tgatcaaccg ccttctcgaa attctagaag gagagaatac ttatgaaaaa
    50821 agaaaaaaaa gtttcctcat cgtttattta tttttttggc gcatttggcg gcattctatt
    50881 tggatatgat attggtgtta tgaccggcgc cttacctttt ttacagcatg attggggttt
    50941 ggcaggtaaa gcttctttga taggatggat cacgtcttcg gtcatgttag gtgcgatcct
    51001 tggcggctct ttatctggtc ttctttctga taagcttgga cgacgaaaaa tgattcttct
    51061 ttctgcactt atttttatgg ctggttctgt cctttctgca tctgcccctc acaatggttc
    51121 ttattttctg attgcagcaa ggattcttct aggtttagct gttggcgctg catctgccct
    51181 agttcctgct tatatgtctg aaatggctcc tgctagacta aggggaagat tgtcagggat
    51241 caatcaagtg atgattgctt ctggcatgct cctttcctat gttgcagatt atttgctaaa
    51301 agtgttgcct gaaacgatgg cttggcgcgt gatgttaggg ctcgctgctg tccccgcgct
    51361 gattttattt ttcggtgttt tagctctacc agagtcaccg cgttttctta tgcaatctgg
    51421 ccgcttggaa gaggcaaaaa gagtattgaa ctatattcgg acaccaaaag aagctgaaca
    51481 ggaattcgaa caaatccagc tgaatgtcaa acaagaaaag acaaccggaa cttcttggca
    51541 tactttgttt ttagaaaaat atcgttcctt agtcattgcc ggtattggtg tagcagtatt
    51601 ccagcaattt caaggagcta atgctatttt ttactatatt ccgctgatcg tagaaaaagc
    51661 gactgggcat gcagcgagcg atgcattgat gtggccgatc atccaaggaa tcattttagt
    51721 tgctggttct ttgctctttt tggttattgc agacaagttc aatcggcgaa ctttattgaa
    51781 aataggcggt agcgtgatgg gactttcatt catcctacca gctgttttag gaactgtact
    51841 ggatgctcat acaaattcgt tgttgattct cttgttttta tgtatttatg tcgcatttta
    51901 ttcttgcaca tgggctccac tgacatgggt aatcataggc gaaatattcc cactagctgt
    51961 ccgcgggcga gcatctggcc tagcctcttc ttttaattgg attggttctt tcctagttgg
    52021 cttgcttttt cctgtgatga ctgcttctat gtctcaagaa atcgttttcg gcatttttgg
    52081 gatcatctgc tttttagggg ttttatttat tcaagagatc gtaccagaaa ctcgtgggaa
    52141 atctttagag gaaatcgaac aaagtgcatc taaaaaaact tatcctaaac gtatttctat
    52201 ccatcattct taaagaggtt gtgacagaag tggtcagctt caagaaataa gaaggaaccg
    52261 cttagtttcc agtcacaagg aacaatttca aaaaacagct tctcatgttt gatgaatatt
    52321 gtgacttgtg accagttggt aggagaacac cgtttagtgg agaggtggtg aaagaaacgt
    52381 tcagccttga gcgatgacaa aagctctcac aaacattgcg acgagtaacc gtaggagcaa
    52441 taagaggcgg taaaaacccg tctcttattt ttcgttttct ttcactgttt cccgttcaac
    52501 tagtacaggt tcatagagaa tatttggctg tgcctgtcct ttttcaatcg ttgtgacgat
    52561 ccaccgtgcg gcatcttgtc ccaacttttc ttttggatgc gtcaatgttg tcaatttttt
    52621 attccctaaa tggcttaaag aagaatcgtc tgttcctacg atcgataggt catctggaat
    52681 atgatagcca ttttctgtca acttatctag cattaaacta gctatttgat cgttatagca
    52741 aatgatgcca tctaaagctt gttcttcttt caaccgttgt actgtttttt cagcgattgt
    52801 ttctcgtgtt tccgtggtga aagtaatgat atcttccgtc aaaaaacgca cattatactg
    52861 ttcacacgcg ctgataaaac ctttcatcct gtattttcct tgaagatcgt cgatttttgt
    52921 gatgaacaac agacgctgat gtcctttttt tatcaaatat tctgctgcca taaaaccgac
    52981 tttcacatca tctaaacaaa tataagaggc atttaactct tcataagcag cattgatcat
    53041 caccatcgga atgccttgtt ctctcaaagc aacataaagt gctaagtttg ggttatactg
    53101 attacttttc gtaggctcaa cgatcaaacc atctacccca taagcaatca ttttcttcaa
    53161 acactctttc tccaattcgt gatcgttatt cgtactggct aaaagcaatg aatacccaga
    53221 ttctcgtaat tcattttcga ttcctcggat aatcgacgga aaaatataat cagagagata
    53281 tgtggtgatg acaccgatcg tttttgttct gttcaatggt gttttttctt tcttatagct
    53341 gtcatctaca tatgtgcccg accctttttc tttacgcaga tagccctcat ttaccaacac
    53401 agcgattgct tgccgaatcg tatgtctgct gacgtcatat atttcttgca gcttgaattc
    53461 tgagggaatg gttgtattta cttcgtattc ctcacgaagg atcttttgtt ttatctcttc
    53521 tgcaatatct tgatattttg ccatttgcct tgcccctttt tatttgtacg tacatatatc
    53581 ataacgagtc tgcaaggttt attcaagcaa aaatcaaggt ttcttgtgct cataaggcat
    53641 acggaacagg ttcaccaaat tctggaaatc cttgctcatt ccacgtaaag cattgcgcgt
    53701 tcgcgtgccg attaggattg tctaacggat cccctttttg gttcttctct ggtcgagcat
    53761 gatagatcaa aatatcaaag cacccgtctt ctgaaaccgt aaacgagttg tgaccaggac
    53821 caaattgctt atttttttca gaagaaacga atactggctc cgataattta tgccatgatt
    53881 cttttaataa aagattcttg tgctcatcag cccacagcag gcccatggca tagttttcat
    53941 ctgttgcact accagaatac gtaatgaata ttttcccatt gcgagtaagg actgctggac
    54001 cttcatttac tgaaaaaccc cgtttttccc attcatactc aggtatagaa aggaggatct
    54061 gcttcccctt taacgtccaa ggattatcca tttcggatag ataaagatta gaattcccag
    54121 taatttcagg atcttgttgg gcccacacat aatatagctt tccttgagaa gagaaagttg
    54181 ttccgtctaa actgaaagtt tcccttttcg tttttatttg tcccttttct atccaatctg
    54241 tattcattgg atctatatgc tgattttcaa gtacgaacat gcggtgatga tgagattcat
    54301 cacgtatagt tttatgattg cttgcagcaa agtaaatata ccattttcca ttgatataat
    54361 ggacttcagg tgcccagatc aattcactca tcggtccttc ttcatgagcc tgccatacaa
    54421 tcaggcttgc agcatgttct aattcattca gtgactttgc ccttcttaat tcaatcactt
    54481 ggtagcctgg aaccgatcct gtaaaataat aataaccatc tgtatgttta tatacccaag
    54541 gatctgcccg ttgccgaacg ataggattat tataaagtgt cttcatcata acaaatttcc
    54601 tcacattttc tttattctaa ttacattcca agagtatttt tctatcccta catttaattc
    54661 gtcatgtttt tctattgaaa aatagtttat ttcaggtttt attttttctg gttcttcacg
    54721 tgtatttttg tccaacagat cgctactggt taatgtgtag tgctctcctt gatctagcaa
    54781 attgaaatca tgttcaatcg ttatcttttg ttgttcattt gtgcgattga tcaagaaaat
    54841 agtcagctga ttgccgttat ctacgatcac actgtccaca taaggaacat tttttatctt
    54901 ttcacaatca taaacagggc aaatgatttg ttgtttcaat acttgacctt tagcatattt
    54961 cgataagtgt tgcatcacat aataagttgg attcctccat gcttgtcctt tagcatctgt
    55021 cagtattaaa ggtattgtgt ttactaacaa tgattgacaa ctaatcttta cgcgatctgc
    55081 gtgtcgtaaa atagccagcc ctaatgaacc aaataataat gtatcttcca tagtaaagta
    55141 acaccaatcg atgggactac cgacttcaaa atccctatgt cttttttccg gttgggcatg
    55201 tacattccat tcatcaaacg ctagatacat tgttttctca cttctcaaat atccttttac
    55261 ataatcacaa gtagcaacga tttcttcaat ttgacgatcg aatcgataag cttttgcaag
    55321 gtatgtcgct gtatcatcac gctcattttt aggaggttta gtcaagtctt cttcatcata
    55381 cttatcaata tagttatgca aagctaaata atctacattc tcataagctt cttctaatgc
    55441 gatacgatcc cattcagggt acgatggtaa acgtggcgta gagcttccaa ctaagattgt
    55501 ttcaattgaa tcatccacta acttcatgac ttttgaggct tcatttgcta acctaccata
    55561 ttcataagca ctcttagccc ccacttgcca tggaccgtct agctcattcc ctaaacacca
    55621 taatttaacg ccaaaaggct ttttttgccc attttttatt cttaaatcac tccagaaggt
    55681 tccttttgga aaattacaat attctactaa attttttgct tcatcaattc cttttgttcc
    55741 taaattcacc gtgaatatcg gtttcgcttg tacatgactg atccatttaa aaaattcgtg
    55801 gagtccaaaa gaatttggtt ctatacctcg ccatgctaaa tcaatttttt ttggtcgttg
    55861 ttctttccta cctacagtat ccacccaatc ataaccagat gtaaagtttc ctccaggata
    55921 gcgaatgaca cctaattcta attcctttac ataagagagg acatcttgtc taaacccgtc
    55981 accatcagct gtttcatggc ccggttcata aatccctgta tagacgacac ttcccatatg
    56041 ctcaacaaat gagccaaaca gccgagaact gatctctcct accgtaaaat cctctctgat
    56101 ttttactttc acttcttcgt ccaacagctt tccctacctt tcatttccta tagtcaagat
    56161 aatagataca agtttccata cgccaccagc aaagataaaa ataaaaggag ggaaaagaaa
    56221 tatgagcagt acaaatccta ataacaatac gcaacaaaga atatttctca aaaaatcaaa
    56281 aaatactttc catgcacttt gttcaaaaat ttgtaaaaat gtgatatctt tgttttcaga
    56341 aatcacatat atccaggata aaagaaacat ggaataaata agtaaaacta catatccact
    56401 aattgaaagt acgattgtct gttcttctaa taattgatta acaagaaaat aaataatgat
    56461 cgttaacaga ctaaggaaca agttcttacc aaaatgttgc tttattcctt gaaagaaaaa
    56521 ataaatgata tttcctgatc cctcaccttt ccattgcgcc attacataaa aaacagcaca
    56581 tgtagcaggc acgatagtaa taacaggcaa acacacgatt acccagagaa tacctaataa
    56641 gatgtaatca gaaaccacaa tcaactgtcc ataaaattta gtctcaacta ttttcatctt
    56701 cctcactctt tcattccaga catagctgtt ccttgaacaa aatatttctg tgcaaaaata
    56761 taaaccacta gtaatggcag cattgaaata accgttccag ccattacagg tccataaaaa
    56821 gaaatgttct gccctgtaaa taaagctaac cctgctggta aagttctcat ttttgaacta
    56881 cttgtcaata tcaatggata aagcaagtca ttccaactat tcatcagcgt gaaaatccct
    56941 aatgataaaa gagtaggttt gctcaatggc aacatgattt tcaaaaaaat attaaactca
    57001 cttaatccat caatgcgtgc tgcctcttcc aaagaatctg gtaaagtaat aaaaaaggaa
    57061 cgcatcatga agataccaaa tgcagttgtc atacgaggaa tgatcaaacc tgcataagta
    57121 tcaagcatgc caagcaaatt gacttcaata aatagaggaa tcatgaagac ttggaatggg
    57181 atcatcattg tcagcaaaac gaaatagaac aaaactgatt ttcctttgaa acgcatacga
    57241 gcaaatgcat accccgcaag agaatcaaag aatacagaag tgatcactgt ccctccagca
    57301 aaaatcactg tatttttgat gtaatctaat aaagggatcg ttgtccaaac cttaatatag
    57361 ttatctaggg tatagctatc tgcaaatatt ctaggcggaa atgagataat gtctttttcg
    57421 tgtttaaaag aagaaataat cagccacaaa aaaggaaacg caataaccaa caatataact
    57481 agcatactaa tcgttcgaat gattttttta ccactaactg cttttcgact attcacagta
    57541 actgtaatcg agctttctgg tgccatacag gtttccctcc tatttcattt gtttttcttt
    57601 ccgtgacatg tacacattag tggagatagc tatagttgca acaatgataa acaaaaccga
    57661 agacagtgct gatgcatagc ccaattcata aggtgctgta aatcctcgac tgtaaatata
    57721 ttgaacagct gtttctgtct taaattgtgg gccaccagcg gttgcaacat atacttggtc
    57781 aaacacttgc atcgaaccaa tcagattcgt taaaatacaa aaacctaagg agggaacgat
    57841 ctgaggtagc gtaatgttaa aaaactgctg tcgatttgtt gcaccatcca tttgagcaga
    57901 ttcatacaaa gagggagaga ttccctgaat agcagtcaag agaatcgtca tagtaacacc
    57961 aaaattcttc caaacagtca tgatggctac cgtcggcata gcaagggttg gatcgcgaaa
    58021 aaattgaggg atcggcaagc cgacttgtga aaacaagtaa ggaatcgccc ctacattcgg
    58081 atcaagcaac atagaaaaaa taatcgcaat tgacgtcaat gaacaaataa ctggaatgta
    58141 aaatgtcgaa cgacaaaaac gattgaatct ggtattttta gataatgcta ctgctgctaa
    58201 taaaccaacg ataatttgtg ttggcgtttc gagtacggtg aaatataaag aatgaatcaa
    58261 cgaattaact gctcgttcat cactaaatat acgtgtgaaa ttttcaaaac ttacaaaatt
    58321 tcttgatgta aagaaaatat tcaaatctgt aaaactaata gcaaatgttc ctaaaagcgg
    58381 tatgacagta aataataata aaactaaaaa agatggagtt aaaaacaaat acgcagcacg
    58441 atcaggacga ttccaatatt tggtgaatcc gttcatatag tccacctcat ctttcatttt
    58501 gataaaatat acaatcttgg tttaaacgaa tctgaataag atatccgaac aatcgctgtg
    58561 atttttgcaa taacacctat ctgcaaatac taggtcgatc attcagatat ctgtatcttg
    58621 ccaacagtct atcctgtata aagttctgta ctatttttgc agtaattgat tgatggcatc
    58681 atctgcatcg ttcatgagtg tctcaggatc ttctcctgct aataattttt caatcagtgg
    58741 attgatgata tcgttattga tcgcagagat ttgggtaaaa cctggtaaat atggctctgc
    58801 atagtccatt tgtttcgata attcagatac aataggatca ttttttactt cttcatcttt
    58861 tgctactgaa tccaagtagg caggaaaacc attttcgata ctccattttt taccaatttc
    58921 agttgtattc caatatttca aaaactcata gacagcttct tttttattat tatctgtact
    58981 tgccggaatg gcatatccta cgccatctaa aatagctgtt tttttgtctg aatcactccc
    59041 ttgtggtaag gtagtcacat tataatcaat ctcgtttgct ttcaatccgt tatttaacca
    59101 tggcccattg atttcaatgg ctagttgacc agcattcatt aaattgtcca tttcggcgcc
    59161 agaaatcgat tctggaccag tcttgtctac atggatcatt ttttggatcg cttttaacgt
    59221 tttaaggttc tcaggagacg caaattcaga cttagtataa tcatcgttca ctaatttacc
    59281 gccatttgct aacatccagt tatataacgg tgcagttcca tccttattga agacaaaacc
    59341 tgatacattt ttactactat cagttaattt tggtgccatt tctgtcaatt cttcccaagt
    59401 agtaggtggt tgttcagtat ctaatccagc ttgtttaaac aaatcattat tccaatacat
    59461 atacatgcct tgtacctgca tggggacaaa atactgttta ccttctactt cacctaattc
    59521 aatagccgtt tctttaaaat cagatttatc tactccatca tattcccaga aatcgtctaa
    59581 tggttgtacc gctccgtttt ctacatactg tgcaaaatct ggataattta atgcaataaa
    59641 gtcaggtgct tttttagaag aaatcgctgt aggaagtttt tcattcaaat tggcccaagt
    59701 catgatatcc atttcaattt tgatgttttt atcatttgtt ttattaaatt cattaacgat
    59761 ttcttgcaat atttcaccat cagatgcagt aaacccattc caaaaagtca aagtcacttc
    59821 tttatcagaa tcagattctg ctgaacttcc gccaccgcaa gctcctaaaa tacctgttgc
    59881 agctaccaac aaagagccaa ttaaccattt tttacctttc attttttgtt cctccttcat
    59941 ctgataaacg acatctgacc acattccaag atagcggttt caataaacaa ttgattttcc
    60001 catcttcagc ttttacattt gttgaatgac ttggttttac ttgttcactt ttaggaagat
    60061 tagttgcttt tgtatcaaat ccactcattt cagaaaaatc aatcactccc tctaatgata
    60121 attcagacaa gtgaacagtt agattcattt cttcttctcc acggttaact gcaaatatga
    60181 caagttcttt gtcatttatt acggctatac tttctaaata cggcacttct tcaaaatctt
    60241 ccgtcgcata gtttgctgaa cgaatttgtg ggcttaacac ctctccttgt ccatacacag
    60301 cagcttgcat aaatggataa tagatcgtct gtctccaagc ttctccgttt gtttctgtcc
    60361 tgattggtgc aataacgttt accaattgag caagacaagc aatctttact ctatctgcat
    60421 gtttcaataa agtgattaat agacagccta atagtaatgc atcttcaaaa ttatagttat
    60481 cttctagtaa aggaggagca atctgccaag gcgctgcttg ctcatcttgt tccgctgaat
    60541 gataccaaat attccattca tcaaaggaca ggttgatctg cttcttacta tgtttcttcg
    60601 ccttgactgt atcgcacatc gctgtcactt cagaaatgaa ccgatccatg tctaaggaac
    60661 gtgcaagata atgagaaaga tcattttttt ggttgccata atattgatgc agagacaaat
    60721 aatctatttg atcgtacgct tgatcaagaa ctgttaactc ccaatcacca aatgtaggca
    60781 tttgccgatt cgaacttccg cataaaacca cctcaattga atcatctacg agtttcatcg
    60841 ccttagccgt ttcctctgct aaccgtccat attcttccgc tgttttatgt ccaatctgcc
    60901 aaggaccgtc catttcattc cctaaacacc atgtcttaat tccaaaaggg ctctcttgac
    60961 cattcgaacg ccttaaatca ctccaataag ttcctttagg aaaattacaa tattcgacta
    61021 aattacgagc tgcatctact ccacgagtac ccagattgac agccatattg atttcggccc
    61081 ccacatgctg acaccagtta taaaattcat gaatcccaac ttcattcgtt tcaattgtcc
    61141 gccaagctaa atccaacctt ctaggtctat ttgctatggg cccaatactg tcttcccaac
    61201 gaaatcctga cacaaaattt ccaccaggat atctaatcat gggaatgttc aattctttta
    61261 ccaagtgaat gacgtcttgg cgaaatccac ttttattagc tgatggatga tctggctgat
    61321 aaatcccttc atatactgct cgtcccatat gttcaataaa tgaactgtac aaccgcggat
    61381 caactttgcc tacacgcttg acactactaa tcaacattgt ggcttccata actgacctcc
    61441 tttaatttat acatgaataa tacacctcgt tgaaagcgtt gtcaataata taaatgttaa
    61501 acttacttat tttttatcga ttttaattaa ccaaaatatt aataatgatt aaaacaaata
    61561 atttaatata acttttatta acaaatatgt taatatataa gaaaaacctt ttaagaggtg
    61621 atatatatgc aactacaaat aaacgaagaa tccttaccgg tatatgaagc attagctagt
    61681 aaaacaagga tcaagatcat ccagctactt tccaaaaaaa agatgaatgt caaagatttg
    61741 gcaaaagaac ttggagtgag cagtgctatc acgacgatgc acgtgaaaaa gctagaggaa
    61801 gcaaacatca tcaaaacaga aaaagtagga caacaaaaaa tttcgagcct tcgtgtcgat
    61861 aaaatcgata ttagttttcc agaaaaaata ttcaatgctt ttgatacgaa agaaacatcg
    61921 atacctattg gtcactatac aaattatgca attgaaccaa catgcggttt agctacgatc
    61981 catgatttta tcgggaaagt ggatgaacca cgctatttta tggatcctcg aaggatggat
    62041 gcccgcattc tctggtttac cagcggattt gtcgagtatc aggcacctaa ttttttaaat
    62101 acagaggata cattggagat gttggaagtt tctgtggaaa tttcttctga atttcctttt
    62161 tcaaatgaca attggccttc agatatcact ttcagcctaa atggtgtgga gctaggaaca
    62221 tggacgagcc ctggagattt tgctgatatc cgcggtaaat atacgcctga ttggtatcca
    62281 gataatctta atcaatacgg cttgctgaag acgatccgaa ttaccaaaca cttgacgaat
    62341 atgaatggag aacccttgtc aaacatcacg atcaacgaca tccctaaaga gcaagacact
    62401 tggcatttgc gaatcgaagt gaaagacgat gccaaacatg tggggggctg tactttattt
    62461 ggtaaaggat tcggtaatta cgatcaggat atcaaattaa aagtttacta cagctgatat
    62521 ttttcttttc tattttataa aacaaaaaca gccaatccct atgaagggac ggctgttttt
    62581 gctttattgt tatttccaga aatcatccaa aacggaaatt ggcaaatgtc gtttatgttg
    62641 tgtcttgttc caccatgctt cgattttttc ttgtgcttga gcgggaactt cttttccttc
    62701 tagataatca tcaatttcat tatatgtgac acctagtgcg acttcatctg caatcattgg
    62761 tttcccatct tcaagatctg cagtcggaat ttttgtgtat aatttttccg gtgcattcaa
    62821 tgcttgaagc aattgtttcc cttgtcgttt gtccaaacgg aataatggca aaatgtcggc
    62881 tccaccatca ccaaatttcg tgaagaatcc agtaatgttt tctgcagcat gatctgtccc
    62941 taatacggct cctgctcttt ctccagctac ggcatattgc gtaatcatac gttgacgtgc
    63001 tttgatattt cctttgttaa aatcgctgat tcccacacct gcttcgctta atacttgtac
    63061 ttgtgcatca acagctggtt tgatatttac tcgcagacta acatcgggct ggataaagtc
    63121 aagagcagct tttgcatctt cttcatctgc ttgttcacca taaggaagac gaacagcgat
    63181 aaattgatag ttttcatctt ttgtttcttc acgcatttct tccatcgtta gttgcgccaa
    63241 acggcctgct aaagtagaat cttggccgcc gctgatacct agtacaaaag ttttaagaaa
    63301 cggatatttt ttcaaatatg ctttcataaa gtcaatactt ttacgtattt cttcttttgg
    63361 atcaattgtt ggtttgacac ctaattcatt gataatttct gtctgcaggc tcatttattc
    63421 tcctcctatg cttctgtatg aagttctgct acgctttttt tcattcgttc catgatagcc
    63481 attttatggt tccagcattc agtagacaga tcgactgggt atttttgcgg attcaagtct
    63541 cgtttatact cttcccatag tgaatctaga ttttcttttg tatattcttt gatttcgttt
    63601 agtgcaggta attcgtaaac tctttttcct tcgataaaga tatcttgtaa aactgggcga
    63661 gctgtaaagt ctcgaacagt tttattgata aacgtatgca ctggatggaa catgaagata
    63721 gcttcttctt ctcgagggtc ttcatcccat aatgtcacgt agtctccttc agatttccca
    63781 tcaaaatttc gagtgatgcg ccacacttgt tttttccctg gagtagttac tttttctgca
    63841 ttgcttgata acttgatcgt atccatcatt tttccttcat catcttcgat cgatactagc
    63901 ttgaatactg caccaagggc tggctgatca taggctgtga tcaattttgt cccaacaccc
    63961 catacatcaa ttttagcttt ttgcatcttt aaattcaaaa tcgttgcttc atccaagtca
    64021 ttcgaagcat agatttttgc ttccgtaaat ccggctgcat ctaattgttc ccgaacacgc
    64081 ttagatatat aggccatatc tccactgtcg atgcgtacgc cttggaagtt gattttgtca
    64141 cctaattctt tcgccacgcg aatcgcactt ggcacacctg atttcaacgt atcataagtg
    64201 tcgactaaga acacgcagtc tttatgggtt ttagcgtagg ccataaatgc ttcataatca
    64261 tttccataag attggactaa cgaatgagca tgggtcccgc tagctggtat cccaaatatc
    64321 ttcccagcac gtacattgct tgttgcatct gctccgccga tatatgccgc tctagttccc
    64381 cagactgctg catccagttc ttgtgcccgt ctagttccaa attccaatag tggatcttct
    64441 ccgatgacag atttgatacg agctgctttt gtcgcgatca acgtttggaa attgaccata
    64501 ttcaacagtg ctgtttctac taattggcag tgcgctaaag gcccttccac ttggatcaat
    64561 ggttcatttg caaaaactag ttctccttca cgagcagaac gaactgttgc tttaaattca
    64621 aaattttgta aatactccaa aaaaccttca ggatagactt ctaatccacg caagtaagca
    64681 atatcggaat cattgaacgt cagattctct aaataattga ctaaccgttc caatcctgca
    64741 aaaaccgcgt atccgtggtt aaaaggcatt tctcgaaagt aacattcaaa aacagcatgt
    64801 aaatcagctc gacctaattc ccagtatgtc tgcatcatat tgatttgata tagatccgta
    64861 tgcagcgtca aactgtcgtc tgggtaagta ttattcatct tgtattactc ctcttggcaa
    64921 gttttcattt cctacccatt ataacaaaaa aaattaatag gaaaagaaat cttccatttt
    64981 ttctgaaaaa gcacatgttt tacggatatt tcttgctaaa aatgaactcc atctgctaaa
    65041 actatccttt cttattggta tttaacctaa acgagaaaga atacttattt tattcaatgt
    65101 atccgagaca cgaagaaatt agcgttttct atttttctta cttgataaaa taagtagatt
    65161 ttcctactac aatcgtagcc gttaagatac cgatgattga acaaatataa ccaaatgtct
    65221 ctacaacata atcaatggca aaagtttttg aagcaataat acgtctttcc ttttttgctt
    65281 cttatcccca aagaaacgga tataacttat tatgtattga atttttttgg aaaggcgaat
    65341 tatgacaaga tataccttgc gttgaaaaaa ctcgcggaaa aaatatcaca cgtttttaaa
    65401 aagatacaaa gtaagaaagc agctgtcaat agaatggaaa caaaaatggc gagacatcaa
    65461 tcagtctcgc cttgtttttt attgtataca ttagatatgg agcaggttac cataaagatg
    65521 attattagtc gttattaaat agaatccttc gtattttttt gttctatcac tacaatatct
    65581 ttatttggac gtttgaattg tattccggca cgttctagct cctgtttcac tcctacatgg
    65641 actttgacat cttctcgtgt catttttaaa acgtgatgaa tcgcatagtc gatttcttgc
    65701 cttgtgattt ttttcttcgt attgatcatc acgacttgct ttttatcata tgtgtctacc
    65761 aatagcagtt gtgttcgatc taacgaaaat aatttgtaat aattaatagc cgtattccca
    65821 aaaaagaatt ccactacttt aggataaaat gtcttaatat ttaaattact attcacaggt
    65881 gtttcgatta gcttcatctc attcctcttt tctatatagt cgatttagat ccaatcttaa
    65941 gttatgttac catctttcct agcattaagg aatcggttac aattgaacct ttaaagacaa
    66001 aaggatttac cttttatcac ttaatagtat aacataattt catgagaaaa aaatacaatt
    66061 ttttcttgac catctcgtta cgtaaaggat tatgcttaca tttgtcagga ggaaaaataa
    66121 tggagtacac aataaagaaa atgtcagaga tatcaggagt cagtccgaga accttgcgct
    66181 tttatgatga gattggactg ctaaaaccag ctaggatcaa ttcttcaggt tatcggattt
    66241 atggcaaaaa agaagtcgat cgtctgcaac acatcttatt ttatcgaaca atggcattca
    66301 agttggatga tatccaagag gtcttagaca atccatcttt tgaccaccag aaagctttaa
    66361 tcaagcatca gcaaatgttg ctggaaaaac gggcacaaat cgataccctc ttgacaactg
    66421 tccaacagac acttgatatg tacgaaggag gaagaaaaat gagtgacaaa gaaaaatttg
    66481 aagggtttaa acaacaaaag ttgaaagaaa atgaagaatc ctatggacaa gagattcgac
    66541 aaaaatacgg aaaaaaaaag gttacagcat ccaatgaaaa atggatgaat atggataaag
    66601 aaacgtatga agaaatgcaa actgttgaaa agcagatgtt atttgatctc actctttact
    66661 taaaagaacc agaagatgaa agcttagcag accgtatctt ccaagctcat aagaagtggt
    66721 tatcttacag ctggcctgaa tatcagccaa aagcgcataa aggactagga atgatgtacg
    66781 aagccgatga acggttcact gcatattatg acgagcgaag tggtcatggt gcagcaaaag
    66841 ctttaaatga aattatccaa aaaaaggcgt aatcttttac atgatccaac aaaaaagtac
    66901 acgtaaaatg acctaataac aaaacagcag acacccaagt tagattttta tgctaacttt
    66961 tggtgtctgc tccattcttt cacaagtttt ttcatcctac tttaaatata ttcatcgttg
    67021 aataaacgta taaggtattt tcactttatc ctttttttct gtaagaaaca attgaaatgc
    67081 catttctccg caagcttcca gatggtggtc gatggttggg aaaccaagaa gctcgctgat
    67141 cagcaaatta tcgcgtccaa tcaccactgg tgtcttatct tgcagatagc tttgcaagat
    67201 gcctgctgca accatatccg aatttgtaaa gacaccatca actccaagct ctttaaaaaa
    67261 gaagcctgct tgttttcctt tctctgcatc tatacaatcc caaaaaacaa gtgattcatc
    67321 aaaagatgga aaaagttgat gacatagctg caaagtgatt tttgagttat aacttagcct
    67381 gccacttcgc cccaacgtga tgcccaattg ctttatacct tgctgcttca aataagtaag
    67441 accttctgta attgattgtt ctcgatcaat aaagacacag cttgcctgtt ttcccttgat
    67501 ttcttcacaa aaaactagag gtccatattt ttgatatgcc aataaatcat ctagtgtatt
    67561 ggcacgagac gtaatgatca atccatcgaa agctttagct gcaaattctt caagatacct
    67621 tcgctctttt tctttctgat agcccgtcgg taaaagtgtc actttgtaat cataatcaaa
    67681 cgctgcttca atgatcccac tgatcaactg atcaaaatac ggatgattgg tataaggcag
    67741 aatcactcca atgcttttcg tttttccata acttaactgt ctggcatttg cattagggat
    67801 ataatcgact tctttcatga ccgcaagtat ttctttcctt ttttcctcat ctacatatgg
    67861 atgtccattg attacacgtg aaatagtaga aactgaataa cctgtgagct ttgcgatatc
    67921 tcgaatgttt gccactgctg cttcgccacc tatacaaaaa gattttcttg taaatagtct
    67981 accacagctg gaccgcattc aaaaaactga tacatttttc cttcatgcga aaaactgatc
    68041 cgctgcccgc cccaatatat atcttttgtc aaattttcga tttcattcat tggtatttct
    68101 tttactatat tcctattcaa cccttgaaaa ctgtacaacg ttaatacgga tcccttgaac
    68161 tcgacaaacg cataaaaata attgttcgtt gtgccatctg ttatctctac ataagtattc
    68221 attgcaagcc ctccttttga tactttgagt atagtgtatg aaacgcgtct catagcaagg
    68281 agtttgtttt gccaaagaaa agttttattc ctctttcatt attaccaaag tctcttattt
    68341 taaattgaat acattataat gatactgtaa atatatcttt attattagtg aatggatatt
    68401 tacttttaat agataaaata ttataactat taaaaataac tattttcatt ataattacac
    68461 acaaaaaaga gcgtgagaca aaagtaaaga acacttttgt ctcacgctct aaacacgtat
    68521 aaacagcgga agcagaagca actccttcgg aaataagctg aaattcacaa aaatttgaaa
    68581 agcaatttcc gtgaatttct tcttatttct tggagttaaa cgcttctgtt ccagcctctt
    68641 tttatctgtc tttcactaat gatcagttgt agataagcaa gttgcttttt cttacatcat
    68701 accgcccatc attgatggat ccattgcagg agctgctggc gctgctggtt ctggtttatc
    68761 tgcaacgact gcttctgtcg ttaataacaa ggcagaaacg gaagcggcat tttgcaaggc
    68821 agaacgtgtt actttagttg ggtctacgat acctgcttca accatgttta cccattctcc
    68881 agtagcagca ttgaaaccag tgcctagttc cacgttcttc aatttatcaa caatcactga
    68941 tccttcataa ccagcgtttt cagcgatttg acgaattggt tcttctaaag cacgaacaac
    69001 gatcttgata cctgttgcca cgtctccttc tgcttctaca gcagaaactt tgctgataac
    69061 gttcactaga gctgtaccac cacctgagac cattccttct tctactgcgg cacgtgtagc
    69121 attcaatgca tcttcaatgc gtaattttaa ttctttcaat tctgtttcag tagctgcacc
    69181 aactttaaca acagctacac cacctgctaa tttagctaag cgttcttgta atttttcgcg
    69241 gtcaaaatca gaagttgttt cagcaatttg gtttttgatc aattgcacac gagcttcgat
    69301 tgcttctttt tctccagaac cttctacgat cgttgtattg tctttatcta caacaacttt
    69361 agaagcattt cctaagtttt cgattgttgc atctttcaat tctaaaccta gatcgtcagt
    69421 aattactgta ccacctgtca aaatagcgat atcttcaagc attgctttac gacgatcgcc
    69481 gaaaccagga gcttttacag ctactacgtt gaatgttcca cggattttgt tcaatacaag
    69541 agttggcaat gcttcaccat ctacatcgtc agcaataatc aacaatggac gtgattgttg
    69601 caagatttgt tctaacaatg gcagaatatc ttggatgtta gagatttttt tgtctgtgat
    69661 caagatatat gggttttcta gaacagcttc cattttgtcg ttatctgtta ccatatattg
    69721 tgataagtaa ccacgatcaa actgcatacc ttctacaaca tctagttctg tttcgatccc
    69781 ttttgattct tcgattgtga tgacaccgtc gtttccaact ttttccattg catcagcaat
    69841 caaatgtcca actttatcag aacccgaaga aacagctgct acttgtgcaa tggcttcttt
    69901 tgaatcaaca acagttgaga tattatgcaa ttcttcgact gctgcttttg ttgccaattc
    69961 gatcccgcga cgaatgccta gaggattagc acctgcagtt acgtttttta aaccttcgcg
    70021 aacgattgct tgtgtcagaa cagttgctgt cgttgtaccg tctcctgcaa tatcatttgt
    70081 ttttgatgct acttctgata caagttttgc acccatgttt tcaaaatgat cttctaattc
    70141 gatttctttt gcgatcgtca caccatcatt tgtgatcaat ggagagccgt aagatttttc
    70201 tagtacgaca tttcggcctt taggtcctaa tgttactttc actgtatctg ctaatttatc
    70261 taccccgcgt aacatagctg cgcgtgcgtc ttctgcaaat ttcaattctt ttgccatgat
    70321 tgattcacct cattgattat ttttgattat ttttttatct tccaaattta ctcaacaatc
    70381 gccatgatat cttttcctgc gacgatcaga tattcttttc cttcgtattt tacttctgta
    70441 ccggcgtatt tttcgaacat aacttggtcg cctgctttta cagcggcagg aactttttca
    70501 ccgttttcta acaaacggcc ttcaccgact gcaacaactg tcccagtttg gggtttctct
    70561 ttagcagcag aagctaaaac gattcctccg acagtttttt cttcttcttt tgcgacttcg
    70621 ataatgacgc gatcacctaa tggttttaac acgataaatc cctccgataa ctcttttttt
    70681 aatctgttag cactcttaac cttcgagtgc taacctacat ttttaataat actcattctc
    70741 cctctttttt gcaagctttt aaatcaaaga aaagaaattt tattctgaca gctgcttatt
    70801 gaaattatga tataattgaa atcaatcgat ataagcttgc cttgcatgct tgttatccct
    70861 taaaaggagg aattacatgt ctttaaaaaa atatagcttc ctcagcattt tttgctatgg
    70921 tctaattttt atctcaccct tgatcctagc ttcgatagga cttgtaaaat ctacgtctga
    70981 attgatcaca gcaactgcag tcatgtatat actaggcgcc gttgtcctag ctatttttta
    71041 ttttaagcaa cgtgaaccct tagcgatcga atcagcggta aaaaaagctt ctgctccaaa
    71101 gattgttatt tatggattgg ttggaatctt tgtcgcattg attctgcaaa gcatcgctgt
    71161 catgttagaa tctgtattgt ttggcaaagc aaccccttcc gagaatacac aaaatatcat
    71221 ccagatgatc atggaagcac ccgcttttat tttggcgaca actgttgctg gacccatcat
    71281 ggaagagttc gtattccgcc gcagtatact ggggatcatc agtcgatatt caaatttttg
    71341 ggtcggagca gtgatcagct ctttgctgtt tgcgtttgct cataatgatg gtcatctgct
    71401 aatctacttt ttcctaggtt tcttcttcag cctagagtac aaagcaactg gtcggatctg
    71461 gacatcgatg atcacacacg taggaatgaa cacattagtt gttcttgttc aattagctgt
    71521 ccaaaaaggg ctagtataaa catgactata aatactcctg tcatcctaga ttggtgattt
    71581 tcccaatcta aagcgacagg agtatttttg ttttttagtc gttcatcttt tctgctgctc
    71641 catcattttt tgtctgtctt tcctttttgc agtttgcaga atctattttt ttcaaaaatg
    71701 ggaaataaat gaaaaaacta attgacaaca cgataccttg taaaatcgct gcaggcactc
    71761 cgcctactaa gaaacccgag aggatcggcg gtgttgtcca agggacttgg actgctgtaa
    71821 ataaaggaac gaatccaaaa tataaagcgg aataggtaat caatcctgaa acgaccggtg
    71881 cgaaaataaa aggaacagcc atcatcgggt tcatcacgat cggtgtggaa aaaataattg
    71941 attcattgat gttgaaaaag gctggtaaaa gagcaagatt tcctaattct ctgtatttct
    72001 tcgatttcgc aaaaaccgtc ataaaaaata cagcccctaa cgtcaatcca gcacccgtaa
    72061 ccgtcatgaa ctgatcgaga aattgctgag taacgatatg tccgccattt gccaccgtca
    72121 actcttgtcc tgaggctaag atttctgcat ttgctaatga attcgcttgc aagacgggac
    72181 taaccaaccc attgaccatc gcagatccat gaagaccaaa taaccataaa aacggaacaa
    72241 aaaaacctaa taaaagcaca ccaaacaacg tgtctatgaa cgattgaatg ggaagctgga
    72301 catatgtcca tactccttga acaacagtca ttctgaacaa atgttgaaaa accgctgaac
    72361 cgataagcgt aaaagtgact ataacaatga ttggaatcaa tgaagtaaaa gactgccaaa
    72421 cattttcagg tatcttctct ctttgcttcc accctttcgc aagtcttact aaacgtgcat
    72481 agccccatcc gatgatgagc ccagttgtaa ctgctcctag tatcccttca gcacctgtcc
    72541 agacagtatc tatctgagta tttagtggct gaataagcag tagataagca gacaaggctg
    72601 ttatgccgac tggtaagcga tcgatgtctt cttcttttgc ataagcgtat gcaatggcaa
    72661 aaacgatcca aaaggctatc acatcaaatg tagcctggta tacttgtgta aaatacatag
    72721 aaaatcctgt tttgtctatc cactgagcga tgtaatccac aggaaaatga gcaaataaga
    72781 aaaacagcga gccaacaata attattggga tcgtgtaagt cattccatta cgcaaagcag
    72841 ttaagggtct aagattcaca acagatgtta tcattggtaa aaaggcacga tctaaccact
    72901 ctttcatttc ttatctcctt caacttctat ttttatcaat cagttttctt aatttaacta
    72961 tacccaatga tcacgaacca tgaaaggaat gcgcactgag cttttcaaaa atcggattct
    73021 ttgacgaata ttcagcaact gcttacaatg gacaggaata aaaaaggagg ttttttatga
    73081 aaattgcact cattggagct actggccatg caggttcatt tattttagac gaagcattgt
    73141 ccagagattt agacgtgacg gcaatcgtgc gtcatccaga aaaattgcca tcagatgttc
    73201 cgtttataca aaaggattta tttgagttga caactactga tcttgcatct tttgatgttg
    73261 tcgttgatgc tttcaacgct cccaaaggaa aagaagaaat gcatcaaact tctttgtccc
    73321 atttgattga gatgcttgaa ggaaccgata cacgcttaat tgtcgttggg ggtgcctctt
    73381 cgttattctt agatacagaa aagacgactc gtatgattga ccaagtacct aaaaatgcac
    73441 ccttctatcc aacagctttc aatatgtacg aaggattgtt aaaattgaaa caatctaaaa
    73501 atctacattg gacttatatc agtccagctt ctttatttga tccacatggc aaacgtacag
    73561 gtacttattt gttaagtgat gattatttac aaagaaacgc tgctagcgac agtacgatca
    73621 gcatggcaga ttacgcgatt gcattagtag atgagatact ggatgagaaa catgaaaagc
    73681 agcacatcag tgtagtcagt cgataatacg gttatttttt taatatgcta aaaaaataaa
    73741 aatagaagat aaaaccaacc ctgattgatt ttatcttctg ctttttatat ttttattgat
    73801 tgaactgttt aaatcgaaaa tagctcagtt gcttcatctg gatctgtatc atagatttca
    73861 aaatcatgtc caacgccaaa atctttttct ttcaaaacat tttccattgt taaatgagca
    73921 agttctttca tattgttttc cttgctaaga tggccaagat agattcgttt ggtccgatta
    73981 ccgatcacat cagtcatgac aagtgcaccg tcttcgttgg aaagatgtcc tctatctcct
    74041 aaaatacgct gttttaaatt ccacggataa ggtcccatgc gtaacatctc aagatcatga
    74101 ttactttcca tcaaataacc atcggcattt tcaatgacac ctcgcatata atcactgcaa
    74161 tatccggtgt ccgtcaacat gacgaatgac cgattttctt tatggaaacg ataaaattgc
    74221 ggagccgctg cgtcatggga gacgccgaaa ctctcaatat cgatatcgcc gaatgttctg
    74281 actttcccca tctcaaatag atgtttttgt tccactggta catttccaat cagtggttcc
    74341 atcgcttccc aagtctgctg attggcaaaa acatccaaat gatacttacg agccaagaca
    74401 cccacgccat gtatatgatc tcgatgttca tgcgtcacaa gtattccatc taattggtcc
    74461 ggtgtccgat caatttgagc catcaaggaa gtgatttttt taccgctaag tcctgcatcg
    74521 accaaaagcc gttttttttc actttcgata taaagtgaat tacccgaact tccacttgct
    74581 aggatactga ttttaaaagc tggtttttct tcagccattt gactcctact tcccttctta
    74641 ctttgtaaac ttttttcatt atactcgctt ttttattgat cttccacttt tggtacagta
    74701 ttgtttgtca cgatcgtatt gctgaaagcg ttgacgctct caatttggac cactttatcg
    74761 cttgtttcga tcgctacatg ccaaacagga acatacacat ttttttcccg gactttcaga
    74821 atacaggaat aagctagctg acgccataaa atttttgatc ctcttggtat tttgttattg
    74881 atgtacaatg tattgattgc ttcctcttcc gtatacagtt ccgtcttttc gcgcagctgc
    74941 tcgatatcag ataaatgcgt ctgcatgtat ttcgtgatgc tataatcatt atcgtttttt
    75001 tctaaagaaa gaacgatttt tgctgtatca tcattgaatg ggatgccttc atactcttgg
    75061 cttgcttgga tttctagtgg ttcttcttct aaatgagaaa agtttttcgt gtacacataa
    75121 tcattaccga ataaaatatt gtctttgtta gataaaaaat cttccaagga actactaatt
    75181 ttatctggat cgatcacgtt cttttcagca tctgaactgg ataaagattt cgtcaaaaca
    75241 tcaccgtcta aaaacacacc acttgccagc aagccgcttt taccagcctt gcgataattc
    75301 gctaatgaag tgctaagatt ggtctgctcc gcgctaagat aatagccttg cttgttctca
    75361 gacgaaatct tccccgtgta agtgatatcg tcgctagcca gacgttgttg gattgattca
    75421 gtctgattag agcgaatgac attgttttct tggtataccg cgtcatgata actgctgaat
    75481 aaaaacacat tcaaccctaa aaaagcgacg aaaaatatcc attcgatttt tttgaaatcc
    75541 aattaattcg cctccaatcc aggtaatttt tccagaaggt cgttagctga ataccagtta
    75601 tctttatatt tcacatacca ttcaggtaag agatcaacga cacgattcgt ttctttgaca
    75661 ttttgccatg tatagccaac gatcactgaa ccaatcttgt tgctatctgc tcccttagct
    75721 tttaactgct ggatgatttc attcgtactt gcaagttcta cttcttcgtc tgaaggtatc
    75781 ggcacttgaa tcgtattcaa actggtttgg atattcactt gcacagaacc attcgtttca
    75841 ccgccaactt ccacaccaat ctgtcctctg ctgtctgtcc caaaaaccgg gaagccttcc
    75901 acgaatatcc gataatcgat cgtattgtca ctgcggtcaa aatatctgag gttccctaaa
    75961 gaactgccta atttgctaat ataggggaaa ctttcagaaa atacactagc attttctttt
    76021 ttctctggca gctctccacg aaaatcaact acttgcgttt ccgaatggat agacattgtt
    76081 tcattcccac cgtaaaaaat caattcattg ctttcatcat tatttttcac gctatctggt
    76141 ttctggaaaa aagcatttct aaaaagtgta tagggttgct gtgacaggat ataactatac
    76201 ttcttcagtt tgatcgaatg tttcgtagca tattgcgtgt cgatcgtcga tggttctgtt
    76261 gtcatttctg tccattttgt gtcttttgct gttaattctt tattgatatc tgtccaattc
    76321 aacgaaatat ttgcttcata tacgagatgg ttcgaataat tcaaaaatcg gattttttta
    76381 tttccttgat cgaattgtat tctagtaaaa tacatatttt cgctttcttt tgccaagttc
    76441 gacacatcta aatctaaatc aaatgcttcc ttgtattctc ttagcaaaaa aggcgcatta
    76501 taggccaact caaaaccaga gttcagattt ttcacctgtt caaactgtga tttgtctcct
    76561 gaaactactt cagaaagctt tccaaatctt gctttatcga tgatcaattg caatcggtac
    76621 acgagatttt cactgttggt ttcttggatc attcccgaat ggtgccatgt aacatgaagc
    76681 ggaagaaaga cttcggaagt ttttcgattg ctttgagact cgatcatttg agtgtttgtc
    76741 tcatctacgt tgattgaact ttttcctgct gggctcagcc agattgcata agagaagtat
    76801 atgcttaacg caaccatcaa aatgagtcct atacgaacga ctttttcaga gattctcatt
    76861 cccaccattc ctcctcataa ggttcatatg gcagcgagat ataaaaagtc gacccttttc
    76921 cttccttgct ctctgcccaa atagcgcctc gatgcgcctt aatcacttct ctagaaatag
    76981 ctaatccaag tcctgtccca ccttgtgctc ttgcacgtgc tttatctact cgatagaacc
    77041 gctcgaacac tcggttcaga tcttttttag gaatccccaa tccttgatcg gtgatactta
    77101 aaatcacgtt attatgcgtt tctaataagc gacaagtaat cgttccccca tctggtgaat
    77161 acttgatcgc gttattcatg atattatcga ctacttggat gattttatct gtatctactt
    77221 cgacccaaag atctctttgc gtaaattcac gacggatctt ataatttttt tcctgatttc
    77281 ccaccatcat atcaaaccgg tcaagaacaa aattcactaa ctcgttgaaa ttgacatatt
    77341 ctaattgaag ctgggtatta cctgtatcca tgcgagatag atttaagagg tcattgatca
    77401 ttcgaatcat tcggtctgtt tcatctagcg ttaccttcaa aaaatttggt gctacttcct
    77461 cgtctttcca cgcaccttcg ctcaatgctt cgatataact acgcatactt gtcaacggtg
    77521 tacgaagttc atgggaaaca ttagagacga attcacgacg ttcccgttct gttttttctt
    77581 gttctgtcac atcatgcaag acagctacta atccgctgat aaaacctgat tcgcgacgga
    77641 tcatagaaaa gtctactcgc aagatcatct gatcactttc caatgtactg gttgaacggt
    77701 caagtaccat ttcgtttgga tcttctaata atttccgcaa cgtatattct tcttcgatat
    77761 ctaaaagtgt caaaatcgat tgtccgattg cttcctcgtt tttgatatct agcaaggaaa
    77821 cagccatatc attgatcgta atgactttac ccctgcgatc tgtcgcaatg acgccgtctg
    77881 tcatatggga tagcacgcta tccaaacgat tgcgttcagc ttccattgta tcttgagctt
    77941 cttcaatacg ttcagctaac tgattgaagg tatcagccag ctgtccaagt tcatcttgtc
    78001 catgcacttt gactttccga ctgtagtctc ctctagcgat tcgaatggct tgttctctca
    78061 tttcaccgat cggctgtgta atcgaacgag caactaaaac agatacgatc attgaaataa
    78121 atgccgcaat tagtgaggca gtaaagaaaa tgactgctgt gttattgatt tccgaatatt
    78181 tttgttcgat attacttttg acgtaaagag ccccgataac ggcatcgccg gtcggggaca
    78241 ggatcggttg aacattgata ttcacccgtt tatcgtcgtt atctaaagca acataacgtt
    78301 tagtcgtgaa atcattgata tcaacataat catttttctt tcccacagcg ctttgttcat
    78361 tgacatcggt tgttcctcgg atgatccctt tttcgtcaac gacccgtatt tcgatgatat
    78421 cgctagtcgc actgttttca ataaatcttt tgatattcgc atttacctct tcatcatctg
    78481 cattatcttt tcgattcaat tccgggctga ttgttgttgc taatgattcc accgtttgat
    78541 tcatatcttt aataaatgta ttgatcgtgg aacgttctaa accacgtata aagtaggcac
    78601 caataatttc gatcgagatc aataaaatca gaataaaggt aatagcgatc ttaaaattga
    78661 ctgatcgaaa aaagcggact tttcttttca tccaattact cctgttctgg gttacgcaaa
    78721 tagtaaccga caccacgacg tgtcactaaa taatttggat ggcttggatt atcttcgatc
    78781 ttttcacgca aacgacgtac agttacatcc actgttcgta catctccaaa ataatcataa
    78841 ccccaaaccg tttgtaataa atgttctctt gtcatcactt gtccaaggtg cttcgccaag
    78901 taaaagagta gttcgaattc acgatgtgtt aactcgattg tttctcctcg tttcgtcacc
    78961 atgtaagctt ctggatggat cgtcaaatca ccaatcgtca attccgcagg tgctgcctct
    79021 tctggttcct tcgcagccgt ggcaccgcga cgaagatttg ctttgacacg tgcaactaat
    79081 tctcggttgg aaaatggctt ggtcacgtaa tcatcggcgc ctaactctaa gcctaggact
    79141 ttatcaattt cagaatcttt ggctgttacc ataatgatcg gcatatcata agttttgcgt
    79201 acctcacgag caacttctaa gccgtccatt ttaggtagca tcaaatcaag taaaatcaaa
    79261 tcaggttcta cctcagcaac tttttccaag gcttcttccc catcatatgc agtataaacg
    79321 tcatagcctt ctttggctaa attgaatttg acgatatccg aaatcggctt ctcatcatcg
    79381 acaactaaaa cttttttcat aaagagccac ctcttatata ttattgtcat accttctcat
    79441 tataccgtat ttctgctttt gtttcatctt tgcctataaa acaaaagaga aaattaaaat
    79501 gaaagtgcaa aatactttat tattttttgt tctaacttca ataaaaaagg aaaacactga
    79561 ttttcacctc agtgtttcct ttttttgatt tatccttcta aaacttgtac accgacaccc
    79621 aataatcccg gaccagtgtg gactactaat gccggagaaa tctggccaaa gtagatttgg
    79681 tttgcttgtg ggaactctct tttaagtctc gcttccattt caattgcttc ttctttcgca
    79741 tccccatggg caacagctaa gttgaagacc tttgcattac cgattttttc tttgacgtaa
    79801 gcaaccgttt tatccaaact ttttttacgt cccctagctt ttcctactgt gtaataaatc
    79861 ccttcttcat tacatgagat gattgggtta agctttaaag cggttcctac aatagaagca
    79921 actaaaccga tccgtccacc tttttgaaga tattccaatg tcgcaacatt aaagaaaact
    79981 tttgttcttt cgactaactc attcagatta ctgatcagtt gatcccattc tactccttct
    80041 tccagccatt ttgctgcttg gatcgcagaa aaacctgcac caataccaat atttttcgta
    80101 tctagtacat atgcttccaa ttcttcttgc tgttgtgcaa ttaaacgaac cacattatat
    80161 gtcccgctca atccactgga aattgttacc gcaagtacct tttcataacc gtcttttttg
    80221 atttgctcaa agatttctgt gatcgactca ccatccggca aagatgtacc agggatttcc
    80281 tctggcaaac gttgatagat ctcttcaggg gtaatgtcaa ttttatctgt atatacctga
    80341 tctttataaa taattttcaa tgggatcata tacatctcgt atttttttat caattcttct
    80401 ggaacatccg tacctgaatc tactaaaatt gcgattttat tgtttttcat ttgttttctc
    80461 ctcttttaaa tattcggttt ctagaacaat cgttttttcc gcaagaagtt tcattgcaaa
    80521 cgataaagtt gccgctctta cagcaatata ttctacaggg gttgcctggt cgaatttttg
    80581 cggatgagat ttaccttgtg ctaattggct gaccatccac acagctgctt cttgttcatc
    80641 gcaaaataga ttataggctt cacgaattcc tactgttttt ccttggaaca atatcccttc
    80701 tttgatttca ggaatagtca atacttgttt caacgtagtg attgcaagta aaaatgctac
    80761 gtgttctttg ttatatcttt ttttaactgg tgctggtatc aaacctagtt taacgtaatt
    80821 gtttaccata gaagaggtaa gcaatggatg cttttctcct tgtatcacag gtgaaagata
    80881 acgatcaact aacgttctga cttggtccat ataaagttct aagtcaggga gttcttccca
    80941 gtgaggcaga cggaatgttt ctagttcctt cccccactcc attaattgct gacgcatttt
    81001 ttccatcata accgctcctt ttttcatttc ataaacatga tatcagactt atgataaaca
    81061 ttcaatctag ttgctttaac taggtgattt gattagcggg attccatgaa aacaaaaaac
    81121 aagaaggcta agccttcttg tcttttatcg ttaagaacag gagacccgcc ggggagacgg
    81181 cgggaaagga gtaaaaaatg aaaaaagtgt tagggtttgt tctcttgcaa gaactttgtt
    81241 tgttggtatg cttatataat agcgagcaaa tgtgaataat ctatgaatga tttcctataa
    81301 ggaagtaaag atttttctga ttttctttaa atgtagtctt gcattttaaa attcttagtg
    81361 ctactattat taagtacttt ttgtacgggc cgttagctca gttggtagag cagctgactc
    81421 ttaatcagcg ggtcgcgggt tcgagcccct cacggcccat tgggtgccaa acccacggaa
    81481 caggtaaatg ttggtgcgaa agcatttcga aaacatttac gctgttcttt ttttattttt
    81541 caaaataact agggcttttt atttttaact caaagtccac tgtagccctt tggactttga
    81601 gttaaaaaag aagcataatt atgaacagta aagtttctaa tataacaata attcgagaag
    81661 ctttgcaaaa tcatgctgcc aatgaactct ctaaacatat aggattaaat ctaagtacta
    81721 taaaaggtta aaaagtgaag aatatttaat agaaaaacta aatttacttg ctgctttccc
    81781 cttttccatt aatacaacaa tcagagagtg tctttttttc gaaaaaatta gaataaataa
    81841 aagacacgta gtttttttat ctacatgtct tccatcgact acaagttatc atttctcaaa
    81901 acgtatttag cttttaattg attaatcgtt tcacgttgtc tacacattgc ctaattaaga
    81961 ttttcttatt agaagcatca atcccgcaat aatacctaaa actccaggaa ttacccacaa
    82021 taatgttaaa agaaaaaatg gaataataga taaaatgagt aaactaatac catagaccac
    82081 tgttttttga ttttttctta ctaaaaaacc tattatgaaa atcattatcg aaaaaactag
    82141 ggtaattcct ccaaataaaa caacattccc gcttagattg actaacatat ctatatcctt
    82201 actggttagt tctgtagtat ttaaagtagt tgaatcaata gaagatagaa acataccacc
    82261 catcaatgct aaaagactac ataaaatccc tgttattcca ctaattaaaa tcaaaataaa
    82321 ctctgttttt ctcttattca tttaattctc tccagattaa gtgttttaga attagaaatt
    82381 ttttgaccat agttaatagc ttctaatgaa cgaataacaa ccactgacgt gttagaaaaa
    82441 taatccccaa tatgttgttt cttgggcgtg aaagcagcca ccaaataccc aatttgaaat
    82501 acaaaatttt ttaatataaa cctacatata cactcacgaa taaagatagt ttgccaactt
    82561 agctcttttt cctcaaagct cactactctt atcccaaaaa tcattttccc aattgtttgt
    82621 cctgaattca gcttagtcaa aagtacaaaa taggttaaat aaatagctaa tgacgctata
    82681 ccataaaaag taataatgga tttgtcagat tccagtccca tgattttgta aaagagacct
    82741 atagtagcat gggtgatgat gctaatacaa attaaatcaa taagaaaagc aaaaaatcgt
    82801 aaccaaaatc ccgcaaatac ataattaggc aaagtttcaa tgccactctt cttattcatt
    82861 ttatagccct ccatagtaat acattggttt tggagtatca gaaaatccaa gtttttcaaa
    82921 aactgaaatt acacgatctg atgtagttgc ctttagccct tgccattcag caatcttatt
    82981 acctaaccaa gaagaagcaa agccagttgt gtcattttta tattctataa ccgtcgcatc
    83041 agttaatttc ttctcttttt ttagggaatc taatgcatct tcagagtaac caatttgatc
    83101 caccaaccca ttttctactg cttggttacc atcataaatt cttccatccg caagttcttt
    83161 cactgcatta gtatccatat ttcttccttt tgctacaaca ttgacaaaac gatcataagc
    83221 actcatcaca aattcctgta taactttatt ctcttcctct gaaggtttgt gttgaggtga
    83281 catcatatct tttaatgcac cacttttata cgtcgcatca gttacgccaa gtttttctaa
    83341 taagccagaa taatttaaac cagaaataat gacaccaatt gatccagttg ttgtttcttc
    83401 cgtagcaaat attttatctg aaccagcaga aatgtagtac cctccacttg ccgctgtatt
    83461 tttaaatgca gtatagatag gaatatctag ctttttaatt tttgccattt ctttagcaat
    83521 ctcagcactt tcatatattc ctcccccagg tgaatttact tctaataaca ctcccttaac
    83581 cgctttgtct tcttgaattt tctttagctg tgttaaaaaa ttctgatggt tatattgttc
    83641 cctactaaaa agattgcttt cacctgtatc tgcaataact ccattgacgg atagtttgac
    83701 aatcttttta tttgatgcgc cttcttctaa cgtttcttct gtgatttcgt tagatccgta
    83761 aaaaatctta tttattcctg ttagggttgt atttgatgct tcctctttat cttttcctgg
    83821 aattagcgcg acgataatgg atagtaacaa taatccgcac gctactccca cagcaatcca
    83881 tcttctttta ttcatataaa ctcctcctat attcttagta aaaataatta ttttttattt
    83941 agaaacacat cgacaatttg ttgccaatat gttttttctc ctacaattaa agacaactct
    84001 ccagttaatc cataacgaaa cggaaacgat tgagttgttt ttaacgttcc tttcactgca
    84061 taaaaaacac ctttctcagt ggcagtagaa ttttctgaaa tttcatctaa agttccgtcg
    84121 atcgtaatcg gagccccacc tttttgatcc aatttaaaat gaaccttcat cccttcttta
    84181 atataggtac tttcattcgc aggtaaaagt gctgtaaatt tcatttttga tttttcgtgg
    84241 atcggataaa tttctgcaag cactgttcct ttggctagtt ctgcttgtcc ctttgtttct
    84301 tcatttaaat gaaccgttcc agatacagga gcttttagta ttccttttga aagttgatcg
    84361 tccaaacttt tgataactga ctggttcttc tcttgttttt catttagctc tgtaactgtt
    84421 tgttttacag ttgttattgc ttgttctagc tcttgctttc ctttttccgt ttgactaatt
    84481 ctgtcattct cagaagtagt tggtttaact aatttagctt tttctgactg atactgttct
    84541 acttcttttt ttagttgctc aatttgttca tttatgcttg ctgaaattgt cagtttcact
    84601 tgattttttt gatcatcaga aacattattt agttgttctt gccaattctc atagtttgcc
    84661 atcatttctt ttgaaaaatc ttttaatgat tgattattac tccaagctac ctgtacttgt
    84721 tgccattctt gtaatttact atctgaactc tcaatttgtt tttctagttg tctttttgtc
    84781 ttttcgtata cttctaattg cttttgatca tttaattcac tttgcttcaa agcgtagcgg
    84841 agtgattctt tttctgacaa catgctcttt aattgattac tgtagccaaa actgtcatcc
    84901 gttgaaaaca aattttttcc tttacttata ctttcaataa atagctgagc catctttatt
    84961 tgttgagtaa tacgttggtt ttcttgttct atctgagcct tttcattctc tattaaagaa
    85021 caatccaatc taaccaacac atcgtcctta tgaacaaatt gattttcttt taggaagttt
    85081 tccattattt tagcttctaa tggcacttgt aacttctcta ttttttcggg gttcaattga
    85141 gccgttgtcc gaataacaac ctctttttta gcaaaggtta aaaacaatcc aataatacat
    85201 aaaaaaagaa ttacagggta taacacccaa cggtagaagc tatgatgttg tttagtatag
    85261 atactagaat gttcgaacca attattattc tgcataaatt gtttccctct cctagatttc
    85321 ccataatttt tgatagatac catcggcaaa acgaagttca tcgtgcgttc ctttttctac
    85381 caaatgccct tcatggagaa ctaaaatttg atcacatgct tttgctattg gtaaatgatg
    85441 cgcaataaaa ataatcgttt tttcttttaa attgaggaga taattcataa ttgcatgttc
    85501 taacaaggta tctaatccac tagttgcttc atctaaaatt aatatgtccg gattttttaa
    85561 taaagcccgt gctaaggcta atcgttgtcg ttgccctcct gaaagattat ttccaccttc
    85621 ttccaacaat gtctcgtaac gtaatggctg ttgattaata aattcattta gttggactat
    85681 ctcacaaact tctattattt gttcgaaact tggtgggcta tctaaaccga atataagatt
    85741 ctcaatgatt gttccactaa agaaaaatga ctcttgaggc aaatatgtca ctcgatcgcg
    85801 taatatctga aaaggaatgt ctaagtgatt aatgtttcca taatggatcg atccttctga
    85861 tgcttcataa aaacgaacaa ataactttgc aagagttgat tttccagaac cactaactcc
    85921 aactatagcc gttttactgt gcgaaggaat tgtacatgaa atttcgttca acgttggggc
    85981 cttcatgcta tacgagaatg aaacgttttt tacagtgata tcttgttgaa ataattgttc
    86041 agaaagcata tattcaaaag actggttcga tttttctgaa tcaatcgcga aaatttcatt
    86101 taaacgatta tttgcaactt gagccgtttg cattttcact tgtaaattaa taatgttttg
    86161 taaaggatct gtcaaaaata ctagtaaagc attgtatgtg ataagttgac ctagactaat
    86221 tctattatcc ataacaaaat aagaacctag ccataaaatt aatgcactgc taattaattg
    86281 aatcaaatgt ttaattcctt gttgaatatt atcaagcgta accgtacgaa atgatttttt
    86341 cattaattta acaaattcat ggtctatacg gttatatact ttctcttcac cgctatatgc
    86401 tttaattgtt tctattcctt taagactttc tatgatacta gaatttacag ctgcaccggc
    86461 tgccatttct tccctgttcg atttttcata gcttttcacg aaagcgaata ttgcaactac
    86521 ataaaaaggc aaagagcata gagtgattaa aaacaacgta ctattctgaa tagctaacgt
    86581 aaccccaaca agcaacacca taccaatatc taaaaatatt gataacgtag cacttgctaa
    86641 agcatcaata atcttactgg catcaagaaa acgagaaata atttcccctg attttctcgt
    86701 agcaaaaaaa ttcattggta aagttaacac atgtttgaaa tactgaagca taattgccat
    86761 actcattcgc tgtcctaaaa taataagaag ataactacga ctatattcaa acaatacccg
    86821 aaataaatag acagcgatca agccaatgga aattatattt aaagttgaac gtgcttgatt
    86881 agggatgaaa aaatcaagaa taccttgaaa ataatatgag cttcctatgc caaaaaacgt
    86941 aatgaaaatc gatgctaaaa cgatgtggaa tactaatcct ttttgtttcc aaattatagg
    87001 caaaaaagaa cttaatccag ctactttttc tttaatagga atataagttt ctctaggcat
    87061 aggtaataaa agaatacctg tccattcttt ttgaaacgct tcaatcgttt ttctattttt
    87121 tccattagcg ggatctgcaa tccatagtac gtttcccttc gttttataaa ttacaacgta
    87181 gtgcatatag ctgttatcaa ccaatatatg tgcaattaat ggtaagataa gatctctttc
    87241 tttccagatc tcactatctg cttgaatagc catacaatca aaagacaatt tttcaaatgt
    87301 ctttttcaat ccaaatgctg aagtaccctc taaatcagtc ccagataggt cccgtaattt
    87361 atgaatcggg atatcagttt taaaatattt taaaatcatc gaaaggcaag caacaccaca
    87421 atctttttca tcttgttgct gcacaaaagg aaatgatttt atcacttatc taacacaact
    87481 ccttctaaaa aatttttata gaaaaattct caatatagct ttaatacagt gaaaatattg
    87541 tctcataatt ccacaaaaac tttgaaaaca gttcttgaac actaactttt tcattcctga
    87601 atcaaattta ttttggaaat tttactattc aagaataaac ttgataagtt tcaggaagat
    87661 ttttactgtt aatcaaatac gtatgttaca gtagcaccgt aaaaaatatt atttaaagaa
    87721 gcgtgtttaa acatgcaaaa tgtaaaggaa ctaagtattg tggaaatgca caaactgttg
    87781 gtggaggcaa taatgcttgg ggaaaattgg ggcaagttgt aggtggactt accacagggg
    87841 cagtaggtgg tgcaggttta ggaacagcaa tttgcggacc agcttgcggt gttgttggag
    87901 ggttatatgg agctgtcgct ggaggtgctg cagctggctg ggatgctcga aaaaaataaa
    87961 aaaggagaat aagtagtatg catattaaaa acacaaaaac aacatttata ttatcttcag
    88021 aagagttgaa aaatattcaa ggtgggagtg ccgtgggagt tttaggcact actttttctg
    88081 gggcaacagc aggagtaaaa ctttgttcag ccggaggacc ttatgcaata gctgcttgtg
    88141 gtgtaggtgg agctttatta ggtgctggat tcagcatgtg gaccggtgcg taaacaatta
    88201 aaaaatatca aacctcaaga ttggtttgtg tcgattacga acataggtat gttctttatc
    88261 ttttcaaaag tttggaatgg acagaacttt ttactaaagc ttcttgtgct agtttttata
    88321 attatattaa atttttatct tttattaaag tcagataaaa attctttgga aatgtaatgg
    88381 tagagatatt tttacaaaag gacttgcagc gctgtagttg gtgctgcagg aggacctatt
    88441 tcggccgtta caggaggtat tggtaatgta cttgtcggat gtgcattaaa gcctgttcct
    88501 gcaagttaaa tttataaaaa caggaaagta attatctcaa atcctatcaa gtacaatcat
    88561 aggattgcac ttgacaggac aaatttttta actaaaaaat gaaaaacact ttctaaaaat
    88621 tagtagaatt tgccaaatct ttcgcatctt ccaccataca tttaatttta attccccttt
    88681 atggtactta ataaaaacaa gaaaagaact attcatttgg cccttttttg gttccagacc
    88741 atagaaatat tcctccagta actaatattg ctgttatgca cgtaactaat aacagctata
    88801 aaaattggta caactttaat aggattcaga aaaatttgca ctagtgaagg aatctatttt
    88861 attagaaaaa tgcaatctcc ctaaagaaaa aaccactaaa cagtgctttc tttcaacttc
    88921 tccttaattt tttgtgcttt ccctaaagta aagtttctgg ccaactctga atcaaaatat
    88981 agtgaacgtt ttttaaaatc tatttcttta acgttaaaga tatttactaa acacgctcga
    89041 ctaattcttg ttaacatagg atatttcttt tcaagctcac taattcttcc ataaaattcg
    89101 tactgcccat ctttagtaca caatgataat ctatgtggta attttgaagc ttctacaaaa
    89161 taaatgtcat ttatatcaaa agtaaatgtt tgagaaccta tggaaaaaac aaatgcttga
    89221 ttcgtaacct gttttgttgc atctatcctt tcttgcgcta ataacaataa ctcaacaatc
    89281 tcgtttcgat actcatctag tgtttgatct tttgttacaa atcctaacgt ttcaactctt
    89341 ctttttattg ttacgggtaa catctcatca tgagtagttg taaaaatgat ttttgcttga
    89401 acatcatatt ttctgattac ttctgctaat tctataccgt taacttcatg atttaaatca
    89461 atatctaaga aatatattcc ttgctttggt cggaattgtt tgaggtattt tttaacttct
    89521 aacggacttt gtgttttcaa tactatctta aatactttat cgtgaaaaag aatgaaatta
    89581 tcaataattc gttctaactg atttaattgt ataatttgat cttcacataa tattattgga
    89641 taactcataa atcctccttc cctcaaaaca acaaaataac ttgagtagta aattgatacg
    89701 gatcgttttg atagttcaca aacatattgg gattcttttt attgatttcc tctatactag
    89761 ataaacctaa cccttgatgt cccttttttg ttgttattcc ttttttcatt agagtatcta
    89821 tagagagtag tatctctcta caactattcg atatcgaaat ttctatctgt ttatcatctc
    89881 ggtaaatagc tagagacagt tctctatctt gactctctat agatgcttca attgcattat
    89941 cgagaataat tccaagcacc ctaatacagt caaatattgg aacaggaact tcaataatag
    90001 tacttggaca ttcgaattta caacaaatct tattgttatt tgcttggtat agcttcgcta
    90061 tcaacaaact tttcaaatat tcattttt
//
LOCUS       DAFLWQ010000004        64762 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.004, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000004 DAFLWQ010000000
VERSION     DAFLWQ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 64762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64762
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.004"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(63..728)
                     /locus_tag="L1V16_000261"
     CDS             complement(63..728)
                     /locus_tag="L1V16_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HBN1274630.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(875..1480)
                     /gene="dhaL"
                     /locus_tag="L1V16_000262"
     CDS             complement(875..1480)
                     /gene="dhaL"
                     /locus_tag="L1V16_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HBN1274631.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(1508..2518)
                     /gene="dhaK"
                     /locus_tag="L1V16_000263"
     CDS             complement(1508..2518)
                     /gene="dhaK"
                     /locus_tag="L1V16_000263"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBN1274632.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(2493..2939)
                     /gene="dhaM"
                     /locus_tag="L1V16_000264"
     CDS             complement(2493..2939)
                     /gene="dhaM"
                     /locus_tag="L1V16_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HBN1274633.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            3042..3362
                     /locus_tag="L1V16_000265"
     CDS             3042..3362
                     /locus_tag="L1V16_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBN1274634.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(3474..4343)
                     /locus_tag="L1V16_000266"
     CDS             complement(3474..4343)
                     /locus_tag="L1V16_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1274635.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(4439..5743)
                     /locus_tag="L1V16_000267"
     CDS             complement(4439..5743)
                     /locus_tag="L1V16_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1274636.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(5740..6249)
                     /locus_tag="L1V16_000268"
     CDS             complement(5740..6249)
                     /locus_tag="L1V16_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274637.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(6424..8559)
                     /locus_tag="L1V16_000269"
     CDS             complement(6424..8559)
                     /locus_tag="L1V16_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1274638.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(8642..10297)
                     /locus_tag="L1V16_000270"
     CDS             complement(8642..10297)
                     /locus_tag="L1V16_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBN1274639.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(10299..10613)
                     /locus_tag="L1V16_000271"
     CDS             complement(10299..10613)
                     /locus_tag="L1V16_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBN1274640.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            10783..11043
                     /locus_tag="L1V16_000272"
     CDS             10783..11043
                     /locus_tag="L1V16_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBN1274641.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            11057..11371
                     /locus_tag="L1V16_000273"
     CDS             11057..11371
                     /locus_tag="L1V16_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBN1274642.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(12101..12655)
                     /locus_tag="L1V16_000274"
     CDS             complement(12101..12655)
                     /locus_tag="L1V16_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBN1274643.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(12781..14710)
                     /locus_tag="L1V16_000275"
                     /pseudo
     CDS             complement(12781..14710)
                     /locus_tag="L1V16_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(15016..15732)
                     /locus_tag="L1V16_000276"
     CDS             complement(15016..15732)
                     /locus_tag="L1V16_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBN1274644.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(15733..17556)
                     /gene="glpO"
                     /locus_tag="L1V16_000277"
     CDS             complement(15733..17556)
                     /gene="glpO"
                     /locus_tag="L1V16_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HBN1274645.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(17570..19066)
                     /gene="glpK"
                     /locus_tag="L1V16_000278"
     CDS             complement(17570..19066)
                     /gene="glpK"
                     /locus_tag="L1V16_000278"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBN1274646.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(19202..20662)
                     /locus_tag="L1V16_000279"
     CDS             complement(19202..20662)
                     /locus_tag="L1V16_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1274647.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(20652..21947)
                     /locus_tag="L1V16_000280"
     CDS             complement(20652..21947)
                     /locus_tag="L1V16_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBN1274648.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(22279..22956)
                     /locus_tag="L1V16_000281"
     CDS             complement(22279..22956)
                     /locus_tag="L1V16_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HBN1274649.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(22986..24077)
                     /locus_tag="L1V16_000282"
     CDS             complement(22986..24077)
                     /locus_tag="L1V16_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBN1274650.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(24178..24612)
                     /locus_tag="L1V16_000283"
     CDS             complement(24178..24612)
                     /locus_tag="L1V16_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1274651.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(25196..26653)
                     /gene="ascB"
                     /locus_tag="L1V16_000284"
     CDS             complement(25196..26653)
                     /gene="ascB"
                     /locus_tag="L1V16_000284"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBN1274652.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(26650..28545)
                     /locus_tag="L1V16_000285"
     CDS             complement(26650..28545)
                     /locus_tag="L1V16_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1274653.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(28603..30378)
                     /locus_tag="L1V16_000286"
     CDS             complement(28603..30378)
                     /locus_tag="L1V16_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBN1274654.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(30428..31924)
                     /locus_tag="L1V16_000287"
     CDS             complement(30428..31924)
                     /locus_tag="L1V16_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1274655.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(32118..33740)
                     /locus_tag="L1V16_000288"
     CDS             complement(32118..33740)
                     /locus_tag="L1V16_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBN1274656.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(34068..35381)
                     /locus_tag="L1V16_000289"
     CDS             complement(34068..35381)
                     /locus_tag="L1V16_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBN1274657.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(35626..35850)
                     /locus_tag="L1V16_000290"
     CDS             complement(35626..35850)
                     /locus_tag="L1V16_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274658.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(35870..36292)
                     /locus_tag="L1V16_000291"
     CDS             complement(35870..36292)
                     /locus_tag="L1V16_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBN1274659.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(36434..37144)
                     /locus_tag="L1V16_000292"
     CDS             complement(36434..37144)
                     /locus_tag="L1V16_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274660.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(37162..37659)
                     /locus_tag="L1V16_000293"
     CDS             complement(37162..37659)
                     /locus_tag="L1V16_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1274661.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(37696..38148)
                     /locus_tag="L1V16_000294"
     CDS             complement(37696..38148)
                     /locus_tag="L1V16_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1274662.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(38283..38888)
                     /locus_tag="L1V16_000295"
     CDS             complement(38283..38888)
                     /locus_tag="L1V16_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBN1274663.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(39338..39958)
                     /locus_tag="L1V16_000296"
     CDS             complement(39338..39958)
                     /locus_tag="L1V16_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBN1274664.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(39960..40829)
                     /locus_tag="L1V16_000297"
     CDS             complement(39960..40829)
                     /locus_tag="L1V16_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBN1274665.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(40852..41259)
                     /locus_tag="L1V16_000298"
     CDS             complement(40852..41259)
                     /locus_tag="L1V16_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBN1274666.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(41278..42567)
                     /locus_tag="L1V16_000299"
     CDS             complement(41278..42567)
                     /locus_tag="L1V16_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1274667.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(42594..42896)
                     /locus_tag="L1V16_000300"
     CDS             complement(42594..42896)
                     /locus_tag="L1V16_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1274668.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(42921..45014)
                     /locus_tag="L1V16_000301"
     CDS             complement(42921..45014)
                     /locus_tag="L1V16_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBN1274669.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(45503..46267)
                     /locus_tag="L1V16_000302"
     CDS             complement(45503..46267)
                     /locus_tag="L1V16_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HBN1274670.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(46378..47247)
                     /gene="mdcB"
                     /locus_tag="L1V16_000303"
     CDS             complement(46378..47247)
                     /gene="mdcB"
                     /locus_tag="L1V16_000303"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HBN1274671.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(47272..48348)
                     /locus_tag="L1V16_000304"
     CDS             complement(47272..48348)
                     /locus_tag="L1V16_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBN1274672.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(48372..48965)
                     /locus_tag="L1V16_000305"
     CDS             complement(48372..48965)
                     /locus_tag="L1V16_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HBN1274673.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(48969..50645)
                     /gene="mdcD"
                     /locus_tag="L1V16_000306"
     CDS             complement(48969..50645)
                     /gene="mdcD"
                     /locus_tag="L1V16_000306"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HBN1274674.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(50635..50934)
                     /locus_tag="L1V16_000307"
     CDS             complement(50635..50934)
                     /locus_tag="L1V16_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HBN1274675.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(51036..52682)
                     /gene="mdcA"
                     /locus_tag="L1V16_000308"
     CDS             complement(51036..52682)
                     /gene="mdcA"
                     /locus_tag="L1V16_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HBN1274676.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(52689..53600)
                     /locus_tag="L1V16_000309"
     CDS             complement(52689..53600)
                     /locus_tag="L1V16_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBN1274677.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            53720..54577
                     /locus_tag="L1V16_000310"
     CDS             53720..54577
                     /locus_tag="L1V16_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1274678.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(54764..55126)
                     /locus_tag="L1V16_000311"
     CDS             complement(54764..55126)
                     /locus_tag="L1V16_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HBN1274679.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            55472..56911
                     /locus_tag="L1V16_000312"
     CDS             55472..56911
                     /locus_tag="L1V16_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1274680.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(56918..59470)
                     /locus_tag="L1V16_000313"
     CDS             complement(56918..59470)
                     /locus_tag="L1V16_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBN1274681.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(59584..60915)
                     /locus_tag="L1V16_000314"
     CDS             complement(59584..60915)
                     /locus_tag="L1V16_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1274682.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(60881..62359)
                     /locus_tag="L1V16_000315"
     CDS             complement(60881..62359)
                     /locus_tag="L1V16_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1274683.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(62664..64499)
                     /gene="tdc"
                     /locus_tag="L1V16_000316"
     CDS             complement(62664..64499)
                     /gene="tdc"
                     /locus_tag="L1V16_000316"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBN1274684.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
BASE COUNT        18456 a        13889 c        10979 g        21438 t
ORIGIN      
        1 acaaaccttc actcgcaagc cgagagtaag gtttgttttt cgcattgctt atttcgtgtt
       61 gtctattgaa atttttccgc acctagcttt tgatatagtg gtgctagttc ttgtaaggtt
      121 tcagcggtta tttgctcaac gtgttcgatt tcttgcggat agaagaatag tttacccatt
      181 tgaaaggttc ggtctctcat cgcttttttc aactcttctt gtttctttgt atcggacaaa
      241 tagtcagaca aagctaagtg gtcgtcaagt tcatgttctg gttgcggcca tatgtaataa
      301 tccttgatat cgactgtttt gctccactct ttcagtatcg caagcaactg gttatacgct
      361 gcaatgctac catatcgttc ttcgctttta taatgttggt acatcaaata gatttggtat
      421 tgtttttgat tcaacaaaac tgctagacag gcattctcgt cttgacgaga ttcgcttcgg
      481 tacgcgctcc aaaaatgact gcgtaaattc cagccattcg tccagctttc gattttaggt
      541 ttgctcatgc cgtacatatc aggcaaaagt gcagctgtct ggagctgaat ctctttccat
      601 ttttgccagt gttctttata ttctttcttg atttgttcaa tcttatctgt tggatggctc
      661 tctttgagct gtttgaatgc gtagattggt cgatcaaaca actgataatc tgattttcca
      721 agttccattg tttcgcctct ttccgttatc ttttgtattc tacctgaatt ttgcgatatg
      781 gacaaataga ggttgtgaaa aagctgttct gcatcaagtc ataagaacag ccaaacaaaa
      841 aactgcgatg agcatcaccg cagttttatt gaacttaagg ttgattgatc acatctaaaa
      901 gcgttgaaaa taaaatggca ctagaagcag ctcctgggtc gatatgtccg attgcacgct
      961 ctcctagata ggaagctcgt ccttttttag ctaccaagac tttggtgtgt tcttttgcct
     1021 ggtcaatgat ttcttttgtt aaattccctg ccttcaatgc ctctgtgact ggcagccaaa
     1081 catctaacat cgttttatcg tcagcttctg cctttcctcg gctttgaata cccgctgttc
     1141 cctgctcgat cacttcgcct aatttttctt gagaatcaat agaatcgacc tcttttgtcg
     1201 ctttcatcat gttcatgaat gcagatccgt ataacggacc agaagcccca ccgactttcg
     1261 atatcatcgc catagagaat actttgaatg tatcgctgat tgtttcagga tgatcggctt
     1321 gaaaagcttc ttcataagct gaaacccctc ttcccatgtt atttccatgg tctccatcgc
     1381 caatcggggt atctagatca ctgagatatt gtttgttctg attgattgcc tctgcaaatt
     1441 gcgtgagcca ttcttggatt tcttgaacgg ttagtttcat attatcaccc ttttatcttg
     1501 agatttttta ccatgaaatc gtctgtacat tgctttctaa agaatctttc cattgtgtct
     1561 ccgtcaagtc gatcagtgtt agagaaagac cttgcatatc tagtgaggtc ataaaattac
     1621 cgacttttcg gaaaactaca ttgacgcctc tttcttccaa cagagctaaa acatcattca
     1681 tgaacacgaa ctgttccatc aaaggcgtcc cgcccattcc gttgactagt acacctgctt
     1741 cttttggtaa attcgagtaa tcatctaaaa tcttagtaac aagttccttt gccagtactt
     1801 tagaaggctg catcttttct cgacgatagc ctggctcacc gtggatacca acaccatact
     1861 cgatctcatc ttctcctagt tcgaatcctg gtttccctac ttctggtaca gttgctgctc
     1921 gaagcgctag accgatcgtc ttagttgcct gtacgacctt ttctcccagt tctttcaact
     1981 cagctaggga agcaccgttt cttgctgcat cgcccacgat tttgtgtaca aggacagtac
     2041 ctgcaactcc gcgttttcca gcagtatacg tactattttc aacggcgata tcatcatcta
     2101 cgatcacact ttctacttca atatcgtcca tagcagctaa ttcctttgcc atatcgaagt
     2161 tcaatgcatc ccctgtataa ttcttaacga tcagcaaaac tccttttcca ctatcggctt
     2221 ccttaatagc cgtctgaatc tgatctggag ttggagaagt aaacacatca ccaagcaccg
     2281 ctgcacttaa catcccttcc cctacaaacc cggcatggga tggttcatgt ccgcttcctc
     2341 caccagaaac caaaccaact tgttccgctt tctgattctt ggctacaaca cgggaagatt
     2401 ctacacgatg aacaagttct ggatagcttt ttactaatcc ttccagcatt tcttcgacaa
     2461 tattgcttgg atcattcatg atttttttca atttattccc atcctttctt tccggcattt
     2521 tgtgcttctg ttaagatttg ctgagtatca tctgttatac cggcagtgat ggctgctgca
     2581 aaagctcctt ccactaaagg cgcatccacc agatgataac gttgctgctg ctcttcttcc
     2641 aacatgtctt ttgccagttc cgagttcaat accgcgctac cgatatccgc aaaaacaaaa
     2701 taactagctg catcgcttga ttcattgact gcttctacga ttttcatcgg gtctgatccg
     2761 atctcgccat ttattccgcc gagagaaaaa atttgcacct cttcggattt ttgcatctgc
     2821 tcaatcattt ctttaatacc atctgttact ttttgactat gagaaataag caaaatactt
     2881 tttttcacaa gaatcttcct ttcttttaca tagttgctaa cgattggttt cgctttcatt
     2941 aatgaacaat tcaagtatat aataaatttc taattttggg aaaatatgtg tagtgcttct
     3001 tgaagtttgt tatactttaa ttaaaagaga ggagtgatcg aatgattaca acaacaacga
     3061 acagtgtaga gggaaaagcc gtagtagctt ataaagggat cgtttttggt gaggtcatta
     3121 ctgggatcca tgcatttaaa gacttggagg cggggttgcg aaatatcttt ggcggccgct
     3181 caaaaagcta tgaaaacgaa ctaatgggtg caagagaaga agcacttgcc gaaatggccg
     3241 aacgtgcaaa agcattagga gctgatgcga tcattggcgt aaaaatggac tatgaagtat
     3301 taggcagcga caatggcatg ctgatggtca catgtagtgg aacagctgtc tccacgagat
     3361 aagtagggga catctgtttt aataactaaa gagagatggg acatgtagtg gcactcaaga
     3421 attagatttt tcagtctaac ttcgaggtac tctaccttcc catcctctct tttttatttc
     3481 tttttgcgga tgattccgta agctgctgcg actaacacac ccgcccctgc taaggaataa
     3541 ctgacagaag ctgttttttc atttgttttt ggcaaagtct gacttgttga tttggatggc
     3601 tctgtcgttt gctgaactgt ttctgtcgtg cttccagagg tcactgattt ttctcctgcc
     3661 gaatgcaaaa tatcttttat tcgttggaaa ctagctgcta agtcagcttt ttttgcttca
     3721 aaatcattag caactgtttg tgcttcgctg atctttccgt ggattgcttg actggccgct
     3781 gtgatatccg cttgagtttg acttagcttt ccagaagctg tttgagcaac ctgatttaat
     3841 tgctgattga attcttttgc ttgttggatc ttcccgtcaa gatctgtttg gacagcttcc
     3901 gcttttgctt tcgcttcggc aagctttttc tcaagttgtg cacggtcatt tcccacttta
     3961 tttttaagat cagctaaatc ttgatcgatt gctgcttggt cttctttcaa tttgtttttt
     4021 gcagcttcta atgcttcttc gagttctttt cttttatttt ccaagtcttg caaatgatcg
     4081 atttggtcag aagaggtaga actatttatt gatgtatctt ctgaagatga aatcgtttct
     4141 cctgaattat ctgtcggtac attggaagtc atttctgttt ccgaggcacc gttttcagca
     4201 ccagaagagc ttatggttgt tgaaggttct gtttgagcag gttcagaagt ttccgcaaaa
     4261 gctgtctgtc ccaataagaa aatactggaa acagcaattg gccagattaa cggcttcatt
     4321 ctttttttca tcacttttcc catccttact actttttaac taatttctta ttataagcaa
     4381 aaatgtttgg aagaaccata aacacaacag gctgtttgtc taaaaaacgg tgcatctttt
     4441 atttttttgt acgttccggg cttttccatg tcccgcttcc ataacctaaa atcgttttga
     4501 ctgctggaat gaaagtcgtc acgatcgtta tcgcgttcac tatccagaac aaaagcatat
     4561 atagtggtgc gaaaagaagg tatttcaatt ttcttcgtcg atcatctaca atcagcgaag
     4621 ctagcaactg gaaaaatcct gcgaccattt caaagcagat gaacacaaaa ctgaatgtaa
     4681 aagtaatata aatctgttcg tagtttcctt gatatacata atgcccgatt aatccagcaa
     4741 aaagaactac ggaaatacaa aagaatattg accagacaat actcaatgtt tgatcaatga
     4801 agatgatcgt tcttccaata tgtttaaaag gatggagcat cacttttttg aaattcgtca
     4861 gccagacttc tgttccacct tttgcccaac gttttctgtg tcgatatagc atcttcaacg
     4921 tcacaggtac ttccatgaaa aagataatct caggagcaaa aacagataac cagtcattta
     4981 actgatgatc ccaagcaata ctgatgtctt ctgtcgctcg atcttgtctg aatccgccca
     5041 catcgatcaa ggcttctttt cgatacatcg tatttgctcc actgtacgca taaagaccac
     5101 cgaaaacagc tgactgtgtt cgtttaatga tgcccacgat acttgagaat tcaaccgttt
     5161 gagattttgc aatcaatttg gtacgatttt ggacatccat atttgcagtg accgcagcaa
     5221 tatgtcttgc accagggcga atgaaataat tcacatacct aatcagtgca tctggctccg
     5281 gtaccgtgtc tgcatcattg cttaaaatca atttcccttt tgcaaaggca agtccgatat
     5341 taaacgcgtg ggcttttcct ttattttttt cgatccgaac cacacgaaga ttagcgtatt
     5401 ttttcatcag tctagctaat atttctggtg tttggtccgt tgaaccatcg tctgtcacta
     5461 atacctcata gttgtgataa ttcaatttcg tcatcaaata ctcgattgta tattcgatca
     5521 caatttcttc attatgggct ggcaccatga tcgtgatgaa cggttcgaca ctcaagggaa
     5581 catctaccca ttctttttgc ttatgtttgt ataaaaacac ataacaccag acaccaataa
     5641 accatacaaa tccgcctaaa atcggataag aaacgagaaa aaaatacata atagacaaac
     5701 aagtatctaa gaataaatta cctgtatggg tgattgagat catttcagtt ccaccccatt
     5761 ttctttatac aaatctgcaa tgaatgtcgt atctagattt ttctcttcgg agacagaata
     5821 aaaacggacc gtttctctct cttcttttgt tccaaaacgt tccgtataca cttcttcaag
     5881 taattcttgt ctttttttca atttttcatc ttcatattca aaagatttat ttactttttt
     5941 gtatagattt cgattgttcc acctagtcaa tacaaatgag gtaatcagga aactgaaaaa
     6001 aatcaataca aaaaagccga ttaagaaata cagcattttc ttttctgata aaaaagcgta
     6061 caaggaaaaa tccttggctc tttctggtct cgttaatggg aaaaagaccc atataaaagg
     6121 aagaacaacg atcatccatc ctaaaagagc cactaacgtt tgccaaatct ttaaccagta
     6181 attacctttt gaaaaatact tatctttcac caaaattgat gcaacttctt ctcttgttac
     6241 ttttttcata tcctcacctc acgttttttt gttacgacgt aggagtttac catacatttc
     6301 atttcttttc acataaagtg ttcctaaatt tttcctaaga aaaagaacaa aacatttctc
     6361 atcagcaaat gaaaaatatt ttgttctttt tatcagttgt tctttttatt ttttatctct
     6421 taattatgtt gctctttcca atacgacaat gcttttcatt cctctagata tcgccgtgta
     6481 catttgtctg cgtcttcttt gctcatctcc atcgttttca aatggatata agattacatg
     6541 atcaaattcc agtccttttg ctagactcaa aggaatgatt tggcagtttt ctaatccata
     6601 tgaatttttt ttaatcgatt cttgtagcgt ttgggtttcc tcttctgttt gggtgataac
     6661 tgccgctttt tctcctttta gagaaaccaa aatctcagct agtattttca acaattcttc
     6721 agaggatcga aaagagcggt attcgggttc ttttccttgc ggtcggatcg atacgatgtc
     6781 gatcttctct tgatccacag cataggtttt gaaaagctct gtgattgctc cgctagaacg
     6841 gtaactattt ctaagatcat accgatggat cggcagatgg tagtcgtcga aacaacgcat
     6901 aatatcagca aaagtagtgg aagaattaaa gattgcctga ttctcgtcac ctactaaagt
     6961 aaagtgagtt tttggaaata attcgatcaa tagacctaat tgtgccaggg tataatcttg
     7021 tacttcatca atcaatagat agcgaaatgc tggtacattt accttttcaa caagtaaatg
     7081 acgaatagct aatataatga ctgcttcatc aacagtacgt gtgggttgcc aagcataagc
     7141 tgagccatat cgtttttcat aaattctttc aaacaactga tgctcatcca cccatgccat
     7201 ttcttcgatt tgtctggtta tttttcgata ttttttttgt aaaagtttcc ttgcataagc
     7261 tacaatactt tgttccgaat catcagaaat caatttaccg aataattcca actgcctatc
     7321 ttctgtcaac gagagtacct gattctgcac agcaggactt tttgcttgtt tcaaaagatg
     7381 attcttccat tcgctcatca gtgccttttt cgttgcttga agcctatcga tcaatttagg
     7441 atgagcagga actttctcat atattttttc gatcgttttt ttagaaagga ctgtttttcc
     7501 atttttagta agtccacgga taaaattcgg atgatctaaa aacaaaggat ctgattgttt
     7561 tagattatcg ataaactttt tgctacgcaa acgttctgtc tgctccgata cattttctcc
     7621 cgtgatacgt ttgaaataag cctcttcacc ttctatttcc tctgctgaaa gctgtgaaac
     7681 cagctgtatg atggttagat tcagtggatt tctttcacct aatgatggta ggacattcga
     7741 aatatagtcg ataaaccgat gattaggtga tagaatcagc aagtcatcgg atgtcatcgt
     7801 atctcgatat aaatagagca gatacgcaat acgctgcatg atagcagagg ttttaccact
     7861 tcctgctacg ccatttacca agatattttg acttttcaca tcccgaatga ttgtgttttg
     7921 ttccgattgg atcgtagcag tgatagcctt catttcattg gtctcatctt ggcctaagac
     7981 ttctaataat acgtcatctt gaatagctac agacgtatca aaaaacttga ccaaacgatc
     8041 tctttccaaa agaaattgtc gtctttcttt aataaccgta tcgattttat tttgacgaac
     8101 cgtataagaa gatggaccaa tcatgttatt gtaaaaaagt tcggcaattg gtgaacgcca
     8161 atcataaaca agattttcat ctgcatcatc tgtgaaattt gctgtaccga tataaaagga
     8221 ttcttttggc tcattatcca gaaagtctac aacgactttt ccaaagtagg gacttttcaa
     8281 taaacgttcg atctttgcta gctgattttc tgcgtttttc tgtttgatat tcatctgatc
     8341 gatttctcta tttttcattt caatcatcga aaaagtatcc aggttatcta agtaactgtc
     8401 aaaattcaat cgaagctcgc cagccatttc tttcaacgac tggtttcctt ctatttttgc
     8461 cgtatccatc gattcccgca gttcgttttt tttatcaatt agcttttgat acacgttctt
     8521 cagatatgct tcttctaact gtttttgtgt gttgaccata cacattctcc tcttttttta
     8581 aagtggtgga accgattagt ttacctcttt taagagtcga atgcaagctt tttaacgagt
     8641 atcatttgtt aggatatatc agttcttcag gtcggacagt ttgatataaa gaaaatgcac
     8701 catcaaggtt ttttacgtgg tagccagact gcttcaagat tctttccgct agatagctac
     8761 gtaatccgct atgacagctg acgatatatt cttgttggct gtctaattca tttaatcggt
     8821 cccgaagttc attcaaaggg atatgtttgg cttccttgaa tttgcccttt tccaattctt
     8881 ctgctgttcg cacatctaat aaaatttttc cttttgctag ttctgtcggc aattcatgcc
     8941 attgtacggt ttcactaagc ccttctgcaa tgttcattgc tgcatatcct agcatgttta
     9001 ctggatcttt ggctgagcca aatggcggtg catacgtcaa ttctaattcc ggtaaatcga
     9061 agatcgtcaa atgccctttg attgctgttg ctaaaatatc gatccgttta tccacacctt
     9121 ttgccccaac accttgtgca ccataaatct cgccagtctc tggatggaag atcaacttca
     9181 gtaaaatatc tgttgcttct ggataatagc ttgcatgatc ttttcctgat acatgaatga
     9241 cttcaaaaga cagttcgttt tctttggctg ttctttcact taaaccggtg gatgcggcag
     9301 tcattccaaa cgttcgtata attgctgttc caataccgcc ttgatttctt cgagaaattc
     9361 cggaaatcgt gtccgcaact tgtctacctt gacgattggc tggtgaagca agagaaataa
     9421 gtgcatcttt tccagtgatt tgctgtttta caacgatagc atcccccacc gcataaatat
     9481 caggaatatt cgtttgataa cgttcgtcta ctaggatacc cccgcgtatg cctaattcga
     9541 ttccagcggt cactgctagc tggttatcag gacgaacacc aatggataaa ataactaaat
     9601 cagcagggat ggtacgccca tcatccagtc gcaatcgttt cccgtggtct tcaaatccag
     9661 cgacagcatg agaagtaatc acttctactc cttgatgaga caattctttt tctataaaag
     9721 ctgccatttc ttcatccagt gttggaagaa tatgtggtgc ttgttcgatc accatgactt
     9781 ctaaacctct tctttttagg ttttctgcca tttccaatcc gatgaatcct gcaccaacga
     9841 tcacggcacg ctttggctgt ttttctaatg catgcatcac tttatcgata tctggtacat
     9901 ttctaataga aaaaacattg tcggcttctg ttatccctgg aatcgatgga acaactggtt
     9961 ttgcaccagg agataaaacc aatgcatcgt actgttcaat gtgtttttga ccctcatgta
    10021 cgacttctac cgttttgttt tcgggaaaga tggctgtcac ttcatgattt ggacgcacat
    10081 ctaaacaaaa acgagcggat aatgattctg gcgtttggac aagaagattt tcccgttcac
    10141 tgatttctcc cgaaagataa taaggcaagc cgcaatttgc aaaagaaaca tacggtcctt
    10201 tttcaaaaac aacgatttct gcatcttcca ttaatcggcg aagccgtgta gcagcagaca
    10261 ttccacctgc tacacctccg acaataacga ttttcatctt atttccctcc tactgttcga
    10321 tcaaaccatt gattcatgcc accacgtaca ttcactacat cataaccaga tttctttaat
    10381 tctttagctg cttgtttact cctcatccct gattgacaaa tcacatagac ggtcttttct
    10441 ttgtctccat catatctgtt tatactttgt aatggaacat ttttagctcc ttttatatgc
    10501 ccgccccggt attctgcagg tgttctaaca tcaagtaacg ctggattttc caaaagcttt
    10561 tcctttaatt ctgggactgt tatcgatttt attgattgaa atagcaaatt cattttctgc
    10621 acctcattta catttttata aatacctcat ggggtatatt aaacaggagc tttattaata
    10681 tgtcaaccag aatgactctt catttttttc actacttttt atatttgcat aaaataccga
    10741 taaggggtat tatctaatta taaaaataga ggagaatgtg ttatggagat tgataataaa
    10801 aatatcctga accgtttgaa acgtacagag ggacaaattc gtggtatcca aaaaatgatc
    10861 gaagacgaaa aagaatgtat ggatgtcatc actcaattaa gcgctgttcg ttctagtatt
    10921 gatcgcgtaa tgggcatgat cgttgcagat aatctgaaaa attgctttga gaaacctgat
    10981 agtaatccag aagaacaagc ggctaaacta gaacaagcga tcaagatgat tattaaaaag
    11041 taaaggaatg atttcaatga aagtcgtttt ccatattgat gaattagaaa aatggtcaga
    11101 aacagggaaa aacgtaaaaa acctgataaa agcttctcca gaaacgacga ttgtcgtatc
    11161 tgtaaatggc atcgcgatta ccggttatct agactctgcc aatgcagaat tcttagattt
    11221 gcaaggagtc gtttttcacg cttgcgccaa tgctatgcgt gctaatcata tttcagaaag
    11281 ttctttacct gaacaagtaa tcgttgtacc agcaggtgtc cttgatttag ttgaactgca
    11341 atcccaaggt tatgcttata tcaagcctta gtcagtagag gttgcgacag aagtgatcag
    11401 cttcaagaaa tttcggctta tttttcgaag aagctacttc tggaaaaccg tgaatcaaag
    11461 gttgtgaaaa cgctgtcctg catcaagtaa taagaacagc caaacaaaaa tagcttctca
    11521 tatttttcgt ttggttgggc ttattaccgc agatgcaagc ttttgaacac cgtttaagga
    11581 agaggttgtg aaatcagcgg tttgacctaa gtattagaga aaaaaacggg aaaatagctc
    11641 ctcatatttt gccgtttttt gagctaatac cgaaggtcag ctgattgaac accgtttaag
    11701 gaagagattg tgaaaaagtc gcttagtttc gagtattaag aaaaattttg tgaaaatgga
    11761 tttctacatt tttgcataaa tttggcttaa taccgagaaa ctggcttttg aataccgttt
    11821 aaggaagagg ttgtaaaatc agcggtttga cctgagtatt agagaaacaa acggaaaaat
    11881 agctgctcat attttgccgt tttttgagct aataccgaag gtcagctgat tgaacaccgt
    11941 ttaccaagag gttgtgagcc taccatttaa ctccgaatca caagaaataa tttcaaaaac
    12001 aacttctcct gtttttggtt cggttggctt attatcgaga agtagctact gggagtctat
    12061 ttatcaaaaa aaggaatgcg acataggtca cacccctttt ttattttctt tgaaacatct
    12121 ttcggtactc gacagcatac aagacaaaag attgtaaaag accgtaagtg atgacggcaa
    12181 aaatgactct cacccacagc gttggtaatt ctgggaaaag cagcaaaagg atcatgccaa
    12241 catagatgac agcagtcgct actttgccat accacttcgc tccacttaat ttgatatttt
    12301 tagatagccc gattaatcca gctacaaaca taaagccttc ttttatcaag aatagaccaa
    12361 acaacagcca aagccacggt cgataccatg ccatagacaa aatcagaaaa agttgtgtca
    12421 atttatctgc aaacggatca agcaccttcc ctaagtctgt tacctgatta tatctccgag
    12481 caatgacccc gtctagataa tcagacaaac ctgagacaac aatgaccgct cctgctatat
    12541 aaaatgactg tctcagcaca aaataaagat aaatcggcag caaaaaaata cggaatatcg
    12601 ataaaagatt cggaatcgtt tgtatttctt tacgccagtc tgtgcttaat ttcattttat
    12661 cgccctacct cctcagcact cttttctttt tattttagct tacacgggga ataaaaccaa
    12721 tgatttcact gtttttattt ttctttacag acactgatat tatgagctaa tttgagataa
    12781 tcacttgctg ttttcatcgt ttactcttct ttcttcctgt cgtttgcgca tttcttttac
    12841 tagtacttta tgagcttttt ttgatcctcg ctctaggtca cgctgccgtt tacgtgtttt
    12901 ataatcgata aacagactgt ctaaatcgta acctgtcggg tacagatctt ctgctgaacg
    12961 caccagacga acacgctgac gaggcacgtg gattattttt ttgtctaaat atacatcaat
    13021 cgtatcttca cctatatctt cataaactaa cgcttctttt tggtattcat tgacaaatat
    13081 ccgatcacct tttgcaaaga gctgacgttc ttttttattc tccttcctat ttgtaactgc
    13141 tgtcttagga agaaattctt ttttctgtgt ccgataggct ttttccgcca agtaacgctc
    13201 tgcttgatgg atcaatttca tcgacatatc cattttatga gcaatccaca aagcttggct
    13261 ttctcctgtt tcttccaacc cgcaactgat atttaggacg aagtgcttcc cgatcgaaag
    13321 ccatagcagc cggcacaaaa tcttcatgat ctccggcgaa tttcttgatt tctccataat
    13381 gggtcgtggc aatgatcaat gccccttgct catacataga ttccatgatt gcgatcgcta
    13441 gtgcagcccc ttcatttggc tctgttccac tgccaatctc atctaaaagt accaacgtat
    13501 tcctttttat ctttttcaaa atagcagcga tgttttgcat atgaccagaa aatgtactca
    13561 acgcattttc taaattttgg tggtcaccga catcgacgaa aatctcatca aagacagcaa
    13621 gctctgtccc ttcttttgcc ggaacttgca taccgaacat cgccatcaaa gtcaataaac
    13681 cgactgtctt caacacgact gttttgcctc cggcatttgc tccggtgata atcaagcctc
    13741 gatagtcttt accgatttca acatccaatg gtaccgcatg ctcaggtaaa aatggatgtc
    13801 tgccttgctt gataatgata tgttccgatt tattgattct aggtgtgctt ccattgattt
    13861 ctcggctaaa ttttgcccga gcaaagatga tatctaacac cgtgatcgtt tcgatcaata
    13921 aatcgatcac ttcttcgttt tctgcgatag caccagtcaa tgccgccagg acttgatatt
    13981 cttcactgat ttcttcagct tttaacaact gatagtgttc attcaattta gaaatcacag
    14041 ttggttcaat aaaaaccgtc gttcttttat ttgattcatc gataatcgtt ccatctattt
    14101 tatttttata gctggctttg ataggaatcg tatagtattc gcctttttga acaatcattg
    14161 cttcttggat catttctttg tttttcggat gacgcaagaa tttcagtaat tttgactgga
    14221 tttctttttc gattagttgt aattgtttgc gtactttacg caaattacgt gacgcgtcgt
    14281 cactgacttt attatttttt attttctggt caatcaactc ttctacattt atcaaatcag
    14341 gaagatgttt gctataagca aacaacaagg gtgtctggta ttgattctta tcaaaaaact
    14401 ttgtgatcat ccgactgctt ctaagaaaat ccgcatattc gatcaaatcg gttggctgca
    14461 gaatcaaccc ttttttgact tgttctgtca gtgcatcgat cctcggcaac cccataaatg
    14521 gaacatgctg actgctttct aagatcaagc gtgcttctct tgtttcttct tgacgatcca
    14581 agacagtttg taggtttgtc gagaccgtca tatcgctgat tcgttttttg ctatagtttc
    14641 caattgctct tgcttggatt tcctttttga tccgatcaaa ttgtaattga ctaatcattt
    14701 cgttgtccat attctctcct tttcttgaag agatacctgt cccaaaataa ataagggcct
    14761 agagataaat aaaaggatag aacacagctt aaaaaagtca tgtcctatcc ttattagaat
    14821 acaaagatat tgttttcctg acaggtaccg tttcataagc acaccaaata aactttgttt
    14881 attggctatt cgacttactg attagatacc agctacactc acaaaacata ccccattctt
    14941 ctaggtctta tttattttcc acttaactat agcaagacac attttggttg tcaaacttta
    15001 gtatgtttta tagatttaca ccattaatga atagacacct accgcgataa ttgctccgat
    15061 cattggacct gcgattggta cccatgaata tgcccaatct gaagttcctt tattagctat
    15121 tggcaatacc gcatgtgcta atcgaggacc aaagtcccga gcagggttga ttgcatatcc
    15181 tgttggccct cctaatgaaa gaccgatggc taagatcaat ccacctacag cgaatacgtt
    15241 cgttccaggt gcaaattcgt tttgtccaaa agctagcaac ccaagaacta atacaaatgt
    15301 accaattaat tctgtgatca catttgctgg ataattccgt atagcaggac ctgttgcaaa
    15361 cgttcctaaa atcgcgcttt catctttcgt tgcattccaa tgtggcaaat aagaaagcca
    15421 aacaagaatg gcccctgcaa aagctcctaa aacttgcgca atgatgaaag gaacgacaag
    15481 attccaacta attgcccctg tcatcgccat agctagagag actgcaggat tcaaatgagc
    15541 tgggcccatg aatccagaaa tatagacagc cattgttaca gcgagtcccc aaccaaatgc
    15601 gatgacaatc cagccagaag cctgtgcttt acttttgttt aaattcacag ccgcacacac
    15661 accatctcca agcaaaacta ggatcagtgt cccaataaac tcccccatga tttgagtcat
    15721 atcactgttc atttatttct ccccctttag ttcccgcaga tctgattctg caatcaatgc
    15781 ttctaaacgt ttagtctgtt gcgccttctc ctcttctgtc cattcaaaat atccagcaat
    15841 tgcatcgatc acaggttgct tgatctcatc aagctgatct cgttcaaaca acagatgatt
    15901 tgtacgacga atgagataat cgcctggggc caaaaccatt tcttcttcta aaccataacg
    15961 taaccgagct gactcagcga gactcaaacc aggataaggt gccatttctt ttgctaattc
    16021 aaagatacgt cgggcattag tcccgtaaaa atcagcgata taagtagcat cttcttcctc
    16081 taaaccggct gctactcctt cttttgctaa ttctgtcact gtttcttcta atttagttgg
    16141 atcgaagttt ccacctgaaa tctgatattt tttagagtcg atttctttcg tctctattcc
    16201 gtattcttct tttaataatt ggcgtatcaa tcgcaaagct ccttctgcca tcttacggta
    16261 atcggtgatt ttcccaccag ataaagtcag caaaccatct ggttctcttt ctaaagaact
    16321 acctctggaa atcgtagaag gtgctttttc atcacggctg ttttccaaat ggttcaacac
    16381 gtcttctact tcagcacgag aaactttgtt ttccttatat tcacttactg tatcgacaac
    16441 tttattgaag ctcttgtctg aaatcgatcc attatctcca ccattgtaat cagaaccaga
    16501 attaccaatc aacagtggac gaagtcctgc ccagcttgct tcgatatcat tcaatgtgat
    16561 atttgcttct ggatagcgat gattgatcac atccaataga taatctacat cttcttgtgt
    16621 gactttcgga tccgtaaaat ctccttggta atccgtatct gtcgtaccaa agtaagtctt
    16681 gttttctctt ggaatagcaa aaaccatccg cccatcttgc tttcctgtat cgaagtatgt
    16741 gggttgcggt acaggcagtt ttttcgcatc tacaactaaa tggatccctt tagttggacg
    16801 cattttagga gagactggac gcgtaaaatt caagtttcgt actttatcta cccaaggacc
    16861 actcgtattg atcactaatt ttgctttgat ttcgatcact tcatctgtca gcaggtcacg
    16921 agctttgacg ccaacgattt gatcgccatc atataaaaag ccaaccgctt tcattttact
    16981 tactagataa gccccatctt cggcagcctt tttgatatta tcaatcacta aacgggcatc
    17041 attgttgcgg aaatctagat agacacccgc gccttttagc ccttcttttt tcaaaaacgg
    17101 ttctctttcc aatacttctt ctggtgtcag cgtataattc tcatatttgg ttcctgtcac
    17161 atttgccagt ttgtcataaa ggtccattgc tactttgacc gagaacatat tgaaggttgt
    17221 tgctccttcg ccctcataga ttggcaaaag cattggatct ggttttggga tgtgtggggc
    17281 aatactttgt acgactgcac gttcaccaac tgtgtcagct actacttcca catcaaatgt
    17341 cttcagataa cgaataccgc catgaacaag tttggtcgag cgagaggaag tcccttctgc
    17401 aaaatcctgc atttcgatca atcctgtttt gattcctgat gctgctgact ggactgccac
    17461 accggcacca gtgattccgc caccgatgat caacagatcc aattcttctt gctgcatttt
    17521 ttgaatgcta tcttgtcttg tcttgtttga aaacatatgg atttcctcct tattcaaatg
    17581 cttgggtagc ttttactgct tttttccaac cgttgtaaag tttttctcgg cgctcttcct
    17641 ccatttgaac ttcaaatagc ttgccagctt cataaaattc gcggatctcg tctgtatctt
    17701 tccaataacc gacagctaat cctgctaaaa atgctgcccc tagcgccgtt gtttccaagt
    17761 tttctgctcg ttggatcggt acattcaaga tatctgtttg gaattgcatc agatattcat
    17821 tgtttgctgc accgccatct actttcaata caggaatctt gattccagtg tcatcttgca
    17881 tcgtatcgat gatatctctc acttgataag caatcgactg taaagtagct ttaatgatat
    17941 cttcttttgt cgtaccacgt gtcaagccaa acatagcccc tcgtgctgcc tgatcccaat
    18001 aaggagcacc tagcccaacg aatgcaggaa caacataaac ctcatcttcg cttgtagagc
    18061 gtttcgctgc gtcttctgaa tcgctagctt tttgcaacat ttgaagtcca tctctcagcc
    18121 attgaatcga agaaccagcc acaaaaatac ttccttctaa agcatagtaa acctttccat
    18181 ttatgccgta accaattgtc gtcaataaat tatttttgga taattgcggt ttttcaccgg
    18241 tattcatgac aataaatgaa cctgtaccat aagtattctt gaccatgcct ggttcgaatg
    18301 ccatttgtcc gaataatgcg gcttgctggt ctcctgccat ccctgaaatt ggtgcttcgc
    18361 ttccataaaa atgataacct tgcgtataac cataaacttc tgagttagaa gtgacttttg
    18421 gtaacatcac tcgaggaata tttagtaaat ctaaaatctc ctgatcccaa tctagctgat
    18481 ggatattgaa caacatcgtc cgactggcat tcgagtaatc agtaacatgt gcttgtccat
    18541 cggtcagttt ccatactaac caagaatcga tcgttccaaa catcaattcg cctttttcag
    18601 ctcgttcttg cgcgccttct acatgatcaa gaatccagcg tatcttcgtt gctgagaaat
    18661 aggcatcgat cactaaccct gttttttcgt ggaaaaattc ttgatagcct tcatttttta
    18721 agttatctgc aattccagct gactgtctgg attgccaaac aactgcatga tagattggac
    18781 gtcctgtatc tttttcccat attactgttg tttcacgctg gttcgttatg ccaatcccag
    18841 caatctgatt tggtttgatc cctgattcga tgaacgctcc ggcaataact gactgtacag
    18901 aattccagat ttcatttgca tcatgttcca cccaactttc ttgcgggaaa tattgcgtga
    18961 actctttttg agaactgccg atgtgtcttc ctttcttgtc aaagataatt gctcgtgagc
    19021 tagttgtacc ttggtcaatc gccatgatat acgttgattc tgtcattgtg attccctcca
    19081 ttatatgcaa acgctttctt taactactct tatcatacta ctgttttaaa aaaagaaact
    19141 gtcaaaattt tattcttttt ttcttttttt gacagttttt tattatgaag ctatttttta
    19201 atcaattctt ttcttttttc agcgtctcta ttcttctttt caatcgaata atgtcgtaag
    19261 gtgacgcaaa ttctgacaga taatattcac actgtttttt gtttctctgg caaaatgtga
    19321 tcaccaaatc atattcttta ccttcttcat aacttccaat ctcaataccg ccgattcccc
    19381 tcagttctct gatcagatat tgttgaaaag caatacgata aatcggcaga ctttctaaat
    19441 cgattccaat cactactggt tttgcaatat aaaaatcgat catcaaaaga acattggcat
    19501 actggatcat caggtaacta agctcactat cttcagctct tttcctcggc aattgctgca
    19561 ccgctgtttc ctgtaatttc gccagtaact gtgttaagga atgcccgagc attttctgct
    19621 gctgttccaa aagccgatca cgctcataga cttcgatctt tccaacaaag aaaaaccatt
    19681 cattgttgat ctgggaaatt tggtagccta ctgccttttc ttctttgatt ttcaaacgac
    19741 gaggacgata atgccataac atcgtttccc gaatgtaagt atctaaaaca gcggttggta
    19801 actttttgct ccgtgtcaaa tcatactgat aaaatatttc ttcgtctact atcgaaaaag
    19861 aaacaaaaaa gctgtaaaac atcattgttt cgtatacatt cagttctgct gctgttcgac
    19921 taagatgcat cacgatgatt ggatcgattg cttgataaag ccggtccgac tgatagagta
    19981 atttcttttc tttcaaagtt gcgtacgtac ttttttcatt caatagtctt tttttcgtaa
    20041 tcccgagcca gcaagcaatc tgtgcttctg ctgatgccgt aaacgttgtt tctaatacac
    20101 ggtccaatcc tagaatgaac ggtctttttt ctggtgtatt ttgcaaaaaa agcggtcgct
    20161 gatcttccgg gatatattgg aatagttcat aataaaaata tcgtatctgt agctcttctc
    20221 cgtataattg accgtttttg atttgtaatc caaattcctc taagagctgg ttcaattctt
    20281 tgatctttcg aaaaacagaa gactcactga tattaaacgc tgtcgctaat cgaacgatgg
    20341 atacttgctg atgttctaat aaatagacga gcatcttaaa cttcaagctt tcctgcaata
    20401 aaaacaatag aattttttcc aaacttacat cttcgtccaa cacaagcagc gcctgatact
    20461 catttcgctg tacttctact tttttttcca tcattcggcc aatcaattca atatcttcca
    20521 aatattgatc aaacgaggct tttgacagtt ggacatgctc tctcaaacca ttgatagagg
    20581 ctgttccccc ttgcagaaca aggtttcgca aaatcaggat ctgtaactgc tcttttcttt
    20641 ctaataatgc ttcaatcttc ataggcagta ttcgccacct ttgaccacac catatctggc
    20701 acacggtatt ctggctggaa aaatagctca tgttcttcta actgttcaaa cgtccatcct
    20761 tcttctactg caattgtcag ttggtcaaga aggtggaaca tctctttttt gctttggagc
    20821 tgtgctccaa gaatcttttt ttcagaatca aatagaaatt tgagtttaac tttgctttga
    20881 tttattgctg taagcttgta gtctacgtat cctgtttcaa ttttttgggg ataaaaaatg
    20941 ctctcttctt ctgtcaaacc tacgcttcct aagaaatagc caaaccactg attgccgact
    21001 ggacgatagg ttccctgatc ctttgtctgt gagccactaa ttgtcttgct gacatttcgt
    21061 gctgtacgga cagcgttatt tactagagaa acatacattt tttcatttgt tggacgaaaa
    21121 gttacttgga tcgcatcgcc aatcgcataa acgtcttttt gagacgtttg caagtagtca
    21181 tctacccaga tcgttccatc atcattcaat gttaattgtt cttcccacat ctgattgtcg
    21241 ggacgagaat gattagccag caaaacaaga tcatagttct cctttctttt ttccgtctct
    21301 acaatagcgg tttcattttc ggtcaaagac acaacttgtt cttctaaaaa aagtgaaagc
    21361 ccttgatttt tcatttcctt tactaacggt tctgtcattt caggatctag ataacgaaaa
    21421 agaattgact ttcggctttc gtaaagatgg atttgttttt ttcttgatgc caacccttca
    21481 gctatttcga ttcctgcttg tcctgcacca ataattgcaa ttttctttgc attcatgatc
    21541 ttttgctgaa gagccgttac gttttgtatc tttttaactg ggtgaataag cgttgattct
    21601 gcagaaatat ttcgaaactt ttgatttgaa ccagtcgcta gaatcaaacg atcaaaatcc
    21661 aatttttttc ctcctgctaa aacgactttt ttttctttca atcctattac tgtcttttct
    21721 gtgtaaacat ggattcgata gcggtcagtc agttcttctt tcgtgatcca agaaagttgt
    21781 ttttcactgg taacctttcc ttttaatatc aaattgaacc cgctgggaat ccatcctaac
    21841 ttcgattgct tttcaatcaa atatatttca cttgttggca tcaattggcg aagataaata
    21901 gccgcatgaa tccctgcaaa cgacccgccg acaattacaa tgttcatctg cattcctctt
    21961 tcttataagg tgttctactg ctaacttctc aatcagaaaa cacagtattc ataactcgct
    22021 ttcaacctta tgatacatag cgatgcagca gaatcaaccc tctccatcat accgtgttct
    22081 aggtctgctt ctcaataatg tactagtgga cctaattgaa gagtatcatt tctgaagaga
    22141 tgtttcaaaa aatgtactct tataaaagaa aaaaactcgc cttttacgta cctctgtcca
    22201 aataggaaac agaaaagaac gaaaagacga gttttagcgt gtgtaatgta atagttagaa
    22261 tagacacatc atttattttt aattctttaa tgcttcaaca actgcttcgc ctaattgatg
    22321 agcagattga ggattttgcc ctgtaagaag ccgcccatca atttgaacca cttctgaaaa
    22381 agctgctcca gactgatagt ttgctccttt ttctttcaaa gcatcttctg ctaagaatgg
    22441 tacttcattc gttgtaccat ttgcttcctc ttcttcatta ctgaacccag tcactgtacg
    22501 tccagctaaa atagattttc cagactcatc tgtaactggc aacaatccta caacaccgtg
    22561 acaaacagct gagaccagcc cttcatttcg atagatttgt gaagcgactt tcccaagatc
    22621 tattgcttct ggaaaatccc acattgttcc gtggccacca gcataataaa ccgctgcata
    22681 atcatttgca tccacatcat caggacgtaa ggtatttccc aaggcccgat ttctgaaatc
    22741 ttcatcttca taataggccc aatcgatttc atccatattc aaaacacttt gcggttctaa
    22801 aggtacatat ccgcctttag gactgacaaa atctgcatcg atcccatttt ttactaatac
    22861 atcataaaaa tgagtcagtt cacttaacca caaacctgta ggacgctcga tcttttcgta
    22921 cttttctaca tttgttaata cgatcaatac tttcattttc ccatcctctt tctataaaaa
    22981 ttgcgttatt gataacgtgc tttcaagaaa ttatataatg ggcttggcaa ataaagctct
    23041 ttatatgctt cttcaaaagg tttcgttaca aattcatcct cacggttttc caataatttc
    23101 tctgcccagt caggatcgac gatcatttgc tgtccaattg ctgcaagttc tgcatatttc
    23161 aatacctgct ctacatcttc gcgattgcgg atcccaccga caccaactaa agggatcttt
    23221 ccttgaatcg tgttatggac cacttcaaga atcgatttat cgttgtattt atcagaacga
    23281 gctattcgat catacatatt taatgaaaca tgcagataat ctagttttga ctcacgtaat
    23341 cgttcaagaa gccagatcgt gtcttcaaaa cggatacctg gtgtttcata ttcttctggt
    23401 gagaaacgat accctacgat gaatggtttt ttagcatatt gttcaaccgc tgagaaaacc
    23461 gttgttaata attcttcaat aaaacgataa cgattttcca agctaccgcc ccattgatcc
    23521 tctcgtctat tcgaatgcgg agagaaaaat tgttggatca aatacgtatt tgctccatgc
    23581 aactcgattc catcaaatcc tgattcaatc gctctacgtg tggctttgcc aaatgcttgg
    23641 attgtttcaa cgatttcttc ttcactcatt gctcgtggtg tttccgcatc aggacgtttt
    23701 gctgcaactg cacttgcaga tacaggctgt tctccagata aagttgctcg acttgtcatt
    23761 cgtccaccgt ggaaaatctg aataatcgct tttgcgcctt ctccttggat tgctttcgct
    23821 agctcactta atcgaggaat catttcatca tgagcgatgc tgagttcacc tggccagcct
    23881 tttccgatat cttggacatt tgcagcacca gtaataacag caccaagacc tttagaacgt
    23941 tgtttataat aagtgatctc atcttcggtg atcactccat tgaaaaagct gagttgtgtc
    24001 gtcataggcg acagcatcaa tcggttcttc aattgaactc ctgaaggtaa agtaattgat
    24061 tgatcaaatt gtgacattgt cattcctccc ataattcgct ctgattaacc tatcgagaat
    24121 catctatcat taaaccactc gattagttgt acatgcaact aatttgctta aaaaatttta
    24181 ttttttttgt aacttatctg ttgcatcatt cattgtctgg gctaattctt tacttgcttc
    24241 atttcccaaa actgctttgt atgactgatg aagttcttcc cagctaccat cgacttcctt
    24301 agcaaattgg cgtccttgtt ctgtaagata aactaatgac aagcgacctt cgctaactgt
    24361 tttgacgtat cctttatatt ctaatttttc aacaaaacga gcaatcgttg atggggcgga
    24421 atagagcatt tgtgcaatat ctttttgtgg tattccatct ttttctttta atatcaataa
    24481 aataaaacca taagttggtg ccagacctgt ccttctaaac gcttcatcag ctaatttatt
    24541 caacatgcga tctagctttt tcacgctaaa gaaaagacat tcatctaacg ctttttcaat
    24601 tggcttttcc atttcatccc ctccattggc gtacatatca tagtatgatt tttatttttt
    24661 gtcaaaaaac acggaataat gtccgcctcc tctgtctaga tttgaaaaaa agaagtagcc
    24721 atcttcaaag aatttcggct tgttttcgac aaaactcctt ctggaacacc gtgaatcaga
    24781 ggttgtgaaa aagtcgttta gttttgagta tgaagaaaaa ttttgtgaaa atggctttcc
    24841 acatttttgc ataaatttgg cttaataccg aaaaactggc ttttgaacac cgtttatatc
    24901 agaggttgtg aaaaagccgt cctgcatcaa gtaataagaa cagccaaaca aaaatagttc
    24961 ctcatatttt gtcgtttttt gagctaatgc cgatggtcag ctgattgtac accgtttatt
    25021 gagaggtcgt gagcctgccg ttgaactccg agtcacaagg agcaatttca aaaaacagct
    25081 tctcatgttt tatgactatg gtgacttgtg atcgaggagt tggcaggaga atactgttta
    25141 ttcgtaaaga aggggctgtg acaagacttt tgtcacagtc ccttatttcc ttttattata
    25201 ggatttcgcc atttgattgg atgacttgtc tgtaccaatc aaatgatttt ttctttaacc
    25261 gtttctttgt gccattccct tcgtcatctt gatcaacata gatatatcca taacgttttg
    25321 acatttgtga agtagaagcg ctgacgatat caatgcagcc ccacgacgta taaccaaata
    25381 aatctactcc atctttgata gcttccttca tctgctcaat atgctgcttc aaatagtcaa
    25441 tgcggtaatc gtcttgaacg gttccatctt cttctacttt gtctatagct ccgagtccgt
    25501 tttcagctat gaacagtggt ttttgatacc tatcatataa ttgattcaaa gcaattctca
    25561 aacccttagg atcaatctgc cagccccatt cacttgatgg aagatacgga tttttaattc
    25621 ctccagttat taagtttcct tggacccctt cccaattttc tggatgagca ctgactgcac
    25681 tagacatgta gtagctaaaa gaaacaaaat caacagggta ggctgctaag atttcttcat
    25741 cacctacttc tatttttaag ttgacacctt tttcttcaaa cattcgttgc gtatacgctg
    25801 gataatatcc tcttgcttga acatcactaa agaacaaaga agttctttgc tgctcaattg
    25861 ttttttgaat atcatccgga tcacaagaat acggaacaag aagctgatag ctgatcatac
    25921 aaccgacttg tgaacctttg ataatttcat gacaagcttt tgtagctaaa gcacttgcta
    25981 taaactgatg gtgtgcacct tggtatttcg cttgttccaa atggggatgg ttttcttcaa
    26041 ttactcctac gctaacaaaa gggtgatgtt ttacacagtt gatctcattg aaagtcatcc
    26101 aatattttac tttattttta tagcgtttga atactgtttc agcgaaacga acgtaaaact
    26161 gaataagctt tcgattaggc catccaccat attctgtaac caaatataac ggcatttcat
    26221 aatgggaaag agaaacgact ggctcaatcc catattttag acattcgtca aacacttgat
    26281 cataaaaaaa taatcccgct tcattgggtg tttcttcatc accatgagga aaaattcttg
    26341 tccatgcgat agacatccga tagcatttaa aacccatttc agcaaataaa cggatgtctt
    26401 ctttaaagtg atgatagaaa tcatttccgt gtcttttagg ataataatac ttgctgttgg
    26461 gatcctgcgc cgcttttact tgctgatgcg tcatcatatg ccattgatct gtccattttt
    26521 ctttaggtaa atcgctgtcg aatgtataca catcagacac agataatcct ttttcatcta
    26581 catcccatgc accttcacat tgattggccg ctgtcgctcc gccccataaa aatccttctg
    26641 gaaatttttt catatcgatc cccctaaact tgctagtttt cttgtttgat tatttttctt
    26701 atgactagta atgatatttt tgaatctact actatttgta acaataacca ttgtggtcgg
    26761 atcatatccc tctttgatta attcttgcaa atctacttcc atcaataaat cgcctttacg
    26821 tacttttttt ccatcagata ctgcactttg aaagtatttg ccatttaaat tcactgtatc
    26881 aataccgata tggatcagta tctctgctcc ttcttcactg actaccccaa ttgcatgttt
    26941 cgttggaaaa actgttgaaa cttccccgtt tacagaactg tagatttttc cgtccgttgg
    27001 aatgatcgca aacccttctc ctaaagatcc actagcaaat gttggatcgt ttacttcaga
    27061 taaatcaatt atttcacctg ctgcaggagt acttaacact atatcctttg aggattcttc
    27121 ttcgatttca tccttgtagc cgaaaagaaa agttagcata caggaactga tcatcgctaa
    27181 gaaataacta gcaactagcc aaacaaatcc ttcaccaata taaatcggga aagacaaaat
    27241 acttcttgta gcaactgcca aagcaccggc tcctgcggca ccagctactc caccaaatat
    27301 agctccacat atacaagcaa tgtaaaatgg tcgtttatat ttaagagtca caccataaac
    27361 agcaggttca gtgattccaa ataatgctgt gataaatgca gataaagata aactttttac
    27421 tttcttattt ttcgttttca aaaatacccc aagtactgct cctgcttgcg cagctacggc
    27481 agtcatacat gctggaccta gcgtatcacg accgtagaaa gaaagattgt tggtcattac
    27541 tggtacaagt ccccaatgta acccaaaaat cactaacact tgccaaaatc cgccgataac
    27601 agcaccagat aaaacagggc taaagttata aacagctaaa tatccagctg caatcagctg
    27661 acttgcataa tctgcaattg gacctacaac taataaaata attgggacca tcacgatgat
    27721 acaaatgaat ggtgtcaata aatttcgaat actttcgtgc aagcttttgc gaatcttagg
    27781 ctcaatataa gaaagaaccc atacagctaa aattgctgga ataaccgtac ttgtatacct
    27841 tgctagaatc acgggcatcc ctagaaatcg caaggttatg ctatcactat atgcactgac
    27901 aatcgtagga taaacgagag ctgctgcaat aaccatagcg atgaaacgat ctgtattgaa
    27961 cttttttgca gcagtatatg ccaaaaatat aggcaagaaa tagaaaaatg catcagctgc
    28021 tgcattcaaa atgatataag ttcctgattc agtagttaat aaattcaaac tcgtacataa
    28081 ggcgagtact cctttgatca aaccacttcc tgccaagacg cctaaagtcg gggcaaaaac
    28141 agcggcgatc atgtctataa aagagtttaa aatgcctttt ttctcagttc ctctctttcc
    28201 actagatgca tcatcttcta gtttcatttg tttggataat acgtcataca cttcatttac
    28261 tgcatttcct actacgactt gaaacattcc tccagcttcg actacagtga tcacaccttc
    28321 tagttgctct accttctcct tatctgcctt cttattatct tttagggtaa agcgtaacct
    28381 tgttgcacaa tggtaaacat tgctgacatt ttcttcgcct ccgacaaatc ggacaatatc
    28441 tttcgctaat tgtgaatagt ccatttttac ttcccccttg ttaattaatg ccgtagcaat
    28501 ccttcttaca agataagtat agttcttaga aaacggtttc tccattcaat tagtacccct
    28561 tctaatagcg aacgaaactg tacaatagtg tgtatggttt acttagccga gcaaatcact
    28621 cactgcttga aagaaaacaa gtatatcgtt tctcttatag tcaaaggaga caaaaaaaac
    28681 acgcttgatc ttcctttgct gatgtataag tggtatctca agctgatact ctgtgatttt
    28741 tgtttctact tggcttttga taagacagca caacaaagtc tcggcattta acggaagcat
    28801 aactaggtca gaactaggag agattagttg ctgaatggaa tctatctttt tatggatttt
    28861 tatttgattt tcttctttgt agtaatgatc aagcagtttt gttttctttt tttcttcaac
    28921 tatggtcagc ttttcacgca aaatctgata aatctcccaa gattcaaact catctagaac
    28981 actaggtaga taaatcaaat catcccactc aaaaataagc tcttgctcag tagtcaaaat
    29041 tgcatcatat tccgttattt tgtttgattg atttttgaaa agatacactg gttctatccg
    29101 gcattctttg atccacatgt tcatactttg ttgaatctgt ttttttagtg tattcaaaat
    29161 actaattggc tggttactaa caatcagtat ctccccttgt tttcgaaaag gattcaacgc
    29221 ttcggcaaga tacaaaacaa aataagcgct ttcagctaaa ttgggacgta attgaaaatg
    29281 tattgggaag aaacgccgaa ttaaataaat ttctaaagga taacgggaga tgatcttttg
    29341 tacaaaatga ttcatggtat tatgtccggc atccatcctc gttttcattt gtttgatatg
    29401 ggttagcaaa aattctgttt catggaacaa taacgaaaca ggaagatcta aaaaacgaat
    29461 aatcgtttgc tcaaatgctc ttagattctt ctctatttct ttgttttttt catcattaat
    29521 catcaaataa tttaactcta atagtcgatt ttcaattgct tgtttttctt gattggaaaa
    29581 agaatagggt agttctgatg ataacttttt tgtgagggtc tctaccatcg gaataaataa
    29641 tgtatacctg tttgtttttt ctaaaagttc ttctcttcga agaatggtca aaacgagata
    29701 ccgagaaaat cgtatgaagt cctctcctga aacaatataa ttatatgata taagaacctc
    29761 ttttaatgtc ttttggacag tcggcatgat attggaaaaa attgtactga tttgttgagg
    29821 aaaccttgcg tgttggatca ccgtttctgt tccaacaaga gataagaaaa ttctttttga
    29881 attttcttca gcaatgattt ttagtccttt tgtcgacgaa acttccagtt ctaatttagg
    29941 attgcgctcg atccaacgca aaatcgtttt tatttgtaat gatacggctg tttttgaaag
    30001 aaagaaaatg tctgctatct tttgcatact gacataccct ttttgaaaca ataagtacgt
    30061 cacaatagtt gaagctcgga aatccatgct ggaatagatt ttatgtttcg tcacctcttg
    30121 tatgatttgc tgtttagttt cagattcaat tgattctaaa aaataacctg aacgtttatt
    30181 tgactggata atgattttct tctcgtagat agcaagcata tttttgattt cagtttggat
    30241 cgttttcttg ttggtaccta aagcttcagc taattcttcg cttgttatcc aatgattctt
    30301 atttcttaat actacaagaa tttggagttg tcgtttattt aagtccattt gcttacacct
    30361 cctctttgtt ataaacatac aggaaaaacc tctcaaatga caatagtcac ttgcagaggt
    30421 ttaaaaatca tttgaagaaa gatctatatt caaggttttt accattagac tggataattt
    30481 gtttataata ttcaaaacta tcttttttca atctcctaaa gcttccgctc ccatcatttt
    30541 gtctatccac ataaataaag ccatatcgct tcctcatttc ccctgttcct gccgatacga
    30601 tatcgattgg tccccaccat aagtaaccaa tgatttggca accatctttt attgcctcag
    30661 caatttcctg aagatgtatt tttagatact cacaacgttt tggatcgtgg attcgattca
    30721 attcatctgg tgcttcatct agtccaatgc cattttcaac tatgaataat ggtaattcat
    30781 aacggtctgt caattcattc atgacataac gaaaccctag aggatcaatt ggccaactcc
    30841 aaggttcggg agatttttcc ttcaaaaagg gattatcgaa accatttgct ccgccagtat
    30901 ctacgcgcat ttctgcttct tttttataga cagcgctacg ataataacta aatgcaatat
    30961 aatctgccgt gttagcttgc aagcactgtt cgtctccatc taacattact ggtgcacagt
    31021 cttcttcctt ccatgtcctg taaatataag ctggataatg ccctcggcac atgacatcgg
    31081 agaaaaacca tgaattgcgt ttaaattgca gtgaaccaaa tacattctct ggatcacagt
    31141 catatgcata agtcgctaat gcagaaaagc tacacataat acccatctta gcatttggat
    31201 cgattttctt taataattga gtagcacggg cgttcgctag aaacatatga tgacaggctt
    31261 gataaatcac tttttttgtt agtgtagcaa tgggttcaag tttatctcta gcagggaatg
    31321 taaccaatcc agcagctgca taaggcatac gaaaagcatt attgatctca ttaaaggtca
    31381 tccaatattt cactttccct tggtagcgtt caaagacggt ctgcgcataa aattcaaaaa
    31441 agtcgattaa ttttcgattt tgccaccccc catactctcc taccaatgct aagggggttt
    31501 cataatgact aagagtaatt actggctcga tatcatatcg atttaatgta ttgattagtc
    31561 tgtcataaaa tacgagacca gcctcatttg gcttctgttc gtctcctctt ggaaatattc
    31621 gtgcccatga gatgcttgtt cgaaaagctt ttaaacctaa ctccttcagt aaacgaatat
    31681 cctcttcaaa tcgatgataa aaatcaatcg cttcatgaga aagataatgg agtgattcgt
    31741 ctaaagcaat ctcccaaatc tttttttctt cattccactg aatactagga tgctggttca
    31801 tgatcccgat aagcgtatct gtcacattag gtaatttgcc gtcttccaac catgcacctt
    31861 cacattgatt agcagctact gctccgcccc ataaaaaatt ttctggaaat atttcctgat
    31921 ccataactat ctctcctcgc tatcaacaat ttcttacttg aagtatagct cgattcatca
    31981 aaacaagata ttctaactat ttcggcagaa gagaagaaaa aaattgaatg ctactcttca
    32041 tttttaatat ttatatataa caaatacata agacgatccc cgaaagaaaa cactcgttaa
    32101 ccatctaagc aaacgattta ttttacttcc aacacaaatg cttcataagg tcgtaaatca
    32161 actttgccgt ctggtaactg tttcagagga taatttgaca caataaccct taaagcttca
    32221 cgtggaatag tgaacgtctg cttttcactg gacatattac aaataacgag ccattgctgg
    32281 tcttcatata tgcgagaata ggcaaagaca tgctcaggcg tcttttccac taattcatag
    32341 tctccccaga cgatgatgtc atgttttcta cgcaaatcga tcaatttctt gtacatataa
    32401 aaaacagaat cttgatctgc taacgcttct tctgcattga tttctttata atttggattg
    32461 actcgaagcc atggaattcc agtagtaaac ccagcatgtt cacgggcgtt ccattgcata
    32521 ggcgtcctag cattgtctct tcctttcgcc ttgattgatt ccaagatttc ctcttttgta
    32581 aatccagaag aaatcctttc gttatacata ttgattgtct caatatcttt tgcttccgcg
    32641 atatcatcga ttgggcaatt cgtcatgcct aactcttctc cttgatagat ataaggggtg
    32701 cctttcatca tatggagcaa gatagcaaac atcttggcac tttcttttcg atacacatcg
    32761 tcatttcccc aacgagaaac aattcgcgga agatcgtgat tattccaaaa taaactattc
    32821 catccttcat cacctaaaga tgtttgccat ttggataata cttttttcag ttcagagata
    32881 ctcaagggtt tcaaatccca tttgtctttg ccttcttgct gatctaatcc tatgtgttcg
    32941 aattggaaga ccatggataa ttcatttctt ttaggattgg aataaagttt agcgatttcg
    33001 gtagttgctc cccatgtttc gccaacagtc atcagatttt tgtcaccaaa agttgcttga
    33061 ttcatttcct gaagatactc atgcagttta ggtccattac ttgtgatttc tttatccggt
    33121 tctttgccaa tcatatcgat cacgtccata cgaaagcccc caataccttt atcgatccag
    33181 aaattcatca tttgataaat ctcttggcga acctgtttat ttttccaatt caaatcaggt
    33241 tgacgcttgc tatacaagtg cagaaaatat tgccccgttt tttcatccaa ctgccaagca
    33301 gaaccactga atattgagcg caatctatta ggctcttttc cattgaccgg atcacgccaa
    33361 atataatagt cccgataagg attttcttta tttttacggg cctcaatgaa ccacggatgt
    33421 tcatcagaag tatgattcac caccagatcc atgatgatac ggatatttct tttctttgct
    33481 tcttcaatca gttcttccat ttcttccatc gtaccgaatt ctgccatgat tgcttgataa
    33541 ttactgatat catacccatt gtcatcattc ggagactcgt atactggaga aagccaaatt
    33601 gcatcaatac ctaaatacgc cagataatcc aacctggaaa taatcccccg caaatctcca
    33661 ataccatctt gatttgaatc ttgaaaactt cttggataga tttgataaac aactgaatgg
    33721 tgccaccatt tttgttccat gattttcctc ctataaatgg atgtttctat tttttgctta
    33781 atcatttatt ttagtctctc tcactaaaaa ttgtaacgct ttcaaatagc tattgcacct
    33841 tgttatcggt aacagaataa aacaaaaaaa cagctgagga aattccctca actgtttttt
    33901 gaaaggattg atttatgcag ggaagaatgc tgatttcaca acttctttat aaacggtgtt
    33961 cactcagctg tcccttggta ttagctcaaa aaacggcaaa atataagaaa ctattttttc
    34021 gtttttttct ctaatactca ggccagaacg ctgatttcac aacctcttta tttcacattc
    34081 aatatccaca tgaatcccac aaatacaaag aacagaccat acatgattgg agatacttct
    34141 tttcctcttt tagctgctaa catggtaatt ggatagaaga taaaacctaa tgcaatccca
    34201 tctgaaatac tataagtcaa aggcatgccg atcaagatca agaatgaagg gatcgcaatc
    34261 tctaagtttc cccattcgat ttgtcgcaaa gattgtgcca tcaatactcc taccataatc
    34321 aatgctggtg cagttacttg tgaagtaaca actgatagta atggagaaaa gaacaagcct
    34381 aacaagaaga aaatccctgt agtaatagct gtgatacctg aacgtcctcc aacggcgata
    34441 ccagctgatg attctacaaa tgcaccaaca ggagaagtac caaataagga acccgcaagc
    34501 atagctgttg aatcagaagc taaagctttc cctacacgag gcatcttgtt gtctttcatg
    34561 aaacctgctt ggtttgctaa tccaactaaa gttcctgctg tatcaaagaa agtcacaagc
    34621 aagaatgtca gcactacgac ccacatttga agagaattga tgtcccctac atgttttaat
    34681 gcaactaaaa atgttggttt caaacttggt gctgcggcaa caatttcaga aggcattgga
    34741 atcaaacctg tgaccagacc taaaatcgtt gtagctgcca tcccgatgaa gatgccacct
    34801 ggtacacgcc gaacaagcaa gatagcagtt acgactaatc caaaaatcgt caaccaagta
    34861 gaaccaacgt tgagtgatcc taatcctact aatgtagatt cattcgaaac gatgatccca
    34921 ccttcgctca gaccaaggaa agcgataaat agaccgatac cgccagaaat cgcatatttc
    34981 aaatctgctg ggatcgcatc aatgatcatt tcccgcagct tgaagattgt gatcaaaata
    35041 aaaatcaaag aagcaacgaa tacgccggct aatgctgttt cccatggaat ccccattcct
    35101 aaacaaacag aataagcaaa aaaagcattg atcccaagag caggtgccgt tccaattgga
    35161 taacgggcta atacccccat taaaacacag ccgatcgcac tggctaatgc agtcgcagta
    35221 aacactgctc cttcatccat tccagaagca cctaatacag ttggatttac aaataagata
    35281 taagccattg agataaatgt tgtaaatcct gccagtacct cacgttttac cgtggtgttc
    35341 aatttttcta tttcgaagta ggaaagtatt ttttccttca tcttccatcc ccctaaatcc
    35401 gaacattata aataaagtcc gttaaaattt cgatttatta ataaaacaac gtgttttatc
    35461 atatactaaa acaaaacata agtaaacaaa aaattcggat tttaagcaaa atccgaacgt
    35521 tccatctgat taaatccctt tatctcaaag ttcatgaaca ttcactttgg attacaagaa
    35581 tttctttatt gtgttaataa agtttcttca ttctagtctc aaaaatcaat agtgtgattt
    35641 gattttacca tttcgtttct gttcttcttt gatgaattct tttgtatcga caggattcag
    35701 attatttagt ccgccaaaac ctgtatcgac catttttccc cagccttttg tcttcttttt
    35761 tcctgatttg agattctttg ctcgaagctt ctcactatgt tttgctcgcc gatacttcaa
    35821 ataaccttct aatcttccca ttagatccac tgtttttcct cctttttatt caatcagacg
    35881 actcagcttt tcctataaca aaataattgc cttcagggtc agaaaaattg aaagtcaaga
    35941 tgccattgtt atctgtgatt tctcctggtt cttccatgtt ctcgtagata gtttcaaatt
    36001 catccgtaaa aaatactaaa gaaggcggtg gtcctaatac ctctggtgaa aacttctgca
    36061 caaatacttt tgggaatacg cctaattcta attcttttga gatgctgagt acaatactct
    36121 taaattcttc tggcaattcg attgtttcag aaatttctgc accaattttt tctacaaaga
    36181 atcggcaaat catctctacg tcattgacat aaagcatcac acgtgttttt tgtatcatca
    36241 tttgaccctt ctttctattt gattttcttt cctgtctata aactgattcc attatatcac
    36301 gaaagcgcaa acaccttgtg tttgatacta ttcaagaaaa ataaagcaat agtttctagg
    36361 attgctttcc tccacaaact ttttttacaa aaaaaaaacg gcaatgaatg ccgctcttct
    36421 tatttcgatt cttttataat tctgcttctg attcatcttt ggttagtgtg tgtctaacac
    36481 tagttacgcc aaatgtttga tcgatttttt ccttcaacgc ttcgattgcc tgtgcgccac
    36541 gtgccgcttg ttcagcattg atggattcaa tgaccagcac cgctgcttgt gtttcttccg
    36601 tcagcatcgt tctttgggct tcacgccagt tgagacagcg acagatcgct ccttgttcat
    36661 catagtagat gatttcttcc ggaagtgccg gagcatcgga atctgcacct aaaggcagga
    36721 atgattcgcc accttgggct tttcctaaat gcagatttcc tgcgatcttt tcgatatctt
    36781 ctccgccgca aggtacgcca aaagacaagg aaatactatt atagatatct acaagcggat
    36841 tgattgggaa aaattcccgt tcttgatttg cacgtttcag taaagcttca atagaagaac
    36901 gtgcaccttt tttagtcttg aatgtggtaa atgcctgacg ccactgagca atgacttcgt
    36961 tttggctgaa tgtttcttct gtaaggtaat ttcttgcttc ttttgctgcc tcattcaata
    37021 attgatgata cgtttcttca ctttcttttg ttacgtggtt atcgatacca tttacggata
    37081 agatttcgat ggttgcttca ggaaatactt cccagaaatt ggtatccact attacttttt
    37141 tcatctgttc acacctcttg attagaataa ttgcttgatg aatagatagt ctgtttgggg
    37201 atcatctccc atataaaaaa catgttcgct gtatttgata aatccttttt tacgataaaa
    37261 agcgagcgca acatcgttgt gttcccaaac accgagccaa atggctgttt tttgcttttc
    37321 ttttgctttt tcaatagctg tatctagtaa aaatgtaccg ataccttgat gtttaaattt
    37381 ttttcgtaca tagattcgct cgatttctaa aaaatgatca gccatttcct cagattgact
    37441 cgttcctgta tttagtttca ggtaacccgc aggctcttga tcgatactca ctaggaaaaa
    37501 atcggtttct ttatctttta gctcttctgt aagtttttct agtgcataag cttgtgtcaa
    37561 gtaatcagct aaatgctccg gtgaattatc ttttccaaat gtatctgtaa atgtttcgat
    37621 actaatttgt tgtagtaagt ctacatctga aggcgtcatt tttcgaattt cgtatttatt
    37681 cacggcttct tcctttcaat agatcctttt attgcctttt ttgacaaaat tccaatcttc
    37741 gctaacattc ttgcatactt tatttaaaag atattccaat tgttttgctt cttcgtcaga
    37801 aagaccattt aatgcgactg cattggagta gttgttttct cgaatgatga aaggatagat
    37861 ttctgctcct tttttagtcg gatagagttt cttgattttt ttattttctt tatcttccaa
    37921 acgttcgatc atcccattgg attctaattt cttgattgct cgggcagtcg ttgtacgatc
    37981 tactttgatc atttctgcta gtttttcttg gatgattcca ggattttcgc aaatacgtac
    38041 taaataaaga tactgtcctc ttgttaaatc gacttctttg aattcgatat tgctaataga
    38101 atctagcgct cgggcaatca ttccgatgtc tcgaaggatt tcagccattt catcccacct
    38161 ttattttgtt tgtaagacta gttcacctct ttttgttgca aatgcaacta ttttcaataa
    38221 aaaaatcaag ttctttttta ataactagta aagtatattc ttttcttctt ttacgaaaaa
    38281 gctcaatcac aatagatctg gtttttgttt tctaaaataa gtaactgttt cttcgttgtt
    38341 cgcttttctg atagctttgg caactcttct atactaaaaa atcccatgtt ggaagtttca
    38401 ttattctcaa taaacttggc ctcttcaccg tggatcgcac aagcaaaaac aagtttataa
    38461 tactgaaaaa gctgtggaat atctttttgt ttattcgtat caaaaactgc tcgcaactga
    38521 gtagtttcta ctgttaatcc tgtttcttca tagacttctt tacgcacatt ttcttcagga
    38581 gacaatccta tttcagcaaa tccaccagga agtgaccatt ctttcgtccg tttatcttcg
    38641 attagtagga ccttgccatc ttttttgata taggcacgaa catctacttt tggtgttgga
    38701 tgtccttctc caatcgttgt gagcgctttt atttcttcga aagtttcttt tcctatttca
    38761 ctgatcagtt ccaatgaaat cgtccggatc tcctcaaaac gctctttatc aaatacatct
    38821 tttccataat atagaccagc ttgagaaagt gcgagtagtc ttttgtattg agccaacttc
    38881 ttgttcattc tcttcccttc ttttttagca aatgtatgac tatgtaatca agtatagaag
    38941 actggtttaa ttacggcaaa taaatataat gaaatctgca ataaataaaa gaatgttaaa
    39001 aaactcgaga acaaaagaca ttcgacttct ctggggctgt gaataaatgg cgttcaaaag
    39061 cttgcatctg cggtaataag ccccaccaaa cgaaaaatat gacgagctat tcttgtctgg
    39121 ctgttcttat taattgaggc aggacagctt tttcacaacc tccccactaa acggtgttct
    39181 cctaccaact cctcggtcac aagtcacaat attcatcaaa catgagaagc tgtttttttg
    39241 aaattgctcc ttgtgactcg gagctgaacg acaggctcac gacctctcgg taaacagcgt
    39301 tcaaaagcca atttttcgat attaagccat ttctttgtta cttattgtca ttgatttctt
    39361 tttctaattt atccaatagt ggagtgtaat ccacttgagt atagtctgtt acatcaaatt
    39421 catatagtgt tcctaactgg aatttgtcat attttcggtc ggcgatgatc tttttgaatg
    39481 cttctttcgt aatatgattg gtccctttcg ttcgatcttc caatacgtca ccatagtgat
    39541 aatgatccat gatatagctc aaatgacgat ctgattcacg atcacgtttg taccgacgtt
    39601 gccataacac ttcaaagtct gctgttaggc gaatcgtgat cacctgatat ccgtatctat
    39661 ctgctaattc ttggagtcgt gctttttgct tatcactaaa aggatactcg gacacaatca
    39721 ctttctttcc tgcttccata tacaaatcaa gtgctttgta atagaaagga taaactttcg
    39781 tcctttcttg ttccgcccgt tcttccaaat tgttaaaccc gatggattct gcatagtatt
    39841 ccttgatttc atcgagcgtg atggcataca tatctggaaa tcgttcccgt agtttattca
    39901 taagatatgt ttttcctgta ccaggactac cagccagaag aatgaaatac tttttcatct
    39961 catttatttc ctaagttaat tggactttcc aagttcataa acagtccaat cttatgcttg
    40021 acaatttctt ttactgcttc atttgctgga atcacattat ggcgaagaga cttgttgatt
    40081 tctgtttcac taaaggtttc tttagctact ttcgtccagt tgactaaaag ctccgttcca
    40141 acattgaatt tgcggatccc gttattgatc aattcaggat aatcttcttc tttcacacct
    40201 gttcctccat ggataactag ggggacatca actactgcat cgatttcttt cagcaaggga
    40261 atgtttactt ctgtttttga tttgaattgt ccatgattcg taccgatagc aatagctaat
    40321 gcatccacgc ctgtagcttc tacaaatttc actgcgtctt ccggtcttgt atataccttg
    40381 tcattttcag cgacatggat tccttcttct gtaccgccga ttgttccaag ttctccttct
    40441 acggaaacac cgtgcgcatg ggcatattct actactgctt ttgtcttcag gatattttct
    40501 ttgaaaggca gatgggaccc atcatacatg acagaagtat atccgctgtc gattgcttct
    40561 ttgatatcat caaagtctcg ggcgtggtct aagtgcaaga ctgcatcaac catttcttct
    40621 tctgcaatag ctgtcattac attgactaac acatgcatgc cgatatattt agcggtatcg
    40681 acacttgttt gaataatgat cggcgaaccc atttcttttg ctgcgcctag catagcagga
    40741 agcatttcta ggttatgcgt attaaaagct ccaactgtaa aattcaactc ttctgctgtt
    40801 tttgttactt ctttcaatgt tgtatacatc ttttattgcc accttatctt tttatttgtt
    40861 tcctttgatc gttacttgtt ttgcaatttg tcgcatctca tccattttgc ccatgtagta
    40921 atcgatccct tgatcatcac cagcacgagc agcatctgca cgcttctggt tatagaggct
    40981 catcagtttt ttatacccat ctccgatcgt ctgtttattt tccaaactct tttctaaata
    41041 ttggatggct tgatcgttca catacaattc agaaaattta agtccaactt gttcataaag
    41101 tttcgctaat ttatgcttat cttgggtagt ggaaatctct tgtttcaatt gtgtaatctc
    41161 tgattgaatc ttttcggtcg cttctggcga tagggctttt tcttcttttg ccagaacttt
    41221 tttcggttct ttttcttttt tcttaaaaaa tccaaacatc attttcccta ctttcaatta
    41281 aaatgctttc aaaactgggc ttaagatcca ggcatataag agtgctgcgg ctactgtatc
    41341 tacatcggtt gctgtagcat tgttgaatcc catcgaatta aagatcgtta ctagcaaagc
    41401 gggcaataat gtaataaaga aaccatgagc aataccgcca atgatcgctc ctcggcgtcc
    41461 gccaactgcg ttgccaaata tccctgctgt ccctccggca aagaaattgg ttagcatacc
    41521 aggtaaaatc atcgctaagc cgaacatggg caaagtaaac atggcaataa tcgtaccaat
    41581 cgttgtcgta atgaaaccta aaatgacagc atttgggcta taaggaaaga aaactggaca
    41641 atctaaggca gggatcgcat caggaactaa tttcatagct atccctcgaa atgccggcac
    41701 gatttcacct aacagtagac gtacaccagc tagcaataca tacacaccca ctacgaattg
    41761 gatggcttgt aaaaaggcaa acatgatata gttttgatct cctgataatt cagaagcgaa
    41821 tggttcgcct gcaaataaaa cagtgatgat atatagcggg accatcacga ccatgacaga
    41881 caaataagta tcttgcagaa attcgaaatg tgtcggcaac ttgatatctt cgatcgactt
    41941 tttattttcg cctttctcac caaaaagctt agcaacaccg gcttcaaata agtacccgat
    42001 cgtacaaaaa tgacctaaag caatatcatt tgatccagtg attttacgaa tgatcggttg
    42061 cgctactgcc ggcatagcaa tggcgaaaca agctccgata aaaccaccga ccaagatcaa
    42121 tacgatccct cgcagaccgg caaaatagcc aaagactgtc gtcatcgttg ccatccataa
    42181 aattgcttga ccagttaaaa aaatgtactt ccattttgtg aaacgagcca aaataatatt
    42241 gaatacaaaa atggctaaga acgtcagtgc aatatctcta cctaaaccca aatcattcat
    42301 tgcttgacca ttgatagatt caatagaagg gatgatccct tgcatatgaa atccttcagt
    42361 aaagattttc ccgaaataag ttaaacttcc aacgatgatg ctcgaaccgg cactcaacac
    42421 ttgaaatcct aggagtgtct ttaacgtgcc agagatgact tgtcctgctg atttcttctg
    42481 cagtagtaga cccaacatag caatcaatgc aatggtgatc gatgcctgag tcaaaatatt
    42541 ttcgatgata aaattgataa cgcccatgtt tttaccctct tttctttttg tatttagata
    42601 actcccttat cttgcagaac tggggtgatt ttttcttcaa tttcattttt tgaaacaata
    42661 tttttcaaat agatcatcgc cgttttagga tcaactgcga acttttcgaa ctgcgaacga
    42721 aaattttctg ctgtgatgat cacatctggt ttcatggaaa ctgcggaaga aatatcacaa
    42781 tggtccagtt tggcttctac tcctaatttg ttcaaaacat cctcagcaga catctgtgct
    42841 gcaaaactac ttcctaaacc tgcaccgcat acgaataaaa tgttcaattt gttcatcttt
    42901 gttctccccc gtatcattta ttatttctca actactgaaa aaagcagttg tttgaaatct
    42961 tcgatatttg tgcattcaat caatcgatcc aacttctctt cgttgttgat caattcaatt
    43021 agttctttca tgatgttcag atgcgagtag gagtctactg ctgccaaaca aaaaataatc
    43081 tttactggat ccatttcagg attaccgaaa tcgattggtt gctcaatcgt agctacgctg
    43141 actcctaatt tattgacccc atcttctggt cgggcatggg ctagtgccat gtgtttgcca
    43201 atcacgatat acggtccgta atcattcact gcacgaatca tcgcttcgac atagcgctct
    43261 tcgacaatgt tttctttaac caatggtcta gcagctagtt caatcgattc ctcccaagta
    43321 gtggcttttt ctttgatcat gatattgctg tccgtcaaaa tatcttttaa cataggctgg
    43381 atctcccttt tgttgatttc taaattgttt gtttcgaata atttttctaa cttgccatag
    43441 atgattcgat ctactcggcc accactttct ttcatgacat ctattatttg agtgaataac
    43501 tccgtcgatt catgactgtt aggctctaac cgctgtagtt cttcatttct tttcaaaaag
    43561 tcttctataa ccaagatatt cgtctcagtt aaaatcggat cgacaactaa aagcggctta
    43621 tttcgataat tcaattgaaa ggtgctgaaa accagattga catccaattt atctactaat
    43681 tcgatttctt ttgaacttaa aactgcagta atctcgatct gaggaaactt ttctttcaga
    43741 ttctctgcta acagatttcc agtagccatc ccatggttac agacaacgac tgatttataa
    43801 acataattca agtctcgctt gattacactg gcgatcgtcg aaaagtggat gacaagaaaa
    43861 gctatctcgt cctccagtat cttgccacca attacttctt cgatcgtagg aacaaaatga
    43921 gtgactgcgc ggtagattgg gaaataattt gttcggatgt tttctttcaa tggattcatg
    43981 acttggatat gattcttgat tcttacaatc agtgcagcca tgtgcttata gagattttcg
    44041 aataaagctt cttcctttag atggaaaggt acgtgtgtct cgttctctac aaattggatc
    44101 aattggatcg ttagtaattg agcttgtacc cactcgattg aattggagat atctctagca
    44161 ttgaacgtct caatagtgaa acgaagataa tttctttcta cttgcgggac attgtccaat
    44221 tgaaattcct cgatcatgtg gtcaataaat gcagaaaagc tactgtcttt tatttctgta
    44281 tttttccaat taatggcaga gataaattca tgtttcctga ttcgctggat ccagatcaat
    44341 gtaaaaagca ggatttgttt tttataaata tcatcttctt gtttcaacaa cttattggaa
    44401 tagatctcct gtattttttt gatttccacc aaaggaaaat aatggagaaa gattttttga
    44461 gccggtgtta attgtgcatc ttgattcata aagaagtcgg tcattcccag attctgattg
    44521 ataaaatcat agatcatcgt acggatagat cgttctgaac ctttataaac cagtccttgc
    44581 tttccataac tgacgatctc tatcccataa ctgaccagtg ttgctcgtaa ccgtctcata
    44641 tcttcatcta atgtactttt agagatttga aattcttctt cttttttgtt tagatggatc
    44701 gggattcggc tgtaagcaac ggctaaaact agatcaaaaa tacgttcgcg ccgattcaaa
    44761 aagccgtctt tcacatcttt tatttcagtt tctaatcgag cttgcttttc cttttccagc
    44821 ttcaacaaaa aacctttgtt gcgaattgta cggatctccg gaagcttttt actgctcaac
    44881 cagatattcg cttcaagaac ttcctgacgg atcgtccgct gactgacatt gaactcactt
    44941 gctagatgtt ttgcttttac tggatattgg gctgtcatga ttctgtgaag tatttcaatt
    45001 gttcttgttt tcatagaaat gatctccttc tgatttcaag tatatggttc cgcttacata
    45061 ataaaaagta gatatttctg ccacttgaag tggaaagaaa gtaagcaaag caaacaaaaa
    45121 ataagccata tgctttttca tctcctcaac gaaaaagaca tacgcctatt attacaaaaa
    45181 ttttgcccat ctatacaaaa aagaggttgt gaaaaagctg tcctgcatca agtaataaga
    45241 acaactaaac taaaatagtg cttcctattt ttcgtttggt tgttcttatt atcgcagatg
    45301 caagctttta aacaccattt agtggagagg ttgtgacaga gatgttcagc cttgagcgat
    45361 aagaagcgat tttgaaaaat cgcttcccat attttacaaa atcgtgcctt attgccgata
    45421 ggctatctct ggcacaccgt ttattcagaa aaaggagctg cgacaaggct tttgtcacaa
    45481 ctccgttcat aaatatttcc tgtcaatcca gcataatcgg ctgaataaaa tcggcttgcc
    45541 atcttttttc tttctcagaa aaatcaaaat accatatctg agaaaaatac tgtcgttgtg
    45601 tcttacttcc tgagatcaat cgcccatctt ttcgatcgac tgaataatca cagcatctga
    45661 aatcaattcg gatggcaaaa ctattttcgt ggatctgtcg ataatttcct acttcctgaa
    45721 tagttatttt tttagtatga tttcttacac cgtctgcttt gtttttttgc agaactttct
    45781 gatgttcggc aaacagcttg tctgtataac agcttctggc tttttcagga gtttcttctt
    45841 cccaagcgga ttggatcttc atgaatatct tttggatttc cagaaactgt gctttctttt
    45901 ctttagccgt tcctgacatg cgggacaata tctccgcttt cagccttttc ttttgtcttt
    45961 tattcttgac gatagaaaaa gcagaaaccc ctcctactga caaaacagct aatgcaagaa
    46021 atcccgtttg ctcataacta gaaggacctg tacctggacc ataataccca taagaatctc
    46081 tgccgtaaga acgactgcca aaataactgc ccccatatga acgaccacca aatgaacctc
    46141 tgcccgaact tcgaccgcta gatgtacctc caccatgacc acccgcgaca gcgaatcctt
    46201 gggtcggcag agcaaacaaa cataggccca ctaacaaaat gattgctaaa taattgattt
    46261 ttttcattgt cttcctcgtt atcttttatt acaaaaaact atttttatga tagccttgct
    46321 aaaaggaaga gtcaataacc agatgcataa actgtttttt tagcaatttt gtcttattta
    46381 gtcattgagt aacatcggac aaatgtatgt gtcggcagtc cataattcct ctatcttcag
    46441 catgaacaag cttgcagaca agagatctgc gcttcctcca ggagagattt ggttttcctg
    46501 acaaaagtgc aacagtgctg taaatggacg atttggtaaa gcactttgac tagcagcatg
    46561 agcaagtttt tgcatttcca ctaacgtttt ctgatcactg cgatgcaata cgcatgtgtc
    46621 atctagcgaa ctcatcaaaa ctaacaacat atgcatttgt ttctgtacat atgaatcatt
    46681 atctagctcc ttagctgctt gaattgcaag cctgatatgc ggatacccta atatcgcttc
    46741 ttcatatgca ccatttacgc catatttttg cttcacccta tgaccatgag tggttttttt
    46801 atgacgatat tttgtatcag gaaaagcagc aagcttgctg acatcatcaa gtattttcga
    46861 taaagaaaaa ggctgttcca tactgatttt ttgtgcaatg acactgatca atagccccat
    46921 tgcccaaatc gctcctttat gggtattgat gccatttgta gcaatcagca ttgccttttc
    46981 cgcttttcgc ccaatctcag caattctttc tcttaactcc tgatcaatag catgatgcca
    47041 tgctatttga gccatttctt caaaaaaagg agttagcgtc ttagcagact taagaaataa
    47101 agcatagtcc atatcggaat gtgcacccgc atccagtgca tccactaatc caggttttgg
    47161 acttaatgtt acttctgcga tcaatgcttc ctctaccaac gcagcgagtt gctgagtcac
    47221 tgcttttttt cgttcgtcat ttatcatgac actcactcct tcttcctact attacttgct
    47281 gaaacctttt ttgatagcta cccaaatgat atgaagtaac cagcttaaag caaatgcaca
    47341 acttgccgtc attagataag ctacaagaat catgactcct gaaggtaact gcagccaact
    47401 atctttaaac aataataaca gtacttggaa aacaaataca ttggctaaat acgtacgata
    47461 agcataaaca gacaaccatt tgaacaatgg caattttggc gaatcgttta caatcatttt
    47521 ggaagcgcct atgaagacag caaagatgat gactaaactg tataaacttt ggatcgtatt
    47581 caagtaaggt gcattcgcaa agctcaagtc tcctggatgt gcgagcaatg aacggacaga
    47641 aaagaacgcg ataactaagg caacaggtaa gaaaagataa cgtactctgt ccaaatattg
    47701 atagactttt tcgtgataaa caaatgcggc taccccataa atcatgaaac tagcaacaaa
    47761 ccgatctaat aagtaccagc tgtcatgata aggcccagtc aatacttgtg tttgatagaa
    47821 cagataccat gcgacatata aaatcgttga accaatcaat actggccata catatttttt
    47881 attagcaaat actttgtaac cgagccaaac aaaaaacggc atgaacaatt ggatctgcag
    47941 catcataacg gtataccata aatgaggcgc tccatcacct gtgacatatt tcagtaaaaa
    48001 gcttgcagta tccgtatacg gagtttgttg ttggactgct ggaaatagcc aaagataagc
    48061 cgtcgtccat agaagatacg gaacgactag ttcaaaaaac ttttctttca aaaattccca
    48121 ataagacaaa tgctgacttg tttttaccat attataaaca attgcaaaaa taaacattgg
    48181 tgctgtgtat ttaacgatga cgtaaaaggt accaagaaaa gctgtatttg ttgcgctgtg
    48241 gctgtttgcc aaagcaaagc tcaatatcgt ttgcatcata acagccgtta cagctgatac
    48301 tttctggaag tcacttacgt tgattttgat ttttttgttt tcaaacatct ctttctctct
    48361 ctttttcttt attaccaaag ttctttggtt aatttaggtc cttcgactgt tttcaataga
    48421 atttttttct ctggctctct caaatactct tttagtgaaa aaccgccttg ccgagtcact
    48481 acttgggtat cgaattgctc aaaaaaagca ggatgcgatt gaattacctg aattggcaat
    48541 tcaatcggtg aatttgcgta cagcagcaaa tcaaaatcac tggtttcttt tactgccgga
    48601 atcccagtcg ataattcaaa tcctaagctg ccgccgattc cccatttaca tcctgataat
    48661 atgtttctag cagcatgaaa ttgctgataa acaggataat ccatgatttt ctcttgtcta
    48721 tacgattctt gttcgatgat gtcccacgga tgaatgactt gtttgacggc atgttttgag
    48781 atttctgttg accatctctg attgcgggca ggtccacgta aaccaatcgg tagtatttct
    48841 gcgtgatccg tcgacgcacg acgaactgtt ccgaacatct tttcagttag aacgacccat
    48901 tcaggcaagg tgaacccttc tatttcatgt ttatcaaaaa ggacaatatc atgtgcttga
    48961 atcatttttt atgcatccca ttcttcgtcc attttggcac ggactttatt tgtttcgaca
    49021 cgtccgaatg ttttggctgt ttcgtttgtg tatcgatttg tcagcatcgt gtcatttgta
    49081 ttgcggacat cttgaatggc ttcattgatt gcttcgatga ctttgctgac attttgttct
    49141 gaagcagctt ggtcggtgat atcttctagg aaatgataga tcgctcctag ttttgtataa
    49201 ttattgatat cgtaagcgat agctggaact ttttcagcag ctgcttcgat ttcagcaacc
    49261 gaacgttttg tcacacgtgc agcactttct ttagacatcg cttggacggt aatttcttta
    49321 ttgtttaaag caatcaagcg gcttgattgt aatccatgtg ctaaaaatgc acctgaaata
    49381 gcatttcctg caatcaatcc aataactgga tgtccagctt gacggagttt tgcataagca
    49441 gcagcactat tagccaaagc cacatggata ccgatcaatt cttcgttata gccgtatgct
    49501 tggcttggta catcgatcac aacgatgatt ggccgtttca cttttttgtc tttatcttct
    49561 tcgtaaacgt gatccaaaat ttgtcccatg cggaaacctt caactaaacc aacttcaccg
    49621 tttcgtacac ggtacatcgg gtttttagga tcaggtacga ttgatgtcac gatggcttct
    49681 tctatgaatt tacttgattt accataatac acagtactaa tagaagaagt tggatttttc
    49741 atgccagtta gtgccgcaaa ccaatcgtaa ccaacacttg ctgcagctgg ttcatttcct
    49801 tctgctactt ctggtaagtc aattgatttt gcttgatggt tagcaattgc ttcattgtaa
    49861 tcgtcaatgg ccattggttt tgaaagatct aaagaatcaa gtaatgataa ataaaatgct
    49921 gagctttcac tgcgatgcgt gtcttttcgt tcgtccattg ctgcgatgac agcagctttg
    49981 attgcttcta cactatcagt cactaattca tcaatgattt ttgattctac ccgttgacga
    50041 gatcctaatg tattccaaat caagtctttg tcactagaat caaattctcg aacgcctgct
    50101 tcttgttcaa taacttctgg tccattcaaa ccgactctcg ctttttttgt tgcgattaaa
    50161 taactcatta atgctgaagt aatcgacata ccgccaaatg atcctacacg tcctggaatc
    50221 aaaccgatga ctggtacata ttgttttaga gcaatgatta catttccgat ttctgaaata
    50281 gataacagtc cgtagtttgc ttcttgcaaa cgaacaccac ctgtatctag tacaatgact
    50341 ggaaagatct catttccttt tttattttct tctaacacat gttcaagtgc agcaacgatt
    50401 tttgcaccgg aaacttcacc gataccgcca ccttggaatt ttccttccat agcgattact
    50461 actgcttgtt tgccattgat cgtgccacgg ctgacaacga tcccgtcatc actttcaggg
    50521 acgattcctt gtgctggtaa acttggcgcg atgatttgat cgaatggatc aatcaattca
    50581 cgtccattgt caagtagagc gttcactcgt tctctggcgt ttaattctac aaaactattt
    50641 ttcatctgaa agttcctcca ttgcttgcgt caatcgtagg tacacaactc ctggtgtagc
    50701 accgaagtca ttgatcacga tatctgctga aattggataa cgatcaaaaa atctcgttaa
    50761 tacattgttc catacttcgc cgaagccatc gcttcctgta caaattttta cagtagattc
    50821 tgttttttct gttggaaaca tcaagatttc caaatctcct gaaccgacca ctcctacatg
    50881 gattttctta ttgatcggct gtttcgttgg atatttataa gctaattgtt ccatggatct
    50941 ctcccctttt tgtaaaacag agcatacacg ttctgcttat tcgtctttct tcttccatct
    51001 gggtaaatgg cgacaaaagg tttttctcgc caattttatg accaagttct gaatttcatt
    51061 ggtggttcat acaggccatc tgaccattcg atcaaatcat cgatggtttg tgcagctaat
    51121 aatgaacgtt tcgcttcact acgtttgatg cctagatctt ctggtaattt cacgatgccg
    51181 gctgcacgca agctatctag tgattctttc gtgctagtca ttccaagagg tgtaacaccg
    51241 ccaattgctg caattgctgc ttgtcgttct tcttttgttt ttgctttgta caaataagca
    51301 attccttctt ctgtcacgat atgtgtagta tcttcgctat aaatcatcac tggtgcattg
    51361 gctaagcctg cttgtttttg aacagctagt gcatctaatt cttcgacaaa gactggtttt
    51421 ttatttgaac catatgtttc aaccatttga acaactaatt tttggccttt ccctaatgga
    51481 tcatcattgt cgcgaagtga ttgccatgct ggtgtagaat gacgacgacc gccaggatta
    51541 tgtcccatgt taggcgcacc gccaaaacca gataaacgtc cttttgttac ggtagaagag
    51601 tttccttcgt aatctaattg caaggttgaa ccgataaaca tatcgatggc atattgtcct
    51661 gcagcttgtg ataatgttcg gttactgcgc atcgtgccgt ctttaccgac aaaaaagaca
    51721 tctgggcgag cagcaatata tttttccata ccaacttcgc caccaaaact atggatgctt
    51781 tcaacccaac ctgattcgat ggctggaatc atcgttggat gtgggttcaa tacccagttc
    51841 ttcgcgattt tcccttttaa ccctagtgat tcaccataag ttggcagtaa caattcgata
    51901 gctgctgtat tgaatccaat accgtgattc aaagattgta cgccgtgttc tgcgtagatt
    51961 cctttgattg ccatcattgc cattagaatt tgcaattctg tgatgttttg aggatctcgt
    52021 gtgaataaag cttctaattg ataaggttta tctgctttca cgacaacgtc tacccagtca
    52081 ccagggatat ctacacgtgg taaagaatcg acaacttcgt taacttgaac gatcacgata
    52141 ccatctttga aagctgcagc ttcgatgatt gttggtgttt cttccgtatt gaaacctgtg
    52201 tacaagttgc cgtctttatc tgctttatct gcagctacta aaacaacatt tggaatcaaa
    52261 tcgatgaata agcgtccata aagttccaaa taagtatgga tatcacctaa tttcattgtg
    52321 ccgtcttcaa tcatttgggc gacacgcaag ctttgtgcac cagcataaga gaaatcgatc
    52381 ttgcttgcga ttcctttttc aaaaatattc aaatgttctg gtcgtgagat actagacatg
    52441 atcaaatgca gatcattcac tttttctgca tctacttttt caagactttc tgaaagaaaa
    52501 cttgcttgtt tttgattgtc gccttctaat acaactttgt cgccgggagc aatcagtttt
    52561 tccattactt ctacgatttt ttcagtttct acatacttgc cattgagcaa gttgctgatt
    52621 ttttccaatc gctgcgcttt tttttcgcgt ttagaagccc agttgcggtt tggtttttcc
    52681 ataattagtc atctccattt ttgatataga aacgtggcgt catcaatacc atgttggtct
    52741 agattgatcg tacggatccc tttatctaca ccaaattttg tatgaatcag ctttgtcaaa
    52801 gtattgccgg ggggaaattc aatcgtcaga tccattccta attcttttgc caagtccatc
    52861 atttggttcc actgcacagg gaaagctagg ttttccaaca aatctttacg aatctcttct
    52921 gcgtcctgag tggctcttcc atccgtattt tttatataca aacatctagc atcagataga
    52981 tggacagact gcatatacgg cttgaatttc ttgaccgtat cattcatcaa gagacagtga
    53041 gatggcacag ggactttcag cagcttcgct gtttgcgctt ggtgccgttt ggcttctgcc
    53101 aacgtaacgg ataaaccttc gatactccca gataacgtat gttgcatcgg acaattttca
    53161 tttgacagat aaactggatg gtcaggatca aatgtttttg ctacaatttc ctcagcttcg
    53221 cttctcgtca cacctactac tacgcccatt gcataaccgc ttggataagc ttctttcatt
    53281 aagactgcgc ggtgatagac tagttccgct gcattctcaa atctcaaaga tcgacaagca
    53341 acagctgcac aaaaagcacc aatcgaatgt cctgctgcaa tatcaggctg aataccgttt
    53401 ttttccattt catctaaata aaatactgct tttgtcagta atgctagctg gataaaaacc
    53461 gtatcttgat agttttcttc tttatcaact aaccgatacc ccgtcacatt ttctaaacgt
    53521 tccatgtaca tttcagggat atccgctaac atccctaact tctgactgcc ttgtccagga
    53581 aataagaaac ctgtactcat gagcctcgcc tcctcagcac ttactttttc cactgctatc
    53641 ttagtcaatt tctgctataa taaaaaatgc caaaaaaaga aaaaaccata acaaaaaggt
    53701 atggatggga tggataatta tgaaattgct tcatctgcag tattttaaaa aagtattcga
    53761 aacaaaaaat gttacccaag cagccaaaga attatttatt tctcaacctg ccttgagccg
    53821 tgcgatcaaa catttggaaa acgaattagg tgtccctttg ttttaccata gcggcagaaa
    53881 cattgagacg accgtttatg cagaagaatt ttatccatat gcagtcaaga cattagacac
    53941 attagaagaa ggaatcaaat tattgtcttc ggtcaatgag aagatcgtta cttccgtcat
    54001 attgtattta gaggtagcct ctgtttctat tccgaacttg gtccgaattt ttatggaaaa
    54061 gcatcctgat atccaattaa cgatcatgca acatcattta ccagatgata ttaccgatcc
    54121 tgtactgtac atcacttcgg agatgaagcc tggcatgacc aatattccta tcatgaaaga
    54181 acctgtttat gtcgccattc ctaagaaaca tcctcttgct aaaaaagaac atctgcaatt
    54241 agaagatatc caacgcaccc ccatcttgat gctgtcaaag agcaacgcct tccgtcatac
    54301 actggatgca gcacttgaag cgaaaagtat cgaattgacg atcagttcga cgacagatga
    54361 tcctgcgaca ttacgttcta ttgtcaagca aggattagct gttagctttt tcccaaaagt
    54421 ttcttggtct tacgataaaa atgatccttt cgtcttgcgg gaaatcaaag atttgccctt
    54481 gacacgaaca atttatttat cttctagctt cacagaagat catcctttga tcaaaatgat
    54541 tgcaaaaacg atgcgggaat tttatttagg aaaataaaaa aaaaagagct gggacaaaat
    54601 tcttgtcgca gctctttttt cgaacaaacg gtgttccaga agtaatttct tagaaaataa
    54661 gccgaaattt cccaaaaatt tgagaagcaa ttttcgtaaa ttccttctta tttcttgaag
    54721 ctaaacattt ctgtcacaac ctcttctcta ttgtcctaga cattcattgc gttgatttaa
    54781 aacttccatc aatcaaatct gctagttcat ctagcttttc tattttacgt agatcaatag
    54841 agatccaatg ttctttattc atgtgatagg ctggaaaata cccctctttt cctcgcaaaa
    54901 ttccgccaag ttcaggatcg accttcaaat caagaatatt gatgatccta tggtcacttg
    54961 catcatcata gattttttct tctggaacag acatcaggac cccaaaccat tttttgcttt
    55021 tttgatgtct gaatacgcaa taatcaggaa attttttaaa aatatattct ggagacaaat
    55081 tgtatgtttc attgatgtga tcgattagtt cttttttcgt tagcatctgc ttccatctct
    55141 ttcttattga ttcgctttat tcaaagatac cacgtaagaa tagaaaaatg aatacaagta
    55201 gttgctaatc aaatacttcg atatttttct tttttatcaa ctcttaaatg ttcaatccgc
    55261 ctgtgttggt cttgctacca tctactatta aaatgtttat tattgtttgc ccacctattt
    55321 tttgatttta gtggtatcat ttttcaagtt catgatgaaa ttcttatcat cagtaaatgc
    55381 tccagaaaaa taaacaatga ttgaaaaatc agttgaaact tgaccaccgt ttattttctc
    55441 cgtattctta gaatagaagg gagtctgatt gatgtattca ctaatgaaaa aaatcattac
    55501 cgaaaaagat attcgacgtc atgtttcttt agtagaacaa ttgctgaatc atacaaagat
    55561 aaccgtaaat gaattagctg aaatcatagg gacaaccgaa cgaacgattt tttctgacct
    55621 tcaatctatt cgctctcagc tgcccgaagg ctgggacatc atcagcgatc aagcaggaat
    55681 cagtttgcaa aaccagcaaa atttattaac aaatgacctt tgggagattt ttttcaaaca
    55741 atcagtcagt gtcgaactgc tgaaaaatct gctttttaca aaaaaagttg ctgtccctga
    55801 ttttctagcc gaccatgggc tttcttatgg gacattgaaa agacatgtga ctaaaatcaa
    55861 tcagcgttta gcaagttacg acttgcagat cgatttgacg aaatatacag cttgtattct
    55921 tggaaaagag cgtgcgattc gtacttttta tcatcgattg ctgattcctt tcactcataa
    55981 caactatttt ttcgaggatt attcgatcca tgaatcccat tattttcaat ttttaagaaa
    56041 cctcagtcaa actgaactag cggttgaaac agaagagatt ttcggaacat gttggttctt
    56101 tatcaatacg atccgtataa aagcgaattg ccgattagat tcttctatcc ataccaacag
    56161 cacactctcc tccctgtatg actctgcatt gaaaaaattg tatttaacgg aaggtattta
    56221 tcttaaagac actgagcttt cttttgcttc tttctgcttt ctggaaagtt ggaattacaa
    56281 caataactat ggacaagaaa ccgctcgctg cctgcatcat tctccatttt tagaggtcct
    56341 cgaaacgttt gtagaggaac tagcttcaga gctgtctctt gatcaactaa aaaaaacatc
    56401 tctgactgat aacttggctc tcctcatatt aaaatatcat gaatcgccga tattgattga
    56461 agcattggac cgtcaatacc atcgtttttt agaaacatat gatcagcaat atgcacactt
    56521 gtatcaacag aaagagaatt tactgaacga tctaaaaaaa gaaatagaaa tcaatgaacc
    56581 aaattacttt ctccaactct tgtctctact gatccaacaa acgatttttt ctatcaaacc
    56641 gaatttgttc aatgtctatt ttattttcca aggagaacct tcatggaagg cgttcttgca
    56701 gcaggaatta aaagattact taggaaaacg tgtctgcttc ttacctatcg aactaaccga
    56761 tctttccact atttcttttg aaaaaacaga tatcttgatt tccaatttcc ctctagattc
    56821 tctagatatc cctattgtat acatttcttc tattccaacg aaaaatgagc tcaatcgttt
    56881 gactgaactc actttcaaaa cttttttata gtaacggcta gcgactgtat tctctagctg
    56941 ttttttcttt tttgcgaaac agtttgttca tgatcccttt ttctatttct acaactaaga
    57001 atagaagaat cacatttgct ccaatcaata actgttgtgt catcgttaaa cttactgtac
    57061 cgatcagctg ctggccgact ggtagaaaaa taaccatccc ttgcaataaa gcaaggatac
    57121 ctaatgaaag aaaaagcgct ttgttttgca aaagaccttg gttcaatgac ggcttggaca
    57181 actctctgca attgatcatg taaacagctt gagctaagac gatattttgc agaagaatgg
    57241 tttgctgtaa gctttgccct tcaaactgca tagccaataa ataggcagga accatgatca
    57301 gtagggagac atagatgatc cgaaacaaat gataaccaga taggattcct tgctttggat
    57361 ctcttggtgg gcgcttcatg atttctggat ctggcgactc gaaccctagt gcataagata
    57421 aagtgattgt cgttaccata ttgacccata aaatctgtac tggggacaaa ggtagcgggc
    57481 gattcagcat aagtgcccaa atcaagatca atccttgagc taatgcagtt ggcaagaaga
    57541 aattgatggt tttttgcaaa ttatccaaaa tccgccggcc ctcttttacg gcttttgcaa
    57601 tcgtatggaa attatcatct cctaaaacca tatcagctgc ctgtttgctt acttcactac
    57661 ctttgattcc catagcaatt cctacatcgg atcttttcaa agcaggtgca tcatttacgc
    57721 cgtctccggt cattccgacg atttctccat ttttctgcaa agctttaaca attcgcagtt
    57781 tatgttctgg tgtcgttcga gcaaagacat cgactattgg cacttgctga atcaactctt
    57841 catcagacat aagatccaaa tcgatccctt ctaaaacttt ggcagtatgt tttaagccaa
    57901 tttgttccgc aatcgctttt gctgtgtctt tgtgatcccc tgtaatcatt ttcactgaga
    57961 tccctgcttg ttggcattcc tttacagctt tgactgcact ttcttttggc ggatcgatca
    58021 atccggcgat ccctgcaaaa gttaattggg ttaaagtctc atgcgtgagt tcctgtttcg
    58081 aatctacttt tttataagca aatcctaaaa cacgctgacc ttttctcgca aattctgcag
    58141 ctgtctgact ccatgcttct tgttctgcag aagaaagagt tgatttagca aataatactt
    58201 ctggtgcacc tttgacgtaa atcaccgctc ctttttcctc cgcatgcatc gttgccatat
    58261 atttgtattc agaactgaac ggaatctttg cttctatttt tttcaaaggt agattggctg
    58321 tttctgtgtg tcgaatcagc gcaacttctg tcggattgcc acttaaattt tctgttttct
    58381 gttcttcttt tgtttttaat tcctgacagt ttttcataat ggacaacacg caggcttctt
    58441 cttttgcagc tacatccaca actgtcattt cattttttgt caatgttcct gtcttatctg
    58501 aacagatcac tgtcatagaa cctaatgttt ctaccgaagg aagtcctttg atgatcgcct
    58561 tttcttttgc catttcatgt actccaacgg atagaatcat ggtcaaaaca gctggcaatc
    58621 cttcgggtac cattgacacc accaaagcaa tcgtagccga aagaagaata tgccaatcca
    58681 taccatatcg aaatgtcgta aaaataacta agaataggct caaacaaaga atgccttgaa
    58741 aaatttgttt gtttaatcgg ttgatttttt taatcagagg cgtcgtttgt tgttcgaccg
    58801 attgcaatgc ttgattgatt ttaccgattt ctgtcgtgtt tcctgtttct acaacgacac
    58861 cgactgcaga accagattgt acaagcgttc ctgaaaaacc catatttttc tggtcgccga
    58921 tcgattcttc ttctgtcaaa acggcatgac ttttttcaga tgcttctgat tctcccgtca
    58981 aaatcgattc ttccactaat aaatcatgtg cttcgattaa tcggatatct gctggaacga
    59041 catctccggc acgtaagaca atgacatctc cttttaccag ttctttcgca gggatttttt
    59101 cttgcatccc gtttgatagt actatcgctt cttgtcccat cagctgcttc aaaccattca
    59161 atgattcttc cgcttttctt tcttgccagt aactaacgag tccattgacg atcactacga
    59221 ataaaataat acttccttca atatattcac tagaagcaaa tttcaaaaaa gaggcaatga
    59281 tcaacacgat catcagcaga tcagtaaaat gctttgctat ttttttccat cgttttgtct
    59341 gctgccttgc ttttatttca ttatatcctt gatcagtcag gcgtttctgt cgttcttctt
    59401 gcgacaagcc ttctgttgat gtttgatagt ttttcaatac atcttctacc gtcaatctgt
    59461 accagttcat cctatcccct cctgtttaat tgatactgtt attatacgca gggaagtttt
    59521 ttcaggcgta tcgattattt caggggggtc tgaaataatt cgttttgcaa aatgtatctg
    59581 ggcctaactg atatttctat tgcttattct tttatataca aaatttaaga atacaaacca
    59641 gataaccaat aaaaaaggaa taaagcgtgt cgtgctttcg aataacaagc tgaaagcaat
    59701 tgaagtaaaa aacaccaaca aagcaagatc tttatatctt tgtgtagtgt tccgtttctt
    59761 ttctttaata aattgaacat gtgcacacaa gatcgaagac cacacaaata gaaaacaact
    59821 cgttgtcatg cctgccaaaa gctgaaaaaa caatcgacta tcagctacaa aaaaatgtag
    59881 acaaagaccg gcaaaaaata acattcctgt aattaaaata ccgtgtaaag gtacgccttt
    59941 cttagaaagc gcacaaaacc aatggggcaa acttttttct tttgctgttt gatataaaat
    60001 cctgctagta ctgtagactg cactatttgc tgaggacaaa gaagcaacca aaatcattag
    60061 attgacaatt gctgctccgc cttggcaatg gatcacttgc agcatagtca ctaaaggact
    60121 ttcttttaaa tctaaacaat gccatggaac aacaaataaa atcgacaaaa tcgttcctat
    60181 atagaaaaag agaatacgcc aaggcagaca gttgattgct tttttcaaat tcttttgcgg
    60241 atcacttgtc tcgccaacgg ttaagccgat catttcaatt ccagcaaaac tgaataaaac
    60301 cataggaaat gagactacca ttccagcaaa gccaaacggt agtaattcat cgatctgtcc
    60361 aaaattttct ttgattccga tagactgggt atgaaaatct gagacactca atcctatacc
    60421 caataagata aaaaggaaaa tccccaagat cttgatgatt gagaaaaaag attccaattc
    60481 accaaaccac ttgactgcaa caaggttgac tgccattaag atcattagtg cgctacctcc
    60541 gcttatcaaa gctggtacat gtacaaacca gaaatggata tacaatccta ttgctgttaa
    60601 ttccgcaagt ccagctccaa gccagcaaag ccaataagtc caattgacaa aaaatgccca
    60661 ctttttgcct aaataatagt caacgaaatc actgatagag ttaaatgtac tatttgctaa
    60721 aaataaatca cccatggccc gcatcaaacc ataaatagcc aaaccgcata tcaaataaac
    60781 gagaataaca gctggccctg ctgatgcaat tgcctttgct gaacctaaaa ataatcctgt
    60841 tccaattgcg ccacctaatg cgattaactg gatatttcga ttagttagag tccgtttcat
    60901 tgccggtttt tccatcaagt tcaccttttt ctttttcaag cagcatggcg acttcctgtt
    60961 cccaagaagg tttctttatt ttttcaatac agagtggtac tacaaacaaa atgacactga
    61021 tggctgtgac tgcaattaga ttgatccatg ttccagcttt catcgtcagt ccgacagaaa
    61081 atccgattgc cgcaaataaa acaataacga cagtccaaac tccaagattg ctctttttct
    61141 ctttttttcc aattctaaat ggtcgattca actttgcatg tgtataacgc aatctcaaaa
    61201 ctgcgatccc catgatgaca tagacgatac agtagataac agtagttgaa tttacgagca
    61261 tcaaaaatgc ttgattgacg ccaggaatca gcaaataaaa aagtgcaaag attgagataa
    61321 tgacagactg agtcaaaata acggatttgg atacgtcaaa ttgattcgtc ttccaaaaat
    61381 tgaattttgg tggatacgca ccttttctag cactttctgt cactgtcttt gctggtcctg
    61441 aggcccaagc agataattgg actgctacac caatgaagac aagtaaacta aacagattca
    61501 caataagatg tggcaaacca agaatttggc aataaatcga aatagattgc gcgatattat
    61561 tcaattccat ttgtcctttt ggtacgacat ttgctacaac taaagcattc aaaatattga
    61621 cgaaaaatat aaaaattaac gcggcaaata ctccgcgaat atacgtttta actggatttt
    61681 ccaatcgagt gatatacaca gaggacattt cgataccagt aaaaataaac atgatcggcg
    61741 caaaataaac aaatgaggat gcagtcgtag tatctggtat taatttgtcc catgaaaaac
    61801 tgcctaatgt tccggttggt acgatcccaa ctttgatcca cgcagcaaac cctaataaga
    61861 gcatcatcgt caaaggcacg tacaatccta accaaacacc gacttttccg ccgatttttg
    61921 ccatatcaaa tttcaaattc aaaaaagtga tgatccaata aacgactaaa atgacaacta
    61981 atgtaaattt gctgttcaaa ccaagcggca cattatcgat aatattacca aacaacggag
    62041 cgagtgctga agcgaccatc accatcccag gaaacatttg gacccataac agccatgaga
    62101 caacgaaccc ccattttttt cctagagcat tcgataccca aagttctgga ccaccttttt
    62161 ggggaaacat tccagcaaat tcaccagaga tcaatgagat tggaaaagcg tacaataata
    62221 ctgcaaccag catgtaaaaa atcatcgtcc agctcgttgc tgctacatct ggaatatttc
    62281 gtacacttgc tacaagggcg caggtcattc cgataaaggt catggtcgtg atttgctttg
    62341 atgaaccagt atctttcatc tttattcctt ctttcaatag cgacatatgt ttttgttttc
    62401 ttttattttt gttcaagaac agaaatgaca aggtttcatc gattcagtac aaaacccagt
    62461 atcaccgaaa catccattga acgatcttag tgaactgggt ttgatacatg aaacgaacga
    62521 tccaacttat agaacgtttt ataaaaaaga atatcttggc gaggaatata tgaaaaacag
    62581 ggggaaatac aattgttttg atgaagcaaa taattgtctg ttctccatat gtctcttgtt
    62641 attctttcac acaaaaatca gttctattgg atgatttcgt ttagtttctt ttccattgct
    62701 ttggcgattt tttttgtata aaaattgaaa attcgatcat cattcaaata aggagtcatg
    62761 atagccgcac gtagcagagt gattttctgt tcttttttcc attcttcttt cgttagaccc
    62821 attctttcaa caaaacgaat cggagaatca ccgtaatctt cttgtgtaaa tgtagtatga
    62881 gaagtaataa accgttcacc ataaacatcg ccatccatat aagaagaccg atcgaacatt
    62941 ttttcattta attcattgat agcgttcaaa tctgtacagc cttgttcttt gaatacccaa
    63001 ttgaccatat taaaatcagg atgattcaat ggatagactt cgattgtttt tcctttaaca
    63061 gtaaaagtca gatgatcgag aaattctctg aatctttgag ctgcctcgat tgaagcccca
    63121 atcaattgac catatccggt cacattcaat ggcaatacac gatgtgctgt ccagactgcg
    63181 gcggcggttg ctccagcttt tgatccttcc aaaatataag ctcctaacat atctggagcc
    63241 tttactgatt tttcaaacac atatggcgcg aaataagaaa tgatatttct catattttta
    63301 tgtttgatta cgattcctcc agcagcataa gggacatagc ccatcttatg aggatctatc
    63361 gtgacagaat ccgcttctga aatagctctg aacccttcat atacctcttt gtcaatcgtt
    63421 acgcagtggt ggaaaacatg atgttcttca aagaattcag ctaaggaagc atacggcaca
    63481 aattctcctg cttcgtttag aaacagtgaa cgcgcatagc cgccatatgc ggcatcaaca
    63541 tgtaaataga aatagatccc ttcatctttt aacctttctc ttaattggac gattttatct
    63601 acactgtcta cttgaccttc ttctgtcgtt cctacgacag caaccacacc tagaattggg
    63661 attttttgtc cagctaattc acgaattgtt ttttccaaag cattaatatc cattcgataa
    63721 tcctcttgaa ctgggatagc aaccatctga tctaagccga ctccgcaaat atctaacgcc
    63781 ttcatccaag aatagtgttt tgtttgaggg accagccatt tccctaatct ttggatattt
    63841 tttccgctac gggaagaagc tgctttgacc tcatccattt cttcgtccgt aaagctttcg
    63901 gtcatttcca aaatttcttc aacagataaa ttcaaaagtt cccactcaga catttttttc
    63961 actttttcag gcagcacttc cttgacagct aaaggaatcg atttgatgca acgggcgtac
    64021 cataatcctt caagattagc aatagaacca tctgctgcaa tgtgtcccca tccgtctgtc
    64081 atattgaata atgaagcaaa atcctgtcct acttctgctt ccatttgcga agttgccata
    64141 gaagattcca atgcaacatt atttgggttc cacagcatcg catagttgta agctaataaa
    64201 gcaggcatca atgtttcagc attcatttgt ccccagtaac ggcctgctga atgccatggg
    64261 atcgatcctg cgcgtaatcg ctgactgact tcatccaaga cctctatcat atggtcgcgg
    64321 gtggctagat aatctggagt gagcttatct ccttcgctaa ttgcaggcat atctgaagga
    64381 atataatttt ctctccatcc aagatgttca tctaccatct tgttcaacaa cattttataa
    64441 actggtccat tttcagcttt gtcgcctata aagacggcct tgatatccat atctttcatt
    64501 tttcttccct ccatattttg ttggtcaatg tcttgcagat acatgtgttt atctgtaaca
    64561 cctcttcact atagcgccaa aaatgagaat ttttttttta taacatcaaa tccacgtaga
    64621 tttttacaaa caaaaataaa taaagtcgga tttttctgat aattcaacgc aaaaaagcga
    64681 acaatttttc aataaatcag tcttctaaaa tagataacct aaaaaaagcg aacaaacaaa
    64741 taaaatgact gtccttcatt ca
//
LOCUS       DAFLWQ010000005        61717 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.005, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000005 DAFLWQ010000000
VERSION     DAFLWQ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61717
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.005"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            25..696
                     /locus_tag="L1V16_000317"
     CDS             25..696
                     /locus_tag="L1V16_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBN1274685.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            755..1195
                     /locus_tag="L1V16_000318"
     CDS             755..1195
                     /locus_tag="L1V16_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274686.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1207..1875
                     /locus_tag="L1V16_000319"
     CDS             1207..1875
                     /locus_tag="L1V16_000319"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBN1274687.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1939..2562
                     /locus_tag="L1V16_000320"
     CDS             1939..2562
                     /locus_tag="L1V16_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBN1274688.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2618..3004
                     /locus_tag="L1V16_000321"
     CDS             2618..3004
                     /locus_tag="L1V16_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HBN1274689.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3217..4608
                     /locus_tag="L1V16_000322"
     CDS             3217..4608
                     /locus_tag="L1V16_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HBN1274690.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            5219..5587
                     /locus_tag="L1V16_000323"
     CDS             5219..5587
                     /locus_tag="L1V16_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HBN1274691.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            5767..6708
                     /locus_tag="L1V16_000324"
     CDS             5767..6708
                     /locus_tag="L1V16_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBN1274692.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            6777..7508
                     /locus_tag="L1V16_000325"
     CDS             6777..7508
                     /locus_tag="L1V16_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBN1274693.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            7652..9832
                     /locus_tag="L1V16_000326"
     CDS             7652..9832
                     /locus_tag="L1V16_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBN1274694.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            9852..10334
                     /locus_tag="L1V16_000327"
     CDS             9852..10334
                     /locus_tag="L1V16_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HBN1274695.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            10350..11111
                     /locus_tag="L1V16_000328"
     CDS             10350..11111
                     /locus_tag="L1V16_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBN1274696.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            11242..12576
                     /locus_tag="L1V16_000329"
     CDS             11242..12576
                     /locus_tag="L1V16_000329"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBN1274697.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            12883..13368
                     /locus_tag="L1V16_000330"
     CDS             12883..13368
                     /locus_tag="L1V16_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HBN1274698.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            13361..14044
                     /locus_tag="L1V16_000331"
     CDS             13361..14044
                     /locus_tag="L1V16_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBN1274699.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGIILAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            14170..16815
                     /gene="polA"
                     /locus_tag="L1V16_000332"
     CDS             14170..16815
                     /gene="polA"
                     /locus_tag="L1V16_000332"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBN1274700.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            16860..17696
                     /gene="mutM"
                     /locus_tag="L1V16_000333"
     CDS             16860..17696
                     /gene="mutM"
                     /locus_tag="L1V16_000333"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HBN1274701.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            17660..18289
                     /locus_tag="L1V16_000334"
     CDS             17660..18289
                     /locus_tag="L1V16_000334"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBN1274702.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            18341..18673
                     /locus_tag="L1V16_000335"
     CDS             18341..18673
                     /locus_tag="L1V16_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBN1274703.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            18985..19476
                     /gene="nrdR"
                     /locus_tag="L1V16_000336"
     CDS             18985..19476
                     /gene="nrdR"
                     /locus_tag="L1V16_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBN1274704.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            19499..20872
                     /locus_tag="L1V16_000337"
     CDS             19499..20872
                     /locus_tag="L1V16_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBN1274705.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            20872..21798
                     /gene="dnaI"
                     /locus_tag="L1V16_000338"
     CDS             20872..21798
                     /gene="dnaI"
                     /locus_tag="L1V16_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HBN1274706.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            21927..22367
                     /locus_tag="L1V16_000339"
     CDS             21927..22367
                     /locus_tag="L1V16_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBN1274707.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            22511..23212
                     /locus_tag="L1V16_000340"
     CDS             22511..23212
                     /locus_tag="L1V16_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HBN1274708.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            23209..24330
                     /locus_tag="L1V16_000341"
     CDS             23209..24330
                     /locus_tag="L1V16_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBN1274709.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            24345..25577
                     /gene="pepT"
                     /locus_tag="L1V16_000342"
     CDS             24345..25577
                     /gene="pepT"
                     /locus_tag="L1V16_000342"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBN1274710.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            25709..26617
                     /locus_tag="L1V16_000343"
     CDS             25709..26617
                     /locus_tag="L1V16_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBN1274711.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            26652..26924
                     /locus_tag="L1V16_000344"
     CDS             26652..26924
                     /locus_tag="L1V16_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBN1274712.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            26935..27981
                     /locus_tag="L1V16_000345"
     CDS             26935..27981
                     /locus_tag="L1V16_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBN1274713.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            28232..30841
                     /gene="clpB"
                     /locus_tag="L1V16_000346"
     CDS             28232..30841
                     /gene="clpB"
                     /locus_tag="L1V16_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBN1274714.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(30992..31678)
                     /locus_tag="L1V16_000347"
     CDS             complement(30992..31678)
                     /locus_tag="L1V16_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274715.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(31656..32150)
                     /locus_tag="L1V16_000348"
     CDS             complement(31656..32150)
                     /locus_tag="L1V16_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBN1274716.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(32170..33390)
                     /locus_tag="L1V16_000349"
     CDS             complement(32170..33390)
                     /locus_tag="L1V16_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1274717.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            33537..35372
                     /gene="lepA"
                     /locus_tag="L1V16_000350"
     CDS             33537..35372
                     /gene="lepA"
                     /locus_tag="L1V16_000350"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBN1274718.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            35568..36479
                     /locus_tag="L1V16_000351"
     CDS             35568..36479
                     /locus_tag="L1V16_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1274719.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            37475..37726
                     /locus_tag="L1V16_000352"
     CDS             37475..37726
                     /locus_tag="L1V16_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274720.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            37809..38081
                     /locus_tag="L1V16_000353"
     CDS             37809..38081
                     /locus_tag="L1V16_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274721.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            38171..38410
                     /locus_tag="L1V16_000354"
     CDS             38171..38410
                     /locus_tag="L1V16_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274722.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            38557..42840
                     /locus_tag="L1V16_000355"
     CDS             38557..42840
                     /locus_tag="L1V16_000355"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HBN1274723.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            42939..43304
                     /locus_tag="L1V16_000356"
     CDS             42939..43304
                     /locus_tag="L1V16_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274724.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            43306..43758
                     /locus_tag="L1V16_000357"
     CDS             43306..43758
                     /locus_tag="L1V16_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274725.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            44372..45682
                     /locus_tag="L1V16_000358"
     CDS             44372..45682
                     /locus_tag="L1V16_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HBN1274726.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            45705..46016
                     /locus_tag="L1V16_000359"
     CDS             45705..46016
                     /locus_tag="L1V16_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274727.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            46377..47633
                     /locus_tag="L1V16_000360"
     CDS             46377..47633
                     /locus_tag="L1V16_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBN1274728.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            47630..48175
                     /locus_tag="L1V16_000361"
     CDS             47630..48175
                     /locus_tag="L1V16_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274729.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            48176..48676
                     /locus_tag="L1V16_000362"
     CDS             48176..48676
                     /locus_tag="L1V16_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274730.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            48757..49313
                     /locus_tag="L1V16_000363"
                     /pseudo
     CDS             48757..49313
                     /locus_tag="L1V16_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            49333..49677
                     /locus_tag="L1V16_000364"
     CDS             49333..49677
                     /locus_tag="L1V16_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274731.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            49696..50607
                     /locus_tag="L1V16_000365"
     CDS             49696..50607
                     /locus_tag="L1V16_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1274732.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            50686..51678
                     /locus_tag="L1V16_000366"
     CDS             50686..51678
                     /locus_tag="L1V16_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBN1274733.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            51675..51893
                     /locus_tag="L1V16_000367"
     CDS             51675..51893
                     /locus_tag="L1V16_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274734.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            51906..52316
                     /locus_tag="L1V16_000368"
     CDS             51906..52316
                     /locus_tag="L1V16_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274735.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            52368..54896
                     /locus_tag="L1V16_000369"
     CDS             52368..54896
                     /locus_tag="L1V16_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1274736.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            54912..57122
                     /locus_tag="L1V16_000370"
     CDS             54912..57122
                     /locus_tag="L1V16_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274737.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            57130..58221
                     /locus_tag="L1V16_000371"
     CDS             57130..58221
                     /locus_tag="L1V16_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBN1274738.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            58242..58784
                     /locus_tag="L1V16_000372"
     CDS             58242..58784
                     /locus_tag="L1V16_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274739.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            58979..59236
                     /locus_tag="L1V16_000373"
     CDS             58979..59236
                     /locus_tag="L1V16_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274740.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            59250..59582
                     /locus_tag="L1V16_000374"
     CDS             59250..59582
                     /locus_tag="L1V16_000374"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274741.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            59627..60175
                     /locus_tag="L1V16_000375"
     CDS             59627..60175
                     /locus_tag="L1V16_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBN1274742.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            60182..60634
                     /locus_tag="L1V16_000376"
     CDS             60182..60634
                     /locus_tag="L1V16_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274743.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            60731..61066
                     /locus_tag="L1V16_000377"
                     /pseudo
     CDS             60731..61066
                     /locus_tag="L1V16_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT        20979 a         9989 c        13198 g        17551 t
ORIGIN      
        1 aatgatgaaa aaagggggag aaaaatgaat tttttagttg ttttaaaaga tactctgatt
       61 gagcgatcta catttctata tgttcaattg caggaaaata aaacattgct gcatttttca
      121 ccagagttcc atctagaggg gctaacatta ggagaaatct atcaagcaga agggctgtcg
      181 gctgttttgc acttttttaa ggtagaattg gaattaccag taaaagatta tatcgagctt
      241 tctcttgaat cttgggatcg agcagtggtt gaactgtttc cagaaggttt aatgatcgat
      301 acaaacgatg ggaagatcca tctgactgca gcagaactgc aaaaacaaat gcgttatcaa
      361 atagatgacg aaaattcttt ttctattttt agacgtcagc aaaagattct aaaaagcttt
      421 ttaaaagtga tcagtaaaaa acggaatctg atcaaaacga cacagctgtt gaaaaaatat
      481 ccaggtctgc ttcacacgtc tattcaattt cctcaattga ttacgatgat ccatcgtttt
      541 atacgtatgc aacagctacc atctaagaag ctgtttcttc cattgacgga cacatttcga
      601 gtagtcaaca gagaagataa aaagaaagtg attgtgattg actttaccag aaatcggaat
      661 gtccttcacc aagttgcaat ggaaaaggcc aattaaggct ttttcttttt ggattttttt
      721 gtcataataa atattagatg atggaggaga taatatgatg caaacatggt tagaaaggct
      781 aatacgattt cagcagaact atcacaaact tatgcaggga agatatgcga aatttgatca
      841 gttgaatcgc ggtctattga tcgctgcgct tgtctttagt ttgctaagtc gttggttgcc
      901 ctatagaatc ggacaattgt tgttcatcgt ctttttcgga tggatgatat ttcgtttcct
      961 atcaaaaaaa atctacccca gactaaatga gaatcaacgt tatttgaaat atcttgatag
     1021 agtcaaagaa aaatatcatc agataaaaaa caaaaagcaa gtcaaaatgg atcgaaaaag
     1081 ttatactttt tttgagtgcc cgaattgtca tcaaaagcag cgtgcaccta aaggaaaagg
     1141 acgaatacgt gtgacatgca aaacatgtgg tataaaattc gaaacgaatg tttaagggag
     1201 aaaagaatga aattagtatt attacgtcat ggcgaaagcg aagcaaattt tgaaaattac
     1261 tggacaggat ggctagatgt cgccttaaca gaaaaaggaa aagaacaagc agcagttgcc
     1321 ggtcaaaaaa tgcttgaagc cggacttcaa ttcgatgccg tttatacctc tgttttgaaa
     1381 cgtgcgattc ttaccggaca agtcgcacta gaagaaatgg gtcagttatg gcttcctata
     1441 ataaaaacat ggcgtctaaa tgaacggcat tatggggatc ttgtgggtaa aaacaaagat
     1501 aagatgaaag aaatatacgg aaaagatcaa gtaaaaacat ggcgcagagg atatacggaa
     1561 gttccgccgt taaccgcaga aaatagattt gaccgcagat atgatcactt ggatccgcat
     1621 ttgatcccat acggagaaag tctggaaatg acagtgaatc ggatcattcc cttatggcaa
     1681 gatcatctag caccaaaact aaaagatcgg caagatttac tagttgtggg tcatggtaat
     1741 agcatccgag cactgacaaa atatttagaa gatgttcctg aagatcaaat ggatacgatc
     1801 gatatcccaa atgcacaacc aatccagtat acattagcag atgatttgac aattctggac
     1861 aaaaaaatac tttaaagaac acctttatct aaaagtgaga gatagaaaaa agaagcaaag
     1921 gaatggaaca aaaggaacat gaaaaattat atatgggact ttgatggtac attgtttgat
     1981 acgtatcccg caatggtaga tggtgcatgg caagcactaa aagattttgg tatcagtatg
     2041 gacaaaaaag aaatctactt caaaatgaaa aagtattcta ctagttattt gatcaatgaa
     2101 tcaaacttga atgccagaga gtttaatgaa ttatttcacc gatatgaaaa agaaagtacg
     2161 gaagtttccc gtccatttcc agaaacgaaa caagtactgg aaatgctaaa agacaacggc
     2221 ggtcgtcatt tcatcctgac ccaccgtttg acagaatcaa catggggcct gttaaaagaa
     2281 catcgattgg cacatctgat tgaggaagta gtagggatcg atcaggactt tcctcgtaaa
     2341 cctgatccag catctttaaa ttatttgatc gatacttttc atttagaaag aacagacacg
     2401 atgatgatcg gcgatcgtcg tttagatatc gaagcaggga aaaatgcagg agtcgctact
     2461 tgtctttacg acatcgatca ttttctgggt gagatcccgg cagattatgt ggtaggaaat
     2521 ctgaatgaaa tccttacctt gcagagcatc attaaaaagt agtatcccct ttcaaaggag
     2581 atatgttata attttcataa aggagtgata aaattatatg gaaatcagaa gacaaaaaga
     2641 agttgtagaa gcatttcatt atgatatgag attgccgaac caagaagtag aaacagattt
     2701 gaaagtaggc ttctcgcctt taaaagaaac gatcgaaaac tatccgaaag aacatagcat
     2761 cgtaggagca cgcttagagt tccgtttagt gtttgataca tatgttttat ctggaagtgt
     2821 gagtcagatc aatcatatcc tcaatcggaa aattgaaggt caaaatgatg tcacacaaga
     2881 agaagtggac gagctagtag caccgttatt cgatatcgta cgccgaatgt cttatgaggt
     2941 gacagagatc gccttagatc agcctggggt aaaattgaat tttcaatcag aaaaacaaga
     3001 atagacagta aaaacatacc tgcgatagat taaagctatc acaggtatgt ttttttatta
     3061 ctaattgtaa gcaaaaagaa tgtcatttcg ataaaaatcg tctaaaatat aaaagtcact
     3121 gaaaaaaatt ttttcaggag gatggttgaa gaatcattct cgggaacctt tacttccttc
     3181 gatggacttg tcattaataa tatgaggagg agaaaaatga caacactcat cacagtttta
     3241 gtggttctag tttttgcggc attattatat gtgttctatc gtatgcaaaa gcgccataca
     3301 aaattttcaa cacgcgtctt tacagcatta ggagttggta tcgtctttgg cggtctgctt
     3361 caattgatct ttggtgtaga cgacaaagtc gttactcaat caatggaatg gatcgggatt
     3421 gtaggtcaag gatatgtatc attcttgcaa atgctagtta tgcctttagt gtttatttcg
     3481 atcattggtg cattcacaaa aatgaaagtt tctgaaaagc tagggaaaat tagtgcgact
     3541 gtattgactt ctttacttgg aacaacagct attgcagcat tgatcggaat tggttcaaca
     3601 atgctgttcg gactccaagg agctaaattc acacaaggag ctgcagaaac agcacgaatc
     3661 tctgaactgg caacacgtca ggaaacagtt gaaaacttat cgattccaca gcagatttta
     3721 tcctttatcc ctaaaaacgt ttttgctgat ttagcaggta gtcgtgcaac aagtacgatt
     3781 ggagtcgtta ttttcgcggc atttgtcgga atcgcttatc taggcgtgaa aagaaaagcg
     3841 ccaaaagaag cagcattctt ttcagattta gtcgacagtc tgtataaaat cattatgcgg
     3901 atcgtgacgc ttgttttgcg tttgacacct tatggagtat ttgctttgat gacaaacgtt
     3961 ttggcaacaa gtgattttgc agctatcgtc aatttaggta aatttgtcgt tgcttcttac
     4021 gtagcattgc ttgctgtttt gattgtccac tcactgattt tgattggtgc aaaagtcaat
     4081 ccaatcaact atttcaaaaa agcctttccg gtattgagct ttgcgtttac ttcacgttca
     4141 agtgctggag ctttgccatt gaatatcgag actcagacaa aagctttagg agtagatgat
     4201 gcaacagcta atttctcagc aagttttggt ttgtctattg gacaaaacgg ctgtgctggc
     4261 gtttatccag ctatgttggc aacgatcgtc gcaccagcag ctggagtgaa tgtctttagt
     4321 ttggaattta ttttgatgct tgtggcaatt gtaacaatca gttcttttgg tgtagctgga
     4381 gtcggtgggg gcgcaacatt tgcttcactg atcgttttag gggcaatgaa cttgccagta
     4441 gcaatcgttg ggttagttat ctctgttgaa ccattaatcg atatggcacg tacagcagta
     4501 aacgtcagcg gtagcatggt agctggtatc gtgacaagtg cacgcatcaa agatttagat
     4561 cgcgatgtca tcaatgatga ttctaaagtg atcgatgtga atgcatagtc aaaaagaggt
     4621 tgtgatagaa gtggtcagct ttaagaaata agaagaagtt tcctaaaaat agtttctcaa
     4681 atttttgtga aatttcggct tatttccgag aagctacttc tgaaacaccg tgaataagag
     4741 gttgtgaaaa agctgccctg catcaagtaa taagaacagc caaacaaaaa tagttcctca
     4801 tattttacgt ttggttgagc ttattaccgc agatgcaagc ttttgaacac cgtttaagaa
     4861 agaggtcgtg agcctgccgt ttcactctga gtcacaaaga gcaatttcaa aaaatagctt
     4921 ctcatgtttg ttgaatattg tgtcttgtga ccgaggagtt gtcaggagaa caccgtttac
     4981 cagaggttgt gacttgtttt tagtcacgac ctcttttttt atttattcca tataaataca
     5041 cattatttat tccgaaaagt gaaagcgcaa ataacaaaaa caaccaactt atttattatt
     5101 aaagaaaagc gtatttaagt aggacgattc tgttgagagc tttcgtagat tttcccattt
     5161 tcctatggta aactgacaaa gttgagaatg ttagaacaga tcgtttagga ggaaacagat
     5221 gtttacgaat gaaataaaaa tcatgcttta tgtggacgat gtagaaaaaa atgcaacgtt
     5281 ttggagagca gttggctttg cggaaaaaga tcgtcaagaa atggatggga cgcttataat
     5341 tgaagtagga gttgaggaca gtcaaacctc atttctgtta tatgatcgag catttgttga
     5401 gtcccattca cctggcacag ctactagtgc cccatctttg atgttttaca gtaaagatat
     5461 ctttggacta tataaaaaaa tgcagacgca atcagtcaca ttaggtgata tggtacagct
     5521 tggagaagaa tatgtcttta actttgctga tcccgatggc aactactttg cggttacagg
     5581 taaataatag aaataaagac tttgtttttc tgtgcgaaac aggaaagcga agtcttttta
     5641 attcaaataa taatattatg taaacaaaaa actttccatg cgtaattata cacaagcaaa
     5701 taaatcgtca aatgcgaacg ccttctttat actgtttagg aacgaaaaga aggaaggaag
     5761 aaatacatgg attatcaagt actgctttat tacaattata caaaaatcga agaaccagag
     5821 gaatttgcca aaaatcattt agccttttgc aaatctttgg atcttaaagg tcgtattcta
     5881 gtagctgaag aaggaataaa tggtactgtg tctggaaccg ttgaaaacac gactgcctat
     5941 atgaaagcaa tgaaagctga tcctcgattt gctgatacga tgttcaagat cgatccaagc
     6001 gaaggacatg cctttaagaa gatgtttgta agataccgtc cagagcttgt aagtttaaag
     6061 ctagaagagg acattgatcc aaaccaagtg acaggtgcct atctttcacc gcaagaattt
     6121 aaagaagcta ttttagatga acagacagtg gtgattgatg cacggaatga ttatgaatat
     6181 gacttgggac attttcgagg ggctgtacgc ccagatatac gcagttttcg agagcttcca
     6241 gactggatcc gcgagcacaa agaagaattt atggaaaaac gggtagtgac ctactgtact
     6301 ggtggcattc gttgcgagaa gttttctggt tggcttgtcc gtgaaggatt caaagatgtc
     6361 ggacagctgc atggcggtat tgctacttat ggtaaggatc ctgaagtcca aggagaatta
     6421 tgggacggca agatgtatgt gtttgatgaa cggatcgctg tcgatatcaa ccaagtagat
     6481 aaacaaatcg tcggtcgcga ctggtttgac ggaacaccat gtgaacgata tatcaattgt
     6541 agcaatcctg agtgcaatcg tcagattctt gcttccattg aaaatgaaga aaaacattta
     6601 ggagcatgta gcatagagtg tgcgaaacat ccgcgcaatc gctatgttca agaccatgga
     6661 atctctccag aagaagcaga actgcggttt acagctttaa ttaaatagaa aacaatagtt
     6721 ttgattgtcg accatttcca atatgcgcta tactagcgtt gaggatggtg atccacatga
     6781 aatcattgat ttatgctatt ggggatgtcc atggcaaaca tgagcttttt gaaaaactta
     6841 ttcactatta tgatccaaag atccatcagc ttgttttatt aggggatctc aatgatcgag
     6901 gtcctcgtac aaaagaatgt tttttattag gaaagcaatt agtcgaagaa acaggagcca
     6961 tttacctccg gggaaaccat gaagaatatt ttttgcaatt tctgcaatca ccggaggact
     7021 ggtatgcgcc ttatatgaga aatggtggaa aagaaacgtt tgaaagcctg attcacccag
     7081 gggcatcgga ggaatactcc ccaactgaaa tctcgatgat gatccaatcg agatattcag
     7141 aactgattaa atttttagtc cagcgcccct tgtattatga atgggaaaat tatctttttg
     7201 tccatgccgg tgtggatttg acaaagaaag actggcgtaa gacaagtcta agagacttta
     7261 tttggataag ggaaccattt catgaaggga aaaacaatac aggtaagaca attgtatttg
     7321 gacatacgat tacaccaatg ctccatggag atatgcagac aacagacctc tggattcagg
     7381 atcataaaat cggaatggac ggtggggctg tattcggagg gtcattgcat ggggttgttt
     7441 ttgacaagga aggtattctt caagatattg aatatcagaa caacgaagga ccttggcatg
     7501 gaatctgact aatggaaaga atgaaggagc tgtgactttg ttgcggctct ttttattttt
     7561 atagagaata ttgtttcttt cagtagttta acccaggata aaaagtatga tagaataaag
     7621 aagcaatttt tagcagaaaa gaggcatttt aatgacggaa aatttgaacc agacgatcat
     7681 tcagcttgta caaaaagaac tttcagacta tcgtcctaag cagttgacta ctgtacttaa
     7741 tttgttaaat gaaggaaaca ctgttccttt tatcgcgcgt taccgaaaag aaatgactgg
     7801 aagtcttgat gaagtccaga ttcgtgaaat cgaagagcgg tatgcctatc ttgaaaactt
     7861 agaaaaacgt aaaactgaag tgattcggct aatcgatgaa caagggaaac tgactcccga
     7921 gttagaagca gaaatcaccc aagccgtgaa aatgcaacaa gtggaagatt tgtatcgtcc
     7981 atacaaacaa aaacgacgga caaaagcaac gattgctaaa gaaaaaggac ttgaaccact
     8041 cgcgaagtgg ctgatgcagc ttacagatgg agaggtgcaa tctgaagcag aaaaatatat
     8101 tgacaaagaa aaagaagtct cttctgccga agaagcgttg cacggtgctc atgagattat
     8161 tgctgaacaa gtcagcgata atgcaaaatt tcggacttgg attcggtctt atacgtataa
     8221 caaaggtatg tatgtcagca atgtcaagga tgagcaagca gatgaaaaag gcgtatatga
     8281 aatgtattat gactttgcag aacccgtcca taaaatggtt tctcatcgaa tattagctac
     8341 taatcgtgga gaaaaagaag atattctgaa agtattcttt caagtagatg aagcagcaat
     8401 tttagcttac ttggatcgcc aaatagtcaa aaatcctgcc tctccttctt cttcattcgt
     8461 cagagaagcc tatcaggata gttataaacg ctttattcag ccagcaatcg agcgagaact
     8521 gcgcaatgaa ttgactgaaa aggcagatga gcaagcaatc gctattttcg gcgaaaacct
     8581 ccgtaatctt ttgttgcaac cgccactaaa aggtaaagtt gtcctgggat ttgatccggc
     8641 ttatcgtact ggatgtaaac tagcagtcgt agatgcgaca gggaaagttt tagcaatcga
     8701 agttatttat cctcataaac ctgcagcgca agcaaaaaga gaagctgctg gaccagcttt
     8761 tatccaatta attaataaat atcaagtaga tatggtagct atcggaaatg gtacagccag
     8821 tcgggaatct gaactttttg tggctgagca gttgaaatcc gccgaccata aaacctatta
     8881 cgctatcgtc aacgaagcag gcgcttctgt ttactccgct agcgaaattg cacgaaaaga
     8941 atttccgcat ctacaagttg aagaaagaag tgctgtttct attgcccgtc gcctgcaaga
     9001 tcctttagct gaattagtca aaatcgatcc taaagctgtc ggagtaggcc agtaccaaca
     9061 tgacgtttct caaaaacgtt tggctgaaca attggatttt gttgtggaaa cagcggttaa
     9121 ccaagtaggt gtggatgtga atacagcaag cccgcagctc ttgcagcata tatcaggatt
     9181 gaataaaaca actgcccaaa acattgtcat ttatcgtgaa gaaaacggag aattcaccgc
     9241 acgaactcaa ttgaaaaaag tgccacgctt aggaccaaaa gcatatgaac aagcaatcgg
     9301 attcttgcga gtccctggtg ggaaaaacat tttggacaac acaggtatcc atcccgaaag
     9361 ttattctatt gcaaaagaaa tattaacttc agtccaactt tcagaaaaag agcttggtac
     9421 agaagaagca gtagaaaaat tgacacgatt atccgtagag aaactggctg aaagcctatc
     9481 agtcggagaa gaaacgttag ccgatatttt agctgggctg acacaacctg gacgagatat
     9541 gcgtgatgag atgccagcgc ccttattacg tacagatgta ttgagtatgg aagacttgaa
     9601 accagggatg gaattgactg gaacggtccg taatgtcatt gacttcggcg catttgttga
     9661 tatcggtgtg aagcaagacg gacttgtcca tatatcgaaa ctcagcaaaa aattcgtcaa
     9721 gcatcctaca gatgtcgtgt cagtaggaga tatcgtaaca gtttggatag aacaagtcga
     9781 tacgaaaaaa ggcagaatca gtttgacgat gctttcccct tatgaagagt aacaatgagg
     9841 agtaacaaaa attgacacaa gaagaactgc agcagttagt agaagagata tcattaaaaa
     9901 gcttccagct tcctttcaag caccaagcaa tgttcaatcc acgcttacgt acaactggcg
     9961 ggcgctatca tttaaacgat catcatttag attttaatgc gaagctattt gaagagtcag
    10021 acgaagagac gattgcagga atcatcaaac atgaactttg ccattatcat cttcatctag
    10081 ctggaagagg gtatcagcat aaagatatgg atttcaagta tcttttgaaa aaaacaggag
    10141 ggttgcgcta tgcaccagcc ttgacgaaga aacagataaa gatggagtat tatcgatgcc
    10201 aagattgttc tgccacgatc tgccgcaaga gaagaatcga tgtacgcaaa tatcgttgtg
    10261 gaagatgtca tggagaaatc aaatggattg agacaaaaag agaagacttt aatgaagcac
    10321 aaaaaatcag atgaaaggat agaaggcctt tggaaaaaag tgagcagagg aatctaaaag
    10381 actggaatca gctattaaat tttttagccg cacctgaaga gggaaatttt gaggaactga
    10441 cggcacctac acttatttta gctggaaact gtcttcctat cttagctgat aaagcagcac
    10501 aaatgtattt aaatggccaa gtagatcaat tgtttttggt cggaggggtg gggcatgcga
    10561 ctagaatcct ttatgagaat tttgaaaagc aaggatttca ttttgaagat ggcatgagtg
    10621 aaagtgaaat ctgtcgtcag tatctaaaag aagtctatga tttgcccgat aaggcttttc
    10681 tgatagaatc gaagtctaca aattctggag agaacgccac tttttcactg gagattcttc
    10741 attccttagg agctgtacca gaaaaaatct tattgatgaa tgatccgaca ctgcaacgca
    10801 ggactcgagc aacttttgag aaagtatggc aaaatgaaca aactattttc gcgaatgctg
    10861 tgccatttgt gccggaaatc cttcactttt ctgaagagat catctttaca gcaaaagaac
    10921 tgaatcatca atggcctaag gaatatttcc atgcgctagt attaggagaa atggaacgtc
    10981 tccatgacga tgagaacggc tatggtccga aaggaaaaga ttttattcct cacattgata
    11041 tatcagagga agtttggtct tcttacacca gaattaaaga gtcaataaaa acggattttt
    11101 ctcgtacttg accattttag caagcgaatc ctcctttcca aataaatttg gttgaaattt
    11161 tcaatcgttt ataagataat gaggagcgtg ttgaatgtaa tagctaaaag aatggacgct
    11221 agataagaga agaggattca aatggaaaat caaaataaat tgtatcattt tgttggtatc
    11281 aaaggttcag gaatgagctc cttggctctt gttttacatg aacaaggtct aaatgtccaa
    11341 ggatcagaca ttgaaaaata tttctttaca caaagagatt tagaaaaagc aaatatcacg
    11401 attctgccat ttaacgcaga taatgtaaaa ccagggatga cgatcattgc aggaaatgca
    11461 tttcctgatt cacatgaaga aatccagcga gcaaaagaat taggtttgga agtgattcgc
    11521 tatcacgact ttattggtca ttttatccaa aattatacga gtatcgctgt aacaggctct
    11581 cacggaaaaa caagtacgac tggactgctc tctcatgtat tgagtggtgt ccgtccaaca
    11641 agttatctaa ttggagatgg aacaggacat ggtgatccgc aagcggaatt cttttcattt
    11701 gaggcctgtg aatatcgccg tcatttcctt gcctattcac cagactatgc aatcatgacc
    11761 aatatcgatt ttgatcatcc ggattattat acaagtatcg acgatgtatt tacagctttc
    11821 caaacaatgg ctggacaagt gaaaaaagct atttttgcgt atggtgacga tgcttattta
    11881 cgcaaattaa aagcaaatgt gccgatttat tattatggtg tcacagaaaa cgatgatatc
    11941 caagcacgaa acatcgaacg cacaacttct ggttctgctt ttgatgtcta tcatggggat
    12001 gaatttgttg ggcacttcac tgtaccagca ttcggtaaac acaatatctt aaatgcttta
    12061 ggtgttattg cagtagctta tttcgaaaaa ctggatctga aagaagttgc agaagaaatg
    12121 ctgactttcc caggagtaaa acgtcgattc agtgaaaaga tcgtagcaga catgaccgta
    12181 gtcgatgatt atgcgcatca ccctgcagag atcaaagcaa cgattgatgg cgcacgccaa
    12241 aaatatccag ataaagaaat aattgcagtt ttccaacccc atacgtttac gcgtacgatt
    12301 gcattgatgg atgaatttgc agaagcactt gatttagctg ataaagttta cttatgcgat
    12361 atttttggtt cggctcggga agaacaagga aacgttaaga ttgaagacct tggagcgaaa
    12421 atcaaaaaag gtggagaagt catcaaagaa aataatgtat ctccattgtt agattatcat
    12481 gatgcagtag taatcttcat gggtgctgga gatgttcaaa aatttgaaca agcgtatgaa
    12541 aaacttttaa gcagcacgac gaaaaatgta ctgtaataca attactgcag tgtccttata
    12601 aaaatagaaa gagggggagt ggcaaaaatc ttgccaagcc cccttttttg caacttatga
    12661 taaacggtgt tcaaaagctt gcatctgcgg taataagccc aatcaaatca aaaacatgag
    12721 aagctgtttt ttcttggctg ttcttattat ttgatgcagg acagcttttt cacgacctct
    12781 gtaaactata ggaatctgtt aaatcaaggg agcagaactt gccttttacg ctacttttgg
    12841 tacaataatg tatgattaaa aataaactgg agggtttcta tcttgaacat aggtaagccg
    12901 agaaaactag gaaaaacaat aaatgaaatc gaggaaggcg actcgttatc cttaacagaa
    12961 tctattgaag ataaccagct tttgctgtat ttgggattga cgaatgatgc aaatcctttg
    13021 tatatccaac atgactttgc acaaaaaaca gaatatcaac agccaatcgt tccatcagtg
    13081 atgctgatgg ggatcatcac aagtgcaatt tcaaagcatc ttcctggacc aggatcacat
    13141 gttgtcaatt tttctgtcaa ttttattgaa ccggttttcc attatgaaac actgactttt
    13201 cagtttgagg tcataaaagt agataagatg aaggatgtgg tgacgatttc tgtagaagcg
    13261 gagaatacga acgaagatcg tgtgttggat gctgtcgtta tggtccaacc gccacaagtt
    13321 cctgaattgg aaatagcaat cgaaagtgaa ggtgaattga atgaataatc caagtacatc
    13381 aatgtcaggt atcaatcgtt tttatgcaaa agtttatgga tttttaggta tgggacttgc
    13441 ccttagtgca gtcacttctt acttggctct ttgggtattt cctttgcaat tagcaacttt
    13501 tatcaataat tttccactag gctttgtggg tctgtggatc gttgaactga ttttagtaat
    13561 ggttctaggc gtaaaagcac aaaagaatcc gagcttagca atcggtggat ttattgccta
    13621 ctctcttttg aatggcataa tattagcggt tactcttgca tactacgata ttggaacagt
    13681 aacgcaagct ttcttgacag ctactttgat gttcatgggg atgtctgttg tcggagtaac
    13741 aacaaaaaga gatcttagcg gggttggaag agcaggacag gcagctttaa tcggagtgat
    13801 cattgcacta gtcttgaaca tcttcatttt gagaagtagc gtagttgagc tgttcatctc
    13861 cctactgtta gtcgtcatct ttgcagggat tacagcttat gataaccaaa gcatccgtaa
    13921 tatctatgtc cagacaaacg gaacagcaca tagtggaatt gctgtattca tggcattgaa
    13981 gctgtatttg gactttatca acttgttctt ggcgtttctg agaatctttg gacggaacaa
    14041 ctaaaaaaga aaaaaattca tcagttgggg ctataccgaa ttatttggta tggtcccgct
    14101 ttttcttttc gcattccgca ggattctttg ttagaatgaa taagaacttt acagtaagga
    14161 gttaagaaga tgacaaaaaa taaattatta ctcgttgatg ggaacagtgt ggcttttcgc
    14221 gcattctttg cgcttcacaa ttctcttgaa cgtttcaaaa atagaaacgg tcttcataca
    14281 aatgcaatct atgcattcaa tacgatgttt gaaaatgtta tgcaaaaaga gcaaccgact
    14341 catgttctgg ttgcgttcga tgcaggaaaa acgacttttc ggacagaaat gtatgcggag
    14401 tacaaaggtg gaagatccaa aacacctggc gaattcaaag aacaaatgcc atatatacgt
    14461 gatttgttga caggactagg ggtacagtat tacgaattgc ccaattatga agcagatgat
    14521 attatcggta ctttggcaga aaaagtagac aaagatcaat ttgatgtcgt cgtgctttca
    14581 ggtgatcggg atttgactca attagctagt aaagaagtaa aagtggatat cactgtaaaa
    14641 ggtgtcagcg atatcgaaag ctatacacca gaacatgtag cggaaaaata tgatgggttg
    14701 acgccaaaac agattattga catgaaggga ctagccggag atgcctctga caatatcccc
    14761 ggtgtgacta aaatcggtga aaaaacagct atcaagctat tgaaacaata tggctcagtc
    14821 gaaggaattt atgaacatat cgatgaaatg aagcaaagca aaatgaaaga aaatctgata
    14881 aatgacaaag agcaggcttt cttatcgaaa aaattggcga ccatcaatac ttcagcgcct
    14941 gtggatgtct ctatcgactc attgaagtat gaagggaaaa atctcgataa actcgttccg
    15001 ttttataaag aaatggattt caatcagttc ctttctaaat tgaatatcgt agaagaagaa
    15061 gtaaaaatgg atgatatttt gtttgaagtc gttcatgaat tcaaagagga aatgtttact
    15121 acggatatgg cgttgtacgt ggaaatgatg ggcgacaatt atcatacaga ggaaatcgtc
    15181 ggagtagcgt gggggacaga aaagaaaatt tatgtcacga acgatctatc tgtattcgaa
    15241 aaccgagcgt tccattcttg gatcactgat ccgactcggc tgaaaaaagt atatgatgcg
    15301 aaacgaactt atgttgcttt aaaccgctat actggaaaaa cgaaaggaat cgattttgat
    15361 gtcttgctag gtgcatacct tctcgatacg aatgaaaaaa gcacagatat cgaaggaata
    15421 gctgctcatt acggatacaa cgatatccaa tcagatgaag ctgtatacgg caaaggggcg
    15481 aaaaaaggtt taccagaaga agaggaactc ttttttgctc atttagcgcg aaaagtagct
    15541 gcaatcaatg cgttgacacc aaaattgagc caagaactgg cagaaaaaaa ccaagaagat
    15601 cttttccgga aaatggaact gccattgtct atcattttgg cagagatgga aataagcggg
    15661 atcaaagtag atgcgactcg cttacaagaa atgaagggcg agttctctgc tcgcttaaga
    15721 gagatcgaac aaaaaatcta cgaagaagcc ggcgaagaat tcaatttgaa ttcaccaaag
    15781 caattaggag tgatcttatt tgaaaaaatg ggattacccg ttatcaaaaa aacaaaaact
    15841 ggatattcca cagccgtaga tgtactggaa cagcttcgtg aacaagcacc aatcgtagag
    15901 gatatcctca cctatcgtca aattgcaaaa attcaatcta cctatgtcga gggactgctg
    15961 aaagtgatcc aatcagatgg aaaagtgcat acccgttatg tccagacatt gacccaaaca
    16021 ggacgattaa gctctgttga tcctaatttg cagaacatcc cgattcgatt agatgaaggg
    16081 agaaagatac gtcaggcatt tgttcctaga gaaaaagact ggctgattta ttcttctgac
    16141 tattcacaaa tcgagttacg cgtacttgcg catatctcaa atgatgaaca tttgaaagct
    16201 gccttcctag aaggtcaaga tatccatgcc agcacagcga tgcgtgtatt tggaatcgaa
    16261 aaggcagagg atgtcacacc aaatatgcgt aggcaggcaa aagcagtgaa ttttggtatc
    16321 gtgtatggca tctctgatta cggactttca caaaatctag gaatcagccg aaaagcagca
    16381 cagcaataca tcgatacgta ctttgaaaaa tacccaggtg tcaaagaata tatggaaaga
    16441 atcgtacgcg aagcaaaaga ccaaggctac gtcgaaacgc tgtatcaccg ccgtcgatat
    16501 ctgccagaca tcaattcaag aaattacaat atccgttctt ttgcggaacg aacagctatc
    16561 aatacaccaa tccaaggaag tgctgctgat attttgaaaa tcgcgatgat cgaattggat
    16621 aaacgattaa aagaaacagg tcttcaagct acgatgctgt tacaagttca tgatgaactt
    16681 gtcttcgagg taccggaaaa agaacttgaa tcattagata aattggtgaa ggaagttatg
    16741 gaacaagctg tttctcttca tgtaccactg atcactgaca gcagttgggg aaaaacgtgg
    16801 tacgaagcaa aataaacatt gtttaagaca gagcaatata atgaaggtga aaagaaaaaa
    16861 tgccagaatt accagaagta gaaaccgttc gtaaaggatt ggaacggtta gtagtaggaa
    16921 aaacgattca aaaagttcag gtcttgtggc ccaagatcat cgagcaacca gagacaccca
    16981 tctttgaggc ttctcttgtt ggcgaaacca tccaatccat tggacgtaga gggaagtttt
    17041 taatttttca tctcgatcat tgtgaactga tctcacactt gcgaatggaa ggaaaatatc
    17101 aatttacgaa agaaaataca ccaatcgata aacatacgca tgtacttttc ttttttgagg
    17161 atggaagcca acttcgctac aacgatgtac gaaaatttgg tcgtatgaca atcgtcgaaa
    17221 aaggagcaag tgcaacttac cgaggaatca tgaaattggg acctgagcct ttgccagata
    17281 gcttcttatt agcagatttc gcaaatggac tgaaaaagtc ccacaaagca atcaagccat
    17341 tgctgctaga ccaacgtcta gtgactggtc taggtaatat ttatgtagat gaagcattat
    17401 gggaagcgaa gatccatcca gaacaaccgg cgaacacact gcgccccaaa gaggtagaac
    17461 aattacgtct atcgatcatt gatgttttgg atcgtgcaat agaagccgga ggtaccacga
    17521 ttcgcagtta tttgaatgca ttaggagaat caggcggatt tcaagtagca ctgcatgtct
    17581 atcagcaaac tggcaaacca tgtatacgtt gtggaacgcc gatcgtgaaa acaaaagtgg
    17641 cacaaagggg gacgcactat tgtccgaatt gtcaaaggct aaaaatcgca aagtaggatt
    17701 tgttttaggt ttgacgggtg gaatagctac cggtaaaagt acggcagcca aagtctttca
    17761 gtctcatgga tttcctttga tcgatggcga tgtgattgcc agagaaactg ttgagcctgg
    17821 aacgcttgct ctgaggaaaa ttgtatcagt gtttggccaa gaggtattgc agcctgatgg
    17881 gcaactagat cgagggaaac ttgggatgat tgtttttcca tcaaaggaaa aacggcaaaa
    17941 acttgatcag ctattagatc cgtttatccg aaaagcgata aaagatcaaa tcgcctctct
    18001 aagttccaat catcctttag taattgtaga tatcccattg ctctacgaag gtcattatga
    18061 ccactatatg gatgcagtag ctgtcgttta tactacgcca gaaactcagc ttcagcgttt
    18121 gatgaaacgt aatcaactga cgctagaaca agcgcagcag agaattagta gtcaacttcc
    18181 aatcgaagaa aaaaagcagc gtgcggatat tttgttcgac aacaatggaa caaaagaaat
    18241 acttgtggga caaatcgaaa attggctttt tgctaatcgc tttctttgag tatctgtgtc
    18301 aattttgcta tcctgagtat atagaaagtg agggatagcg atgggatcat taaaaaatca
    18361 aaaggataaa gtcgtaggta acgcaaaaga aaaaatcggc gagatgctca ataaagaaaa
    18421 tctaatcgat gaaggtcgta cgcaatcaga aacagcagaa gaaaaagaaa agcagtacca
    18481 agcaagaatc gatgaaatag aagaccagca ggcagaagaa gaagcgaagc ggcaagattt
    18541 gactcaagaa cgaaaaaatc cgacacctga tcgtagtaaa acaccgctcc cagaaagtga
    18601 ccacattccc gatgagcaaa aaatcgagga acagcgaatg aaacactata caggaatcga
    18661 agagaagtta taaaatagta aaaaatcgag atgtgacttg aagcagatga gaaggtgttc
    18721 atctgcttca agttttttgt gctagatgac taaatcagct tttgtgtaag ttatttctca
    18781 gtaatcaagg tgatcagtat tggaaaattg aaatttagta aggacagggg acacaattac
    18841 gcatgaaagt agaaaaaatt gttcttatat ccgtgttttt tgggtaggac agtcgcgttt
    18901 gtgatttgtt tcgtgttata atacaactag ttgtaaagaa agacacatcc tttatataaa
    18961 atgcgatgca agaggtgaga caaaatgaga tgtcccagat gtcaacataa taattcacga
    19021 gtaatcgaca gccgtcaagc agatgatgga cgtgcgatcc gtcgccgtcg cgaatgtgag
    19081 aattgttcgt tccgattcac tacatttgaa cgaattgaag ctgctccgtt attagtaatc
    19141 aagaaaaacg gggaacgcga agagttcaat cgcgataaaa ttttaagagg actcatccgt
    19201 tcagcagaaa aaagacctgt agctatggaa caaatggaac aaatcgtcaa ccatgtcgaa
    19261 aaccgcgtac gcagtctcgg agaaaacgaa gtatcgacga atctaattgg tgaatatgtg
    19321 atggaagatt tagttgattt agacgaaatc gcttatattc gttttgcaag tgtttatcgc
    19381 cagttcaaag atatgtctgt tttcttaaaa gagttgcaag atatcgtgga taaagcaaaa
    19441 gaaaataata aagagaataa taaagaaaac aattaagaaa caaaaaggag gcatttcctt
    19501 ggaaaatgct tggaaagagc ttcaaccaaa aaatatttac caaggaagaa aagcggctcc
    19561 gctgagagaa gacagcaaga acgccttgct gtatctttat cagccactaa tcggcggaga
    19621 agccttgagt atctatttca ccctgttatc agaaatctct caagaatctg gcaaaggtcc
    19681 tgaagggatg catgcagatc tgcttagtag tctaggctgc ggtatcccgc aattttatga
    19741 tgcaagaaaa aagctagaag gaatcggctt actggatgtt tattttaaag aagatagtga
    19801 tctgggacct cgttttattt atgagctgtt agaaccactc attcctaaag catttttcaa
    19861 agactctgtt ctggcttttc ttcttctgga aaaagttggt gaacgacgat tccagaagct
    19921 tacccaattc tttgaaccta aaaggcatac agcagaggga tatcaaaaaa tcacaaaaaa
    19981 atttttagat gtttatcgct tcaatgaagc agtgtacgct gctaatcaag aaaacatcga
    20041 atcgctgaat aaatcttttg aagaatctga atcagtagca ttacttgaag cagattcgac
    20101 attcgattgg cagtttttga atgattggct ggcaaaaaaa catattgcaa gtcttgatga
    20161 tccaatcatc aaacaagtcg acatgtatca tcagctttac ggtttcgatg aattgacact
    20221 tggcgaactg atcagtcaat cttatgactt tagtgaacaa aaagtatctg aaaaagaact
    20281 gcaaaaagcc attttggcaa tgcagagacg tccggtgaag caaacaaaag aaacagttgc
    20341 ggtttctgaa aacagtaatg aaccctcgtc aaacgaacat ttgacaaacg cagcgcttca
    20401 gctgataaaa gaagcacaga gcattccacc gatgaaatat ctggaagcaa tcaagtcaga
    20461 aaaaggcgga tatgtttcta aacaagaaaa ctggttactg caagatcttg tttctcaatc
    20521 aggtctttcc agtagcgtga tcaatgtttt gctgaattat gtactagtga tcaagaataa
    20581 tgctagctta aatgccagtt atgtaaatac agtggcaaat gaatgggcac aaaagaaaat
    20641 cgccacagca gaagaagcga tccagcacat tcggcaaata agtaatcaag caaaacaatc
    20701 aaaacaaaag aagcaaacaa attatcaaac tggcaagcga aatgttcgac gggaaaagct
    20761 tcctgattgg gtcaaccagc caaaagatga aaaacagatc agcagcgaga aaaaagcaga
    20821 gattgaccgc cgttttaaag aatacctggc aaaaaaggag ggtgatatct agtggaagac
    20881 gtaggcaaag aattgaagag gatcatcagc aaacgcaatt atcaagaaaa gtatgctgaa
    20941 atgatcgctg aagtcttaaa tgatgcggat gttcaagctt ttctaagcgc acaccaagaa
    21001 gaattgacac aagcggatat tgaaaaaagt tacgctaaat tgtatgaatt cgtgcaagaa
    21061 aagcgtaaat atcaaaaaaa cgatccaacg atgatcgctc ccggctatga gccgaagctg
    21121 acgttgaatt ttcattatgt ggatgtcact tatgtaccaa cggaagcatt gttagcacgg
    21181 caaagacaag aagaaatcag aagccgagta aaagcaatgg atatgccaaa agatattcaa
    21241 tcggcttctt ttgaaaactt tgaacgtaca gatggacgag gatatgcgag cttagaagcc
    21301 ctagattttg tagagaaata tactgctgat ccaaaagggt atcataaagg actgtatcta
    21361 gtaggaagtt ttggtattgg aaaaacatat ttattaggag caacagcgag agaattagcg
    21421 attgctggat tcaccacgac gctagtccat tttccgacat ttgccgttga gatgaaacag
    21481 gcaatcggaa aagatcaagt ggcagaaaag ttagatgcag tgaaacgttc acctattttg
    21541 atgatcgatg acattggtgc agatgcgatg agtagttgga tacgagacga agtattcggt
    21601 gttatccttc aatatcggat gcaggaacag ttaccaacct tcttctcatc gaattttaca
    21661 atggatgaat tggaacagca tttgtccgtc actcaacgtg gagatgaaga gccgctaaaa
    21721 gcgaaacgga taatggaacg catacgttat ttgacaaaag aaatcgaaat gactggtcgc
    21781 aaccgacgca atggttgaac agttgacaag tccaactgac atttgaccta gtagtaaaag
    21841 caggtcagcg aatcattata tggacagaaa tgaccggaga caatcaccgc aacaagtaat
    21901 gcagaaactt aaacggagga ttttttatga gggctatttt ttctagtata tctgtagttg
    21961 gtctattttt tcttttagca ggctgcggta gcgcagatag caacacaggt tctgttgatt
    22021 cgattgatgc gggtcaaaca gtaaaaacaa gcagtacgaa aacggagaga caaagcatat
    22081 ttgtcggaac gattgaaagt atcactcaag tagaagcaga agaagaaacg cttcagttga
    22141 aactcgtcga tgtcatggcc aaagaagatc cagcgaatat gggaacgtca ttcagcaatg
    22201 acggagtgat cttaaatgct actgctgaaa aaataagcgt ggacataaat gaattgaaaa
    22261 tcggtgacaa agtccaattt acattagttg agatgccgat catgacgatg tctatcccac
    22321 cgcaagttcc tggagattcg attattgatg tttcattgaa caaataacca ataacatttt
    22381 ttcaaaaata agaaaatgtt gttttataga acgaaaaggt atatttttta aggagatatg
    22441 ggaatttttt tattcctagt ctccttattt tatttggaaa atgctataat tatctagaag
    22501 gagtgaagct atgaaccatt tagatttatc tcagcgctta gccgcagtgg gtgactttgt
    22561 ccctgaatcc gctcgtttag cagacattgg atcagatcac gcttacttac ccgttgcatt
    22621 gatattaaga ggaaaaatcg aatatgcagt tgctggtgaa gtcgttcaag gtccttatga
    22681 atcagcacgt aagcaagtca aaaaagatgg attagaagac cgtatcaccg tacgccttgc
    22741 aaatggtcta gatgctatcc agccacaaga tggtattaca gctgtcacga ttgcgggtat
    22801 gggaggttca ctgatccgag atatcctaga agctggcaag ttgaatcaac gcttaagcgg
    22861 acaagaacgt ttgatccttc agccaaacat cggagagcgt acattacgat cttggctgca
    22921 agaaaatcag tataaaatcc aatcagaaaa aatacttgaa gaaaataaaa aaatatatga
    22981 aatcattgta gccgaaaaag aacaaaaacc agttacttac aatgaaatgg agctgatgtt
    23041 cgggccattt ctgcttgaag agaaaagtga gatcttcaaa tcaaaatgga caagagagct
    23101 tcaacaaaga aaagctatcc gtgaacagct caaacaagca gctaatcaag aggcacgtca
    23161 aaaacaaatc gagcaggaaa tccaaatgat tgaggaggtt ttaaagccat gacaatcagc
    23221 ggacgcactt tcatccaaaa gtttgaaagc tattgtcctc agtggctagc tgaagaagga
    23281 gacccagtcg gactgcatat cggaacattg gataagccaa tccaacgagt aatgatgaca
    23341 ttagacgttc gtccagaagt ggtcgaagaa gcaatcaaga aaaaaatcga tttgctgatt
    23401 gctaaacatc ctccaatctt tcgtcctgta aaacggctgg ttactgatca gccacaagaa
    23461 aaaatgtatg cagatttgtt gaaacatgat attgccgtct atgcagcaca cacgaacatg
    23521 gatattattt gggatggact gaatgactgg ttttgtgaac ttctcggtat tgaagtggag
    23581 agttatttag taaagactca tgagattcat tataaaaaac tggccgttta tgtacctgtg
    23641 gatcatgcac agaaaatgcg tgaagtatta gctgcagctg gtgctggtac acaaggtgat
    23701 tataccggta caagttttac ctcgattgga cacggtcgat ttactccgga agctggtgca
    23761 caaccagcga ttgggaaagt agggaagaca gaacaagttc aagaggcaaa agttgaggtt
    23821 attttgccgg aaactatcga aaaacaagtg attcaagcca tgcggtcagc tcatccttat
    23881 gaggaacctg cttatgatct tttcgctata gatgaaccag tcgaaatgtt tgggttagga
    23941 cgagtaggtg aattgccgca agaaatttct atagaggcat ttgtagaaca agtaaaagaa
    24001 gcgttccaac tagatggact gagaatagtc cagccaaaaa atgcaaaatc ctctgtgaag
    24061 cgcattgcga tttgcggtgg aagcggtgaa aaattttatc cgcaagcaat cgcccaaaga
    24121 gcagatgtct atatcacggg agatatctat tatcatacgg ctcatgatat gcaaagcgct
    24181 gggttgattg caattgatcc cggtcattat attgaatcgt tatgcaagca acgatttatc
    24241 gagaaatttg aatcttggaa acaagaagaa aattgggata ttaacttttt cgtttctgaa
    24301 acaaatacaa acccatttca atttaattaa aaggagagaa tactatgtac gaaaatcttt
    24361 tgccacgttt tttacgatat gtcaaaacag aaacacgctc cgatgcaaca agcaaaacga
    24421 ctccatcgac tcagacacaa gttgcttttg cgcaagaatt gaaaaaagaa ttagaagagt
    24481 taggcttagc tgatgttttc tataatgaag ataacggatt cgttatggga acattaccaa
    24541 gcaatgttga tcatgaagtg cgttccattg gatttatttc ccacatggat acagcagatt
    24601 ttaatgcagt aggagtcaat ccacaaatca ttgaaaacta tgatggcgag tctacgatcg
    24661 tactagatgc ggaagaacgc tatacattga atacaaaaga ttttccaaat ttgaaaaatt
    24721 atgaaggcca cacattgatc acaacagatg gcagtacatt actgggagca gatgacaaat
    24781 cagggattgc ggaaatcatg actgcaatgg agatcttgat caataatcct tctatccctc
    24841 acggtaccat caaagtggct tttggtcctg atgaagaaat cggtgtcgga gcggataaat
    24901 tcgatgttga gcaattcgat gtagattttg cttatacagt cgatggtggt cctttaggtg
    24961 agttgcagta tgaaacgttt agtgctgctc aagcaaatat tacgatccaa gggaaaaatg
    25021 tacatccagg gacggcaaaa gatacaatga tcaatgctct acagttagca atcgattttc
    25081 ataatcagct tccagccgat gaagttccag aaaaaacgga aggatacgaa ggtttcttcc
    25141 atttgatggc attggatggg aatcctgaag aagcttctat gagttatatc attcgcgatc
    25201 atgatcgtga aaaattcgaa gcacgcaaag cacaaatcac acatatccaa gaagagttga
    25261 atcagcgatt tgatcaagaa cgaatcaaag tagatatgta tgatcaatat tacaacatga
    25321 aagaaatcat tgaaaaagat atgagcatcg tggaattagc gaaacaagca atgatcgagc
    25381 ttggtatctc tccagtgatc gaaccagttc gtggaggaac agatggttca aaaatctctt
    25441 acatgggtat tccgacgcca aatctatttg ccggaggaga aaatatgcac ggacgattcg
    25501 aatttgtttc tttacaagta atggaaaaag caacagacgt gattgtaaaa attgcagaat
    25561 tgaacacaaa gagttaaaat cgaaaaagaa cagcttatga caaggcgttc gtcccaatga
    25621 tggaatgtca tctgtctaag gctaaagggc aggacaatgg aattggttgt cccgccctct
    25681 tttttgaaga gtaaatagga ggtaaagaat ggaaaagctg ctagtttttt ataacaaaag
    25741 ttcagggaaa gatgagggtg agaaattagc acgctggttt caagattatg taaaagaaaa
    25801 gcagccagaa ttatatgtag aactagctga aactggccca tcgattgatg atgcggaatt
    25861 agtcaagaaa gcagaagcca tagaagctga tactttagta attataggtg gagacggcac
    25921 gattcatcat atcgtccaag cgttccaaaa aacattatct caataccatg tcggattact
    25981 tccaggtgga actgtcaaca accttgcacg tgttcttgag attcccctca aaaaagaaga
    26041 agctgctgac gtgatcctgg aaggcaatgt acggaaaata gactatggtc aagtcaatga
    26101 tgaagtcatt atctctacac tgacaatcgg aatcttagca gatacagcag tttggatcag
    26161 tcaagaagaa aaacagcgtt acggctcgtg gatctttatc aagaagtttt ttaagttatt
    26221 gctgaagaag aaaaaatatc atttggattt agaaacagac gaggagcatt ggaaaggaaa
    26281 atcccaactg ttgacagtca cgatgtctaa ctccgtgggc ggttttacaa attttgacga
    26341 ctcagcgacc ctagatgatg gaaaatttca tgtaacgatc gtaccttcct tagatatttt
    26401 ccgatttatt ttttatttgc ctagaatcat gagaggcaaa ttctatacga tccccggcat
    26461 tacttatttc acagccaaac gcatgaaaat ccaagcgcag gaaaaatctg tgggcactcg
    26521 aacggatgga gacacgacag atgatcttcc agttgaatta tctgttgtat caaaaggatt
    26581 aacagtttat tcaccaaaga aagaagaaaa agcttagaaa tagtagttaa cagaaagttg
    26641 gaagaagagt aatggatgta ttgttacaca atcctttgtg gttttacctt ttcattgtga
    26701 atttttactt attttgtctg atggggtatg ataaacatca ggctagaact agcggctggc
    26761 gtgttcctga gaataatttg atatttgtca gcctgttagg cggtggtttg ggaggattga
    26821 tctctcgaaa agttttccat cataaaactc ggaaaaagaa gtttactata ggattcgctg
    26881 caggtgtact tgttgatttg attctcattt attttttcca ttaaggagca ggagatgtcg
    26941 tctaaaggaa cgaaaactaa aatcattctg aatctgcttt tgctgattgt gatttttgcc
    27001 attatttatt atttaatcaa tcaatcattt gcagatatct ttgccgaatt gctgtctacc
    27061 agtgttgttg ttttggcagc ggctgttata ttagggacag tttaccaaat cgctgaaggg
    27121 cgctcaatca aagaaattgc tgaacctttc gcgccgaatt ttacaacgaa agatgggttc
    27181 ttgacctcta gctatattgc gttttaccga atcgtttcgt ttggtacagg aacgctgatc
    27241 tcggagattt atttttataa caaaaaagga atgaagctat cccagggagc aggggtgaca
    27301 gcactccata tgattatgta caaactggca gtgatcactt atgcattagc tggcttggtc
    27361 atccaattct ctctttttta ttctaatggt ccatcaatga tctggtttat catcgctggt
    27421 atccttttga cgatcgtgat tgttgccttt ttattggcga tgtccgtcag cttgaatgtt
    27481 caaatatttt ttgtcagctt atcgaataag ttatttaaaa gtgagcgttt gcggaaatgg
    27541 gtggatacat gcaatcagca gatctactct ttaagggaaa cggtccaaac cattatccaa
    27601 gacaggactg cgctattgcg gatttatcta tggaatatgt taaaacttgt attttggtat
    27661 gtacttcctt atttgattct gattgaaaac catcctaaaa tagattttct actgaccatt
    27721 tcgtttatca gctttgcagt agtgctttca ggggttattc ctacgcctgc tggtattggt
    27781 tcctttgaat ttgtctattt gttattattc agaccagttg ttggaacagt tgacgcagtt
    27841 tcttcgcttt tactgtatcg tttcagttcc tttatcttgc catttctcta tggatttgtg
    27901 tatgtgattg ctgaacggcg aagagtgatc aaagaagaaa taatagaagt aaaaaaagag
    27961 aataaagaaa atcaagggta ggtcttttat aagatctacc ctttttatca aatcaaagaa
    28021 aaacgttatg gataagataa ttttacgttt gtttggctct ttttttatat acatacaatc
    28081 aattttgttt ttttaagatt tatataagtc gagaaaaaaa gtcaaaaaac tatgtgtata
    28141 ttttgaccaa aattgaccaa agcgatataa tagtttttgt aaagatcaaa gaaataagtg
    28201 atcttacctt taattaggag ggtatacctg tatgaatatt gagaaaatga ctacgacgct
    28261 tcaagaagcg attgctgaag ctcaacagat tgcggtcact cgaaaacatc aagatatcga
    28321 cattgcccat gtatggaaaa tctttttaca atctaatcat tttggtcgaa atttctatac
    28381 ggatgccgga ttggatgtcg aatcttttga acatgaaatt gatcgtctac tggatgagta
    28441 tccagttgtt tctggtggaa acgtccaata tggacaaaac ctcagccaga atttctttcg
    28501 attattgaat gaagcagacc aaatacgtga aagcttcggc gacgagtttc tttcaacgga
    28561 agtcgttatt ttagcgttga tgaaattaaa aaattatccg ttaactgttt atttgaataa
    28621 aaacggatta tctgaaaaag aattgcgtaa aaacatcgaa gagatgagag gaggagaaag
    28681 agtgacctca caaaaccaag aagaacaata caaagcatta gaaaaatacg gcgttgattt
    28741 agtacagcaa gtcaaaagcg gaaaaatgga tccaatcatc ggtcgtgatg aagaaatccg
    28801 tgatgtcatc cgtattcttt cacgaaaaac aaaaaataat cctgttctga taggagaacc
    28861 cggtgtaggg aaaacggcaa tcgttgaagg gcttgctcaa cgtatcgtac gcaaagatgt
    28921 gcctgaaaat ttaaaagata aaacgatttt ttcattagat atgggtgcat tgatcgctgg
    28981 agcaaaattc cgtggtgaat ttgaagaaag actaaaagca gtcttgaaag aagtcaaaaa
    29041 aagtgatgga cgtatcctct tgttcatcga tgaaatccac aatatcgtag gggcaggaaa
    29101 aacagaagga agtatggatg ccggaaatct gttgaaacca atgcttgctc gcggtgaatt
    29161 acatttgatc ggtgccacaa ctttagatga gtaccgtcaa tatatggaaa aagacaaagc
    29221 gttggaacgt cgctttcaaa aggtattagt caaagaacca acagtggaag atacgatcag
    29281 tattctgcgt ggattaaaag aacgttttga gatccaccat ggtgttaaca tccatgacaa
    29341 cgcattagta gcagcagcta ctttatctga ccgttatatt actgatcggt tcttaccgga
    29401 caaagcaatc gatttgatcg atgaagccag tgcaacgatt cgggtagaaa tgaactctat
    29461 gccaacggaa ttagatcaag ttactagacg tttgatgcag ttggaaatcg aagaagctgc
    29521 actgaaaaaa gaatcagatg atgcaagtaa aaaacgcttg aaaaatttgc aagaagaatt
    29581 agctgaactt cgtgaagaag caaatgcgat gaagatgcag tgggaaacag aaaaagaaga
    29641 agtcaattct gtttcagcaa aacgtgctga aatcgataaa gcaaaacacg aattagaaga
    29701 tgcagaaaat aactatgatt tagaacgcgc tgctgtattg cgtcatggta cgatacctca
    29761 attagaaaaa gaattgaagg aattagaagc taaagcaaaa gacagcgaga ttaagatggt
    29821 tcaagagtcc gttaccgaaa atgagattgc tcaagtcgtt ggcagattaa cgggtatccc
    29881 cgtaacgaaa cttgtagaag gtgaacgaga aaaactaatt aaattgaatg aaacacttca
    29941 taaacgagtg attggtcaag atgaagcagt tgatgcggtc agtgacgcgg taattcgttc
    30001 acgggctgga ttgcaagacc caaatcgtcc tctaggttct ttccttttcc taggaccaac
    30061 tggtgtcgga aaaaccgaat tagcgaaagc gttagctgag aacttgtttg actcagaaga
    30121 tcatatggta cggatcgata tgagtgaata tatggaaaaa catgctgtgt ctcgtctagt
    30181 cggagctcct ccaggctatg taggttacga agaaggtggt caattaacgg aagctgtcag
    30241 acgaaatcct tatacaatcg tcttgttgga tgaaatcgaa aaagcgcatc ccgatgtctt
    30301 caatatcttg ttacaagtcc tagatgacgg acgcttgact gattcaaaag ggcgagtagt
    30361 agatttcaaa aatacggttc tgatcatgac cagcaatatc ggttcacagt tactgctgga
    30421 aggcgtgact gctgatggaa cgattccaga agcagtggct gaacaagtca acacgctatt
    30481 acgtggaaac ttcaaaccag aattcttgaa ccgaatcgac gacacgattt tatttacacc
    30541 attgagccta gacaacgtga aaggaatcgt tgacaaaatg gtggcgcaat tggcacaacg
    30601 tctggaacat caagaaatcc tgctgacaat cagtgatgaa gccaaaacgt ggattgctga
    30661 aaatgcttat gaaccagcat atggtgcaag accattgaaa cgatttatca ctaaggaagt
    30721 agaaacacca ctagctaaag aaatcgttgc aggacatgtt atgcctaaat caaaagtaac
    30781 gattacttta cttgatggac aacttcattt caaaacagaa gagctagaag aaatcgtcta
    30841 atcttccatt gagactataa aagaaaaaag gggtctgaca caactagtgt cagacctcct
    30901 tttttcaaat aaacagtgtt ccagaagtag tttcttcgaa aaataagccg aaatttcttg
    30961 aagctgcccg cttctgtcac aacctctttt attaggtatt tttcactttt tctaatttat
    31021 aactttcaaa gtaacgctca tcttttttac tttgagacca tgcaaacaat cccattaagg
    31081 cagcacctat cgtatttgtc agcaagtcgc ccatcgtatc catcaatgct gctcgtccga
    31141 caaacagtgt gccatcagaa gcagcaaaac gttgaagatt catgcctaag aactggtcgc
    31201 ataagaattc ccagaactcc caaaacacgc cgcaaagtcc agcaaacgca aagccgaata
    31261 agaggaacaa ccaaggactg gtttttgata tctcagcatc tttcatcaag taaccaatca
    31321 atccatagcc aagagctgtc aggaccattg gactcaccgc atgtaagatt ttgtcccaaa
    31381 aagagatgat actgatcaaa tgcatccctg tgcctaaaaa gacagagatg aacaagaaaa
    31441 accagtaaaa caaaacgatt gctgctggta ttttaagttt gaaaactttc aaaatgactt
    31501 gtggcatgaa aatcaatgca atccctaata aagattccac gataaatgtg attccttgag
    31561 aagtcgaata tttttgtgtg ataaattcat aaaaattata gcagacaacg aatacaccaa
    31621 aagcaagtaa agctatttgc acctttttga tttctttaat cactgaaagt ccctccatct
    31681 aaaaatcttt ttacttctga aagcaactca atttctgaag aaaccacttt tccgttcaat
    31741 ttgatcaaac ctattgtata taagttcagg tagtgaaatt gattttcagc tgtttcttgt
    31801 agtgcagcga tttttttcgg gtgggttccg ccttgctgtc gagtatcagt atataagccg
    31861 atcactggga tgcctttcgc ataagccaca ccgatttccg atgctacccc ggcatcgatc
    31921 gtcagcccat ctagtaaagc aatcattaaa tcactagcca acactttttc tgtgtcagca
    31981 agagcaatca ttcgactgtc tgcataagca gttttgtcat tgattgcttc attttcttga
    32041 ggaagataga tcgaaagctc agaagagagc tctctgattt ctttaactaa ctgttggtta
    32101 tataacaaat cacttttagc aaacattggt gcggcaaaat aaattttcat ctaaacatca
    32161 tcctttttat caaaaataat cgctaaagta agcttccatg tttggaatga tacgctctag
    32221 tgacttcagt gtttcttcat ctgtttctaa ccgttcgatt cttgccaaat aagaagcacg
    32281 gcgataattc atcatcaagc aagtcaatgt ttggatatcc agtcgaacgg attttcctat
    32341 aggttcattt aagacacgga cttgtccctg ttcatcccat gttaaagcga agacaccatt
    32401 attccaagga gcgacaggat cttcaatgat gaaatgaaaa gcatcagctg ttccaacaaa
    32461 cggaaaccgt tgaaggaatt cttttacatc aacgatccga gccataaaat atggttcgat
    32521 ctgctctttg atctgactat cttcaatcaa aaatgctaaa ggctcatttt tataaatatc
    32581 tccatgtacc cagtagatca tggaaaaatg tgcggaaata aagttccata agccatttcg
    32641 agcttcttga tcaagataga acatttcttt tacgtgaaat atttcttcag ctacccagta
    32701 gaacagaaca cctcttggtt catggttgct atcgtagtag acagcggctg tgcgctcatc
    32761 ttcattttcg aaacgccaat actcttccca atgaaaatca ctgcggaata aagcaccatg
    32821 gttttgttgg gcaaatttgt cataaacgga aaatacgtct ggatgatcaa ctggtaatcg
    32881 ctcaaccata ccacttactg ggatttgttt aggtagctgt gtatctctga ttttaaagga
    32941 aagtttatca gacatgattt cccatccttt acgccgatag taggggatac tgtaaggata
    33001 caaataagag atccattgct tattcttgcg catattatcc aatgcaacga taattagatc
    33061 ttgcatcaat ccatggttag catattctgg ataagttcca actccagtca caccacccat
    33121 tttataacgt gcaccgtgaa tattgacttc acaaggatag atagcgattt gagagatcag
    33181 tttattttcg tggaaccatc cgaacacttt cgatacttcc aaaatcggtt ttttggaacg
    33241 gataaaagct cgtttattct caaacccgct ttcctcgatg tctgcttcag tcacttggaa
    33301 cacataggaa agcaattcat tgaattgatc gatatgttct tgagtgaccg gttttaattc
    33361 aagattttct ctaaaatctt tttgatccat tttttcatct ccatttatta gcttgataac
    33421 agtatagcaa aattctacaa aaaaaacttc tatagctgac taattaaaaa ctctttaaat
    33481 tactgctttt cgttggtata atggaaagtg ctgattatat gaaaagagga gacgctatgg
    33541 atataaagaa aatgaaagaa cgccaagagc agattcgtaa tttttcgatc atcgctcata
    33601 tcgaccatgg gaaatctaca ttggccgatc gtattttaga aatgacgcac actgtgacgt
    33661 ctcgcgaaat gcaagatcag ctgttagact cgatggattt ggaacgtgaa cgtggaatca
    33721 cgattaaatt aaatgctgta gaactcaatt acacagcgaa aaatggagaa acatatatct
    33781 ttcacttgat tgacacccca gggcacgtcg acttcaccta tgaagtctct cgaagccttg
    33841 ctgcctgtga gggtgccgtt ttagtggtcg atgcagcaca aggaatcgaa gcacaaacat
    33901 tggccaatgt ttatttagcg ttagacaatg atttggagat cctgccagtc atcaataaaa
    33961 tcgacctacc cgcagcagat cccgaacgtg tccgtcaaga aatcgaagac gtaatcggaa
    34021 tcgatgctag tgaagctgta ttagccagtg ccaaatcagg gattgggatt gaagatattc
    34081 tcgagcagat cgtggaatat gttcctgcac caagtggaga cttagatgca ccgctaaaag
    34141 ctttgatctt tgactctatt tatgatagtt accgcggtgt tgttctaaat gtccggatca
    34201 cggacggtat ggtcaaaccc ggagacaaaa tcaaactgat gagtaatggc aaaacatttg
    34261 atgttacaga ggtcggggtc ttctcgccaa aagcagttgc tagagacttt ttgatggtcg
    34321 gtgatgtcgg ttatatcaca gcaagtatca aaactgtcca agatacacga gtaggggata
    34381 cagtaacgtt agcagacaat cctgccgctg aagctttacc aggttaccga aaaatgaatc
    34441 cgatggttta ttgtggtctt tatccaattg atacttctcg ttacaacgat ttgcgggaag
    34501 ctttagaaaa actgcaattg aatgatgctg ctttacaatt cgaaccagaa acctctcaag
    34561 cattaggttt tgggttccgc tgtggattcc tcggacttct tcatatggat gtcgtccaag
    34621 aacgcttgga acgggaattc aatctagaat tgatcacgac tgcaccatcc gttatttacc
    34681 atgttaataa aacggatggt acgactgcta cagtagataa cccggcagat tttcctgaac
    34741 ctgtaacgat tcaggatgta gaagaaccat tcgtcaaagc acagatcatg gtcccaaatg
    34801 attttgtcgg tgcagtaatg gaactttctc aacgaaaacg gggagaattc attacgatgg
    34861 attatttaga tgattaccga gtaaatgtcg tctataatat tccgctttct gaaattgtct
    34921 ttgacttttt cgacaaattg aaatcaagca cgaaaggcta tgcctcattg gattatgaaa
    34981 tgtctggtta tcaaaaaagc aagttagtga agatggacat cttgctgaat ggagaaaaag
    35041 tcgatgcatt aagctttatc gttcaccgag actttgccta tgaacgtgga aaagcaatcg
    35101 ttgaaaaact gaaaaaacta atcccacgcc aacaatttga ggtgccaatc caagcagcta
    35161 ttggacaaaa aatcgttgcc cgttcagaca tcaaagcctt gcgtaaaaac gtcttggcta
    35221 aatgttatgg tggagatgtt tctcgtaaac gtaaactctt agagaaacaa aaagaaggga
    35281 agaagcggat gaaacaaatc ggctccgtcg aagttccgca agaagccttc atggccgttc
    35341 tgaaaatgga tgagcaagat agtgtgaaat aacttataat caatcgaaaa acctattaaa
    35401 taaacctttt tgagtagatg caacactgag gattatctgt ataaaagatt ttaaactgtc
    35461 atttggttat cacggcgata ctaaaattaa caaaattgga atatttttct tgaagatttt
    35521 tagctgtcag tatatgatga aagcatctca taggaggtgc ttttttcatg gttgataatt
    35581 caagtggaag ggttcttaaa tctctaagaa aagagaaaaa actatctcaa aaaaagttag
    35641 ctgatttagc aggtatttca caaagtactt tagttaaata tgaaaaaggg tcaagaaaaa
    35701 tccctaaaga cgtagataat actctaagca agattctgaa tatagaaact ctaataaaag
    35761 atgaggaaga taagattgag attctcatcg gtaaactaat tgcatacaga gatatgaata
    35821 agttacttaa caaagagtta gctgataata taggaattag tgaagtatta ctcagttatg
    35881 tgttaaatag aaagagaaat ccgtcaaaag aaatgcaaaa aaaaatcgat atttttctat
    35941 taagtaatga aaaagaaatt ttgaaggaga ttaatcgtga tagtgagata tttagtttat
    36001 caaaagacga taaaattgtt atgggaaaaa gaatacgaga agtccgaaag aaccgggaag
    36061 agacgcttga aaaatttggt aaaaacttta ccatctatac aggcaaaaat gttataagta
    36121 gatgggaaaa aggtattaat attccagata ttgaaaaact aatgaatatt gcctatcttg
    36181 gtaaggtcac tgttccttac cttatgtacg gagaagatta taagaatata cttccaaaag
    36241 atgaaagagt tagcgatttt aaaaagataa attcttttag tatgggatta aggatgagga
    36301 aaattaggaa agattattat ctagaaaggg aggagtttgg aaagcttttt tctccttcaa
    36361 tttcaaaatg gtccatagat aggtatgaga atggtagaga tatacccaat actaatcgaa
    36421 ttatccaata tgcttatata ggaaatcttt ctttagaatt tttgatttac gggatataaa
    36481 aatagtttac gtcgatactt attaagttat cgacgttttt tattatagaa aaaatttata
    36541 aaaggaggtt tcttgatatg ataagaaaca aaaagggttt gttgaaagtt gctttactgg
    36601 cagctttttt ctaagtaact ttttgacaag ctcaatggca acacaagcgg aagaagtaat
    36661 acaagaacta actgttatga ataacagcta gataaaatgg gctatgtatg ttatccaaca
    36721 atttagtaat cactagaagc ctagcgaaag ttcgcttgat aagttataga tgagtattga
    36781 tttgtagtgt ttccaaatca aaagggtaca gagccacatg aaatatgttg tcctctgcag
    36841 cgtcaggatg ggaatccata ccatggagat tcggagatct gtgagggaat acttacgtgg
    36901 ttaatatgtc agttgtgttg gacgtagtaa tggtcatagt gggtagattg actgaattct
    36961 tatatgagaa aatgaaacca acaagaagat agggttattt atacagaatt ggggatcttt
    37021 tctggaaaag taatcggata atgcgagatt cgtacggtct tttttaaatt tctctaaaaa
    37081 aaacggcatc gaatgggttg ggtgattgat aagcaatgaa tcatagactg atatagaata
    37141 aaaaatgatt ctatttatct ttttacatct atcgtttttt caagtagccg caaattatat
    37201 cagcattcaa caatttttgt atacaagttc tagtaaaagg atctgaagaa aaagttggtt
    37261 gttgtgaaga taaaaaaaga atcaggtttt actgagtttt tcttcaaaat ttgtgttatt
    37321 aggttaggac aaagataaga agaagtatga agatttaaaa aaggaatgag gaaaagatag
    37381 taatttccga ttattggagt ttttttattt ataaagaaga agcgaataag ttgtgattcc
    37441 tagatttcgc gcgtgattaa ttaatgagca aaaaatgcgg aaagttttag tgtttaatac
    37501 acgaggacaa agtttcttag gtattgaagg cacacgtgta acggttgatg ggtggtgtga
    37561 ttgtttcgag gttggaaaac atgttgaact tatggcattt actgagctaa aagataagaa
    37621 caacgtggaa tttttcgaga gtgatattgg ttgggacgat catgaagaag tttatggaaa
    37681 atttattttg cggaagggaa attcttatac gaatggggaa gcataagtag cgatttgtta
    37741 gagatcattg ataggattga aattgtcggg aatatttatg agaatctaga gttatttgag
    37801 gtgatagaat gagtgatggt tttgaacaag tatcaataat taaaaatcaa gttcgggaga
    37861 ttcttagaaa aaaaggctat ttggtagata gttattttga aggagattac gaaacatggg
    37921 taggtgtcta tgctcgtcca gagaataaac ctacctattt agatcctacg acgtcagaag
    37981 atgcctattt acaaaatagg tatcgagtag atggttttaa gcaagacttt gcggagtggt
    38041 ttgaatggga aattgaaaac ggagaagtaa aagaagaata agagtacttg ttgtatcaaa
    38101 ataagccagt agaacaacca aaccagtagc tagtaatgac aataatactg aggaatcgga
    38161 tcattatggt atgattgata tttctcttcc agaagatctt aagccagatc ctgtaacaat
    38221 tggcaatagt gtcatgattt ttgattcatt agatgaagct atgtcatatg gttggaaaga
    38281 aattaaggat gaaggtagta attggtatgg catgagattt ggtgatggtg aagttgccaa
    38341 aaaagctggt attccaattg ggaaatggac agttgatttc cacgaagcag gttctttttt
    38401 tgttctgtaa ttatagtggg agggtaaaat cattgatgaa atgtgttcag ataagagcgc
    38461 cagataaaaa tagaagagac agttcacgtc gttatcactt ttggtaacgg cgttttgttt
    38521 tattatataa aattctcagg aaaaggagga attcttgtgt atgcaaaaac gaaaatgaat
    38581 tggttgaaag cactcgcatt ggtggctttt tctcaattct gtttcttggt gggaactgct
    38641 caagcacatg cagaagaaac gacggctata caacctacga tggaagccat tgcccaagtc
    38701 gcttctgaag tgacagaagt ccaaccagca gaagccgggg tcccagctgg tgaagccact
    38761 gttgaacagg cccctgtgac agaagcgcca acggtcaatt ccaaaacgac tctcgatcag
    38821 acgattgggg aaacacaaca cccagggaat agtcctggta cttcacaacc agttgaagaa
    38881 actgcctcaa ttacaacccc tgcttcagaa acgtccactc tagaaggaga aaaagctgcc
    38941 gaagcaacgc cttctgtgca gccagagtct tctgagaaac aagcggaaga aaagaaacga
    39001 atagaagaaa cagtggaaca accagcggct actgctgaca aagaaggaaa aaatgaggaa
    39061 aacgttgaaa aaacaatctc ttcaaccgca gctagtcaaa atcaaccaac gaaaccaaac
    39121 aaagaatcta cggctagtat tgaaaatcaa aagaaaaaag agcagaacat tccaaaaaca
    39181 ggtacaccta cactgttagt aacagtacca accaatcgtt cggttcgtgt tcgccgtgca
    39241 accaatgcag ctgttttagg tggtcggaaa attgattggg gcgaaaatat tggtgttact
    39301 tctagtccga acaatctaaa cttcacttta aattatatgg ttcgttttga gattaatgga
    39361 caagtggcgt tttgtattga gcctggtgtc tcagccgcag aaggtcaagt ttatacagct
    39421 actgctttga aaaactattt gaaaaattca aatgtacgga aaaaaacaag cttgatctct
    39481 tatttaggat atgtcacaaa taaagacaaa tccgatgaac aatacattgc ggcacaattt
    39541 atgatttggg aagctttggg cacaaaaatc ccaatcaaaa atatccgtgt tgattatgat
    39601 cgtcgaaaag cagaaattca acgtttgatt aataactttg gtgaaaaagc aacttttaat
    39661 aatcaaacac atacggtaaa aattggcgaa acgttgaaag taaagaataa aaatgatttt
    39721 ttgaaatatg tgaaagacat tcaaaaacca aaaggtgtca atgtatctat tcacggcaat
    39781 gaagtatgga ttacagtcac aaaagaggca ccggataaag caaaaattca attgaataaa
    39841 attaaagttc aaggtgcgcc attagcctat cgtcgtccag gagctcaaac aattggtgtg
    39901 ttacatccaa cagaacctaa tgcgtctgtt attaatttac aaattctaaa acaaggaaac
    39961 attcgtgtgt ttaaagaaga tgcggaaact ggtgtgaaag cacaaggtgc agcttcttta
    40021 gaaaatgcgg tctatggttt gtatcaagca gatgggaaaa agattaaaga aattaccttg
    40081 aaaaaaatta acggcaaagt acaggcagaa attaaagatc ttgatcctgg caaatatgtt
    40141 ttaaaagaaa tcaaagcgcc aaaaggttat gtgctttctg atgaagcaat tgaaattgtt
    40201 gttgaacctg gaaaaactgt caatgcgacc gcaaaagatc aagtgatcaa aggaaccatt
    40261 gatttagtga aagttgctaa taaagattta gtcgattcaa cgaatccaga taacaaacca
    40321 aaattagctg gcattgaaat cactttgacg tcaaaaacaa ctggcaaagt ggtgaaaacc
    40381 gttgtgacag acaatgatgg ttatgctact tttggtaaaa ataccgttgt ctttgatacg
    40441 tacattcttt ctgaaaccaa aggaaaagaa gggtataaac tatttgaacc acttgaagtc
    40501 acaatttctg aaaatgggca aactttccat tatgttttag aagataaagt aattgaacaa
    40561 cgtcttaaag tggtgaaagt ggatcaagaa acaggaaaag tgattccact tgctaataca
    40621 gaattcaaga tttttgatac tttagccaat cgttatgtca caatggagat tccaaatgat
    40681 acagaaacaa cggatatctt taaaaccaat gaaaaaggct ttttcctaac taacggtaca
    40741 cttacttatg gaaaagatcg ctatcgtttg gaagaaatca aagcccccgt aaattacgtt
    40801 ttgaatcaaa acccattagt gttctcgatt accaatgata cagaaccgat caaagtgatc
    40861 cattttgcga accgtcaagc acggaaaagt gtaaaattat tcaagtatga agaatggaac
    40921 aagaagaaaa cgccgctcgc aggtgtgaac tttaccttgt ataacggtaa aaatcaagca
    40981 attggtgaat ataccactga tcaaaacggg gaaattttag tgaaaggtct agttgccgat
    41041 gactattact tcttggaaaa tgccccatta gaaagtttcc aaccaaatac agataaacaa
    41101 gcattcacgg ttgcattcaa acaaaatgcg ccagatgatg gggaaacgtt agtggtttct
    41161 gtacgtaatt acttgattcc accaaaacta gaaacacaag cgtcaaataa agccgatggt
    41221 gaaaaagtgg ttgatccatt agaaacgatc gtcattaaag acagtgtttc ttataccaac
    41281 ttgtttgtcg gaaaagaata caccatttca ggagtattga tgaacaaggc aacgaatgcg
    41341 ccaattttac aagatggcaa agaaatcaca agtaccttgg cctttattgc agacaaagtc
    41401 aatggcacaa aagaccttga atttgtggtt aatgctagtg ttctgaaagg tcaaacgatc
    41461 gttgtttttg aaaaactttt ccgtgatggc attgaagttg cagcacatgc ggatatcaac
    41521 gatgaagccc aaagtgtgaa agtgaataat ccaaccgttc ataccacggc tgtctttgaa
    41581 gacggattga cagtcgcaga cccaacagga ttgtttacct taaacgatac cgttgaaatt
    41641 accgagattc ttccaggaaa agcatacttg gtcaaaggga tcttaatgga taaagcaacc
    41701 ggtgaaccct tgcttgtgca tggaaatacg gtagaaacga gtgttggctt tattgccaaa
    41761 gcagaaaatg aaacggtgat cgtaccattt acctttgatt tgacaggtat aaatggtcgt
    41821 gaaatcgtcg tgtttgaaag tctttttaga aatgatgaag aactagcaaa ccataaagac
    41881 atcaacgaca aagggcaaac ggtacgagta actaacccaa gtgtacgtac aacggctaca
    41941 cataaaccca ctggcttgaa agaggttaat ccattaacga aagtcaccat tacagacgct
    42001 gtgaaatacc acgatttggt cgttggaaaa acatacacag tcaacggtgt tctaatggac
    42061 aaagtaacgg aaaaaccagt gctagtagat ggaaaagaag tcacaagtac cttaacgttt
    42121 gtggcagaaa caacggatgg tacagtcaat ctagacttta ttctagacgc acgtgcgttg
    42181 cgaggcaaag aagtcgtggt ctttgaagat ctgtttagag aaggcgtatt attggcttct
    42241 cacgcagata ttaccgacaa tgaccaaacc atcaaaatca gtaatccaac cattacgacg
    42301 aaagcgacga ataaaaatgg cggaaaagag atcttggcct tgccaaatca aactgtgctt
    42361 gaatgggtca aagtagacgg tcttgcgatt ggtcaaatct atcgcttaat tgttcaaggc
    42421 tacttaacac cagacggcac accatttgaa ggcactcatg cggaaaaagt ctttgcggcc
    42481 gataaagaaa tgatggaatt cttatttgaa ttcttagtgg acggtcgcaa tcttgcagga
    42541 aaaggcttga gttttgcgga atggctccaa gcgaaaacgg aagatgagaa agaaacgttt
    42601 gaagaagtgg cgaaacacaa tgtagatcta acaaacaaag atcaaacggt tcaaattgtg
    42661 gaagcgccaa aaccaccgca accagtgaaa ccagaacaac gggttaaacc agctactgtt
    42721 gtaccaatgt tgccaaaaac aggtgaacaa acaagtagta tacttatggt tcttggatta
    42781 gtagtattag tcattgcttt aggtataaca ctttataaag tacgtaaagc caaagattag
    42841 tcatgaggaa caagcggtta ggatttttaa ccgcttgttt gattgtaatg tagaaatatt
    42901 tagaatttat tttggttttt aagaggagga aaaactttat ggcagaaaaa gcattgcgta
    42961 tgaagaaaga gtttttaggt caagtatttt tattgggttc acgggaacct aatccaccaa
    43021 aggaaattaa tggtgtgtct gggcgatatg ttcaattaca agcagagtgt tcgcgagaag
    43081 aacagcctgc tttttttgtt tatctcacag ctgaagagga taaaagatta cgattaccag
    43141 aaaaagaggt gcgtatttca tttgaagaag cttattttgt ttttcgtaaa gaacgagtga
    43201 atagtcgtga aacaaatgat atgggacaaa cagagcgtcg aacaactggc tatcaagatg
    43261 ttggtgtctt tttaactggt gtaaaaattg gggaggtttt gtaagatggg attaaaattt
    43321 ccaaataatt atgacattac agaagcatta gatgaaactt gtttaggagc cgtacgcttt
    43381 ggcgcattag aagagtctga tcgtgtattt gataatgaaa caggcgatta tacgggagaa
    43441 attcgatcac agcgagcaca attagttttt ggaaatccag atgaaccaaa gattgcacga
    43501 cgagttaaat ttccagcaga tgtagatttg actggtttta aacgacgtga tcctgtgaaa
    43561 ttaattgatc cagaatatca tgtggtatat attccagcac aagatggcaa tcgtgaatat
    43621 tcagatttag tgatttatgc gaaaggatta gagaaagtag aagctccaac aaataatcct
    43681 aatatgaaac aatcacaaga aaaaggttta gatcaaaaac aaccaagtgt tgattctaag
    43741 gaaaaagaga aaaaataagg tttttttgaa agaataggaa ggagtcttcc tattcttttt
    43801 atctaagata gaaggaaggg gagattttga attcagataa aaccaatcaa atactttgag
    43861 agattgtgct tgttatcaaa atatccaaca attgattgag tattttggag acaatccaac
    43921 gatttttgta caaacaaatg catatatttg tgcggttatt gggcagtgta tgtttttacg
    43981 tgatcttgtt cgtttttcat taccgtacca gtggaaacaa gatcatcagg aagtgatttg
    44041 gattcgtata gtacgaatat gtaatatgtg tgcacaccct tataaaaatc gattaaatct
    44101 ttttcgatta tgttttttta ctaaatgtga tattcctgta ttagttgctt tttgtcaaaa
    44161 gtttttagca caggaaaagt aaaaacagaa aggaggaatg tgacaattga aagctcattt
    44221 tttcaagtat cgtggtcggc gaattcgcta tttcaatcgt tatttatggt tttgctatta
    44281 tggtttcttt ttgtttccat ttttgattct gttaggttgg tttagttgga aagtatttta
    44341 tccacgttta agtacgtttt cgaattggca aatgtatctt attcctggaa taagtattgt
    44401 gttgtatttg ttgctggtta gtgggttaat tttagggttg atgcattggt cgcgactaaa
    44461 agaaggatat tttgcctctg tttattggcg tcagttactt gttcgaatgt taattgacaa
    44521 tcggtttgtt tatacaaaga aacaagttag tgagaaacaa acaagggaaa aaatgagatt
    44581 accaaaagtt tatttttatc aaaagaaaca agaattagtg gtttcttttc ctttagatgg
    44641 tgggcgtttt cacgaacgat ttttaaaaat gggtcatttg ttatctgaag tatttttgcg
    44701 tgatttaatt cgtgaagaac gagaaaaagc ccgaatcaat tatgtattcc tttcagattc
    44761 tggtcggatt cctattgatc aatgtatagc agaaaatgga cgtattcatt taatgaaaac
    44821 tttggattgg gtatatgatc aatcaccaaa tatgttgatt gctggtgcaa tcggtggtgg
    44881 gaaaacctat ttattgtatt ctttaattca agcttgttta agtgttggga cagtagatat
    44941 ttgcgatgga aaagcggcag atttagcagc attaggtgac gtcgatgtat tcaaaggaca
    45001 tgtgttttac aaaataaatg aagaaatgat tatttgttta cgaaatgcat taaaagaaat
    45061 gaatcaacgg tatgcctata tgaaaaccat gaaagatcct aaatatgaac cagggaaaaa
    45121 ttatgcttat tatgggttac caccgcattt tatctttttt gatgaatggg cagcttttta
    45181 tggttcgttg gatatggaag cgagaaatag agtcgataaa ttgattcagc cattagtatt
    45241 aaagggtcgt caagcaggga tgtacattat tttagcaatg caacgaccag atgcagaata
    45301 ttttccaagt ggtgttcggg ataatttaac attccgtatt tctgttggtc gattgtctcc
    45361 cattggttat ttaatgactt ttggagaaga ttttaaaaat aagccatttt acaacaaaga
    45421 tcaacctggt cgtggatatg cttttccagg atttgatgta cctgtagagt tttttgcgcc
    45481 atttgtttac aaagattatc actttatcaa agaatttgag aaatttactg aaatgattgt
    45541 ctatgatttt acagtaaaag aggatagtca agatcaaacg atgggagatg ataatcagtt
    45601 gttacaagaa caactagagc gccaaatgta tttagcaaaa gatccaaaag gaacaagttt
    45661 ttctgatgcg catattttgt aatcaactaa ggaggtgaag ttaaatggca gagagttgtt
    45721 attatagagt agctacagca atacgaatga ttaatccttc tctttcttcc agaacgtttt
    45781 atgattggtt gaatcgtatt gaacaagtaa ctgattaccg ctttttgcgc aaagaacgtg
    45841 tttttacagg aaaagttatt aatcaagtat tgctaacgaa aaaagatata gaacgattga
    45901 ctcgattgta tcattatcga gtagatttag aagaggattt aactttgtca atttatcgcg
    45961 ttttttctcc tgaaaaatat agtgaaataa caaaattaga tcatttaatt ttgtagttat
    46021 tatctatcgg gagggctcta gacgtagtct ggtagccgca ctctgcctgg cggtgcgcat
    46081 taaggctgcg aagcatgggc ctataatgcg cactcgctag cagcgtgtgc agctcacaaa
    46141 gaggtcgtgc gcttgcgcac ggcctctttg tgtaaagccc cccgatatat aatatggggg
    46201 gcagaaataa cataacacat agaaaaaagt tttataaacc cttttgtatc aagtgattat
    46261 ctaaggtcag cagttgtact acttttccca aaaaacgagg gggactagtt gatatatcgg
    46321 tgtttctaaa gggttaaaaa aaatcgattt tgttatttta taaaaggagc gagaaaatga
    46381 caccgattga gctaaaaagc tacagaaaga agttaagtgc aattcataat ataagtggag
    46441 ataaaaagcc gctatcacaa gcaagatttg cgcaattgat gggctgctca aaagattaca
    46501 ttagaaagat ggaacaaggg aaaagaaaaa tcccagagga ttttgaacaa cgaatcaagg
    46561 aacgctttcg attgtatatg aaaagcggaa tagatcttcg agcaatgatt gattatttgc
    46621 gtctttcctt ttttgggaca gactacaaaa cagtgattca acgtgtatta cgaatggatc
    46681 tgacagaatt tgaaacacgt ccaacgggct tgtatctttt tgactgtctt tctgttcgtg
    46741 ggaatatctg ggtgttctgg cattcaaaac gaactgtaac agaaaatgta cttgtgcaat
    46801 tttcaggaca aggttgccgg gaatatgagg aagtcatgcg tgaacaacaa acagattggc
    46861 gaacatggct atattccatt tggaaaaatc aaggaaagtt ggaagctggt tatacacgtg
    46921 tgcaatgtag ccgattcgat attgcgttag atgaactttg gggattggaa acggaagaac
    46981 atttcgatct ctttgaatta ctagaaaaac aaaaagcagg tttattagaa atggacttta
    47041 agagattcca gaatattggc ggttgttttt tagatgatgg ctattttcga agtgaaggat
    47101 tatctttgta ttttggatcg cgaaagagtc ctctcttttt taatttttat gagaaacgtt
    47161 ttgaaattgc gaaccgagaa aaaatttcag aattagaagc attaacgaaa tatggtattt
    47221 ataatcgata tgagttacgg ttagccaatg agaaagcaac acaagcagta gaagcattta
    47281 ttttaggtga ttcaccgaaa cgtttaggag agattggcgt tggtttaatt aatgcaaaac
    47341 ttattgtttg ggatagactg gaaagtgatg cacggattgt tgataaacga tgggcaaaat
    47401 tatttcgttc gatggaagaa ttggatttta cagtaaagcc agaaaaattc tcattagatc
    47461 gttcagaacg ctggtttttg aaacaagtag ctccgacatt aaagttgtta caagaagcag
    47521 atcgtatttt aggaagagac tttgtacaag aagggattga taatgccgaa ctaaatgacg
    47581 agcaacaaaa ctatctagaa tggatgggaa cgtcaggagg gaaaattgca tgaatgcata
    47641 tacgacaaca gaatggctgc gcctgttgga tttaaaggct gcaatcgaag cattaaatga
    47701 aaagatggtt gatttgtctt attttcgttt tcgagttcct tatattgaac aagcggtaaa
    47761 agctggacgt tatcaggaaa aagagaactg gcaagaaatt gcacgcttat tagaagttcg
    47821 taagggatac gaacaagaac tcgaagagtt ggaatttagc cgaaggaaag gaaggctaga
    47881 attcattcgc ttttatcgat tttcattgcc aatacctgcg attttagcgg ttaaaaaagg
    47941 ctgcgataaa atgaagatat atgaaaactg tgtggcagca cttagcagcg aaaaacctct
    48001 tatggaagaa atttcattgg tgactgtcac ttgggaaatg agtcgccagc caacagaaga
    48061 acagacatat ctttctttag aagagattga gatagaatta gaggaaattg gtcgctatgc
    48121 cacttgttct acctattgtg gatcggtcat tagtattgct ggtgtgattg tctaaatgaa
    48181 aaaaattatg atttatgttg gtgcgtattg gtcacgtgat ccaacagtat tagaaaatcc
    48241 agaggcggta cactattgct tgcgccaatt attctatctg tataaagaac gattagaatc
    48301 gttgattcgt cagttaccat atactgacag acgtttagat gaacttcttc taaggtatcc
    48361 agcaatgtat aaacgacgaa aaaatagatt gttaccagaa gagtatccca ttgaaaaaca
    48421 tgaacttgaa gggcgatttg tggcttattt ctatgatgat gttcgtatgc gcttagtaga
    48481 acaacgaatg gaaatagaaa atgatcgcta ctattttatc aattattgta agaagcgtaa
    48541 gtatcaagta actgatgatt tttatgattg tattttacaa gatggggaag tgattctatc
    48601 caaaattgct ccaagttttc gtgaacttgt gccgattgat tttttgaaaa aatgtcattt
    48661 gcggattctt ccgtaaaaaa gagctataaa aggaaagaaa agtagaagcc aaatcggttt
    48721 ctgctttttt atttttttta ggaaggagaa gatggtatgt cactggaatt tttaggagag
    48781 ccaattgaaa aggaagagtt cgtttcgcat tatatggatt tgtttattca ggtgataaaa
    48841 aactttgtgc gattgatgaa ttttatccac gcgaacaaga ctatctagcc gctgaacgaa
    48901 taaaaatcag tttattatgg gaaaaattca cagatgaaaa taaccgaccg ccagattatc
    48961 gctatttatc agattgttta acgaataatg tgctttctaa agaataccta tttcacaaac
    49021 gtgagaaaaa tcaaatgtcg gttgaacatt tttgtgattg ttatattgca ttattgcgta
    49081 gtcaacagtt attaacagta gaacgatatg gtgcagagtt tggttatgtc ttgcaagctg
    49141 agcgtcatag agctacaaga tgctatgaaa aagaagatca agtgattgat ggctatgaag
    49201 aattatgtat tcgaaacaat cgctatttgc aacaacgttt atatgaacaa ttgatgatgg
    49261 atttttcaaa tctctataga gggtatgaat gttcgatgat tcaagaaagg tagaagaaaa
    49321 gggggaattt ttatgtggcg attattattt ttggtggtat gtggtatggc attgttctat
    49381 gtgtatcgtg tctatctcta tccacgaatg gaacgatgga caagttggta tagagatcct
    49441 ttaaaacaac gaaaaggatt gaagcggtat cgttatgaat tacttgttga attttcggat
    49501 gggcgacaag cacagtatta tttttttgca aactatccaa aatacaacac cagtgaacta
    49561 ttgattcaat tattcaaaaa taatccatat gttgggttag aagaaaacgg acgggagttc
    49621 ttttatcgtt cagataatat tagtgcggcg tctatgaaca aaacacgaat tgcataaaaa
    49681 attggaggaa taatcatgaa aaaaacaaca ttagcagtcg taacaacact aggaatttca
    49741 ttattttcgt ttcaattagg gagttcattg gtttatgcag atgaaactgt agaaacacct
    49801 aagtcagaaa ttgtagaaac attgccaggg gaaggattac cagatgttga gacagagcta
    49861 aatggaggaa caacggaaaa accagcagaa cctgaacaat tgcagtcaga gaaacctgaa
    49921 aaagagccag tgacaccaga accagagttt cctgaatcaa ctttaccgac tgattcgatc
    49981 gaagaagaag gtgtgcatag ttcaacaaca acggattcaa gtatagtcac aactccggaa
    50041 caatcaggaa caaccagttc ttctgaaaag aatactgatt cgtcaagtac ggaacagcca
    50101 acgatgtcgt ctaccagtga agaacaaaaa gaagaaccga aacaacctgt tgaaaaatca
    50161 gaagcaattc caaaagaaaa taaacctatt gttccagcaa aagaagtcac agtatcggta
    50221 accccaagcg gtgaaattac gacgaatact tctcaaggaa tgagtgtacc gattgtcact
    50281 agtaatgtag aggaattgac ccatattcca acaccaacca ccccattaaa agtagcaggt
    50341 gatcaaacaa ttgttggtgt aaaagatggt attccattaa tccaagatag tgaagggaat
    50401 ttggtaaagg atttgtcgat tcctgtaaag aaacttccaa gtggcaatat tgaaatcaaa
    50461 acagcagatg gaaaaacaaa agtcttacca aagactggtg aagaaataca tgttgcactt
    50521 tctgttctag gaggagtgtt gacaagtatt gctggatttg ttggatataa aagaaagaga
    50581 aaaggaatag aaaatgaggg taattgaatg gactattttt cagaaaaaca agcttatcgt
    50641 tgtcaatcgt acgtactagt aaaaacatac tagaaggagt agcttatgaa aaaacgacaa
    50701 ctacggcgga aagaaaaagt ttatacagag aaagtaccga agcaaaagaa aatccattca
    50761 aaaaaagcag tgaaatggat ttggtgtttg gttttatttc tttgtttttc agggggcttg
    50821 gcattttttc aatccatgaa aacgaaggtt caagtgtcgt ttttgaaaga tgaaatccaa
    50881 caattacaaa agaaagaagt acaaagtcgg tcagaattaa cgtacacacc tgaaattgaa
    50941 tcctttatga atcgttttgt tgctttgtat atgaatacat tcgataatca tgaacaagaa
    51001 caacaacgtc aagaaacatt aaaaaaagag ttttatgcac aaaactttat tcaagaacca
    51061 ggaagtgttt caggtgttcg aaaattaact gctgcttcgt ttattggatt aaaagaaatt
    51121 gaaaccattc caactgctag ttataaagta acttatgata ttcgctcgat gaatccagag
    51181 agtaagaaag aaacaagtgt gacaatcaca caagtactca atcttccctt ttctatttca
    51241 aacaagggct gtcgtattat tgcttatcct tattttacgg cactaccaaa gaatacagaa
    51301 aaacaacgaa tgattactta tgatgacaca ttatacgaaa cggttgatgc gtcggaagcg
    51361 aaagatgttg aaggatttgt ggaagatttc ttagataagt atgcgaaaaa caatgcaaaa
    51421 gatatgtcat acatgatgaa agaacctgaa ggactcaatc aaacagctaa agttgatcaa
    51481 gtagagatga aagtattgcg ttataaagaa acgaaaaaac cttttattgt aaaagcaacg
    51541 gtcgtctttc gagatggtga tacgtcactt ttacaaaaag aacaaatgac gattgtcatt
    51601 acgaaaaaaa caaatcagta ttatgttgaa aaattaacac ataattggtt ggataggaaa
    51661 ggagaagaac ggaaatgaca ctgaagggaa ttgtagattt tatattaacg caaggtggct
    51721 attttttaat aatggtggtt gtttatctgg gattgcgaaa ttttatgaaa tcaaaagtag
    51781 gaaatgcatt aatatctatc gcagcaggtg ccgcagttta tttcttctta aatgatccaa
    51841 cacgtgtatt tgatgcgttt ggtaaaatca ttgaaaaatt atttatggat taggaggata
    51901 gtgaagtgga ttgggaacct tatgattatt cgattgttta tgcggaacct tatcgcgtac
    51961 aacagattac aagcaattgg cgtcttccat ttccagttgc attagtcaat gcagcaactt
    52021 ttttgttggt cgtaatcttt gaatatttat ttttacgttc atttattggt tgggtcattt
    52081 ctttttttcc accagcagga gttgtttttt atataggact cccctattta tgtgtgttag
    52141 cactggcaaa actaaaacct gatggaaaaa aagtgcattt ttatttatgg gattggtttt
    52201 gttatatgat tcgtatgatg aatggtgatt gtgtgtatta taactgggac aaggtatcaa
    52261 acaatgcatt ggaagaatta ctttttgtga ataagtatgt ttatttagag gattagaaaa
    52321 agggacaatc aactggttgt tcctttttta ttgggaggtg aaattcattg gtgcttgtaa
    52381 aagaaccagt aaaagcattc aagaaaaatt gtttgttaaa tggagaggat tgtatctggg
    52441 cctactatca tgtttttcca cgaacaattt caaaaaacac accaaaaaag acacaggaaa
    52501 taaaagaaat gatggctcgt ttactgttgc ttttagcaga ttatgaagat gtggagttgg
    52561 tgatgtatcc acgaacaatg aatttacgga cgaagtttga cacattagga aagggatttt
    52621 ctcccgatag tcaagcaatt ggtgcgtatt atgcaaaaga aacagtgaca ttgttggaac
    52681 gagaaggtca agtctatcgt ccttcattta ttttaggaat caaagtcaaa gaaaaagcaa
    52741 cggtggagag ttttcatgat gtaataaatc taatctggtt agatttagca ggaagtttag
    52801 cacgcttatt tggattagaa gtagatgatt tggaaacttt gttttctgaa agtgatcctt
    52861 atgtaaaaga agtgacacaa ttactttata gcttttctat tcgtccctta gtaaaaaaag
    52921 agctgttgta tctcaatcgt ctgcaatata ttcgaggaat ggctcacaaa gtagaagaac
    52981 aaaataattg ggaagtactg aaagacaatc aaggaacgta tgtacgtata ccgaaggaac
    53041 ataaaggcct tcttcaatta gaagatgagt tagggagtag ttatttagca ttgttgccta
    53101 ttggggaaac acctgaaaat atgagaaatt gtgatctatt tcaatttgct caggatcttt
    53161 ctttcccagc agaattgcga atgaaaattc actatccacg cttgaaagga cagggaggta
    53221 ttggtttaaa actgaattgg ctatcggaac ggttcaaaac agagcataag gaattggttc
    53281 aaaatgatga agaacctagt gaacgcttat taactgttcg aggattagta aaacatttaa
    53341 agcaacgagt agataatggg caacctgtcg tcgattggat cgcatgtttt attgtatacg
    53401 gtcaaacggt tgaagaagtt cgtcaaaata gtgcaacggt tattcaacaa cttcatacga
    53461 ttatccatat ccaccgtgca aaaaatgatc aacgagaatt gttctataaa tgtttattag
    53521 ggcaaccatt gggacggcag ttacattgga agcaccgaac aactgtagaa gcagttggcg
    53581 aatggttgtt ttcagcagta tcagaattag gtatggaatc cggctggtat attggtcggc
    53641 aagatacatt aggggatggt ggttctcgag gagaaaaaac accattagaa gaattaattt
    53701 atgcgtcaaa tcgttttgtc tttttgaatc ttctagccat tgcggaagga atcaaaggtg
    53761 cgttgtttga tgcgcctcat gtagcagtaa ctggaaaaac cggtaaaggg aagacctttt
    53821 tagttggctt gctctttttg tatagttcgt ttatgaatgt acaaagttta tttgtggatc
    53881 ccaaaggaga aaagcgcaaa tggtttacga aactcattca agacccgtat tatcagaaac
    53941 attacccttt gtttgtagaa catttgcaaa aaatgagtta tgtcacgtta gatgctacaa
    54001 atccccgtaa ttatggtgta ttagatccaa ttgtttgttt atcccgagta gatgcgaaac
    54061 aagtagccca ggatatgatt gatgagttaa gtccgttagg taccaatcac cttttaaaag
    54121 gggcggtatt aaagggaatc caagaagttt tagttcaaaa agaagccgga caacaagttg
    54181 gcttgatgca tgtggtcgac tatttagaac aaatggaaca aaaagaggtt cgagaatatg
    54241 gtgagttttt acgcttgacg gtagaagatt cgattttacg tttaggattt tcttatggag
    54301 aaaacccggg attagacttt aatgccaaaa caacgatttt agagatccaa gatttgaaat
    54361 taccaaatga caatgtccga ccagaactat atacagatgc ggatcgaaag tctttgtgtt
    54421 tgatgattag tttaggtcgt ttttgtgaaa tgtttggaaa acgagatagt agtaagaaaa
    54481 cagcgattta ttttacagaa gcatgggtat ttaataattc gaacgcagga cgtagtatta
    54541 ttgcagcaat ggcacgtgtg gggcgttccc agatgaatca attagtgtta gatacacaat
    54601 ttattggtga cttaggttca gataaagaaa aagggaattt tggtgtcgtc tttgcttttg
    54661 atgaagacag tgagcgagaa aagattttga atcatttacg tttggaagta aatgaagcga
    54721 acttagctga aatgagccac atgattaaag gacagtgttg gatgttagat ccctatggac
    54781 gtgtaggaaa actcaatgta cacagtttgt ttgaagaaat gaccgctgca ttacaaacaa
    54841 cggaaaaaac aagtcactct caagtagaag aacaggatac gttaatcatg caatagaaat
    54901 gaggtgaaac aatggcttat ataaagcata aggaaaagaa atggtgcgtt ttgttttttt
    54961 taacgattgg attcggactg ctttttgttg gtggattggt gtatgcggca gaaaagcagg
    55021 tggatcaatc gatctatgag attgggaaat ttcatattga taccttttct tcttatttat
    55081 ctgatagtga attttcatta ggcaaaatgt tatttggggc aaatggcaca gattttctaa
    55141 aaatgatgac gaatatgttc tttagtttaa gtaaattgat ttggcaaggc cttgattttg
    55201 tcattgagaa gctctatgaa ggagctgcaa tgaacgagtt aattcaccag tttttcactt
    55261 tttcggatac tatttattca aaaatatacg atcctattgg tgcggggatt gtcgtcttgt
    55321 atgtgttata tctatttact cttcgtatat ttagagggaa acattacgca aaaatggtgt
    55381 ttattcgatt tctcttcgtt gtcatttttt caatggtttg gtttggctat ggtagtaacg
    55441 tacctagtaa aggagaagct tttaccaaag ggttaaatga tttgtccgtg gaggtagaag
    55501 gctttatttt ttctgctaca aatagtctag atgaattggc gacaaaagat gtcaatggtg
    55561 ttttagtgcc aacgacacaa aaggaagcca ttcaaaaagt gcgccaactt tattataaag
    55621 cggctgttgt tgatccgtat atattgttaa attatgggac aacaaattta gaagaattgt
    55681 atcaagcaga gattgaacca caagaatttc tagccaagga agcgtcaagt gaagaattat
    55741 ctgatattga gacaaaagtg accactgctg caggagaaga tagagggaaa aagaaggctt
    55801 atcgtgtcta tattcaacca actaaagctg tttataaagc agtcgttggt tctatggtgc
    55861 cattgcttaa tctaagtatt ggattaccac ttgtagtgat tggcatgatt cgttttatct
    55921 ttcaaatgtt ggtgttgtgt ttattacttg tgattccttt ttcattactc gcttcttttg
    55981 ttccagtatt tgattatatg ctcatgaata ccttaaagtc ctttttgggc ttgatgtttc
    56041 aaaaatcttt ttacagtgtg attattttgg tggcattttt gatctataac atagtagacg
    56101 atttaattcc aatgaatact gtttttggtt ttttaggaaa tatgtttgtc aaagcactcc
    56161 tatcaatttt actcattgta aaacggaaag atttattaaa gaaactaggg ttaggagctg
    56221 cagatcaaac tataaacaac acgaaaaaca tagcaagtca ttctttgtct caaatgaaac
    56281 aactgcctgg tcaactatca actgctggac aaaatttggc aatcaaaggt gcaggattag
    56341 cagggaatgt gtatcgagca acgaatccac tcgcttctgc agcgatacat ggatttcaaa
    56401 agtttcaaca aaaacgtaca ccacaagaat cggtaaaagg gaggcaagtg gttaatccct
    56461 ttgaactagg tgggcgttca aatcaagcct tgccttatag tggtcgtcat gttcgttatc
    56521 atggggtaga gcctgaaatg tcttctacca aatcgaaaac agagtggaat tctggtcttt
    56581 caaatggttt gattccaaat tcgtccatga attcagtaag accaaaacaa caggtacaat
    56641 cattggcaca attgagtaag caacaaggga ataatcaaag aaaaccattg ttaaataaag
    56701 gtatcgcttt tgttggtcaa tcgattccgt tgccttctgg aaaagtaccc gtgccacaat
    56761 taacagctgc tggttctctt tcacaacaga ttcgccaagt gaaaaatcag gcgaaaaatg
    56821 ggagttatcc agcaatgcag cagttattga accaatactc tgttcctaat tcgtcggtag
    56881 ccactctatc aggaaatcgt tctgtgcaac aaccggggca acgttcgtct gaaagtaaac
    56941 cgtcgatttc cgcaccaaaa tcgttacaac ctgcattttc ttctttagat aagccaacag
    57001 agcaatcgga aaaaatagaa aaggatccta aaacactgcc gattttggac gcaaaaccag
    57061 gaactgattt tactttacca aaaggacgaa cagtccaaaa accattatcg aagaaaggat
    57121 gaggaagaaa tgaagaaagg gtgtctaggt tgtcttcttt tctttattct tccctttttt
    57181 ctattgccat tctttttttc aggagaactt tctgagcatg gaggagaagc tacaggtcta
    57241 gctgtcgctt ttaatgggga atataccgaa ggattaccga ttttttcaga gattaaagga
    57301 cgtggtccaa tcacagatga acatgcgcaa gcagcagttg gtgcagctgt aaagtatcag
    57361 ttattaccga gtgtgattct ttctcaatta ggctatgaat cagcttatgg acagtcacaa
    57421 tctggaagaa acgatacgaa cttttttggg attacctggt ttcctggttg tccctaccca
    57481 caaggttctg cacgtggaat tggtggttct gaaggtggtt tctatatgaa gtttccgaac
    57541 ttaaaagctt gttatgacta ttatggcttt atggtggcga gccaaagcaa ctttaatcaa
    57601 tgtgtgggca ataaagatcc tggaagttgt ttattgattc taggtcgtgg aggctatgcg
    57661 gcagcaggta ttaccgaagg gagtccgtat tatcgaggag caatgagtat cataacgtcc
    57721 tataacttaa cggaatatga tacttttgcg atcaagcatt ggaatagcct accaacaaaa
    57781 aaaacttcgc ttattgcagg aaaaagtaaa ggcaatgcga aggttttgga tcggatcatt
    57841 ggacgatccg taaataatgg ggaatgttat ggtggtacgg catggtatgt atctcaatta
    57901 ggtggcccac agttaatggg ttctggacac atgtttgcga tgttaatagg ggaagattat
    57961 aactggacaa cctatggttg gcaagtaatc atgaacccaa aaccaagtga tttacaagca
    58021 ggagatgtgg tgaattggca agcaggtggt gcattgtctc ctggaatcta tggtcacacc
    58081 ggaattataa cagatgtttc atatggcgga caacatttct ctagtgtgga acagaatgcc
    58141 gagcaaggac ggattatggc tcggtatcaa cgcacgtaca atcaaacaaa aattcgtagt
    58201 ctggttcgta aggtgaaata agaaaggcag tgactagaaa cgtgaaaaaa gggataattt
    58261 tagtatttag ttggttatgt ttgataggtc ttactggttg tcattggttt tcttctgaaa
    58321 aacaaaaaac acaattgaga acgacagaag aaacaatcga agcagtaaaa gaaacaagtg
    58381 gaactcttca aagtactgaa agtaacagtc aaattggttc attagaagac gagacagcgc
    58441 aacaaatgca aatagatgaa atgacaaaaa atttcttaaa agattttgct agaaaatgga
    58501 gtaatttcac agatgtttat aaacgcaatc aagctgtgag ggactatatg acagatcgtt
    58561 gtattaaaga caatagtatt gatgtagacc cgcatgtaca aatgaaaaca actgggaaac
    58621 tttaccaggt gacacaagat atagagaatc cggatcaata tttgttattt ggagaagaaa
    58681 caatgaataa ggttactcaa tttgtattac ttcaattgaa agtagatcaa gaagctcaaa
    58741 agattgatgc gatcaagatt tattatgtac ggagtgcgta ttaaaataaa aaatgaacac
    58801 tcatatttat tatacaccga agaaatagaa aaaaacagac tgttttttta agaaaaacta
    58861 tgtcattctt tacttgaaaa aagttgttat aggacagaaa ggataaaaca aaaacggaaa
    58921 aaatatgtct tatgaataac tataagaact attctatttt ttaggagatg gatacgagat
    58981 gaaaaaacta attggctata gtgtgatgtg tattggattt gttggtgtgg gattgtttgt
    59041 atcgactgaa tctgcttctg cggctgaatg gtataatcct atctggtata atccgaacat
    59101 tgaatgtcaa aaaggctatc cgtatggacc gacaaatctg aaaaatggaa aatgtagagt
    59161 aaattggaat ggcgttgtag atagtgtaat tactggttca atggactctg ctctacatgg
    59221 ctttacgggt cactagaagg aggaagaaaa tgtctgaaga gaaaaaagaa atcgttgaat
    59281 cattagtagc tttaaaagat tctctttcta agattgaata tgttgatagg caagaaattc
    59341 aaaaactaat tgatgatact attattgaaa tccaagatgc gcgttgtgaa ggtataaaaa
    59401 tttctgtagc tttatctaaa gtaatagaaa aaatgaaccg ttcattagcg tttaatggat
    59461 tgaagctaga tagacaaact agtctgatat gggatcattt aaaagacttg tatgacaagt
    59521 ctaaaagaag tgaacggact gctgtatcaa tcttaaaagg cctttgggga atgaattcat
    59581 aaacaagata tttaaaaagt aacttatttt ttatggagga gaaattatga aaagaataat
    59641 taaaatattt ggtgttttag gtgttttctt attaggttta agtacttttg ttagtactgg
    59701 aacaagtgtg tatgccacag aaaaagtgaa tacagttgat ttagaaataa agaataaatt
    59761 agtagatgaa ttaacttttt attttgatac agttggtttt ttagacgaac atggtgtata
    59821 ccatataaag gattttggtg ctattcgtga acgaatcagt caagataacg aacaaggaag
    59881 agcagcaaga gtcttttatg aacatattat tgttcctaga atggagaaag ttgattggaa
    59941 acgatatgct ggatgtgtag ccattaattc tcttcctgga ggaggagtgg cttgggctat
    60001 aggtacgcag ggagatttta ttgaagcatt aaaagctttt aattttgaaa aagctgcgga
    60061 tttattatta aaaattgcag aaaaacaatt aggaaaagct gcagctaaag agttagctaa
    60121 ggtaaatatt gtagcaggaa ttgcagcagc tgctgctagc tgtgcattag agtaaaagtt
    60181 tatgaaaagt ttagaacaag agcatatggc ttttaaacaa gcaatgttta aagaaaatat
    60241 ctatttaaac cataactata ttcgtgtttc taaggcatgt tcaccagtat tgaatatgct
    60301 tggaggtgga aatggattat atcatttact gtttgtcgat gtttgttggt taattttttt
    60361 accagatgaa ctagttatag tcaatgaaaa aataacaagt aaaaatgaag tgtttaatta
    60421 ttctttaaca agaattaatt acaaagagat taccaagttt tcactagaaa aagttccttt
    60481 ttggggagaa ttttgtttaa aaattaaatg taactggaaa agaatgtatt tctatattga
    60541 tggtgatgat gctcttacat tcggtaaaac tactttttct agttttaatt ttcagtttct
    60601 attaaaaaat aatttttatg gtttattgaa ataaggttgc gaaggaagat gtagagttat
    60661 ttgcactgtt gtgttggtat atctcttaat gctgtgtctt tttggggaga ttaattagtg
    60721 gagtgattat atgagtatag atgattgttt agaagaacaa ataagattat ttttaaagtt
    60781 tttaaaagtt aaagttcaaa ataactactt cacatgttat agttatgcac accctgtttt
    60841 aaatagtctt ccttttaatt ctttagtgca aggattgatt acaaatattg ttttattagt
    60901 ctgtacacca aatgaaatat ttgtaaaaaa gataggcagt ggtatttctt cagtaagatt
    60961 aaaagagaaa gaatatactc aaaagattat tcatattcct aagcctgaaa ttaagcgttt
    61021 tgagataaaa gactattctg ctttagggct gttctcaatt ggttactggt gataaaaaat
    61081 aagaatacta aaactatacg tagaatataa gtaatcggca tcaatcctaa ttatgtgatt
    61141 gaatgccgat ttttgttacg cgctattttt aattatctgt aagaagaata attttatttt
    61201 actcatattc gttttcactt tgaagaagta aattgcaatt tcttataagt taagcagcta
    61261 tgcaaaaggc tatttattct attgtgaaat ataagatgta gttgaaacag gatatataga
    61321 atcaaaatac gaatcttatt ttgatttttc tagttttttg aaaaaagcac cctttgatcg
    61381 ttgtattagt ggaaaagaga aaaaggagca tacttatcat gtcacaaaac tacaactaaa
    61441 tatctaaaca acaccaattt gatgcctatt gaaaaaaagt attgcgaaat gaagccaagt
    61501 ctattagaaa atgaaataat agaataaaag aaaatgggaa accgctgaat gatgtaaatg
    61561 aaggtaagta tccacgaact aattttgatg aacaagatat ctatttttta tttgtattgg
    61621 agatactagt ttaatatcaa aagttatcag cagtcataat tagttatcca atgtaaaaag
    61681 tacaaacaat agttgttatg cagaatagtt tatgaaa
//
LOCUS       DAFLWQ010000006        54918 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.006, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000006 DAFLWQ010000000
VERSION     DAFLWQ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54918
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.006"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            176..856
                     /locus_tag="L1V16_000378"
     CDS             176..856
                     /locus_tag="L1V16_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBN1274744.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            946..1980
                     /locus_tag="L1V16_000379"
     CDS             946..1980
                     /locus_tag="L1V16_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBN1274745.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            1994..2329
                     /locus_tag="L1V16_000380"
     CDS             1994..2329
                     /locus_tag="L1V16_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274746.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            2313..4793
                     /locus_tag="L1V16_000381"
     CDS             2313..4793
                     /locus_tag="L1V16_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274747.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWKLTAGPTS"
     gene            4849..6408
                     /locus_tag="L1V16_000382"
     CDS             4849..6408
                     /locus_tag="L1V16_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1274748.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            6405..7769
                     /locus_tag="L1V16_000383"
     CDS             6405..7769
                     /locus_tag="L1V16_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1274749.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            7940..9010
                     /locus_tag="L1V16_000384"
     CDS             7940..9010
                     /locus_tag="L1V16_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1274750.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            9025..9693
                     /locus_tag="L1V16_000385"
     CDS             9025..9693
                     /locus_tag="L1V16_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1274751.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            9713..10291
                     /locus_tag="L1V16_000386"
     CDS             9713..10291
                     /locus_tag="L1V16_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1274752.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            10692..11603
                     /locus_tag="L1V16_000387"
     CDS             10692..11603
                     /locus_tag="L1V16_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1274753.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(11691..12608)
                     /locus_tag="L1V16_000388"
     CDS             complement(11691..12608)
                     /locus_tag="L1V16_000388"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HBN1274754.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            12810..13247
                     /gene="zapA"
                     /locus_tag="L1V16_000389"
     CDS             12810..13247
                     /gene="zapA"
                     /locus_tag="L1V16_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBN1274755.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            13306..13854
                     /locus_tag="L1V16_000390"
     CDS             13306..13854
                     /locus_tag="L1V16_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HBN1274756.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            13969..16329
                     /locus_tag="L1V16_000391"
     CDS             13969..16329
                     /locus_tag="L1V16_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBN1274757.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEEQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLYDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            16416..16730
                     /gene="trxA"
                     /locus_tag="L1V16_000392"
     CDS             16416..16730
                     /gene="trxA"
                     /locus_tag="L1V16_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBN1274758.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            16912..18690
                     /gene="uvrC"
                     /locus_tag="L1V16_000393"
     CDS             16912..18690
                     /gene="uvrC"
                     /locus_tag="L1V16_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBN1274759.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            18835..19734
                     /locus_tag="L1V16_000394"
     CDS             18835..19734
                     /locus_tag="L1V16_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1274760.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            19727..20989
                     /locus_tag="L1V16_000395"
     CDS             19727..20989
                     /locus_tag="L1V16_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1274761.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            21150..23048
                     /locus_tag="L1V16_000396"
     CDS             21150..23048
                     /locus_tag="L1V16_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HBN1274762.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(23378..24097)
                     /locus_tag="L1V16_000397"
     CDS             complement(23378..24097)
                     /locus_tag="L1V16_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBN1274763.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            24434..24766
                     /locus_tag="L1V16_000398"
     CDS             24434..24766
                     /locus_tag="L1V16_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274764.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            24753..26756
                     /locus_tag="L1V16_000399"
     CDS             24753..26756
                     /locus_tag="L1V16_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBN1274765.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            26775..27245
                     /locus_tag="L1V16_000400"
     CDS             26775..27245
                     /locus_tag="L1V16_000400"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBN1274766.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            27266..27850
                     /locus_tag="L1V16_000401"
     CDS             27266..27850
                     /locus_tag="L1V16_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HBN1274767.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            27865..28851
                     /locus_tag="L1V16_000402"
     CDS             27865..28851
                     /locus_tag="L1V16_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HBN1274768.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            28841..29152
                     /locus_tag="L1V16_000403"
     CDS             28841..29152
                     /locus_tag="L1V16_000403"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBN1274769.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            29174..30955
                     /locus_tag="L1V16_000404"
     CDS             29174..30955
                     /locus_tag="L1V16_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBN1274770.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            30948..32324
                     /locus_tag="L1V16_000405"
     CDS             30948..32324
                     /locus_tag="L1V16_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBN1274771.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            32331..32966
                     /locus_tag="L1V16_000406"
     CDS             32331..32966
                     /locus_tag="L1V16_000406"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBN1274772.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            32996..34351
                     /locus_tag="L1V16_000407"
     CDS             32996..34351
                     /locus_tag="L1V16_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBN1274773.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(34543..35937)
                     /locus_tag="L1V16_000408"
     CDS             complement(34543..35937)
                     /locus_tag="L1V16_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBN1274774.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRTQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            36029..37000
                     /locus_tag="L1V16_000409"
     CDS             36029..37000
                     /locus_tag="L1V16_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBN1274775.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            36997..37779
                     /locus_tag="L1V16_000410"
     CDS             36997..37779
                     /locus_tag="L1V16_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBN1274776.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(37948..38319)
                     /locus_tag="L1V16_000411"
     CDS             complement(37948..38319)
                     /locus_tag="L1V16_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1274777.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            38453..38896
                     /locus_tag="L1V16_000412"
     CDS             38453..38896
                     /locus_tag="L1V16_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBN1274778.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(38939..39748)
                     /gene="yidA"
                     /locus_tag="L1V16_000413"
     CDS             complement(38939..39748)
                     /gene="yidA"
                     /locus_tag="L1V16_000413"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBN1274779.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(39767..41134)
                     /locus_tag="L1V16_000414"
     CDS             complement(39767..41134)
                     /locus_tag="L1V16_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBN1274780.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(41118..41948)
                     /locus_tag="L1V16_000415"
     CDS             complement(41118..41948)
                     /locus_tag="L1V16_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBN1274781.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            42111..42548
                     /locus_tag="L1V16_000416"
     CDS             42111..42548
                     /locus_tag="L1V16_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBN1274782.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            42624..43244
                     /locus_tag="L1V16_000417"
     CDS             42624..43244
                     /locus_tag="L1V16_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HBN1274783.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            43433..43939
                     /locus_tag="L1V16_000418"
     CDS             43433..43939
                     /locus_tag="L1V16_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBN1274784.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            43956..44855
                     /locus_tag="L1V16_000419"
     CDS             43956..44855
                     /locus_tag="L1V16_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBN1274785.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            44942..45826
                     /locus_tag="L1V16_000420"
     CDS             44942..45826
                     /locus_tag="L1V16_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBN1274786.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(46018..46089)
                     /locus_tag="L1V16_000421"
     tRNA            complement(46018..46089)
                     /locus_tag="L1V16_000421"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(46054..46056),aa:Arg,seq:ccg)
     gene            46149..47483
                     /gene="rpoN"
                     /locus_tag="L1V16_000422"
     CDS             46149..47483
                     /gene="rpoN"
                     /locus_tag="L1V16_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBN1274787.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            47632..48723
                     /locus_tag="L1V16_000423"
     CDS             47632..48723
                     /locus_tag="L1V16_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HBN1274788.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            48764..49765
                     /gene="gap"
                     /locus_tag="L1V16_000424"
     CDS             48764..49765
                     /gene="gap"
                     /locus_tag="L1V16_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBN1274789.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            49875..51065
                     /locus_tag="L1V16_000425"
     CDS             49875..51065
                     /locus_tag="L1V16_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBN1274790.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            51169..51924
                     /locus_tag="L1V16_000426"
     CDS             51169..51924
                     /locus_tag="L1V16_000426"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBN1274791.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            52040..53338
                     /gene="eno"
                     /locus_tag="L1V16_000427"
     CDS             52040..53338
                     /gene="eno"
                     /locus_tag="L1V16_000427"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBN1274792.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            53737..54876
                     /locus_tag="L1V16_000428"
     CDS             53737..54876
                     /locus_tag="L1V16_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HBN1274793.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        18246 a         9575 c        11605 g        15492 t
ORIGIN      
        1 aaatattttt tcatacttaa taaaaaagga agaatattca tgtaaacgat tttattgttt
       61 ttttctcttt tatacaaaaa gggtcataat ttcaagtaag cggatgaatt catgaggatt
      121 ttttgcatac tgtctctact atacttaggt cactaagaaa aaggagtgat ttattatgaa
      181 aaagaacatg attgggacat tattactttc aacacttctt ctaggcggct tggcaacacc
      241 agcttttgct gagggtcaag cgacttcaaa aggagatatt acctttactg aaccaacaaa
      301 taccgtggag cctcttaacc ctactgatcc ttcaaaacca gtagagccag cagatccgga
      361 aaatccagca actggccaga caggtccttt aacactggat gtagttcccg aattgccatt
      421 tggtacacac gagattgaaa gcggaacaaa aacgtatcaa gtagacgctt caaaaaacga
      481 tacaccttat ctccaagtat cagatcgtcg aggtgtaggt gcagatggcc aagcacaagg
      541 gtggaacgtg acagtttcgg tttcagattt tgtaaacggt tcacaagttt tgcaaggcgc
      601 tgaattagat tttggaacat ccactgttaa aagtacgtca gataacgaat ccactggacc
      661 aactagtcaa actgtaactg ggttgagtaa agcaagtgca gcgacaccaa tatttacagc
      721 agcaaaagat caaggtctgg gaacatggct ttctgtttat gatccagcaa atatcacact
      781 gaaagtgccg aaagcagcag ctggaacatt cacggctgat ttgacttgga acctcgtggc
      841 tggcccagta gcatagagta tgaaataaat tcaacaaact gcggtgaaaa tactataggt
      901 gaaggatttt ttaccgcagt ttttgttgaa aggatgtggt ggacaatgaa tcaaagtaaa
      961 cgactgtttg tttcgttttt ttctatttta agtctatttt tcatttttcc gtcaatcagc
     1021 caagcaaagg attcagcagg agactttgga atcaaaccgg tatttccaga gaaccaaata
     1081 gataaagcaa tcggttattt tgatttatta gtggcaccgg aacaaaatca gacactagaa
     1141 gtaattatca gcaattcttc agatgaagaa cgaacatttg aggtctctgt caatccggcg
     1201 gtaacgagtg atggtggaac gatcgattat agtcaaaaaa acccaacgtt agatgagaca
     1261 ttgccgtttg atgtccgtga cgttttgctc attgcgaaaa aggaaatcaa tgtatcagca
     1321 catgcagaaa caactgtacc tatagaagtg aaaatcccag caaaaagctt taagggacgt
     1381 gtattagcgg gtattcatgt ttcacctaaa gaagaagctg aaacagaaaa tgctacagaa
     1441 ggagcacaaa tcaaaaatcg tattgcttat aatctcgcag tcgttttaca agaaagtcaa
     1501 gagacgatag aaccggatct gaaactttta tcaggagatt tggacgaggt caacgcaaag
     1561 ccaactgttc agcttcgttt ccaaaatcct cagcctagga ttatcagcaa tttgatattt
     1621 acgagcaaga tcttttatga aaatcagctt tatattgaaa atacgtctaa tgcattttta
     1681 gttgcaccaa attcgaattt tcacttgaat cttgatttag ctggtgataa agcaaaagcc
     1741 ggcgattacc gcgcagaaat catagcaaaa tcaggcgaca gtaatgaatg gcgatttaca
     1801 caaaacttta cgatcaaaaa agaaaaagca caaaaagtaa atgaaaattc cgtttttgca
     1861 gtacaagaac aatctttccc atggctttat gcaggattgg ttgctgcagt tctagtgtta
     1921 tggttgattt tgctgttttt gtgggtccac aagaaaaaga aaaaaggaga aacaacatga
     1981 tgaggtgatt tcgttgaaaa catcgatctt attgggaggg attattgcaa gtttgctgtt
     2041 cttcagctgg caagagccag tccaagcaga taccaaaagt tcaggtacga ttacatttta
     2101 tgatctaagt ccaattccgc atccaagtgg ttcagtcaat ggcgcatcaa aacagcagac
     2161 acagctaccg atttataaag aatctaatca acatggcgta ttcccggaga cgaatgaaca
     2221 aaagatccgt tttctttatt tgatcattgg tatagaatta tggcttcttg cgtggttgtt
     2281 gttatggaga agaaaggaaa aggaggatga acatgttgct acaaaataaa ttttcatttt
     2341 ttcgctcctt cttttttact tcgctttttg ttttaagtat atttatcttt tcaccttcgg
     2401 cagaagctgt tggagcaacg cctcctgcca tttcttatga tccatacacg tatgaaaata
     2461 tcgtacctcc aaatggtgga cgtagtgcag tcaatggcgg gaagcttgtc caactaactg
     2521 gggctaacca attgcctaaa ttgactgcta cttatttgaa cgatggttca aatgatcctt
     2581 ggaaaggtgg cacggtccgt tttcattggg aaagccatgt gaaactaaca aatgtacttg
     2641 atttggtgaa tatcactgca caaggatttg catttgtggc gatcatcaat ttgccggaac
     2701 atgtatcaag cagtgatgta ttaaaagcaa ttgactggaa caacgcctac ttgtatattg
     2761 ccggtgcccc catcaaggtt actagcggaa gtttattatc agcaggaagc cataccttgc
     2821 gttttgggat ggggtcgtgg gatacaaata ctctattgac agatattatt gctattatta
     2881 cgcgaggcga attcaacgtg gacgatatcc cgcttcaatt tgatgttaca gctaatgtcg
     2941 cgaagatgac agaaaacgga gataaatatg atacgagtcc aaacaaaatt ttgaccaagg
     3001 gtaaattaca accttctatg tctaaaaagg ccgttttttc tgttgatttt tatgattcga
     3061 ataatattat ccaagatcgt atgttcaatt cgattttagc tccagctgca ggtagatttt
     3121 atcctaaatt aactggcgga aacttgaatc caggagcata tgcattttct gcaagtgcag
     3181 agataaatac gtggaatagt tacatctcac caagtgattc aacaggaaaa tataatacat
     3241 ttgctgatac cacagaatac gtggatggaa ataaccagaa ccttccaggc tctaccaata
     3301 gtcggacatt gacgatgggg ctgactgaag gacgttttga tcagttgcca tttagtcgct
     3361 ttgatcgcgt agtcaactat tttacaggaa aaaacgttac acaaggagca atactgactc
     3421 atactccagc aagcacaagt ggattgaatc agacagccaa tatcgtgtac agtgggaaag
     3481 atgcgcaagg cggattgctt tctcctgttg ctttaaaggt attggagcag tacaagctag
     3541 acggaacggt tttaccaaca aacttaacag ccgatagtca gtggggaaag ctcctttctt
     3601 ctgcatcgta ccaagtcacg gccaattggt cagcaactga actaaaaaag ggttcgatcc
     3661 attacaggct ttattcgaaa ggaacccaaa aattagcgac aggatggaca gatcaacttt
     3721 tccaaacgat ccaatcaaat aacgggggtg taaatacagc tacttctaca ctacctgcat
     3781 tggcttcagg gcaatattat tttgattatc gcttggtgga cgatgtactt actaacatgt
     3841 atccgtcttt tgcgtacaaa tggcagtctg aacaagctgg aatcaccact cttcctcaaa
     3901 taacagtggc taattttcca tctgtgagtg cagatagtca gctaaaaaac cttagcagac
     3961 aacctgagac aggagatccc ctgtctgctc tatcaggaga tacgattcaa gaaaatgtga
     4021 cattcacgtt aacaaaatct ggggatgcga taaccgacaa aaaaatcacg atctcacttc
     4081 ctgaaaatac tacttatatc aatggttcct taaaattaaa tggtacaact atcgcagata
     4141 ccggcattca acaaggagtt tctgtcccag cagatctatt gagcaaaata ggagatacca
     4201 ttcatcttac ttacaactat caattaaata ctgtagatac ttctttacaa tccgtcagca
     4261 tactgacaaa ggcagctgta ctttccagca atattacatt agcagatggt gctaagcttc
     4321 ctaacccagt tgtccaaaca tctgctaaaa caattcttgt ccccaaacaa gaattaacat
     4381 tagttaatgt accagatgat tttacatttg gtaacgatct ccccaaaccg ttgaagacaa
     4441 gttattatga atcaaaaggc gatttttctt ttgatgtgcg ggatactcgg cttccaagca
     4501 cgtctccttg gcaactgaca ggtacattga cttctttatt taagaatgat caaggtcaag
     4561 aattaagcgg aacaaaatta tacttcaatc attctggatc aaagcaattg attcagcaag
     4621 gtcaaaacac gttgatttat gagagtgatg gaacagctaa aggagaggtt ctcgttgact
     4681 ttcccgatac cgatggttta ctcttagagg taaatagcag tacgaatgct caacctggcg
     4741 caacgtatca aggcatggtc acatggaaac tgacagctgg gccaaccagc taagtgatta
     4801 gaatttgtat ggatctgtga taactgtcac agatcctctt tttcaaggat gagaaggaaa
     4861 cttctgctgt taaaatcaga aatgcttgaa ggagtggact tggaactttt cagtttgctt
     4921 gaaaaaaatg aacaacggca aatcaaactt ttccaacttt tattagagga aaaaggagag
     4981 gtttccgtta ataacgtact tacccgctta tcagttgatc gggctacctt gaaagaagat
     5041 ctgttttatt tacaagctaa cttggaaaat atcaaacaat tggaaattgt tatccaagaa
     5101 gggaatattt tattaatcag acatggaaat atagcagcag tcgatgttta ttatcattgt
     5161 tacttgcgct attctacaaa atatcagata cttctttatc tgttggaaaa tggctcattt
     5221 gatcggcaga aacttgtcat ggaacttaat atcagttcgg ctactttgtc tcgcagagtg
     5281 aaggaattaa atgattcttt aaatgagttt catctgaaaa taaaaagcgg gcggctgacc
     5341 ggtccagaaa gtcaaattcg ttatttttat ttccaattat tttggtttgg acgtccctat
     5401 cttgaaaaca aaaaagaata cagtgattta tcaggaaaca cttttttaga tctgctgcaa
     5461 aaagagttta gttttgctat tacagaagaa ggacgattga aatttgaaat atggctttcc
     5521 attatgaaga agcgaatgcg ctgtacgaaa aaatccaaac cagattatag caatcttcct
     5581 gttggattgt ttcaaacgac acaattttta ttggacctcc atacattttt gacccgttac
     5641 ttctttcaat atgcctttcc ttggaatcaa aatgaaacgt tggtttttta tcttttcatg
     5701 atcagtaact ttacattaga tacacataac tcgcatgtcc aggagttttt gataagcgaa
     5761 aaatacaaag acgacgtagt agctcaattg aatcgaacgt ttaaacaatc gatagaagaa
     5821 tatttctctt tttatgtttt tccagaagag atttcgcaaa agattgcgtt gacagtgatg
     5881 caaaatcacg ctcattttgc ctattttaga ggatggatga atatttttgg ccaagaagga
     5941 ttaaaacagc ggttaactga agtagaagat aaacaattcc tggttttatg tgaaagattg
     6001 gtcagacaaa catttgctat tgttgatttt actgaagtag acgaggaaaa tgcccgcttt
     6061 gaattatttg ctcgctatgc atctatttta cggacgctga tcaagcagtt agaattacgt
     6121 ctgcaaattg cttatgatct tccttatgaa aggctaatgg cggatatcgt gaaagaaatc
     6181 atccaggaac aattgctgaa tacgatcaaa tatgatttag tcgaatacga gaaagaaaag
     6241 cagtatgata tcattttgac tagccaattg aaagagtacc cgtcacagaa gtccgctaaa
     6301 gtttttgtat tcactagcaa cgaatataat tatgatttcc cctatttgaa ccaattttta
     6361 aaagaatgtt atttagaaaa attgaattta aggatgaata aaacatgaaa atcgtgatca
     6421 ttggtgcttc ccatgcaggc atcacagctg ccctaaatct aagaaaactt caaccgaaag
     6481 cagaagtttt actgatcgat gaagatcata aagatggact aggctatgtt tcaaatggaa
     6541 tcaaccttta tttaaaagga aagatacgta gtttagctga agttgcccat aacatgcgga
     6601 ctcttcaaga aagtggggca aaactgatca ccgaatggag agtaactgaa cttgatccag
     6661 acaaacatca gctcatcctc gcatccaaag aaggaaaaaa cgagaccata acctatgata
     6721 aattaatcgt agcgacaggt tcctctcctg tcaccttgta taaacaaatt gaagctgaaa
     6781 atgtctacac ctataaaaat ctagtgcaat ctaagcaagt acttgccgct ttaaaagaag
     6841 caaaagaagt agtgatcttc ggtgctggtt acattggatt ggaattagca gatgctttga
     6901 gaaataaagg atacattatt catctagttg attatatgcc gaatgtttta tcaagatatt
     6961 tcgataagga tatgatcaac agttttcaaa atcagctgca aactaagcaa ataaattttt
     7021 atccaaatga attcttgatc gattggaaaa aatcagaaga gaaagtagta tccgtacaac
     7081 ttctgtctca aacaataaag gcagatatgg tcattttttc tgcccaaact cgtcctaata
     7141 cgacattgtt aaaagaaaaa gtggctttgt atgaggatga gactgtgata gtcaatgaat
     7201 atctgcagac aagtgatccg gacatctatg cgattggaga tatcgtccca gtcagttttg
     7261 acaaaaataa acggcatctc tttttacctt tagttactcg agctgtacat atggcaagag
     7321 cagtagcgct aactttgagt ggtcagccaa ccgcttacga cctcagacaa aagataacag
     7381 cagcagtcat tatagactac tttttaggaa ctgtagggct gacagaagat gaagcgccat
     7441 tcttggaaca aaataccggt tcgtgttcag gagaatttga tctatttcca caatacgacg
     7501 aagaaaacaa aacagtaaat gcaaagctga tctaccatcc ggatacatta gaaataattg
     7561 gcggacagct gataagccaa gaattcttat tatcagattt gaacctgctt gcggatatcg
     7621 tgaaacacaa aactacgatt ccacagctag cagttgagga ttttggattt ctgtctgaat
     7681 acacctctcg ttttcactac ctcaatgagt tagcttttaa agtactagct aagagagcaa
     7741 atagcaatag agtagataaa agactgtgag aaatatcacg gtcttttatt gtgtggggat
     7801 ataataaata ttaatcaatc gagaataaaa aattcatata atgaaatagc ggaagaattt
     7861 tttgagcata atattcgcca aaaatttatc aagtgataaa attgttgtat aaaatgatta
     7921 tttcaggagg aggagttaaa tgtttttagc attaaatgaa attatgcatt caaagttacg
     7981 ttatgcgtta gttgcagggg tgatgttttt gatcgcctac ctggtatttt ttttgactgg
     8041 gttagcttat ggcttagctc aagataatcg aacagcagtc gacaagtggg aggcagattc
     8101 gattgtgctt tcgaaagatg caaattcaaa tctagggatg tccatgatta ctaagaagat
     8161 agcagaagaa gtcgaaggtg ggaaagtggc gtatcttgcc caaacacctg gagtcgtgac
     8221 tagtaaagac agtacagaag aaggaaaaat caatgttagc ttcttcggta tcgataaaaa
     8281 tcaattcatc atgcccaatc ttgttgaagg aaaagctttt gataacgatg atgaggcagt
     8341 aggcgatatt agtttgaaag aagaatatgg tctagccata ggagatacag ttaagttatc
     8401 tggtagtgac aagacgttta aactaactgg ctttacggat catgccaaat tcaatgtctc
     8461 accagttctc tatacaacca tcaatgctta ccaagaaatc cgcttcgaaa aagaagatac
     8521 aagtgaaaat gcacggatta acgcaatagt tgtcagaggt aaaatcagta atttacctga
     8581 agatttagaa cagatcaaaa tttctaaatt catcaatgaa ttacctggat ataatgcgca
     8641 agtattgact tttggattta tgatcggatt tttgatcgtt attgcggcta ttgtgatcgg
     8701 gattttcatt tatgtactga cgatgcaaaa gattaatatc tttggtgtaa tgaaagcaca
     8761 agggatcaca ggaggattta ttgcgcgttc tgtagtggca caaacattca ttttatcatt
     8821 tgttggtatt cttcttggtc tattaggaac agtgggaaca tcccttgttc tacctgatgc
     8881 ggttccattc caaagcaatt ggctgttttt tggcgtcatt agcttgttga tgttagtagt
     8941 agctgtgtta ggcgcactat tttctgttcg gacaatcgta aaaatcgatc cgttgaaggc
     9001 aattggataa gaaggaggaa gaacatgaaa gcaatagaat ttaaagaagt agaaaaaagt
     9061 ttccaagatg gcgaccaagt agttaaagca ttgaaagaaa caaccatgag tatcgataaa
     9121 ggggaatttg ttgcaatcat cggtccttct ggttcaggta aaagtacttt tttgactttg
     9181 gcaggcggat tgcagacgcc tagcagtggc tctgtattta tcaatgatca agaattcagt
     9241 aatcaaaaag aaagcgaacg cgttaaacta cgttttaaag aaattggctt tattttgcaa
     9301 gcttccaatc tggttccttt tctgacagta aaaaagcagt tattattagt agataagatt
     9361 aaacatgaac atcgtcaaaa agaagcaaac gaattatttg agcagcttgg cgtggataag
     9421 ttgatcaaca agtatccaga agaactatct ggtggagaac ggcaaagggt cgcaatcgct
     9481 cgtgcattgt acaatgatcc gtccattatt ctagcagatg aaccaactgc tagtttggat
     9541 tcagaaaagg cacgagaagt agtcgatatc ttggcaaaag aatcaaaaga caaaaataaa
     9601 gcaacgatca tggttactca cgatacacgg ctgattgaca aatgcgatag aatatttatg
     9661 atggaagatg gtgtattgaa agaaaaagaa taaccaaaaa gcaggtggaa aaatggtcca
     9721 tcgatacaac aaagatacac agcaaaaaat tttgaaagaa gcgactgact tgtttatgtc
     9781 caagggatat ctcggcactt caacaagaga aatcgcacaa aaagttggga tcacccagcc
     9841 caatctctat cattatttcg gtgataaaga aaaactatat acggcagttt tagaaaacca
     9901 cttaaaagat gttggaaaag ctttgagaga aatcgttcaa acaagcgaaa cgggatttca
     9961 agtaaccttg acaaaaatgg cgcagttttt gattgagaca catctggtcg atttgtttct
    10021 gatgcttcac gatcttgaaa gcaatctttc aaaggaaaca agagatcatc ttttctttct
    10081 atggaagaaa aattatcgtg aaccttttga agaaatcttt tcagcaaacc aatctgtgct
    10141 aagaaatggg atttcaaaag aaatcgcagc aaggcatttt ttcttagtgt tagcacctta
    10201 catcactcgg tcgaaaagac ctgtggaaga accgctaaat gtggcgcaat tgatcgattt
    10261 atatttgaat ggtgtattag gagaagcgta aagctgttat atagggagaa aatagttagg
    10321 tgaagaagca agatatgacg aagatcgtta tatcttgctt ctttatatag gtagtttttc
    10381 ataaagacaa atttgttatt ctctcatgat tatcagggta tatttttatt tattatgtcg
    10441 gtgttccagg aagtgtttta atttaataac gaagaaatta attgtttgta gaatgaagga
    10501 aactatttat tgggtagatg aatcaccacg aatagtcaaa aggagatttc aggatatgcc
    10561 aaaaatgaaa aaaatcattt tagcagtaat gttattttct acggttatat cttttacagc
    10621 cccttttttg cttacttaag ctgattttaa gttttggccc ttagtctgga tctacgaggt
    10681 gagagtcaag aatgaaaaaa ataattggag cttttgtatt tgcaatcatt atcattatta
    10741 tctgttttca aatagatgtt tttggtcaaa aaaagatagt tggacaaacg gtcagcagta
    10801 cgaacagtac ggttacaaag acaaaggaat catttgatga tacagaacaa gagacattaa
    10861 tcaaaatcgg aaaaaatgac cgtacactat atacagatga ctcgctaact accccacttg
    10921 caactataaa cggcggagag ctggcggagt ttctttctga aacaaaaaat gcttatcaga
    10981 tcaagacaaa tgatggctat actggatatt tagccctcga agatggaacc aaagtcacaa
    11041 agaatataca aacaaaaccg gaagagctat ctgatgcagt gattgtatta gatcctgggc
    11101 atggcggaaa tgatactggg gcattaagca atgatgaaca aacagaagaa aaagatataa
    11161 cattaagtac agccataaaa gtaaaaaagg cgctagagga tgctggagca acggtttatt
    11221 tgacccatac tacagatgaa ttagtacagc ttggagatat atgcgactac agtgaagaaa
    11281 aaaaggcaga tgtctttatc agtttacacg cagactctac ggaatatgcg aatgaagcaa
    11341 ctggaatcac gacatattat tactatggac aagaggaaac attagcacag acaattgctg
    11401 actccttcac tgatctgcct ctggattcaa gaggaatctc cactgggaac tatcaagttc
    11461 ttcgagaaaa tcttcaacct tctattttaa tcgagatggg ttatatgaat aatgatagtg
    11521 atttaaagga attagtaaca gacagttatc agcagcagat tgctgcaagt ttgacacaag
    11581 cattgaccac ttattttcag taataaataa gcccagccaa acaaaaatag ctcctcatat
    11641 ttttcgtttg gccgggctta ttatcgcaga tgcaagcttt tgaacaccgt ttattttttt
    11701 agtagcttca aagctttttc tgtatttgca aagtgaagtt tggcatattt ttcaagcata
    11761 ggcatgccgc ctttctccaa tagttttgcc gctacttggt cagatttcgt tccagctcct
    11821 gatggaaggg tgattccagc ttcagctgat gctttgtgta actcttccaa aaagctggca
    11881 cgactgatga tagaagcagc agcaacagct aaatgatatt gttctccttt agtaacgaag
    11941 tacagttttt cttgtaattg atttttttct aaacgcgcat attttttaaa atttgcttcc
    12001 ggcgtaaact gatcgatcaa aatcgcttct ggtttttctg gctcgatttt ttttagcagc
    12061 aaatggatcg cttgattgtg caaagcgact ttcatccgaa cggcattgta ttttggttgg
    12121 atctcattgt atttttctgg agataagaca agcagtttat aggggatggt tttttttaag
    12181 atgtcagcaa gctggatgat ttggctatct tttaactctt ttgaatctct aacaccaagt
    12241 ttacgtaatt ctgcaagctg atcacgtttc acataagcag cacatactgt tagcggaccg
    12301 aaatagctgc catttccgac ctcatcacta cctaaaacgg ataattgact gatatttttt
    12361 ggcaaagaag aggctgtttt tgctggcttg gcttgtttat cctgtgcctc cccccattta
    12421 tcagcttcta ttgctgcatt cgtaccttga aacatcactt ttccggatgt ataagcggta
    12481 atggtcgtcc cgtctttttt tgcagcaaag ctagtataag gaatctgttt atttaacaaa
    12541 taagagcgat agtatgcttt catttgacta agttggtcgt ttgttgcttt gataatgacg
    12601 ttgctcataa aattctcctc gtttttatac ataaaactat accgcaactc acgacttttc
    12661 gttttctaag agattgcgag acatagcatt tttttaaagt ttatcatata atagttaagt
    12721 atgtgaaaaa tatttgtgga gaacggtgaa agaaccaact tcatggtaca ctaaataaaa
    12781 ctttcatcaa ataggaggaa atgattcgta tggcgcacga aaaaacacgc tacaaagcgg
    12841 tgattgccaa ccaaacatat actattatcg gacgggaaac caagcatcat atggatatcg
    12901 taacgaagct gatcaatgaa cagttagcag aattgaaaca attatcacca caaatggata
    12961 atgaacaagc agcaatcttg atggctgtca atgcgctttc ggatcaattg aagaaacaag
    13021 aaagaatctt ggagctggaa gaagaaacag cagaattaaa gaaaaaaatg atcaaattta
    13081 cagagcttga aaatcgtgtg aaacgcattg aagcaatcga gaacgaagct cgggaagtat
    13141 tgaaagaaaa tggtcaagca gatcatacca ttaaaaatca tgtggaagca caacagattt
    13201 taaacgagaa acgaaaagga caaattaaac aaaaatcttc taattaagat ccttttatca
    13261 aaataagaaa aatttaaaaa aagttagaag agaaaggaac gtagcatgct gagtttgctg
    13321 attttatttt tattgctaat tgcgtttttt tctggagcac gtcgcgggtt tgctttgcaa
    13381 atcatattcg cgattggata tgtattgtca tttattgctg cccagcattt ttacaaacca
    13441 ttagcaagtc atttggaatt atacattcca tacccagctg tcacgccaac atcaaagtta
    13501 gcattttttg atcaggtatt tgcctttcac ctagatgaag ctttttatgc aggaactgct
    13561 tttctgatta ttttgctaat tggctggctg cttacccgat ttgtgggggt ttttgtccat
    13621 ggattgacgt atgtgccgat cttgagacag gtagactgga ttgcaggagg catcctgtca
    13681 ctaatcatgg cttacgttac tatatttttg attttgcagt tacttgcctt tgttccatta
    13741 gatgtggtcc aaaatcaatt cggcgagcat agtttcgctc gctttatcgt tgagagaacg
    13801 ccatttctta ccaacaagat gtatgagctt tgggtaacga atattttgaa ttaaggaaaa
    13861 tagtgctgga aaatatttcg ttttttgtac agagtagatt atttaagaag gctgcgtagc
    13921 gtatgtccgg cacagctctt ttttcatagt gaaagataag gtgataaaat gaataaccga
    13981 atccttgaaa cattggaatt tgaaaaagtc aaacagatgg tcagacaatt tgtagtgact
    14041 gcacaaggaa aagaagaact ggcagaattg gtaccagtga gcgaggaaca aacgatcaca
    14101 aactggcttc aagaaactga ggatggattg aaagtgcaac gtctgcgagg cgggatccct
    14161 atacctaaac ttgaaaatat ccgtccccat atgaaacgga ttgagatcgg agcagacttg
    14221 aatggagtgg agcttgcaca agtttccaga gtattgtcta cgacaagcga attgaatcgt
    14281 ttcattgatg atctttatga cagtgaaatc gaatttgcac gtttgtatat gtgggcagat
    14341 cagttagtca cgatccctgt tttgagccgc cgtttaaagg aagcaatcga tgaagacgga
    14401 cgcgtgactg atgacgcttc tcctgagtta aagagcataa gacagaacat tcggcgaagt
    14461 gaacaagctg ttcgtgaaca gttagatggg atcgtccgtg ggaaaaatgc aaagtattta
    14521 agtgatgcga tcatcaccat gcgaaatgac cgctacgtta tcccagtcaa acaagaatac
    14581 cgcggtgtat ttggcggtgt agtccacgat caaagtgctt caggacagac tttatttatt
    14641 gaaccaaaac aagtggtgga tttgaataat cgtttgcgtc aataccaaat cgctgaacga
    14701 aatgagattc aacgtatttt aagtgaactt tctgctgaac ttgttcccca tcgtcaagaa
    14761 atcatccaca atgcttatgt gattggtaaa atggatctga tgaatgcaaa agcacgattt
    14821 ggtaaagaag taaaagctat cgtgccggga atcagtgaag acaatcatgt cgtcttgaaa
    14881 caagcaagac atccactgat cgatcaggaa aaagtagttt ctaatgacat cacaatcgga
    14941 aaagactatc aagccatcgt cattacagga cctaacacag gtgggaaaac gatcacgttg
    15001 aagactttag gtctgttaca actgatgggg caagcaggat taccgattcc tgcaggtgaa
    15061 gaaagtcaaa tcggtatttt tgaggaagta tttgcggata taggagacga acagtcgatt
    15121 gagcaaagtc tatcgacctt ttcttctcat atgacgaaca ctgtagatat tttatcaaaa
    15181 gtcaatgaaa aaagtctggt attatttgac gagctcggtg caggaacaga tccgcaagaa
    15241 ggtgctgctc tagcaatcgc aatcttagat gatcttggta aaaagtctgc ttatgtgatg
    15301 gcaacaacgc attatcctga attgaaagtt tatggatata atcgggcaaa tacgattaat
    15361 gccagcatgg agtttgatgt ggatacatta agtccaacgt atcgtttgct gattggcgtt
    15421 cctggacgaa gcaatgcgtt tgaaatctct agccgattag gtcttgatac agaagttatt
    15481 gatgaagcga agcagttgat gaatgatgag agccaagatt taaacgaaat gatcacagat
    15541 ttagagaatc gccggaaaat ggcagagacc gaatatctgg aaatgcgtca ttttgtttct
    15601 gaggcacaag aacttcacga tgatttgaaa gaagcttaca gctatttctt tgaagaacgt
    15661 gaaaaagaaa tggaaaaagc aaagaaaaaa gcaaatgaag tcgtgtcaga ggcggaagaa
    15721 aaagcagaaa aaatcattgc tgatattcgt aaaatgcaac agcagattgg gcaaggaaat
    15781 gtgaaagagc atcagttgat cgatgcaaag acccaattag caaatctaca tcaagaagaa
    15841 actttgaaga aaaataaagt attgaagaag gcgaaagaac aaaaaacgtt gaaaccggga
    15901 gacgaagtgt tggttacgac ttacggccaa agagggacgc ttttacgtaa aaacgggaat
    15961 cagtggcaag tagaaatcgg tatattaaaa atgaatgtgt ccgaagacga gctgacgcct
    16021 gttgctcctc aaaaagagcc gacacaacga gttatccatg ctgtacgatc tgaatctagt
    16081 agtcacgtgc cgaatcaatt ggaccttcga ggaaaacgat acgaagaagc gctaagtgag
    16141 gtagatcaat atttggattc tgccattcta gctggttatc ctcaagtgac tattgtccac
    16201 ggaaaaggaa caggcgcact tcgcaaggga attactgatt atcttaaaaa ccatcggagc
    16261 gtcaaaagct ttgagtttgc accggcaaac caaggcggaa atggtgcgac aattgttaaa
    16321 tttaagtaaa gcttactaaa ggtaagcaga tggttcgcta tccaagtata gaaatgctat
    16381 actagtcata gattttaaaa atggaggtct ttgatatgtc acaagtaatt acagataaga
    16441 catttaatga agaaacagat aaaggacttg tattgattga tttttgggca acttggtgtg
    16501 gtccatgtcg tatgcaagca ccgattttgg atcagttgga acaagaatat gatgaagaag
    16561 aattcagaat tgctaaaatg gatgtggatg aaaatccaga aactcctcaa caattcggta
    16621 tcatgagcat tccaacatta atgttgaaaa aagatggtca agtagtagaa aaagctgttg
    16681 gtgttcattc aaaagaacaa ctacgtcaaa tgatcgatca atatttataa aaacttacag
    16741 caaaaataag ctgagggtgg gactgaatcc agttccgtcc tcggtttttt tgcggttgag
    16801 ttaaggttat tcaaattaat attttttgag tataattacg ttgtcaggct ggattgtttt
    16861 tttgacagac atgctataat aactttaatt gaatatgaag gggagtacca gatgaacgaa
    16921 cgaatcaaaa acaaattagc tttacttcct gatcagcccg gctgttactt gatgaaagat
    16981 aaaaatggaa cgatcattta tgtcggcaaa gccaaaatat taaaaaatcg tgtccgctca
    17041 tattttactg gtagccataa tacgaaaacg gaacggcttg ttagtgaaat cgaagacttt
    17101 gaatacatcg ttacagaatc gaatatcgaa gcattgctct tagagatcaa tctgataaag
    17161 aaaaatgatc ctaaatacaa cattatgtta aaggatgata aaacctatcc tttccttaag
    17221 ataacgaatg aaaaatatcc ccgtttggtg attactcgta aggtactaaa agacaaagca
    17281 ctgtattttg gaccatatcc cgatgtcggt gcggcgaatg agacaaagaa gatcctcgat
    17341 cgattatttc ctctgagaaa atgcaaacct agtcagacga aggagccttg tctttactat
    17401 catttgggac aatgtctgtg tccttattat ttcgacgtag atccgaaagt ctatacgaaa
    17461 atcgttgatg aagtgaaaaa ctttttaaac ggaggacacg aaaaaatcga gtcagagatc
    17521 catcagaaaa tggaaaaagc tgctgaaaac atggagtttg aaaaagctgc agaataccga
    17581 gaccagatcc gtgccattga gacaatcatg actcgccaaa aaatgacaaa tactgattta
    17641 ctggatcgag atgtatttgg ttatgcgatt gataaaggat ggatgtgtgt ccaagtgttt
    17701 ttcgtaagac aaggaaagct aattgaacga gatgtttcaa tgtttccttt ctataacgaa
    17761 gcagaagaag atttcttgac ttacctcggt cagttttatc aggaaaatga gcatttcatt
    17821 cctaaagaag tcttgattcc tgatacgatc gacaagccca gtgtagaagc tttgttagct
    17881 acgaaagtgc tgcaaccaaa acgaggagaa aagaaaaaat tagttgaatt ggcgagtaag
    17941 aatgcctcag ttgctttgaa tgaacggttt gatctgattg ccagaaaaca ggaacggacg
    18001 atcggagcag ttgaacgttt aggaaacgcg atgaatatcc cgaccccaat acgtatcgag
    18061 tcttttgata actctaatat catggggacg aatcctgtgg ctgcgatggt cgtattcatt
    18121 gatggaaaac cggcaagaaa agaatatcgg aaatataaaa taaaaacagt caacggaccg
    18181 gatgattatg catcaatgag agaagtcatc tatcgcagat attcgcgagt gattcgcgaa
    18241 gggttgcctt tacctgattt gatcttgatc gatggaggaa aaggacaagt agatgtggca
    18301 aaagatgtct tagaaaatca attaggaatc gatattccta ttgctggcat ggcaaaaaac
    18361 gataaacata aaacaaatga gttgctattc ggtacagatt tggctgtagt accgcttgag
    18421 cgaaattcac cagagttttt cttactccag cgaatccaag atgaagtcca tcgattcgca
    18481 atcactttcc atcggcagct acgcagtaaa aacagttttg cttcccgatt agatgaaatt
    18541 gaagggttag gaccaaaacg aaaaaaaatg ctgcttaaag agttcaaatc gttgaaaaat
    18601 atcacagcag ccacgacaga agaattacaa gaaatcggac tgccgaaaaa tgtcgcacaa
    18661 aacgtatttg ataaattaca tcaggaatga ggaaagggca ctttacaaag aaagtaaagt
    18721 gtcctatcat tttatgtaca acaaaaagag cgtttacgtt ttgttggtaa ataataaatc
    18781 gcttacgtct ggtgtctaag gatatatgtg atttcttgaa gaaggagtga agaaatgtta
    18841 gaagtcaagg atcttgttaa aacttttggg aactacacag ctgtcgatca tgtctctttc
    18901 caaatccccg atggaaaaat catggggcta attggccaaa acggggctgg gaagacaacg
    18961 acttttcgtt tgatcttgga ttttttgaca caagaccaag gagaagtgtt atggaatggc
    19021 catcatcttg gggagaaaga ttatgatgtc atcggttatc ttccggagga acggggactt
    19081 tatccgaaag taacgattca agaccaactg ctttattttg cagaacttag agggaaatca
    19141 agaaaagaga ttgaaccaaa aatcgacttt tggatggaaa aatttcaggt aaaagggaaa
    19201 aagacggata aagtaaaatc tttgtctaaa ggaaatcagc aaaaagtcca gctgatcgcc
    19261 acgttaatcc atgaacctaa attgatcatt ttggatgagc cattcagcgg gttagatccg
    19321 gtaaatgctg aattgctaaa agatggaata ttggaattga aaaaacatgg ttcatgtgtc
    19381 attttttcta gccacaatat ggataatgta gaaaaaatct gcgatcattt gatcatgttg
    19441 cgaaacggaa aaatggtttt gaatggaaaa gtacatgaga ttcgtgaatc atttggccgt
    19501 acgaagttat tcttggaatc tggtttaagc caacaggaag tagaagaaat cgaaggcgtg
    19561 aaaaaagtga tccttcatga agacaatacg ttagagatta ccttagaaga tcctgaagct
    19621 gggaaagaaa tctttactcg tgcgactcag ttcggctaca ttcctatgtt taaccagcaa
    19681 ccgccaactt tggaagagat tttcaaattg aaagcaggtg aaatcgatgc gtaagttttg
    19741 gattattacc aaagatgtct atttaaaaaa tgttaagtcg atttctttct tgatcatgat
    19801 attagtccct tttatcatgc tgggtatcat ttatgtagca ggaaactttg ctcaacaaaa
    19861 tagtgatgtc aataaaatcg gcgtattggc tgataatgag caaatcagtc agcaaatgag
    19921 ccaagtcaaa acagatgatt ttgagttcaa agcagttgat tctgaagaaa aagcacaaaa
    19981 agagctttcg gaagaaaaaa tcgatgcgta tttagtagtc tcaactgaga atgataagat
    20041 aaatgggatg ctttatagcg aaaattcatt aggacaaagt acacaactac tgatacaaca
    20101 acaactgact ggcttgcaat cgatgcttcg agcgagtcaa ttaggcattt caccagaaga
    20161 agtagctagc ttgagccaac aagcaagttt gactcgacaa aaagtcaatt ttgattcaaa
    20221 aggaaaaatg acagtcggag aagataactc gacagtccaa tacgtcgtaa gttatgtagc
    20281 aacgattgtc ttgttcatta ttattttgac gtatgcgcag atcattgcac aagagatcgc
    20341 ttctgaaaaa ggcacgcgga tcatggaagt gatcctgtcc agtacgactg cacaaaagca
    20401 tttttacgga aaattaacag gtgttttact tgttgcatta acgcaaatgg cattatacgg
    20461 tattattttt ggtataggat acagtcaatt caaagatatg gaaatggtca aaaatatatt
    20521 agacggtatc tcattggata acttgattgg accattcttg tggtattctc ttctattcat
    20581 gatctttggc attttgattt tttctgtttt agcagcttta tgtggctctt tggtcaacaa
    20641 agcagaagat acagcaaaag caattttgcc agtgacttat ctatctctag gcggatacat
    20701 gcttggattg atactaggag cttcagatcc aaacaatatc gttattcgga tcacttcgta
    20761 tattccattc ttatcttcat atattatgcc ggttcgctta gcaaatgaga cagtcggtat
    20821 gggtggagca ttgatttcct tgttggtact tgtagccgta acattcttat tgatgatctt
    20881 gtctgcaaac atgtacaaat cgaatgtact cgtttatagc gaaggcggat tatggagttc
    20941 attgaaacaa tcgatttcaa ttatgaggaa tgaacgaaaa aaagcataaa acaatcctaa
    21001 aatacagaag gaagctggac atctattgtt cccagcttct ttttgtatag acctatttta
    21061 tttattttac tatattggat atatattcat tgaaaatagt gtataacaac tttataatat
    21121 tgagtatacc aatttttgga ggcgttttaa tggaccgtta tttagattta ctttcagaaa
    21181 aattcccctc aacggaggat gtcatcacgg aaatcatcaa tctcgaagca attttgcagc
    21241 ttccaaaagg aacagagtta tttttgagtg atatacatgg cgaatttcct gcttttgatc
    21301 atattctgcg tatcggttca ggaaatctta aagaaaagat caaagacctt ttttctgaac
    21361 aaatgacgga aacggatatc agccaattca ctatttttac ggcttatcca gaatatgcat
    21421 taacgactga ttggtacaaa gaacaagata aatcgcagct gatccatcat ttgatcgatc
    21481 ttttacggtt tacgacagtc aaatataccc ggtcaaaagt tcgaaaagga ttgccgaaag
    21541 aatatagcta tatcattgag gaactcttgt atatcgatga ccgtatcaat ggaaaaaaag
    21601 actatgtaaa aaaaatcatt gaacaacttg ttttgatgaa ggaagaagaa aaatttttaa
    21661 cgaaacttgc acagacgatc caaaaatctg tcatcgatca tttgcatatc gttggagata
    21721 tttttgaccg aggaactcaa gcagccaaag tgatggatcg aatcatggat ttttcttctg
    21781 tagatatcca atggggaaat catgatattt tgtggattgg tgcgtattgc ggctctgagg
    21841 catgtttact gacactttta cggattgcag cacgctataa ttatttattt gaattagaga
    21901 aagaatatgg gttgaattta cgtccattgt tttcttttgc tcatcaaact tatcagaaga
    21961 atccagtatt tgcgcctaaa aacagtaaaa atctatccga aagagagcaa gaagaattag
    22021 aaaaaatcca tcaggcactt tctatccttc aattcaaatc agaacatcag ttattggatc
    22081 gtcgacctga atttaaaatg gacgatcgta aattgctgga aaaaatcgac tatgaagcat
    22141 caacgattga tttagaaggt cagctctatg agttgaaagg aacttgtttt caaacgatcc
    22201 agccagatga tccaaaaaaa ttcttggaag aggaacaaaa agtgattgat agtttgatgt
    22261 attcattcca gcactctttg agaatgcaaa aacatatgac gtttttgatc gaaaaagggg
    22321 gaatgtatct cacgaacaat cagcatgtgc tgtttcatgg ctgtatacct gtagacgaga
    22381 agggacagct cttagcattt gaattagacc aatcttatcg cggaaaagaa ctgctgggct
    22441 tttttgaaaa acagataact gaaagcgcaa aagatctgac tgcaaaagaa gatttagcaa
    22501 ccgatttgat ttggtatgcg tggagtgggc cattttcgcc tttattcggc aagagtaaaa
    22561 tggcgacttt tgaacgttat tttctcacag agcctcatac gcacgtcgag aaaagcaatc
    22621 cttattatca cttgcgagat gaagagtggt tcagtgaaaa aattttagca gaattcgaca
    22681 caaaagaaga agggtcagca atcattaatg ggcacacgcc agtaaaagta aaaaaagggg
    22741 agtcaccgat caaagcaaat ggaaaagtat ttgtcattga cggaggttta tccaaagctt
    22801 atcaaaaaac gacaggaatt gccggttatt cactattatg caattcttat ggtttccaaa
    22861 tcgtgacaca ttatccgttt ttgcctattg aacaacaatt tgcaaaaaaa tccgaccaaa
    22921 caaatgtgaa aaaagtaatc gaacagcaac taccacgcaa actcaatcgt gatacaacaa
    22981 aaggtatgga actgcagcag cagattaccc agctcaaaag gctgttggac tatcgaaagg
    23041 acgattgaga agaattccag tgaacattgt tccatagact ggagactgag acaaaagtcg
    23101 tgtcgcagtc tctttttccg gataaacggt gttcttctgc caactcctcg gtcacaagtc
    23161 acactattca acaaacatga aaagctgttt tttgaaattg ctccttgtga ctcagagttg
    23221 aacggcaggc tcacgacctc ttggtataaa cggtgttcaa aagccagttt ctcggtatta
    23281 agccaaattt atgcaaaaat gtgaaaagcc attttcacaa aatttttctt aatactcgaa
    23341 actaaacagc tttttcacaa ccccctcaga aagtctatta aaattcattc acaaagaaat
    23401 cgaataagcg ctgttcagat ggatgtacac ggtgggtaag ttccggatgc cattgaacac
    23461 cgaggatttt atgcatatca tctttgcttt gaaccgcttc aatgagtcca tcgttagaaa
    23521 aagcgatggc ttttaataaa ggtgaaagat ctttgactgc ctgatgatgg taagaattca
    23581 caaaatatgg atcggggaga aggttgctta acaaactgtc tgaaacaatc ttgacttcgt
    23641 gagtcgtaaa ttgcggggca gtgggctgtt gttcatgttt tactgaccac tttggatata
    23701 atgaaagatc ttgataaagt gtaccttcca aaacgacatt caatagttgg agtccccggc
    23761 agactgcaaa aattggtttt ctttgtttca atgcttccaa gatcagtgcc tgttcaaatt
    23821 ggtctcgttg aatatttgtt tccgttagct ttggatgagg atcttccatg taaagttgtg
    23881 gactgacatc ttgaccacct gcaagaataa gtttgtcgat ttgtccaatc agttgaggag
    23941 ctgaatctgg agacatgact ggcagaataa gaggcaatcc ttgagcatct aaaactgcat
    24001 ccacgaatcc ttgcggtgta tagctcactt gatttccttg gaaagtatct gttgctcgaa
    24061 tcagttgatt tccggcaatg ccgatgattg gtttcatttg tattccccct aaagtagact
    24121 tattgtaaca aggatttaaa aaaaattaaa ctatgtaaga cttgccccta tacttatctg
    24181 ttcttgctgt gttactatct gtaaagagaa atttcgtgtg aaattcatga cgatagttga
    24241 aaatattgct taatttgtta taataaaaag taagcagaaa taaaaaggtt gggcgtaagc
    24301 ttcaaggatc tagttcttca aggggtgaga aggacatttt attgaagggg cctgcctata
    24361 ctaagttatc tttagaggta catactttca atgaaaaaag aaagcatgta cctctttttt
    24421 aaatcgaaag gaagtgaagc aagtgttaga agctttggaa caaatccgaa aagcagaaga
    24481 agaaaatgaa aagcgtgctc aaacactgcg gcagcagctg aagatctatg caacagaaaa
    24541 agagcaggaa ttggaaacga tccaaacaaa ctatcgacaa caactaaaac agttggtgga
    24601 agaaaaagaa caatttgaaa tacaagaatt agaaaaagaa aaaatgaaat tgaaagcaga
    24661 agcagacaag gtgcaagcaa ctttgaaaga tcaatatcaa aagcatcaga gtcaagcgat
    24721 cggtgcgatc attgaaaggg tgaaagaaac ttatggccgt cactaagatg gaaaaagtga
    24781 ccctcatttc agataaaaga aatcaggaga ggattttaca agcagtacaa ggaatccaaa
    24841 acgttgaaat ccgggatctg tatcaaaata gaacaaacaa ccagtgggtg gagaagtatt
    24901 ttccagatac cacgattatt gataaagaag caaaattaag cgctttaggt aatcggttga
    24961 aagacatcca agaagctatc caattcatac aacaccacgg cgatagccgt caaaagaaac
    25021 tccatttgaa acgtcaagaa ctttccttac aagatttgga agccaattat tccgaagaaa
    25081 atttcataaa taaattgaaa gaagtccttg atttaaaaga aaagtgggaa caactaactg
    25141 aagaacgtga tcgtttagaa gaagaggaag aatggcttct tcattggcaa cagctggata
    25201 ttgctccaag tatgtatgca agtaagacga ccatttttga gatggggact gtgagtgcag
    25261 caaattttga aagtttcaag gaagaactga gtaagcttga tgacgtttat atggaagaaa
    25321 tagattatac gccaaaacaa gtttatcttt cgtatgttgc tttaaaaaaa tcagttgctg
    25381 ttatagaaga aattgctggg aaatacgggt tcaataaaga aacgtatcct tatgaacaaa
    25441 atcctaaaga aaaactgcaa gagaccaagc agcaattatc cattgttcac gagcagcaaa
    25501 agaagataac gacagcgtta ggtcagtgca gtggctatat ccaagaattt gaatgggtag
    25561 aagaagtcac acttgccgtt gcagaacgag aaaaaataaa agaacggttt atccatgcga
    25621 cttatctgat cgttttgcaa ggttgggtag atgcagaaga aaaacagaat ttgctgcatg
    25681 tgttaaacga aaccgtatca gaagaagata tatacgtcag tttcgaaaca ccaaactcag
    25741 aagagattca gcaggaagtc cctactaaat tgaaaaacca tccgcttgtc gaaccttttg
    25801 aattgctgac tgaaatgtac agtctgccaa aatatgaaga agtagatcca acaccttgga
    25861 tgacaccatt ttatcttgtc ttcttcggga tgatggtcgc agatgttggt tatggtttgc
    25921 tgatgctcat tgggacaata ctagctcaaa aactacttgt tctaccacgc gggatgaaac
    25981 gtttcgtaaa attctttgag attctctcga taccatcgat catctgggga ttgatctaca
    26041 gttcattttt cggacagtca ttaccaaaag aactgtttgg catccgcttg cctttcccaa
    26101 tcctatctac gacggatgac gtcaatacga ttttgatttt atccgtgatt ttcggtctga
    26161 tacagatttt ggttggatta tttgtggcag caaaggaaaa tatcaggaga aaagattact
    26221 tgagtgctgt cagtgatgga tttgcctggc aagggatcct aattgggatc gttattgcgt
    26281 tggttggtgc catgttgata aaaaatacag catttgttta ccttggcgct gggctatcga
    26341 tcattgctgc cttatgtatc ttgatcgttc cgattatcca aacgccgtct aaagtcaaag
    26401 gtgctgccaa aggtgcgtat aatctttacg gactgaccgg ctatatcggt gatttagtca
    26461 gttatacacg tttgatggca ttgggtattt caggcggaag tattggagcg gcattcaata
    26521 tgctagttgc tttcatgccg ccagctgctc gattcagtgt agggatcctt ttgatcatcg
    26581 ctttacacgc actgaatatg tttttgacac tgctaagtgc ctatgtccat ggcgcacgat
    26641 tgcagtatgt cgaatttttt gggaagtttt atacaggagg cggacgtgcc tttgatccgc
    26701 tgaaaacggc ggaaaaatac gtcaacatca atcacaagaa aaaaaacaat aaataattgg
    26761 aggattttta tataatgatg gattacttaa ttagtcaaaa tggtggaatg gtatttgcgg
    26821 tattagcgat ggcaacagcg acgatttttt cagggatcgg ttcagctaaa ggtgttggaa
    26881 tgacaggtga ggcagcagca gcattgacaa caagtcaacc cgaaaaattc gggcaggctc
    26941 tgattctgca attgcttcca ggtacgcaag gtttgtatgg attcgttatt gcctttttga
    27001 tttttatcaa cttaggaaat gacatgtcag ttgtacaagg actgaacttt ctaggtgctt
    27061 ctctgccgat tgcttttaca ggcttgtttt caggtattgc ccaaggaaaa gtcgcagcgg
    27121 caggtattca aattttagcg aaaaaacctg aacatgctac aaaaggaatc atttttgctg
    27181 cgatggttga aacatacgcg attttaggtt tcgttatttc cttcctatta gtgttgaatg
    27241 cctaagcata aaggaggaaa agcagatgaa cgccattgaa aaaatcatct ctcagatgaa
    27301 cgaagcagca gagcaggaaa gagcggcgtt agaacaagaa gagcgaatga agatcgatca
    27361 aaactttgaa caaaaacgta cgcaagttga aacagaacat caaaaacaaa aagaaaaaca
    27421 aatcgaatta ctcgaaaaaa aataccgtca gctaaggaat cgccagcaag tagaagtacg
    27481 acaagaaaat ttgaatgcga agcaggaatt tttaagacga ttgtttgcag atgcggtaac
    27541 tgaaatggaa aattgggatg aatctgaaca aatccagttt atcaaaaatg cattgtattc
    27601 attacctttg acaggaaaag tagcattcat tgctggagaa aaatcagcag cctatctttc
    27661 tcagacgttg ttggatgaat ggaacaatga acttcccttt atgatggttt taagtgatga
    27721 aactgttgct gatcaagcgg gttttctgat aaacgatcaa ggagttcagt ataattttct
    27781 tttcagcagc cttgtacaag atatccaagg aacgatgagt tttgagattg ccaatcaatt
    27841 attcgaataa ggagggatca gtgtatggaa taccacgaac taaatccctt gattcgcgga
    27901 agagagcttg aacttttgtc caatgagaca tttgaacgga tgattcaaac aaattctgtc
    27961 gaagcacttg gtgaaatatt gaaatccacg atttacagtc catatattta tgacggatat
    28021 gaatatgact tcgaacagaa tcttttaaag gagcagagcc gtctatttcg ctggttaaag
    28081 gaatcagcac cggagcctga aatcgtttgg atctatacga tgcgttatac tttccataat
    28141 ctgaaggttt tgacaaaagc tgagatgaca aatcaaaatc tggaccattt gtatatcgac
    28201 gatggatttt attcattaga aaccttgaag gatgccattc atacgcaagt ttcaaatgaa
    28261 cttcctgaaa gcattatgga cagtatacga gaagtacgtg attattttga agagtctacc
    28321 attcttcagg gaattgacgt gatttatgat cgacagtttt tgacagagca gcgacggctt
    28381 gccgataagc taggatatca agaattgctg acagaagtca ttgcttttat tgacttgacc
    28441 aatatcacaa cgatggctcg aggaatattg cagaaaagaa catatgggtt catgacgacg
    28501 gtactttcca gctcgggaag tatcgaaaaa gaagtatttt tgaactttgt agataaagat
    28561 atggaagatt acacgaattt tctattagag acagattatg ctgattttct gcgccctgtc
    28621 atccgtgagg gaaatattga tctcgtaaag cttgaacagt tgaaagatga ttatctaagt
    28681 tcattgtatc aagaagcaca aacccaggct ttcggaccac tgccactact agcctttttg
    28741 aacgcaaaag aggtagaaag caaaaacctt cgtttactgg ttatcggcaa aagaagccat
    28801 ttcgaatcag aaacaatcag aaagcgggtg agacaagtct atgacgcata agatcggtgt
    28861 agttggcgac aaagattctg ttttgccatt caaattgttt ggctttgatg ttcgttatgg
    28921 tacaaccaag caaaccgttc gtcaggcaat tgaagaaatg gcaaagaatg agtatggcgt
    28981 gatttatgtc acagagcaat gtgcagcatt gagcccagaa acgatcgaac gttacaagga
    29041 acaaatgata cctgctatcg tattgattcc caatcatcaa ggatcattag ggatagggct
    29101 ggaagaaatt caaaaaaacg tagaaaaagc agtaggtcaa aatatcttat agtatgaaaa
    29161 ggagatagaa attttgcaaa ttggaaaaat cataaaagtc tccggacctc ttgtaatggc
    29221 tgagaacatg tctgatgcca gtatccaaga catgtgtcta gtgggagatc taggagttat
    29281 cggagaaatt atcgagatgc gtggcgatgt ggcgtctatt caagtatatg aagagacttc
    29341 tggaattggt ccaggcgaac cggttcgctc tactggtgaa gctttatctg ttgaattagg
    29401 accagggatc atttcacaaa tgtttgacgg aatccaacgg ccattagata cctttatgga
    29461 aatcacacaa agtaatttct tagggcgcgg agttcaattg cccgcattgg accatgagaa
    29521 aaaatggtgg ttcgaaccaa cagtagaagc cggagaaacg gtgagtgctg gagatgttat
    29581 cgggatcgta gaagaaacaa aagttataaa acataaaatc atggtgccaa atgggataaa
    29641 aggaacgatc aaaacaatcg aaaaaggttc attcactatt gatgaaacag tatgtgtcat
    29701 tgaaaccgaa aatggtgaca aaaatttgac gatgcttcaa aaatggccag taagacgtag
    29761 tcggccaatc aaagaaaaat taaacccgga tgcacccatg atcactggac agcgagtgat
    29821 tgatacattc ttcccagtga caaaaggagg agcagcagct gtacctggtc cttttggtgc
    29881 agggaaaaca gtcgttcagc atcaaattgc aaaatgggcc gatgtggaca tggttgtcta
    29941 tgtgggatgt ggcgagcgtg gaaatgagat gacggatgtt ttaaatgaat tccctgaatt
    30001 gattgaccct aatacaggag aatcgttgat ggaacgtacg gtattgattg ctaatacatc
    30061 aaacatgcca gtagcagctc gagaagcttc tatctatacg ggaatcacaa ttgcggaata
    30121 tttccgtgac atgggttatg acgttgctat catggcagac tccacttcac gatgggcaga
    30181 agcacttcgt gagatgagcg gacgtttgga agaaatgcct ggtgatgaag gttatccagc
    30241 ttatcttggt tcacggcttg cggaatacta tgaacgatct ggaagagtca ttgcattagg
    30301 atcagaaggt cgcgaaggaa gtataaccgc aatcagtgct gtatccccgt ctggagggga
    30361 tatttcggaa ccagtcacac aaaatacatt gcgggtcgta aaagtattct ggggtcttga
    30421 ttccagttta gcccaaaaaa gacattttcc ttcgatcgat tggatacaaa gctattctct
    30481 ttattcaaca gaagtaggga agtatatgga tcatatcctt caagctgact gggcatccat
    30541 ggtcaccgag ggcatgcgta ttttgcagga agaacagcag ctgaatgaaa tcgtgcgttt
    30601 ggtagggatt gattcccttt cagataatga ccgtctgaca ttagaagtgg caaaatccat
    30661 tcgtgaagat tatttgcagc aaaatgcttt tgatgatgtc gatacattca cttcaagaga
    30721 gaaacaattc aaaatgttga agatgatctt gacctttggt gaagaaggac gccgtgcgtt
    30781 gtcgttaggt gcttatttaa gtgagatcat ggacggtacc gtatcgattc gtgaaaggat
    30841 cggacgaagc aaatatatcc cggaaacaga attagaaaaa ctagatcaaa ttattggtga
    30901 aatcaagcaa acgatgcaaa cgatcgtttc agaaggaggc atgagcaatg attaaagaat
    30961 atcgtacgat cggtgaagtc gtcggtccat tgatggcggt tgaaaaagtt gctggtgtca
    31021 aatatgaaga attaatcgaa gtccgtatgc aaaatggcga gattcgtcgt ggacaagtat
    31081 tggaagtcca agaagataaa gcaatggtcc aaatattcga aggaacaagt ggtatcaatt
    31141 tacgtgactc ttctgtacga tttttaggcc atcctttaga actaggtgta tcggaagaca
    31201 tgatcggtcg agtattcgat ggtttgggac gaccgaaaga taacggacca gagatcctgc
    31261 ctgaaaagca tttggatatt aacggagaag taatcaatcc agtagctcgg gattatccag
    31321 atgagtttat ccaaacaggt atctctgcaa tcgatcattt gaatacatta gttcgtgggc
    31381 aaaaattacc agtattttct ggctctggtc ttcctcataa agaattagct gctcagatcg
    31441 cgcgacaagc aacggtactc gattcatcag atgatttcgc cgtagtcttt gctgctattg
    31501 gaatcacttt tgaagaagct gaatttttca tggaagattt tcgtcaaacg ggcgcaatcg
    31561 accgttctgt catgtttatg aatttagcaa acgaccctgc aatcgaacgt atcgctactc
    31621 ctcgtatggc tttgactgct gcagaatatc ttgcttatga aaagggaatg catgttttgg
    31681 ttatcatgac agacatgacc aactatgcag aggcattgcg agagatttct gcagcacggc
    31741 gagaagttcc aggaagaaga ggatatcctg ggtatcttta cacgaactta gctactttat
    31801 tcgaacgagc aggaagaatc cgcggactaa aaggatcggt tactcaaatt ccgattctaa
    31861 caatgccaga agacgataaa actcatccaa tccctgactt gactggttat attacagaag
    31921 gacagatcat cttgactaga gagctttaca agagtgggat tcagccacca attgatgtac
    31981 tcccgtctct ttcgcggtta aaagataagg gaactggacc cggaaagaca agagaagacc
    32041 atgcagctac gatgaatcag ctttttgcag cctatgcaca aggaaaacag gcaaaagaat
    32101 tagccgtagt tttaggtgaa tctgctttat ctgatgtaga caagatctat gcgaagtttg
    32161 ctgagcggtt tgaaaaagaa tatgtcaatc aaggattcta cacgaaccgt tcgattactg
    32221 aaacacttga tctagggtgg gaactgctat cgatgttgcc aagaaccgaa ttaaaacgaa
    32281 tcaaagacga catgctggac aaatatctgc cagaagggaa gtgagttctg atggcacgat
    32341 tgaatgtgaa tccgacccgc atggaattga ctcgattgaa aaaacagttg acaactgcca
    32401 caagagggca taaattatta aaagataagc aagatgaact gatgcgtcaa ttcatcctgt
    32461 tgattcgaaa gaacaaccag ctgcgtcaag aaatggaaga gtctatgaca gaagcaatgt
    32521 ctgattttgt attggcaaat gcttcgatca cggaaccttt catcgaagaa ttatttgttt
    32581 tgccggcgga aaacgttgat ttgtctatcg tagacaaaaa tatcatgagt gtaaaagtac
    32641 ctgtgatgaa ttttgaatat gatgaacagc tgacagacac acctttggaa tacgggtatt
    32701 tgaattccag tgccgaactg gatcggtcaa tcgatcggtt tactaccctg cttccaaaac
    32761 ttttggaact gacagaaatc gaaaaaactt gtcaactgat ggcgagtgaa atcgaaaaga
    32821 cacgtcggcg agtcaatgca ttagaatata tgacgatccc tcaattagaa gaaacgatct
    32881 attatattcg tatgaagctg gaagaaaacg agcgcgcaga agtaacaagg ttgatcaaag
    32941 taaaaaatat gggtaccact gactaagtgg tatctttttt taaaagagga aaacgatgat
    33001 taaacaaagc aaacaaataa agaaacgttt gccggctgtt cagcttctcg cattaggatt
    33061 ttttctcctg attttagttg gcggcggcct acttacccta ccatttttta gtaatagtgg
    33121 gcatgggaca aattttatcg atgcgctttt cactgcaact tctgctgtct gtgtaacggg
    33181 attgacaaca ttgaatacag cagagcattg gaacagtgct ggtcaatttt tgatcatgct
    33241 tttgattgag atcggcggtc ttggttttat gatggttccg attctatgct ttgcattgat
    33301 aaagaagaaa gtcagtctca gcacacgtat tatattaaaa gaagcgctga atctagaaga
    33361 agtatcaggt gtgatgaagc tcatgcttta catcctaaaa ttggcctttg tgatccaatt
    33421 gattggtacg gttgctttat cttttgtatt tgtgcctgaa tttggctggt tgaaaggtat
    33481 ctggtacagt ttgttccatg caatctctag tttttgtaat gcagggtttg atttgttagg
    33541 agacagttta gccaatcacc agcaaaatgt ttatttgatc atggtggtat ctgctttgat
    33601 catttctggt gggttaggct tcatcgtatg gcgtgattta ctggaatatc atcagaaaaa
    33661 gaagatgacg attcattcaa aaatcgcatt aaccgttaca ggtacccttt tattaggcgg
    33721 attcgttgtg ttctttttca cagagcgcaa tggggcaacg ctagtggaag ggaatatgtt
    33781 tcaacgattg gcaaacacct tttttatgag tgtgacacct agaacggctg gatattattc
    33841 agttgattac ctccatatga gccatgcagg tctgatttta acgatgtttt tgatgtacat
    33901 cggcggaaca tctgggtcga cggccggcgg attgaaaaca actacgttag gtgtgttgct
    33961 gatccagatg cgttcgatgt tgaaaggacg tacgagagcg gaagcatttg gccgtaccat
    34021 ccgacaaggc gcagtgttgc gggcacttac tttatttttt gttacgttga cgttgtgtgt
    34081 agtcgccatc atgattttat cggtgactga aacgatacct aaaacttctg gcatcgaata
    34141 tattgctttt gaggtcttct ctgcgtttgg tacagtaggt cttacgatgg gattgacgcc
    34201 agacttgact gcaataggga aattgatcat tatagcgctt atgtacattg gacgagttgg
    34261 tgtattgact gtggtcttct ctctgatgac aaaagcacaa agaacacaat caaaatacaa
    34321 atatccagaa gaaagtgtca tgattggata atttcatctt ctgacagaaa cctagtgatt
    34381 tagtaaaata agaaaataaa ataatttttc ttgcttcttg gatactttaa gtgcaaaatg
    34441 ttcgtttatt ttttgaggca ctacccgttg ttgaacctcg ggtagtgcct cttttttatt
    34501 gaaaggaatc aataagattt gattccttta tttatcaata ggttataatt catatttttt
    34561 tattttttct tttacgatac ttagtccaga agctaaaatt tcaaggttat tagaggatag
    34621 ggaaattcga acgaatgcat ctggttgcgt acgtgtagta aagcgtctgg aatgataaag
    34681 tcggataccg ttagcaagaa agtcattctc aattatctta gggtcaatct caggatcaac
    34741 tggaagaatt cgatagtaag ggacacgatt cgttggtttt tctactttga aaagagaatc
    34801 aaaaagctga ttggctcttt ttgtaagact taatttagtt tctaagatcc tatttgcttc
    34861 atttgaatgg aggatttgag tgatgacttc cacatctaat ccagaagttt tcacatttat
    34921 attaaaaatt gcttgttcta tcttgctttg gacatgtact ggaactacaa gataagcaac
    34981 tcgcaatcca gaacaaataa attttgtcat tccagctaag tagattgttt ggttaggtaa
    35041 taaattttgg aaaggaggaa tgatcgtatg ttgatagtaa gttgttaaaa atgaatggat
    35101 atcatcttca ataacccata gaccttcttt ttcaatcact tcggctaatt gctctcgtct
    35161 tttgtgagag atttgaaacc ctataggatt attacaagaa ggcataagaa agacaccatg
    35221 aatcttcttt tttctacatt cctgaatcaa tatatcaggt cgcattcctt gctcgtcaaa
    35281 atcaattgga acgatctcta aatgatataa ctgagccaat tcaatgaaat tagcgtatgt
    35341 atatcggtct gttgctattc tatcacctgg agagaaaagt gcagaaagtg tgatagccaa
    35401 tccattttga acaccggaaa caatagatag agattctaag gacggaatga ctccttgagt
    35461 ttttaaccaa tttgctgcag tagtcaattg aaaatttgtg cctttgggat cttggtaatt
    35521 aagcaaacca acaagatttg ggttattact agttgattga ataaacggga caacgaattt
    35581 attacattct tcaaaagaac taaccagacc aaaatcaatg atatgttcgg ttacttcatt
    35641 ggtagagatg gtgatggact caaagacatt gggagaaata aatgtgccac ttccaatatt
    35701 cgtatacagc aaacctttct caattccata tttataagcc ttgccaacgg tagtaaaatt
    35761 taaatctaaa taatcagcta gctctctttg ggagggtaac tgagtgtttt tctgtaattt
    35821 attctttaaa atatcttgtt ctaattgttg aatcaacgat cgataataag gacgcttcaa
    35881 tttttgtttg tctggtcgcc aagttaacgg gtaattgtca taagaattaa taggcatttt
    35941 ctccactcct taaaattgta taccatacaa ttttaccatt gattgtattg attttagaag
    36001 ttaatctttt gtgaggaggg aattgtctat gaaaattatt aattttgagg aagtagtagc
    36061 ttcttttagt tttgaagaag cgattcaagt aatgaaaaaa tgtttttttg attatgaaag
    36121 tggtaaaatc agccaaaatc ctcgattggt ggaaatttta cctgacggaa aaggcaaaaa
    36181 tatgtttgcg atgatgcctg cttatttggg ggagaacaga tattttggca caaaagtcat
    36241 taccgctttt ccggataatc atcagtatca tttaccttct catttaggag agattttctt
    36301 gtttgatgct caaaacggac tacccaaagc attgataaac gcaaatgcag tcacctggat
    36361 tcgaacagct gctgtatctg cgctggcaac agattactta gcaaatccgc atgcagaaac
    36421 acttgcttta attggagctg gtcaacaagc attgtcgcat ttgactgcga tttctaccat
    36481 tcgtcccatc actacagtgt ttgtttacga tattttagaa gaaagacgaa atacttttat
    36541 cgctaaagct aaaaaacagt atcctaaaat aacgtttata aatgcaatat cagtagaaga
    36601 tgcagtacgt ccagcggaaa tcatttgtac gttgacctct agtaaagagg catttcttca
    36661 aaaagagtgg gtaagggaag acgcacatat caatgctgtg ggcacattta ctcctgatac
    36721 aagagagata agtacatcgt tgatggaaac ttctcaaatc tatgtagatg attactcagc
    36781 tgccttaaca gaaagcgggg acctgcttat agccatggca gaaggagatt tagaggaatc
    36841 ttgtattgtt ggtacattag gcgaattagt ttctgagaaa aaaacatttt ataaaggaga
    36901 atcgaggccg acgattttcg acgcagttgg tctagctatt gaagatcttt gttgtgcaga
    36961 atatatttat aacaaattag agaaaggggc tttaaaatga acttagatta ttacgtagtt
    37021 gatgcatttg cagatgaggt gttcaaagga aatccagcag cggtttatgt gctagaagaa
    37081 tggctgccag aaggtacgat gcaaaaaatt gccattgaaa acaatttatc tgaaacagca
    37141 tttacagtga agaaaaacca agaatttgag cttagatggt ttacgccaga tcgagaaatc
    37201 gatctttgtg gtcacgcgac attagcaaca gcatttgttt tatttaacta ttacaaaata
    37261 cctgatgaaa cgattaaatt ttctactcaa agcggtaatc tatttgtgac aagaattaaa
    37321 gattattatt acatggattt tcctagtatt atgccgaaaa aagtgccgat attgtctgaa
    37381 tatgaagaag cgattggggc taagattaaa gaagcctact tagcacgtga tttatttttc
    37441 gtattagaag atgaaaaaac ggtggctaaa ttgcagccag attttacagc tatcaaaaat
    37501 tttgaattag gaataggagt catcgtgaca gcagaaagtg tgcaaaaaga ctttgtttct
    37561 agaaccttct ttccaaaatt aacaatcaat gaagatccag tatgtggatc agcacattct
    37621 aatcttattc cttattgggc agaaagaatg aataaaacaa aattgtcagc ttatcaaatg
    37681 tcatcaaggg gcggggatct agaatgtgaa ttaaaagaag atcgtgtgat aataggagga
    37741 aaagcagttt tgttttctaa aggtacctcg tttatttgat ttctttcaaa tgaattaaaa
    37801 ataaattggt ggagagtggc aaccttatag ctacaatggt tgttaaaaaa agacgcaaac
    37861 tttttcaatt taatgaaaag tttgcgtctc attttaatta ttggtgtttg ttttttattc
    37921 aatcaagagt aaaatgcccc atactaacta tcctcggatg acttcgattt tataaccatc
    37981 agggtcaatg acaaagtagt aagaaggcgc agtgccaggt aatcctttta agtcagtaat
    38041 ctcaagacca gcagctttat gttgctcgtg taatttttct agatcatcag ctgctatagc
    38101 gatatgacca tagccgtctc ctagatcata cgcaccatga tcatagttgt aagtcaactc
    38161 taattcatag tcatccccag gaagtgtcaa ataaacaagt gtaaatttgt tttctggaaa
    38221 atcacggcgg cggctttctt caaaaccaaa tgccttttga taaaattcga ttgatgcttc
    38281 aagatctttc actcgaacac atgtgtgagc cattttcata gattcatctc tccttttcct
    38341 tttactcaat cataacaaaa agaagtaagg aaatagttga tttgtgcttg ttcatgagaa
    38401 atttctcatg taaaatggat agaaaataaa actgttaagg tggaaactat tcatggataa
    38461 accaattttt ggtgaaaaaa agcaatttgc tgattatcaa acccgttatg cagcatatat
    38521 tgtcatagaa agagatcagc agattgcagt aatcgaggct ccaaatggtg ctttttttct
    38581 tcctggcggg gaaattgaag gagaagagac gaaagaagaa gcgattgtcc gtgagctgat
    38641 agaagaaatg ggaattgtgg cagaaatttc ttcttatctg ggagaagctg atgagtattt
    38701 ttactcgaat tatcgtgcaa cttattatta taatccagga tatttctttg ttgctgattc
    38761 ttggaagcgt ataggagaac caactgaaaa gaccaataaa atttggtggg tgagccctca
    38821 agaagcgctt gtgaaattga aacgtggtag ccaccgatgg gcagtcgaga gatggatcga
    38881 aaaaaataaa aactgaaaga aagcgagtag atcagctttc tctcagtttt tttatttatt
    38941 acagtacata ttttttgatt gcttcagcta caccgtgctc gtcgtttgat gaagtgatga
    39001 catttgctgc ttctttgaca agagaaacgg catttcccat tgctactcct agaccagcat
    39061 attcaatcat ggataagtcg ttctcgttat ctccgatagc catgatttca tcttgatcaa
    39121 taccaaggtg ctgtgcgaga ttcgcaactg ccgcaccttt acttgcttct ttatttagta
    39181 cttcgaagta atagggcgca cttttgaccg ttgtgtattt atcacggaaa gtttgcggta
    39241 aacgcgcaat tgctgcatct aaaatttctg gttcgtcgat catcatcatt ttgacgatgt
    39301 tcatgtctgg tgtcatttct tcaggtgttc gatattttag cggcatcttg actaaacttg
    39361 cttcgtggat cgtataagcg ctgatatctc gattaggcgt gtagatcgct ttgtcatcga
    39421 tcgaatggag atgactgccg acacggcgtg ccatcacttc gatctctagg aaatcttcat
    39481 gtgtcagtcc gtgacgggcg atgattttac ctgatttcgt ttgttgtacg agtgccccgt
    39541 tataagtaat aacgtaatca ttatcttgaa aaaggttcaa ctcgtttaac tgttcctgga
    39601 cacctggtaa gggacggcca gtgcataaaa cgatcgaaac accttttgca acagcagcgg
    39661 caatcgcttc ttttacttct tttgttactt ctcttttctc atttaataaa gtaccatcga
    39721 tgtcgatagc gactagtttg atagacataa tttcctccaa tatattttaa tttatttcaa
    39781 tcaatgcgcc attacggata tggctggcaa attcttgata agtttcgtca aataaatcat
    39841 aatgatcacg caaggacgga tcaaccattt cttttggaaa gaaaaatcgc tcatctcctt
    39901 gttcttgtcc cgctaatgca gcaacaagct gactaacctg tgataattct atcaaagttc
    39961 cgtcatttcg caaaatctcg atttgtgtgc gatgtctgcc ttgttctggg cgataaaaat
    40021 cataaggtag atcgtagcta gaattcacag cagtgtaata aacaggatta tatccgacct
    40081 tttctactaa caaagtgagt tcttggacta attttgaatc ccggttgcca gaaaaagtag
    40141 cagatttcag tggtttacga ttcaaaaaac gtttagctaa atcatttaaa ataggatcag
    40201 cagattcaga ccattgagta aagtaagtgc ccaagacccc atcatcaagt ttgaggtatt
    40261 cttctaaagt aaagcttccg tcaagaaatg gcagaagtaa ttgagaatgg agttcaaaac
    40321 tgctggcatc ttcttgatac aactcgtgtg cgcgatgaag cagatgctcc aaaattactt
    40381 ccataccacg ggaaacagga tggaagtaca cttgcacata catttgatat cggctaacga
    40441 tataatcttc cactgcatgc atgccactca tggaaaaagc gatcccgcct tcataaggac
    40501 gaatcacacg taatattcgg gtaagatcaa atgttccata ttctgttcca gtgaaataag
    40561 catcccgaag caaatagtcc attcgatctg catcgatctg actagaaatc atttggacaa
    40621 cttgtgggtt ggggtaagtt ttttggatca cactagctac cttttcagga aaaccttctt
    40681 ctactcggtt aagaatctga tacacttctg tttctggaga agtgatgatc tctacagtga
    40741 tggcttcatg attcgtatgg aagatatgtt caaatgtatg agagtaagga ccatgaccga
    40801 catcatgcaa cagtgccgca cataaagtca ccagccgttc ctgatcatcc cagcctccgt
    40861 tgcctatttt ttcttttgaa aaatttcgag aaaagatatc gcagattcgt cttgaaatct
    40921 cataaacgcc taatgaatga gtaaaacggc tatgttctgc tccgtgaaaa gtgaaagaag
    40981 aagtgcctaa ttgtttaatg cgtcgtagac gttggacttc tttcgaattg atcaaatcta
    41041 agattacttg atgctggaca tggatatagt tatggactgg atcacgaaaa actttttcca
    41101 taggcagcat ttgatattta taaggggttg tcataatgta gctcctttat gttattacgt
    41161 tgttccattc tctggatttg gttgttccat tgctccagct ggatttcttt ttttagccag
    41221 tcggtagaat cctgtaaatc acttgcagaa tacagctttt caaaagcttt tgcaaatgct
    41281 tctttgactt cttttacaaa aaggggttgg tcaagcagtt cttcaagtgt tgccattgta
    41341 gcaggatcca ctgcaggata gccatttgta ccaaagtctt cttttaaagc agattgataa
    41401 aatcgcttca tgacttgccc gcgtttttcc tgattaccgt tgacacttaa gtacatcata
    41461 acagaaatcc catttttgat ccgacgctga gcgataccgg caaatttttt gccatggatg
    41521 cttaaatcat aagttccagg acaataagaa tgggtgattt cgaatgcttg tatcggtgcc
    41581 tttggaaaag cgtatttagt caataggagc atttgctcgt aagcgtcatc tatggttatt
    41641 ttttttgtgt cactttgggg gaaaatcaaa gaaatattca aaattccttc atctgatacg
    41701 atccctaatc cacctgaatt tctgatcact ggagcgtaac ctgcatcttt cagtgtttgg
    41761 atcccgtcac ttagaaaagg agttcgaaca tccttcatac ctaagatgac tgtgcagtca
    41821 tattgccaga aatgtaaaaa gatttgctgg tgttctttag aatattccgt taatatatct
    41881 gttaatgcaa aaggggaaaa gtcgtttttt tgataaatgt gctgatctag tcgaatcgca
    41941 gggttcattc aaccggctcc tttgtataaa ttcatatttt ctacaatatt atactctaaa
    42001 atcaaagagt tgttttggaa aaaaggtttt ctgtaaaaat ggacaagttg gttgacaaaa
    42061 caaaagaaac taggaacaat gtagctatga gaagtaaagg agaatgaata atggaattat
    42121 cacaaggaac accgatttca atcaaattgc gtacaaaagt aaaacagcaa ggggaagtgc
    42181 aagattttta ttttgatttg aaagggcaaa tggtgacaat tggcgatacg ctgtacatac
    42241 gttataaaga gattcaggag gagacgggcg atgagattcc tgtaacgatc aaattagttc
    42301 cagatggtca tgtacagctg atccgtgcag gagaaatgcg gatgcgtttg aaatttggct
    42361 ataaagaacg gttagaaaca tcctatcgaa caccatacgg tatgatccag attgctactt
    42421 ttacgaaaga actgcatgtt agtttgaaag accgtcccac agcagggaag gttcgaatcg
    42481 attatgatct gttcatggga ccggaaaaaa tcggcgaata ttatttgacc ttggatttta
    42541 cagcgtaaat ataaaagaaa agtttgattt tttgtgtctg attttgtatg ataaggagta
    42601 gactgtgaaa ggacgtgtcc tgattggaaa ttagtgtatt tgaaggtgca aacaaaagcg
    42661 aattatcaat gatcgaagta gcacacgcga tcttagaaca acgtggcgat gtcatggatt
    42721 tttctgattt agctaaccag atccaaaact atcttgggaa atcagacagt gaaattcgtg
    42781 attcactcgc acaattttat actgacttga atattgacgg cagctttatc tcattagggg
    42841 ataatcgttg gggcttgcgt tcatggtatg ctatcgattc gatcgatgaa gaagtaaacc
    42901 atggaatgga cgaagaggat gaagatactc cacgtcgccg taaacgcaag aaagtcaacg
    42961 cctttatcaa tgatgatgaa gacgcgatcg attacaatga cgatgaccca gaagatacag
    43021 atctgacaga agaagatgac gatgatctgt ttgatgacga tgatgatgaa gatgaagaaa
    43081 tcgctgctta taattctgac ttgcaagaaa tcggagcaga tgacccgaca gatgatgaag
    43141 aagacttgcc aggaaatatc gaagaagatt taagtatcat agacgaagac gatgatgatg
    43201 aagattatga agaggaagaa ttttctgact ctgaaaaaga ataaacatta ttttcttacg
    43261 agaggttgtg acagagacga tcagcctatc agaataagga ggtgtgacac gatttttgtc
    43321 acaccttctt ttttgtatat aaaaatccca agtaaataca taaaaaataa aaaaattgaa
    43381 acttttagcg caccttgtac gtcatattaa gtgaggcaga aaggagtgga gaatgatttt
    43441 tactggatat aagaaaaaac ggcagatcga aaaataccgt cacctgctga atggactcat
    43501 cgaaactgat tatcaaaaaa tgttccgtat cacgatgaat tacgtacatg ataaagaaga
    43561 ggccttagat gtgatgcaag atagttttca taaagccctg aactattttg aaaaagaaaa
    43621 agagatcgag cattttagtg catggtttta tcggatattg atccgcacgg cattagatag
    43681 ttggcgcaga caaaaaagga cgcctgtgga cttatttgaa attcaagata tcccccaaca
    43741 gttaccttta gaaacttccg ttgcagagct ccatatgatt ttagataaaa tagacagtcc
    43801 ggaaaaagag attctgatcc tctacttttt tgaaggattt cgtttgaaag aaattgcgac
    43861 tatcttggat atgaatgaaa acacagttaa aacgaaaatg taccgctcat tgaatgcttt
    43921 acgtcaaatc ctagaatgaa ggagagaaga gtgccatgta ttcccaaaaa gaaaatttaa
    43981 aaaaactaaa gaaaacttat aaagaacaag caattcccaa agggcttaaa gaggagatcc
    44041 gccagcgttt tattatcgaa gagcaatcat ttataaaagc aaagcggaga aagagacgtc
    44101 tccaagggtt cggagtatct ttggctatcg taatgattac aacaagtagc cttcttttta
    44161 atagtcaagt tcgaagcttt gcagaagatt tacccatctt aggatcagtc attgaattga
    44221 tcttaggcga acgctttact gatcgatctg aaaaaatcga tattcaggta ccgaagatca
    44281 atacacaaaa tgagaaagaa aataaaacaa ttcatggatt aaatcaaaaa tactttcgcg
    44341 aaggacaagc agattttgaa aaagctgaaa aagaatatgg aaattttgaa acggatcatt
    44401 accaagtttt gggagattat cagaaaatcg tagacgataa ccggtttctc gtgattgaaa
    44461 ggcagatcac ccaaacagca gcagatagcc atgttgaaaa aagatacgac acaatcgaca
    44521 agaaaaacag tgtccagctc tcacttccac ttttattcaa agatgacacc tatctatctg
    44581 ttttgacaaa agaagtcaaa cggcagatgg ccgaacaagt caaggaagat ccatctaagt
    44641 actattggac tgagcaagat attcaagaag ggacgataga aaaaccaaca cttgttacgc
    44701 ctacacgaag tttttatttg aacaaagagc atcaattagt tttgactttt tctcaatacg
    44761 aaattgctcc tggttatatg ggtacaccag aatttgtcat tcctaagtcc gtgacaaaaa
    44821 cgattttggc atcggaagat tatttggatc attagacgag aagtagttgc gactagcagt
    44881 ttcaattttc aagtaagtac aagtaaataa taagaagaga aaaagagaaa gaagagatat
    44941 agtgaaaaga aattatttag ttatcagtat tattgcttta tccgtgcttt tgtttttcga
    45001 aattacttcg gtggcctcct tgatcaccga agtaaaagga caaacacact cttcggagca
    45061 ttcgtcacaa tctttcaaac aatcagaaca atcaaccatt aaaagccaat caactgaaac
    45121 agctaacgtc aaagaagcca ttcaagaatc agcggaaaag gtacaaagtc agtcatcaca
    45181 atcaacacaa gacagtacaa aaacgagccg agatccggct gtcaaaagcg tcgcaatcag
    45241 ctttgatgat ggaccaggag cgaccacaac accgcagctt ctgcgaatct taaaagaaaa
    45301 aaacgtgcat gccacttttt tcgtcttagg agaaaatacg gcgcagcatc ctgaaatcgt
    45361 gaagcagaca gctgaagcag ggcacgagat tggcaatcac acatacgatc atcagaatct
    45421 ggccactctt tctgcccagt cgatgacgga ggaagtgacg aaagcagaca ctgagatcaa
    45481 aaaagtcact ggcaaaaccc ccacttttgt tcgtccgccc tatggttctg tcacgaatgt
    45541 aggagcaacg atcatccagc gaccgatcat cgaatggtct gttgattcag aagattggaa
    45601 gacaagaaat cctgatttga ttttgcagaa gatccaagca acagtatacg atggggcaat
    45661 tattttattc catgatatct atcctgaaac gattcgtgcc gttcctcaag tgatcgatta
    45721 tctgaaagag caagggtatc gcatcacgac agttggggat ttattagggc atccaacggc
    45781 tgtcgagaac tattatggca gaaacgatca tcggccagtt cagtaagtga gacaagtatc
    45841 tttaataaat aacacatttt aataagtagt tgaacacata actaccttac ttgcaaaggc
    45901 ttaacaatat ctatacaggt acaacaaaaa actgtccacc aattttcttt ggcggacagt
    45961 tttcacttaa aaataaagaa gcaactattc gtaaattatg ctaaaatagc agtagaacgc
    46021 gtcctgaggg aatcgaaccc ccgtctcaag aaccggaatc ttacgtgata tccactacac
    46081 taaggacgca agcactggga taattgtaac taaacagata aaaaattaca aggggattgg
    46141 acaaaaaaat gaaatttgag caaaattttt cacaaaaaca gcagcagaca cagaaactag
    46201 ccatgacgca acagttgcaa cagtccatcc aagttttaca atataacagt gaggagctgt
    46261 tggcattcgt tgagaatcaa gcaatggaaa atccattggt ggaagttgtt gagccggaat
    46321 ggcagccaga ttacataaaa gcttcttcat cttcttatga aggagaagag acaaattacc
    46381 taaatcagat tcctgataca aaagggtctt tatttgattc attgatcgaa caagtccatt
    46441 tgaattaccg agatactttt ttgaggaaaa tcgttcttta tcttgtagaa tacatcgatt
    46501 tgaacggatt tttgacgatt agtttagaag aagccggaaa agagattgga gctacgccta
    46561 tccaaatgct cgatgcgttg actctgattc agcaattaga accagctgga gtaggtgcac
    46621 gtagtttgca agaatgtctc atgcttcaaa cagaacgaga tgattatgcg ccggaattag
    46681 cttatatcgt gttggaagaa tgttttgagg aactggtgga gcgaaaatgg aaagaaatcg
    46741 cacaacgttt ttctgttgat ctacatgctg ttcagcagat attcgactat ttacaaacgt
    46801 tgagtccaag ccctggccgg attttcgacc gtagcagcga attgtacatt attcctgatg
    46861 tccgggtatt agtggacgac gataaaaatg tacaagttat ctcaaaccga aaaaatcagc
    46921 caaatatacg ctttcaagag agttacttca aacaaatgtc acaacaagca gataaagaaa
    46981 ctgaaaatta tttaaaagaa cggaaacagg aattcgaatg gttgaagaaa acgatcctac
    47041 aacgtgggga tacaattttg cgggttgctc aagtcattgt ttcccggcaa aaagctttct
    47101 ttatcgacaa ggaacgtcca atcaagcctc ttacgttaaa ggaagttgca actgagatag
    47161 atgtgcatga atccacggtc agtcgtgcag tcaacgggaa atatttggaa acagacttcg
    47221 gtgtatttga attaaaaaaa tttttcacta cacgaattcc tacgaatagt acagaacaga
    47281 cagaagacct ttcagcagat acagcgaaga aaaagctgca ggaattagtc gatcaagaag
    47341 acaaaaacaa gccgttgtct gaccagaaat tggttgaatt gctgaaaaaa gatgagatag
    47401 cgatctcaag acgaacagta gcaaaatatc gtgatttatt aggaatcccg agttcatcaa
    47461 aaagaaaacg ttatgataac taatcagtca aaagactaga aaaagtattt cactttttct
    47521 agtcttttta gttgaaaaac gagagcaaaa ctgttagact tacagtcgtg aggttgagat
    47581 ttccctttat tgatgtgaaa ttcgaatagt taatttcttt ttttatcgta tatgggtcgt
    47641 tttaagtcta cattggacgt aaagtgtcca actaaggaga tcgctatgct ggatgaaata
    47701 aaaatgattg aatctgttgc accagatatt atcgaagtgt tgcaagaacg ctataaaatt
    47761 ttacgaaata tctattggat gcagccgatt ggacgtcgaa gtttatcgga aagtatgggg
    47821 atcacagaac gagtattgcg aacagaaaca gatcttttga aaaatctgaa tttgatcgac
    47881 acctcaaaaa gcggtatgac gctgacaact aagggcgaag aagtttatca aagccttgaa
    47941 aacttcatgg atcagctttt aggtacgcat caaaccgaac aacagttggc agaatatttt
    48001 ggtaaccaac gctgtatcgt tgtttcagga aacagcgaag agcagaccaa agtggctgat
    48061 gcattcggcg aagcgctgag cgaagcccta gaccgactac ttccagaagg cgagaatatc
    48121 atcgctgtga tgggaggaac tactatggct gtggtagccg aacaattgtc taatctggaa
    48181 aataagaaac ggcataacct gtttgtccct gcaagaggcg ggattggtga agcgataact
    48241 gtacaggcaa attctgtcag tgcaagaatg gctgctaaag caaacggtaa ccaccgtgca
    48301 ctttatgttc cggaacaatt aagtctggca acttacaatt ctttactcaa tgagccatct
    48361 atccaagaag tcttaaactt gattagtgaa gcgaattgtg ttattcatag tattgggcgt
    48421 gcattacaca tggcagcacg tcgtaagatg actgaaaaag aattagtcat gctgaaacaa
    48481 gcaaatgctg ttgcggaatc ttttggctac tttttcaatg aaaaaggtga agtcgtttat
    48541 aaggtcccta gaatcggcat agaattgcaa gatttggaaa aagtcccgat catcatggca
    48601 atcgcgggcg gaaaatcaaa agctaaagca attcgagctt atatgaaaaa tgcaccaaaa
    48661 caaacgtggc tcatcactga tgaagctgct gcaaatgaga ttttaaaagg ggtaaccctt
    48721 taaaataaat atttttttga ttttcataag gaggaaatct taaatgacag ttaaagtagg
    48781 tattaatggt tttggacgta ttggacgtct agcattccgt cgtatccaag atgtagatgg
    48841 aatcgaagta gtagcaatca acgacttgac agatgctaaa atgttggcac acttgttaaa
    48901 atacgacaca actcaaggac gtttcaacgg aacagttgaa gttcatgaag gttcattcaa
    48961 cgtaaacgga aaagaagtta aagtattagc taaccgcaac ccagaagaat taccatgggg
    49021 cgaactaggc gtagatatcg ttctagaatg tactggtttc ttcacttcta aatcagcagc
    49081 tgaaaaacat ttaacagctg gtgctaaacg cgttgttatc tctgctcctg gcggaaacga
    49141 tgttccaaca atcgtttata acacaaacca cgaaacatta actggtaaag aaacagttat
    49201 ctcaggtgct tcatgtacta ctaactgttt agctcctatg gctaaaacat tgaacgacaa
    49261 atttggtgtt gttgaaggat taatgacaac tatccacgct tacacaggtg accaaatgac
    49321 tctagacgga cctcatccta aaggtgactt ccgccgtgca cgcgctgctg ctgcaaacat
    49381 cgttcctaac tcaacaggtg ctgctaaagc tatcggttta gtaattcctg aattgaacgg
    49441 taaattagac ggagctgctc aacgtgttcc tgtaccaaca ggttcattaa cagaattagt
    49501 aacagttctt gaaaaagaag taactgttga cgaaatcaat gcagcaatga aagaagcttc
    49561 aaacgaatct tacggataca acacagacga aatcgtttct tcagatatcg ttggtatgac
    49621 ttacggttca ttatttgatg ctacacaaac taaagtaatg acagttggcg acaaacaatt
    49681 agttaaaact gttgcttggt acgacaacga aatgtcatac actgcacaat tagtacgtac
    49741 tttagaatac ttcgctaact tataagatag acaaacgtac aagtgtaaat tatagacatg
    49801 tacatttaaa agcggggaag caatcgcgct tcttccgctt tttttgataa taagtttatt
    49861 caggaggaaa taaaatggct aagaaaacag tgaaagatat cgatttaaaa gacaaaaaag
    49921 ttcttgtccg tgttgacttc aacgttcctt tgaaagacgg cgtgatcact gacgacactc
    49981 gtatcaaagc agcattgcca acaatcaact acgttctaga acaaggcgga aaagcaatcc
    50041 ttttctctca ccttggacgt gtaaaaacag aagaagataa agaaggaaaa tctttagctc
    50101 cagttgcaaa acgtctaggc gaattattag gtaaagaagt aacattcgta cctgaaactc
    50161 gcggagaaca attagaagaa gcaatccgca acatgaatga cggcgacgtt gtcgtattcg
    50221 aaaatacacg atttgaagat attgacggta aaaaagaaag caaaaatgat acagaactag
    50281 gtaaatactg ggcttcatta ggcgatgtat ttgttaacga tgctttcggt acagctcacc
    50341 gtgcacatgc ttctaacgta ggtatcgctt caactggtat cccaacagtt gctggattct
    50401 tgatggaaaa agaaatcaag ttcatcggtg aagcagtaga agaaccaaaa cgaccaatga
    50461 ttgcaatcct tggtggcgca aaagtttctg ataaaatcgg cgtaatcgaa aacttgattc
    50521 ctaaagcaga taaaatcttg atcggtggcg gaatgactta cacattctac gaagcaaaag
    50581 gaatcaagat cggtaactct ctagtagaag ctgataaagt ggaactagca aaagaattaa
    50641 tcgaaaaagc aggcgacaaa cttgtcttgc caatcgacaa tgtctgtgca ccagaatttt
    50701 caaatgatgt tgaaacacaa gtaatcgaag gagacattcc tgatggtttg atggctttag
    50761 acatcggccc agcatcagta aaattatttg ctgatacatt acaaggtgca aaaacagttg
    50821 tttggaacgg acctatgggt gtatttgaaa tgagtaactt tgctaaaggt acaatcggtg
    50881 tttgtgaagc aatcgctaac ttagaaggcg caacaacaat catcggtggc ggagactcag
    50941 ccgcagcagc agaacaatta ggatttgctg acaaattcac acacatctca acaggtggcg
    51001 gcgcaagctt ggaattgctt gaaggtaaag aattaccagg actagcagca atcaacgata
    51061 aataaacgac caagtttgct caattctgac gagtaatcga acaaaaggtg aagggagttt
    51121 tcatgactcc ctagccattt ttcaataaat taaggagtgt gttcctcaat gcgtaaacct
    51181 attatcgcag gtaactggaa aatgaacaaa actgcatcag aagcaaaaga atttgctgaa
    51241 gcagtaaaaa acaaaatccc ttcaaatgac aaagttgatt cagtcatcgg atctcctgca
    51301 ttattcttac aagaattaat gacatcagct gaaggtacag aactaaaaat ctcagcacaa
    51361 aactgctact gggaaaactc aggtgcgttc actggtgaaa cttcaccagc agctcttgct
    51421 gatctaggtg ttcattatgt gatcatcgga cattcagaac gtcgtgaata tttccatgaa
    51481 acagacgaag acatcaataa aaaagcgaaa gctatctttg caaatggtat gacaccaatc
    51541 ctatgctgtg gcgaatcttt agaaacctat gaagcaggca aaactgctga atggatcgaa
    51601 ggacaaatta cagctggttt agctgatctt tcagctgaac aggtgtcaaa catggttatt
    51661 gcttatgaac caatctgggc aatcggtact ggtaaatcag ctgacgcaca aatcgctgac
    51721 gaaatttgtg gagttgtacg tcaaacagtt gaaaaacttt atggaaaaga agtatcagaa
    51781 gcagttcgta tccaatacgg cggttctgta aaaccagaaa atattgctga atacatggca
    51841 aaagaaaatg ttgacggtgc tttagtcggt ggcgcaagct tgcaagcaga ttcattcttg
    51901 tcattgttag acgctgtaaa ataattgttg aaaatttgcg aaaaatgcaa gaaatgtttg
    51961 cactaatgag caaaattaac taaaatcgta tatgagggaa atcccttagg aaaaaacaaa
    52021 ctcaaaggag agacaaaaca tgtcaattat tactgatgtt tacgctcgcg agatcttaga
    52081 ctcacgtggt aacccaacaa tcgaagtaga agtatacaca gaaagcggag cttttggccg
    52141 cggaatggtt ccttcaggtg cttcaactgg tgaatacgaa gcagttgaat tacgtgacgg
    52201 agacaaagct cgttatggcg gtaaaggtgt aactaaagct gtcgacaacg taaacaacat
    52261 cattgctgaa gcaatcattg gctacgatgt tcgtgaccaa atggctatcg acaaagctat
    52321 gatcgcttta gacggaactc ctaacaaagg taaattaggt gcgaacgcta ttttaggtgt
    52381 ttctatcgct gttgcacgtg cagctgctga ctacctagaa gtacctttat accactacct
    52441 aggcggattc aacacaaaag tattgccaac accaatgatg aacatcatca acggcggatc
    52501 acatgctgat aactcaatcg acttccaaga attcatgatc atgcctgttg gcgctccaac
    52561 attcaaagaa gctctacgta tgggtgctga agtattccac gcattagctt caatcttgaa
    52621 agctcgcgga ttagcaactt ctgttggtga cgaaggtgga tttgctccaa accttggttc
    52681 aaacgaagaa ggttttgaag taatcatcga agcaatcgaa aaagctggct atgtacctgg
    52741 taaagacgtt gttcttgcta tggatgctgc ttcttcagaa ttctacgaca aagaaaaagg
    52801 tgtttacgta ctagctgatt caggcgaagg cgaaaaaaca actgacgaaa tgatcaaatt
    52861 ctacgaagaa ttagtttcta aatatccaat catctcaatc gaagacggat tagacgaaaa
    52921 cgactgggac ggattcaaga aattaactga cgtattaggc gacaaagttc aattagttgg
    52981 tgacgacttg ttcgtaacaa acactcaaaa attatctgaa ggtatcgaaa aaggaattgc
    53041 taactcaatc cttatcaaag tgaaccaaat cggtacatta acagaaactt tcgaagctat
    53101 cgaaatggct aaagaagctg gctacacagc agttgtatct caccgttctg gtgaaacaga
    53161 agattcaaca atctctgata tcgctgttgc aacaaacgct ggccaaatca aaactggttc
    53221 tctatcacgt actgaccgta ttgctaaata caaccaatta ctacgtatcg aagaccaact
    53281 tggtgaagtt gcagaataca aaggtttgaa atctttctac aacttaaaaa acaaataatt
    53341 cttttctaat gaagatacat gatcgactat tgaaagatag tcgagtatga tcacttagtt
    53401 aagtaatcga actctctact tgctgaaata tcagcaggta gagagttttt ttgcaactag
    53461 cttctgtata tgatgtttac aaagaatggt acaagaaaag atcatccttg aaaaaggaaa
    53521 gctaacaata actagcatca tataagagct tttaaggata gaacagtaga ataggaatct
    53581 atgagcaagt cctctcgtat aaataaaata ggagggaagt agcagcatat ttttcataaa
    53641 gtggctctct ttcttcattt ttactttggt tgctcctatt tgaaaattcg agcacactca
    53701 aatacaataa aaagaaatgg caagggagag gattagatga aaaaagaaga aaaaatcgcg
    53761 attttacaag agatcatccg aattaaatca gtgaatggaa acgaaggtga agtagcagcc
    53821 tatttgaata agcttttggc aaagcatgac ataacaggag agattgtttc ttacagagat
    53881 ggtagagata atttgattgc tcgttaccaa aagggccaat caggaaaagt gttaggccta
    53941 tctgggcata tggatgtcgt ggcggctggt gatgaatcgt cttggaccta tgcacccttt
    54001 gcagcagaaa tccatgggaa ccgtttgtac ggacgtggtg ctacagatat gaagagtggc
    54061 ttggcagcaa tggtgattgc catgatcgaa ctgaaagagt caggaaaacc atttaacgga
    54121 acagtcaaat tattagccac tgtcggagaa gaagtgggtg aactaggtgg ggaacagctc
    54181 acgaaagcag gctatgtaga tgacttagat gccttgatca tcggagagcc aaccaattac
    54241 agtttgatgt atacgcacat gggatcaatc aactatacag tcacctcgca cggaaaagaa
    54301 gcgcatagct ctatgccaga ccaaggttat aatgcaatca atcacctaaa tgaattcatt
    54361 acgaaagcaa atgctgaaat gaatcacctc gctgaaacaa tcgagaatcc tgtcctagga
    54421 aaaacaatcc ataatgttac attgatcagt ggcgggaatc aagtcaacag catcccaagc
    54481 catgcgcagc tccaagggaa cattcgatcg attccagaat acccaaatga taaaatcatt
    54541 gcattgctgc aatcaatcgt caatgaattg aatcaagaga cagactatca tttggaattg
    54601 atgatcgatt acaacaaaat acctgtcaaa gctgatccag attctccttt gattcattgc
    54661 attcagcaac aattcagcca gccattacct ttagttggag cggcagcaac aacggatgca
    54721 gccgaattta cgaaagctaa ccattccttc gactttgtcg tctttgggcc tggtgtcgtt
    54781 actttgcctc atcaagtaga tgagtatgtt gaaatcgata attatttgga tatgatcgaa
    54841 aaatatcaag gaattatttt atcctactta gcgtaagatt tttttaataa atgaaaaaac
    54901 agagccagat tagcatta
//
LOCUS       DAFLWQ010000007        54045 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.007, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000007 DAFLWQ010000000
VERSION     DAFLWQ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54045
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.007"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            109..468
                     /locus_tag="L1V16_000429"
     CDS             109..468
                     /locus_tag="L1V16_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HBN1274794.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            591..2222
                     /locus_tag="L1V16_000430"
     CDS             591..2222
                     /locus_tag="L1V16_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HBN1274795.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(2284..2925)
                     /locus_tag="L1V16_000431"
     CDS             complement(2284..2925)
                     /locus_tag="L1V16_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBN1274796.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    3111..3187
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            3207..3515
                     /gene="rplU"
                     /locus_tag="L1V16_000432"
     CDS             3207..3515
                     /gene="rplU"
                     /locus_tag="L1V16_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBN1274797.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            3542..3886
                     /locus_tag="L1V16_000433"
     CDS             3542..3886
                     /locus_tag="L1V16_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBN1274798.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            3899..4192
                     /gene="rpmA"
                     /locus_tag="L1V16_000434"
     CDS             3899..4192
                     /gene="rpmA"
                     /locus_tag="L1V16_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBN1274799.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            4626..7433
                     /locus_tag="L1V16_000435"
     CDS             4626..7433
                     /locus_tag="L1V16_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1274800.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            7624..8115
                     /locus_tag="L1V16_000436"
     CDS             7624..8115
                     /locus_tag="L1V16_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1274801.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            8218..9207
                     /gene="manX"
                     /locus_tag="L1V16_000437"
     CDS             8218..9207
                     /gene="manX"
                     /locus_tag="L1V16_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBN1274802.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            9240..10043
                     /locus_tag="L1V16_000438"
     CDS             9240..10043
                     /locus_tag="L1V16_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBN1274803.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            10064..10978
                     /locus_tag="L1V16_000439"
     CDS             10064..10978
                     /locus_tag="L1V16_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBN1274804.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            11061..11435
                     /locus_tag="L1V16_000440"
     CDS             11061..11435
                     /locus_tag="L1V16_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HBN1274805.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            11574..11819
                     /locus_tag="L1V16_000441"
     CDS             11574..11819
                     /locus_tag="L1V16_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBN1274806.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            11991..13055
                     /locus_tag="L1V16_000442"
     CDS             11991..13055
                     /locus_tag="L1V16_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBN1274807.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            13301..13726
                     /locus_tag="L1V16_000443"
     CDS             13301..13726
                     /locus_tag="L1V16_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBN1274808.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            13719..14168
                     /gene="nusB"
                     /locus_tag="L1V16_000444"
     CDS             13719..14168
                     /gene="nusB"
                     /locus_tag="L1V16_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBN1274809.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            14265..15119
                     /locus_tag="L1V16_000445"
     CDS             14265..15119
                     /locus_tag="L1V16_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HBN1274810.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            15120..16457
                     /locus_tag="L1V16_000446"
     CDS             15120..16457
                     /locus_tag="L1V16_000446"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBN1274811.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            16462..16686
                     /locus_tag="L1V16_000447"
     CDS             16462..16686
                     /locus_tag="L1V16_000447"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBN1274812.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            16688..17578
                     /locus_tag="L1V16_000448"
     CDS             16688..17578
                     /locus_tag="L1V16_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBN1274813.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            17587..18405
                     /locus_tag="L1V16_000449"
     CDS             17587..18405
                     /locus_tag="L1V16_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBN1274814.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            18512..18961
                     /locus_tag="L1V16_000450"
     CDS             18512..18961
                     /locus_tag="L1V16_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBN1274815.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            18979..20661
                     /gene="recN"
                     /locus_tag="L1V16_000451"
     CDS             18979..20661
                     /gene="recN"
                     /locus_tag="L1V16_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBN1274816.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(20716..20832)
                     /locus_tag="L1V16_000452"
     CDS             complement(20716..20832)
                     /locus_tag="L1V16_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HBN1274817.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(20905..21861)
                     /locus_tag="L1V16_000453"
     CDS             complement(20905..21861)
                     /locus_tag="L1V16_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBN1274818.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            22032..22400
                     /locus_tag="L1V16_000454"
     CDS             22032..22400
                     /locus_tag="L1V16_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HBN1274819.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            22570..23001
                     /gene="mraZ"
                     /locus_tag="L1V16_000455"
     CDS             22570..23001
                     /gene="mraZ"
                     /locus_tag="L1V16_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBN1274820.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            23022..23981
                     /gene="rsmH"
                     /locus_tag="L1V16_000456"
     CDS             23022..23981
                     /gene="rsmH"
                     /locus_tag="L1V16_000456"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBN1274821.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            23986..24387
                     /gene="ftsL"
                     /locus_tag="L1V16_000457"
     CDS             23986..24387
                     /gene="ftsL"
                     /locus_tag="L1V16_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBN1274822.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            24388..26580
                     /locus_tag="L1V16_000458"
     CDS             24388..26580
                     /locus_tag="L1V16_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBN1274823.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            26606..27568
                     /locus_tag="L1V16_000459"
     CDS             26606..27568
                     /locus_tag="L1V16_000459"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBN1274824.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            27582..28943
                     /locus_tag="L1V16_000460"
     CDS             27582..28943
                     /locus_tag="L1V16_000460"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBN1274825.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            28969..30057
                     /gene="murG"
                     /locus_tag="L1V16_000461"
     CDS             28969..30057
                     /gene="murG"
                     /locus_tag="L1V16_000461"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBN1274826.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            30072..31292
                     /locus_tag="L1V16_000462"
     CDS             30072..31292
                     /locus_tag="L1V16_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HBN1274827.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            31448..32773
                     /gene="ftsA"
                     /locus_tag="L1V16_000463"
     CDS             31448..32773
                     /gene="ftsA"
                     /locus_tag="L1V16_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBN1274828.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            32796..34037
                     /gene="ftsZ"
                     /locus_tag="L1V16_000464"
     CDS             32796..34037
                     /gene="ftsZ"
                     /locus_tag="L1V16_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBN1274829.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            34054..34731
                     /locus_tag="L1V16_000465"
     CDS             34054..34731
                     /locus_tag="L1V16_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBN1274830.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            34745..35344
                     /locus_tag="L1V16_000466"
     CDS             34745..35344
                     /locus_tag="L1V16_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBN1274831.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            35359..35646
                     /locus_tag="L1V16_000467"
     CDS             35359..35646
                     /locus_tag="L1V16_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBN1274832.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            35695..36477
                     /locus_tag="L1V16_000468"
     CDS             35695..36477
                     /locus_tag="L1V16_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBN1274833.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            36498..37205
                     /locus_tag="L1V16_000469"
     CDS             36498..37205
                     /locus_tag="L1V16_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBN1274834.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            37467..40265
                     /gene="ileS"
                     /locus_tag="L1V16_000470"
     CDS             37467..40265
                     /gene="ileS"
                     /locus_tag="L1V16_000470"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBN1274835.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(40314..41840)
                     /locus_tag="L1V16_000471"
     CDS             complement(40314..41840)
                     /locus_tag="L1V16_000471"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBN1274836.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(41855..42502)
                     /locus_tag="L1V16_000472"
     CDS             complement(41855..42502)
                     /locus_tag="L1V16_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HBN1274837.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(42686..43015)
                     /locus_tag="L1V16_000473"
     CDS             complement(42686..43015)
                     /locus_tag="L1V16_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HBN1274838.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            43192..43920
                     /gene="sfsA"
                     /locus_tag="L1V16_000474"
     CDS             43192..43920
                     /gene="sfsA"
                     /locus_tag="L1V16_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBN1274839.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            43936..44949
                     /locus_tag="L1V16_000475"
     CDS             43936..44949
                     /locus_tag="L1V16_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1274840.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            44949..46226
                     /locus_tag="L1V16_000476"
     CDS             44949..46226
                     /locus_tag="L1V16_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBN1274841.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            46289..48991
                     /locus_tag="L1V16_000477"
     CDS             46289..48991
                     /locus_tag="L1V16_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1274842.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            49143..49460
                     /locus_tag="L1V16_000478"
     CDS             49143..49460
                     /locus_tag="L1V16_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1274843.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            49490..49810
                     /locus_tag="L1V16_000479"
     CDS             49490..49810
                     /locus_tag="L1V16_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBN1274844.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            49918..51378
                     /locus_tag="L1V16_000480"
     CDS             49918..51378
                     /locus_tag="L1V16_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1274845.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            51446..51667
                     /locus_tag="L1V16_000481"
     CDS             51446..51667
                     /locus_tag="L1V16_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274846.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            51698..51880
                     /locus_tag="L1V16_000482"
     CDS             51698..51880
                     /locus_tag="L1V16_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HBN1274847.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            51880..52293
                     /locus_tag="L1V16_000483"
     CDS             51880..52293
                     /locus_tag="L1V16_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBN1274848.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            52416..53597
                     /locus_tag="L1V16_000484"
     CDS             52416..53597
                     /locus_tag="L1V16_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1274849.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(53668..53832)
                     /locus_tag="L1V16_000485"
     CDS             complement(53668..53832)
                     /locus_tag="L1V16_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274850.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
BASE COUNT        17865 a         9145 c        11679 g        15356 t
ORIGIN      
        1 gtgccaatat tgtttgtttt caaaggcaaa taaaataaaa aaacatcctt atcgagtaca
       61 attataagga gcaaaaaaat aaaactcatc agaaaagagg aagaagatat gacgatacta
      121 tctagaattt tagtgactct agttgcaatt gaattttttt atatcatgta tatcgaaacg
      181 gtgagaactg attctgacac gacaagtagg gtttttaaaa tgagtaaaga agagttaagc
      241 agaaaatctg ttcaaacatt gtttaagaac caaggagtgt acaatggact attaggagtg
      301 ggactacttt atggagctta tctttcttcc gcatctaaag aaatcacaag tatgctatta
      361 atatctattt tttttgttgc attatatggc agtttgacta gcgatcgttg gattttactc
      421 aaacaaggtg ggctagctct gttggcattg ctttctattt tcttataaat atagaaaaaa
      481 taagaattta tctaacagga aactttgtga aaaatattac tttatctcat gaaatatgat
      541 attctaatga atggtatttt agaaaatttc atgaaaaagg agttagatag gtgttcaaaa
      601 attatgtttc ctcactaaaa aaagaatttt caggttatga tctttcaaga tttcagaaag
      661 atcttttggc tgggatcaca gtagctgctg tagcattgcc tttagccttg gcttttgggg
      721 tatcaagcgg agctgatgcg gccgcaggtt tgattacggc tatcattgcc ggtatcgtta
      781 ttggcggttt atcaggcggt ttttatcaaa tatcaggtcc gacaggtgcg atggcagcta
      841 tcttgatgtc tattgcggca acaaagggaa tgcaaggtgt attgcttgct acttttttag
      901 cgggtctatt tttacttgca gcaggacttt tccgattagg aacactgact tcttttatcc
      961 cagcacccgt aattacgggg tttacttcag gtattgctat cattattgca ttaggtcaga
     1021 tcgataattt atttggtgtt cactcggaag gtacaaacgt tattgaaaaa ctaagtagtt
     1081 atcaaacgat aggatttccg ataaacacag cctctttgat catgggaggg ctagtcattt
     1141 tagggatgtt tatctatcca aaaaaatggg cgaaacgaat gcctagttcg ctgctggcta
     1201 tcattttggc aacagcagtt atgctattgt tccatttacc agtagcaact gtgggtaaga
     1261 ttccacaaac attgatcagt agtaatcgtt tgaatatggg agattttagc ttttctgcct
     1321 tgcaacaagt ggcagttcca gctattagca ttgctttatt aggaatgatt gaaagcttgc
     1381 tatgtggtgc ttcggctggc cgaatggcaa ataagccctt agatagcaat caagaattaa
     1441 tggcgcaagg aattggaaat ctgttgcttc ctttctttgg cgggattcct gctactgcgg
     1501 ccatcgcccg tacaagcgtg gccatcaaat ctggtgcaca aactagatta gctggtatga
     1561 tacatgcagt tgtcttactg ctctccatgc ttgtttttgc gccagtgatg tcacagattc
     1621 caatgccagc acttgcaggt gttttgattg tgacggcttg gcgtatgaat gaatgggaaa
     1681 cgatcaagga gctatttact aataaatatt ggtcagcagt tctattgttt atccttacga
     1741 tgatttgtac agttatcttt gatttaagta ttgctatcgt gatcggggtg atcggcggct
     1801 gtgtattttt tgttgtcaaa agcgctgcta tcacgatttc attagaaacg atcgattggc
     1861 aaagaatggg gctgccagaa acggaaaagc tgaataactg gacagtagtg tatattagtg
     1921 gtccactgtt ttttatgtct tcagaaaaac tcaaaaataa attggaagaa ctaaatcatc
     1981 acgatggtgt cattttctcc atgcgaggcg taccaagtat tgatttgacg gcacgtgcag
     2041 tttttgatga atttcaagaa aaagcagagc aaagaggaca aacgattatc tatacttcct
     2101 tgcagccaga agtagaaaaa caactttctc acttgtggga acatacattc acgcatcaac
     2161 atcaaacagt tgctcatgcg ttgacagctt tacatgcgaa atatactgca attagccatt
     2221 aaaacaatga aaaagaacag acaagactgt aaactgaaga ttttatggtc ttgtctgttc
     2281 tttttaatat tgctgtaaaa gtgaagctag tacttgccag tcttgatgga taacaggtac
     2341 aagggagcga ttgtagaaaa tagctgctgg atgaaaaagt ggaagaattc gatagttttt
     2401 ttctgaccat tcgtaggcat ccttttgttc tgttaattgt aagacaggcc ctgtatagag
     2461 ttgaccatga tttttggtaa ccgtatattc tttgccaagt aaacgttgaa gaccaatgtt
     2521 tccaagtgtc gcaattaatt ttggctggac cttcatcagt tcgtaatcca atattggtgc
     2581 atgcgcaaat acttcggaac gagtaggtgt ccgatttgga taaacagttt ctgactgttg
     2641 tgtccgttta ttgatccgat gagtcacgcg atacgggcgg ctccttacag cactggtgat
     2701 atacacctct tctcgtgtta agccagttga agaaagtgcc tgcatcaatt cttttccagc
     2761 ttgaccgcta aaaggaacat gcgtatcaat ctctgttttc cctggggctt ctcccacgag
     2821 catcagttta ggatgaagag gtccttgccc agcgataaat ccttctacag gacggccgtt
     2881 cattcttaaa gaagcttctt gtatcagttc ttttgggtat tccatttatg ctcctccttt
     2941 ttcttttatt ataagaataa aagaaacaca atgcgactat tttatttggt agaactgtga
     3001 ggatagaaaa gcagaagtat tgcttgaatt tttgttttac tttttgattt taaatttagt
     3061 tgactaacgg ttgctgttct ggtaagctag tactgttgta attgtggact ccacagctac
     3121 aaccgctcag aacaagtaat aagcacagca tatgctgtca cttcggatgg cgagtctaag
     3181 tatatcagaa ggaggtgctt tatagcatgt acgcaattat taaaactggt ggtaaacaag
     3241 taaaagttga agtgggacaa gcaatctatg ttgaaaaact tgacgttgaa gcaggagaaa
     3301 aagttgtttt tgacgaagtt atcttagtag gcggagaatc tacaaaagta ggcgctccaa
     3361 ctgttgcagg tgcaactgtt gaaggtactg ttgaaaaaca cggcaaacaa aagaaagtcg
     3421 ttactttcaa atacaaacct aaaaaacatt cacaccgtaa acaaggtcat cgtcaaccat
     3481 atacaaaagt ggttatcgac gcgatcaacg cttaatagcg tttgagaaag aaggcctata
     3541 tatgatcaaa ggaacattta agcgaaatga cgcaggtcag atcgtttcat tcactttgac
     3601 cgggcatgct gatgctggtc cttatggaag tgatatcgtt tgtgcgggtg tttctgcgtt
     3661 agcgatcagc actgtcaacg ggattgcctc attagccggt tttgagccga ttgttgaaat
     3721 gaatgaagaa gaaggcggtt atctttatac cgaagtcact tcaggaatga cacaagaaca
     3781 aaacaatatt gctgagattc tattagaaaa tcttttatta ggattacaat cgatagaagc
     3841 tgaaaactca gaatatatcc aaattaaaac aattaatgat aaataggagg tgcagaccat
     3901 gttgttatct atgaatctac aattatttgc ccacaaaaaa ggtggcggtt ctacatctaa
     3961 cggccgtgac tcagaatcaa aacgtctagg tgctaaacgt gctgatggac aaacagttac
     4021 aggtggatca attctttacc gtcaacgcgg tacaaaaatc tatccaggtg taaacgtggg
     4081 tatcggtgga gacgacactt tatttgcaaa agttgatggc gtagtacgtt tcgaacgtaa
     4141 aggccgtaac aaaaaacaag tgtctgttta tccagtagct caagaagctt aattgaatct
     4201 tatgattaaa gaggttgtga caagactttt gtcacagcct tttttgttta taaaaataaa
     4261 agttgtagtg gaggctacga agtttacttt gtctttttac acttaatatt tttttgccaa
     4321 tttggaatca ggatgttttg ataactatcg ttttcaattg atggaagcta tattgtttgc
     4381 tatcagtgaa ataattatat ggtaaacagt gttctttttc ttgtttccat tataaaaatc
     4441 gtatcgggat ttttcgttct tttaaattga acatttctat ctatccgcgt gttatcaaca
     4501 aaacaaaatc aggtaaatag ttgacgaaac agaaataaat acatagtatt atgttttgaa
     4561 gcctaagtac aatagtctat agaaaaggag cgataccatt ggcaaaacgc attgaccgaa
     4621 tttatatgta tgtcaaagaa aaaaccgctc atttaacaaa ggcagaatat gatcaaggag
     4681 taacaacaca ggaaattgct gaagtgttag ggattcagcg aacaaatagc agtaaagatc
     4741 tgaatcagct agtgcgcgaa ggaaaactga taaagacaga cggacgacca gtacgttaca
     4801 tatatcaaac actcgttacg cacgtaaagc cagttacaaa acatgtagtc agttacaaag
     4861 aaacgccggt ctctgaagaa aaaaatacac tccaaataga tactaaggat atctttgcaa
     4921 aaatcattgg agctaacggc agcatgaaaa attcagtgga acaggcaaaa gctgcgattt
     4981 tgtatccgcc aagaggatta aattgtttga ttacaggacc taccggatca ggaaagactt
     5041 attttgcaca cgcgatgtat cattttgcaa aagcgcatca tgtaatagat gaggaaacgg
     5101 aactgattgt tttcaattgt gctgattatg ccaataaccc tgagcttttg atgagtcatt
     5161 tatttgggta cgcaaaaggt gcttttacag gcgcagatga agaaaaaatg gggattatcg
     5221 atcaagcgga tggcggtatg ctgtttttgg atgagattca ccggttgccg cctgaaggtc
     5281 aagaaatgat cttttacttt atggatcatg gaacttacag tcgtcttggg gaaacaacga
     5341 aatcccatga agcaaatgta cggatcgtag gtgcgaccac agaagaccca ggttcttctc
     5401 tattagaaac ttttgttcgg cgtatcccaa tcaatatcaa acttccggct tttgaaaaac
     5461 gtcctgcaaa tgagaaagtc gatttagtaa aaatcatgat tgcccacgaa gcaaaccgca
     5521 cgcagcgaaa gatttctttg acagaagatg tagcaaaagc attgatcggc agtgtgacct
     5581 atggaaatat aggacaattg aagtcaaata tccagttagt atgtgcacga ggatttctaa
     5641 atcatatgca atcacccgaa atctcgatca caatcgatga tttgacagaa gggattcgta
     5701 gcggattgat tcaattagca agcaaccgca gtgcaatggc agagctttct aaaatattgg
     5761 agccaaagat aactgtagca ccaaatgata cgatcatgaa aatccaatcg gactcctatg
     5821 agttacctta taatctatat gatatcatcg gagataaagc agctttactg aagtcggatg
     5881 gtttggatca agaagcaatc aatcatttca tttctacaga tatcaacatc catctgaagt
     5941 ctttctataa agaccatggt ttttctttta atgcagacag caaattagca gaatttgtag
     6001 atccgaaaat catagaagtg accaatcaga tttatgtaat ggtcaaaaga tctttaccat
     6061 atgagtttca gcaaaacttt atttatgcta tgagcttgca tatcagttct tttttgaaaa
     6121 aaatcaactt aggagaagaa cggcatacga atgataacat ccgtgagatg gcttttgatt
     6181 ttccagatga atatgctgtt gcgaaagaag tgcgtagtta tatcgaaacg tattttcaag
     6241 tggagattcc agaaagtgaa gactattact tgaccgttct actcgtctcg ttacgggcaa
     6301 atcaagcaag cggcagaatc ggtgtagtcg ttgcagctca cggaaacagc acagcaagca
     6361 gtatggtcca agttgtccaa cagttgttag atgcagagaa cgtacgagca gtagacatgc
     6421 ctttggatat ggatccgaaa acagcattgg accgaattga acgcaatgta caagaagtag
     6481 atgaaggaag cggggtcata ctcttagtag atatggggtc ccttgcgtcg tttaattcgc
     6541 aaattcaaag agacactgga attccagtac gtactgttga tatggtaaca acttctctag
     6601 ttttggaaac tgtacgaaag gtctcagtat tagggacaga tctagatatg ttgcatgaat
     6661 cattgaaaaa ttttcgaggt tacgcagaaa tatcttctgt agaatctgtt caggaagcaa
     6721 aacctattca taagaaaaaa gctgttttgg ctatctgcgc atctggcgaa ggtacagcac
     6781 aaagaatcaa agaattgatc gaacgagcgg taaacaagcg tcaagaaaca gaattagaag
     6841 ttctagcttt gtcgattgtg gaagtgaaag aagaactgcc agttatccaa aaagaatatc
     6901 agatcatagc tactactggg attactgatt tgaatatcca agccccattt attcctttag
     6961 aacgttttat tgatcaaaat atcgaagtca ttttggatca gttgctgatg gaatcagaat
     7021 tggaggaaac tgaattcatc tccctagatg aagagtcagc taaaaatacg tgtgttgagt
     7081 ttatctctga taacttcatc tttattaatg gtagtaagtt aatcgatcca atgtggcaat
     7141 tttctacaca aatctctcag acgacgggaa tcggcgatga agaatatgga ttcaaaatca
     7201 acctagtgat gcacacagca ggaatgatcg aacgtattat tcggaatgaa ccattgactg
     7261 tggaagaaaa cgaattgaca aatacaacga atgatcctct ttatagccaa ttggcagcct
     7321 cagttgttct gttggaagat cagataaaag taaaagtgcc gatagaagaa atgtattatc
     7381 tgctacgtct agtccataat cagttagata aaaaagaata cactgtgcca tgaatacaca
     7441 aaaacgatac acttttatag tgtatcgttt ttgtgtattg gttaagaatc ctttaaattc
     7501 aattagtgta tcgtaaaaaa gttggcacgc tttttgctta tagtagtgtg tgctaggagg
     7561 tggttgttca cacagaaatg ataggggttt ctgtgaagta gtgaggaaga aggagttttg
     7621 cagatggata ttcgattggc acgtatagat gatcgtttaa tccacgggca agtcgcaaca
     7681 gtttggtcga agcaaacagg tgttgaacgt atcattgtga tcagcgatgt agtcgctcaa
     7741 gataaattga gaaagtttct actaaaagaa gctgcaccgc cggggatcac agcaaatgta
     7801 ataaccgtgc agaaaatgat tcaaatctat catagtggat tattatcacg agcaaaagtg
     7861 atgcttttat tcaccaatcc ccaagatgtt gaagcggttg tccgctgcgg tgtacagttg
     7921 aagtcgttga atatcggcgg tatgagtttt actgaaggca aatcaatgat taccaatttt
     7981 gtttcagtaa atcaacaaga tattgattcc tttcgttact tgaacagtca agaagtggag
     8041 ttagagattc gaaaagtacc tgctgacagg aaaatccttt tgatggaact actagcgaaa
     8101 atcaaaaagg tgtagcaaga atggttgttg gaaaaggtca aataattctg ttgtaatggt
     8161 tagcaattat taatattttt gaatttgtta caacaaaagt aaataggagg tataaatatg
     8221 gtagggatta tcctagcaag tcatggacaa tttgctgaag gaatcttaca atccggttca
     8281 atgatctttg gcgaacaaga aaacgtcaaa gccgtgattt tgaaaccaag tgaaggtcca
     8341 gatgacttga gagccaaatt ggaagaagcg gttgcttctt ttgataatca agacgaagtg
     8401 ttattcttag ttgatttatg gggcggaaca ccgttcaatc aatcaaacac attattcgaa
     8461 gagcacaaag ataaatgggc aatcgtcagc ggtttgaatt taccaatgtt gattgaagcc
     8521 tacgcatcac gcttttcaat ggaatctgct catgaaattg cagcacacat cattgaaaca
     8581 gcaaaagacg gtgtaaaagt aaaaccggaa gaattagaac cggcagaagc accgaaagca
     8641 gcagttgaag acgcacaacc taaaggagca cttccagaag gaactgtggt cggagacgga
     8701 aaaatcaaat atgtattagc acgtgttgac tcacgtctgt tacatggaca agttgcgaca
     8761 gcttggacaa aagcagtgca accaaaccgt attatcgttg tttcagatgc agtatcaaag
     8821 gatgatctgc gtaagagact aatcgaacaa gctgctcctc caggtgtaaa agcaaatgtt
     8881 attcctatta gcaaaatgat cgaagtagca aaagaccctc gttttggaaa taccaaagca
     8941 ttgcttttat ttgaaaatcc tgaagacgta ttgacagctg ttgaaggtgg cgtagacatc
     9001 aaagaattaa atgttgggtc aatggcgcat tcggtcggta aagtcgttgt aagtaaagta
     9061 ttgtctatgg gacaagaaga cgttgaagcg tttgagaagc ttgaacaaaa aggtgtgaaa
     9121 ttcgatgtac gtaaagtacc taatgattca cgcgataaca tggatgatat tttgaaaaaa
     9181 gcaaaagctg aattagcaaa agcgtaataa ataatattaa aatttatagg aggcttatca
     9241 tgtctattat ttcaataatt ttagtcgtat tagttgcctt tctagctggt atggaaggta
     9301 ttcttgatga atttcaattt catcaaccac tagtggcatg tacattgatc ggtttagtta
     9361 ccggtaacct cgaagctggt atcgtacttg gcggtacgct tcagatgatc gctttaggtt
     9421 gggcaaatat cggtgccgct gtagcaccag atgctgcatt agcatcagta gcatcagcaa
     9481 ttattttagt tttaggtgga caaggtgtta aaggtgttcc ttctgcgatc gcgattgccg
     9541 ttcctttggc tgttgcaggg ttgttcttaa caatgatcgt acgtacaatc gctgttccaa
     9601 tcgttcattt gatggatgcg gctgctgaag aaggaaacat ccgtaaggtt gaaatgtggc
     9661 acatcattgc tgtatgttta caaggggttc gtatcgcggt cccagcagca gcgttgctat
     9721 ttatcccagc acaaactgtg caatcattcc ttgaatcaat gccagcatgg ttaacagatg
     9781 gtatggctat cggtggggga atggtcgtag ctgtaggtta cgctttggta atcaacatga
     9841 tggctacaaa agaagtatgg ccattcttcg ttattggttt cgttgtagct gcaatttctc
     9901 aattaacatt gattgctcta ggtgctttag gtgttgcatt agctcttatt tacttgaacc
     9961 tttctaaaat gggtggttca tcaaataatg gaggcggaag caactctggt gaccctttag
    10021 gcgacatttt gaatgactat taatcttgaa ggaggaaaat aaaatggcag aagaaaaaat
    10081 caaattatca aaaaaagatc gtttagctgt tgcgtggcgc tctaccttca ttcaaggttc
    10141 atggaactac gaacgtatgc aaaacggtgg ctgggcattt tctatgattc cagcaatcaa
    10201 aaaattatac aaaacaaaag aagaacgttc tgcagcatta aaacgtcact tggaattctt
    10261 taatacacac ccatacattg cttctccaat tttaggggtt acattggctc tggaagaaga
    10321 acgtgcgaat ggcgcgcctg ttgatgatgt agcgattcaa ggggttaaag taggtatgat
    10381 gggtccttta gctggtgttg gtgacccagt gttctggttt acagtacgtc caatgctagg
    10441 tgcactaggt gcttcattag ctatgggagg aaatatcctt ggaccaatca tcttcttctt
    10501 aggttggaac attattcgtt gggcattcat gtggtataca caagaatttg gctacaaagc
    10561 tggttctaaa attactgatg acctttctgg cggattgtta caagacgtaa caaaaggtgc
    10621 ttcaatttta gggatgttcg tattagctgc ccttgtacaa agatgggtat caatcaaatt
    10681 cttaccagtt gtatcaactg taaaattaga taaaggtgct tacatcgaat gggataaatt
    10741 gccttcaggt ggtgaaggaa tcaagagtgc atttgaacaa gttaataatg gcttagccct
    10801 ttctcctgaa aaggtaacaa cattacaaga caacttagac caattgattc ctggtttagc
    10861 tgcattagga ttaacattgt tatgtatgtg gttgcttaag aaaaaggttt ctccaatcgt
    10921 tatcatcctt ggtttattcg tagtcggtgt tgttggacac gtcatcggac ttttataatc
    10981 cataaaaata tagctcgggc gttgtcccga gcttttttta tatagtatac tgttcataaa
    11041 caaatatctg gagggagaaa atggttcaat caatcaatac aaaagtagac ttggtaattg
    11101 atgctacttc gtttacgggt ctgacagatt acgggcaaat catgataggt aataatggtt
    11161 ttgagtttta ccatgcgcga gatagacgca aatatatcca aattccatgg gaagaagtgg
    11221 attatgtact agcatcagtc atgctaaagg gaaaatggat tcctcgatat gccattcaaa
    11281 cgaaaaaaaa tggtacatac acattttctt ccaaagaacc taaaaaagtg cttcgtgcga
    11341 tcagagaata tgtagatgaa gatagaatgg tacaatcatt gagtttcttt gatgtagtga
    11401 aacgtggtat tcgtagtatg tttaaacgca agtaaaaaat aaagaaaact tctaagagga
    11461 ggttttcttt atttttttac tttgcagaag aaaatatgaa atagcaaaac caattatttg
    11521 tcccctttaa atcccatatg ctaaaattga ttagcaaaga aggaggttat attatgagtt
    11581 ggttatggac attgattgtt ggagccgtga tcggagcaat tgcaggtgcg atcaccagta
    11641 aaggaaattc gatgggctgt gtaacgaata tcattgctgg actagtcggt tcaagtattg
    11701 gacaagcgat tttcggcgaa tggggaccaa aagctgcagg tatggcactt attccatcta
    11761 ttttaggcgc agtgattttg gtagcagttg tctcattttt ctttggaaaa cgatcataag
    11821 tttttacaaa atagtaaact aaaaggagtt gcagcgagac tgtgactcct ttttggcttt
    11881 atttatttaa aataaaaaga agttttccgg aaatttttat ttaactgtcg tgtacgaaga
    11941 aaagtttgct ataatggaaa aaagcgtgca aagaaagagg gagtttcatt atgatgctac
    12001 gtgtagaaaa attgcgcaaa aaaatgcaag aagaaaattt ggattcattt ttggttacca
    12061 gtccgtacaa tcttcgttac ttaacgaact ttacaggtac gacaggatta gctgttatta
    12121 ctttggaaaa agcatttttt attactgatt ttcgttatac cgagcaggcg gcagcgcagg
    12181 ctcaagggtt tgaaattatt aaaaatgtcg gacctatttt tgatgaggta gcaaacttag
    12241 tacgcaaaga agaactgcac tcattagctt ttgaggaaac aacagtctca tttttagaat
    12301 attcggtttt agaagaaatc atcgatgcgg aattagtacc tgtttcacag atgatcgaag
    12361 aactcagaga agtgaaagat gaagaagaaa tcgctattat cgaaaaagca tgtcatattg
    12421 cggatatggc atatgatcac atcctgaaaa tgatccaacc gggcatgact gagattgaag
    12481 tcgcaaatca actagacttt tatatgcgtt ctcttggcgc ttcaggtgtt tcttttgata
    12541 cgatcgttgc tagcggattg cgttcggcta tgccgcatgg tgtagcaagc aaaaaaatca
    12601 tcgaacaagg tgacttgatc acattggact ttggttgcta ttacgaaggg tacgtttccg
    12661 atatgacacg tacattcgct attggtgatc ctggggaaaa attaaaagaa atttatcaaa
    12721 tagtcttaga tgctcaatta gcagttattg atgctgcaaa accaggaatg actggtgtcc
    12781 aattagatgc agttgctaga gattatattt caaaacatgg ttacggggaa gcatttggac
    12841 attctacagg acatgggatc ggtttagaga tccacgaagg accaaacgtt tcttctcgtg
    12901 cagaaaagca atttgtacca ggaaatgtga tcactgatga accagggatc tacttaccag
    12961 gaatcggtgg agtacgtatt gaggatgact tgttgatcac agaagatgga aatcgtgtgt
    13021 tgactcgttc accaaaagaa ttgatcatct tatagtttca tcaatagaag aagtaagcgt
    13081 aaaaatcagt gttcacagac tttgttatag aaaatcactc gatttaatga tacactatag
    13141 aagaactttt aagctgtaag agataataaa gttgggtgtt ttctccaatt catagcagtt
    13201 tgcagctgat cggcggcagt tttcttacca cgtgatcact atgccgcatc atagagaatt
    13261 cggatgtatc tcgtgcttag gcaaagggag gaataaataa atggcagatg aaaaaaattt
    13321 gattttaaac gcaaaccaag atttaggaga gatcgtgatc gctcctgaag tcatcgaagt
    13381 aattatcggg attgcagctt ctaaagtaga aggcgtatac ggaatgcgcg gaacttttgc
    13441 cagcaatgtc actgaattat taggacgtgc agctcacgga aaaggtgttt acttagcaaa
    13501 cgaggaagat ggcttgaaag tagatcttta ctgttatcta gaatatggtg tttcagttcc
    13561 taaagtagca atggaaatgc aggaacgggt cagccagcaa gtccttttca tgacggatat
    13621 cgatttatct gaagtcaata tccatgtagt agctgttgtt cctgaaaaat tagaacaacc
    13681 aacaatcgaa gaactttttg aagacgaaga ggaagagaat gaataaagaa ttatcaagac
    13741 acgagattcg ggaaatggca ttgcaggctt tatttccatt agacttcaat gcagacctaa
    13801 caaaagaaga tgcgattttc aacgcaatcg aattagacca ccgcgacatg atcaacgaag
    13861 atgaatcaga gtttgttcct gtttatcttg atacgctagt tggcggtgtc tgtgcaaaaa
    13921 aagatgaatt ggataaagtg attgaaaaac atttaaaaaa caattggcac atcaatcgga
    13981 tctcaaaaat ggatttggtg atcttgcgta tcgcgatttt tgaaatgact tatgtgacag
    14041 atgtaccagc ggctgttgct ttaaatgaag caatcgagtt ggcaaaaaca tttagtgatg
    14101 accgttcacg taaattcgtc aacggtgttt tatccaatgt attgaaagaa ttagaagctg
    14161 gggcgtaagt cctagctttt ttctatgaat catcataaac ctgttataaa tcgggaaaat
    14221 tctatggtag aatgaaaaca caaaaaatat ctgggagtgg ttagatggca gaattgatta
    14281 acggaaaaga attagctgaa aaaatgcagg cagagattgc tgaaaaaatc caaaaattga
    14341 aagataatgg tatccatccc ggattagtcg ttttattggt aggggaaaat ccagccagcc
    14401 aaatctatgt aagaaataaa gaacgtgtag caaaagaaat cggaatccat tcattggtag
    14461 agcgttatcc tgagacgatt tctgaagacg aactacttgc agaaattgaa aaatacaatc
    14521 aagatcctag ttttcatggt atattggtcc aattaccatt gccaaagcat atagatgaag
    14581 aaaagatcct gttagctatc cgccctgaaa aagacgtaga cggttttcat ccgatgaatt
    14641 taggcagact ccttgcgggt aaaccggaca agattccttg tactccatac ggcatcatga
    14701 aaatgtttga agcttattct atcgatccgg cgggtaaacg agcagtagtt atcggacgaa
    14761 gcaatatcgt cggtaaaccg atggctcagc tactcttgat ggcagatgca actgttactg
    14821 ttgctcattc taaaaccgaa aatctggctg aactggcaca agaagcagat attttagtcg
    14881 tagcaatagg acgtggacat tttgtcacaa aagaattcgt aaaaccaggt gctgtagtga
    14941 tagatgtagg gatgaatcgt gatgctaacg gtaagctgat cggtgatgtg aaatttgatg
    15001 aagtggagcc tattgcaggc tggatcactc ctgtgccaaa gggtgtaggg ccaatgacta
    15061 tcacgatgct gatgtatcaa accgtaaaat ctgccgaagc ttttggagca ggtgaataga
    15121 tggcacaaga atatttaact gtcactacat taacgaagta tttgaaaaga aaatttgatg
    15181 ccgatcctta tttagaacgc gtatatttaa caggcgaaat atcgaatttc cgtttacgtg
    15241 ccaatgccca tcaatatttc agcttaaaag atgaccatgc aaaaatatct gctattatgt
    15301 tcaaaggagc attccaaaaa ttacgattcc agccaaaaga aggaatgaaa gtccttgtcg
    15361 ttgggcgtat ttcattatat gaagcgggag gttcttatca aatctatgta gagcacatgg
    15421 agcctgatgg aataggtgct ttatatcaag aattggaaga acgaaaagaa aagctgatga
    15481 aggaaggcct ttttcaaggg cctaaaaaaa tgctgccacg tttcccaaag cgaatcgcgg
    15541 tccttaccag tccaagcgga gcggttatcc gcgatatcat cacgacggtg aaaagaagat
    15601 atccaattgt ccaattggtt ttgttcccaa cagttgtaca aggaaaccaa gcagcggaca
    15661 atgttgtcag gaatatccag agagtagaag agatgggcaa tttcgataca atgatcatcg
    15721 gtcgtggggg tggttcgatt gaggatttat ggccgtttaa tgaagagcgg gttgctcggg
    15781 cgatttatca agctaatacg ccggtgattt catctgtagg acatgaaaca gataccacga
    15841 tcgctgattt agtagcagat gttcgggctg ccactccaac agcagctgca gaattagctg
    15901 ttcctgtttt gtcagaagag ttgatgcgca ttcaagaacg gcaagctaga ttgcagcagg
    15961 cgtttgtacg ccagatccag cgcaaacaag aacggttcga gcgtgctcga cgttcctatg
    16021 tatttcggca gcctgaaaga ttgtatgaag gtcagaccat caaattagac cagttgaaac
    16081 agcgattata tcaagctaca cagcaaattt atcatgcgaa agaaaaacaa acgatcgcat
    16141 taagccacca attggaacaa gtggctccgc tttatcgagt taaagcagct cgccaagaaa
    16201 ctgcttatct agaaaaacgc ttagaagaga aaatccaaca atatatgaaa caacagcagc
    16261 agcgttttgc tcaagctgtt caatctcttg atttgttgag tccattgaaa atcatgggaa
    16321 gaggctacag ctatacgacg ttaaatgatc aagtagtaaa aagtgtcacc gagattcatc
    16381 aaggggattt gctgacgatc cattatcaag atggaatcgt taaaggacaa gtacaagaga
    16441 tagacaaagg agaataaaaa tatggaaaat ccaacttttg aagagtcact gcaagaatta
    16501 gaaaaaattg tcatgcagtt agaacaagga gacgttccat tagaatcagc tctagattcg
    16561 tttaaacgag gaatggaatt aagcaaacat tgccaagata cattagctaa agcagaagag
    16621 accttgacga aaatgatgac agaatcaaat gaagaagttg attttgacgg aaacgaggaa
    16681 agctgagatg agattaactg acttttcagc tattcatcta cctgctgtag aaaaagaaat
    16741 cttgtctttt ttagatgagc atacaacgga tagaggactc tatgatgcga tgagttattc
    16801 agtgaaagca ggcgggaaaa gaatacgtcc cttattactt ttaacggccg ttgcttcctt
    16861 tgatgagcct attgatgttc ccgtctatca agtagcagct gctttagaaa tggtgcatac
    16921 gtattccttg atccacgatg atttgcctgc gatggacaat gatgatcttc gtagaggaaa
    16981 acctaccaat cataaagtat tcggcgaagc attagctata ttggccggag atggtttgct
    17041 tacaggagca ttccagctaa tcagtatggc acacttaggt aattctccta agcttctgct
    17101 gcttcagcaa ttagctgttt gtgcgggatc acaaggtatg gttgctgggc aagctgcaga
    17161 tatcgagggc gaatcgaaaa agctttcttt agaagaatta gcatttattc atgaaagaaa
    17221 gacagggcat ttgattcgtt atgccttgct ggctggtggc atattagcga agcaacctga
    17281 agaaatctta ttgctacttc aacgattagc cgaacattta ggtttagctt ttcagataag
    17341 agatgatcta ctcgatgtga ttggtacaac gaaaacatta gggaaaacag ctggtaaaga
    17401 tgaacgtatg gaaaaaaata cttacccgcg tttattaggc ctagaaaaga cacgtgaggc
    17461 gttggagatt gagctgttat ccgccaacaa gatcatagac aaattagaag aggacgtttt
    17521 ttcttttgat ggcgggctga tgcgccagat gatcaagcaa tttgatgtgg agaaatgagg
    17581 gaaagaatgg aaaaagaacg cgtagatgta ttagcggtca aacaaggatt atttgaaaca
    17641 agagaacaag ccaaacgttc agtgatggct ggtttgattt acaacgaaaa aaacgagcgg
    17701 tttgataaac cgggagaaaa aattccagtg agtagtgaat taagagtcaa aggtaaaaaa
    17761 cttccttatg tttctcgagg gggattaaaa ttagaaaaag cactcaaagc atttgatcta
    17821 tctgttgaag gaaaaacatt gttagatatt ggtgcatcca ctggcggatt tactgatgca
    17881 gctttgcaaa atggcgcaaa aatgagttat gctttagacg ttggctacaa tcagctagct
    17941 tggaaaataa gacaagatcc tagagtcgtc gtaatggaaa gagtgaattt tcgttatgca
    18001 aaacccgaag actttacctt aggaattcca gaagttgctg ttatcgatgt ttcttttatt
    18061 tcactaaaac tgatgctgcc tccattacat gctattttaa aagaagaggg agaagtgatt
    18121 gctttaatca aaccccaatt cgaagcaggc agagaagctg tagggaaaaa cggaattgtt
    18181 cgtgaccctc agacccatca aaaagtttta gaagacattt tgtcatttgc ggcacaaggt
    18241 ggatatgatg tgctggaatt aagttattct ccgatcacgg ggggagaagg aaatatcgag
    18301 ttcttggctc acttgaggaa agtacccgaa agcggaacaa tcaattcagc tattaatatg
    18361 gcagaagtgg tttcaaatgc acacgaacag tttgaccata aataaattgt aactgtgaaa
    18421 atcaagtgag aagtatgcgg attcttcttt attataccaa ggaaataagc tatcattgat
    18481 taagaagaat atgctaagga gcgaagacgt aatgagaaaa aaagatcggc atcgtttgat
    18541 tactcgattg ttgagtgagc aagatatccg aaagcaggaa gaatttgttg aaatcctgaa
    18601 aagcaaagga atatctgtta ctcaagctac gatttccaga gatataaagg aactgaaact
    18661 gatcaaggta ccggcttcag atggcggcta ccgttatagc ataccagctg aaacaaacga
    18721 agatgtaaat actaaattgg aaaaactatt aaaagacgct ttcgtggcag ttgaccaaat
    18781 ggaaaaattt gttattttga aaacattgcc gggaaatgct tcggcagcag caaatttgat
    18841 tgataaacgt tacaagaaag aattattttc gattatcaat gatgacgata atgttttgat
    18901 gattacacga actgaagacc aggcagtttt attgaagaaa gacttcctgc attaccttta
    18961 agttgaggag cgaatgtgat gctacaagaa atcagtatta ctaactttgc gattattccg
    19021 gaattgcggc tttcttttca cgaaggaatg accgcgctga ccggagagac tggtgcgggt
    19081 aaatccatta ttatcgatgc tttaggtctg ttagcaggag gaagaggttc aagcgattat
    19141 atacgtcaag gagcagaaaa atgtgtgctt gaagggttgt ttgaactacc aaaacaagaa
    19201 ggattctctg aactgatggt tgaattaggg atcgaaacag atgaggacaa tctgattgtt
    19261 cgacgggata tgtccttaac tggaaaaaat gtttgtcgag tgaatggtca tattatcaca
    19321 ttagctaatc tgagaagaat cggcagttat ttagtagata tccaaggaca aaacgaacat
    19381 caggaactgc tccagcctga atcacatctt gctttattgg atcgttttgg agatgtagct
    19441 ttccaacaga agaaaaagag ttatcagcaa gaatatatct cttatcgtga gctggaaaaa
    19501 agggtacgaa aagtgcagca aaatgaaaaa tcctatgttc agagaataga tatgctccat
    19561 ttccagcaag aagaaatagc tgctgctgat ttgcaagtcg gagaagaaga gaaattaaaa
    19621 gaagaaagag aaaaacttag caattatcaa aaaattgctg atggattagc tgcaggttac
    19681 ggagcactga cgaataatga acaaaacagt gtagatggtg ttggcttggc cgtttcagaa
    19741 ctgcaaggga tcgcccatct agatgtggag tatgaagcaa tttatgaaaa tatccaaagt
    19801 gcttactatt tgctgcaaga tgcaatcggc gatatgagtc gtcagattga tttattggag
    19861 ttagatgaga gtcgtttaga agaagttacg caacgtttag aattaatccg acagttgaaa
    19921 cgtaaatacg gcgaatccat tgagtcaata ttggcttact atgacgaaat caccgaagag
    19981 ctagcttctt ctgatttttc agaaggtcaa ttggacaaaa tgaaagagga actagagcaa
    20041 aaagagcttc tacttcagca acaagccgca gatcttcatg aagcgcgtaa aaaaatcgca
    20101 aaagaattgg aaaaatccat tctgcatgaa ttgaaaagtc tgtatatgga aaacactgag
    20161 tttgaggtac gtttcttaaa agaagaaaat agacaattga atcatgatgg atttgaccaa
    20221 atcgaatttt acattacgac caatccagga gagccactga agcctttggt gaaagtcgct
    20281 tctggtggcg aactgtctcg gatgttgctt gctttgaaaa ctattttttc ttctgagcaa
    20341 ggtgtgacaa gtattatttt tgatgaagtg gatacaggtg tgagcggaag agttgcacag
    20401 gccatcgcag ataaaatttc tcaaatatcg aaatactctc aagttttgtg catcactcat
    20461 ctgcctcaag ttgctgcagt cgccgactat caatattata ttgtgaaagc agtgattgat
    20521 ggacgtacgc aaacttctgt ttcagagttg aaaacaaaag aaagagaaga agaaattgca
    20581 cgtatgctgg ctggaagtga gattacaaaa ctcacactcg aacatgcaaa agaactattg
    20641 aaactcgcaa aaaggacctg agccacctcg cagtggttca ggtccttttc agcagctgat
    20701 agctatattt tatttttaca tgacactcat tacagcagtc aatacaacag atccaatcgt
    20761 taaaatcagc attgtccaaa tgacaaattt tgttacttta gcaaaagtac ttgtttgttt
    20821 tttttcacgc attgttttca acctcgtcat taattagttg attcaagtgt acaatctttt
    20881 ttccatttcc acaagagggc ttttttataa aaacttccct ttttttaaat aataggtagt
    20941 tacgatacaa ataaataatg ttaatagaac tagccatata aaggcatcat ccctttcagc
    21001 aataggtaac ttaatgttca ttccatagat actgccgacg attgtcggta tagttaaaat
    21061 aatcgttaaa gaagttaaaa ttttcataat attattcaga ttattcgata cgattgctga
    21121 aaaagtctga ttcatttgtt ctactagttt taattgaatg cgagaagtag tcattgcctg
    21181 ctctgtttcc accaatacat cacgtaaatg atttttcaaa gcatgatttt cttggaaaag
    21241 tttattttgc gctagttctt tcaatgcatc taaattagca gaagtcgctt ctctgaaata
    21301 aacgaggctt ttttggatat ccatgatttg ataaagttgt ttgttttcag tggatacttg
    21361 aagtttggct tccaaagtat cgcattgaga ttgaagcgta gctaaataac tgttgtaaga
    21421 gagtgtgacc tgccaaatga attgaaagaa gatattgaga ttaggcgaaa tatcactttt
    21481 tggaaaggtc tggctaaaga ctttctttaa aaacagtggt tcatgattcg taattgtgat
    21541 aagcttcttt ttgggcgtca aaataataga gagcgggtat gtatccactt gaaaataacc
    21601 gctaggactt gttttagcaa aaggatattg taacaataat aacgctggct ttgtcaactt
    21661 tgattgattg aattcttctg tacgggaatt ttctgcatcg tccaatatgg aagtgatgta
    21721 atctgacgga atttcaaatt gatgtgtcag ctgatgaatc tcttcttgat taggacgttc
    21781 tacacaatac cagatcgttt ggtcagtttc ctttccggta ttacgcagtt tctcattatc
    21841 taatgtaaaa tatttgatca tgattttcct cctgttgcct gtttctttta ttataacgga
    21901 tagggaattg gaatacatgg aatgtgtttg taagatatag aatataactg cataaattta
    21961 aataaaatga aacagttgtg taaagtatat acagtatact tgaagcaacg ataaaaaagg
    22021 agtttacgtt catgggcaca ttcacaccac ttatcttgtt ttggtatatt tacccggtaa
    22081 tcgttttgtt tggttgccaa tttcttgtaa aattattttc gttaaatcgt cgttttaaaa
    22141 taaaagcccc tgatttggcg attccttttt tgtggggcgg tatgcatgca ttgtctagaa
    22201 atacagggac aatttctatc ttaccgtttt tctttatttc tgttttgcta atgggaattt
    22261 gtattgctgt tttccaagca tattattatg aagaaattat ttatccgcgt tatttcaaga
    22321 tgacttggcg tttggttttt ctgttgacaa tcgtcttgta cgctgtcttg atcattgtga
    22381 acatactttc ttacctatga aaaaaataga aaagctgtaa aaagtctttt aaaaggcttt
    22441 ttgcagcttg atttttaaaa aaatgtttat gaataaaaaa agttgttccc ggatttccca
    22501 gaaaaggtgg tagaaagtgg gggattgtgg tagactaatt ttagttagtg gaggaatggg
    22561 gggctttcaa tgttgatggg tgaattccaa cataatattg atgcaaaagg acgtttaatc
    22621 gtgccctcaa aacttcgtga agaacttggc gaaaagtttg ttctgacacg cggattggat
    22681 ggctgtcttt tcggctatcc gatgagcgaa tgggaaaatc tggaagctaa actgaacgaa
    22741 atgccgttgg ctaaaaaaga cgcacgtact tttgtgcgat tcttctattc ggctgccact
    22801 gaatgcgaac ttgataaaca aggacgaatc aatataccca gcacgttaag aaattatgca
    22861 gctttgacaa aaggttgcgt agtcatcggt gtatctaacc gaattgaaat ttgggatgag
    22921 acacgatggc aagatttttc tgcagcagca gaagagaact ttgacgaaat tgctgaaagt
    22981 atgattgatt tcggactata agaataggaa gaggctgact aatgactgaa acatttcaac
    23041 actatacagt catgttgaaa gaaacggtag atggattgaa catcaaaccg gatggcgttt
    23101 atgtagactg tacactcggc ggtgccggac atagtgaata tttattaagc caactaagtt
    23161 ctaaagggca tctgtatgcg tttgaccaag atcaaaaagc aatcgatcac gccaagctgc
    23221 gtttagcttc ttatgtcgaa caaggtatgg tcacatttat caaagcgaac ttcagagaat
    23281 tagaagaacg cttgagtgag catgtagata aggtagacgg cattttgtat gatctagggg
    23341 tttcctctcc tcagctagat gaagcagaac gtggatttag ttatcatcaa gatgcaccgt
    23401 tggatatgcg catggatcag tcagctcctt tatccgctta tcacgtaatt aatgaatatt
    23461 cctaccatga attagtaaag attttcttcc gctatggcga ggagaaattt tccaaacaaa
    23521 ttgctcgtga aatcgaacga gtacgaaaaa caaaaccaat ccaaacaact ggtgagcttg
    23581 tcgaaatcat taaacaagtc atcccagctc ccgcaagaag aaaaggcggg catcctgcaa
    23641 aaagaatttt tcaagctgtg cggattgcag taaatgacga actcggtgcc gaagaggcct
    23701 ctttagaaca ggcaatccgg ttattgaaag tcaatggaag aatcagcgta atcacattcc
    23761 attcattgga agacagaatt gtcaaaagta tgtttaaaga atatagtacg gtacaagatc
    23821 taccaccggg acttcctgtc atacctgacg aattccaacc agaactgaaa gtcattactc
    23881 gtaaaccaat ccttccttca gaggaagagc taacagaaaa caatcgatca cgcagtgcaa
    23941 agttacgtat tgcagaaaaa ataagaatga aagaggagta gaatgatggc agaattaaag
    24001 aaaatgcaag attacgaata tgatttacct gaattggtgg atcagccgga acaacaaatg
    24061 cctgattctt cttcgaatca agaaatcatt cttccacaat caccggcaaa acgattaaag
    24121 cagatttctg ctttggaaaa aattgctgtg gcaagcgtgg cgattgctat tgttgcttta
    24181 tgtgttttaa cagttatgct gcgcacaaat atcagcggag ctgaaaaaga aatcacgtca
    24241 atacaaacag aaatcaatga taaaaagcaa gaaaaaacga gtttagaaca agaaaaaaac
    24301 gaactttctc gtactgaacg gattaaacaa atcgcagaag aaaaaggatt gtctattaat
    24361 gacgacaatt taaggaaagt gaagtaaatg agtcttaaaa ataaaattcg gcggtttatg
    24421 gaaaagaaaa atctaaatcc gatgaacaat cgcaaaaaag taggtatcat tttatttgct
    24481 acgagtattg gattgttctt tttatttgcc gtccgtttct cgtatatcgt tattggaggt
    24541 catgttgctg gtacctcatt agctgaaaaa acaaaacagt tgtaccaagg aagtgaagta
    24601 gtaaaagcaa aaagaggaac gatttatgat cgtaacggtg tggcgctcgc agaagatgcc
    24661 tcctcttatt caattaaagc gatactctca aaaacatata cctctgggga taaaaaactg
    24721 tatgttgaag aaaagaattt tgataaaata gcagaaatcc tgcataagaa tctttctata
    24781 gacaaaaaag atgcactgaa tattttagag gacggcgcaa aaaaagagct gtatcaagtt
    24841 gaatttggta gctatgggaa aaatatctcc caagaaacca agcaaaacat cgaagcggac
    24901 atgaaaaaag aaggtgtcgc tggtctttat tttgtcgacc atcaggctcg gatgtatcca
    24961 aatggcgtct tttcttctca ttttattgga tacgcagttc cagacaaaga tgagaatggc
    25021 ttagttggta aactaggttt ggagtctgct tacaatgata tcttgagcgg taaagatggt
    25081 aagattattt atcaaaaaga taattttcaa aatcctctgc caggtacagt ggcagaagaa
    25141 gaaaaagctg tcgacggaca agatatctac acgactttag acagcagact acaaagttat
    25201 ttagaaacac tgatggatca agtaaatgaa gaatatcagc cagaagaatt gacagcagtc
    25261 ctgatgaaag caaaaaccgg agaaatcttg gcaatgggac aacgacctac tttcaatcct
    25321 gaaacaatgg aaggattgac tggaaaagat gctatctggc gtaatttctt ggtacaagat
    25381 agttatgaac caggatcaac catgaaagtt ttcactactg cagctgctat cgaagaagga
    25441 gaattcaacg agaatgaaac cttccaatct ggaaaaatcc aagtagaaga tgctacgatc
    25501 aatgaccatg actttggtga aaaaggtgtg ctgaccatgc gtcaagctct ttcatggtca
    25561 agtaacgtcg ggatggtcat actggaacag cgattaggcg gacgatggta taactattta
    25621 caaaaactgg gatttggaca aagtactcat tctggattag atgatgaagt aaacggtgct
    25681 ttacctacat taaatattgt cgaccgagca atgagtgctt atggacaagc ggtaggtgtg
    25741 acgaatttcc aaatgatgaa agctttcact tctattgcga ataacggtac aatgattcaa
    25801 cctcgatata tcagcaaagt ggtggatccc caaactggag aagagcgaac aactcaaaca
    25861 gaagttctag ggcaaccttt ttcaaaagaa acaacagaaa aagtccgtga atatatgaga
    25921 gatgttgtcg aaagcgaaaa ctacggtagt gcttatggtg tatatagtgt acctggatac
    25981 aatgtatcgg caaaaaacgg aacagcccaa atcgcttctg atacaggggg atatcaaaca
    26041 ggagatacag cctacctgta ttcgattgtg gagatggttc cttctgaaga tccagactat
    26101 gtcttgtatc taacaatgaa acaccctaag acatatgatc gaatggcatt ggctaaaatc
    26161 gcaaatccat tgatgaaacg ggcaatggat tttaaagaaa ctgaagaaga ttcagataca
    26221 gaaacaaaaa cagaaaaagt atccgtagcc gattatcgta atcttgaagc ggacgttgca
    26281 gcagctgatg ctcaaaaaag tggactgcaa cctgtagtga tcggtaatgg taaaaaagta
    26341 caaaaacaat ctactgccaa cggtgatcag ttgatctctg gagaaaaact gatcctatat
    26401 actggtggtg ataagctgat gcctgacgta acaggatggt caaaagcaga tatcatgaag
    26461 ctggggaaaa tcctcggtat tgaagttagt tttgatggag atggttattg tgtcaaacaa
    26521 gaacttgctc catatgaaaa aatcactgaa gacaaactta gttttacttt agaagaataa
    26581 gaagagaaat aggagagaaa agagcatgga atggacacaa gcattgattc ccattgtcag
    26641 cagttgtgca atgacaattg ccgcaatgcc gctatttatt ggttattttc aaatgaaaaa
    26701 gcaaggtcag gcgattcgtg aggagggacc aaagtggcac aatagcaaag ccggaactcc
    26761 tacaatgggc ggcttagtgt ttctgatcgg ctctattttg acaggaattt gggttggagc
    26821 ttggcaaaaa cagctaactc ctactctttt catcttgctt tttgtattag cgttatacgg
    26881 agtaatcggc tttcttgatg attttataaa aatattcaag aaaagaaaca tgggactgaa
    26941 ctcgaagcag aaattgattg gacagattct agggggaatc atcttttatc ttgtttaccg
    27001 ttctgaaggt tatccaggtg tattgaattt cttcggacta gatctacctt taggaatcat
    27061 ttatggtatt ttcgctctct tctggcttgt tggattttca aatgcagtaa atctgacaga
    27121 tggcatcgat ggattagttg ctggcttagg aagtatctct tttgcagctt acggtctaat
    27181 tgcttggcat cagcatcagt atgatgtatt aatcatttgc ttaagtgttt taggaggttt
    27241 actgggtttc ttcgtctaca acagaaaacc tgccaagatt tttatgggag atgtcggttc
    27301 attagcgttg ggcggacttt tagcggcaat ttctataatg ctaaaccaag aatggacatt
    27361 gcttttgatt ggtttgatct atgttatgga aacagcaagt gtgatgcttc aagttacttc
    27421 ctttaagctt acaggaaaac gaatttttaa aatgtctcca attcatcatc actttgaaat
    27481 gtgcggatgg tcggagtgga agattgatac agttttttgg ttgatcagca ttgtgacttc
    27541 gttgatcaca ttatggatcg tttggtagga gatgacggga aatgaaaaaa atatcaacat
    27601 atgaaaataa gaaagtgctt gtcttaggac tcgcaaaaag cggagtaagt gcggccaaat
    27661 tattacatga attgggcgca cttgtcaccg ttaatgatgg aaaacctttt gacgaaaatc
    27721 cggaagcaca agagctgctt tctttaggga taaaagtaat aacaggtagt catccaatcg
    27781 aattgttgga tgaagaattt tcattgatgg tcaaaaatcc agggattccc tacagtcatc
    27841 ctttagtagc aaaagcccaa gaaatgggta ttccggtaat tacggaagtt gagctagctt
    27901 acgaagtagc ggaatgccca attattggga ttacaggaac gaacggaaaa acaacgacaa
    27961 caacgatgac aggactacta ctgaatgcag gagcagatca aggaattgca cgtttagcgg
    28021 gtaatattgg gtatccagca agtggtgtag cgcaagaagc aaaatcagaa gataaaattg
    28081 tgatggaatt gtctagcttc caactcatgg gaatcacaga tttccgccct catatagcgg
    28141 tgattaccaa tatctatgaa gcacatattg attatcatgg tacaagaaaa gaatatgtca
    28201 aagctaaatg gaaccttcaa aaaaacatga cagaaaaaga ttatctgatc cttaactgga
    28261 atcagtcaga actacaagaa ttagcgcaaa gaacaaaagc acgcgtactg cctttctcga
    28321 caaaagaagt gttggaagac ggtgtgtatg ctgacgatta ctcaatatac tataaaaaag
    28381 aaaaaataat ggaaatatct gaacttggcg taccaggtaa gcataatgta gaaaatgcac
    28441 tagctgctat ttctgtagca aaattgtatg gtatatcaaa tgaagctata cgagaaacgt
    28501 tgcatttttt ccatggcgta ccacatcgta cgcaatatgt aggagaaatc caaggcagaa
    28561 aattttataa tgattcaaaa gcaaccaata ttttagcgac taaaatggct ctaagtggat
    28621 ttgaaacgtc taaggtcgtg ttattggctg gcggattaga cagaggaaat acatttgatg
    28681 aattaattcc ttcattaaaa ggaatcaaag caatggtcgt atttggccaa acaaaagaaa
    28741 agttgatgga tgctggaaaa aaagcaggca tcgagacaat agtaacagcc gattctgtag
    28801 aacaagcagt tcctttagca ttagaaaaca gtacagatgg tgatgtagtt ttattatcac
    28861 cagcgaatgc cagctgggat caatacccaa attttgaaac tagaggaaac agattcatgg
    28921 aagctgtgaa ccgattaaaa tagaaaaagt agaagcgagc gataaaaaat gaaaattttg
    28981 gttacaggcg gaggaacagg gggacatatt tatccagctc ttgcctttgt caattatgta
    29041 aagactcaag aaccgaatgc tgaattcatg tatgtgggag caaaacgagg tctagaaaac
    29101 aaaatcgtcc ctgatacagg aatgcctttc cataccttgg agattcaagg atttaaacga
    29161 aaaatttcca tgcataacat caagacggtc cgattgtttc ttaagagtat ccgtcaagca
    29221 aaaaaaatcc tcagtgattt tcaaccagat atcgttatcg gtactggagg atatgtttcc
    29281 ggagcggtag tgtacgctgc agccaaaatg ggtattccaa cagttatcca tgaacaaaac
    29341 agtgtaccag gtgttaccaa taaattttta agccgatatg tggatcggat cgctctttca
    29401 tttaaagatg cggcttcctt ttttcctgaa aacaaagcag ttcttgtagg taatcctcga
    29461 gcacaagaag tagcagatac taaaaaatca gatattttga aaacatttga tttggatcca
    29521 gaaaagaaaa cagtcttgat ttttggcggt agtcaaggag cacttaaaat caatcaagca
    29581 gtatcagttt ttttaagtga atatattcct tcttcttacc aagttttgta tgcttcagga
    29641 gatagatatt atgaagagat cctaaataaa ataaatcctg aaatacaaaa tattagtgtc
    29701 cagccttata tcaaaaatat ggcagaggtc atggcttcca gtgatctgct ggtggggcgt
    29761 gctggtgcaa cttcgatcgc agaattcaca gctctggggt taccggcagt gttggttccc
    29821 agcccatatg ttacgaatga tcatcagact aaaaatgcaa tgagtcttgt tcacgcagga
    29881 gcagcaaaaa tgattgcaga taatgaacta acaggtgaat cactaagtca gacagtcaac
    29941 gaaatcatgg gtgatgaaga attgcaaaag caaatgtgcc gagcttctaa agaacaagga
    30001 atccctgatg cttcaaaacg tctttatgac ttagtaaaac aaataatcaa aaaataaagg
    30061 cggtggtctt agtgagtaag aaaaaagaac caaaaaaatt gtctcatccg tcttctgatg
    30121 aaaacaattt gactccttgg caaaaggcta accgaaaata tctggcagaa caagagatga
    30181 aaaaccaaga gccaaaaaaa gaagacataa cattagatac acccctttca gattctgaag
    30241 aagaaaaaac ggttcaagag gaacagcaag aagaaagcca gtccgagaaa aaaatcgaat
    30301 tttttgaaga gatcaagcaa aagaaaaacg gtggaccata taacggttct tttttgaacc
    30361 ggctgcccaa tttaaaaagt caacggcaca aagtactatt tcgtcggtta gctttgatca
    30421 tcactgtatt gggtataccg ctgatttttt tgatctatta tgtttctcct tatagcaaat
    30481 tacaagcagt tgcagtatca ggcaataaga cagtcaacag ccaagaaatc atctctgata
    30541 caaaattgtc attaggagaa aatgtttggg gacagtattt tcatcgatct acttatatcg
    30601 atcgccttaa aaaagcacag ccaagaatcg aaacagcaaa tatacatttc aaagggatga
    30661 atgaattcga tttggatgta acagaatata aagagattgc tttgatcgca aaaaacaatc
    30721 aatactaccc agtgattgaa aatggaacag tattagatga aaaagtagca aatcctacaa
    30781 aaaatctccc tatcttggaa gagttcaaag actctgcaaa aatcaaagaa ttaacaaagc
    30841 aatacaatca gttatcatca gaattacaaa aagcaatttc tgaaatcaag tacacgccaa
    30901 gagcaagcaa taaaaatctg atccaattga atatgaatga cggcaatcaa gttattgtaa
    30961 atatcaataa tcttgcgaac caaatgaaat attattcgca agtagccaaa gatatggatg
    31021 aaaaaggtgt gatcgacatg gaagttggta tcttctcgca tccttacggt agcactcaag
    31081 aaacggaaga atcgggccaa tcggaagaaa caactgaaag tgaagaaaat gcggatcaaa
    31141 caaacgaatc aagtgaagag gcagaaacgc aaaaagcaca aacacctgga tcgtctagca
    31201 caaacggatc atctgattca aatgattcaa gtgaaacaag tcaaatagaa gataatccaa
    31261 gtacaactcc gtcaagttta aatgaaaatt gataaaacaa ctttaaaaag taagaatgta
    31321 ctttctaaaa accagtaatt tatggtagaa ttggaagcag tgaatatatc tattaataag
    31381 tatattttaa aacggacgct agttgttcgc ttgtatatgg aatagtaagt aggagggaat
    31441 cccattcatg gcaaaaacag gaatgtatgt aggccttgat attggaacga catctgttaa
    31501 agttgtcgtg gctgaatata tcgacagcca aatgaatatt attggagtag gaaacgcaaa
    31561 atcagaaggg attaaccgag gcattatcgt tgatatcgat aaaacggtcc aagcgataca
    31621 acgagcagta cgacaagcag aagaaaaagc aggtatccag atcaaaggcg taagtgtcgg
    31681 tttgccagca aacatgcttg aagtagaaaa ttgccaggga atgattgcag ttaacggaga
    31741 ttcaaaggaa atcaccgatg aagatgtcag aaatgtggct tcagctgccc ttgttcgttc
    31801 aatacctcct gaacgtcaaa tcgtgtcaat attgccacaa gattttactg tcgatgggtt
    31861 cgagggaatc aaagatcctc gtggaatgat cggcgtaaga ttagaaatgt acggtctgtt
    31921 gtttacagga cctaaaacga tcatccataa catacgtaaa tgcgtggaaa atgccggatt
    31981 aatcgtcaac gaaatggtga ttactccttt agcgctgact gaatcaattc tttctgacgg
    32041 agaaaaagat tttggtacga tcgtcattga tatgggtggc ggccaaacaa caacggctgt
    32101 tatgcatgat aagcaattga agtttaccaa tcttgaccaa gaaggtggcg aatttgtcac
    32161 taaagatatc tctattgtat taaatacgtc atttaacaat gcagaagcgt tgaaaataaa
    32221 ctacggggat gcatacccag aacggacatc accagatgaa gaatttccag tagatgtgat
    32281 tggtcagtca gaaccagtga aagtcgatga acgctacttg tcagaaatta tttcagctcg
    32341 aatggaacag attttcaaca aagcaaaaga tgcattggac caaatcgaag cattagagtt
    32401 gccaggtggc gtcgtattga caggcggagc tgctagtctt cctggtgttg tggacttggc
    32461 acaagaaatc ttcggcgtaa atgtaaaatt gtatgttcca aatcacatgg ggctgagaaa
    32521 cccggtattt acaaatgtaa taagtatcgt ggattattca gcaaacttga gtgaagtgta
    32581 tcaattggca aaaattgctg ttacgggtga aacctcagca gctcgtcaaa tggtagttga
    32641 acaagaaaca acaaacacat atgagagcta tgaagcacct gaagaaacaa tctacgatga
    32701 gccggaacca aaagagtccg gagaaaatgt aaaaaataaa atcaagggtt tctttacaaa
    32761 tatttttgat taattcatcc tgggaggaat aagatatgga attctcaatt gataataata
    32821 tcaatgacgg cgcagtaatc aaagtcatcg gagtcggtgg tggcggtgga aatgctgtaa
    32881 accgaatgat tgaagaaaac gttaaaggtg ttgaattcat tacagccaac acagacgtgc
    32941 aagcattaaa aaattcaaaa gctgaaacag ttatccaatt aggccccaaa tatactcgtg
    33001 gtttaggtgc tggttctcag ccagaagttg gacaaaaagc ggcagaagaa agtgaacaat
    33061 ccttacgcga agctttagac ggtgcagata tgattttcat cactgcagga atgggtggag
    33121 gaaccggtac aggtgctgca ccaatcgttg caggtatcgc gaaagaattg ggcgcattga
    33181 ctgttggtgt cgtgacacgt ccattcactt ttgaaggacc gaaacgtggc cgttttgctg
    33241 cagaaggtat cgctcgtttg aaagaaaatg tggatacatt attaattatc tcaaataacc
    33301 gtttattaga agttgtagat aaaaagacac cgatgcttga agctttccgt gaagcagata
    33361 atgttttacg acaaggtgta caaggtatct ctgatttgat cacagcgcca ggttacgtta
    33421 accttgactt tgctgacgtg aaaacagtga tggaaaacca aggtacagca ttgatgggga
    33481 tcggtgtggc tagtggagaa gatcgcgtag tagaagcaac gaaaaaagca atctcctctc
    33541 cattgcttga aacatctatt gatggagctg aacaagtact tcttaacatc acaggcggtt
    33601 tggatatgac attgttcgaa gcacaagatg cttcagatat cgtagcaaat gcagcaactg
    33661 gcgatgtaaa tatcattcta ggtacatcta tcaatgaaga aatgggcgat gaaatccgtg
    33721 tgacggtcat cgcaacaggt atcgatgaat caaaaaagga acgcaagtct agccgaccag
    33781 ctagacaagc acaaatgcaa tcacctgctc aaaagactgt attagatatg gatcaagcta
    33841 aaccaacttc ttcagaagaa gaaaacagtt ttggcgattg ggatatcaga cgtgaacaaa
    33901 atgttcgtcc tagagttgat gattccaatt ttgacaatat cgaaaaaaaa gaatttgata
    33961 cattcaaccg cgaagaaaca aaatctcatg gcgatgatga attaaatacg ccaccgtttt
    34021 tccgtcgtaa aaaataaagg agaggaagag cacatgattg ctgacaactt gcagaaaatc
    34081 aagcaagaaa ttcaggattc gtgtgctctt gttcatcgtg atccgaaaga agttacatta
    34141 gtagctgtaa caaaatctgt tgaatccgct caagctgaag aattggttag agctggcgtt
    34201 atgaattgtg cagaaaaccg agtagataaa ttattagaaa agaaacaaga tttatttgat
    34261 tttcctgaaa taaagtggca tttaattggt aatttacagc gcagaaaggt aaaattgatt
    34321 gtaaatgaaa ttgattactt tcatgcgttg gacagtttaa gattagcaga agaaatccag
    34381 aagcggttag agaaagaatt atcctgtttt attgaagtaa atgtttctgg tgaggaatca
    34441 aaacatggaa tttcaccaga tgagctttta ccgtttgtgg aatctttagc tgcctgcaca
    34501 aaaatcaagg ttgttgggtt gatgactatg gcgcctaaag aagcttctga tgagcaaatc
    34561 cataaagtgt ttggtacgct gaaagaattg cgtgatcttg ttcaagcaaa aggttatgcc
    34621 catgcaccat gtagtgaatt aagtatgggg atgagtcaag actttcaaat tgcgattgaa
    34681 gaaggtgcaa catttatccg tgtaggaaca gcgctattca aagacgaata aaggaggaac
    34741 aaaaatgccg cttttaaaca gaggagcaat tgctaatttt ttcggattag ctgatgagga
    34801 agagtacgaa taccaagatt atcctgaaac aacaaaaaag gctgtacagc caactaaaaa
    34861 aaatacaaca cagaatcaat caactcattc tgtatctgct gcgaatactc atgaaaaaca
    34921 aaaaacggcg acttcacgtc ctgtaacgca tgaaagtatt cagccggctg aaaagaaaaa
    34981 agtaattgaa ctacatcaat cacctacaaa aactgtagcg aaagaaagaa cagcttcaag
    35041 aacctctaca caacctaaag caaatcttgc tggaaaaatc actgtaatgg aaccaagagc
    35101 ttattctgaa gctatggcga ttgctaaacg aatcattgct ggagaagcaa ccttagtgaa
    35161 ttttcattta gtagaagaaa aacaagcgag aagaatcgtt gattttctaa caggaacagt
    35221 ttatgcacta gatggagata tcaaacgtgt tggagatgag atttttcttt gtacaccgac
    35281 tgggatggag attgacagtt caaccgctca atcttttgca gatgcgaatt tgtttgatct
    35341 gtaagaggag gaactacgat ttatactatt gcactattac ttcatttact tcaacgggca
    35401 gcctatttct atagcattat cttgatggta tatgcattgc tctcttggtt tccaggcggg
    35461 tatcaatcag ggctaggacg attattagct aagatctgcg aaccgtatat cagtttgttc
    35521 gatcgtctgc ctttgaggat tggacccttg gatttcacaa ttttaggggc aatcctgatc
    35581 ttgaacttag ccgtacaagg tttagcacag atcgttatat ggataactgt ccatttagtt
    35641 tattgattga agcaacaaaa tctttattct cagaatagat aggaggggaa aattttggat
    35701 gcaaatgtat accagcactt tcgggcagat gaacgtacat ttatcgattc ggtaggcgat
    35761 tggattgaac aggttcaagg acaatatgca ccctatctga ccgaatttct tgacccaaga
    35821 caatcctata ttttagaaac actgattcga caaagcagtg atttgcgttt catgttttat
    35881 ggcggatatg aacaggcaga aagaaaaaga tgtttgattt tccccgatta ttacgaacct
    35941 gtagaggaag attttgaaac agcattgtat gaaatccatt atcctagcaa atttgccagc
    36001 ctaagtcatg ggaaaatcct tggaacttta gtgggaacgg ggatcaaacg ctcttacttt
    36061 ggcgatatca tctcggacgg tgatcgctgg caagtattta ttgcaaatga ggtggatcat
    36121 tttgttgctg cacaagtaac aaagattgga aaggttgctg tacgcttgga accaatcaaa
    36181 tacacagaaa tgattatgcc gaaagatagc tggacacaag aaagaggaac agttagttcc
    36241 atgcgactag acagtgtgat ctctgagatt tataatattt ccagacagcg gtccaagcag
    36301 ctgatcgaag ctggtaaagt aaaagtgaac tggacagaaa atacaagacc tgattttgta
    36361 cttgaactat tagatattat ttcagtcaga ggttatggca gagtccagat ccaagaactt
    36421 gaggggaaga cgaaaaaaga aaagtacagg gtactgttcg gtgtattacg taaataaaat
    36481 aaaaaggtgg tttactcatg gctttaactc cattagatat ccaaaataag acattcccga
    36541 caaaaatgcg gggatataat caagacgaag tagatgattt cttagattta gttgttcgtg
    36601 actatgagga attgactcaa agaaatcgag aattagaaaa agcagtcaaa cattctgaag
    36661 aaaaacttga gtacttcaat gaattaaaag atgctttgaa ccaatcaatc atcgtagctc
    36721 aagatacggc tgataaagta aaaacaagtg caagcaagga atccgaagtg atcgttactt
    36781 ctgcacaaaa caaagcagat gagttagttg cgaacgctga aaaacgtgca catcaattaa
    36841 caactgatgc agaagaaaaa gcaagaaaaa tcttgacaga tgcaacagaa aaagcaagac
    36901 agcttgcgac agaaactgaa gatcttaaga aaaaaacacg agtattccat caacgtatca
    36961 gcttgatgct tgagtctcaa ttagaacaag tgaaaagtcc ggaatgggat gaaattttac
    37021 aaccattctc cagctacgtg actgacagcc atgaagtgat caaagaagtt ttagcaaaac
    37081 agcttgacaa tgaaaatgat actgatgtaa actcagacac aggagtcata gaagcaccta
    37141 tgacggcatt tgatacacag gctattgata tctcgatcgt gcctggtgaa aatgaaaacg
    37201 agtagaacag aaaagcactt tgttattctt aaagcgagcc gatgagagtg gaagttcggt
    37261 aagacactgc atggtgaaag atcctctact tgagacctgc ttttccgaaa ttagagtaag
    37321 aagcagcggc tgacctcgtt attggtcaca gagagtttgc actagataga tgcaactaaa
    37381 tttgggtggt accacggcat gttcgtccct tgcggctgaa catgcttttt tgtgtccgga
    37441 aaacaaataa aggagtgtat ggttgaatga aaatgaaaga aaccttgcaa ttaggaaaaa
    37501 caaaattccc tatgcgtggt aatttgccaa accgagaagg cgagtggcaa aaagaatggg
    37561 aagaaaatcg aatctaccaa aaaagacaag agttgaacga aggaaaacct agctttgttc
    37621 ttcatgatgg acctccatat gccaatggta atatccattt aggacattca ttgaataaaa
    37681 tcagtaaaga cattatcatt cgttcaaaat caatgtctgg ctatcgtgca ccatatgttc
    37741 caggatggga tacacatgga ttgccgattg aacaagtatt ggctaataaa ggcgtgaaac
    37801 gtaaagaaat gtccatggca gaatacttgg aaaaatgtcg tgaatatgca ctttcccaag
    37861 tagataagca acgagcagat ttcaaacgcc taggagttgc aggagattgg gaacatcctt
    37921 atgttacatt agatccttct tatgaagctg cacaagtacg cgtatttggt aaaatggctg
    37981 aaaaaggcta tatttacaaa ggattgaaac caatttactg gtctccgtca agtgagtctt
    38041 ctttagcgga agctgaaatt gaatataaag atgtaaaatc tccatctatt tttgtagctt
    38101 tcaatgtcaa agacggcaaa gatattcttg atgaagatac agcttttgtc atttggacga
    38161 caacaccatg gacattgcca gcaaaccaag gtattgctgt aaatccaaaa tttacgtatg
    38221 tattggtgga agccgatggc cgtaagtttg tcgtagcgaa agatttgcta gaaacagtcc
    38281 aatcagaaat cggttgggaa aatgtaacag ttctaaaaga atttgctgga caagaaatgg
    38341 aatatatgac tgcaagtcat ccattctatg aacgtgaatc acttgtgatt ttaggcgatc
    38401 atgttacttt agacgctggt actggattag tccatactgc tccaggacat ggggaagatg
    38461 actatatcgc tggtagcaaa tataaactat ctgtagtgtc acctgtagac tcaaaaggat
    38521 tgtttacaga agaagcacct ggatttgaag gtatctttta tgacaaagca aatcctatga
    38581 tcactgatct attaaaagaa aaaggagctt tgctgaagct agatttcttt actcatagtt
    38641 atcctcacga ttggcggacg aaaaagcctg tgatctatcg ggcaactcca caatggtttg
    38701 catctatcga taaattccgt cagaatattt tggatgaagt agaaaaagta gagtgggtta
    38761 tcccatgggg taaaacacgt ttgtataata tgatccgtga ccgcggcgat tgggtaattt
    38821 cccgtcagcg tgcatgggga gtaccacttc cgattttcta tgctgaaaat ggagaagcaa
    38881 tcatcacacc agaaacaatc gaacatgtgg caaaattatt tgctgaacat ggatcaatta
    38941 tctggtttga aaaagaagcg aaagaacttc ttcctgaagg atttacccac ccaggttctc
    39001 ctaatggcga atttacaaaa gaaaaagata tcatggatgt ctggtttgat tctggttctt
    39061 ctcatgaagc tgttttacgt cagcgaccag aattatcatt cccagcagat atgtatttag
    39121 aaggatcaga ccaatatcgt ggctggttca actcaagtat cacgactagt gtggctatca
    39181 atggtgtagc accatacaaa tcagttattt ctcaaggatt tgctttagat ggtgaaggcc
    39241 gtaagatgag taaatcttta ggaaacatca ttgcaccaga aaaagtgatc aaacaatttg
    39301 gtgcagatat ccttcgctta tgggtatcta gtgtagatta tgaagcagat gttcgtgttt
    39361 ctatggatat cttaagtcaa gtggcagaag tatatcgtaa aatcagaaat acgatgcgtt
    39421 tcttattagc gaatacagaa gatttcgatc ctaaaaaaga tactgtttcg tacaatgatt
    39481 tacgttctgt agacaaatat atgaccgttc gattgaacca agtaatcaaa gaaatccgag
    39541 aagaagggta cgacaaatat aacttcatgc atatttaccg tacagttatg aacttcttga
    39601 cggttgatct atcgtcattc tacctggatt ttgctaaaga tgtagtttat attgaagcag
    39661 aagatgatta tcaacgtcgt tgcatgcaaa ctgttttcta tcaaacagct gtagctttga
    39721 caaaattatt gactcctatc attccgcata cagcagaaga aatctggtca ttcctgaaag
    39781 aagaagagga gtacgttcag ttaagcgagt ttcctggtta tgaagagttt gcaaaccaag
    39841 aagaattgat ggatacctgg actgctttca tggacttccg tgataatgtc ttaaaagcat
    39901 tggaagaagc aagaaacagc aaattgattg gtaaatcttt ggaagcaaaa ctaactgttt
    39961 atccaaaaca acaagttcgt gaaatgttaa aagctttgga tgcagatatt gcacaattat
    40021 tgatcgtttc accagactac tttgaagtta tggcagcaga tgaacaagtg ccagataacg
    40081 ctatggtatt tgatgatgtt gctattacag tggaaaaagc agacggggaa acttgcgatc
    40141 gctgtcgcca agttcgtaaa gatgtaggag tagatgaaaa acttcctcat ctatgcggtc
    40201 gttgtgcaaa aatcgttgaa gacttctatc ctgaagctgt agctgaagga ttcgaagaaa
    40261 agtaaaaggg aaaagggggt gtgacatgtt ctttgtcaca cccccttttg ttatcaatcg
    40321 tttaattttc cacgttcacg ataccagtta tctggttgcc agatccattc gaatccgtct
    40381 ttttcaagta gttcgaaagc tgctttaggt cccattgatc cagctttgta gttgggaaaa
    40441 tccggttgtg tttggtccca agcttttcga atgacatcca cgatatgcca agattgagcg
    40501 acttcttccc aatgagagaa gttcgttcca tcaccattca acgcatctaa tagtaatttt
    40561 tcgtaagctt ctgggctatt ttcaaccatt tctgcactat ttctaaattc caatttgatt
    40621 ggttccgttt caaatccttg ccctacttct ttcccattca aggataaaga aaatccttca
    40681 gttggctgaa tatagatcgt tagaacatta ggtggaagtg tcgtatcgtc acatggttca
    40741 tcgacagatg ttttgaatac attaacagga acttgtttga atacgatgtt gatccgagtc
    40801 cctttttcag tcaaacgttt gcctgtacgt acatagaaag gaacacctga ccaacggaag
    40861 ttatcgatag tgaatttgcc tgcgacgaat gtttcagtct ctgattgagc atccactttg
    40921 tcttcttcgc gatagccctt gaattgtaca ccatccaatt caccttgagc atattgcccg
    40981 cgaacgaagt tttctaacac ttcttcttcg ttataaatgc ggatagcttt caatgctttg
    41041 atcttttctg tacggatttc tttttcggaa aatgctactg gcggttccat tgcaagtaat
    41101 gctacaacct gtaaaatatg attttgcacc atgtctttaa gtgcgccact atgatcgtag
    41161 tagcccccgc gatcttctac accgaggttt tcgccaaaag taatttggat attgtcgata
    41221 tagcgattgt tccattgagc ctcaaaaata ttattggcaa aacggatagc tgagatgttt
    41281 tggatcattt cttttcctaa ataatgatca atcctgaaaa tatcttgttc tgggaatact
    41341 tctctgattt gctggttcaa ttcaaaagca gactggtaat cagaaccgaa cggtttttct
    41401 atgatcaaac gattgaagcc attttttgtc ataatatttt gtgatttcaa atgagaaacg
    41461 atcgttccaa aaaattgagg tgccatagcc aaataataga cacggttacc gtttaattga
    41521 tagtgtccat ctaatcggtc agacaattct tttaatgtct gataatgcgt tgaatcattt
    41581 acatcatggg attgatagta aaaatggctt gcaaaggtag ttgcttcttc atctgaagga
    41641 ttcaatgcac ggattgtttc tttgacaact tcacggtagt gctcatcgct ccagggacgg
    41701 cgagcggttc cgattacagc aaaatgctcg cctaaatttc cttttctgta aaggcggaac
    41761 aaagacgggt acaatttacg ctgggctagg tcacctgtac cgccgaatat cgtaaacaat
    41821 acattttttt cattagacat gtggatacac tcctttatat tttatcgaca aaaatcgtgc
    41881 tggccgcctt aaagctgacg gggattttct ttctatcatt ttggatagtg atcggtcctt
    41941 cataagctgc gatgtcaacg atctcatatt cttcgttgat attcaggtca atagtgacta
    42001 agtaatccaa caattctttt tcatcaagca ctcgtgcgat acgcactttt gtaccgacag
    42061 gataggactc caatgtttgt cggcgttctt catggacaac ttcctctttt ttaggaatcg
    42121 atcctccatg aggacaatgt tcaggatgat tcaaatagtt ttctaaatga tctgcaagat
    42181 gttccgaagt cacatgttcc aatacttcag catcatcatg gacttcattc cagctatagt
    42241 ctaaatgttc aactaaaaaa acttcccata agcgatgttt gcgaatcaga ctgctagctt
    42301 tttgcagtcc gcttgcagtc aattgtacac cttgataagg ggaatgttct acaagctctt
    42361 ctttcacaag tttagaaatc atttcactga cagatgcagc tgagacatct agactagata
    42421 cgatttgttt attgttgact ttcgttgtat ctccacctag ttctaaaatg attttcaaat
    42481 aatcttctcg atttggtgtc atattcgatc atcctttcat ggtaaaaaac catcattagt
    42541 aagtgtaaca aaaaaaacgt taattgacta tttttctaaa taaaaaacaa aggattttta
    42601 gacgttttta caacaaaaaa cgaaagatga tagagaagac tcattctttc gtttataaag
    42661 gatatatata tacattggga gggatctatt tttcagataa caacttatat gaagtgtctg
    42721 cagattcgtc ataaagagtt tgttcgggat aagaaaagat aagataaaaa ccatactgat
    42781 cacgtacgac taaacgatat tcatctattt ctaccacaga tgtgccaaga gactgaccgt
    42841 tgatcaaaaa cgtgtaatca gatgtaatct gtaattgttg tttttgctgg ctatcactaa
    42901 agaaccatgt accttgatac tttgagagtc cttctgactt ttccgcttgt tttttctttt
    42961 tcaagtaaat aaaacttgag agaacggtaa tgagtgaacc aagaaaatag atcatttttt
    43021 ttatcaccaa atcactcctt tatgagaaaa taatcgcata gacatattct ttcttcttta
    43081 tttcattgta ccgaataaaa gctaaaattt ctctaagact ttcgactggt ttttttactg
    43141 tttttctaca aattatgata ggatacatag taggaagaaa ggtgacataa tttgaagtat
    43201 cagcaagtgg aaatagcttt ttttattgac cgcccgaatc ggtttatagc acattgtatg
    43261 aaaaaagacg gagaaataat tattgcgcat gtcaaaaata caggtagagg aaaagaggtc
    43321 ctgataccag gcgctgaagt ggctattgta tttgctcctg gacctaaacg gaaaaccgcc
    43381 tatgatctga ttgctgtaaa aaagaagggt gactggttta atatcgatag tcaattgcct
    43441 aatcggctgg caattgatgg tattttagac ggcacgatcc ttttaccagg attaactggt
    43501 ccatttacgg tatacaagcg tgaagtaact tatcttcact ccaaatttga tatttattta
    43561 gagacggtgg tcggacaaaa agcatttgtt gaagtcaaag gtatgacact tgaaaataaa
    43621 gcgattggtg cttttcctga tgcgcccaca ctcagaggat tgaaacatat aggagaatta
    43681 acgtatgccg cacaagatgg ttatgccgct tatgtcttgt ttattgctca gttcgaacat
    43741 cttcatctgg caacgatcca tgaagaaatg caaccagcac tagctgatat ggttcgacat
    43801 gcgcagcaaa gcggagttca aatcctcgcc tataattgtc aagtatcggc agatgaggta
    43861 actgtcaagc aggccattcc atttgatgta gatatccctt ttgaagatcc tatacaatag
    43921 aaagaaggta aaataatgat caacttaggt attatcggaa caaattggat tactcatcaa
    43981 tttgtccaag cagctttaag cacaaaaaaa tatgaattga cagcggtata ttctagacat
    44041 ttggaaaaag cacaggaatt tggttctcat tatgaagggg atatcgaatt cgcaacagat
    44101 ttgaagactt ttttcaatat tactcatatg gacaccattt atattgcttc tccgaatagt
    44161 cttcacttta gtcaagctaa gcaagcaatt ttggcaggaa aaaatgtgat agttgaaaag
    44221 ccagcttttt cgacgccaaa agaaatggat gaaatcatcc atttggcaaa tgaacacaat
    44281 gtgtattttt ttgaagcagc aagaaatatc catgaatcag gttttaaaaa gattgccgat
    44341 tacttaccat taaaagacga gataatcggt gcaaatttca gctatatgaa atattcttcg
    44401 cgctatgacc aagtattaga tggagaagaa ccgaatatct tctcgactca tttctcaggt
    44461 ggtgcattga tggatttagg tgtttacctt gtatatgcag ctgttgcttg gtttggaatg
    44521 ccaaaagaag tccattattt cccaagaaag atttctactg gtgtagatgg tcttggatgg
    44581 gggatcttac gttatgagaa ttttgatgta tcgatccagc caggtaaaat cggtgattct
    44641 tatttaccgt cagagattta ttttgactca ggaacgctag tgatgaatgg agtcaatgca
    44701 attgaacaag cacaatttca tgatcgcgcg cataaagaaa tcattgattt ggcggtaaca
    44761 gctgcagaaa atccaatggc agatgaagca gaggattttg ccaatgtcat ggctcatccg
    44821 aaagatccag cttggggatt gttgtatgaa gagtggatcg agctagctag aaatgtgaac
    44881 caagtgattt atgatttaag aaaaaatggc ggcatcaaat tcgatgcaga taatgaggaa
    44941 gatttttaat gaacgaattt gtacaagtat ttcccgaaaa ttggcagaaa aaatatgagg
    45001 ataaagggtt tatctcacct tctcttattc aacgagcagt ttttcagcca ctaagtaata
    45061 aacaaagtat agtagcggtt tctcctacag gttcaggtaa aacactggct tatctttggc
    45121 ctctactact aaacgtggaa ccaggtgaag caagtgcgtt ggtcattttt gcttcttctc
    45181 aagaactagc tattcaagta gcagatgttg cacgtgaatg gggaaaagac aaagagttga
    45241 aagtccaatc tttggtgggc ggagccaacg tcaaacgtca gattgagggt ttgaaggaaa
    45301 aaccagaaat cttgattggt acaccaggaa gaatattgga attgatgaaa gcaaaaaaaa
    45361 taaaagcaca tcaagtgaaa acaatggtat ttgatgaagc agaccagcta tttgacgctg
    45421 ggaacagcca aatcattgat caaattcttc atcaagctcc aacagagtat cagctagctt
    45481 ttttttcagc gacagcagat cgttcccttg aaagcattga aaaaatcact gggaaaacgt
    45541 ttgagacaat tgacgtgaca gcagaggacg attctcgaaa aggactgaga cattactttt
    45601 tacgtgtacc gatacgaaag aaagatgact acttgagacg tctcacgcat atagaagatt
    45661 ttcatggtct gattttcttt aatcaactga ctgaattagg cgtaatggaa gaaaaattgc
    45721 tgtatagagg tgtaccggta ggaagtctgg cctctgatca gaacaagcta ctccgaaaag
    45781 cagcgctaga acaattcaaa aagaaaatgg tcagagcact tttgaccaca gatgtggcgg
    45841 ctagaggttt agatattaca ggtcttcctt atgtagtgaa tgcagaagtt ccgttaagtg
    45901 aagaagctta tttgcatcgt tcgggaagaa ctggtcgaat gggtaatgaa ggaatagtaa
    45961 ttacactcgt acaagataat aatctaagag atttaaaacg gcttttacgt ccatcaaata
    46021 taacacttga agagattttt ttatacggag gtaagctgca aactgagcag ccaaccaaag
    46081 aagatgcagc tcctgcagta aataaaaagt atgcgaaaac tttttctgga aaggagcaga
    46141 acccagaata taacaaagaa aaaataagaa aaaaagttaa aaataaatca aaaaaagaga
    46201 gaaataaagg agcaaggcgc aaataagcgc ctttttatgc tatgattatg aaaacgggaa
    46261 caaaattggt tgccagagga ggggttatgt gaaagaacgt caagaagaga tcttgcagct
    46321 attgacagaa aaccaacaag gattgacagc aagtgatgta gctgagcgct taactatcga
    46381 tcgaagcaat gcaagccgat atttaagtga actatacaag gcccatcata ttgtaaaaac
    46441 cgctggccga ccagtcgttt actctttgcc aacggaaaag tcaaaatctg atgaagtgca
    46501 tgtcgactct tctacgcaag tgacttttga aacactcgtt ggagaaaatg attctttaaa
    46561 agtcagcata cagcaggcaa aagctgcgat tctttatcca ccgcgggggt tgcatacgat
    46621 tatttttgga gaaactggta cagggaagtc gatgtttgct gaatgtatgt atcattttgc
    46681 aatcgattca gagatgcttt ctgcagatgc gccatttgtt tctttcaatt gtgcggatta
    46741 tgctcaaaat ccgcaactgc tctttggaca catctttggg atcaaaaaag gggcttacac
    46801 aggagcagct caagatagtc ccggtctaat agccaaagca gacggcggta tattgttttt
    46861 agatgagatc caccgtttac cgccggaagg gcaggaaatg ctgtttactt tcattgataa
    46921 aggtatttac cgtccgcttg gagaaagtgc acaagtacat gaagcatctg ttcagatcat
    46981 tggggcgacg actgaatctt cagaaagttt cttatctacg ttcaatcgac ggattcctat
    47041 ggcaatcacc ttgccgaatc ttgcttcacg ttcactggat gagcgttatg aaatcatctc
    47101 tctttttatc aaacaagaag cgaatcgttt gaatcaacgt atcgatatcg aaaaagaagc
    47161 gattcttgcc ttcatgcttt atgatgcgga aggaaatatc ggtcaagtga aacgagactt
    47221 gaaactagtc tgtgcaaaat cttttttaca ttaccgtact catcatgaga aaaagctaat
    47281 cattcgaaaa gaagaacttt cccttcaagt acaaaaagga ttactgaaaa tcaaggaaat
    47341 accggaacgt ctcgaccgat tcatggacag caaaagtcag tatttgacat ttgaaccagg
    47401 atttgctgat gttgtctggt cacaagatcc agaacgaaac atgcaggtct ataacgatat
    47461 tgaggaaaaa gtcacttctc tttccgaaac cggtgtggag aacattgatc tagagaccct
    47521 catttcaaaa gatgtggatg cttatttcca gacatatgtc aaagaattga ctaaaagttc
    47581 gattcccaaa gatcttttgc cagatgaaat ctggcggtta accaatcaat tgtatgatgt
    47641 ggctgaaaaa cggttagacc gtatttataa tgaaaaagct cgttttgctt ttgctttgca
    47701 tctgcaaagt acattggatc gtgtgagaga aggtcatatg atcgtccacc cagatttgaa
    47761 taacgtacgg aaaaatttta agagggaatt ccaggtagca atcgatcttt caacgatcat
    47821 tgaagaagaa gaacaagttg agattccttt tgatgaaatc ggctttatta gtatgtttct
    47881 ttctatcaat ctaggagaaa gtgagcctgt taaagaaaac aaagtagatg ttctcatatt
    47941 gatgcacggc agacagactg cttcaagcat gttggagatg gcacaagaac tattaggaac
    48001 aaaagtaggg aaagctttta atatgccact ggttatggaa gttcaaacaa tgtatgaaga
    48061 agtgttacaa tatgtcaaaa actatcaaga gcatttgacg aatggcctac tcttgttaac
    48121 agatatggga tcattaaaca ccttcagtga tttgatttat gaagagactg gcattcggac
    48181 gaaagctatc acgatgacaa gtaccatgat tgtgatagaa gcgatacgga tggcaagtgt
    48241 tggaagaagc ttagaagata tttatcaaaa tatccagctt tcctttgaat cgatcgtacg
    48301 tgatcagttc aaagcggaaa agtctgaaac tttacagcgt aaaaaagccg taatcgtgac
    48361 atgctttact ggtgaaggag tagctgccaa attatatcag cgtattatgc cagtgattaa
    48421 tcaaaataag gtagaactga tccagatgca gtttttagaa cgtgaatcat tcaaaaaaca
    48481 catcgatgcc ttattggaag aatatgagat caaagcaatt gcgggaacag ttgatgttga
    48541 ttatcaaaat atcccatttt tttcagccta tgacgttttt gatgatgaaa aactaaatat
    48601 tttaaagcgt atagctgatg atgagatccc gacagctaaa attgtcgatt cacttgctgg
    48661 atcattaagc gatgtctttt ctattgatga actgatccgt tcattgcaaa agacagttca
    48721 gcagatccag accgatttgt cgattatcgt ggaacctgga gtagatactg gaatcgttat
    48781 ccatttagcc ttcatgttag acggattgat caaacaagaa agccatcggc aatttgagaa
    48841 actgtctatt ttctcaaaaa tttatcgttt ggaaatggat atcgttcggg caaacttgat
    48901 ggcactagaa cgaaaatatc aggtaaaaat tccagaagat gatatcgcat ttcttacaca
    48961 aatgtttctt gaaaataaaa taaaaaaatg aacacactaa tcatactgtt tacacactaa
    49021 acatctgtgt gcgcactata aaaaagagct aaaaagcatg aaaacgctat ttcagctctt
    49081 ttttttattg gcatgcttct tgcgttatat aaaagtgtaa aaaaataaaa ggagtgttaa
    49141 aaatggcaaa aaaaacaatc atgttagttt gttcagcagg gatgagtacg agtttattgg
    49201 tcacaaaaat gcaaaaagca gcagaagaaa aagggatgga agccgatatt tttgcggtct
    49261 ctgcctcaga tgcagataat aatttagaat ctaagaatgt cgatgtatta ttattaggtc
    49321 ctcaagtacg tttcatgaaa gctcaatttg aacaaaaact tgcgcctaaa ggtattccat
    49381 tagatgtcat caatatgcaa gactatggca tgatgaacgg agaaaaagtt cttgcacaag
    49441 cagaaaatct aatgaaataa atcaagtatg cagttggggg tataacaacg tggaagatca
    49501 acaaaatcta gaagccatca tggggttaat catgtttggc ggtaatgcaa agagcgatgc
    49561 aatggaagcg attgcggctg ctaaaatcgg tgattttgag ttagcggata ggaaaatcgc
    49621 tgatgcagaa gaatcactta tacaagcgca tcatgcacaa acagacatgt tgacacaaga
    49681 agcacaagga aatcatatgc aagtgacatt attgactgtt cacagtcaag atcacttaat
    49741 gacatctatt gcgtttactg atttagcaaa agaaatcatc gaactttatc gtcgcgtata
    49801 cagcgaataa atacaacttc ttttttgaac ggaagaagaa aaatttttga acggattttt
    49861 tattttgtta taaggagaac tctctttata taaaaaactt ataggaggaa gtaaaaaatg
    49921 aacggactat caagttggat ggagaaatac atcctgccgg ttgccgcaaa aatcggagcg
    49981 caaaaacatt tagttgcttt gcgtgatgct tttatcggca tactgcccgc aacaatggcg
    50041 ggatcagtcg ctgtaatgat caatgcaatt attcgtgatt taccgcaaca gtttaacagt
    50101 acctatgctg acagtttagc agcagacaaa ggaatctttg ccgtattgaa tgtcatcatc
    50161 ggaatcaatg gttttgtctg gaacggtaca ctagcaatcg ccggattgat ctttgccttt
    50221 tcttgggggt ataatcttgc ccgagcttat ggagtaaatg atctagctgg ggggatcgtt
    50281 ggtttagcta ccttgattca aggtatttcc tttggtccag cattatcagc agcattagat
    50341 gtgaatgttc cttcaaatgt cgcagatgca atcaatagtt ctgagattgg tgcaacgatt
    50401 gcagatggca cactgtcagt tggattatgg ggttggctaa aactagatca tttgaatgga
    50461 aacgcttatt ttacagttat gatcatggga gctatttcag tcattatttt ttgtaaattg
    50521 atgcttgcca acattacgat caaaatgcct gattcagtac caccagcagt atctaaagca
    50581 tttgcagcca ttttaccagc gacgatcgct ttatacgtca ttgctattat caattatatc
    50641 gtaggtcgtg tagctgatgg gcaactgatc attgatttgg tgcaaaaata tattgcagaa
    50701 ccattcctag ggttatctca agggttggga gcagtattga tcgtcacagt atttgttcaa
    50761 gtattctggt tctttggtat tcatggatca aatgtattgg caccagtgct agagggaatc
    50821 tggggacaag cacaactaat caatattgat attttccaaa aaggttataa cggaaaaact
    50881 ggtacaccag ccgtgttaga tgcaatcgaa gatggaaaag cttatatgtg ggtccgcgga
    50941 tcgttcgatg cttttgcatg gtttggcgga tcaggcggaa cgatcgtctt actgatagct
    51001 atcttgattt tctctaaacg tgcagattat ctaacagtag ctaaattatc cattgggcct
    51061 ggtatcttca atatcaacga accagtgatg tttggtctgc caatcgtatt gaatgcaatc
    51121 atgtttatcc cattcttgat tgctccagta gtagcaacag caattggatg gacagctact
    51181 tatcttggcc tagtcgctcc ggtatcgcag caagtcacat gggtagtacc gccgttctta
    51241 ttgtcattct tagcaacagg agcggattgg cgggcaccga tcgtaacatt agtatgtatg
    51301 gtcgtgactt tcttgatttg ggcaccattt gtcatctctg caaacaaaat ggaccctgcc
    51361 gcaggcgaac aacaataaga tgaacgtgag gagcgggacg ctttaagttt cgttcctcat
    51421 aatgaatttt cgaggaggaa ctgaaatgat tacaattgcc agtgcaatgc aacaagatga
    51481 aatcaaagaa ttgttagaag gatacaatga agaaggaatg acttttacat ttaaagaaaa
    51541 acaaggaatc aagctgttct ttgaaacaag tgcagaagat ccggaagttg cggctaaaaa
    51601 agcaaaggaa ctaatcaaag cacagccttg gggaacagtc ctttattttc aatcaacagc
    51661 tgtttagaaa atggtttaaa aagataggat ggttgagatg ataaaaaacg gtttattttt
    51721 atgtagtatt ggttctttga tcgtgttgta tagtttgaat ccacattcgc aaaggtatga
    51781 tttgtatagt atggtcacag gtctttttct aacaggatta ggaatctatt tcttcatgaa
    51841 ggggaaaaaa agagaagaag caaaggagaa aaataactaa tggaaatcac gaaaaaatta
    51901 aatattccag catcgttttt ttacgataaa gttatggact ctgtcctttt cgatgtacgt
    51961 aaagcgaccg gcaaatcagt aactagaaaa cagctgaaaa atttggagta cgtcaaacaa
    52021 ttctcgcaaa ataaccgggc tcgcataaaa atcgaagaag tcattgaaaa ccagtcttat
    52081 aagtttcgta catcgacaac gaagaatgaa ttcgtcgttc attatcaaat caaaccattg
    52141 gacgattcga cctgtgaggt tcattacaca gaaaaaatgg agtcttatgg catgcttcaa
    52201 aagttgaatg atatgctttt aggaacaatc ttgatgtatt ttaaacggag acgtttcaaa
    52261 aaaatgctag atatgatcga agcaacgtat taaatcaatg aaacatggta ctatttagtt
    52321 attgaaaaat gaagtaagct agaaggaatt tttcatagga agatagatct ttcctgcgaa
    52381 tcctcactag cttttttgta ggaaggggca gcaaaatgac aaacaaagta agagagctag
    52441 gtgtatcttc gattgaggaa atgtttgatt tagccactta tgcatttaat ggggcagata
    52501 cacctgaaag gcgagaacgt tttcgtacac ttgcggagaa ttcttggaat tacggatttt
    52561 ttgatgagga ggatcggcta acaagtcaag tcatggcgac cccttttcca gtgaattttt
    52621 acggacaaga gtacctaatg gccggcattg gctatgttgc ttcttatcca gaagcaaggg
    52681 gacaaggcgg gatcaatcag atcatggaaa agatccttga agattgccgt gatcgtaaag
    52741 taagcttatc ttatctggcg ccattctcct atcccttcta tcggcgctat ggctatgaac
    52801 aatcatttga taaaatcagt tatcaactaa acagtcgtga tgtgccgttt atcaaaaaaa
    52861 aatctggaaa aataaagcgt atggattttg aagatgcaaa agctgcaatc agaagaattt
    52921 atgaacagat gccggaaaac caacgagctg gtctgaagcg cgaagactgg tggtatacgt
    52981 ataaattcaa gcaaaaaggc aattaccagt ttgctttgca ttttgatgat aatgaggaag
    53041 caacgggata tatcgtttat cagcttgcaa cgtcttcctt tattattgcg gagtggggat
    53101 ttttggatca tgatgctttt tgcagccttg ttcgcttcgt aagttctcac aatggtgctt
    53161 ttgaaacatt tgaatattca tgcggctacg gcggtaatga tcaaaattat ctattagaaa
    53221 atccatttgc ttctgtaatg atcacacctt atatgatggc gaggatcgta gatatttctt
    53281 tgtttttgga aaattatcca tttaaaaaga gacaagctgc atttgcccta caaatagaag
    53341 aagatcatta tgcgaaatgg aatgaaggaa tcgtggaagt aacaatcgaa aatggaaaaa
    53401 atcatctctc aaaagtagaa caaacaaaac tcccaatcgt tcgaggaagt atccaacata
    53461 tcacgcagct attattaggg tatcgtaaag tggaagagtt ggtattccaa gaaagaatac
    53521 aggtgacaaa agaatatgaa gaaacgttaa gctcaatctt gccacagcaa cagccaattc
    53581 ttaatgacta tttttgataa aaaacgggtg atgacaatat ttttgtcacc acccttttgt
    53641 ttttcatttg gcatttgaag gaaaatgtta aagtaaatcc tcttttttcg taaatttgaa
    53701 ttttttgttt tcttttgttt tagggttttc ttttttgtgg tcttggattg cttctttcgt
    53761 aatcttttcc cgattttttt tagatgaatc taagcgttct gcgtatactt tttcttttgg
    53821 cttatcattc attggaaagg acctccctac attatttcat tctacctcta gtttatcatc
    53881 tgttaaggac tagtggaaac gttttgccta acttataagc tgattttttt agcagataag
    53941 cttgcaagta aaaaacaaac aagctacaat tgatttattg aaattgttcc tgtagctcag
    54001 taggatagag caatcgcctc ctaagcgata ggtcgctggt tcaat
//
LOCUS       DAFLWQ010000008        51980 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.009, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000008 DAFLWQ010000000
VERSION     DAFLWQ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.009"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            186..524
                     /locus_tag="L1V16_000486"
     CDS             186..524
                     /locus_tag="L1V16_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274851.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            618..848
                     /locus_tag="L1V16_000487"
     CDS             618..848
                     /locus_tag="L1V16_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274852.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            1248..1619
                     /locus_tag="L1V16_000488"
     CDS             1248..1619
                     /locus_tag="L1V16_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBN1274853.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(1893..2585)
                     /locus_tag="L1V16_000489"
     CDS             complement(1893..2585)
                     /locus_tag="L1V16_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBN1274854.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(2588..3373)
                     /locus_tag="L1V16_000490"
     CDS             complement(2588..3373)
                     /locus_tag="L1V16_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1274855.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            3610..5010
                     /gene="lacG"
                     /locus_tag="L1V16_000491"
     CDS             3610..5010
                     /gene="lacG"
                     /locus_tag="L1V16_000491"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBN1274856.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            5035..5352
                     /locus_tag="L1V16_000492"
     CDS             5035..5352
                     /locus_tag="L1V16_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBN1274857.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            5365..7038
                     /locus_tag="L1V16_000493"
     CDS             5365..7038
                     /locus_tag="L1V16_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBN1274858.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            7052..8683
                     /locus_tag="L1V16_000494"
     CDS             7052..8683
                     /locus_tag="L1V16_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HBN1274859.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(9174..10739)
                     /gene="guaA"
                     /locus_tag="L1V16_000495"
     CDS             complement(9174..10739)
                     /gene="guaA"
                     /locus_tag="L1V16_000495"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBN1274860.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(10798..11721)
                     /locus_tag="L1V16_000496"
     CDS             complement(10798..11721)
                     /locus_tag="L1V16_000496"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBN1274861.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            11917..12522
                     /locus_tag="L1V16_000497"
     CDS             11917..12522
                     /locus_tag="L1V16_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1274862.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            12830..13846
                     /locus_tag="L1V16_000498"
     CDS             12830..13846
                     /locus_tag="L1V16_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBN1274863.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            13987..15288
                     /locus_tag="L1V16_000499"
     CDS             13987..15288
                     /locus_tag="L1V16_000499"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBN1274864.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            15334..15996
                     /gene="deoC"
                     /locus_tag="L1V16_000500"
     CDS             15334..15996
                     /gene="deoC"
                     /locus_tag="L1V16_000500"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBN1274865.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            16017..16415
                     /locus_tag="L1V16_000501"
     CDS             16017..16415
                     /locus_tag="L1V16_000501"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBN1274866.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            16481..17563
                     /locus_tag="L1V16_000502"
     CDS             16481..17563
                     /locus_tag="L1V16_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1274867.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            17775..19337
                     /locus_tag="L1V16_000503"
     CDS             17775..19337
                     /locus_tag="L1V16_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1274868.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            19330..20463
                     /locus_tag="L1V16_000504"
     CDS             19330..20463
                     /locus_tag="L1V16_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1274869.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            20463..21419
                     /locus_tag="L1V16_000505"
     CDS             20463..21419
                     /locus_tag="L1V16_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1274870.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            21518..22684
                     /gene="deoB"
                     /locus_tag="L1V16_000506"
     CDS             21518..22684
                     /gene="deoB"
                     /locus_tag="L1V16_000506"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBN1274871.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            22708..23526
                     /locus_tag="L1V16_000507"
     CDS             22708..23526
                     /locus_tag="L1V16_000507"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBN1274872.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            23543..24250
                     /gene="deoD"
                     /locus_tag="L1V16_000508"
     CDS             23543..24250
                     /gene="deoD"
                     /locus_tag="L1V16_000508"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBN1274873.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(24548..25234)
                     /gene="gpmA"
                     /locus_tag="L1V16_000509"
     CDS             complement(24548..25234)
                     /gene="gpmA"
                     /locus_tag="L1V16_000509"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBN1274874.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(25406..25987)
                     /locus_tag="L1V16_000510"
     CDS             complement(25406..25987)
                     /locus_tag="L1V16_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1274875.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(26120..26803)
                     /gene="rpiA"
                     /locus_tag="L1V16_000511"
     CDS             complement(26120..26803)
                     /gene="rpiA"
                     /locus_tag="L1V16_000511"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBN1274876.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            27122..27535
                     /gene="rpsL"
                     /locus_tag="L1V16_000512"
     CDS             27122..27535
                     /gene="rpsL"
                     /locus_tag="L1V16_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBN1274877.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            27619..28089
                     /gene="rpsG"
                     /locus_tag="L1V16_000513"
     CDS             27619..28089
                     /gene="rpsG"
                     /locus_tag="L1V16_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBN1274878.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            28183..30270
                     /gene="fusA"
                     /locus_tag="L1V16_000514"
     CDS             28183..30270
                     /gene="fusA"
                     /locus_tag="L1V16_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBN1274879.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            30442..31629
                     /gene="tuf"
                     /locus_tag="L1V16_000515"
     CDS             30442..31629
                     /gene="tuf"
                     /locus_tag="L1V16_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBN1274880.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            32036..32332
                     /gene="rpsJ"
                     /locus_tag="L1V16_000516"
     CDS             32036..32332
                     /gene="rpsJ"
                     /locus_tag="L1V16_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBN1274881.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL"
     gene            32363..32992
                     /gene="rplC"
                     /locus_tag="L1V16_000517"
     CDS             32363..32992
                     /gene="rplC"
                     /locus_tag="L1V16_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBN1274882.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            33020..33643
                     /gene="rplD"
                     /locus_tag="L1V16_000518"
     CDS             33020..33643
                     /gene="rplD"
                     /locus_tag="L1V16_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBN1274883.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            33643..33933
                     /gene="rplW"
                     /locus_tag="L1V16_000519"
     CDS             33643..33933
                     /gene="rplW"
                     /locus_tag="L1V16_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBN1274884.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            33972..34805
                     /gene="rplB"
                     /locus_tag="L1V16_000520"
     CDS             33972..34805
                     /gene="rplB"
                     /locus_tag="L1V16_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBN1274885.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            34848..35126
                     /gene="rpsS"
                     /locus_tag="L1V16_000521"
     CDS             34848..35126
                     /gene="rpsS"
                     /locus_tag="L1V16_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBN1274886.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            35149..35496
                     /gene="rplV"
                     /locus_tag="L1V16_000522"
     CDS             35149..35496
                     /gene="rplV"
                     /locus_tag="L1V16_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBN1274887.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            35510..36166
                     /gene="rpsC"
                     /locus_tag="L1V16_000523"
     CDS             35510..36166
                     /gene="rpsC"
                     /locus_tag="L1V16_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBN1274888.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            36169..36603
                     /gene="rplP"
                     /locus_tag="L1V16_000524"
     CDS             36169..36603
                     /gene="rplP"
                     /locus_tag="L1V16_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBN1274889.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            36593..36781
                     /gene="rpmC"
                     /locus_tag="L1V16_000525"
     CDS             36593..36781
                     /gene="rpmC"
                     /locus_tag="L1V16_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBN1274890.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            36806..37072
                     /gene="rpsQ"
                     /locus_tag="L1V16_000526"
     CDS             36806..37072
                     /gene="rpsQ"
                     /locus_tag="L1V16_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBN1274891.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            37130..37498
                     /gene="rplN"
                     /locus_tag="L1V16_000527"
     CDS             37130..37498
                     /gene="rplN"
                     /locus_tag="L1V16_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBN1274892.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            37535..37843
                     /gene="rplX"
                     /locus_tag="L1V16_000528"
     CDS             37535..37843
                     /gene="rplX"
                     /locus_tag="L1V16_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBN1274893.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            37871..38410
                     /gene="rplE"
                     /locus_tag="L1V16_000529"
     CDS             37871..38410
                     /gene="rplE"
                     /locus_tag="L1V16_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBN1274894.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            38429..38614
                     /locus_tag="L1V16_000530"
     CDS             38429..38614
                     /locus_tag="L1V16_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBN1274895.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            38650..39048
                     /gene="rpsH"
                     /locus_tag="L1V16_000531"
     CDS             38650..39048
                     /gene="rpsH"
                     /locus_tag="L1V16_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBN1274896.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            39080..39616
                     /gene="rplF"
                     /locus_tag="L1V16_000532"
     CDS             39080..39616
                     /gene="rplF"
                     /locus_tag="L1V16_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBN1274897.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            39777..40133
                     /gene="rplR"
                     /locus_tag="L1V16_000533"
     CDS             39777..40133
                     /gene="rplR"
                     /locus_tag="L1V16_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBN1274898.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            40154..40654
                     /gene="rpsE"
                     /locus_tag="L1V16_000534"
     CDS             40154..40654
                     /gene="rpsE"
                     /locus_tag="L1V16_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBN1274899.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            40669..40848
                     /gene="rpmD"
                     /locus_tag="L1V16_000535"
     CDS             40669..40848
                     /gene="rpmD"
                     /locus_tag="L1V16_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBN1274900.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            40892..41332
                     /gene="rplO"
                     /locus_tag="L1V16_000536"
     CDS             40892..41332
                     /gene="rplO"
                     /locus_tag="L1V16_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBN1274901.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDILNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            41332..42627
                     /gene="secY"
                     /locus_tag="L1V16_000537"
     CDS             41332..42627
                     /gene="secY"
                     /locus_tag="L1V16_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBN1274902.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            42689..43336
                     /locus_tag="L1V16_000538"
     CDS             42689..43336
                     /locus_tag="L1V16_000538"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBN1274903.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            43527..43745
                     /gene="infA"
                     /locus_tag="L1V16_000539"
     CDS             43527..43745
                     /gene="infA"
                     /locus_tag="L1V16_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBN1274904.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            43778..43894
                     /gene="rpmJ"
                     /locus_tag="L1V16_000540"
     CDS             43778..43894
                     /gene="rpmJ"
                     /locus_tag="L1V16_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBN1274905.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            43912..44277
                     /gene="rpsM"
                     /locus_tag="L1V16_000541"
     CDS             43912..44277
                     /gene="rpsM"
                     /locus_tag="L1V16_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBN1274906.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            44305..44694
                     /gene="rpsK"
                     /locus_tag="L1V16_000542"
     CDS             44305..44694
                     /gene="rpsK"
                     /locus_tag="L1V16_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBN1274907.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            44774..45712
                     /locus_tag="L1V16_000543"
     CDS             44774..45712
                     /locus_tag="L1V16_000543"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBN1274908.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            45740..46120
                     /gene="rplQ"
                     /locus_tag="L1V16_000544"
     CDS             45740..46120
                     /gene="rplQ"
                     /locus_tag="L1V16_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBN1274909.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            46392..47231
                     /locus_tag="L1V16_000545"
     CDS             46392..47231
                     /locus_tag="L1V16_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBN1274910.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            47207..48076
                     /locus_tag="L1V16_000546"
     CDS             47207..48076
                     /locus_tag="L1V16_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBN1274911.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            48066..48863
                     /locus_tag="L1V16_000547"
     CDS             48066..48863
                     /locus_tag="L1V16_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBN1274912.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            49066..49812
                     /gene="truA"
                     /locus_tag="L1V16_000548"
     CDS             49066..49812
                     /gene="truA"
                     /locus_tag="L1V16_000548"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBN1274913.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            50477..50714
                     /locus_tag="L1V16_000549"
                     /pseudo
     CDS             50477..50714
                     /locus_tag="L1V16_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(50858..51634)
                     /locus_tag="L1V16_000550"
     CDS             complement(50858..51634)
                     /locus_tag="L1V16_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBN1274914.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            51757..>51980
                     /locus_tag="L1V16_000551"
     CDS             51757..>51980
                     /locus_tag="L1V16_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBN1274915.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQN"
BASE COUNT        16531 a         9386 c        11260 g        14803 t
ORIGIN      
        1 aggaacttaa agtagaatgt aaatgaatag ttgtagtcag tcgattgtga tactagactc
       61 aaagttgcag gaataagttt ttcaatttgt gattggaaga taaaaaatga aaaagaaggg
      121 ctttttttta tactttgttg attgtagtgt ttattttccc tctgtttagc caagtaacat
      181 tttctatgac tcaaccagtt tcaagtgagg aacatgataa cctttttcgt gctacagaag
      241 agtttaagaa atatcaggaa aatattgttc cggagactcc attagctagt gagccaatta
      301 ctgatattga tggaaaccaa ataggatggt atatacagta cgaagttatg gtggtaaata
      361 atgactcaat agtaaaaaat acagtaggct tagagctaac accgattgaa aaggtgagtt
      421 cattgttaac gtatatttat actgatgaaa gtgacgagac tgagatcatt ttaacggatt
      481 actcaaaaat tgctactgat aaaaagtata tattgtggat gtagacacta gtgaaatact
      541 ttatgatata gaaattgatg aaaatttact agatgtagca caagaaatcg atcatcaaaa
      601 gcaggaagct attcgatatg ctggtagaaa agggaaaaga aaatatttat tacgtgaatg
      661 tagcaaaagt tagagaagat gaaaatgagt ggaaagaatt caagagtcgc tactcaatta
      721 actcgactcc gacatttaca gtttacagag aaggatcgat agaaaaaact gttttttgga
      781 ctaaagaaag tggaatgtct ttagctgaag tagaagagtt tttggattat gttagtatgc
      841 aacagtaagg gagttcttat tatgaaaaat tttgacacat attatgttat tgttttttcg
      901 atatctttgc tgttaatatt actaacttta atgcagtata aagagtatcc agagtatttt
      961 attttaactt ttgtatattt agtaagtagc tacacacttc tatataaatt cagaagttct
     1021 tctagagttt ctaaagtttg tttcttaatt agcttattga ttctataata tttttgattt
     1081 atataggaaa ttaaaaatat tatagaatca acactcagag aacgggttgg tttttaatag
     1141 atttaataag tactgataat gaaatttctc ctggttggga aaacgaagtt ggttaccctg
     1201 tagaagaatt ttttcaagat tactttgcgg agtatgccga taggataatg agagattacg
     1261 taacagataa aactcaagaa gtcatcaatc aatcccagtc attaaatgaa ttatctgata
     1321 aggcgaaaga agaagcagtt gccattattt cttcagggat tagtgactat attgatatga
     1381 gtggtgaaat caattatggc gataaagaca aaattgtacg catgataaaa gcttttatca
     1441 aaacttttga tgtgaaggca gatcttaagt ttaatgatac ttacctagta ggaaaattaa
     1501 ttaatatcct tgggacagag aaagatacgg aaacgtttat ttcctctttg tctatgttgt
     1561 ttacagataa gcatttttca actcagcttg gtggagagga actagtggaa atcttttaac
     1621 cattacgccc agcattaata aaagtatatc aaaaaagtac tcctgatgat ttttaagatt
     1681 ggtttgagaa ataatgtgaa aacactattt ttaatgttaa ttatagatag agatgaacgc
     1741 gtcatatggt taaaagaatg aaaaagtcaa agatacactg ctatatttca ctaaggatat
     1801 agcagtgtat ctttcatgtc gtttcactgg cagtttttta taaaaggagg tgtgcatttc
     1861 agttgctttt ctttggtagt tagttgaatc gtttaagaat taacggatgt ggcagacagg
     1921 tgctctgtcc aaaaaccagt aaaatctttg atggttccat ctttatttag ctgtgcctgt
     1981 tcaaatactg ttttgttttt accgaatgga tcaattgcaa taattgttcc gatccccgca
     2041 cgtttggcag caagtaatcc tgagtaagca tcttcgataa caagacaatc agccggagct
     2101 aagctcagtt tgtctgccgc tttaagaaaa atatccggtt gcggtttccc agggaaagag
     2161 ccgtcgtcat agacaatctt gtcccagtca aaccagcggg ctaaatcgaa aatatcaaaa
     2221 taaaaagcaa cattctcttt gacagtagcc gtggcaatcg ttaatggaat ctgttggtca
     2281 gtcagctggt caagagtcgc ttcaagccct tttgtcaact gaagctcgtt ttcattttgc
     2341 aagcaaagca tacgataata gctttctttt tcttctgaca atacggcgat ctcagaggcg
     2401 gtcaaatgct ctgaaatgaa atgtttcaaa atctccgtat tcgtccgacc atgaatattt
     2461 tttaaaatat cctcgtctga taaaccatct tttgtatgat catgtatcat atgcagccaa
     2521 gcagcttcat gcagatgaga gtccaaaaac attgttccgt tgaaatcaaa tataatccct
     2581 ttcatagtta cgctcctata gtggtatttt cggttgaatc agcaatttgc agatcgacat
     2641 attgtgcata gtgctcttga acctcccgcg agatctggcg atccgtaatg agcagatcga
     2701 aatcatgcaa attataaaac acataaaaat catctcgatt gaatttttta ttatcaacga
     2761 gtagatattt cttacgggaa ttatttagag cgatctgctg tgcttctcct tcttcggtac
     2821 tgtaagtaga gatcgcttcg ttgtgaacgc catttgaact gataaatgct tttgtaaact
     2881 ttagtcttct taaattgtcg ttggtgatcg gtccgacaaa tgcgccggta tttttccgga
     2941 aatcaccgcc aatcagtaga atttctggtc catctgcttg agcaagaata tcaaaaactg
     3001 gataattatt tgtaatgatc cgaattttct tgttcagtaa atgcgtcgcc aatagttcga
     3061 ttgttgtacc tggtcctaag aaaatcgttt ctccctcgtg aatcaaggag gctgctgtgg
     3121 cagcaatttc ttttttttct tgaatctgca gagtggcttt ttcagtgtga gaaagttctt
     3181 gatctaaagt gtaggaaaga ctttgagccc ctccatggac acgcagcagc ttgcccgatt
     3241 tttctaattc atctaaatct ctgcgaacgg tcatatcaga aacatctaat tgattgatga
     3301 tttcattaac ggtaaggatt ccttttttat tgaccatttc tacgatagta agcaatcttt
     3361 cttttttcaa cattgtcttc acctctaatt taaggataat ctatcatata aacggacaac
     3421 agtcaatcta attcgaacaa aagtaaacat ttagggtggt ttttatgttt gttacaatag
     3481 attttattgc tgttttctgg tttttatgat tatttgtgtt tgtttttgtt gacaaatgtt
     3541 ttggatgcgt ttacaatgca atcagttaga aagagcgaaa actgattata gatttgagga
     3601 gagatgtaca tgcttaaatt accagaagat tttatttttg gcggagccac agcagcctat
     3661 caggttgaag gagccactaa ggaaggtggc aaaggcgctg ttgcttggga tgacttttta
     3721 gaggaacaag ggcgattcag tcccgatccg gcaagtgatt tttatcatca atatgcaaag
     3781 gacattgaat tgtgtgaacg ttttggtgta aatggtctaa gattatccat tgcttggagc
     3841 cgcatttttc ctgatggagc tgggaaacca aatccagaag gaatcgcttt ttatcatcgt
     3901 gtgttcgaag aatgtaagaa aagaaacgta acgccgtttg tgacgttgca tcattttgat
     3961 acccctaaac gtttgtttga ccatggagat tttttgaatc gagaaacaat agaagcattt
     4021 gtttcctatg ccattttttg ttttcatgaa ttcaaagaag tcaaggtgtg gagtaccttt
     4081 aatgaaatct atccagttgc aaccaatcaa tatttgttag gtgttttccc accaggaatc
     4141 aaatatgatt ttacaaagat cgtcgcctgt cttcataata tgatggttgc tcatgcccgt
     4201 gtagtgaact atttcaaaga aaacgaactt ccgggtgaaa ttggtgtagt tcactcatta
     4261 gagacgaaat atgcggcaac agacgcgccg gaagataagc atgctgcctt tttagacgat
     4321 gcattgtcga tccgtttctt attagatgct acctatttag gctattattc aactgaaacc
     4381 ttgactgctc ttgatgagat atgtgaagca aatcaggcca gctatcattt tcctgaagaa
     4441 gatttcgttg aattgaaaaa agcatccacg cgtaatgact acttagggat caatcactac
     4501 caatgccatt ttgtcaaagc ttacgatgga gaaaatgcaa tccatcataa cggtacgggt
     4561 gaaaaaggga cctctgttta taaagtgaag ggaatcggag aacgtattta taaagaagga
     4621 attcctcgaa ctgattggga ctggctgatt tatccagaag gtctatatga cttgttgctg
     4681 cgaattaaaa gcgattaccc acattacaac aaaatctata tcactgagaa cgggatgggg
     4741 tataaagatc agtttgaaga tggcattatt atggatcagc cgagaatcga ctatttgaga
     4801 gtctatttgg aatccttaag caaggcgata acagccgggg taaatgtgaa ggggtatttt
     4861 ttgtggtcgc ttatggatct tttctcatgg acaaatgggt ataacaaaag gtatggcttg
     4921 ttttatgttg attttgaaac ccagaagcgt tacccaaaag aatcagctta ctggtacaag
     4981 ttggtcagtg aaaccaaaac gattatttaa taagtgataa tggaggaaga aaagatgaat
     5041 aaagaggaat tacaaatgct tggttttgag atcgttgcat attcaggcga cgctcgcagt
     5101 acattattga aattattgaa agaagtaaga caaggaaact ttgaacatgt tgattcggcg
     5161 ttgaaagaag ccgacgaaaa tttaaccctt gcacataatt cgcaaacaaa aattttagcg
     5221 gaagaagcat ctgggaaaga gatggagatg ggattcattt ttatccatgg gcaggatcat
     5281 ttaatgacca ctttattgct gagagatctg attcaagact ttattgtact gtacagacag
     5341 aatcaaggat aggagaagaa cgctatggat ggaatcatta aacaaatcga aaaagggaaa
     5401 ccattttttg aaaaaatctc acgtaatagt tatttaggag ccgttcgtga cggattttta
     5461 acagcgatgc cagctatttt attttcaagc attttcattt tgattgctgc ggttcctgag
     5521 atttttggtt accaatggcc tgaatctgtc tccacatggc tatggaaagt ctataattat
     5581 tcgatgggtg ttgtagggtt actcgtttca gcaaccactg ctcgctgctt ggctgattcg
     5641 atgaatcgtc gcttaccgaa aaacaaagta atcaacacca cctctgtgat gctggcctct
     5701 gtggtaagtt tcctgttgtt aagcgtctct ccgattgaag gtggattttc aacggaatat
     5761 atggggacaa agggactact ggcttccttt gtcgctgcat ttttaacagt taatttatat
     5821 aagttttgtg tgctgaaaga tattaccatt aaaatgccta aagaagttcc tggaacgatt
     5881 tcgcaaacct tccgagatat ttttcctttc tctttttcag tatttgcggc cgttttaatt
     5941 gatttaggca ttcgacaaat cttccaaatc tcatttgcag aagcaatcat tacggtgctg
     6001 cagccgctat ttacagcagc tgacgggtac ttaggaatcg ctattatctg gggagcgatg
     6061 gcgctgtttt ggtttgtcgg tgttcatgga ccgtcgatcg tggagccggc aattgcggca
     6121 attatctatg ccaatgtgga aaccaatctg caattgttca attccggtga acaagcttct
     6181 aaagtactga cggtgggttt agggaatttt gtaggaacta tgggaggaac tggggcaaca
     6241 ttggttgttc cttttatctt cctactcttt gctaagtcta agcagttgaa ggcagttggg
     6301 aaagcttcct ttattccagt aagtttcgct gtcaacgaac cattgctatt tgcggcaccc
     6361 atgattttga acccttattt ttttattcca tttttgttaa cacctgttgt aaacgtttgc
     6421 ctgttcaagt tttttgtcga tgtattgggc atgaacagct ttatgtacgt tttgccttgg
     6481 gcaactccag caccgatcgg tttggttcta ggaacgggca tgggtatctt agcttttgtt
     6541 ctagcagcgg ttctaatcgt cgttgacttc ctgatctatc taccattttg caaagcatac
     6601 gatgctgtct tagtagagaa agaagcacaa aaagcagagg tgatcgcaac cgaggaaggt
     6661 gcttctgccg atgtacgtga ggaagtacct gtggcagcga gtcaagttat cagcgatgca
     6721 aataaagaaa tcaatgtgtt ggtactttgt gctggcgcag ggacaagtgc gatgttagct
     6781 aatgctttaa aaaaaggtgc atctgaatcg aaagcaccga tcagtgcaat ggcgggtgct
     6841 tatggttctc attacgaaat gctgcaggat tttgatatgg tggtcttagc accgcaagtc
     6901 aattcttact atgatgatat caaagaagac accgatcgct taggaatcaa gctggttgcg
     6961 acaaaaggag cagaatatat cggattaacg agagatcctg aaaaagctgt tcagtttatt
     7021 ctgaaccaat ttcaataaag gaggagccat aatgaaaatg ggaatttggt tgcgtaaagc
     7081 tgttttattt gcagctgtgt taggggcttt gggggctgtt tcaaaaactg ttgaagcatc
     7141 tgccagcgaa tttattcgcg gagcagatat ttcgatcctg tcagatatgg aaaaatctgg
     7201 tgcaaaatat tatgaagacg atatttcaaa agatgcctta gagattttaa aaaataatgg
     7261 tgtcaactat gttcgactgc gtttgtggca ggatccttat aatagtaatg gagaaagtta
     7321 tggagcaggg acaaatgatc tggaaacgac gattgacctt gcaaaacgag caaaaaatct
     7381 gggacttaag gtgctgctgg attttcacta cagtgatttt tgggttgatc ctgggaaaca
     7441 gaatcttcct aaagcatggc aaggtctgac ctttgaagaa atgaatacgg cattgtacga
     7501 ctatacaaag aacgttctgt cggaaatgaa gcagctggac gtttatcctg atatggttca
     7561 gatcggcaat gaactgaata gcggaatgct ctggccttat ggcaagtctt ggggagaagg
     7621 cgggggagaa tttgatcgat tggctgcttt tttgaagtct ggtatccaag ctgttcgaga
     7681 cactcaacct aaaacaactc cagtaatgct ccacttagct gatggtggcg atacaggagc
     7741 atttacttgg tggtttgatg aaatcacgag tcgaggtgtg tcatttgatt taattggagt
     7801 gtcgtattat ccgtattggc acggttcaat gaatgaactt caaaccaata tgaatgcgat
     7861 cagccaacgg tatggtaaag aagtgatcgt agttgaaaca gcttatgggc atacaacagc
     7921 gaatgccgat actatgccaa atgcttttgg tgaagccgaa gcagctgcgg ggggatatga
     7981 accaacaccg acaggacaag cagagtattt gctggatctt gccgatcgga ttcaggcagt
     8041 accgaataat cgcggggcgg gcttcttcta ttgggaacct ctttggtaca acggaaatgt
     8101 gagttgggca acacaagcag gtatgaatta tctcagtgtt caatccacta tgggaaacga
     8161 atgggacaac caagcgatgt ttgattttgc tggaaacgcc ttgccaagct tgcgtgcgtt
     8221 taaacaagca ggggcgcaaa taaatctagt taaaaatgca agtttcgaaa gcgatggacc
     8281 aacgaccagt ccttccaatt ggcaaacctg gtttcaacaa ggaaccgcta agggtacgat
     8341 caaaacggaa gcgggcactt tttttgggga ctacaaacta actttttggc aggatcaagc
     8401 atacgaggca tcagcttatc aaaatgttag tggcataagc aaaggaactt acacattgag
     8461 tgcctatgta atgtctgggg gagagtttga tactaatcag ttatatatca aaaattatgg
     8521 tggagcggaa ctaaatactg cggttgttaa aacaagtgaa tggacaaaaa ttacaatcaa
     8581 agacattcca attacaacag gtgtttgtga aattggggtt tatagcaagg cttcaggaaa
     8641 tgcttggacg aacgttgatt ttgtttcatt ggtgaaacaa tagactgcgg atcgtttcga
     8701 ttcaagatcg gaggttccct tcagccacat cgttagcgta gaaggcagga atcgaacctg
     8761 cacctcgcct ttgccaaaaa taaccagaaa cgatttccag tcatttttac caaaacgagt
     8821 aaagcaccag acttcatcta cactttgtat tatgctaaag agagttcaac gatttcgtaa
     8881 gaagcaatga aaaaattgca aaaagttgtg cagataacat aaagtttgtt taagaaaggg
     8941 taaccttaga attccgtcgt gaatatgatt tgagcactta gatggataga aaaaagttct
     9001 cggaaaacag ttcgtttttc gagaacttct ttttatgata agaatgaaac aaattaactt
     9061 atattatagt ctcttttggt agggaaccat cttattttta atgaaaatca agcattttag
     9121 ctattgaaga atgttgattt atagggattc cccctccata ttatgttggc tctttattcc
     9181 cactccactg ttgctggtgg tttagaagtg atgtcataca cgatacggtt gacgtgggct
     9241 acttcgttta cgatacgtac agagattttt tgcaagactt cccatgggat acgggcaaag
     9301 tcagcggtca ttccgtcgat tgaagttaca gcacggatac cgactgtgta gtcgtaagta
     9361 cgtccgtcac ccataacacc gacagagcgg atccctggaa gaacagtgaa atattgccag
     9421 atatcacggt caagtccagc agctgcgatt tcttcacgca agatagcatc agattcgcgt
     9481 acgatttcta gcttgtcttc agtgatttcg ccaagaacac gaataccaag accaggacca
     9541 gggaatggct gacgccaaac gattgaatca ggcatgccta actgagtccc taattcacgg
     9601 acttcgtctt tgaataatgt gtttaatggt tcgatcaatt caaattgcat atcttctggc
     9661 agtccaccta cattatggtg agatttgatc gtctgtgctg tttctgtacc agattcgata
     9721 acgtcagtat acaacgttcc ttgtgctagg aaagagacgc cttcttcacc agcaagtttt
     9781 gttgcttcgt catcaaaaac atatacgaat tcattcccaa tgattttacg tttttgttct
     9841 gggtcagata cacctttcaa cttgtctaag aagcgatctc ttgcattgac tttgatgatg
     9901 ttcaagccga attttccgcc tagactttcc attacttgtt ccgcttcgcc tttgcgtagc
     9961 agaccgtggt caacaaagat agatgtcaat tggtcaccga tcgctttttg taaaagaacc
    10021 ccaacgacac tagaatcaac gccacctgaa agaccaagca agactttttt gtcaccaact
    10081 tgttcacgga ttttttctac ttgcatatcg ataaagttat ccattgtcca gttaccttca
    10141 cagtgacaaa catcaaaggc aaagtggcgc agcaattcga ttccgtattc ggaatgacgt
    10201 acttctgcat ggaattggat accataaaaa ttacgtgttg tgtcttggat agaagcaatc
    10261 ggacaatctt tgcttgttcc gactgtttca aagccttcag gaactttagt taccaagtca
    10321 ccatggctca tccatactgt ttgttgtttt ggtgtttctt taaacaagac agcttgatcg
    10381 cttgttactt ctaacaaggc tttcccatat tcgcggtttt tagcaggctc tacggaaccg
    10441 ccaagtttgt acgtgatcaa ttgcatacca tagcaaatcc ctaatacagg aatacctaaa
    10501 ttgaagatct caggatcgat cccaaatgca ttctcatcat atacactgtt tggtccgcca
    10561 gaaagaatga ttccctttgg attcatcgct tttacttctt ctgcagtaat gcggtggctc
    10621 aataattcgg aaaagactcc aagatcacga atacgtcttg tgatcaattg gttatactga
    10681 ctaccgtagt ctaatacgat aatcttttca acgttcgtca tatcggcaac gtttgtcaaa
    10741 tttattaccc ctatcccttt aaattttatc tcaaaatagt caaactattt taaaatgcta
    10801 atattttcgc atgaaaatcg aatcgatgat atgattttca gttttatgga gaattatatc
    10861 ggctcttcct cgtgtaggca agatatattc ctgtaaattt ttcaaattca catttttcca
    10921 tacatctttt gccattttaa aggcttcttc acgatctccg atagcaaaac gataataata
    10981 attctctgga ttttggaaag ccgtatccag taacgcacca aaacgatcca aataccattt
    11041 ttcgatcagc acgggatcgg catcgacata gacagaaaaa tcaaaaaagt cgctgacgta
    11101 gatttgctga ttcgcaggta attgaagcgt attgatcccc tcaacgatca agatatcagg
    11161 ctgctggatc aattcgtact tgtctggaat gatatcatac acatcatgtg agtaaacagg
    11221 tacttttatc tcttcctgac cagattttac acggttcaag aaatcgatca gcatctccat
    11281 atcataactt tcaggaaatc ctttacggtc catgattcca cgctctttta atatacgatt
    11341 tggataaaga aatccgtcag tcgtgatcag ctgaacgttt cttcgtttga aggtacgaga
    11401 caaaatcgtc tgcagcagtc tggctgttgt actttttcca acggctacac ttccggcgat
    11461 cccgataata aaaggcggta cttctacgta tttatgaaga aataaacctt tactcaagaa
    11521 caaagattca aattctttca tataaagata aatcagatga gcaagaggta catagatatc
    11581 tcgaacatcc tgcatggaaa tgcggtcatt caaacttttg atattatcta gttcatcttg
    11641 tgtcaaaggt gcttgcccat tacgataaaa ttctcgccat tcttctcttg ccacacggta
    11701 gtagttcatt ggatcattca tattagcctc ctgcgttctc ccatcaatgg aactatttta
    11761 acacaaaata aacgcaaacc ccaccactta agagagattg ccgatctttt tgtataatct
    11821 ttataataga aagaaacgga gtcttattct tgacttgcgc acggatacat aaaaggatag
    11881 actgttgtca tgaaagaaat gagaaggatg gaagacatga caaatcatta ctattctgaa
    11941 cgcccagata cggcgcacga ttttgaacaa tgggcttttg agttaaaagg cagaaccttt
    12001 caatttgtaa cagattctgg tgtattttca cgtgaaacag tggattatgg ttcacgtgtc
    12061 ctgattgatg ctttcgattg ggaagagtta cctgatgaag gaaagatctt agatgtggga
    12121 tgcgggtatg gaccgattgg gttagctttg gcatttgcga cacagcggtt tgttgaaatg
    12181 gtcgacatta atgaacgagc ggtaagtcta gcgcaaggaa acgcaaagcg taaccaaatc
    12241 gaacatgttg atatccatca atcgaatatc tatgaagcag ttcatgaaga aacctatgca
    12301 gctatcgtaa gcaatccgcc gatccgtgct ggaaaaaaag ttgtacatga aattttgaca
    12361 ggcgcatatc ctcggttgaa gaagggcggt acactgacaa ttgtgatcca gaagaaacaa
    12421 ggagcgccga gtgcgcaaaa gaaaatggaa gaaacatttg gtaatgcaga aatcgtcaca
    12481 aaagataaag gatattatat catcaaaagt gtgaaagaat aactagctga aaaatagtgg
    12541 agcgacgaaa gagtggaact gggcgtgcat gtacgggtac gtatcagttc tttttttgtt
    12601 gagaagtttt taaaaacaaa gaactatttt ttcttcaaaa agaaatagta ggaacagagt
    12661 cgttgttttt tacgataaaa taaataagat acagaacttg tatagaaggc tgccaagtcg
    12721 gtagataaag gaggttttta tcaaaaaaca tactttcctt ttttctctat tcttttcttg
    12781 ggggttttgg tacactgata gggaatttag atagaaggga gccaatagga tgaagctgac
    12841 catcagagat atcgcagaaa tggcaggcgt atcagtaaca actgtctcac agattttgaa
    12901 taacaaagga agcagattta gtgataagac aagaaaaaaa gtgttgtcga tcgtgaatga
    12961 acatcattat aagcccgatt atttcgcttc aaatgtgatc aatcgacatt caaagaccat
    13021 cggaatgatc gtccctgatg tcactgattt cttcttctcc aaactgatcg aaggtgtaga
    13081 gagctatttg aatcctttgg gctatgtgat catgttatgc aattctcgtc atagccaaga
    13141 aaatgagatc aagtatttac aagagctttc ccaccgctca gtggacggaa tcttgctggc
    13201 cacaccaaat attttacctg agaaatatgc attagacagc ggtttttatc aaaaaatgcc
    13261 aatcatttta atcgatcgcg gattgaatcg tcgggataac ggacggctta tcgtaaagga
    13321 atatgagggc gcctatcaag ctgtttcgct gtttattgaa aatggccata cgaagatcgg
    13381 catgctgaag gaaaccactg gatactatca attagaagaa cgtttcaacg gatatcgtca
    13441 tgcgctgaaa gatcatggcc tgccttttaa tgggaaattt gttgaacatg gagagttgac
    13501 tgtccaaggt ggatatactg catcaaaaaa attactcaaa cataaagata tcacggctat
    13561 tttttgcggg aatgatgcca tggcgatcgg atgctatcag gcgatcgatg aattgggcaa
    13621 aaaaatccca gaagatatct cagtcatagg attcgatgga ttaaagctgt cagaatacat
    13681 gattccgcaa ttgacgacag tgcagcagcc aagttttgat attggatttt atgctgcacg
    13741 tttcctgatc gatacgatcg aatttcctca aagaaaagtt ccgaacaaag tgttcgaaac
    13801 aaaattaatt attcgtgaga gcgtaaaagt attgacaaag ggctaactcg gcggtatatt
    13861 gcttatgtaa gcatttacaa aggctagtta gtgctttttt tatttttagt aaaccagttt
    13921 actaaagtgg tttacctttc ctaaaaataa tgtataatac cgaatgaaga caaggaggat
    13981 caggcaatgc gaatggtgga tctgattgaa aaaaagaggg atggaaacga gctgtcgaaa
    14041 gaggaaatcg agtacatcgt cacgaactat acgaatggaa agattccaga ttatcaagtc
    14101 agtgcattat tgatggcaat tttttatcaa gacatgacaa atgaagaaat cacgaactta
    14161 acattggcga ttgctaattc tggtgatgtc atcgatttga gttctcttga aggaataaag
    14221 gtagataagc attcgacagg tggcgttggt gacacgacca cattgatttt agccccccta
    14281 gtagctagtg tcggagtgac agtggctaaa atgtctggac gcggtctagg ttacacaggt
    14341 ggtacactag acaagctaga agcaattccc ggatttcaga tcgagctttc ggatgaagaa
    14401 tttgtacgca ttgttaatga aagtaaagta gcggtaattg gtcaatcagg aaacttggca
    14461 ccggcggaca aaaaattgta tgccttgcgt gacgtcacag cgaccgttga ttctcttccg
    14521 ctgattgcca gttcgattat gagtaaaaaa atcgcggcag gagcagatgc aatcgttttg
    14581 gatgtgacca ctggagacgg tgctttcatg aagaacatcg aagatgcaag acgtctggca
    14641 aagaccatga cgagcattgg gaaactggct aaccgagaaa cagtggcggt tatctcagat
    14701 atgtcagaac ctcttggcga agctatcgga aatagtctag aagttgtcga ggcaatcgaa
    14761 acattacaag gaaatggtcc agaagatcta gtagaaatgt gctacgcctt aggaagccaa
    14821 atggttgttc ttgctggcaa agctaagaca accgatgaag caagaacgtt gcttcaagaa
    14881 gctctggaat caggtaaagc gttagcaaaa ttcaaagaaa tgatccaaaa tcaaggggga
    14941 gacccagcga tcgtggaaca tccagaacga attttgactg cacgctacac aatggagctt
    15001 cctgctaaac aaagcggagt tgtgtcaaaa atcgtggcaa atgaattagg aattgctgca
    15061 atgatgctag gtgctgggcg taaaaccaaa gaagaagata ttgatcacgc tgttggattg
    15121 aaactgcata aaaaaattgg tgacactgtg acaaaaggtg agtcactatt gacgatctat
    15181 agtaacgacg aagaaatcac ttctgtcatt gaattattat ataaaaatat tgaaattggt
    15241 gaatcggcaa tgaagccaac gttgattcat gacatcatca cagaataaag gaaaaaagcg
    15301 gactttaccg ttttaaagaa aaggggaaaa gaaatggaac taaaccgaat gatcgaccat
    15361 actattttga aagcagacgc atctaaagaa gctgtgatgc aaattatcga agaagcaaaa
    15421 aaataccatt tttattctgt ctgcatcaat ccagcatggg ttgcgctagc gaaagaacaa
    15481 ttacaaggtg agccagtagc cgtatgtaca gtaatcgggt ttcctctagg agcaaacaca
    15541 cccgagacaa aagcatttga aacaacagat gccatcaata acggtgcaga tgaagtcgat
    15601 atggtcatca atatcggtgc tttgaaatca aaggatgatc aacaagtcca aaaagatatc
    15661 gaagcagttg ttgaagcagc aaaagatcgt gcgcttgtca aagttattat tgaaacatcg
    15721 ttattagata gagaagaaat catccgagct tgcgaaatag caaaagctgc aggcgctgat
    15781 tttgtcaaaa catcaactgg tttctcaaca ggcggagcaa aggtagagga tgtccgtttg
    15841 atgcgtgaaa ctgtaggacc agaaatgggt gtcaaagctt ccggcggtat ccataacgaa
    15901 gaagaagcaa tggcaatgat cgaagctggt gctacaagaa tcggaacaag cgcaggagta
    15961 gcaatcgtat ctggttcaac tggtgaaggc tattaatttt ttcaaaggag aagctcatgg
    16021 cagaactcaa acaagaatgg atcaacacag ctattgaagc gttagataaa gcctatgttc
    16081 cttattccca ttttccggta ggcgcttgtc tcgtaacgga atcaggcaag atttatcaag
    16141 gcatcaacat tgagaatgca tcatttggat taacgaattg tgccgagcgc acagcttttt
    16201 tcaaagcagt atctgaagga gaaaaaacat ttacgcatct agtcgtagcg gggcacaccc
    16261 ccgatcctat ctctccttgt ggtgcatgtc gacaagtaat ggcagaattc tgttcccctg
    16321 atatgccggt tacgctagta ggagacaatg gtgtgacgaa ggcaacgacc gttcgtgcac
    16381 tgctgcctta tgcatttact gaaaaagatc tataactcat gttcattcag tcagctgact
    16441 gttgaaaaat aaaacaatta ttttaggagg ctttacagaa atgaaaaaag caaaattatt
    16501 tggtttaggt gctgtcgcac tagcagcagg gttattttta ggtgcatgcg gcaacaacgg
    16561 ctctactgat tcatccggtg gcaaaagctc atcagacaca acaactgcag cattgatcac
    16621 agacacaggt ggtgtagacg accgttcatt caaccagtca gcttgggaag gactagaaaa
    16681 atgggggaaa gatcaaggac tttcacgagg aaatgatggc ttccaatatt tccaatcttc
    16741 aaatgaatca gattacatcc caaatattga ccaagcattg aatgctggat tcaaaacgat
    16801 ttttggtatt ggttataaac taaaaccagc gatccaagaa caagcaacaa acaatacagg
    16861 tacgaacttt gttattatcg atgatgtcat cgatggatta gataacgttg tatctgcaac
    16921 tttcaaagac aacgaagctt cttatcttgc aggtgttgca gcagcttata cgactgaaac
    16981 aaacgtagtc ggctttatcg gcggtgtaaa aggtgaagta atcgatcgtt ttgatgctgg
    17041 attcaaagcc ggtgttgatg caggtgcgaa agaattagga aaagaaatca aagtattgaa
    17101 tcaatatgct ggtgacttct ctgctccaga taaaggacgt tcaattgctc aaggtatgta
    17161 tgcacaaaac gcagatatca tcttccatgc ttcaggcggt acaggtaacg gtgtattcca
    17221 agaagcaaaa tcattgaacg aatcaggcga caaaaaagtt tgggttatcg gtgttgaccg
    17281 cgaccaatca gacgaaggcg aatacacatt aaacggcgaa aagaaaaact tcacattgac
    17341 atctacactg aaagcagttg gaacagtagt agaagatttg gcacaaaaat cagcggacgg
    17401 taaattccct ggcggcgaac acactgttta tggattgaaa gaagacggtg ttggtctaac
    17461 agaaggacaa ctttctgacg aagcgaaaaa agcagttgat gaagcaaaag aaaaaatcat
    17521 ttcaggtgac gtaaaagttc cagaaactcc tgaagaaaac taaaaccatt tctatagcct
    17581 tgttagacac atgtttgaca aggctatggt ttgattagaa caagaattgt tcatttatcc
    17641 aagctgcctt gtgacagttt ggataaggga acaactccct gaagtaatgt ttgtttcaaa
    17701 agaagaacgc tcactaagcg tgaatcttag tcaatcgttg ccctagatag aaatcgttag
    17761 gatgtgaaaa aaaggtggtt caagaaaata ttgtcataga aatgcagaat attaccaaag
    17821 aatttggaac attcaaggca aatgacaaca tcaatttaca agtaaaggca ggagaaattc
    17881 atgcgttgct tggagaaaac ggtgctggca aatctacatt gatgaacgtg ctttccggat
    17941 tattagagcc gacatcaggg aaaattttga tgcgtgggaa agaagtaaag atcacaagtc
    18001 cgaccaaagc caaccaatta gggattggga tggtccatca gcactttatg cttgttgatg
    18061 cctttactgt aacagaaaac atcgtgttgg gaagcgagcc tagtcgcgca gggatgcttg
    18121 accataaaaa agcacgaaaa gagatccaaa aagtttctga acagtatgga ttgtcagtca
    18181 acccagatgc ttacgttcgt gatatttcag ttggaatgga acaacgggta gaaattttaa
    18241 aaacacttta ccgaggagca gatgtactga tttttgatga gccgacagct gtattgaccc
    18301 ctcaagaaat tgatgaatta atcgtgatca tgaaggaatt agtcaaagaa ggcaagtcga
    18361 tcattttgat tacgcataag ttagatgaaa tcaaagcagt agctgaccgc tgtacagtta
    18421 tccgccgtgg aaaaggaatc ggtacagtca acgttaaaga cgtaacctca caacaattag
    18481 ccgatatgat ggttggaaga acggtttcat tcaaaacgat gaaaaaagaa gcgaagcctc
    18541 aagaagtcgt tttgtctatt gaaaatctag tggtgaaaga aaatcgtgga ttagaagccg
    18601 tgaaaaactt gaacttagag gttcgtgctg gcgaagtact tggtatcgct ggaatcgatg
    18661 gaaacgggca gtcggagttg atccaagctt tgactggttt gcgaaaggca gaaagcggac
    18721 atatcaagct aaaaggggaa gacatcacta ataaaaaacc ccgaaaaatc actgaacatg
    18781 gtgtaggaca cgtgccagaa gaccgtcata aatacgggtt agtcctagat atgacattat
    18841 ctgaaaatat cgcactacaa acctatcatc aaaaacctta cagtaaaaac ggcatgctga
    18901 attattcagt aatgaatgaa catgccagag aattgatcga agaatatgat gttcgaacaa
    18961 cgaatgaact tgttcccgca aaagctttat caggcggaaa tcagcaaaaa gcaattatcg
    19021 ctcgtgaagt cgaccgagat cctgatctgt tgattgttgc aaatccaact cgtggactgg
    19081 atgtaggtgc gatcgaattt attcataaac gtctgatcga acaaagggac aaatacaaag
    19141 cagtgttact gatcagtttc gaattagaag aaattttaaa tgtttcggat cgtattgctg
    19201 ttatccatga aggagaaatt gtcggtatcg ttgatccgaa agaaacatct gaaaatgaat
    19261 taggtctatt gatggcgggc tataccttag aagaagcacg aaaagagtta gaaaaggggg
    19321 ctggcgcaca tgaatgatcg cagcgaaaaa ttccgtaatt tattagtgcc tgtactttca
    19381 gttgttttag gattgatctt aggcgcgata ttgatggctg cttttggttt tcagcccatc
    19441 caaggttatt cttctatgct agatgcagcc cttggttcgc aaagagggat aggtgaaacg
    19501 ttaaggcaag caacgccgtt gatttttaca gcattaggtt tttctgtagc taactcagct
    19561 gggtttttca atattgggct ttctggacaa gcactttgcg ggtggatcgt cagtgtctgg
    19621 gtggcacttg cgtttccaga tctgccaaaa gttgttttgc ttccgttatg cgtgatctta
    19681 ggtgccttag ctggtgcgat ggcagcggct gttccaggtt tacttcgagc attttttgga
    19741 acaagtgaag tgatcgtaac aatcatgatg aactatatct tattatacgt aagcacattt
    19801 gctttacatg aagtgatgcc tgaaagctat cgctcaagtt tggactcttc caatatgatc
    19861 agtcaaaatg cctcactgcg gttaccatgg ttaacacaag cttttggcgg ctctcgcgta
    19921 aactcaggat tatttttagc aatcatcgcg cttattttcg tttggctgct gatgaagaaa
    19981 acgactttag gatttgaaat ccgttctgtt ggattgaatc cttttgcttc tgagtatgca
    20041 ggaatgagta gtaaacgtac gatcgttttg tcgatggtca tttctggcgc tttggcaggg
    20101 cttggcggtg tggttgaagg attaggaacg tatcaaaact tctttgttca aacgacttcg
    20161 ctatctattg gatttgacgg aatggctgtt tccttgcttg gttctggatc agcaatcggt
    20221 attcttttat cagcgatctt gttcagtatt ttgaagatcg gtggacttgg catgcagaca
    20281 ggagcaggtg ttccgtttga gatcgtcaat gtatcgattg ctttgattat cttctttgtc
    20341 gggatcaact tcctgattcg tttcgtcatg gctaaagtct tccaagggaa aaaacaagaa
    20401 gagatcgttg cgacaataga atcgaaacca acgaatcaaa accatgaagg gggcgaacta
    20461 taatgtcgac tatcgaatta attgccttga tccttacttc tacactggtt tattcaacac
    20521 cgctaattct aacgtcacta ggcggaactt tttctgaacg aagcgggatc gtaaacgtag
    20581 ggctagaggg aatcatggtc atgggtgctt ttagttccat cgttttcaac ttgacgatga
    20641 gtccatcact tggttctatg acaccatgga tcgctatttt agtgggtggc gtcgtaggta
    20701 tcctattttc tctgattcac gcagtagcaa cagtcagttt gcgtgctgac catattatca
    20761 gcgggacagt aattaatctg atggcacctg ctttaggtgt tttcttgatc aaagcatggt
    20821 atggtaaagg tcaaactgat aacatcacgc agaatctggg gtatttttct ttcccaggat
    20881 tagcagatat tccggtcatt ggaccaattt tctttaaaaa tacattctta cctgcttatt
    20941 gtgctatttt gattgctgtc ctagcttggg tgatcatctt caagacgaaa ttcggcttgc
    21001 gcctccgttc agttggtgaa aatcctcaag ctgccgacac attaggtatc aatgtatatg
    21061 ctatgcgtta ttcaggcgta ctgatttctg gcttgttagg cggtatgggc ggtgctgttt
    21121 ttgctcagtc gatttccggt aacttttcag ctggtacgat cgttggacaa gggttcatct
    21181 ccatggctgc tatgatcttt ggtaagtgga atcctttagg ggcaatgggt gcctcattgt
    21241 tctttggttt tgctcaaagc ttgagtatca ttggcgcaca attaccagtt atttcttcga
    21301 ttccgccagt attgctgcaa attgctccat atttgctgac aatcattgtg ctggttgttt
    21361 tcttagggaa agcttctggt ccaaaagcaa acgggaagaa ctatatcaaa tcaaaataat
    21421 cttttagcga ataaaaaggg tgggttacgg gaagtgtttt tcgtctcgcc ctttttgttt
    21481 taaaggcaat aaaaataaaa agaaagaagg aataatcatg tttaaacgcg tacatctgat
    21541 cgtcatggat tcagtaggaa ttggagaagc accagatgcc gataagttcg gtgatgttgg
    21601 ttctgataca ttaggacaca ttgcgaaaga agcaggattg aacgttccac atttagagca
    21661 gcttggttta ggaacgatcc gtcctcttga aggtgtggaa tcagtgaaag atcatcaagg
    21721 ctatgcgacg aaattagaag aagtttctgt agggaaagat acgatgacag gccactggga
    21781 aatcatggga ttgaatatca aaactccatt tcgtgtgttt cctaatggat tccctgatga
    21841 tctgatcaaa caaatcgaag aattttctgg ccgtaaagtc gtatgtaaca aaccttatag
    21901 cggaacagct gttattgacg attacggtga acaccaaatg aaaacaggcg atttaattgt
    21961 atatacttct gccgatcctg tccttcagat cgcggcacat gaagaaatca ttcctttaga
    22021 agaattatat cggatttgcc aattcgttcg tgatataaca aaagatgatc cgtatatgat
    22081 tggccgaatc attgcacgtc cgtacgtggg tgaaccagga gacttcacac gaacaagcaa
    22141 tcgccatgat tatgcgttga atccattcgg acacacagtc cttgattctt tgaaagaagc
    22201 aggaaaggac gtgattgctg ttggaaagat caacgatatt ttcaacggac aaggaatcac
    22261 tgaatctgtc cgcacgaaaa gcaatatgga tggcgttgac cagctgctga aagttatgaa
    22321 aaacgatttt tcaggaatca gctttaccaa tttagtagat tttgatgcat tatacggtca
    22381 tcgtcgggat gtagtcggct atgcgcatgc gattgaagaa tttgacttac gaattccaga
    22441 attgcttgaa gcgatggaag aagacgactt gctaatgatt acagccgatc acggaaacga
    22501 tccgacgttt actggtaccg atcatacgcg agaatatgta ccgttattgg tttacagtaa
    22561 aaaaatgaaa gaacaagggg cattgcctca aggatattat tcagatattt cagcaacgat
    22621 tgctgagaac tttagtgttt cttcgactga aaatggcgaa agcttcttga aattattaaa
    22681 ataatctttt taaataggag aaagcaaatg accaagttaa gcgagatgtt acaagaaacg
    22741 acccagttta tccttgataa aggagtaaaa gaaattgatt ttggtttgat tctaggttca
    22801 ggattaggtg aattagcaga tgaaatcgaa gatgctgtaa tgatttctta tgatgagatc
    22861 ccgttctttc ctgtttcgac agtagttggg catgcaggaa agctagttta tgggtctctg
    22921 gcaggcaaga aagtgttagc catgcaaggg agattccact actatgaagg tcattccatg
    22981 caaacagtga cctatccagt acgtgtgatg gccggactag gggcccattc agtcattgtg
    23041 actaatgcat gtggtggtgt caacgaatca tttgtaccag gagatttgat gctgattacc
    23101 gatcatatca attttactgg tgaaaatcct ttgatcggtc cgaatgaaga tgcaatgggc
    23161 cctagatttc cagatatgag tcaagcttat acgcctgact atcaagcaac agcaaaagca
    23221 gcagcagaaa aactaggttt ggatcttaaa gaaggcgtat atatgggcta ttctggacca
    23281 acttatgaaa cgcctgcgga gatccgaatg tctcggacaa taggagccga tgcagtaggg
    23341 atgtcgactg ttccagaagt catcgtagca gctcacagcg gattaaaagt gttaggaatc
    23401 tcttgtatta ccaacttagc agcaggtatg caagcgaatc tgagccatga agaagttgta
    23461 gaaacaactc agagagtcaa acaatctttt aaagcattgg ttaaagaaac attgacatta
    23521 ttgtaatagg aggaacaata aaatgagtgt gcatattgaa gcgaaagaag gcgagatcgc
    23581 cgataagatt ttacttccgg gagatccttt gcgagctaaa tatattgcgg agactttttt
    23641 ggaagatcca gtttgttaca atcaggtacg cggtatgtta ggctttaccg gcaaatataa
    23701 aggagaacgt atttctgttc aaggaacagg aatgggaatg ccatcagcca ccatctatgc
    23761 ccatgaattg atccagtcgt atggtgtaaa gaaattgatt cgagtaggta catgcggtgc
    23821 attgtcaaaa gacgtccatg ttcgtgattt agtactagca caaggtgcag cgaccagttc
    23881 ttcgatgatc gaaaaaaatt tccaagcctt tcattttcct ccaatcagtg atttcaatct
    23941 attactgaaa gcatatgaga tagctaaaga aaagggctat acggttcatg taggaaatgt
    24001 tctttcggaa gattctttct acaaagatga tttgacagag acgttccaat tagctgaact
    24061 tggcgtttta ggagtggaaa tggaagcagc ggctctttat tacttaggcg cgaaatacca
    24121 tgtgcagaca ttaagtttga tgaccgttag cgaccatttg atcaccggtg aagaaacaac
    24181 agctgcagaa cgtcaatcta cgttcaatga aatgatcgaa gtaggattgg aaacagcgat
    24241 agcagaataa gaaggaaatg aaaaagctgc cctgcattaa gtaataagaa catccaagca
    24301 aaaatagctc ctcatgtttt tgacttggct ggacttatta ttgcaaatgt aagcttttga
    24361 acaccgttta ccaagaggtt gtgaatctgc cgtttaactc tgagtcacaa ggaacaattt
    24421 caaaaaacag cttttcatgt ttgatgaata ttgtgacttg tgaccgagaa gttggcagga
    24481 gaaaaccgtt tatacgaaaa aagggactgt gacaaatcgt gtcacagtcc cttttttata
    24541 gtgtttttta taggtagtat tttttagcaa ctgttaagtc atcatttaat tcataaacaa
    24601 gtggttgacc tgttggaatt tcaagatcca tgatgtcttc gtcagagata ccttcgatat
    24661 gtttagctag ggcgcgtaat gagttaccat gtgcagctac taaaacagtt ttgttgtcta
    24721 gtaatgctgg agcaatttca tcttgccaga atggcaaagc gcgttctaat gtcactttca
    24781 agttttctcc accaggaata tcgcgtttgt ctaacattgc gtaacgacgg tcatttgctg
    24841 cagaaccttc gtcagtttct tccattaatg gaggaagagt atcgtaagaa cgacgccaga
    24901 tgtgcacttg ttcgtcgccg tatttttcag ctgtttcttt tttgttcaaa ccttgtaatt
    24961 taccatagtg acgttcgttt aagcgccatg atttgatttg tggtacccaa agttgatctg
    25021 aatattctaa gatcaagtta catgttttga ttgcacgagt taaaacagaa gtgtaagcaa
    25081 catcaaattc gattccagct tctttgattt tgcgtccgcc ttcttttgct tcttcgattc
    25141 cttctggtgc tagatttaca tcagcccaac cagtaaattg gttcaatgca ttccattcac
    25201 taagaccgtg acgagaaaaa actaattttg gcatgtttag ctctcctttt aagataggtt
    25261 tatatttctg aaattttcag ttctgtttta ttgtacaatt ttttggaaga gatttccatc
    25321 gaaaaattag ataagattct atgagaaaac aagtagagaa tataaaaaaa cgaacagtgc
    25381 ccacgcaact gttcgttttt aggtattaga tgcataattg ctcgatttct ttttcaggta
    25441 aattgatata tttataacat gttccaactg aaacaccgca ttttgaagaa ataaattgga
    25501 tcgtttcttt tttttcataa tagagacgtc ggattttttt gatcgttttt gcatcgattt
    25561 ttggtcttcc gccgattttt ccttttttac gagcttcatc taatccaact aatgtacgtt
    25621 ctttgatcaa tgcgcactcc atgtttgcta ggttttccat taattggaaa tagatttttc
    25681 ccatttcgcg cgtatcgatt ccttcatcaa gactaatcaa gtgcagcccg cgatctttga
    25741 ataattgcgt gagttctgtt aattgccgcg tagatttgcc taatcgatga agttggcaaa
    25801 tgactagtgc atcgccttgt tgcatgtcag cgatcactga ctccaaatga acagcagtag
    25861 aatcattttg ttccacttca tatgtctcat ggaaaatttc ttgacaacca aagtcagata
    25921 attgatcaac ctgagttgtt aaatcaacgt catttatggt tgtgcgtgca taaccaataa
    25981 ttttcatggt gattcctttc tagcagtgat tttctaactg gatataacag taaaaatgta
    26041 gcataaagta cgtcaaaaag atagtttttt cgcaaatttt ccgctgtctt tttttattgg
    26101 atgatcaagc agtttttctt tatttacgac ggattgcgtc aagaatctca acgccttttt
    26161 ctgagccgac aactacttta gaaaccatgt ttaggaaaag cccatgttct actaccccaa
    26221 caagttcatc taaataggta gctaagcttt ctggctgttc gatgacttct agatgcagat
    26281 caatgatgta atgaccacca tctgtggtta agacttctcc gttttcgtct gtacgcaaga
    26341 cgggttggaa tcttttttct tcaaaaatat gaagtagctg ttgggagcca taagggatca
    26401 cttcaactgg gagtgggaac ttcccaagtt tatcgactaa tttagaagaa tcaacgatcc
    26461 aaatcgtttc ttttgagtac gtagcgacta ttttctcgaa aagcaaagca gcgccgccgc
    26521 ctttgatccc ttgaaaatca gcactgattt catcagcacc gtctattgtc aaatcgacta
    26581 cggggacttc atcaatactc tttaacggta ttcctaattt ttccgcttgt tcttttgtcg
    26641 catttgaagt agtaactcct gtgatacgta aaccttcttc acgcatacgg cgaccaatct
    26701 cttctaccat ataataggcg gttgaaccgg tcccgagacc tacgatcatc ccgtccttta
    26761 cgaatttcgc ggcttcaatg ccagctaatt gttttaaatt catctttgcg tccacctttt
    26821 tttagtttga gcatcgtgct ttcctcacta ttttagcgtg atttacggta aaaagatacc
    26881 attctttttt attccaataa agctttttca aaaaaaattg catctcttgt tgacatgttt
    26941 tttcattcgt gatattctaa caaaggtgct ttatctacag gtttctgtga agaaacgtgc
    27001 tgactgttta tcaaagcata tttgataagg atgcagacat tgcatttatt ttttatcaca
    27061 aaaaaagaac cacctggatg tgtggaacta gacgcaaatc gtgggaagga ggaaacaagg
    27121 aatgcctaca attaaccaat tagtacgtaa acctcgtaaa tcaaaggtgg aaaaatctaa
    27181 ttcacctgct ttgaacaaag gatataacag ctttaagaaa actcaaacta acgtaaactc
    27241 acctcaaaaa cgtggggtag caactcgtgt gggtacaatg acacctaaaa aaccgaactc
    27301 agctttacgt aaatatgcac gtgttcgttt gtcaaactta attgaagtta ctgcttatat
    27361 cccagggatt ggtcataact tacaagaaca cagtgttgta ttattacgcg gtggtcgtgt
    27421 aaaagactta ccaggggtac gttaccatat cgttcgcggt gctttagata ctgctggtgt
    27481 taacgaccgt aaacaaagcc gttctaaata cggaactaaa aaacctaaag cttaatttta
    27541 attattaaac aaatgaaact tgcttctact atatagaagt aattactatg aacaatattt
    27601 cggaaggagg agttacggat gccacgtaaa ggtcctgttg caaaacgtga tgttttacca
    27661 gatcctattt ataactcaaa attagtaact cgcttgatca accgtgtaat ggttgacgga
    27721 aaacgcggga ttgcagctaa cattatctat aatgcctttg acttgatcaa agaatctaca
    27781 ggtaacgatc cattagaagt gtttgaacaa gcaatgaaaa acgttcaacc tgttcttgaa
    27841 gttaaagcac gtcgtgttgg gggttcaaac taccaagtac cagttgaagt tcgccctgaa
    27901 cgccgcgtta ctctaggtct tcgttgggta gtaaactacg ctcgcttgcg cggtgaacac
    27961 acaatggaag aacgcttagc aaaagaaatc atggatgctg caaacaacac aggtgcttct
    28021 gttaaaaaac gtgaagacac tcataaaatg gctgatgcca accgtgcgtt tgctcactat
    28081 cgctggtaag attctctctg tttggtcggc ttttataagt cgacctcaga tagtgtcctt
    28141 atttttagca actagatagt aaagagagga gaaacaagga gaatgaccag agaattttct
    28201 ttacaaaaca ctcgtaatat cggtatcatg gcccacatcg atgctggtaa aacgactgct
    28261 actgaacgta tcttgtacta tactggtaaa atccataaaa ttggtgaaac tcatgaagga
    28321 gcttcacaaa tggactggat ggaacaagaa caagaacgtg gtattacgat cacttctgct
    28381 gctactacag cacaatggaa gggtcaccga atcaacatca tcgacacacc aggacacgta
    28441 gacttcacag ttgaagttga acgttcattg cgtgtacttg atggtgctgt aactgttctt
    28501 gatgcacaat caggtgttga acctcaaact gaaacagttt ggcgtcaagc aacaacttat
    28561 ggtgtacctc gtatcgtatt tgcaaacaaa atggacaaga tcggtgctga cttcttatat
    28621 tcagtatcaa ctttacatga ccgtttgcaa gcaaacgctc acccaatcca attaccaatt
    28681 ggtgcggaag acgacttcac aggaattatc gaccttgtaa caatgaaggc tgaaatgtat
    28741 acaaacgatc ttggaacaga gatcgaagaa acagaaattc ctgaagaata ccgcgaatta
    28801 gctgaagaat ggcgcgaaaa attggttgaa gctgtagctg aaactgatga agaacttact
    28861 ttgaaatact tagaaggtga agaaatcact gaagctgagt taaaagaagg tatccgccgc
    28921 gcaacagtta acgtagaatt ctacccagta ctatgtggtt cagcatttaa gaacaaaggg
    28981 gttcaattac tattggacgc tgttcttgat tacttgccat caccgttaga tatcccagct
    29041 atcaaaggga ttgaccctaa aactgatgaa gaagtagaac gtcctgcaga cgacagcgct
    29101 cctttctcag ctttagcatt taaagttatg actgacccat tcgtaggtcg tttaactttc
    29161 ttccgtgtgt actctggtgt tttacaatca ggttcatacg tacaaaacgc aacaaaaggc
    29221 aaacgtgaac gtgttggtcg tatcctacag atgcatgcca actctcgttc agaaatctct
    29281 gaagtttacg ctggagatat cgctgctgct gttggtttga aagacacaac tactggggac
    29341 acactatgtg atgaaaagag tctagttatt cttgaatcca tggaattccc agaaccagtt
    29401 atccaagtcg ctattgaacc taaatcaaaa gctgaccaag ataaaatggg tgtggcttta
    29461 caaaaactat ctgaagaaga tcctactttc cgtgctgaaa caaacgtgga aacaggcgaa
    29521 acaatcatcg ctggtatggg tgaacttcac ttagatatca tcgttgaccg tatgcgtcgt
    29581 gaattcaaag ttgaagctaa cgtaggtgcg cctcaagtat cttaccgtga aactttccgt
    29641 gctggcactc aagccgaagg taagtttgta cgtcagtctg gtggtaaagg tcaatacggt
    29701 cacgtatgga ttgaatttac accaaatgaa gaaggtgctg gtttcgaatt tgaaaatgcg
    29761 atcgtcggtg gggttgttcc tcgtgaatac attccagctg ttgaaactgg tttgaaagat
    29821 gctatggaaa atggtgtctt agctggctat ccattagtag atatcaaagc taaactttac
    29881 gatggttcat accatgatgt cgattcaaat gaaactgcct tccgtgttgc tgcttctatg
    29941 gcattacgtg cagcagctaa gaaagctaat ccagtaatcc ttgaaccaat catggctgta
    30001 gaagttgtta tccctgaaga ttatttaggt gatgttatgg gtcacgtaac tgctcgtcgt
    30061 ggacgtgttg aaggtatgga agctcgcgct ggcggccaac aagttgttcg tgcgatggtt
    30121 ccacttgctg aaatgtttgg ttatgctaca actcttcgtt ctgctactca aggtcgtggt
    30181 acatttacaa tgacatttga ccactacgaa gatgtaccaa aatcagtaca agaagaaatc
    30241 attaagaaaa acggcggaaa agctgaataa tttcttaaaa ccggatagtc ctgcaaagag
    30301 attatccaaa gagactatat ttttaatata gtttcgtgta aaataattat cgatgatatg
    30361 ggcatgtggt gtaccttgtg tacatcatat acctatcaga caaataaaaa atatattgta
    30421 tttttaggag gacattttaa aatggcaaaa gaaaaatttg accgttctaa accacacgtt
    30481 aacattggta ctatcggaca cgttgaccat ggtaaaacta cattaacagc tgcaatcaca
    30541 actgtactat ctaagaaaaa cggcggccaa gctatggctt acgatcaaat cgatggtgct
    30601 ccagaagaac gcgaacgcgg aatcacaatc tcaacagctc acgttgagta tgaaacagat
    30661 acacgccact acgctcacgt tgactgccca ggacacgcgg attacgttaa aaacatgatc
    30721 actggtgctg ctcaaatgga cggagctatc ttggtagttt ctgctgctga cggcccaatg
    30781 cctcaaactc gtgaacacat cctattgtct cgtcaagttg gtgttcctta catcgttgta
    30841 ttcttgaaca aagtagacat ggttgatgac gaagaattac tagaattagt tgaaatggaa
    30901 gttcgtgacc tattaacaga atacgaattc cctggtgacg atgttcctgt agttgctgga
    30961 tcagctttga aagctctaga aggcgacgct tcatacgaag aaaaaattct tgaattaatg
    31021 gctgcagttg acgaatacat cccaactcca gaacgtgaca acgacaaacc attcatgatg
    31081 ccagttgaag acgtgttctc aattactgga cgtggtactg ttgctacagg tcgtgttgaa
    31141 cgtggacaag ttcgcgttgg tgacgaagtt gaagttgttg gtattgctga agaaacttca
    31201 aaaacaacag ttactggtgt tgaaatgttc cgtaaattgt tagactacgc tgaagctgga
    31261 gacaacattg gtgctttact acgtggtgtt gcacgtgaag acatccaacg tggacaagtt
    31321 ttagctaaac caggtacaat cacacctcat acaaaattct ctgcagaagt atacgtgttg
    31381 acaaaagaag aaggtggacg tcatactcca ttcttcacta actaccgtcc acaattctac
    31441 ttccgtacaa ctgacgtaac aggtgttgtt gaattaccag aaggaactga aatggttatg
    31501 cctggcgaca acgtaacaat ggaagttgaa ttaatccacc caatcgctat cgaaaacggt
    31561 actaaattct caatccgtga aggcggacgt acagttggtg ccggtgtcgt tacagaaatc
    31621 aaagcttaat tcacttaagt tttaaagtaa agcaacattt attcggacgt aatcgctcgg
    31681 aacgaaggtc ttaggatctt tgttccgagc ttttttattt attgcaggat caggaaaaaa
    31741 gacaggagta ttataaatag aagaaacacg aaataaaaga gtcagtattt tctaaatgaa
    31801 actttatgaa aacaaaatgt tttttacaag aaaaagcctt gctttgtgag tttatatata
    31861 ttataatgac aaaggtgcgt ttactttagt gaattgcaca gacgtaatca gaatgatttc
    31921 gtcggctaag aaacgagagg ttgcgacacg cccggacgct ttgccacgaa cgagcgtgac
    31981 ggaaattttc gtggagctat gtctactttt caaaataggc gaaggaggga acaagatggc
    32041 aaaacaaaaa attcgtatcc gtttaaaagc gtatgaacac cgtattttag atcaatcagc
    32101 ggataaaatc gtggaaactg caaaaagaac tggagctagc gtgtctggtc caattccatt
    32161 accaactgaa cgcagtcttt acacaatcat ccgtgcgact gattcacgcg aacaattcga
    32221 aatgcgtaca cacaaacgtc ttatcgacat tgtgaaccca acaccaaaaa ctgttgatgc
    32281 tttgatgaag ctagacttac catctggtgt aaacatcgaa atcaaattat aaaactaaaa
    32341 caaaaataat ggaggtgtac tcatgaccaa aggaatctta gggaaaaaag tgggaatgac
    32401 acaaatcttc actgaatctg gtgaattaat tccagtaact gttgtagaag ctactccaaa
    32461 cgtagtacta caagtgaaaa caatggaaac ggatggctac gaagctattc aagttggtta
    32521 ccaagatatg cgtgaagttt tatcaaacaa acctgcgaaa ggtcatgttg caaaagcaaa
    32581 cacggctcct aagcgcttca ttcgtgaatt caaaaatgtt gagctaggag aatatgaagt
    32641 aggaaaagaa attacagtag atgttttcca agcaggagac attattgatg taacaggtac
    32701 tacgaaaggt aaaggattcc aaggggttat caaacgccac ggacaaagcc gcggaccaat
    32761 ggctcacggt tctcgttacc atcgtcgtcc tgggtcaatg ggtccagttg cacctaaccg
    32821 tgtatttaaa aacaaacgtc ttgctggccg tatgggtggc aaccgcgtaa ctatccaaaa
    32881 cttggaagtt gtacgtgtcg atgcagaaag aaatgttatc ttgatcaaag gtaatgttcc
    32941 tggagctaaa aaatctttaa ttactatcaa atcagctgtg aaagctaaat aattgtagga
    33001 agaaaggagg aactaaggaa tgccgaatgt agcattattc aaacaagatg gaagccaaaa
    33061 cggtgaaatc acacttaacg aagaaatctt cggaattgaa cctaatgaaa gtgttgttta
    33121 cgatgcaatc gtaatgcaac gtgcgtcatt aagacaagga acacacgcgg ttaaaaaccg
    33181 tagcgctgtt cgcggcggcg gacgtaaacc atggcgtcaa aaaggaacag gtcgtgcacg
    33241 tcaaggatct atccgctcac cacaatggcg tggaggtggc gtagtctttg gaccaacacc
    33301 acgttcttac agctacaaac ttcctaaaaa agttcgtcgt ttagcaatga aatctgtatt
    33361 gtcagaaaaa gttgctgaaa acaacttggt agcaatcgaa ggcttgaact tcgacgcacc
    33421 aaaaacaaaa gaattcaaac aagttcttgc taacttatct atcgactcta aagtattggt
    33481 tgttctagaa aaaggtaacg actttgctgc tttatcagca cgtaacttac caaacgtttc
    33541 tgtagtaact tctgataatg tgagtgtgct agacgttgta tcaaatacaa aagtgttagc
    33601 aacacaaact gctcttactc aaattgagga ggtgcttgca taatgaactt actagacgta
    33661 atcaaacgcc cagtgatcac tgaaaaatca atgcttgcca tggatgacaa gaaatacact
    33721 tttgaagtgg acactcgcgc aaacaaaact ttagtaaaac aagcggtaga agctgctttt
    33781 gacgttaaag tcaaaaacgt gaacatcgtg aacgtacgtg cgaaattcaa acgtatgggc
    33841 aaatatgcag gatatacaaa aaaacgtcgc aaagcgatcg ttacattgac tgaagattca
    33901 aaagaaatcc aattattcga agctgctgaa taagcactaa tagataactc attaaattag
    33961 gagggaaaaa cgtggcgatt aaaaagtaca aacctacctc aaatggtcgt cgtaacatga
    34021 caggttctga ttttgctgaa atcacaacat caacacctga aaaatcattg ttacaaccat
    34081 tgaaaaacca tgctggacgt aacaacaacg gccgcatcac tgtacgtcat caaggtggcg
    34141 gacacaaacg ccaatatcgc gtgatcgact tcaaacgtaa caaagataac gttgttgcaa
    34201 ctgttcaaac gatcgaatat gatccaaacc gttcagctaa catcgcgtta gtacactatg
    34261 aagatggagt gaaagcttac atcttagcac ctaaaggact agaagtgggt atgaaacttg
    34321 tttcaggtcc agaagcagat atcaaagtcg gaaatgctct tccattagaa aacattccag
    34381 ttggtactgt tatccacaac attgaaatga aacctggtaa aggtggacaa ttgatccgtt
    34441 ctgctggtac aagtgctcaa gtacttggta aagaaggcaa atacgtattg atccgcttga
    34501 actctggtga agttcgtatg atcttagctg catgccgtgc tacaatcggt tctgtaggta
    34561 acgaacaaca cgaattaatc aacatcggta aagctggacg ctctcgttgg atgcgtaaac
    34621 gcccaactgt acgtggtagc gtaatgaacc ctaatgatca cccacacggt ggtggtgaag
    34681 gtaaagctcc tatcggacgt aaagcaccag tttctccttg gggtcaacca gctcttggtt
    34741 acaaaactcg taacaaaaaa gctaaatcag acaaacttat tgttcgtcgt cgcaaaaata
    34801 aataattact ttgaccatgt gtcgcacatt ttgagaggag gttcaccatg ggtcgtagtt
    34861 taaagaaagg accttttgtc gatgagcatt taatgaaaaa agttgaagct caagcagggg
    34921 ttgaaaagaa aaaagttatc aaaacttggt cacgccgttc aacagttttc ccaagttttg
    34981 ttggatatac catcgcagtt tatgatggac gtaaacatgt accagtttac atccaagaag
    35041 acatggtagg acacaaatta ggtgaatttg cacctacaag aacttatcgt ggacatgctg
    35101 ctgacgataa gaaaacgaaa cgctaatttg aggggaggat aaatccaaat ggcagaacaa
    35161 atcacatcag ctaaagcaac tgcaaaaaca gttcgcactt cacctcgaaa agcccgttta
    35221 gtaattgacc ttatcagagg taaaagtgtc gcagatgcaa tttcaatctt gaaattcaca
    35281 ccaaacaaat ctgctggaat cattgaaaaa gtattgatgt cagcagttgc gaatgcagaa
    35341 aataactttg acttagatgt tgaaaacttg gtagtaagcg aagcttttgt taacgaagga
    35401 cctacaatga aacgtttccg tcctcgtgca aaaggatcag cttctccaat caacaaacgt
    35461 acaagtcata tcacggtagt cgtatcagaa aaataaggag ggataatcag tgggtcaaaa
    35521 agtacatcca attggaatgc gtgtaggcat catccgcgac tgggatgcta aatggtatgc
    35581 tgaaaaagag tatgctgagt tcttacacga agatttaaga atccgtaaat ttatttcaac
    35641 taaacttgct gatgctgctg tatcaacagt tgaaatcgaa cgcgcaacag gtcgcgtaaa
    35701 catttcaatt cacacagcta aaccaggtat ggttattggt aaaggcggtt ctgaagtcga
    35761 aagcctaaga aaagaattaa acaaattaac tggtaaaaga atccatatca atatcgtgga
    35821 aatcaaaaaa ccagatctag atgcaaaatt agtaggtgaa ggaatcgcac gtcaattaga
    35881 aaaccgtgtt gctttccgtc gcgctcaaaa acaagccatc caacgctcaa tgcgtgctgg
    35941 cgctcaaggg atcaaaactc aagtatctgg tcgtctaaac ggagcagata tcgctcgttc
    36001 agaaggatac tcagaaggaa ctgttcctct tcatacttta cgtgcggaca ttgattacgc
    36061 atgggaagaa gcagatacaa catacggaaa actaggagtt aaagtgtgga tctatcgtgg
    36121 agaaattctt ccaactaaaa aaaacactga gaaaggaggg aaataatcat gttagtacct
    36181 aaacgtgtaa aacaccgtcg tgaattccgc ggaaaaatgc gcggggaagc taaaggcgga
    36241 aaagaagtag cattcggtga atacggtttg caagctgttg attcacattg gatcacaaac
    36301 cgccaaatcg aagctgctcg tatcgcaatg actcgttaca tgaaacgtgg tgggaaagta
    36361 tggattaaaa ttttccctca caaatcttat actgccaaag caattggggt acgtatgggt
    36421 tctggtaaag gggcacctga aggatgggtt gcaccagtaa aacgtggtaa aatcatgttt
    36481 gaaatcgcag gcgttcctga agaagtagct cgtgaagcgt tacgtctagc ttctcacaaa
    36541 ttaccaatga aaactaagat cgtaaaacgt gaggaaatgg gtggtgaatc gaatgaaggt
    36601 taaagaaatc agagaattaa ccactgccga aatgcttgat caagaaaaac aattaaaaga
    36661 agaattgttt aatcttagat tccaattagc aacaggtcaa ttagaaaaca ctgcacgtat
    36721 taaagaagta cgtaaatcga ttgcacgcat caaaactgtg ttgcgtgaac aagctaagta
    36781 attatggaag gaggccatta agcgtatgac tgaaggaaga aatcaacgca aagtttatca
    36841 aggtcgcgtg gtttcagaca aaatggataa aacaattacc gttgctgtcg aaacaaagaa
    36901 aaaccaccct atctatggca aacgcatgaa ctattctaag aaatacaaag tgcatgatga
    36961 aaacaacaca gcaaaagttg gcgacatcgt gagaattatg gaaactcgtc cattatcagc
    37021 tacaaaacgt ttccgtttgt tggaagtagt cgaagaagca gttattatct aataacacga
    37081 gattttccta tatagattga atgcaaaatc tgaaaggagg atacacaacg tgatccaagc
    37141 agaaagtcgt ttaaaagtcg ctgataactc aggcgcacgt gaaattttga cgatcaaagt
    37201 ccttggtgga tctggtcgta aaactgctaa catcggtgat gtgatcgttg ctacggttaa
    37261 acaagcaacg ccaggtgggg ttgtcaaaaa aggtgacgtc gttaaagccg ttatcgttcg
    37321 aacaaaatca ggagctcgtc gtacagacgg ttcatatatt aaatttgatg aaaatgctgc
    37381 agtgattatt cgtgatgata aaagccctcg tggaacacgt atctttgggc cagttgcacg
    37441 tgaactacgt gaaaacaact tcatgaagat cgtttcacta gcaccagaag ttttataatc
    37501 ttgagacact tatcaaagga ggtgcgaaac agttatgttt gttaaaaaag gcgataaagt
    37561 taaagttatc actggaaaag acaaaaacaa agaaggcgtt gtactagcag cgttcccgaa
    37621 aaaagataaa gttattgtcg aaggtgtaaa tgtcgttaaa aaacaccaaa aaccttctca
    37681 agctgctcct caaggtggaa ttgttgagat ggaagcgcca attcatgttt ctaacgtgat
    37741 ggtggttgac tctactggtg tagctggccg agttggctac aaagaagtag acggcaaaaa
    37801 agtccgtgtt tctaaaaaaa ccggtgaagt tttagataaa taaaagttta aggaaggagg
    37861 gtcttactga atgaaccgcc taaaagaaaa atatcttaaa gaagtaactc catcattgat
    37921 ggaaaaattt aactatagct ctgttatgca aacacctaaa gttgaaaaaa tcgtcatcaa
    37981 catgggtgtt ggtgatgcgg tatcaaacgc taaaaactta gataaagcag ttgaagaatt
    38041 aactttgatc actggtcaaa aaccaatgat tacaaaagct aaaaaatcaa tcgctggatt
    38101 ccgtttacgt gaaggaatgc caattggtgc aaaagttaca ttgcgcggag aaagaatgta
    38161 cgaattctta gacaaattgg tttctgtttc actaccacgt gtacgtgact tccatggtgt
    38221 aagtaaaaaa gcctttgacg gtcgtggaaa ctatacttta ggtattaaag aacaattgat
    38281 cttcccagaa gtagattatg atttagtaga taaagtacgt ggtatggaca tcgttattgt
    38341 aacaacagca aactctgatg aagaatctcg tgagttgttg acacaattag gcatgccatt
    38401 ccaaaaataa ttaaaggagg cgaactacgt ggctaaaaaa tcaatgattg ctaaaaacaa
    38461 acgtcctgca aaattttcaa cacaagctta tactcgttgc gaacgttgcg gacgtccaca
    38521 ttcagtttat cgtaagttcc atctttgccg tatttgcttc cgcgaacttg cctataaagg
    38581 tcaaattccc ggcgtgaaga aagctagctg gtaaaaagta aattcgcata agaaggaggt
    38641 aaaagatcaa tggtcatgac agatccaatt gcagattttc taactcgtat ccgtaacgca
    38701 aacatggtta aacatgagtc tttagaagta cctgcatcaa aaattaaacg tgacatcgct
    38761 gaaatcttga aacgtgaagg tttcgttcgt gatgttgaat acatcgaaga tgacaaacaa
    38821 ggcgtgatcc gtgttttcct aaaatttggt aaaaacggcg aacgtgttat cacaaactta
    38881 aaacgtatct ctaaaccagg tttgcgtgct tatgtcaaag ctgacgaagt accaaaagta
    38941 ttgaacggtt taggtatcgc aatcatttcg acttctgaag gtgttgtcac tgataaagaa
    39001 gctcgtgaaa aaaatatcgg cggcgaagtt atcgcttacg tatggtaatc aagtagaatc
    39061 tacaaggagg tgtctttaag tgagccgtat cggaaataaa gtcgttgtta tccctgaagg
    39121 agtaacagtt actcaagacg gaaacaacgt tacagttaaa ggaccaaaag gtgaattgac
    39181 tcgtactttt tcagcagata tcaaaatgaa tatcgaagga aacgaagtaa ctttcactcg
    39241 tccaaacgac agtaaagaaa tgaaaacaat tcatggaaca actcgtgcga acttcaacaa
    39301 catggttgta ggtgtcagcg aaggtttcca aaaagcgtta gaactaatcg gggttgggta
    39361 ccgtgcacaa ttacaaggat caaaacttgt attgaacgtt ggttactcac atccagtaga
    39421 aatcacacca ccagctggag taactgttga agtaccagct aacacacaag taattgttaa
    39481 aggtgcgaac aaagaagaag ttggcgaatt agctgcaaac attcgtggaa ctcgtcctcc
    39541 agaaccttat aaaggtaaag gtattcgtta tgttggcgaa tatgtacgcc gtaaagaagg
    39601 taaaactggt aaataatcgt ttagaaaaat tgcatagaag ccagcagcag gaaaaaggca
    39661 tttggctgaa gtttaccttc aaaaaaatac atttttactt gtgccgcagc ttctattttt
    39721 cgaaacgtat ttactgcttg aaatagtagt acaataaaaa taaagaggtg acaattgtga
    39781 ttacaaaacc agataagaac aaaacacgtc aaaagagaca tcgtcgtgta cgtaacaata
    39841 tctctggtac tgctgagcgc ccacgcttga acgtttttcg ttctaacaaa aacatctacg
    39901 ctcaaattat tgatgacgta gcgggtgtaa cgctagcaag tgcctctacc ttggataaag
    39961 aaatttcagg tggaacaaaa acagaagcag cacaagctgt cggtaaacta gttgctgaac
    40021 gtgcagctga aaaaggcatt aaagtagtag tctttgaccg tggtggatac ctttaccatg
    40081 gccgtgtgca agctttagct gaagctgctc gcgaaaatgg actagaattt tagaagaagg
    40141 aggaatacca ttcatggttt atatcgatcc aaaacatttg gaattagaag accgcgttgt
    40201 tgcaattaac cgtgtaacaa aagttgttaa aggtggacgt cgtctacgtt ttgctgcttt
    40261 agttgttgtc ggtgacaaaa acggacacgt agggtttggt acaggtaaag ctcaagaagt
    40321 tcctgaagca atccgtaaag caattgaaga tgcgaagaaa aacttagttg aagtacctat
    40381 ggttggttca acaatcccac acgaagtaat cggtgctttt agtggtggta gaatcctaat
    40441 gaaacctgct gtagaaggtt ctggggttgc tgctggtgga ccagttcgtg ccgtattaga
    40501 attagctggg gtagcagata tcacttctaa atctttaggc tcaaatacac caatcaacgt
    40561 tgttcgcgca acagttgaag gtttgaaaca attgaaacgt gcagaagaag ttgcagaact
    40621 tcgcggcaaa tcagttgaag aattaatcgg ataaggagga caacaataat ggctgaatta
    40681 aaagttactt taaaacgcag tattatcgga cgtcctcaaa accaacgcga tacagttaaa
    40741 gcgttaggtc ttacaaagat taacagttca gtggttaagc cttctaatga agcaattaaa
    40801 ggcatgatca atactgtttc tcacctagtg gacgttgaag aaatttaatt tagaaaaatc
    40861 ataactagaa cattaaggag gtgccaaacc tatgaaactt catgaattaa aacctgctga
    40921 aggttcacgc caagtacgta accgtgttgg tcgtggtact tcatctggta acggaaaaac
    40981 tgccggacgc ggacaaaaag gacaaaaagc tcgttcaggc ggcggtgtgc gtttaggatt
    41041 tgaaggggga caaacaccat tgttccgtcg tttaccaaaa cgaggattca caaacgtgaa
    41101 ccgtaaagac tatgcagtca ttaatcttga tatattgaac cgctttgaag acggagctga
    41161 agtaactcct gttgctttag ttgaagctgg aatcgtgaaa aacgaaaaag ctggaatcaa
    41221 agtattagct aatggggaac taaacaagaa attaactgtg aaagcagcaa aattctctaa
    41281 agcagctcaa gaagcaattg aagcggctgg tggatcaatc gaggtgatct aatgtttaga
    41341 ctattaaaag atgcttttaa agtaaaagac attagatcga aaatcctatt tactgtattt
    41401 gtgttgtttg tatttcgcct aggtgcacat attactgtac caggcgtaaa tgctgcttca
    41461 ttgcaaaacc tttcttcttt gccatttttc aacatgttga acttggtaag tggtagtgcg
    41521 atgcaaaact tttccatttt ctcaatgggg gtttcaccat acattactgc ttctatcgtc
    41581 attcagcttc ttcaaatgga catcgtgcct cgatttgttg aatggtcgaa acaaggggaa
    41641 gttggtcgta aaaaactgaa tcaagcgact cgatatctga cattagtatt ggcatttatc
    41701 caatctgtcg gtatcactgc tggattcaat caatacgctc aattaggttt cgtgaataat
    41761 cctaacgtag caacttacgt aacgatcggt ttgattctaa cagccggtac gatgtttgtt
    41821 acttggctag gagaacagat cacagaaaaa ggtatcggaa atggcgtatc aatgatcatt
    41881 tttgcaggta tcatttctag attgcctgaa agtatcagag aaatttatga agattacttt
    41941 ataaatattg atccttcaga catatggaaa tctgctattt ttgtggccat tttactagta
    42001 gcggtcttgt tgatcgtgac attcgtaaca tttttccaac aagctgaacg caagatcccg
    42061 atccaatata cgaaacgcgt agctggcgcg cctacaagca gctatctgcc gttgaaagta
    42121 aatgcagctg gagttattcc agttatcttt gctagttcgt ttattgctac gccaaatgct
    42181 gttttacaag cattgagcgg tagattcggt tctgaaaact ggtacaaagt gatgatggag
    42241 atctttaact ataatacagc acctggtgct acgatttata cgattctgat cgttgccttc
    42301 actttcttct acgcctttgt tcaagtaaac cctgagaaat tagcggaaaa cttgcaaaag
    42361 caaggaagtt atataccaag cgtacgccct ggtaagggga ctgaagagta tgtctcaaga
    42421 ttactgatgc gtttaagtac agttggtgca gtcttccttg gtttagtggc attgcttcca
    42481 atcattgctc aaatggtttg ggatcttcca caatcaatcg gattaggcgg tacaagctta
    42541 ctgatcgtta tcggtgtagc tttagaaact gcgaaacagt tagaaggctt aatgctgaaa
    42601 cgtaaatatg ttggattcat tgagtaagaa agcgtgttga ggtttcccct caacacacgt
    42661 tctcacacat ttattaggag ggaaaacaat gaacctcatt ttaatggggc tgccaggcgc
    42721 aggtaaagga acacaagctg aaaaaatcat tgatgcttat ggtattccgc acatctcaac
    42781 aggagatatg ttccgcgcag cgatgcaaaa cgaaacagct cttggcctgg aagcaaagtc
    42841 ttatatggat aaaggtgcat tagttcctga tgaagtaaca aatggaatcg tgaaagagcg
    42901 actagctgaa ccagatacag agaaaggctt cttattagat ggctttccac gtacgctaga
    42961 tcaagcaaaa gctctggacg caatgctaaa agatttgaat aaaaaaattg atgctgtcat
    43021 cgatatccat gttggtgaag aaatcttggt cgaacgtcta gccggccgat ttatctgcag
    43081 caattgtgga gcaacttacc ataaaatttt caaccctaca aaagttgaag acacatgtga
    43141 tcgttgcggt gggcatgaat tctatcaaag agaagatgat aaacctgaga cggttaaaaa
    43201 tcgtctggct atcaacatca aaaatagtga accaatcttg gcttattata aagaacaagg
    43261 tttgctaaac actattgatg gtgctcgtga aatcgatgct gtatttgcag atgtacaaaa
    43321 aatcattgaa aaatagcacg attgcccgta gccgacttgc attatgcagt tactcttgtc
    43381 aagttcaata aattatgata gaatatgtca gtccgacttc tagagaatcc tctagatgat
    43441 ccattttgag aattttgagg tgggaactgc agtttccgcc attttatcgt gtgaaaatgc
    43501 gaaacaagta caaggaggta ctgtgcgtgg caaaagaaga tatgattgaa gtcgaaggta
    43561 cagtcgtcga aactttgccg aatgcaatgt ttaaagttga actagaaaac ggacaccaag
    43621 ttcttgctac tgtttcaggt aaaattcgta tgcattacat ccgtatctta cctggtgaca
    43681 aagtaacggt tgaattgtct ccatacgatc ttaaccgtgg ccgtattact tatcgcttta
    43741 aataattgta ctccgtaaaa ctacaggagg tattatcatg aaagtaagac catcagtaaa
    43801 accaatgtgc gaacattgta aagtaattcg tcgtaaagga cgcgttatgg tgatttgccc
    43861 agcaaatcca aaacataaac aacgtcaagg ataattggag gtgctataaa tatggctcgt
    43921 attgcaggag tagatattcc tcgtgataaa cgtgtagtag tttcacttac ttatatctat
    43981 ggtattggta acactactgc taaaaagatc ttagctgatg ctggtgtatc tgaagatgtt
    44041 cgcgttcgtg aattaacgaa tgaacaaaca gatgctatcc gtgcagaagt agataaatta
    44101 aaagttgaag gggatcttcg tcgtgaagtg aacttgaaca tcaaacgttt gatggaaatc
    44161 ggttcttacc gtggaatccg tcatcgccgt ggattgcctg ttcgtggaca aaacacgaaa
    44221 aacaatgcac gtactcgtaa aggcccagct cgcgctatcg ctggcaagaa aaaataattc
    44281 ttaagtgaag gaggttaaaa cttcatggca gcaaaaaaag tgaatcgtaa acgccgtgtg
    44341 aagaagaata tagaagcagg tattgcacat atccattcta cattcaataa cactatcatc
    44401 atgatcactg atactcacgg aaatgcatta gcgtggtcat cagctggttc attaggtttc
    44461 aaaggaagca aaaaatcaac tccttttgcc gctcaaatgg cagcagaaac tgctacaaaa
    44521 gcagcaatgg aacacggatt aaagactgtt gaagtaacag ttaaaggacc tggttctgga
    44581 cgtgaagcag caattcgttc attacaagct acaggtttag aagtgactgc aattcgtgac
    44641 gtgactccag ttcctcataa tggtgcccgc cctccaaaac gccgtcgtgt ttaatgagtg
    44701 ccgctcattt tgagttttat cagtaacgtc attgaacaag acacttttcg ttttgaaagg
    44761 ggtaaagata agaatgattg agttcgaaaa accaagaatc gcaaaaattg atgaagaaaa
    44821 agattatggc aagttcatcg ttgaacctct tgaaagaggg tatgggacta ctttagggaa
    44881 ttccctacgt cgtattttat tatcttcttt gccaggtgct gccatcacta atattcaaat
    44941 cgatggtgta ctgcatgaat tctctaccat caaaggtgtt agagaagacg tcactcaaat
    45001 catcttgaac attaaaggct tagcgctgaa aatgtatggc caagaagaaa aaacccttga
    45061 aatcgatatt accggacctg ctacagtaac tgctggcgat attatcgttg atagtgatgt
    45121 agaaattctt aacaaagata tgtacatctg tagtgtctct gaaggagcta cgttccatgc
    45181 tcgcttaaca gtgaaacctg gacgtggtta tgttcaagca gatgaaaata aaaaagaaga
    45241 tatgccaatt ggcgttcttc cagtcgattc aatctacaca cctgttcgtc gtgtgaacta
    45301 tcaagttgag aacacacgtg ttggacaccg tgaagatttt gataaattga cgatggagat
    45361 ttggacagat ggttcaattg aaccgttgga agcaatgagt ttgtctgcga aaatcatgac
    45421 tgaacatttg gatatttttg tgaacttaac tgatgaagca aaaaatgctg aaatcatggt
    45481 cgaaaaagaa gaaacacaaa aagaaaaaat gttggaaatg acgatcgaag agttagactt
    45541 gtctgttcgc tcttacaatt gtttgaaacg tgcaggaatc aatactgtac aagaacttac
    45601 aaataaatct gagcctgaaa tgatcaaagt ccgtaactta ggacgtaaat cattagaaga
    45661 agttaaagca aaattgcacg acttaggttt aggtttacgt aaagaagatt aaaacctttt
    45721 acgaaggagg gaaaccaacg tgagttatcg taaactagga cgcacatcta gccaacgtaa
    45781 agcgatgttg cgtgatttaa caactgattt attaatcaac gaacgtattg tgactactga
    45841 agctcgtgcg aaagaagttc gctcaactgc agaaaaaatg atcactttag gtaaacgcgg
    45901 agatttgcat gcacgtcgtc aagctgcggc tttcgtacgt aatgaagttg ccagcgtgcg
    45961 tgaagaaaat gaggacatcg tcattgaatc agctttacaa aaactgttca acgatattgc
    46021 acctcgttac gcagaacgtc aaggcggata cacacgcatt ttgaagacag aaccaagacg
    46081 cggtgatggt gcaccaatgg ttgtcttaga acttgtctaa aatcacacta ataacatcac
    46141 tttatagatg attcttttag agtgttatga tgttggaaga tatttttccg agtctagctc
    46201 agcgctgctc ctcaagcgaa tatcgcttgg ggagtaagca ctcatcataa agtgtttttt
    46261 tataccttca attacctgtc atgacagata tgtttgaagg cataaaaaaa cattttaagc
    46321 gagaaataat tgaaaatttt gtcttttttt gatagtgtta gtaggaactt taggatgaag
    46381 aaggagtaat catggagcca attattgaat tagaaaagat aaattataaa taccagccag
    46441 atgatcttcg ccccgcattg aaagatgtct cctttacaat tgataaaggt gagtggatcg
    46501 ctattattgg acacaatggt tcaggaaaat cgacacttgc caaaacgatc aatggattgc
    46561 ttctgccaga atcagggatc gtgaaagtgg gaaatcaaat attggatgaa gaaaatattt
    46621 ggacgatccg acagatggtt ggaatggttt ttcaaaatcc agacaatcag tttgttggtt
    46681 cgacagtaga agatgacgtt gcttttggtc ttgaaaatca agggattccc agagaagaaa
    46741 tgctagtgcg tgtgaaagat gcacttgaga aagttagaat ggctgagttt gcttcacgcg
    46801 agcctgctcg tttatcagga gggcaaaaac aacgtgttgc cattgccggc gtggttgcct
    46861 tacgacctga tatcattatt ttagatgaag caaccagtat gctagatcca gaaggtcgtg
    46921 aagaagtgat ctctacgatc aagaagatca aagaagaaag tcaattgacc gttatatcta
    46981 tcactcatga tattgatgaa gcagctaatg ccaatcggat actagtgatg agacaaggcg
    47041 aacttgtccg tgaaggtaca ccaaaagaaa ttttttctgc tggtcctgaa ctgatcgact
    47101 taggtctaga tctaccattt cctgaaaaac tgaagagcgc actgaaagaa cgtggggttg
    47161 atgtgcccag tgaatatatg acagaagaaa ggatggtgga ttggttatgg acatccgttt
    47221 tgaacaagta gacttcactt atcagccgaa tacaccattt gaacaaagag ccttatttga
    47281 catcaatatg acgatcaaag aaaacagtta tactgcatta gtagggcata ccggaagcgg
    47341 gaaatcaacc ttacttcagc atttgaatgc gcttgttaag ccaacaagcg gtacagtcca
    47401 tattggagaa cgagatattc agccggatac ggataataag aatttaaagc ccatccgaaa
    47461 aaaagttggc atcgtctttc agtttccaga agcacagcta ttcgaagaaa cggtagcaaa
    47521 agacattgct ttcggtccta aaaactttgg tgtcagcgaa gaagaagcac tagtcctagc
    47581 aaaagaaaca ttagaacaag ttgggctgga tgaaagctat ttggaacgtt cgccatttga
    47641 actttcagga gggcaaatgc gtagagtagc aatcgctggt gtgcttgcca tgaggccgga
    47701 agtacttgta ttggatgaac caacggcagg acttgatccc cagggtagaa aagaaatgat
    47761 ggagatgttt tggcgtcttc ataaggaaca gcagatcact attgtattag ttacgcattt
    47821 aatggatgat gtagccaatt ttgcagatta tgtctatgtg ttggaaaagg gacgaatcgt
    47881 taatagcggg gagccgcaag aggtctttca aaacattgaa tggctaaaag aaaaacaact
    47941 aggcgtacct actgccaccg agtttgcaga agaattaatg gctaaaggga tgaactttgc
    48001 taccttgcct ttgacagctg aagaattagc agacgctatc gtccattatg ctggaggaaa
    48061 tgcccatgat gaataaattg atatttggtc gttatatgcc tggagattcc ttgatccatc
    48121 gattggatcc ccgagctaaa ttattagcca gtttttattt tatcggaatc atttttttag
    48181 caaataattg ggaaacgtac cttttgttgg catttttcac attactttct gtcttcttgt
    48241 caaaagtaga tttgaaattt tttatccgag gcattcgccc attgatctgg ctaatcctct
    48301 tcactgtagc tttgcaggtc ttgtttacaa gtggcggaga aacttattgg agttggggtg
    48361 ttttccatat cactgaattt ggtgtgatga acggcctctt tattttctgt cgattcgtgt
    48421 tgatcatttt tatgtcgact ctactcacgc ttactacacc gcctttggaa ttatcggatg
    48481 cgattgagta cttgcttcgt ccattgaaag ccgtacggtt cccagtccac gaaatttcat
    48541 tgatgctgtc gattgctctt cgttttgtgc ctacattgat ggacgaaaca gaaaagatca
    48601 tgaacgctca gcgcgctcgc ggtgttgatt ttggtgaagg aaacctagtt cagaaaatga
    48661 aagcagtcat tcctttgctg attcctttat ttgtcagcag cttcaaccgt gcggaagatc
    48721 ttgcgactgc tatggaagca agaggctaca aaggtgggga aggaagaacg aaatatcgtg
    48781 tattgcattg gcataataga gacacgatgg ttatcattgc ttttgtatta ttaactgtgc
    48841 tactgatctt tttgagagga taaacgttca gtgggccgct atctattctt ttcttgctga
    48901 tctgtttgca agaaaggatg cgagcagtgt atgacaagaa atattagggt ctgtggcaga
    48961 ctaaggtcac aggcctcttt cttttatctg aaaagaaaga acgaaaaaat tttataaaaa
    49021 aatcattatt ccagataacc ttttaggaac aaaggagaga aaaacatggt acgttacaaa
    49081 gcaatcattg catacgacgg aacaaatttt aatggattcc aaaaacagcc aaatgggcgt
    49141 actgttcaag aagaagtaga aaaaacatta caaaaaatgg caaatggaaa agaaatcacg
    49201 gtctttggtt cgggaaggac agatgccgga gtacatgcga ttgggcaagt aatccatttt
    49261 gattatccag aggagcgtcc gttagaacga atgcgtttcg cgctagatac ccagtcacca
    49321 gaggatattg ctgtaagaca agtagaaatt gtttcagaag acttccacgc aagatatttg
    49381 gtcaaagaaa agacgtatca atttcgagtg gatataggga aaccacgcag tccttttcga
    49441 cgccattatg caagttattt tccttaccct cttgatttgg aaaaaattca gcgggcgctt
    49501 cctgatttat tagggactca cgatttcacc tctttttgtg catcaggaag ctcgatagag
    49561 gataaagtac gtacgatcta cgaggctaag atggaggtaa atgaaacaaa agacgaattg
    49621 ttgtttacat ttaggggaaa tggcttcttg tataagatga tacggatctt agtaggaacg
    49681 cttttgaaaa ttggcaatgg ccgattgcct gaagatagta tcccagatat tattgcgaaa
    49741 aaagatcgta atgcagcagg acctacagca catcctgaag gactttattt gtatgaagtg
    49801 aaatatgaat aagaggttgt gacagaagtg gtcagcttca agaaataaga aggaatttac
    49861 gaaaattact tctcaaaatt ttgcaaaatt tcggcttatt ttcgaaggag ctacttctgg
    49921 aacaccgtga atcagaggtt gtgaaaaagc tgccctgcat caagtaataa gaacaaccaa
    49981 acaaaaatag ctcgtcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt
    50041 tgaacaccgt ttaaggaaga ggttgtgaaa tcagcgtttt gacctgagta ttagagaaac
    50101 aaacggaaaa atagttcctc atattttgcc gtttgttgag ctaataccga aggtcagctg
    50161 attgaacacc gtttaagaaa gaggtcgtga gcctgtcatt taactctgag tcacaagtaa
    50221 caatttcaaa aaacagcttc tcatctttga tgaatatcgt gacttgtgga cgaggcgttg
    50281 ataagtgaat catctttttg ttacctattt tttctgtaac caaaaaacga tggaacgttg
    50341 ttttgattgc ccttaatgag gacagtcgga acaggtttgt catttttata tttaaatggc
    50401 acaaattttt ctaattattt gtcatttagc gctgaaaatt tttgctattt atctaaaaaa
    50461 gtgataacta cttaagatga agcagaatat ttacgccata cggcatacaa ccgcgaaaaa
    50521 tataaaaaaa agaaaacgat tgaacgcgtt tttgcagtcg caaaggaaaa gcatggaatg
    50581 cgctacatca agtatcgaga cttggaaaac aatcaggtgt atacgctgat tgtttttgct
    50641 gcaatgaatc tgaaaaagtt gtccacttgg cagttggaac atatgtcttc atatctttta
    50701 ttatacaaaa atagcaaaag caccagtcta cactcttagt aaagaggaaa ctgatccttt
    50761 tgtctacatt cttaaagtac ttaaactaag tactttattt tactctttag gattgataca
    50821 gtagcatcta tccctttatt aataatcttt tattttttta aataaagatg ttgtctccat
    50881 cttcaggcac taaaactttt tcggaaattc ctttttcttt attgaaagac tttaattctt
    50941 ctcttgacag tccccaatgg tttacagctt ccatatgaac ggcaataatt gtggaatctg
    51001 gtattgcttt atgcaattca tataaatcgt ctttccccat aataagagat tctccaacta
    51061 aaaaatgatt atctccagca tttgctacta tgatttctgg attatactga tcaatagttt
    51121 gtttaacagc ttcataccaa actgtatctc ctgtaaagta tagtgtcttc tcagtcgaat
    51181 gtttgaaaac aataccgcaa acattaccta cataattcaa gatttctcct ctgccatgtt
    51241 tgccttttgt tttaaccaat tgtatagatt caaaaactgt gtcttctcgt agtacctcca
    51301 catttttaaa accatatagt cgaatttcat tcgcatcatt ttcatcttgc acaaataatt
    51361 ttatttcttt aggtaggacc tctttcgcta tatcgtccca atgatctaga tgtaaatgtg
    51421 ttacaataac agcatcaata ccgttgataa tatcttcgac tggcattggc aaatcaacta
    51481 gaggattcat ttgatctttt cttggtgatg gaaaaggacc tttcgaaata aatggtggaa
    51541 gtgttccttt ttccgctaac attggatcaa ttaaaaattt tttacctcca tagtctaaga
    51601 tagctgttgc attacgaatg tgatgtatat tcataaacgt tgtctccttt ttgttgatat
    51661 gaaatatttt tagtataatt caattccata caataaataa accgaacaaa aaaagtcttt
    51721 tactattttt acttaattta tgaaaggttg tttaccatgt tagaccaaac agatataaat
    51781 atcattgagg aactatcaaa aaatagtcga atcacaatga aagaacttgg agaaaaagta
    51841 catttgactg gacccgctgt ctcggcgaga gtgacaaaac tagaggaaag tggagttatt
    51901 gaaaattata cagtaaaatt aaatatggaa aagctagggt tttcgattca cgctttttta
    51961 attataatta cgcaaaattt
//
LOCUS       DAFLWQ010000009        50224 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.010, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000009 DAFLWQ010000000
VERSION     DAFLWQ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.010"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(240..1940)
                     /locus_tag="L1V16_000552"
     CDS             complement(240..1940)
                     /locus_tag="L1V16_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274916.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            2447..3607
                     /locus_tag="L1V16_000553"
     CDS             2447..3607
                     /locus_tag="L1V16_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1274917.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            3623..4066
                     /locus_tag="L1V16_000554"
     CDS             3623..4066
                     /locus_tag="L1V16_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1274918.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(4549..5079)
                     /locus_tag="L1V16_000555"
     CDS             complement(4549..5079)
                     /locus_tag="L1V16_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HBN1274919.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            5184..5735
                     /locus_tag="L1V16_000556"
     CDS             5184..5735
                     /locus_tag="L1V16_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBN1274920.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(5888..6361)
                     /locus_tag="L1V16_000557"
     CDS             complement(5888..6361)
                     /locus_tag="L1V16_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1274921.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            6499..7971
                     /locus_tag="L1V16_000558"
     CDS             6499..7971
                     /locus_tag="L1V16_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBN1274922.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            7968..8678
                     /locus_tag="L1V16_000559"
     CDS             7968..8678
                     /locus_tag="L1V16_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HBN1274923.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            9030..9314
                     /locus_tag="L1V16_000560"
     CDS             9030..9314
                     /locus_tag="L1V16_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HBN1274924.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(9631..10014)
                     /locus_tag="L1V16_000561"
     CDS             complement(9631..10014)
                     /locus_tag="L1V16_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HBN1274925.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(10016..10600)
                     /locus_tag="L1V16_000562"
     CDS             complement(10016..10600)
                     /locus_tag="L1V16_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HBN1274926.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(10647..12122)
                     /locus_tag="L1V16_000563"
     CDS             complement(10647..12122)
                     /locus_tag="L1V16_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBN1274927.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            12303..12614
                     /locus_tag="L1V16_000564"
     CDS             12303..12614
                     /locus_tag="L1V16_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274928.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(12729..15065)
                     /locus_tag="L1V16_000565"
     CDS             complement(12729..15065)
                     /locus_tag="L1V16_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1274929.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            15207..15875
                     /locus_tag="L1V16_000566"
     CDS             15207..15875
                     /locus_tag="L1V16_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1274930.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            15878..16921
                     /locus_tag="L1V16_000567"
     CDS             15878..16921
                     /locus_tag="L1V16_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1274931.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(17158..18039)
                     /locus_tag="L1V16_000568"
     CDS             complement(17158..18039)
                     /locus_tag="L1V16_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1274932.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            18198..18926
                     /locus_tag="L1V16_000569"
     CDS             18198..18926
                     /locus_tag="L1V16_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBN1274933.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            19082..19399
                     /locus_tag="L1V16_000570"
     CDS             19082..19399
                     /locus_tag="L1V16_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBN1274934.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            19392..20000
                     /locus_tag="L1V16_000571"
     CDS             19392..20000
                     /locus_tag="L1V16_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBN1274935.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            20055..20846
                     /locus_tag="L1V16_000572"
     CDS             20055..20846
                     /locus_tag="L1V16_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBN1274936.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            20984..21472
                     /locus_tag="L1V16_000573"
     CDS             20984..21472
                     /locus_tag="L1V16_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBN1274937.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            21523..22395
                     /locus_tag="L1V16_000574"
     CDS             21523..22395
                     /locus_tag="L1V16_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBN1274938.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            22571..22933
                     /locus_tag="L1V16_000575"
     CDS             22571..22933
                     /locus_tag="L1V16_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBN1274939.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            22942..23694
                     /locus_tag="L1V16_000576"
     CDS             22942..23694
                     /locus_tag="L1V16_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1274940.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            23708..25510
                     /locus_tag="L1V16_000577"
     CDS             23708..25510
                     /locus_tag="L1V16_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1274941.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            25787..26827
                     /locus_tag="L1V16_000578"
     CDS             25787..26827
                     /locus_tag="L1V16_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBN1274942.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(26879..29023)
                     /locus_tag="L1V16_000579"
     CDS             complement(26879..29023)
                     /locus_tag="L1V16_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBN1274943.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(29380..30753)
                     /locus_tag="L1V16_000580"
     CDS             complement(29380..30753)
                     /locus_tag="L1V16_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1274944.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(30753..31148)
                     /gene="rbsD"
                     /locus_tag="L1V16_000581"
     CDS             complement(30753..31148)
                     /gene="rbsD"
                     /locus_tag="L1V16_000581"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HBN1274945.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(31176..32093)
                     /gene="rbsK"
                     /locus_tag="L1V16_000582"
     CDS             complement(31176..32093)
                     /gene="rbsK"
                     /locus_tag="L1V16_000582"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBN1274946.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(32201..33214)
                     /locus_tag="L1V16_000583"
     CDS             complement(32201..33214)
                     /locus_tag="L1V16_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBN1274947.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(33295..33894)
                     /locus_tag="L1V16_000584"
     CDS             complement(33295..33894)
                     /locus_tag="L1V16_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBN1274948.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            34080..34781
                     /locus_tag="L1V16_000585"
     CDS             34080..34781
                     /locus_tag="L1V16_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1274949.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            34791..37502
                     /locus_tag="L1V16_000586"
     CDS             34791..37502
                     /locus_tag="L1V16_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1274950.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            37953..39581
                     /gene="treC"
                     /locus_tag="L1V16_000587"
     CDS             37953..39581
                     /gene="treC"
                     /locus_tag="L1V16_000587"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBN1274951.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(39641..40822)
                     /locus_tag="L1V16_000588"
     CDS             complement(39641..40822)
                     /locus_tag="L1V16_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1274952.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            41074..42597
                     /locus_tag="L1V16_000589"
     CDS             41074..42597
                     /locus_tag="L1V16_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBN1274953.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(42666..43394)
                     /locus_tag="L1V16_000590"
     CDS             complement(42666..43394)
                     /locus_tag="L1V16_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1274954.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(43407..44687)
                     /locus_tag="L1V16_000591"
     CDS             complement(43407..44687)
                     /locus_tag="L1V16_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBN1274955.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(44828..45430)
                     /locus_tag="L1V16_000592"
     CDS             complement(44828..45430)
                     /locus_tag="L1V16_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBN1274956.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            45675..45881
                     /locus_tag="L1V16_000593"
     CDS             45675..45881
                     /locus_tag="L1V16_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1274957.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            46193..46912
                     /locus_tag="L1V16_000594"
     CDS             46193..46912
                     /locus_tag="L1V16_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBN1274958.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(46993..47676)
                     /locus_tag="L1V16_000595"
     CDS             complement(46993..47676)
                     /locus_tag="L1V16_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBN1274959.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            47895..50081
                     /locus_tag="L1V16_000596"
     CDS             47895..50081
                     /locus_tag="L1V16_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBN1274960.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT        16324 a         8899 c        10031 g        14970 t
ORIGIN      
        1 tgaatggtca aatacaagaa aaggtatttg gtcagtctcc aaaagtcata ttcttcatcg
       61 atcattaaca gacaaagaac tggcccgcca aggatatgag gacatctcct tgaagtacca
      121 gttcgtacac tcaacttatt gaaccgccgt atacgggtcc gtacgtacgg tggtgtgaga
      181 ggggcggaag gtcagttggc tttcccctct actcgatcgg atgtatttat cccttttgcc
      241 taagcacgta aaagcttgta tctatgataa ataaataaac atagcaaggt aaaccagcca
      301 atcaaagtaa gagaaagaat gaaatagaaa tagattggcg tttgataatg aagcgtgagc
      361 tcgttgattc ctttttgctg cttcacgatt ggggtcccga tatctgttac ttcataatca
      421 gtcaatgttt ttccattttg ctgtagcaca gtccgatcgt agacgataac agggatatga
      481 acagttttgt ccccagtgtt tttccacttg attgtcaaaa gaccgcctgg atgtgttttt
      541 ataaaagttg tttcgttttc tagtatttct tcgttatacc ggtcgtattt attgtctttt
      601 gtctccttat agattggcag atagtcaggt gtggtttttt ggaaaacgaa caagctggta
      661 gacatatctt tgctgaagaa tgttttcctt gcttcttccg gcgtatcgaa tagataagta
      721 tgtcgactga caaatgtttc attttcccac ttttccagat gctggtataa gttctggatc
      781 gtctgtgctg aaaaaataag aatgccaaat atacttaaaa gacggaacca cttttgttca
      841 gaccactggt tcagtgaaag ggcaaggtaa agtagaagca atagcgtaaa tggcacgaaa
      901 aatcgaaatg gaaactggat caaactaata aaaggcacat ttttttcgat caatgtcgtc
      961 catggaatca agctagtaga aagaaaaaag aaaacaagac ttgtgtacaa cacgattttt
     1021 tggaataagg tgttcttttg ttgaaagaaa ataaaaagca aaaaacctga taatatcaat
     1081 ataggaaagg ccttagggta atggagccaa taactgccat ccagatctat cgccttttga
     1141 ctcatttctc tgttaacaaa gggaggaaga atcttattcc cactgtaaac aatagctaat
     1201 cctgcccaaa tatttgctgt cagaacaaaa taaagcaaga ccgacttaat cagttgaagc
     1261 agtgcttttc ctttttcagt ctggttaaaa aagtaataaa gataaaaagg gatatacatc
     1321 aaagctaaca tgatcgaaga cagtaaatgg atctgtgtca taagtcccac tgagacagcg
     1381 actttgataa cagggaactt tttatgaagg acgaaatcag caatagggat catacataaa
     1441 ggataaaaac aagtccccca gctagtgaat ccttggttga tagaccagta ttgaatagaa
     1501 tacgtactca tgaataaaac ggctactggt acacttaccc aatttcgaac attgacatat
     1561 ctcagtaaaa tcagcataga aaatcctgaa ataagataaa gaatgaaatt tgaaagaatc
     1621 tgataatgaa accagctacc tgcaagcaac acgatcaatc cttgtaaata agcgaaaaat
     1681 gggccgtaaa cggcattcac gatcctgcca ctttgctgga atccataaag ggaaggaaaa
     1741 taatggaaat ccccatattt aatttgttgc gcggcatcat agaaccgatt gtaatggaat
     1801 ggggcatcag cacccaaaat tagtttatgt gtgaataaat gaggcatgag aaatgccaaa
     1861 gcaatgaaaa aaattgctaa aaatgggcca tattttttca attgtcgaac tcctttgcaa
     1921 actttagata aattcatcat atatcctatg cgagaggtag gcaagaaatt agaaaattca
     1981 tgaaaatatt tatgaatttt acaagaaaaa cataagtgaa agttctaagg agagaggatg
     2041 cgacataagt tttgttgcat ctccttgttt tgaaacagaa tttttcttaa tactcgaaac
     2101 aaagtagctt tttcatgacc tctcggtaaa cggtgttcaa tcagctgctt ctcggtaata
     2161 agctcactag cctagaaaat atgagaagct attttctgac tagcgctctt attactcaaa
     2221 gcataacgca gttttcacaa cctcttcctt aaacggtgtt caaaagcttg catctgcggt
     2281 aataagccca acccaacaaa aaatatgagt agctattttt ttgggctgta cttattactt
     2341 gatgcaggac agctttttca caacctcatc ggctttcatt ttctattttt ttcctgaacc
     2401 catataataa aagaaagaac aaaaaaactt gcaagggagg acacatgtga agcagagtaa
     2461 gcaaaaacag tctcgtcgac ttttgtttcg tttgttttta ttaatatgta tcgtcgtagg
     2521 gttactgatc gctttatatc cattttatgt ggattcttta aatagtttta ttgatcaaaa
     2581 acgtatcgaa caagtacaaa aacggaccgc agctgaaatt gaagtgcagc gaaagaaaat
     2641 ggaggagaaa aaccaacgat taactgacca aggattcaat cctggtactg atcctttcaa
     2701 tgaaaagaac agaaatgaaa gtacaacatc cagccaatta gaggaatggc tgatcggaag
     2761 tatcaatata cctaagatcc aattaaatat ttcactttat gatcggctca atggtaggat
     2821 ccttgaaaat ggagcaggcg tcttgcaagg aacctctttc ccgcttggtg gaaattcgac
     2881 gcattcagtg atctctgctc acagcggttt acctaatcga cggttattta ccgaattaga
     2941 tcgtttagaa aacggagaca cgtttatttt gactgttttg ggggagaaat tggcttatca
     3001 agttaaaaat atacaagtgg tactgccaga tgacacgtct gttctaacga tttcagaagg
     3061 agaagactta gttaccttgc ttacatgtac gccgtatatg atcaacacgc atcgtttgct
     3121 agtgacagga catcggattc cttataacga atcggtaaaa aaagaagaag gaaaaggaaa
     3181 tcaggaaaga accatgcggc aatggtttat tcttgcagga acgataatag ctgtagtcat
     3241 actgttagtg tttatcggac gactaatcta tcagtataga ttaagtaaaa aagtgcttga
     3301 tttttcattt attattagtg attcgtcagg gaaaccggta aatggtagtt cattcatttt
     3361 gaaacataag aaaaaaacac ttactagaaa tggtgtgccg ttttcagtac aaagcgacca
     3421 tcatgggaaa gtcaagctgg atcaattgcc tggtggaact tatcgaatcg tttcagctga
     3481 tgatcctaaa gttgctgttt cttttggtat tagaaaagta aaacaagaga agatatactt
     3541 ttttgagggg cgaaaacttg taaaagagct tcaaaaaaat ggtttttatt ttaaaatcaa
     3601 tgaataagta aggagagaaa aaatgatccg cacaacaaca aaattgtctg ccaaagaact
     3661 ggaatctgtt ctatcgattt ggctgcatgc taacttggat tctcatgaat tcattccatc
     3721 aacttattgg gagaatcaag tagaatctgt taggaaagct ttaccagatg cagtgattta
     3781 cttagcagaa atagatcaag aaattattgg ttttgctggg gtgattgatc agtttatcgc
     3841 aggaatcttt gtgaaaaggg aataccggca acaaagaatc ggtacgcaac taatgaaaaa
     3901 aataaaagaa accaataaaa cactgacttt gacagtctat caaaaaaatc aatcagctat
     3961 tcatttctat ctttcacaag gttttacaat tcaaacacag caaaaagatg aagcagtaaa
     4021 tgaggaggaa cttgtgatga aatggaatca aaacgctgat ttttgatgaa cagaataacg
     4081 aaataatgct cccagcctaa ttttttgctg ggagcattat ttcattttga agtcactaat
     4141 ttaactgtgt gaatatgcag ttgttacaat ctttgataaa cggtgttcaa tcagctgacc
     4201 ctcggtatta gctcaaaaaa cggcaaaata tgaggaacta tttttccatt tgtttctcta
     4261 atactcaggt caaaacgctg atttcacaac ctcttgataa acggtgttca aacggctgct
     4321 tctcggtaat aagcccacta gcctagaaaa tatgaaaagc tattttctaa ctagcgttct
     4381 tattactcaa agcataacgc tgatttcaca acctcttgat aaacggtgtt caatcagctg
     4441 accctcggta ttagctcaaa aaacggcaaa acatgaggaa ctatttttcc gtttctttct
     4501 ctaatactca ggtcagaacg ctgatttcac aacctctctt tcacaacctt attttactcg
     4561 tttataattt tcatcgaagt attttccgct acggatatca tctggcattc catcgtatgg
     4621 ttcttcgcta ataacatctt cattgtctat acctgcatca cccatataag tgatcgtagc
     4681 aaattcagga acaagtaatt ttggataagt ttcatatttt tcacgagctg cttccatttc
     4741 tgcgatatgt tcgttttgga aagtaacagt gatttctgga tgttcttcaa cccatttagg
     4801 gaaaaagatc attccgtgaa gtttcttttc atttggcata aagtccaatg ccacgtctgt
     4861 ccctgttggc tctgtccaag tgattttgaa tacgccgtcc gtcaatttaa cgatatcagc
     4921 ttcttggtct tttacccaac ggcctttgac cattccgcca tggatacggt aatcaacagt
     4981 atggtcattt ttggcatacc attcatattc ccaaccattg tcatacgtat agataaagtg
     5041 agttccaata aaatcttcca attctttaaa ttctttcatg tttaagcatc tccttataaa
     5101 ttaaaacatg taataaacta catgttttcg attactcatt tatgatagaa tggatttaaa
     5161 gatttgtcaa ggagggaaaa ctgatggcaa gaaaaaatac acttcgatat attttgttag
     5221 ggttattaag taagaagaag atgacaggat atgaattgaa tcaatcgttc aaaaatgaaa
     5281 taggagaatt ttggcaagca aaacatagtc agatttatcc tgaacttgca aaaatggaag
     5341 agcaaggaat cattcagcat caagtagaga tcacaggtga aaaattggaa aagaaagttt
     5401 atgaattaac agaagaaggg aaggaacaat tggcagagtg gattcataca cccaccaatg
     5461 aactaccggt taatcgagac gaatttgttc tgaaattgta tttcgtcaaa gacgtgaatg
     5521 atccggcatt agtagaaatt attcagcagc agcgtgacct tcatgaagaa aaacgacttc
     5581 atctattaga gcgaaaaaaa acgatctttc ctactgaaaa agaaaaacat gaaaattacg
     5641 gacactacct gattttagcg catgcgatca atcgggaaac agaatatgca aattggctaa
     5701 cagatgtatt agaagaaagt aaccgaaaaa aataaaaaaa tatccgaaca gtgatggaga
     5761 attcctttct atatgaaaga aacgcagatc accgttcgga tattcttatg ttcaaacagg
     5821 ccttttttca agtatttatg tagcatctac ttattaaaaa gcttggtact taggagatta
     5881 gtggcgttta gagttctttt aacaactgtt cgtagtcagc tttttcatcg acaggaagga
     5941 gcttgtaagt taattcgtct gtctcgttgt catgaatgat gtacatctta gcattctctt
     6001 ctttgaagtt accgatttgt aaaatcgtat agcgttcgtc gatcaattcg atatctttga
     6061 ttgcttttga aaaaacttta cggacatggt gcattttctt ttggcggatt tctgcctttt
     6121 ctgcagcttt tgacaaagta aatccgtcat ctaaatattt tttgatcagt tctactttta
     6181 tgactgtagg taaacgatat tttctaggac aattcgcatc agcttcgatc gaacgaatga
     6241 atcccttttg ttcccaatac cttaattgac gtggagacac acctacgata tcacttaatt
     6301 cactgatgcc aacaaccaat tgatcatttt ccaacaaacg tttaagggaa gccccaacca
     6361 tttttgtcac tccttttgtc ctcttgcttc ccttaattat atccgtatta acttatgtgt
     6421 caagtaggtt gacaaatagc gaatttagga ctaaagtatt ctagtagttt cagaaaaaat
     6481 tcagaaagaa ggagaaatat gagtaacaac caacccgtag atatttacgg aaaaccatat
     6541 aatcggacac ttttagttgt tgtcttatta attggtacat tttgtaccgt tttgaatcag
     6601 accttattga cgacagcttt tcctacattg atgaaagctt tcgatatttc agcgtctgat
     6661 gtgcaatggt taacgactgg tttcttgcta gtcaacggga tcatgatccc aataacagca
     6721 tggctgatca ataaattcag ttcaagaaat ttatatcttt ctgccatgac gatctttttg
     6781 atcggaacga ttacttgctt tacagcacct aattttagta cattactaat cggtcgtttg
     6841 atccaagctt gcggtgtggg agtatcgatg ccattattgc aaaatatcat gctatctatt
     6901 ttcccgccag aaaaaagagg atcagcaatg gggatgtcag ggatcgttat tggacttgct
     6961 cctgctttag gccctacatt atctggttat atcattgata actaccattg gcgtgacttg
     7021 tttggtatgg tactgccaat cgttgttctt gtcttggttt tagcattctt cctaatgaaa
     7081 agtgttattc cattgtcaaa tcctagcatt gatattttat ccgctatttt atcaacgatt
     7141 ggattcggta gtttacttta cggattttct agtgtaggag atgacggctg gggaagcttg
     7201 aaagtaattg gtttcttagt tgttggtgtg attttcatcg ccttgttctc atggcgtcaa
     7261 ttacatttgg aacatccatt cttggaactt cgtgtattca aatcatctac attcacgatt
     7321 gcagctgttt tagctggtgt aacaaatatg gcgatggtag gggcagaaat ggtcgtacca
     7381 ttgtatattc aaaatattcg tggagaatca gcattccatt ctggcttgat gttgttgccg
     7441 ggtgcattga tcatgggggc tatgatgcct gtgacgggtg cgattttcga taaatacggc
     7501 gcgaaacgtt tagccatcac agggatgttc attttgacag cggcaactgc accatttgct
     7561 ttcttgacaa aaacgactcc agttttatat atcgtgatcc tttatgcgat ccgtatgttt
     7621 gggatctcca tggtcatgat gccggtaacg acttctggta tgaatgcatt gccaaataac
     7681 ttgatcagtc atgggacagc ggtaaataat acattccgtc aaatcgcaag ctcgattggt
     7741 acagctattt tgatcagtgt gttgacgaat gtgacaaaag caaatatccc aagcaaatct
     7801 gtattggata atacgccatt agcttataaa gatcaggcaa tcaatgccac actgtcaggt
     7861 taccatgccg cgtttatcgt agcgatcatc tttgggattc ttggctttat tattgccttt
     7921 ttattgaaga aaaaagaacc tgttctaatg aaagcggggg ataatgcatg attattggag
     7981 ttttgattgt cagcttgctt gcttttgctt taacgaacgt gttcgctaaa aaaacatggc
     8041 aaaccttttt atctttgatt ttcggactaa tcttcgtcgc ttcactaagt ttgatcgtcg
     8101 ctaatttgtc caatcacttt ggaatggaaa aagtaacgga aacaaaaaca gaaaaaattg
     8161 tttccagtgc tgattcccaa ggagcagata tgcttttgta taaagcttta gggaatggaa
     8221 aagaaaaagt gtatctttac cgaacaaatg aaaaacaaga aaaaccaaaa gcaactggta
     8281 cggataacga aacaaataaa gtagaaaaga cagacggcga tgctgaaaaa gtgacgaaaa
     8341 ctacttattg ggaatacaaa aacgacatgt ataaattctg gttcaatatt gctgataaca
     8401 atcacgaata tgacagccga gtgaatacat tcaaaatccc agagacatgg gtagaattaa
     8461 gtacggacca agcagccaag ttagctgaat tagtgaagaa acagcaaagt acgatggaaa
     8521 gtgaagcaaa agcttatgtt caagacggta tggtaaaagc aatgactgaa aatccaaaaa
     8581 tgagcaaagc agagcaagaa caacgtacga aagccttagc tgctgaattc caacaacaag
     8641 cattcgcaaa attagtgaaa gaagcaaaag gcgaataata ttttgaacac catgtaggag
     8701 gttgtgaaaa agctgctctg catcaagcag taagaacaat cagataaaaa tagcactcca
     8761 tatttttcat ctgattgggc ttagtgccgt agatgcaagc ttttgaacac cgtttaagga
     8821 agaggttgtg agcctgccgt ttaactctga gtcacaagga gcaatttcaa aaaacagctt
     8881 ctcatgtttg ttgactattg tgacttgtga ccgaggagtt ggcaggagaa caccgtttat
     8941 tcgaaaaaag gaactgcgac aagacttttg tcacagttcc ttcttttttt tgctatgcta
     9001 tactagatgt aaaaaatagg agaaataaaa tgagggaaat ttattctttt gaatcaaaaa
     9061 tctatgcttc cgaagtcggc aagggcgggg catatattat ttttccgtat gatataagaa
     9121 aagaattcgg tgctggaaga gttaaagtcc aagcaacttt tgacaatgtg ccgtatgaag
     9181 gcagtatcgt gaatatgggc gtgaaaaatc cagatggttc agtctgctac atccttggac
     9241 tacgaaaaga tattcgtaaa aacatcggaa aagaaatcgg tgatattgta gcagttacag
     9301 tgaagcaaaa ataaaagagg ttgtgacaaa agacgtgtca caacctcttg ataaacggtg
     9361 ttcaaaagcc agtttctcgg tagtaagtca aatttatgca aaaatgtgga aacccatgtt
     9421 tacaaaattt ttcttactac tcgaaacgaa gcggctttat cacaacctct tgataaacgg
     9481 cgttcaatca gctgtccctc ggtattagct caaaaacggc aaaatatgag aagctatttt
     9541 tccatttttt tctctcatac tcaggtcata acgctgattt cacaacctct tctttcataa
     9601 tggtttttca ccatctttat aataaactgg ttatttgata tggaaatcta ttttttccaa
     9661 ccaatctaaa atcttgtaac ctaactcttc tgacatcgga aaagaggcgt tgatttgtgc
     9721 attggagata tggtcaacat ggataccgga agtgatcgta caacttcccg gaacggcagt
     9781 tttgatgatc acagctattt tttcggctaa gacatcgtct ttatggaacc gaccatcgtg
     9841 gctagggaaa cgtacagttt gcatctctgt atcacgagaa aatgtagtga ctgttccgat
     9901 atgtggtgta tctccgcctg ttaaagtgat caataagtct ttaccgatta ctttaacagc
     9961 agcttggatc gtgaaaccta gtttggttac ttcaactatc gtttcttttt ccatattaat
    10021 caccctgcca acgttttgaa tgctcattta caatttcaaa ttgatccaaa agtttcattg
    10081 tatggtgatt aacaagatct tggatcgttt gaggctgatt ataaaaagca ggaattggtg
    10141 gtatgatttg cacacctagt cgtgctaatt tagtcaagtt ttccaagtga atggcattta
    10201 atggcgtttc acgaggaaca atgactaact ttcgttgctc cttcattgtt acatcagcag
    10261 cacgtgcaat caggttgtcg cctaaaccaa cagagatacc tgcgactgtt ttcatacttg
    10321 ccggtacgat gatcattcca tcggtcaaaa atgatccgct ggcgacagca gcacctaaat
    10381 ctttgtttga ataatggtaa tcaaacaggc tttcgaattc agttagtgat aagtcggatt
    10441 ccagctttaa gttctgtttt gcccatggac tgatgattcc gtgtgtttct atcatcggat
    10501 attcttttag tttcttcact aggttgatgg cataaatggt gcctgaagcg ccacttacac
    10561 caatcacgat ttttttcttc cgttgtgcca attgttccat tttccgcact cctttttatg
    10621 atgtcaaaac agttgcagat cattcattat ttcaaatatt tttcccaatc ttctacttct
    10681 tggaattttg cacgtacaaa atgttctttc atatcgaaag gaactgtacc gtcaaagata
    10741 gtttttgcac ttatcccacg gaaacgaata gagccaggat tatattctgg taattctgat
    10801 gggtccaatg gatggttcct cattcctggg atcacgatga tatctttatc tccttggaaa
    10861 cgagtgttga aagtccaaac tacatcgttc atgtcgaaaa tatcaacatc ttcatcgact
    10921 aaaatgactg tcttcaattc tttgaaggct gataaagcaa gaatagctgc ttgacgctga
    10981 ataccttcat ccgcttcgtt ttctttacgg atttgcatga tggtcatcaa tttaccacca
    11041 cctgcaggag gattgtagac atttactact tttcctggaa tagctttatc gaccaaggca
    11101 agaatacttg cttctgtagg aataccggcc atagatacgt gttcttcact gggaccaatc
    11161 gttgtttgca tgattggatt gtcttttcgg tgagtaactg ctttgacttt cactacttgt
    11221 acagctggat tagcatcccc agtatagcca ggaaattctg gcattgcttt tcctgagttc
    11281 gtgttgatat cttcttgcat tgtttcattt ggcatgattt ctgcttcaat gatgaattca
    11341 gcacgagcaa tacccacttc atcgactgct ataccatcaa cgatttgaat aggttcgtta
    11401 cgcaaagctc ctgcacacca tagttcattg tagccaagtg gagtggtagg tggttcgaaa
    11461 gtcgtgccaa tggcaattgc tggatctaaa ccaatattga tagtgatagg cattggttta
    11521 ttcaaggctt cgaattgttt ttggaagtga ccaatgtggc gtccgccagg catgatgtac
    11581 ataccgatcg tatctttatc ttctagaacc atacgatgga tcgttacatc gctcattgtt
    11641 ttttctggat ctgatcctaa gactacaccc attgtgatgt atggaccagc atcttcagga
    11701 gtatttgtag gtgcaggcaa aatgttgcga atatcgaagt ctgcatcggt agctagatga
    11761 acgacttctt gtgctggagc gtctgctttg tctactttca caggtttgat tggattttct
    11821 acagcgtctt tcaagaaacg accaagtgtt cgataatcat ggtgcaaaat ttcacctaca
    11881 cgtttacgac tagccattgt tccgatgttc acacgtgtgc cggggaaacc tttgatattg
    11941 ttgaaagtca tagctggtcc ttcttgagtc ggacgtttta ctgtaccgcc agcaccgata
    12001 taacggtaaa caccagataa ttctgcttca ggatcgattt caatatctgt ttcgtgatat
    12061 tgacctggaa gtgtttttag ttcttcgatg acttttctta aatcatacgg ttgatctgtc
    12121 atgagagatt cctccttagt tgtctttacc tatctatagt aaaaggtgaa aaagaggaaa
    12181 acaattcaac ttgttcggta aagtattcta caatggaatg gatgcgtttt tttgataata
    12241 gaataaacta tgatatactt atcactaaaa gaaagcgcat acttagtgtt ggaggaagga
    12301 aagtgaaaaa aatggaggag tcatttccta aagcagtaaa agtggaaaat atagcgaata
    12361 ttttgaaagt tacatttgaa aacggagaag taaaatacgt gaaatctcat tggacagaag
    12421 agataaccga tgccttgcaa tttggaaaaa aaggaagagg aaaaagaaaa aatcttctcg
    12481 cactttctcg taatatgtgg attgggactg aagtaacgat tgaagcagat ggaacagtat
    12541 tcataaatgg aaaagacagg tatacgccag aagagttgtg gtacaaagga aagaaaagta
    12601 taccagaatt ataaaaaata attaaaaaaa acagcgcgaa acaaggaaca tattacttcc
    12661 tcgtttcttg ctgttttcta ctatttcagc gctcttatga ctcaaatcta aatgtggttg
    12721 tcacaacctt attctgcacg caaagcgata gcggcgtctt ttttcgctgc cattcgtgca
    12781 ggaagatgac cgccaagcat cgtcaatata gtagagacga tcactagaat aatcgcatgg
    12841 acaggattta gttgagcaac attttttaga tccgtcatgt tgtataagat gctattgata
    12901 gggaacgtag ctagccatgc aataaacaca cctaatatcc cagaagaaat acctaaaata
    12961 cacgtttctg cgtcaaatac gcgagtgatg tcttttttac gtgcacctaa agcttttagt
    13021 acaccgattt cttttgtccg ttcaatcaca gatgtataag taatgatact gatcatgatc
    13081 atacttgtta ctaaagagat ccctgcaaaa gcaataagga cataagtgat agcatccatc
    13141 aatccgccag tcagttcagt catcgttcca gctaaatcag tataaatgat tttatcttca
    13201 tctgatttgc ctttattgta atcatctaga taatccaaga tcttttcttt gtcttcaaaa
    13261 ttgttcggat aaatcatgat acttgaaggc aagctgtctc cacctaaata actaagcaat
    13321 gtttgtttgg cattttcgtc aactttttca gtagttaaga catttacacc actgtctctt
    13381 tgagctttga cgatttctga ttctttgttt tcgttgacga tttgagtcgt taattgatcg
    13441 ctataagcga ttcctggaga taagagattc attgtagaag aagatttcac gcgtaggatc
    13501 cccgagatct tcaattcatc agaagcattc tgatacatcg catcataatc tgtattaggg
    13561 ataaaattcc cagttggaag ttttgtatag taagtattgt tgtttactaa tttgaatgtt
    13621 gtaccaacga tatcatcaaa atcaagtttt tcgtcttctt tcacatcaaa tccaagattc
    13681 ttcaatgcgt tgatattagt attattattg ccgtctacga tcagcacgac atctgttgct
    13741 gaggctggat aacttccggc aagtaaagaa taattgtctt ttaaaaagtt ttctttgcta
    13801 gtgtcaagct gtgtagggaa acttgacact cccacacctg tcattgctga catcgtacta
    13861 gataaagaaa gagattccgt atcaggattt tgattcgaga agctgacagg ctgtactttg
    13921 ccatttacat cacgtaaaag attgattcct gtagtacggg taaatccgat attattactt
    13981 aagttaggat cgatgtctgt tacgtaatcg acgtatgttt gatcaatctt attcgtgtgc
    14041 tgtgctttat cttcttcgct gacttttgca gtaatcgttt tgctgtctgg ataatccgct
    14101 ttgcttgcac ccaatccggc atcgtcacga gtctggttag tcgttacctt agaaatagta
    14161 atcggaaatt tcgccatcgt ttcagcttgc gtgttatcga tttgtttttg gaatccagaa
    14221 gaaagggaca gaacgatcgc gattccgatg atcccaatac tggaagcaaa ggaggtcaag
    14281 aaagtacgtc ctttttttgt tcggatattg ttgaaggaaa gctttaacgc tgtccaaaaa
    14341 ctcatctttg ttctgcgtaa gttaaattga tcatcttttg gtcgttcgat gtgaggatgg
    14401 gaatctgtta agatcttacc atcagaaaat tcaatgattc gatctgcgta ttgatgggcc
    14461 agttcaggat tatgtgtgac catgatcact aatttttctt tcgataactc ttggatcaat
    14521 tccatgatct ggatacttgt ttctgtatct aacgctccgg ttggttcatc gcacaaaagg
    14581 atatctgggt cattggctag tgctcgagcg atggccactc gctgcatttg tccaccagat
    14641 aactgatttg gctttttatg catatgattt gtcaagccga ctcggtgcaa tgcatcttct
    14701 gcccgttttc gtttttcgtc tttagaaaca ccacttaatg tcatcccaag ttcaacgttt
    14761 tcaataatgc ctagatgacc aatcaagttg taactttgaa aaatgaaacc gatagagttg
    14821 tttcggtagg catcccagtc actgtcctta aagtctttag tagactttcc gttgattacc
    14881 atatcaccgg aatcataatt atctagtcca ccaatcacat tcagcatagt cgttttacca
    14941 gaaccactag gacctaaaat cgctacgaat tctttttgtc tgaaagcgac agacacacca
    15001 tccaatgctt tggtggtggt ttcgccgact ttataatatt tttttatatc ttttaattga
    15061 agcataatca cccttctccc gtattgaaat attcggtata ctaataagta tatcagaaca
    15121 atgatcgtag tatacgaaat aaatgttaac tgaagatgaa ctacaagaaa aaatctagaa
    15181 atttttcaaa aaacagaggg agatcaatga atcgtatttt agtagtagaa gatgatccgc
    15241 aattacagtt gctttaccgt tctgtgttgg aacgagcggg cttttcagtc atcaccgcat
    15301 tgaatggaga ggatgcgctg aaaaaactag aagcgacacg tatagaatta atcattacag
    15361 atatcatgat gccgaaaatg gatggctatg acttgctaga ctcattacgt agcaccagat
    15421 ttgacacacc tgttctaatg attacggcaa aggccgattt tgaggataag aaacgcgggt
    15481 tcaaattagg agcagatgat tatatgacaa aacccatcga tgtcaatgag atgatcctac
    15541 gtgtggaagc attgcttcga cgttcaaaga tcaattacag cagtagcttg ataatcggac
    15601 aaacaaaatt agagctagat gcttatacag tgttacaaga tcagcattcg ttgattctgc
    15661 ctcaaaaaga atttctgctt ctgtataaat tactgtctta tcccaacaag atcttcactc
    15721 gccaacagtt gatggatgat atttggggat tagatacgaa tacagaagaa cgaacgatcg
    15781 atgtacatat caaacgttta aggacccgtt ttgaaaagac ggaagatttt caaatcatca
    15841 cagtacgggg actaggctat aaggcggtta tttaaagatg aaaaaaaagc tattttcaca
    15901 attatggatc tattttgcta gtattgtctt catttcgatc ttagtgacac tgctgtgttt
    15961 tctcggtttt attttcttat tgtctcgaca ttctatctcg cctgctgaat cggctggaaa
    16021 accaacgtta tacccgttat tcgtctttgc ggggttcagt atggtcgtgg gtacaggaat
    16081 atcgattttt gttgggcggc gtatcctgca tccaatcagt gcgctaggga caaatatgag
    16141 tctggtagca acgggagatt tttcgattcg aatggatgaa cagcagaaag tagcagaagt
    16201 acagcaactg tataaagatt tcaacgttat ggtccaagaa ctcaatagta tcgagacact
    16261 gaggaatgac tttgtgtcca gtgtatccca tgaattcaaa acaccactag caacaatcca
    16321 aggatatgtt caattgttac aagccccaaa tctctctgac gaagaacgcc aaatattttt
    16381 atatcggatt atcgaaagta tcacgcagct ttcacaatta acagagaaca tcttaaaatt
    16441 gaacaaactg gaaaaccagc gtatccaact ggaaaagaaa gagtatcgat tagatgaaca
    16501 aatcagagaa gtaatcgttt tttttcagcc taaatgggag aaagaacagc tagaattgga
    16561 tatcgaactt gctgcagtaa attacacagg caatgaagag tttttgtacc aagtgtggct
    16621 gaatatcatg gataacgcca taaagtacaa tcaaatcaat ggacagattc atatcaaact
    16681 atttgagaca gccacagaga ttgtactgga agtgaccgat tcaggtgtag gaatgaatga
    16741 agagaccaga gatcgaatgt ttgaaaaatt ttatcaagga gatacaagtc gtcaaatttc
    16801 tgggaatggg ctaggacttt cactggttaa aaaaattcta gaactgcatg atggacgtat
    16861 tgattatagc agtatcgaag gagtaggaac gacagcaatg atacggttaa gtaaacaata
    16921 ggaaaaagaa taaaacccct aaaaattcta ttgaaggttt ttaggggttt ttagtcgttt
    16981 ttttgtgatt agggaaatgt tcttacggtt cttttggcat aaaaatcgct gctttcttat
    17041 tgaactacga gaaatgttag aggtgtcatt gaaacaagga catgatgcaa gaaagagagc
    17101 gaaagtcatg cgtcgctctc tttttttggg tggatagatg gacagaaaat gtagggctta
    17161 gttttcttct tgatttaaat actcccaaaa tgtatctgaa gccaaagaat gctcaccgac
    17221 tttacgagta aatgcaagat aactctctgt tgttggagaa atagggagaa tcacagtatt
    17281 ttcttttaat agattcttga ctgttttttc cataacaata gcaatcccca tgtcatttgc
    17341 aatcatattg atgatcaagt cgattcttgc tcctttataa gagatttttg gttcaaatcc
    17401 agcttcgcga cacagatcta gtacaggttg atacaagttc gtagtggggc caaggagcaa
    17461 aaagttctcc tttttcagtt cgcttagatc caatttcttt ttactagcta aaggatgatt
    17521 tttaggtaga actgctacaa aatcgtctgt ttcagtaggc aaccactcaa tcgaacttgg
    17581 tggggcctgg aaacttctag caaagtggat cgtgtcacta tgttcattgg cgtcattgta
    17641 agttaattcg acactttcca cttctttcaa ctggactgta aattcaggat ggcgtttcaa
    17701 aaactcggtg attttggaaa aacctttata attgatcatt gtcggtatcg ttaagatatt
    17761 taatgaaaga ttgttgtctt tcgtataggt ttcaagcact tcttgcatag catggtattg
    17821 ttctacgaca ttttttacat atgggagcaa taagcttcca gcttcggtca attcgatttt
    17881 tctatgggcg cgttcgaata atttgacgtc taattctgtt tctaacgaaa gaatctgttt
    17941 agaaatattt ccttgggtgg tgaattgtcg atcagcagtt ttggtgaaat tcattgtttc
    18001 ggctaaatca agaaaaactt cgaatttatg gatatccatc atattcctcc tacttattcc
    18061 aataaagaat actttaacac aaaaaatgaa ttggtgtaat cttctctgtc tgttacaatc
    18121 tttcttgcag cgaaagcaat aattacagaa atttttctga tttttttcgc ttcgtagaaa
    18181 aagagaggag ttttttgatg ccaactggag ttttgatcaa tgtaggttcc gttttgtttg
    18241 gcggactaat tggcggatta gtaggaaata aattaagtga acattttaaa gcacagctga
    18301 cgatggtttt tggtgtgtgt tcgatgggga tgggaatcta ttccattgcg ccgatgaaaa
    18361 atatgccggc tgttattttt gctttagtga taggaacagc gattggtttg attgttcatt
    18421 taggtaatgg gataaataag ggggctgcgc tgatgcaagt acctatttct aaaatcttcc
    18481 ctagtgaaaa gcttggtatg acccacgatg aatttatcag cacattagtg acggtcattg
    18541 ttctattttg tgcaagtggt acggggatct atggaagttt agattctggg atgacaggag
    18601 acagtacgat tttgatttct aaatctgtcc ttgatttttt cacagcagct atttttgcgt
    18661 gtaatttagg gtatgtcgtt tctgtgatag caattcccca attcattatt ttttatattt
    18721 tgttcttatt ggcaaaattt atttatccat tgactacacc agacatgatc ttagatttta
    18781 aagcttgcgg cggattcttg atggtcgcta ccggttttag aatgatcaac gtgaaaatgt
    18841 tcccagtagc tgacatgata cctgcaatga tcgttatcat gccactgagc tggatgtgga
    18901 caaattggat tatgccactg ttataataaa aatcaaagag aagccatttt ttgctgacta
    18961 aaaaggatca aatcttttag tcagtttttt tgtatttgac aaactgattt tgaaactata
    19021 ttatatgttg tataatatag attgaaataa aatattacac ttgagaatag aaggtgacgt
    19081 aatgcacatc cagattccaa ctgttcttct tgatggtact gtgctagcag cattaagcaa
    19141 ggaagatatg tatgggtatg ccttaacaaa aatcgtacaa gaaagtctct ctgtcagtga
    19201 atctacacta tatccggttt tgagaagatt gaaaaaagaa ggatatcttg agacctatga
    19261 tgaacctttt gaaggcagaa accgtcgata ttactcgttg acaccaatgg gaagtcgtca
    19321 tttagaagaa attattgatg aatggattgt ttttcgagat tctttagacc ggttattgga
    19381 ggagagcaca aatgaatgaa tatttgaatg aagttgtgga tcatcttcaa gaaattcctg
    19441 aagacgatcg ttttgatttg atccagtatt atgaggaata ttttttagat tctggaaaaa
    19501 cattagatca gatcattgat gaatatggta caccaaagca gtttgcctta aaattaaaaa
    19561 tcagttactt ttcagaagaa gaacaagcag aaaacgagtt agtgaaaaat ccaaaaagac
    19621 aaattcgcct gatttggtta atcattatcg gtttatttgc ttctcctgtc ctcattccac
    19681 tagcactggg gtttatattg gttattgggg gactattggt tgctttacta gcgctcattt
    19741 ttagtatcta tgttttatgt atcagtatct taggtgttgg cctattcatg atcatctcag
    19801 gaatcagtgt gtttggacaa tcgattctga gtggattatt ctttatcggt gtcggtctgt
    19861 tcgccacagg aagcgcagta tttatttcgc cactgttgct gaaaggaaca aaagggcttt
    19921 tttatgtcat gatgaacttt gttaaatgga tgggacgacg ttttattaca aaaagagatc
    19981 tgcattcagc gggcgtttga aggaggacac ataaattgag attgaaacat tttttgatta
    20041 ccggtattgg tctgatgctt actggtggcc tcctagcagg tgcaacttat acattaggcg
    20101 ctcaaaagag tctgacttgg gataatggtc ctcggttgat cgatatggtt actgagacaa
    20161 aaaaaatcaa ggatgcaaac aaaatcgtca tccatgcaga aaatcaaaca gtttcggtca
    20221 tacgcggatt ggattttgag ataaaaacga cttatgataa gacagaaaag ccagaaataa
    20281 aggagaaaaa tggcgtgttg actgtgaatg cagtcaaaaa atcaacaggt gcaatcatta
    20341 gtttagaaga cacaagtgca caaatcacta ttgttgtccc tgcagatcat gaattatctg
    20401 aattgacaat cgaagggaat aatagtgcaa ttgatatcaa cgaagtatca atcaaaaaag
    20461 tgaatactaa gacacatgat ggctgggtat cgttcaatga atttacagga ggaacaataa
    20521 ctgcgaaaga tgaattaggc tcacttcgat tagatgaggc caatgtggat aacttgatcg
    20581 tcacaggtga aaacagcaac ttccatctag aagacagttt gatcagcaaa gaaggaaaag
    20641 tcatcctaaa cggtggcaat ttatctttgc atgagatgga aaacagtggc tatactatcc
    20701 aaacgtctgg tgaatcttat attgaaaaag actaccagcc aataacaaat actttgttag
    20761 aacaaggaca gaaaaagcta aagatcactg ctaaagacac atcgatcaat attacgacgg
    20821 atcaagagga caatgaaaca gattgatcct gtactcaact ggatatttta agaaaaaaca
    20881 gcaaagatcc ttccaatctt tgctgttttt catcgcttaa cgcacataac tatagtaaaa
    20941 taagaaagaa aatatctaaa aagaaaacag ggtgaaagag tatatgaagg tagaagaagg
    21001 tcaaagagaa aagttaaaaa cagaaatgga aagattacat acttatatca ctcaactaag
    21061 ccaaaccttc tatgatccag acaaagaaaa agtgatggtt aattacccga acaattcaga
    21121 aggtcgccaa ttagagcaag tgtaccatga agttttcaaa catttattga cggtgaagaa
    21181 agagctggat tattattctt taccgattat cgatacagga atattgaagt atgatgggaa
    21241 gaaggaacga tttatcttta aatctgttcg ggaagatttg cctctttcag cagggatgga
    21301 tctagaggtc ttggtagaag actattttac agaagaaaag cactgggttc gaacaaaatt
    21361 ggattattta ccgcaggcag ccggagggac acaggcaagc ggttggtaca tcactgaaga
    21421 caaagagtta gaactagaag gtgtaatggc gcgtattcga aaaaaaaatt aaaaaagtaa
    21481 cattagatat ttattgaagg ataaaggagc gcaggaagta gcatgagaga aaaaagagca
    21541 ttttatatca atggttatgc agggattgtc ggattggtcg tattagcttt agttggattg
    21601 tttttcttct atttaggtat gtggcaagcg aaagtttggg cacttttttt aagtattttt
    21661 ctttggttga tcacgttatt gttgttaagt tcggcaactg tagtcagtcc taatcaagca
    21721 aaagtaattt tgttttttgg acaatattta ggtacgattc gagaaaatgg ctttttcctt
    21781 acgatacctt tggcacaaaa aatgactgtt tcgttgaaag ttcggaattt caatagttct
    21841 gttttaaaag tcaatgattt ggatggaaac cccatcgaaa tctcagcagt agtagtcttt
    21901 aaagtcgttg atacagcaaa ggcattattc gatgtagcgt attatcaaga ttttgtagaa
    21961 atccaaagtg agacagccat tcggcatatc gctagccaat acccgtatga tacattcaat
    22021 gagaatgatt tgacgcttcg aggaaacacg acggcagtgt ctgacgagtt gcaaaaagag
    22081 ctgcaagagc gtttagcagt agcaggtgtc gaagtaatcg aaacacgctt gaaccattta
    22141 gcctatgcaa cagaaatcgc tagtgccatg ctccaacgtc aacaagcaaa agccattttg
    22201 tctgctcgac aaaccattgt tgaaggagct gtcacaatca ctcaaatggc cttagagcaa
    22261 atcgaagatg gacaagaaat caatttcacc gatgatcgga aagtccaatt gatcaataat
    22321 ttacttgtct caatcattac agacaaagga acgcaacctg ttatcaatac aggcgacatg
    22381 aaagaccgta agtgacatac tttttgtaag ataggaagaa ggagtttagg acggattatt
    22441 gtcttgaact ctttttttag ttgttttaaa gaaaatgaca aaattgaaag aagaatgata
    22501 gttgattcga aggcagaatt gttcgctttt ttctataatc agtatataaa gtaagagaga
    22561 aggggaaaaa gtgaaaaaac ttctgatcgg tctacttgtt ttcatcgttg tggtacttgc
    22621 aggggtgaaa atcgcagatt acgtagttat gggtggagaa gaatactatg tacaaattac
    22681 gacagatggt acaaaaacag tttcaaaatc agactctgga caagaaacag tcaactatag
    22741 atatatcctg cctggctata cgaaagaggg taaggaaaaa gaactggact tcaagggaca
    22801 attgactcga ccgcttcgta aaggagcata tttaaaaatc acctggaaca aaaataaagg
    22861 tgtcacttcg tatgaagaag tcgaaaaaaa agacgtgccg aaaacagcac tggaaaaact
    22921 aattaaaggg tagggaaaga aatgaacaaa atagtcgaag tacagaatgt aacaaaagta
    22981 tacggaaaaa acaatgagaa aaagacgcaa gcattaagcg gcatcagctt cgatgtagaa
    23041 aaaggcgaat ttattgggat catgggcgct tctggttctg gtaagtcgac acttttgaat
    23101 attttatcca cattagataa accaacagat gggcatatcc gaatcaatca aaaagatgtg
    23161 accacattaa aaggaaatca actagcagat tttcgtgcga atgagattgg ctttattttc
    23221 caagatttca atttattaga aagcttgaca gcacaagaaa atatcgctgt tcctctttct
    23281 ttacaaggcg tcagaccaaa agaaatcaag caacgtgtcc aaaaaattgc agaacgttta
    23341 tccatctctc atattttgga aagctatcct tctgagattt ccggtggaca aaaacaacgg
    23401 gtcgccgccg cacgtgcatt gatcacacaa ccaacgattc tattagggga tgagcctaca
    23461 ggtgcgctgg attccaaaag tgcccgggat cttttagata cgatggacga attgaataca
    23521 aaagatcatg tatcgattct tcttgtgacg catgatccgt tttctgcaag ttattgccaa
    23581 cgtattttat tcatcaagga tggcggtatc catcaagaag tgaaacgtgg agatcaaagc
    23641 cgtgattcct tctatcgaga aatactatct attcttggaa acttggaaca gtagggggag
    23701 attgactatg ctttggaaat tatcacttac tgggatcaag agccgtttaa gagactactt
    23761 ggtgttattc tcaggattag ttatggcatc tgctattttt tacatgtttg aatcaatggc
    23821 aagcaacgaa gcttttttga aaagtaatac gatcgttgcg gctacagtta tcattttccg
    23881 attcggttct gttttactag ggatcatcac attcgtttat attttatatg caaattcctt
    23941 tttgatgacg atgcggcaaa aagactatgc aatgtttatg atgctgggag caaaaggcag
    24001 aaaaatcgca cagatgattt tttctgaaac attcttagta gggatcgcag ctactttagt
    24061 gggttcagct gtcggtgtag gattgacaag tatcgtccac cgattattag tggatcagtt
    24121 agatctcaat atttcgcatt ttacaccttt tagtattcac gggttgttga tcactgtttt
    24181 gttttttgct gttttgtttt tattagctgc tgttgtcaat gctttttcga ttgtcaaaaa
    24241 accgatttta gcattgattc gtgcggatca gacaccaaca agaatcaagc agcataaatt
    24301 cttgtttttc cttgaagtag tactgggaat tgcttttcta ggctgcggtt actatatgat
    24361 gaaacacgtg gggacctatc aagtctttgg tataggggta gccttagtta cgatcgtatt
    24421 aggaacttat ttcattttcc attctgtgat cattttcttt ttatcattac taaagaaatc
    24481 agaacagatt tcattgaaaa aattgaacaa tttcacattg tcacagttaa actttcgtat
    24541 tcgtgaatat acacaaatgc tctcaatggt cgctatgctg tttgccttgg cactgggcgc
    24601 tttgacggta ggattaggtt ttaaaaatga aattgcagac ttgacagaaa acaattctgg
    24661 atatgatcta gtgatgaata atcctcgggc agaagatcag caaaaaatca aagaactttc
    24721 accaacactt tctgcttctt atactcaaaa agaagatgcg ggaacgattt actataatgc
    24781 aagtgaattt gcggctcaac cattgatcat gataaaacat gaagatggaa caccgccgaa
    24841 gatcacgaaa gaaaaagttc ctgctaaaaa aatgaatgaa ctgactgtac aagaggaact
    24901 tcgaagctat gaattgccgg aacagcaaga aaaagaaatc aaggtagtca gtcaatcaga
    24961 atttgatcaa ctgaacttgc cacaatccac tttacagcta gttcaggtaa aagacttcca
    25021 agcaaacctg aaaccaatcg aaacacttgt tgctcaaaat aaaatgaaca atccatcttt
    25081 gcaaaaagta gagtacagca accagaaata tgaaatgtat gaagtgtata atggtctatt
    25141 ctctggtttt gaatttatgg gattcttcct aggtttagct ttcttgacca tgcttgctag
    25201 ctgtttgatg ttcaagatct tgtcaggaag caagagtgac attgctcgtt atgaaatgct
    25261 tgaaaagata ggaacacgac gcgggttgct taaacaatcg atccgtagag aagtaggcgt
    25321 gttattctta gcaccaggaa tcttaggtgt agtccatgtc ttattcggat tacaaatgtt
    25381 tggtctattc atgcaaaatc catacaaaga tatttgggtt ccgtttacga tattcttcgt
    25441 attgtatttc atctactatg tactgacgac atggttatat actggaatcg tattgaaaaa
    25501 gagattgtga aaaagctgtc ctgcatcaag taataagaac agccaagcaa aaatagctcc
    25561 tcatattttt cgtttggttg ggcttattac cgcagatgca agcttttgaa caccgtttgt
    25621 tcggaaaaag aggttgtgac aatatttttg tcacaacctt tttttcacgg tcttttatta
    25681 gaatatagta aattttttct cgttactcac ggaataagct gttaagaaaa cggtttccat
    25741 gtatactgga atcagtgcaa atgaaagaaa agagggtgca aggaacatgg aaatcaatga
    25801 acaaaatttt ggcgaaaact atcacttgat tacgatcacg aatcaaaatg ggacatcttt
    25861 gtctgtcagt gatcttgggg cacgggttgt tcattttcaa acaataatcg ataatgaaaa
    25921 acgagagttg atcttaggtt ttgatgaagc aaaagaatat ctagaaaaag acccttatat
    25981 cggtgcttca atcggacgta tggctggacg gattacgaat ggcacattca aattagatga
    26041 tgaaacgttc gaagtaaaaa cagacccgga cactggtcat tgtttacatg gtggtgcacc
    26101 tagctttgaa gccaagcagt ggcattatac agtcatcaat ggtgaaaacg aagcatcggt
    26161 cattttctat cagactagcc cagatatgga aaacggattt cctggaactt tagatgtaga
    26221 agtacggtat acgctgacga acgatgatac atggcgagtg acggtccaag ggatcagtga
    26281 ccgcaaaaca gtattcaatc ctacaaatca tgtctatttc aatttaaccg gtgatccagc
    26341 acagtcaatc gacgaacata tactttggtt gaatagccga ttatttgcta cgctcaataa
    26401 agatacaacg cctacaggag aagtagtttc agtaagtggc acagcatttg acttccaacg
    26461 tcctaaaaaa ttaggtgagg tctttgccag tgattttcgc caatcaatga tagtgggcgg
    26521 catcgatcat ccatttttgt tgaaaaaaca atctggttta ctaaatgctg cggaattgac
    26581 aagcccagat gaaaaagtat cgatccaagt aaaaacagat gcttcaggaa tcgtgatttt
    26641 tacagcaaat tttggagaag atggaccgga aatgcgcggg aataaattag taaatcatgg
    26701 cggtatcaca tttgagactc aagaactgcc aggagcggag cgacttgaaa gttttggaga
    26761 tgtcactctg gaacctaacc aagtacgcga gtttgtaacg gaatacaaaa taaatataaa
    26821 gaaatagaat aaattaaaaa gggagtgtga cagtgtcaca tccccttttt aatttattct
    26881 atttctttaa aggcagatca agccagaatg atttgtctaa acttaacaag gttagtacag
    26941 gaacagttgc agctttaact gtacgagtag ttgtttctgg tatctgtctt gccgtaaaat
    27001 tgttccacaa atcccagatt gaagcgacac ggaagatgga agaagcgttg ttgacgcgtt
    27061 ttatcgttga aaattctaat cctgtgattg gcacgccatc tgttgtccat ttgattggca
    27121 catcgaatcg cttagacata ttgaggattt cagcgtttgc ttcttcagtt gttgctgctt
    27181 cttttttcgg ttcatcatat tttgtcaggt cgtacgcttc gatgatcgcg ttcaattttt
    27241 gtgaatattg gcgatctgta gcataacgtc cttccaaata tttggttgct tctttgtagt
    27301 cttttgtttc cgacttccaa gttggtttgt agaaatcagg attgccagtc agtccatttt
    27361 tgatcaagtc ggcatagtct tccaaacttt ccttgtaaga aggatattta cggaattgtg
    27421 cgcggatttg gtagctttgt ccggaactat cttgttcaag tgtattgaag gtcacgctgc
    27481 ttcctttata tgatcctttg ataccaaaaa ggttatgatt tggttcgctt gataataagc
    27541 tgtttccaga tccactttca aggatagctt gagccatcat gactgatgcg tagattcctt
    27601 ctttttgccc gatttcctgt gcatcatctg caatcttttt caagaactga tcagttgttt
    27661 ggttttgact gaaatggaac gagccatcta atccatctaa aatagatgag ccgcctgtca
    27721 gcgaacctga agcagcaggt aaacctgcta agtttactcg gacagcaaaa tcaggcgtga
    27781 aatctgaaat agaagttact cgaactttat ctcctggttg aggcgcatgg ataaattgtc
    27841 cgttcccaat atagatacct acatggtgag taacaccgga agaaggtccc cagaagacga
    27901 ggtcgccagg ttgggcctga cttactggaa tctgcgtacc tgcatattgc tgttcgcctg
    27961 tccagccacc gatataatga ccggttgctt tcatatatac gtaataagtc aaaccagaac
    28021 agtcaaaagt atttggacct tttgctcccc atacatatgg ttttccaaga tgcttgaatg
    28081 cttctcgaac gattgcttgt tggacattcg ttgtatttgt aggcaataca gcatcaattg
    28141 gtgattttac aacaaaatca gaagaagcag aagatggatt ctctataccg ctttgatttg
    28201 ctgtatttgg acgagatgaa gcattgttcg ttccgccatt cgatgaacca ttgtttggat
    28261 ggtttggttc tctctgagta tttccattgt tattcgatcc agatgggttt gtttgattcg
    28321 aagaattccc gctgttcgaa ttattgttat tattgtttga attatttgaa ccattattat
    28381 tgttgttatt acccacatct ggtttgtttg gcgtttccgg atctggtgta ctagggactt
    28441 cttcactagg atcagttggt ttctctgttg aagtatccgg tccagcttta aattctgcag
    28501 taatagataa attgttcgta cctactgtaa aggtctttgc atcataattt acttctttgg
    28561 caccattaac agcgactgaa gcaatttgtt caccttcagc tggcgtaata gtgtaagtta
    28621 ccttcgtttc cgctaataaa ccttctaccg ttccactttc cgtaatatcc aaaggttgct
    28681 gttcagggga atccgctgtc gaagcagtca gttggatctt accaatcaaa gaaggagcaa
    28741 ttgtaaggga atatgtctcg gctggctttt cattttctga tggatcagcc ggatcaattt
    28801 cagttggctc ggtcgatcct gttgttgagt tagttgttcc agttgggtct tctgtaaaag
    28861 aatccgttgt ttcactagta gctgagctgg atgtagtcgt atctgttgtg actgtttgat
    28921 cagctatttg attatctacg gcaaatacgg tattggtcga caaaacagac ggagcaatca
    28981 gccaagtagc agctagcaaa cgtatcgttt ttttattttt cataataaac tagtcctttt
    29041 cctttcattg attttctgtc ttattcagca ttcattagac attttttgga acagataatc
    29101 gtgtcgaaaa gctttttctt ttcataaatc tgtctgtgta ttctaaataa aacaatttgt
    29161 aaataagcaa cgagcattca ttcgtttttc tttgacgttc attttattgc atagaccacc
    29221 tttgtttggg gataaacaag tggggataaa aatggttatg catatgtaaa ttataccaaa
    29281 gtttggaaag tatcacaaaa atttataaaa ataatgatcc taaaaagaaa aagactgaaa
    29341 tatgtgataa acatctcata cttcagtctt tttcattaac tattcataag acattaggtc
    29401 ttcatcaaac ccgctaacga gagtagtgat cattgctacg actagactaa cagccagtcc
    29461 tgctaagtac cagaaaaaag taccggaaat gaatgcaggc aatgtggtca gactaccaaa
    29521 tacaaaagcg atcgctttca cttgggcaaa tcccattaca gctccaccag cagctgcacc
    29581 aatgcaagca gcaacaaatg gttttttcaa tgggatcgca attccgtaaa cagttggttc
    29641 ggtcactccc gcaagtaaaa tcgaagcaaa agcagaaccg gagatcgaac gggtttttga
    29701 acgtttactt cgcagaaata cacctaaagc tgcaccagcc attccaaaat tggctgctcc
    29761 tgtcaacgga acgattcggt cgaacccata agcagagata ttactgatca tgacagggtt
    29821 tacagcccat tggataccaa atattaccaa aatattccaa ccaccagcga tgattgcgcc
    29881 actgatcggt ccgttaatat ccatcatcca agtaattgcg gcagctaaac cttcgccaag
    29941 gtaaacaccc gcaggcccga ataccattaa cgtcaaagga accgtgataa ctaatgaaag
    30001 taaaggtaca aatactaatt gcatattttc gcgaatatat tttttgagga atttttcaac
    30061 aaaagaataa aagaaaatac ctaaaatcgc cggcatgaca gtagacgtat actgcatcag
    30121 tactacagga atccccagaa aatcagtagc tgctttgcca ctgtctgaaa gtaaagaggt
    30181 cagattcggt tcaatcagtg ctgcagcaat gacagccgca atatatccat tcactttaaa
    30241 cgttttggca gcagaaaaag caagaaagat tggcagaaaa taaaagacgg cattcgacgc
    30301 agcagacaaa atatgataag ttccgcttgt ttcactaagc cagccaatcg tagtcgctaa
    30361 aacaaccaga ccttttaata taccagaacc ggcaaacagc ggaatgatcg gcgtaaagat
    30421 ttccgatatc aaaccaaata gtttttcgat cggatttagc ttttctttcg gagctgaatg
    30481 atcgatttga cgcgtcaatt ccttgtaagc aggagccaat ccctgatcca tgattatttc
    30541 tgcatatcta tcgagtaaaa tgaaatactt aatggaaggg atttgctgtt ttaatttttc
    30601 tgcattggct actggctgtt ttttcaattt gatacgaagc cgagtcgcac atggaaggac
    30661 agaatcaata ttgtcttttc ctcccaactg ttcaatcagc atatgaatct gctcggacag
    30721 taccatctgt tcaggattca ttgtcgtttc cattagaaga ccactccact cactaatata
    30781 atattggcgt aaggtgtcat ttcgcctgta cgaataaatg catgacagtt attcaactct
    30841 tttttcattt cttcatgtgg gataaagcta atcggtgtat ctggtaacaa taatttgatt
    30901 ttttccaata tttccgggtt cattgtcttt atttcttccg ccaattcaat cgattgtacc
    30961 tcaagttctt ctaaaacgtt ttctaaaaca gataaaaaac ttggaagacc gtttgagaca
    31021 gccaaatcta ttttttcagt accaaagggg acaggcatgc ctgcatcccc gatacttaat
    31081 ttatcaaagt gccccatttg tgcgattact cgtgaaatat ctgaattgat tacttttcct
    31141 tttttcatgt ttgtttcttc ctctcattgt taattttaga ctgctgattg ttctaaagct
    31201 tcgcggtaag ggatagaagg ttgcgcacca taagactgca cagcaacaga agaggctaga
    31261 tttccataaa ggatcgcttc tttcaagtta ctaaggtctg gctgaagtgt gctgcttaat
    31321 gcgccaataa atgtatcacc tgcggctgtt gtgtcaacgg catccacttt aaaagcaggg
    31381 acgataccgt gttctttttc tgtatgatag aaagcgccgg cactgcctag tgtaatgatt
    31441 actgttccaa tacctaattc atggagtttt tcggctgctg cgaccaaact gttatgatct
    31501 gtcactctga ttcctgtaat gatttctgtt tctgtttcat ttggtataat gatatctgtc
    31561 ttttcaagta gttcagtagg aatcgtttca cgagctggtg caggattcag gatcgttgtt
    31621 tttcctgcgt cttttgcaat agaaaaagct aggatcgtcg catctaagct actttcaaac
    31681 tgagcaataa taaagtcact gtttgtaatc agttgcttgt tttttaggac ttcttgttca
    31741 tggaaagcat tatttgcccc tgcatggatc aagatactat tttctcctgc tgcgtctacc
    31801 ataatcattg cttgtccggt tgtggcgcct tggatttcag ctatcccaga tgtatcgatg
    31861 ttttcttttg tcagtagatc taataactgt tgtccttcgc tgtcagcccc aacgcctcca
    31921 ataaaagatg tccgtgcgcc tgaacgtttg gctgccactg cttggttggc acctttacct
    31981 ccgccagcgt gaaaaatctc atgcgcatgc atcgtttcgc ctggcttggg catgttggtt
    32041 aaacgaaggg tagtgtccat attaatactt ccaattactg taaccgtgtt cattttacaa
    32101 acctccaact atctcattta ttttgatggg aaaattattt tttaaaacgt tttagtaaaa
    32161 cgttttaata gttcgataaa aatatagcac accttgaaag ctatttcaag ggtgcagttg
    32221 aaaatctttt ttctaatcgt acaggtaatc ttttttcttc ccattctttt tctgggaatt
    32281 ggatccgatc taacaataac ttggcagatg tttgtcccaa ttcgaagatt ggttgtgcga
    32341 tcgttgtcag tttcggcttg atatactcgc acatatctat attatcatag ccaataatgc
    32401 tgtagtcttc agggatgctt tttccagctt cctctaatcc gcgatataat ccaaaagcta
    32461 attcatcatt taaagcaaac acaccagttg cagcagaatc aagaagttct gctgtgatct
    32521 ggtagccacc ttgttttgag aactgtgtag gtaagaggat cagttggtcg tgagggattt
    32581 ggtaaacatc aagagcagat ttaaacccct caatccgagc gtggacattt tccggtggat
    32641 tttcaggata gacaagggcg atcgtttgat gtcctagact aagcaagtgc atgcccgcta
    32701 ggtaaccacc gcgaaaatcg tctgttcgta cggcatcact aaatccttca gattttttct
    32761 gatccaaaac aatgaagggc cggccttgtt ttttcaaatt ttcgttgatt gcatctgtag
    32821 agacagcaga agtcgcgata atgaatccat ccacacctcg acgtgtgagc tcggctagat
    32881 attcgatttc tttttgatga tcagaatcag cattacataa tatcgtgacg aaattctgct
    32941 tatacaagat atcctcaatt cctcgcatca gtgtactgaa gaatggattc gtgatatcag
    33001 gaacgagtac accaattgtt ttcgtttcct tggtaatcat ttgtctagca aaatagtcag
    33061 gctgatagcc taattcttct ttggcagcta aaactttctg aacagttttc ggactgaatt
    33121 tctccgtatt tccatttaat atcaaggaga cagttgtgat tgaaacgccg gaaagtttag
    33181 cgacttcttt gattgtgatc ttttttttca ccatgttcat actcctatct aaatcctgtg
    33241 gttattttcc catgaaatca aaaagaagta aatgaaaatc acgtgtgcca gtacttattt
    33301 gctttgttgg atagcttcga ttatttgttt cgttgagcgt actcgtgcag ttttcggaaa
    33361 tatctttttt atgaacaatt gatgggattc tttgtcacga tcactgcaag catcttcagc
    33421 aagcacgata tggtacccgt gttgaaaggc atctaatgca gtagcatata caccgtttgt
    33481 tgtcgctaca ccgcttaaaa tgatagtttc gattccacgc cggcgaagtt gaagatcaag
    33541 agaagtacca aaaaaagcac ttggattgta ttttgtgata gtcaacatat tatctgtatc
    33601 tttcaaagaa tccttcaaaa gtaaatcagt gaattctgga ggtacagaag cagtcattcc
    33661 acccatatca gtttgttgac tcaaataagg gaaagtggag atgtctacgt tcactaaaac
    33721 tttcaaggca gcggtacgtt tcaatgttct tactaacaaa tcattgtttg tcagaataga
    33781 tgctgcagtg tgtggagaga gtgtaccgtt atttacgatc tctttttgca tgtcgatcgc
    33841 gacaaaagca gtttttgata aatcaaaaat catattttcc tttaaatcat tcatgatgtt
    33901 ccttctttca aataacaatg ttttttatgt aagtaaatca taaatcgttt atttgtcaac
    33961 taaattaaag gattcctttc tttagtctag agaaattcag tggtaaaata aataagtgtg
    34021 agaaaacgca ttcgatgcat agatatagcg agaaatatcg tgaaaatgga ggaatcagag
    34081 tgaagtatgt cgaagtaaaa aatgaataca aacgatacaa aatgggagaa acgaccatta
    34141 cagcaaatga cgatatttct ttttcaattg aaaaaggcga attagtgatt atacttggtc
    34201 caagtggagc aggaaagtca acgattctta atattttagg tgggatggat acacctgatg
    34261 aaggtcagat cattattgat gacacagata ttgcgcaatt ttcagataaa cagcttactg
    34321 cttaccgacg aacagatgta gggttcgttt tccaattcta caatctcgtt cctaatctaa
    34381 cagcaaaaga aaatgtggaa ttggcaacgg aagtttctcc tgatgcgctt gatcctgtag
    34441 aggtattgag gcaagtgggc ctagctcatc gattgaataa ctttccgtcc caattatcag
    34501 gaggcgaaca gcagagggtt tcaattgctc gtgcactagc taaaaatccc aaacttcttt
    34561 tatgtgatga accgacaggc gcgctggatt ttgaaacggg caagcaagta ttgaaattat
    34621 tgcaaaacgc tagcagacaa cacggcaata ccgttttgat cattacacat aattctgctt
    34681 tagcgcccat cgctgataga gtcattcaca ttaatgatgc taaagtaagg tctgttgaat
    34741 taaatgatca tccttcatcc attgatgaga ttgtatggta gggggatttt atgaaaacaa
    34801 gaacatatct taaagcaggt tttcgcgaaa ttcggcaatc taaaggacga ttcattgcaa
    34861 tcatccttat tgtcatgcta ggaacacttt tatttgtagg tgtcaaaact gctggacctg
    34921 tcatgcaaaa aacgatggat cactatgttg gtacagcagg actttctgat ttgcaaatcg
    34981 tttctactgg tggcttgaca caaaaagata ttgctcaagc agaaaagatc ccagatgcaa
    35041 aagtagaaac aggaaaacag atctattatt ccaatactgg caaaaacgaa gtgattcaaa
    35101 tattttctta taacaaaaat aacaagcaga acaagctaca attaactgat ggaaaactcc
    35161 cggaaaaacc aaaccagctt gtattggatg aaaaagcgga agatgaaggg tataaaatcg
    35221 gtgatattta tcagattgat tcagatgaat tgaaagaaaa agagtatacc atcacgggct
    35281 ttgtccgttc tccattgttc atcaacaatt tggagagagg atacgcgaac gtcggaaatg
    35341 gtagcgtcga ttattttgtc tatttacctg aatccgtttt taaaacagat atttattctg
    35401 tcttatatct tgattttaca aacgtaaaga atttgaatac gtacagcaaa gcttacaaag
    35461 ataaaatgga gcaaaatcaa gaaaaggcag aaaagtattt acaagatcga cccgaagaac
    35521 gcttagaaga gctgaaaaaa tcggccaacg aagaattaga accggcacag caaaaaatag
    35581 cggatggcaa agcacaaaca acgcaagcaa gaacacggtt agaagatgct aaaaaacagt
    35641 tagcgcaaca gtcagcaact atccagcagc ttcctgaagc gcaacgaaca atcgctgttc
    35701 aaacattatc tcaacaagaa gctcaacttg ctgaacaaga aaggcaatta gttgagaaag
    35761 aacgtgaact ggcctctgca gaggaagaat tgaatcgaaa tgcagaaaaa attgaaaatt
    35821 taactaaacc atcataccta tacaatgaac gttcagaaaa tgtcggtttt caagaatttg
    35881 gtgatctgtc tgatcgtatc gctgcgattg ccaatgtttt tcctgttttc tttttcttta
    35941 ttgccgcatt gatcaccttt acgacaatga cacgtatggt agaagaaaac cgcagggaaa
    36001 tcgggacatt aaaggcgtta ggttatacga aagttgaaat cgcaaaaaaa tatgcaatct
    36061 atgcaagtct agcctcaggg ataggtattg ttttaggaac gatattagga acgaatcttt
    36121 tgccaaggat catttttgag ctgtctaacg agcggtatga tattgggagt gcgcttattt
    36181 tttatgactg gccgccgatt ttacaagcag ctgccgcatt cttcattgcc gcatttggcg
    36241 ctgcaatgat cgttttattc aaagatttaa gagaacggcc tgctgcattg cttcaaccga
    36301 aagcaccgaa gccagggaaa cgcatttttc ttgaatacat cactccgctg tggtcacgcc
    36361 ttagctttaa tcaaaaaatc agttaccgaa atctcttccg atataagtca agaatgctta
    36421 tggcgattat cggaattgct ggatgtgccg ggctgatggt tgcaggcgtg ggattgaaag
    36481 attctctaag ttctgtttca gccaaacaat ttggaccgat cattgactat caagcaatcg
    36541 ttacattgga ttcatccacg gaagatagtc gtcaaaaagc agcggatatg ctgcagaagc
    36601 aagaaaaagt aaatgagatc ctagctattc atactcaaac cgtagaattg agaaaaaaag
    36661 gacatgcttc gcaaagtctg acagtgatcg taccaagtaa aacagctgat ttggatcgtt
    36721 ttatccattt aactgatctt gaagagaacc cacgctcctt gcctaaaaca ggaatcgcta
    36781 ttacgcaaaa agtagcagaa ctatttgact tatctacagg agatcatatt tcgctttatg
    36841 atgaagatca aaaagaatgg aaagtcgaag taaaagaaat cgtgaaaaac tatctaggta
    36901 gctttattta tatgtcccct gaatattatg cttcagttac tgatcaatcg atgatggata
    36961 atgcattttt gctgcgtaca gataagatga caacaaaaga agaagaaatg ctttccgaga
    37021 aactgcttgc cacagacgct gtgacaaata cgtctttcat gtccaaacaa atcgaaacgc
    37081 aagaagaatc aatggcgaac ttagactcgg ttgtcttaat ctttgtcgta ttatcaggac
    37141 tgctggcttt tatcgtcttg tataatctaa ctaatatcaa tatttccgag cgtgtacgcg
    37201 aattatctac aataaaagtc cttggatttt ttgataaaga agtcacgatg tacattgttc
    37261 gagaaaatat catctttact cttttaggaa tcatcggagg atttggtgta ggatatatat
    37321 tgactgactt catcttgcaa caagcgtcta tggagaatgt catctttcca ttagtgatca
    37381 catggtgggc ttatgtctta tcagcaggat taactatcgt atttacggtt attgtgatga
    37441 ttgttaccca tttcaaatta aagcatatcg atatgattga tgcgttgaaa tcgaatgaat
    37501 aaaaacagag gttgtgaaat cagcggtttg acctgagtat tagagaaaca aacggcaaaa
    37561 tagtttttca tattttgccg ttttttgagc taataccgaa ggacagctga ttgaacacca
    37621 tgaatcagag gttgtaaaaa agccgtcctg catcgagcaa aaagaatact caaataaaat
    37681 tagctcctca tgttttacat ttgagaagac tgattgccgt agataaaagc ttttgaacac
    37741 catttataga agaaacaaga atattttgct attttaaaca agaggataga caaatacatg
    37801 tctgatctct tgttttttat tgggcaacag acctcttaga atgtataaag ataaatttta
    37861 caaacgcttt cggttcagtt ataataataa atgataactt gtatatataa gttgtggtag
    37921 gtaataaatc agttgaatgg aggtaaatat ccatgacatt taaagacaaa gtcatttacc
    37981 aaatctatcc caaatcttac aaagacagta atggtgatgg aattggagat ttaaaaggaa
    38041 tcaaagaaaa actcccgtat ctgaatgatc taggcatcga catgatttgg ctaaacccta
    38101 tttatccaag ccctcaaaaa gacaacggtt atgatatctc tgattacaca gccatcgatc
    38161 ctatctttgg tacgatggag gaattcgaac agctaatagc cgaagcaaag aaataccgga
    38221 tagaaatcat gctcgatatg gtgctgaatc acgtttcgac agaacatgaa tggttcaaaa
    38281 aagcactagc aggggaccag cattatcagg acttcttcat tttaagagaa gagccaacgg
    38341 attgggtatc aaaatttggt ggaagtgctt ggtcgccatt tggagatacg gggaaatatt
    38401 atttgcactt atatgatcgg acacaagctg acttgaactg gcggaaccaa gcagtaagag
    38461 aggaactatt caaagttgtt cgtttttgga tggaaaaagg ggtaaaagga ttccgtttcg
    38521 atgttatcaa tgttatcggt aaagacgaac aattgaaaaa taataaagaa aatgatggca
    38581 aacctgaata tacggacaaa ccaatcaccc atacgtatct aaaagaattg aaccaagcaa
    38641 cgtttgggac ggattccact atcatcacag tcggtgaaat gagctctacg acgatcgaaa
    38701 attgtatctt gtatacagaa cctagtagag aagaattatc aatggtcttt aatttccatc
    38761 atttgaaagt cgattatgaa aatgggaata aatggtctac tcctccattt gattttgcag
    38821 aattaaagcg actatttcat acatggggag aaaagatgag tgagggtaac ggctggaatg
    38881 ctctattttt taataatcat gatcagccac gtgcgctcaa tcgatttgta gctatcgatc
    38941 agtatcgaaa acaaggagca gagatgctag caaccatgat ccatttgaac cgtgggacgc
    39001 cctatattta tatgggagaa gaaatcggca tgatcgaccc agactattca tcgatttccg
    39061 actatattga cgtagaaagt ttgaatgctt ataagttact ccttgaacaa ggattcacag
    39121 aaaaagaagc gtttcgtcgg atcaaagcaa aatctcgcga taactctcga acacccatgc
    39181 aatggtcaga cacagaacaa gcaggattta ctacagggaa accttggtta aaagttggag
    39241 gcaagctaga agagattaat gtagaaaaag aactatcttc tgaagattct attttgtcct
    39301 attacaagaa attgattcgg ctgagaaaaa catatccaat cgttgcacaa ggagattatc
    39361 atgcttatga agcaaatcat ccggaagttt atggctttct tcgccaattt gaaggacagc
    39421 agctgcttgt attaacaaat ttctatgata aagatacaag gatcgccatc ccagaaggat
    39481 tcacagaagc caatattctt atcgataatt attccgatac tgttcttcat caaagtctgg
    39541 agctaaaacc ataccaggca attgctttgc tgaaaaatta aaacaaaaac acaaaacgtc
    39601 gttcctacga gctattctcg taagatcgac gttttgtgtt ttatttaaaa taatcttctt
    39661 cagaaaatga agagttttca tactctcctt tatcgccata aaatttattg tagcgttgtt
    39721 tgaatttacg gaaaataaaa gtaacgagta atttgactaa cgtatagata ggaataccaa
    39781 aaataacgcc cacaattccc attagatcac ccatgacaag taaaacgatt aagatcgtaa
    39841 tcggatggat ctgtaaacga tcacccatta ctcgaggaat caccaagtca ccgtggagaa
    39901 gttgtacggc aaaccagaca atgacaaatt tgacagccat aaaagtagag tcttggaatg
    39961 caatgatcaa acctggaaag aaggcgataa acggcccaat atatggaatg atacataaca
    40021 acccagcaga aatagctaaa acactagcaa attctaatcc gatcagtaag aaacaaaccc
    40081 agtagactgc tccaaggata aatgaagcaa tgatttgccc ctttagaaat gaacccaatt
    40141 gttgattagc aatctttgtc aaatttttaa aatctgtacg aaatgctggt gggacaatcg
    40201 ctaaaactga ctgataaaat ttttgaggat ctctcaaaag gaaaaaagcg acaattggac
    40261 cagtaaataa agtaataaaa atagctgtaa cagttgaaaa aatgttgctg atccgttgtg
    40321 cgccactttc ccaataattt ccaataaatc cagctatatc agacgtcacg tcgtcaatag
    40381 aagcgaaaaa ttgattaaat gaatcggcaa aaggtgtttt ctccaaaaat tgtcggagac
    40441 tctcttgaaa atcttgaaac aaatctggca aactactgat caatgtcttt gcctgttctt
    40501 caagaaaagg aataagccat atgcttccaa gccccaataa aaataaaata atcacataaa
    40561 cgataatgac tgacaagttc ctcgaaaggt gcttgctcaa acgtttgatg actggttcca
    40621 aaagataata caagatcagt gcaaacaata atgggggcaa gatagtagcg ataatgattc
    40681 cgacaggctt gaatataaac gagatctgat ggaaaaaata aatgatcagc gcaagtaaga
    40741 taactattcc taaaacatag taagaggttt ttcctcctaa aaagcggatc aaacgattcg
    40801 ttgtatctgt ttcttttttc actctttttc ctcctttatc tataacttca ttatagacaa
    40861 aagcgggtat aaaaggaaaa tgatagaggt tgattgcaaa aatatcgtca atcattcata
    40921 taaactttct catcaattaa aataagaaaa cgcttgacag ttcttttaac catatgataa
    40981 attaaatcct gttgctaaaa cgtaactatt acggtttgcg aaaagcgaat cggaacattc
    41041 aaatgaaaga agatgagaag aggagtgtca taaatgaaac gattgatagg tatattggcc
    41101 atgctggttt tagcaggtat gttaactgct tgcggggcaa gtgggaaagc cgaggacagt
    41161 aaagaaaaat tgagcgtgat gacgaccttt tatcccatgt atgattttac aaaagcaatc
    41221 gtcggggatg aaggagaagt agagttattg attccagcag ggactgattc ccacgattat
    41281 gaaccttctg ctaaagacat ggcaaagatc caagatacag atatctttgt ttataatgat
    41341 gaaaacatgg aaacatgggt ccccgcaatc caaaaaacat tacaagaagg caatgtccat
    41401 acgataaaag cgacagaagg tatgctttta cttccgggaa gtgaagaagg acatgatcat
    41461 gaccatgaac acggggaaga aggccataca catgagctag acccacatgt atggctagct
    41521 ccaagtttag caatcaagca ggtagcaaac atacgtgatc agctgattga agcttaccca
    41581 gaaaaacagg aagtatggac aaaaaatgca gcagcctata ccgagaaact tcaagcactc
    41641 catcagcttt atcaagaaac ctttaagcaa gcaaaacaaa gatcttttgt cacgcaacat
    41701 gctgcattca actatctagc gttagaatat ggattgaatc aagtatcgat tgctggtctt
    41761 tcttctagtg aagaaccgtc tgcggcgaga attgctgaac tgaaacactt tgttaaagaa
    41821 catggaatca actatattta ttttgaagaa aacgccaaag atagtattgc cagaacgtta
    41881 gcaaacgaag caggtgtatc tttagaagta ttgaatcctt tggaaggatt gacgaatgaa
    41941 caaatagaaa atggagaaaa ctatctttct atcatggaag caaacctcga agcgttgaaa
    42001 aaaacgacag agacagaaaa cccgctagaa gatactttga cccccaaaaa agaaaagagc
    42061 gtctacaacg gttattttga agacgaggat gtacaagatc gctctctttc agattgggca
    42121 ggaacttggc aaacagtaga tacgtatgta gaagatggga cttttgatcc tgtttttgaa
    42181 tataaagaaa aattgaatca ggataagaca gcacaagaat ataaagaata ttatacgaag
    42241 ggctatcaaa cagatattgc ttcaatcaag atcagtgaga aagagatggc atttacgttt
    42301 aagaatggaa caacgaaacg ttcaaattat cgttatgtag ggaaagaaat cttgacctac
    42361 gaggcaggaa accgtggcgt aaggtatcta ttcgaagcag aagataagga aagtggcgct
    42421 tttagatata ttcaattcag tgatcacacg attgcaccgg ctgactccga acattttcat
    42481 ttatatgcag gaaatgaaag tcaagaagta ttgctgaaag aaatggagaa ttggccaaca
    42541 ttttatccag atacaatgga tggacgtgaa attgcacagg aaatgctttt gcactgatag
    42601 gcaaaaaaga accgaagggt ttggatcggc tggtcattta gtcggtccaa actattcggt
    42661 tctttttatg aaatcaattt ctttaatcca cggatagagg ctgggatggt ctcgccgttt
    42721 gccaacgtga cttctctggt ttttttatta atcgaccgca cattttgtgt attgataaca
    42781 taggatttat gacaacggat aaaattccga tgcattttct cgatttcttt gatcttctca
    42841 tagaattgta attgggcatg agtcaaatgg acttccagtt tatgtggcgc tcctagcgaa
    42901 gtagaaaaat attggatgtc tttgatcggt aaaaatttga tctcatcatt aaactctatt
    42961 ttgaagatat ctttttggat ttgggacatt tgaaaatctt cgaaaatttt gctcaggata
    43021 tgctcgacat tttcttttaa atcataaaga tcttctttga cgatataatc agtcggttcg
    43081 atgttgcttt ttaagatttt catcgacatt tccgtatggg aagtcacata gattattttt
    43141 cctaaaggat ctaattcacg gatcaattta ccgatcgcta caccatccat ttcactgtct
    43201 tctagttcga tatctaaaaa gtaaatacca aaagaagaag ttctgatctt ggctgcattg
    43261 agaagttctt ccggatcaga ggtagaaata tggacataac tgtctaagtt ttcaatcatg
    43321 attctatttt tgatcaccgt tgataaaact tctaattgtt ttggatcgtc ttcacaaata
    43381 taaatgggaa tcatatcatt actcctttat tttatttgta tataaatcgt ttgagaaaaa
    43441 cgctggtttt caattgatgt ttcaaggaaa agataaggat tggtctttgt caattcatcc
    43501 aagataaaca agccaaggcc ttcgtttttt ggatttgttt ttgttgagaa ccctttttgt
    43561 ttcaactggt ttaacggtaa tgtatttgtt gttgtattga tcacacgaat catcacggaa
    43621 tgattcttct tgagtatggt caattcgatt tttttcttct ttgcagcact agctccttca
    43681 atcgcattgt ccaagataat accaagcata cgtacaaggt ttaccgtatg tttcgtatcc
    43741 agttcgattg gctcaggaaa atgaagctgg acgatcaacc ctttttcctg tgccatcatg
    43801 agttttaatg acagtaaact acggatctca ggaactttca tattatccaa catacttaga
    43861 ttggccggaa aaaggttcat catctggcgt gtaggtaata tcgtttgatc ataataagac
    43921 cgtaatcctt ctaagtcgcc ttctgaaata tagctgtgaa gagaaaaaag cagattttgg
    43981 taatcatgtt tgaattctct caagtcttga tagttttttt ctagatcttt gatataatcc
    44041 tgttgcatcc tgacttgttg ctctaataac tgatcagcta atttcttatt agagattttc
    44101 caataataaa ccaagatgat caggccaaca cacagatata gaatgaaaaa actcgtattc
    44161 aaagctaaga catcaggtgt ttcaccagaa aaacgggtat aaaaaataat gatatagtat
    44221 gtaaataata tcaatgtccc gatcgtaccg atcatacggc ggtccacagt gtgaaaccaa
    44281 gtctctaacg atttttttaa acaaaaagct aataaagcag ataaaaaagc ggataagaca
    44341 atgtgaaaat actgcaatga atctcctggt tcaataaccg aagatttcaa aacaaaaaaa
    44401 tcgccgatgc ttgttaagtg atctcctaaa agcgacgtca ataacccaaa aggaagcgcg
    44461 taaaccaatt gttgacgcga agtcgaaaag aagaaaaaag taagcatcag cattcctata
    44521 gcaattagag cagtaaaaat ccctaaaatc gaatagaccc atccaatcaa aatacaagaa
    44581 atcagaatga ctcccgcaaa cagatatttg tatcggatgt gatggtcaat caataagata
    44641 caaattgtgt aaatcaaata ttgcaacgct atggaccata aaaacataaa gtacagctcc
    44701 cattgatttt taccaaatta tagcacaatt ggcgtattat ttttttaatt tttcagggat
    44761 tttgaattca gaactcatac caaagcagca gccagataca aaaaagtcag ataagttagt
    44821 taattgttta atgattgttt ttttcatgaa agattcctcc aaaattcatc aagtagtttg
    44881 taataggaag caacgtagct atttctaaaa caatcccaag tagcaaatag gtagaaaagt
    44941 aagaagctga gaaaaataac gtaatgagag aaaaaattag aaacatgctg atcgccttct
    45001 ttaataatgg gggacgtttc tcgggttcaa tgggattgat tgctgtacct cttgatccat
    45061 agcgaagcag taacaaaaag cagctgatta acaaaaagac catcattggg aaggagatag
    45121 tcaattgcag atgtttcatc accaagggaa cgccccataa ataaagtagt gtccacagca
    45181 gacaaacgaa ttcagagtcg gaatgcaatc cataagcata tctgcggatg cagatataag
    45241 aaagaaaggt gattcctgtt tccgcccatg agcctgtcac cagagaaaag actagaacga
    45301 ccgctagttt tccaagatta ttcaataaaa cttctaagac aaattttact tggacataca
    45361 ccatatcttc ttccgatttg tctccgctga ataaggcttc taataatttg ttcacaactt
    45421 tatctttcat ctcatacgta cctccaccac aaattttatg ctaaaaaaaa taaaaaacgt
    45481 cttttgtttc ataaaaagtg gttttgacat caaaaccgtc atgatctcct aaaaaaatct
    45541 tcgttttcca agaaccttac caaaaaaagt gacagttttg atacgaaaag tactttttat
    45601 gacaagtttg tgctttttcg agtgatttat gttaaaaaat tactgacctt ataaaaggtg
    45661 atggagggat tcttatggaa aatgaacaat tgtttgaagt cggcgaaaca tatgcattta
    45721 aatctgattt atttgaatca ccaataaaag gaaaaataga aaaaatctat gaaaatagtg
    45781 tgatgatacg tgtcatgaaa tgcgcagtag aagacaatga taccgctcat aatctgcact
    45841 ggcagttagt tgtacgcaaa tcaagtacaa tagaagaata aaaacagata aaatgttgag
    45901 agcataaaga ggttgtgagt ctcccgttta gctctgagtt acaaggaata atgttaaaaa
    45961 acagcttttc atgttttatg aatattgcct tgtgaccgag gtgttggcag gagaatactg
    46021 tttatttgaa aaaagggctg cgacaagact tttgtcacag cctttatttt catgaatagg
    46081 agttactttt ggctactttt agagaagtag cttttaagga gcagataaag tcaaggcttt
    46141 tatttctata aatgaagtag taaaatgaag aacagatttt attacaggaa ggatgccgat
    46201 aattgtgatc attgttgcag gaacgatcgg tgcagggaaa agcacactaa ctgaaatgct
    46261 tgcccaagat ttagaaacaa aaccttttta tgagaacgtg gaagataatg aagtattgcc
    46321 gctattttat tctaatccag aaaagtatac ttttttatta cagattttct ttttgaacaa
    46381 acgctttttg gcaatcaaag atgctttcag ccatgatgac aacgtactag accgctccat
    46441 ctacgaagat agtatgctgt ttcatttgaa tgcagattta gggcgtgttt ctgaagtaga
    46501 agtaaagcag tatgaaggtc ttttagaaac gatgctgaag gagttagaag aaatttcgcc
    46561 acaaaagaaa ccagatctac tggtttatat tcgtgtatcc tttgaaacta tgttagcgag
    46621 aatcaaaaaa agaggccggg aatatgaaca gctagaacaa gatcctgaac tctattccta
    46681 ctataaagaa ctcaatcgac gatacgaaga gtggtatgaa cagtttgata tatgtcccaa
    46741 aatagtgatc gatggggaca aatatgattt cgtagccgat ccggcatgtg gagaacaaat
    46801 cgtacaagaa atcaagatgc gggcaaagaa aatgacagaa gaggcagatg cccagtcgat
    46861 ccgctacact acaaataacc cgaaagcaaa gggaatcttt acaactaaat aatataaaaa
    46921 ctaagcaaat tgctcactcg cagatatttc tctgtgagca gcatcttgct tagttttttt
    46981 gattcattga gatcaaatag tgaaccgatt cgtatgataa aattgccata aatgaaatgt
    47041 ctgagtgagg gccatgatca aaaataaaat ggaaacgatc aaaatcgaat gggcgccaaa
    47101 cagatgatga cagaaaacaa ggacaatagc tcctgcgata aaggcaagaa cgacacttag
    47161 atagtggaaa aatcgatcaa aatctgcttt ttctttagaa atacaataat catataagtt
    47221 cgttgctacc ccttttaaat ttccagttgt aaataaatta gtgtaggcac gcccgttgat
    47281 tttatcaaaa gctacccact ggatcgatgc agtaaaagca atcaaaatcg ttactaatgc
    47341 gggatgctca tggacgggtg tcaaactaac aaagaaaaaa atcactgctt cataatatag
    47401 aacaaacaag cgccagaaat gtttttcttt ttttctaaaa taatcaatta gatactttgt
    47461 tagaagaatc cctaagaaaa agaaaagggt agacaatact tttttaccaa cacttagcca
    47521 ttctccgtca aatgcttgga tgatcgatag aatgatattg ccagtttgag cagaggcaaa
    47581 agcaccatat tggatataag tataactgtc catggctcct ccgataaatg tcagcaaaag
    47641 tcctattgta cgcccctcgt gaaaggaagt ctgcattttt ttcatcacct tttatgaata
    47701 tttttgtctt ccttatctta gcataaacga ttgaaaaaaa aggaaaaatt ttcagaaaac
    47761 taaaatcata tcgcttccca ttttcatttt tagaaaggtc tgttagtata aagaaaaaat
    47821 agacaacgaa actttaaata accaacttga aataaacaaa ttcaaagaag aaagatggga
    47881 aggaaatcaa tcagttgaat gaaaaagaaa ttctccgatt acaaaaagaa ttgaaacgct
    47941 gggagaacaa gtataaaaag cttcaacaag tctttcggct acaagaagaa atcattgcta
    48001 cctatgaagc ggcttatggc gaagcacccg gacttattga ggaagaagta caagtaaaag
    48061 aaagtgaagg aaacagctct ttctttaaaa tgatggagaa acgttcctat aatcgcttca
    48121 atcaagaaca aaaagcagct atcacatatg atatgaagaa acatcttcga atcatagcag
    48181 gagctgggag cggcaaaacg caaacaatct gtgcaaaagc tgtttatctg atgacgcaaa
    48241 aacaagtaga cgaagaacgc atactaatga tcacttttac aaggaacgct gcaaatgaac
    48301 taaaaaaacg agtagataat ttcagccaga gaaaaaccgc tgtccatatc ggaacattcc
    48361 atagtatctt ttttaggata tacaatgaaa tttgtcgaaa atttcctgaa gtagcaatgc
    48421 aaggaataca aggagacttt tcaaaggata ctgcacaaaa agtgaatgct gttttgcaac
    48481 agctgatacg taaatataat ctttatatat ttgatcaata tggagaaaaa acgattgctt
    48541 ctcggttaga ctattggcag aatatgaacc tttcagtaga agaaatggtt cagttagtta
    48601 aagaaaaata tgattccatt gataagaatg cacgacagcc gatatcagaa cgactgtatg
    48661 gattgctcac ggaactccaa gaacaaaaaa gaagccagca attgctagag ttcaatgatg
    48721 tactccaaaa tctgaaaagc gctttggaga atgaggagat ccagcattat atcggccaaa
    48781 aatatgatta tctattcatt gatgaatttc aagatactaa tccacttcaa tgggaaatcg
    48841 tgaaacggat gacaaaggaa aacaggatca agttgattgt tgttggagat gatgatcaga
    48901 gtatctatgg attcagagga tcagagccag catacatcaa gaactttgaa aaagaatatc
    48961 ctaccaaaac tcttttctta ttaactaatt atcgttctcg ggcagctatt gtccaaggag
    49021 caaatagatt gatcagctat aataaaaatg atcggatacc aaaggcgatg attccagcac
    49081 aaaaagaagc aggtgttatg gaagcctatt tgttttctga tactaaagca gaaagtcagt
    49141 ggctaatcaa acaaattcag acatttattc aaaaaaatgg gaaatataag gaatcaatca
    49201 tattataccg atcagcttca caaacgcagc agcttgtcca atctctgctg aaaacgaata
    49261 ttccttttgt actggaagca gatagtccat atgaaggtat ctttggtatc aagtctttcc
    49321 aacatttcta tcaaaaaatt gttcattggc aaacagcact gaatctgcaa aagaaaaatc
    49381 aggcctacca gcaattgctc cggcagctga tggcagactg ctacctgaaa aaaagtgaat
    49441 gcgatcaata cttttctcct aaatatcaaa atatagccgt tgcagattat attttgtcga
    49501 taagccccaa tttaaaatcg aaatctgcag aaatccgaga gtttgaggaa gcgttgcgta
    49561 aaacagacca gcatcaagaa atctattcgc ttgttcaaag ctatcttcat ctgccacgta
    49621 tagctaagga aatcgaccag agtgatcaag aatggatacg agaagaagta aagcagcatg
    49681 ctactttcag aagactccaa gccttatcgc aagaaaccca agcgacagct aaagaattaa
    49741 aaacccgctt gattgcttac agacaaggaa aacttgatgc actatgtatc cagagcattc
    49801 acaaaagtaa aggtcttagt taccgaaatg tctttttgat tggttgtaac gaaggaagtt
    49861 tgccttataa cggagcgaca gaaaagaaag taatcgactt taatgaaata aaagcagaac
    49921 cagtaacgac gatagaagaa gaacgaagac tattttatgt tgcgatgact agagcaagaa
    49981 atcgtctgta tctatgtgta cctcaaatga aaaattcaag aaaattgaaa gtatcgagat
    50041 ttatcaaaga aaccgggagt cgtgtgaaaa aaggaaagtg atagaagaga gggtgtgaca
    50101 gaagtggtca gtttcaagaa agaagaagga atgtacgaaa attgcttctc aaatttttgt
    50161 gaaatttcag cttattttcg aagaagctat ttctggaaca cagtttattc ggaaaaggga
    50221 ggtg
//
LOCUS       DAFLWQ010000010        49892 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.011, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000010 DAFLWQ010000000
VERSION     DAFLWQ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49892
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.011"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..87)
                     /locus_tag="L1V16_000597"
     CDS             complement(<1..87)
                     /locus_tag="L1V16_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBN1274961.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILE"
     gene            complement(89..286)
                     /locus_tag="L1V16_000598"
     CDS             complement(89..286)
                     /locus_tag="L1V16_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HBN1274962.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(680..2407)
                     /locus_tag="L1V16_000599"
     CDS             complement(680..2407)
                     /locus_tag="L1V16_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HBN1274963.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2400..3593)
                     /locus_tag="L1V16_000600"
     CDS             complement(2400..3593)
                     /locus_tag="L1V16_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HBN1274964.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(3780..4424)
                     /locus_tag="L1V16_000601"
     CDS             complement(3780..4424)
                     /locus_tag="L1V16_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1274965.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4518..4652)
                     /locus_tag="L1V16_000602"
     CDS             complement(4518..4652)
                     /locus_tag="L1V16_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBN1274966.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4654..6786)
                     /gene="feoB"
                     /locus_tag="L1V16_000603"
     CDS             complement(4654..6786)
                     /gene="feoB"
                     /locus_tag="L1V16_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBN1274967.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(6783..7256)
                     /locus_tag="L1V16_000604"
     CDS             complement(6783..7256)
                     /locus_tag="L1V16_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBN1274968.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7657..7881
                     /gene="nrdH"
                     /locus_tag="L1V16_000605"
     CDS             7657..7881
                     /gene="nrdH"
                     /locus_tag="L1V16_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBN1274969.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8040..10199
                     /gene="nrdE"
                     /locus_tag="L1V16_000606"
     CDS             8040..10199
                     /gene="nrdE"
                     /locus_tag="L1V16_000606"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBN1274970.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10249..11214
                     /gene="nrdF"
                     /locus_tag="L1V16_000607"
     CDS             10249..11214
                     /gene="nrdF"
                     /locus_tag="L1V16_000607"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBN1274971.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11303..12442)
                     /locus_tag="L1V16_000608"
     CDS             complement(11303..12442)
                     /locus_tag="L1V16_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1274972.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(12751..13464)
                     /locus_tag="L1V16_000609"
     CDS             complement(12751..13464)
                     /locus_tag="L1V16_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBN1274973.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(13718..14419)
                     /gene="nagB"
                     /locus_tag="L1V16_000610"
     CDS             complement(13718..14419)
                     /gene="nagB"
                     /locus_tag="L1V16_000610"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBN1274974.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14653..16185
                     /locus_tag="L1V16_000611"
     CDS             14653..16185
                     /locus_tag="L1V16_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBN1274975.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16376..17578)
                     /locus_tag="L1V16_000612"
     CDS             complement(16376..17578)
                     /locus_tag="L1V16_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1274976.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(17660..18349)
                     /locus_tag="L1V16_000613"
     CDS             complement(17660..18349)
                     /locus_tag="L1V16_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBN1274977.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(18455..18823)
                     /gene="rplL"
                     /locus_tag="L1V16_000614"
     CDS             complement(18455..18823)
                     /gene="rplL"
                     /locus_tag="L1V16_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBN1274978.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(18876..19379)
                     /locus_tag="L1V16_000615"
     CDS             complement(18876..19379)
                     /locus_tag="L1V16_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBN1274979.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(19583..19710)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(19789..20478)
                     /gene="rplA"
                     /locus_tag="L1V16_000616"
     CDS             complement(19789..20478)
                     /gene="rplA"
                     /locus_tag="L1V16_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBN1274980.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(20582..21004)
                     /gene="rplK"
                     /locus_tag="L1V16_000617"
     CDS             complement(20582..21004)
                     /gene="rplK"
                     /locus_tag="L1V16_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBN1274981.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            21347..22015
                     /gene="sdaAB"
                     /locus_tag="L1V16_000618"
     CDS             21347..22015
                     /gene="sdaAB"
                     /locus_tag="L1V16_000618"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HBN1274982.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            22028..22900
                     /gene="sdaAA"
                     /locus_tag="L1V16_000619"
     CDS             22028..22900
                     /gene="sdaAA"
                     /locus_tag="L1V16_000619"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HBN1274983.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(22991..24010)
                     /locus_tag="L1V16_000620"
     CDS             complement(22991..24010)
                     /locus_tag="L1V16_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBN1274984.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(24183..25088)
                     /locus_tag="L1V16_000621"
     CDS             complement(24183..25088)
                     /locus_tag="L1V16_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBN1274985.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(25147..25692)
                     /gene="nusG"
                     /locus_tag="L1V16_000622"
     CDS             complement(25147..25692)
                     /gene="nusG"
                     /locus_tag="L1V16_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBN1274986.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(25793..25963)
                     /gene="secE"
                     /locus_tag="L1V16_000623"
     CDS             complement(25793..25963)
                     /gene="secE"
                     /locus_tag="L1V16_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBN1274987.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(25987..26139)
                     /gene="rpmG"
                     /locus_tag="L1V16_000624"
     CDS             complement(25987..26139)
                     /gene="rpmG"
                     /locus_tag="L1V16_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBN1274988.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            26301..26945
                     /locus_tag="L1V16_000625"
     CDS             26301..26945
                     /locus_tag="L1V16_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBN1274989.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(27001..27504)
                     /locus_tag="L1V16_000626"
     CDS             complement(27001..27504)
                     /locus_tag="L1V16_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBN1274990.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(27517..27563)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            28101..29066
                     /locus_tag="L1V16_000627"
     CDS             28101..29066
                     /locus_tag="L1V16_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBN1274991.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(29165..30337)
                     /locus_tag="L1V16_000628"
     CDS             complement(29165..30337)
                     /locus_tag="L1V16_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1274992.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(30324..31469)
                     /locus_tag="L1V16_000629"
     CDS             complement(30324..31469)
                     /locus_tag="L1V16_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1274993.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(31483..32407)
                     /locus_tag="L1V16_000630"
                     /pseudo
     CDS             complement(31483..32407)
                     /locus_tag="L1V16_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            32524..33603
                     /locus_tag="L1V16_000631"
     CDS             32524..33603
                     /locus_tag="L1V16_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBN1274994.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            33635..34228
                     /locus_tag="L1V16_000632"
     CDS             33635..34228
                     /locus_tag="L1V16_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1274995.1"
                     /translation="MTKSLQTILESTKEIRVLGIGHCAKDALVLYETHRPDVLLTDIR
                     MPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYLIKQNLQAIIPSV
                     KSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKEVAAGKNNKEIAD
                     ALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(34338..34565)
                     /locus_tag="L1V16_000633"
     CDS             complement(34338..34565)
                     /locus_tag="L1V16_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBN1274996.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(34668..37256)
                     /locus_tag="L1V16_000634"
     CDS             complement(34668..37256)
                     /locus_tag="L1V16_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBN1274997.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(37276..37935)
                     /locus_tag="L1V16_000635"
     CDS             complement(37276..37935)
                     /locus_tag="L1V16_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBN1274998.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(37984..38487)
                     /gene="trmL"
                     /locus_tag="L1V16_000636"
     CDS             complement(37984..38487)
                     /gene="trmL"
                     /locus_tag="L1V16_000636"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBN1274999.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(38708..39574)
                     /locus_tag="L1V16_000637"
     CDS             complement(38708..39574)
                     /locus_tag="L1V16_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBN1275000.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            39683..40324
                     /locus_tag="L1V16_000638"
     CDS             39683..40324
                     /locus_tag="L1V16_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBN1275001.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(40386..41747)
                     /gene="mgtE"
                     /locus_tag="L1V16_000639"
     CDS             complement(40386..41747)
                     /gene="mgtE"
                     /locus_tag="L1V16_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBN1275002.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(41765..42664)
                     /locus_tag="L1V16_000640"
     CDS             complement(41765..42664)
                     /locus_tag="L1V16_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBN1275003.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(42666..43463)
                     /locus_tag="L1V16_000641"
     CDS             complement(42666..43463)
                     /locus_tag="L1V16_000641"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HBN1275004.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(43441..44145)
                     /locus_tag="L1V16_000642"
     CDS             complement(43441..44145)
                     /locus_tag="L1V16_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBN1275005.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            44276..44851
                     /locus_tag="L1V16_000643"
     CDS             44276..44851
                     /locus_tag="L1V16_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HBN1275006.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            44969..45646
                     /locus_tag="L1V16_000644"
     CDS             44969..45646
                     /locus_tag="L1V16_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBN1275007.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYAYDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(45725..47533)
                     /gene="pepF"
                     /locus_tag="L1V16_000645"
     CDS             complement(45725..47533)
                     /gene="pepF"
                     /locus_tag="L1V16_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBN1275008.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSDAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(47709..48707)
                     /locus_tag="L1V16_000646"
     CDS             complement(47709..48707)
                     /locus_tag="L1V16_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HBN1275009.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(48933..49586)
                     /locus_tag="L1V16_000647"
     CDS             complement(48933..49586)
                     /locus_tag="L1V16_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HBN1275010.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT        14934 a        10473 c         8762 g        15723 t
ORIGIN      
        1 ctcaagaata tcagaatatt taggatcttt acttatagat atatcattat ataattcatg
       61 aacaatttgc ttagcatttt ttttcatttt agcacttccc tggaattgct ccacctaaaa
      121 aaccacctat agacattcct gcaatacaag tagttgcctt ggcccaatcg accgtacatt
      181 tatttttagt gcaatacact ccatttccat aatattttcc actatgagtg gtacccccat
      241 agataagttg tgtctcttta atagacaaaa tttttaaatg tttcataatc taatcacccc
      301 taaattaatg tttttagact attattctaa cattcattaa atttcaaaaa acaattcctt
      361 cttgaaacgt agcaaaataa ttcctgaata agaatttaat cacttttaag tatataaact
      421 atgtatattc tttaatattt tttgagaatg cacttcgtac ataataaact ttaatcacat
      481 tagtctttca tacctacgat cgatctcttt gactcgcacc cataaattca taatagtttg
      541 tcggcgtctt tggacgtttc gaagatgagc tacgcattct ctttttttat agacaaaaaa
      601 gatagagacg aacatggagc ttccaaattt ggatatttga tccaattttg gaagctccat
      661 ttatttcgtg tctgtctttt tattttttcc agctttcgac taattcttgg ttctctttga
      721 tccagtcttt tgctgcttgc tgtggatctt ttccattgtt gatttccaac ataacttttt
      781 ccatatcttt ttctgaccaa tggaaattgt ctaatacttt gtaagcttct ggctggtctt
      841 ctttcaatcc ttttcgaacc atcgtatgga tctgctcttc gcttcccatt ccgttttcag
      901 gatcttctaa gtatttcaga tcatatttgg caaacatcca atgaggtgtc catcctgtaa
      961 ctacaattgg ttcgtgtttt ttgatcgctt gacctagtgc aacggtcatt gctcctgaag
     1021 aagatgtctc tactttccag tctttcaagt tgtcatattt ttggatcgtg ttttcagcag
     1081 ccgtaactac accagctcct ggctcgattc ctatgatttt cttacctgcc tgatcggtta
     1141 actcatcgat cgaatttaca tccatgtagg ctggcactgc taaaccaact tttgctcctg
     1201 tcaaattggc acctaggtct tcgacttgat ctttatattg tgcatattgt gaaccatgag
     1261 ttttaggtag ccaagctgaa accatggcat ctgactcgcc atttgaaaca gatttccaca
     1321 tgattgaatt atctaatggc gtcatcgtta catcatagcc catttgtttc aatacttcac
     1381 cgactacatt tgttgaagca acttctgtat cccattcaac ataagataag ttgatacgtt
     1441 ttgtttcttt ggcagatgaa aaactcccta taccaatcgc acctaagatc actactacta
     1501 cagcaccaat gatcagtcct tgacgttttt tacttttctg tgttgttgct cctgcagctt
     1561 ttttattgtt tggctggttc aaatgctgtg taaaacggtc aatgatgatt gctaagataa
     1621 ctaatgcaac cccgttgaca aatccattcc cgacttgtgc tctttgcaat gctgataata
     1681 cgccgcgtcc taagccgggt gcaccgatca tagaggcaat aacgaccatt gaaagtgaca
     1741 gcattgttgt ttgattgatc cctgccatga tcgtactttt agctaaaggc aattctagtt
     1801 tgaatagttt ttgacgactt gtgctcccga atgaatcaga agcttctact aattctttag
     1861 gaacttgtcg aatccctaaa ttcgtaaaac gaacggttgg tggcagagca aagatgactg
     1921 aggcaaatac ccctggaacc atcccgatac cgaaaaatgc aactgctgga atcaaataaa
     1981 cgaatcctgg cattgtctgc ataaagtcaa ggatcggttt gataatactt tgggctttac
     2041 tgctttttgc catcaagatc cctaatggta ccccaatgat gatcgagatc acactagata
     2101 aaagaacaag tgtgacagta ttcatcaaat cattccatag accttggtta taaataaacc
     2161 atagaccgat taatgtgaac aacgtaagtc ctggacgttt cttagaaata aagaaagctg
     2221 ctaccgtcaa taacaagata aacaaaggag ctggaatcac taacagtaaa tttgtaatcc
     2281 ccgacatcac tgcctgtcca atcgtttgta aaaatgaaaa taggccagaa aaagttgtcg
     2341 taaaccattc tgtgatattt tctacccagt ttgccactgg taattgatag ttcaatagat
     2401 tattcatgtt cactcacctc gcttgtttct gctaatgctt caatcacact acctcggatg
     2461 acgacacctt ttaattttcc atcctctaca actgcaagtg gagtcggtga gtcataaata
     2521 atattgaaaa tatcacttac caccatgtct ttcccaatca ccgtcacatt ttcatctagg
     2581 aagtcgatca atggacgttt ttgcttccta gcttctaacg cttgatctgc agtgatgatc
     2641 cctttcaggt gtctctttct gtcaacagcc atcagcatgc tgacttcttc attacgcatc
     2701 cttgtcaatg caacgtttgg tccatcagat tcgatattcg tcgtcaatgc aggtaccatg
     2761 atgttttgag ccgtaagcac tttggaacga tcgacttctt ccacaaattc acgtacataa
     2821 tcatttgctg gattggtcaa tatttcttca cctgttccga tctgcatgat ttcgccgtct
     2881 ttcatcaagg cgattctgtc cccaatccgt aaagcttcat tcaaatcatg ggtaatgaaa
     2941 ataatcgttt tttgaacatt ggcttgcagg tccagtaatt cgtcttgcat ttctcgccgg
     3001 atcagcggat caagagccga gaacgcttcg tccatcagca agatctcagg atcatttgct
     3061 aaagctctgg ctaggccaac ccgttgttgc atcccaccag ataactgact aggatattgg
     3121 tctttaaatg aaagcaaact agaattttct aatgcttttt ctgctttttc ttgtcgttct
     3181 tctttaggta caccacggac ttctaacccg tattctgtat tttccaagat cgttcgatgt
     3241 ggaaacagac cgaagttttg gaaaaccata ttgattttat gacgacggac ttctcgcaat
     3301 tcttctttgc ttaacttcga tacatcttct ccatcaatat agatactgcc cgaagttggc
     3361 tcaatcagac gattcaatag acggatcaat gtggatttcc cactcccgga aagccccatg
     3421 atcacgaaga tttctccttc ttttacgtca aaattcacgt catacacacc aaccgttgca
     3481 ccggttttct ttaaaatctc cgttttcggc tggtgatcat tcatcatatc taaagcggct
     3541 tgtgtctttt taccaaatat ctttgttaaa tgttttactt ctacttttac caaacaaatt
     3601 ctcctttttt atgtaaattc atttttcttt ctgaaaaaag tgaccacact atgttaacat
     3661 catgtagtca ctttgtcaaa aatgaaagaa atttgcttgt ccaaactgaa aaaaacttgg
     3721 ctaaatcttt gtaaataaaa ggtttagcca agttaatatt tttttaatat ttcacacaat
     3781 cattctgcaa gctgatgctc cgggtaaaaa aagtttgtca tacgctgtag tgtatattca
     3841 tttccaataa aatgaacgat gtcccctgcc gtaaatttag cataggggcc aggtgaaaca
     3901 agcagttctt cattatgaga aattgcgata actgtggcgc cagtcgcctg ccagatattc
     3961 aactcgctaa ttgaacggtc cagatgcatt gctttttctg ataaagataa ttcaaacgga
     4021 agtaaaggat tcatcttatg tattcgcttc gtttgattga ccagctgatc caataattga
     4081 gaaaaatgat tcagctcatc ttgttgcttc tccacacttg ccatgatttc tgcttttgta
     4141 tcttggatgg attgtacatc ttgatattgc aataggaaat cttttgcttt ttccttcgaa
     4201 gcaacaaatg ccccacttcc atgccgtact tccatgattc caagatctac cagcacattg
     4261 atagccttgc gggtagtctc aggagaagca ttgtacgtac tggcaagtgt tgagcgggca
     4321 tggatcttct cacccacttt atatcggttt tcaacgatac gttcggctaa atcaacagca
     4381 atctgctggt agcgcgggcg gacgattttt ttctttccag acattttctt tcctctttct
     4441 ttttttactt tccctcatct tactatgctc tagcaaaata agcaaaaaag gggagaatag
     4501 cctcttgcaa cgactgatca tcgcttgatc tgttcctttt ttactgggca agctgtttga
     4561 cagtcatcac aattcttacc ggattttaaa cgagtataga caattgcgcc tgcacttcca
     4621 aagattaaca cacttaataa gaatgtcgcc atcctattcc tctccttcta atgacaatat
     4681 agtataaaac tggttcttgg attttggctg acggaacaaa acataaacga gtcctatcat
     4741 cagtaaaata gcaagatacg tccctaacgc tacctgtcca ccctccaata agtgtcccaa
     4801 ctgataaatc acaaaactaa ctaaataagc taaaccgcat tgatagccta tggcgatcca
     4861 agtccatttc ttggcattca tttcccgatg gatagcccca attgccgcaa aacaaggcgc
     4921 acaaagtaaa ttgaaggcta acaatgaata agctgctgcg ggagtatatg tgtgttgtag
     4981 cacttgccag atttctctgc cattttcgga tacttccgca tgaccaaaca aaataccaaa
     5041 tgtgccaata atattttctt tagcgaccaa tcctgtaatc gctgcgactg ttccttgcca
     5101 gtttccccaa ccaagcggct gaaaaacaac tgccaggatt cgcccgaaaa aggctaagat
     5161 actttggtct tcagaaacag gttgagcata aaaattataa gaagagctga accagatcac
     5221 gatactagaa acaaagataa tcgttcctgc ttttttaaca aaagacttgc tgcggtcata
     5281 ggtttgtctt aggaccgctg accattgagg aaaatgatat gcgggcaatt ccatgataaa
     5341 aggagctgta tctccagcaa acaaacgtgt ttttttcaag ctgattccag agaaaataat
     5401 tgcagtcata ccaagaaaat aggcagaagg agctacccaa gattgatgag gaaaaaaggc
     5461 ccctgctact aaggcaataa tcggcaactt tgcagaacaa ggcatgaagg ttgtgaccat
     5521 gatcgtcaaa cgacgatctt gctcgttttc aatcgtgcga ctggccatga cgcctggcac
     5581 tccacatcct gtagcaatca gcataggaat gaaggatttt cctgaaagac cgaatttcct
     5641 gaaaagtcga tccatgacaa aagcgatcct cgccatatat ccgcagtctt ccagaaagct
     5701 caagcataaa aacaatataa tcaattgcgg tagaaatcct aacactgctc ccacgcctgc
     5761 gatgatgccg ttcaagatca gctcctgcat ccatcccgct acttgccatt cagctaacaa
     5821 tctgccaaca tgttctggta accatgtacc aaacaatgtg tcattgatcc aatctgtccc
     5881 cattgttcct actgtttgaa tagccagata atagatcagc cacatcacaa atgcgaagat
     5941 cggcaaggct aaccaacgat tcgttgcaat ctgatcgatt ttgtcactca tcgataattg
     6001 gaaagaatca tttgacacaa cacagagtgt acatagttgg gtaataaatt cataacgttc
     6061 attgaccaga atcgtctcac tatcgtcgtc caatagtttc tctgttaact ggatcagttg
     6121 ctcgatctct ttttgctgag aaactgctat ctcgtaatcc tctcttacct tctgatctcg
     6181 ttcaaaatat ttcattgcat accagcgttt cttgccgctt tgttctccta gtacatcttc
     6241 aatttcatgt aaagctgctt ctaaacgtgg atcatatgta cagggaacag gaatagaagg
     6301 ccgctttttt gcagactcct gaatcttttc gattagtttt tcgattcctt gctttttcaa
     6361 tacgctgatt ggtaaaactg gtacaccaag accataggaa agcttttcta gattgatttt
     6421 ttttccttct tttttgatga catccatcat attcagacca atgatcatag gaatgtctaa
     6481 atccaataac tgcgtagtta aataaagatt tcgttctaaa ttggtagcat caataatgtt
     6541 gatgatcagt tcaggctgtt cctgaaccaa ataatctctt gcaatcactt cttctggtgt
     6601 ataaggagac aaagaataga tgccgggtag gtcctgaata tgaatgttcg gatttttttt
     6661 caacgatcct tctttttttt ctactgttac gcccggccaa ttccctacat attgattcga
     6721 accagtcaag agattgaaca agctagtttt cccgctgttt ggatttccga ctaacgcgat
     6781 attcattctt tttcctccct ttgtatcaag attagttcgg cctctgactt tcgtaacgtc
     6841 agttcatacc ctcgcactgt cagttcgatt ggatctccca gaggggctag ttttcggata
     6901 actattttta catttcgcgt caatcccata tccattaacc gtcgcttcac tgcgccttgt
     6961 ccgtggattg ctacgacgat cccagtctct cctgctttta attgatcaag agaagtccag
     7021 ctttcagagg aagcagtctt tttattgaca aagatttgac ctagtatttc ccgacttact
     7081 gccactcgat gactttttac cagtaaaatg gcattgttgc ctgataaatt gacgacgacg
     7141 attttacttc cggcaacgat cccgatattt tgcaaatggc gttttgtttt ttcttctgtt
     7201 tcgattcgtt cgacttgata aacgaaattc tgctttgcct gcgctaaggt ctgcatattg
     7261 attcctctct tgtgaaataa atcatgtatt aaaatcattc attatatgtt ctaattttct
     7321 tacgtgttac gcaaataaat gagaatcatt ctcacataga atactctcgg taattgagaa
     7381 tgtcaattat acttgtgata ttatgagcga atctttagta ttgatagata aaaatgagaa
     7441 aaaaatattt cttcatagtt ttccacaatt ttttctctat taaatttgct attttcccac
     7501 acgatacttg ttttcagctc ttttttcaaa aacacaaaac ttagtattcc acagtttcca
     7561 caacacaata tgtagtgttt gttgtttgac ttttttacta agagttttat actatctatt
     7621 atagataata agaatgtgtt agaggaggca ctcaccatga acgtaaaaat cttttctaaa
     7681 aataattgta tgcaatgtaa gatggtcaaa cggtttttaa cagaaaatca aattgctttt
     7741 gaagaagtca atatcgatga acagcctgaa gcagtagact ggttgaaagc acaaggattc
     7801 caaagtgttc ctgtcattac ttctgatgca gaaacagtta tcggattccg tcctgatcag
     7861 ttgcgtaaac ttgccagcta acatgactaa aagaatcaaa acgtgataca tggatttgaa
     7921 gggcttgaga cagcaccagt ttttgtcgca aacttccaaa tcctttttta aagcttaaaa
     7981 acaatgcaat gatttgcaat caagcatcat caaatacgaa atgaaggttg ggcgtacgta
     8041 tgagtcttaa aaatttacaa gatgtcagtt atttcaagct gaataatgaa atcaatcggc
     8101 cagtcaatgg tcaaatccct ttgaataagg ataaagaagc tttagttgcc ttttttgagg
     8161 aaaatgtcaa accaaatacg atgacttttc tatctattat ggaaaaaatc aattacttga
     8221 tcgatcaaga atatatagaa gcagaattca ttcaattgta ttcaccatca tttattgaaa
     8281 agctatatca atttttggac gagcaacatt tttctttcaa atcttttatg gctgcttaca
     8341 aattttattc tcaatatgcg ttgaaaacca acgacggttc cgcttatctg gaaacttatg
     8401 aagatcgagt agccttcaat gcgctttact ttgcgaacgg ggatgaagaa ttagcacttg
     8461 ctcttgcaga cgaaatgatc catcaacgat atcagccagc tacaccttct ttcttgaatg
     8521 ctggacgtaa acgtcggggc gaattggtgt cttgtttctt gactcaagtc actgacgata
     8581 tgaactctat cgggcgctca atcaactctg ctttgcaatt gtcccgtatt ggtggcggcg
     8641 tagggattac tttatcaaat cttcgtgaag ccggcgctcc tatcaaagga tatgagggtg
     8701 ctgcaagtgg tgtcgttcca gtcatgaaat tattcgaaga tagtttcagc tattctaatc
     8761 aattaggtca gcgtcaagga gctggcgtgg tttatttgaa cgttttccat ccagacatta
     8821 ttgctttcct ttcagcaaaa aaagaaaatg cagatgaaaa gattcgcgta aaaactcttt
     8881 ctcttggcgt gatcgtacct gataaatttt atgaattgac acgtaaaaac gaagatatgt
     8941 atttatttag tccatatagt gtcgaaaaag aatatggtgt cccattctct tatgtaaata
     9001 ttacagctga gtatgatcat ctagttgcaa atccaaacat tcgcaaacaa aaaatcaaag
     9061 cgcgtgatct tgaaaatgaa atctcaaaat tacaacaaga atctggctat ccttacgtaa
     9121 tcaatattga tacagcgaac cgcgagaatc caatcgatgg caagatcatc atgagtaatt
     9181 tatgttcaga gattttacaa gttcaaacgc cttctgtgat taacggcaaa caggaatatg
     9241 aagtattagg aacggatatc tcatgtaact taggctcgac aaatatcgtg aatttgatgc
     9301 aaagccctaa ctttggtcaa tctgtgcgta cgatgactcg tgcattgaca tttattacag
     9361 atgcatctga tatcgatgtc gtaccaccga tccaaaacgg aaataagctg aatcatacga
     9421 ttggattagg tgccatgggc ttacacactt atcttgcaaa agaacaaatg gaatatggct
     9481 cagaggattc attagacttt acaaatattt acttcatgct gttgaattat tggacacttg
     9541 ttgaaagcaa caatatcgct cgtgaaagaa aacaagtttt ccataatttt gaaaaatcag
     9601 cttatgctga cggcacttat ttcgaaaaat acgtaactgg agaattccag ccaaaatcag
     9661 aaaaagtcaa agcattgttt gaaggcattt ttatcccaac tgctgaagat tggaatgctt
     9721 tgaaacaagc agtaatgaaa gatggactgt atcatcaaaa tcgcttggca gtagcaccaa
     9781 atggctcaat ttcatatatc aacgatacga gtgcaagtat tcatcctatc actcgcatga
     9841 tcgaagaacg ccaagagaag aaaatcggta aaatttatta cccagcgcct tatctatcca
     9901 atgagacgat tccgtattac acttctgctt atgatatgga catgcgtaaa gtaatcgatg
     9961 tttatgcaat ggcacaacaa cacgtcgatc aaggcatgag tttgacttta ttcatgcgtt
    10021 ctgaaatccc agaaggcatt tatgaatgga agacaacaac gaagcaaacg acacgtgatt
    10081 tgaatatttt aagacattac gctttccaca aaggaatcaa atccatttat tacgtacgta
    10141 cctttactga tgatgcagaa gaaatcggaa gcaatcaatg tgaaagctgc gtgatctaat
    10201 atcatagata gattcgctta ttcatatttt aattaaagga gcattctcat gtcagaaaca
    10261 tattatgaag caataaactg gaatgaaatt gaagatatca ttgataaatc cacttgggag
    10321 aagctgacag agcaattttg gctagataca cgtatcccac tttcaaatga cctagatgat
    10381 tggcgtacat tgtctcaatt ggaaaaagat acagtaggac atgtatttgg cggtttgaca
    10441 ctgctagata ctgtccaatc tgaaagtggc atggatcagt tgcgtaaaga tgtccgcact
    10501 ccccatgaag aagccgtttt gaacaatatt caattcatgg aatccgttca tgccaaaagt
    10561 tattcttcta tttttagtac actgaatacg aaaaaagaaa tcgaagaaat ttttgactgg
    10621 acaaatacga atccttatct gcaaaaaaaa gctgagcgta tcaatgaaat ctacaaacac
    10681 ggtacaccgc tagaaaagaa aattgccagc gtctttttag aaacattctt gttctattca
    10741 ggtttttata ctcctcttta ttatttagga aacaacaaat tggctaacgt agcagagatc
    10801 atcaaactaa tcatccgaga tgaatctgta catggaacct acatcggtta caaattccaa
    10861 ttaggattca acgagttacc tgaagcagaa caagaaacgt taaaagactg gatgtacaat
    10921 cttctttatg agctttacga aaacgaagaa cgttatacag aagaattata cgatccaatc
    10981 ggctggacag aagaagtcaa gacattccta cgctataatg ccaacaaagc attgatgaac
    11041 ctagggatgg atccactctt tccagatact gccaatgatg tcaacccaat cgtaatgaac
    11101 gggatttcaa caggcacaag caaccatgac ttcttctcac aagtcggaaa cggctatttg
    11161 ttaggtcatg tagaagcgat gaaagacgac gattatttga ttggattgga ataaggattt
    11221 attttaattc aaaaattttt cgaaaaataa aaagagttta gcgtacagat attttaaatg
    11281 tacactgaac tcttttttat gcttattcac ttgtttcttc cagcactttt ggactgtcta
    11341 acttttccga aacatgttcc attcttctca ataaatagat tttccggata tttaatatta
    11401 tcgtcttaat cactgcatag acaggtatgc aaatcagcat gcctaatatt cctgcgacac
    11461 ttcctgctcc aatcaatacc aagatgatcg tcaaaggatg gatattcatt gatttcccaa
    11521 ataacaacgg cttgatcaaa tttccatcta attgttggat cactaaaatc gacaacgcca
    11581 tatacaaagc ttgaaatgga gagataaaca aaccgacaat gattgctggt accgctccaa
    11641 taaaagggcc gacatacggg ataatattcg tgattccgca aatgaccgca agcaacaagc
    11701 tataaggctg atcgaatatt ctcattgcca aaaagctcat tacaccaata atcaaagcat
    11761 ctaagatcgt actgctgata taggcagata atgtttcgtt taattctttt accgtttggc
    11821 gtaactcttt acgaatcgct ttcggaaaga agtgagacaa cgcatcaata aatttgtgcc
    11881 catccttgaa cataaatagc aaaataaatg gaacggtaaa taacaaaata aaaaattgca
    11941 tcataaatga aatgattttt gagacacttg cagataaact gactaatatg atattgaaca
    12001 aattactaag agataaattt gctgatgcta attgttcttc caaattgaaa tttttaaact
    12061 cttcccgctg cgccaattca tttaaccatt tgcttgtttc atctgcatac attggcaagc
    12121 tctgggtcaa ttgaattgtc tgttccatta actgaggcac tacattcatg acagttaaaa
    12181 caactaaaat gattacgacc aaaaacgtca ataaaaaacc gaacactctc gggatccgat
    12241 gcttttcgag aaaaacaacg attggatcga acatataata gataaaacca gcaacaagca
    12301 atggtaaaaa aactgccgaa agcattttca atattggact aaaaatattc ggcatttgta
    12361 aaataaagta cacgccgatg atcgtgagta ctagctccac tgtccagaaa aataattttg
    12421 attgtttaaa acgtgattgc atacatctcc tccaaggtcc tttgatactt ctattctatc
    12481 atttaacaaa gagttacgcg ctgagatttt catttgctta aaaaaaacaa aaaaaataaa
    12541 catattttaa tgagtagacg agtacttaaa caaaaacacg gtttggagta gtgacaaaaa
    12601 ttatactgca gtcccttttt ccaaataaac ggtgttcaaa agcttgcatc ttcgtaataa
    12661 gcccagccaa acgaaaaata taaggaacta tttttatttg gctgggctta ttacttgatg
    12721 taggacatct attttacaac ctcagatcat ttattgcgca atactgacta aatgcaactt
    12781 tgtgatattt ttgtgtacgg acaactcctc gatcacatcg gcataagtga gcccttttgg
    12841 aagatcaatc gtatagatat ttttgtacac tcggtagtca tcaacgaatt ttacgtcaaa
    12901 attcacatct tcgattacga tatttttctc ttcaaaataa tcggtaagaa aatctttggt
    12961 ttcttttcta tggataaatt ggatttctaa ctttttagtc gtaggtacat ggatcacgcg
    13021 tttcactact gtgagtgcaa tagcaatccc gataaaactg atgatcgcaa tggaatagta
    13081 acccatgccg atggcgatcc ctaatccagc aattgcccat aaagaagcgg cagtcgtaag
    13141 tcccgtcacc gattgtttcg tgacgatgat cgttcccgcg cctaagaaac cgacaccact
    13201 caccacttga gcaatcagcc ttgcttcatc tgaacgaatc gttccagcaa gctgtggata
    13261 ctctaaagca tctcttaatg caccactagc gatctcaact tggatcaatg caatgataca
    13321 tgctcccata caaactaaaa tatgcgtacg catacctgct ggacgatttt tatattgtcg
    13381 ttcaaaaccg attgctccgc caaatagcat agcgatccct aaacgtaaaa taatctctgg
    13441 aattgtcaat accatatcat tcatctaaac accctccagt ccaatatatc atgtctgaaa
    13501 ggagcagaca aaaaaagtgc aatttttacc tcttacgaaa aaaggactgt gacaaaattt
    13561 ttgtcatagt cctttttatg aataaacggt gttcaatcag ctgaccctcg gtattactca
    13621 acaaacggca aaatatgggg agctattttt cctttgtctt ctctaatact caggtcaaaa
    13681 cgctgatttc acaacctctt tagcctacta ttgaaaatta caacttactt gctgcttctt
    13741 catcgatgat cacaacaaca ttgtcgtgat tttgcaatac acttgctggc aaatgattcg
    13801 ttacaggtcc ttcaatcatc cctttgattg catcagcttt gctttcgcca aatgccatca
    13861 agacgatttc tttacttttc ataattgaac cgattcccat tgaaacagct tttgttggta
    13921 catcttctgc tttatcgaag aatcgtttgt ttgcattgat tgttgattct gttaagtcaa
    13981 ctactgaagt cgttccgtca aatgaagcac caggttcatt gaaaccgata tgtccatttt
    14041 gcccgattcc taagatttgg atatcgattg gatgtgcatc gatgatttga tcatactttt
    14101 tgcatgctgc ttccagatct tctgcttttc catctggtac aaacgtttct ttgaatggtt
    14161 ttttatcaaa taattggaca tccatgaaat gacggtagct ttgttcatct gaaccgccta
    14221 gtccaacgta ctcatctaag tttacagaag tcatttcact gaaatccaaa tcgcttgaag
    14281 tcatttcttt atataaagta actggtgtgc ttcctgttgc caatcctaat acttttgcac
    14341 ctttgttcat accttctttg atgatttcaa atgctttttt tccgccttct tcagcgtttt
    14401 ttacacgaat gatttccata gtgattgctc ctttatattt tggtatagcc caattatagc
    14461 attctttttt tctttttaca ataattagta tagaccaaat tgcatttttt tcattttctt
    14521 gacaataaat aggaatccgt gttaggtttc ataagatggt tcaatcaaac aatccatgtt
    14581 gcatgaaaac caagcaagtg attcactgtg gacgctttat gtctgcagtt tttttatgaa
    14641 aaaggagtta ttatgagtat actgacatta aacaacatta cccagcaatt tggcgacaaa
    14701 atcctctatg aaggtgtcga tctgcaatta aatgctggcg aacatcttgg gctgattgga
    14761 caaaacggag ccggtaaaag tacattgatt aaaatcatca ctggtgagat cttaccagat
    14821 gacggacaga tccattggca aaaaaatatt cacaaaggtt acctcgatca atatgtggaa
    14881 gtcgatgaaa cattaacaat cgaagaattt ctaaaaactg cgtacgcaaa agaatacgaa
    14941 aaggaagaaa aaattgcttt tctttaccaa acatatagcg agaccttcga tgattccttg
    15001 ctggaaaaag ctgggaaact ccaaacggaa ttagaccaag gagtgtttta tcaaatcgac
    15061 accttagttg ctgagatgag cagcgggttg gggatcgatg tcttaggttt agattcactg
    15121 ttgaaaaatc taagtggtgg acaacgttca aaggtgattt tagcaaaact acttttagaa
    15181 aacccagatg ttctgatctt agatgaacca accaatcact tagatgatca gcatatccaa
    15241 tggctgacgc agtttcttca ggattttgac ggtgcgtata tcgtgatttc ccatgaccaa
    15301 gaatttcttg atcagatcac cacccatatc gcagacatcg agtttggaaa gattactaag
    15361 tatactggcc atctaaaaca agcattgaaa caaaaggaac aaaatcgcga aagctatttg
    15421 cgccaatatc atgctcaaca aaaacaaatc gaaaagaccg aagcttatat tcgaaaatac
    15481 aaagccggtt cccgatcaac gatggcaaaa agccgacaaa aacaattaga taaaatcgaa
    15541 cggctgacgc ctccagcttc agcaagtaaa gctgtctttg attttccatt ctcgcctatt
    15601 gtcacgacat tagcagtgga aacaactgat ttagtcatcg gatatgatcg accgctactt
    15661 gcacccatca atttgaccat ccgctttggt gaaaatattg ccattcgagg cttcaacggg
    15721 attggaaaat ctactttatt aaaaacactg atcggtgaga ttgaaaaaat aagtggcgat
    15781 ttccacttcc cagataacac aaaaatcaat tacttttcac aagatctgta ctgggaaaat
    15841 ccattagaaa caccactaca atatttaagc agtcaatttc caaaagcgac tatcaaagaa
    15901 ttacgtcgcc aactagctaa agcagggtta gttaatcaat tagcaagtga acctctcact
    15961 acattaagtg gtggggaaca aactaaggtg aaacttgcac agttgacaat gaaccaaggt
    16021 aatttactga ttctcgatga accgacgaac catatcgatc aagaaacgaa agaaagctta
    16081 caagacggga tacagaaatt tccaggaaca gtaatcatcg tctctcatga acaagaattt
    16141 tatcaagatc ttgtgcaacg agtcattgag attgaaccaa aataaacgtt tgattgaata
    16201 gttgaaaaaa aggagctgtg acaaaagttt tgtcacaact ccttcttctg aataaatggt
    16261 ggccaattag ctgaccttcg gtattagctc aaaaaacggc aaaatatgag gagctatttt
    16321 tatttggcta ttcttattac ttgatgcaga acagcttttc acaacctctt ttcgtctatt
    16381 ttttattttc gagatttctc tttcctttaa aaacaactgt ttgaaagaag aacgcacatc
    16441 cttgaaaaac aagcccgcta accgttacac ctaaccagcc atactgctgc cacattgtcg
    16501 tccctagcaa tgaaccagcc gcacctccaa taaagtacat aaacataaat acagtattat
    16561 ttcggttgct tgctgcttca cctagccctt gtactcgtgt ttgattggcg acttgaccaa
    16621 attgattccc gacgtctaat aaaataatag ctaaaagcaa aatggccaaa tggcttccgc
    16681 caaccaataa agcaataaag cttattgttt gcataacaag tcccatatac acgatttttc
    16741 tttcagaata agaatctgcc agtcgtccca cgataggtgc agcaactgct ccagacaaac
    16801 caaaaatcgc taatatccct gcttcgaatg ttccccaatt gtaggcggga ctgctgatat
    16861 aaaaaatcaa cgtagaccaa aagatcgaaa atgttccaaa catgaaaaat ccactgactg
    16921 ccgcttctct taatagacgt tgagaagcaa ctaaatgcgg caaactttta agtgaatcaa
    16981 ggtatgaaac agctgtacta ctttgctgga cagaacgcgg cattttccag taaagcagaa
    17041 gtgtaagaat tccgactgca cataaagcaa ataaatagat catccgccaa gaaaaaagac
    17101 tggcaacaat accagatacc gtccgagaaa gcaaaatccc cacgagtaaa ccgctaagca
    17161 atgtacccat gaccttccct cttgcttttg gtcccgctag taccgcaccg taaggaatga
    17221 tgatttgcgg cacgatcgaa agtaatccta ttaaaaaaga agcgcatgca aataacgtaa
    17281 acgaaggcgc aaaaaaagcg gccaacagag agacggcaga taacgctgcc attcgaatga
    17341 tcaattttgg acgatccacc acgtccccta aaggaactaa aaacagtaac cctaacgcat
    17401 agcctaattg ggtcaacatc gtcaatatcc cgactgcact tgtgctaaca gataaactag
    17461 ctgctacttt tgttccaatc ggctggatgt aatacatatt ggcaacaaca acgccacaag
    17521 tgattgataa tagtaaaata agcgaagttg ttaaaggttt tttttcatta ctcttcattg
    17581 atttccccca tttcctatct tagtttacaa cttatggaaa agattggaaa tagaaaaata
    17641 caactattcg ccacacttat tatttgtgct tttgttttcc ttgttttttc ttgcgatctt
    17701 tataaatgaa gacaactaac cctactagca cagtaacact tgcaaccaac gtgactgcag
    17761 ttttgttata tccgtgaaac agagcttctc caccacacgc atacaacaca gacgaaggga
    17821 tgactccaat cacgatcgac aatatgattt gctgtagagg caatttcatc gcatctgcag
    17881 caaaattgac catagaagat ggaataaccg gtatcatata gcctaacatt acacctattt
    17941 ttggatgttt catttgtcgg attgcttgca cccaatgatt cgtttcggtt ttcttatcta
    18001 aaaattttaa gcgatgcata aggaaaattg cagtgatgtt accaagagca ttacccaaaa
    18061 tgttgatgat cgcacctgtc agtggtccaa agctcaaacc agcaatgact ccaactactg
    18121 aagtaggaat acctggaaca gcacacatca ccgctgtcaa tacgatcaag agtatcgatg
    18181 caaaagtccc atgcgaacga atatgtgcga gtagctctgc cttactcgct ctcggattta
    18241 aaaataattg gatgtctgtc tgatattcta aatacaaccg atagcccact accagtatca
    18301 gaatgattcc caacgagatc aatatcaatc ggattatttt ctttttcata tttcctcctg
    18361 aaaaaaatct atattcatta aataatagtt taacataaaa acaaaaaagc accgaaatcc
    18421 aacataggat ctcagtgctt ttaaatagta aaaattattt aacagttaca gatgcgccaa
    18481 cttcttcaag tttagctttc aattcttcag cttcttcttt agatacgcct tctttaactg
    18541 gtgcaggagc gccatcaact acagctttag cttctttcaa gcctaaacca gttgcttcac
    18601 gaactgcttt gataacttta actttttggt ctccagctgc agttaattct acagtgaatt
    18661 ctgtttgttc ttcagcagca gcagcgccac cagcagcagc tacagctaca ggagcagcag
    18721 cagatacgcc aaattcttct tcaatagctt taactaggtc gttaagttct aggatagttg
    18781 cttcttttaa ctcagcaacg atgttttcaa tgttcaatgc cattataatt tcctccgttt
    18841 aattgttctt ttttatttaa tgctttatgc ggcaattaag ctgcatctcc atcttctttg
    18901 tctgccactg ctttgacagc gtaagccacg ttgcggactg gcgcttgtag tacagatagc
    18961 aacatagata gaagtccttc gcgatttggc aattttgcca atgctgtgat ttcttccaat
    19021 gaagagactt taccttcgat gataccgcct ttgatttcta atgcttttgc ttctttagca
    19081 aattcgtcca tgattttcgc tggtgcgact acatcttcgt tactgaatgc aacagctgta
    19141 ggtccagtga atacttcgtc catgccttca aggccagctt ttttagctgc acgtgaaaga
    19201 atagaatttt tgataacttt catttctacg ttagcatcac gaagttgttt acgtaaacgt
    19261 gttacttcat caactgttaa tccgcggtag tcaacgacta ctactgatgc agctgctgta
    19321 aatttttcgc ttacttcatc aacgattgct gctttttttg cgataattgc ttcactcatt
    19381 tttgagtttc acctcctgaa ttttgatgga agagtttttt gcactgaaaa ggcaagtcac
    19441 ttttatagtt actttgctca accagtatta ttcatcacct attcacttcg ttcatagtga
    19501 ttctactcgc tttgctcgaa aggaaactcc tttcgctttg ctcaaccagt attgttcatc
    19561 atctcttcac ttcgttcata gtgattcaca ataaaaaact ctatgccacc gcagacatag
    19621 agggactatt gaatatattc aataaacgtc ctcggtagga aattaaggct tgatgccacc
    19681 tactgtcttc ggtacaagtt aattattaac ctcaactagc ttagcatgct aaactagttg
    19741 agtcaagaat tatttttcag ttggatcaat caacattcta atatttaatt agaaagaagc
    19801 ttggtcaaca tggataccag gtccaaatgt tgttgtgatc gttacatttt tcatgtattg
    19861 acctttagct gctgatggtt tagcttttag caatacatca tggattgctg caaagttttc
    19921 aactaatttt tcatcgtcaa atgaaacttt tccgattggt acatggatat ttccagcttt
    19981 gtccacacgg taagttactt taccagcttt cacttcgttt actgcttttg ttacgtccat
    20041 tgtaactgta ccagttttag ggtttggcat taagcctttt ggtcctaata ctcgtcctag
    20101 acgacctaca gtagccatca tatcaggtgt tgcaacaact acatcaaagt caaaccatcc
    20161 gttttggatt ttttgaacca tgtcgtcgtc acctacgaaa tctgcaccag ctgcttcagc
    20221 ttcttttgct ttgtctcctt tagcaaaaac taaaacagtt tgtgttttac cagttccgtt
    20281 tggtaataca acagcaccac ggatttgttg gtctgctttt ttagggtcta cgttcaaacg
    20341 gtatgcaact tcaactgttg catcaaattt tgcaatgttt gtttcttttg ctaaagctac
    20401 tgcttcggca acaggataaa ctttacttga atcaactttt tttaatgcat cttgcatttt
    20461 tttgctcttt ttagccattt tggttcctcc ttgattgtgg ttataacggt tgtacctccc
    20521 acgtgttcta tatctttcaa tatagagcca actgagaagc tgctgtctta gggtgtatag
    20581 attattctac agtgatcccc atgcttcgtg cagttccttc aaccatgcgc attgctgctt
    20641 caacgttagc tgcgtttagg tcttccattt ttaattcagc gatttctctt acttgatcgc
    20701 tagaaacttt cgcaacttta tttttgtttg gttcgcctga acctttttcg attttagctg
    20761 cttttttcaa tagaacagca gctggcggtg tttttgtaac gaatgtgaat gaacggtctt
    20821 cgtatacaga aataacaacc ggaatgatca aacctgcttg atcagctgta cgagcgttga
    20881 attcttttgt gaatcccatg atattgatac ccgcttgacc tagtgcagga cctactggtg
    20941 gagctggagt tgctttacct gcaggaattt gcaatttaac gattttttct actttctttg
    21001 ccacgagaca tacctcctta agtccgtgat gtggttaatt ggagatgcat atttctcctc
    21061 ccacgtttta tctgatctga aaaaatccag acaaataatg tgcaaaacaa tgcacactgg
    21121 tacagtatag caaatttatt tgttttttca agattttttt ctgctatttt tacattttgc
    21181 ttgaataaac gctaaattta ttctaaaaaa acaacaattt ttcgttctca tttcttcttt
    21241 tatgttacac ttgcgctagc atggttcaac agatgaaagc aaacaataac acggtttttt
    21301 agacccttgt acaaagattc ctacataaca aaatgaggtg gagaaaatga aagatttaag
    21361 gtatagaagt gtctttgata ttattggacc tgtgatgatt ggtccaagta gctctcacac
    21421 tgccggagct gctagaatcg ggaaaatcat acgtagtata tttggcgaac agcctgattc
    21481 tgtagatatt tatctatatg aatcatttgc aaaaacctat cgggggcacg gaacagatat
    21541 tgcattagtt ggcggcctgt tagggatgga acccgatgat gaacgtttag ctgattcttt
    21601 gaaattggca tatgaagccg gtatggaagt cttgtttgtt cctaagagtg aaaaagccga
    21661 acatccaaac tctgtaaaga tgcttctaaa aaaaggaaca cgaaagcttt cagtcactgg
    21721 catttcgatc ggcggtggca atatccagat ttctgaattg aatggattca aaatttcttt
    21781 aagcatgggt actcctacct tgatcgttgt ccaccaagat gttccaggta tgattgctaa
    21841 agtgactagt atactttctg agaccaatac gaatatcggc actatgacag tgacacggga
    21901 atcaaaaggt gaaaatgcca ttatgataat tgaagtagat gatcctcaag tagaagaaac
    21961 ggtaaaaaga ctcaaacagc tgccaaatat cgacagcgta aattatttcg attaaggagc
    22021 taaaaaaatg tttttatcga ttgaagaatt agtagatcaa gcaaaagctt atccaagtgt
    22081 agcagaattg atgattgcag ttgaaatgga aatgagtggc cgttcccgta gtcacatcat
    22141 cgagatcatg gaaaaaaacc tctcagtaat ggaacaatca atcaacgagg gaaaagaagg
    22201 tgttacctcc gtcacaggaa ttaccggtgg tgatgcaaaa aaattagatg attatttaaa
    22261 tgaggcagac tttttaagtg gagaaacaat cttaaaagct gtacgcaatg ctgtagctgt
    22321 taatgaagtc aatgcaaaaa tggggttgat ttgtgctaca ccgactgccg gaagcgcggg
    22381 tgttgttcct ggtgtgctga tggctgtccg agatcggctt gatttgacac atgaacagca
    22441 attggaattc ttatttaccg ctggcgcttt cgggttagtc atcgcaaaca acgcttctat
    22501 cagtggtgca gaagggggat gtcaagcaga agttggttct gcaagtgcaa tggcagcagc
    22561 agctttggtt tgtgcaaaaa atgggactcc tcatcaagca gcacaagcag tagccattac
    22621 attgaaaaat atgatgggac tgatttgcga tcccgttgca ggcttagttg aagtcccgtg
    22681 tgtcaaacgt aatgctttag gctcttctca agcttttatc tctgctgata tggcattagc
    22741 gggtatcgaa agtgtcattc cgccggatga agtcgttgct gcaatgtacc aagtcggacg
    22801 tcaaatgccg tcgattttca aagaaacagc agaaggtggc ttagctgtta cgccaactgc
    22861 taaacgactt gcggaagaga ttttaaataa gagggcgtga taaagctcct taatttcgag
    22921 tattaagaga ttagttatct tcataacaaa aaacgaagag aggactaatt gcccttctct
    22981 tcgtttttta ttaatccatc aatttcgtat tttttacttc atcgatcgtt tttgttcctg
    23041 caagttgcat cgtgatcgac aattctttgt tcaggtgttc aaaaacagat gttactcctt
    23101 ctgccccacc tagattcaac ccataaatca ctggtcggcc aatcgcaact aagtcagcac
    23161 cacttgccag agctttgaag acatgctctc ctcgacggac accagagtcg aaaatcactg
    23221 gtacacgttt gttgactact tcggcaattt ttggcaatac ttcaaaggac gcaggacctc
    23281 catctagttg acgtccacca tgattggata cccagatacc atctgcccct gcagagatag
    23341 cgattactgc atcttctggc gattgtattc cttttacgat aactggaaga tgggtgattt
    23401 ctttgattgt tttgatgtca tctggtgtca agccttgttt tgcagctgca taaatttctg
    23461 cgattccttt tccttcgcca ttaccacttg cactttgttc gctatacgca gctaagttag
    23521 gcattggtaa tggaaattgg aattgattga tgacgtcttc ttcacggtaa ccaccgagcg
    23581 ttgaatctgc cgttaaaatg atagctttag cccctgcttc tactgctttg ttcaaaatga
    23641 actcattgaa tctgtcgtct ttactcatat ataattggaa aaactgcggt gcgcctggcg
    23701 ctgcatcggc tgcgtctttg attgtcgtat ttgcataagt gctgatggaa aagattgatc
    23761 cagcagcagc tactccttta gctgtatcag cttccccttt ttcatgtgcc aatccttggg
    23821 ccgctgatgg cgcttggata atcggtgtat ctaattcaat tccgaaaaca gatgtatgca
    23881 aatcggctga gtcgattccg cgtaatatcc gtggcatgat tttctttgta ttaaaagaag
    23941 tcgtattttc tttcatcgtc cactcatctt cagaaccacc gcgaatatag ccaaaagctc
    24001 ctgcttccat gcgctctttt acacgacctt ctagttaggc aatgtttaca atatcgattg
    24061 gatgttcttc attacttgta tgataagtca tagtagatcc ttctttcatc ttcttgatta
    24121 catataaatc atactaaact tacaaaaagt aagcaaacat ttactctcag atacttttat
    24181 cgctattctt tccaaataaa tcgacttaca agctgatcta cttcttggtt ttcatgaagc
    24241 atactatgag aggcattttc acctgtcact actttttcct ctatttcatt tccgcgttgc
    24301 ttcaacaacg catagaccgc taatgcactg tttaacggta ctgttccatc actcaagtct
    24361 gtttcatcta gttgaccagc aatcaagaaa aatcgagtgg ttataggaat attaccgatc
    24421 atttgctggt aatcttgata gcggttagaa acgacagcag gcccctttgc taactcatct
    24481 gtcagagact gcgcactatc atcgacaaaa tcattaaaag gcgcgccaat tgctgttaat
    24541 gtctgaactt gtggcaatga cgtatcctgt ccatacgttc ctaaatagcg tagtgcacta
    24601 actcctccca tggaatgccc cactatgttg actttatcta tgccgtagtt ttctttcaga
    24661 tacaaaagac aagttttgat ccattctgct tgattccact cgttattttt attatcttca
    24721 aacaatactt ggaccatcgg attgtctgct tttccagaca aatctcctgt tgcttgtatt
    24781 tgtccatctg ttcctactgt taaaaccaat tcttttactg cttgctgatt tttttccaaa
    24841 cgccgcaaca tccctttaaa ggaattttct gtcccgctgt agccgtggaa aaaaagtgtt
    24901 ggaatagtgg ttttttctat cactttactg gattctgccg ttttttcttt atcagaaact
    24961 tcagtagtat ttatcttcgt cgtctggcaa ccacttaacg caaacaaact gataaggact
    25021 aaagctgctg cagttgcacg tttgcataaa tttttgattg gttctgtcat acacctcttc
    25081 ctttccatat agaaaaaaga aagacttgaa aggccaatca tatgatcgac atttcaagtc
    25141 tctttattaa tcgattttat ctacttgatc gaaatcaagt tctgtactgg tttcacgtcc
    25201 aaacatatcg atgttgactt tcaatttttc tttttctccg tcaacttctg ttacttgtcc
    25261 ttctaatcca gcaaatgcgc cttcgatgat tttcacgact tcgccaactt ctacttctag
    25321 atcattttgt cgcaggctca taccgataga acgcaagata tgattgactt cttctggaag
    25381 taatggtgct ggtttgcttc cggctccgtg tgaaccaacg aatcctgtca caccaggtgt
    25441 gttgcggaca acataccatg aagcgtctgt catgatcatt tcaacaagta cgtatcctgg
    25501 gaatgtttta tgaacgattt ctttttcttt cccatttttg acttcagttt ctttttcttc
    25561 aggaacaacg acacggaaaa taaagtcggc cattttcata ctttgcgcac gagattcgat
    25621 atttgctttt actttgtttt catatcctga atatgtatgc aagacatacc agtttttttc
    25681 aaaagattcc attgaaggct cctcatttca ttgtaaaata aaaaaacctc agtacacccg
    25741 aagtttttct ttcgcttcat tatagcacta aaagtacgtt gtggctagcg agttatttta
    25801 aaatccagcc aaataagctt tggatggctg tatccattac gtaaaacatc aatccgaaaa
    25861 taatagaagt ttcgatgact actaacgtat ctttacggag ttgttttctg cttggccaag
    25921 ttacttgttt gatttcatct tttacgcttt ttagaaattt catgagacaa cctcccttgc
    25981 tactgtttat ttcgtttctt tatgtaatgt atattgatta caatatttac aaaacttatt
    26041 gatttccaaa cgttcgccgc tttttccttc actgactgat tttgtgtagt tgcgagaccc
    26101 acaaacggaa caagcgagtg ctgctttttt ctttgccatt tacttctgcc cccttgctga
    26161 gaatcagact tatacttcat aacagtatca cgtaactttt tacttgtcaa tttgtgaaat
    26221 aaactatcta ttgttttgga taaaattatg atatgattaa tttgaaatta agctaaaatg
    26281 agacaattgg aggtatagcg atgctattaa aaacacttgt atataagaaa aaagatctga
    26341 caaccgttac agagactagt acattagaag aagcattaaa aattttagaa acttccggat
    26401 accgttgtgt gccgatctta gattcttcag gtaatatttt ccgtggaaac atttacaaaa
    26461 tgcatatcta tcgtcataaa gcaaatggcg gtgatatgac gcttcctgtc actcatcttt
    26521 tgaaaaacgc tacaaagttc atttacctgg atacttcttt cttcaaagta ttctttacga
    26581 tcaaagagct tccttatatt gctgtccttg acagtgaaaa tcatttttat ggtattttga
    26641 cacatagtac gttgcttaat atgctctctc aatcttggag cgtagaacaa ggaagctatg
    26701 tactgacaat tgcttccaca ggaaagcaag gagatttggc tgctattgca aaaatcattt
    26761 caaaacacag cagcattgcc agctgtatta ctcttgatat cgaaaaagac gaatacattc
    26821 gacgtacatt gatcacgcta ccggctaaca ctgaagcgaa agtatgtgaa acgatcgtca
    26881 accacttaga gaaaaagaat tataaagtgg tagaaattga aaatttgcaa aaccaagaag
    26941 cataatcaaa aagcgaaaaa agaaaacagc taatctgctt tcttttttcg ctttttataa
    27001 ttagacacgc ttttcaaaat caagcgcgcg atctaaataa tacatcaatg gtgctgaaac
    27061 agccatgacg ataaactcac ttaatgcaag cgtgccatag gttgtccaaa atgcttggcc
    27121 acctgttgga actaacatat aagcaatcag tcccatgctg atggtaaaga agatcgtgtt
    27181 caatactaaa cgcatcttta catttttcac tttgttttgc aataaagctg tcaggcctaa
    27241 agaaagcaat gtttggccgc caccaaaaac cacatccatg ataccaaaac caaagaaggc
    27301 attatagacg atgaccccgc ctaaaactcc ccaaagcaat ttacggttaa agacaactaa
    27361 atgattcaaa ctttctgaaa tacgaaactg gatcggccct gaggatacag gcgcaactaa
    27421 aatagttaac gctagataaa gagccatgat gatgccattt acaacgatta cggataaccg
    27481 ttgtctgctt ttcgtttttt gcattttctc tcctcttttc tcctagtttt tttaacgcgg
    27541 gatggttgat gaaccgcggt tatgtgaaac aaacaataat tataacagac ttttcattta
    27601 tttcaatccg tcttatctgc ttttaaaaaa gcaaaagctt aaacaatgta aacgtttgct
    27661 aaaaatcgtg ggatatggta taaagtaagt gtaaggggtc ataagaattc ccagtaaagc
    27721 agacgaagta ggatctgcaa gaacagaatt gttgtgaaac ttaaataaat aaaaaaggat
    27781 gtgggaattt gagcaacctc ttactagaga acggtctagc aagcagctga agatctaagt
    27841 ggacatgccg aaccttggaa cttctcctta cgtaagtaat ggatcatgcg cttgctaggc
    27901 ttttttgtgt ttttcggtct tcggaccttt ttcattttcc tagacttctg ctataataac
    27961 caagaattaa ttttgtaaca gatttttttg aaaaaacaag tttctttcat tcaaaaaata
    28021 gaaaaagctt gctaattatt ggttaaccag caaacaggag tattaaaata tcttgtttta
    28081 ttgaatagca ggaggaaatc atgaaattcc attatcatat attgatcaat ccatcggcag
    28141 gcagcggaaa tggctataaa gtagcagaaa gaattttacc ggtattaaaa aataagcata
    28201 ttgactatac acttcattat agtgaataca aaggacacga tgctgagatt gctgaaactt
    28261 tggcaaaaga aacattgatt ccttggatag aagaagaaca gaaaacaatc gatactttcc
    28321 cccttttgat catcgtagga ggtgacggca ccttacatca ggtacttgat actttctatc
    28381 agatggaagt agaattccca gttgcttata ttccagcagg ttctggagat gattttgctc
    28441 gaggggcagg ccttccaaaa aatcccaaaa aaggacttca gctgatttta gcagctcaat
    28501 caccagaaaa agtccacata atggcttatg aagaaaaaat aagtgaaaaa aaaggaatag
    28561 ctgttaataa tttcggtata ggattagatg cagctatcgt ccatgcgaca aatcattctt
    28621 ccacaaaaaa gcgattgaac aaatacaact taggatcatt ttcgtattta ttctctattc
    28681 tccgtgcttt attcactcaa aaaggatttc caattctggt agatgcagga ggaaaacaat
    28741 taagtttttc aaacgcattt ttatgtacag caacgaagca tccttttttt ggcggaggaa
    28801 tcgcgattgt tccaactgct gatgcgtcta aaccagtcat tgattttgtc gtggtcgaac
    28861 gaatcaattt ctttaaaatc ttgtggctca ttcttttact tatacagaaa aaacaattga
    28921 aatcgaaata tttccatcac tacacaacaa acagattacg tatcgtttca acaacaccgc
    28981 aacatggtca agaagatgga gaagaaatgg aaaaacgacc ttttgatatc acaataacca
    29041 caactaaaca gttgttttgg tgttaataaa agaggttttg tcagaagcta catctggaac
    29101 accgtttatt cggaaaaaag gactgtgaca cgacttttgt cacagtcctt tttttactat
    29161 gcagttaatt ctttgcccaa ttgggttgcc atcgatagtt tctttcttta cccaaaataa
    29221 attggatcat tgaaaacacc gcagcaaaag caactaagac acaaccattg aaccaaaaag
    29281 attctgcaaa tgtttgattg taactgagtg tttcactgat caagttatta ttttgaacaa
    29341 accaatatgt tggtgtgaat gccgctattt tgctaaccat ttctggcaag tattctgctg
    29401 gtacaaacac cccaccgata aagcaactgc ctgtgataaa aatatctttg atcccaccgc
    29461 tggtttctga gttttttacc aatgaagtga tacaagccga aaagctaatg atcggcaata
    29521 aaaacaagaa agtatttaaa atatgatacc ataccgttat atcccacgag gtgtggatca
    29581 ctaacagaac cattagaagt aagaagccac tgaacaacag cagcgagtaa ctaatcaaac
    29641 taaaggttac tttgcgattc aagtttcgtt tggtaatggg cgcactctgg tttcgtttac
    29701 tgatctcttt gcgattaaat gctagattga tgacgctgaa accgctaaaa atggatagaa
    29761 acaacccata agacaagaaa ttaaaggttg tgcccgtcaa cagctttttc atccgctgac
    29821 tatatcccgc acttagctca acttctccag taaccgagag tgccatttgt gtctgttcca
    29881 tagctgcatc gattgtttta tcttcttctt gaaacagaat cagtgtttgc aaaaaggtgt
    29941 tcacttgctg tgtaacaact gttttagaaa aggcatctgg gcgactctgt atcttgatcg
    30001 tcggcatctt tcctacttcg acttgttcgg taaagtctgc aggcagatgt aagataatgt
    30061 ttacacgatt aaaataaaga gcatcatcga tttctttttg tgaggttcca tccaatgtaa
    30121 cgactgtttc cttgtcattc aaatatttac gaaggccatc gactacaggc gactcttctt
    30181 cactaatcaa ggcgattttc gcatcttgca gagaggtatt ttcaacatca atattttgcg
    30241 caaaaaagaa tgtggcaaca acagtgataa ttacacctat cagtaaattc gatttatttg
    30301 ctttaagcaa tgtccaaatc gttttataaa gcgtcataac gcacccctct ttccatccaa
    30361 gcatttccta acgcaaaaag gaaaataaat ccgatcaacc atagaagatt ggtataaaaa
    30421 ctagccaaat cagtgtagaa ataaagttta tacaaacttt cgctgatcaa gttgacgaga
    30481 tttaattgac caacaatcgg aatatgaaga tcaatccaat acttcacttg ttccgacccc
    30541 atcataccag caaaaaagct catcgcaatc gtcactgaaa tcaagatgct atccttttgc
    30601 accagattca tttttggtat caaattacca accaatgtac ctaacaaaat cgcacacaac
    30661 gaccccagag cggtaacaat catcaaccat tgccaacgtt caccaaagtc tacttgatag
    30721 ataaaacgaa agacagctaa cataatataa atctctgtca aaacaatcgt aaagcttgct
    30781 gccaaattag cgattgaaac taacgattgc tttctaggaa tcaaggacaa gcgaatacca
    30841 tttgacgatt gatttgcttg ctgatcctgt acattgcgga ccccccacat cgtcccgtag
    30901 agaatcgcca ttccaatcag agtgaagaaa taaaaacttt tgaaactcat attacgacct
    30961 gcatgaactt cttgaaaaga tacttcttgt tcaaaaacag tcatgatggg cgcgagatca
    31021 acgttctcca cttctgccac tttactcgaa attataccaa tacgctgtaa aaattgatcc
    31081 atgacgtttt tcatcaacgt ctgactcatt cctgcttgac ccacatggag cgaaacagat
    31141 gaaccatcaa tgagataaaa accagccaaa tcatctgcat ttagcttttc attcgcttct
    31201 acttccgata gttcctgtac ttcaaataat ggtttatcat tgacttcgac ttgttctaag
    31261 actgtggtaa aattttccga aagcgctgtt tgatccgctt tgattacaat tccagtatta
    31321 atcgtttcga gattgccacc ttgatcaatc tcgccaaagg ccgccataaa catcaatcct
    31381 aaaagaattg gaaaggccaa tgtccaaaac aacatggatt tatttcgcag cagtattttt
    31441 gtgcgatatt tataaaaatg ccaaaacatt atttcccctc ctctagtctc tcaaatcctt
    31501 gccagtaatc tctaaaaaga catcattcaa ggacgcttct ttggttgcta tttttccgta
    31561 actgatcttt tcttcttgta agattgtaag aatcggcaac aatactgtat ttagttcagt
    31621 agttgttact tggagctgac cttttttata agcgattcca tcagaagcta ttgttcgctg
    31681 acaacacgtt ttctgggagt aatgggatgt cgatcgtcaa acgatccgcc gtccgtacca
    31741 tatcttttag agattctttg gttcctttag caatcacctg tccttgatcc atgatcacga
    31801 tctggtcgca aagaatttct acttcttcca tgtaatgtgt tgtatagaca atggttgctc
    31861 cttgtcgatt cagctccttg atactttcta aaattttatt ccgactttgg gggtctacag
    31921 ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg ggcaatccca catgcgatgt
    31981 tcaaccgacg tttcaagcca ccactaagtt ctcctggacg aaacgaaaca tatttttcta
    32041 atcccactaa ttgaatcacc tcttcaatca aggctttcct tttctctttt tcggaaacat
    32101 ataaaccgca aaaataatcg atattttctt gcacacttag ttcgtcaaag accgcaacgt
    32161 cttgaggaac gaccccaatc attgccttga cagcataatt ttcaggagtc attgttgtcc
    32221 cgaacaattt aatggttcct ttgtcataat ttaacaaaga aagcatacag ttgatggcag
    32281 tcgatttccc actgccgttt ggtcctaaca gacctaagac ttctccttct tgtacttgca
    32341 gatcaaaatg attcaatgct acaaaatctc catagcgttt gactaattta tcaatttcga
    32401 taatcatcat gaaaaactcc ttccaaattt cttgttgatc tgactataat aaagtgcaag
    32461 aaaagaaact agtgacgatt ggctaaacca cacatgacat ttgtcacaat gaaggagtct
    32521 gctatgcata aatctcggct actcaacgaa actagctttc tactggttat ctcattgctt
    32581 ttgctggtaa gtcaaggatt cgttgctatg caagttatct atttattgat cgccgtttta
    32641 ttcactggtg tcagttattt actgcctaca aagccaaatt ggattttcca agttattcta
    32701 tttcttttat gtgccttttt acctgatctt gtcctgtttc tgccagcgac gatgcgagtg
    32761 atcgcccctg aagaaagcca ccttgattac ttgtttttgt taggtttttt gttgatttcg
    32821 acggttggta atcatccccc catcaaggtc gcctttgtcg taattttgct gtttttttcc
    32881 ttttacttac gaaaaaaaga tcaacgaacg accgatcttg agaaaaagta cattgtctcc
    32941 aaagatactc attgggaaaa acaacaagag ttatcggaac aaaataaagc attggccctg
    33001 tcacaagaaa cacaattagc cttgcaaatt gtggaagaac ggaaccgaat tgcccgagac
    33061 atccatgaca atgtcggtca tctgctgtca agtgcgattt tacaaattgg tgcgcttgaa
    33121 atgatcaatc aagaaccaaa actaaaagaa ccattagaaa atttaagtgc caccgttcac
    33181 actgggatgg atcggattcg tcaaagtgtc catgacctcc atgagacatc gatctctttt
    33241 caacactcct tagagtttct gatcgctgat tttccttctt ctgttacgat tgaaggaaac
    33301 ttgtttgaag gattgaatga aacgcagcaa aactgcttct taatggtcat caaagaagcc
    33361 ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg ttttacattt tcgaacgttg
    33421 ccggcctttt atcgcttgca aatcacgaat gatggcacca gcccacaaaa aaattctgct
    33481 cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag aacaaaaggg acaagtccat
    33541 attttccaag aaaaccagca atttcagtta acgatcattt taccaaggga gggacaccaa
    33601 tgataacagt agtcattatt gagatgatcc atttgtgacg aaatcgttac aaaccatttt
    33661 agaaagcacg aaagagatcc gtgtgttagg cattggtcat tgtgccaagg atgcgctagt
    33721 cttatacgaa acccatcgtc ccgatgtttt gctgacggac atccgcatgc ctaaacaaac
    33781 gggcatcgat gctgccaaag aaattttggc taaatttccc aaagccatcc ttttgctttt
    33841 gacgacattc aaagatgaag aatacatccg cgaagcattt tccatcggtg tcaaagggta
    33901 tttaatcaaa cagaacttgc aagcgattat tccttctgtc aaatccgctt ataatggaca
    33961 ggccgtattt ggtaatgaaa tcatcgagac tttcactcaa atgatgaaga ataaaccgac
    34021 gattgatagt catgcttatg cttcttttag tgaacgtgag cttgcaatca tcaaagaagt
    34081 agctgccggg aaaaacaata aagaaattgc agatgccttg tacttgagtg acggcactgt
    34141 tcgcaattac atcagccaat tactagaaaa gctagattta cgggatcgca cgcaattggc
    34201 tatctatttt tatcagcatt tgcaataagt cttatctaac acaaaaaaac ctgaatgatg
    34261 ctccttcgca tcattcaggt ttttttcaca tcttctattc aattgtcccg caaaccattt
    34321 cctcacgatt gaaagaatca aggattcgca gggctgccag gattcgttgg attgttcggc
    34381 gtgttaggcg gaaaaatagg cgccttgtct aacgtttttt ctagttttga ttcttcacga
    34441 tcgtctcgtt ctacatcagg actttcattc aatttgaatt ctttttccat ctcatctaac
    34501 tttttaaagt cattgccaga ttcttttgct aatttcgcta atttatcttc ggtttcttta
    34561 gccataaagt aacgcccccc ttttgatttc agcttagcat atcacactga aaaaacaaaa
    34621 gaaaacgcta accaacgatc atttttagct atttctcatc tttaaaatca agcatttttt
    34681 gccggtataa aatcgtaggg agaactgttt tccataccaa tcatcggatc tactaactgg
    34741 ttatcgatca cttctgctgt aagaacgaaa tctttagaaa cagcaggttc tacctcttct
    34801 ttcttttctt ctccaacaaa tgaagaaaac agatctggtt ccactgtttc cattacttgg
    34861 tttttcgttt cattcgtccc actgtcatct tctacaggta gcttttcttt tacaacccgt
    34921 ggctcttttg tatagttccc atcttcaaat ggatcatttc cgaccaaaga atcttcataa
    34981 gctgctagtt tggtccggag agtgatattc attttatcat tatccatgat ccttgatttc
    35041 aacgtagtca tccggcttgc tgattcattc gctacacaag tgacataggc ttgctcttcc
    35101 cctaacaaaa tcaacagttc cttactgcga gtcactgccg tgtagagcaa attacgctga
    35161 agcatccgct gatattgatg gaccatgggc aaaataacca tcttgaattc actgccttgt
    35221 gatttatgga ttgagcaaca ataagaaaga gtgattttat tccattcgtt tcttttataa
    35281 gtgacctcat ttgcatcaaa ctggataact aattcatcca ctttatcttc agaatctttt
    35341 gccaagatga tacccgtgat ttctcccata tctccattga atacattcaa ttcgggagta
    35401 ttgactaatt ggaggacttt gtctcctatc cgataaacgg tgtcgttcca atgtacttcc
    35461 ttttttccag gtttccctgg attgaatatc tcctgcatca ttttatttaa cgcatcgatc
    35521 cctgcaggtc cccgatacat tggtgctaat acttggatat cttgtgcacg gaatccctta
    35581 tttttcgctt tttccacaat tttagagatc aagggttcaa tttgataagc atcacttcgg
    35641 aaataggaac gatctttttg attctttgtg aaatcttttg gcagacgtcc ttctttgatc
    35701 tcatgggcaa gaggaataat actagaacca tcaccttgcc gataaatctg attgagttcc
    35761 attttgggaa tttgttcgat ttccaaaaga tcatggagta cttgaccagg accgacagag
    35821 ggaagctgat ctttgtctcc tactaagata acttgcatat tcgtcggaat cgctttgaat
    35881 aatgtgttag ccagccatgt atcgaccata gacatctcat caacaatcaa aagtccgcct
    35941 tctaattctt tcgtactgac tgaaggtgtt ttttcccgtc cattcagccc cagaagacga
    36001 tggatcgtac tggcaggcag acctgtcgtt tcgttcattc gtttagctgc tcggccagtt
    36061 ggtgctgcaa gtagaatagg aaaaatttct tgggtatatt ttgaaggatc caattccagt
    36121 ccgttcaact ctgcaaaaag attgacgatt ccgttgatca cagtagtttt ccccgtacct
    36181 ggtcctcctg ttaaaataaa tagaggggaa cggattgctt cagcgatagc ttgttcttgc
    36241 gaaggtccat actgtatgcc gaatattttt tcgatacgcc gaatattctt ctgcacttct
    36301 ttttcaggat aatggatttc ttttttacga ctgagaaggc gctggatcga attaccgatc
    36361 ccccattcag aaaagtacaa actgttttcg taaagattag tctcttcttg ttgtatcttt
    36421 ccttcttcaa caagttggat aattacagta gcaacctgat caggctggat ttcaattggg
    36481 cgacttgttt ctaaaatacg gatcgtttgc tgaagcaatg tctccgccgg tacgtatgta
    36541 tctcctgttt gaactgcatg ctgaaaaatc tgatgcaaga tagctgctcg aattcttctc
    36601 ggtgaatctg ctgcaatacc gatttgttcg gctagattat ctgcacgttt gaacccgatt
    36661 ccttctatgt cttcgactag ctggtacgga ttttcttcga tgatatccaa agactcgttc
    36721 ttataggcct ggtagatact gaaagctaac tgactaccga acccgtaacg attcagtccc
    36781 atgatcactt gatccatccc gtggtttagc cgaatcgtct cagcaagcat ttctcttttt
    36841 ggcttcgtca aaccggagat ttgttttaat accgaaggat cagcaatgat tttttcgata
    36901 gcatcttctc ccagcaattc tacaattttt tctgctgttt tcttcccgat tcctgggaat
    36961 ttttcgctgg aaagatacgc tacgatccca tttgcagttg ttggcttttc ttgctcatat
    37021 ctttcgagtt taagctgcct tccgtattta ggatgatcca ctaattctcc ataaaaacga
    37081 taagtctcat tttcttgaat atcgccgaaa cttccggtga ctacaatctc tttttcacgg
    37141 taatcagctg tggtttcact gatgtgtacc aaaagcactt tgtaaaaatt actaggattt
    37201 tgaaaaaaaa tcgcggcaac tgtaccaacg aaataaggca tttcttctgg ctgcatcgga
    37261 agccgcctcc ttcttctata gtaaaggttc tggtgctgtt tcagttccta aaaaatctgt
    37321 ttggttccat actttcagtt catatggcaa taatctgcaa ggctcttcag tctctaaaat
    37381 cgtcaaacta ctattgaaca atccacccat ttcacgcaac tcacttagct cttttcctgt
    37441 catccattga atggctgcag ttaaagaagc tccatgtcct acgaataaaa gtgggccatc
    37501 tttatgttgg gcaaccgcat ctgctacaac agtttcgata cgtgtgattg ccgattcaat
    37561 cgtttctccg tgaaaaggag aaggatcata cagatctaaa tgattacgca aattcggcag
    37621 attatccgga tatttctggt acatttcatc gatcgactga ccttctaaag tacccagccc
    37681 tagttctctt agcttatctg tataaaaaat ctctaccgga cgagcaagct ctttgttgat
    37741 accttctgct gtatcacgtg ctcgctttgc tgtactggaa taaattgctt taaaaggaac
    37801 atattttacc tttttcccaa atgctttgat ttcttcgtaa ctttgtggca aaagcggaga
    37861 atcgccattg ctcccttgaa aacgtctttc ctgattccat tgtgtcttcc catgtcgggt
    37921 aaaatatagt tccatacgca gcaaactcct gtctttcttt tattttactc tataataaac
    37981 tgtctaatcc agcttgtcat tttcatagtg atgcgtcaat tctaaattag ggaatccttg
    38041 ctggcgaagt gcttcataca ctatcattgc agctgtattc gataaattca atgagcggac
    38101 atgctcatca ttcataggga tgcgtaaaca cttttcttcg ttttcacgca taaatgtttc
    38161 tggcaaaccg gttgtttctt ttccaaataa aaagaagtgc tcttctccat cagcaaaatt
    38221 ttcgtcacta tatactttat gggcaaattt tgagatcaaa tgtagtttac gattacctaa
    38281 aaatgttaaa aaagcttcta aattactgtg gtaagtaata tttacatcat tccaataatc
    38341 caaccctgcc cgttttagat gtttgtcatc agttgaaaaa cctagtggct cgattaaatg
    38401 aagcggagta ttcgtggctg cacacgtacg ggcaatattt ccagtgtttg cagggattaa
    38461 tggttcaaat aaaacgatat gattcatcag gatcattcct ctcatattta tgttcgtttc
    38521 tattttctga caatttgatt tttgcataaa aaaaaacgta tcaactcggt gtcagtcact
    38581 gcgagtcgtt acgttagtga agctcttctc actaactttt atcagaacag gaacctgata
    38641 aaaaccaatg aaaaaacaac ttgttgctaa tataacaccc tcaacttttt tttgcaacct
    38701 ctactcatta aaaactgcta gaaaaacgtt ttctcttagt tccttttaat aattctatgt
    38761 caattgtaat cttcttcaaa ggattcttat ataagtctgc tttgattcgc tcttctacct
    38821 gccattctaa aggtgacatg gccaaaagat ctttttgatt ttcctctggt atctcaaatt
    38881 cataggttac acgctgacgt tcagttaatt tcattgcttc agcaaacttg gctactacac
    38941 gttcattgga ataactctgt ttttcaggtt gattcggata aaaagcctga cgtagttcct
    39001 ttaaataatt ttcttgtggc accaccttca acacttctcc atcttctgag agtacacgtt
    39061 ggaattcttg gtaatgagaa ggcgaaaaga tatttaaaac cgcgttgaat gtttgatcag
    39121 caaacggcaa attggtcaaa tcagctacac accaaaatgc ttcggcagat tgttctgtag
    39181 ctgcgtagac tccttctttt gaaatatcaa atccaacagc attttgaatc tttttcaatt
    39241 ttgaaagttc attcaagaag ctaccttctc cgcagccaac atctaatagc gagacttctt
    39301 caggtaaatg ctgcgcaata gtctcaataa cgggctgata catgccagat tggatcattc
    39361 tacgccttgg aacgaacatt ccttgatcgt attctgtttt aaccgcatgg gataaaaaat
    39421 aaagtgttcc ttttttggaa aggtcaaaac ggtgattatt tttgcatatc aagccattat
    39481 cagacttttt tacttcttct tggcaaaccg gacagcggaa cagctgatga ttttctgcca
    39541 aaaactggcg tcctcggtca atttttttta acatagttcc ccctcatttc tgttttatct
    39601 taccgttaga tgctcacttt ggcaactgct aaaaatatga tacaatgcct agaagaaagt
    39661 gaaagataaa ggagaagatt agatgatcaa agaattttgc gctgaaaact acacatctat
    39721 tcctctagca attgctagag gagccgatcg gatcgaattg tgtgacaact tagcggtcgg
    39781 tggcacaacc ccgagtactg gtgtgatcga agaaacgtta agttatgctg gggaaaaaga
    39841 tatccccgta atgacgatta ttcgtcctag agggggcgac ttcgtctata acgatatcga
    39901 attgaaaatc atgcatactg atttgattga agcaaagaaa ttagggacgg atggcgtagt
    39961 atttggttgt cttactcctt caggctggct agacgaagag gccttagaac tattgatcga
    40021 aacagcagaa gggttgcaga tcaccttcca tatggctttt gacagtattc ctgaagatcg
    40081 gcaattcgaa gcaatcgatt ggctggtaga acatggtgtt gaccgtatct tgactcatgg
    40141 cggtcctgct gacaaaacta ttgtagaaaa tttcccacgg cttaaagaat tgattgccta
    40201 tacagatggc cgcttaatca ttttgcctgg tggtggtgtc actgcagaga atgcagcaca
    40261 tgtagctaaa gaattgaacg taagcgaagt acacggaacc aaaatcgtgg atcttcagtt
    40321 ataatcttat aaacaaaaaa acatttgcaa caggcataat gcttattgca aatgtttttg
    40381 tttttttaca taaaatagcc cataaataaa gaagcaatat tgaaataaat cagtacactc
    40441 gtcaaatcgc tcaaagtcgt gataaaggga ccgcttgcta ctgctggatc aaatcctaga
    40501 cgatccatta gcatcgggat taaactacct gcaagattcg ccactgtgat tgcaaatagc
    40561 atagccatcc ctatgacaaa ccccaagata aaattatgtt tccaaaaacc tacgattaga
    40621 aaaatcgtga tccccgtaac agctcctgtg acaacgccgg tcaagacttc agccaaaaca
    40681 agtcgaacaa atccatgatc tttctcatca gaaatcgcaa gtcgacgaac agccacagct
    40741 agcgactggg ttccagcatt accggcagtt cctgtaatca gcgaaatgaa gactgctaaa
    40801 atactcgctt cacttaccaa gtcttcatag tgactgatta aagaagcggt cgacatacct
    40861 aaaaacaaca gagtgatcag ccaaggcaaa cgtcgagacg ctgcctttac tggattttca
    40921 ttaatttctt ccacattgac cccggcaagt cctgaataat cgctagcagc ttcatcatca
    40981 ataacgtcga tgatatcatc gactgtgacg attcctaaca aatgatcatc ataatcggta
    41041 acaggaagag ctaagaagtc ataatctcta aatgtttgtg ccacatcttc ttggtcgtcg
    41101 cctacatgaa ctgaaagcac tcgttcgctc atcagatcag aaatcattgc gtcgtcatca
    41161 ttcacgatta ggtcgcgcag agaaataacc cctactagct gaccttcttg attaacgaca
    41221 tagatgtaat agattgtttc agctacatct gcttcgttct tcagcacgta catcgcagag
    41281 cgaacagttt gattggctac gatcgaaaca aattcagttg tcatgatcgc gccagccgtt
    41341 tcatcctcgt aatggagaag ttccttgatt tcactggcat cgtctgccga catcaaactt
    41401 aaatatttag caatttgctt tttatccagc gtattaagca agtcaacagc attatctgta
    41461 tacatctcag aaagcatatc agctgcatag ctaggacgca tttcatctag gtattctttc
    41521 atatgttcgt tgtcttcttc aatcacatcg aacatatccg ctaattcttt aggcgacaga
    41581 taggaataga tcagctgcct gttctcttct gtaagagatt ggtagaattg cccctgctca
    41641 tagatatgca tctctaaaaa actgtttctg aatgcctgaa tattattttc ccttaaatct
    41701 tgagtcaact gggcaaatct ttcctctaat tcttgatttt catccaaacc aatctcacct
    41761 cgccttattc ttcaaaccgt ctcacaactg cctccatgtc tgcggctaaa ggctgcttga
    41821 actccagcaa ctcttctgta aatggatggt aaaaacgcag atcataacaa tgaagggctt
    41881 gtctttttat tcccagatcc attcgcccgc catacatatc atcaccgagc agggcacagc
    41941 caattgcgga aaaatgaact cttatttgat gtgtccttcc tgtatgcagc tggatatcaa
    42001 ctaacgcgat ttctgttagt cgcttctcta tccagtactc agtctgtgcc gaacgtcctt
    42061 catcagagac cattcgcttc aatagcgaag aataatctcg ggcgatcggc aaatcgatat
    42121 gtccatgtgc cgataaatct gaaagccttc cactgactaa ggcctgatat tttttcacaa
    42181 acttcttttc acgaagttgc atatctaatt ttgcgtgcgc aaatccatgc tttgcaaaaa
    42241 gcatcaaacc agatgtatcc cgatctagtc gcgtcaccac atggattact tggttttcgt
    42301 aaccttgttt tttataataa gcctttacac gattagccat tgtcccattt ggatggtatt
    42361 gggcaggaat agacgaaacg cctgctggtt tatttactac cagaacgtgt tcatcttcat
    42421 acacgatatc gatcggtgtt tcatccaaaa gtacggtttc atgttctcct tcagcaggaa
    42481 tcacaatggt taccttatca tccttagcta gagaaaacaa gacattttct acttgatcat
    42541 taactttgat ttgaccgcct tgaaatttta ttttcgctaa cagacccttt gagatccctt
    42601 tttcttttaa aaaatatttt acttgctgag aatgatcttt ctcataatcc catgtaaact
    42661 gcatatcaat cctcactaat aaaggcatct ttcacacgat gccaaaaatg catatgtcga
    42721 taagaagcaa aatggatccg ttcttctgct attcgataat aaattgagcg gatatttgct
    42781 tttgcgacat tcaattgatc aaccgttaca agataatctt ctgtattttc caattttatt
    42841 tctagccatt catcatgggc aatcacgatc ggagaaccca aagtacgaaa cactcgatta
    42901 ttcagtgaag caatctctgc caactgaaag gcattgatac taggatggat cacagcaccg
    42961 ccgacacttt tattatatgc tgtcgaacca gtaggcgtag aaatcgtcaa tccatctcct
    43021 ctaaaacttt caaacagctc gtttttgatg tatacatcgg ctaccatcgt acgattggcc
    43081 cgtttaatcg ttgattcatt cagtgctaaa aaatgctggt ccggtgtttc atccaaataa
    43141 ctgatccgaa catccagcaa gggataacta acactttgtt cccggttcgt tcgtaagctg
    43201 tctactagtt cttccagctc gtaatcccgc caatccgtgt aaaaccctaa atgacctgta
    43261 tgcacgccca agaaacgcac atcattcaga caatgactgt agtgatggaa cgccgacaat
    43321 aatgtgccgt ctccgccgac tgagatgacc aattctggct catgatcatc tcgttgaatc
    43381 cctgcttgtt ctaaaagtgc gttcaaacgt tctgtcactt ctatagtctt tgcttcttta
    43441 ttatgaacga tcgctacttt catcccctgc ctcctctctt tcgctttctt tcttcaaaag
    43501 cgttcgatag tagacatcat ctgattttcc tcttccatgg gagaataacc gctgtgcttc
    43561 ttggatttct tcacggatac tggacatctc ttcatccaac tgataggcag cttctgccgc
    43621 acgctgaagt cgttcactca tttcttctgg aaaaacgcct tgatatttat aattcagcga
    43681 atgctcaatc gttgcccaga aattcatcgc aagagtccga atctggattt ccgccaaaat
    43741 tttcttctca ccgctgatca gctgtacagg atactcgatc accagatgat aagaacggta
    43801 gccacttgct tttttatttg tgatgtaatc tcgttcttgg agaactttca tgtcttttct
    43861 tttacggatg atctcaacaa cttgatggat atcttctaca aactgacaca tgatccttaa
    43921 cccggcaata tcagacattt cttcttctaa acgtcccatt ggaatatgcc gtaattgtga
    43981 ttttgttaca atactatcga ctggcttgac tctcccagtg acaaattcaa tcgggacatg
    44041 tcgattttgt tcacggaact gtttgcggat cccccgcagt ttcactttca attctgatac
    44101 agtttgttca tatggtgcta aaaatgcttc ccaatctcgt tccatagctg atacctctac
    44161 ttcattaaca ttcattgttt attctaccat atatgcaaag ttttttcgta ctcttgattt
    44221 atgcattgac caaaaaaaga aaattaggca aaatagacaa aaaggagtcg atcaaatgac
    44281 acaaatgctt gaaatcgaat ataaatctat gctgacaaag caagagtacg agatattcat
    44341 cgctcactat caattaacag ataaagattt ccgtgtacag actaatattt atttcgatac
    44401 cgttgatgaa cagctgaaga aacaaaattg tggcctacgg atccgtttcg ttggtcatca
    44461 agctgaatat acattaaaaa cacctgctga aaaagggcgt ctcgaaacaa cggatacctt
    44521 tataacagaa gaagcagaag catttatctt cgaaaaacgt ctgcctcgtt caggcgcagt
    44581 ttttcaaaaa ctttctgatt tgaatatcga tcctgcttca ttaatccaaa ccggaaagct
    44641 tacaacaaaa cgggctgaat tccctattga agaaggactt ttagctattg atgaaagctg
    44701 gggagacaat ctacacgatt ttgaactgga actagaggta ggggatgcat ctgtgggaaa
    44761 aattgctttt ataaattttt taaaacgttt ttctttacct tatcgtcctg ctaagaacaa
    44821 gatccaacgt atgcttgaag ctaaaaatta gaaacctttc attttcacaa ggcacttgag
    44881 ttcatttttt tacttttttc tgttaagtta taggatgtga aagaatctag tcactagttg
    44941 tatagaatct attttggggg agattcatat gatcgaaatc tatttatttg ttaatccttt
    45001 aggggaatac tgtttcgaaa tggaacaaca gttattacaa tttatcgaag aagagtacgg
    45061 gacaccatca aaagaaaaga tgcaatttcg ctttcttcct ttggtcaatt tgcagacaat
    45121 tggggatgtc atgcaacaaa aaggaatttc tcagaacaat cttgaggaac gtaatcactt
    45181 attctcaatg acttattctg cagcattgga ctgcaaagcg gcgcagtttc aaggaaagaa
    45241 aaaaggccgc cgttttttga tcaaattgca agaagcagtc ggctgtaatg acataccata
    45301 ttctcaagaa cttgctgaat ccatatttga agaaatcggc ggcgatttga atatgtttaa
    45361 agaagatcgt cagtctgact tcgttaaaga agtattcttt tctgatcaaa aaattgctcg
    45421 ggaaatgggc atcacaaaac acccttctgc agtcgtttac aattatgcct acgaccgtga
    45481 ttttggtgtt ttagtagaag taaaaggtac aagtagcctt tggagaatca cagagctgtg
    45541 taaaacaaca gataactcat atcaagtttt taatggtgaa catttacata caaatgattc
    45601 tcagttccat tcaagaacta gccatttaca cttgctttct aattaaaaaa atacgtcgac
    45661 tcccttacaa gagagccgac gtattttttt cgtttctatt cgagaaaatc aaaaatagaa
    45721 agccttataa acgatcgatc aattcttcta attcatttag acgttgttca aacatcgaca
    45781 ttgcatcttc aatatatgca gcctgtgtca tatcaactcc tgcttttttc attacttcca
    45841 caggataatc gctgttacct gcttttaggt aagccaagta gttctctagt gcctctggtt
    45901 cctggtttag tattttcttc gccagtgctg aagcagcaga aaagccagtc gagtattgga
    45961 aaacatagta attataataa aaatgcggta tccgtgacca ttcgaattta atttctgggt
    46021 cttcttcgac tgctggacca taatattttg cattcaattt accataacta tcacttaggt
    46081 attcactagt caatggcaca cctttttcat cttccgtatg catgaaatgc tcgaattcag
    46141 cgaattgtgt ctggcggaaa actgttcctt taaacccatc caagtaatgg ttgagtacat
    46201 aagcccgtac acgagggtct ttttctgttt ccaataaata ctccgttagg atattttcat
    46261 tcgttgtcga agcaatttct gctaaaaaga tggagtagtc gccgtacaca taaggctggt
    46321 tcgaacgagt gaaataacta tgaacactat gtcccatttc gtggacaagc gtaaatagct
    46381 gatccagcgt atcatgccaa ttcaataaaa tatatggatt tgtgtcatag cttcccgaag
    46441 aataagcatc gcttcgtttc cctttatttt cgacaacatc gatccaacgt tcagagaatg
    46501 ctttttctac gatggccatg tattcttcac ccattggttt cagtgcttct aaagcttttt
    46561 cttttgcttc ttcgtacgta aaggtaattg gagcttcccc taagaccggt gtataaagat
    46621 catacatgtg cagtttttcc acttctaata aacgtttccg taattccatg tatcgatgta
    46681 acaaaggcaa atgcttgttt accacgtcta ccaaagtatc gtatacactt tcaggaatat
    46741 gattattgct caaagacgct tctctggcag agctgtaatt acggactttc gctttaaaat
    46801 tatgtccttt tatatgtgtg cctaaagtag aagcaaatgt atttctaaat tgttcgtaaa
    46861 cactgtacaa tcccttaaat gctgcttcgc gcacccttcg atccgtgctt tctagcaact
    46921 gaccatacac gccatgagat aattggacta tttcaccatt ttctccttca atcgttggaa
    46981 aaactagatc tgcattattc aaaacagcaa atgtatcact tgaagcatca aagatttcac
    47041 ctgctccagc aagaagagat tcctgctcag cagataagac atgggctcga ttatctacta
    47101 tttgctggat ataatggcga tagacttcca attttggttc ttctttgaaa tattgccaaa
    47161 tctggtcatc tgacaattgc aatatttctg gttcaaacca ggaaacggct tcactaactt
    47221 tcgaaaacag actgcttgct cttgcataaa gcgcttggta atctgtattt ccagtgtctt
    47281 gatcgttttt aaggtgcgca tatacataaa tgacttcagt ttggcgataa accctcaata
    47341 cgaattcaat cgcatttaaa aattgagaag cgccttgatc aagtgttcct ttgtgttttt
    47401 cagattgttt taactcttct gataattcca aatatttctc atcaaactct tggtcgcttg
    47461 aaaagatctt ggtcaagtcc caagttaaat tttcaggcaa ttcttctcgt tttggcaact
    47521 gctttacttc catgaaatcc actccttttc ttcccttagc tctatctatc aaaatagatc
    47581 atagtctaac atccacatgt cacagcatct aacttttcta ctcattcatg tgtctgcttc
    47641 catcaatttt agcataacta aatcttgttt tacatagaaa accgattcct agcctatttt
    47701 tatacttact attttttcaa agaagacaag tgtatgcatt cgttaaaaaa ctgctgatag
    47761 accatctctt catcaatcat aggaaaaagc cattcccttt tatgttcttt tatttggcaa
    47821 agccatgagt tgaaatcagg aactttctgg ttttccaagg cttcttcgta caacattcga
    47881 taaagaaaaa cctgttcttg taaataaaag aaaaaccgac ttttttgata gatccacgat
    47941 gatagatgca aaagatgttt atgacgcaag tagcattgtt cttgtatgga tactgtattc
    48001 ttttgcttgt gaataagttg gcgtgtcagc catttcttcc catcttcact cactttttct
    48061 atttttttca tttggttcat tttaatttcg ttactagtga atatttcttt aaggtcccta
    48121 ctagaaaaag tccagcagct actgcaaaag gaaatatgcc ctgatacagt ctctgtaata
    48181 tgatgataca aataaagctt ttgtttcttg agatcagctt tccagcaatg cactcctctt
    48241 tttctattat agtagcagca acttttttct atcaatgaga attgcgattg tccaagaaaa
    48301 gaattaccaa gtatccacca tacttggtaa ctgttattca aataattttg ggttctttca
    48361 ataaatctct ggtgagacag tctagaacat tggatttcta ttgctagatt cgccaacaaa
    48421 atatccggcc tttgccgcaa cctcggcaaa taggcttcca aaaatactgg ttctactgac
    48481 tgtcccagcc aatccatgaa gcattccttt aactgtaagt gctcttttga ttctctttca
    48541 ctaaagaccg aacagttatc tgatttttga tgggcaaaat gagcacattt tttctttccc
    48601 tttttcaaaa tcactctttt tcgacagcca cgacaataat atttctttcc tttttctgca
    48661 tgtttagcaa aacagcactt attatattca ttcattgcaa gcagcatttt tctccctctg
    48721 aacttattta cgtctaagaa tttatttaca cgaaaaaaga gggcgtgaaa aagctattct
    48781 gcatcaagta ataagaacag ctaaacaaaa atagttccca atatttttcg tttggttggg
    48841 cttgttaccg cagatgcaag cttttgaaca catttatacg aaaaaaagac tgcgacacaa
    48901 tttttgtcac agtctcttac tataatgctg atttatacaa aataaaattt cgttcgctcg
    48961 atagcattac gcgccatcag acattgtcca tattcattca atgtttctgg tgtacgatcg
    49021 ctcttttcag caaactccaa aattcgagca atctgattct ctacatccgc ttggttgaga
    49081 ttttccatcc agaagtgaac gactaggtaa tagcgctctt cgaataaata caaatcagtc
    49141 caagcagact ctagttcgac atctgttgca agttggatca cttgttcaaa atcttcaaaa
    49201 gcaaaagttg cttgtctttc ctgttcttct agggcgcttc cagataattc ttcctccgga
    49261 tcgctgccaa taatctgctg acgaagaaag tcactcacat cttctgaatc aacagtagaa
    49321 tcttctgatt gagaaatttc ttcatccgga agatttttac tgataaacag ttctaatccg
    49381 tctccttttg gcaaaacttg gaaagtgaca gcttcgcttc ctcggaactc ctcttcgata
    49441 tcaacttctt ccaaaatact ataaaagaaa ttttcgattt ctttgtgatt gccaagtaaa
    49501 tccaaaaatg aaacgccccg ttcctctaaa tcttcatgac caattagtac acggatcgta
    49561 ttttcattaa tatgttccat ttccattttg ctacacctca ctttgccaca atgtttaata
    49621 tagattcatt gtagcgaaat cagcttaaat gtaaagaaaa aaaatctcgc tgttaagcga
    49681 atttaataaa accagcggat ttttcaacct ttcaagctat cttatttaac tataacattt
    49741 ttggcagacg aatactatat agccgacttt tcagctaatt ttccctctct atttttcgtg
    49801 caatcatcat cttctactac ctttttatac atctaatcaa gaatactttt tgtaaaaaca
    49861 aaaaaacttg gaaaaactat ctttgtaata gt
//
LOCUS       DAFLWQ010000011        45063 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.012, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000011 DAFLWQ010000000
VERSION     DAFLWQ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.012"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(2..1012)
                     /locus_tag="L1V16_000648"
     CDS             complement(2..1012)
                     /locus_tag="L1V16_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBN1275011.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1192..1536)
                     /locus_tag="L1V16_000649"
     CDS             complement(1192..1536)
                     /locus_tag="L1V16_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBN1275012.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1529..1963)
                     /locus_tag="L1V16_000650"
     CDS             complement(1529..1963)
                     /locus_tag="L1V16_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HBN1275013.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2101..2838
                     /locus_tag="L1V16_000651"
     CDS             2101..2838
                     /locus_tag="L1V16_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1275014.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2831..4042
                     /locus_tag="L1V16_000652"
     CDS             2831..4042
                     /locus_tag="L1V16_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1275015.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4246..5028
                     /locus_tag="L1V16_000653"
     CDS             4246..5028
                     /locus_tag="L1V16_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HBN1275016.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5098..5760
                     /gene="trmB"
                     /locus_tag="L1V16_000654"
     CDS             5098..5760
                     /gene="trmB"
                     /locus_tag="L1V16_000654"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBN1275017.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5858..7612)
                     /gene="ade"
                     /locus_tag="L1V16_000655"
     CDS             complement(5858..7612)
                     /gene="ade"
                     /locus_tag="L1V16_000655"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBN1275018.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7744..8673
                     /gene="tadA"
                     /locus_tag="L1V16_000656"
     CDS             7744..8673
                     /gene="tadA"
                     /locus_tag="L1V16_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBN1275019.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8630..9679
                     /locus_tag="L1V16_000657"
     CDS             8630..9679
                     /locus_tag="L1V16_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HBN1275020.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9676..9954
                     /locus_tag="L1V16_000658"
     CDS             9676..9954
                     /locus_tag="L1V16_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBN1275021.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            9929..10399
                     /locus_tag="L1V16_000659"
     CDS             9929..10399
                     /locus_tag="L1V16_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBN1275022.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10416..10718
                     /locus_tag="L1V16_000660"
     CDS             10416..10718
                     /locus_tag="L1V16_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275023.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            10735..11106
                     /locus_tag="L1V16_000661"
     CDS             10735..11106
                     /locus_tag="L1V16_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HBN1275024.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            11078..11437
                     /locus_tag="L1V16_000662"
     CDS             11078..11437
                     /locus_tag="L1V16_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275025.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11609..12616
                     /locus_tag="L1V16_000663"
     CDS             11609..12616
                     /locus_tag="L1V16_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1275026.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12641..13825
                     /locus_tag="L1V16_000664"
     CDS             12641..13825
                     /locus_tag="L1V16_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBN1275027.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14262..15845)
                     /locus_tag="L1V16_000665"
     CDS             complement(14262..15845)
                     /locus_tag="L1V16_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBN1275028.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(16423..16566)
                     /locus_tag="L1V16_000666"
     CDS             complement(16423..16566)
                     /locus_tag="L1V16_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HBN1275029.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16789..17268)
                     /locus_tag="L1V16_000667"
     CDS             complement(16789..17268)
                     /locus_tag="L1V16_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBN1275030.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17341..17625)
                     /locus_tag="L1V16_000668"
     CDS             complement(17341..17625)
                     /locus_tag="L1V16_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275031.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17703..17897)
                     /gene="ssrS"
                     /locus_tag="L1V16_000669"
     ncRNA           complement(17703..17897)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="L1V16_000669"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(17969..19255)
                     /locus_tag="L1V16_000670"
     CDS             complement(17969..19255)
                     /locus_tag="L1V16_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBN1275032.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19393..20064
                     /locus_tag="L1V16_000671"
     CDS             19393..20064
                     /locus_tag="L1V16_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBN1275033.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20030..20518
                     /locus_tag="L1V16_000672"
     CDS             20030..20518
                     /locus_tag="L1V16_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HBN1275034.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20531..21478
                     /gene="prmA"
                     /locus_tag="L1V16_000673"
     CDS             20531..21478
                     /gene="prmA"
                     /locus_tag="L1V16_000673"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBN1275035.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21479..22243
                     /locus_tag="L1V16_000674"
     CDS             21479..22243
                     /locus_tag="L1V16_000674"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBN1275036.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22476..24689
                     /locus_tag="L1V16_000675"
     CDS             22476..24689
                     /locus_tag="L1V16_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBN1275037.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24700..25146
                     /locus_tag="L1V16_000676"
     CDS             24700..25146
                     /locus_tag="L1V16_000676"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBN1275038.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25317..26576
                     /locus_tag="L1V16_000677"
     CDS             25317..26576
                     /locus_tag="L1V16_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HBN1275039.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26665..27612)
                     /locus_tag="L1V16_000678"
     CDS             complement(26665..27612)
                     /locus_tag="L1V16_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBN1275040.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28006..29298
                     /locus_tag="L1V16_000679"
     CDS             28006..29298
                     /locus_tag="L1V16_000679"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBN1275041.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29313..31082
                     /gene="aspS"
                     /locus_tag="L1V16_000680"
     CDS             29313..31082
                     /gene="aspS"
                     /locus_tag="L1V16_000680"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBN1275042.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31191..32066
                     /locus_tag="L1V16_000681"
     CDS             31191..32066
                     /locus_tag="L1V16_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1275043.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32332..34215
                     /locus_tag="L1V16_000682"
     CDS             32332..34215
                     /locus_tag="L1V16_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBN1275044.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34290..34574)
                     /locus_tag="L1V16_000683"
     CDS             complement(34290..34574)
                     /locus_tag="L1V16_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBN1275045.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34564..35298)
                     /locus_tag="L1V16_000684"
     CDS             complement(34564..35298)
                     /locus_tag="L1V16_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBN1275046.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35427..36050
                     /locus_tag="L1V16_000685"
     CDS             35427..36050
                     /locus_tag="L1V16_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBN1275047.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36242..37363
                     /locus_tag="L1V16_000686"
     CDS             36242..37363
                     /locus_tag="L1V16_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBN1275048.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37370..40498
                     /locus_tag="L1V16_000687"
     CDS             37370..40498
                     /locus_tag="L1V16_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HBN1275049.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            40517..43711
                     /locus_tag="L1V16_000688"
     CDS             40517..43711
                     /locus_tag="L1V16_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HBN1275050.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(43857..44564)
                     /locus_tag="L1V16_000689"
     CDS             complement(43857..44564)
                     /locus_tag="L1V16_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBN1275051.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        14484 a         7982 c         9431 g        13166 t
ORIGIN      
        1 tttattttga tgaatcagtt gtttcttcag ttgaagattc ttttgttgaa tcagttgatt
       61 ttgtgtcaga actctttgtt gaagctgtag tttcacttga gtctttcgta cttgatgaag
      121 ttgttgtgaa tgcactcaac acattttcaa aggcatcatc tttgattttt acatttgcat
      181 cttttaattc ttcaccgatt actttagttg tgaatgcatt gtcacttagt ttagtttcag
      241 tagcgatatc ttttagttga tctttgtatt tatccatgtc attgccttta ttttggtttt
      301 tcaccatttt gacaacgtag tattctgtcg cataagaagt aggatttgtt gtagtaataa
      361 catcggagat ctcaccgtct ttcaatttga aagctgcttc ttttacttct gcaggaatag
      421 ttgttgtcgt tgagtcgaat ttaactttac cgccatcttc ttttgtctct gtatcagttg
      481 atttgtcttt ggctaattta gagaaatcat ctccatcatc cgctgatttt ttcacatctt
      541 ttgcttcatc ttcacttgat aatttgatga tttgtgcttc tacttctgga tggaaagatt
      601 tccaagcagt tttcaaatcg tcatctgtaa tatctacgtg agctttcaag ccagcttcaa
      661 aagctaaatt gttacgaata tattctttat aagtatcttt cgtatatcca gcagcttcta
      721 attgtgattc aaaagtatca cctaatgatt tcgcttgttt gtcgtattct gcatccactt
      781 gcttatcggt tactttatcg ccatatttgt tattgaatac tttataaatg atcatccgtt
      841 gtactaagga ttggttcgat gattcaagtt ttgcttcatc atagaaatca gatacagtga
      901 tcgttccgcc tttcatcgtt gcgatatctt tattagtatc gcctgaacaa gctgctagag
      961 ttaaaacagc caacgcacta gtagctgcca aaataattga tttttttttc attaaaattt
     1021 gcactcctgt aattagttat tatttttata tattaactat accatatccc atttccttta
     1081 aaaacgttgt cgtggtagtt tcaaacaaaa ttcaaaattt catcacattc ctaggaaata
     1141 cgcaaacttt tctcacttat atagttaaat ctgttgagaa aataatcatt attatatttg
     1201 ttcaggatac tctggcagat cagcttttag tttttctact tgttcattga tttgtgtgat
     1261 acgtggttcg gcttggaatt taaaatcttc gatatctttt ttgattgctt cttggaaagc
     1321 aggaatcaca gattcagctg tttcttttgt ttcgatcaat gcgcttttaa aatgattcag
     1381 gctgttattt aaatcatttg tcagagttgt tgcttcttcc aattcttcga tcagtttctt
     1441 tcttgtttca ttcccgctcc tgggcgccaa taacagacct ccgacagtgc cagcagcagc
     1501 tccaaataac agtcctttga aaaagttttt aatcatcgca ggacacctgc tttacgattg
     1561 tttcttgaat agcttttagt tcttccgatc cataactatc ttgatgattg acaaagtgaa
     1621 tagaaaaatc atcctctttg ctgtagcgag ggactaaatg gatatgtgaa tgaaaaacag
     1681 attgataggc tagttcacgg ttgttattca agatattaag acctttcatt tctggaaaag
     1741 ctttttccaa tgcttgagca atcttaggca cacgcgaaaa aacctctcct gcaagttcgg
     1801 gatcatattc aaaaatatct gctacatgac gtttaggcac aactaatgtg tgtcctttcg
     1861 ttgcttgaga gatgtctaaa aaagcataga ccttgtcgtc ttcatatatt ttatagcttg
     1921 ggatttcttg attgatgatt ttgcaaaaaa tacagttttc catataaaac atcctttcta
     1981 taaagaataa atacttcagc ttaactttac cataagttaa agctattgta aggaaaaaaa
     2041 caaaataccg tcattttctt cgtggtataa taaataaaaa taaatggcgg aggaaaaaga
     2101 atgagtttaa ttatcgatca tgtcacaggg gggtacggac atctccctgt gttaaaagat
     2161 atcagtttcg atgtacagcc tggagagata gtagggttga ttggactgaa cggagcaggg
     2221 aaaagtacga ccatcaagca cattatcggt ctgctggaag cttcaaaagg aacgatagaa
     2281 atcaatcatc tatccttaaa gaaaaatacg gaagaatatc gcaaacaaat tgggtatatt
     2341 ccagagactc cttctttata tgaagaattg acattgagag aacatatcga agtcactgcg
     2401 atggcctacg atatacctat ggatatagca atgaaaagag cagaaaagtt gttggagact
     2461 tttcggttat ctaatcgtct tgactggttc ccagctaatt tttcaaaggg aatgaaacag
     2521 aaagtgatga tcttatgcgc ctttttgatc gagccttctt tatatatcat cgacgaacca
     2581 tttttaggct tggatccact agctatcaat gcattgcttg aattgatggt agaaatgaaa
     2641 aaagaaggag ccggtatttt gatgtctacg catattttag ctactgcaga aaaatattgt
     2701 gatcgttttg tggtcttaca taacggagag atacgagcag acggttctct tgagatgttg
     2761 agaaaagaat ttcagctgcc ggattcttct ttggacgaaa tctatattgc tttaacaaag
     2821 gagcaggcac atgagtagtt tttttcaaaa acgtttagca agacatcaaa agaaaatgat
     2881 gaaatatatg cgttatgtat tgaacgatca ttttgtttta gtttgtcttt tcttgattgg
     2941 cggtgtggga ttatattatt ctaattggtt gaaaaccctg cagccaccgt ttgcaattgg
     3001 agggctcata atctctgtat tttggatgct ctgtttattc gtgggtaaga tggctacttt
     3061 tgcagaggca gcagatattg tttttttact tcctaaagaa aaagaaatgc aaacctattt
     3121 ggaacgagct tttcgctatt cttgcatttt tccgttgatc tttttgatat tggcatgcgg
     3181 attggccatg ccattagtgg tggttagtac ggagcaatcc ttttcgatgt ttttcgtcta
     3241 tctgatcata ttatggagtt tgaaattcag tcatctgcaa atcaagagag cagaattgtt
     3301 tcgactagat caacaagtta ttcgttattg gaaattaggc tggttttttt cttctctgat
     3361 ctttttgttt ctatcatttt attggctaat atgggcagga atagcaggtg cattagtaca
     3421 ggcaagtcta tattactggt ttttgtggaa gcaacaagaa aaaggattgg attgggagaa
     3481 aatggtgcat gtagaagaac ataggttgca tcagatctat caatttatca atttattcac
     3541 agatgttcct gaaattacgg caaagatcaa aagaagacgc tatttggatc ctatattgac
     3601 tcatattaaa agagaatcaa aaaacactta tctttacttg tttgcaagaa gattggcaag
     3661 aggttctgat tttagtggtc tttatttccg attagtaatt ataggtgggt tattgattgc
     3721 cggagtagtc gacttttatt ttagtctgat tatcggtttc ttatttttat atttgatcgg
     3781 tttccaactg ttacctttag cgaaccagtt ccgctatatg gttctcgttc agctttatcc
     3841 aatccataag aatcagaaga agcaggcgat tcagtatcta ctcacatggg tattaattat
     3901 cgcgtcggtt atttttggtt tgattgctgc agtcgtatta gatgggcagc agcgatgggt
     3961 tccgctagcg gcttatttga ttgttactat gctctttgtt aaactatatg taccaactcg
     4021 tttgaagaag atgtcagact gaaaacaaag ctgtgtaggg taaaaatgag aatgaaaaat
     4081 agagcgttga cagtaagaat gctgttcgtt ctattttttt tgagaaaagc tggttttttg
     4141 aatggcaatt aaatgaaaaa gaacgtatat gtgcttgacg tgtagtgttc aggcgactag
     4201 aataataagt actgcaaaac aaagagtaag aggacgggag aatgcatgat ggagtttcag
     4261 ttagaccaag agtggcggtt acgtcccatc aaaggcgaca caggaaaaac atacataggc
     4321 atgcgtgatg aggacaaagt ctttattaaa cgaaacacga ctccgatgtt ggctgctctt
     4381 tcaagggaag gaattacacc aaaacttgtt tggacaaaac gaacggggaa tggcgatact
     4441 ttgacagcac aagagtggct ggaaggtcgc ttgctgactc ctaatgagat tggtcaaaga
     4501 aacgacgtga ttgatgtttt gtaccattta catcattcaa attctcttaa aaccatgctg
     4561 acccgtatcg gtggtcgtgt catgacgccg gagaagatgc tgcaaaaata tgaaaaagaa
     4621 ttaccggaag aactccagaa aaatcaattt ctgcaaattg tccatcgttt tcttcgtgag
     4681 cagatcccgt caatagataa ggaaaactta tcagtagtac acggagatgt aaaccatcgt
     4741 aattggttag tatgtaaaaa ttatttatat ctagtcgatt gggattcaat catgtttgca
     4801 gaccctgcgg tggatattgc aacgatttta ggaaattatg tgccactgtc tagctggaat
     4861 cagtggctga tcagttatgg catacgcccg actgacgaaa tgcttgaaaa atttcattgg
     4921 tatgcggcca tgaatttgct ccaagaaatc accagatatt gcaaacgtga agatcatcga
     4981 cggatgaacg aagaaatttt acaattaaaa cgaattttca gtggctgagg tttggcccaa
     5041 actctgcgga gatttggcca gaccttttta attagaggaa aggaatggag ataaataatg
     5101 cgtgtccgaa atcgtccggg agcagcggaa atgttagcgg ctcacccgaa ttttgtaatt
     5161 agtgatccaa cattgtggaa gggaaaatgg aatgaattgt ttgaaaacga tcatccaatc
     5221 cacattgaga ttggtatggg gaaaggccag ttcatcactg gaatggcaaa agcccatcct
     5281 gaaatcaatt atattggagt agaaatgcag gtcagtgttg tttcgattgc actagacaag
     5341 ttgatcgaac aaccgcttcc taacctgaaa cttctacatg tggatggatc agcgttgaca
     5401 gagtatttcg ctgacagcga agtagatcaa atctatctga atttttccga tccatggcca
     5461 aaaaaacgtc atgaaaaacg gcgattgaca tataagactt ttcttgctgt agatgaacag
     5521 attcttcgtc caaatggaga aatccatttc aaaacagata atcaaggatt gtttgagtat
     5581 tctctggcaa gtttttctca atatggcatg atcctcaaac aggtatggtt agatttacat
     5641 caaagtcaat ttgaaggcaa tattatgacg gagtatgaag aaaaattttc ttcaaaaggt
     5701 caacgtattt atcgagtaga agctcaattt caagataaga ccaaaaagaa aagtctgtga
     5761 aactaacttt ctgctttcat aaaaacatta atatccataa ataaatccca gaaaatgaac
     5821 attacagatg taatgtattt tctgggattt atttgattta aaatgtattt atttcatcgg
     5881 tttttccaca aggtggaatc aattggaagc gagaaaatga aaataatcct ttgtcggtga
     5941 tcttcaattc gggtatgaca gataatgtta agaaagaaag tgtcaaaaaa ggatcaaagg
     6001 ttttagctgc tcctagttga tgtgctttag ttattaattc attcaactgt tcatagacga
     6061 tcgaaaaagg ttcctgtgtc atgattccgc ctataggaag agaaacacaa gctatttcct
     6121 gctgattgtt gacaacggtc atcccgccac ctttttgaat caaaagatta gcagcataca
     6181 gcatatcctc gtcgtttgtc ccaacgacaa ctagattatg cgagtcatgg gcaatcgttg
     6241 tcgctatcgc tccttgtttc agctgaaatc ctttcactat gcctaatcca atgtttcccg
     6301 tttgatggtg acgctcgatc accgcaatct ttaattggtc tttttcgatt gaaggaatga
     6361 atcgttcgcc ttgtcggtcc actttttcta ccaaatcttt agtcactaga ctattcggga
     6421 taatttcgat cacatgggct tgtgaagaag aaagaagcag ctctaacgaa tgtggattta
     6481 atggttgagc gtttagtttt ggcagacaac acgtatatga atttgaatga tcagcaaata
     6541 aatggtcttg gagttgccca gattgaacaa ctaatgttcc cttatagaaa acttcatgaa
     6601 ttggcagctt ggtaagatcg tctgttaaga agaaatcagc ttgataccca ggggcaatcg
     6661 cacctagtgt tttcaaatca aaacattctg ctgcattcaa tgttgccatc tgaatggctt
     6721 gtaatggatc gattccaagt gcaatagctt gacggacgat atgatcgatt gatccttctt
     6781 ttactaaatc attgatcagt ttatcatcgg tgacaaagaa gcatcttctt gaattttcag
     6841 gtgtgatcgc cggtagtagc gatgccagat cttttgcaac ggtcccttct cgaaccatta
     6901 aatacatacc aagatccaaa cgttctttag cttcttttgc agttgtagct tcatgatccg
     6961 tccgaatacc tgctgcagga taaacattta actcttccat gccgatacca gctgcatgcc
     7021 cgtcaatttt tttcttatgc tggtgcatca attggatctt ttctaggatg tctgtttcat
     7081 tatttgctac tgcttgatag ttcatgactt cagctaagcc taaaacttcg ggtttttgta
     7141 aaaaaggggc taattttttt gcatttaaat ttgcaccatt ggtctcaaaa ggggttacag
     7201 gtacacaaga aggtagcata aaaaagatat tcatgagtgt ttgtcttgca tcttctatca
     7261 taaactcaag acctgtactc ccagcaatgt ttcctatttc atggggatct gtcactacag
     7321 tagtaactcc atgaagcaag gatacttttg aaaattcgct tggtgataaa agtgagcttt
     7381 cgatatgcac atggccatcg atgaatcctg gcactagata ttgcccatta gcattatgta
     7441 cgctttttcc ttcgtattca ccgattccta cgatcattcc ttcgcagatt gctacatctt
     7501 tttccatgat ttctttcgta aagacgttga cgatcttagc atgcttgatc actaggtcag
     7561 caggcttttt tttacttgct acttcgatat atttccttaa tgttgtttcc aatggagtgc
     7621 ctcccaagat aaatttttat aagtataaca taaattcggt ttttgccaat atttttttgt
     7681 aaattcattt tatttgaaac aaaaagatca aaaagacgta tgttttttgt ggaggggaga
     7741 ataatggaaa taaaacgatt atcggatcaa atgataagtg aaagttttgc caaacatgcc
     7801 caagacgtat atatattgcc agcttcagaa gtattttaca tctattttcg ctatggaaaa
     7861 aaacgaacat tctggaagaa agtctcttcg gcagatggac agcaactgat ctcaagattt
     7921 aagtatttgg gacagatgga tatcggagaa aaaagaaaag ctcagttagg tgcatttact
     7981 tattctttag aaaaacagga agttcgtctg cggttgtctt ctgtaggaga ttaccttcaa
     8041 cgagagagtt tagtgattcg gctattatac ggtacttttg aaacacccca tcgttgcttt
     8101 agttctcgag attttgcaac tattttacag aaaaccgtca gacgtggatt ataccttttc
     8161 agcggaccag tcggatcagg caagacttct ctaatgtatc ggttggcttt ggaagaaaaa
     8221 ttgcaagtga ttactatcga agatcctgta gagatagaag aaccgttttt tctgcagcta
     8281 cagatcaatc cgaaaatagc acagacttat gatacacttt tgagactcgc attacggcat
     8341 cgtccagact tgctaatcat tggcgagata agagatgaat caactgcaca tgctgcggta
     8401 agagcagcac taacagggca ccgggttttt gcaaccgtac atgcacgcaa tcttgaaggt
     8461 acattggtca gaatccatga actgacaaag aaaaaagaag agctatctga atgtttagct
     8521 ggtgtcattt atcaagaact tttggaagat gccaatcacc atccttctgt tttatggagt
     8581 tatcaattta tggaggaaga atcagtaaaa aaatcatggg aggaaagtta tgaagaagct
     8641 caggaaaata tttggcagtc agaactattc taaaggatta acaagaagcc agcaaaacca
     8701 gtttgcacaa accatgggag aactgctttt atctggtttt agtctgcaag aatcccttta
     8761 tttattactc acgatccgtt cgtttccacc tgttattttg gcaaatatcc aacatcagct
     8821 aaaggaaggg caagcgttta gtgaggtact ttcgcaaata ggatatggag cagagcaact
     8881 ggtacagatc gagttagctg aacgtcatgg gaatctgccg acaactttgt tggaaattgc
     8941 caaacagttt cggcttgttg aaggatttcg caatgatttg aaaaagctgc ttgcatatcc
     9001 gatgctattg ctcacctttt tgctaggtat cttgtttagt atgcggttgt tcgttttgcc
     9061 tcagcttatt ggttcaggaa tggtcatgca agagcattgg ggtattcagc tgatacaagt
     9121 ctttcattgg tatgttctac tattcatcct agcggttact ctattggctt tactagtaag
     9181 gtatcgtctg atgaagttgt ctcctgttga tcagagtgaa tggataagca gacaattatt
     9241 gattggaccg atatattcct tgtatcaatc ggcttatttg tcactagaga ttggaaagct
     9301 ttttcatgaa ggtttcgaat taaggcaaat catagtctgc ttaaaggaaa cgaaacaaga
     9361 aagtctgatt cagcatcttg cctctaagtt gattcaagga ttggaggcag gtatgtcatt
     9421 ggctgagcag ttccagaatt atcgttttct atcagaagaa ttcagtaaaa ttgttttaca
     9481 gggagaggca aagggaagtt taggtaaaga actgattttt tacagcgaat ggacaagaaa
     9541 acagcttttc aaacgtcttc atcactggat gcattttatt cagccaatca tttttttggg
     9601 cgtagcggct ttgattttat tagtttatgc cgctgtttta ttacctgttt acggaagcat
     9661 agaggaggtt ttgccatgaa aaagagaaaa atatcttatt atagcggttt tacattgatc
     9721 gaaatgctaa tcgtcttact gatcatcagt gtattagtgt tgttgttcgt ccctaatttg
     9781 tcgcgttata ggaatcatgt agaccaagaa agtcgtgaag cgatcatcca gttggtagac
     9841 acacaaaaag agctctatgc gcttcaaaat aatggaagag ttcctactgt ggaggaattg
     9901 ttgaatgaag gctatatcaa acgagaacat gcagaaatct atcagcggcc ttgaaggtaa
     9961 ggttttagca tcaggatata cgttgtttga atcactctta ctgattttat tacttacaac
    10021 gatcctttct tttccagttc tcgcattttc tgcatggaag aatgaattgg cagtctatca
    10081 atttttcggc caatttgaaa aacgaatcta ttctacgcaa aaaatcgcta ttgtgaatca
    10141 gatccaaaca ggcttttatt ggaatagtga agagaatcaa atcatttttc atgttccgaa
    10201 tccagataaa ataaattggg aagtattaga tattcctgat gagattacct tgaaacgcca
    10261 tgcttctatt acttttgctg ctagaaccgg gaatgaaagt tcactaaaag cttatcaatt
    10321 ttattgggaa gaaaaagagc ggacgattac gtatcaattc cagataggga gtggtcgcta
    10381 tacaaaaaga attgaataaa acaggatttg ttttgttgga gtcccttaca gcgcttatga
    10441 tcgcttctgt ctgtgtctac ttagtgagct ttggccagct gtttttgctt caggcagaaa
    10501 agaaaagtgg ggaggaactg ctatttattc gaatgattta tgaagatatc aagacgcagc
    10561 ggatgtatca caaaagacca gagcgaaggg aagaaatgat cccatacgat atccaaattg
    10621 tcgataataa tggagtaatc gaaaaagtgt ttgtcaatat ggagaaagaa gcgatcagta
    10681 ttgaaaaaac aagtaattcc agcatttacg ctgattgaat gtctaattgg actgatgata
    10741 ttgagcagtc tattgctcac attcaatctt ttgattcagc aaaccatcca agtaagtgaa
    10801 tttttgcagc gtaaagatca aaaagagtgg ctaatatttt tagcacaatt agaagaagaa
    10861 ctcaagagca gtcacaatgt ctctgtgaaa aatcagcaac tgcactacac gatcgaggat
    10921 aaacagtata tcatcgaaag atatcaggca atgatacgta aaagaagaac ttccggcgga
    10981 catcaaccta tgttaacaag tatcactgag cttcaattat tggaaaaaga acacacaatt
    11041 tctttttatg tacactttga aaatggagaa gatggatatg ccatatggac aaaaaacgat
    11101 cagtagaaaa tgttataagg gctctatttt attttctgtc ttgcttttat ttcttttatg
    11161 tacgttttta ttgatggcag cattagaaag ctaccgtttg tcaatggatc ttaatatacg
    11221 aatcaaaaat tattatatag caaaaataat gaagcagatg gctttatcgg aacagtctac
    11281 gcttgccgaa agttcggaag gagtttttta ctacacaact ggatctgtaa catatcagtg
    11341 ggtacaacag tccctattct tagaggtgga agtctcaccg tttatctttc ggttcacaga
    11401 agaagtaaaa aatgatacag atactagtac agaatgatgg aatgttcgtg aaaacgccct
    11461 cttttctgtt ataacactgt ttttaataaa aaaatgtttg ccgtttcaca aataaaaaac
    11521 agtgaaaacg attgaaattt tgtcaattgt tcgatagaat taaacaggtg aaaaaattgt
    11581 tataatatat ctagaaatga ggtgcaccat gttaccagaa aaaatggaac aagggtttaa
    11641 tcaaaacctg gaagctattc agcttttaca gaatgcattg ggaacttcct ttttagaagc
    11701 ctatgtcgaa aatgcagaaa atttaataga tgattatcaa gtacgtgtgg tggatggagt
    11761 gccgacaaaa gagacaacgc aacggatcac agctctttat gaagagttga agaaactttc
    11821 tttcgagcca gaagaatggc gcagactgtc tcaattactt ttattgaagg gcagccagac
    11881 agaacatttg caggcgaacc atcaactcac tcctgatagt atcggttttt tatttgtttt
    11941 tcttattgaa caactataca caaataaaaa agcaccggtt aagattctgg atattgcggc
    12001 aggaatgggc aacttgttat taacagttct tttaaaccta tcgaatgcgg ggtaccaaac
    12061 agaaggaatt ggtgtggata ttgatgatac attgttggct gtcgcagctt ctacaagtga
    12121 tttgacacaa gcaaatgttc aatactttca tcaagacggg ttgcaggaat tattaataga
    12181 tcctgtcgat tttgcaatca gcgatttgcc aatcggttat tatccgaatg acgaaaaagc
    12241 aaaagagttt ttaacaagta ccgaagaagg ccatagttat gcacatcatt tattgctaga
    12301 gcaatcaatg aaatatgtga agccggatgg ttttggtttg tttttgatgc cgagtggatt
    12361 tttagaaacg gatcaaagtg aagaaatcaa aaaatggttt aaagaagaag gttatcttca
    12421 aggaatgatt caattgccag atgaattgtt ccgtaataaa caatcgcaaa aaagtatttt
    12481 gatcttacag aaaaaaggac cacaagcaca acaagtaaaa gaagtcttgc ttgtgaaact
    12541 tgcttcatta aaagaaccag agaaggtgac ggaatttttc aacgagttta aaaactggaa
    12601 atcatctgct ctgtaatcat tcaacgagaa ggagagtcat atgtctaaaa caattgcaat
    12661 caatgctggg agttcaagtt tgaaatggca attatatcaa atgccagaag aaaccgtagt
    12721 tgcgaaaggg atcgtcgaac gtatcggttt acaagattct atttttacca tcaagtacgg
    12781 cgataatcaa aaattcgaac aaatcatgga tatcgaaaac cacgaagtag cagtaaaaat
    12841 gctgttagat cagttgattg aactgcaaat tttaagctct tatgatgaaa tcaccggagt
    12901 agggcaccgt gttgttcacg gaggagaaac ttatggggat tcagtagtga tcgatgagaa
    12961 agtaatggac cgcattgctg aattagcaga atttgctcct ttgcataatc ctgcaaactt
    13021 aatggggatc aaagcgttta aaaagatttt acctgacatt ttgagtgtgg ctgtattcga
    13081 tacatctttc cactcaacaa tgccaaagca aaattattta tatagcttac cggtgtctta
    13141 ttatgaagat ttcaaagtaa gaaaatatgg cttccatggc acaagtcatc gttatgtgtc
    13201 ggaacgtgcg gcaaaattat tgaacaaacc gatcgaagaa ctaaaaatca tcacttgcca
    13261 cttaggaaat ggtgtatcga tcacagcagt cgatggaggt aaatccatgg atacttctat
    13321 gggattcaca ccattagctg gggtgacaat gggtacacgt tcaggtgata tcgatccagc
    13381 tgttctccca tatttaatgg aaaaattaga gattgatatt gatgaaatga tcaatgtttt
    13441 gaacaagaaa tctggtctgc taggcctaac aggattgtct agtgatatgc gtgatcttga
    13501 aaagaactat gaaaaagaac atattcgttt agcttatgac attttcgtgg accgcatccg
    13561 aaaatacatc ggcggttatg tgacaacgat gaatggtgtt gatgcaattg tctttactgc
    13621 tggtatcggc gagaatgacg gacatgtacg tagtgaaatc atcaaaggta tgtcttggtt
    13681 tggttgtgaa atcgatccag cgttgaatga attgcgtggt gaagaagtag atatctctac
    13741 aaaagaatca aaagtaagag tattagtgat cccaacagat gaggaactaa tgattgcccg
    13801 tgatgtggag cgtctgcgcg gctaagccaa agcattcgtt aggataaaag atgaaacgca
    13861 tgcaagaggg aattcttgca tgtgtttttt ttgcggagaa gaccgcaaaa tggtaattta
    13921 acttcaattt cccttctttt ttacaggatc ttcttaggga attttgcttg gaaaagtggt
    13981 caaaagggaa aagactggca ttttatttat tgattttcag gaaaatccca atattttatt
    14041 ttcattcatc tttataaggg acattacata tgtaaaaaga aaaaacattt ttagatcagc
    14101 ctcgtgggct gtcgacttta ttcttcgctt tatgtttagc tagaaaaccg atccgaaaca
    14161 ttcattgatc gaataataaa aacttgattt tccacctgta ctttgcctga atcgtgaaag
    14221 cacaggtatg aaaatcaagt tttttgttgc gaaaaaacgt cctagtcaat cagttggccg
    14281 agcggctggc ggctgatctg ctcctgatca ataacgagtg cttcttggaa gtgttgctgc
    14341 aaaaagtagc ggtcatggct gactgctagg agcgttcctt gatagtcttg cagcatttct
    14401 tcaatttctt ctcgagcata gctgtcgagg tgattggttg gttcatccaa aatcaggacg
    14461 ttgatttttt ctaaaaagag tttcagcaac gccaaacgga ttttttcacc accggataaa
    14521 tctttgatcc gtttacccac atcgctttga taaaagccac ttttggctaa ttgccgtcga
    14581 gcgacttctt cgtttccagt caatgtgatg gcgtaagcca gcaaacggct atcgggatcg
    14641 gcaaactgca gctgctgcgg caaataaccg atttgcaagc tactacctaa tttgatggtg
    14701 ccaccgtaag gcttttcctc accgagtaat aatttgagta aggttgattt tcctgcacca
    14761 ttgtcgccga tgatggctaa atgatctcca cgatagactg caaaactgct gtctttgaat
    14821 agtacttgat cagcgtactg ctggtgcaag ttttgaatga tgaaaacttc tttgccagat
    14881 tttccaccat tagacaagct ttgcagccga tttttcgggg gaggtggcgg tttgacgagt
    14941 gtcagtttcg ccaggcggcg ttccagttct ttggcttttt tgaagaagga ctcattgtct
    15001 ccttcatgtg cccactgacg aaaacgacga atcatgactt tcaaccgctg gacttctttt
    15061 tgctgcagtt cgtaattttt tgtcagctca gccaagcgag cttctttcaa gactcgaaaa
    15121 cggctgtagt ttccgggata ctcaatcaat gcaccttctt ccagttccca tgtttttgtg
    15181 gtgacttgat cgagaaattg ccgatcatga gaaacgacca gaaccgattt ttttgtattc
    15241 tgtaaatagt tttccaacca gcgaatactg ttaagatcta aatgattggt cggttcatcg
    15301 agtaaaagta aatcggcatc ggctgctaaa attttggcta aagcgacttt aactcgttcg
    15361 cctccgctaa gttctgttaa ccgtgcttcc tgacggtgtg gaatccctaa gccttgcaag
    15421 atcgctgcaa tccggtcttc taatacgtaa ccgcctagtt cttcaaagcg atgctgcagc
    15481 tcaccgtaac gggccagaca cttctctaag tttgtatctg gttctgtcat caatgcttcg
    15541 tagcgactca tttgctgttt gaggtcctgt atctcagcgg cagaatggag caagtagtgg
    15601 ttgacggtcg cttcggaaac tgtaagttct tgttcgaccg tcccgatctt taagcctttt
    15661 ttgcgactga taacaccgct gtcgacacct tctctgccgg tcaagatttg taaaaaggtt
    15721 gatttgccag ttccgttgat accgactaag gcaatttttt caccagcttc aatttgacag
    15781 gataaatcct caaataatgg attcccgccg attgtttttt taatagaaat tgcttgtatg
    15841 atcatgatct ctctccttga gaccactcaa aaaggccatg gttatccatg gcctgtgtta
    15901 tttaaactca gattatcatg agaaaaatac cttgagatgg ccattgattt tacgtgaatt
    15961 caactgtttt ggacaaactt gtcccgtcaa cagcaactgt aaaaccaatt gcatggctaa
    16021 atgcgatatg gtatcgttgg taattttcat tacttgttat tttagtcatg cgcatcatag
    16081 tattttccct ccttcgtgta gttgtctttt ccagtgtacc tgaaagtgtc agaaagttca
    16141 actagcgctg acatttactt aatatttatc gatgtgtaat tctgtcagag agcttttttt
    16201 atctgactga gggtaatgtc tcgtggacca catcattgta ttctgagcta aaccagcgtt
    16261 caggcgaaat catatggtgt ttgataaaaa actttgtcta catgacttcc ttttgccatt
    16321 tgcttaatac cgttgcatta aacagctctt ctctttggaa atctcaccaa catcgcgttc
    16381 aggagtatcg ttgtggttgc aatggcaagc ggtagccttt catcaattct tgaatgattt
    16441 accgaatgta gcacttgcct tctcgcggta cccgaacccg aaataaaatt ttagtttggc
    16501 gataaaatcg gtatccgcca tcgatacttc atattttttc gtatcagatt catcggaaac
    16561 ttccacattg acgaaccaat aagctttggc atgcttaggt cgttttaaac cacaccaggg
    16621 cgactaatcg ccctggtgtt cacttttttt tattttactt gaactcattg actgttttcc
    16681 ctttatttta aacattataa agaccgatga gtgcttgccg cgtcttttgt ttttatcacg
    16741 gttttttgtg caaaaaaacc tgccgatagt tggcaggtcg tctacgtgtt aagctttggt
    16801 gtggtcttta gctggcaatt ggttttctaa atcagttcgg acaacaagca catcgcaagc
    16861 tgcgtttcta ataacatatt cagaaacaga accaataaat aaacgttcta cagcattcaa
    16921 tcctgtggct cctaacataa tcaaatctac ttgattatct tctgggattt ctctggcaat
    16981 aatttgtttt ggtgagccat attctacgac agaggttaca ttattcaagc cagctttctt
    17041 cgcattgctt tcataatctg ccaatgtttg ctttgccatt tcagtagctt gttctgcaag
    17101 cattccatca aaggatgaaa cggtttggaa agaacgtgtg tcaatgacat gtgctaatag
    17161 aagttctccg ttatttcgga tagctacatt gaccgccttt ttaaaagcta attcagcttc
    17221 atcagaacca tctacggcaa ccatgatttt tttgtattgt tgtaacataa gcattcactc
    17281 ctcaagtcaa tcgtattgta ctcttttatt gtagaacact ttagggaaaa agagaattat
    17341 ttactgcttt ggttcagcaa ttttttttgc aaatcggata ctgaaggtgg cagaaacaat
    17401 aattacgatc agtaaaaaga ccaaggcaat aaagcgttga ttgaaaaaag ctgttaaaat
    17461 acccattacg cctaaaacag catatgcagc tccgtaaaat tgtaggaatc cttgattttt
    17521 atcatttttg ttgatcaata caaaaaagat atcctgttta ttaaataaat aatagctaac
    17581 gaataataat actaaagtgg cgataatcat taaaatccta atcatgaaca aatcctccaa
    17641 aataagcaac aaatagaaaa agcaatttgc caagagcaaa ttgctttatt ctttaaaaga
    17701 tggtaatctc cgttaatgcc gttgtttgtc ctgtagtatt gatcccgcga attcaagcag
    17761 gtgggtccca tggtcgtagc ttcgaactac caaatgataa ggcatgttac cagcagtgac
    17821 acaagacggg tcccaagata tcaataaaaa tgttcggtca acacacaaag aggacaattc
    17881 gaacatcaca gatttcccac ctctatagta gcatatgaat ttaaaaagag caatgagaga
    17941 gctcgcagaa acagaaccgt tttcttgtct agttttttgg aggatgcttt ttccactctt
    18001 ttatacggta atactgttga cccagagcct gttcatattt ccctgtatct tttggctgat
    18061 aatactgagc attcttcagt ttatctggta aatattgctg attgacccaa gcctgatcaa
    18121 aatgatgagg atactgataa cccacgccac ggttgagtga tttcgcacct ttgtaatggc
    18181 tatctctcaa atgatcagga acatctccag ctttgccctc tcgaatatca gcaagtgctg
    18241 catctaatgc catgtaggca gaattggatt ttggcgacaa gcaaagatcg acgacgacgt
    18301 ctgctagtgg gatacgtgcc tcaggcaatc ccaatttttc agcagctaat acagcgttca
    18361 ctgtacgagc cgcagcagca ggattaccta aacctatatc ttcataaccg ataaccatca
    18421 gacgccggca aatacttgcc agatcacctg cctcaactaa acgggcgaga taatgaagtg
    18481 cagcatccac atcacttcca cgaatcgatt tttgaaaagc cgaaataacg tcataatgag
    18541 catctccatt tttgtcatgg gtaagagctt ttctttggac acattcttca atgatcgaca
    18601 gtgtaagatg aatccttcct tctttatctg aaggagtcga tagtgtagcc agttccagcc
    18661 cattcaatgc actccgcaaa tcgccgttcg ttgcacgcga aaggtgaaga agagcatctt
    18721 cgtctaactg gattgcttgt tgtccaaggc cgcgttcttt atcccttaaa gcatgttcga
    18781 ctgccaactg gatgtcttgt tctgttaatg gtttgacttc aaagatctgt gtacggctgc
    18841 ggatcgctgg attgatggta atataaggat tctcagtagt cgctccgatc aagatgattc
    18901 ggccactttc taaatgagga agcagaaaat cctgttttgt tttatctaat cggtgtactt
    18961 catccaataa gaggatcact gtaccactca tttttgcttc ttccgctaca acttgtagat
    19021 ccttttttga atctgtagcg gcgtttagca tgcgaaatgc ataattagta gagccggcga
    19081 tcgcacttgc gatactcgtt tttccagtac caggaggtcc atatagaatc atggaagaga
    19141 gcatgcgagc atcgaccatg cggcgtatga tttttccttc cccgactaga tgctgctgac
    19201 caacgacttc atcgatcgtt cgaggtctca tgcgataagc caatggctgt tgcataggat
    19261 tttcctcctt cttgttttta cgtcccttaa ttatatcata tttagcaaga tgcctagaaa
    19321 gaacagcctt ctgttgtttt gttttcatag cttatccaac taatattgtg tatgataaag
    19381 taggtgagaa aaatgacgga taaacaaaag atagatgaat ttttttggaa taaaacgacg
    19441 ccagaagtgg cacgggattt attggggatg tatttggagc atgacacacc agaaggaaga
    19501 ttagctggat atattgtaga cgcggaagca tacctaggtc cagaagacga ggccgcccat
    19561 agctatggtt taagaagaac accgcgtgtg cgggcaatgt atgaaaaacc aggtacgatc
    19621 tacctttaca cgatgcatac tcatcggatt ttgaacatca ttactcagcc agaagggatt
    19681 cctcaaggag taatgatacg tgcaatcgaa cccgccgcaa tgattgatca aatgagtaaa
    19741 aatcgtggcg gaaaaactgg tccagatatc agcaacggtc cgggaaaatt agtggaagca
    19801 ttagcaattc ctcaagaact ttatggtcag tctatagcag atagttcgtt acgcttagtt
    19861 tttgagaaaa aaaagacacc aaaaaagatc aatgctttgc ctagaatcgg tatcccaaac
    19921 aaaggtgtat ggacagaaaa gccgttgcgt tttgttgtgt cgggaaatcc ttatatctct
    19981 ttacaaagaa aaaaccaaat cgagaaagat tggggttgga ggaaagaaaa tgaaaaagaa
    20041 ggatctatta acatatttag atgaaataat tgaaaaacaa gtgacagact atgatgtagc
    20101 tttagattgg gatacaaaaa atcatacgat cgagatcgtt gttcgcttgt ttgcagaaaa
    20161 taaagcacaa tttgagattg atgatgcaga agggatcgtt tcgcaagaac caattatcga
    20221 atttgaagac ggcgtacttc tttttaatcc tcagaaatct gtttttgatg aacgcaatta
    20281 tctagcagta atcccttatg aaggaaaaaa agggttggca aaatcagtag ctgattcttt
    20341 agtggaatat ctaaatgaag tattagctca agggcaaagc gatttgcttg attttttgga
    20401 tgaagacgat gacgaagctg tattcgagct tcactgggat aatcagcaac tagcagaatt
    20461 agtagaagta aaacagcaaa atgaagcaga tacttattta ccgtacccaa gttattaagg
    20521 agtgacagat atgaaatgga atgaagtaaa agtagaaact gaaagtgaag cagtcgaagc
    20581 agttgctaat attttgatgg aggcaggggc gagtggtgtc gcgattgaag attctttaga
    20641 tgttgaacat tttcagtcgg atcaatatgg tgagatttta gataaaaatg attttacatc
    20701 gctgaaagaa ggcgcactag tcatggctta ttttccggaa acgactttct taccggaaat
    20761 cttgcctttt atcaaagatc gtatcacaca attacctgag tttggtctag ctattggaaa
    20821 aaataaagta acagttagtg aagtagagga aagcaactgg gcaacagcct ggaagaaata
    20881 ctatcatccg gtgcgtatta cgcgaatgct gacggttgcg ccaagctggg aaaactacca
    20941 gacagaagat cctctagaaa aaattatcac actagatcct ggtatggcat ttggcacagg
    21001 cactcatccc acgacttcct tgacattgac agcactagaa acagtcttgc gtggtggtga
    21061 aacattgcta gatgtgggaa ctgggtcggg cgtgctaagt attgcagcaa aatatcttgg
    21121 tgcaaaagat gtctatgcct ttgatttaga cgaagtagcc gttcgttcgg cgaaagaaaa
    21181 tatggatatg aatgaaatag ccaaagatgt ccatgtatca gctaacgatc ttttgacagg
    21241 aatcgagatt gaaagtgatg taatcgttgc gaacatttta gcagatatca tcttattgat
    21301 gatcccagat gcttggcgtt tactgaagca aacaggcacg ctgatcgttt caggaatcat
    21361 tgaagagaag aagcaaatgg ttctggatgc catgttagaa caagggttta tcgtggatca
    21421 aattttccag caaaaagact ggtatgcaat tattttgaaa aaaccagagg tggaatagat
    21481 gcagcggtat tttttaaaag aatcatatga atcaaaagac tattttgttt tagaagggga
    21541 aaactatcac cacattgtac gggttatgag gatggaaccc gaggatgaag tttttttggc
    21601 attcaatgat caaatagcca ttgttgcaga aatcacggag attactgaag aggctgttta
    21661 tctgaaagaa attaaaaaag aagaaaatca aaaggaactg ccaagttcga ttaccatagc
    21721 gagtggctat cctaaagggg aaaagctgga ttggatcgtt cagaaatcca ctgaattagg
    21781 agcgcaagct tttcttggtt tcccggcatc agcctctgtc gttaaatggg atgcaaaaaa
    21841 acgtatgaaa cgacaacaac ggcttgaaaa gattgctcaa gaggcagcgg aacaatccca
    21901 tcggcagatc gtgccatcag tagagttatt ggaaacgaaa caagatttat ttgagcggct
    21961 agatgattat gacgtggtct tggttgctta tgaggaatca gcaaagcaag gcgaaaaatc
    22021 aaatgcagcc aaaattctta gtgaaacaaa accagatagt cgaatcttag ctgtctttgg
    22081 accagaaggt ggattatccc gcgatgaagt cgattatttt gtagaacaca aagggatact
    22141 ttgtggatta ggaccaagaa tccttcgtac agaaacagca cctctttatt tattaagtgc
    22201 tgctagctat caatgggaat taatgaatcc ttctttcagc taacgttctt cattaataaa
    22261 agagtatcga cagaaagaat tgaaaaaata gtcaacaatt tgtataatag aaacaattat
    22321 ttatacaatg gatacgaaaa atcgtttgaa aaagctttta aaaagcgaac atttccgtaa
    22381 aaaaacgtat aactgcacgg attttgggac aattatcaaa cagatatttg tcccgattcc
    22441 cgttttaccg aaaaaagaaa gggggatcga ttcctgtgac aaaagaagaa attttaacgg
    22501 gacccggtgt cataaagctc gttagtcaat acatgggtcc cgaacatgta gcatttgttg
    22561 agaaagcatg cgaatacgcg actgctgcac atgacggaca gtttagaaaa tcaggcgaac
    22621 cctacattat tcatcctatc caagtcgcag gtatattagc agatttaaaa atggatcccc
    22681 atacagtggc tacaggcttc ttacatgatg ttgttgaaga tacagaaatc actttagaag
    22741 atctgagaga agaatttggc gatgacgttg ctatgttagt ggacggcgta accaaattag
    22801 ggaaaataaa atataaatcc cacgaagagc agctagcaga aaaccaccga aagatgctgc
    22861 tagcaatggc tcaagattta cgagttatca tggtcaaatt agctgataga ctacataaca
    22921 tgcgtacgtt gaagcacctg cgagaagata agcaaagaag gatcgctcag gaaactttag
    22981 aaatctatgc gcctcttgca catcgtctag ggatcagccg gatcaaatgg gaattagaag
    23041 atacagcact tcgttatcta aatccaaaac agtattaccg tatcgtccac ttgatgcaga
    23101 cgaagagaga agaacgtgaa aaatacgtaa gtggtactgt tgaagatatt cgaatagcga
    23161 cagaagagct ggggattttt gcagaaatct atggacggcc aaaacacatt tattcaatct
    23221 atcgtaaaat gaaagatcag aaaaagcagt tcaacgaaat ttatgacttg ctagctattc
    23281 gagtgatcgt agattcaatc aaggattgtt atgctgtatt aggagcaatc cacacaaaat
    23341 ggaaaccaat gcccggcaga tttaaggatt atattgccat gccaaaagct aatatgtacc
    23401 aatctttgca tactaccgtg atcggtccgg caggaaatcc ggtagaaatt caaatccgaa
    23461 cacaggaaat gcatgaaatc gctgaattcg gggttgctgc acactgggcc tataaagaag
    23521 gaaaaaatga aaaagtagaa ccagatggta tgacgaaaca attaagctgg ttccatgaga
    23581 tactcgaact tcaagacgaa agctatgatg cttctgaatt tatggaaggc gtaaaaggag
    23641 atatctttag tgataaagtc tacgtcttca caccaaaagg agacgttact gagttaccaa
    23701 aaggatccgg accattggac tttgcataca gtatccatac agatatcggt aacaaaacca
    23761 ctggtgcaaa agtaaatggc aaaatggtgc agcttgatta caaattgaaa aacggagata
    23821 tcattgagat catgacttct ccaaattcat ttggcccaag tcgcgactgg ttgaaattag
    23881 ttgctactag caaagcaaga aataagatca aacgtttctt caaagcccaa gatcgagaag
    23941 aaaatgtgat caaaggccac gaatccgtgg tcaaatgtat tacagatcta ggatttacgc
    24001 ctaaagatat tttgacgaag aacaaactgc aagaagcact cgatcgtttt aattatcaaa
    24061 cagaagatga tctctatgca gctgtagggt atggagaagt tagccccttg acgatggcca
    24121 atcgtctgac tgaaaaagaa cgtaaagaac aaaaaatcga gcagcaaaag caagaagcag
    24181 aagaaatcat gaatcagccg aaaaaagaac ctgacaaaat gaaagtacgt catgaaggtg
    24241 gcgttgtcat tcaaggggta gaaaacttac taattcgtat cagtcgctgc tgtaatccga
    24301 ttcctggtga tgatatcgtt ggttatatca ctaaaggcag agggatatcc attcatcgtc
    24361 gagattgtcc gaatgttcag cctgacaaac caaatgtagc agaacgtttg attgaagtcg
    24421 aatgggaaga tacatcgaat acacgaaaag agtatgatgc agatttggaa atttacggct
    24481 ataatcgttc aggcttattg aatgatgtac ttcaaacagt caatgcgcta acgaaaaatc
    24541 tcaacagcgt tgaagcacgg acgaataaag ataaaatggc gacgatccat ttgacggttg
    24601 gtatccagaa tttatcccac ctaaagagta tcgtggataa aatcaaagca gtacctgatg
    24661 tctacagtgt acgccggacg aatggatagg aggacagata tgagagcagt tgttcaacgg
    24721 gtaagtaaag ctgctgtgtc agtcgatcag caagaaattg gaaaaattgg ctacggccta
    24781 cttgttttat taggcattca tgaaaccgat acgcaaaaag atgtggacta tctggtaaaa
    24841 aaaattgcac aaatgcgtat ttttgaagat gaacaaggaa aaatgaatat tagtgtagaa
    24901 gatgtgggag gacaaatttt aagtatctct caattcacac tgtttgcgga tacgaaaaaa
    24961 ggaaatcgac caagctttgt ggaagccgca cgaccagaaa cagctattcc tttatacgaa
    25021 tcattcaatg aaggaatcag aagtcgcggc atcacagtcg ctaccggaca attcggagca
    25081 gatatgtcgg tttctctcgt caatgatgga cctgtaacga tcattattga ttctaaaaac
    25141 aaataaagta atctggtttt cactagtaaa aactatgaaa cacgtcgctt aagttagact
    25201 gataaactct aacttaagtg gcttttttgt ctgcaaaaag cgcttctttt gtcagcagtc
    25261 ggaaaaaaag ttaagcttaa attatacaag ttatttttta taggaggttg ctgaagatga
    25321 aagaagtacc agtagtagat atcaaaatca cagatttaaa aaaattgtat caaaaaggat
    25381 acaacatgtt ggaggagtta cgccatgaag cggacgctcc cgtcgtcaaa gcaaagattt
    25441 tcaataaaga agctatcacg atctacggat catcagcagc aaaagtattt tatgatccaa
    25501 ggaatttcaa acgaaaaggt gctatgccaa aattagtatt gaagacactt tttggtcaag
    25561 gtggagtaca gactttggat ggagctgctc atcaccatcg gaaaaatatt tttatggatc
    25621 taatgacacc ggaaagaatg gaagattatc atcgtatctt agataagaat ctgacacaag
    25681 cacttgaagc acagcatggt caatttgaac tatttgattt aagtaagatg gttttcttta
    25741 catctatttg cgagtgggca ggtatcaatt tatcagcgat ttctaaagat gaggtcgaaa
    25801 aattagcaga atatcaaatc tctatgatca gcggaacgtt tacttctccg attgatcaca
    25861 taaaaggtgt cgagaatcgc aaaaaatcag aaaaatgggc gcaaggcttg attgaagaag
    25921 ctcgacaaaa tcctgtggct ggaaaagaaa atgtggcatt atatgctttt gccaatgcca
    25981 cagatttaga tggtcagctt ttacctctgg aagtggcagc tgttgaatta ttgaacatca
    26041 tccgtccaac ggttgctcta actgtgtggg cggcattgat gggacatgca cttttcagta
    26101 gaccagattt gtatcagcaa ttaaaaaatg acttttcgac gttacaagat ccgtttattc
    26161 aagaaatgag acgctattat cctttcttcc caatgctacc tgcgatttcg ctgaaagaag
    26221 tagaagtaga tggttatcgt ataccagaag gcagttgggt tattttagat ttatatggaa
    26281 cagaccatga tgaacgaaca gttgaagcgc cagattcctt tatgatcaaa cggtatgtag
    26341 ggaaagcaaa agatatttcc tataaagaag aatatgagat gattgcacaa ggcgggggaa
    26401 attttcgaca aatgcatcgc tgtgcaggag aatggatcac tcttcatagt ctacgtgtgt
    26461 tttccgatca gctagtaaat aagtttgagt tctctgtacc tgaacaagat tggacgattc
    26521 cattcaatca gtttccgact tatccgaata gccgagcgct actttacaag aattagatta
    26581 gcataaactt atcgaaaaaa aggaagatca aacagtgctg atcttccttt tttcatatta
    26641 ctataaattg ataaggtcaa ttgatcaaaa tccacgaaat gcttcatcaa tggtttgata
    26701 atcttcattg gataaatgca aatctaaagc ttggacattg tcagatactt gctctggacg
    26761 cttagctcca ggtataacta cagacactcg tggattcttc atgtaccaag ctaaaacaag
    26821 ttgcgcagga gtggcttggt atcttttagc aatggggcga agtacatcga cagcggttaa
    26881 aatttctctg aaacgttctc cttggaaatc tggatttctt tttcgaggat ctccttcacc
    26941 aaattgtttt tcctcaccaa gttcatattt tcctgtcagc aaaccggaag caagaggaaa
    27001 atagggaaca aaactgattt tgtttttttc aagataaggg aataattctt tttcagcctg
    27061 ccgatggatc aaactgtatt tatcttctac tacatcgaca tatccatctg cattcgcttc
    27121 tttcaattgt tctaacgtga agtttgacac accgactgct cggatttttc ctgcttcttt
    27181 taattcgtgc aatgtagcaa ctgattcatt ttttggtgtg ctttcatccg gaaagtggat
    27241 ataaaaaatg tcgatgtaat cagtttgcag acgttttagt gcatcttcca ccgattgttt
    27301 gagaaactca ggagaattat caaatgttcg ccctttattt ggtacatgag cagcttttgt
    27361 agcgatgacg acacgtgagc gatcatattc tttttccttc agtacctcgc caatcagttc
    27421 ttcggaacgg ccgtttccgt aagcataagc ggtatcgatc aaattgatcc cgctattcaa
    27481 agctgtacga actacttgtt ttcctgtctc atcttccaaa ccgtcaaaaa gattatgtcc
    27541 tccaacggca tttgctccta atccaagctg ttctgcgtag acttgtgaat gtccgattct
    27601 tatttctgcc atagctgatt cctccttttt gtctagtcta aaacaaaata ccaaaaagct
    27661 gaactaaaac gtttttgtga ggggaaatag tcagatatct cttgactttg agactggttt
    27721 ttagtaggtt ataagtaata tcgaatgtca atgaaagagc gagtaagttt ttgaaacttt
    27781 acaagagagg atcatcgagg ctgaaaatga tctaaagttt cattagccta aagacactct
    27841 ggagatggac gagtgaaaag ccgtcccgcg tacgagcgtt attcgtaaga ggaaagagaa
    27901 atctttcaaa attaggtggt accgtgtatg aatttcattc acccttgttc atgatgaaca
    27961 agggtgattt ttttatttac atagctaaga aagggagaga aaactatgag tttccaaaga
    28021 ccaaaaggaa caaatgatat tttgccaggc gaatcagaaa aatggcagtt tgtcgaagaa
    28081 acagcacgtt tattattcag agattatcag tataatgaaa tgcgtacacc gatttttgaa
    28141 cactatgaag tgatatcccg aagtgtaggg gatacaacgg atatcgtttc aaaagagatg
    28201 tatgattttt atgacaaagg ggaacgccat gtgacgcttc gaccagaagg tacagcacca
    28261 atcgttcgtt cttttgttga gcataaattg ttcggcccag agtatgcgaa accgttcaaa
    28321 actttttata tgggaccaat gtttcgctac gaacgccctc aaaaaggacg gttacgtcaa
    28381 ttccatcaaa tcggagtaga agcatttgga tcagaaaacc ctgcaactga tgtggagagc
    28441 atggtgatgg cacttgattt cttcaaacag ttggggatca cgcaaatccg gctagtcatc
    28501 aattcattag gtgataaaga aacgcgtcaa gcctatcgtc aagcattgat cgactatctt
    28561 ttaccttttg aatcagagct gagtgaagac tctaaacgcc gccttcatga aaatccatta
    28621 cgcgtattgg acagtaaaga caaacgagat caaaaatttg tggcagaagc tccatctatc
    28681 ttagattatc taagcgagcc tgctcaaaaa cattttgata ccgttgtttc catgctggat
    28741 gcattggctg ttccttatga aatcgacagt aatatggttc gcggactaga ttattacaca
    28801 catacgattt ttgaaatcat gagtgacgca ccaaaaatgg gggcacaagc aacgatttgc
    28861 gcaggcggac gttatgacaa tctagtggaa gaactaggtg gtccttcaac acctggcttc
    28921 ggatttgcaa tgggtatcga gcgattactc ttgactatgg aggcagagga agtagttatc
    28981 cctgcattta atgagttgga tgcttacgtg gtcgcactcg gagacgaaac aaatatcgaa
    29041 gcattgaaag tggtccaagc gattcgaaac tttggttttt cagctgaccg cgacttcatg
    29101 aaccgtaaag caaaagcgca atttaagaca gcagataaag cgaatgccaa attagtattg
    29161 gtgatcggtg aagatgagct tgctagtcaa acgattaatg tcaaagcaat ggcaagccga
    29221 aaagaaaaaa gttttccatt agaagagata tatgaacatt ttgatgaagt ctatgatgaa
    29281 atgactttat tcgagtagga ggaaaaaaat aaatggcaca aagaacgatc tattgcggat
    29341 tagtttccga acaacaatta gaacaaacag ttacattaaa aggatgggta caaaaaagac
    29401 gagaccttgg gggagtaatc tttatcgacc tacgtgatcg tgaaggaatc gttcaaatcg
    29461 tctttaatcc tgaaatcaac aaagaagcat gggaaatcgc ggataaatgt cgcagtgaat
    29521 acgtgatcga agtgactggg gaagttagaa gacgcggaga aaatgcagta aatcctaaaa
    29581 tggccactgg tgaattcgaa gtgattgcaa gtgaaatcgt gattttgaat caagcaaaaa
    29641 ccccgccatt tcaaattgaa gatgatcaag caatcagtga cgaaatacgt ttgaaatatc
    29701 gttatttgga tctgcgtcgt ccaaaaatga ctaaaaacat caaattaaga aatgcgacaa
    29761 caaaagcgat tcgtcattat ttagatgata atgactttct cgatatcgaa acaccttacc
    29821 tagggaaatc tacaccagaa ggcgcaagag actacctagt tccttcacgt gtccatgctg
    29881 gacatttcta tgcgttgccg caatctcctc aattgtttaa acaattgctg atgaatgctg
    29941 gattcgaccg ttattatcaa atcgttcgtt gtttccgcga tgaagattta cgtggagacc
    30001 gtcagcctga atttacgcaa gtagatattg aaacaacgtt cttaacagca gaagaaatcc
    30061 aaacttacac agagggattg attgcgaagg taatgaaaga agttcgcggt atcgaagtca
    30121 cattgccatt tcctcgtatg acctatgatg aagcaatggc tcgctacggc agcgacaaac
    30181 cggatacacg ttttgatatg gaattgatcg atctaagcga tacagtcaaa gaagtagaat
    30241 tcaaagtctt ccaaatggct cttgaaaacg gcggtgtcgt gaaagcattg aatgctaaag
    30301 gcgctgcaga tcgctactca cgaaaagaca tggatcagtt aggtcaatat gtaggacaat
    30361 tcggagctaa ggggcttgca tggctgaaag tagaagaaga cggattgaaa ggtccaattg
    30421 ctaaattcat gggagaagca acagaagcaa tcattaaagc aacagatgca aaaccaggtg
    30481 acttgctgat gtttggcgca gataaaagtg aaatcgtcgc tgctgcatta ggtgctatcc
    30541 ggacacgttt aggaaaagaa ttaggactaa ttgatgaatc gaaattcaat ttcttatggg
    30601 taactgattg gccacaattt gaattttcag aagaagaagg tcgatatgtc tctgctcacc
    30661 atccattcac gatgccaaaa gaagaagata tcccgttatt ggctgaagac cctgcaaaag
    30721 tctatgcaga agcttatgat atcgtcttga acggttatga attaggcgga ggttctatcc
    30781 gtattcatac tcgtgagctt caagaaaaag tactagaaac tctaggcttt acaaaagaac
    30841 aaatggaaga acaatttggt ttcttgttaa cagctttaga ttacggattc cctccacatg
    30901 gcggtattgc attaggattg gaccgttttg caatgttatt agccggagaa gataatattc
    30961 gtgaagtcat tgcctttcct aaaaacggaa aagcagcaga tgtgatgagt gatgcaccaa
    31021 gtatggtttc gcctttacaa ttgttcgaat tgaatattga tgtaacgaat atagaagaat
    31081 agccgataaa aaggtaaaaa ggatttgtcg aatacgcttc ttttgacaac cttgatttaa
    31141 ttgaaaaaca ctttataatg aagccataac atataaagcg gggcttttcc atgaaaaaaa
    31201 cattcgaaaa ttgggcttat catgattaca cgaccaagct ttcggtatct atcgtttatg
    31261 cgttgatcgc atcagtcgca ttgaatttct tttatcagcc aggacatatt tattcaagtg
    31321 gtattactgg tctagctcag attttgacga ctttgtcaaa atcactgata ggattcgaag
    31381 taccggtatc aacaactttg tatttactga atataccttt gtttgtattg gcgtggttaa
    31441 aaatcgggaa gaagtttaca attttcactt ttatcacagt cactttgacc tccctttgta
    31501 tccatatttt accggaaaca gtcctatcta ccgatccaat catctgtgcg ttgtttgggg
    31561 gggctgtgat gggactaggt attgggctag cgttgagaaa cggcctatca tcgggcggtc
    31621 tagatatcgt gagtatcacg attcgtaaaa aaacaggaaa gtcgattggt tctatttcga
    31681 tctacttcaa tgcattgatc gtttttgttg ccggaattct atttggctgg caatatatgt
    31741 tttacagtac gttgtctatt ttcgtcagtg gaaaagtaac tgatgtcgtt tatactaaac
    31801 aaaagaagat gcaggtaatg atcgtaacga aacatccaga aaaagtagta aatgaaatcc
    31861 aaaactgtat gcgtagaggg atcacgatca tcaatgaagc agaaggtgct tataagcatg
    31921 ataagcagac agtattgatg acgatcgtta cacgatacga actgcctcta cttagagaag
    31981 caatgaaagc ttctgatcca caagcttttg taagtattgc agaaaacgtc cagatacttg
    32041 gtcgtttcta tgaggatggc atttagatcg agtttgacaa aaattcatga aatactgctg
    32101 tagacagacg ttcgtttgtc tgcagttttt ttctaccata gtagaatcag caaagaaaaa
    32161 ctgctttttt atttgaaatt ttcttaaagt tgaaaaaaag catgtttatt tttttaaatt
    32221 tatgggatga tagaaaaaaa tagtagagaa aggacacgat tctacttgct attttcactt
    32281 aatacccgta tattacgaat gaaaaaagtt tatgaaaagt tggaatattg aatggaaaaa
    32341 caaaaaaggt taaaaaacag ccgctacatc actgggtttg atgggctccg ttcattagct
    32401 gtggtgggtg ttatcttcta tcaccttctg ccaactagta tgaaaggcgg ctatttgggc
    32461 gttccgattt ttttcgtcgt atctggttat ttgatcacgg atctgctgcg gcaggaatgg
    32521 gaacaaaatg gaaaaatcaa tatttggcaa ttttatgtca gaagaatgaa gagactctat
    32581 ccggcacttg tttttatgct tgtgacagct tcggcttata tcactttgtt tcagcgaggg
    32641 ctgttaaaca atcttcgagg agttgtggtc agcagcttac tgtatgtcaa caactggtgg
    32701 caaatcaata acggtttatc ttatttcgat cgatttgcta atgagtcacc gtttacgcat
    32761 atctggtctt tagcagtaga aggtcaaaac tatttggttt ggccgatctt gtttgtattg
    32821 ttgatggtat ttgttcgtaa aagaaaatgg atcttttata ctgtgttagg tacatccttc
    32881 ctctccgcca tcttgatgat gatcttgtat acaccaggag gcgatccaac ccgtgtttat
    32941 tacggtaccg acactcgtct gttttctata tggttgggaa gtgcgcttgc gtttgtttgg
    33001 ccaagtacgc gtttaaagaa aaacatcccg aaacaagcga aaaatattct gaatatcgct
    33061 ggaggaatct cgcttttggc actgattctt tgcttcttct ttttagatga tcattacaat
    33121 ttcatctatt acggaggaat gctcctagtg agtctgttat gcgtagtgct agttgcagtg
    33181 acagcacacc ccggagcaag tttgaatcga tggctgacaa atccagtatt tacttggatt
    33241 ggcaaacgaa gctatggcat ttatctgtat cagtttccag ttatgatttt ttatgaagca
    33301 aaggtgactg atattgccga tcatgttttg ttgcatactt tagtggaaat cacattgatt
    33361 ctaatcatca gtgaactttc ttatcgatat gtggagcgtc cgctagcacg ttttgattat
    33421 ggtcgtacat tccaagtgat gaaaggatgg ttcagcaaac cgatcatcag taagagcaaa
    33481 ccatgggttg ttccaggcac attacttgta gcaattgcac tcgttggttt cgttacggca
    33541 ccgaaaaacg ctgtaacagc cgatcaaaaa caactgcagg caaaaatcgc tgaaagtaaa
    33601 aaattagcag aagaaaccag aaacaattca gaaaacacca ctagttcggt tgaccaagcg
    33661 atccttgata agtacgagtt gtccaaggca caagggaata aggcacaaaa attagaacta
    33721 acggcatttg gtgattcagt tatgttggat gctgcaacgg atctacaaga actttatcca
    33781 aaagtagtgg tagatggaga tgtcggacga caattatatg ccagtgtacc gtacattgaa
    33841 aaattaaagg aacaagattt gttgaaagac actgttctga ttggactagg aacgaatggc
    33901 tcattctcgg aagctcagtt tgatagtgtg atggatgcaa tcggtgatcg aaaagtatac
    33961 tgggtcaatg tccgagtacc gacgaagcgc tggcaaaatg acgtgaatgc gatgcttgaa
    34021 cagatgacga aaaaatacga caatatgacg ctgattgatt ggtacagcta cagtaatgac
    34081 catagtgact ggttttatga tgatcaagtc catccaaatc ctgaagggat gacacattac
    34141 attcacttag tcagcgaagc cttgctagga ggaagttcaa gtacgaacag cagtgagaca
    34201 aacgtgacag aatgatagct acaaaaaact tcaggcaaaa acatttgttt ttgcctgaag
    34261 tttttttata tttaccgtgt ttttaacatt catatagatt caggaagcaa aacggttgag
    34321 tgtgtctgta aataacgttc tttttgtttt cgggtgagtt ttttgaatgc agcttctgct
    34381 tttgttgctt cgcttcttga agaaaatact tctgcatgga tcatcttaac aggtcttctt
    34441 ttttgaagac gagtatattt agcaccagta ccattgttat gttcctctaa tcgtctagaa
    34501 agatcggttg tatatccacc ataaaatgtc tgatctttac agaataatac gtaaaaataa
    34561 tgttcatttg ccatagagca tctcacgaat ctctgcagtg tattctccat ccatattgta
    34621 agtgatcaat ggtggagcga ctttgaatcc gtctaatttg ccttctttga ttccttcaac
    34681 taacaaaata tttgcctctt ttccaggttt tgggtaaaca aattggatcc ttttaggtgc
    34741 aattcgatag tcttccatga cctgaatgat ttctaagaac cgatcaggac gatggaccat
    34801 agtaaagcgt ccatttgttt ttagtagctt acttgaaata tcgatcactt cttctaacgt
    34861 cgtatgaatc tcatgacggg cgattgccag gtgtttatta gggttcgttt tatttgttgg
    34921 cagccctttg aaataaggtg gattacagac gactaagtca caagaattat gtcgaacgac
    34981 agataagctg tctttcagat cgatggtgtg gacagtcatt tgttcattta aatggttaag
    35041 cgcgatacta cgtcttgcca tgtctgctag acgaggttga agttcgatag cgtcgatagc
    35101 cgcctgggtt cgtttactta aaaaaagtcc aactgcgcca tttcctgcac aaaggtcaac
    35161 aatcttccct tttttaggta cacgggaaaa gtgagcaagc agcacagcat ctaaagaaaa
    35221 agaaaacact ttggaacttt ggataatctt gatatcttct gcgtataatt ggtcgattcg
    35281 ttcgtcttcg tgaagcatgg attccctcca aaatgaaaaa aatagtcgtc tgtattatac
    35341 tatttttatt aaaaagaacc aaggtggctt gtcaaacctc tattttttat gcatactatg
    35401 accataagaa gggaaaggaa gagactatgt tttatcgatt tatgcgcggg gtagttcgag
    35461 tactattagc cttagttaat ggaaatgccc gctatgagaa taaagaagtt ttaccgcaag
    35521 atgagaatta catactagtt gctccccatc gtacttggtg ggacccatta tatctggcgg
    35581 tagctgcagc acccaaggaa ttcagcttta tggcaaaaga agaactgttc aaaaatccag
    35641 ttctgcgatt tatattaact cgatccaatg cttttccagt taaaagagaa aatccaggac
    35701 caagcgtcat taaaacacct gtaaagattt tgaaatcgac aaatttgagt ttgatcatgt
    35761 ttcccagtgg gacaagacat gctacagaac ttaaaggcgg aatggcattg atttccagaa
    35821 tgtctaaagc gaaaatcgtg ccagctgtat atcaaggtcc gttgacactt ggggatctgt
    35881 tcaagcgtca gagagtgaca gtgcgtttcg gcgaaccaat cgacttatca gatatcaaga
    35941 aaacggataa agaaggtatg gcggagatcg aacgacgaac acaagcagct tttgacaaat
    36001 tggacaaaga agtgaaccct gatttcaaat atgaagtcaa aaaaaaataa aatgataagt
    36061 ttatgcgtgg gcggtctttt gaatctactg tcctgttcag ttcagacttt ttcaatgaaa
    36121 acgagggaga gacgtcaagt ctgccctctt tttgcgttcc aatatgtaaa atagaagaca
    36181 ggtgtcatgt aatggatcaa agtgttataa taattagaag gacatttttt gaggtgattg
    36241 aatgcgtttt ttacatacag ccgattggca tatcggaaaa aaactacaag gttatgactt
    36301 gattgaagac cagcgtcatg tactatcttc tatactagat atcgcgaaag aagaaaaagt
    36361 agaggcaatc gtgattgccg gagacttata tgataggagt gtcccagctg ttgatgccgt
    36421 agaattatac aatgaattga tggtcgattg gaatttaaag gaaaagatcc cgatttttgc
    36481 tatatcagga aatcacgata gcagtacgag actttcagcg ggtacgccat ggttcagtta
    36541 ttcgaactat tttttgcgaa cacagctagc agaagcattt gaaccagtcg agtttaaaaa
    36601 cgtacaattt ttctttcttc cttactttga accaattgca gcgagattat attttgaaga
    36661 tgacaatatc cgaacgatca agcaagcggt agccaaggtg atagataaaa tgcaggagct
    36721 atttgattca gaaaaaaaac aagtattgat tagccatttt tttgtaatgg gaagtgtaaa
    36781 atctgattcg gaaacgaaaa tcgaagtagg cgggttggat tcgatccctg gtgaactact
    36841 tacaccgttt gattatgtag cactaggaca tttgcataat caagctgctt tgagacagga
    36901 taatgctcgc tatagcggtt ccccattgaa attctcttta tctgagatca accaaaaaaa
    36961 aggcgtatgg atcgttgacc tgacaacagg cctggagttg aattttaggg agatcgaacc
    37021 cctgcatgat attgaagaaa taacagcgag tttcaaagaa ttgctggatc ctgcctttta
    37081 tcagtccgtc aatcgggaga attacatcta tatctatctc actgatagaa cgatcatccc
    37141 gaatatgatg aaccagcttc ggcaaatata tcctcgtatt ttggggattg aacgggcaaa
    37201 cggtcgagca gaacaaacaa agcgcaaacg aaaagtacta gaaatgaaag atcctcaaaa
    37261 attagcagaa gcatttttta gtgaaatgac ggaagagcag ctaactgcaa accaagaaaa
    37321 atggctcgga gaaacgttgc aagaaatcat ggaaatggaa tgatcaagaa tgaaaccgaa
    37381 aaaattacaa cttaaaaatt ttggtccttt tatcaatgag accgtagatt tttcacgttt
    37441 gacagaagca ccgctttttt tgatcagcgg gaagacagga gctggcaaaa cgacgatttt
    37501 tgatgggatc accttcgcac tttttggtga aacttccgga agacttcgct ctggaaaaga
    37561 gatgcgttct ttgtttgcta caccagacga agaaacaagc gtgacttttt cttttgaaca
    37621 tcagcagatg agctatgaaa tcgaacgaaa accagaacaa gttttagcaa aacgaaaagg
    37681 aaacggaaca aaaaaacagg cagccaaagt aacgttgacc atttttgatg ggaaaggaaa
    37741 agaaataaaa caaatcacaa aacgtacaga agcagatcag ttgatcagag aactgatgaa
    37801 tctcgatgcg aaacagtttt ctcaaatcgt tttactaccc caaggagaat tccgtaattt
    37861 tttggtttca tcaagcagtg ataaagagac tgttttacgt catttattcg gtactcaatt
    37921 tttccaacag ttcaatgagc gattaaaaga aaaagcaaaa caacagcaac aaaaattgga
    37981 tcatttagag caagagctgc atcttctgca aaaaaggttt gttttagtca aagaagagga
    38041 accagcagca gggtttgaag ccgttttagc ccaatggaca aaccatcagg caatactcga
    38101 aaaacaaatc acggaagaaa aagaagctct aacggaactt caggaaaaac aaaagcaact
    38161 agaaaattcc tactatcgtt ttgaaagctt gaaaaaaagt tatgaagaaa aaacgatatt
    38221 aataaacaag caaaaggaat tagctgctca aaaagacgaa atagaggaaa agaaacgatg
    38281 gattgggtat tatgaattta cgcaacgatt agtcgaacca atccagcgcc tacaagaaat
    38341 aaaagttgaa aaaatagaac tgtcacaaaa aagtagtgag caaacaaaga aactagcgat
    38401 gactacgcag aattatgaag agtggcaaaa aaatgaagca aaccgcgtac gccgacaaac
    38461 aaaaatcaaa gaagctgctc aaaaactgca aaacaaacag atgatggtgc caattgtcga
    38521 atccttacgt agtaaaaaac aagacgcaga acaattaaca atttcattgg ataaagaaga
    38581 attgaatgcc gagaagctgt atcaaaatct cgctatctat caggaaagaa ctcgaattct
    38641 tcaagaaaat ttactggatc aggaaaaact gcaagaagat cgtcttgctt ttggacagtt
    38701 aaaatatcta gatgaaaagc agcaagaaat agaaaaacaa aaagcaaaag acactgggtc
    38761 gctcgcacag ataagagaag aactcaaaaa agcaactgaa gaaataacaa aaaatagtca
    38821 gctattgaaa gaacagacag aacaagcaga acagctgaaa agccaatggg caaagcagca
    38881 aattgctcgt cttcagcttt ttttgcgtcc aggggagcca tgtcttgttt gtggatcaac
    38941 ggaacacccc atacaacaat taaaacacga acagccaaat aaggaagata tcttaaaagt
    39001 agaacaacaa ctggcagaag ctgagtctgc tgtagaaaga actcagcaaa tcattgccaa
    39061 aagtgaagca catgaaaata atcttcaaca acaattatca gatttagaac aaaaaatcat
    39121 ggcaacgaat atacaattgg ctgaacaaga agaacacttg caacaggctt tgaaaaaggc
    39181 atttcctgag ataacagaac aaaaaacaaa aacaactctt gtagtaatcg aacaatcttt
    39241 agatagacga aaaagcaaga tggccaatgc aagaatagag ctggaagaaa taagacaaca
    39301 agcagaaaag ctcgaacaac aattagctgt ctacaaacag cagcagacag aaaaaaataa
    39361 tcagctccag caactgcaag gagaaatcaa aagtttagaa caacaattgc aagatacgga
    39421 tagtaactgt ttagaagagg agatacgacg acttgaaaaa cagttagaag aagactcgaa
    39481 tcaactagct gttgagcaga aagcaggagt gcaattgttg caagatcttc atacgcttcg
    39541 gacacagctt gatcttcaac atgaacaaat agaaaaaata gatgaaaaaa tagaaaagga
    39601 acaagaaaga atagctaaaa agttagaaag ccagtcgtat ttttcaacaa ttgaagaaat
    39661 ctgtgcattt gcacaacagc aagcacaata taaagaaaac caacgtacag ttacttctta
    39721 tcatgaagag caattagtga cagctgaccg gctgcgtcaa ttagaaaata tccagctaac
    39781 tgagacattc ccagatacag aagagatcag ccaacagtta gaagaaataa gacgtatgat
    39841 cgaaataaag caagaaaaga tatacggttt acaagaacaa aaaattagta atcaaaaaat
    39901 ctacgatgaa tgtctttcga tttatcacac aagccagacg aaattagatg agcttacgca
    39961 attacagcag ctttcgcaaa cattcaacgg agaaaatcct aagaagacta gtttggaacg
    40021 gtatgtgctt caggtttatc ttcaagaagt gttacaagta gcaaatgatc atctccaacg
    40081 tttaacgaaa aatcgttatc aatttgagct agcggatacc attggcagtt atcgagggaa
    40141 aaccggatta gaaatcaata tctatgatga tcaggcaggt atgtctcgaa gtgcgcatac
    40201 cctgtctggc ggtgagagtt ttattgcagc actttcttta gcattagctc ttgccgatgt
    40261 gatccagaca caagctggtg gtgtagcaat cgatgcattg tttattgatg aaggatttgg
    40321 gtcattagat gaagaagctt tggaaatggc aatggaagct ttagaaacga tcgaaagtga
    40381 aggaagaatg atcggcatca ttagtcatgt aagagaattg aaagaacgag tattacaaca
    40441 aataagaatt gatacagaag gtagcggaca aagcaaaata cgctatcaac ttggataaaa
    40501 agggagattg gtaactatga aatggagtat tccagaaaaa gtcattgcac gtggacgtca
    40561 atacttgcaa gaaggccgag tgttatcggt tgtccctgac caagaagaaa acgtgtggca
    40621 tgcagaagtc ttgggcagtg aattgtatat ggttgatttg gatggtacag caaaagagat
    40681 agattactgc caatgtccct attgggagga acataaatat tgtaagcata cagttgctgt
    40741 ggaactttat ttacggtcga aaaatctatc tcgtatcatg aaaaaagacc agccaatgct
    40801 agaaccggta aaagcaacaa gtgagggaga aatcattgca aaaggttttt ctcgtctaaa
    40861 aacacaaaac aatcctcaag cggtgcaacc tttgattatt gaataccaag tagaaacgat
    40921 tgagactaat cagtatcacc cagagctttc tattttggca ctttacttgc gtatcggttc
    40981 attggcatca ccgaaaaaaa catatatcgt aaaaaacatc tatgattttt tacaagctta
    41041 cacagaaaaa gaaacttaca ctgttaataa acagtaccag tttcgtctag ataaacgggc
    41101 gtttcaaaaa gaagatcaaa aaatactcac gcatcttgca ggaagtgctc agacgcatca
    41161 attattaggt acgaacggct tacaagtcaa aggaaaacta gataaaagat atctgcttct
    41221 cccagtagaa caagcccgct tcctgttaga gcagatgaat cagactacac gtttgcatct
    41281 gcagataaat gaacaaaacg atcaaggaat acaattttcc gatcaaaaca aacctttatc
    41341 attcaaagtg gaaaaatttg gagaagatta tttgctgcaa gcattgaatg attttgattt
    41401 tttctttatg cattatcagt ggggagttat ccaagggaca ttttattctc tgacgaaata
    41461 tcaacaaacg gtttatcaaa cttggaaaca attgattcgc cgattggaga aaccagaagt
    41521 agtgttcaag aaaaaagaat taccgtcttt gtttaaagag attatccctc tgctgtcaga
    41581 gatcggcgac gtagctattg cccctgcagt agaagaggaa gtagcagata tccccgtcga
    41641 atttattttc tttttccgaa aagcaaaagg aaaaatccaa gctcgagtcg atttcgtcta
    41701 tggtgaagtc atctattcga ctgacccgaa gcatgaggtc tcgacagaac aggcttttca
    41761 ggtgttacgt gacacagtag aagagaaacg agtacttgat ctattcagaa tgtatcgcta
    41821 ccagaaaaat gaaactggtt atgaacgtcc attgccaagc ggggaagaac tatatgcctt
    41881 tttccgcaca gaactatctg tcttccgtca gtttggtgaa gtcagacttg gaagaaaatt
    41941 gcgagagttg tatttagatg cgcataaaca tcaaccgaaa atcgaagtaa ccgagaccgg
    42001 ttcatggctc gatattcgat tcgatgtgac agggatagag gagcaagaaa tcgatcatgt
    42061 cctgcaaagc ttgctgagaa atgatgcttt ttatacatta gaaaatggtc aggttctttc
    42121 ttttgattca gaagaatttc aacaaacaag ccaagtgttg caacaattac gggaatcgat
    42181 acgtacagaa gaaggaacga tccatgtacc taaaaatcaa ggattgatca ttcaaaatca
    42241 attggaaaaa agcaatgcta cttttagtga atcgttccaa acgatggtac aagatctcat
    42301 tcatccagaa agataccagg cacagcttcc caaaggattg aatgcaacga tgagagatta
    42361 tcaaaagcaa ggttttcgat ggttgaagat gttaggtcat tatcagtttg gcggtatttt
    42421 agccgatgaa atgggacttg ggaaaacact acagacaatt gcctttttac tttcggaaaa
    42481 agaagaacgg aaaagcttct ctgctttgat cgtagcgcct gcgagcttaa tttacaactg
    42541 gcaggcagag gtgagaaaat tcgccccttc tttaagtatc caagtaatca atgggaataa
    42601 aaaagaacgt gaagaattac tggctaaaga cacagatatc cgagtgactt cttatgccag
    42661 cttaagacag gatctagcta attatcagtc gcaaaaaatt gattatttga ttcttgatga
    42721 ggcacaaatg gtcaaaaata gcagtacgaa aactgcacaa gcattgagag aattagctgt
    42781 acctcagcgg tttgcactga gtgggacacc aatcgagaat aatttagaag aattgtggtc
    42841 attgtttgca acgattatgc caggattttt cccgactaaa acaaaattca gggaacttgc
    42901 cgcagaagaa attgcgcaaa tgattcgacc gtttatttta cggcgagata aacaaactgt
    42961 gttgaaagac ttgccggaaa aaacagagat gaatctatat tctgcactta cagaagaaca
    43021 aaaaactgtt tatttagctt acttgcgtca aatgcgtgaa gaaatcacat caatggattc
    43081 tgaagcattc aagaaaaacc ggatcgggat acttgctggt ctgacaagac tgcgacaaat
    43141 ttgctgcgat cctcgtctgt ttattgaaga ttaccaaggc ggttccggca agctcgaaca
    43201 agtaaaagat ctactggtag ctgccaaaga gaacaaacga agagttttgc tgttttctca
    43261 atttacaggg atgctgacta tcttgcaaga agagttagcc gagctaggga tctcgacatt
    43321 ttatttaaga ggcagtacga aaccacaaga tcggttaagt atggtagacg catttaatgc
    43381 tggcgaaaaa gatgtttttc tgatttcctt aaaggctggg ggaactggat tgaatctcac
    43441 gggagcagat acggtcatct tgtatgacct ttggtggaat cctgccattg aagaacaagc
    43501 tgctggacgt gcacatcgga tcggacaaaa aaatgtggta gaagtgtggc gtatgatctc
    43561 tgaaggaacg attgaggaac gcatggattc actccagcaa gaaaaacgcg aactgttcca
    43621 aaaagtgatc caaggtaatg aagaacagtt gacgaaactg actgaagaag acatccgcat
    43681 gattttaagt gtaggagaaa tcgaggagta agagactcga aaaagcgttc agtaatgggt
    43741 aagaaagcct ttctaaagaa gcgattgttt atttgattta aaaaatagca aggaggctgg
    43801 gattccattt tatcccagct tccttgctat cattttttta tttctatttt taaaggttat
    43861 acaaagattg tcttcattgt ctctaacagc tgatcaaaag aagaaatctc gatatcgcaa
    43921 attggagtct gttcaatttt gcgttctcga tggttgaacc aaagcgcttg ccagttagca
    43981 ctttttgcac ctagaacatc attgtcgtaa ttatcgccaa cgtataaggt ctcttctgga
    44041 agcatatgaa attctttctc agccagctga aaaatctctt tttctggttt ttggaaacct
    44101 gttgcttgag aaatgagcat attgcgggaa ggaatccaat tgttcaattg aagttgcttc
    44161 agtttttttg tctgatggtc agtcggccca tttgtgataa ttcctaatgg gacattcttt
    44221 tccttcaaga aatcgagggt ttttttgacc tcctcatgca agcagatatt atcaagttct
    44281 tcctcgtaaa ttttttgaaa taagaggcca tcttcttccg taatatgagg gtagtctaaa
    44341 tcttttagtg attggctgat ccgatgtgct cgcatatatt ctagtgtcca atctcctgcc
    44401 attacttttg ggaagttttc atcactatga tggcggaacc ggatatatag tggatgcata
    44461 tctgcatctg aaacaagcgg aacgactctt ttgaccgcgt ttcgaaatgg ctgctgctga
    44521 tcatacatcg tatcatcaac atcaaacaca actgatttaa tcaaaatttt acacgccttt
    44581 cggttttcat tgattttttc acaaatcctt gactattgta acagaaaaaa ttgtctaaaa
    44641 aagctgataa ataaaggttt ttcttactat atttctattt ccttgacaga ataaggtttt
    44701 tatatttcag tttttttcac taaaaatcgt gaaacacgtc aataagtttg atgaacaaat
    44761 taatcattat ggtagaagtc gattgattta ttttaatgca atctctgtgg aattttcgaa
    44821 agatttattt ttttaataca gtctcaatat aactattcaa acataaaata acgttatttg
    44881 atttatttgt ttatagtaaa ttttatttag taatcattgc tttaaaatac tacgcttata
    44941 taacagagaa aataagcgtt ataataaaga acagtattat ttaaaatgac agaaaacatt
    45001 actattaaag aaataaaaaa cataaaaaat cttaagaaat cggtttcatt tagcttttga
    45061 gat
//
LOCUS       DAFLWQ010000012        44859 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.013, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000012 DAFLWQ010000000
VERSION     DAFLWQ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.013"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            212..604
                     /locus_tag="L1V16_000690"
     CDS             212..604
                     /locus_tag="L1V16_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1275052.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="L1V16_000691"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="L1V16_000691"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HBN1275053.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="L1V16_000692"
     CDS             3165..4775
                     /locus_tag="L1V16_000692"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HBN1275054.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="L1V16_000693"
     CDS             5067..5936
                     /locus_tag="L1V16_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HBN1275055.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="L1V16_000694"
     CDS             6101..7372
                     /locus_tag="L1V16_000694"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBN1275056.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="L1V16_000695"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="L1V16_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBN1275057.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="L1V16_000696"
     CDS             8763..9026
                     /locus_tag="L1V16_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBN1275058.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="L1V16_000697"
     CDS             9471..9920
                     /locus_tag="L1V16_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1275059.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="L1V16_000698"
     CDS             9977..11395
                     /locus_tag="L1V16_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1275060.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="L1V16_000699"
     CDS             11395..12255
                     /locus_tag="L1V16_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBN1275061.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="L1V16_000700"
     CDS             12429..13202
                     /locus_tag="L1V16_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1275062.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="L1V16_000701"
     CDS             13349..13714
                     /locus_tag="L1V16_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HBN1275063.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="L1V16_000702"
     CDS             complement(13862..15070)
                     /locus_tag="L1V16_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1275064.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="L1V16_000703"
     CDS             complement(15089..15367)
                     /locus_tag="L1V16_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275065.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15521..16216
                     /locus_tag="L1V16_000704"
     CDS             15521..16216
                     /locus_tag="L1V16_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBN1275066.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16658..17455)
                     /locus_tag="L1V16_000705"
     CDS             complement(16658..17455)
                     /locus_tag="L1V16_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBN1275067.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="L1V16_000706"
     CDS             complement(17452..18636)
                     /locus_tag="L1V16_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBN1275068.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="L1V16_000707"
     CDS             complement(18661..19908)
                     /locus_tag="L1V16_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBN1275069.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="L1V16_000708"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="L1V16_000708"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBN1275070.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="L1V16_000709"
     CDS             21888..22202
                     /locus_tag="L1V16_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBN1275071.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="L1V16_000710"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="L1V16_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBN1275072.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="L1V16_000711"
     CDS             22887..23531
                     /locus_tag="L1V16_000711"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBN1275073.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="L1V16_000712"
     CDS             23546..23875
                     /locus_tag="L1V16_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HBN1275074.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="L1V16_000713"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="L1V16_000713"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBN1275075.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="L1V16_000714"
     CDS             24863..25687
                     /locus_tag="L1V16_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBN1275076.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="L1V16_000715"
     CDS             25680..26027
                     /locus_tag="L1V16_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HBN1275077.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="L1V16_000716"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="L1V16_000716"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBN1275078.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="L1V16_000717"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="L1V16_000717"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBN1275079.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="L1V16_000718"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="L1V16_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBN1275080.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="L1V16_000719"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="L1V16_000719"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBN1275081.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31657..32451
                     /locus_tag="L1V16_000720"
     CDS             31657..32451
                     /locus_tag="L1V16_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1275082.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="L1V16_000721"
     CDS             32441..34483
                     /locus_tag="L1V16_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1275083.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="L1V16_000722"
     CDS             34764..34913
                     /locus_tag="L1V16_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HBN1275084.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="L1V16_000723"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="L1V16_000723"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HBN1275085.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="L1V16_000724"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="L1V16_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBN1275086.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="L1V16_000725"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="L1V16_000725"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBN1275087.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="L1V16_000726"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="L1V16_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBN1275088.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="L1V16_000727"
     CDS             39330..40412
                     /locus_tag="L1V16_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBN1275089.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="L1V16_000728"
     CDS             40412..41215
                     /locus_tag="L1V16_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBN1275090.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="L1V16_000729"
     CDS             41285..42025
                     /locus_tag="L1V16_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBN1275091.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="L1V16_000730"
     CDS             42036..43040
                     /locus_tag="L1V16_000730"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBN1275092.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44782)
                     /locus_tag="L1V16_000731"
     CDS             complement(43085..44782)
                     /locus_tag="L1V16_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275093.1"
                     /translation="MKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLE
                     KPLDEANLLIKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTL
                     TVSSPYQNYAGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMY
                     KQKRLEYSLILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYY
                     WSRMFYYKKWYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLAC
                     IGEAYKNNRFYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISY
                     NLIDHILNTDKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLM
                     HTDQTKAKNYVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLP
                     EELPINDDDLAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYD
                     TNLFSRGITEELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT        14421 a         7827 c         9341 g        13270 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtag ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcgaaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg tgcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataa
//
LOCUS       DAFLWQ010000013        44544 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.014, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000013 DAFLWQ010000000
VERSION     DAFLWQ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44544
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.014"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..132)
                     /locus_tag="L1V16_000732"
     CDS             complement(<1..132)
                     /locus_tag="L1V16_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBN1275094.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
     gene            542..781
                     /locus_tag="L1V16_000733"
     CDS             542..781
                     /locus_tag="L1V16_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275095.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            848..1057
                     /locus_tag="L1V16_000734"
     CDS             848..1057
                     /locus_tag="L1V16_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275096.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYRIHF"
     gene            1117..1788
                     /locus_tag="L1V16_000735"
     CDS             1117..1788
                     /locus_tag="L1V16_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBN1275097.1"
                     /translation="MKKWLFGFLGVTLIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPGYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            1841..3817
                     /locus_tag="L1V16_000736"
     CDS             1841..3817
                     /locus_tag="L1V16_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBN1275098.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYQVHAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GKGLSYVAEKADIKVTNNDGSVVLKENTDYKIENSDSGFVIDFIVNNGQVSDTVANLH
                     GQDLKMTYNMFVNDSAEIANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQSYVLISCLLLGAGGLSAVVYFKKKA"
     gene            3830..4585
                     /locus_tag="L1V16_000737"
     CDS             3830..4585
                     /locus_tag="L1V16_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1275099.1"
                     /translation="MIIRKPPKRRVMHKLMIFFWLLSAVAVYLIPVVETNVAKFQQQQ
                     RILAIENLEKTDSSLDVAKIELGDPVGVLTIPSISLKLPIYDGTSDKILENGVGITEG
                     TGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGQKFFIKVNEEQHAYQIYRIEEVK
                     AEELQKNYLDYLMPEKDQDRITLMTCTPKGVNSHRFLVYGERVSFSKEDLKLQKKAKN
                     RKSISLDWRLALLFAFFCVPIIFIYKKIRRRSE"
     gene            4582..5406
                     /locus_tag="L1V16_000738"
     CDS             4582..5406
                     /locus_tag="L1V16_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275100.1"
                     /translation="MNKRKWLFVCVAALFSTVAYSQLSFADSSDSSTTQTIDNSITAP
                     SETDSSENTTEETADSNISFTESTNPTSESSSETSEKPQDVEDTQVIKQAIHIQKIIS
                     SNQINNQGSQVAQQEGINGAKFIVYDITNILEEMSQDDNEKNQSVEIIESKLKDRAKK
                     LSYDQLKKVAEGETKTIDDQEGVIEFSIEVPANKKQAYYIVNESSPENISNSEDIVLL
                     TPVSNEKGEFLTDVWLYPKSEKSEPKEEIKKVVSTGVKKNFFENCWEFFAQLFFDN"
     gene            5707..7806
                     /locus_tag="L1V16_000739"
     CDS             5707..7806
                     /locus_tag="L1V16_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBN1275101.1"
                     /translation="MENKIHCTTGRVITLVLFLFLLLFARGTAVQALEKVDPSQIKEN
                     NNLVLYHDSDSLRNIEVTGINGFKILDEYSTKKQKVLAWPKVKDLKSTSKIVAHYQKV
                     GTYLGKEIDCDVTFSNFVAHAGVNQDGLAKTINGKKYYNYLLFDKNIYRGFFMQSINV
                     MNAKLEFKYAGTKTKVALSEPQPEIQSKMRSMRAAGIDLNDTFLSIYSLNGQYQQRVS
                     WYNDNNESVGERNIDMREFVGYEKMGSLPYFVTTDTACAEYKAPALSTNNLTSKVVGG
                     RAEKAYSSNDHFTDVVGADTYHRSGVTYTLQGASPTFMIGANTNSMMFSFDTALLWTP
                     QPSKPTKEVFNKANTEEAAHNIDKKVIPQGSDVYYHIHQKFDALTVNTMNKYKSFKIT
                     DTFDSKNFDMVSDGKNYDGALWYVEANGTWKKADTGGKLTVSGNTVTYTASDSFLANA
                     ANYGRDYILQLHMRAKNDAKGIAPNVATVTFNNDPNKGTQKTNTVENYFSLKPNKKVE
                     QDGKDVDGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDIASDHYKQFSIQDPVED
                     RLTYKEGSARVIDMSTGKDITSEGTLTYDSNSRTLKWEASADFLSKNLLDGREIQLIF
                     TAKTPLNEELDIDNQAKVSVESIEKATNVVTIGVKPNLPQIIVPKTGSNHLVLTVIGS
                     ILFLTLASLGYVVLKLK"
     gene            complement(7844..9901)
                     /locus_tag="L1V16_000740"
     CDS             complement(7844..9901)
                     /locus_tag="L1V16_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HBN1275102.1"
                     /translation="MKLFNPKTVLAIGTFAASLSLAGSVDAASTNVMYRLYNPNNNEH
                     FYTSSKKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVKSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNKLDSAYKGLKKKPVPTVNKAELQALYNRVKSTAKGDFTEESWNNFQTAL
                     SNAKKVLDDSKVSQTQVNNAKNSLDAAFKGLQHKPETPKEYMVTINHIDNQTGQVIAT
                     DQAKVTSGSTYTAKAKAFKYSEGAKDNFSYKVIGNDTQSKTITGNTTITFNYNQVHQI
                     NLLCNNNYKNEGRVDILKEQIINVTHGESVTLTAPSIQGYVLDDRVEPTNSVTLNNVT
                     ESQNYIFNYTRKFNVTVNHVNADTNAVLSSESKTVYEGDSFSTPWKNMTDQNYFLCRN
                     DDPTVTVDKNGQRSINNVDQNKTITFKYKKISLDELRNFMRQKELAWLNDYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENISQTGLYID
                     DLLSDDGAIDAMVGWKNSPAHNANLLYNNQSILGLGHNFVVDSAGRIGVDNVFISANP
                     IFK"
     gene            complement(10015..10227)
                     /locus_tag="L1V16_000741"
     CDS             complement(10015..10227)
                     /locus_tag="L1V16_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275103.1"
                     /translation="MYADKKKIEWLLFDSGKSVRSISIESGVPLTTVSDLANKRSSID
                     NMRFINAMKLNKLAEEIVDINTSTNK"
     gene            10414..10881
                     /locus_tag="L1V16_000742"
     CDS             10414..10881
                     /locus_tag="L1V16_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275104.1"
                     /translation="MKKKQLWFVSMFAIFFIILSGCSSNKKSEAKEDNSLLQPGTVWK
                     EEVGGLIHNLKIIDDTTWEYSESVWHPDPVQITVKRQKDYEGLERYKIVDSAGIREFI
                     NKPDSLFIVVPYEKDGVKKIIFLGSSKDEKRTKEKLIHDGSELNKYKLQKTSE"
     gene            10878..11120
                     /locus_tag="L1V16_000743"
     CDS             10878..11120
                     /locus_tag="L1V16_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HBN1275105.1"
                     /translation="MIASLFIYPEGGITVAKVKTPFEKAASKILERRGVSEIQWKKEV
                     LEKAQFDLLRGKDKDLEEYIYQREREKLVFDEIIKH"
     gene            11138..11440
                     /locus_tag="L1V16_000744"
     CDS             11138..11440
                     /locus_tag="L1V16_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275106.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAVAA
                     VASIALGGIFFFFGRRGAENGKTHVGYVLLGVGVILAAASIVVSMFSMFGQTPQGL"
     gene            11512..13566
                     /locus_tag="L1V16_000745"
     CDS             11512..13566
                     /locus_tag="L1V16_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275107.1"
                     /translation="MFFTISGNAKLDKELIRKATKKVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGPLDYQISEGFYPTLIDLIR
                     LDVFKDTDETMSVEESYRNEKLLQVLEEELESDQRKVNQVSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETDEVEVDPVEA
                     NEESTWTEGDFQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELGQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKVKEELNKEEQRVIEEEVQKVKERYEKKRDNAYSLCVE
                     KINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLEIRKREQD
                     LAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSESNE
                     VK"
     gene            13566..16178
                     /locus_tag="L1V16_000746"
     CDS             13566..16178
                     /locus_tag="L1V16_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBN1275108.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFSEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSLENETAKKLLIQFYEEQAADRLQEYVEKLIKNKEISEMI
                     GKRLLLESEKVVKE"
     gene            16175..18706
                     /locus_tag="L1V16_000747"
     CDS             16175..18706
                     /locus_tag="L1V16_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275109.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWIWNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNALFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PEQAKGMAGNDKSGLSDIQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYSSKPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEDKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKDND
                     QSFVHQSPAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            18758..19090
                     /locus_tag="L1V16_000748"
     CDS             18758..19090
                     /locus_tag="L1V16_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275110.1"
                     /translation="MDKYSNMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            19091..19684
                     /locus_tag="L1V16_000749"
     CDS             19091..19684
                     /locus_tag="L1V16_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275111.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            19847..21541
                     /locus_tag="L1V16_000750"
     CDS             19847..21541
                     /locus_tag="L1V16_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBN1275112.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEIVKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            22229..24106
                     /gene="ltrA"
                     /locus_tag="L1V16_000751"
     CDS             22229..24106
                     /gene="ltrA"
                     /locus_tag="L1V16_000751"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBN1275113.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            24237..24614
                     /locus_tag="L1V16_000752"
                     /pseudo
     CDS             24237..24614
                     /locus_tag="L1V16_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            24614..25819
                     /locus_tag="L1V16_000753"
     CDS             24614..25819
                     /locus_tag="L1V16_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBN1275114.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDP
                     LPFLNSSKK"
     gene            25835..26479
                     /locus_tag="L1V16_000754"
     CDS             25835..26479
                     /locus_tag="L1V16_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275115.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPTDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            26490..27296
                     /locus_tag="L1V16_000755"
     CDS             26490..27296
                     /locus_tag="L1V16_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275116.1"
                     /translation="MSKKKGERQRFKKRKSYLRWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            27318..27548
                     /locus_tag="L1V16_000756"
     CDS             27318..27548
                     /locus_tag="L1V16_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275117.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            28094..28369
                     /locus_tag="L1V16_000757"
     CDS             28094..28369
                     /locus_tag="L1V16_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275118.1"
                     /translation="MDLLIRNIEEKYINKIDKRCEELTVKTGKKWSRNQYLKVLIEND
                     FDHALLNYKKDQFDRLLEKFVDIQTYNTKTLEEYIATNNQLIGLLIE"
     gene            28411..28833
                     /locus_tag="L1V16_000758"
     CDS             28411..28833
                     /locus_tag="L1V16_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275119.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAEERVE
                     GKIKSNQTKKYSSKLKKPVNESVHTRVDPFDPTKILKR"
     gene            28852..30444
                     /locus_tag="L1V16_000759"
     CDS             28852..30444
                     /locus_tag="L1V16_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275120.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVISHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEIENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPEKRSEWNYGDENRTKLSPFTRGKLDELTKYVLTKEPGYQEYIQ
                     ISKALKEEAKSLYGESKRETKNAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVN
                     QMQSIYNERSFRTLKQLPTNEYKYSYQEFVKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            30456..30791
                     /locus_tag="L1V16_000760"
     CDS             30456..30791
                     /locus_tag="L1V16_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275121.1"
                     /translation="MKQYLDQWKVIEGSLKEERIEQLPDCLEKEHLFQISEMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEINEEGINNFPCESI
                     EESISLTEC"
     gene            30938..31132
                     /locus_tag="L1V16_000761"
     CDS             30938..31132
                     /locus_tag="L1V16_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275122.1"
                     /translation="MTQTTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQNGNI
                     LTLNLTTKMFVDAVENYPFV"
     gene            31164..33536
                     /locus_tag="L1V16_000762"
     CDS             31164..33536
                     /locus_tag="L1V16_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275123.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNNQFQKLFDHQKLTNGQ
                     PMNDKRNGRSWFNQQEKIENKIQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKEKDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSSEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            33597..35057
                     /locus_tag="L1V16_000763"
     CDS             33597..35057
                     /locus_tag="L1V16_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBN1275124.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFIPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            35068..37272
                     /gene="topB"
                     /locus_tag="L1V16_000764"
     CDS             35068..37272
                     /gene="topB"
                     /locus_tag="L1V16_000764"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBN1275125.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAESIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ENDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            37288..37437
                     /locus_tag="L1V16_000765"
     CDS             37288..37437
                     /locus_tag="L1V16_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275126.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            37511..38104
                     /locus_tag="L1V16_000766"
     CDS             37511..38104
                     /locus_tag="L1V16_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBN1275127.1"
                     /translation="MKDKIQCIFDKHNGNLSLKDARSEGLSPMTLDRLAEKDKIEKVA
                     PGFYTLKDAFVDELYLAQSIYSRGIFSHETALDLFQVGTYIPKKINMMFPKGYNVSKE
                     KLDQYAIQPHYTNKENFDLGVTETESFYGNKILVYDLERTLCDMWNPRYKASVEVKQE
                     ALKEYMTSTSRNTNKLRRYMDILKSPKEMTLYMLPLY"
     gene            38120..39019
                     /locus_tag="L1V16_000767"
     CDS             38120..39019
                     /locus_tag="L1V16_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBN1275128.1"
                     /translation="MTPTQFKEKTRNFAAEKHLNPQIVQRYYMMEKLLECIVESPYHD
                     DFVLKGGFLIGSKYGLENRSTVDIDTTYRNSKLTKEKLETVFSELTANPTKDGIRFEL
                     KGLTETREADYYPGFQAKFIAYLENARVPFKLDITSGDSIIPAALMYEHKLMFEDKTI
                     HIPAYPTEQILAEKLHATFSFGKDNSRMKDFYDLYMIPKLERIDEKNLYKSVQGTFKE
                     RNNQSVFKHLYDQEMPQLVKDEGLREKWKRYQQENYFAKDISFESTLTSVDSLMQSIV
                     EQEKAERKQNFKRSQQMNQEMER"
     gene            39022..39507
                     /gene="ssb"
                     /locus_tag="L1V16_000768"
     CDS             39022..39507
                     /gene="ssb"
                     /locus_tag="L1V16_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBN1275129.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFSLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRMHADQSSSSPSPTTFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            39873..40133
                     /locus_tag="L1V16_000769"
     CDS             39873..40133
                     /locus_tag="L1V16_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275130.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            40574..40780
                     /locus_tag="L1V16_000770"
     CDS             40574..40780
                     /locus_tag="L1V16_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBN1275131.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            40780..41031
                     /locus_tag="L1V16_000771"
     CDS             40780..41031
                     /locus_tag="L1V16_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275132.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYEIEYWLTKLEN"
     gene            41046..41483
                     /locus_tag="L1V16_000772"
     CDS             41046..41483
                     /locus_tag="L1V16_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275133.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFESIEKNGAFYTIESEEKDNE"
     gene            41476..42183
                     /locus_tag="L1V16_000773"
     CDS             41476..42183
                     /locus_tag="L1V16_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275134.1"
                     /translation="MNKVVYQLTTEDVSQFLTSKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNHLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGK"
     gene            42564..42743
                     /locus_tag="L1V16_000774"
     CDS             42564..42743
                     /locus_tag="L1V16_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275135.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            43084..43347
                     /locus_tag="L1V16_000775"
     CDS             43084..43347
                     /locus_tag="L1V16_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HBN1275136.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            43341..43691
                     /locus_tag="L1V16_000776"
     CDS             43341..43691
                     /locus_tag="L1V16_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBN1275137.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(43715..44329)
                     /locus_tag="L1V16_000777"
     CDS             complement(43715..44329)
                     /locus_tag="L1V16_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1275138.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRL
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
BASE COUNT        16357 a         7075 c         9063 g        12049 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaaatgata ttttacgagg aggaatagta
      541 gatggcgcga ccagttttag aggcgatgga tatggatact ttgacaaaag gaaggtatgt
      601 acagctgtta gctcgtggtt attcacctaa agaagtattc aaagccttat ctaaaggaac
      661 agatatggaa aaagaaagat tgcgaaaaga attcgattat tggagaaccc ataatggaat
      721 caaggatttg aaaccagcac ggccagtaat taaacgaaag aaaaagataa cccaagactg
      781 aagtgtagag cgtatgtgat cataggcttt tttatttttg caaaaaacaa ggaaggtagg
      841 aaaactcatg aattatgaag aaatcgaaaa cagaaaaaaa gtgtcgaaag aaatggaaga
      901 aaagttacta aaaacgatga agcaaaaaca ccttaaaaga ttatctgtcg cgcaatatat
      961 caatgatatg cagttaacag gaaaagagaa agcttgtttg ttaggttcaa tgaaaaactt
     1021 tgaacagttg agacgaactt atagaattca tttttaaaac tttttctatg gaaatgagaa
     1081 aaagtttttt tgttttgtct gaaaggaggc agatggatga aaaaatggtt atttggtttt
     1141 ttaggagtca ctttaatcgt cttttgcagt gtgtttggct atgttagcta ccaaaaacat
     1201 gaaggagagg tgtttaagca aaatatagaa aaaaagatgc ccgtagatca aatcaatgca
     1261 catgcaaaga gttataagga ggatgcaacg aacgtcaata atgatatgtc tttggggcaa
     1321 atgttgtcca tacaaaaaga agcaatcgaa atgggcgtca ataaacaagt atttgcacaa
     1381 attcagattc ctgcacttgg tttagcattg ccaattttta aaggggcaaa tcaatacact
     1441 ttgagtcttg gagcggctac ttatttttat gaagatgccg aaatgggcaa aggaaactat
     1501 gtcctagcag gtcataacat ggaaatgcca ggtgttttat tttctgatat tcaaaagttg
     1561 tcattagggg aggtgatgga cttagttagt aacgatggcg tctatcgtta caaggtaacg
     1621 cgtaaattta tcgtacctgg gtactttaaa ttaatcgatg gcgttcctga agagaactct
     1681 ttcttgtctt tgccaaagaa aggagagaaa cccttattaa cgttgtttac ttgtgtttat
     1741 acgtcacaag gaaaagaaag atacgtggta cagggagagc tacaataaca aggttttaat
     1801 caacgcgagt cgttgaaata tgaaatgagg agagtaaaaa atggcaataa atcggtatgt
     1861 aaaaaaagct ggaatgcttg ttggaatgtt aggaatcatt gcaggctgct ttcaggggta
     1921 tcaagtacat gcagaagatg tcacgcaaaa aacaccacca gagaaggtca atatcacggt
     1981 tcataaatta atgtacgatc aaggaacgca attgaatgtt gatattgacg ggatcaaaaa
     2041 cgatggttat acgcacgatc aatatcctac aggtgtaacg aaatacaaca aggcagatta
     2101 tggtgatgtt gagtttacgt taggaaatat tacggatcaa gtattaccga gagaagattc
     2161 tgatctaacc aacgcgaaag tggacgagat tgtacaagat gtagaagaca agggatctaa
     2221 cagtgagtac gtcaagaatg caaccaacaa aattacttca gctgtagatg aaaatggtga
     2281 gatcactttt actgatcaac cagcctatgt caattccaaa gggaatgtat atgtggttta
     2341 tgaaagtaaa tccgctgctg gattagtcac acaaaaagca aaaccaatgg ttgtgattgc
     2401 gccaatgaca gataaaacag gatcaggatt tttaaaaaat attcatttgt atcctaagaa
     2461 cattgtttct aagttgagtt ttgaattaac gaaatttggt gacgatggcg cagaccaaag
     2521 caaacaaacc cttttaaaag gggcaaaatt tgagttatac aagggcgaac ctggaaaagg
     2581 aacaaaattg ggtgatcttg tatcggatga tcaaggaaag ctgactgcga ctgatttgac
     2641 gttaggaaaa tactattttg tggaagttcc ttcggaagtt gtagtgggat cagatcaaga
     2701 accaacagca gatcaatatt tattaggcgc agacgctcgc aacgatgcgc acaataaatt
     2761 aacctttgaa attacgaatg atggcgtgac aagtgactta aaagcttcat acgtaaacta
     2821 taaagcacca gtgatcgata aaacagtaac aaatggaaca ggacaagaac attctttcca
     2881 aattggtgac gcagtaaatt atcaaggaac gattcatatt ccaacagaca ttgcaggtgg
     2941 cgcagacggt atcacagtaa acggtgtgaa aagcgaaact tctccttaca gtgtatttaa
     3001 atggggagat acagcaggta aaggactttc ttatgttgct gaaaaagcag atattaaagt
     3061 aacaaataat gatggttcag tcgtattaaa agaaaatact gactataaaa tcgaaaattc
     3121 tgatagtggt tttgtgatcg attttatcgt aaataatgga caagtaagtg atacagttgc
     3181 gaatttacat ggtcaagatc taaaaatgac ttataacatg tttgtgaatg atagtgctga
     3241 aatcgcaaat ccattaacaa atagcgtgga tttcgtttat aacaataatc catttaatca
     3301 ggaagaacac cacgaaaaaa cgaaagctga cgttgtgact tatggcgcaa aattcttaaa
     3361 agtcgatagc ggcctatttg gaacaggtat caaagcaaca ccgcttgaag gcgcagaatt
     3421 tgcagctaag aatgcagaag gtaagtacta cggtggactt actgatacag ataaagatgg
     3481 tgtcaaagaa gcagtttggg tagacgatgt agcaaatgca gcaatcctaa aatcagataa
     3541 agagggtcat tttgaaatca ctggtttaac tgaaggagat tactcactgg aagaaacaaa
     3601 agctcctgaa aactatcaaa aattaacaaa agagatctct ttcaaagtag acaaagattc
     3661 atacaaagaa gaaaaccgaa tcacgatcaa aaataatcaa aaagcttccg taccaatgac
     3721 tggtagcaac ggtttccaat cttacgtatt gatctcttgc ttgttgctag gagcaggggg
     3781 actttctgca gttgtttact ttaagaagaa agcctagaag gatcagctaa tgattattcg
     3841 taagccccca aaaagaagag tcatgcacaa actgatgata tttttttggt tgctgtcggc
     3901 agtagcagtc tatttaattc cagttgtgga aacaaatgta gcgaaatttc aacaacagca
     3961 aagaatttta gccattgaaa atcttgaaaa aacagattct tctttggatg ttgcgaaaat
     4021 agagttaggc gatcctgttg gtgttcttac aattccaagt atttctttaa aactaccaat
     4081 ttatgacgga acttccgaca aaattttaga gaatggtgta gggattacgg aaggaactgg
     4141 cgatattaca ggaggaaacg gtaaaaatcc tttaatcgcg gggcacagtg gactttataa
     4201 agataatctt ttcgatgatt tgccttcagt aaaaaaaggg caaaaattct ttattaaggt
     4261 aaatgaagaa caacatgcct atcaaattta tcgaattgaa gaagttaaag cagaagaatt
     4321 acaaaaaaat tatttagatt atcttatgcc tgaaaaagac caagatagga tcacgttaat
     4381 gacatgcaca ccaaaaggtg tcaactcaca ccgcttttta gtgtatggtg aacgagtttc
     4441 cttcagtaaa gaagatttaa aactacagaa aaaagcaaaa aataggaaat caatttcatt
     4501 ggattggcga ttagcactgc tattcgcttt tttttgcgtt cctattattt ttatttataa
     4561 aaaaataagg aggagatcgg aatgaataag agaaaatggc tgtttgtttg tgtagcagct
     4621 ctcttttcta ctgtagctta ttcgcaactg tctttcgctg acagcagtga tagtagtacc
     4681 actcaaacaa tagataattc aattactgca ccaagcgaaa cggacagttc ggagaatact
     4741 acagaagaaa cggcagattc aaatataagc tttactgaat caacgaatcc aacgtcagaa
     4801 agttcttcag agacttcaga aaagccgcaa gacgtagaag atacgcaagt gatcaagcaa
     4861 gccattcata ttcaaaaaat tatttcttcg aatcaaatca acaatcaagg cagtcaagta
     4921 gcccagcaag aaggtatcaa tggcgcgaag tttattgtct acgatatcac gaatatctta
     4981 gaagaaatgt cacaagatga taatgagaaa aatcaatctg tagaaataat tgagtcaaaa
     5041 ttgaaagatc gagcaaaaaa actttcatac gaccagttga aaaaagtggc tgaaggagaa
     5101 accaaaacga ttgatgatca ggaaggcgtg attgaatttt ccattgaagt acctgcaaac
     5161 aaaaaacaag catactatat cgttaatgaa tcaagccctg aaaacatttc aaacagtgaa
     5221 gatattgttt tattgacacc tgtttcaaat gaaaaaggtg aatttttgac ggatgtttgg
     5281 ttatacccta aatcagagaa atcagagccg aaagaagaaa ttaaaaaagt tgtgtcaact
     5341 ggtgtaaaga agaacttttt tgaaaattgt tgggaatttt ttgctcaatt attttttgat
     5401 aattaggatg aaatgatgaa aataataaga atattagttt ttaatctatc ctttttagcc
     5461 gcaacaatat tgtgttgcgg tttaattttt tctcaattat caatttatcc aagatatcaa
     5521 cgattgttca ttcattttct aaacattcaa tgtgcttcca tgccattaga ggtgattaaa
     5581 aagctcttga tcaatccaat ttttatggtt agtttggttc ttcttacagg attggtaacg
     5641 tgggtattag gaaaaaaaga atgaaaagct tacgatcgtt taaaaaaata ttagatggag
     5701 ggcattatgg aaaataaaat tcattgcact acgggaagag taattacttt agtgttgttt
     5761 ttgttccttc ttctttttgc gaggggaact gcagtccagg ccttagaaaa agttgatccg
     5821 agtcaaatca aagaaaataa taatctggtg ctttatcatg atagtgattc attgagaaat
     5881 atcgaagtaa ctgggatcaa tggatttaag atactagatg agtattcaac taaaaaacaa
     5941 aaagtacttg cttggccaaa agtcaaagat ttgaaaagta cgtcaaaaat cgttgcccat
     6001 tatcaaaaag taggtactta tctaggaaaa gaaattgatt gtgacgtgac tttttctaat
     6061 tttgtagcgc acgctggggt taaccaagac ggattagcta aaacaattaa tggcaaaaag
     6121 tattataatt atttgctctt tgataaaaat atttatcgag gatttttcat gcagtcaatc
     6181 aatgtcatga atgcaaaact agaatttaag tatgcaggaa caaaaacaaa agtagctttg
     6241 agtgaaccac agccagaaat tcaatcaaaa atgagatcga tgagagcagc tggtattgat
     6301 ttaaacgata catttctatc catttacagt ttaaatggac agtatcagca acgtgtgtct
     6361 tggtataatg acaataatga atctgtcggt gaacgtaata ttgatatgag agaatttgtt
     6421 gggtatgaaa aaatgggtag cttaccttat tttgtcacaa cagatacagc atgtgcagaa
     6481 tacaaagctc ctgcgttatc aacaaacaat ttaacttcaa aagtagtggg aggacgtgca
     6541 gaaaaggctt atagctcgaa tgatcatttc accgatgttg taggagctga tacttatcac
     6601 agaagtggtg taacgtatac gcttcaaggc gcttccccaa cattcatgat tggcgcaaat
     6661 acgaatagta tgatgtttag ctttgatact gcattgctat ggacaccaca accatcgaag
     6721 cctacaaaag aagtgtttaa caaagctaat actgaagagg cagcacacaa tattgacaaa
     6781 aaagtgattc cacaaggatc agatgtttac tatcatattc accaaaagtt tgatgcatta
     6841 acagtcaaca caatgaacaa atacaaatca tttaaaatca ctgatacctt tgacagcaaa
     6901 aattttgata tggtatcgga tgggaaaaac tatgatggcg cattgtggta tgttgaagcg
     6961 aatggtactt ggaaaaaagc tgatacagga ggaaagttaa ctgtatcagg taatacagtc
     7021 acttatactg cttctgacag ctttttagct aacgctgcaa attacggtag ggattatatt
     7081 ttgcagctcc atatgagagc aaaaaatgat gcaaaaggaa ttgcaccaaa tgtggctact
     7141 gtaacgttta acaatgatcc gaacaaagga acacaaaaaa caaatacagt agaaaactat
     7201 ttctctctta aaccaaataa aaaagtggaa caagatggga aagatgttga tggtcgaaat
     7261 gatggtaaaa aaggaacgcc tacagctcct ttaaatgcag gatctgaagt acaatatcta
     7321 gtcacacaaa aatggcatac aaaaggtgta gacattgcct cagatcatta caagcaattt
     7381 agtattcaag atccagtgga agatcgtttg acgtataaag aaggttctgc gcgagtgata
     7441 gatatgagta caggaaaaga tattacttca gaaggtacac taacctatga tagcaattca
     7501 agaacgctga agtgggaagc ttccgctgat ttcttaagta aaaatctttt agatggacga
     7561 gaaattcagc tgatatttac agctaaaact cctttgaatg aagaattgga tatcgacaac
     7621 caagcaaaag tttcagtaga aagtattgag aaagcaacta atgtagtaac gattggggta
     7681 aaacctaact tacctcagat cattgtgcca aaaactggat cgaatcattt agtgctaact
     7741 gttattggaa gtatattatt tcttacttta gcatcattgg gctatgtagt tttaaaactc
     7801 aaataaatat aaaaacaagg ctgagaatca gccttgtttt cttttatttg aagattggat
     7861 tcgcactaat aaatacatta tctacgccaa ttctaccagc agagtcaact acaaaattat
     7921 gacctaatcc gagaatactt tggttattat aaagtaaatt tgcattatgg gcagggctat
     7981 ttttccatcc taccatggca tcgatagcac catcgtctga taaaaggtca tcaatataca
     8041 gcccagtttg acttatgttt tctcccttag caccgtagca gcctaagctt tccaataaat
     8101 cttggaaagt accaccacca gggcgatagt gactgaagct gacttgtaat tctttagctc
     8161 gaatatctgc agcctgttga acaatatcat tgaattgcat tggggcaaca ccattttgtt
     8221 ggcgataatc atttaaccaa gcaagttctt tttgacgcat aaagttacgt aattcgtcta
     8281 atgaaatctt tttatatttg aatgtgattg ttttattttg atcgacgtta ttaatggatc
     8341 gttggccgtt tttatccacg gtaacggtag gatcgtcatt tctgcacaag aaataatttt
     8401 gatcagtcat atttttccaa ggagtagaga agctatcccc ttcgtatact gtttttgatt
     8461 cactagagag aacagcgttg gtatcagcat ttacatgatt aacagtcaca ttaaatttac
     8521 gagtgtagtt gaaaatataa ttttgacttt cagtcacatt gtttaaggtt actgaatttg
     8581 ttggttctac ccgatcgtct aaaacatatc cttgaataga aggagcagtt aaagtgacac
     8641 tttcaccgtg agtgacgttg attatctgtt ctttcaaaat atcaactcgc ccctcatttt
     8701 tgtagttgtt attgcacaac aaattgattt gatgcacttg attataattg aatgtgattg
     8761 ttgtattacc tgtgattgtt ttgctttgag tatcattacc aatcactttg tagctaaaat
     8821 tatctttagc accttcgcta tatttaaatg cttttgcctt agcagtgtaa gtagaaccag
     8881 aagtcacttt tgcttgatct gtagcaatca cttgacctgt ttgattgtca atatggttaa
     8941 tggtaaccat atattctttt ggcgtttcag gtttgtgttg caacccttta aatgcagcat
     9001 caagactatt tttagcattg tttacttgtg tttgagaaac cttagaatcg tctagtactt
     9061 ttttagcatt ggataaagca gtctgaaaat tattccaaga ttcttctgta aaatctcctt
     9121 tagcagttga ttttactcgg ttgtataaag cttgtaattc agctttattc acagtaggaa
     9181 ctggtttttt ctttaatcct ttgtaagcag aatctaattt atttttggca ctatccactt
     9241 gcttttgagt cgcttttgag tcatttaaca ctttcttagc attgtttaaa gcggtttgga
     9301 atgcgttcca ggtattgtcg gtatagtcac cttttttcgt tcccttaacg ctcgtataaa
     9361 gagcttctag agccgattta ttcactttgg gtttagaggt gtcagcgcca taccaaccga
     9421 taccttcgta tttccagcca tagtctttgg ttaaccattg tacttctttc caacttgcag
     9481 tgtagtgatg tgagccagat tttacaccag gaaggaaaag gcggtagatc ggtttattat
     9541 ttttttcggc agaacgccag gcaggccctt cataagtcca gccgtaattt ttagtcaacc
     9601 atttcacttc atcccaacta gctgtgtaat ggtgatcacg aagaccttta ttgtacaaac
     9661 gatagacaag atggccaccg ctagtcggtg cttcccaggc ggggccttca taatttcccc
     9721 attttatctt tactagatgg tcacgttctt ttttgctaga ggtgtaaaaa tgttcattat
     9781 tatttggatt gtaaaggcga tacatgacgt tagttgaagc agcgtcaaca gatccagcaa
     9841 gactaagtga ggcagcaaat gttccaatag ctaaaacagt ttttggatta aataatttca
     9901 ttttttcaac tcctaaattt aattaaaaat gtttacatga ttattatata tcggctaacc
     9961 gatatagtca ataaaaaata agaaaagcct tatataattt tggcttttct tattttattt
    10021 gttagttgaa gtattaatat caacgatttc ttcagccaat ttatttaatt tcatagcatt
    10081 tatgaatctc atgttgtcta tactagagcg tttgttggca aggtcactta ctgtagttaa
    10141 gggtacgcca gattctatgg atatagaacg aactgattta ccactatcaa acagcaacca
    10201 ttcgattttc tttttatcag cgtacatttc aatgctcctt cttgtttttt ctttattata
    10261 gctctttttt gtaatgaatc acaatatcaa gagaaaaatt ttctatagaa aggtggattt
    10321 ttatgagtat tcgttctccg tgtatccaaa tgaggtttgt tgctactttc gttatttgat
    10381 atactaaaaa taaacaacga aagaaggaat aaaatgaaga aaaagcaact atggtttgtc
    10441 tctatgtttg caatattttt tattatttta agtggatgtt caagtaataa gaaatcggaa
    10501 gctaaagaag ataatagttt attgcaacca ggaactgttt ggaaagaaga agtaggtggt
    10561 cttattcata atttaaaaat tatagatgat actacctggg aatattctga aagtgtatgg
    10621 catccagatc ctgtacaaat aacagttaag aggcaaaaag actatgaagg tttagaaaga
    10681 tacaaaatag tagattctgc aggcattagg gaatttataa acaaacctga ttcattattt
    10741 attgttgttc cctatgagaa ggatggcgta aaaaaaataa tttttcttgg atctagcaag
    10801 gatgagaagc gaacgaaaga gaaattaatt catgatggat cagagttaaa taaatacaaa
    10861 ttacaaaaga ctagtgagtg attgctagtc tttttattta tcctgaagga ggaatcacag
    10921 tggcaaaagt taaaacacca ttcgaaaaag ccgcgtctaa aatcttagaa cgccgtggtg
    10981 tttctgaaat acagtggaaa aaagaagttc ttgaaaaagc acaatttgac ctattacgag
    11041 gaaaagataa ggacttagaa gaatatatct atcaacgtga acgtgaaaaa cttgtattcg
    11101 atgaaattat taaacattaa aaggagcgaa taatcttatg tttgaatcaa ttacaatgaa
    11161 ttttttaact caaccgaaag tagtagctgc agttgatatt tttagagcat tacaaactgc
    11221 cgcaactagt ttgaaaaata atctgatgat ttttgctgct gttgcggcag tggcttccat
    11281 tgctcttgga ggtattttct tcttctttgg gcgaagagga gctgaaaacg ggaagacaca
    11341 cgtaggttat gtattgttgg gggtaggagt tattttagct gccgcttcta ttgtagtttc
    11401 aatgttctca atgtttggac aaaccccaca aggactataa aaaaaacaag taggaggagt
    11461 aaaaagtacg tggctacttt ttactccttt ttttatgaaa ggagaatatt catgtttttt
    11521 acgatttcag gaaatgcaaa attggataaa gagttaataa gaaaagcaac gaagaaagtg
    11581 ggaaagcgta cttccttttt accgaaaaca attaaatatt cggtcattga aacggaagaa
    11641 cagctacatg tgttaggaca agtgttagaa caagagaatc aatcttctgt taaattgact
    11701 ctcacgttac atgataaaga aggaaaaata gaaaaggctg gcacagaata cgtttttggc
    11761 ccactggatt atcaaatttc agaaggtttt tatcctacat tgatagattt aatccgcctt
    11821 gatgtgttta aagatacgga tgaaactatg agtgtggaag agtcttatcg aaacgaaaaa
    11881 cttttacaag ttttagaaga agagttagag agcgaccaaa gaaaagtgaa tcaagtgagt
    11941 gaagtcgaag taaatgaaga agtaccatgg gaacgaccaa tatttccaaa gaaggagtca
    12001 aaagaaaaag agacagtcta tgttgacgaa caagctgata ttccgactca gaaatcgata
    12061 tttgaggaag agaacgatgt gatgggtcaa ttggaggtag atccctttga agaaacaatg
    12121 gaggatgaag agacggacga agtagaagtt gatccagttg aagctaatga agagtcaaca
    12181 tggactgaag gggattttca ggaatatatt gaaccactta tcagtgaaga agtagaaaaa
    12241 aacgaaacag agatacaaaa ggcaactgta tttgattata ttttggatca atatccgcca
    12301 gagcatgaat ggatgaaaga aaaaaacaaa ttatttttaa atgagcttta ttcgaaatat
    12361 caattacccc aaacctatca agcattttta gagagtaaag aagaattaat ctcacagggt
    12421 aaaggcacac ttttagaaca gttagagtct gtccaatcaa caaattggca tgagcttgga
    12481 caagaagatt tattagccac ctttgaagaa cgtcaacaag aaacagatca agaaattaat
    12541 gagtatgcga cggaacagtc gtctaattgg gagaaagtaa aagaggaact aaataaagaa
    12601 gaacagcgag tgattgaaga agaagtacaa aaagtcaaag agcggtacga aaagaaacgc
    12661 gacaatgctt attccttgtg tgtagaaaag atcaacaatt ttactaagac gaatcaagaa
    12721 gcgttatcga aagaaaaaga aaacttgtta aaagaacgta ttaaagaacg aaaagaagag
    12781 ttctaccgcg gtttacgtac agataagcta aagattagca aagaattaaa tgaacaactg
    12841 aataagctat atcaaacaac gactgaagtt cttatggaaa aacacgaaca gatccagcaa
    12901 gaattacaag tacaaattcc aaaatggaaa aaagagtatg aaattcaaca acaagaattg
    12961 aaagaacaag aagaaaaaca acggcaaaaa gaaaaagagc gtgaacaatt agaaataaga
    13021 aaacgggaac aggatcttgc ggaacaaaaa atggcgatag aaaaacaacg gttagagcaa
    13081 gaaaaggaaa aagaagcagc tgctcgtaag gaacgtcaag aacaaatgga tacattgcgt
    13141 caagcacagt tgaattatct agcacaacct caaccagtag ctgctgttca aacgccagtg
    13201 aacaaccaag caaatttaac tccttcaccc cagcgttcct ttaacggatg gatggtggga
    13261 tgtattgcaa gtttaagctt gcttctaggt ggaggaacag tatttgcttt taatcatatc
    13321 aatcaatctt cacaggctga ttctgtagcc acaacggcgt caatcaagga agaagcccag
    13381 gaacaagcaa gaaaagagta tgaacaacaa ttagaagaat tattgaatcg taccaatcag
    13441 tcaacaacag agtcaagcat ggaaaatagc aaagagagtg attctagtaa ggctaaagaa
    13501 ggatcaagcg attcaactgt acaatcaaac acttccgaaa gttcagaatc aaatgaggtg
    13561 aaataatgcg tgttagagaa acaacgaagc gaaaagacaa acgattcaat ttagaaaaga
    13621 ataggtatct ttctcatttc tatcgctata ctccctcagg agaagagcta ccagaaaaac
    13681 atgacaaacg catttcgaaa aagatttttt atagtggact tgtatacctc cctttagagt
    13741 atttagtaac aagagtacca gaagttttca accgattgga aattgttaag ggaagcttac
    13801 aaggaataaa tctgtttcaa ttacaggaaa tgccacaggt ctttcatttt gattcagctg
    13861 gtttttggaa tccatttact cctacaacta gtttgggtac acgtttagca atttcgacag
    13921 tttgtgtggt tccagctgta cttatgggat tgaaaatgga catgtggttt cgtcctctag
    13981 cagatggaca aaaaggggat aatcgattaa tgaccttaaa agaaatccaa cagatttatc
    14041 cgcaaatacc tgaaacaaaa actacttttc caggttatgg aggtattcca atcacacatt
    14101 acaaaaaata ttggtacatt caaacagata ctgttaatac gtgtattgtt ggtacctctc
    14161 gatcagggaa aggtcagatt gaagtgttag ccaccattga caatttatct cgtgcagaaa
    14221 aacaaagttc aatggtcgtt aatgatccaa aaacagaatt atatgttggt agtaaagatg
    14281 aactagaagc tagagggtat gatgtatatg cctttaatat caccgatcca ctgcaatcaa
    14341 tgagtgataa tccattggca ctcatcgtga aatactggaa acgaggagac atagatactg
    14401 caacacagtt aaccaatact ttcacaaata cgatttatta tgatgccaac gcttcagata
    14461 acaaatactt taacgaaaac gcgcagaaag ctgtcaatgc gcttattttt gcgttgttag
    14521 aacaagctga tcaaacagga gattactcca aattgacacc gaataatctc gttgagcttc
    14581 tttctgagat tggcggtttt aattattatc cagatccaga caatgaattc aaacagttga
    14641 atgccttaga tgaatttatg aatcagttgc cacctggaaa cattgcaaaa aaacaatatg
    14701 gggcaacgaa aattggatct gataaagcga agggaaatat tttatcaacg gcaatcacgg
    14761 gattgaatcc atttactcta acgaaaattg caaagatgac ttctcaatca acgattgatt
    14821 ataaatcggt tgggtttcca aaatacttag atttgaaatt acatgaaagt cttttaaatc
    14881 aacgagtcgt agtagaattt tatcataagg gaaagaaatt tcatgaagaa cgtgtcaaag
    14941 taggctataa aggatttagt gaaatcaatt ttgattgtca tttagttgca ggtgatcaag
    15001 tttgtttaaa atacgatcat caaggaaaag aatatgtggc ttggtatgaa ttttctcaaa
    15061 gagtattgaa agacgaagag ggtaatatcg tttatcggaa aaaacgagga gaaacccatt
    15121 tgccagaatt agaaaaagaa gccgttctaa cattagatga ggaaaaaagt aacttattag
    15181 tagagtctat tcggatgcac tataccgata aaccaatggc tatttttatg cttacacctg
    15241 attatgatcc atctaaccat atcattgtta gtatttttct tagtcagtta tataaagaat
    15301 tatctacgca atgtgttaag actaaaggag ataaatgtca ccgcaggatt cattttattt
    15361 tagatgaatt tgggaatatg ccaccaatgg ataatatgga aggaatcatg acggtcacag
    15421 ctggccgaaa catgttgtgg gatctgttta ttcaatctta tcagcaactt tatgcgaagt
    15481 atggagaaca aaacgcagcg attatcaaag aaaattgtca gacacatatt tatattatgt
    15541 cgacagatga taataccatc gaagaatttt ctaaaaaagt ggggaataag acggttgaac
    15601 aagagaacag taccatcaat tcattaggta tgaatactca tatcaatcgc aatgttgatt
    15661 cagatcgtat cttaactcct gaaagaattt ctactttttt agaaggagaa acgattgtac
    15721 tcgctccttt aaaacgacaa gatttgaaag gtcataaaat acggccgtat cctattttta
    15781 atcatgggga aacgaatctt ccttatgctt atcaatatat tgaagatttc aatccatcgt
    15841 gggatatcaa tgatatagac atacattgta cacatgcgga cttggatctt aaggctttac
    15901 aaattgatta tgattatttc ctaccagatg aatatgctag aaatctctat catggactgc
    15961 atgatcaatt agaagaaaaa aacgaagaaa atatgtttta taaaatcgtt caatctcttg
    16021 agaatgagac ggctaaaaaa ttgttaattc aattttacga agaacaagca gcagatcgac
    16081 ttcaagaata tgttgaaaag ttgatcaaaa ataaagaaat ttctgaaatg attgggaaac
    16141 ggttgttatt ggaatctgaa aaggtggtga aagaatgatc attggaggaa ttttttctgg
    16201 catagccgac tggtggtcag gcttattcgg agaaggggat gcaaacccca aaaccgtaac
    16261 gaaagtctta caagattatg ggaattatct gcagtatcaa gatgtattta gttggatttg
    16321 gaacactttt ctgtggggat tgattaaagg attatataat ctcaatactt tactagaaaa
    16381 aaccatttat caaagctttg atttaaaaga cttattgaac gccgctgggg taaatgcact
    16441 atttcaaagt ttgattagta aggtattggc tcttttttgt gtcgtcacat taatttattt
    16501 aggcttgaaa ttttttatga gtaaacaccc accaaaagtc aaaaatatct tggttaattt
    16561 atttatggcc atgatcttga tttttggtgg tagttcttta atcgatgaag ggttaaatat
    16621 cagtaaaagc ttttacggag acgtcactgc agcaaataaa gcagataaaa cgggatcacc
    16681 tgcttttcaa attattcaaa ataatgtgat cgatgtcagt acgttactag caactgaccc
    16741 gaataaagta gaatccctac caacagataa aagaaatgct ttaacagcga aaaattttaa
    16801 aacagcgaat atcaatggga ttattactcc tgaacaagct aaaggtatgg caggtaatga
    16861 taaaagtggg ttatcagata tacaaaagga tcggttaaag gcattacaat accgattgga
    16921 actagatgat aatgggaaag aaattcctgt tcaaattagt gacgaaggct tagcaaaata
    16981 tgtctatact tcagggtatc gtcgatacag tagtaaacca ggtattattt tagctggtga
    17041 atcttctttg gcagtagcct atttatttat cctatttacg atcgttactt gcattattga
    17101 gctggtattt aaaaaattct atttagtgat tgccgcgtca acggactttg agacaggtca
    17161 acggatgaaa agtgcgatag aagatatttc tcaatccttc ttgttattgg cgtttacgat
    17221 tttagaatta cgaatctata ccttaatgct ttcaggtatc ggtgatttgc atgcggcagg
    17281 aaagatcaat ggattcttgt atgtcgttgc tttgattgta ctaaccattg cgctattcaa
    17341 aggctctcaa tcagttacga aaattttcgg cgttgataca agcctgaaaa acggcagtaa
    17401 ttctcttctt agcatgtttg ccttaggaaa tattgcgaaa aatgtgggta gcggagctaa
    17461 aaaccttgca agtgctggta agagtggttt aagccattta aatgatattc gtaaaaatgg
    17521 atttggccat cgaaaagatg ttacccctga taacggggaa gaacaatcag acgataaagc
    17581 tacaactgta cctaatagta agaaaacagt ttccgaaatg ttcgggaaag cgaaaaatgg
    17641 tgtttctaaa gccgcagaag gtcttggtta cgtcaatgaa cgtgggttaa aaggaacagc
    17701 tgaagatctt acagaaaaag ccaaagacac cttagaagat aaattagacg gcacgagagc
    17761 taaagaattg gctgaagctg tgaagaatcc atccgaagca ctagaaaaac aaaaagaaaa
    17821 agcttcagaa gtcaaagaag gactaaaaga tgcgtatggt gaaggacaag tcaatgcagc
    17881 agtgaaagct aatacaacaa ccgaaaaaga aaatcaagaa ggtatagtga ttccttcagt
    17941 caaagatcac caagaagcgt tgcactctaa tgaaaattcg attgaagaga aaaattccat
    18001 agaagaaaga aattcagaag aaggaaaaaa tggacagtta ccaaaaactg atccagaaca
    18061 atatcgctat aaacctaaca gtgaccttga aaatgagaag cgaatttcag atttatcaaa
    18121 agtaaatcaa gaagacaaag cagaaaatga gggacagtta ccaaaaactg atccagaaca
    18181 atatcggtat agatctgtta actccgaaaa tgaaaaacgc atttcagatt taccaaaacg
    18241 aaatcaagaa gtacaaacgg atgaggattc catcgttctg ccaaatgata atggaatcga
    18301 agttggaact gaaaaatcaa cgaaaattgg tttacctaag gcacaaaatt taccaatgaa
    18361 agatagtcgt ttgaatcaat tcaaggataa tgatcaaagt tttgttcatc aatcacctgc
    18421 aggtactgtt caaatgaaac caagtcgttt gcctgaaaat ggaaatctga caactgtttc
    18481 ttacaattta tctgaaagtg gtgagacagg gaatgcgtcc gttcaaaatg ttgtgacaag
    18541 agaagctgca ccaaaaccta ttcaaaacgt tcatacaggt tacaagccag caaatgtggc
    18601 atttactgca ccaacaaaaa taaatgtgac aagagaaaca aaaaacagga acaatgcatt
    18661 gaaagaacaa ctattgaggg atatcaaaca ggatatcaaa ccataaaagg cctacaagtt
    18721 aggccttttt tctatgtatg aaaaggagaa atcatttatg gataaatata gtaacatgaa
    18781 aaaccctcca agatttagtg gagaatggaa gtttttcgct tttttctttt tagatctatt
    18841 aacgcttggt ggctgctttt tttgggcgaa aatggtcaat aatcttgtcc acttaccact
    18901 cttttttgca ctcttgaatt atggcttatg gattgcgata gcgttagtga ttgtttggcg
    18961 accctataat aacccaggtc aacgacaaat ttttgcgatt atcgagtcta ttttttttgc
    19021 ggacaagaac cattatcatg cgttagatcc taaccgaaat tatcatggta cgtataagga
    19081 ggatgaataa atgcgagtca aaggacaaaa ttcagttgaa aggaaatcca ttttgcagtt
    19141 tggaaaacca gaagagcgct ctatcttgga cttatttcca tataaatcct gtacagaaga
    19201 gggagtctta attactagag aagatcattt tcaacgttat tatcgtgtag tttctacaga
    19261 cgtggaagga ttaaatgaac aagagaaact agaacgaatg aatcagttga ccaccgtcat
    19321 gcgtacgtat gtgccaacaa ttaagttagt tagtttgacc acagagacgg atctaacgga
    19381 acaaatcgtg caaaagcggc aattattaga taaaaatcgt atggaacagt ccttaggaag
    19441 aaatctacaa cgattaaaaa aatatgaaaa gaaattagtc gaagaaatcc aggaattgaa
    19501 acgagcagaa caagaacgtc ctgacttaag cttctttttc gtcattgaag gaaagacaat
    19561 caaggattta caaaccagaa accgtcagtt aatgcgatct agtggcattt tagggttaaa
    19621 accactctac aaaaaagaat tgatcaagat tctgtatcga atgaacaata tgaatgatga
    19681 gtaggaatgg agaagagaga atgaaatatc cgttgatatg gttagaaaaa gatgttccga
    19741 aggaagagac cactagaaaa tttcctcaca ctttaagcct gggtaagttg ggaaaagggc
    19801 aatcttttaa ccaagtaaag aatcaaacaa gaagaggtga ctgtacatgt tagaagcaat
    19861 taaaacagct ttttcaccac aaaatgatca aaaagtactt gatccattaa agcaactagg
    19921 aaatcgggaa atagaaattg taaaatccaa agggtatgat ttagattttt taaaacaagt
    19981 gatgccacaa ggtgggttaa attttgatga agaatatgtg acgtatggta atggttattc
    20041 acgatgtgtg acagtttatc actacacaaa aaatcctacg cttttttggt tggccaatct
    20101 catgaacaat cctcatacag tggccacact cgatgttagc acagatgaaa agcaaaaagt
    20161 gattgatcaa atcaatcgtg ccttagatga attaaatgat cgatcagata atgaacgaaa
    20221 agcgactgac cgaaataaaa gcgcggaaga atacctggaa ctagcggaat atgctagaaa
    20281 attgacttct aatggggaaa tttctaagca agtcaaagtg agagtacatg tttacggaaa
    20341 cacgattcaa gaagtagatg aacgagcgca ggaactgatc gaaaatctca aagggatgga
    20401 ttatcgtgcg gtgacttatc tgcataaaac caaacgagat tggcaatcga tgtttaccat
    20461 gttcgatgaa caagctgaat ggttcggaaa tatcaaaggg caatcactac catcgttaaa
    20521 cattggcgga ggtttcccgt tccaccacca aacgctaaaa gatccaggag ggacacaata
    20581 tggggaaacc atgacaggcg gcccatttgt ctggaatgcg acgtataaaa atagtgtacg
    20641 gttgtctact aataccttgc ttctaggaat gatgggagct ggtaaatcga ccgttcttaa
    20701 aatgatcgcg gaagcccatt tagctgcagg agactttatt tggggctttg aaaagggaaa
    20761 agactttatt cctttcttaa aggaatataa cggtattatg gtgcgtttag acggatctga
    20821 cggaatgatc aatcctttag agatatttgc cacacggacg tatgatgaag catccagttt
    20881 atatgacgat ggatcagtca aagatttgaa gatcaatgaa gcagcgtcct atcaaacaca
    20941 cttagacaaa gtggtctatc aggtacagtt agtgagtcct cagctaaaag gaacgatgaa
    21001 agcagaattt aagacctact taaatcgttt ttatgaagag tatggaacag taccacgcgg
    21061 ctttacttcc tcaaattcgc gttcaaatac tgatacgcaa gtcacaggga aagatccaga
    21121 agcttatccg acgttcaaag aatttttaga ctttttagga caactggaat taccaggtgc
    21181 ttcccaagag aaaaagaatc gaaaagaaga aatggaatcc atcgtagaat ccttatgtga
    21241 gacgtatggc atgatttttg atggtcatag tacgattcga caccttgacc aacaacagtt
    21301 ggtctttttt gacattgact ctattacagg cttagatcga ggggtacaac aatgtcaaat
    21361 gtacatggct atgacgttga tttggaatca ggcattgatt caaggaagaa gacaacgacg
    21421 tttaattaaa gaaaaacaaa tggaagaaca agacttcaaa cgcttcttgg cgatgattga
    21481 tgagtgccat aatggtgcga cctgttctgc agtgaaaagc tgtgggttgc aagtagtcta
    21541 aaaactattg taataactct tataacgaga agtcaaatga gtgggtaacg ccacaaaggg
    21601 cttccactga tactccgaca tgcaacaagt agtttatgca gaccaacgtt gtgtgaagct
    21661 cggtgaagtc ggctgaagga taccgtaagg taaaagaaat agtgaatacc acgaaagttc
    21721 tctagaggta aagggtgtat ccgataagtc gggtgtccaa aaaaacttaa tatggtgagt
    21781 atgtacaaac gtactgacga actagcgaat gtactgtccg aaaggcatag ctcctagaaa
    21841 tgggagagac agtgagcaaa aaatcactca ttgtgctaac ttgtggttga gtaaaagtcg
    21901 ttgttatgaa agaccatgct gcgttacagg cgtaggagaa gttagggggc aaaagctagc
    21961 atctaagtta aggcatgtgg atagatataa gggaacaggg gaagccatca acatggagag
    22021 tgcatactcg atgaagtggt agtaagaaat atgtgaatga caaataactt actttagtga
    22081 tggtgaaagt agagtcacga ctgatgaagg ttctgtaatg gaactggagg aacaggctcg
    22141 attcgtctgt aaaagtcatg aaacccgttc aaccatggga ttctcgtatg actaaaaagg
    22201 tcacgagcca attggagcgt gataaaccat gacaaaagaa acaagtccaa aagataggaa
    22261 gttgcggcat gcagaatatt atggcatgac ggaaatcttc gataagatat actccaaaag
    22321 tttgaaggga gataatttca agaatctaat gcagattatc atttctgata acaacattgt
    22381 cctagcatat cgtaatatca agagaaatca cggtagtgtg acaagaggag aagatggagt
    22441 aacgattaaa gatattgaaa atctcaaccg taatgaattc gtagaaattg ttaggaagcg
    22501 attcgcacat tataaccctc ggaaagtaag gcgtgtagaa attcctaaat ataatggtaa
    22561 attaagaccg ttgggtattc catcaatatg ggatagaatc gcgcagcaat gcatcttaca
    22621 agtattagaa ccaatatgtg aagcaaaatt caataatcac agctatggtt tccgcccaaa
    22681 tagatcagca gaacacgcaa tagcagattg tatggcccga atgaatcaaa gtcacatgga
    22741 atatgtggta gatgtagata tcaaaggttt cttcgacgaa gtcaatcata ctaaactcat
    22801 gagacaaatc tggtctatgg gtatacgaga caaacagctt ctcttaatca ttaggaaaat
    22861 gttaagagca cccgtagtac ttccaaatgg gaagttgata tacccaacaa aaggaacacc
    22921 acaaggcgga atacttagcc cattacttgc gaacatcaat ctcaacgaat ttgactggtg
    22981 gatagcaaat cagtgggagg aaaaagatgc caaagagcta aaacatcatt ttaggaaaaa
    23041 tggagcttgg gataaaggta atatctatca caagctcaga aagagtacaa ctctaaaaga
    23101 aatataccta gtgagatacg cagatgattt taaaattttc tgtagaaatt ataatgaagc
    23161 gaaaaaagtt ttctatgcaa ctaaaatgtg gttacaggag cgtctaaagt taccaatatc
    23221 tgaagaaaag tcaaaaatca caaatctttc aaaagaagaa agtgaatttt taggctttac
    23281 gatgaaatta gtgaccaaag gtaacaaaaa ggttgttaat acgcatatag gtacaaaagc
    23341 acaaagcatg attaaagtga aactaaaaaa acaaatcaaa cgaattcaaa aaagtcctaa
    23401 tagcaaagat acctttatct atattggagt ctataacagt atggttattg ggattcataa
    23461 ttacttcaaa attgcgactc attgtagtgt agcaatgcga aaaattgcaa gagaactcag
    23521 accaagtttt gaaatacgac tacgagaaca aggaatctca aaagaaggac aatacggaaa
    23581 gtacgaagga tacaagcctt acctacggtc aggacaaata cgatatataa gagggtttcc
    23641 aatattacca gtagggtata ttcaacacag acatccgatg tgtaaaaaaa gaaatattaa
    23701 taaatacacc gaagaaggta gggaagccat tcataagaag caacaaaccg tagaagaatg
    23761 gaagatatcg tggttgtgta gcaatccagt gcttagtaag agagcaacga ttgaatttgc
    23821 ggacaatcga atttcaaaat tcatcgctca aaagggaaga tgtgcagtaa caggtgagga
    23881 gcttatctta tctgaaatgc attgtcatca tattatccct tatcatgaaa gcaaaagtga
    23941 tagctatgaa aacctagtga ttgttactga ggaggttcat cgggtaatac acgctacaca
    24001 aagtgaaacg attgaggaac ttctaaaata tctaaaatta aatccaaaac aaaaagaaaa
    24061 actcaatgag ttgagattaa aagttggtaa cgaagaaata tcttaataaa tatttgtagg
    24121 acgggaaaac agaatgtctt ttatagacga gggaacgccg tatgcggtga aagtcgcacg
    24181 tacggtgtgg actgggggaa aagacggaga taatatcaaa ctcttaccta tcagtatcga
    24241 ttaatccaga ttttattgaa acggtaaatt atgtcacaaa ctttcaacga gaaatgcgta
    24301 aagtagaagc aatgactgtt ttagctacac aatccccaca agaaatggtg ccagaaaata
    24361 tgtcttctga taacttctcg aaactgaaga aagtctttga attttcttct acgaagatct
    24421 ttatgcgtat ggatgaatct attttacgtc atatagaagg attagtgggt aaatcaatga
    24481 cgaactcaga attagaatcc attcctcaac aaaatcaagg agacgctgtg atcaattttg
    24541 gctcaaaaga aaccattcgt gttcatttta gtccgaacaa acgtcaatta aaattgtttg
    24601 atggaggaaa ataatggaaa accaaaatga aagtttaatc aagcagtatg ttaagcgtcg
    24661 tgcaaagcgg cgcttatttt tgtggttgtt tggtacttct gcaggtttga ttactatttt
    24721 gatcactgtg ttcgtgaccc tatttctaat acttgcggcg ggctcgattg ataattcgga
    24781 ttcagattca agcagtggtg gcgaagcttt tacaggagaa tattcggaag gcttaccgat
    24841 ttataaagaa atcaaaggaa gaggcccttt ttctgatgag attgcgcaat atgccgtagg
    24901 tgcagcagtg aaatataaat tattaccaag tgtgatcctt tcgcaatacg gttacgaatc
    24961 agcgtttggt acatcggcgt ccgcaagaaa tgatctcaac tattttggga ttacttggtt
    25021 tgatggttgt ctgtttccta aaggaactgc acgaggaatt ggtggcattg aaggtggctg
    25081 gtacatgaag tttcccaact caaaagctgc attttcctat tacggcttta tggtagccac
    25141 acaatccaat tttaatgctt gtgtaggaaa taaaagccct ggcgcaagct tattgatctt
    25201 aggacgaggc ggttatgccg ctgcaggaat tacggaagat agtccgtatt atacaggttg
    25261 tatgtcaatt atcacttcta ataaattaac cgaatatgat gaattcgcca tcaaacattg
    25321 gggtgaaggt ggcaataaca acggcacgat tactggtgaa tggacgaatc cattccctgg
    25381 cagcagttta gataaaagtt ccttcagcgg tggtcaatta tttggaacga atccaggcgg
    25441 tgaattccgt ccgaacggct tccatgatgg attagatttt ggttcagttg atcatccagg
    25501 aagtgagatt catgcggttc atggcggaaa agtcgtgtac gttggcaatc ctggtatttc
    25561 aggtttgggc gcgtgtgtga tcgtgattaa ttacgatggc ttgaatatgg tgtatcaaga
    25621 atttgcaaat agtacaggaa attctcgagt gaaagtaggc gatcaagtga aagttggtca
    25681 agtaattggg atacgagata cagcacactt gcatttagga tttactcgaa tggattggcg
    25741 tcaagcacaa ggacatgcat tcattgatga tggtacatgg atcgatccgt taccattttt
    25801 gaatagcagt aaaaaataga tcaggagaaa aaatatggaa aataaaacgt taaaaatcgt
    25861 cttaacagct gcaattagcg ttagtttaat cggcaatatt gcgttgtttt ggcagctgaa
    25921 agaggaacaa gcagcaaata cctataaaat tgaagaagtg gctaaaaacg cgtctgagaa
    25981 gctcaaaaaa aattcctctg aggcacaggc gaagatcgac aagttaaatc aaaccatcaa
    26041 tgagaaaaac caagaaatcg atcagctgaa gcaacaagat ggcacaaaag caaaagagga
    26101 agtaactgaa gcacaaagaa agacggcaga agagttcggt caattggcca ttgataaatc
    26161 attaagcaga aatgaattaa cggaaaaact aaaagatgtc gcaacccaag aagtgatcga
    26221 caaattaagt cctacagacg atgatcacca acatgatgat tacggaagtt actcctttac
    26281 attaggtgac gtgcaaactt acgctcaaac aagcagtgta aaagaggaac aaaattttgt
    26341 cgtatttgtt gattatacaa tcggcaatcc gcaattcaaa gatgtcaaac cacaaaaaat
    26401 aaaaggtgga ttaactgtca ctgaaaaaca agtagatggt caatggaaag tcatagactt
    26461 tagttatttc actcgttagg aggaagaaaa tgagtaagaa aaaaggagaa agacaacgtt
    26521 tcaaaaaacg aaaaagttat cttagatggc tgggaatctt tatgattctc ggctttttga
    26581 ttcttgctag tccgatttat acgaatcaga aggtagatat accagatgag gtaagcacga
    26641 acgccttttt aaacacgaaa gagctgacaa tggtttcaaa agaaaaagga gcgaaccagc
    26701 aattagtttt tgaatttgcg atcgatgatg aagatcaaag cttgttaaaa gaactggcta
    26761 atcttaatta tcgcgtagaa gtaaagacag ctaaagggga ttatcaagca atacgagcca
    26821 aagtgattaa ggtgtctgat gattattttg cagtgaagct aacgcatgta ccagaagaat
    26881 atatcgccat gcgtttaacc attattcctg aaaaaattga tccaaaagtg gatatgcaag
    26941 aaccacaaga tctgatttat tacgtgcacg aagataaggt taaagatcaa gtgaaagatg
    27001 aagattatga acaacacgcg atcaattaca aagtgaaagg atacaagaaa gaacaaaaag
    27061 cagctcaaaa acaaatggaa tctttccaag caaccattga tttgaatgaa gaattagtga
    27121 agaagctaaa agatcaattg ccttatcaag tcgcagatga tcaggaaaat actgaaaaca
    27181 agattaatag ctaccagcaa gaaattgaaa catcgaaaac gcaactgaaa gatcaagaag
    27241 agatcattca aaaacttcaa gaaaaaattg atcgtatgac aaaagaaaag atttagaagg
    27301 acaggtggag tgaaaaaatg aagcgaacaa acttggctga caaagatact ttcgctgagc
    27361 agaaagtatt gattaaagcc tatctcaaag ttgtaaaagc taaagaaata tgtcgagaag
    27421 tgaatttatc taacacaaca atatctgagt tgaagaatgg tcgaaagaat ttagatactt
    27481 taaaattcag atcatttgaa gctctatatg tagctgctaa aaaatatttt acagctgata
    27541 acaaataaaa aacaggagta ttttatgtga aaaaagtata taaaaaatgc ttatgaatca
    27601 gctatatcac cttaaccatt tgttaatgag atgggagaaa acattaacca cgattctaac
    27661 gcaaacatca agcacataaa acatttaaca ctcctccttt ctggctgaag atttcaacca
    27721 aacaggaaga cagcgtatca attatagcat acactttttc ttaaattcat ttttcatatg
    27781 acaaaatatt tccttctaat cgacaaagtt agaaggattt tttattgtct aaatacacaa
    27841 ataaccttaa tttttaaaga gcataaggaa acgtgatatc actttctcac gaaaggtgtt
    27901 aggtaggctg tgcctaccac gtttctaaga aagataaatg atatcaaaat tttggatttg
    27961 tgtgtagatt tgtgggtagg atgaaagcga atgtgggcag taaaataagc gtttgtgtgt
    28021 agcaaaatca aaaaatgtgt agggatatgt gtagctacac atatccctac acataataaa
    28081 tttggaggaa aatatggact tattaattag aaatattgaa gaaaagtata ttaataaaat
    28141 tgacaaacgt tgtgaagaac ttacggtcaa gactggcaaa aaatggagtc gaaatcaata
    28201 cctaaaagtt ttgatcgaaa atgattttga tcacgctctt ctgaattata aaaaagacca
    28261 atttgatcgg ttgttagaaa aatttgtgga tattcaaact tataatacga aaactttaga
    28321 agaatatatt gcaacaaata atcaattaat tggtttgtta attgaataat aaaaatagta
    28381 ttgtgaattt ataaaaggag gaaatcaatt ttggcaaaag caacaagaaa acatgtatat
    28441 ctttacgata tgcatatcga agtacttgat gaaataattt ctactcatga agatatatct
    28501 aattatagtg aagcagtcag acatttgtgt atgatgtatg atccaaaaat cgaagaaaaa
    28561 ataaatccaa ttcaaattaa attgaatgca atgggaaaag aaatttctat tttaaccgaa
    28621 atggtttcag agtttgcgga tcttcatttg aaagatacag gaatactaat tggtacaaat
    28681 tcaactgttt atcaagaagc agaagaacgt gtggaaggaa aaattaaatc caatcaaacc
    28741 aaaaaatatt cttctaagtt aaagaaacca gtgaatgaat ctgttcatac cagagtagat
    28801 ccatttgatc caacgaagat tctaaaaaga taaaagtaga aggagaacgt gatgaataaa
    28861 tcgcctgcag ttattcttac ttgtcaattt accttgccca ataaaaaatc tttttcaaca
    28921 tacattgatt atatgacaag agaaaaagca ctggaagaaa tggaacgacg tacgcccgaa
    28981 gaagaacagg aactgcaacg aatcaagaat gctttagagg atttttatat tcctgaagga
    29041 gaaacttttt cggaaagtaa gacggataaa gaattcagtg aaacgtcgaa tgaagctcaa
    29101 tcgttgatgg aacatggaat caattttgac aagttagagg aacaagattt taccaaatat
    29161 ctttcttata tgacccgtca ctatgcgtta gaacaaaaga aagaactgac gcaaagggaa
    29221 caaaaagaat accaacggtt gaaccaagca atgaaaaaat atcaaacaga gccacataaa
    29281 aaagcttcag gaaatcttcc tggagttttt tctatggctt cagacgaagt gaaaggaagt
    29341 gatctgaagg agatcaaaca aatcttccaa agaggacaac aaaaaggctc aatcatttat
    29401 caagatgtta tctctcacga caattcgtat cttgaaaaaa tgggcttgta cgatcccaaa
    29461 acagatacct tagatgaaga aggtttgaaa gcagctggaa gaaaaatgat ggagacatta
    29521 ttcgagaaag aacaattgaa tgaaacaggt tactggatgg caacgattca ccgtaacact
    29581 aagcatatcc atattcattt tgcagttgtt gaaaaagaaa atacgcgtaa accgtatact
    29641 gagattgaaa atggtgtgag ttatatcgta ccgaagggga agagaagaca agcaacatta
    29701 gacgcaatga aaaccaatta tgtacatgag ttagaacgtt tctcttatga aaaggatcga
    29761 atgatcggta tggagaaacg aaatttattg acacgaaaaa gtgatttgcg taacacctta
    29821 acaaaagtag taaaagaacc agcacgttac gatcgacacg ccatgaactt attaaatgaa
    29881 gtatataaaa ccctacctga aaaacgttcg gaatggaatt atggagatga aaatcgaacc
    29941 aagctttcac catttacaag gggaaaactt gatgagttaa ccaaatatgt tttaacaaaa
    30001 gaacctggat atcaagaata tatacagatt tcaaaagcat tgaaagaaga agccaaaagc
    30061 ctttatgggg aaagcaaaag agaaacaaag aatgcagaaa aaaacgccct ctttgattta
    30121 aaaaagcgca caggaaatgc gattttaaca gaactgaaga gacaggatag tcaaataaaa
    30181 ccattaatag aaagtgtcaa tcagatgcaa tctatttaca atgaacgatc ctttcgaaca
    30241 ctcaaacagt tgccaacaaa tgaatacaag tatagttatc aagaattcgt aaagcgtagg
    30301 aaacaattcc aacaaagagt tgtcacgcag cgaagcttgc gtcaattaaa tcgaacaatt
    30361 aatgcacatg aagaaaaata ccacgcaagt aaagcatatg aagagcaaca gcgaagaatc
    30421 caaatggaac aagaaagaca ataggaggaa gagaaatgaa acaatattta gatcaatgga
    30481 aagtcataga aggatcacta aaagaagaac gaatcgaaca acttcctgat tgtttagaaa
    30541 aagagcattt gtttcagata agcgaaatgt tgagaaacga acagtttgat ccaaatcaat
    30601 ttttagttgt tgagtaccca gctactggtg tgtattgttg taatcatgtg aagggtgaaa
    30661 aatattttat tattcaagaa tacgaaggta agttagcgcc ttattatact acttgggaaa
    30721 taaatgaaga gggaatcaat aatttcccat gtgaaagcat tgaagagtct atttctctca
    30781 cggaatgtta aataaataga gacgtaaaag agtcctgaac gtgattgtcc aggactcttt
    30841 ttcaatgaat tgttttccgc caattcactg agtggtgcga ttcaatttta ttatatcaaa
    30901 agaaagtgag attccaaagt gaagggagga agaagaaatg actcagacaa cgattggtgt
    30961 tgtggttgaa aaaagcaggg ataatctcgt ttttgtgaca gaaattcaaa caggtagagc
    31021 ttttgtagtc acagacaaag ctgcaaaagc gtatcaaaat ggcaatattt taacgttaaa
    31081 tctgactacg aagatgttcg ttgatgcagt agaaaattat ccatttgttt agacaaacga
    31141 tattttacaa ggaggaaacg gacatggcag aagaaaaaga accactagat aatagtcggt
    31201 tgggaaagtc caaaagaaaa ttagtacggt tgcaaaacga attaaataat caatttcaaa
    31261 agctatttga tcaccaaaaa ttgacaaatg ggcaaccaat gaatgacaaa cgaaatggtc
    31321 gttcatggtt taaccagcaa gaaaaaatag aaaataaaat acaaagtttg agagaagaga
    31381 tcaagcaaca agaaaaacag gtagaaaaac ttgaaagaca agaagagcta aaggaaatgg
    31441 gctataacaa gtacggcgga ctggatatga cgatcgataa tattccaaga atcaaagaag
    31501 aaatcgaacg ctttgaaaaa ggtgaatcga ctttttcagc cgccacgatc cgaaaatatc
    31561 aacggaagtt ggaaacatta gaacagctga aagaaaaatc agaaaaagga aaagaaaata
    31621 tcctccctga agtacaagcg atcattgaca gcggacgagt gacgcaatgg aaaaaaaatc
    31681 caaccattta ttttttgaaa ggctatcgaa aagttgcttt agaactgaat gaaaacgggg
    31741 gatttgagga atcaaaaaaa taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg
    31801 aattacttga agaggctgca ccaactgatt ctctgaagga gaaagaaaaa gatcatttct
    31861 atcgagtaga attcaacgaa aatgatccag aaaaaggatt gaaaagttat ggtggggaga
    31921 tcgtaacatt agaattgatc gatcaactta aaacgttgga taaccaatac gctgcagaag
    31981 caggttatta taaattctat tttgaagaag tgaagaacgg agaagtagta gatcagatcc
    32041 gaatggatct aggggatggc gtcaacagta atcaccccat ctatttagag ttagcaaaat
    32101 tgtgcgaaca agtacctgag aaggaacaaa aacaatcggt caaaaatgaa cctgtttcga
    32161 aagaacaaat gcagtcgaaa gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg
    32221 cagaagagat caaacaagaa gttaaatccc tttcgcaaca ggcactggat gcggtgaaaa
    32281 agcataccca ttcttctgaa gacgtcaaag aacttttgaa ctttatgtct cgttttccag
    32341 aacgatcctt tagaaatcaa ttattgattg aggaacaatt tccaggtgca acggcttgtt
    32401 taggtcgtgc cgcgttgaaa aaagaaggaa tctatatcaa aaaaggggaa caagggaaca
    32461 agatctttgt cagaaaaacg gtcaaaggat tttatgagaa aggacgtggc tttgttcgag
    32521 aaacagaagc tacaccagaa gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca
    32581 aaaaacctta ctacacgatt gaaaaagtgt ttgatatcac acaaacacag ttaaaacctg
    32641 aagactatcc gaaaatcttt ccgaaccgtg tctttgattt tcaattggat aaaaaaggac
    32701 agtcagaact tcaagctggg attcaagcgg tagccaacaa tattggaata caaattcgag
    32761 atatgacaga aagtgaagtc tatcaaagag aattaggaca agcacgtggg gcgtatgttc
    32821 gtaacgaatt tactggcgaa gaagaaatcg tcatgaatac tcgaaatact cctacgcagc
    32881 atttagctac aagtattcat gaattagccc atgcaagaat gcacaaattt tcagaattag
    32941 ataccgcaac taaagaattg caggcagaaa tgacttctta tattgtgtgc aaacattttg
    33001 gaatggacac gtcggagaaa gctattcctt atattgcagc atggacgaag aatggtcaga
    33061 cgttggatga taaggaagcg gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg
    33121 caaatgaatt cattcaaacc atttctaatg aaatcaatca atacagagaa agagaaccag
    33181 agatccaacc agcagaagtg aagcaggagc ataaaaatac tgtagaaacg gcagagaata
    33241 agaatattgt gcccgttggt tcactttgga tcgacaagaa agacgggaaa gtaatggaag
    33301 aagatacggg tcgaacgtta catttgaagg atgcggcgtt tattgaagat ccgcagcata
    33361 atcaagtgat tttaaaagga aaaagttatg gaaaagagat tcaaacggcg ttaccttcag
    33421 aagaatttgc gctaggaaat ccattccgat tttcacttga aacagtgtca gaagtggcca
    33481 aacgaaaaaa tgaaatctat tatgaacaac aattgtcaca aaaagaacgc gtataaaaca
    33541 agtaaaaaag actatctgaa aaacggatag tcttttttct tttgggaggt ttgaaaatga
    33601 ccgaaaaaaa aatgagtctt attgatcgat gtaaacagat cgatatagtg gattttgctc
    33661 gaaacaatgg aatggctgta gtcaataaag gacgagacta tcgcttagaa gaccatgatt
    33721 catttgtttt tgatcgaaga aaacaacgtt tttattggaa cagtcaaaat attagtggcg
    33781 acattattga attagctaaa ctttttttca tagacaaaga gatccaagac tctaagcaac
    33841 aatttaaagc agccactgat tttattctaa agaatgaaga caaaacagaa cgagtggaaa
    33901 atcttcattt tgaaacagaa aagtacaaag atcaccccgt tgattatcaa ccactcacag
    33961 aaaaaggaag gaattatctg aaggaagaac gaaaactacc agagtggctg attgattatg
    34021 cagaaaaaga agggttgatt gccgaactaa agccaaaata tgaacggcaa aatttcttag
    34081 ttcgagacga tcgtttagat catgcggtcg cctttttatg gaaagatcca cagacaaaag
    34141 agacagtagg ggcgagttat caaggaacgt tcattgatta tgaacgtttt ggtgagagag
    34201 gcacatataa gcatatagat aaaaattcga cagcgaatca tggctttaac ctaaagatcg
    34261 gtgaccctaa gcagttaaaa ttttttgaga gtagtattga tttacttagc tatgctgcac
    34321 tgaatcgtga tcagttaaac gatacgtggt tagtctctat ggaagggtta aaacaccatg
    34381 tgatcagtca ttattttggt gaggcagtat ctgaattgag aaagaaacaa gcctttcctc
    34441 aatccatcga gatttgtgtg gataatgacc gtgcaggaca tattttctac gaaaaagaac
    34501 aattaatggg cgcagtcgat ccatttacga atcagaaagt acgttgtgaa cgaggaatcg
    34561 ctaatgattg gcaagtgcca aaagaataca aaatcattta tgaagaagtc gcaaaagaag
    34621 aaaaggtcac accagaagct attatggcca tacacaagac agaaaacaat ctgcaattaa
    34681 cgaaccaact ggtttccgct cacaaagtaa atgcgttttt tggccagcag ctttctgtta
    34741 acgattcaat agaagccatt aatttgaaag atatttgtag agaagtcgca aaagaattaa
    34801 aagtttgtga acgcgtggat ggtacgtacg attttgatcg tttttatcaa gaaaaagggg
    34861 atattaatgc gcagattctt ttctcttata aagcagaaca atactacaaa ggctataaaa
    34921 atcatgaaca tgaatttata cctgaagtaa aaaaggactg gaacgatcaa ttgaagcatg
    34981 agatccagca acaagaaatc agaaagcaaa aacgtgccat gttgtttcaa caaggcagac
    35041 aacaagaaag ggagtgaaat cgtcatgatg aaaaccgtta ttttagcaga aaagccgtca
    35101 caagcgaaag cttatgccga tagcttctct aaagccactc gaaaagacgg gtattttgaa
    35161 atccaagatc gattgtttcc tggtgaaact gtgatcacgt atggttttgg tcatttagtc
    35221 gaattagatt cgcccgatat gtacgatgaa aattggaaac aatggtcatt agaacatttg
    35281 cctattttcc ctacacatta tcactatcat gttcctaaag ataagaaaaa gcaattcaag
    35341 gtggtgaaac agcaacttca atcggccgac accattatta ttgcgacaga tagcgatcgt
    35401 gaaggggaac tgatcgcttg gacgatcatt caacaagtag gcgccgatca aggaaaaacc
    35461 tttaaaagac tttggatcaa ctccttagaa aaagaagcca tttatcaggg attccagcag
    35521 ttacgagacg caaaagagac ctatccaaaa tttgaagaag cacaagcacg tcagatcgcc
    35581 gattggttaa ttgggatgaa cggtagccca ctgtatagtt tactcttgca gcaaaaaggc
    35641 ataccaggaa gcttttcctt aggcagagtc caaaccccaa cgctttacat gatttatcaa
    35701 ttgcaggaaa agattagaaa tttcaagaaa gaaccttatt ttgaaggaaa atccgaagta
    35761 atcgctcaaa atggcgcatt tgatgcgaag cttgatccga atgaaaccca agcgacgcaa
    35821 gaagcatttg aagattattt aaaagaaaag ggggttcaat tgggaaaaca gccaggcatg
    35881 attcgccaag ttgaaaccga gaaaaaaagc gcggcaagtc cacgtctttt ttctctatcc
    35941 agccttcagt ctaaaatgaa tcagctcatg aaagctagtg ccaaagacac tttggaagcc
    36001 atgcaaggct tgtatgaagg gaaatatcta agctatccac gaacagacac cccttatatt
    36061 acggaagggg agtatgcgta tttgttggat catttagatg aatacaagca ttttttaaag
    36121 gccgaatcaa tcccaacccc tattcatacg ccgaatagtc ggtatgtgaa taacaagaaa
    36181 gtccaggaac attacgcgat cattcctaca aaaacggtta tgacagcagc ggcttttgaa
    36241 caactaagtc cactgcagca ggccatttat gaacaagtgt taaaaacaac ggtggccatg
    36301 tttgcggaaa aatataccta tgaagaaaca acgatcttga cgcaagtcca gcagcttcag
    36361 ttaaaggcaa tcggaaaagt accgatagat ctaggttgga agaagttatt tggcaaagag
    36421 aacgacggaa aagagaagga agaagagccg ctacttccta aagtgacaaa aggagaaatg
    36481 gtgacggtag atctacaagt ccttgaaaaa gaaaccaagc caccacagcc ttataccgaa
    36541 ggtacgttga tcacggcgat gaaaacagct gggaaaaccg ttgatagtga agaagcgcaa
    36601 tccatattga aagaagtgga aggaatcggt acagaagcga cacgggcgaa tattattgaa
    36661 accttgaaac aaaaggaata tatcaaggta gagaaaaata agctcgtggt gacgaataaa
    36721 gggattttgc tttgccaagc cgtggaaaaa gagccgctgc ttacgagtgc cgaaatgacc
    36781 gccaaatggg aaagctactt gttaaagatc ggtgaacgaa aaggaacaca aaccactttt
    36841 ctagccaata tccaaaaatt tgtctctcac ttattggaag tcgtaccagg gcaaatccaa
    36901 tccactgatt ttggatcgac gttacaagaa gtgaaagcag ccagtgaaaa gcaagaagcc
    36961 gcgcgtcatt taggaatttg tccaaaatgc caggaacaag aagtcttact ctatcaaaag
    37021 gtggcagcat gtacgtctga agcctgtgat ttcaaactat ggacaacgat tgccaaaaag
    37081 aaacttacag cgacacagct gaaagagatc attcaaaata gccgaacaag ccaaccagtg
    37141 aaagggttaa aaggtcagaa gggttcgttt gaagcaacga ttgttttaaa agaagacttc
    37201 actacaggct ttgaattttc tgaaaagaaa aaaacgaact tcaagaaaag aacacgacgc
    37261 actacaaaat aatggagggt taatcttatg cgtaatacaa cacacaaaca acaagaaatc
    37321 gaaaatcaaa aagccaaaat tcgttcagaa caggaaaaaa tgcgtgccag caaacgaaga
    37381 ctgcagcaat tgaagaacca gcagcggatt caaaaagaaa tcgaattaga tcgataaatt
    37441 cctttcttgt taatataaaa ctaacatgtt atagttgtgt tagttttata ttaactttag
    37501 gggaagagta atgaaagaca aaatccaatg tatttttgat aaacataatg gcaacctatc
    37561 cttgaaggat gctagaagtg aaggattatc gcctatgacg ttagatcgat tagccgaaaa
    37621 ggataaaata gaaaaggtag caccaggttt ctatacctta aaggatgcgt tcgtggatga
    37681 attgtatctc gctcagagta tctattccag agggattttt tctcatgaga ctgcgctcga
    37741 tctttttcaa gtaggaacat atatccctaa aaagatcaat atgatgtttc ctaaaggata
    37801 caatgtatca aaggagaaat tagatcagta tgccattcaa ccgcattaca ctaataaaga
    37861 aaattttgac ctgggagtca cagaaacaga aagcttttac ggcaataaaa ttttagtcta
    37921 tgatttagag cgaacgttat gtgacatgtg gaatccaaga tacaaagcaa gcgtagaggt
    37981 aaaacaagaa gcattaaaag aatatatgac aagtaccagt agaaatacaa ataagctaag
    38041 aagatacatg gatattttaa aatcaccaaa agaaatgact ttgtatatgt tgccacttta
    38101 ttgagaggag taaagatgaa tgacaccgac acaatttaaa gagaaaacaa gaaatttcgc
    38161 agcagagaaa catttaaacc cacaaattgt ccaaagatat tatatgatgg aaaaattatt
    38221 agaatgtatt gttgaatcgc cttatcatga tgattttgta ttaaaagggg gatttctgat
    38281 tggatcaaaa tacgggttag aaaaccgttc aaccgttgat attgatacga cttatcgaaa
    38341 ttcgaaacta acaaaagaaa agttagaaac tgttttttct gaattaacag ctaatcctac
    38401 aaaagatgga attcgttttg aattaaaggg attaacagag acgagggaag ccgattatta
    38461 tccaggtttt caagcaaagt ttattgctta tcttgaaaat gcacgtgtac cttttaaatt
    38521 agatattact tcaggtgatt ctattattcc agcagcattg atgtatgaac acaaattaat
    38581 gtttgaagat aaaacgattc atattccagc ttatcctacg gaacaaattc tagctgaaaa
    38641 attacatgcc acgtttagtt ttggaaaaga taattcgcgc atgaaagatt tttatgacct
    38701 gtatatgatt ccgaaattag aacgtatcga tgagaaaaat ttgtataaga gtgttcaagg
    38761 aacattcaag gaaagaaata atcaatcggt gtttaagcat ttgtatgatc aggaaatgcc
    38821 tcaattggtg aaagatgagg gcttgagaga aaagtggaaa agataccaac aagaaaacta
    38881 ttttgccaaa gacatttctt tcgaatctac actaacttcc gttgattccc tgatgcaatc
    38941 aattgtagag caagagaagg cagaacgaaa acaaaatttt aagagatcac aacaaatgaa
    39001 tcaagaaatg gagagataaa gatgatcaat aatgtaactt tagtagggcg attaactaaa
    39061 gatccagatt tacgttatac cgcaagtggc acagcagtgg cgactttttc cctagccgtt
    39121 aatcgtaatt tcacgaatca aaacggcaat cgagaagctg attttatcaa ttgcgtgatt
    39181 tggcgcaaac cagcagaaac gatggcgaca ttagctaaaa aaggcagctt gatcggcgtt
    39241 gtcggacgaa ttcaaacacg gacttatgac aaccagcaag gacaacgtgt gtatgtgaca
    39301 gaagttgtgg ccgataactt ccaactatta gaaagtaaag cagcgacaga aagccgtatg
    39361 cacgctgatc aatcgtccag cagtccaagc cctaccacct ttgaacaacg ggatacagcg
    39421 acgcctaaca acaatggatt gaacgcttca cagaatccat ttggtggaca atcaatcgat
    39481 attagcgatg atgatctacc gttctaagta gcattttcta ttggttgcat ttgctacggt
    39541 ttatgttata atttagacaa caaaaagaat tttcaatcta taaccaaaaa ccactagctg
    39601 gcgggctagt ggctttcttt tacgtttcta ttataagaat taacgggtag gcttactgtc
    39661 tttcttggca aatttacaat caagccattt gcagatatag tgcgcggcta cttctgccat
    39721 gattgcaaaa acaaaatcaa aaagaatttt caaacctata acctcctccc cttgccagat
    39781 taggccgggg tagcagacag caagactatt atagcataat tgaaatatcc aaatgattgg
    39841 atttttgcta taattttagc gaggtgattg tgatgaacaa atatgttggt ttgcttgata
    39901 aaatccgagt aataaaaacg caaccgttat tggttcgctt tactttacaa acgattcatg
    39961 aatcgattaa ttgtgtagtt gcagatattg aaattatcga taaattgcta attatggatg
    40021 atggaaaata caatattgcc gtcacaggtc acttcaataa acgaaatcag ctagttattg
    40081 ctagcatgta tgttagaaat cccgatcatt ttacgcgatc gatgggcata taaataaaag
    40141 aagagttgta gtcctaaatg aggattgcag ctctttttgt tttacataga aacaggaaaa
    40201 gaccttttta ggaagacaca agtgccttct caattgaaaa acctttctct cactccaacc
    40261 gccaccgccg ttcgagaaga aaggaagtga acgctgcacg ttcactaaga tatggtgtct
    40321 tgcaaagcaa gacaaaatag acaaaacttc ctctcaccaa aaggttcgtt cctgttcgtt
    40381 atctctttat tgatttgcca gaccggcaac aagttgcctt ttatcaccaa aaagcgacaa
    40441 ggacaagggt aaatggcacg ctgcgcgccc ttgtccttgt cgcttttcgt tgatttattc
    40501 tggccaacaa atcaataaag aaagaactaa cgaaaggaag taaaaccttt cctaagagga
    40561 ggcagaatca aacatgcgaa agaaatttga ttattggggt gttcccttca gcgaattatt
    40621 cccaaactat catgcaccac atactgttga atgcgattgt ggagaaagag cgaaatgtat
    40681 caaaagctat cgtttgtatc aatgtccaac atgcgggaaa aaatatacct tgtcttatgg
    40741 cgattacatt ttgattgatg agaaaggaaa gaaacgctga tgaaaacaca acacaaatta
    40801 ttgactgtaa aagaagtcgt tcaaattttg gtggacaaag aagtcatttc tgaaaaagta
    40861 gcagaagctt tacttattcc gcggtactgg acgatagaaa cccctttagt agaggatgca
    40921 ccgactatgc tatttgaaga cctagtgaag attgcaggat atgaactgca ttatcaagaa
    40981 aacatggaaa cttatgaaat cgaatattgg ttaaccaaat tagagaacta aaaaggagaa
    41041 aaaatatggc tcaaaattac tatgacgaat ttgtcaaatt acctttggat aaaatggcac
    41101 aaaaaatgga ggatatgacg ttcctatacc atgaaacacg tgtacccaaa aaacattaca
    41161 aggaaaaatt gtcagtcgca gtggaagaaa tgattgaatc aggtgtcgaa atgaatctca
    41221 ttgcgacgta ctatcgaaca ctggaagaac tgaaaaaaca aaatggaaaa tggtttttcc
    41281 aagccttact atgcttggaa gtaggtgtca aaccaagcac tatcaaacct tccgaatatc
    41341 aagccttaga actgacttat gcaaaattcg cacagattaa gaaagctaaa gcaatggcta
    41401 gcgactggct agatactttt gaaagtatcg aaaaaaatgg tgcattttat acgattgaat
    41461 cggaggagaa agataatgaa taaggtggtt tatcagctaa caacagaaga tgtttcgcaa
    41521 tttttaacaa gcaaagaaca cttgaatgaa gtaatcagac ggattcaaaa agactttagt
    41581 tgtatggaag aaatgaagta ctttattcaa agagtggaag aacagttgta tatggaaagc
    41641 gaaacaagtc aaacgaaggt cacagtcagc cataatcatt tagacgtgta taaacgtcgt
    41701 cctgaaacgg taaaaaaagg aacagagctt ctacgactag aaacagaaaa atacatcatg
    41761 aatgtgtacc tagaaaggag tgagctggtc gaaaactttg tcagctacac gatttgtagg
    41821 aaacactatt actcagaatc agaatattat tcaattttcg agagcatgga attaatggaa
    41881 gaagaaatgg aagagctaaa cagcaaaaat gcgacggtag acgattatta ccttgtattt
    41941 actaggtttt tgacgtgtgg gacggaatct atcgtgttaa tgggaatgga ttatgaactc
    42001 gctgtacccg aagcattttt gagggaatat gtagaagaag tagataaccc aggcgacgac
    42061 tggtacacga ctttaactga ttttttagac acctacactt acgacgatac agaagaaatc
    42121 caaaatgaac ttgaccgtaa acgaatgcca tatcaacgat ttgaaaggaa aaaaggtaaa
    42181 taaccattta taccgaaaag tgaggatgtg tgaaataaga acaaaaaacc ttgaaattaa
    42241 gggaatggtt cttatttcgc accaatcgct ccaaccgccc ccgccgctta ggtggtgcga
    42301 aataagcggg caaagcccga taacctaaga gaaagaagga gatccatatg aataaaatca
    42361 ttcctctatt gttcgtactg tttgttggcg agatacttat gcgtcatgct gcagctgtac
    42421 atttaaactt cgtagtattc ttaggaatac tggtattttg tttgatcttt tggcgatttg
    42481 tattagccct tgtgagtcta ctattcaaga tgattgcagc catatttttc atagggttat
    42541 ttcgatgaaa ggagagagta ctaatgccaa ttgcaatagg aaataaacgg ttacccgtga
    42601 cattagatga aaagagacaa aaagaattgc agcaactaaa gcagaagtac ggaaaaagtg
    42661 aatctaagat tatgtgtatt gcgttagatc tattgatcgc gcaagaaaaa gcaggatttg
    42721 atataccagc actaaaaaag tgacgtcact tttcatttga agaaacaaaa gtgatagcac
    42781 ttaattgttc ctactattta gaatattttc tatgtccttt ttattccatt ttgtatcaat
    42841 aactatgaaa tctttaaagt atccagaaga gattattttt agatcaattt ttttcttacc
    42901 tgattctaaa gattttgttt tcttaaacat attatgattt cctttcgact attttcatat
    42961 aaatgttaac atagtttatg gattcatgga atgttaatct aatttaatag aaaaggataa
    43021 ttaagtatat acgttttttc ttatgtatgt tatactatgt atatacagaa agaggtgtct
    43081 actatggaaa tgttacctat aaaaaaatgg ggaaatagta atggccttag attgccaaag
    43141 tatattatgg aatatcttgg aattcataca gaagacaaag tgaagataat acaagaagaa
    43201 gtaaacggtc agaagcggct aattatcgaa gcggctaata tagaaaatga attaacaatt
    43261 gaacagttat ttgaaaatta cactgatgaa agaaatcatg tgacgattca aaatttaggt
    43321 gaagcagtag gtaatgaaaa atggtgagaa aacctagaca aggcgatatt ctattattga
    43381 atacagcacc tcgatctgga cacgaacaga caggtaaaag accttatatt gttttaagtc
    43441 atgatattat tgcggattat agtaacgttg ttacagttgc tccaatttct agtacaacta
    43501 gaaactatcc gctatatgta aatataaact cagaatatga aatgaagaca acaggaaaag
    43561 tattattaga tcaactaacg acaattgatt atgaagccag agagtgtatt tttttggaaa
    43621 aagcgcatga tagtttagtt gaggagttat tgatgaaagt tagaacagtt tttcaaaaag
    43681 taagcaaata aaatagaaac agcagcatga tcaactattc gtgattgacc atgctgtctt
    43741 tttttattct atatacggtt tgtctcgtaa cattgtagtc ttttgcaatc ttagcgatcg
    43801 caacaccttt ttttagatcc tcaacgatgt ttttataaac aagacgacgt tggggatctt
    43861 ttgcattggc actgtatagc ttaggacgtc ctttataaac accgttcgct tttgcaatct
    43921 taatgccttg tgcctgacgt cgtttagatt cggtacgttc ttgttcagcg atcatggcca
    43981 aaatttgaat gatcaaatct ttaatgaatt tatccaggag aggattgcca attgcttcgg
    44041 ccatgatcgg tagacttgtg atgatcagct gcacattttt cttcttcaag taattgactg
    44101 aagcgatgat ctcgtcgtaa tttcttccaa gtcgatcaat agcttccaca ataaaaatat
    44161 cttgatctcg gacgaaatcc agtgcttctt gaaaaacaag tcgatgagta atcgttgcgc
    44221 cagattgttt ctcaatgaaa attctctctg caccgaattt tttcatttct tcaatctgcc
    44281 gttgttcatt ttgatcgatg gatgagacac gtatgtatgc aactctcaaa atttttacct
    44341 actttctgca actatttaaa aaacacccta atcatacacg agaaaaccag atttttcaat
    44401 gtcgcggtcg tgtctagtta gggtatacct tatatagaca aaaactaatg atggaggaaa
    44461 tagtatgtgt cacttttctt tttaaatggc aatatttttt gtaaataaat gtcaatcaag
    44521 aaaatttaaa cgattatgac atta
//
LOCUS       DAFLWQ010000014        42896 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.015, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000014 DAFLWQ010000000
VERSION     DAFLWQ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42896
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.015"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            35..3313
                     /locus_tag="L1V16_000778"
     CDS             35..3313
                     /locus_tag="L1V16_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HBN1275139.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(3854..5761)
                     /locus_tag="L1V16_000779"
     CDS             complement(3854..5761)
                     /locus_tag="L1V16_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HBN1275140.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            5891..6766
                     /locus_tag="L1V16_000780"
     CDS             5891..6766
                     /locus_tag="L1V16_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HBN1275141.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            6846..7820
                     /locus_tag="L1V16_000781"
     CDS             6846..7820
                     /locus_tag="L1V16_000781"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBN1275142.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            8000..9145
                     /locus_tag="L1V16_000782"
     CDS             8000..9145
                     /locus_tag="L1V16_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBN1275143.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            9282..9626
                     /locus_tag="L1V16_000783"
     CDS             9282..9626
                     /locus_tag="L1V16_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HBN1275144.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            9897..11183
                     /gene="efmA"
                     /locus_tag="L1V16_000784"
     CDS             9897..11183
                     /gene="efmA"
                     /locus_tag="L1V16_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HBN1275145.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(11321..11920)
                     /locus_tag="L1V16_000785"
     CDS             complement(11321..11920)
                     /locus_tag="L1V16_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HBN1275146.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            12324..13445
                     /gene="mnmA"
                     /locus_tag="L1V16_000786"
     CDS             12324..13445
                     /gene="mnmA"
                     /locus_tag="L1V16_000786"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBN1275147.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            13691..15112
                     /gene="arcD"
                     /locus_tag="L1V16_000787"
     CDS             13691..15112
                     /gene="arcD"
                     /locus_tag="L1V16_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HBN1275148.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            15126..16244
                     /locus_tag="L1V16_000788"
     CDS             15126..16244
                     /locus_tag="L1V16_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HBN1275149.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(16304..17596)
                     /locus_tag="L1V16_000789"
     CDS             complement(16304..17596)
                     /locus_tag="L1V16_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBN1275150.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            17728..18306
                     /locus_tag="L1V16_000790"
     CDS             17728..18306
                     /locus_tag="L1V16_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1275151.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            18435..18812
                     /locus_tag="L1V16_000791"
     CDS             18435..18812
                     /locus_tag="L1V16_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HBN1275152.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            18745..20817
                     /locus_tag="L1V16_000792"
     CDS             18745..20817
                     /locus_tag="L1V16_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBN1275153.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(21028..21975)
                     /locus_tag="L1V16_000793"
     CDS             complement(21028..21975)
                     /locus_tag="L1V16_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1275154.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            22221..22685
                     /locus_tag="L1V16_000794"
     CDS             22221..22685
                     /locus_tag="L1V16_000794"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBN1275155.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            complement(22747..23790)
                     /locus_tag="L1V16_000795"
     CDS             complement(22747..23790)
                     /locus_tag="L1V16_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBN1275156.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(24167..25132)
                     /locus_tag="L1V16_000796"
     CDS             complement(24167..25132)
                     /locus_tag="L1V16_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBN1275157.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            25366..26211
                     /locus_tag="L1V16_000797"
     CDS             25366..26211
                     /locus_tag="L1V16_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1275158.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            26402..27589
                     /locus_tag="L1V16_000798"
     CDS             26402..27589
                     /locus_tag="L1V16_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBN1275159.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            27595..27951
                     /locus_tag="L1V16_000799"
     CDS             27595..27951
                     /locus_tag="L1V16_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBN1275160.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            27953..28291
                     /locus_tag="L1V16_000800"
     CDS             27953..28291
                     /locus_tag="L1V16_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HBN1275161.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    28367..28623
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            28686..29720
                     /locus_tag="L1V16_000801"
     CDS             28686..29720
                     /locus_tag="L1V16_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1275162.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            29713..30399
                     /locus_tag="L1V16_000802"
     CDS             29713..30399
                     /locus_tag="L1V16_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1275163.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            30423..31271
                     /locus_tag="L1V16_000803"
     CDS             30423..31271
                     /locus_tag="L1V16_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBN1275164.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            31468..32241
                     /gene="sufC"
                     /locus_tag="L1V16_000804"
     CDS             31468..32241
                     /gene="sufC"
                     /locus_tag="L1V16_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBN1275165.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            32254..33540
                     /gene="sufD"
                     /locus_tag="L1V16_000805"
     CDS             32254..33540
                     /gene="sufD"
                     /locus_tag="L1V16_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBN1275166.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            33537..34772
                     /locus_tag="L1V16_000806"
     CDS             33537..34772
                     /locus_tag="L1V16_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBN1275167.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            34759..35229
                     /locus_tag="L1V16_000807"
     CDS             34759..35229
                     /locus_tag="L1V16_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HBN1275168.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            35234..36625
                     /gene="sufB"
                     /locus_tag="L1V16_000808"
     CDS             35234..36625
                     /gene="sufB"
                     /locus_tag="L1V16_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBN1275169.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(36720..37862)
                     /locus_tag="L1V16_000809"
     CDS             complement(36720..37862)
                     /locus_tag="L1V16_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1275170.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(37901..38635)
                     /locus_tag="L1V16_000810"
     CDS             complement(37901..38635)
                     /locus_tag="L1V16_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1275171.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            38867..39142
                     /locus_tag="L1V16_000811"
     CDS             38867..39142
                     /locus_tag="L1V16_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1275172.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            39240..41237
                     /locus_tag="L1V16_000812"
     CDS             39240..41237
                     /locus_tag="L1V16_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275173.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSFYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELTNTVC
                     ERLRNVGNNSVENALKENRGYFVKQGFTLERASKDIKRLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(41313..41648)
                     /locus_tag="L1V16_000813"
     CDS             complement(41313..41648)
                     /locus_tag="L1V16_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1275174.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            41776..41990
                     /locus_tag="L1V16_000814"
                     /pseudo
     CDS             41776..41990
                     /locus_tag="L1V16_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            42027..42389
                     /locus_tag="L1V16_000815"
     CDS             42027..42389
                     /locus_tag="L1V16_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HBN1275175.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADAVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVALAFIPVVFGAVAVIMGYLYRDKDEQMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            42435..42761
                     /locus_tag="L1V16_000816"
     CDS             42435..42761
                     /locus_tag="L1V16_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275176.1"
                     /translation="MNKVNMNKKFIIIVIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
BASE COUNT        14053 a         7676 c         9006 g        12161 t
ORIGIN      
        1 aaacgctttc taatttgtta cgggaggaat acacttgtta aaaaaacgta taaaatacag
       61 tgcgctaatg atgaatctcc ttatgctcag taccccggtt ttaatttctg tcgttgaagt
      121 tgctgctaac gaacaacagt ctgtgaacga agaaaatgca cacgtgaaca ttgaagggat
      181 gtcaacaatg gaggaaatac caagaactag tgaagatatg gatacggaag aaggaaatga
      241 tcctatgatg aaagaatcag aaaatgaaaa gacaaaaaag caatctgaag aagcaaatga
      301 agagtggaaa ggggttgttt tcggagaaag cacaagtgct agtaggtatg ccattgaacc
      361 attagaagac ggcgtgcggc tctcttccac gaataacggc ggaaaattcc agtcaagcgg
      421 atcagatgga atgacctatt attatcaagc aatccccaaa gacatcaact ttaggatgcg
      481 ggcgacgatc gaaatagaat cttggaccta tacgaatgcc caagaaggat ttgctttaat
      541 ggtaagagac gcagtaccaa aaaatcattt gtttgggcag gcattttatt caaattcatt
      601 tgccatacta ggcagtcgga tcgaatatgt ctgggactcg gatagacaag aagtggtcaa
      661 cacgagcggc agcaaatata cgatgcgact tggattgggg acacgggcaa tcacaggaat
      721 atcatctgaa gatccgcaag ctgcgccagc tcctgggagt gtctcagtgg aaacaacacc
      781 tttagagact tcagcagggt tcttggaaaa agaaacaggt tcttataata tattcggaaa
      841 cggtcatggg aatctgtttc cggccacgaa ctcgattact aaactggacg tagagatgaa
      901 aaaaacgaat actggtttag aggcatatta ttacgatcct gaaacaggag aagaaatggc
      961 ttctgacatc atgtatgact gggaaaaatt atacgcttca gatgaatcgg ttatttatgc
     1021 aggatttgct gcagcaagga atatgacgat caaggtagaa ggaatcgaag ttgcttactc
     1081 agatcctgcg acagatcctc ctgggcaaga aagacctact cgcttgattg atccgattta
     1141 cactgtgacc tctagtaatc attcaggaaa ccaagatcat actatgtcct ttagagcaaa
     1201 tgctgacgga ttattgacaa ttaaaaataa agcaacagga gaggtgctta agaacgcaaa
     1261 aaacttggct atcactgcga atcgggaatt tgattatcag acaaaactga tggaaggaac
     1321 gaacgaattt actttcagtt ttacgccaga taaaaactat ccgccagaag aatacgtaga
     1381 gatgactagt tatgaaacaa aagagattct tcatacagtg gactaccgta aacctaaata
     1441 ttcgacagtt tatgtaacac cagaagggtc agatgcagga aacggaagca gacaaaatcc
     1501 attatctctg acacaagcat tgagatacgc atatgctggg cagacaatcg tcatggcgcc
     1561 tggaacttat tccttcgaaa gaggattgac gattccaaaa ggcgttaacg ggacaagaga
     1621 aaacccgatt cagttgattg cagagaaaaa tccagaaaac aagcgtcctg tacttgattt
     1681 taaaggaact ggaaatggga tgacactgtt cagtcactac tggggtttac gagggtttga
     1741 cattacaaat agtgcagcta tgcaaaaagg attacagatt tctggaaatc ataatttgat
     1801 cgaagagatt catgcttatc ggaatggaaa tacaggaatc caaatcagcg gtagctcaaa
     1861 tgatcctttc gaagcatggc ccgcgcataa cttagtcaag aactgtacat cttttgaaaa
     1921 tgccgatcca ggatttgaag atgccgatgg atttgcggcc aaactgacaa taggagaagg
     1981 aaatgtattt gacggttgta tcgcgtatca taatgcagat gacggttggg acctttttgc
     2041 taaaaatgaa acaggttcga tcggaaaagt aatcatcaaa aactcagttg cttatcgaaa
     2101 cggctgggta ccaggaattg agggagaagg taacggtaat ggattcaaaa tgggcggttc
     2161 ttctttaacg ggccctcatg aattgatcaa tagtttgtct ttcgaaaatc ttgcgaaagg
     2221 aatcgattcc aatagcggaa cagatattat cgtcaatagc agtacaagtt ttaataacgg
     2281 ttcatataat gtggctcttt atacctcttc agcaggaaac acagactacc atgcttctgg
     2341 tatcttatct ttccgaacag agaatcttga gatgagagag cagatccgcc cattgaatca
     2401 aaacgaagat caaatctacc actcgttgaa ctactattgg aatgaacgag agaaacaatc
     2461 agaaaatact cttggacata ccatatcaaa agattggatc gagtctctaa atacatgttc
     2521 gaaagaaggt cagcagcctg ttacgcgcta tgaaaatgga agtatccatg ttcatggact
     2581 gatgcagatt aaaccgggga atcgtcaaac agaaaaggaa agagtggatg gtcttccatt
     2641 atctgtaggt gctatttttg acggagaaac ctcaccgtct tcggaatatc cagagtatgc
     2701 aatcgtacaa gaaccaaatc agacaaaacc aaatgaacaa aataatccga ttattataca
     2761 agaagcaaat ggtgtggcgg agaatgcaga aggaaatatc attgaactga agccttttac
     2821 agtttttgtg tcaactttca caccaaatca aggaacgcct gtctttgaag atatgcgtta
     2881 tttcccagaa aagatccaaa tcgttgaaac acagtcaagt gctcaatttt ctaatcatac
     2941 cgctattttt tcagcacctt caaaaggaga atatacgcta gaagtcactt atcgttcgga
     3001 aatatttgat ggggaaaaat ggtctgctca tacagaatct gttacccagc aaaaagcgat
     3061 cactgtgcga gaaactgccg atgtgccccc gggaaatgac aaaccagaaa gagaaaatcc
     3121 aggaaatgaa tcaccaaatg gaaaaccaaa tggaaaacct tctcatccgg ataggacagc
     3181 aaaagaaagt gaaaaaaatg gcactcaagg actcccaaaa acgggagaat ttaataaccc
     3241 gttgctagca ttagctggag gaattttgtt aatcggtgta gttgtttatg tcatgaaaca
     3301 gcgaaaaaaa taagtggaat ttctcctttt atgatgtaaa acaattgact gaggaaagta
     3361 aaaatagaag gaaatgagac caatagatgt ctcacttcct tctatctttt tatagatgag
     3421 gttctccttg ctgcttttga ttggctgttc ttattacttg atgcaggaca gctttttcac
     3481 aatctctcca ctaaacggtg ttcaatcagc tgaccctcgg tattagctca acaaacggca
     3541 aaatatgagg aactattttt ccgttttttt ctctaatact caggtcagga cgctgatttc
     3601 acaacctctc gataaacggt gttcaaaagc cagtttctcg gtagtaagtc aaatttatgc
     3661 aaaaatgtgg aaagccattt tcacaaaatt tttcttacta cttgaaacta agcagctttt
     3721 tcacaacctc taatacatgg tattccagaa gtaacttctt cgaaaaataa gccgaaatgt
     3781 cacaaaaatt tgagaagcga ttttcccaaa ttccttctta tttcttgaag ctgaccactt
     3841 ctggcacaac ctcttaccag attcgcactc ttttttctgg cgctagatac atagcgtctt
     3901 gttccgtgat accaaatgtt tcatagaatt cgtcaaggtt ttttggttgc acgtttgctc
     3961 ggagtttagc aggggcatgg acatcgattt gcagtaaaag ttgttggtat tctttttttg
     4021 cttttgtacg ccaaatcgtt gcccaattga caaagaattc ctcgatagaa agatctgatt
     4081 ccgtttttgc tgcttccaat gcacagctta gaccgcctgc atcagcaata ttttccgaaa
     4141 cggttaattt tccgtttact tttccgtcag caaaaggcag accatcgaat tcttcgatca
     4201 ttgcttgtgc tttgttttga aattgtgtaa gatcttcttc tgtccaccag ttgttcaagt
     4261 tgccatattc gtcaaataaa gcgccgttat tatcaaatgc atgggaaatc tcatgagcga
     4321 taacagctcc gattccacca taattagcag agcttgattg ttctagactg taaaatggtg
     4381 cttgaaggat cgctgccgga aagacgatca cattccgaaa tggatgataa taagcattga
     4441 ccgtgtcagc actcatttcc cattctgaac gatccactgg tttgttccat ttgctgaaac
     4501 gatcttttaa tgtgagtttg ctgaaaacaa gagtatttga aagcaaagta ccaccctgat
     4561 ctgcaggtac tgttttgaac tggtcgaata atgctgggat cttatcgggg tagcctactt
     4621 ggatacctaa gttatttaat tttatgacgg ctttttcttt tgttgcatcc ccaagccagt
     4681 cattttcttc tagacgtttt ttataaacgg cgatcatttt tttcaccatt tgttctacgt
     4741 cttttttagc agcttcgcca aaatattttt ttccgtagta atcgccaact acttgatcga
     4801 attgtccaga ggcaaggtaa tacgctgctt ttttctgagg cattgcttcg tctgttccag
     4861 acaatacgcg agaatagatt ccgctgactt ggcggaattc ttctgataga taaccactaa
     4921 gagaacgtac tgttttaatg atcatccagc ttttgaataa cggaaaatga gcttctgtca
     4981 ggatgtcatt caaatgatcg aagtacactg gatcagttac gatcacttta tctggagttg
     5041 tcccaatcaa acccgtgaca agttttttca agtccagttt atctgtgtat ttaataaatg
     5101 tatcaaaaga ttgcggatta tacattttgc tgtaatctgc gttttcttct gcacttttta
     5161 catgaggagc aatcaattta tcaaattgca ctgcttgttc cgtgattgct tctgcctgac
     5221 ttttttcttt gccggcaagc tctaataact gaacagccat atcaaagaaa acgcctatta
     5281 gttgtgcacc gttgggatgg tctgatgcat aatacgtctt atctggaagg aataaagaag
     5341 gcggataagc aaagaaggcg ttcgtttgcg cattcttcat atctgcatct acatccagat
     5401 taaatggcaa tggtaatgta tccaacagcc attctggaaa ttgcttattc aattcgtcga
     5461 aagactgcaa tgattcaact ttttcgatta taggttgaag cggttgagca tgcaactcat
     5521 ttcttcggtc ataatcgttt gccagttgat aatatgcaag gaaatgtttc attttttctg
     5581 aagacacttt ttctggatgg gcaagcagat cgtctgtttc tcccatcaaa agttggtcga
     5641 tcccgtcaac taaatcttgg aaaccgcctg tagctggttt atctgcaggg atttttgctg
     5701 ttttttgcca ttcttcattg actgcttcat agaaatcttg tttcaatcgt tctttgttca
     5761 ttcatcgatc gctccttttt tgtttcgtgt gcccattatc ttacaaaatg aaggaattaa
     5821 caaatagaac ataaaaaatt gaaaattcga acaatcaaac tgatttgttt ttttcaatcc
     5881 ttcacttata atgaaaaaaa ggaggcgatc ccaactgaat caagtagtgg ataaaccttt
     5941 atatttcaaa gtagataaaa aaattaaaaa attagccagc actcagcagc tgcagtcaag
     6001 aaaaagtaaa ttgctttttt tagctctggt ttttgaagat caaagttatg tgattatcga
     6061 tcaatcagga catccggtag aatattctcc agcaaaatat acttatcaag agggtctttc
     6121 ttgtaaaaaa tggaagctga tcaatgaaga gccaatcgag ttatctagat ggatcaacag
     6181 aaaagaagat attcccgttt tgatcgaaga aaaaaggtca ggaaaggaac tcgcaaattg
     6241 ctgggtggga ttgccagaag aacgtttttt gaggtataag aaatgggcta ccccctcagg
     6301 ctatctttgt ggtacttacg cggcagcagt tctccttgcc tattatcaag actatcgtaa
     6361 ggggtggatg cttccaaatg agattcgcaa gaaaaatacg gctgattcgt tggttttgac
     6421 gaaggcattg cgtagccaga tccaaccact aggacttcct acgattcctt ttcaggttag
     6481 tacagggatt tctagttttt taaagaagaa tggcaatcat gagcgtgcac gagcaactct
     6541 tctaggttca tggcagcgag ctacaaaacg tatacgtgaa ggcaaacctg tgatgattgg
     6601 tattttgaaa gtacttggca gtacatatgg caatcattgg gtgacagcgt acgcttattt
     6661 tgaaactgaa acaggagaac gttattacaa agtacacgac aactggggcg attatcataa
     6721 agtcattcct gccagttgga gtaacggaac agtttcactt ccttaagaat ttgctgaaat
     6781 taacagaaaa tcttggaaaa atatgttaaa ctatcgaaga atagagaagt tttggggagg
     6841 actacatgag taataagtat caggatgaca cgttgaagat ttttagtttg aatggcaacc
     6901 gtccattagc tgaaaaaatc gcgaaagtgt tcggaacaga attaggtaaa agcgtcgtga
     6961 agcaatttag tgatggcgag atttccatca atatcgaaga aagtattcga ggggatcatg
     7021 tgtatatcgt tcaatcaacg aatgcacctg tcaatgatta ctatatggaa ctactgatca
     7081 tgatcgatgc aatgaagcga gcaagtgcga aaacgatcaa tgtcgtattg ccttactatg
     7141 ggtatgctag gcaagaccgc acggcgaaac ctcatgaacc gatcactgcg aaattgatcg
     7201 ctaacttgat cgaagaagca ggggcaactc gagtactgac tttagatctg cacacggttc
     7261 aagtacaagg attctttgat attcctgtag ataatttatt tacgatgccg ttgtttgctc
     7321 attattaccg tcaattaggt ctgacgggag atgacatcgt agttgtttcg ccaaaaaaca
     7381 gcggtgttca gcgtgcacgt agtctttcag aatatttgaa cagcacatta gccatcgtag
     7441 atcatgcaga tgatgcttca actgagggtg gttatgtgat cggtgatgtt caaggaaaga
     7501 catgtatcat ggtagatgat atcttgaaca caggagcaac gcttgcacga gcagcaaatg
     7561 tattaaaaga aaacggcgca aaagaagtat atgcctgtgc gtcacatgga ttattgtccg
     7621 atcatgcgaa aagtatttta gacaatgcac caatcaaaga tatttgtatc actgattctg
     7681 ttttcacaga agaaaatcgt catccagaaa acttaacaat cgttacatgt tcagaattaa
     7741 tgggtgaagc ggtcaaacgc atccatgaaa atacaccgat gagtccgtta ttccgtctgg
     7801 aagaaaaaga attcgaataa acaaaaaaaa gagggaaaga agttgtgaca gaagtgagca
     7861 gcttcaagga gctgcgacaa gacttttgtc acagctcctt ttttctatgc ccatgaaacg
     7921 tcctctagac aaaaatgagc tcttctttgg tttgttcgct attttatgct agaatgtgcc
     7981 tagcaataat ttggaaggga tgaatgaagt gaaaactatt tatctggatc atgcggcaac
     8041 tacccccatg catccacaag taattgaagc gatgacggca atcatgcaag acacgtttgg
     8101 aaatccttca agcatacatg gatttggtcg ccacgcgcat gaaaaattgg aaacagcaag
     8161 acaaatcatt gcagacagtc tgcaagcaaa acctcacgag atcatcttta acagtggggg
     8221 aacagaaggg gataatacag ctatcttaga aacagcgttc tcgcgtcaaa aagaaggcag
     8281 acatctaatc actacagcta tcgaacatcc tgctgttctt aataccatga aatatttaga
     8341 gacaaagggg tttgacgtta catatctgcc tgtagatgaa aaagggaatc tgtcgatcga
     8401 agaggtcaaa aaagcgttac gagaagatac gatcttggtc tctgtgatgt acgggaacaa
     8461 tgaaatcgga aatttgatgc caatcaaaga aatcggtgaa cttttagcgg atcatccagc
     8521 ttatttccat acagatgcgg tacaagcgta cggaaaccaa acgatccatc cagaagaatt
     8581 aggaatcgat ttattaagta tctctgctca taaaatcaat gggccaaaag gcgtcggttt
     8641 cttatataaa cgagacggag taaatatccc tgcattgctt ttaggcgggg agcaggaaga
     8701 aaagcggcgt gcaggtacag aaaatttagc agggatctgg ggtatggcaa aagcagttga
     8761 actgctgtca cctgaagaac gtgaagcacg taacaacaaa tataaaggat tccagcaatt
     8821 gattcttgat acattagaag caaacgaaat cccttatcaa gtaaatggtg atttaacgaa
     8881 taaactccct catgtgttga atcttcgctt aattggcgaa gcaaatgatt tgctactgat
     8941 gaagcttgat cttaatgggg tcgctatttc tactggttca gcttgtacag caggaaatat
     9001 cgagccttca cacgtattag aagcaatgta tggagaagat acaccgatac taaaagaatc
     9061 catccgtatc agctttggtt tgggaaatac cgaagacgac atccagtatt tccttgatca
     9121 attagttcgt gctgtcaaaa aataactagt gaagtcattc ttatatgaac agatgtctga
     9181 gagaacgcct tcatttttta gggaacttaa ctgaaaaacc tagtaaaaat caggataaac
     9241 ttttataata aagagaaact aattttatcg aggtgaaaat catggcattt gaaacaacag
     9301 caacggtact gggcgcacca attagctatc gtttgcatcc tgatgcaaaa agatatacat
     9361 tgcgcgataa tggatttaca gaaacaaacg gaggcaatta tcaattgatc cgaccattag
     9421 atgccacgcc gcaaagcaaa gaaggattca aattaaaaat cactgtatca aaagatattc
     9481 aaacattgaa aatgtcgatc actacagcaa atggattgaa agcagtcaat attttcaaag
     9541 atccaaaaca gaaaatgagc caagataaat tttattttct gatggatggg atgattagcc
     9601 gtgggttatt cgaaaaagtc gaatgatctg tggatataaa aagacaacta gttttgaaac
     9661 ggcctattgt tagatgacta actttgtaag gacgacgcaa attagttgtc ttttttattt
     9721 ttaaatttaa cacatgttgt tatttttaat attttgctga tttattgttt ctaagtaaag
     9781 aaatttaaat tgaaacgatt gttatttagg gaaaaaggta ttttttgaaa aaagaatccc
     9841 gtataatgat tgttgtgcaa acgctataca aaatgaaaaa gaaaagaggg atgtttatgg
     9901 aaaatgaaca gtcggtcgtt ttaacgaatt ggaagagaaa ttatttgttc tttttatcgg
     9961 gacagttttt gtcaggaatc actagtatgg tcgtccaata tgcgatcatc tggtatttga
    10021 caagagaaac cggttcggcg acaattttga gttttgctac tttactagga atgattccca
    10081 tggttttact aagcccattt gtaggaccgc tagtggatcg ctgggataaa aaagctcttt
    10141 tgattgtcac ggatattatt gtagcgattt tcgcgcttat tttagcagta gtcggaacga
    10201 tttcagaatc cttcccgatt tggctagttt ttgtgtcttt gtttatgcgt tcggtcgcac
    10261 aaacattcca aatgccaacg atccagtcga ttatgccgac aatcgttcca tcttctcaca
    10321 taacaaggac gaatggacag ttaggaatgg tccaatcagc gaatttcatc attgcgccag
    10381 ctctaggtgc ggctttgttt tcagtcgttc ctgtcaatta ccttatttta ttagatgtat
    10441 tgggggcagt ttttggtgtc ggcttattga tttttgtgaa gatcccaaaa gtttctcctg
    10501 aaatattgga agttccgctt actattttta aagatgcaaa atttgggctg cagcaattga
    10561 tggataataa agggttatgg tacataacga tcaatggtgc atttgtgatg ctgttgttca
    10621 tgccagcaat cagtctgtat ccattgatga cgctagatta ctttggtggt tccgttggac
    10681 aggcgggagc agtggaagta gtctacgcag tcggaatgct cttaggcggt gcactgatca
    10741 gttttatagg aacatggaaa gaccgaatga aacctattat tatagcctac atcattatgg
    10801 gcctgacgat cggtgcaagc ggattggttc caaacgatag tcaagggttc ttgtactttc
    10861 ttatcttgaa tgcaggagca ggttgtgcaa cgccatattt caatacactg ctgatggcaa
    10921 tgatccagca gagttatgaa tcgaatgttt taggtcgtgt cttagggaac ttcaactctt
    10981 tgatgaacct ggcaggtcca attggattat tatttgcagg accattagct gatcgtttag
    11041 gggtagaaaa aatgttcttg ttttccggaa tcgggatttt attatgcgga atcgttttat
    11101 ttttaacgtc agctgcccga aattatgata aagaattaca gaaaaaactg gtaaaagaac
    11161 accatgagca aaaagacgaa tagtatggaa tggagttgtg acagaagtct tgttacaact
    11221 ccatttctga tcctaatgtt cctgtggcaa taagcctact caaatgaaaa atatgagtaa
    11281 ttatctttat ttgtttaata cttgatatag ggcagttttt tcacgaccta tcgtacttcc
    11341 tctttgcttc atagatttct ttgatttgtt gctcagataa cggagtgcca aatggtagtt
    11401 tttcctttaa gagttctctt tccggtgcgt ctacgcctac attgacatcg ttctcgatag
    11461 gtacgctgta atgatggata tgtccatgaa gattgcggat agtgtcgtta ggcccgagca
    11521 acatcggata atgagtcaag taatattgtt gatggtcgaa tttaacgatg gcacctacat
    11581 cataaaaata aaatttggga cttccgtcag taagcctagg atcatttttt tctaaataac
    11641 ggaaaaaagc gcgactgtca tggttccctt tgatcaagtg gattgttcct tgcagttgag
    11701 tgaccagttc caaaatttct gcatttgctt tttcatattg cggatgcata gcaaggtcgc
    11761 ctagatgata aacatggtcg gtttctttta ttactgcatt ccagctagtg atcaactgtt
    11821 ggttcatttc atccacattt gcaaagagcc gcggagcaaa gtcgtttttt cctaataagc
    11881 gttcatggaa aaagtgcata tcactgataa agtaattcat gtatcttttg cctccctttt
    11941 ttcttagagt aaacaaaatc acttatctga gcaactcata acatctaaaa agaaaaggtt
    12001 gtaaatgaga cgtgcagctt taagcgataa gaagcaattt tgaaaaatag tttttcacaa
    12061 tttataaaat tattccttat tgccgaaagg ctggcccttt ttatgagtat gccaattttt
    12121 tatatcgaat gctcaaaaga tgagtgattt tttggttgac tatcatgttt gtgtactgaa
    12181 taggtccagt agaacagtat ttttacgact tgataattaa gggatgaaat tttcagaaat
    12241 atgacgtata atgtaaaata ctgaaaagtt gcgaccttca actcgtagat gtttcagaat
    12301 ctaattgaaa tgatggtgat atcatgacag acaacagcaa aacacgcgtt gtcgtaggga
    12361 tgagcggcgg tgtcgactca tctgtaacag cacttttgtt aaaggaacaa ggatacgacg
    12421 tgatcggaat attcatgaaa aattgggatg acacggacga aaacggtgta tgcacggcca
    12481 cggaagatta taaggatgta gcgaaagtag ctgctcaaat cgggattcct tattactctg
    12541 tgaattttga aaaagaatat tgggatcgtg tatttgaata tttcctagcc gaataccgcg
    12601 caggacgtac acctaaccca gacgtgatgt gcaacaaaga aatcaaattc aaagcattct
    12661 tggattatgc aatggatctt ggcgccgatt atgtagctac tggacattat gcgcaagtca
    12721 ctcgcgatga aaacggcgtg gtccacatgc ttcgtggagt agacaataat aaagatcaaa
    12781 cttacttcct tagccaatta tcacaagaac agctttcaaa aacgatgttc cctctaggcg
    12841 gcatggaaaa atcagaagta cgggcaattg ctgaacgcgc aggccttgcg actgctaaga
    12901 aaaaagattc aacgggaatc tgctttattg gtgaaaagaa cttcaaacaa tttttgagca
    12961 actatctgcc agcaaaaaaa ggaaatatgg tcactcttga tggtgaagtc aaaggacaac
    13021 atgctggctt gatgtattat acgattggtc aacgtcaagg actagggatc ggtggcggag
    13081 gagattcgca agaaccctgg tttgttgtag gaaaagatct agcgacaaac acattatatg
    13141 tggggcaagg gttccatcat cctgcattgt atgccacaag cttggatgca agtgaaatcc
    13201 actttacgac gaatgaacca atgccaaaag aattcaagtg tacagcgaaa ttccgttatc
    13261 gtcagcaaga cgttcctgtg acagttcgct tattggatga taatcgtgca gaagtcgtat
    13321 tcgacgaacc tgtacgtgca atcactcctg gacaagcagt tgtattttat gatggaatgg
    13381 aatgtctggg tggtggtttg atcgaccacg catatcaaga aacaaaagtt ttacaatacg
    13441 tttaagcgat attaaatgaa tcaaaacagc tatggctaac aaaagaaaca ccttttcttt
    13501 tggatagcat agctgttttt ttgcaataaa attaattttt attcatttta tacttgaaat
    13561 acttgtgtaa aaagttcata atatccaata atatgaataa agttgctttt tgttaagcaa
    13621 gagcagttgc aaaatagaag ggaatctttt gcaagtgatt tgttcaattt tataagtgag
    13681 ggtgatggaa atggaaaaga aatcgacggg tattagcaaa tggggactgg ttgctctggt
    13741 tgtcagttcg tcaatcggaa gcggtgtgtt tgggatcaca agtgatctgg ctagttctgc
    13801 agctccaggg ccagcgatcc tttcatggat aatcgttggg attggtattt tagctttggt
    13861 attatcgctg aatcatttag gagaaaagcg tccagatcta gatggtggta ttttcggtta
    13921 cgcggaagct tcatttggta aattaggtgg cttcatcagt ggttggggtt actggttgtc
    13981 tgcgtggctg ggaaatgttg cttttgcaac gatgctgatg agcgccatgg gagaattttt
    14041 cccgatattc aaaggtggac aaaatgttcc ttctatttta tttgcaagta tttttatttg
    14101 gggtctgact ttattagtaa acaatggagt tgaaggagcg agcgtcatca atacaatcgt
    14161 gacgatctgt aaattagtgc cattattcct atttttaata tttgtattta tcgcatttaa
    14221 agtgaatata ttcactgctg atttttgggg taacgtatct gataatctag tgaatggaac
    14281 agggcagcaa ggaacgatct ggttgcagat taaaggttgt ttgatggtta tgatgtgggt
    14341 ctttgtaggg atcgaaggcg caagtgtttt agccaaccgc gcgaagaaac gttcagaagc
    14401 ccagcaagca tcgatcattg gtctgctttg tttattgttt atctatatcc ttgcttcgat
    14461 cttgccatac ggcgtcttat ctcaagaaga gttagcaact atttcacaac ctgctatggc
    14521 aaatatttta aaaggaatcg tgggaaattg gggagcagcg ctgatcaata tcggcttgat
    14581 tatttcgatc attggttctt ggttgtcttg gacgatgctc ccagcagaaa caacgatgtt
    14641 gatggctcga gacggtctgt tgccgaaagg ttggggaaaa acgaataaaa aaaatgcccc
    14701 aacttattcg ttagttgtta ctgcaatctt gactaatcta ttcttattga ctttcttagt
    14761 tactgattat gcctatcaat ttgcctattc tttatgtaca gcggcaattt tgatttgtta
    14821 tctacttgtc gggatctatc aagtccagtt ttctttaaaa gaaggaatca aaaaacaagt
    14881 agtgatcggt gggattgctg tagtttttga attgatgggc atcattttag caggattttc
    14941 ttatgtcctt ttatgtagta ttgcctatct tcctggtttt tgcttctact ggatcgcttg
    15001 tcgtgaaacc aaacatcaaa ttacgggaaa agaaaaagta atgattgggc tgatttgtgt
    15061 ggccgcactg ctttcaatcg ggttgcttgc tgtaggctgg atcaagatat aagggggaaa
    15121 gaaacatgaa aatcgcaaat ttcggtgtag aagaatggct aaataaatgg gaaaagaaag
    15181 cggtatatga tattgcacaa agctcgatcg aagcattgac attagacgaa ctcgttggct
    15241 tagatgggac tagcgtaagt aaatttttcg aaaaacgcaa aaacgaacca ttggactatg
    15301 gctggatcga aggatcagat gttttcaaac aagaagtcgc ttctctttat caaaccgtcg
    15361 atccggaaaa catcttacaa acgaatggag cgactggtgc taatctttta gctctatacg
    15421 cgttagtgga agcaggagac catgttgttt cgatgcttcc tacttatcag caattatatg
    15481 acatccccaa atctttaggt gccgctgttg actttgttca tttgaaggaa gaagaagatt
    15541 ggcagtttga tttagaacag ctagaagcct tagtcaaacc tgaaacaaaa atcatctgtt
    15601 tgaatagtgc aaacaatcct acaggcacat tgctagatcg gaaaacttta gaaaaaatcg
    15661 cagaaattgc tcgtacagta gatgcatatg tattgataga tgaagtatat gcgcctttaa
    15721 cggataaagg tgaattcttg tcgatcgtag atgtctatga aaaaggtata gcaaccaatt
    15781 ccctatccaa aacctactcc attccaggta ttcgtattgg ctggacagct actggacctg
    15841 agttggcaga agtttttcga aagtatcgag actacacgat gatttgcggc ggagtcctgt
    15901 cagatgatct tgctgtacat gcattgaaga ataaagaaaa aatattggcg cgaaacaaaa
    15961 agatcattac agagaacctt gtgattttaa aacaatgggt agccaatgaa ccgaaagttg
    16021 aacttgtcgc tcccaattac gtctctactt ctttcattaa attagccatc gaagaagatg
    16081 accagacatt ttgtatcaat ttattagaag aaacaggagt actattagta ccaggaagtg
    16141 cctttgattt accgaagcat gcccgactag gttactgttg taaaaaagaa accttggaaa
    16201 agggattatt cctcttatct gagttcttga aaaaacaggc ctaaacaaaa acactgcaag
    16261 gacagtctgt gacaactgtt caagcagtgt ttttcattta cgcttattgt ctatgagaag
    16321 gagagtgccc tgaagctatg gagactcctg aagctttttc ttctgcagtt tcttgctgat
    16381 ggatctcttg tgtattgtgt cgtacaagca agaagttgac caaaacaaga agagaagtcg
    16441 aaagaaagac gccgcgataa ccaaatgcac tggaaacact ggagccgatc ataggcccta
    16501 ctacgttacc agttgcttgg aaagattggt tataactgaa gatccgtcca gcagcttgat
    16561 gaggcgaata ttttgtgatc aatgcttgga cagcagggag cagacaagca tcagagatac
    16621 caatcaaaaa acgtaaggca gctaattgcc aaacattcgt gacgaatgcc attgggatat
    16681 aaaccagaat cgcaaaaccc aaaccaatcg caagtattct ttcactccca atcttgtcac
    16741 ctaagcgacc aaatcttgga gcggctatca aagtggcaat cccaggtatc gaagcaatga
    16801 ttccgctgat caacgtaaca ttcccatgtc catgcagcaa ttggcgaatg tacagactga
    16861 tgattggact aatggaattg ttggatgctt ggatgatcat cgttgtgacg aacataccga
    16921 tgacgacgtg tggatatttc aagtctttga aaatctgttt ggcagaaacc atgttttctt
    16981 ttttcactgg gacaaatttt tcatggacga aaaacagact caacaagaag acgaaaaata
    17041 agatgatccc tgtaatgaaa aaggtagggc gatagccaaa cgctgaagca gagatcccgc
    17101 caagaagcgg tccaagtaat gttcctgtaa cagaaccagt tgctaaggtt ccaagaactt
    17161 gaccactttt ttcttttggc gtcccagttg cgacaagggc agtggcatta ctgatataac
    17221 cagaaaaaat cccttgaagc agacgcaatg cgactaattg atacacacta gtcacgcaac
    17281 ccatcaaaga aatgacgatt gccattccta atgaagcacg caacagcatc aattttcttc
    17341 ctttttggtc ggctaatttt ccccaccaag gagagataag cgtagtcacc aagaaagtag
    17401 atgaaaaagt caatccgctc caaaagttca attgtgacgt actataatta cctaacgtat
    17461 ctatgtaaag tgacataaaa ggcatgacta aactaaatcc gataccagcc ataaatgttc
    17521 caaaccataa gacaaacaag ttttgttccc aagtttctct tttcctaaat aatttttcct
    17581 ttattcttgc agccaattag actccttctt tctgaaaatt ttcatctaca gctctttatt
    17641 ataaactaca atatgtagtt tatcaatgaa agtctctttt ttctctttct ttttcgtggt
    17701 aaactgaaag agtgaaggat ttattttatg agaggaaaca tggaaatgaa aaaaagaaat
    17761 ctgtctcaag agaaaatcat cgactgcttt cgagaactag cagaagagat ggatgttcag
    17821 caaataacct ttcagcattt agccaaacgc ttggatatca aggctccctc gctgtataac
    17881 catttcaaaa atattcgtga tgtcaaaaca gcgctaacag cgaaacttct gcaggaactt
    17941 aatgaccagc tgcgacgggc tcttgtggga aaaagtggtc aggaagcact gcagatctat
    18001 gcagaaactt atcgatcctt tgctttttca aatcaagcag tgtatgagtt actgatcagt
    18061 gtaccgcata ccaatgaagc tgttttatta gatggaatcc atgaaacgaa tcagatcatt
    18121 ttgcagatat ttgaggcttt tcaattaacg aaagaagaaa aagttcatcg aagcagggaa
    18181 cttcgtagta tgatccacgg ttatctttcc ttacgttttt taggatactt tacaaaagaa
    18241 ccaacaatcg atccagaaga cagctatttt tggatgatca ataactttat cgctactttg
    18301 ccttaaacaa tcagattcat ttgtaacaat tttaagatgt tcattaaatg acccttttat
    18361 aagagaaaat tcttgcaact ttcttgaaaa gtgactaaga tgagtctaga aaagctgaaa
    18421 gaaggagcac gagtatgtat caagtaatta ccatgttcgg ggacaatgag ccttggtggt
    18481 tttttgaaga ctgggaagaa gatattgaag aagaagaaac attcgagtct ttcgaagaag
    18541 cacgacaagc gtacgaaaaa caatggaacg aaatccatca aaattatgaa tatatcaatg
    18601 caaaaagtaa ctttctcagc gccttttgga atgacggaga tgagcgctgg tgtgaagagt
    18661 gtgacgatga tttacagcaa tacaagggac ttgcgttgtt gaaaaatcat cagcccatca
    18721 cagtagaaag cagaaaggaa ttttatgaaa caactaattc tagcggaaaa accaagcgtt
    18781 gcgaaagacc taagcaaggt gcttggtgct aatcaaaagc acaaaaatta ttatgaagga
    18841 cccaaggtga tcgttacttg ggcccttggt catttattag gattgaaaat gccggaagat
    18901 ctgaataagg aatggcagag ctggcaaatg gacacgttgc caatgatccc taaaaaacta
    18961 ggaatcaaac cacttcctaa aacaggacat caattaaaag caatcaagca gctggctcag
    19021 cgaaaagatg tctcagaagc agtcattgcg acagatgccg gaagagaagg ggaacttgtt
    19081 gctcgctgga tcttagagta tgtgcatttc aataaaccag tgaagcggtt atggatctct
    19141 tctcaaacag ataaagcaat caaaactgga ttcaagcaac taagacctgc gaaagaatat
    19201 gatgcattgt atgaatctgc tcttgcccgg gcaaaagcgg actggctggt aggattgaat
    19261 gtgaccagag ccttaactgt gaagtacgcg gataatttat cagcaggccg tgtgcagaca
    19321 ccgacactag cattagtgag agaccaagaa aagaaaatcg agcagttccg tccacaaacg
    19381 tatttcacga tcacgttgca agctggaaaa gaacaagcca aaatgcttca aaaaaatcaa
    19441 tttgctttaa aaacacaaga agaagcacaa aaacttgttc aattgatcag tacaagcaaa
    19501 ggaactgtca cagaagtcca agaaaaatta aaaacggaat ctgcgccatt gccttatgat
    19561 ttaacagaga tccaaagaga agccaatcaa cgctatggct attctgcaaa gaaaacatta
    19621 agtcttgtac aaagtttgta tgagacccat aagatcgtta cttatccgcg tacagacagc
    19681 aaatatctga caaatgacat gaaaagtacg atgaaagaac gattgcaagc agtcagcgac
    19741 tttgctcctg aggtcaagca gtatttgaaa aacggagcca tcgtccaaca gacaaaagta
    19801 ttccaagaca gtaaagtgac cgatcaccat gcacttttgc caactgaaaa cagagcacgt
    19861 tatgaaaaat taagtaatga agagcgaaaa atctatcaaa tgattgtctc tcgtttttta
    19921 ggactgtttg ctcaacccca taaagtcagc caaacaaaag ttacggttga atttggtaaa
    19981 gaacgattca tttttcggca aaatcgtgtc gtccaagcag gatggaaagg cgaaactgaa
    20041 actgagacgg aaacagtcaa atgggaaaaa ggaatgagaa tcaatcccga tttcgccatc
    20101 aaaaaagaac tatctgcacc gcctaaacca ttgtcagaag caagcttgct tggtcaaatg
    20161 gaaaaataca gtctgggaac cccagctacg cgtgcagaga ttatcgagaa actaatcaaa
    20221 tctgaactga tggaacgtac ccctcaagga ctgcaagtat ctcctaaagg taagcaatta
    20281 ttagtattgg taaatccctc tttagtaaca ccagatttga cagaaagctg ggaaaaagac
    20341 cttgaagcta ttgctgcagg aaagaaacaa gcaggaacct tcttgaatgg aatcgaaaaa
    20401 gaaacaaaac gcttggtgaa tgagatcaaa tcaagcaaac aagaatatca agatttctcg
    20461 attacccaaa agaaatgccc agaatgtggg gccaatctgc gcgagaaaaa cacacgtgac
    20521 ggcaaaatct atgtctgcac caattcagat tgcaactacc gcagaagaaa agatccaaaa
    20581 gtctctaatc atcgatgccc gcaatgtcac cggaaaatgg aaatcatcga aggtaaaaac
    20641 ggtgcttatt tccgttgtaa atacgatgga acgacagaaa aattgcttga taaaaaagag
    20701 cagaagaaga aaatgaccaa acatgaagaa cgacgcttgc tgaaaaaata tgcacaagca
    20761 gaagaaccag aagaaagccc attagcagca gcactaaaag cagcaatgaa gaagtaataa
    20821 gatatgaaag aggttgtgat agaagtggtc agcttcaaga aataagaagg aatttacgaa
    20881 aattgcttct caaatttttg tgaaatttcg gcttatttcc gaagaagcta cttctggaac
    20941 accatttatt cggaaaaaag gactgtgaca agacttttgt cacagtcctt tttcatttaa
    21001 aaaaatgttt acttcatttg acgtatatta ttggtgaggc ttcaattcat ttggcttcac
    21061 tttttctgtt tctcttatga tataaacagg acgctgtttc gtttctaaga agattttccc
    21121 aatatatttc ccgatgattc caagacataa caattggatt ccaccaatga acaggaagat
    21181 cgagaccatg gaaggccatc ctgatgtagg atcaccaaac aacaatgccc gcaaaataat
    21241 gaacaaaatt gcaataccag aaccgacaca agacaaagcg ccgataaatg aagcaatcgt
    21301 taacggtgca tccgagaagt tcacgatacc atcaatcgag tagttgaata atttccagaa
    21361 ggaccaagat gtttcgccag ccacacgttc gcggttttca taagaaatat attctgtttt
    21421 aaatccgacc cagctaaata atccttttga aaatcggttg tattctgtta attctaggac
    21481 ggcatccacc atttgacgag tcatcaagcg gaaatcacga gcgccatcga ccatttctgt
    21541 atcgctgatt ttattgatca actggtagaa ttttttcgca aagaaactgc gtatcgcagg
    21601 ctcgccttca cgagtcgaac gccgggtgcc gacacaatcg atatcagaag tagtgatccg
    21661 gttgatcatc tcaggaagca gttcgggcgg atcttgcaga tcaacatcca tcacggtcac
    21721 taaatctcct gtagaagctt gcaatccagc gtacagagcc gcttctttcc caaaatttct
    21781 ggaaaatgag acaaagcgga cataaggata agctgaggct agcttcttga ttgctgctaa
    21841 cgtaccgtct tttgatccgt cgtcaataaa caaatattcg aactcatggg cacctttgaa
    21901 tttttcaacc tcatcaaaaa aaagaggaac agttttttct tcattaaaac atgggacaac
    21961 aattgatact ttcatcgttt ctatcctttc aatcgtatgt ttatatatgg tttacattca
    22021 aaatttaata aaccttaaat aacaccttta aaatttgatt ttacgtaaaa gaacaggtat
    22081 tctttttgta aactaacgta tttagtttac catgtttcct cggtttatca aacttttaag
    22141 aacaattttt attagttggc aagtagtttt ggatagagaa aaaggaggaa gttccagtct
    22201 attgactagg agcaaacaaa atgaaaatac acacacctat cggcttttta tggttagatg
    22261 cagatgaatc cggattgact gctgtatctt ttcagccaat ttcagaaagc gaatcagcga
    22321 atcagcgaat tttaacgcgc acacaagaac agtttgaaga atattttgcg ggaaaaagaa
    22381 aagaatttga tgttccttta tctataaaga gaggtacgcc ttttcagcaa aatgtctgga
    22441 aagctttgtc gaccattcct tatggagaaa tccgaacgta taaagaagta gccgttgctg
    22501 ttgatagtcc gaaagctgtg cgagcgattg ggcaggcaaa tcgaaccaat ccattgccaa
    22561 tcgttattcc ttgtcatcga gtgatcgggc aaaatggaaa actgacagga tatatgggaa
    22621 acgcaataga tggggttgaa atcaaacgcc aattgttgtt gttagaagga tatctgcaaa
    22681 attaaaaaca gttgtgattc ggacattgtt ccatgcgaga atcacaactg ttttttcatg
    22741 ttcattctaa actttgatca gccaaataaa tagtaaagcc atcactgttt ggagaagccc
    22801 gacagctaat ccataagata agaagcgtgt accttctttc atgaattttg caaagtctaa
    22861 acgcagacca attgccgcta aagcagtgat ctcaaaccag ctgctgataa aatgtgccga
    22921 ttggtcaata actacaggta aagaaaacaa gctgttgacc aaacaaaaga tcacaaaccc
    22981 taatacatac caaggaagcg gtaattttcg ttttttctgc gtatcagttg gcgtttcaaa
    23041 cagagctggt tgtttcttgt gcatgaattt ttcaaacaga tagacaacaa caacgagcat
    23101 cataatacgt agaatcttaa atagcatggc gaattcgaca acagaattgt caagtaagct
    23161 tgccccagcg actacttgac caacagattg gagtgtacca cccaaaagtg cacttttttc
    23221 aatgagattt ccaccaaaca actgtaatcc aagaaaaggg agagtcaaca tcatcacagt
    23281 acccagtaga ttgactagtg tgatgatctg tcctttttct tcctctttcg catggatgga
    23341 aggggcgatt gaagcaatag cagaagaacc acaaacagcg tttcctccag ccatcatcaa
    23401 agaagaagta tcgctgaatt gcagtttttt accaatcaag taagcaccga tgatagtgac
    23461 tgacatttgc agtaacacaa aaacaattcc ttttacacca atttgagcaa tcgtttgagc
    23521 tgtgacagtt gcacctagta aaaaaacaga gaattctaat agtttgcttt cagcaaattt
    23581 tgtgccgatt gctagaacag gctgtttaaa aaaagtattt cctaataaaa tacccaataa
    23641 aatagcaata gtcgctccac ctaactgtgg cagataaata gcaagaagcc tgctgaaggc
    23701 agcgatggca aaagaaagca gtaaaccggg taagatttcg cggaccgctg aatcctttac
    23761 agattttatt ggatgtgaca atgatttcat ttgatcggtt cctttcgtca ataaatacta
    23821 aaagcatact cgaacatagt agcactaaac cagtattttg acaaaagaac aagaggtcgt
    23881 gacaaaagtc ttgtacgacc tcttgtttcg aataaacggt gttccagaag tagcttctac
    23941 ggaaataagc cgaaatttca caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt
    24001 tcttgaagct gaccacttct tttacgacct cttggtaaac ggtgttcaaa agcttgcatc
    24061 tgcggtaata agcccaacca gtacaaaaac atgaacagct gtttttgttt ggccgttctt
    24121 attacttgat gcagaacagc tttttcacaa cctattgaat cgattattaa gcgatttttt
    24181 tagaaacaaa ttttccatgt ttgctatgtt ctttaattaa gaaacgtacg taatgagcaa
    24241 gaacgtagaa gacaactaca cttgcaaaca gacattccgc aacttttaag aaatccaata
    24301 cgctactata gatacctaaa ctgttgaagt aatgaacagt agtaaatata gctgttgcag
    24361 agataacaag cgggaatgta aaggctgcat agcttggata aaaacgaagc ttgaacaaac
    24421 gtggaagcat agacagcaca acgaaataca atacttgaga taaagcgaac aatgctacga
    24481 caagataaaa attaggttca gcaaagtttt taagataacc tgttaggcaa agagaaccag
    24541 gtgctgcaac gatcgtaatc agcggacgtg tcggatgagc catatttctt acgaaaaaga
    24601 cacgtttgat gatgatcggc aataagaacg catagcagat caatgaaatc caaaagaaaa
    24661 tttttccaat aagtgggaag aagttcccgg cagttacagt gatgacccca aatccaacgt
    24721 aaatgataaa ccagcttgga taaattgctt caattgaaag atcagctttg ataacatggt
    24781 gataattgaa ataaaagaca aggatcactt ggaagataac agcgcacagc caaatgaatt
    24841 tgacaattgg tgcaatactt tcatatgaaa caaaataagt acaaataacc atgagtgaca
    24901 tcgtaaaagt tggtgaaacg gaggcgatga ttggatcatg caacgtttgt ttcgtgtgtt
    24961 cgaataagat aaacaattta acaaaaatga atatcataag aatcatagag ataccgccag
    25021 ttagattgcc taaagcaaca tggtgatagt ctttaaacag atttccaagg gaagctaacc
    25081 caaggatcaa cccgcagatc gggatcggaa taattttcaa aaagttcttc atatataata
    25141 ttctcctttt tatttaatag attttagtac caagatgaac gaatacattg taaaatgaat
    25201 aggaatgtat gattacgagc aagcagacag ctgattgtct tcatctaagt tactagttgg
    25261 atcagcaact gttttgttgt acatttctat tatagatggt tttttgtata tttaaatcaa
    25321 atagttttta tagtaattat cataaaaagt tatggaagtg gtgccatgtt taagttatta
    25381 acgacttttc gagcagtata tgaaacaaga aatttttcca gagcagcaga agtactgttt
    25441 ttatctcaac cagcagtctc gaatcaaatc aaacagttgg agcgggaatt gaatatcgat
    25501 ctttttcaac gtaacggaag aaaagagatg cttccaacta agcaagccga cttattatat
    25561 gaacggacac tggttttgtt agaagaatgg gaagaaactc agcaaaaatt gctcaatgaa
    25621 caaaatgaag aagaagtatg tcggatcgtt gcttcccaca cctttgctgt ctatcttttg
    25681 cctcagttga tgaaacatct gatcaaaagg tttcctaaag tgcattttga gatcgaaatc
    25741 acgaattctc atgaatcatt agaacaagta gcgaaacatg aatccgattt tggttttatc
    25801 gaaaagccat tagagacttc cggcgtacaa agatactctt tgatggaaga ccagctagtc
    25861 atcgctgggg acccaaaaag caaattgtgg cttgtaagag aagcaaactc tggtgttttt
    25921 cattacacgc agcgttattt tgaagagatg aatatccaag ataagaagat gatcgtgaaa
    25981 agtaacgatg taattgttgc gttgctgaag gaaggaatcg gtcgctcgat tttgtctaag
    26041 cgctctgttc cagaaaatgt gccaatgact ccgttgaatt tccatcgata tttttatttc
    26101 atccaacgaa ccaatctggt ttctgatcag ctgctagaga ttgccgaaga gatccttcga
    26161 tacaatgaaa gcacagaaac ttctcacagc gaggagaatc tcagctggta gataattgca
    26221 tgtatcaaaa aaagttctat gatacactaa agataagcag taggcttttg tactgcattt
    26281 gctcaagcaa ctgcacaaac ggaaagttaa tttttcccaa atgtctatgg aaagactttc
    26341 cattatctaa ctggaccgct ataataatca gcagtatggt ttttaagaaa agggatgaaa
    26401 catggaaaaa aaattaaaag cttcgaacga taatcgtatt gattatggcg tgattttacc
    26461 agtctttctg ttatgtttga ttggtctgct ctcattatat gtagcactta gccatgatcc
    26521 gaacaatcca gcagtcttga aaggcgtagg gatgcaagtt gtctggtatt tagttggagc
    26581 ggcagcaatc gttgtcatca tgcatttgaa ttccaaatgg atctggaaac tgactcctta
    26641 cctttatggt ttggggttag tggtaatggg actcttgctc aaattctatg atcagaattt
    26701 agctgcttca acagggtcta aaaactggtt tcgattcggt gcgtttactt tccagccagc
    26761 agagttgatg aagattgcgt acatcttgat gatggcactg atcgtaacta aacataatac
    26821 gcaagtaaaa gaacggacga tgaaatcgga cttttggctg attgggaagc tcttgatcgt
    26881 gacaataccg gttttagcat tgatcatggc ccaagatgac tttggaacga tgcttgtctt
    26941 tcttgcgatc tttggcggga ttttcctgat gtctggaatc tcttggcgca tcatcgcacc
    27001 tgtagtaatc ttggcagtag tcgttggagc aggaacgatc ttcttggtta cgactgaagg
    27061 cggaagagac ttgctttata aagttggatt caaatcttat cagtttgcac gtattgattc
    27121 atggctggac cctttccatg atacgtcagg aatgagttat cagccggccc aaggactttt
    27181 ggcaattggt accggtggct tgtttggtaa aggattcaac gtaagcaata tctatgtgcc
    27241 tgttcgtgag tccgatatga tttttaccgt tatcggtgaa aacttcggct ttatcggtgg
    27301 tgcattcgtc attttcttgt attttatttt aatctatcgt atgattcggg tgtgtttcga
    27361 tacgaataat gaattttacg cctatatcgc aagcggtttg atcatgatgc tgctgttcca
    27421 tgtctttgag aatattggag caaatatcgg attacttcct ttaacaggga tcccattgcc
    27481 tttcattagt cagggaggat cctcgatttt agggaacatg atcggtatcg ggttgatatt
    27541 atcgatgaga taccaaaatg aagcacctgc aagatcttca aggaggtaag aaaattgtac
    27601 accttttact ggtacccgaa atgttcaaca tgcaaaaaag ccaaagcgtg gttagaccag
    27661 catggcgtta gttatcaaac cgttgatatg atcaaagaag taccgaaggc ctcaacgatt
    27721 gagacttggc tagaaacgag tcaagtacca atccgtcgcc tgttcaacac aagcgggatg
    27781 aaatatcggg aacttggact gaaagatcaa gtaggcgagt ttacggcttc aaaagcgagc
    27841 caagtcttat cgacagatgg tatgctgatc aagcgaccac tgatcttacg agaggaccag
    27901 cttgttgcaa ttggattcaa tgaaaaaatt tatgaaggag aactgatata aaatggcagg
    27961 caagcatttg aagaaaaagg acaacctttg gatcttattt aatggaaaag aatactgtgt
    28021 tggtttgaca aatgaagcgc aagaagaact tggagacatc acgtttgcca atctgccaaa
    28081 agcaggacaa tcgctaaaaa aagatgaacc tctgatcgaa gttgaagcgg aaaaagcggt
    28141 caatgaattt gccagcccgc taacgggtac agtttcttct gttaatgata aaatcggtga
    28201 agatatcaat atcttgaatg attcagatga aatgaatgcg tggatcttaa gtttcaaaga
    28261 tgttgatcca aaagaatttg acgaattata aaatcagaaa atcacttgaa aaaagttgac
    28321 actgattctt ccagttgcta taatcataag caatcctata tgaaacgaga aagctttgaa
    28381 aagaagagta catgtcacgg acgtttgaag agagccctgt ttgctgaaaa tgggtaacga
    28441 aaatgagatg gaagatggtc ttagagcaga gtaagcgagc gtaagcaaac ttactacggg
    28501 agtgcccgtt acagcgcgac agtatacgga aagaagctaa gtccaagtac tggaagaggc
    28561 tgttattgcg aagtaacggt aaatcaaggt ggtaacacgg aagttcaagc tttcgtcctt
    28621 ttgcttaagg caagagggcg aaggcttttt tgtttgaaaa attataagag aaagatgtga
    28681 atggcatgtc attaatccaa ctaacgaatg tcaaaaagac attcaatggg aaaaacggaa
    28741 acatccaagc cgtcaatgac gtttcactaa acgttgaaaa aggggatatt tatggaatcg
    28801 tcggctattc tggcgcagga aaaagtacat tagtccgtct cctgaatgga cttgagcttc
    28861 ccacgagcgg cgaagtgatc gtaaacgatc aagatattac aaaattaaaa aacaaagaat
    28921 tacgtacatt ccgaaagaaa atcggtatga tcttccagca tttcaacctg ttatggtcaa
    28981 gaactgtact tgaaaatatc cagctgccgc tggaattagc tggcgtacca aagagcaaac
    29041 gtaaagaacg ggcagaagaa ctgttgcgtt tagtcgggtt agaaggacgc ggacaagcat
    29101 atccttcaca actttccggc ggacagaaac aacgcgtcgg tatcgcacga gcattggcaa
    29161 atgatcctga gatcctgctt tgtgatgagg ctactagcgc attggacccg caaacaacag
    29221 aagaagtatt agacttattg ttagcgatca ataagaaatt gaatttgacc atcgtcttga
    29281 tcacacatga aatgaatgtg atccgcaaaa tctgcaacaa agtcgctgtg atggagttgg
    29341 ggaaagtcgt agaagaagga gacgtattga ctgtcttcag acaaccgaaa aaagaagtaa
    29401 ccaaacgctt tgtacaacaa gacatcgaac cagaagctga ttcgacagaa ctattagctg
    29461 aactcatcaa agaaaatcca agcggccgtt tggcaacttt gacctttagc gaaagaaatg
    29521 ccaacgagcc agtcatttcc caagcgattc gacgctataa catcgatgtc aacgttgtgt
    29581 atggaaagat caaacaagtg aaagaaggtt cctttggttc attgactgtc ttgatgactg
    29641 gtgaaaccaa agaattagat caagcagaag tgttcatcaa agaacaagga gtaggaattg
    29701 aggtgatcca tcgtggataa aagcttttca gaaacatatc tagattttaa acaaatcaac
    29761 ccggaaacga tgaatcaggc tatccttgat acactatata tgacattaat ctcaatggtc
    29821 ttagtgacga tcatcggatt agttttggga ttgatccttt actctattgg acgcaaaaac
    29881 aaaccgtatg ctcgaatcat ttatggaatc gtatcgatca tcagtaatat tttccggtca
    29941 acgccattta tgatcctgat ggttttgatc attccattta ctaaagcaat cgtaggcact
    30001 atgctaggtg cgcaagcagc cattccagct cttgttttat ccgcagcacc attttatgcc
    30061 cgtctagtag agattgcttt tcgtgaagtc agccctggtg tactggaagc agcagatgca
    30121 atgggagcaa gttactggga aatcatctgg aaggtcttga tacctgaaag tattcccgca
    30181 ttgatttctg gattaacagt tacaacgatc tcgatgatcg gatttactgc gatggccggc
    30241 gcgatcggcg caggtggact tggaggtctt gcttggcagg aaggctacca gcgtggtaat
    30301 ctaacagtga cattcgttgc gactttaatt attttactaa tcgtatttat cgttcaagga
    30361 atcggtgatt tcttaactaa gaaaacagac aaaagataat aggatatagg gggatgtagg
    30421 atatgaaaaa gaaaattttt ggatttgcag cagcgctttt gctgactgta ggattagcag
    30481 catgcggtaa caacagcgac agcaaagatt cagcaaataa agcagacgac acgacattga
    30541 aagtcggcgc ttcaccgaca ccgcacgcag agattttgga acatgtgaaa ccattattga
    30601 aagatgaagg aatcgatctt gaaatcgtca aattcgatga ctatgtatta ccgaaccaat
    30661 ctttggaaga aggcgacatt gatgccaatt acttccagca tattccttat ttgaacaaag
    30721 aaatcaaaga aaaaggatat gactttgtca atgccggtgc tgtccacatc gaaccaatgg
    30781 gcttgtactc taaaaaagtc aaagatgttt ccgaattaaa agatggtgca acaatcatta
    30841 cttcaaattc tgaatcagac tggggacgca tcatcacaat tctacaagat gctggcttag
    30901 tcaaagtcaa agatggagta gatctggaaa cagcaacatt cgatgatatt gaagaaaacc
    30961 ctaagaactt gaagttcaac catacgatcg acccatcact tttagcttct acgtaccaaa
    31021 atgatgaagg tgacctagtt gcaatcaacg caaacttcgc ttacggcgca gggttgaatc
    31081 cattagaaga tgccgtattg cttgaaaagg acaactctcc ttacgtgaat attattgcga
    31141 ctcgtaaagg tgatgaagac agtgacaaaa tcaaaaaact gattgaagtg cttcaccgca
    31201 aagaagtcca agaatggatc acagacaaat ggggcggctc tgttaaacca gtaaaggctg
    31261 atgcaaaata aggtatggaa caaaaaagat gagaaataag tctgtaatgg cttatttctc
    31321 atctttttta tacctattct aatttagaaa tcaaaattgt ttaataataa ataaaagata
    31381 tttgatttta gtaaggaagg tcattgcgct tcattctcaa ttagtctaaa atgagtgaga
    31441 acgaaagaga atttgggggt ataatgcatg tctgtcttag aaataaaaaa tctacatgtg
    31501 tcgatcgagg aaaaagaaat ccttaaaggc gtaaacctaa caatgaaaac cggagaaatc
    31561 catgccatca tgggacctaa cggcacagga aaatctacct tatctgccgc tatcatgggc
    31621 aatccaaact atgaagtaac agaaggcgaa attttgtttg acgggaaaaa tgttttagac
    31681 ttggaagtag atgaacgtgc gcgacttggc ttatttttag ctatgcaata tccaagtgag
    31741 ataccaggta tcacgaatgc ggaattcatg cgtgcagcga tcaatgcgaa acgtgatgaa
    31801 aacgacaaaa tttctgttat ggcatttttg aaaaagttag atgaaaaaat ggctttacta
    31861 aatatgccag aagaaatggc tgaacgttat ctgaacgaag gtttttctgg cggagaaaag
    31921 aaacggaatg agatcctgca attgttgatg ttagaaccta catttgcaat tttagacgaa
    31981 atcgattcag gtctggatat cgatgctttg aaagtcgttg ctaaaggagt aaatgaaatg
    32041 cgcggagaca atttcggtgc attgatcatc acccactatc aacgattatt gaactatatc
    32101 acacctgatg tcgttcacat catgatggaa ggccgagtag tcatgacagg gaatgctgac
    32161 ctagctaaac gtctggaagc agaaggctac gctggtatca gtaaagaatt aggaatcgac
    32221 tataaagaag aagaagcgta agggggagca agaatgaaag aaaaaaactg gctcgattat
    32281 cttgacgcgg taaatgattt ttctttaagt aaaggcgaac ctgattggat gagaaccttc
    32341 cgtcaagacg cactagcgaa agcagatgaa ctgccattgc cgcatatcga tcgggtgaaa
    32401 ttccatcgct ggtcgttatt tgatgtgaaa gaaacacaaa ccatcagtga aacaggcacg
    32461 attccggcat ttgatgcaat gaaagacaat cctgtgcttg tccaacaagg ttcatggacg
    32521 atttttgaac aactgcctgt ggaattagca gaaaaaggag tcatttttac cgacttgttc
    32581 actgcaatga tcgaatatcc agaactagtc caagaatatt atatgaaaaa agcagtaaac
    32641 atgaacgaag accaattgac tgcactccat gtagctttta tgaacagcgg tattttcctg
    32701 tatgtgccta aaaatgtcgt gatcgatgaa ccactcgagt ccttattcat tcaagatggc
    32761 gcatccgatg agcacttctt caagcatgtg ttgatcgtgg cagatgaaca tagtgaattt
    32821 tcttatctgg aacgtttcca gacaaccaaa gaacaagtag caaaatcatc aggtaatatc
    32881 atcgtggaag tcatcgctaa agctggttca aaaatcaaat attcagccgt agatcaatta
    32941 ggagaaaata ttacttctta tatgaatcgc cgtgggcaca ttttacgaga tgcttctgtc
    33001 gactgggcaa ttggtgtcat gaatgacggt catgtgatcg ctgactttga ctcagattta
    33061 gcaggagaag gtgcacacgc agaagtcaaa atcgtggcaa tcagctcggg cagacaaatc
    33121 caaggaatcg atacacgagt aaccaataaa gcccctcata cgatcgggca tattttgcaa
    33181 cacggagtga tccgagaaaa aggaacattg acctttaatg gtatcggcca catcttgaaa
    33241 ggggcaaaag gtgcagatgc ccaacaagaa agtcgtgtct tgatgctttc tgataaagca
    33301 cgtggtgatg cgaatcctat tcttttgatc gatgaaaacg aagtaactgc tggacatgct
    33361 gccagtgtag gacgagttga tccagaagaa atgtactatc tgatgagtag aggattgcat
    33421 aaagaagaag cagagcgctt agtgattcga ggattcctcg gttctgtctt aacagcaatc
    33481 cctgtagaac aagttcggaa agaattagtc gaagtaatcg aagggaagtt gaatggatga
    33541 tcgatgctaa aaagctacgc aatgattttc ctatcttatt tcaagacgtc aatgatgaac
    33601 ctttagttta tctggataat gcagcgacga cccaaaagcc aaaacaagta ctccaggcat
    33661 tagcgtacta ttacgaacac gataacgcca atgttcatcg cggtgtccat acgttagcag
    33721 aacgcgcgac ccatgattat gaacaagcaa gagaaaaagt acgggcgttc atccatgcaa
    33781 aagaaacagc agaagtgctg tttactcgtg gtacgacgac aagcttgaat tgggtagcca
    33841 gaaccttcgg cgaccgctat atcaaagcag gagacgagat agtgctctct tacatggaac
    33901 atcattctaa tgttatcccg tggcagcagt tggcaaaacg aacaggtgct gtcttgaaat
    33961 atatcgaact aacagaagaa ggcttcctgg atatggagga tgcagcgaaa aagattacgg
    34021 acaaaaccaa aatcgtctcc attgctcatg tatccaatgt cttaggtgtc ttcaatcctg
    34081 ttcaagaatt agctgaactt gtccatgaaa acggcggggt catcgtagta gatggtgctc
    34141 aatctgcccc gcacatggcc attgatgtcc aagcactaga ctgtgatttc tttgctttca
    34201 gcggacacaa aatgtgcgga ccaacaggta ttggtgtttt atatggtaaa cgaaaatggt
    34261 tagaagaaat ggaacctgtt gaatttggtg gcgaaatgat cgattttgtc gaattatacg
    34321 acagtacatg gaaagaacta ccttggaaat tcgaagcagg gacaccaaat atcgccggcg
    34381 ctatcgcatt aggccatgca atcgattatt tgcaaaaact cggtatggac aatatccatc
    34441 gatatgaaga agaactagcc gcttatgtgt tgccaaaatt acaagcaatt gatggattga
    34501 ctgtttatgg tccacaagac ccgaattttc ggacaggagt cgttgcattc aatttggatg
    34561 ggttacatcc ccatgatgtc gcgacagctt tagacatgga aggggtagcc gtcagagcag
    34621 gtcatcattg tgcgcaaccg ctattgaagt accttgaagt atcagcgact gctcgcgcga
    34681 gcttttattt ctacaacaca acgcaagacg ccgaccgttt agttgaagca atcatggcaa
    34741 caaaggagtt tttccaacat gggactatct aaattagaca atttataccg tcaagtgatc
    34801 ttggatcatt cttcccatcc gcatcatcgt ggaagcttga ctgactcgac aagcaagatc
    34861 gaattgaaca accccacatg tggagatgtg atcgaattgc aagtcgatgt aaaagacgga
    34921 atcatcaaaa atatcgcctt tgacggcagt ggctgctcca tcagtacggc aagtgcctcg
    34981 atgatgacag acgccgtcat cggaaaatca atagaagaag cagaacattt aactgtagac
    35041 tttctacagc ttgtccaagg aaaagaagtc aaagatcccg accaattagg cgatgctgct
    35101 atgcttggtg gtgtagctaa atttcccgct cggatcaaat gtgcgacact tgcctggaaa
    35161 gcactaggaa aagcaatgga aaacgatggt accgcagctt tccatcatta ccacaaggaa
    35221 gaggagtgag aacatgggcg taccagaatt agaagaatat aaattcgggt ttcacgatga
    35281 tgtcgaaccg gttttcagta caggagaagg cttgacagaa gaagtgatcc gtgagatgtc
    35341 aagaatcaaa ggcgaaccag aatggatgct tgaattccgt ctgaaatctc tagaaacatt
    35401 taacaaaatg ccaatgcaaa catggggccc cgacctttca gacatcgatt tcgatgccat
    35461 caaatattac caaaaaccaa gtgacaaacc cgctcgtgac tgggaagacg taccagaaaa
    35521 aatcaaagat acatttgaaa agattggtat accagaagct gaacgagctt atctagccgg
    35581 tgcttccgca caatatgaat cagaagtcgt gtaccataat atgaaagatg aattcgaaaa
    35641 gttaggaatc gtctttactg acactgactc tgctttgaaa gaataccctg aattattcaa
    35701 agagtacttt tcaaaacttg taccgccaac cgacaacaaa ttagcagcgc tgaattcagc
    35761 cgtatggtca ggtgggacct ttatttacgt gccaaaaggc gtcaaagtcg atgttccatt
    35821 acaaacgtac ttccggatca atgcggaaaa cacggggcaa ttcgaacgta cgctgatcat
    35881 tgttgacgaa ggagcaagca tccactatgt cgaaggttgt acggcaccta cttattcaag
    35941 taacagcctg catgccgcca tcgtagaaat ctttacaaga aaagatgcgt attgccgtta
    36001 cacaacgatc caaaactggt cagacaatgt gtacaactta gtaaccaaac gagcaaaagc
    36061 atacgaaggc gcaaccgttg aatggatcga cggaaaccta ggtgcaaaaa caacgatgaa
    36121 atacccaagt gtttacttag atggaaaagg tgcacgaggc accatgctct ccatcgcctt
    36181 tgcaggagca aaccaaatcc aagatacggg tgcaaaaatg atccacaatg caccaaatac
    36241 atctagctct atcgtctcta aatcaatttc aaaagacggc ggagaagtaa actatcgagg
    36301 acaagtaacc tttgccaaaa acagtgcggg ttcgatctct catatcgaat gtgacacgat
    36361 catcatggac gaatggtcga aatccgatac gatcccattc aatgagatcc acaacagcca
    36421 agtctcttta gaacacgaag ccaaagtctc aaaaatctca gaagaacaac tctactatct
    36481 gatgagccga ggcctgaccg aatctgaagc aactgaaatg atcgtcatgg gctttgttga
    36541 accattcacc aaagaacttc caatggaata tgcagtcgaa ctcaatcgat tgatcagtta
    36601 tgagatggaa ggcagtgttg ggtaaacctg ttataggagc tagaaccctt gatatataag
    36661 ggttctagct tttttgtttt gcctgtatac tagaaatgac cagattttga ccagctcttt
    36721 tactgatgag ccatcatatc agcaaagtct tgacctgttt tcttaggtgc attatttgta
    36781 atatgtgcat agatgtctaa tgtcacttta ctattttcat gccctaatcg ttgttgaact
    36841 accttgacag attctcctgc ttctaataat aaactagcat gtgtatgtct aaacccatga
    36901 ggtgtaatac gaggcaagtt atattttttc aaaatatatc ttaaccaatc attaacagtg
    36961 tttggaatgt atagagtgtt tttaactgtt gtaaaaacat gttgctcttt agagctagta
    37021 ttgtatccaa gttttaaata ctcttctttt tgctgtaatt tccagttgtt gaggatagaa
    37081 agagtctcag tatctaaaga gataactcgt ctagaagctc ttgttttcgg agattgaatt
    37141 ataactttac caaattcatc tacagcaaga gttttattga catgtagttc tttattaaac
    37201 gtgtctatgt ctttccactg taaagcgagt acttcactct ttctcatacc tgtgtatgcc
    37261 aataatctga agaaggcgta ttgtttcatg ttaccaaaat ctttaaaagc atccagtaaa
    37321 ttattaagct cctcttttga gtaaaattta cgatttttct catactcttt ttttcgtgga
    37381 agaagtgttt tttccatagg attattgtca atatattgca ttgcaacccc gtagcgtaaa
    37441 atttgtgcag tctgttttct catataatcg taactttcat atttactgtg ccattcatct
    37501 accacttttt gacaatatgg gacagagata ttcgatagtt taagcttacc aaatgctgga
    37561 agtatttgat tatttgcgta tcttactgag attgcgattg ttgaagcttt aacactggta
    37621 cgctgatgag ttatccattc attatacagg tcttcaaatg tcatatcagg tgctttcttt
    37681 ttaacaccgt ataatatttg atgtctgtac tcgtcataat ctttttgagc ttcttgtttg
    37741 ctactaaaac ctcttctcgt agtatttatt ttttcaccag ttcgtggatc ggtggcaatg
    37801 tgtcctttat acatccacgc cacttgaccg tttttctttt tgtactttga tatttttgcc
    37861 atgaaatcat ctcctcttag tttacaagga gtacttacca ctagatggta tcacctccct
    37921 tcattttttt cttagtgtat tttttcccaa ttgatgaaat cgtttgttct agcttgttta
    37981 tattatcagt aatttctctc acagcttctt cgggataaga catgtctttc aattgaatag
    38041 gtagccattc atctaccatt ctttctagta gttcttctat actgctagtg aggaaaagaa
    38101 tgttattgtc aaattcttct acaatagcat tgatgaataa ttcttctatt tttaagatat
    38161 tgaaaagact aattttttca tttttaactt tattacaagt cttgttagca ataaattctt
    38221 gcatctctgg ttctaatttg gaatatctat ccagccatgt atctaaatta gagtgtactg
    38281 gtgggaactg ttgacgaaga tgctggaaca ggtttttatc tggaaatgtt ataccatcta
    38341 gtacaatgct atctctataa agaataattc ccaaaatata ttcttctaca ttgccacaaa
    38401 ctaactcctc tatactcata tttcccaaat cagcaattcg ggataatcgc tctggtattg
    38461 gtaaataggt tcccttctcc cattcgtaga tagttttttt gtcaattaat tgaccgttgt
    38521 taatcataag accaaatgct ggttgtgtta attttttact ctttcttata gcttttattt
    38581 ttgttccgag tatctttttt cgttctaaat aatttattgg tggacgtttt atcatattga
    38641 ccacacctcc taaaattagt atacctcgaa aaaggggtgt tgtaaataaa ttttacaaag
    38701 atattgacac ctctttttta tcgaggtatt atgtgtatgt cgatgaactg gtaatcattt
    38761 tttgtttgat taatcggtta ataacaaaat acttttattt tgagcaaaaa atacgaagat
    38821 aattcttaga aaatttgttc aagcaatcac gaaaggaggg ggaaatatgt ctctacaaat
    38881 cattgatagc attgtttcta tacaagttga acaacaagtg aaagagataa ttacagtgct
    38941 aaagcctatg ctagaagaca ttatttctgg agtcactcta gagtatatgg actatcagca
    39001 ggcaagtgaa tatctaggtg tatcagtagg aacgattaga aaatatgttt ctcaatacgg
    39061 gttacctgtt ataaaaattg atacggtcat tagatttaaa aaatctgata ttgatagttt
    39121 catggaacgg tataaaggtt gagtaaacaa ataagactaa aacatatagt aataaagagt
    39181 ttgtttttat tatctgtatg ttttagtctt taacagaatt ttataaggag gaaacacaaa
    39241 tggaaacatc aatgattaat attccaattt atgtagataa agaaaaatta ttagagaagc
    39301 cagttacaaa aaaagaaaaa actgatgtaa gagataggtg tttagataac tatagagaag
    39361 ttacaagaga tgagtttgta gagatactaa attcatcaca atcatttatt ccaagcaaga
    39421 caaagaataa aggcaatgac aaggagagtt ttgtggaaac cagagtaatt attctggatg
    39481 tcgataacac tgttaaagat gagaagggga aggtagtaga tttgagtaaa gatgatagta
    39541 gatacttaag catagaaaag gttttatcta tcaatttagt tcataattct gcgtttgcga
    39601 tacaaaaaag tattcggtac tctgaaaatc tagaaaaata caagattgtc tttctattaa
    39661 aagaagcaat tactgactat ggtaaaatgg ttgctgttta cgaatacttg aaaaagaaca
    39721 tccccgggtg tgatgacaat gtaaatgctt cgaatagaat gttttttgga ggatataagt
    39781 cagatgcagt gataataatt aatgaagaca acatgttaga tattactgag cttccgattg
    39841 attttaccat gacatgttct aaaaattgtc aaagtgattc agggagagag tatgaactag
    39901 tcaatgaaac cgattttgtt aagttgataa aaaatgacga caaagaagaa atgaaacagt
    39961 ggtttaaaga ctgcctgttt gattcctccg acatgtcttt taatgagatt tatgaaagat
    40021 tgttaaccat tgatatgaat aaattactta agtcaagtaa aaacttaaga tgtctgtttc
    40081 acaacgatca taatccctct gctagtattt ttaccagtaa aactgggcat tccatttttt
    40141 attgtcattc cagtaattgt gatatcagtg aaaattttat tggagttgtg atgctaattt
    40201 taaagaaaga cagtcgggta gaaacattta attggctatt agagaaccta gacttgtatc
    40261 ctacacattt tcgaaaattg aaagaggaat caaaagtact ttttgacact cttgaatcaa
    40321 tgaaagacaa acttttcagg acaataagga attatctaga ggaaatgcga cgtgtctatg
    40381 atgtcttgct ttctgatgtt aatttttttg atgatagtaa ggaaagtgtg acttgtattt
    40441 tgtcggggga acaattagct aaaaaaatga gtttttacta tggtaaaact tatgacatag
    40501 ataaatgtaa taagttacta tcacttatga cttttatagg attgataaaa aaattagatg
    40561 atgaagatgt tcctttgaag atgctcgaat acctaaatag gttaaaggaa gagaaagcgt
    40621 taggaaactt taatcataag agaagcaatg tctatcgatt agacgttttt aatgcaactt
    40681 ctgtgattca aaaattgaat gaagatatcc ttccacttct ggaaaaattt cattttacat
    40741 atcaatattt ttcttatgaa tgggttaaga tatgttttaa cgaaaaagag gctaaaagag
    40801 tatttcctca aaattcccga tcagaactta gcaaggaaaa acaattgatt ttagatgaag
    40861 cacatgaagt tttacagggc ttatcgtggc aaggaacata tctaatgaca gagaaagaac
    40921 ttactaacac tgtttgtgaa cgtctacgta atgttgggaa taacagcgtg gaaaatgctt
    40981 taaaagaaaa cagaggctac tttgttaaac aaggattcac tcttgaacga gcttctaagg
    41041 atattaagag actatacaat gtgaaagcaa gtagtagttt tttagtctac ctagcaaaag
    41101 gagcagggat agatgaagta ataaaagaat tgatattatc aggagttgaa ttagttcctc
    41161 tttatcaatt tacaagtgta acaagagatg atggacggag agtaaggaag agaaaagacc
    41221 caattgtatt aaactagaca ggttatccat agctcttaat cttatttcat ctcaatacac
    41281 ccaccgttaa agttcggtgg gttatttatt tttcaatctt tcaatagctg attgcgttca
    41341 ttttcttgcc tttttaatag cttcatatag tcaattgttc gaactgcatc ttcagtgcta
    41401 agagaacgat agagagccaa aaactcttcc tcataatcta cgacaacatt gtctagaaaa
    41461 tggcttacag gggttcctag ggctctagaa agagcggtta agctatcgag gttaggctct
    41521 gttacagaat tttcccatct tgctactgcc tgttgtgtag agaagatttt ttcagctaat
    41581 tctttttgtg tccacccgag agcttttcgc ttttctctaa tgacctttgc atattgtttc
    41641 tgtttcatta atacaccccc atctcagtat agtacaacaa gttgttgtat ttgtaatggt
    41701 atttgaagtt tttttatatt ttatgagttg aaatacatca tattgttgta tataataaaa
    41761 caggagggga gaatcatgaa aaaagtaagt aatctcagcc gatacagaaa agaaaaagga
    41821 ctttctcaaa cggagttagc aaaaaaatga atgttacaca gcaatgtgta agttcgtggc
    41881 aaacagggag aacgattcct aaaccctatc aaatgaagat gctttctgag atattaagtg
    41941 taccaatgaa tgagctgttt tctgatgtat ttaataaagt aaacagttaa ctaataaaca
    42001 attgaatgtt tttaggagga gaagacatgt attgtagaaa atgtggcaaa gaaataacag
    42061 atgaaagtaa gtattgccag ttttgcggag cactacaaga aacagatgag acaactggag
    42121 cagacgcagt aaagaaaagt actgagcaga caattaatga aatgaaggaa caaatcgtac
    42181 atggacaaga gacagggaag ctgtatttga ttattggttg gatttctatg gtagtagcgt
    42241 tagcatttat tcctgttgta tttggtgctg ttgctgttat tatgggctac ttatatcgag
    42301 ataaagatga acaaatgggt acgattttga tgatagcagg ggtagctgga gcaatctttg
    42361 gtgtactttt agggatgtca atgtactgat aagagggata agagcaaatt attttggaga
    42421 taggagataa aaagttgaat aaagtaaata tgaacaagaa gtttatcatt atagttatcg
    42481 ttgtcttggc tattataggt atcatttttt caaaaatgac aggtacatct ggattagaga
    42541 agtcatcgaa accattggta acacagattt tacaagaaca gtacaactta aatcgatcat
    42601 gtgatgatgt gacgattact catgaaaatg gagataacac ataccgggct aaagctatat
    42661 tagacaatgg aagtgctatc aacataaata ttgagtacta tccaaagaaa gaccgtatat
    42721 atgtggagat accatatgct gaggtgttaa tgttaaattg atttaaatgt attatgcata
    42781 ccgtccaaac aggaactccc aaaggtgtaa attcactagg gagtttttat agtttcctat
    42841 aaattaaata ctaatacagg tgacaaaaaa atattacaat gattgtcggg aatttt
//
LOCUS       DAFLWQ010000015        42431 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.016, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000015 DAFLWQ010000000
VERSION     DAFLWQ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42431
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.016"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(13..2184)
                     /gene="copB"
                     /locus_tag="L1V16_000817"
     CDS             complement(13..2184)
                     /gene="copB"
                     /locus_tag="L1V16_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HBN1275177.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(2204..4390)
                     /locus_tag="L1V16_000818"
     CDS             complement(2204..4390)
                     /locus_tag="L1V16_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBN1275178.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(4390..4599)
                     /gene="copZ"
                     /locus_tag="L1V16_000819"
     CDS             complement(4390..4599)
                     /gene="copZ"
                     /locus_tag="L1V16_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HBN1275179.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(4612..5052)
                     /locus_tag="L1V16_000820"
     CDS             complement(4612..5052)
                     /locus_tag="L1V16_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HBN1275180.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(5126..5665)
                     /locus_tag="L1V16_000821"
     CDS             complement(5126..5665)
                     /locus_tag="L1V16_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HBN1275181.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            complement(6280..7746)
                     /locus_tag="L1V16_000822"
     CDS             complement(6280..7746)
                     /locus_tag="L1V16_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1275182.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(8057..10138)
                     /gene="cadA"
                     /locus_tag="L1V16_000823"
     CDS             complement(8057..10138)
                     /gene="cadA"
                     /locus_tag="L1V16_000823"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBN1275183.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            complement(10662..11021)
                     /locus_tag="L1V16_000824"
     CDS             complement(10662..11021)
                     /locus_tag="L1V16_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBN1275184.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(11051..11392)
                     /locus_tag="L1V16_000825"
     CDS             complement(11051..11392)
                     /locus_tag="L1V16_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275185.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            complement(11389..12063)
                     /locus_tag="L1V16_000826"
     CDS             complement(11389..12063)
                     /locus_tag="L1V16_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBN1275186.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(13240..14538)
                     /gene="asnS"
                     /locus_tag="L1V16_000827"
     CDS             complement(13240..14538)
                     /gene="asnS"
                     /locus_tag="L1V16_000827"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBN1275187.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVPEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(14578..15768)
                     /locus_tag="L1V16_000828"
     CDS             complement(14578..15768)
                     /locus_tag="L1V16_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBN1275188.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(15789..16316)
                     /locus_tag="L1V16_000829"
     CDS             complement(15789..16316)
                     /locus_tag="L1V16_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HBN1275189.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(16363..19152)
                     /locus_tag="L1V16_000830"
     CDS             complement(16363..19152)
                     /locus_tag="L1V16_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBN1275190.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(19299..19499)
                     /locus_tag="L1V16_000831"
     CDS             complement(19299..19499)
                     /locus_tag="L1V16_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBN1275191.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(19952..20272)
                     /locus_tag="L1V16_000832"
     CDS             complement(19952..20272)
                     /locus_tag="L1V16_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275192.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(20775..21893)
                     /locus_tag="L1V16_000833"
     CDS             complement(20775..21893)
                     /locus_tag="L1V16_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275193.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            22364..23671
                     /locus_tag="L1V16_000834"
     CDS             22364..23671
                     /locus_tag="L1V16_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBN1275194.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            23792..24991
                     /locus_tag="L1V16_000835"
     CDS             23792..24991
                     /locus_tag="L1V16_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBN1275195.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNIFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(25018..26286)
                     /locus_tag="L1V16_000836"
     CDS             complement(25018..26286)
                     /locus_tag="L1V16_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HBN1275196.1"
                     /translation="MEKQLPSPVRILMYMLKWLVVTAILGVFMGSLSAFFLNSLTFVT
                     DIRLAHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNIAHLFRLDKAEREILVISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHAYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAVLA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAAYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRIKEKNKV"
     gene            complement(26456..27097)
                     /locus_tag="L1V16_000837"
     CDS             complement(26456..27097)
                     /locus_tag="L1V16_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HBN1275197.1"
                     /translation="MEQTMKPYQYFFIKREVEQLLNAYSSVNDSKTVQTVQALAAEKI
                     RDVLGYEPSEIDTFLTTVLDVKLTKTQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQAHTYIGWNDPGTQKKFMVYYEDGKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKK"
     gene            complement(27506..28009)
                     /locus_tag="L1V16_000838"
     CDS             complement(27506..28009)
                     /locus_tag="L1V16_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBN1275198.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(28132..28896)
                     /locus_tag="L1V16_000839"
     CDS             complement(28132..28896)
                     /locus_tag="L1V16_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBN1275199.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVIPLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            29004..29279
                     /locus_tag="L1V16_000840"
     CDS             29004..29279
                     /locus_tag="L1V16_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBN1275200.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            29839..30789
                     /gene="yidC"
                     /locus_tag="L1V16_000841"
     CDS             29839..30789
                     /gene="yidC"
                     /locus_tag="L1V16_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBN1275201.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVVIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(30835..31236)
                     /locus_tag="L1V16_000842"
     CDS             complement(30835..31236)
                     /locus_tag="L1V16_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBN1275202.1"
                     /translation="MSRQLVLISHGKFCEELKKSTEMIMGPQEDIYTLPLLPEDGTET
                     YKQKFLTVTDSLNDFVVLCDLLGGTPANIISKLIMEGQQITLYAGMNLPMVIEFINSQ
                     MIGSEPEFVRAGCESIVSVNELINGIAEEEE"
     gene            complement(31250..32059)
                     /locus_tag="L1V16_000843"
     CDS             complement(31250..32059)
                     /locus_tag="L1V16_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1275203.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKIYGDNTPELKEMMKTHTQFFNTSNFFNTIITGIDLAMEEKEGIASKETVSGLKA
                     GLMGSFAAIGDSVFAALIPTIFGALAANMATDGNPIGVFIWIFAQIVVMVFRWKQLEF
                     AYKEGISLVTTMQSRLTALTDAATLLGVFMVGALVATMINVKFSWAPTIGDVTLNMQN
                     YIDMILPKILPAGIVGGVYWLLGKKNMTPTRAIFIVLIVCVALSALGVISK"
     gene            complement(32046..32936)
                     /locus_tag="L1V16_000844"
     CDS             complement(32046..32936)
                     /locus_tag="L1V16_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1275204.1"
                     /translation="MDIQWWQILLLTLYAGYQILDELQIYSSMSAPVFAGLYAGLVMG
                     DLNAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSISLGMNPEQAIAAIAVP
                     VASLMIQLDILARFANTYFAHRIDRHVEDMNYQAIERNFLMGALPWSLSRMIPVFLAL
                     AFGGGLVENVVSVLNGNLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHLSYLILGFT
                     ITALLATLFSNVQLLGTSVASVVKDLPATFNSLPMLAVALIGLALAMISYKNDQNKDH
                     QPLASEPSHSVEGEIEDDEI"
     gene            complement(32949..33428)
                     /locus_tag="L1V16_000845"
                     /pseudo
     CDS             complement(32949..33428)
                     /locus_tag="L1V16_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632653.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
     gene            complement(33604..34545)
                     /locus_tag="L1V16_000846"
     CDS             complement(33604..34545)
                     /locus_tag="L1V16_000846"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HBN1275205.1"
                     /translation="MITTVTLNPSIDIAYTIEELNLDKVNRVETVNKTAGGKGVNVAR
                     VLNLLGEEVIATGLIGGQHGEYLKNQLDQLGIMHQFVPIKGETRDSIAILHSSRQTEL
                     LERGPFITKKEQQTFTDHFEQLLEISDIMTISGSLPQGCPLDYYKQLVALADKKGKDI
                     LLDTSGKFLLEVLEGKEKPLLIKPNLEELGELIGQRICSSIQLEKIQSLLAHPIFEGV
                     PWVVVSLGERGAVAKVAQCFYEVIIPKISVVNPVGSGDATLAGSAHALSKRQSIEEIL
                     AFSMACGMANAQQEKTGWIDPMKVTMLMKHIQVKKIK"
     gene            complement(34542..35537)
                     /gene="lacD"
                     /locus_tag="L1V16_000847"
     CDS             complement(34542..35537)
                     /gene="lacD"
                     /locus_tag="L1V16_000847"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBN1275206.1"
                     /translation="MNEEKNRAMERLSTKDGIISALAIDQRGALKKMIKSLGKEPSED
                     QISEFKELVSAELTPYASAILLDPEYGLPAAKVRAKETGLLLAYEKTGYDATTPGRLP
                     DLLADWSSLRLKEQQADAVKFLLYYDVDEAPEINHLKHVFIERLGSECEGENRPFYLE
                     LVSYDAQISDSSSPEYAKVKPHKVIEMMKEFSDPKYKVDVLKVEVPVNMNYVNGYSTG
                     EFIHSKEEAAAFFKEQSEATPLPFIFLSGGVSTELFQQTLIFAHESGSTFNGVLCGRA
                     TWKDGVKAYVENGKDGAIHWLRTNGRENIETLNKVINETATPWFNKTKSKKVKMK"
     gene            complement(35530..36726)
                     /locus_tag="L1V16_000848"
     CDS             complement(35530..36726)
                     /locus_tag="L1V16_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1275207.1"
                     /translation="MFELSKNKLKQIGAAITTQEIKQQPDLWKETIDRLMQSQENLAL
                     FFDQIKKEANGRRIRVIFTGAGTSQYIGDTLLPYLNEHGDNQFFIFHSFGTTDIVASP
                     KEFLFPNEPTLLVSFARSGNSPESVAAVQIANEQVETLFHLTITCAKEGMLAKNAQDD
                     KQNYLLLMPERANDAGFAMTGSFTCMLLSALWIFDQTAMEKKERYLEQLVKIGQDLLS
                     RDQEIQKLLPDFFERIAYLGSGSLAGATREAQLKILELTAGKVATIFDSSMGFRHGPK
                     SFLNSETLVVGFVSNQPYTRNYDLDILEEIKEDRVTANVIAIAQPGTIDFSGMTVLLE
                     DSVSKLPDAYLALAMIMTAQIIALYTSIKVANKPDTPSPTGTVNRVVKGVIIHKYETE
                     GEMTDE"
     gene            complement(36744..37472)
                     /locus_tag="L1V16_000849"
     CDS             complement(36744..37472)
                     /locus_tag="L1V16_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1275208.1"
                     /translation="MESSNKGKSLYYQLVDLLKDRIETQMTPHDKLLSERELCQHYGV
                     SRTTVRLALQELENQGYIYRRHGKGTYVSDLSDKSSNLAGAYSFTEEMREIGRVPKTV
                     ILEFRQMEANKRIAKNLNIHLGETVFKLKRLRLADEEPLMVERSYLPAKLFMGLDLPL
                     LESKPLYDVFSQDYEQQVQLADEEFYASIVQKKDAVVLRIADGAPVLHLTRITYNVKN
                     EIIEYTDSVARADQFHYKIRHIRK"
     gene            complement(37913..38887)
                     /gene="lacD"
                     /locus_tag="L1V16_000850"
     CDS             complement(37913..38887)
                     /gene="lacD"
                     /locus_tag="L1V16_000850"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBN1275209.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDAKMPGR
                     LPDLLNSWSVKRLKEVGADACKFLLYYDVDEPVEINVQKQIVIERIGSECEAEGIPFF
                     LELLSYDATIGDPSSLDYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QDTCYSQAEASAYFYEQSKVTEQPFIFLSAGVSAALFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATSIYVNK"
     gene            complement(38884..39342)
                     /locus_tag="L1V16_000851"
     CDS             complement(38884..39342)
                     /locus_tag="L1V16_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1275210.1"
                     /translation="MTIIHEENIFLQQPLDNQEEAFKFLAKQTFCLGIAHDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSLIIVTLKKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRAAKSKIEIATILTKEIGEDI"
     gene            complement(39339..40802)
                     /locus_tag="L1V16_000852"
     CDS             complement(39339..40802)
                     /locus_tag="L1V16_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1275211.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFVGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAISGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSSDPDHAQYNATAAMVKAVDDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLIILPKQLDGLKAIVLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEYSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLTQGN
                     TTFMAGASAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKRDNKATNRTVIEEGRAGGLS"
     gene            complement(40784..41716)
                     /gene="pfkB"
                     /locus_tag="L1V16_000853"
     CDS             complement(40784..41716)
                     /gene="pfkB"
                     /locus_tag="L1V16_000853"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBN1275212.1"
                     /translation="MSIYTCTMNLAIDLFIETDEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPEIPQTAVHNFLNQIRALQAGDYLCVSGSLPRGLSPKVLIEISRICLIIDS
                     SDQEVMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVESGAENVLLSLGE
                     KGAILFTKDRVIRGNSPKGKVVNTACAGDAMLGTFLAGYMNRRSLDETLRKSIAAGSS
                     TAFRKGLTDFLDVEELSKQIKIKEERFERWENIN"
     gene            41858..>42431
                     /locus_tag="L1V16_000854"
     CDS             41858..>42431
                     /locus_tag="L1V16_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1275213.1"
                     /translation="MNHKLSETEQYLWNFIEHLILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGEKTNKNIKNKIYVFIFQFF"
BASE COUNT        12215 a         9180 c         7251 g        13785 t
ORIGIN      
        1 cttttttcat tattatttga ttttcaatgt caaagcattt agagctacaa ctaccgtact
       61 taacgacatc aagacagcac caactgctgg acttaatatg ataccaattg gcgcaagaat
      121 tccggctgct agcggaattg caagaatatt gtaacctgcc ccccaccaga ggttctggat
      181 cattttcttt cgcgtttgct tggctagatc aagaaaatgc aaaatatctt ttggatcgct
      241 gtttgtcaat acgacatccg cagaatcgat tgcgatatct gtccctgcac cgattgccat
      301 cccgattgaa gcacgggcta aacttggcgc atcattgatc ccatcaccca ccatgattac
      361 ttttttccct tggtcaaggt atttctggac aacagcttct ttatcatctg gtaataaacc
      421 gccataatat tcttcgatcc ctaaataatc tgctactgct tgggcagcgt ttttattgtc
      481 accagtaagc atgacaggag tgatttttct ttctttcaat gttcggataa attcttttgc
      541 ttctgttttt actacgtcac ctaaagcaac gattgcagct agatgatttt ctaaaatcag
      601 gaagctgatg gtatttcctt gttcttggta aggtttcaat aatgcttgtt ctacgtttaa
      661 tccgagacgc tcaacttctt tttcattaac tattttcact tgttgttttt tgactgttgc
      721 ctctagcccg actcctgaaa gattttttag attttcagct tgataaggct tgatttcatg
      781 ttctttcaaa taattcataa tgccaacagc caatggatga ttggcattcg cttccaaggc
      841 tcctagatat tgaaggattt catttttatt gaacgcatca tcaagtactt cgacacccgt
      901 tacagtaaat tttccttctg ttagtgttcc tgttttgtcc agcatgatca catctagatc
      961 attggcttgc tccagtgcat tgcggttttt caaaagtaat ccgtttttag ctgctattga
     1021 tgtggagcga gcaacaacta atgggatagc taaacctaga gcatgaggac aggcgatgat
     1081 aaagactgtt accatacgtt ctaatgcatt aggaagatct gtcaagaaca accaggcgat
     1141 gaatgccagg atacccacaa ttaatgcgac ataaaacagc cattttgcca ctttgtcaga
     1201 taatgactct agcttggatt tttctccttg tgcttttcgc accatttcca taaccttcgc
     1261 tagataacca ttttcaccag ttccagttac ttcgatttcg atcgttccat ccccattgat
     1321 agaaccgcca atcactttgt cattggcttg ttttttgatt cctcttgatt cgccagtcac
     1381 agctgattcg tcaacaattg tttcaccttt caagattaca ccatctgttg gcattttatc
     1441 accagaccgg acgatcaaac gatcaccttc gtttacttct ttcaatgaaa ctgtctcttc
     1501 ttttccatct ttcgtcaagc gtttcactga ttctggcagt aattctgcta gtttttgtaa
     1561 agcattgctg gcattcgaca cagcattcat ttcaatccag tgacctagta gcataataac
     1621 gatcaaagta gccaattccc agaagaaatc catgacgtgt gtatgtggat tgagcagatt
     1681 tgcgataaac gaatagacac tataaatata tgcaactgta atccccatcg cgatcagtgt
     1741 catcatagca ggactttttt gtttcaattc catcttagct ccacttaaaa atggctgacc
     1801 gccatagata aatagtatag ttgctaagat caatacgagc caatcagaac caggaaacgt
     1861 tacttgaaat ggaaattcca ttcccatcat tggtgaaaaa agaatgattg ggatagctag
     1921 gataagcgat agccaaaatt tttgtttgaa attccccatg tgcatggaat gatccatgcc
     1981 gccgtgttcg tgatccatgt gcatcgaatg gtccatttgt ttgctgtttg ctatatctcc
     2041 atggttatgt cccatgtgca tggaatgatc catctgacta tggtcatgtt tcatctccat
     2101 ctgtttttca tgagattctg tactttcttt gtttactact tcttttttat gctcatgttt
     2161 tttctccata tcgttcccat tcatttttac tccatccctt ctcttacttt ttcatgtgtc
     2221 gatttaagct cagggagttc aacaatacac tgacggaact aaacgccatc gctcctcctg
     2281 caatgattgg attcaaaaag cctagtgcgg caaaaggaat accaatcgta ttatagacaa
     2341 aagcccagaa aagattttgt ttgatttttc tcaatgtcaa cctagacaac tcgattgttt
     2401 gtgcaatgga tgccaaactg ctattcatca gcgtcacatc ggctgtttcc atcgcaatgt
     2461 ccgttccact tcccattgcc ataccgacat cagctaatgc taaggccggt gcatcattga
     2521 ttccatcgcc tgccataccg acttttttgc catctttctg aagtttttct acgtaggctg
     2581 ctttatcctc tggaagtact tcagcaaaga tatgctttgg atcaatacca acttgtttac
     2641 caatcgtttc ggctgccagt ttgttgtctc ctgtcagcat aaaaacatct aatcctttat
     2701 tctggagctg cttgattgct tgtttggctt ctagtttgat ttgatcagcc acggcaatcc
     2761 acccgatcac ttgcttttca tcagctaaaa acatgactgt ttttccctgc tgttctaatt
     2821 ctaacgcgtg ttcttggtat tcatcaaatg ataggttcaa ttcaattaat cgtttacgtg
     2881 tacccgcaaa atagcgtact ccattaatcg taccgctgat cccagcacct gggtgggctg
     2941 taaaatcaat catatcgtat gttgctgctt cttgcagttt tccgtattcc acgattgctt
     3001 tacctagtgg atgttcagaa gcttgttcta aagtataaaa aatagatagg acttcttttg
     3061 aaccgactag atctgtaact ttgggctttc cttctgtaat cgttccagtt ttatccaaaa
     3121 caatgctgtc taagtgagca gctgcttcta atgcttctcc gcctttaatt aaaattccat
     3181 ttcgtgcacc aacacccgtt cctaccataa tagctgttgg ggtcgctaaa cctaatgcac
     3241 atggacacgc aatgactaat acagagacac tatggatcaa tgcgagttgc caatcaccag
     3301 tgatcaaacc tgtagctatg agcgtgataa acgcgatgac taatacgatc ggaacaaaaa
     3361 tccctgagat ccgatctgcg attttttgga ttggggcttt gctcccttga gcatcttcca
     3421 ccatttgaat gatttgcgct aatactgtct gcttgccgac ttgtgtgact tccatgtgta
     3481 gcagaccatt cgtattgatt gtcccgccaa aaagcgtgtc atccggattc ttttctacag
     3541 gaagattttc accagtaagc atactttcat ctatcgcact gcttcctgaa ataattcgac
     3601 catctgctgg aatctgctca ccaggacgga tgactagttg atcaccaacg actacttctt
     3661 caatcgctaa cgtttcttct ttcccgtttc ttatcacttg ggcggttttt gtttgaagag
     3721 acatcaattg tttgattgca ttacctgttt tcgtttttgc tgtatgttcc aaatatttgc
     3781 cgagcaaaat cagcgtgatg atcatactgc tgctttcaaa ataaagatct tgggggtgtc
     3841 cacggaaaaa tccgttgtaa atgctcaatg caaaggcagc cgatgttcca attgctacca
     3901 atacatccat atttggtgct ttcgtcttga ttgcatggta cgcaccttta taaaaacgag
     3961 caccgacata aaattggaca ggagcagaca gcactaactg gacgattgga aaatgaaaaa
     4021 agtgaacaat cgccgcatgg cttcctaaca tcatagcaat cattgacaac atcaacggca
     4081 aagtcaaaac cgtactcaat ataagatcga atagcatttt tttcaaatac gcttgctttt
     4141 cttctgcaat tttttgtttg tgggcttcat cgtacaaaat tgcaccataa ccgatgtttt
     4201 ctacgctttg gattaatttt tcagtggtcg tcccttcata tttgacactt gctttttcag
     4261 tggccaagtt gactgtggca ttgaccacac caggttgtcc gttcagctct ttttcgatcc
     4321 tagcagaaca atttgcacaa gtcatacctg taatgacgaa cgtatccatt ttggtttctg
     4381 ctgttgccat caaatcacct ctgctttata acccaatcca ttgattgctt gacaaatctt
     4441 ttcggattga acttttgttt catcaaactt gaccgtaccg tttgcttttt tcaaatttac
     4501 tttcactttt tgcacgccgt caagtgcgct tactgtttct tctactcttg ctgcacaatg
     4561 attgcagctc ataccttcga ttgaaaattg ttgtttcatt ttttcttcct cctattgatg
     4621 ttgtttacat tcacattgac ctgggataca gttacattcg atcgtatcta ctggttgctt
     4681 ttgttccagt tgtttcaaaa tctcattgat atcttcttga gtcaaagtgg cttcttctac
     4741 tagatccgca atcgtctctc caatcctttt tgcacagata tgggaaaaaa gattttccgt
     4801 cgcactgcga actgtttcca tctccgagac agctggatga taaatgaatt tttttccttc
     4861 ttgttctgtc cagatcactt ctttttttac caaacgtccc agcaaagttt tgatcgttgc
     4921 tggtttccaa tccatcgaat cagctaagat ctgcgtgatt tcttgggctg tcgtctgtcc
     4981 aagtgtccaa ataacacgca tgatctccca ctctgaatca ctgatcttta ctggcgtttt
     5041 gactttttcc atttatttca cacctttcgt ttacaaatgt aatcattagc ttatgaatac
     5101 agattacgct tgtaaacaaa aactgtcaat tatttttgct ctctattttc aatttagtta
     5161 aaaattcttg tttctctcgt cttgttttaa ggatgatcag tttatttctt gcattagcta
     5221 cttggatcag ctgctgtatt ttcggttcat tgttttcttc aaaatgccag ataaaagata
     5281 aaaattctaa gtattccctg tttagtttct ctgaaaatga ttcaggcata tctggccgag
     5341 attttttgtt tatctttctt tttagagaac gccaaactac tcggtagatg gcgagataac
     5401 gcggcacttt aagccaaatg atcttatctg cttctttaat cctttcctct aatgtagaag
     5461 tataatttcc ttcaacaatc catgacggat tagataccat aaacgattgc tgttcttgca
     5521 aaaaccactt ttttgcctga atactgtagt ctgttgtatg ccataaaagg tctagcggca
     5581 gtagcggaaa gtcggtgatt tctttgatct tccttgcgag ggtcgatttt cccgacccac
     5641 tttgtccaat cacgatgatc ttcattcttc tccctcactt ctctttggaa tttggttcga
     5701 tcataccact tataacgccg caaaaaaaca agggactgtg acaaaagtcg tgtcaaagtc
     5761 ccttgtttcg aataaatggt gttcaatcag ctgaccttca gcattaactc aaaaaacggc
     5821 aaaatatgag gagctatttt ttcgtttgtt cctctaatac tcaggtcaaa tcgctgattt
     5881 tacaacctct tccttaaacg gtgttctcct gccaacacct cggtcacaag gcacaatagt
     5941 caacaaacat gagaagttgt tttttgaaat tgctccttgt gactcggagt taaacggcag
     6001 gctcactacc tctttcttaa acggtgttca aaagcttgca tctgcggtaa taagcccagc
     6061 aaaacgaaaa atatgagggg ctatttttgt ttggctgttc ttattacttg atgcaggaca
     6121 gctttttcac aacctctgat tcacggtgtt ccagaagtag cttctgcgaa aaacaagccg
     6181 aaacttcaca aaaatttgag aagcaatttt cgtaaattcc ttcttatttc ttgaagctga
     6241 ccacttctgt cacaacctct tgtaacaagt atttctattt taaggctgaa ccactgtttc
     6301 tggttcagtg atttctttgt ttttgtctcg acgagcaatt gctggcaaga tcatacctaa
     6361 taagatcaag acaattggtg tgatgatatt cgtgaataat tggaaccacc atgctttagg
     6421 atcagcagta taatctactt ttggcaccat tcctaggata catgcaaacg cagtgaaggc
     6481 aaagcaccaa gcaccaaaga taaaaccgat ttttggattt ttaacaaatt tatattcaga
     6541 attgaatttc ttataagctt tattcaacat catatatgcc aagaacaccc ataggtaacg
     6601 cattggcatg acaactgagt tcaagttcgt caaccatttt actaattcat tcatatcttt
     6661 gataccaaag atcggcaaca aaataatgat tcctactagt atacctgtca gaagataacc
     6721 attcaccaat gtacctttac gattacgttt acgtagccag tttggtacaa attctggatc
     6781 cgcatctgct aacaagattt ttagtggtgc atcaattgaa aaggctaatg cggagatttg
     6841 tccaatcatg tttgtcaatg cgtaaatgat catcaatgag ttaccgatac catagtaatt
     6901 acctaaaatt tgaaaagcac tgtatgcccc atttgccatc aagtctttag gaatattatc
     6961 gctagcaaac agcataccca ttgcgactga gcctaataca gcacaaatcc ctaccattgc
     7021 tgctaagaag atcatccctt taggaaattc ctttgcagga tttcttgtag agttgacata
     7081 aggggatatt ttttccgctc ctccaactgc aaatactagc atcgaaacgg ttgtgaaata
     7141 actgaaatca aatgttggaa tatatgtttt cacttgattc atatgtggtg tggcaaattc
     7201 catcgttgga ttgatgaacg gtgccgttac agctaaaaga ataaataaga tcgacatgac
     7261 gaacatcgct gttccggcca gtccgccaat cactttcaaa gtagaaagtc cttttgttga
     7321 taaatataaa aaggcaagaa atataataag tgaaataact gctaccattt gtactgacat
     7381 cgtatttacg atatttccat ttccttggac tgcccaaccg ccagcaatca ggattgcttg
     7441 aggcttttgt gccaaataag gaatatggac gacccagtaa gtccaagcgg catagtatgc
     7501 cagtcgttta ttagatgtcg tattttcgac ccatgaactg acgcctcctt tactatcctt
     7561 gaaggctgac cctaattgtc caacgatcaa tgcgtatgga ataaaataaa tggccaaaat
     7621 caatagccaa gaggtgacaa ctgatactcc ttgctgagca tagttattaa ctacattccc
     7681 catgccccaa accatgttaa atgcaattaa cgcaacagta aaccagcgta attgtttgtt
     7741 gttcattcgt tctctccttt atgataaaaa tttgttatcc agatgtaatc atattcaatt
     7801 tttaacaaac ttacaagaca gtgttatttt atgtgtgtat tcttttattt aatacacatc
     7861 gttttttcat attttttcca tcaaaaaaat aagttatttt cttttatttc atttacctta
     7921 ttgaatttca agctattttg aattttctgc aaaattaaaa acattagtta ttttataatc
     7981 ctatctattt tctttacatt tttcattaag aaaaggatat aaaaaaaaga ggacgttcat
     8041 tcgtcctctt cattgatcaa cgtttatttt ttacatgcaa gcttcgcatg gcattcaaaa
     8101 cagctaatac tgtcacccca acatctgcaa atactgcatc tcccattgat gcaaaaccaa
     8161 aagcacctaa ggcaagtacc aaaattttta tcccaatagc aaagacaatg ttctgtttga
     8221 cgattttcaa tgttttcttt gctaaatgga ttgcttctgc aatcttcgat ggttgatcat
     8281 tcatgatgac tacatctgct gcttcaattg cagcatcgct tcccaatcca cccattgcga
     8341 ttcctacatc tgctcttgct agcaccggtg catcgttgat tccatctccg acaaatgcgg
     8401 tctttttatt gtttctttgt aagatttcct ctaaccgctg cactttatct tctggaagca
     8461 attcgctata tatcttgtcc acgcctactt gcttcccgat atgatcagca atttttttcg
     8521 aatcgcccgt caacatgact gtgttcttca caccagcctt ttttaattga accaatgcgt
     8581 ctacggcatc ttctttcaag gtatctgcaa taacaagata accactgtaa ctttgatcga
     8641 tcgctagata aagcaatgta ccgatttctt gacttgaagg aaaagagatt tcaaatcttt
     8701 ccatcaattt gtgattacct gctaatactt gtttgccatc aacttcagct aagatccctt
     8761 cacctgcaaa ttcttggata ttagctgttg gtaaaagcgg acctgcgtag ccttctaaaa
     8821 cagattgagc aatcggatgt gtagaaaact gttctgcact cgcaacatat tgcatgaata
     8881 tctttggatc gatttttgta tcgatcgtct ggatcgaaaa gtcacctttc gttaatgtgc
     8941 cggttttatc gaataccact gtctcagttt gtgcaagcaa ctccaagtaa tttgaacctt
     9001 ttactaatac accgatttta cttgctcctc cgataccgcc aaagaaacta aggggtacgg
     9061 agatcactaa tgcacatgga catgagatca ctaaaaatgt caatgctcga tagatccatt
     9121 cagaaaacgc cgctccagaa acaacaagtg gaggtaaaac agctaataaa acggccaatc
     9181 ctacaacgac tggtgtgtaa tagcgcgcga atttagtaat gaaattttca gctggtgctt
     9241 ttttactgct ggcattttct actaattcta ataatttgct gatagtagaa ttttcataag
     9301 atttttctac ttgaactaaa aatggtttat ttttattgat aaatccactt aatactgttt
     9361 caccaacata tacagattta gggactgatt ctcctgtaag tgctgacgta tcgactaatg
     9421 attctccttc gatgatcgtt ccatctaacg gtacacgttc accaggcttc acaagtacaa
     9481 actgaccgat ctgcacgtct tcagggttca cggtcatcaa tccttccgtc gtctgcacgt
     9541 gagctgtttc tggacggatc gccatcaatt cgcgaatcga ttttcttgaa tgactgactg
     9601 ccaatccttg gaaatactcg ccgatttgat aaaatagcat cactgctacg gcttctggat
     9661 attcaccgat caacatagcg ccaatcgtag caacagacat aagaaaattc tcatcaaaga
     9721 tttttccttt gacgatattc atcactgcct tcttcactac atcatatcct atcagcagat
     9781 aaatcaataa ataccctatc aagcgaattg gttcattaaa atcaaataat agcaataaag
     9841 cgatacctgc aagggaaaat aaaatccgga acagcgtatt tctctctttt tcatttccat
     9901 gttcagatac tttttcctta tctatttctg ttactttgac atctggttct aattccttca
     9961 ctactttttt tatttcttgt tcaatcgtag ccaaatgatc ttcctctgcg tcaatcgtta
    10021 gttttccaga agtgaagttt accgttgctt ccttgactcc attgatcttc tgaactcctt
    10081 tttcgatttt cattgcacag ttcgcacaat ctaaaccttc taatctgtaa cttttcattt
    10141 taatgacctc ctcgcctcaa catatgaata tctcttcata actaattata aatgaacggt
    10201 tattcatatg tcaaggtatc cgaaagaaaa aatgaaaaac atctgcatcg gaaaatttct
    10261 tccatacaga tgttttggct tattctttct ttttcttttc gatcattgcc actgctctta
    10321 tccaacccgc acttgccttc ttgatcttga caggatagca actaagtttg aagcctgttg
    10381 ctggcaattt gtctaaattc attaattttt cgataggaca atatcttttt tcaatccctg
    10441 caaaatgtcc ttcccagata ttcgaagctc cactacgctt tcaaaaatat agaaagagtt
    10501 ctttaatgaa aattatttca actttccata aacagtaacc ccatataaat aaaagacgta
    10561 aaagtcacat ggaagaactt atacaggaga acgcatagag tcaggtgaaa tacatgtatc
    10621 ccacctgact ctatgcttta tctaaccttt attattctct tttatacaat ttctgcaccg
    10681 aatggcatca acgccaatcg agcaagtttg aaagattgct tggcaaaagg tatccctatg
    10741 atcgtgatac atagaaggat gccgctgacg acatgtgcga gagcaattgg taggcctgaa
    10801 acgatcagcc agatgatatt aacaatcaat gacatgccag actggtgata aattacttct
    10861 ttgccaaaag gcgcaaaaga aagggaggcg atcttaaaac attgcatacc gattgggata
    10921 cctatgatcg tgatacacca aagtatcccc gctgctaacc agctaagacc accgattagt
    10981 ccgccgaata taaaccagat gacatttcct aaacaactca ttgtatttct ccttctatta
    11041 ctgtttttga ttaaaactgg gcaaaaaatg attttattct tcttttttta gcttccagta
    11101 tcaaatattc tgcaaatttt ttttggattt cttccgtatt ttcttttgtt actaatgtgt
    11161 gttggattag ttttcctgat ggtcgctgat ccaatcgttc ttctgactgt tgcacgtccg
    11221 cttgcgcaaa tccgataatc cgtttttctt ttgttacagc aacgagcaat agtttattct
    11281 tatcatttag gtcagctgcc gtttttgctt ttacgaatga ttctggatga tcagtaatca
    11341 gctgattgat ttgaggtaga tcttctttta ctgcccaccg tatttccatc atttctcact
    11401 tttctttcgc tcatttttat ctccactaaa aaaatcgact gcggcaattg catctatcca
    11461 gctttgtgca atgatctcat gtccgccaat cgttgggtgg accccatctt ctcttgtata
    11521 tttcgaaaaa ccataaacaa tccctaaagc attgaatata ccatctaaag gaaccagcaa
    11581 tgcgccatat tccttagcaa gtttacgaac aatttggatt ttagggtcta agtctttacg
    11641 ccagccatga cggtcgtcgg ttataggaag tacaaacggc tccatcaaga tgatgttgca
    11701 gattcccact gtttgaagtt catttagtaa ttttcgataa acggattcaa attgctgagc
    11761 agatttctca gttccgaata tagcctgatc gctagtatta tgccaggtat cattgattcc
    11821 gatcaaaatc gatacatagt caggttgtaa agctaaacaa tcttcttgcc agcgtacttg
    11881 cagatctgca attttgtctc ctcctatccc acggttcatg cattcaaatt ccatcgttgg
    11941 atattgggag attagttttc cggcaatcaa aagtggataa cctttaccta gatcagttgc
    12001 ttctgctcgg tctcttcctg cgtctgtaat gctatcaccg ataaataata tacgtttttt
    12061 catttgtcaa aaactccttt ttgaataaaa cgatgatttt cttccttata ttatcccata
    12121 agccctatca agacgaaaga gaaaatatat gtataaaaaa tgacaccagc ctagtccctt
    12181 caaacaattg aatgaacgct catcaagtgt ctagtttttt atgctatttt tttcttaacg
    12241 tgccggattc cccttgattc cttcgttgtt tggtccagag agatcgatca cacctaagct
    12301 tccgtcaatc agaccactga tgacgccatc agaacatata tttataggct catctaagac
    12361 ttctagtaaa tgtcccttta ctaatatctc ttctagattg cttgggatag attggtcata
    12421 actttatctg gtccgatgat ttcaagggtg aattgaactt acatatggat tattgcatgc
    12481 tgaaaatacg gacctactcc atcttcgaat gttactatta gtttgttttc aggtgctaga
    12541 tgctgcttta tttcaacagc agaagcatca tcaaatcaga tttccatttg aattaccttc
    12601 tttgtaaatg tttgattgat tgcgatttcg ttatagaacc ttgtgaatca aatagcaatt
    12661 tcttttgctt tcttctcttg tctgctggaa acttccttta tcccgtattt taaaaaaaga
    12721 actgcgagag ttcgcagttc ttttttagaa taaacggtgc tctccggcca actcctcggt
    12781 cacaagtcac aatagtcatc aaacatgaaa aactgttttt tgaaattact ccttgtgact
    12841 cggagctgaa cggcaggcgc acaacctctt gatataaacg gtgttcaatc agctgaccct
    12901 cgatattagc taaaaaaacg gtaaaatatg agaagctatt tttccgtttt gtttctctaa
    12961 tactcaggtc aaggcactga tttcacaacc tcttccttaa acggtgttca aaagccagtt
    13021 tctcggtatt aagccaaatt tatgcaaaaa tgtggaaagc catttccaca aaatttttct
    13081 taatactcga aactaaacag ctttttcaca acctctccac taaacggtat tcaaaagctt
    13141 acatctgcgg taataagtcc cgccaattca aaaacatgaa cagctgtttt tgcttggctg
    13201 ttctaattac ttgatgcaga acagcttttt catcacctct tatggataaa ttcggttcaa
    13261 caaacgtggg aatggaatag cttcacgcac atggtcgata ccagcaatcc aagtgactgt
    13321 tcgttcaagg cctagaccaa aaccagagtg cggaacagaa ccgtatttac gtagatcaag
    13381 ataccatgaa tattcttttt catccaaacc gtgattacgg atttgttcta gcaagaaatc
    13441 atagtccgtt gcccgttcgc ttccgccaat aatttcaccg taaccttctg gtgcgatcat
    13501 atctgcacaa attaccacgt cttctcttgt tggatgtggt ttcatgtaga atggcttgat
    13561 agcttttgga tagtttagga taaagacagg ctgttcgaat gaattcgcaa tgaacgtttc
    13621 atgaggtgaa ccaaagtctt cgccccattc gatgtcatca aatccatttt tcttcagtaa
    13681 ttcgatcgca tcatcataag taatacgagg gaatggcaat tttgtataag tttttaagac
    13741 ttctttgtct cgtcctagta catctaatgc gtattcgcaa tgatctaaaa cattttgtac
    13801 taagaatgct acatattgtt cctgtacttc taaactttct tcttgatgag tgaaagccat
    13861 ttctggttcg atcatccaga attcaatcaa atgacgtcgt gtttttgatt tttcagcacg
    13921 gaaagtcgga ccgaatgaaa agacttttcc gaaagccata gcagcagctt ccatgtataa
    13981 ttggccactt tgagataaat aagctttttg atcaaagtaa tttgtttcga atagatccgt
    14041 agtgccttct ggtgcggaac cagtcaagat cggcggatcg attttgacaa aatgatgttg
    14101 attaaagaat tcatacgttg cacgaatgat ttcatttctg atctgcataa tcgcatgttg
    14161 tcttgaagaa cgtagccata aatgacgatg atccatcaag aagtctgttc cgtgttcttt
    14221 tggtgtgatc ggataatcgt ggctctcgct taccacttcc acatttgtaa ttccgatttc
    14281 ataaccaaat tttgaacggc tgtcttcacg gatttctcca gttactaaca cggatgtttc
    14341 ttggtgcaga tttttagctg tttggaaaac ttcttccggc acttcgcttt ttacaactac
    14401 accttggaaa aaggctgttc cgtctcttaa ttgtaaaaat gcgatttttc cgcttgatcg
    14461 cttatttgcg acccaagcgc cgattgttac tgtttctccc acatggtttt tcgaatcgat
    14521 gatttgaatt tgttccacgt atgactctcc ttttatattc cttgaatttc ttcaggatta
    14581 attttgactt ttactctcaa taaattgctt gattctgcgt accgcttctt ctaacgtagc
    14641 gcgatcagtg gcataactca tgcggacatt ttctggtgcc ccaaagcctt cgccagtcac
    14701 aagcgctacc cctgtttctt ctaaaagatc ttctacccat tgtgtgacat tttcatactt
    14761 acacatgcgt agcgtttctt ttacattagg aaaaagatag aaagctcctt gcggcttttc
    14821 aagagaaaca cccggcagtt ctgccacaag cggatataac gtattcaggc gttcttcaaa
    14881 ggcgttccgc atttcttcta ctgtatcttg ctcacctttc aatgcttcaa cagctgcata
    14941 ttgactgact gctgtcggat tgctagttga ttgggaagca acagcgatca ttccattgat
    15001 gatcacagga tttcccaccg cataaccaat gcgccagcct gtcatcgcat atgttttaga
    15061 cacgccgttg atgatgatgg tctgattttt gattgcttct gaaatcgttg caattggagt
    15121 aaactcattg ccattataaa ctaaacggcc ataaatatca tcagcaacta tcaaaatatc
    15181 attttttact gcccattcac cgattgcctg cagttcattc ttgctataaa tcattccagt
    15241 cggattcgat ggagaattga tgattacggc ttttgttttt tctgaacgtg cttgttctag
    15301 ctgttcaaca gtaactttcc agctattgga ttcttcccct ttcacaaaga caggaagtcc
    15361 ttctgccagt tttacttgct caccgtaact gacccagtaa ggcacaggaa tgatgacttc
    15421 atcttgcggg tcaaggatcg tttggaaaag ggtatacaaa gcaaatttcg ctccgtctgt
    15481 tacgactgtt tgtgaaggtt catagacaag tccatagttt ttcttcagat aatcaacgat
    15541 tgcctgtcga agctctggga ttcctgctgt tggtgtataa tagctagctt tcccattgcg
    15601 gattgcttcg attgctgctt cttggatgtt ttctggtgtc gcaaaatccg gttctcccac
    15661 agtcaaactc agcacatctc tgccttttgc ttttaatgcc ttggcctttg ccgcagctgc
    15721 caaagtgaca gacggttcta atcgttttgt tctttttgat aactccatcc cattcattcc
    15781 tttacctttt aaattccctt gattgtcttg acttcatctc cagattcaaa gccaatcagg
    15841 taataattca gtttcccatt tgtttctttt cctactactt cccacacagg ctgatcatca
    15901 tacatcccta aagcagcttt ttcgatttgg atttcaggat gggccgcagc aattgtctgt
    15961 tttgcttcgt tttcagtcag tccctttgtt tgatccaata cttttacttt ttcaccagat
    16021 ttaggaatga taacggcgat ttcttttcct ttatcatttg tacctgtcag tgaaaagtat
    16081 gtcttctttc gagtaaacca ataaaaatga tcggtttcct caagatttgc atatttcttt
    16141 gcgatttcta ctgcttcttt cttcgcctgc accgccggac gactggaacg caagtaaaaa
    16201 atcgagctga tcacgatgac cgctaataaa aatacgatca agccaagtaa cacgcgatta
    16261 atcgtttttt cctttgtctg ttttttcttc aagggtcgtc gctcctttat cttcattcct
    16321 tttcattata gcagatttta attatgaaaa aagacagctc ctctaacttc cttcttcatt
    16381 tttctttaag aattcatgga tatcctgata gatttcctcc atagctagct ctttgatcgg
    16441 tacttttttc ggtaatgcat ggatgatccg tgcgccatat tttgcagtga ctagtcttcg
    16501 atccaaaata agcaatacgc cacgatctgt ctccgtcctt atcaagcgac ctaatgcttg
    16561 gcgtaacttc aaagctgctt taggtacgga ttcctggtaa aaaggattga tcccctctga
    16621 ttctaaataa gcgttcctag ctttgaccat cgggcgaagc ggattatcga agggtaaacg
    16681 tgtgactaca acgatctgca aagcatctcc aggcaaatct acaccttccc aaaagctgtc
    16741 agcgccaaac aatacgcttt tttctgacaa aatgaagcgt ttcaaaagct tctcccggct
    16801 tccaccaaac ccttgagcta gtatttctcg tcctttttct agcatagaca gatgcatttt
    16861 ctgatagacc ttctgcaaaa catcatgaga agtgaataac acaagtattg gccgatcttc
    16921 ttgttcgatc agacctgtaa gtgctgtctc taaataatcg atatatgctt gattgctgac
    16981 ttgatggacg gcaggtgcct cttttggcac atagatcctt gcctgtttct cataatcata
    17041 aggagaggca atcactttaa gaggtgctgc ttcaatgcca agcctcttag agagatagtg
    17101 tcgattaggg ccgatcttca gcgttcctcc aatataaaga atacgatcat atcgaggata
    17161 ccaaacagtc gacggcaaca tagccgcttg aaaatcatgg agatgaaaaa tcatctgctg
    17221 cgctgtgttc ccaggaacga accaatggat caaatgatct cgccagtctt ccagccattg
    17281 atccatcagc aagtattgct tgtctaattg atcaaatagg ctatataaac ttgctaaatc
    17341 gatccgcatc tggtttgtcc agctttcttg gataatctca aaagtcagac gcatttgtga
    17401 ctgtagctgc tggatctcct gataaaaaag ctgcaggtga tcaatggctg tcccagattc
    17461 cagtggcagc tgatccaaca tctcttttgt catcatgact tcttctggat actgtccgtt
    17521 aggttgcttg ccgctcacta aactcattaa tccttctgcc atacaaatct gtgcttcgca
    17581 tagcgcagaa agttcttctc gataaatcga taaccagcgt aaggcttcat gttctttcgg
    17641 taaatagctt tgtattcggt caaacagctg atttggttct tctaattgct ggatttgttt
    17701 atggaaatag ttaatactta atcgtttgtc atttactttt tcagcgattt ccggcaaatg
    17761 atgtacttca tcgatcaaca aaaatggact agctggaagc aatggttctt ttcgctgtgt
    17821 ttcttgtact aaaaacgcat gattgacaat caaaaaatta ctttgcctga ttttcttttg
    17881 caagaaacga acaaagtctt gttcgtaaaa tgactgattt cttgctaaaa atccaatacc
    17941 tctgtgcgcg atatctgcaa agaatgaatg gttcaaattt gttaaatgta attcatccaa
    18001 atcaccagtc ttcgtttgcg tcagccaaac taagaccgcc atttgataca aagcatattg
    18061 tttttgttct ggcggttcca caagtgtgcc tttaaaacgc tgcaaatcaa tatagtggcg
    18121 atagcttttg ataattacag gttgtatggg ctgatctagc aattgattca gcaatggaat
    18181 gtctttttct atgatctgct gctgcaaaac tagcgaaacg gtactgatga cagcgggttt
    18241 ttcaggtgta gccaaataac tcaatggcag cagataaccg attgttttac ccattcctgt
    18301 agctgcttcg atcatcaaat cttttgattc atcttttgtg aaatggtcgt agaccgcatt
    18361 catcagtctg ttctgttctt ttcgatacat cagtgtttta ccaaacattt tttcttttgc
    18421 ttgttttttt cttggatatg tccgctcgcc ataatggacg gatgtgaata gttccacttc
    18481 ttttttctgc aaagctagcc catcgacgat ttctaatgag ggatcaagtg gctctggttt
    18541 ttctttcatt tcttcaatca catgataaat gaaacgactc gtatccatac ctgtgtgtct
    18601 acttaatcgc gcaatctgct ctaacgtgat gattggcaat tttctcatcc gttcttcgat
    18661 cagcaaaaga agttgacctg tcacttcggc atcactatct gcctgatgag gattctcatg
    18721 aataaatcca aggctttctg acaaatcagc taagcgaaag cttggttccg tcggcaagaa
    18781 aatttgtgca agttctactg tatcgatgcc tggtatcttc aaactaggaa gtccgcatcg
    18841 catgagttca tggttcaaaa aattataatc aaaataaata ttatgcgcga caaatatggt
    18901 gtctgccaaa agattgtaaa tcgtttgggc gacatcttcg aaataaggcg ctttttggac
    18961 gcgttgattc gtgatccctg ttaaatgctg gatttgtttt gaaatcttcc gccctggatg
    19021 aatatcgatc gaaaaacgtg aagtgatccg acctgattca atcatgacgc agccaaattg
    19081 gatgatccga tcttcttttg gattcgtccc agtcgtttcg atatcaacga ctgcataagt
    19141 tcttggtttc aaaatatctt cctcttctcc tgcctctaat gttcttttga aattatacta
    19201 caaagtgcag aaaaatactc tcatcgcttt ttaaagaaaa tagacaaaaa cgcccagaca
    19261 cgcaaatgtc tgggcgttta ttttttagta taggttaatt aagctttagt aacgtttgtt
    19321 gcttgaggtc cgcgttggcc ttcttcaaca tcgaaagtta ctgcttggcc ttcttctaaa
    19381 gttttgaatc cgtcgccttg gatagctgag aaatgaacga atacatcgtt tccgttttct
    19441 gcagtgatga atccaaatcc tttttctgag ttaaaccatt ttactgtacc tgtttccata
    19501 ataaaaatcc tccttgtgta tcaacacata ttttgcaatt acttgaatgg tgtatatctg
    19561 gaagatgttt atttgaaaca agctaccaca gattaccgaa caaaaactac tcctatagta
    19621 tatcataccg tttacaaaaa agctagagtt tttcgacttt ttttattaaa aaaagttttc
    19681 tcagcgatta cataaagtga aaaaccgaac ttttttttaa aataaacgac atattgttca
    19741 gttggtgttt ttttgctctg atgttctttt ttaaactaaa aaaattattc tttctgacta
    19801 cttatcggtt ctgtttcaac ggtcgaggct ggggaagatt ctttagtagg tctgatgttc
    19861 tcatggtatt tctgatagcc tatgacagtt accagaagaa caaggcaaac caatacgacc
    19921 aacgagatta gtttttcttt tttgctcata tctatacctc ataaataaca ggatgatgtc
    19981 catcatattt ctgagtatga gtaaaagcaa aagctgcagc tgtagaatgt aagaaatgcc
    20041 agcaactttc ataatcacag gtcggacagt accaaaagta accaaatctt ggctgcaaag
    20101 accgttcttc tgtttcagga atcgcagaat caagatctgg tgtctgtaca taaacatttt
    20161 tgtacagacg tgtgcctgta ataggaaacc gctgtgtttc ttcagcaaaa actggctgac
    20221 ttgttaaact tagggataga gacagcaaac accataacag tctttttttc ataaagacct
    20281 ccttatcgat aagtttttcc caattaaaat catatctcaa gaacgcccgt tattcacatt
    20341 ttgttcataa atgatgtttt ttgtatcata atcgtcaaaa agaggtcgtg accacgtcac
    20401 aacctctttt ttaaacggtg ttccagaagt agcttcttcg gaaataagcc gaaatttcac
    20461 aaaaatttga gaaataattt ttgtcaatct cttcttattt cttgaagctg accacttctg
    20521 tcacaacctc ttccttaaac ggtgttcaaa agcttgcatc tgcggtaata agcccaccaa
    20581 acaaaaaata tgaagagcta tttttgcttg ctgttcttat tacttgatgc agaacagctt
    20641 tttcacaacc tctcatacac ggtgtttaat cagctgacct tcggtattag ctcaaaaaac
    20701 ggcaaaatat gtgaaactat ttttccgttt gtttctctaa tactcaggtc aaaacactga
    20761 tttcacaacc tcttttaata acgaagaatc gctgtcagac tcttttcatc tggcgcatct
    20821 ttttgatcca aaataaacac ttttccgcca ttaatgatca catcatctgc taatgcattc
    20881 aacacttgac gccgatcata ttctgtttca ggatcttcac cgaaaccatc agctaagttt
    20941 gacgtagcga taaataaatg tgacactttt ccttctttcg cagctggaac gatatcaact
    21001 aactgatcga tgaatttctt atctaagagt ttattgtatt cttttgattc ttgagctgcg
    21061 agttcacttg acagcttctt cgccccttct tcgatatctc taaaggatag ctgcgcagga
    21121 gaagcagaaa tcgcaacgtc tgcacaataa tagggatttt tagcaatttt tttgaacatc
    21181 gtctgatttt ctggtagagc aaataaataa atcggccatt gttctggatt ttcgaaagaa
    21241 tccttcaagt acgtatcaac tgcttggtaa tagttgaccc aatcgatctc tacttcttca
    21301 tcttttggat ttacgccatg gaaagttact ccatctcggg ctccgcctcc tccattagaa
    21361 gagaagttca aaccgccacc tgtcagttca gatcccaatg cagtaacgac atcaaccggt
    21421 gccccttctg gtagagatac ttcttttact tgtttgttgc tgacttcata caatttcatg
    21481 gagtcgcggt tcaatcccaa taaataataa gaatagttga actgcccatt tttgataata
    21541 gccagtaaat aaggaagatc acttacatag tattgatcgt ctaccgggat actcaaacga
    21601 tggatatagg tttggtcagc agttataatg accgctacac tcgtagttgc actacgccaa
    21661 aacgaaggat ctcctaacaa attttcaatt ttttcttgga acggggacca gtcatgttcg
    21721 gaatattttt tctcaaaacg tttctttgct tctttcgcaa aatttttgaa tttgatctga
    21781 tctttttcca catcttgatg ggcgacatgc gtattcagca tgatcgtgac gaatggtcct
    21841 ttagcgcctt ctgaagtcaa ttgtgacaat aattctttat ccttttttgc cataaacgta
    21901 cccctcctaa aaaaatcatt cctttgtttc tatctaaagt ctaccacaac actatttttc
    21961 catacaataa aacgtatcta aaaaaataaa acggtttcta cggttttaaa tttagctatt
    22021 tttttaagtt atcttcataa tttcctcaat tatttagccc cagtcttcaa ctattcttca
    22081 tgaaatgctg ataaactaag aaaaagaata aaagaggtgg atcttatgca tttgattatg
    22141 attttcagtt tattaagtat tatcagttta tttgctttca gcgcttcccg cttattagat
    22201 gcggaaacac agcctattcc tgtaaaagta cgtaaaaacg accgctaacc ttccataacg
    22261 tgcgttctta tcctaaagtt ttttcagaaa cattgaaact ctctcccctc tctgataaaa
    22321 ttttaatttg tagcgaaaca aattaattac aaggagatcg gatatgtcca taaaaaaaac
    22381 acgtctagtc ctattattgg ctagtctcat tctttgcctt gcttcttttc taccagctgt
    22441 tgctgtgcaa gctgaagata ctttcaaagt aaatgcaaaa gcagcctttg ctgtagatgc
    22501 gcaaagcggt aagattcttt atgatcaaga tggagaaaaa accatgggga tcgcttcaat
    22561 cacaaaaatc atcggtcttt acatcgtcct tgatcaagta aaagaaggga aactatcatg
    22621 ggatgataaa gtttcaattt cagattatgc agaaaatttg agtgtcaccc cagatttatc
    22681 aaatgttcct ttgcataaag aaaacaccta caccgttaaa gaattattcg actctgcaat
    22741 catccagtca gccaacgctt caatggttgc cttggcagaa aaaatctctg gcagcgaagc
    22801 aaaattcact gaacgaatga aagaacaatt gaaagattgg ggtatcaaag atgcaacgat
    22861 cgttaatgca tcaggactga ataactctta tcttggcgaa aaccgaccag aaggtactgg
    22921 agaaaacgac gaaaatcaaa tgtctgctca agatgtggct atcgttgccc gtcatttgat
    22981 cttggatttt ccagaaatac tggatgtatc tagcactacg acacaaatgt ttggcgaaaa
    23041 cacgcaatca ccagtagaaa tggtcaactg gaactggatg ctcccaggat tcgtgaatta
    23101 taaagaaggc gtggacggat taaaaactgg tacgactgaa cttgcaggag cctgtttcgt
    23161 cggtacgatc actaaaaacg atcaacgaat catcactgtc gtattgaatg cagacggcca
    23221 tgcggaaaac ccaagtgccc gtttcaatga aacagctcgc ttaatggatt attgctacga
    23281 caattggtca gaaaaagagc ttggaaaagc caatgcaagt atccctagtc taaaaaccat
    23341 tgatgtaaaa gacggaaaag aatcaacagt gcccgttgtg cttaaaagtc ctgtaaaagt
    23401 atgggtacgg aacgatatgg atactggaaa attaacaatc acaccaactc ttgacaaaaa
    23461 acaagtcact gacaatgaga tccaagcacc tatggataaa ggaacaaaaa tcggtaccgc
    23521 aacgatcacc ttggcagaag ataaattagg ttatcttgaa gacaacaacg cgccatccac
    23581 agaaatcatc acggataaaa ccgtagaaaa agcaaatatt ttcgttattg gctggcgacg
    23641 cgtcgcagaa tttttcggta acttgtttta attgaacaaa aagaaaaaag catctttcca
    23701 tgtggaagat gtttttttgc tttttctagt ttaaataaca gcttttttca tctattttcg
    23761 ttatactgta taagaaaaag gagttgaatt tatgaatcta accagagatc tgattttttt
    23821 ggttctctat cttattgggg tattctccat cgtttattgg cgaaaacaga aaaaggatcc
    23881 ttccttgttc ttttacagca gtacatggac gtttgcggta atcttgactt attttgtcgt
    23941 gttggaaatt ttttattcga ccttttattt tttgattccc ttagtgtttt tcagtatctt
    24001 tgccttttcc tatttttcag aaaagcgaag gctgttgaat ggtcttttat tcaatatttt
    24061 cctcattagt tttggtatct acttgtttgt cttgctatac gaaacacaaa atatttttct
    24121 tggcggactg attgccttga tcacgatccc gttactgctt gtctttctat tcggcattta
    24181 tggattgatc gtttttcttt tttggaacgg tgtcacagtt ttacgtagag agtcgcattc
    24241 attagctaat cttttaacgt tgatactagc catttttctt acattgtttc ttgtttttga
    24301 ctttttcttg ttaaaatatt taccacaatg gataaatgct ttgtttttct gcatcccatt
    24361 gatcttgatc tatctattta tcgtattcta caactttttg actgtctcat tcttgtatca
    24421 gttcaaccgc cctcgataca accaagactt catcgttgtg ttaggcgccg ggttgatcaa
    24481 tggagaaaca gtttctcctc ttcttgccaa gcgaatcaat aaggcgattg ctttttattg
    24541 ggcacaaagc cgtgcgacat taaatccgcc tatcctatta atgtcgggtg gacagggagc
    24601 agacgaaaaa gtaccagaag caatggcgat gaaacaatat gccatggaac aaggaattcc
    24661 tgaaagagat attcttgtcg aaaccaattc gacaaccact ttggagaata tgcgctattc
    24721 aaaggaaatc atggatcagc aaatgaaagg tccctatcgc gcgatcttca gttccaacaa
    24781 ttaccacatt ttcagagctg gtctctatgc acgacaagcg aaactgaagg caaatggcat
    24841 tggggcaaaa acagctttct attacttgcc taacgcgttt ttaagagaat acatcgccat
    24901 cttgatgatg aacaaaaaaa gacatatgat catttgcgga ttgcttttcg caggttccgc
    24961 attcttatca ctgatcactt tacttttcta aaaaaacaag gtgtgacaaa acatatgtca
    25021 caccttgttt ttttctttta ttctcttgac gattggcaag aatagtattc cttttttgac
    25081 ggctacttgc tgtgcagaat aaataccgct gtttcctgaa cacataaagc tgatcaagca
    25141 gatcataaag aagtaagcag cagcttgtga accaaataat tcgattccca tcacaaaaca
    25201 ggcaatcggt gtatttgtcg caccagaaaa taccccgata aaacctaatc cagcaagaaa
    25261 aggaacagaa acatggagca aaggcgctag tactgcgcca agcgttgcac caatctcaaa
    25321 tagtggtgtc acttctcccc cttggtaccc cgcacctaaa gacaagaccg tgaagaataa
    25381 tttcccaata aaatcataag catgtgcctg tccattaaat gattcctgca gtaacggaag
    25441 actcaaccca aggtaacgtt gtgtttgcaa aatcaacgct gcggctacaa ctactgctcc
    25501 acctatcgta tttcgccaaa caggatgagg aatccattgc gcataccgcg cttttaaaaa
    25561 gacgatcgaa cggctgaata cccaaccaat caaaccaaaa gcaatcccag caacaaaaac
    25621 tttgaagaac agcaacatac tccattcagg aatcacaccc atttggtaat gtagatgaga
    25681 aacaccatag ctttctgtca tgaaatttgc aaaaagcgca gcaaagaagc taggaaatat
    25741 tgcttctgtt cggactttac cgattgccaa cacttctaat ccaaataatg ttccagctaa
    25801 aggtgtgcca aatacagaac taaaacccgc actgattcca ctgataacca aaatctcccg
    25861 ttctgcttta tccaatcgga ataaatgcgc tatattatca gctaatgctc cccccatttg
    25921 aactgctgtt ccttcacgac caacagatcc cccaaataaa tgggtagtga tggtcccaaa
    25981 caaggtcaat ggaatgagcc gcaaagggat cttctcttct cctccattcc cttgatcgat
    26041 cactaagtta ttcccacgac tagaaagacc gccatgatac gcataaagat aagcaaaaag
    26101 cgcgccgctg actggcaata gataaagtag ccaaggatgt gctagtcgga tatctgtcac
    26161 gaacgtcagg ctatttaaga aaaaagcaga caagctcccc atgaatactc cgagaatcgc
    26221 tgtgaccacc agccacttca acatgtacat caaaatacgc actggactcg gtaattgttt
    26281 ttccataaaa aattcctcct caaataaaaa aacgcctact aaagaaaggg gctggcccca
    26341 gactttagta ggcgtcatta gctatcttac gttagcattt aaaggcgaac accatcacct
    26401 attcacttcc attaaaagat agcatatttt tctgtaaaaa acaataaaat tatcgttatt
    26461 tctttacacg ttcagcaaat tcatagaaag gagccaattt cgttaactgt tgattacatt
    26521 gatcactatc atgacaaata taattcccct ttttcgtata cgtgccatca gaaccggctt
    26581 tcgttgtaga aagaaagagc gagacattcg atgttttctg acagatcgca cagattccct
    26641 tattaatcgt tggtgataaa gtaccgctga tcccttttaa ttttccatct tcgtaataaa
    26701 ccatgaattt tttttgcgtc cctggatcat tccaaccgat gtacgtatgt gcttgcaagt
    26761 cgatttcatt ccaagcgggt tgtttgagtt ttttcacttt tcggaataat ttctcgattt
    26821 gtggtttgct cggctgcata aacggctgga cgatttgctt cagctcctcc aatgctcgtt
    26881 ctgcttgcgt ttttgtcagt tttacatcta aaactgtcgt taaaaacgta tcgatttctg
    26941 atggttcgta acctaataca tcgcgaatct tttcagctgc tagagcctga accgtttgta
    27001 ccgtttttga gtcattgaca gatgagtacg catttaataa ctgctctact tctcttttta
    27061 taaaaaaata ttgatatggt ttcattgttt gttccatgat tttaaagtcc tttcttctaa
    27121 ccaaagtgca tactttgtag aaaaaagtga tcttctgcaa agtatgtgtt acctgaagat
    27181 cccggactct tttaaataag atacgttttg catcttatca tcaccccctt taatgttcat
    27241 tcttctatgt acatgattca ttcgataaat aaaagtaaac cgtatcttga gcagatagtc
    27301 aactgcaaac agaaaaagga ctgtgacaaa agtcgtgtca aagtcccttt ctacaaacaa
    27361 acggtgttcc agaagtagct tcttcaaaaa ataagccgga atttcacaaa aatttgagaa
    27421 gcaattttcg taaattcctt cttatttctt gaagctgacc cacttctgtc acaacctcaa
    27481 tatggtctat tattggtttt acctgttaaa tcgaggattc ttttccgaag taacgttgcc
    27541 atctcttacg catacttgct gacataggct gagcggcttc tttgactgcg cagtatttgt
    27601 ctacgaatgt tacgatatat ccttctttgt acttaggcgg tgcaatcgtt gcgccccaca
    27661 tgtgcttcaa aatgatatct cgctcaagat ccgacaaatc ggtgatcttt tctgcattct
    27721 ttacagcgat tcttggatgg atatacgcat gtgtgccttc atcaaatttc gtcgtacgcc
    27781 aatcatagta gaacagatca tgcaaaagtc cagcacgcgc tgttgcttta gcattgccac
    27841 cccatttttt tgcgagcaga taactatagt aagaaacact gatggaatgc tccaaacgag
    27901 tggaatgaac atgctgtgtg taattcgcta attttttcac tgcttctgtt tctaaaagat
    27961 cttctacata agacatatat tcttcgtctt cacgccattt ttctgtcata attatcgatc
    28021 tgccaccttt ttgaatttca ttttcttctg aaattgatct aagtatacca ccagtgttcg
    28081 gattattcta gtcgccttgg ataaaatagc caaagcttaa tagttcctta atcataaaga
    28141 aaaatgataa agaacaatcc ctgccgcaac cccaacattc aacgattccg catttccttt
    28201 catcgggata tatacgttct gatcagtcaa agacaagatt tcctgactta ccccctgacc
    28261 ttcgttcccc atgattattg cgaagttatc tgatttttct actttgtcta aggcgtgtgc
    28321 ttcttcattt aattctgtgc catacactgt aaaccctttg tctttcatta aaggaatcac
    28381 ttctgtcaaa tctttttgca acacaggcaa atgataattg cttccctgca tgctgcgcag
    28441 cacctttgta ctataaatat ctgccgttcc tttgcctaat aaaacaccag ccatatcaaa
    28501 tgcatctgcc gtacggatca tcgtccctac atttccagga tcttgtacat tatctaataa
    28561 cagccatcct cctgaaaaat ctggcgtgcc ttcagccgtt aacgccatca ctgctaagat
    28621 tccttgtggt gtaggtagat ccgatacagc atccatgacc tcatccgaaa ctagaaaagt
    28681 agaaatctct ttgtttgcgg ccagccagtc tccccattct ttcatgcctc gctgtgtcac
    28741 aaaaagttct tttatttctg catcagacga cgcagcttct tcaatcagat ggaacccttc
    28801 caaaagatat tcttcctttt cttcccgata tttcttttta tgtagttttt ttaattcttt
    28861 gattcttgga ttttttgctg attggatctc tttcacattc ctcacctccc catgattata
    28921 tcatggaata ggtgcttgag cttgtttcat cctaaaaaaa tcggtatcat taatttataa
    28981 aataggaaag aaaggtgacg aacatgcgca aagttaaaat gaacgtccaa ggacgcgtcc
    29041 aaggcgtagg atttcgctac atgaccaaga tggtcgctga tcaactaggc gtgactggaa
    29101 cggtaaaaaa cgaagatgac ggctcagtca cgatcgaagc aatcggcaat gacgacatca
    29161 tccagaaatt tattgaagaa gtcaagaaat ctccgagccc aagtggacga gtgcagtatg
    29221 tggatgtcca agaagacccg atgattgagg aacgaaagaa atttgatgtg gtgggataag
    29281 gttgtgaaaa agctggtctg catcaagcat taaggacagg ttgtgaaaaa tagctctcca
    29341 tatttttcaa caggctggac ttaatgccgt agatgcaagc ttttgaacac cgtcaataag
    29401 gttgtgagaa agtcgcttag ttttgagtag taaggagaat tttgtgaaaa tggctttcca
    29461 catttttgca taaaatttga cttaataccg agaaactgac ttttgaacac cgtcgataag
    29521 gttgtttttg agacgctttg cctcaagtat taaagatagg tagtaaaaaa gctgatctat
    29581 aacttgcaat aaatttgctt aacccatatt ttccagacag aacaaaaaag tttttagttt
    29641 tttaaataag aaagaaacac ttggaatcac tcttttcttt ccaagtattt ctttcttgat
    29701 tttttgtctt tttttcaaaa tttttcgcta cgtaaaagaa cgaatattta tatgaaattt
    29761 ctatgaagtt gattgaattc catgcgcttt tttagtatag ttaagtttgt gtaaaaatta
    29821 tagaagagga agtattctat gaataaatgg aaaaactggt tattgggatc cggacttgtc
    29881 agtatcctgc tctttttatc tggctgtgtg cggatggatt caaacggaaa ccctgacact
    29941 tcgggaatcg tttatcgagt actcgtccat cctatgggcc aagcgattac atatctagtt
    30001 gagaatttca attggtctta tggctgggca gttattgcaa tgactgtgat cgtccgtatc
    30061 atcatcttgc cactaggtat tagtcaatcg aaaaaaacaa tgatccaatc tgaaaaaatg
    30121 caagcgttaa aaccacaagt tgaagcagcc caacaaaaat tgaaagctgc aacaacacgt
    30181 gaagaacaaa tggcagcaca agcagaaatg cagcaagtat accgcgaaaa cggattgagt
    30241 atgaccggcg gaatcggctg tctgcctcta ttgatccaaa tgccgatctt ctctgccttg
    30301 tactttacgg cacgttatac agaaggtatt cgggaatcat ctttctacgg catcgattta
    30361 ggctcaccaa gtatggtact tgttgtcatt gcaggggtcg cctatctgct tcaaggatac
    30421 atctcaacga tcggtattcc tgaagaacag aaaaagacga tgcgtacgat gctaatcgtc
    30481 tctcctgcta tgatcgtctt catgtcgatc agtgcgccag ccggtgttac actttactgg
    30541 gtagtcggtg gtgtgttcag ctgtctgcaa acattcatca caaacgttat gatgaaacca
    30601 cgtttgaaag cacaagtggc agaagagttg aaacaaaacc cgccaaaaca agtcgtcact
    30661 ccaagaaaag acgtgacaga atcagcaaag ccagctaaca acaaacaagc aacaaaacaa
    30721 atcaaacaac caaaaaacag tacaaacaac aaaggccgca acgcaggaaa gcagcagaag
    30781 cggaaataaa aacataggac aaaaaagatg agagctaagc cctcatcttt tttgttactc
    30841 ttcctcttct gctattccat taattaattc gttgacagag acaatgcttt cacatcctgc
    30901 acgaacaaac tcgggctctg aaccaatcat ttgtgagttg ataaattcaa tgaccatcgg
    30961 aagattcatc ccagcataaa gagtaatctg ttgtccttcc attattagtt tagaaatgat
    31021 atttgcaggt gtaccaccta aaagatcgca tagtaccaca aaatcattta acgaatctgt
    31081 gacagtgaga aacttttgtt tgtatgtttc agtgccatct tctggtaata aaggtaacgt
    31141 gtagatatcc tcttgaggcc ccatgatcat ttctgtactt tttttcaatt cctcacaaaa
    31201 ttttccgtga ctaatcaata ccaattgtct actcattttt cgctctccct tatttcgaaa
    31261 tcacacccaa tgcagataaa gcaacacaca caattaatac gataaaaatc gctcgagtag
    31321 gagtcatgtt tttctttcct aataaccaat aaacaccacc gacgatccca gcaggtaaaa
    31381 ttttaggtaa gatcatatcg atatagtttt gcatattcaa tgtcacatcg ccaatcgttg
    31441 gtgcccatga aaatttaaca ttgatcattg tcgcaactaa tgcccctacc atgaataccc
    31501 ctaataaagt ggctgcgtcc gttaatgcag ttaagcgaga ttgcatagta gtaactaagg
    31561 aaattccttc tttgtatgca aattcaagtt gcttccaacg aaaaaccatg acaacgatct
    31621 gagcaaaaat ccatataaac acacctatcg gatttccatc agttgccata ttcgccgcca
    31681 aagccccaaa aatcgttgga atcaaagcag caaatacgga atctccaatc gctgcaaagg
    31741 aacccatcaa tccagctttc agccccgata cggtttcctt tgaagcaatt ccctcttttt
    31801 cttccattgc aagatcaatc ccagtaatga ttgtattaaa aaaattagaa gtattaaaaa
    31861 attgcgtatg tgttttcatc atctctttta attctggtgt attgtctcca tatatttttc
    31921 ttagttgtgg caagatagta tataaatagc cagaaccctg cattctctca tagttccaac
    31981 ctaattgaaa agtgaacaaa cttcttcgat tgatttgctt aaaatcttct tttgttaatt
    32041 tgtaattaga tttcgtcatc ttcgatttcc ccctcaacag aatgtgatgg ctcactagct
    32101 aatggttgat ggtctttgtt ttgatcattc ttataactga tcattgctag tgctagacca
    32161 atcaatgcta cagcaagcat cggcagcgaa ttgaaagttg ccggaagatc tttaacaacg
    32221 cttgccacac ttgttcctaa taattgaaca ttagagaata acgttgctaa taatgccgtg
    32281 atcgtaaatc ctaaaataag ataagataga tgttttttta ctggtaaata gcgcagaaga
    32341 atggcaaacc caacagctgg taaaacagct cctgctactg aaagtccatc gcctagccat
    32401 tttagattcc cgtttaaaac agaaacaaca ttttcaacta atccaccacc aaatgctaaa
    32461 gctaaaaata caggaatcat acgagagagc gaccaaggta aagctcccat taagaaattg
    32521 cgttcgattg cttgataatt catgtcttct acgtgacggt caatacgatg ggcaaagtat
    32581 gtgttagcga atctagctaa aatatccaat tggatcatta agcttgctac aggcactgca
    32641 atagcagcaa tcgcttgttc tggattcatt ccaagagaaa tcgagaaggc agttgctaaa
    32701 atcgtcccag agttggcatc tatttttgat gcgcctccaa acgtccccac tcctaaaact
    32761 gtcaactgca tactgccacc aataatcaaa cctgcgttta aatcacccat tactaaacct
    32821 gcatataacc ctgcaaacac tggcgcactc attgaagaat agatctgtaa ttcatctaaa
    32881 atttgataac ctgcatataa tgttaataat aagatctgcc accattgaat atccatggat
    32941 cattcctcct atttgattaa aagattcata aagtcttctg ctttatcgtt tggtaccatt
    33001 tgagcaatta aatgtatacc aagctgatct aattttttaa atacttcgat atctgcatct
    33061 accacattga ttgattttgt aatggaccgt gtttcattcg tttgtgacat attccccaca
    33121 tttacttctt tgataggaac tcctttttct actaaagata agattcgatc tggctttttt
    33181 gctacgatca atactcgttg agagtcatat ttgccagcta aaatatttgt tgctgctttt
    33241 tcgattggca aaatgcttaa ttttacccct gctggagtcg ctaacttcaa tccacttttt
    33301 tcaattgtgt ttgtggctac ctcatcatcc acgaccatga ttcgactaat attcagtttc
    33361 gttgtccaaa gatttgctac ttatccatgt atcaaacgtc catcgattct tacaccaata
    33421 attgccatca tgcattctcc ttatctattt tttctattta ttgttcaatt aaaactgtga
    33481 catcatcaaa tatcccttct gtttcaaaga taacgttttc attttttctt tcttatattt
    33541 catttttaag ctaagaacaa attccttccc aactaaagaa aacgctttct tttatattta
    33601 agttcatttg attttcttaa cttgaatgtg tttcatcaac atcgtaactt tcatagggtc
    33661 gatccagcca gttttctctt gttgcgcgtt tgccatacca caagccatag aaaatgcgag
    33721 aatctcttcg attgattgcc tttttgataa cgcatgggcc gatcctgcaa gggtcgcgtc
    33781 acctgaacca acaggattaa caactgatat tttaggaata atgacttcgt aaaaacactg
    33841 agcaactttt gccacagcac ctctctctcc taaagaaaca acaacccatg gcactccttc
    33901 aaatattgga tgagctaata aggactgaat tttttctaat tgaatcgaag aacagatacg
    33961 ttggccaatc agttctccta attcttccag attgggcttg ataagtagtg gcttctcctt
    34021 accttccaat acttcaagca aaaatttacc agaagtatct agtaatatgt ctttcccttt
    34081 tttatcagct aaagcaacca attgcttata gtaatcaaga gggcatcctt ggggtaaact
    34141 acctgagatc gtcataatat ctgatatttc gaggagctgc tcgaaatgat cggtaaatgt
    34201 ctgttgttct ttctttgtta tgaaggggcc tcgttccaaa agctctgttt gtctcgaact
    34261 atgcaggata gcaatagaat cccttgtctc tcctttaatt ggaacaaact gatgcatgat
    34321 ccctaactga tctagctggt tctttagata ttcaccgtgc tggccaccta ttaaaccagt
    34381 agctatcacc tcttctccta ataaatttag aaccctcgcc acattcactc cttttcctcc
    34441 cgctgtttta ttgactgttt caactcgatt gactttgtcg aggtttaatt cttcaattgt
    34501 atacgcgata tcgatggaag gattcaaggt aactgtcgta atcatttcat cttcaccttt
    34561 ttgctttttg ttttattgaa ccaaggggta gcggtttcat ttattacttt atttaaagtc
    34621 tcgatgtttt ctctcccatt tgttcttaac caatgaatag ctccgtcttt tccattttcg
    34681 acgtatgctt tgaccccatc tttccatgtc gcacgtccac acaatacacc attgaaggtg
    34741 gaacccgatt catgagcaaa aatcagtgtt tgttgaaata attctgttga aacaccccca
    34801 ctcaaaaaaa tgaatggtaa tggagtcgct tcactttgct ccttaaagaa ggcagcagcc
    34861 tcttctttgc tgtgaataaa ttcacctgtg gaatagccat tcacataatt catattgact
    34921 ggtacttcta ctttcaacac atcaacttta tattttggat cagaaaattc tttcatcatc
    34981 tcaataactt tgtggggctt gactttcgca tactctggag aagaactatc gcttatttgt
    35041 gcgtcataag aaactaactc caaatagaag ggacgatttt ctccttcgca ctcactacct
    35101 aaacgttcga tgaacacatg cttcaaatga ttgatttcgg gtgcttcatc aacatcgtag
    35161 taaagtaaga attttactgc atccgcttgc tgttctttca atctgagaga agaccaatcc
    35221 gctaataaat caggtagacg accaggcgta gttgcgtcat agccggtttt ctcataagct
    35281 aacaataacc ccgtctcttt tgctctgact tttgctgctg gcaatccata ttccggatcc
    35341 aataaaatag cagaagcata gggtgtcagc tcagctgata ctagttcttt gaattcactg
    35401 atttggtctt cacttggctc ttttcccaac gatttgatca ttttttttag agcaccacgc
    35461 tgatcgatcg ctaatgcact aataatccca tcttttgttg atagtctctc cattgcccta
    35521 tttttttctt cattcatctg tcatttctcc ttcggtttca tacttatgaa taatgacgcc
    35581 cttgactact cgattgaccg tgcctgttgg agatggtgta tctggtttat tagctacttt
    35641 gattgaagta tagagtgcaa tgatttgtgc agtcataatc atcgctaatg caagataggc
    35701 atcgggcaat ttactcaccg agtcttccaa tagcacagtc atacctgaga aatcaatagt
    35761 acccggttgc gcaatcgcaa tgacattggc agtgacccga tcttctttta tttcctctaa
    35821 aatatctaag tcataatttc gcgtatatgg ttgattgctc acaaaaccta caacgagtgt
    35881 ctcgctattt aaaaaagact ttggtccatg acgaaacccc atcgaagaat caaaaattgt
    35941 agcaacttta cctgctgtta attctaaaat ttttaattgt gcttctcttg tcgcacctgc
    36001 caaacttcct gaacccagat aagcgatccg ttcaaaaaaa tcaggtaata acttttgaat
    36061 ttcttgatct cttgaaagaa gatcttgacc gattttaact aattgttcaa gatatctttc
    36121 ttttttctcc attgctgttt gatcaaagat ccataaagca ctcaataaca tacacgtaaa
    36181 acttcctgtc atagcaaaac ctgcatcgtt tgctctctct ggcatcaata acagataatt
    36241 ctgtttatca tcctgtgcgt tttttgccaa catcccctct ttagcacaag taatcgtcaa
    36301 atgaaacaat gtttcaactt gttcatttgc aatttgcaca gccgctacac tttctggact
    36361 gttgccactg cgagcaaatg aaactaataa agtcggttca tttggaaaca aaaattcttt
    36421 tggtgaagct acaatatctg tcgtgccaaa actgtggaag ataaaaaact gattgtctcc
    36481 atgttcattt agatagggta agagcgtatc cccaatatat tgagacgttc ctgcacccgt
    36541 aaaaataaca cgtattcttc ttccgtttgc ttcttttttt atttgatcaa aaaatagagc
    36601 taaattttct tggctttgca tcaatctatc gattgtttct ttccagagat ctggttgttg
    36661 ttttatttct tgtgtcgtga ttgctgcacc tatttgtttt aatttgttct tcgatagctc
    36721 aaacatgttg ttctccctct caatcatttt cggatatgcc gaattttata atgaaactgg
    36781 tccgctcttg ctacactatc tgtatattcg ataatctcat ttttcacgtt ataggttatc
    36841 ctcgtcagat gtaagacggg agcgccatca gcgattcgta gcacaacagc atcttttttt
    36901 tgcacgatac ttgcataaaa ctcttcatca gctaattgaa cttgttgttc ataatcctgt
    36961 gaaaacacat catacaacgg tttactttca agtaacggca aatcaagtcc cataaatagt
    37021 ttcgccggta gataagaacg ctcaaccatc aatggctctt catctgccaa acgcaatctt
    37081 ttaagtttaa atacagtttc acctaaatgg atgttcaaat tcttagcaat tctcttatta
    37141 gcttccattt gtctaaattc taaaatgacc gtcttaggga cgcgccctat ttcgcgcatt
    37201 tcttctgtaa agctatatgc tccagctaag ttcgatgact tatcagacaa atcagagaca
    37261 taggtacctt ttccatgtct tcggtaaata taaccttgat tttccaattc ctgtaaagcc
    37321 agacgtacgg tggtacgact caccccatag tgttgacaaa gttctctttc agataacagc
    37381 ttatcatgcg gagtcatctg tgtttcgata cgatccttca ataaatcaac tagttgataa
    37441 tacaatgatt ttcctttatt tgagctctcc ataaaaatca cctcttcttt actggttata
    37501 accacaacac aagaatagtg aattattaat catttgtcaa aggtttttta gaccaaaaaa
    37561 gctattataa cagctcttta aagctttata tcttgaatag acaaagatac ctcaaaaata
    37621 ccagttacca ataaaagaac agaaaaaaag acgaaccaca taagcgatcc gtcaaaatgg
    37681 tctaacttat cgagcagcgt gatccacatt aatccctatg atattcctac aactatcgtt
    37741 ttattacttc caatatcatt tacaacaact aaaaatagct tattaatgac aaatgttatt
    37801 attagtttta gataactttt gcagttttat actttttttc tataaaattt gacaaacatt
    37861 tttttaaata actaattatt ttttgaatct gtcactcaga caatcctttc tcttacttgt
    37921 taacataaat agaagttgct gtttcttcta atagtgtact taattcttta atattttgtt
    37981 ttccttcttc taacatccaa ctactcgctt tttcttcgcc ttcggtaaca aaaggtgcta
    38041 ctcccttcgc ccatgttgct cgcccacata agacaccatt gaatgtcgaa cctgattgtt
    38101 ttgcaaaacg caatgtatct tgaaatagtg cagcgctgac tcccgcactt aaaaaaataa
    38161 acggttgttc agtcactttc gattgttcat agaaatacgc ggatgcctct gcttgactat
    38221 aacaagtatc ttgcccatat ccttccacaa atctcatatt cactggtact tctactttca
    38281 atacatccac ttgataacgt tcttttgaaa attctcgcat ggcttcaatc actttatgcg
    38341 gttttacttt tgcatagtca agagaagacg gatcgccaat agttgcatcg taagaaagga
    38401 gctctaaaaa gaaaggtatg ccttctgctt cgcattctga accaatccgt tctataacta
    38461 tttgtttttg cacattaatc tctactggtt catcaacgtc atagtacaat aaaaatttac
    38521 aagcatccgc acccacttct tttaaccttt tcactgacca actattcagt aaatctggta
    38581 gtcggcctgg cattttcgca tcatagccgg ttttttcata agctagcaac aaaccacatt
    38641 ctttctctcg aagcgctgct gcaggcagac catattctgg atcgagtaaa atagcggaag
    38701 catacggagt caggtactga gaaaccatct gtttaaattg gatgatatct tctgatgtag
    38761 cttctttata ttggttgatc attttcttca aagcaccacg ttggtcgata gctagcgcgc
    38821 taataattcc agcttcatcc gtcaatcgct tcaaacgttc ctgtttttct atactcattt
    38881 tcttcatata tcttcaccta tttctttagt taatattgta gctatttcta tttttgattt
    38941 tgcagctctc aactgttctg taacctcttt tcgcatcaat gatcgtgcaa cgagagacaa
    39001 taatttcaaa tgagtcgttc ctgcttctga atctgggata aataacgcaa aaataaaatc
    39061 aactgactgt ctatctaaac tgttccattc aattcctttt ttcagtgtga cgataatcaa
    39121 actaggttca ttgattgttt gagacttcgc atgagggata gcaaaacctg acattattcc
    39181 tgtagtacct tctttttctc tttccagaag tttttgatat acttcttttt cgtcatgagc
    39241 gattcctaaa cagaatgttt gctttgctaa aaacttaaat gcttcttctt gattatctaa
    39301 tggctgttgt aaaaaaatgt tctcttcatg aatgattgtc atgataaacc tcctgctctt
    39361 ccttcttcga taactgtacg atttgttgct ttattatccc tcttcttgtc tttatcagtt
    39421 actcttttct tttggatcaa acctagtatc actccaccaa cgatcgaacc aataagaatc
    39481 gctgtaaccc attggatttt tcccgtcact acaggtaaca ctaaaaaacc gccatgtggg
    39541 gctggtactt ggacaccaaa cagataggtc aagacagcag caattgatga gcctaacatc
    39601 atcgttggta atactcggat cgggtctttc gcagcaaacg gaatagctcc ttccgtaata
    39661 tgagttgatc ctaaaataaa attaaccaaa cctgcattac gatcattagt atcaaaatat
    39721 ttaccaaaca ataaagtagc aaaaccagta atcaacggtg gtgcaatgca agctgctgac
    39781 gcaccagcca taaaagtcgt gtttccttgt gtcaaaagag ctgttcctgt tacatatgcc
    39841 gccttattaa ccggtcctcc catatcaaac gcacacatac agccaacaat cacgccaaga
    39901 acaagtggat tcgaatattc aaatccagct aaaaagctca tcattccttc atttatagcc
    39961 ttcattggac ctgccagcaa agacatcacg atgccaataa atgctacacc aataactgga
    40021 tataagacga ttgccttcaa gccatctagt tgtttaggta aaattatcag tagcttttgc
    40081 aaaaataaga taaaataacc tgctaagaac ccagctaaaa tacctcctaa aaatccagta
    40141 ccgccattca tggctacgat tccaccaaca aatccaacga ctaaccctgg acgtttcgcg
    40201 atcccttctg caatataagc tgctaaaact ggaaccatca ttcccattgc tgcatcgtca
    40261 actgctttta ccattgccgc tgtagcattg tattgtgcat gatctggatc agaagaatag
    40321 attccccaaa cggcaaatga aatagcaatc aatactccgc cagctaccac gaaaggcaac
    40381 atatgagaga caccgttcat caaattttta tagatgctac gaccaaaatt agcaccactt
    40441 atcgcttctg gttctaaagt atcagcagct tcattatctg ctaagacagt accttttcct
    40501 gccaatgctt cgtcaatcag ccgttgtgca tccttgattc ctgtactgac agaaacatca
    40561 atgactcgtt ttcccacaaa tctttctgaa tggacatctt tgtctgcggc aataatgaca
    40621 gcatctgcct gtttgatttc ttcagccgtt aattcattct cgatcccaat ttgtccatgg
    40681 gtctccactt tgatcgtgat gccttttttc ctagctgctt gctctaatgc ctcttgcgcc
    40741 atgtaggtgt gcgcaattcc tgtcggacaa ccggttgctg caattagttg atattttccc
    40801 atctttcgaa cctctcttcc ttgattttga tttgtttact taattcctcc acatccaaaa
    40861 aatcagtcag tcctttacga aaagcagtag agctgcctgc tgctatgctt ttacgtaacg
    40921 tttcatcaag cgatcgtcga ttcatgtatc ctgctaaaaa agtgcctaac atggcatcac
    40981 ctgcacatgc tgtattgaca acttttcctt ttggcgagtt tcctcgaatc accctgtctt
    41041 tcgtaaaaag aatcgctcct ttctcaccga gggataacaa aacattttct gcgcctgact
    41101 ctactagtcg ttgtccataa acaaagtaat cttcatctgt aaccattttt cgtccgaacc
    41161 aagaagaaag ttcttcctca tttggtttca gcaaaaacgg tcgatagggt aaacaatcca
    41221 tgacttcttg atcactacta tcaataatca aacaaatccg actgatttct attaaaacct
    41281 ttggagacag ccctcttggt aaactcccag aaacacaaag ataatcccct gcttgtaatg
    41341 ctcttatttg atttaaaaaa ttatgaacag ctgtctgcgg tatttcaggt ccttgattca
    41401 ctaatttgta ttcttctccc gtttgattga cttgtgtaaa tacattgata cgcgtcatac
    41461 caggcacttc aataaactct gtttggattt gtttctgctg taaatagtct tctatatact
    41521 ttcctgtgaa cccagcagaa aaacctaatg ccgtacttgg gaaatctagc atctttaata
    41581 ctagtgacac attcacccct tttccgtttg cctgaatgtc atcctctttt gtgcggttta
    41641 ccataaaagg atgcatctca tctgtttcaa taaatagatc aattgccaaa ttcatcgtgc
    41701 atgtgtagat agacataacc aacgacctcc ttgattctat tatgaaatac gcgaaataga
    41761 aaatgttttc ttaatcgtcc caacacaaag aaaaccttta catttataaa ctcgtcgtgc
    41821 tttttttaac taacttttgg tgaaagaagg aaagaatatg aatcacaaat taagtgaaac
    41881 agagcagtac ctctggaact ttatcgaaca cctcatccta gagatcccta actattccat
    41941 cgtgaaacta agtgaacaag caaatgtctc aacagccacc attgtgcgga caatgaaaaa
    42001 gaaaggctat gaagggttta cttcgtttaa gcatcatcta aaagaaggag aaaacaagaa
    42061 catcaatttt tcatttttag ataaagtaga caaaggaatc cgccgagcca ttctaaaaaa
    42121 tgaacaagaa gtggtacgta caatcaatat gttggaaatc gggaacattg aagatgcaat
    42181 acaaagaatc aaatttgctg accgggtttt tgtctttgcc cgaggatttt cagaaatgat
    42241 tggccaagaa atgctggtaa aacttcaatt aacgggaaaa aattgtcaga tgcatactga
    42301 tccagaaatt atcaaaagca tcagtcggaa actaactaag aaagacagcg ttatttttgt
    42361 ttctttgaac ggtgagaaaa caaataaaaa catcaaaaat aagatttatg tctttatttt
    42421 tcaatttttt a
//
LOCUS       DAFLWQ010000016        42379 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.017, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000016 DAFLWQ010000000
VERSION     DAFLWQ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42379
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.017"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(60..1163)
                     /locus_tag="L1V16_000855"
     CDS             complement(60..1163)
                     /locus_tag="L1V16_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBN1275214.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            complement(1385..1855)
                     /locus_tag="L1V16_000856"
     CDS             complement(1385..1855)
                     /locus_tag="L1V16_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HBN1275215.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            2188..3828
                     /locus_tag="L1V16_000857"
     CDS             2188..3828
                     /locus_tag="L1V16_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HBN1275216.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            3982..5304
                     /locus_tag="L1V16_000858"
     CDS             3982..5304
                     /locus_tag="L1V16_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBN1275217.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(5366..5797)
                     /locus_tag="L1V16_000859"
     CDS             complement(5366..5797)
                     /locus_tag="L1V16_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1275218.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(5861..6697)
                     /locus_tag="L1V16_000860"
     CDS             complement(5861..6697)
                     /locus_tag="L1V16_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBN1275219.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            complement(7439..8065)
                     /locus_tag="L1V16_000861"
     CDS             complement(7439..8065)
                     /locus_tag="L1V16_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275220.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            complement(8360..8695)
                     /locus_tag="L1V16_000862"
     CDS             complement(8360..8695)
                     /locus_tag="L1V16_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBN1275221.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            complement(8682..8966)
                     /locus_tag="L1V16_000863"
     CDS             complement(8682..8966)
                     /locus_tag="L1V16_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBN1275222.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            complement(9022..10545)
                     /locus_tag="L1V16_000864"
     CDS             complement(9022..10545)
                     /locus_tag="L1V16_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBN1275223.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            complement(10538..11713)
                     /locus_tag="L1V16_000865"
     CDS             complement(10538..11713)
                     /locus_tag="L1V16_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBN1275224.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            complement(11717..11902)
                     /locus_tag="L1V16_000866"
     CDS             complement(11717..11902)
                     /locus_tag="L1V16_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275225.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            complement(11868..13562)
                     /locus_tag="L1V16_000867"
     CDS             complement(11868..13562)
                     /locus_tag="L1V16_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBN1275226.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            complement(13559..14032)
                     /locus_tag="L1V16_000868"
     CDS             complement(13559..14032)
                     /locus_tag="L1V16_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBN1275227.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            complement(14101..14256)
                     /locus_tag="L1V16_000869"
     CDS             complement(14101..14256)
                     /locus_tag="L1V16_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HBN1275228.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            complement(14390..14770)
                     /locus_tag="L1V16_000870"
     CDS             complement(14390..14770)
                     /locus_tag="L1V16_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBN1275229.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            complement(14774..14989)
                     /locus_tag="L1V16_000871"
     CDS             complement(14774..14989)
                     /locus_tag="L1V16_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275230.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            complement(14992..15399)
                     /locus_tag="L1V16_000872"
     CDS             complement(14992..15399)
                     /locus_tag="L1V16_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HBN1275231.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            complement(15665..17140)
                     /locus_tag="L1V16_000873"
     CDS             complement(15665..17140)
                     /locus_tag="L1V16_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HBN1275232.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            complement(17130..17978)
                     /locus_tag="L1V16_000874"
     CDS             complement(17130..17978)
                     /locus_tag="L1V16_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HBN1275233.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            complement(18015..18377)
                     /locus_tag="L1V16_000875"
     CDS             complement(18015..18377)
                     /locus_tag="L1V16_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275234.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            complement(18378..18536)
                     /locus_tag="L1V16_000876"
     CDS             complement(18378..18536)
                     /locus_tag="L1V16_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275235.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            complement(18677..19301)
                     /locus_tag="L1V16_000877"
                     /pseudo
     CDS             complement(18677..19301)
                     /locus_tag="L1V16_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            complement(19298..19609)
                     /locus_tag="L1V16_000878"
     CDS             complement(19298..19609)
                     /locus_tag="L1V16_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275236.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            complement(19653..19946)
                     /locus_tag="L1V16_000879"
     CDS             complement(19653..19946)
                     /locus_tag="L1V16_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275237.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            20140..20787
                     /locus_tag="L1V16_000880"
     CDS             20140..20787
                     /locus_tag="L1V16_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1275238.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            20848..21993
                     /locus_tag="L1V16_000881"
     CDS             20848..21993
                     /locus_tag="L1V16_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1275239.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(22074..22379)
                     /locus_tag="L1V16_000882"
     CDS             complement(22074..22379)
                     /locus_tag="L1V16_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBN1275240.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(22404..22835)
                     /gene="ruvX"
                     /locus_tag="L1V16_000883"
     CDS             complement(22404..22835)
                     /gene="ruvX"
                     /locus_tag="L1V16_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBN1275241.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(22832..23098)
                     /locus_tag="L1V16_000884"
     CDS             complement(22832..23098)
                     /locus_tag="L1V16_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBN1275242.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(23353..24078)
                     /locus_tag="L1V16_000885"
     CDS             complement(23353..24078)
                     /locus_tag="L1V16_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBN1275243.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(24439..24509)
                     /locus_tag="L1V16_000886"
     tRNA            complement(24439..24509)
                     /locus_tag="L1V16_000886"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(24475..24477),aa:Gly,seq:ccc)
     gene            24626..25378
                     /locus_tag="L1V16_000887"
     CDS             24626..25378
                     /locus_tag="L1V16_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBN1275244.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            25394..25873
                     /locus_tag="L1V16_000888"
     CDS             25394..25873
                     /locus_tag="L1V16_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBN1275245.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(26124..27704)
                     /locus_tag="L1V16_000889"
     CDS             complement(26124..27704)
                     /locus_tag="L1V16_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HBN1275246.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(27697..28440)
                     /locus_tag="L1V16_000890"
     CDS             complement(27697..28440)
                     /locus_tag="L1V16_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1275247.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(28616..29392)
                     /locus_tag="L1V16_000891"
     CDS             complement(28616..29392)
                     /locus_tag="L1V16_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1275248.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(29640..30476)
                     /locus_tag="L1V16_000892"
     CDS             complement(29640..30476)
                     /locus_tag="L1V16_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HBN1275249.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(30487..31416)
                     /locus_tag="L1V16_000893"
     CDS             complement(30487..31416)
                     /locus_tag="L1V16_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBN1275250.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            31608..31961
                     /locus_tag="L1V16_000894"
     CDS             31608..31961
                     /locus_tag="L1V16_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBN1275251.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(32035..32691)
                     /locus_tag="L1V16_000895"
     CDS             complement(32035..32691)
                     /locus_tag="L1V16_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBN1275252.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            32917..34851
                     /locus_tag="L1V16_000896"
     CDS             32917..34851
                     /locus_tag="L1V16_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBN1275253.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(34937..36160)
                     /locus_tag="L1V16_000897"
     CDS             complement(34937..36160)
                     /locus_tag="L1V16_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBN1275254.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(36154..38052)
                     /locus_tag="L1V16_000898"
     CDS             complement(36154..38052)
                     /locus_tag="L1V16_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HBN1275255.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(38046..39164)
                     /locus_tag="L1V16_000899"
     CDS             complement(38046..39164)
                     /locus_tag="L1V16_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBN1275256.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(39247..40080)
                     /locus_tag="L1V16_000900"
     CDS             complement(39247..40080)
                     /locus_tag="L1V16_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1275257.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(40073..40990)
                     /locus_tag="L1V16_000901"
     CDS             complement(40073..40990)
                     /locus_tag="L1V16_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1275258.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(41013..41192)
                     /locus_tag="L1V16_000902"
     CDS             complement(41013..41192)
                     /locus_tag="L1V16_000902"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275259.1"
                     /translation="MNKINENTSNTVLPATYSDATSYLTTAAYNYWQTGDFENSYLKE
                     AENFAHKYGVKLTGD"
     gene            complement(41217..42341)
                     /locus_tag="L1V16_000903"
     CDS             complement(41217..42341)
                     /locus_tag="L1V16_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBN1275260.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
BASE COUNT        12698 a         8586 c         7056 g        14039 t
ORIGIN      
        1 tataaaaata ggagtacggc atcatctgcc gcactcctat ttttttcgtc atttgtttct
       61 taaataaaac gattctcacg caattttatt tttttgatat cttctactgt ttgtgttcca
      121 gctaattgca tgaccatttc caattctgtt ttaaagaaat caaacacttg atggactcct
      181 gtacttcctc ctaaagacaa tccataaata acgggtctgc caatagcaac aagatctgca
      241 cctgatgcga ttgctttgaa aacatgctgt ccgcgtcgta caccgctgtc aaacacgatt
      301 ggtacacgtt tatctactgc ttctgccaca tattgcaacg aatcaaacgc tgctggacca
      361 ccatctagtt gacggccacc atgattagat acccagattc cgccagcacc agattctaat
      421 gaacgataga catcttcttc tgactggaca cctttcacat agactggcaa atcagaatga
      481 gcagcaataa attctacatc ttttggacta agcttctgtt tggaagattt gtacacagca
      541 tccatcgttt ggcctactcc tgattgataa gcctgaacga tcggcattgg cagtgggaag
      601 gtaaacccat ttctgcggtc tgtttcacgg tttccgccaa ctgttgcatc cgctgtcaat
      661 acgattgctt ttgctccatt acgcttggcc acttcaagaa tatccaaatt gatcccatca
      721 tctttgctca tataaaattg aaaccattgc ggtgctttct ccccgcctgc ttctcttatc
      781 tcttctaatg tacaagaagc gtaagaactt gctgtataga tcgtcccaaa atctgctaca
      841 ccttttgcag aagctttctc cgccttcaca tgagctaagc catgagcagc aactggtgcc
      901 atgatgattg gtgcagtcag cgtttctttg tcaaaatgtg tagttgtatc gggtaattct
      961 acatctttta atacatgagg aataatcagc tgatgattga atgcccgttc attttcttga
     1021 taagtaaata agtcgccagc accactgctg atgtaaccat aaccaccagc tggaatcact
     1081 tgtgaagcgg ctatttctaa atcttccata ttgataaaat ccactattcc ttcatttgta
     1141 cctgcttgat acgttttttc catttcaatg ccttccctct ataaaaaatt gaatgaataa
     1201 tatgatagcg tttacacact ttatattact cttccgtatt gatacaggca aataatctgt
     1261 ttacatttca gtcattccag ttgttactac tctgaaagaa atgtttagaa cacaaataga
     1321 taaaaaacga tgggactttg acaaaagtcg tgtcaaagtc ccttttacga aatactgtgg
     1381 atgcctattg aaataagtgc gggttgtttc tttgtatttc aatcgtttct tgccattctt
     1441 cgtttaattt tggattaccg ttttcttcct tgaacgcata aggtcccaat ccaaaaagct
     1501 cagttagtat ttgattcacg attccatata gctcggtgtg atcggacaca tgattattga
     1561 agatcatctc attatcacca cgtttgaatc tcacattcgg gctctcatga tgaacctcta
     1621 tgcagttttc cccttttttt aactgacgga tttctgaaaa catctcataa atatcttctc
     1681 caataaaacc ttcagcaagc gccagactgt ccacaagacc gcctactgtc aactcagaga
     1741 ttatcgcttt gttggcacca agctttaatg tatagcttgt tgcttctact acgccgcatg
     1801 cattgcaacc accttctgat agttcgcttt ttctgatcaa ttgaacttct ttcattttct
     1861 gttcctcctc ttagttttct acttatgtat tttttatcac ctgacgtaag tgtattttat
     1921 cgtcacgatc acgtgattta ttcttcagag attctattta tctatctaac atatccttta
     1981 ttcttctact tttctttctt tagcatataa gagatacgca tagtaatcaa gcaaggattg
     2041 ttgatataaa aagaacaaat accgctattt tgatttcttt tgactctatt actcatataa
     2101 ataaaattta ttatacctgc tctttttgac tatatcctca tctgactcct atacttcgtt
     2161 tgtattaaaa cttaggagga atcattcatg cttacagggc taaacttatt aaataatcct
     2221 tttctaaata aaggaacagc ttttacaaaa gaagaacggg caaaatacgg aatcactggt
     2281 atgcttccaa gtactgtcca aacattggaa caacaatctg tccaagctta cggtcaatac
     2341 ttaagcaaac agaccgattt ggaaaaacgt atcttcttaa tgaatctatt caatacgaac
     2401 cggacattgt tttataaatt gatgggcgaa catttagttg aattcatgcc tgtcgtttat
     2461 gatcctgtcg ttgcggattc aatcgaacaa tacaacgaaa ttttcttgaa accacaagat
     2521 gctgcatttc tttcaatcga cgaaccagaa aatatcaaag caagtttgaa aaacgcagca
     2581 gatggacgcg acattcgttt gatcgttgtg acagatgcag aaggaatctt aggtatgggt
     2641 gactggggtg tgaacggtgt tgacatcgct atcggtaaat tgatggtcta cactgctgcg
     2701 gctggtatca atcctgcaca agtcttgcct gtatcaatcg acgctggtac taataacgaa
     2761 gaattattga ataatccatt atacttaggg aatcgtcatg ctcgtgtaga aggcgaaact
     2821 tactacgaat tcattgatca attcgttcaa tcagctactg aattattccc agaattgtta
     2881 ttacattggg aagattttgg acgaggaaat gctgcaacga tcttagaaaa atacgaagat
     2941 aaaatcacta ctttcaatga tgatatccaa ggcacaggaa tcgttgtact agctggtgta
     3001 ttaggtggat tgaatatatc aggtgagcaa ttgaaagatc aaacgatctt gacatttggt
     3061 gctggtactg ctggtgtagg tatcgcaaac atccttttag atgaaatgat ccgtcaaggt
     3121 gtacctgaag aagaagcacg ccaacatttc tatcaagtag ataaacaggg tttattgttt
     3181 gaagatacaa aaggattgac tcctggtcaa atcccattcg ctcgtaaacg ctcagaattc
     3241 actaatgctg atgaattgac aaacttagaa gcagttgtaa aagcaatcca tccaacgatc
     3301 atgatcggta cttctaccca acctggagca ttcactgaag aaatcgtgaa agaaatggcg
     3361 gctcataccc cacgtccaat catcatgcct ttgtctaatc caacaaaatt ggcagaagca
     3421 aaagcaaaag atttgattga atggacggac ggaaaagctt tagttggaac aggtatccct
     3481 gctgctgatg tggaatataa cggtgtaact taccaaatcg gtcaagcaaa taatgcgttg
     3541 atgtacccag gtttagggct tggtttgatt gcttcaacag ctacacgagt aaatgctgaa
     3601 atcatttctc aagctagtcg agcattaggc ggaatcgttg atgtaacaaa accaggagca
     3661 gctatcttgc ctccagtagc aaaaatcact gaattctctc aaacgattgc tgaaactgtc
     3721 gcaaaatcag ttgttgcaca aaaattgaat cgtgaagaaa tcacggatat caaagaagct
     3781 gttgaatctg ctaaatgggt tcctgaatat aaatctttag aagattaaga ttgttatagt
     3841 aaaagaacat acagaaactt tgtatgacgt ctaaaaagaa aaaagcgact gcggcaaaac
     3901 agcagccagc caactactgc tcttttgccg cttctctttg gcttttttca tacgatacag
     3961 aataagaaag gatctgtaaa aatggcacaa aaaacaacaa ccgcaactgc agttgaggaa
     4021 aagaaaaaag aagggttttg gtcaacaaaa attaccggcg taagtttgcc cctttatttg
     4081 atcatggtcc ttgtcctgat cattgcaatg gctttaggaa aattaccgac gaatatgatt
     4141 ggcccaatcg ctgttttggt cattttcggt aatttatttc attttatcgg aacaaaaatc
     4201 cctatcgtca aaagttattt aggtggtggc tccgtttttg cgatctttgc ctctgccgcg
     4261 attgctacat ttgggatctt acctgagtat gtagtaaaat ccacagaaaa ctttgtcagc
     4321 aatatgggct ttttagactt ttatattgct gccttgatta ctggtagcat ccttggtatg
     4381 aaccgtaatc tattgatgaa agcttctgtt cgttttattc ccgttgcact tatttcaatg
     4441 gtcgtctcct tttttgccgt aggactcgta ggtatgctta tcggaaatgg ttttgcaaat
     4501 tccgttttat atatctcatt gcccgcaatg gctggtggtg ttggagccgg agctgtacct
     4561 ttatcaacga tttatgcaaa tgttttaggt acggacgctt cttctatcat ttcccgcctg
     4621 attcctgcga cagcaatgac aaatgtccta gctatcattg gtgcagcgtt agttgctcgt
     4681 gcgggacaat caatgccaaa attcaacggt aatggtaaat taatggaaaa aggcgacctt
     4741 ggcgatggaa aacctagaaa tgtaaaacct tccattccac aattaggtgt cggtttgatg
     4801 gtatcattga ctttcttcat cttaggacaa atctgtaact attttgttcc taaagtccat
     4861 gcttacgcat tcatgatcat tatcgttgtt atctgtaaaa tcgcaaacct attaccagaa
     4921 tattacgaag atgcagctat catgttcaac aacttgattg tcaaaaactt gacagcagct
     4981 gttcttgccg gtatcggtat tgcgttattg aatctaaatg tattggcttc tgctttgaca
     5041 tggcaatttg ttgtcttatg tttgacaagt gttatcgcga tttcagtagt ttcaggattt
     5101 gtcggtcgtt tgtttggttt atatccaatc gaatcaacta ttactgctgg cttatgcaac
     5161 aactcgatgg gtggtacagg aaatgtagct gtcttatctg cagctaatcg gatggaactt
     5221 attgcttttg ctcaaatggg caatcggctt ggtggtgcca tcgttttgat catctcaggt
     5281 ttcttgatgc aattactttc ttagtcaaaa aaaatacctg atcatcaagt atcggcttga
     5341 tgaccaggta ttttttgata aaaatttaca ggattttcaa aaatcttttt tgcattttat
     5401 cggaatgata accgatgcgt tcataaaatc ggtgtgcttc tactctgtat tctgcagaat
     5461 taagtcttat tgctgatatt cctcgtcttt tcgcttcttc tacgccagtc atcaaggcct
     5521 ttccgattcc tcttttttca gcatgtttag acacagcaag tgccataata ttgaacatcg
     5581 gatcgctgaa aatcgattca taggactccg cttgtacata gccagctgct tttttagaag
     5641 taggatcttc atagaccaag aaaaaatttt tttctggctc cttcaacagt ttcttcattt
     5701 gtctcaccgt aacggttaat ggtacatcat atcctaattg ttccgcattg atttctcgta
     5761 gtgcttctgc atctcctaaa cgcatttccc gcaacatcca aatcaccagc caatttttat
     5821 ttttttaaat gaattttttt atcacagtat actccttttt tcatttagaa caatatgttt
     5881 cagtgatttt gacttgcgtt agtctagatt ctcctaatgt ttgtaagatg acaaaggcat
     5941 tgtaacaatt gaccaaaaga accacgagga caattacttg aaaaataaag gtcacttttt
     6001 ttggagacaa aaccctgcta aatcttgctc cccacaaacc tccaataaca gcagcgggga
     6061 taacataaaa caacatagat aaatcaaagc gcataaagct acttgttaaa gcaatcgtta
     6121 ccaattttgc cagttgagaa aagaaaatcg tagatagaga atatagtgtt gcttctttta
     6181 ttggcaatgc aaacatcagc atcaacaaag aaacattgac tggtccacca ccaataccta
     6241 aaaaactagc taaaaagccc agaacccccc cacatataag gtaccaagtc catgacgtca
     6301 aatgaaattt tggctgatga tgcttggtgt agaagaacgc aaaaaccaag gtcaataccg
     6361 tcaaaaaaat ttggatcagc tgcacatgct tctcgttttc aaataactgt aaaaaaactt
     6421 cgaatacaat gttgccgact actcctccaa caacagctcc actagatacc caaccgacaa
     6481 tctgccaatt cagtgatttc ccgcttgata cttgtcgcac agtcgaaaca atggacatcg
     6541 tgaataccgc aactgttgag taaaaagaaa tccctgcaac agaatgggcg ccgataagat
     6601 caagaatcgg tttgatcaac acgcctccac ccatcccgga aatagcgcca actgtgttcg
     6661 ccagaacgat caccacaaaa taaatcagac caatcatctt gtatttcctt tctcttgttt
     6721 atatctttta gcgattgtta ctcttttctt ttattataca gtaaaagaaa caaacgaggc
     6781 ttcgaaagct tttctacttt ttaaggaaat ttagtgctaa acgaaaagag gttgtgaaaa
     6841 agctgtcctg catcaagtaa taagaacagc caaacaaaaa tagctcctca taattttcgt
     6901 ttggttgaac ttattaccgc agatgcaagc ttttgaacac cgtttaagaa agaggtcgtg
     6961 agcctgccgt tcagctccga gtcacaagga acaatttcaa aaaacagctt ctcatgtttg
     7021 ttgaatattg tgacttgtga ccgaggagtt ggcaggagaa caccgtttaa ggaagagact
     7081 gtgaagtcaa cgttttgacc tgattattag agaaacaaat ggcaaaatag ttcttcatat
     7141 ttcgccgttt ttcgagcgaa tgccgagggg cagctgattg aacatcgttt atttggaaaa
     7201 agggattgtg acaagacgtt tgtcacaatc ccttttttta tatcttatta attcattctt
     7261 ttgttctatt cttcttcttc cgccatgaat gagaaaccca tatcaaagaa ctataaaggt
     7321 tatcaaaaca gcgtttatga ctaaatgaat tagagttatc tatcactatt tttcaagcga
     7381 tttaaaccaa atggcataca atatggcata caaaaacttc aataagccgt gggggttttt
     7441 aaatttcttc ttgttcttta aaatcaatga gtggagctac ataatttgaa tccacttttt
     7501 caaacgtcac tttttgcatc gacgaatgtt ttctttccca agataacgta aatagatttg
     7561 actctggact tataaagtct acttcacctt ctagtattac tttcttatgc aaatattcct
     7621 ctaataaata tagacttgct aaagcataca acacattttc caaatttgct tccttataat
     7681 ttgaagaacg accatgtttt actctgttat atattttcca ccaatctggt gtatcttcag
     7741 gccacccatc tccaaaaggt tttagtgaag tcaatgttaa agaattcata accctaacac
     7801 cattatccaa acacattaat tcgctagatt taataacagc tttaaaatca gttatgcttt
     7861 tattgctact gctatcaaat ccgcaaagtt ctttgaaaat aatctcacac tccgaaccaa
     7921 tcgctagtag tagtttttga tattcaatag agaatgtttt gaaattattc tcatcgagca
     7981 tcacaaaatc tgtggtatta ataaactcat tttctaaatg tagataatac ttccaataaa
     8041 aatttgtaaa ctctgctttg tccattaaat cacctctttt gaattataac aaaaaaaaca
     8101 cgtccacaac agacgtgttc tttgatttct acacaatcag cttgccaaaa ccatccaatc
     8161 agtcctagca tgcctgtatt aaaattgaac gttcatcatc tatcatcttt cttagtccag
     8221 catgtttgca accacaccta caattttcag tccaacaata gatttcgact agctaagtct
     8281 tgcaaaattc aggcagctaa cccttcattt actaccttaa ttatactaaa tacccacaac
     8341 gtttacaagt gtaatcattc taagaaatct gtttagctat gatcgttgta taatctttaa
     8401 acgccgttcc ttcattgatt gaaataattt tataactctt gtttttccaa gctactttca
     8461 tatcgtttgt tagttcataa tcttgatcgt atcgaataat aaacgtcaac gttccttcaa
     8521 gaatggtacc tacactagca agcacgtctt ttagcatttg tgaacgcaca ttagcccaac
     8581 attcaaatac agtttcttca ctatccacca tctgcccatc ttcatctttt acccgttttg
     8641 tctttttaaa cttgactctc tcagtcaatt catttacatt cttaatgatt ggcataataa
     8701 gcacctctca tttgttgtac taatgcttgt accgttactg gtatccgttc gctgctggct
     8761 tcttgacggt tcaaatacca atgttgagta agtaatgaca ccgccaaatc aaattgctga
     8821 taattatcca tatctttatc cgttgcgcta ctatcaatag cactttttat atattcgcct
     8881 gctgtatcaa tcaattgttg aataaagtca tcatcaatag tgtgatcgat ccgcatactt
     8941 ttttttatgc tatccaaaat taccatttta tctctcctaa tgaaaaaaag gcagtgggat
     9001 aaaccgccgc ccaatatttt tctatacttt tggtgttaca actggcgtaa actcaatata
     9061 cactgaagca ttttgatcaa ttttcttata atcgttgcga acgatcactg caagtccttg
     9121 tgagtagtaa tcgaattttt cccattgagt cgttacttga tttctacgag caacaaagat
     9181 agattgtgca atatccccca taatcatagg gaatgttcca gctttaggat tggcaaacaa
     9241 tgtatctgca atcaatacta ctggcatacc gaataatgat ttaccactag gtgctgtcac
     9301 atcgggttgt aaaatgtaac gtccatctga atctttcaat gtatctaggt ggtaatatcc
     9361 gctttggttt agaattacca ttttatttaa tgctgggtct aatgccacat tgtatagttg
     9421 tttcaaatcg tccaacgtag cagccgtttt cttagtgaat gtttttaata aatccatgat
     9481 atgcttattg tcagtgtttt ctaccaattt cgctaactga tctttgacct cttgtacaat
     9541 attcactgct gaatcttcca caacctcatt tgataaggca atcttaccag cacgagtttc
     9601 tactttataa tcaactgaag taaacatttc agcgtcaata tcaccaattt cagcaagttc
     9661 agcttttgtt gctaacactg cttgttggtt agttgctact ggatatttac cttgtccatt
     9721 tgatactgtt tttactgttg catattgagc taagttataa tttgaacgtt tcaaatcaaa
     9781 gacttcaccg attacttctt cgggaacaac tgccgctgca tttacagtag tgactccatc
     9841 acgcacttcg ccttgtgaac ggatatattc ttcataccca cgcaattctg ttttttcgtt
     9901 atcgattaaa gttttttcca tgttattact ctccttttgt gctttagaag tggattctaa
     9961 gctattgttt gtttgttttg cttggttgtt actcataaac gattcgtaag aacgcttatt
    10021 tacttggaca tttgatgaat cataagcggg aacggtcacg acactaattt cattaagtgc
    10081 tttgatttta tctattgatc gttcaattgt gccatcttct tttttgtcga atgaatctaa
    10141 tccaagcacg aacccaaagg acatagaatc aacaacccct tttgagatat tctcatacac
    10201 atcatttgaa taggtcgtgt cggttagctc tgcttcaaaa tgtaatcctg tatcatcgac
    10261 attcaatttc aacgtacctg ctttgacact agctagtggc tttgaataat cgtgtccata
    10321 taataagaac acatttgata aatccacctc ttttaatgct tcgggtgtaa tcacttctac
    10381 aaagccgcct aaatcttttg acggttgccc gaatttcaac gcatagcctg aaatagtttt
    10441 gccgtctgtt ggttgttttt cattttcttt ctctactttg ggagaatcgg ctgttagctc
    10501 agcttcttct gtcagccgtt tttccttttc ttcttcatta ttcaactggt gtaactcctt
    10561 cctgttcttt taattgatat ttctccaacg tatctaaata cgtaaagttc aaacttgcta
    10621 gtaaacgatc gccaccatcc atggggggta gccccatttt cgaccgcccc tcattaatcg
    10681 tgagaagtga ccctttgacc tgatccaata cattttttac ttttgtttca ggatcagtct
    10741 ctagtaactg atcggaatta aagcggatat tggtttcaag tttcgtatct aattcactca
    10801 caaacacatt aaagtaatga atcagcgtac tttggatata ctggagatta ctttgaacgg
    10861 tgctagaatg ttcattttca acgcctaaac gctcaatcgg tacaccaaac gccttggcaa
    10921 tttgttttgt gttccaatca ttggaattga taagcttcaa aacatcggtg tttatttcta
    10981 atgttttgta gtccattgtt tcatcaagaa tgatcgttct aagagcatta tctccactac
    11041 ttgaaccgtt ggcttcttca aacttttcac gaattgcgtt ctttgctgat ccgtctaaat
    11101 ctgacttatg aaccttcaaa atacctgacc cactgacacc acgagtaaag aaattgtgca
    11161 atgtgcggtt gccagcttgt tgaattttca gttcatcacg taacgcataa agtggtggta
    11221 atcctgttaa accatcttgg gtgaaatatt tgaagtgcaa aatatcgcta gacttcacac
    11281 gtcttttttt atcaccaatc tgataagaca acgtaccatt atctaattga gtaaccgtta
    11341 cacttgagtt aggtaataag tgaatttctt ctaccttttc accgttgcgt ttaatctctg
    11401 caaagctatt accgtttagc aacatattga ccgccaaagc aaactttaaa tgccaaccat
    11461 ccatttctga attaggtttc tcgtttagta acttcaccag ttcattatca gcttgtggca
    11521 tattgttttt gaccaattga atcggacttg aagcaatatc actagcaata attcgaacgg
    11581 ctgcaaacac atcactattt cttaatgcac gaacgcttgt aaagctggtg gtgtaatcat
    11641 ccgattggat tgataccaca tgttgtagga aaggatctcc cgttgtattt tgtctcgctt
    11701 taaaaaatgc catcttttaa cctcccttct gttctgtatt tagcatgacc gctaccccaa
    11761 taagcactat gcccagcgct aacaagccat agtagacatt tgttagtaag gtgatagcaa
    11821 ccaacacaca caccaatcca agaagtaaaa gaacggtatg aatgtaatta gaaagaaaat
    11881 tcttcacttg tataaaattc attgtctgct ttcgctcctt ccgttgtggt gaagtaatcc
    11941 attgcaaaca cataggcatt gattaatgca gctattggat caattttgtt actgttcttt
    12001 gatttattaa tctgaatgcc gttgttatcc gtttttaaaa tagcgttgtt cactgcatgg
    12061 gtgagaatcg tatttttatt gtgaataacg ttgccttcat aaacttgttc tctaaaagtt
    12121 cgggtcggaa cgtttagagt aatcgttcct tgtcttactt ctaacattgg gtagttggct
    12181 ttttcagctt tactgataag cgaattagcg ttatacgggt cataacaaat ccccatacat
    12241 tccaaatcat tttcttgaat caaatcttga ataaactgaa atacttggtc atagtccacg
    12301 attccacttt ctaattgagt aatggaacac tcaccagctt tttctagttc tcgataaggc
    12361 aaaccgtcgc gcttttcttt gtcttgaagc ccatatttgg tggctacaaa gctatgtgaa
    12421 tcacaataaa gttcgccgtt atctagcggt acgatccatg aaacgctagt taaatcatct
    12481 gttttagata aatccactcc gatataaacg ggcttgcctg taatatcttg tggttctact
    12541 tcggttgcct gccagtcttc agcaatcata tagctgtcct cactcgcttg tctccataaa
    12601 ttgaagtttt tcaccaatac agaattaagg ttattttgtt tcaaagcaag gttcacatca
    12661 tcttgaatgg ttggaatcat tacttttttg atttcttcac tttcaaaaat cggattggct
    12721 ttgatccatt tctcttgatc gtgaatttct tcgggatcgt ccaattccca tatcgctata
    12781 aagtacctgt cggcttgttc ttcgcctttt agcacacgat ctaacaataa gtattcctcg
    12841 tacataggaa cgtttaaatc aagcccagcg gtactaataa cacacaataa gccgttcttt
    12901 tgttgggtca ttcctgactt aatgacgttg tacgttttac gagtttttgc ttcgtgccac
    12961 tcgtcaagaa ttgcggttgt tggtgcaaac ccatctagcg tgctggtttc actagccagt
    13021 gccatagcga acgaattaga gggcaagtgc tgaatcttag agttcataat tttcagttgt
    13081 ggtcttaaaa acttactaga cttgaccacg tttctaagtg aattagacag catatcatag
    13141 cccaatttag cttgtttcaa agcgttactt acaaacaata cttgccttgc ttctgctggt
    13201 tcttgttcca taatcaacgc attggcagcc atgccacttg cgatatacgt tttcccattc
    13261 ttacggctca tactggtaaa cgctcgattg aatcgcctgt aattcccttc tttagtacgc
    13321 cagccataaa gactgcctag aatgaatttt tgaaatccta acatcttgat tgctttaccg
    13381 tccgtagatg gtagcaactc aatgaattta atcgctttgg tggcttgttc ttcatcgaac
    13441 acataaggga agctatctga cttagaacgc tccaaatcgc ttatatgacg ctcacacgct
    13501 tggataattt tcttgggtgc aatcagctta cctgatagga ctttctcaat gtaatcattc
    13561 atgaattcat caactctttg aacgggtctt cgggttcatc atttttaacc ttgttcaaag
    13621 ctagttttga tcgtgattct aaggtcatac ctagtgaggt ggcttgtttt ttcaaatcac
    13681 tcatagcttg tgattgaacc cgaaccgctg gattggcttt ctttactccg ttttcgcatg
    13741 tgataaacgt acctgatttt cttatctcgg cttcggctgt tttcattcga gcaaaggcta
    13801 aacaataggc taccaatgaa ccataatctg cttcactcaa tggataatct ttttttaatg
    13861 ttggtacgat acgattccat tcacttctag cgctcgctgc catccagtca gggggcgtga
    13921 tatttattaa tggttgctgc ttgaacaatt cttctctagc gtccacacgg attgcttttt
    13981 cttcacttga tatattgcct tttgtatcgt gtaatatttt agggtgtccc atgttgtcct
    14041 cctttcagac aaaagaaaaa ggaacgtaag caattaagct cacattcctt cgtttttcga
    14101 tcagaatttt tctttatcta atttatctat ataaatgatt tttccgttct gcatttgaat
    14161 ggtcacttga ccaaaatgag gtaactcaat ggtgcgctgt ttccctgttt tatcagtaat
    14221 aacaattgta tttttcaata aatctcctac tttcattata tactttttca cttgtgatta
    14281 caagtgtaat cgttatttgt aattaccctt atgccttttc acaacggtta tttgtaccaa
    14341 aatgagtagg catcgattgt cagtaagttt cacactatgc ccccttaact caaagggtac
    14401 tcttttctcg tctttgtctt tcattggctg tcttggaatt atggtgtgca tggcataaag
    14461 aacgaaaatt agtttcatct aaccgtctat tccaatcatc ttttagttca attttgtgat
    14521 ctacaacatc agctttcctt atcaagcctt cttctaggca atcctcacat actggatgat
    14581 ttaaccgata caagtatgaa gcctttcgcc atgttctact ttgatagaat tgaaaatatt
    14641 taccttcgct ttgctttctt tcttcacgct taattgccgt ttgctttgct ttatgcttcc
    14701 cacaatactt ctgcctataa tcaatcaatg ttttacatcc agcatgatta cattgttttt
    14761 taactgccat agattaccaa ccaaagcgat ctcgttcgtc agaatcatct tgttcccatt
    14821 ttgatttgta ttcaatataa ggcgaaacta tcttcaagca cgttccgtct ttaaaattaa
    14881 ctttagtgat tttatcttcc tcaaaactaa taaagtctac atcttcttga gtgtttgaat
    14941 actcaatgtg tttctcacca tcgaagtatc taatactttc catatgcata attattctac
    15001 ctccaataaa ttagttatca attcatcatc tgttagtagc aaagccaaga acttatcatg
    15061 gatgtttaaa aacaaattat cctcattcga tgtaagctct cgttgtctcg ctcgatcata
    15121 taggttaagc agacaattaa attcatccat tagctcacct gtatcatcat agttgccact
    15181 atctaccaat gatcccacta ctagcgattg acaccacgct actgactcct gcagccaatc
    15241 aggttcttct tccattatct ttaatacttc tggatcaaat gtggaataat cttctgttac
    15301 caatcccaca ctaaatgcca gcgtgttcat tagaaaccga tccatttcat ctgtatattg
    15361 aaagttcggt gctttgtttg ttgaaataat attgagcatt tactttcctc cttgattcgt
    15421 aacacgtggt aacacctacg taacaggtac ccgttaccac tcaatcccaa cggggacaag
    15481 ggttctagcg ttttggtaac aggtaacggg taaaatccag taacattatt ccccagcata
    15541 ttagctaact atttcaaaag ttttaaggaa ataaggtgtt accccgttac caaattgctg
    15601 tatcccttgg ggcagtaagg gtaaactagt aacgggctag gtgttactga cccgttacta
    15661 cccgttactt tttgtacttt ccagctcgat ttttattttc ataggcattt gacttattgt
    15721 aaaatcctcg tcgtttattt ctttttggca gttgcttccg ttcccaacca ggaatactgc
    15781 taataatcaa ggcaatcttt ttagtttctg catctgatcg accattcaat aaatcctttg
    15841 cttgtttatc aaaaacagct tccaaaatat cagcggtgag tacgctatca actaaataaa
    15901 actcttgttg catagtagct ccattataga aatgctgtaa atttttctca ttacatttac
    15961 tgtcaggata gttctgataa taagaacgtc tcgcccacgc tggagcttct tcccatttat
    16021 acgggatttc catttccaaa tatttagtga ttgcttcttt aattggattc tccatcttgg
    16081 catcctcttg atagtctttt gcaatttcta agacttcttt atcttcatcg ggactaaaat
    16141 agattcgttg tcctttatca aaaagcacct ttgcttcagc taacacttga agaaaatatt
    16201 catcctttgt tttaaacgga ttcatctttg gcttattctt acaaggcaaa ggataaaaac
    16261 ggcggtttcc tgtatcatct ttcaaatact gcccatcatt cgacgttcca ataaatacac
    16321 attgccttgc ccaagctatg acattccgac cataaggagg tctaatttta tcgatcttgg
    16381 cactgatgaa gttttttatc tgttcaattt tagttttgtt cattgaagat aattctccaa
    16441 gttcaataat tacattgcct tgaagctgca tataatcatc tttcttttca cctagcgaat
    16501 ctaatgaatc ggtgaaaaaa tcatccgtgt aaagtaatgc tggaacggta ctcttaccaa
    16561 tcccttgcgg tccatccaaa actggaacga tctcaaactt tattcctggt ttatagatac
    16621 gtgcgactga tccgactatc caacgttttg ttacttctcg tgtgtaaagg ttgtcgtcta
    16681 cccctaaaag gtcaataaac agtgtttcca gtctaggctg ttgatcccat ttaacttttt
    16741 cgatacgttc ttttactggg ttgaaaacat tctttctagc cacatttact actgctttgt
    16801 gtattttgtt gtcatcaaaa actacattgt agttttcttc aatatatgcc gttaaggcat
    16861 cctcaaaact gtcttcccat tctccagcgg tacgattgat ccaaggagaa tcttttaata
    16921 ggtgaatgta tccgctaaat tcgttataag caattgttcc agctaaattg ctatcattgg
    16981 ttaaaatcaa ttctgcattc acaacactgt tacttttaat ctgatcgtct ttattgcatc
    17041 ttaatcgtga catccaggtt ttcaattcaa tgatattgtc ttcacgctcg ctggcttcgg
    17101 gaaagtctaa aatactatct aatttatgct tatgagccat gagctttccc cctcaaatct
    17161 tttttaatca tcgatcgaat aatttgattc acttctttat cttttagcgg tggttcattg
    17221 tacgcatttg ctgtataaat caattctgct aaagtttgat tatctacacc gtgccatagt
    17281 aaccaaccgc ataacttagt taaatgatcg tttctactac cttcgccagc gccttgaaca
    17341 atcatatcta atttttttgc tgtccctgtt tttgctacgg gtcggtattg agtctttatt
    17401 tcttgcggtt tttttagcag taggttcact agccaatcgg gagctggtgc aatattattt
    17461 agagatacgt tttcaatagg ttcatatgct ctcccaacac ttcttgaaat aatcatagtt
    17521 ggcgctattg gaactccttt agtgataata tcaatcccgc ttaaactttt acctttatca
    17581 tcacgcccga agatatcagc aaatgcacct gtttcttgtt ggataattac accatcagga
    17641 attttaaaga agaaatggat tcctttacct ggtgtgattt ccgtataagt agaaggaaat
    17701 ggatcataca ttgaagcaag ttttttataa ttctcaacgc cgtttcgtgt ttcagaatgt
    17761 tgatctaggt caactaccac catttgatga tcttcaagca ttaacccaat atttctagtt
    17821 gcatcttccg tccaccattc attaatttga ttagaatcgt tagttgcatc attccaacca
    17881 ctagagcctt ttattggaat tttagttcca ggagataagg gataaattga ccatcccgac
    17941 ttttgtaatt ccgttgctgc ttgataatta tttgccaata aacctctcct cctttttcaa
    18001 aatactggta taaatcattc agacacctcc atgagcttca actgctcaag ttcgtatttc
    18061 aacccatccc gaacaaattc agcacctttt aattgattct gatactttac ccatgtatta
    18121 aatgttttca cccttgcttc ttgcatatca gtaatgttta accatgcggt taaaatctga
    18181 ttttttagct cgttgatttc tcgacaaatt attttgtgtt ctgcatgttt tttgagtaca
    18241 tacaaaactg ttagtttttc attgaatgaa tttccaaagt aggttttccc gatattattt
    18301 tctagttcag cgatcccttg attaatttcc tctaattcaa ggctatcgag ttggtttaat
    18361 agttttgttt tgtacatcta cttatgccct ccagttctta attgatagtc gtactcgtca
    18421 taagcagtga agagatataa cgctaatcct gcaaagatag ctatttttgc aattaatggt
    18481 aataagccga aaattccgcc gattaaaatg cttcctataa ttaagtttcg tttcataatg
    18541 gttccctccg attttttaat atggtataat cggaacaaag aatatcgggt tttatcccaa
    18601 ttaagttgcc tttatcctgt ccgccaagac tgttatggat aaggcttttt ctttgttctc
    18661 gatcatgtta atgctcctaa gttgtctgca attcagcaga acgattataa attttctcac
    18721 tcactgaaaa ctgcaaccca tatttttctt taacagtcat taattctact gtctcatcta
    18781 aaataggttc acgatcaacc aacatttcag gagtcatatc tttctttttt accattttgg
    18841 aatgaccata aatagttgat acagctttat tggctatcac attcgcttta atgtagtcta
    18901 ctggttttgg ttcagtaata gcgtggctta atttagtcat tgcttctttt tggtgttctt
    18961 tgtctagcat gcggaatact tgaaagcctt caagtcctgt ggactggcgt agttctttga
    19021 tgatgtcgaa aatccagtct tgaaatgcct cggcttcttt tttacggctt ttgaatgcca
    19081 tgcggtaaat attttttttc gttgatgatg tttacatctt gtgttctgcc caatgaatcg
    19141 atgaccttac tagtagtaac cccatcttta ggcaaagagt gaatggctct agtaacctgt
    19201 ttaagaccta acgcttccgc aacatctttc gccactgccc accattcatc attaatatcg
    19261 acaaatctta taatgtgtcc gttccaaatt tcagttttca ttcaacgtcc tccagttcaa
    19321 gccctagcaa gctcgctaac aactcaactt gctgatacaa aatttcttga tactcttcaa
    19381 tagaaagtcg ttctttaaac tctgcttgta ctaaatcgtt caagccacgc aatactccgc
    19441 ttaccgttgg ttcttgtggt agcaattttt gatagtccat ttgttcgtac aaacattcaa
    19501 acgtttcttc tagcgctttg ccttccaagt ttgctaattc tgccgctgtg tcttctgtaa
    19561 gaattgttga taatactttt tcgattgctt tattttgtgt cgattccatt attatttcct
    19621 cctattaatc cctttgcccc cacggcttgc gtttattttt ggtattcttc cataaagcga
    19681 tcacattcat cttgtgaaat tcttacgact ccatcaacta taatcaactt taaaccgtta
    19741 ggaacatatt tctgcatcat agtattgtat gaaacgttca tatacttagc agcttgtgcc
    19801 ttgttcatat attttggaaa ctggtacttt ttttctaata atgaaagtaa cgttccttga
    19861 gtttgctcta cttgttgaac aactcgatcg tcaataattt taaaagctgg atcatcaagc
    19921 gtgagtttgt caatttttaa ttccatattt atcccccctc gttagcatac atttctatac
    19981 aaagatttta aaaaaatgca agaggctctt gaatacattt ctatacctct tataaactca
    20041 atataccatc ataccttttc atttgcaaga attttaacat acttttttga acttttatgt
    20101 ttcacacata tttaaatcgt gatatagtag agaaaatata tgaatggtgg tgaaaatgtg
    20161 gctagaaaaa aataccccga agcagtggag acaggacaaa gaattagact ggctagaatt
    20221 gaaaagggac tctcaatgga acaacttgga ggtaaattat ccccaccggc cagtaaaggt
    20281 gccgttagta attgggaaaa tggctataat cttcccaata acaccaggct taaacaactt
    20341 tcaaaggtat tagatgtatc cactacctat ctattaaacg gatcttatac attaagagat
    20401 atgcatatga tgcccgaaat taagcgaaat gtgcttgaaa agcaattgaa aaaaactatt
    20461 gaaaaaaata actctataat tgattctaat ctttctaatg ctatcaataa catcgaagaa
    20521 gataacctga ctgtctcaca gaagatttat ttaacaaacg caataaaata tcttaaaaca
    20581 ggatctcgaa ttgaatttcc tgacgggagt accccaattg cttatctcgc agctcttcta
    20641 aatacgcttt tacgatatga ctcattaatt aatgattcag aaaaaaatac agatgagaaa
    20701 aaagagtatc aagaatttta tgaaaatgat cttctaaaag agttcacagc tcttgttact
    20761 gagctaaata aacactattc aaaataataa taaactgcct cctccaaccg cccccacggc
    20821 ttgctacact atggagggaa aactattatg gcaacattca agcaatatga aactaaaaaa
    20881 ggtaaatttt ggctctatga agcctatctt ggaatgaaca aaatgactgg caaacctgat
    20941 aaggttcgta gacgaggtta caaaacaaaa aaagaagccc agcttgcctt gtcacgcttg
    21001 caagtggact acgataaaaa cggtattaaa aaagcgaaca acgaaacgtt taaagaagtt
    21061 tatgacttgt ggctagaaac atataaaacc actgtccgag aagccacctt catgaaaact
    21121 gaaatcaagt ttagaaagtg gattcttcca aaatatggaa atcttcgtgt gaatgaagtc
    21181 acggtaaaaa aagcccaaca aattgtaaat agctgggctg aaactactga ccaatacaag
    21241 gtacttcatt caacttctaa gcgtattttt agctacgcta tcaatcttgg gattattgag
    21301 actaatccac tagacaacgt attaatgcct aaaagaacca ccactaagca taaagaaaag
    21361 gtcaaagttt acagtaaaga acaactgatc accttgtttg attacctaaa cagcaaacct
    21421 gaaacttatc gaaacgactt tgataaaacg ttactacgct ttctctttta tagcggggtt
    21481 aggatcagtg aagcccttgc attgaattgg tcagacattg attttcaaga aaatacggtc
    21541 accatcaata aaacactaag ccaatccaaa aatggctata aaatcagtga tcctaaaact
    21601 gattgtagtg ctggggttct tccactagat gaaagaacaa tttctatatt aaaaaaatgg
    21661 cagattaatc agcggaaata tatgctgaca cttggtgtaa ctgatccgac tatgattttt
    21721 tgtggtatct ataaagaact aatcacacac cacgctattt atgcaagatt gattactatt
    21781 tgtgaaaaag ctatggttcc atttctcggt gtgcatgtag caagacacac tcatgcttca
    21841 atgctcttgg acgctggagc tactatggta gaagttcaaa ctagattacg gcatacaaaa
    21901 attagtcaga cgatcgattg ttacggtcac ttggcaaaag aaacgaaaga aaagactgtt
    21961 gaaaaattag tacaacactt aaatattgac tagatggcat acaatatggc atacagtaaa
    22021 aaataaaaaa aggagaaacc ctatcatatc aaggtttctc ctagctttat agtctattct
    22081 tcttcttccg ccatgaatgt attgaatact tcttcaatca tgtcccattc tgcgtctgtt
    22141 tcgatttgtt ctaactcgcc ttctgttcca tcttcgtttt cgatgtatgc ataagcttgt
    22201 aattctacat cttcatcttc tgaaacacca gcaggatata aaagaacata gttacgtcca
    22261 aattcttctt gtccgtcaac tgttagtagg atttcatata atgtttcatt tccttggtca
    22321 tccaccaatg tgatgtgttc gtgtccttca tggtcgtggg aatggttatg ttctgtcata
    22381 agattacctc ttttctttta ttattaaaat aattgcttac ctgagccgtc taaataattt
    22441 tgtaagatca tcacagctgc taatttatcg atgacttttt ttcgtttggc tcttgaagta
    22501 tttgcctgct ctactagcat acgttctgcc tgaacagtgg ttaatcgttc atcttgataa
    22561 tcaactggca aggagaatag ttctttgatc ttttctccgt atgacatgga agcttctgcc
    22621 cttggtccga tggaattgtt catattttta ggtaatccaa ctacaaaccg gtctacttca
    22681 tattgtgcta ctaattcctt caaccgatca aagccaaact cttcttctgc ttcattgatc
    22741 cgaatgatct ctactccttg agctgtccag ccaaaggggt cactgatagc aacacctact
    22801 gtcttagaac cgacatccaa gcccattact ctcataaatt cactccatga tttgagaggt
    22861 agtccttgac aattacttcc atgatctcat cgcgttcgtg acggcgaatc aaatttcgag
    22921 catcacgata acgaggaatg taggacgggt ctccagaaag caagtagccg acaatctgat
    22981 tgattggatt gtagcctttt tcttccaaag cccgataaac aatcgctaat gtttcgctca
    23041 cttctttttt gcgactatcg tcaaaaccaa aacgtacggt ttcatctgta aaacccatga
    23101 ttctacacct ctttcccgca aggtaattcc agcttacctt ctacaacctt attttactcg
    23161 aagaaaggga aaactacaaa caaatattcc aaacttccga ataaattaag aaacactatt
    23221 tgtatgtttt tttccttttt tctgtagctt tatcaaaagt actcttttca taaagtatac
    23281 gctatatttc tttgaatgta tgtttttaca caattttttc ataatattca taaaaaattc
    23341 gaatagctgc tactaatttt ttgtttttgt tgcttgtcct gtctcataat tgatcgtgta
    23401 gccatcttga acattgtaga taaagacatt gaattcaatt tttttgtctt caatgctttc
    23461 tgcttccaat tgcactcccc tggctaccag ttcattcccc tcaaaatgag gagtgacacg
    23521 gtagcgtaca tgatgatttg tttctttgat atatgccgca atatcatttt cgtgagcaag
    23581 catgtatgga gcattcaacg aacgtgtccc tgtcatcaag tttttaatgt tgttattttg
    23641 accagtcagc tggaaaccaa ttaaatggct gcgattatat aaccattgcc cgtcacttaa
    23701 tttcttttgt ttccaacctg tcgggtcaat atacaaaggc tctctctttt cagtagggaa
    23761 caaatctttt ccaagcatag cattggcttg tcctactctg ttcaatttat caatatttga
    23821 atagctttcc catgttcctt tggaaaggct aagatcctct tttgtaaatt ccggctgatt
    23881 cccattgatt tctatttctt gatgttttcc atcatattct ggcacatccg ctacttgaga
    23941 agcttgtggt gtggaatcaa aaatagttgt aatctgctga aagatatctg aatctttttg
    24001 tgtggtggaa acaccgaatg cccctgcaat cacagcagcg acgatcccca cgatcgcctt
    24061 ggttgttttt ttgctcattt ctttactcct ttactaacag ctccctaaat cttaacatat
    24121 gttcccctat aaataaatac tagaaagaaa tagaaacagc aaaaaataaa acctgtttta
    24181 agatggctta aaaatacaaa aaagagacgg attcctcgtc tctaatcagt caccactcta
    24241 tctgtaaggt atttattatt attcaaaaat tttcttcata ctcaagacaa tacactgatt
    24301 tcacaaccgc ttggtaaacg gtgcgcaaaa gcttgcatct gcggtaataa gtccatccaa
    24361 gttaaaaaca taagaagttg tttttgcttg gctgttctta ttacttgttg cagagcagct
    24421 ttttcacaac ctattttaag cgggtgacgg gaatcgaacc cgcgacatca gcttgggaag
    24481 ctgggatttt accactaaac tacacccgca atacaaaaac agtatacgcc tcttttattc
    24541 cttcctcaag tttttttatt ctttacgctt ctggtatgtt ttgtagtaaa ataaaactaa
    24601 tcaatcaatt attggagaag atgctatgac gggaaaagaa ttagatctgt tgctggacac
    24661 ttgtttactc gctgggaaaa tcatgatgga aagcaatgcg gagatgtatc gggtagaaga
    24721 tacgatgagt cgaattgctt tagcttctgg aaatttccgt ttggtcagct atgtcactca
    24781 aaccggtctc tttattggtc ttgatcgtac ctcgaccatc cgaatggaac aaattaccaa
    24841 ccgttcgatt aatttagaaa aagtagtaaa agtaaatgat ctttcacgta aatatgttgc
    24901 ttcagagcta acattagaag aactttactg cgaactgcaa gcaatcgacc gagaccgttc
    24961 tttctttcct gtctggttgc aaatcgttag cgcggcagtg atcagtggaa caattatggt
    25021 gttatttggc ggaaagatga ccgatttacc tgtgacttta gtcattggag gattgggata
    25081 cgcagcttat ctatatagtt tgaaattttt tagaatcaaa tttttatcgg aatttttatc
    25141 ttctttattg attggcatag ccgctatcta cagcgtacgt tttggcttag gaagcaatca
    25201 ggatctaatc attatcggat gtgtgatgcc tttagttcct ggagttcaaa ttacgaacgc
    25261 tatccgtgat ttgctagctg gacattatgt ctcaggagtt tctcgcggaa cagaagcgat
    25321 gatgactgct acgatgatcg gttttgcgat tgcttttatt ttccagcttt tttattagga
    25381 aaggaacaca agtatgggga cgatatttat tcagttttct tttagttttt tagcgactgc
    25441 ggcatttgcc gttattacaa atgtacctag gcgttcattg atttgttgtg gtctttctgg
    25501 tgcttttggc tggatgatct actggatctg tgttcaaata ggcggatctg ctgcttttgg
    25561 ttcattgctt ggttctttag gagtagcatt catcagcgat cttttctcta aacgtttgaa
    25621 aatgcccgta acgattttca atattcccgg gatggttcct ctagtccctg gtggtttagc
    25681 ttatcaagcg gttcgaaatc tcgttactga atcctatcga gaagcggctc attatgcggt
    25741 ccaagcaatt atgattgctg gagcaatcgc tttaggtctt gtattatcag aagtctttaa
    25801 ccataacatc cgtaatttca aagtaaagcg tgacgcaatc atgatgaaac gaaaaaaacg
    25861 gctttttaaa taaacgaagt gtaacaaaga aaaggttgtg aaagagacgt tcagccttga
    25921 gcgatgacaa aatatctcac aaacattgcg acaagtaacc gcaggagcaa taagaagtaa
    25981 ttatgagtat taaaaaaagt tttgtaaaaa tagcttctca catttttaca taaaattgac
    26041 ttaatactga gaaactgact tttgaacacc ctctatctgt aaaaaagggg ctgcgacatg
    26101 atttttgtca cggcccctct tctttattca aattttttcc aaaacgttcg ttgataataa
    26161 acgatccata gagcggaaag tattagaact aaaccgatca caggaatatt cactaaccaa
    26221 aatggataaa acaaagccaa cattccgtat aagacgataa gaataatact gatgatcaat
    26281 gaacccatca tagttgcgac taaacccaaa cttcctgaac ctctgttaaa taattggtta
    26341 atattggtcc agttcagcag cagcaaccga taatctctag cgaaataacg tagtgacaat
    26401 aagtagcagc cgaataaaga accaaatagc aagctaggga taaaaaacaa aggcagctga
    26461 aaagacagtc cgcttaataa tgcgatccca ccagttaaaa aactctgcaa tatccatccg
    26521 aatctgaact tttcttttaa atattggttc atagagattg gcaaagaacg gataaacaga
    26581 aaattttctt gatccaaaga aataagattg ctgataaaag aagtctgatt aactgttaag
    26641 aaagccaatg cgatccctac caggaaaaca acaccgatta acttattatc taaatcagtt
    26701 aattttattt cgcctcctag ggcaaaagca agaataaaaa tgattggagt taacaaggaa
    26761 gaagaaagaa cttgcataat caaattaggt tcttttacta attgagcatt gtaactaaat
    26821 aaaagctgat gcacattttg gttcttttta tgggttcttt ttattttgaa ctcactgttt
    26881 gaatcagtca gttgctctgt aagctttggt actatcagct gttttacagc aaggaaaaat
    26941 cccagagccg tgatagctag tattccccaa cccaataaac cttgttgaga aagtggctga
    27001 ctggcagcat catagaatgg caataatatc gaaatcggat gccgatctgt taactcattt
    27061 tcaatagtcc ccgtttgatg attcatccac atgattccag caaatgcgat cagcatcgag
    27121 ctgccaagca agatactaga aactgttttt ctatgttttt taaacactgc tgttcgagcc
    27181 aaaccaaaaa caatcaaact agccagacaa aaaagaataa tcaaaaatag agaaaacaaa
    27241 aggattgaga taatgatagt aagcaaaatc cctagatcag ctcgccatcc ggttaaaata
    27301 aacatgacta gaagcggaaa aacaaaagga atgatggtca aagcaactac caaaatcttt
    27361 gctgaaaaaa cctgttcttg tccaaaaggc agaggcaaaa atacttgcag gtcatttcct
    27421 tcaaaaaaga tattataaat gactgatata ctttgagtta aacctaacat accaaaaagt
    27481 gccacgtaat aagtaaagaa acctggcaat ttaacaaagt tcatagcaaa catagcaaat
    27541 ccgtaaatca gtaaaaaaat cagccctgaa aaaagatttt gagacaaaag atagatagtt
    27601 aatcgctttc ccttttttcc tttctctctt gctttattcg tgagctgtgg attaacatat
    27661 aaaagattaa ctcgaattaa ttctaataat tgtcgcttat acatacggtc catctcctgt
    27721 cgcttgcctt ccagccattt tcaaataaat cttttctagc gtttcatcag gtgagccatt
    27781 caataattca ctaactgccc cctgataaat caattcacct ttcttcaaaa tagccagttt
    27841 atcgcataac tgttgtgcgg tatccaatac atgtgtagaa aaaatgactg tttttccttt
    27901 tgcggcatga gccttcatca tttctttcaa atcaaatgct gcttgaggat caagtccttg
    27961 caaaggttca tccaataccc aaatatctgg atctggcagc aacgtgccga tcaaaatcgt
    28021 tttttgacgc attccatgtg aaaaacttgc gattgtttca ttttgatgac tatacatatc
    28081 aaaaagcgct gtcaattctg ctaaacgctt ttcttttttt tgtgtgtcta attcataggc
    28141 agctgaaatc aagtcccaat attctccagc cgtcaattgt aaaaaaatat ctggggaatc
    28201 aggcacataa ccgatttttt gtttgatact caatcgattt tccgtcaatt tcattccatc
    28261 tactaaaatc gttcccgatg atggttcaat aatactaact aaacttttaa tcgtagttga
    28321 ttttccggca ccattatgtc ctaaaaatcc aaaaatttcc ccttgtctta tcgagagaga
    28381 caagtctttt aatgcttgtt ttttcccgta acttttactt acattgatga attcaatcat
    28441 ttctgtactc cttttgtttg ttattacttt ttattgtacc cttcgttatt ggtggagtaa
    28501 atgtcaaaaa gagtgcataa caaaaaagga tagaaacgac taggctgcta cttgggttgt
    28561 tctcttctac aggaaaacac tcttctaaca ggtaagatat gagtctttgt tttctttaaa
    28621 atgattcatt ttctatcttt tcttgcataa aattctttag tttatcaata cttctctttc
    28681 ccatctctag ttgttctcca tttgcaaatg ttactatttc gtttactctg ctaatagatg
    28741 taatgttttc agtattaatg atataagctt ttaaatcttt acataaatac tcatattcga
    28801 gtgatttttt atatttttta attgtgccgt ttacgagaat ctcttcatct ttcaatacta
    28861 ggcctatttt atttttataa cctggcatgc tcattagata aaggatttca tcgtaatgga
    28921 tatagtgatc gctattacca taacggacag ttgtccacct ttttttcgta gcatgttgaa
    28981 caggatagtt ttctttttct ttcaataagt aactttggat gcttttttta tttttttcat
    29041 aagtgaattc ttttatcaaa taaccactag gcgtaatctt tcgattaata acagttattg
    29101 ctttattcgg atgagacgtt agataaacaa ttttacactt ttcattcttt tctctaagca
    29161 tttcgcctag ttcgataccg ctataatagg cgttcaaatc gatgtctagg aaaaaaatat
    29221 ctgaggaata gatttcatta tttttaatga attcaacaaa ttgtataacg ttcaatccct
    29281 gaacgatctc aaatttccaa ggacttaata aaattctgga ttcttccaaa atttctacta
    29341 gcattttttc aaaaaccaaa ctatcatcca aaataaatat acgcgttacc ataaaaagta
    29401 cctccactcg atattttact atcaaaatca tttcatacaa cttttcaaca tacatgttag
    29461 gaataaattg taattctctt cacaatcttt tccaacacct ttgaaaccga tatcaaatac
    29521 tttcaggatg ctgcttctaa aataaatatc aaacaaatga atacatcatg caaaaaaagc
    29581 cagacaaccg acgtccttgc gtgtcagctg tctgagctat gtttatttat tttgttcttt
    29641 taaaaagaac gatacacata ctgatttttc ggagcagaga ctttctcagc gtttgtaaca
    29701 actacagatg ggatttcacg cttgaatggt tgataatagt ctgattggat ggttccttct
    29761 attttatacc attcatcatt tttaaccgtt actccttccg gcatatgcgt caacaaacca
    29821 aagactcctg aatctgccac acaatggata atgccgaatc ggaacaagaa gatatctgta
    29881 ttgctatcgt tcggtgtttg gtaaacaaat ccttcatagc tgattttttt gccaatgaat
    29941 tcgctagggt aattataaat tagctccata acttctaaat agttttcatc tgtgatcttg
    30001 atagtttgct tatccccata cttttctttc aactcattca tttggtctaa gtagtctgat
    30061 ttgttgaaat aaatactggt atccggcttt aagtattgtg tctgcatctc cggatcccct
    30121 actgattctt tacttactgg gaaattaaat cctttggctt ctacgatcgt agtgtcgaga
    30181 ctaactgttg gaaacaacgt ccccacgatt actggcaaag ctagcagtac ataagcgatt
    30241 ccacgttgat aaggttttga caacccatgg tcatgatcgt gctcgtgtgc cttttcttct
    30301 gcttttccgt ttttgaccca caaatacagc tgaactaaag ccaaaagagc agataaaatc
    30361 attgaaagaa tagctaagta gcgataatgg acattgatat attgatcgag tttgccagaa
    30421 acttgcaagt acatcatcaa ttcgaaatac ccagataaaa tcaaaaaccg cagcatattt
    30481 tccctcctaa ataaataatg tgaatccaat aacgctaagg gcaatcagtc cgatcagcga
    30541 taaaataaag cgtcctgtaa aatatcgttt catcatcagt agatttttga tatcgaccat
    30601 tgggccaaag accaaaaagg cagctacagg tgctgtgccg aacagactta acaaagaaga
    30661 tcctataaac gcatctgctt ctgagcaaag agacatcgta aaggccaata acagcatgat
    30721 gataatggct aaaatctttg ttgagccgag cgttagcata attctagttg gtaaataagt
    30781 ctgcatcgca gctgcgatta atccgccaat gatcaaataa cgacctgtat caaaaaattc
    30841 gtcgattgaa tgtgtcaaca catgcccagt ttgatggatc agctgatttt ttggttcatt
    30901 cttctcactt tgttcttctt catggacatg atgatggtga ttttctgcta ctttagacgt
    30961 gattttttct ttcaatacag cgtctttttg aaaataggca agccagacac caatcacaag
    31021 ggcaacaaaa aagctgccta tcacccgcca gcttgccatc tgccaagaat tgccaaatgc
    31081 gataaaagtg gaaaaaatca cgattggatt gatgatcgga gcagtcagca taaaagcaaa
    31141 cgctgtgtga actggtacgc cttttttaac aaattgatga acgatcggta cgatgccgca
    31201 ttcacatgaa ggaaagaaaa atcctaagat cgaaccagta aaaatagaga agatacgatt
    31261 ttcaggaagc catctcttca cacgttctgg ggtcaaaaat acttgtaagg cgcctgagat
    31321 aagacagcct aataatacga aaggtaatgc ttcaataacg atcgataaga aaatcgtact
    31381 catctgcaaa accgaatttg gaataaaaga aaacatgagt ttcctccttt ttatttctag
    31441 ttcattcgct ttgcaaatat acgcttttat tcaaaaaaaa caagttgctc tgtaaatttt
    31501 tacacaactc ttatttttta ccaaagcact tcaattgact ttttctgtta ttcccattaa
    31561 attaaggtct catacatatc acttctatca taaaagggag aataaaaatg aaacaaacca
    31621 ctaacttgac tgaagttcaa gacatactgc aacagtcatc cgttgccgtc atttatcttt
    31681 cgatgcctaa ttgcagtgtt tgtcacgctg ttcgtccacg actagaggaa cttctcacac
    31741 attatgatat tccggcactt catttggatg catttgaaac accagaagta gctagtaaat
    31801 ttgaagtgct gactgcgcca gttgtcctga tttttcatca aggaaaagaa gtctttcggc
    31861 aagcacggtt catcgacttt aaaaaaatcc gttatctact agatgaactg acagcagaag
    31921 atgattccct ttcttatgaa gaaatcttcc gaacaaaata atcgttgtcc aaacagaaaa
    31981 aagcgattga acaagtgaaa gttttgcctt catttgttca atcgcttttt atttttattc
    32041 tgctgtattt tcggaatgcg catttgcgtc agaatgcaag aaatagatca aggtttgcaa
    32101 ttcattcgtc aaatcaacat tttggatcaa tacatctgac ggagcattca atcgagcagc
    32161 ggtaaagttc aagattcctt tgattcctgc ttccgttaac tgattgacta cttcttgtgc
    32221 tctttcagcg ggtatcgtta aaattgctac ttcgatttgt tggatcttga tttgttctga
    32281 catatcttcc attggataaa cggggatacc gtctacgatg cgcccaacga tttcctcatt
    32341 cacatcaaaa gcacaactga tacgtatgct attactttga tggaatttgt attttagtaa
    32401 agcacttccc aagttcccta caccgatcag cgcaacattt gtcaattgat cgtcgtttaa
    32461 tgtctttgca aaaaagtgca taagatcttc tacatcataa ccatacccac gttttcctaa
    32521 ttcgccaaaa taagaaaaat ctcgacggat cgttgcacta tctacttgaa cggcttcact
    32581 taattcagtt gaagacactt ttttctttcc agcattattt aaaatcctta aatagcgata
    32641 atacaaaggc agtcttttag ctgtcgcctt tggaataata tgatctttca cgaaatgacc
    32701 tccacgtatt gtctaattac atctttgatt tctccatcat agcagtattt ataggaaaaa
    32761 atcaattcca ttgctcagat attgtgaaat tttattcttt attcatttat ttatcatttc
    32821 tgcaaatctc gcagtataat ggaatttatg gtagactact aattgaaaaa tagtttttta
    32881 tttgaggaga attcacaaag tagaaaagag gattccatga tattattaca agccaatcag
    32941 attgctcgcc attttggtgc agaagtctta tttgaaaaca tacatttaga aatcagtaca
    33001 ggcgctcgtg tcgctttagt tggcagaaat ggcgctggaa aatcgacttt attaaagatc
    33061 attgctggaa ttgaagcacc tgatgaagga aagatcgcta aaaataaaac agcgactctc
    33121 ggatacctcg ctcaggacac aggacttgat tccaatgaaa cagtttggaa cgagatgctg
    33181 aaagcttttg aacaagttag acaaatggaa gagcggatgc gcgagctaga gattttcatt
    33241 agcgaaggta cgccagacac acctgcttat agttcttatt taaaagaata cgaccggctg
    33301 caacacgatt tttcagatcg aaacggctat ggttatgaaa atgaaattcg ttccgtattg
    33361 catgggttta aattcgattc ttcattttat gatcagaaaa tcgatacttt atcaggcgga
    33421 cagcgcacac gtttagcttt agctcgcatg cttttgcaac accctgacat tttgattcta
    33481 gatgaaccaa cgaaccattt agatatcgag acactttcct ggcttgagaa ttatctgcaa
    33541 agctatactg gtgcattatt gattgtttcc catgaccgtt attttttaga taaagtagtc
    33601 aatgaagtct atgaattaag cagaagaaaa atgcgccatt acaaaggtaa ctattcgaaa
    33661 tatctagatt tgaaagcaga acagttagca agtgaatgga aggcttatga aaagcagcaa
    33721 acagaaatcc ataaattaga agacttcgtt gctcggaacc ttgttcgcgc ctctaccaca
    33781 aaacgagcgc aaagccgcag aaagacatta gaaaaaatgg accggctgga tcgtcctcaa
    33841 ggggatgaaa aacaagcaaa ctttctattc agtatagaaa agccttctgg aaatgtagtc
    33901 ttgcaaatcg aagatgccgc tatcggatat gataatgtca ccttatctga accaatcaat
    33961 ctagatatcc gtcgtcaaga agcgattgct ctagtaggtc cgaatggtat cgggaaatcg
    34021 acgttgctga aatcaatcat tcaccagatc ccttttatcc gtggaaaaga aacgctaggg
    34081 acaaatgtca ccatcggcta ttacgatcaa ggtcaagctg atctgcatac aaacaagacg
    34141 atcctagcag aattgtggga tgagcatcct accactccag aaaaagagat ccgaagtgct
    34201 ttaggtgctt tcttattttc tggcgaagat gtagaaaaac caatccctct gctaagtggc
    34261 ggtgaaaaag cacgggttgc tttagccaag ttagcgatga acaaagaaaa ttttttgatt
    34321 ttggatgaac caacaaacca tttagatatt gacaacaaag aagtattaga aaatgcattg
    34381 atcgattatg acggcacact gctttttgtt tcccatgacc gatatttcat caatcggatc
    34441 gcgacaaaag tcgtcgaact ctctgaaaat ggcagcaaag tctatctagg agactatgat
    34501 tattatttag agaaaaagca ggaagaagaa gaaatcgccg aattgttggc acaagatgag
    34561 ccagaatctg ctcctgctcc cacgaacaaa tctgattatt accaaagcaa agaacagcaa
    34621 aagcttatcc gtagccttca acgaaaaatt actcaggttg aagaagaaat ggcgcggatc
    34681 gatgaatgga tcgatcagtt ggaacaagaa atggtcgcgc cagaaaacct ggaagatcac
    34741 gtaaaactca atgagctgaa ccaagattta gaagctgcta gacaagatca agaaacaaaa
    34801 ttgacggaat gggaagaact aagcttggaa ttagaagaat atgaaaatta acgaaaaaac
    34861 caaaacagaa accattcatg ctgttttggt ttttcttttt ttattttatc aaacaaaaat
    34921 tccatattta cctttttcac caataagaag accaattact agtcattctc actaaagctt
    34981 ctaaataata gtaatcaccc caaatacaag gtgtatttac cccattattt ttgggcttat
    35041 tataaacaga ctgtgttaaa aagccatctt cttcttccgt tgtagcatat ctttctttca
    35101 attgtcgcat aattttccaa acagcagact ggtataagtt cttttctgtt ttgtctaata
    35161 gacctgattc tattaattct aataatccac aaaccatgat caccatacta gatgtatctt
    35221 tttcttctct gctagaatca tcaaagatca aatcccaata acaaatggta tcttctggca
    35281 accgattcat aaaataattg gctaatattt tgcttaaatc aaaatatttt tgttctttca
    35341 aataacgata acttaatgca aaaccgtaaa tcccccatgc ttggcctcta gcccaacagg
    35401 aattatcact ataaccttga tgcgtacttc catatcttgg ttttccatct ttgacatcca
    35461 tataaaatgt atgataagtt gaaccatctt ctcttactaa ataatctgct gcattttgaa
    35521 tatgagcctg agcagctttt ttatattttt gatttccagt ttcttcactc gcccaataca
    35581 ataatggaag attcatgcaa caatccatga tcattctacc ttgttgtgaa ggatcactag
    35641 gatctcccca agcttgtata actcctgcct tctcccaaaa acgctgaagt aatgtttctg
    35701 cagcatcaat tgaagcttcc ttcatttttc gatttcccgt tattttataa tctgctacgg
    35761 ttgataaaga atacaaaaaa ccaagatcgt gatgattagt gataatttga cagtcaatcc
    35821 tgtggataaa atctatatct gctttttcag ctgtttgttg aaataaagga tcacccgtct
    35881 tctcaaataa caaccaatta attcctgtcc aaaatccttc tgtccaacca atattgtctc
    35941 ttaatggata acgtcctttt ataggacact cgcttgggaa ttgatactga ctgttactga
    36001 tacgtttgat taacctctcc gtgtgtctgc gacaacgctc gatctcatta ttccattctt
    36061 tttccattaa ttctttataa cattcattta tccatttttc tggatgtatt atctcttcaa
    36121 acatcacttt atcaagcatt tccccaccag cctttagcat aattttagtc tttttttatt
    36181 gtttttattt tggatagtta gcccggttgt cccatcaaaa tcaattttgg gacgattgtt
    36241 ccatacttct aaactataat cccgatcttg atgagcaacc actcctgttc cgagccaatg
    36301 ggttcctttt ccaaatgtac cctctaatcc aggaataaaa gtgttttccc atgtcatcaa
    36361 gtttgtattg ggcaaaccca taatagctgt ggattttcgt ttaatagtat cgtcacttaa
    36421 acagataata cctgaaaagc cagcttcact caccctatag ttttccttgt cttcttctat
    36481 gattattcct tctttctcag gagaacattc aatagcaaac cctgtctcat atagaacata
    36541 ttctgtatct aattctactt tgtgtacgcg aatctgccag ccttcaaaag gaataagcca
    36601 agttctgatt tttgcctgta aagtaggttc ccatgtagag gcaagtacct ctttcttaca
    36661 tacaatgtct cgtacattat ttcgaacgat gaactgtcca taggttttga tgctctcatt
    36721 cttaaaactg gtcgtgatat atgtgtccgc tcgctgaatc cctagcattg aatccattgc
    36781 catttctgct ttcaattgat tcgctcgcgg tatcgaaaaa ccaaattgac tagaataagc
    36841 aaattttaaa tatttttcat tggtcaatgt atggaaattt ggccctaatt gtcccgcatt
    36901 caaaaaaaat gtatgtccat tatcatgttg tatgagcaaa ttggcttctg aaagaagttt
    36961 agttccttca cgaataggca taggcatttc tttagccgtc caatactcat ggtcttcagg
    37021 tagcgccaac aataaaaaaa tcttattcag ccataatgga gataacgtac tattataggg
    37081 ttcagtcaat gtcaattgag ggtaggtata accaatattc aggatacctt tttcatcaaa
    37141 tatttctttt tgcatccacc atcttatatt ccgattgact aaccccttga tttcacctaa
    37201 tttaaaaggc aaaagatcgg cccacaacat agctgaccaa aagcttgaaa ctgcaaaacg
    37261 ataaatcatg cttcgaccaa aaggcacatt tgcaccatct tccgcaaaaa aatgaatata
    37321 gtctctagaa aaatcaatag ctcggttctt atatatctgg ctaatgggct tttctggttc
    37381 tagtacgcta taaatcaaac cataataatg aaatgcaaaa ggattataat aatcttggcg
    37441 acctcttgaa ctgtctcgat accagccatt ttgaagataa caattttcta tattatcaaa
    37501 tgcttctttc agtgctgatt ctttaactgg ataaccaaat ttttggataa ttgttccgac
    37561 aattatctta aaaaattgcc aattaccatc tgcacattca tattcaaaaa tttgcgagaa
    37621 ccaatgaata atctggcttt tttctcctgt atctaatttt ttccataata attgttcatg
    37681 atgatataac gctaataaca ttgcgggcat ttctaccata cgctggtctc tttcatgtat
    37741 ttctccccaa taatcgggat gggaaggatc tgttccagct tttattcctg atagaattaa
    37801 tttcaaccat cgttcatcta attggtcaat tgcgggcccc gctccccata aaacccgaga
    37861 gaatccttcc attcctgcaa ttttatttcc atatcctacc ccttgatgta tataatcaat
    37921 ttgtgcgcca cttgctcgat aaaacggctg gagtggttga tttatctttt taaataagtc
    37981 aaagtaatcc tgtctggtcc ttaatagtgg tactggatgt ttcattgtat tttctcctct
    38041 ttttactacc aaatagctaa ttccgactgt tctaatcgaa gtaagccttc aataaaaaaa
    38101 taatcagaat agatcagtgg cacattataa gtcagttctc tatggtatgc ttctgctccg
    38161 cctccaatga tcccatcttc atccatattc caatttgcat agtgcttttc tgtcttttgg
    38221 agtatattga tagcagcttc atgatacatt tttgatcgta cagaggaaac atatcctgct
    38281 aattccagaa gaccgcatgc agcgcatact ccagcactgg tatcaatatt cgaatctttt
    38341 acagcaaaat caatgagagg aatataacca gttttttcga ttttctgaat aaaatttact
    38401 gctatctttt ctgctatagc tagatagtac ggattttttg tgtaacgata acttaacgcg
    38461 aatccatata aagcccatgc atttcctctg ctccaacaag aattctcatt gtatccttgc
    38521 ccgccaagta accgaatata tttccctgat tctgcatcaa attctgcgat atgcccggtt
    38581 gatccatctt tcctcactag atacttagct gttgtatctg catgctgccg agcaatttta
    38641 gagaacctcg gatcaccagt ttccctcgaa gcccaataca gtaatggtaa attcatcata
    38701 ctatcaataa tcatccaacc aggtttatgg tcattccatg ctactaaata gttccctgaa
    38761 atattatagc gtccagcaag taccgtagct gcatgtaacc ctagttgtcg actatgtttg
    38821 ttttgagact gttgataatg tgcaatagcc gatggtaaga ataaaaaacc tacatcatga
    38881 tgaacgtctg aaaaatggta cagggcagat tctaataatt gttcttgttg tattgctgcc
    38941 tctttgaact tttctcgttt tgtcttgtga aagagctgcc ataaaatacc actccaaaaa
    39001 ccattggtcc accagtcgat tcctctgtcc tttattacgt ctgtatattt tccgttgtaa
    39061 gaaatatatg gaattttatt ccccattctg tctaattccg catctatctt ttcagaagct
    39121 acattcaaaa tttttcttga ccattccttc gtctgttcat tcatggatat cccgccattc
    39181 ttttaatttt tatgaatgtg gagttgctcc tagaacgaac tagatggtta acattcgtta
    39241 ttttttttac ttatttgcag ctccaatgtc attctcctta aatttagact gcgcccacac
    39301 ataaatcaag accattggga tcactgaagt tgctaaaatt agcataattg cgccataatt
    39361 aattggctca cctgtactag aaaccgtcat atttttgata attaagggaa ccgtatattt
    39421 atctttatct gaaagcatga ctaatggaaa tagatattga ttccaacttc ccataaagat
    39481 aagtaaacca ctagtaataa tcgtaggtga taaaatcggt acagcgattt tcgtaaaaat
    39541 cacccactca ttggcaccat cgattctggc agcctccatc agtgctgtag gaaattgact
    39601 gctatattgt cgcatcataa acactgaagt tgtactggca atcgaaggga tgatcacacc
    39661 tgcataagta ttcgataatc ctaaacgact cataatgtaa aataaaggaa tcaatgtggt
    39721 aaaaaaaggc accatcctag atagcataac tgtattgaac aacagtttat tccccataaa
    39781 acgatacttt gctaatgcat aacccgccat tgtagaactg gctgtagcta aaactgtact
    39841 gattacagca ataacaatcg aattccaaat aatcaaggga taattatatc tcgccatgat
    39901 ggcttgccag ttttttaata gcatatcccc aaacttgaaa ttgattccgc cacttaaaat
    39961 ttcttgatta ctttgcgttg aagctacaat catatataaa tatggcatca aaaatattaa
    40021 ggcaccaaac acaataatga cgtacgtaaa aattctgctt tgtatctttt gtttagtcat
    40081 ttttatcacc tccgaattta aattgaatag ccgataatat aacagataca aacaccatcg
    40141 tccaggcaat agcagaggct tttccaaaat caaccatttc aaaacttgtt ttatataaat
    40201 tgactcctac gaccaaagct gaattttctg gtccattgga agtcccaaag aatatatttg
    40261 ggatattgaa attacccaag ccattgatag tggctaaaac tgtggccatt aaaatgattg
    40321 gctttagcat ggggatcgtt aataaaaaga attgccgaaa tttcgatgct ccatctattt
    40381 cagcactttc gtatatctct ttagaaatcc cttgaagacc agctaaaaat aaaatagtgt
    40441 tatatcctac actaagccaa atcatcgtga tgatcattga tattcgtatc caaaaaggat
    40501 ttgttaacca ctgtacaccg ttaattccta gcgcattcaa aaatccattg aataacccag
    40561 tcggattgaa aaaagtcatg aatacggaag ctacagccac cgttgatgta atggttggaa
    40621 tataatagac agttctaaaa aatccttttc cttttaactg tgctgaattc aataaaacag
    40681 caaagtaaat agctaatagc atcgttattg gaattgatcc tgccatgata atcaaaacat
    40741 tcgtgtaaga tttaataaac aatggatctc ggaagatagc tagataattg tcaaatccaa
    40801 caaattcaaa tgagtagcca attttcataa aactaaaagc aaacgagata atgatgggaa
    40861 tcaaaatcgt cacaataaag aaaataacaa aaggtgtgac caatccataa gcactttttt
    40921 tatgagacgt atctgttgct tttttcttgc tgttctttat tgtcttgctt ggtaacgaag
    40981 attgcatcat cgttaagtcc tcctaatatt ttttaatcac cagttaattt tacgccgtac
    41041 ttatgagcaa aattttctgc ttcttttaga tatgaatttt caaaatcacc tgtttgccaa
    41101 tagttatatg cagcggtagt caaataagac gtagcatctg aataagtggc tggtaaaaca
    41161 gtatttgatg tattttcatt gattttattc aatagttcat agtatttttg tcctccttag
    41221 tagtcaaact ttttctcagc tgcttctgtt tgataggcca atgagttaga tgtagccacg
    41281 cccagctcca gtgcgttggc taagcattct tcatctgtca gcataaatgt aagaaattgt
    41341 tgtgccactt gtggattttt tgcatcttta gggacataaa aacttgatcc tcctgatact
    41401 gcaccttttc ctggattttc ttttgaaaaa ggaatcagtg gagccatgcg ccatttgtca
    41461 gatgcatcag gaaaattcaa agacatattc gtagcatacc agccgccagc aacaaacatt
    41521 gcagattctt gaaatgcttt ctcagcatct tgtgcaccgt agaaatgtac aatatctgag
    41581 tcgatcattt ctttgattaa ctttgcagca tgtttcgctt ctttagtatt cagacggata
    41641 tttccttctt catcaagcaa agattgattc tgctgggcta gcatgttgat aaacaattct
    41701 tggtccccag attctggcaa ggcaattcca aaactaccag ttttttcttt taatgctttt
    41761 gccacctgga tatattcttc ccaagaactg atttcttcaa aatctacacc tatttcagca
    41821 aatttttttg gttgataata acaaagtgct ggggtaaaat cactagccca aggaataatc
    41881 gtttcattac tcgtttgttg acgcaaaata ttcaattttt gatcataaaa ctgatcgcca
    41941 tatttgtcat aaaatccata ttcatcagca ctataaaaag catcttgaaa tttttccagc
    42001 acacctgctg ctgaagtgtc tgccatggag ataatatccg gcatatcttc gtgtgttacc
    42061 aattttgggg tgatcatttg tactgttgct gttcccgaag ctacattcac aatttttaag
    42121 tcaatatttg ctccagtttt gcggttatag atttttgcag cattttcaac atagtttgtc
    42181 agtttgccgt ttgcgacata tacttctaat gtagtggctt tttttatcat tggatctgcg
    42241 atgtttgctg ttacttcttc gttagttttt ccacatgcac ttaagctgaa taatagggta
    42301 atgtttagca aagctatcac caatttgtat ctttttttca tgtctatccc ttctttcttt
    42361 tcaagttctt atataaaac
//
LOCUS       DAFLWQ010000017        39751 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.018, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000017 DAFLWQ010000000
VERSION     DAFLWQ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39751
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.018"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..840)
                     /locus_tag="L1V16_000904"
     CDS             complement(<1..840)
                     /locus_tag="L1V16_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1275261.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMD"
     gene            complement(1064..3004)
                     /gene="thrS"
                     /locus_tag="L1V16_000905"
     CDS             complement(1064..3004)
                     /gene="thrS"
                     /locus_tag="L1V16_000905"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBN1275262.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3341..3520)
                     /locus_tag="L1V16_000906"
     CDS             complement(3341..3520)
                     /locus_tag="L1V16_000906"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HBN1275263.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3567..5390)
                     /gene="cadA"
                     /locus_tag="L1V16_000907"
     CDS             complement(3567..5390)
                     /gene="cadA"
                     /locus_tag="L1V16_000907"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBN1275264.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5668..7947
                     /locus_tag="L1V16_000908"
     CDS             5668..7947
                     /locus_tag="L1V16_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1275265.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8040..8687)
                     /locus_tag="L1V16_000909"
     CDS             complement(8040..8687)
                     /locus_tag="L1V16_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275266.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(8866..9585)
                     /locus_tag="L1V16_000910"
     CDS             complement(8866..9585)
                     /locus_tag="L1V16_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1275267.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9716..10867)
                     /locus_tag="L1V16_000911"
     CDS             complement(9716..10867)
                     /locus_tag="L1V16_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBN1275268.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11084..11824)
                     /locus_tag="L1V16_000912"
     CDS             complement(11084..11824)
                     /locus_tag="L1V16_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1275269.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11828..12151)
                     /gene="rsfS"
                     /locus_tag="L1V16_000913"
     CDS             complement(11828..12151)
                     /gene="rsfS"
                     /locus_tag="L1V16_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBN1275270.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12208..12801)
                     /gene="yqeK"
                     /locus_tag="L1V16_000914"
     CDS             complement(12208..12801)
                     /gene="yqeK"
                     /locus_tag="L1V16_000914"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBN1275271.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12785..13435)
                     /locus_tag="L1V16_000915"
     CDS             complement(12785..13435)
                     /locus_tag="L1V16_000915"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBN1275272.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13445..13756)
                     /gene="yhbY"
                     /locus_tag="L1V16_000916"
     CDS             complement(13445..13756)
                     /gene="yhbY"
                     /locus_tag="L1V16_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBN1275273.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13772..14881)
                     /gene="yqeH"
                     /locus_tag="L1V16_000917"
     CDS             complement(13772..14881)
                     /gene="yqeH"
                     /locus_tag="L1V16_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HBN1275274.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(14878..15405)
                     /locus_tag="L1V16_000918"
     CDS             complement(14878..15405)
                     /locus_tag="L1V16_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HBN1275275.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15585..16370)
                     /locus_tag="L1V16_000919"
     CDS             complement(15585..16370)
                     /locus_tag="L1V16_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBN1275276.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16363..17232)
                     /locus_tag="L1V16_000920"
     CDS             complement(16363..17232)
                     /locus_tag="L1V16_000920"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBN1275277.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17233..18612)
                     /locus_tag="L1V16_000921"
     CDS             complement(17233..18612)
                     /locus_tag="L1V16_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBN1275278.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18620..19039)
                     /gene="fabZ"
                     /locus_tag="L1V16_000922"
     CDS             complement(18620..19039)
                     /gene="fabZ"
                     /locus_tag="L1V16_000922"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBN1275279.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19064..19540)
                     /gene="accB"
                     /locus_tag="L1V16_000923"
     CDS             complement(19064..19540)
                     /gene="accB"
                     /locus_tag="L1V16_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBN1275280.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19543..20778)
                     /gene="fabF"
                     /locus_tag="L1V16_000924"
     CDS             complement(19543..20778)
                     /gene="fabF"
                     /locus_tag="L1V16_000924"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBN1275281.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20797..21534)
                     /gene="fabG"
                     /locus_tag="L1V16_000925"
     CDS             complement(20797..21534)
                     /gene="fabG"
                     /locus_tag="L1V16_000925"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBN1275282.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21546..22463)
                     /gene="fabD"
                     /locus_tag="L1V16_000926"
     CDS             complement(21546..22463)
                     /gene="fabD"
                     /locus_tag="L1V16_000926"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBN1275283.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22570..22794)
                     /locus_tag="L1V16_000927"
     CDS             complement(22570..22794)
                     /locus_tag="L1V16_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBN1275284.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22847..23809)
                     /locus_tag="L1V16_000928"
     CDS             complement(22847..23809)
                     /locus_tag="L1V16_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBN1275285.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23819..24259)
                     /locus_tag="L1V16_000929"
     CDS             complement(23819..24259)
                     /locus_tag="L1V16_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1275286.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24565..25530
                     /locus_tag="L1V16_000930"
     CDS             24565..25530
                     /locus_tag="L1V16_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBN1275287.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(25587..25817)
                     /locus_tag="L1V16_000931"
     CDS             complement(25587..25817)
                     /locus_tag="L1V16_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HBN1275288.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(25903..26790)
                     /locus_tag="L1V16_000932"
     CDS             complement(25903..26790)
                     /locus_tag="L1V16_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBN1275289.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(26879..28102)
                     /locus_tag="L1V16_000933"
     CDS             complement(26879..28102)
                     /locus_tag="L1V16_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBN1275290.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28119..29165)
                     /locus_tag="L1V16_000934"
     CDS             complement(28119..29165)
                     /locus_tag="L1V16_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBN1275291.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(29329..31056)
                     /gene="ptsP"
                     /locus_tag="L1V16_000935"
     CDS             complement(29329..31056)
                     /gene="ptsP"
                     /locus_tag="L1V16_000935"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBN1275292.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(31056..31322)
                     /locus_tag="L1V16_000936"
     CDS             complement(31056..31322)
                     /locus_tag="L1V16_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HBN1275293.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            31801..34035
                     /locus_tag="L1V16_000937"
     CDS             31801..34035
                     /locus_tag="L1V16_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1275294.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            34183..34503
                     /locus_tag="L1V16_000938"
     CDS             34183..34503
                     /locus_tag="L1V16_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBN1275295.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(34708..34932)
                     /locus_tag="L1V16_000939"
     CDS             complement(34708..34932)
                     /locus_tag="L1V16_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HBN1275296.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(35130..36710)
                     /locus_tag="L1V16_000940"
     CDS             complement(35130..36710)
                     /locus_tag="L1V16_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBN1275297.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(37111..38487)
                     /locus_tag="L1V16_000941"
     CDS             complement(37111..38487)
                     /locus_tag="L1V16_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBN1275298.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(38615..39733)
                     /locus_tag="L1V16_000942"
     CDS             complement(38615..39733)
                     /locus_tag="L1V16_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1275299.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
BASE COUNT        11276 a         8564 c         6879 g        13032 t
ORIGIN      
        1 atccataaaa tattcttgga ttgcttctcg tgtttttttc actttttcgc taagcttttc
       61 gtttttagcc atatagaaat aaaaaatgat atcgatcgta gcaaattggg ccaaaagtga
      121 attagttgcc gcacttcgat tcgtgatttc ttttggtcta gatgtttgta cgagtacatc
      181 ggctatcttg ctaagcgggt tatttccaaa ttgcgtcaac gcaatgattt cgatattcat
      241 gcttttcgcc agctcggcta atgcgactac atctgcactt ctacctgagt ttgaaacaag
      301 ccaaagcact ttctttttct cattgctgac aagttgcggg agcaagacgt ggatatcttt
      361 ttcaaaaatg attggcttac cgacacgaga ccatttttgc agaatatctt ctactactaa
      421 agaagaggcg ccaaccccat ataaaaaaac agtctctgcc gattccaaac actctacgac
      481 tttttggatc gtttcttctt ctagaatatc tactgtttct tttatcgcta cttgtgcatt
      541 gttaccaagt ttgtttttga tagagtaaaa ggactcattt gcttctatat cactaaaacc
      601 ttcatcgatt ccagtctgta gttctgttga aatcgtgatt ttgaagtccg tcagactttg
      661 aaaaccgatt tttttggaaa aacgtacaac tgtcggcgca ctcaacccgg aagcttctgc
      721 taattcatta gctgtcattg tagggacctt ctcaatatta ccgataatgt agttggccaa
      781 ctttttttct gctgaagaat aatcttccat catactttca atacgactaa ttacgctcat
      841 aagttcctcc acccttttaa tgatagtcta tgtaagtata ccatatcaga cccttattca
      901 cggtcgtata ctggataaaa aacaaaaaaa caatccgccc aacagaatat cttatcccat
      961 caatcccaca gattctattg agcatctgtg tctttgagga atacctgtta tctattgttc
     1021 ggattgcttt ctatctacta cttttttaca ggaaatttac ctattagttt tctctgctgt
     1081 aatttttgac ttctgcttcc atagcatcaa taaagatatt caaatcttct acagctgttt
     1141 ctttacttcc ataacgacgt acgttcactg ttgcatcttc caattccttg tctccaacaa
     1201 ctaattggta agggatcttt tgtgtttgag aggcacgtat cttatagccc attttttcat
     1261 tacgatcatc aacttctaca cgcaacccct tcatttgcaa acgttctttg atttcataag
     1321 cataatcgcc atgtgcatca acagaaacag ggatgattgt tgcttgtata ggtgccaacc
     1381 atgttggaaa agcgcctttg tatacttctg ttaaataagc gacaaaacgt tccattgtag
     1441 aaacaattcc gcggtggata actactggac gatgcgtatt ttccccgtct tctccaacat
     1501 atgtcaaatc aaagcgctct ggcaataaga agtctaattg tatagttgat aatgtttctt
     1561 ctgtaccaag agctgttttg acttgaacat ctagttttgg tccgtaaaag gctgcctcgc
     1621 cttctgcttc aaagtaatct agttctaatt catccatagc ggctttcagc attgcttggg
     1681 ctttttccca cattgcgtca tcatcaaaat atttatctgt attgtttgga tcgcgatagc
     1741 tcaagcggaa acgataatct gtaatattga agtcagcata tactgccacc atcaattcaa
     1801 gcgtacgttt aaattcatct ttgatttgat caggacgaac aaatgtatga ccatcattca
     1861 acgtcatttc tcgtacacgt tgtaaacctg acaaagcacc tgatttttca tagcgatgca
     1921 tcattcctaa ttcagcgata cgaattggta attcacgata agaatggatc gtgtttttgt
     1981 agaccatcat gtgatgaggg cagttcattg ggcgaagaac aagcatttcg ccatctccca
     2041 tatccattgg cgggaacatg tcttcttgat aatgatccca gtgtccagat gttttgtaca
     2101 actcaacatc tcccattatt ggtgtatata catgttggta acctagacta acttctttgt
     2161 ctacgatata acgttcgatc gtgcgtcgga ttgttgcccc ttttggaagc cagaatggca
     2221 aaccagaacc tacttctggg gaaaccatga acaagtcaag ttcttttcct agtttacgat
     2281 ggtctctttc ttttgcttct tcacggagac ggatatattc tttcaaagct ttcttgtcaa
     2341 aaaaggctgt cccgtataca cgttgcatca tttgattgtt tgagtttcca cgccaataag
     2401 cacctgccac tgataataat ttaaatactt gtatacggcc agtggatgga acatgtggtc
     2461 cacgacacaa atcgatgaat tcgccttgtt gataagcagt aatcacttct tcttctggca
     2521 attcactaat cagttctact ttgtacggat cacttgcaaa aatttctaat gcttcctgtt
     2581 ttgaaagaac acggcgttcg atcggcagat tttctttgac gattttcatc atttctgctt
     2641 cgattgccgg caaatcttct gcagttactt ggttttgtcc attatctgta tcgtagtaaa
     2701 accctgaatc gatagctggt ccaacgccaa agtggatatt tggatagagg cgacgcatgg
     2761 cttgggccat caaatgagct gctgaatgac ggactaagcc aagtgcatct tcatggtctg
     2821 gtgtgatgat ctcaatactt gcatcttcct cgattggacg agtcaaatca acgagttttc
     2881 cgttcacttt accagctaaa gctttttttg ctaagctttt tgaaatgctt tcagcaattg
     2941 ccaatgttgt tgttccagac tcaaattctt tgactgcacc atctggaaaa gtaattttta
     3001 tcataatagt ttcctccttg aaatgttttg attgatcaga tcatcaagct gaaaaacaaa
     3061 aaaatcctag catctcttga aaagagatac taggacgaaa agttcgtggt tccacctaat
     3121 gttcaaacgc aaatgcgttc ctcaagcgtt gtaacggtcc gaccgccctt gcttcaacaa
     3181 gggtttcgaa agtggtcatc ctttggtttt ctcctggaaa agtttcagcc tagcttttcc
     3241 tctcttatcg aagactctca aattcagttg gctttctcat caatcaatta tgtgtttatt
     3301 taaccactaa taaatagaaa aatcaagtgg gaaactaaac ttattttttc cattccccat
     3361 ttacaccgta tgttcctttt ttcatctcat tgatgatgac atggatgtgt tcttttggtg
     3421 cctgcgtgtt tttatgaaca gcttccgtga tatctttcat catattttct aattgttccg
     3481 gactgcgacc ttctactaat tcgacatgta cgaatggcat aatgctctct cctctttctg
     3541 atcgttcttt tttcaactcg attctatcat actatgtttg tcttgggtac tgaatcagga
     3601 aaaatggctg gatctttttt tgctctcaag gcactcaaaa tagagaccgt atccacgact
     3661 tcttgcaaaa cagctccgaa taatgcgggg attagtcccg tacttgcaat taacatcaaa
     3721 aaaatacaaa taaagatgcc aatcagtaca gactgtttcg ctattctcat cgtatctctt
     3781 gaaatcacta ctgcttttgc tacacgcaag agatcatctt tcaagatgac cgcatctgca
     3841 ctttcactag cagctgtaga accatgagcc cccattgcaa taccgatatc tgcagcagca
     3901 agtgctggtg cgtcattcac gccgtctcct accatcgcaa caggtctttg atctttaggg
     3961 atactttcta aaatggtcag tttatcttga ggcaagctac gggcatgtac agaatctaat
     4021 tggacttttt ctgcaatcgt ttgagcaatg gcagatccat ccccggtgat catcatcaaa
     4081 tttttcacat caagttttct tagctccttg attgtctttg ctgcttctgg gcgaatctga
     4141 tccgaaaata ggatcgttcc tgcaaaagat cgatcaattg ttacatagat tgctgtattg
     4201 gacgtttcta tttcttcagc tgaaacaaaa gaggcacgtc caatctttac ttcatgatta
     4261 ttgactactg cttggattcc ttgaccggtc acttctttca gttgactaac aggatacagt
     4321 tggctgtttt tcacgttgtt cactaacgaa cgagctaaga tatggctaga ttcctgttct
     4381 gcactagctg catacagaag tagctcttct ttttttattc cattgactgg ctgaatcgcc
     4441 tctacttcca atatcccttt ggtaagcgtt cctgttttat caaaagcaat cgtttttgta
     4501 cgtgcgagct tttcaatcgt tgttccagtt tttacaacga tcccgttttt acttgaacgg
     4561 ctcattcctg caactaaagc aatgggcgca gctagaatca gtggacaagg tgatgccact
     4621 accagtacct cagcaaatcg taaagggtct tttgagaacc accaagaaat accaccgatc
     4681 aaataagcaa tcaacgtgaa agggactgca taacgatcag ctaaacggac aaatcgggca
     4741 ggcttttctt ttgattcttc gactagttta ataatcattt gatactggct gtctgcggca
     4801 cgtttttcag cgatcatttg gatcgatccg tctccattta aagaccctga cataatctga
     4861 tctccaggtt tcttggtttc cgggcgggac tcacctgtca aagaagattc atcgaccgaa
     4921 gattctcctt tggtcactcg accatctgcg ggtacaagtt cgccaggctt gactagtaac
     4981 tggtcatcaa tatttatttc atcgattact atatcctgca attttccttc tttgaatcga
     5041 tgggcaattc ttggggtgtt atctaacaaa gactgcagtt ctttacccgc tcgtttattc
     5101 gcgtaatcct ctagactatc tccgcccgta agcatgatca atatcatcaa actagcccag
     5161 tattctttga cggctaatgt tgcaaggatt gcggtaatcg ctaatacatc tacgccatat
     5221 cttcctgaac gtaacgtctt gatcatttcc aaaaacatca agaaggcgag aatccctcca
     5281 gtaaatgcga caatcgcaaa tgcaagggcc ggctggtgaa aaacaaattc acttaataaa
     5341 gctatcccac caataagcaa agtaagtaaa aattttttga aatgtgtcat tgttttttct
     5401 cctcttttat gtgacttaga gaggttagta ataaatttcc agctgcctct ttcatcttaa
     5461 gcatagtcct tgactagcac tttttaaaac aataggcctt aattgaaaac aactatcact
     5521 atcagcgttt ccaaaattca tcagttctac aaacaaaaat attcagcaag gattactttt
     5581 tcgattcatc agttaaaaag tacctttttt cgaaaaacta tgctatactt ttaattcgtt
     5641 atttacggcg gaaggagcaa acatgcgatg aatgagaaac aactagaaca aacgcacgtg
     5701 gatgaaacga tcgaactaat ccagatcgaa caaaatatgc tggatacaaa acaacaagaa
     5761 ttgactcagg aaatgaatca ttcgacaaaa gacacagcta atcacaagat tcgagctggt
     5821 tccaatgaag ctttttatga atctgctgtt gaatatcgcc aacatgagca ggaattgctt
     5881 ttgaaatacc atactcttga agcacagcaa aaacgcctgc aaacgttgtc tgtcatgaaa
     5941 gatagtcctt attttgcccg tatcgacttt aaagaagacc gtgaaacaga aacattatat
     6001 ctaggtatcg cttctttaag agatctggca gaagaaacaa tcgttattga ctggcgcgca
     6061 ccaattgcca atctttatta tgaaggtgag attggtcccg cattttatga aactgaaaca
     6121 gatagaatag atgtcgatct gcagttgaaa cgacaattta aaatccaaga aggacgtatt
     6181 ttatctatgg tagatacgtc ggaagtaatc aatgatgact ttttgctaga gatattggat
     6241 gaatcatcaa gcaaccatat gaaaaacatc gtctctacga tacaaaaagc acaaaatgca
     6301 atcattcggg acacaacaag taaagtaatg ctgattgaag gaatcgccgg aagtggaaag
     6361 acatccgctt tgcttcaacg tattgctttt ctgttgtatc ataatcgcaa gtggctcgag
     6421 gctgaaaacg ttcttctatt ttcacccaac catttgtttt ctgattacat ctcgactgta
     6481 ttgccttcat taggtgaaag cggcgtgcct acacagacat tcaaaaatta tttggtgcag
     6541 ctgctgccag agttttcttt actagatgaa cagcaacaag aaagtggttt tttgctaggg
     6601 gaaaaagatc cgatacaagt gatgaaaagc ggattgacct tagtcgatca gattgatcgc
     6661 tatatccaag gcatcacaaa ctacggtccc ttgttccgtg atatgaaaat aaatggccgt
     6721 acgatcctat caaaggaatc gattcgccaa tggtataaag aaacaaatga acaattacct
     6781 ttacatcata gactttctct attacaaacg aagctcctga aaaaattagg cggtctgcaa
     6841 aaagacgaaa cacgtcagca atgggtcaaa gatctggcgg aagaacagct ccaagaacta
     6901 tacgcaacag atccaaatct tgaatataca gaacaaaagg agcgttcatt acgtaaaaaa
     6961 ctggccaacc aaatcgtacg taaaagattc cgtcgaatcc atcgagggat catgaattat
     7021 caatttgtca atataacgaa acaatatctc cactttctac aaactgtgcc actttctctt
     7081 ctaacacgac ataaaatcag cgagaccagg tggcaggaac atttgacaac tgttcgtaca
     7141 cacttgcgtc aaagagaatt gcgtcaagag gatgctgtac tattcttttt actgatgcgc
     7201 cgaacatatc cagtgacggt tacacacaaa gctcgctata tctttattga tgaaatgcag
     7261 gatttcgcac catcacaagt ggcattgctg caagccttgt tcccaaaagc aaatttgact
     7321 ttctgtggag atctaaatca aaatgtcttt ggaaatgaaa cgatcgttgg atcattggaa
     7381 gaccttttcg tggaccgtga agtcactcgt ttccaattaa cgacaagcta tcgctccaca
     7441 aaagaaatca ctgattttgc taatcatttt attgtgaaag aacatcaagt agaaacaaca
     7501 gcaagaaaag gagaccttcc tttgctcatc caaggaacaa cagatgatat caaattgaat
     7561 tggttagcag ataccattcg aacgactcag ggaaaagccc ggtattggcg tacagcaatc
     7621 atagctaaaa cacaagaaga atgcgaagct ctttatgctc aactgccaga cgagttgaaa
     7681 caacaagtcc agctgatttt aaatgagagt gactttatga agcgttccat tattttactt
     7741 ccagcctttt tagcaaaagg tctggagttt gaccgagttt tcttgtggga tgtagatgca
     7801 gaacattttt cttctcagca agacaaattg atcctttaca ccatgtgtac acgtgcgatg
     7861 catgaattga ccctttttac ctccaataat gaaagtcctt tgttaaacaa tatggatatt
     7921 tcatcttatg agaaaaaagt actgtaagta aaaagacaac tgctatcatt aatgttagca
     7981 gttgtctttt tatttacaat aataattgca gaaaaagtaa ttcaatcatt taaggtcatt
     8041 tattctatat ataaatccaa atctgtttca ggatatttta atttgacaag cgaaataatc
     8101 attttcagtt cttccatgtt ttctggatat tctgggtcaa ataccttgct atgacggcca
     8161 atcccgccat tgtcgatcaa tcggtaaatt cgattccatt caatgaattg gtcaattgat
     8221 tggaaattgc tgattggata gccgccacaa tccaaaatct ctgatacacg aaatgctagg
     8281 tatgcactat cgatcacttt attttttttc gtgtctatct tctcatttct ttcgataaga
     8341 attttttcag gacgatgttt caagctccac tctaatagta gaaagaaagc ctccatccga
     8401 tactcttctt caaataaccg aaaggctgaa tcagaacgac gaaaaagcag cggaatcaga
     8461 taattttgtc tataaatcag cattggtgcg cggtccacca tacactctaa ataacggttc
     8521 agataccctg taccgacata gtttcctaat cgatagcctt caacgccgaa tcttgcgtat
     8581 ttttgcgcta attttgaaca atcagttacg ttcacagcta actcttctac tttgcggtaa
     8641 ccgcttaaga tacgttcaaa aggttctaaa gtgatttttg cttccatatt cttccccgtc
     8701 catcttccac atacttcata tcatttcaca tgatacttat gctctcatca taccacaggt
     8761 tgaattagaa aagaaaataa atcacacaaa aaagcaagac aatctgttag tgagattgtc
     8821 ttgcttttcg aaaaagactg aatacttttc gttaaaactg gttgcttagt cttctaatgc
     8881 cacattatgg aacacatgct gtacatcttc tagatcttcc agtgcatcaa tcattttttc
     8941 aaatgtttct tgatcttctg gagatagtgt tacctcgttt tgagggatca tttggatctc
     9001 agcgattgaa aaatcagtga ttcctttttc ttttaatgct tcttgtatac tatggaaatc
     9061 cgctacttca ccgtaaacga tgatttgtcc ttcttcttcc attacatcgc gaacatcgat
     9121 gtctttttcc attaggtatt caaggatctc gtcagcgtct tctcctgcaa aagcaaagat
     9181 tgctgtattg tcaaacatgt aagaaaccgc tccggaaaca cccatgttcc cgccattttt
     9241 cccaaatgct gcccgtacgt ctgctgctgt tcgattcaca ttgttcgtca atgtatcaac
     9301 aatcaccatt gagccgcttg gtccaaatcc ttcatagcgc aattcagagt atgtttcatc
     9361 tcctgcacct tttgcttttt cgattgctcg gtcaataata tgttttggta cattataagt
     9421 tttagcgcga tcaatgacga aacgtagttt ttggtttgca tgcggatcag gatcacctga
     9481 ttttgctgcc gcgtagattt caatcccaaa ttttgcataa atccggctat tattagcatc
     9541 tttagcagtt ttctttgcta cgatatttgc ccatttacgt cccatatttt cacttcgctt
     9601 tctgatttga tagtttcata acgcaaaaac gtcctgttcc attatacttg tgaatcacga
     9661 ttctgtgaag ctttttttct ttcttccttc attcttctca tttttagtca attatctata
     9721 ctcggattgg gatttgcccg aaattctgtt ccggaatatt gcctcccaat tgatagattt
     9781 gatcacttct aactaacagt tccgcttctt gtgcctcttt ttttccgatt cgggaataaa
     9841 tagaaatctc ttttttttct tttaagaatc ttcttccagc atcggtaaat ccaagtagtc
     9901 gaagataatt tttattttgt tggacaggaa tctcttgctt tttgatattc agcaagacat
     9961 aacaagataa tcgttggatc cgtgtccatg tatatctttt tgtttttacc tttgacacaa
    10021 aatcctcaaa actatcagca gttgcagctg ctgttttcat gcgcgattct attccttcgg
    10081 tcatctgata gatatctgtc agttccagca aagtagaaga taacaaccga taacgcaaat
    10141 acggccaata agattcccaa gtctgcagcg aacaagttga aagatcttct tctgtctgag
    10201 gcggcacaag tccagctatt ctttttcctt cttctaacgc atggcgaatg gctgttgcac
    10261 tggctatcct ctgatctgtg atgatttttt catgatagcc tgcactttta cgtcggatcg
    10321 gatgtaattc catagggtgg acatacttgg cattttcctt tgcataactt aatcccaaga
    10381 tatgatttgg cgaagaaaaa tcaagcgtaa tatcgggata cagactgcga aaaacctcag
    10441 tcattttttg cggataacta tacgtttgat cagacagttc ttgaaatgcc tcttctatcc
    10501 tatcttgatt ctcttggaca aagcgtccga aactgctgta atcaaacgaa gtctcttctt
    10561 ctgttccaaa acacaaactg tcacagtcca gtgtttgcaa gatttttact gcacctttag
    10621 caaaatagtc agctgactga accgcccatt cgacgggaag ctccactact aaatccacac
    10681 cattttgtaa agcttcattc gcgcgatgcc atttatcgat gatagccggt tcgcctcttt
    10741 gcaaaaaatt cccgctcatt acagcaatga cgacctctgc tcctgttatt tttcgtgcca
    10801 tttccacatg atagcgatgt ccattgtgaa aaggattgta ctctacgata atcccgcagc
    10861 ttttcatgcg catcctcctt catagttatc gataaaaaag aaatagagac aagtaaaaaa
    10921 aggcaaaaat cggaaaaaat acccgaacta tataaactat tctcgcaaac acaatacttc
    10981 tgcgacgaaa agctgcactg caagagcaat gcctatatcg ttcggatata taatttatgt
    11041 tgaagattta ttcttttctt gttaactcga gcaggcaaaa ccgctagtct ttgtatgcta
    11101 caaagaacca gcgctttgat ttctctgatg ctgcttcgtc tgtaaaatca gaaaatgctt
    11161 cgactttcga aaagccgctg ttttccagca ttcttaaata actttccaat ggataggtac
    11221 gctcttgatg tagttcatct tcacgaataa atcgaccaga cccttcttgt tcttcaacga
    11281 aaaaggtaag aaaatgttcg atgctgtgtt tctcgcttcc tggataacta tcccacaaaa
    11341 aagcaaaatt atccccttga taatgatagc tatattctgg aaaaacctca tctacttgat
    11401 aggtggagtg tacgtcaaat aaaaatcggc cattttcttc taacgcttga tagacttcat
    11461 caaacacttg ctgtacctct tgtctatttt tcatatagca cagcgaatca gaaaaacagg
    11521 taattgcctg atattgtccg atttctgata aatcgagcat attgccttcc acaaattgga
    11581 tcgatgcgtc ttcttcatat gctcgctggc tggcaatcat caacatctct tctgaaaggt
    11641 ctaaccctgt cactttatat ccatcttttg caaaggcaac cgctaatgct ccagtaccgc
    11701 atgccagttc caaaatattt tttgtgtctt cttgtaaatg acgtttcgaa aaagctaacc
    11761 attgctgata aagtgtttcg tccatcactt catcgtaaat gaaagcaaat gtttcataag
    11821 ccatatgtta atccaaccat tcactaagat cgactagcgg agcatctgac catagttttt
    11881 ccagattata gaaatttcgt tctggcgcat ggaaaacatg tacgatcaca tctccaagat
    11941 cgatcaatac ccattttccg ccttcttttc cttcaatacg ttttacttca tatttgtttt
    12001 cttcttcttt atcaatgatt tcttctgtaa ttgcgttgat ttgacgttcg ctatttgctg
    12061 aacagatcat gaaataatct gccaacaagg aaacatttcg aacgtctaaa gcgataatgt
    12121 cttctgcccg ttttgaatct gctgcttcaa tcgcaatttt taattgttct ttactatcta
    12181 tgatgatttc ctcctaatat gagcagctta tttttttgct acccagtaat tatatgtttc
    12241 gattgttttt ggataaatct gttgttcttg cgcaagcaaa tgggccaatg tatgttttgt
    12301 ttcaaatgct acagcttcgt ctagatcagc ccatgcaatg gctcgtgcat cttgtacccc
    12361 aggaaaatct cgacctggtt caatatagtc tgctacataa atgattttgt caaggagact
    12421 catcttagca gccccagtcg tatgcacccg gattgcatga agaatctctg catcggtgat
    12481 tcctaattcc cgctctacaa acgaagcgcc aacaagacca tgccagattg cattattata
    12541 attcaataac tccggatcaa aaccgtctct tacgattacc attttgaact cctcatctgg
    12601 tcgttctttt gcataatcat gtgtcaatgc agcaatacta gctttttcag gagaagcacc
    12661 gtattttttg gcaagagcca cggctgtttc ttctactcca agcacatgct tgaagcgttg
    12721 ttcgctcatt ctcatctgta ttttttgcat caggttttct ctagaataag cagtatattc
    12781 attactatag tccatattca tacaaccctt cattttgaat ataatcaatt actttatctg
    12841 gaacaaggta gcggatagaa cagccttctt tgatcttttg acgtattttc gtggaactga
    12901 tgtcgatctc aggtacatct acccaaatta caggatatgg agtatccgtt gtgtatcctg
    12961 gtcgacgtat acccacaaag ttgaccatag aagtcagctc atcgatttta taccattttg
    13021 gcaaatattc taccatatcc ccaccgataa taaagtaata atctgtatcc ggattgtttt
    13081 gcgtcaattc cttcatagta tcataggtgt aacttttccc accacgagct aattcaatcg
    13141 tttcaatctg caaaaaagga ttgtcttcca ccgctaattc caacatgttg agtcgatgtt
    13201 ttgcatcaat cgtctgtttc tcatcaacat gaggtggctg ataagaaggc atcaaaaata
    13261 cgcggtcaag acctaaattc cggccagctt gttcagccat cactaaatgt gcaaggtgaa
    13321 cgggattgaa tgttccgccc aagatcccta cttgcttttt cttctctaag aattgaggca
    13381 tttcttcagg aaataattgt gaacgaacaa atgtcttagc ttgcgtattc atcatggtca
    13441 ctccttatat tgcttttact tcttttgata gcctttgata cttttctttt gtggaaggtt
    13501 tgtataatac aataacacgt ccaatgattt ggacgatttc gcaatctatt tctttttcta
    13561 atacttgagc tgcttcttct gcaatctcat ctgtattttg aagtaacgat actttgatca
    13621 gttctctttt ttctaaagct tcttcaattt gaacgatcat tgctgaattg atcccacctt
    13681 ttccgatttg aaaaatcggc tgaagatgat gcgctttgct acgtaaaaaa cgcttttgtt
    13741 ttcctcttaa actcataatt ttccttcttc cttaaatcaa tgctttgcgt ttcaatacat
    13801 ctacaccctt tggcgcccag cccgcaatta ctactggcgc tgttacagtg atccagccta
    13861 gaccggcaaa aacgatgtct gttttttctt tcacagaaaa ctcaaaacga acaagctccg
    13921 gaaatgcctc gacttcatca ggacgaggag gctgtaataa tccacctaca tgtttttgat
    13981 aaaattcgtc tgctttttcc agtttcgttc gatgaatatt tacatcattt gacacataag
    14041 caataaatga agcacgattg ccgctgataa aatcaaatct tgcaagtccg cccaagaaaa
    14101 gtgtttgccc ttcattcagc tgataaactt taggtttgat ttcttttaac ggtgcaatga
    14161 tccgcaaatc ttttttacct aagtagtgcg ccatttgatg gcgatggata attcccggtg
    14221 tatcaatcaa aaaatgcccg tcatctaaag gaatctcgat tttatccaag gtcgttcctg
    14281 gaaactgcga agttgtgatt acatcttgta ctcccgctgt atttttgatg atttgattga
    14341 taagcgtcga ttttccgaca tttgttactc cgacgatata gacatcccgt ccatcgcggt
    14401 attcttcgat tttttctaat agttccgtca tctcatgaga tttcttagca ctagttaata
    14461 atacatctac tggacgaatt cctgcttcgt aagcacgttc cttcatccat tgtgttaatt
    14521 tagttttttt caatgattta ggtaatatat ccactttgtt cccaactaaa agtactggat
    14581 tgtcaccgac aaaacggtgt agtcctggga ttagtgaacc attgaagtca aaaatatcca
    14641 ccacattgac gatcaatgca tctttttgcc ctaattcatt cagtaagcgc aaaaagtcgt
    14701 catccgtcaa tgagacatct tgggtctcat tataatggcg taatctgaaa caacgctgac
    14761 aatagacttc cccggaagct aaaccttttt ccaaagccgt ttgcggcgtg tatcctaatt
    14821 caccgggttt gtttgtttgt ataacggcac cacagccgat acattgtaat tcttctgtca
    14881 ttcgattcca cctcgccagc ccatatcagg gtgttttgct aatagatagg ccataattct
    14941 tttttcccaa aaacgattaa attgtgtctt ccaactatct gttgcgataa tgggttttac
    15001 aaggatgcta cgtatccctg cacgattggc tccacgtata tcagtcataa tctgatcgcc
    15061 taccattact atctcatcat ctgctaaatc caattgtttc tttgctatgt tgatccctct
    15121 tgctaaaggt ttcattgctc gtgcaacata caaaagatca aatttttcaa tcgctcgcgc
    15181 gacacgtttt gaattattgt ttgaaacaac aacaacaggg attcctgcat ttttcatttc
    15241 taaaatccaa gtaagcaact cttctgttcc atctggatta ttccatgcaa tcaacgtatt
    15301 gtctaaatcg gtcaatactg ctttgatgcc tagattcttt aattgggcag gtgtaatctg
    15361 atagatggct tctaccatcc atgttggttt gtaatttgaa aacatgctgt ctcctcatct
    15421 gcaaaaaatg aaggagcaca taaagtactc ctcaaccccg tattatactg catatcagca
    15481 aaaaaaacta cctctatact cgttcgtctt tcagaaaaag catttcttta caaaatgacc
    15541 aaaaataaag attgatcaca gaaaaattta gaaacaaaaa acaactaata ttggcggaac
    15601 ctcttgtatc gtttttccag taatttatgc tgatctaatc gaacaagttc cgtcaatctt
    15661 tcaatcaacg cttttttcat aatgtgtgcg actttatatc gtggcaactg ctcgccgttg
    15721 aacgtttcag gaataactcg atcaacgatt cctaactcgc gtagttctgg cgcagtaatt
    15781 ttcatcaact cagctgcttc tgcggcgcga ctaccgtctt tccacaaaat cgacgcaaat
    15841 ccttctggag aaagcacagc ataaatcgtt tcttccagca tccagacttc atccgctaaa
    15901 cctagagcaa gggcaccgcc acttccacct tcaccaatga tgatggcgat gatcggtacc
    15961 tttaaatcag acatttcgag cagatttctg gcaatagcct ctccttcgcc gcgctcttct
    16021 gctcctacac cgcaatatgc acctgctgta ttgatcaagg taatcaccgg tctattgaac
    16081 ttttccgctt gtttcatcag tcgtaaagct tttcgatagc cttcaggatg gggagaacca
    16141 aaatttctgc ggatattttc ctgcagatcc cgtccttttt gaataccgat cactgttacc
    16201 ggtttgccat ctaatcgagc gattccacca acaatcgctt cgtcatctgc aaataaacga
    16261 tcaccatggc attcctcgaa agaatcgaag atctcttcaa aaaaatccaa gcttgtccat
    16321 cgttctttag ctcttgctaa ctgaacgaca tcatgtgctg tcttatccac gatctatcca
    16381 tcctttctgt gtatgcaatt caagaagcgt atggattttc tgtttcaatt ccatgcgggg
    16441 aacaatctga tcgacaaaac catgagataa taagaattca gccttttgga aatcttctgg
    16501 aagttcctgc ttgatcgtct gttcgatgac gcgtcttcca gcaaaaccga tcaagctttg
    16561 gggttctgct agaataatat cgccttccat tgcaaaactg gcagttactc ctccggtcgt
    16621 cgggtccgtt aaaacagtta gataaaaaag accttcattg ctatgccgtt tgacagcagc
    16681 agagattttt gccatctgca ttagagaaaa gattccttct tgcatccgtg cgccacctga
    16741 agctgtgaac aagacgactg gaagactttc ctttgttgct cgttcgaata atctggtgat
    16801 cttttctccg acaatcgttc ccatacttcc catgataaaa ttaggatcca tcactccaat
    16861 aatgaaggga atcccctgaa tggttgcttt accagtgagg actgcttcat gaagtcctgt
    16921 tttatcttgc atttttttaa ttttttccgt atattcggga aatgctagcg gatctttggt
    16981 tacaagatcc gtatcccatt cttcaaaact tttttcatca ataatcaaag ctagacgctg
    17041 ccatgcaccg attcgaaaag cgtatccgca atgagggcat actttttctt caccgatgtc
    17101 tttcgtataa aggatatgtt tgcaatttgg acactttgcc cacatgttat caggaacaga
    17161 tggcgagtta gcaggtttgc tctctctatt aggattgatc cgaatatatt tctttttctt
    17221 aaacagagcc atctatgcgc ctcctatctc cgtttctggt gtccaattcg gtaaaaattc
    17281 ttcttgtaaa aatgctgtgc tgtaatcacc tgctatgact gcaggatgac taatcaaatc
    17341 catctgaaat tctgcgttcg tgatgattcc ttctgtgata aattcactta aggctcgctg
    17401 catcttcatt aatgcttcaa aacgcgtatt tccatggacg attatttttg caatcattga
    17461 atcataatat ggcgggatcg tatatcccgg gtaaactgca ctgtctactc gcagtcccat
    17521 cccacctgct ggaagcagta agttttggat cttccctgga gaaggagcaa aatggaaagc
    17581 aggattttct gcattaatcc ggcattcgat tgcgtgtcct tggaatacta cttcttcttg
    17641 acacacattc aaaggctcac cggctgctat ctccacctgt ttttttacta aatcgattcc
    17701 tgtgaccatt tctgttactg gatgttccac ttggattcga gtattcattt ccatgaaata
    17761 aaaatcgcct tcttcatcca tcagaaactc gatcgttccg gcattttcat aattgactgc
    17821 tttagctgct cgaacagcag cgtctcctag tgcttctctt tttgtttgtg agatcactac
    17881 agaaggagat tcttccagta ctttttgatt gttgcgttgt aaagaacaat ctcgctcgcc
    17941 taaatgaatg acatgaccaa atcgatcacc taagatctga acttctatat ggcgagcagg
    18001 ataaatgatt ttttccaaat acatatcatc atttccaaat gccgctgctg cttcttgctg
    18061 agctgaagaa aaatgctgtg ggagctcttc ttttgattga actttccgaa tgcctttccc
    18121 gccaccacct gcagctgctt tcagcatcac tggataacca attctgtctg ctatttccaa
    18181 tgcttcttct actgtagata atacaccagt acttcctgga atgactggga catttgcttc
    18241 ttgcatcaat tgacgcgcat tgatcttatt tcccattgca tcgatcgttg cacttttagg
    18301 accaataaat gtgatattgc actcttcaca catggaggca aatcggctat tttcagataa
    18361 aaaaccaaat cctggatgaa ttgcttcggc ttttgtcacg attgcagcgc tcagtacttc
    18421 ctgaacattc agatatgaat caacggcttt tgccgggcca atgcagattg cttcatctgc
    18481 taactgtgta tgaagtgctt cggcatctgc ttctgaatat atcgctacgg tttggatccc
    18541 tagttcgcgg catgcacgaa tgatacgtac agcgatttca ccgcggttag ctatcaatac
    18601 tttagaaaac atatttcacc tatccaatca taaaggttaa ttccgcttcg gctacttttt
    18661 taccgtctac tttagcgatt cctttgccta ttccggctga agctttcact ttcaatatct
    18721 caacttcaag gtataaggta tctcccggtg taactttctt acggaatttt gctttgtcca
    18781 atccgccgaa ataagccgtc tttcccttga attgttcaag agaaagtaat gcaactgctc
    18841 ctgcttgagc cattgcttca acaatcaata cccctggcat aacaggttct tctggaaaat
    18901 gtccttgaaa aaagggctca ttgatcgtta catttttctt agcaacgatc cgttctcctt
    18961 caaccatttc ttccactcga tcaatcaaaa gcattggata acgatgtgga atgatttctt
    19021 ttatttcttg tatgttcatt gttttccctc tttcctgctt tgcttatttt tgctgaatcc
    19081 taaagagtgg ctgtccatat tcgacaactg actcgttttc tacaaggatt tctgtgatca
    19141 ctccgtcggc ctcactagtt atctcattca tcagtttcat cgcttcaata atgcagataa
    19201 cttctccttt ggcaacttga tcacctactt ttttgaaagc tggtttgtcg ggcgctggtt
    19261 gcagataaac gattcccacg attggcgaaa caacctcgat tccatcaaat actgccgatt
    19321 ctttttcttt cattatttct ggagcagttg ttgcttgttc aggtatgaca ttgactggct
    19381 ccgaaactgg caacgtttcg tttgtttgaa ccatattcat gcctcgactt gttttatttt
    19441 tattcatata caattcaaat tgaccttcac gcaaatcgaa ttccgttagc gaggattgat
    19501 caaattgact gactaattct ctgatttcat tgatatccaa aattattcct cccagcgttt
    19561 catgcacaga accgcattat gtccgccaaa ccctaatgaa ttactcattg cataagtaaa
    19621 acttgcaggt ttgctttcgt ttttgacaac tgtcaagtca atctcaggat cttgtttttc
    19681 tacattgatc gtaggtggga taaattgatg ttctaatgcc agcaaagttg ccaaggcttc
    19741 gatcccgccg gctgctccca ataaatgtcc agtcatcgat ttcgtgctgc tgacgtaagt
    19801 atctctgaaa ttttcaccta atgcgatttg gattgctttt gcttctgcct ggtcattggc
    19861 tggtgtactt gttccgtgag cattgatata tccgacttgt tccggctgta caccagcttc
    19921 ttccatcgca agcttcattg ctttagatgc accagaacca tctggagtag gagctgtcat
    19981 atggtaagcg tcacagtttg caccgtatcc aacgatttct ccatagattt tggcaccgcg
    20041 agcttgtgca tgttctaaag attcaagaac tagaacgcct gctccttcac ccatcacaaa
    20101 accattccga ttttcgtcaa acggaatcga accacgatta ggatcagttg attctgagag
    20161 tgctgttaaa gctgcaaatc cagcaatccc catctcacaa atcgttgctt ctgttcctcc
    20221 agcaagaatg acatcagaat agccatgttt gatgttacgg aatgcttccc caattgaatt
    20281 cgttccgcta gcacaagctg ttacgatagc tgtacaaata ccttttgcac ctacacgcaa
    20341 agcaatattt ccagctgcca tgttggcaat cgccattggt acgaacattg gagaaactcg
    20401 ttttgcacct ttttcatgta gacgaataac ttggttttcg attgttggaa gaccaccgat
    20461 cccagatccg atgatgacgc caaaccggtc ttgattcatt ttttctttat ctaaaccgct
    20521 catctccatt gcttctaaag cagcgtagat tccatagatc gaaaacatat ccattcgttt
    20581 gctatctttt ttaataaaat atttatcgta agggaaatct ttgacttcac ccgctaaggt
    20641 aatccctgtt tctgaagcat caaatttagt gatcggtgcg atgccattcg tcccctcttt
    20701 taagctattc aaaaagctgt ctgcgtcatt tccaataggt gaagtgactc catagccagt
    20761 aattaccact cgattcattt gtttgctctc cttttcttat ccgtgcatga ccaatccgcc
    20821 atcgacattg atgacttgtc cggtgatata tggattttgt gctaagaaaa ctgctgtttg
    20881 tgcaatatct tctacttgtc cgaaacgctg catcggaatt tgcttttccg cttgttcctt
    20941 gactttgtct gctaaaactt ccgtcatatc agttgtgatg aatcctggcg caatggcatt
    21001 acatgtaatg cctctagttg cagcttctcg tgccacagat tttgttaatc ctactacgcc
    21061 agctttacta gctgcataat ttgcttgacc aatatttcca atcaacccag atacactaga
    21121 gagattaatg atggcccctt ctcgctgctt catcattttt ttcaatacgt gctgcgtcat
    21181 attgaaggtt ccaatcaaat tgatatccag acattttttg aaatcttctg catccattcg
    21241 catcacaagt ttgtcatttg tgattccggc attgtttact aacacatgga tcgatccaag
    21301 cttttcttct gcttctttga tcatttgtcc cgctttctca taatcagaga tgtcaccgga
    21361 aactcctacg cattttacac cgaatgcttc gatttcttct atcttttctt ttggaatctc
    21421 tccgcgacca ttcaaaatga tatttgctcc agcttttgca aaagctaagg ccatcgcttt
    21481 gccgattcct cttgtactac ctgtgataaa tacatttttt ccttttacat ccataacgtt
    21541 cctccttata gtattgctat tgtttcatca aatgtctgct tattctcaac acgcagaact
    21601 ggtattgttt tatcgatttt tttcataaat ccgcttaata cttttccggg gccgacttcg
    21661 atgacttgtt cgatgccgat tgtttttaac ttatggatac tctcatagaa acgaacaggt
    21721 tgcatgactt gctgttcaag tagtcccgcg attgtttctt tcttcattat ttccgttgtt
    21781 gtgttgctta tgataggaaa agaaggttca gagaattgaa tctgacttag gtccttcgcc
    21841 agtttttttg ctgccggttc taaaatagct gtatgaaaag gcccgctgac atttagaggg
    21901 atcattcttt tgaacccttt ttcttttaat agtaaaacag cttcgtctac tgctttttct
    21961 tcgccaccaa tcacgatctg ctgaggtgta ttataatttg caggagatac gatgccgtac
    22021 ttgctagctt catgacagct ttcctcgatc gtttcaatcg gcgcattcat cactgcaacc
    22081 attttcccgc ttccagctgg ggcagcttct gtcatataag cgcctctttt tgctactaac
    22141 gcaactgctt cagtgaagga tagcgcatta ctagctacta atgccgaata ttctcctaaa
    22201 ctcagtccta aagctgcatc tgggatgatt ccatgctcct tcaataagcg ataatacgcg
    22261 atgctgactg ttagaatagc tggctgtgta tattgcgtct gatccaaacg ttcattttct
    22321 gtaaagcaaa gttcagccat atcgtagccg agaatctcac ttgcttcatc aaatgtctgc
    22381 tttacaacgg cttcttcata taaatctttt cccatacctt gatattgtgc accttggcca
    22441 ctaaataaga atgctgtttt catgtttttc tccaatatat ccagaatata tgtttgattc
    22501 ttcctattca aaaaggccga gacattccta tttcaggaaa tgtcccagcc cccaacctaa
    22561 ttttaatgat tatgcagttt gtttttctac gtaagtcact aaatcttgaa ccgttttgat
    22621 tccgtcttct gtttcgattt tcacgtcaaa ttcatcttca atttcattga tgatttggaa
    22681 taaatccaag ctgtcagctt ctaagtcttc ttggatgtca gtagtcaatt tgatttcttc
    22741 agtttctttt cctaattctt ctgcgatgat ttcttgaatt ttttcgaata ccataataat
    22801 atattcctcc gatattgttt gctttttatt tttataattt aacagtctac aactccatga
    22861 gaatacttcc ccatgttaaa cctccgccat agcctgtaaa tattactttc tgctgttttc
    22921 ctaaggtgat ctttccacta gaaactgctt catccaataa gatagggatg cttgcagcag
    22981 atgtattccc atatttatcc atattggtca ggaacttttc ttgcggcatc tttacttttc
    23041 gggcaatttt ctcaataatt ctgaggtttg cctgatgcaa aagcagataa tcaactggtt
    23101 tgtctttcat gacttcttgg atattgtttg caacgtctcg tacggcaaaa tcaaaaatat
    23161 ctctgccagt catttgcaaa taatacgaac cttctgaatc ttctgaatag aacggatttt
    23221 tattttgctg gtagccagcg gtcaatgagc tacttctggt accgtcagct gctaattttt
    23281 ctttcagcaa ttttttctgt ggattcgctt ctaagagaat cccacctgct ccatcgccaa
    23341 acaacacagc agtcgtacga tcagaccaat cgattagctt agatagtgtt tcaccaccaa
    23401 tcaccagtcc cttagttgag ccgcagcgga tcattttttc agccatgctt aacgcataaa
    23461 caaatcctga gcacgcagca ctgatatcaa aagcgatagc atgagttgct cccaatttcc
    23521 cttgtacttg tgctgctaca gatggtgtcg tgtaatcggg cgacattgtt gctactaaaa
    23581 taaaatccaa atctttaggg tttagatttt tctgttttat caatttttcc gccactaaaa
    23641 tgcataaatc agaagtctcc tgatttgtta cacatcttcg ttcacgaata cccgtccttg
    23701 acgaaatcca ttcatcagag gtatccatca tcttggaaag atcattatta gtaataatct
    23761 tttcaggaag gacgctggct gttgcagtaa tcattccaaa ttgttccatt aaatatcctc
    23821 acttatagtc ttgcaagaag tcgtgcaagt ttttcagtgc atccagcaag gcatgctgtt
    23881 cctccgtagc cattccgtct aagatgttct tgaccatttc acgatgaaaa tgctgatgga
    23941 cccgaaatag taactttcct tttttcgtta gtcccaactt tacaacgcgg cggtcatctt
    24001 cactgcggat acgttcgaca tagccttttt ttactaactt gttaatagca gtggtcaagg
    24061 tcccaacagt aattgatagt tctttggcta cttctgaagt tgtttttttc ttgtacatcc
    24121 cgattgcctc gatcgtgtgc atctctgtga ttgacagatc tttgaattga gattttttca
    24181 gctcagactc ttcgattgtc aaaatatcat tgaagacact aacaagataa tcatttactg
    24241 tttttaaatc tggttccatg ttccaccgtc cactaattag tttgattatc aaatcttttg
    24301 atgttcaaac tatatcttaa cttttttcaa aatgcaacct taaaagatca tttttttact
    24361 atatgagctt tttttaagat tttactcatt taaaacaact gataaatcag catttataat
    24421 ttcttttatt agaaaaatca tctatctcac atattttgat tatcaaagta ttttctgtga
    24481 acagaactat agaattccct aaaacttgtc cattatttca aaatttgtta tagtcttttt
    24541 attcaaagcg taaaaggaga tcctatgtta aaagaaaaaa tgaaaactct ccccatgctg
    24601 ccgggtgtct atcttatgaa agaccgagat ggtaaggtca tctatgttgg taaagcaaaa
    24661 cggctcaaaa atagagtaag cagctatttt catcagaata aacagcattc aaaaaaagta
    24721 ttacgtatga ttcatcatat aacagatttt gatttcgtcg tagtagacac ggaattagat
    24781 gctttattgc tcgagtgtca attgatccaa cattaccgtc ctttttataa ccgacaaatg
    24841 aattatttca gtaattataa ttatgtacat attaccaata agggatttgt attaacagat
    24901 actcctacgg ctcgaacata cgggcctttt cgtctctata aaaaaatgcc gtctattttg
    24961 cgtataatgg aagaaactta tcaaatgcct tggttgtctg aaattagttt gttagctttg
    25021 cgagtccagc ttcctgacct acaggaaatg acttttgaac agaaaaaaaa ggaactccaa
    25081 gggctgtttc aaggccgaaa taaaaagcta ctgacttact tgaaaaaaag acaacaacat
    25141 ttcatctatc agttgaattt cgaaaaagcc ggtatgcttc aaaaagatat cgaattagtt
    25201 acttatttta ttagacggat ccaggaacaa aagcagtttt taagaacacc atcgctcacc
    25261 ttcagcatgc cattagcagc agatgagagt cagaaaaagc actacctcgt ttgttatggt
    25321 caacttgcag aaacaatgat tacctctggt gacgtttctc ctgacttcta ttatgaaaag
    25381 aaagaagctc atttatcttt gaaacgtcaa ttgtcaaaag aagaaatcga tcctgtacaa
    25441 atcttgatca gttaccgcaa aaaattagaa aaagaacagt ttgaaattga actgttaaac
    25501 aaaaaagaag ctgaaaagca actaaattag ttgcttctcg gcttctttta ggcatcttca
    25561 acttcaaatg tcaattatcc taaaatttat tggattaagt catagatttc catcgctacg
    25621 atatcgatat tatcaaattc gtattgctga tgagtatctg tttcagttaa ttcaaatgta
    25681 tcggtcgctt tatcataagt tactgtacac ttctctacgc cttctttttc aaaacggcga
    25741 acttgcagtt cattatctgc tgactcgacc atagcctcca gtcgttttat gattgcgact
    25801 aattgtgaat gtgtcatcgg aggtcctcct tttcttattt ctgttatatt gtatcaaaag
    25861 catagcctac ttgcattgat tttctctaaa aaaactcgtt ttttatgatt ttttttctgg
    25921 tatttttcct tcaggccacc aaagtttgat caaagcttgg gttccgtcat tctcaaaacc
    25981 tttatctgcc aactcttcat atagtttcaa tgcttgggta gttgctggca atacaagatc
    26041 cattttttct gcttcttcta atgcaatctt taaatctttg ataaaatgtt tgacaaaaaa
    26101 accaggtgtg taatcttctt ttaaaatacg aggagaataa ttgcttaaag accagttagc
    26161 tgcacttcca cctgaaagcg tctcaatcac tttctttaaa tcaagtccgt ttttttgtgc
    26221 atagacaagc atttccgtca ttcctgtcat cgtacctgca atcatgatct gattagccat
    26281 ttttgtatgc tgacctttcc cagcagaacc atgcaatgta aatgtcgtac caaattcttt
    26341 gaataaaggc agtacttgat cataaacggc ttcttctcca ccgaccatga tcgtcagtgt
    26401 accattcttt gctcctaagt caccaccgga taccggtgca tctaacgcat ctgcgccttt
    26461 ttcttttgct gtttttgcaa ttttttctgc caggcttggt gtacttgtag tcaaatcaac
    26521 taaaatatgt cctgagatat ctgcagaaaa aatccccgac tgtccatagt agatttcttc
    26581 tacatctttg gggtaaccta ccattgtaaa gagaatatta ctttgttctg ctaccgcttt
    26641 tggtgtatct gcccagatag ctccttctgt tactaaagga tcagcttttg cttttgtccg
    26701 attatagaca gctacttcgt gtcctgcttc tagtagatgg cgtgcgacag cacttcccat
    26761 gacgcctgtt ccgataaaac caagtttcat tttttcgacc tcctaaaaat caaaaatcct
    26821 tgcttctatg ctagtatacg ctagaaacaa ggattttttc ataaaaaatg tttgaatttt
    26881 atcttttaaa tgaatttaat tttattttga ttcgttcaat cgagtcttct tcttcttttc
    26941 ttcgcatctc ttcttcatga taaacaacca tgtcttgata aaattcgatc atagcttcgc
    27001 cgaaatgtgt agatgaaata tcataaagtt tagcttctaa aacttttgga tctttaggaa
    27061 cttcactgga aatataatca ataagtgctg gtgcaaagtc ttcgtcggtt tcaaaagttt
    27121 tccctaatga aggatgatcg aacaatcggt tcaaataagc atttccttcc acgacacaag
    27181 gtgttccggc tgccatcgct tctgtataag taagcccttg tgtttctgaa gtagaagcac
    27241 tgacaaaata atctgccgct ttataataaa gtgctacatc attgttgtcc acttctcctg
    27301 tgaactgcac aaattcttct aactgcagtt ctgagatcaa ttcctctaac tcttctacat
    27361 aaggtccttt tcctacgata actaatctgg cgttaggata agcggagatg acctgaggaa
    27421 acccattaat caaggcttgg atatttttct cataagaaat cctgcttaaa gaaagaatca
    27481 tcaaatggtt ttcctgaaga cctagtgact cccttaattt gctgatatcc tgctgagtga
    27541 tatcagaacg tttgaatttt tcaatgtcga taccagtagg aatcacgcga agcggtgcta
    27601 ttacaccata gctgcgtaat gtatcaataa cacgttcact tggacaaact acacctgtcg
    27661 tatgatttgc aaataatcta gacaagtatt ttacatggga ttgcctgatc acttttcctt
    27721 taccgatata atgaaggtag tcttcataca tcgtatggta agtatggatc agaggtattt
    27781 tcaacttctt agctaccatc ttcccaagta tccctgctcc gaattctgta tgggtatgaa
    27841 taagatctag ttctagttct ttggcaacca aataagcata ccacatgcct ctaacaacaa
    27901 ctcttcgatc cttgaaagaa ataaatggta cacttggcat tcgaatcaca tctttttcca
    27961 acttatccgc attaggatcg gtcgttgtaa aaatatagac ttcatgccca tgtctttcta
    28021 attcttgttt taatgttttg atcgatgtag caactccgct gacttgcgga aagtaggtat
    28081 cggtaaaaaa gccgattttc atgtttttcg cctccaaact agtccttgac ctgatttact
    28141 ttttttaatt tgctagagac tttttcattc agtacacttt cgtatacatt tttaagttct
    28201 tcaccgattt tattgatact tcgctctttt gctgtttgat aaccggcttg tgtcgtactc
    28261 ggtagttctt gattggtaat ctgttggatc agtcggataa attcttcgtt tgtcttcccc
    28321 atatagcagt tcttgctatc ttctaaccag ccattataca ctggaatatc tcgaacaagt
    28381 acgttttgtt tgcttgctaa agcttctaaa acaacgatcc cttctgtctc ttcataagaa
    28441 gggaaaaaga atagatctgc acctgaatac gcaccttcta tgatctctcc acgaatgtaa
    28501 ccaggaaaca ggacattttc aggatgatct tcttttacaa ttttccggat gttccgagga
    28561 atcgagtaca tgggaacatg accaaaccaa ataaatgtgt attcgggcat cttcttagca
    28621 atttctacga aatcaatgat tcctttacgt tcgaaaaaca aaccgacaca aatgattact
    28681 ttttgatccg gagacagttt gaaatattct ctgaactttt gttctttcat tggatcaggg
    28741 tgatatttct ctaagtcgat cccattggaa atagcttgaa tcggcacacg gataccatag
    28801 ctttccaaca actgttttga ataaggtgtt ggcgtgatca gatagtccgc tttttggtac
    28861 aatcctacca gatatttttt tacgatagga gaaagctggt tcgatctgat aaaggaattt
    28921 cggaaatctt cctctgtaga atgcgcatga tagacaactt tttttccttc tcttctggct
    28981 ttattgacca tattatgact attgattccg tatgtattga tgtgcaggat gtcataatct
    29041 tctttttcat ctagtgtata agagataccg acttccgtca gagcacgttt ttgatgatca
    29101 agcgcacgcc cgattccaga ttttgcaagc atcttttcac tttcaaaata taataatacc
    29161 ttcaccttac gtcccccttc acttatatag tataacatag cctacaaact gtcactcaaa
    29221 cttaagccct atttttgtct attcttactg acaaaaacgt tttcttaaaa aagaacaaaa
    29281 aaactggcgt agctctttta caagccacac cagcttttga tacgttgttt attttacata
    29341 ttcatgaaca agttcaacga cttcttccat catatcgcat tctttcaatg cacgatcagc
    29401 aagttcagcc attttcgctg tgtccaagcg tttcattaaa ctacgcgttt taagaataga
    29461 tgtcgcactc attgagaact catctagacc catacctact agcaatggaa cagctgtttg
    29521 atctccagcc atttctccac acatacctgc ccattttcct tcagcgtgtg ctgcatcaat
    29581 tacatttttg atcaaacgta aaattgatgg gttatatggt tggtacaagt aagaaacgcg
    29641 ttcgttcata cggtctgctg ccattgtgta ttgaatcaaa tcgttcgtac ctacagagaa
    29701 gaaatctact tcttttgcaa acttgtctgc taagactgct gctgctggaa tctcgatcat
    29761 gatgccgact tggatcgtat cagatacttc cttgccttca cttatcaatt tttgtttttc
    29821 ttcttcaaag atcgcttttg ctgcgcggaa ttctttgagt gtagctacca tagggaacat
    29881 gatacgtaaa ttaccatgaa cagatgcacg aagcaatgca cgcatttgtg tacggaacat
    29941 ttcgtcgcct tgttcagata aactgatacg caatgcacga tatcctaaga atggattcat
    30001 ttcatgaggt aattgcagat atggtagttc tttatctcca ccgatgtcca ttgtacgaac
    30061 aactacaggt tttccttcca taccttctaa tacagctttg taagcttcat attggtcatc
    30121 ttctgttggg aagtctggag aatccatata caggaattca gtacggtaca gaccaactgc
    30181 ttctccacca ttattatgga caccaactag atcttttggt gttccgatgt ttgcagctaa
    30241 ttcaaaatgc ttgccgtcag ctgtgacagt ttctgcattt tttaattttt cccattctgc
    30301 tttttgtgct gcgtaatctg cacctgcttt ttcaaattca gctttttgtt catctgtagg
    30361 atcgatgatt acatcgcctt cgatcccgtt gacagccaaa atatcgcctt ctttgacttt
    30421 agcagtaatt tcttttgtcc caacgattgc tggaatttct aaagaacgtg ccatgatagc
    30481 agaatgtgaa gtacgtccac caatgtctgt tacaaacgct tttacaaaat tgcgatctaa
    30541 ttgtgctgta tcacttggag tcaagtcatg tgcaacaacg accacttctt cgttgatcat
    30601 tgatggattt ggtaaagtaa cgcctaataa gtgcgctaaa atacgtttag caacgtcacg
    30661 aatatctgca gcacgctctt gcatataagc attatcttcc attgcttcga acataccgat
    30721 atacatatcc gttacttctt ttagcgctga ttcagcattt acgctgttgt ctttaatatt
    30781 ttgcttgatt tgacctacca tttctggatc tgaaagaacc atcaaatggg catcaaatac
    30841 ttgcgcttct gcttcaccta agctttgcgc tgctttttca cgaatttgct gcaattcttc
    30901 agtagattta gctaatgcag catccaaacg agcttcttca gccgcagtat cttctactgt
    30961 tgccttactg aatgttaaat ccggttgaac tagcaggtaa gcttttgcaa cggctacacc
    31021 gtcactagcg gcaatccctt ttagcatttc aaccattatt cagataagcc ttctttcttc
    31081 attgtttcaa cgattgctgc cattgcatca gcttcgtcag caccttctgc agtaatagta
    31141 acatcagaac cttgacctac acctaaagac ataacgccca tgattgattt caagtttact
    31201 gatttacctt tatactctaa gtttacatca gagttaaatt tgcttgctgt ttgtactaat
    31261 agtgtagctg gacgagcgtg gatcccagtt tctgctacta cgtgaaattc tttcttttcc
    31321 atattaatcg gtctccttta agtgagtgtt gtttttatgt gagggttttc ttttttagta
    31381 attcagagaa tcctaacaaa tgccaccctt tcatctgtaa agattaacat tttttttcgt
    31441 tagatacaac agttttcatt caatttcaga taaaagtatt caaattattc cggattcttt
    31501 ttcatccttt tcttcacatt ttataacaaa cgtgtttatt tcctttttct tgtcgctttc
    31561 tcttctcctg acgtttatca ttctttcctt tgaccctctt tgttttcata tgaaacgaat
    31621 tacttgcttc cctttttatt tttagtataa taagagtcaa aggtcaggaa tggtcaatag
    31681 agatttcacc ttttctacct cataaatctc ttaaaaaact aggggttatt cttttacctc
    31741 atgaaaaacg agatgtaaaa tatggatgta cccatttttg tgaaaggacg tgaatgattc
    31801 atgctttgtc aaaactgcgg caagaatgag gcaacgattc acttgtatgc cactgtcaat
    31861 ggtcagcgga cacaactcga ttactgtcag agctgttatc aaaaaatcaa aaatcaacaa
    31921 aatggaggtc tgactaatat ggcccaaaat gatccatttg gatttggcag tttggacgat
    31981 cttttccgtt ccatgtctcg ccaaatgcaa cagcaaggaa attatgagca aacaccacca
    32041 acacaatttg gcggaaacaa caacttcaat ggtggtcagc cacctcaagg caatacagaa
    32101 ggtttattgg gagaatacgg aatcaatatc acagaacaag cacgacaagg tgatatcgat
    32161 cctgtgatcg gacgcgatga cgaaatcaaa cgagtcattg aaattttaaa tcgccgaacc
    32221 aagaacaatc ctgtcttgat tggagaacca ggtgttggta aaacagcagt tgttgaaggt
    32281 ttagcacaaa aaatcgtaga tggtgatgta ccgcaaaaat taatggacaa agaagtcatt
    32341 cgtttagatg tcgtatcttt agtccaaggt actggtatac gaggacaatt tgaagaacgt
    32401 atgcaaaaat tgattgaaga gatccgtcaa gcagaaaatg tgatcctatt catagatgaa
    32461 gttcacgaaa tcgtcggtgc tggttctgct ggtgatggaa atatggatgc tggtaatatt
    32521 ttaaaaccag ctttagctcg aggagaattg caaatggttg gtgctactac cttaaatgag
    32581 taccgcatca tcgaaaaaga cgctgcttta gaacgtcgta tgcaacctgt acgggtagat
    32641 gaaccaactg tcgaagaaac gatcagtatt ttgaaaggtt tgcaaaaacg ttatgaagac
    32701 tatcatcatg taaaatatac tgatgaggcc atcgaagcag ccgcaacttt atccaatcgt
    32761 tacgtccaag atcgcttctt gccggataaa gccatcgatt tgctagatga aacaggttct
    32821 aagaaaaact tgacgatcca aatcgttgat cctaaaacaa tcgagaaaaa actgcaagaa
    32881 gcagaagaac aaaaagtttt agcttctcga gaagaagatt tcgaaaaagc agcttattat
    32941 cgcgatcaga tcaataaact tcaaaaaatg aaagaacgtc agctcactga agaggaaaca
    33001 cctgtgatta ccgaaaaaga tatggaaaaa atcgttgaac aacggacagg tattccagtg
    33061 ggtgaattaa aagaaaaaga acagacacaa ctgaaaaact tagcagatga cttgaaagct
    33121 catgtcatcg gacaagataa cgctgtagat cgagtagcga aagcgattcg ccgaaaccgt
    33181 gttggattaa acaaacagaa tcgtccaatc ggctccttct tatttgttgg accaactggt
    33241 gtaggtaaaa cagagcttgc gaaacaactt gcctacgaac tattcggttc acaagattca
    33301 atgattcgtt tcgatatgtc tgaatatatg gaaaaacata gtgtctctaa attgattggt
    33361 tctcctccag gttatgtcgg atacgaagaa gctggtcaat taacagaaaa agtacggaga
    33421 aatccttaca gtcttgtctt gttagatgaa gtagaaaaag ctcatccaga tgttttgcat
    33481 atgttcttgc aaatcttaga tgatggtcga ttgacagatg cacaaggaag aacggtcagc
    33541 tttaaagata cgatcatcat tatgacaagt aatgccggaa ctggtaaagt agaagcaaac
    33601 gttggttttg gtgcggcacg cgaaggtgtt actcgttctg tattgaacca attaaacaac
    33661 tactttacac cagaatttct gaaccgtttt gacgggatca tcgaattcag tgcattatca
    33721 aaagaaaact tgatgacaat cgtcacacta atgctagacg atgtcaacca aatgctggca
    33781 gcacagcaac ttcacatcga agttcctacg aatgtcaaag aaaaattagt tgacttaggc
    33841 tatgatccat ctatgggtgc tcgtcctctt cgacgcacga tccaagaaca aatcgaagat
    33901 ggtatcgctg aattttatct tgatcaccct tctatccatg agttgaaagc aaaactggat
    33961 aaagatggaa aaatcatcgt tacttctaaa ccagaacgtt tggctaaaga atcagccgaa
    34021 gaaacggctg aataaatcca gttttatagc gtgagacggt atttctttga gaaatgccgt
    34081 ctcattcttt tttcagaaaa gtcaaaatac tgttcatttt ataaaaaaga aattataata
    34141 agagaaacaa gcaattaaaa atacataaaa gaggtgagcg ccatgaaatt ggtaaatgta
    34201 acaaacagcc attcccgtct tgtattaaac cagcttgaaa acactgatgc ccatctagtc
    34261 aaggtctaca cagccggaaa taccactatt gtctacactg aagcccctga acataatgaa
    34321 attctgctga tcaatgacaa acgtaaaatc cagccgaaag aaatcgaaga tgctaaaaat
    34381 tatttcttag ataaaatcaa agacgccgtt taccacgagg atgaaatcaa agtaatcgaa
    34441 ttggcaggcc ttgttgaaat ctcgattcca aaacatgaat taggcgctac attagccgtg
    34501 taaacaaatt ttgaacataa taattaaaga gcgtgggaca aaagtaaaga acacttttgt
    34561 ctcacgctct aaacacgtat aaacggcgaa agcagaagca actccttcgg aaataagctg
    34621 aaattcacga aaattgcttt tcaaattttt gtgaattcca gcttatttct tggagttaaa
    34681 cgcttctgtc tcagcctctt tttctttcta gctttttgat ttttctcttt tcttttgtac
    34741 ttttctcttt tcattttcag ttctacgcgt gtctttattt ttaacttttt cctctttatg
    34801 gatgattgat cgtacttttt gtgcaatttg ctcgtttttg tcccagtctt ttacatctaa
    34861 taatcgacat aatcgtaaca tctcttcttt tttctgtttt tttctttcac gtctttgcca
    34921 ttctgtttcc atgtgtcaca ctctcctttc tttaatcata tgtacgcaaa ataattttta
    34981 tatttttttg attagacatt tctatgattt taatatagta aaaagagccg tcacggaaaa
    35041 tccgtcacgg ctctaaacaa aatatgagag gctgtttttg tttggctatt cttattactt
    35101 gatgcagggc agcttgtgtc aagacttctt tacatcaaac tttttaattt tacattggga
    35161 tatttatccg caaaccagcg ttctgcaaat tggttctcga ataagaacaa cggttggtcg
    35221 aaacggtcac gagccaagat attgcgactt gaactcatct tctcatccaa atcttctgga
    35281 tcgatccagc gagcgatttt gtgtcccatt ggagacatga ttacttcggc gttatactca
    35341 tttaacatac gatattggaa tacttcgaat tgtagctgac caacagctcc aatgatatat
    35401 tcttccgtta gatatgtttt ataaagctga atcgctcctt cttgaactaa ttgatagatt
    35461 cctttgtgga aggatttttg tttcatgaca ttttttgcag tcactttcat aaacagctct
    35521 ggagtaaatg aagggagttc ttcataagca acttttagtt ttccttcgaa caatgtatcc
    35581 ccaatctgat aattgcctgt atcatataca ccgatgatat cgcctgctac tgctttttcg
    35641 acgttttctc tcgaatctgc cataaattgt gtgacattgc ttaatttcag ttttttattt
    35701 gtacgttcca accagacatc cattcctcgt tcgaatgttc cagaacagat tcggacaaaa
    35761 gcgattcggt cacgatgggc tggattcata tttgcttgga tcttgaatac gaaacctgaa
    35821 aattcttcct cataaggact taccatctga tcatcttgtg ttttgtgtcc ataaggagct
    35881 ggtgccaatt caacgaaagt ctctaaaaaa gtctgtacac cgaagttagt caatgcagaa
    35941 ccaaaaaata ctggtgtctg atcgccacga gcaatttttt cttgattaaa tgcatctcca
    36001 gcctctttga ttagttctac ttcttctaag acttgttcat ataaggaatt ttcagttaga
    36061 ggatgatttt cgggaagcag tccatcttca tccaattcta ctaatcgttc atcctgataa
    36121 ttttccggac gataaaactc tacacgatta tggtagatat cataaagacc ttctagccct
    36181 ttacccatac cgattggcca attcatcgga taagattcga tatctaatag ctcttctaat
    36241 tcttctaaca attccaatgg ttcacgacca tcacgatcta gtttgttgat aaaagtaaat
    36301 atcgggatgc cacgtttttt tacaacttgg aataatttct ttgtctgtgc ttcgatccct
    36361 tttgcactat cgattaccat gaccgcacta tccacggcca tcaaagtacg ataagtatct
    36421 tcagaaaaat cttcatgtcc tggtgtatcc aagatattta ctcgtttccc ttgataatca
    36481 aactgcataa cagaactagt aacagaaatc ccacgttgtt tctcgatttc catccagtct
    36541 gatttggcaa aattacctgt ttttttgcct tttacggtcc cggcttgacg gatagcccca
    36601 ccaaacaata gtaattgttc tgtaatcgtt gttttcccag catccggatg ggaaatgatc
    36661 gcaaaagttc tgcgattgtc cacttgttgc tttaattttg gattattcat aacctaactc
    36721 catttcttcc attcaattat ttatattttc tctaggcaca gattgtccga tctcttaaag
    36781 aaagacaatt tcatataggg ctgtgacaaa agccgtgtag cagtctcttt ttccgagtaa
    36841 acggcgttct agagacagcc tatcagcaat aagcccaccc aagccaaaaa tacgaaaagc
    36901 tgtttttgct tggctgctct tattacttaa tgcaggatag ctttttcaca acctttgtca
    36961 actactacaa ctgaatcagt atagcatgga ttcagcgaat gaaaaagcca ccaaaccata
    37021 agagtcaaat atttttttgt cagctgacta aaagaaaaga cgtgttgctt gtttattcaa
    37081 gcaacacgtc tttcataacc aagtttccaa ttatcttctt ggctcgtcat cttcgaattc
    37141 ttttctgaag tatcttcgtt cttcttcagg ttccgcttct gtttcttccg gatcatgaaa
    37201 aatgacacgg attttaagga ttcgagaacc ttccatttct tcagaaacca gcgtaatatt
    37261 atcgacatca aacgataact tttcgccttc atccggaatc atgcctaatg ctgtaatcaa
    37321 ataaccagcc atcgtatcta catcactcat atgcagatca ctgtcaaaag cttcattgaa
    37381 ctcatcaatc agcatacgtc cttggatgat atattcgtgt tcatcgattt tttcataaag
    37441 attctcaact tcatctgatt catcatcgat ttctccgacg atttcttcta aaaggtcttc
    37501 tagtgttgct aacccaacga cgccgccata ttcatctaat aaaatagcca tctgattctg
    37561 cgtctttttc atttcatata acagatcatc aataaagacc gtttcaggaa cgaataaagg
    37621 ctcctgcatg attttcttga tatctaaatt atcaaagccg aatttatggg cagcttttag
    37681 taaattcttt gtatgaagga ttccgactac tttatctttg tcttcgttat aaacagggat
    37741 tcttgaatag ttttcggata aaacttcatt cacattttct tccacagtgt cgttgatatc
    37801 aatcataaat gcatccgttc gtgggaccat gacttctcgg gcaactttcg tatcaagaga
    37861 aaaaacccct tggagcattt ctaattcttc attattcaat acgccttcgt tttcaagcat
    37921 ataacgcatt tcatctctgg tcatttttga atcttcatca tcaaaagtca tcggcgtgat
    37981 acgcgccaat aaacttgtgg aagcagaaag cagccagacg aagggcttag ctactacacc
    38041 aatcaagcgt atcagccctg aagtgaactt tgcgacttct tctgatttat ttaaagcaat
    38101 acgtttaggg tacaattctc caaaaacaat cgatacatag gtcaaaatag ccagcacaat
    38161 gatatttgca atattttttg ccgctgtgcc gccacctaat accggagcta accgttccga
    38221 taaagtatta gctagtgaag caccagacaa aatgttgacc aaagtgattc ctacttggat
    38281 tgtcgatagg aaattatttg gattctgcaa tatttttaaa agcttttgag atttcacatc
    38341 tccttcatca gctttttgct cgattcgatt cttattgatc gaaacaacag caatttcgga
    38401 agctgctaaa aaagcattga tcaatgtcaa aacgatcaat aataaaatct gcgctaacag
    38461 cgactgactc tcagggtcag cattcataat cgcattctct ccttataaaa ttaattttta
    38521 gtttacgata gaaaaaaacg tggcactata gccacgttaa aatggtatca caaagcaatt
    38581 ttctttgcaa taaaaacaag tgtactaaaa ctacctacga ggtcgtagca attttcttct
    38641 tgttttcatt ttgcttgtct tctttgacga ttttgattat ataggaaatg atcgtcttgc
    38701 agattgcgta aaaaggaaca cctaagaaga taccaagcaa tccggcaata tttccagcta
    38761 ctagaagaac gataatgatc gttaatggat ggattttcag tgatttccca attacattag
    38821 gataaatgat attcccatcc aactgttgga cgattagcac aaccacacaa caaagtaatg
    38881 cttttaccgg atcattgaag actgttacta gaaatgcagg tgctagtcct agataaggtc
    38941 ctaaatatgg aattaggttt gtcaatcccg caatgacccc aaataagaaa gcataatcca
    39001 caccaattac catatatcct aaaaatgtga aggtaccaac gaataaacat tcgattgctt
    39061 gtccgctaat gtaattagcc aatgttttat tcagttgccc caataactcc acaatttggt
    39121 ttcttctttt ttctgggaaa aactgttgga tgtttggcac tagtttttct ccgtctttca
    39181 acatatagaa caagatgaat ggtgctgtaa tgattactac ggttgccgaa gcgatcgttc
    39241 caacgatcga acctaaacta ttggatactc cactaaggaa ttgctgaatg attgtcccgt
    39301 aagaaatgtc taattgctca aaatatttat tgatatctac ttccttgaac aaaggcaatt
    39361 cggctacctc ttttaaccag ctttctacct gtttgatgaa atcaggcata ttagatgcca
    39421 atgaggaaat ttgctgtact agacttggga tgacactaag taaaatccaa ataattgctg
    39481 caactaaaag gagcagcaca attgcgacag cccatattct tttgattttt gctttcatca
    39541 acagcttgac aataggattc aataaatagt aaagaaagcc tgcaatcagt acaggtgcaa
    39601 ataacgtgga aaaaaatgtc ccgatcggtt cgaaaataaa gtttatttct gatgaaatca
    39661 tgatcaatgc agctatgatc aataattcaa gcgaccaaaa cattagttta gactgtctaa
    39721 gtttttcaaa caatagattt cctcctttct t
//
LOCUS       DAFLWQ010000018        39642 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.019, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000018 DAFLWQ010000000
VERSION     DAFLWQ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39642
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.019"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(58..603)
                     /locus_tag="L1V16_000943"
     CDS             complement(58..603)
                     /locus_tag="L1V16_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBN1275300.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(615..1307)
                     /locus_tag="L1V16_000944"
     CDS             complement(615..1307)
                     /locus_tag="L1V16_000944"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBN1275301.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1326..1610)
                     /locus_tag="L1V16_000945"
     CDS             complement(1326..1610)
                     /locus_tag="L1V16_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275302.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1623..2186)
                     /locus_tag="L1V16_000946"
     CDS             complement(1623..2186)
                     /locus_tag="L1V16_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBN1275303.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2414..3076
                     /locus_tag="L1V16_000947"
     CDS             2414..3076
                     /locus_tag="L1V16_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBN1275304.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3200..4396
                     /locus_tag="L1V16_000948"
     CDS             3200..4396
                     /locus_tag="L1V16_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBN1275305.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4497..5873)
                     /locus_tag="L1V16_000949"
     CDS             complement(4497..5873)
                     /locus_tag="L1V16_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1275306.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(5910..6776)
                     /locus_tag="L1V16_000950"
     CDS             complement(5910..6776)
                     /locus_tag="L1V16_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HBN1275307.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(6865..7890)
                     /locus_tag="L1V16_000951"
     CDS             complement(6865..7890)
                     /locus_tag="L1V16_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBN1275308.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(7908..8582)
                     /locus_tag="L1V16_000952"
     CDS             complement(7908..8582)
                     /locus_tag="L1V16_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1275309.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(8766..9659)
                     /locus_tag="L1V16_000953"
     CDS             complement(8766..9659)
                     /locus_tag="L1V16_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1275310.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9733..11430)
                     /locus_tag="L1V16_000954"
     CDS             complement(9733..11430)
                     /locus_tag="L1V16_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBN1275311.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(11423..12736)
                     /locus_tag="L1V16_000955"
     CDS             complement(11423..12736)
                     /locus_tag="L1V16_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBN1275312.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(12736..16773)
                     /locus_tag="L1V16_000956"
     CDS             complement(12736..16773)
                     /locus_tag="L1V16_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBN1275313.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(16786..17244)
                     /locus_tag="L1V16_000957"
     CDS             complement(16786..17244)
                     /locus_tag="L1V16_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBN1275314.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(17542..18060)
                     /locus_tag="L1V16_000958"
     CDS             complement(17542..18060)
                     /locus_tag="L1V16_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBN1275315.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(18062..18679)
                     /locus_tag="L1V16_000959"
     CDS             complement(18062..18679)
                     /locus_tag="L1V16_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBN1275316.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(18676..19530)
                     /locus_tag="L1V16_000960"
     CDS             complement(18676..19530)
                     /locus_tag="L1V16_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1275317.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(19527..20438)
                     /locus_tag="L1V16_000961"
     CDS             complement(19527..20438)
                     /locus_tag="L1V16_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1275318.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(20479..21813)
                     /locus_tag="L1V16_000962"
     CDS             complement(20479..21813)
                     /locus_tag="L1V16_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1275319.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            22021..22851
                     /locus_tag="L1V16_000963"
     CDS             22021..22851
                     /locus_tag="L1V16_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBN1275320.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(23095..23413)
                     /locus_tag="L1V16_000964"
                     /pseudo
     CDS             complement(23095..23413)
                     /locus_tag="L1V16_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(23535..23729)
                     /locus_tag="L1V16_000965"
     CDS             complement(23535..23729)
                     /locus_tag="L1V16_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275321.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(24234..24419)
                     /locus_tag="L1V16_000966"
     CDS             complement(24234..24419)
                     /locus_tag="L1V16_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275322.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(25269..25610)
                     /locus_tag="L1V16_000967"
     CDS             complement(25269..25610)
                     /locus_tag="L1V16_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBN1275323.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(25610..25840)
                     /locus_tag="L1V16_000968"
     CDS             complement(25610..25840)
                     /locus_tag="L1V16_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBN1275324.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            26127..26465
                     /locus_tag="L1V16_000969"
     CDS             26127..26465
                     /locus_tag="L1V16_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275325.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(26670..26909)
                     /locus_tag="L1V16_000970"
     CDS             complement(26670..26909)
                     /locus_tag="L1V16_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBN1275326.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(26885..27232)
                     /locus_tag="L1V16_000971"
     CDS             complement(26885..27232)
                     /locus_tag="L1V16_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBN1275327.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(27964..28545)
                     /locus_tag="L1V16_000972"
     CDS             complement(27964..28545)
                     /locus_tag="L1V16_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1275328.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(28728..29354)
                     /locus_tag="L1V16_000973"
     CDS             complement(28728..29354)
                     /locus_tag="L1V16_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBN1275329.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(29376..30707)
                     /locus_tag="L1V16_000974"
     CDS             complement(29376..30707)
                     /locus_tag="L1V16_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HBN1275330.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(30862..31263)
                     /locus_tag="L1V16_000975"
     CDS             complement(30862..31263)
                     /locus_tag="L1V16_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBN1275331.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(31349..31555)
                     /locus_tag="L1V16_000976"
     CDS             complement(31349..31555)
                     /locus_tag="L1V16_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275332.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(31650..33152)
                     /locus_tag="L1V16_000977"
     CDS             complement(31650..33152)
                     /locus_tag="L1V16_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBN1275333.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(33170..33625)
                     /gene="argR"
                     /locus_tag="L1V16_000978"
     CDS             complement(33170..33625)
                     /gene="argR"
                     /locus_tag="L1V16_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBN1275334.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(33723..34340)
                     /locus_tag="L1V16_000979"
     CDS             complement(33723..34340)
                     /locus_tag="L1V16_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBN1275335.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            34561..35934
                     /locus_tag="L1V16_000980"
     CDS             34561..35934
                     /locus_tag="L1V16_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1275336.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            36009..37121
                     /locus_tag="L1V16_000981"
     CDS             36009..37121
                     /locus_tag="L1V16_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBN1275337.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(37193..38830)
                     /locus_tag="L1V16_000982"
     CDS             complement(37193..38830)
                     /locus_tag="L1V16_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HBN1275338.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(38998..39606)
                     /locus_tag="L1V16_000983"
     CDS             complement(38998..39606)
                     /locus_tag="L1V16_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBN1275339.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT        11371 a         8437 c         6886 g        12948 t
ORIGIN      
        1 tttatgctct tcttttatta ttttgtgctt tttattttat caaatcactt tgttttttta
       61 taaaatttct gcgcctagtg tggactcaaa atgtctcaat gcccattcat gtccaacggg
      121 atcgaaactt gccacggaat ctttgaaaat atggagtttg tatcctagat tatacgcatc
      181 gactgctgta tgcaacacac agatatctgt acatacgccg gtcaaataaa tatctgtgat
      241 ctggcgttct cgcaaacgga tgtctagatc tgttccacta aaagcggaat aatgccgttt
      301 gtctatccaa taaacatttt cctcttgctc atagtcttgg tataaacttt ttaaagagcc
      361 gtacaattcc cgtccacccg ttcctatcac attatgcgga ggaaataagc ggttctccgg
      421 atgaaaggaa tcttttggat catgcgcatc aatggcaaaa acgacaaaat ccttttgatc
      481 aataaacttc tttgtatgag cagtcagctt tttttcaatt acttgtcctg ctgtcccagt
      541 agtcagcttt ccatcctctg caacaaaatc atatgtgtag tcaatcgaga tcaatgcgtt
      601 catcttagtc ctccttatac gagatgtttg acaaattcga tcaccatttc tgctgatcgt
      661 ttgcctgcgt cttcgataaa ttcgtcaaag ctttgtgtcg ccgagtgatc tgctgtgtcg
      721 ctcattgcac gtacgatcaa aaatgggata ttgaactgac gagctgtttg tccaacagcg
      781 gctccttcca tttcgcaagc taatgcttca gggaaattcg ttaagatttc tttgatttta
      841 tctggcgagt cgacaaatgt atcacctgta acgatcaatc cttcttttgc gttcaaattc
      901 gttgcttttg ctgctttaac catttcactg cgcaaatatg tgcttgcttc ataatataga
      961 ggcattcctg gtaattgtcc tgggttgtag ccaaatcctg ttgcatctgc atcaaaataa
     1021 gctactttgt ctgatataac gatgtcacct acttgtaagc cttcaccgat tccgccagct
     1081 gaacctgtat tgatcaccat gttcacgccg tattgttgga tcaacagact tgtggtaata
     1141 gatgctaaga cttttcctat accggaacgt acgacgatca cttcgtggtt acctaatgaa
     1201 cctgaaataa ataaagcgcc tgcgcgttcc catgataatg gttcgcttag gttctctctc
     1261 aaaattttta cttcttcttc cattgcgccg ataataccga ttttcatctt tttaattcct
     1321 tctttctata taaatgcgat tgctaaaaaa accacacata acattaggat aacaataata
     1381 agagatttca tcaaaaaaga gttccatttg gtcgtctttt cccgttcgct gatccttgtt
     1441 ttcgtgattg gtttattctt tttgctttct ttacgataaa agctggcaat ctttttttct
     1501 tcttgctgat aagctgtttc tgcttttcgc tgttttttta atgactcgct tgcttgtgct
     1561 tgttgtcgct tgcgaagttc gcttcgcgta ataagcggtc ctttggccat aagccgatcc
     1621 ctctactttc ctttggtcaa tagttcccag tattgaatcg cataaatcgt ctttgcatca
     1681 caaatcaact gatctttcat cgcttgttgc gcctcttcaa gagttagatg atacaactcc
     1741 agtacttcgt cttcatcttg tgctaaagga ttctcgacct tctctacccc ttgtgcatga
     1801 taaatatgaa ggacttcatt tgcaaaacct ggtgaaagat acatcgaagt aagatggctc
     1861 agcgacttcg cacgatagcc agtttcttct tctaattctc tagctgctgt catttcggga
     1921 ttttgtcctt ctcctggatc gatttttcca gctggaatct ccaaaatcac tttttctaaa
     1981 ggttttcgaa attgtttgac aagaagcaga cgatcttgtt cgtcaaaagc aatgatcccg
     2041 acaccgccag gatgaaatac cagttctctc ttcgaagttc ctccatctgg caaacgaact
     2101 tcgtctacag caacatcaat aatttttccg ctatagattt ctttgcgact gattgttttt
     2161 tcttcaaatt gctcattgtt cagcatatct tctcctgctt tctttgtaat cataactgct
     2221 tttttttcat ttttcaattt ttctcaaaaa ctccttatta gtttaccata gataaacctt
     2281 agattttctc taaatataga aaatccttct ttagtccgat actctttcta gtagtccgta
     2341 tgctaaaata agtatgtaat cgaataacga aaagaattca atactcaacg ataaatgaca
     2401 tggagggttt attatgataa aacgaaattg gccgtggctt ctagcattgg tcttgctatt
     2461 tctctttgtc cgaaacaata gtttttcttt tgttctagga cttttattga taggtgtagt
     2521 tttagttttg tggggactct ttggttcgcg caggaaaaag ggaaaacaag aagaaattcc
     2581 tgcactgact gacgaacttg aaactcacta tgaaaaaagc ggtatgacag cgaatgaaat
     2641 ttcatttttt cgacaaacaa tgaatcaaac aaaaaatgag atcaatcaat tgcaaatgaa
     2701 tatgcagcag acagccaaac ttaaagcaat cgatctccgc catgatccag tcaaagcagc
     2761 gaaagcttta ttcaaagaat tggtgaaaga accaaaccga ctgcatgaag caagtcagtt
     2821 tctttatacg catctgccga atctagttga tttgacaaat aagtataatg agatcaatga
     2881 ccatgagatc aaaaacaaac agacctatga aaaactagaa gaaagcgcgc agatcatcga
     2941 ccagctgtca gctttaatcg cacaagatta tcaaaaattc gttgctgagg atctagatga
     3001 tatcgacgta gagatatctg ttgcgaaaca gagcttaaag cgtgataata aatatgaacc
     3061 agaacaaaag gattaactct tttgttcata aaagaagact cggaacattc agatgatgtc
     3121 tggctgtttc gagtactttt tctaaagtag agacattcat gtaagaatcg agaacagatt
     3181 caacaaggag gaatttttta tggatcataa accgactgaa acaaaagatg ttacaccagt
     3241 taacgataca cttgaagatt tattgaacaa cccgttttca actccaacag atacgctgac
     3301 cacttcacaa caagcggaga ttgatcagct ccaagagcaa cagacagctg ctcgtttaat
     3361 tgacaaacta ccggcggaac gccaagaaca agctaaacag ctagcagcaa aaatcgatgc
     3421 taatgatgca cagtctgtca tcagctacgg atcggctgcc caagcaaaat taagtgaatt
     3481 ctcacaatcg atgttgaatc atgtgcaagc acaagatatt ggtcctgtag gagattcctt
     3541 aactgaactg atgtatcgtc tccaagaagc caatcctgac gaactgcgtg ccggagaagg
     3601 gaacatcttc cagcgtgtct tcgggaaggt caaacaatcg atctatgaag tgacagcaaa
     3661 atatcaaaag attggtgcac aaattgacaa gatttcagtg aaattagata aagaaaaaga
     3721 cggtctgcta aaagataatc tgatgttaga acagctttac cagaaaaaca aagactactt
     3781 tgatgcactg aatatttata tcgctgctgg agaattgaaa atggaagaac ttcaaacaac
     3841 gatcattcca gaagcgatga aaagagcaga agaaactggc gatcagatgg atgttcagat
     3901 tgccaatgat tacacgcaat tcctagatcg tctggataaa cgtacgcatg atcttcgctt
     3961 agctagacag atcacgatcc agcaagcacc acaaatccgt ttgatccaaa acacaaatca
     4021 ggccttggct gaaaagatcc aagcatctat cgctacagcc attccgctgt ggaaaaacca
     4081 agtcgtgatc gcattgacct tgcttcgtca aaaagatgca gtaactgctc aacgccaagt
     4141 ctctgaaaca acaaacgact tattgaagaa aaattcagaa atgctgaaaa tctcagccat
     4201 cgaaacagcg aaagaaaatg aacgtggaat cgtggatatc gagacccttc aaaccactca
     4261 aaatgatttg atcgaaacaa tccaagagac attgcgtatc caaaaagaag gaaaagaaaa
     4321 acgtcgtcat gcagaagtag agcttggaca catggaagaa gatctgaaac aaaaactgtt
     4381 ggatttaacc caatagatca cctttcgctt gttactaaaa caaacgccca acaacagttt
     4441 attacaactg ttgatgggcg tttttcttat ctttcttcta acttctccat tggagtctat
     4501 ttctcattca tcttgctgtg tccatagcca tagccaaaat aaatgatcag tccaataacc
     4561 attacgatac cgaacacgat ccatgtcaca gtttgcagac gaagcatcaa tacaatacaa
     4621 gtcaaaatgg agacgattgg caatagcgga acgaatggca ctttgaattc tccagctttt
     4681 ggtttgccaa acatttttct caacttcagt aagcctagac taacaagcat caaataggcg
     4741 agcgccatga tattcgttag ttccgctaat acattcaatg ggaaaaatcc ggcaaagaat
     4801 acagctgcca caccagcggc ataagtcgct tttttcggtg tacgatgctt ttgatcgatt
     4861 tctgtcataa acttaggaag taagccatcc ttgctgacag caaacagtaa acgagcaagt
     4921 gaatacatca tcgagatcgt taccgtcagt agcgttaaaa ttgcccctac agcgatcacc
     4981 gcgcccactg ttccatgtcc tacatacctc attgcaaaag ccactgggtc attgactcct
     5041 agttcagtat acggaacgat tcctgtcaag atcagcgtca cgatgatgta aaggacagta
     5101 gcaatcagta tcgaaccaat gattcctctt ggcacatctt tttgcgggtt tttgacttcc
     5161 tcggctgcca ttgcaacggc atcaaatccc aagaaagcaa aaaacacaag agctgcacca
     5221 tctagcacac cggaaaaacc aaaaggcatg aatggctgcc agttatcagg tttaacgaaa
     5281 aatattccta caatgataaa caacgcgatg ataccaaatt tgacatatac catggcatta
     5341 ttcaaacgta atgctttctt ggcttcaagc gacacgatgt aagtgacgaa tatcactacg
     5401 agcaccgcaa tcaagtcaat gtatgtacca ttttccggat tgtacccgcc agttaatgct
     5461 tgtggaagtt cggcccctaa acttttcaaa aaaccttgca tatagccaga ccatccggaa
     5521 gcaacagagg aaaccgctag taaaaattcc ccgatcaaca accaccctgt cagccaggca
     5581 gcaaattcac caaatacaac atacagatag gcatatggcc caccaatcac tggcactcgc
     5641 gaagcaaatt ctgcgaaact tagtccagac aaaatgacaa cgattgcagc taagacaaat
     5701 gaaagtgaca gtgctggacc agcattttga ttggccgcaa cccctgtcac cacaaatatt
     5761 cccgtaccga tgatcgcacc aattccaagc atgatcaaat cagacgtttt tagttctttt
     5821 ttcatctcac tcgtatgatt gagattgatc tctttcttac gaaacaaatc cattgaagtt
     5881 cctccccatt ttaggttgga aaacagcgat taaactgttt tcatataccc taaaaggata
     5941 ccacctaaaa tgactaaaag gcaaccaaca ataacataaa tgagctcttt tttcgttttt
     6001 ctttcgccaa ggatgaaaat cccacctaaa gtagagataa tgatccccat ttgtgaaagt
     6061 gagaagccaa cagctaaacc aagtgatttg actgttagaa gcatgcagat gtttcctaag
     6121 ccccataata atccacagat catgtttttc cacacaaact gatcgacttt aactttacgg
     6181 aaagcaaaga agcttgcgcc taagatcatt ccgatacttt gaggtaagat aattgacatc
     6241 gcatccaaat tcgcccagtt gacgatgatg gtatatacac cataaccaat cgtagagaag
     6301 atcaatgctc taaaaccctt accaaaatca agcattttat tatctgtatc tatttttcct
     6361 tcgtcatctt gtcgggcagt caaatacgca ccgcttacaa gaagagctaa agcaataata
     6421 ccgtatacat aatctttcgt ttgtgtccat tcatggaaga aaacggctcc cgcaatcgta
     6481 ttcaaaatta attgaaaacc agtagacaat ggtagcccta cagaaacacc catgtacttc
     6541 attccatgga actgtccatt ttgtccaaca ctccaagcta agccggataa aaatccgatc
     6601 aagaaaatcc aaggggtgat tacaggacta acaacgaaaa agacaactaa agaaaacaga
     6661 aatgcaccga tcgtcattcc tagtgtttgt tgattggcat cgccaccaat tttaccactt
     6721 actaaaccaa tactacccca tgccaacata gggactaatg ctattaaaat ttccataacc
     6781 aatctccttt tatttcacat gataagaaac ttatcagcga aaacgttaac aacacaagca
     6841 ctttttttcg tttctaacga ttttctaacg tttttcatta taaaaattta agattgggaa
     6901 aaataaagtc attgttgtcc cttttccttc agttgattca gccgtcaaat ggatacctaa
     6961 tttttcggcc agattttttg ctaaataaag tcctaatcct gttgaatgtg ttttgctaag
     7021 tcgaccattt ctcccagtaa atcccttatc aaagatccgt ttcaagtctt ccgctgggat
     7081 accgatccct gaatctttaa ctgaaaggct gactccttgc gcttcctttt ctatgctcac
     7141 aatgatgttt ccgtgatccg gcgtatattt gatggcatta ctaagcaatt ggttgaagat
     7201 aaaagcgatc catttagcat cggtcaaaac agtatgatcc tcaccaacga tctcgtagcg
     7261 aatatttttt tggataaaat aatttgcctg actgcgtatc acaggctgaa tgattccttt
     7321 tagtccatat tcttggatga ggtagtcccg cgagaaactg tcgagtcttg cataatacaa
     7381 aacttgttct acgtattcat cgatttttga taattcattt tctagtaatg tatacttttg
     7441 atcgtcaata tcgaactcga tcgaacgaac tagcaattta gaagcggaaa gtggcacttt
     7501 gatttcatgg acccatgagt caatataatc tttttggtct tgttgattac tgattgctga
     7561 ttgcattact tcttggtgtt cacggatcag ctgattgata tattcttcta ccagtttttc
     7621 ttcttctgtc ctcccaccac tcaaataatt ttgcaaaggg gaagtttttt gtatgtcggc
     7681 taattttccc caccatcttc tcttgctcaa gtaaccaccc agcagataaa aaatcagaaa
     7741 gacgccctca atcaaagcta aataagcaat tgtgctcaaa tcaactttga tgtttggcgc
     7801 cagccacatc acaaagatcg tcaatgcaat aaaaaacagc catcccaaga tcaatgtcca
     7861 ctgatctttc aaatatttaa aaaaattcat cttaaccgct catcctttca gggaacgata
     7921 tatccctgtc ctacttttgt ttcgatatat ccttggatac ctgcctgttc gatttttcgg
     7981 cgtaaccgat tgatgttgac tgtcaatgta ttgtcatcta caaatcgttc gtcatcccac
     8041 agtgctcgca gcaatttttc ccgacttaag atctttccat tgtgcttcat caaaataaat
     8101 aatagacgat attcattttt gctcaaatca atgatctctc cgttgatttc catacttccg
     8161 ttgtcaacat tcaacgtaat gccattgtgg ctcatcattt cactagataa ttctgtgtag
     8221 ttgtaagaac ggcgaagtaa tgcattgatt tttgcaatca gtacatcgat ttggaaatgt
     8281 tttgtcacaa aatcatctgc ccccatgttc atagccatga tcatatccat attcgtattc
     8341 ctgctggaga taaaaatgat cggtactttc gatacttcac gtattttttg acaccaataa
     8401 tagccatcca aaacgggaag attaatatct agtaatacaa gctgtggttc ttctctttca
     8461 aagtctgaga acacttgatt gaaatcggtc gttccaaagg tttcaaattg ccatttctca
     8521 agttcctcca tgatcaattg tcgaatgatc tcttcgtctt cgactaccat gatttttgcc
     8581 ataaaaaatc cctccatctt tcttcttgct actacaatat caaagaagcc cttgtgaaac
     8641 aagttggctt acctggaaaa tgtcatttta gcaaacgtta aaaaaaactg gaaatatgcg
     8701 atttaatcgc gtttgtctct tccaagcagc ttaaatttat tatgttattc ttaataattg
     8761 gtctattatc tgttattttt ctttcgttgt ttttgtcttt taaattttcg ataacaccaa
     8821 taaccgaaaa gcgttagcac tagcaatata cctagaagga gtataagtaa tcgataaaga
     8881 tggtattttt ttgtctgttc tatctttgaa gagacttctt ctgtaaaggg aactcgtctt
     8941 cctgtcacta gtaatcggtg agtgttcacg gtgtaaggtg tacaagtgat aagtgtgact
     9001 agatcctgct tttctctaat tgctaatgta tttgtttttg ttggaaggac aacaattttc
     9061 tcaacgactt cataagcgag catccgacca tacacttcaa gatagaatcg gtcatcttgc
     9121 tccatttctt caagatccgt aaagagtttt ttctcagcaa taccgctatg ggcggtaatc
     9181 acggaatgtg tactctctcc tccagttgga aaagaggtgc cttgcaggac tgtcgctcct
     9241 ctatctaaca aaagatcatt cgtttcatca aataaaggca agctaacatt gattttcgga
     9301 atatagatgg ctccgatcat atgttgttcg taatattctt ttcctggatt ttggacattt
     9361 ctaaccgctt gctcaaaagg atctttgact tgtcccattc ctgggattac tgatgtatga
     9421 gcaagcgtct gatttttctt ttcatgcact gctaattgtt gctcatgttt ttcttcttta
     9481 tcgcgttcaa gctgcttttg ataattctcg atccttcttt gatccaaata attgctgaga
     9541 gcatctgcta aaaatggata tgtaaaaact gcagctccgg caagaaacat cactgccata
     9601 aataattgta ataaaagact gatttgggtt tgaggtctat tacctatttt ctttttcatt
     9661 ttcttcacct tcttatttaa aaaaactgca gcaaccttta taaaaccgat tgctgcagct
     9721 tatttttgtt gcttatactt cagacttcat tttagattta cggtaccagc tgtacgctcc
     9781 aatcatcaaa cttattccga ttagtaagaa tgccaagagc ccgttcccac cagtagcagg
     9841 aagtgacccg cgtttcatat tcggtactct ttctggccct ggattttcta ctcctacgat
     9901 ctgaatttct tcattatagc ttccataaga gatgataaat tcagtaaagg ctgcctcacc
     9961 tgttggaagt acataacctt ctggcgccat ggtctctttc atttgatagg ttccataatc
    10021 taacccttga acctcaaagt atccatttcc atctgcgaca aattctgttg cttgtccgct
    10081 tgttgcccac tcaattctat ctgctcctga ttcataaaca gctaaaggcg actccccttt
    10141 ataaaatatt gcgtattcag aacggtcttc attccacaat tcgaatcttg catctttaag
    10201 caattcactg cttgatgcat catatttttc aaactttctt ccacctgttg tgactttctc
    10261 tggcggctct actccttctt cataatcaaa ttcatcattt cgtccgattt caataaccgc
    10321 tgtgttgtta tggaaatcat ccgcttctag ttctgtggaa accttcaaat tatacgtgat
    10381 cgttaaatct cctccacgtg catctgctaa tctacctaaa gtatctactt tggctactcc
    10441 attttcttct gtcaaaatcg tcacgacaaa cccgttgctt actacttcta ctatataatc
    10501 ttgtcctttt gttaaaatcg tctcgccggc tcgcacttct atttcctgat cataataagt
    10561 tagaccaact gtaggcgtat ctgtgatttt gtaatttttg ataacagcgc ttccgttttc
    10621 aaggacagaa tcgatgaaat aaggaatagg tgctgtgatc gtgtaagaag ccgtttttcc
    10681 tctttctaga tcaatataag aaatcgtttc ttgttctcca gcttcattaa taatcgttac
    10741 ttgtctaagg tcgctttcct ctacattcat ctgtttatct gcttctctga tttcgttttt
    10801 cggatacaaa tgcacatctg tattgtatgt gtctttccat gtagaaccat cccacacgcc
    10861 atccaccata tcaggcatca tcactggcat cataacaacc attggagacg cgattctgga
    10921 aatatgagct ggcgaataag tttctaagaa aagatagact ttatctctag aagaaggtgc
    10981 ttcttccgtc acttggacgg tagagaatac cgcttctcca gcttcattcg ttgtttgttt
    11041 gtcaatactt gtcagtcgat attttaaaaa ccaactttct gtgtgccgtt tttgaatcca
    11101 ttcaatcgct tcggcagaat taagaccgtc ttctcgttcc ggtgttaaag gattatctcg
    11161 aatcaaatcg taatatactt ccgttacgtc aaacaaatca aaatcgactc ctggaatatt
    11221 ttcttcacca aaatccgtag aaaccaatcc gctattcggt cgttcttccg gaacagatga
    11281 gaaacctttt ttgtgtaatg taatcgtcac ttcacttggt ttttgtgcga cttcttcggc
    11341 tttgactagt tttccgttcc cgaaaatccc tattcccgca gtaacgagta acagtacact
    11401 cattcccgtg acaatcattt ttttattcat ttttttctcc ccgttctttt tttattaata
    11461 aaacagcacc taacaataaa agaattccta gtaaagaaat caacgttctt gcttcattcg
    11521 tttgcgggaa tacggaccat tttcctgatt gacctggatt gcttggacca ctcggctctt
    11581 tcggtttgtc cgttgtttct tttacggtct cgttataaac acgtggtgtt gcggattcat
    11641 aggcagagac tggaactttc ccggattcta attcagccat ctcctgtccg ttaactacta
    11701 catattgtgg ttggcctttt gcatccaccc aaaattcagg gatgatgacc tcgattctct
    11761 tacttgcttc atccatctcg taaccttcca caccttttaa ttcttcaaaa taataggtgc
    11821 cagaaggcaa gaaacgttgt cctgtcgtaa caaggccctc tttatccgaa atgaatttgc
    11881 ttacattttt gtcattcaaa ggatcattgt ctgctggttt gatccattga tttttcaagt
    11941 cattagcagg agccatatct aaataatatt tccccccttc tatcatctga tatagagcaa
    12001 aaacagcacc ttctaatggt tttccttttt cagttgttcc tctttgacgt ccatacttga
    12061 agaagtatgg atctcttaga taaccgacat ttttaggata gatatgaatc tcttgcagtt
    12121 cctcggttga ttctgtcggg tgataaattg gcaaaatagc agcaattggg atagctgtct
    12181 gatcgatatc aacatccaat ccaacttctg gatcaatcga ttcttcgaaa atcaaataaa
    12241 ctgcatcccg atcttggttt ttcttaggtg ctttgatacg tgcaatcccg tctcctaatc
    12301 cgccaaccgt atctttccca gttgttaccg aagtccctat ttggacaagc ctttcttctg
    12361 tgattagctg acggatattg tttctgttcg tttcagcgat ttgctggacg aattctttag
    12421 gagtcatgtt ttcagcagct tttttttcat gataataatc ggtcatgtcg taaatggcaa
    12481 atgtcgctcc atttagtggc accgtctgtg aaatgatatc tgctgtttcc cctgcttcct
    12541 cagagatagc caagccatca ttttcatggt attcaaattg atcgttataa tcgatatctc
    12601 gaatcatccg tttatgcaac acgaattcca cgacatcttc ccctgattct tctgccgaca
    12661 tcgcatgtgg aagaaggact gctgcaagcg gtagtaaaac aagtaattga agcatcaaac
    12721 acaacagctt tttcattacc ttgctccctc ctttttagat tgtctgacaa acaaaccata
    12781 ggctgctcct gcaagcgcca tgaagaatgc agcaagcagg atatagaata atcgtccgga
    12841 tcctcctgta gcaggcaacg gattttcagg atcgttcccg acactaagct gtaatctgat
    12901 tcgatttgtc tccaaaagtt catattctaa ctcttgctgt agatcaggcg tctctgcttc
    12961 ttcgtttgga taatacgaaa tctcaacttt tagtgtaccc gcttcttttc ctggaactac
    13021 ccgatcattt tctatgtcag gttcttctcg ataactaatt tctaaaataa agtaacctgg
    13081 aagttttcta tagctgtcag gtgacttcac ttccttgatc cgatagaccc cttccaacaa
    13141 gtctgaagca ttgaataggg aagaatcgtt tggatctggt gccaagcctc cctcgatgat
    13201 ttcatactct cctgcactat tttgtttctc aattgaaaat tctgcgcctt caagacgtcg
    13261 gctattcata ctgtcaattt tcaaaagttc caaatcgatt ggcgctagtt catcttctaa
    13321 ggttacttgt agtacaccat cgatgatttc atagccttcc ggcaagggag cagtttcgtc
    13381 ttcgatgacc gtatcttcaa tgataaactt accttcttca ttcagtgcaa actggaacac
    13441 ttgatcagat agccgatacc catttggtgc gacagattcc gagacctcat attcaccaat
    13501 agacagatgc agaggttggt cgtaatttaa atcgacatac ttttctactc ctacggcacg
    13561 agaatagaag tatccgatcc caggcaaacg tttcgattct tctggttcta acggattacc
    13621 agtgtatgct cgatacagcg ggaaggaaga atcccccact ttcctgatat cgaaacctgc
    13681 accatctaat gtatggcctt catggtctaa ttttctaact cggatctccc gataatcaaa
    13741 cgtattgtaa gcagtgaatg ctacccataa acgatcctct tcatctgttg tatacgtgag
    13801 atattgccaa ttttcttcac ctgtttgctt gagttggata gtccctatag cattatcgta
    13861 aagtcgcaag atccatgtgt cattttcatc aggttctttg aaaccttctg ggttctggct
    13921 ctcaatgatt ttgtattctg catagttggt agtttcttca ctatccttat aaacaaatga
    13981 atctggctct ccgattggat gaataacttt ctcaccatcc acgattacat atttcccgtc
    14041 ttcatctact gaatagaacg tgagtctccc tttctcttcc tctacttcgt tcacaccaga
    14101 aagccctttc gctactggat atccgatttc cagtccgtta ccatctgttt cataaagttc
    14161 aaactctgcg ccattgattg gcatattact gccttcaatt agtttattga tattcatgtg
    14221 gattggcttg aattcatttc gcatttccag tttgacatac aactcatcat actctgtgcc
    14281 ttctatgtta ggctcttgta caacagaaag cttgtgatat tctccttcat aataggaatt
    14341 cggatcttta ccttccggtc cgccgactct cgaaccagat gtatattcat ctacaagctc
    14401 gtagtgacct aacatctcat cttcgttggc tgcatatttt ttgatttgga attgatacgt
    14461 ctcatctact aactgataac gtggtggtcc agcgatctct ctgatccaaa atatgtcgct
    14521 gactgctcca gtttcatctc ctaaaatcgg catcttcgtt tcaaagatcg ctattccgtc
    14581 cgtggtagtt ttacttgttt cgattggttc ggcttcccca ctctctggat tttggtcata
    14641 taatgcaaat tcgactccag ccaacggctc gccattttga cccttcttgc tgacttggaa
    14701 attacggcct ttatgttcgt aacgaatgga agaagatggg aaatacatcc gtccagtagt
    14761 gatatcattc tcataatcct ccaggttctg aatataggcc atattgttca ctgtgcaaaa
    14821 atttccgtct tgagctcccg catcaagttt tacttggtac ttgatcctga ccatttcccc
    14881 ttcacctaaa gaaatcggag aaaatttata agcttggttt tcccgtccga catacgttgt
    14941 cggagtcgcc actacttctg gtggggcttg tccatgacgt tcttcatccc atatttctgg
    15001 ctcttggtac ttcatgccgt tttctcctgg atctagatgg taaaactgaa tatctgccga
    15061 tctgccagct ccaaatggtg agacattaaa accagtttca tcataaagtg tggcttgctg
    15121 gatcgttctc ttgaaggtag aagagatatc ctccaaggct gtaacaatgt cattcttgtt
    15181 gttcgcattg taatatcgcg gtgttacgcc atcttcttct aaatcagcaa tatttttcaa
    15241 tacatttcgt ccaatagcat ctagtcgttg tctcccgcta acgtttccat cgattcctaa
    15301 accaatggag aagatacttg gcgggttctc ttgatacttg tttttcagcc aatgatgata
    15361 agcaactgtg ttgatcgcag atgacttttc ttgcgaagta ggactgccat tcgtattgtt
    15421 attagaagaa ccatcaccaa cccagtgagt cgctttatta tctccttctt ttacctctcc
    15481 ataacgatag tgtacattta cttcatcttc tggacggtta aagtcagatg cataggtaac
    15541 tggatgagta aaccctgcat tagaagtatt cccagaaaac tcctcaaaat ttctgaacaa
    15601 aacgtcatta tcttcagcaa tcttatcttc catcacagtc cagttgctcc aagctccatt
    15661 agtgctcgta cgataacttg actgaatcgg tgcataactg aaggtcggtg tcccatctcc
    15721 cacaacgatt aggatttttt ctggatttct attttctccg ccattgtctt tatacaatgt
    15781 ttcatagcca tttttaagcc ctagtgtaag cggagttcct ccgattggtg tacgatttaa
    15841 tgctgtattc tcacttcccg tcaaacgatt gatatcattt gtcaatggaa agatgtccga
    15901 actgatttgc tcatggttat tgatagctgt actattatgg taaaaattca ccataccgat
    15961 tcgaatatcc agactcgggt cagagagcag atctttactc atttcgttta ctgcctcaat
    16021 caacgcagca tttttagttt gactattggt cccagcggtt aattcactca tactcgctga
    16081 cttatctaga acaaaaacga tatcgattgg actgatttcc tttttctcgc ccccgatgac
    16141 atctagatag acattgtaaa gggttgttgc atcttcagga tgtagatcag atgctgtgct
    16201 gcttggcaga acaggttcta cccatttttt gatgtacgcc ccgttataat ccaagtaact
    16261 gttttcaaaa ttccgttcat ttccccaaag ctgaacggtt tgagctggaa cgtttctatc
    16321 ttcttcgcct gcagttgatc cattattagt agcatagtcg taatttcgcc agttcgctcc
    16381 cccgtttgta taatcactat catcgatcaa gttctctccg tcatatggcg agcctttgtc
    16441 tccttgatag cgttcattgc tttgtgtcca atttcctaac acttttgtat agtcattcgt
    16501 tgtaaacttc gggtagcgat gctgttcgtt ttcaacttct ccgctaggat agatatattc
    16561 ataggggtct tgcgtagctg ttggcccaag acgctccaaa ataccgttga ataactggcg
    16621 ttgaatgcgc tggagtgctt gaccgctggg tacgattggt tcgtccagct tttccatctc
    16681 attttcttcg ctacgttgaa tttcagcgga atcttctgta tcagtttcat tttcttgtaa
    16741 ttcttggtta tctattcttt catcaaccac cacttgaaga ggtagttacc cttcgttcac
    16801 atcggggatc ttttctgttt caaaaatcaa tgtgccggtt tctgcttctt ttgaataaac
    16861 ttttccgaca taccattctt gaccatcgat cgtctcgact tttaggtctt ctccatcttc
    16921 atcataggag gatagacctg ttccacgaac gttttttacg gtaccaatcc cggcggctgc
    16981 cgcatcgatt gctaaacgta ttctaccttc attggcactt tccttttttt caaaagccag
    17041 atgccattca agggtttctt ctttttcaat atacttccct tcaatttttg catagtcctc
    17101 atctaagaat acctcatcct cctttgtttc tgttgactca gcagctacat ccagggtcgt
    17161 catatgatag actgactgga aatatggtcc aaatagcaaa ctgacagtta ctaactgcaa
    17221 aagcttcaat tttaaccctt tcacatcctt atactccttt caaaaatatt tgtcttcttt
    17281 cacaacaatc aacaaaacaa tgcccatcta attataattt aatttaattt taattttaaa
    17341 tcaaatgata tcctttttag ttaaaaaaca ccaattatac aacatttatt attaaaatta
    17401 aattataaaa ttttataacg ttctcattta acaaaactta agttattaag acaaatgaat
    17461 aaacaactac gctttcctcg aaacaaaaaa ataaagcaca aatgcgcatt tacgcactca
    17521 tgctttattc gtacaattaa ttcagataac ggcagcgcat aggatgccaa taacacttcc
    17581 taaaatagct cctcctaaaa tgtcagtagg ataatgtaaa agtaaaaaaa tcctcgaata
    17641 agcgatcaaa caagcaaata aaaaggctaa tattcctgca actggactta attcgaacaa
    17701 cgcagctact gataaaaagg ctagcgctgt atgtcctgaa ggaaaagaag aagtcttcgg
    17761 tttacttgtg taaaggacaa gccgacgatt tttttcataa ggtcttttcc gtcttgtcgt
    17821 ttttttgata aaaagcaaac caacaaaaaa atagatcaaa ctgccgataa gaatggctag
    17881 accatattct ctagtatcag gtatcaagac taaaacagca gcaaggagca accaaataaa
    17941 accaccatta gagatattac tgataaattt caaaaaattg atttttcgac tatccgtttt
    18001 ccgttgcttg gcgaacttgt tgataatact atcatcgatt ttagcaatca aacgcaacat
    18061 gttattcctc ctttttaaga accttttctt gcgtacgatg gataaaaagc aggacttgaa
    18121 aataaaacaa gaaactgaaa cctaataaag caaaatagat tggtcctgca aaccagaatg
    18181 cgacaagaag gatcaacgtg cctgccaaat agaaaagcgc gcttttgaaa tcattaaaaa
    18241 acaagaaaaa tgcagtaatc caagaagctt ctttttgttc cagttgaagc aagattttgt
    18301 aactaaagag aagcgcgctt aatagaagca aaaacaacgt agtatacatc aatgtatagc
    18361 caattccccc accccaatag cggaaaatct gataatcgat caatagaaga agaaaataaa
    18421 cacttgctaa actatcttgc tttccataaa gagagaagtt ctcacgaaac tttttccaga
    18481 atagtgaacc gagctttttc tcttcatttt ttttgtaatg ataaatcata tacagaactg
    18541 ttcgacttgc agttcctaat gtgaaaacag gcaagacgca caggaaccat agtagctgta
    18601 aatggataag acgtggaatc cattcaatga tttctaagaa ataatcattg gcttttttac
    18661 caatcgatcg attcatcatc cttttgaacc tcctgtcaaa tccatccctt caatgaaata
    18721 acgttgtgca aaaaagaaca gcaaaatcgt cgggatcaag acaagtgttg ctcctgccat
    18781 cagataattc cattgtgtcg ttgcttggtt ctgaaaaact tgcaagccaa tctgtaacgt
    18841 gtatttttct tgatcttgga tatataacag aggacctaag aaatcattcc aagctgcgtt
    18901 gaaggaattg atcgcaatgg taatcaaggc aggtttcgtc aatggaagca tcaaatgact
    18961 ccaaatatac aaatgattcg ctccgtcgat ttcagcagct tcgatcaatt cattattgat
    19021 cgataagtaa aattgacgca tcagaaatat attgaacgca ttgccgaaga acgatggaac
    19081 gatcaggggc aaataagtac ctacccagcc gatcttggag aataatacat attgagggat
    19141 catcgttaca aaccccggga tcatcatcgt agaaagaacc aaagcaaaca tcagcttttt
    19201 cccaggaaaa tcaagcttcg caaatccata agcaataaaa gaatttgaaa ggacattacc
    19261 gatcactact agcacagtga tgaataatgt atttcttgca tagcgccaaa aaggaaaggc
    19321 ggcaatcgta tccagatagt tttcccatac gattttttct gggaaaaagg tcggaggata
    19381 acgaacgatt tcttccattg gtttcaatga agtaaacacc atccaaagca atggaatgat
    19441 caaaatgatt cctattactg tcatgaggac ataacttagt attttttttg tttgccgatt
    19501 cacactggtc tttttgaaat aatccatcat ttgccgtcac ctccagaata atagacccac
    19561 ttaggtgcaa gcttcaaatt gacaaacgtc agaaccaaca cgatcagaaa caggatcatt
    19621 gacatagcca tcgcataacc catatcaaaa gctacgaacg ccttgttcca catatgcaga
    19681 ttataaaaaa gcaaagaatt tgcaggtccg cctgttccat ttttcgtcat gacataagct
    19741 tcttgaaaaa tttggaaaga accgatcgta gaggtgatca catcgtaaaa aataatagga
    19801 gtgattaatg gcaaagtaat acttttgaac tttccccaaa cgcctgctcc atcgatttct
    19861 gctgattcat ataaagatct aggaacattt tgtaatgtag ctaagtaaag tagcattgct
    19921 cctccagaac tccatatttt catcaaaatc aacgcaggtt tcgtccattg tggatcaaac
    19981 agccaagctg gtccagggat atggaaccag cccagaaatg tgttgatcaa tcctgcagat
    20041 ggagaaagca gctgcatcca taagatgtag actgctactc ctgataagac tgccggtaaa
    20101 tagaaagctg tacggaatac actgattcct ttgatttttt gattgagtac tgtggctaaa
    20161 aacacactga aaatcgtcgt cagcggtaca ttgaagatga cgaaataaac ggtgttgtat
    20221 aacgatttcc aaaataaatc atcgtgaacg aacattcttt tgaaatttgc tagaccaatg
    20281 aaattcatct tggatgtcaa attataatcg gtgaaactac caataactga aaaaagcata
    20341 ggccctagca taaataccaa gaacccgata ataaaaggcg agataaataa ataggcccat
    20401 cttgcttctt ttttctttcg gatagataaa cgcttcaaat tttcttgcct cctctgtacc
    20461 tagacagtca aaaatggatt attgattttg cttgactaag ttttctactg ctttttgtgc
    20521 atctgccaat ccttcttttg gtgattttgt tcctaaaaga atctggtcaa tctgttcatt
    20581 cactaatgtc gtgtaatccg gagcatctaa aggaactggt gtgatcaccg tatttttaaa
    20641 gttttcgtcc gccatttgat agatcatttt tcctttatcc gttaggttgt cattattcac
    20701 taaattctca ttggctgtct tgctcgccat gatatcaaaa cttttttcgc cgaatttttc
    20761 ttgtacttct ggagaagaaa gatatttgat gaattcataa gaggcctcag gatcttttgc
    20821 tccgtatggt acttccaaga cgaatccgcc accccacgac caatggcctg aaccttcttc
    20881 tttttctggg agctgcatca cgccaaaatc aaaatcatcc ggtgcatttt ccatcaaact
    20941 agagtaataa ttgatatttt gggcacgcat ggctactaat ccggaaataa atggatcaga
    21001 tacaccagac ccaaattcgg cttctaattt attgatcgta tttttcccat aataatcttg
    21061 ccagtcttgg atccactcca aggcttccac tttattttta gtatcaatct tgactttttc
    21121 atctttgtca aaccaactag tcccgttatc tgcgtttagc gcccatacat cagcccctaa
    21181 attccataat ggataaaaac cgatgcgtgt aaattctttt ccttcttttt tatctagttt
    21241 acgtgctgtt tcttctaatt catcccaagt tgtcggtaga tcttgttcac tgattccagc
    21301 ttctttaaat aactttttat tataaaaaat gacttgtgta tctgtattga atgggatcgc
    21361 ataaggatca ccttcatatt ctactgtatc ccaaagctgc ggataaaaat ccttagaagt
    21421 gtctttttct acatatttgg agagattagt tgcttgctgt gcttctgctc tttgggcaac
    21481 ggaatttatg tcctgtacaa taacatcggg tgcatttcca gctgttattg cagataaaga
    21541 tttagtccag atgtcacccc atggctgata cttataattt acatggatct cgttttgtga
    21601 ttgattgaaa tcctcaatga tttcttcgat agcttctttt cgtgcaccgg atccccaaaa
    21661 ggaccagaaa tcaatatttt ttcttccatc acttgttttt tcagaagaat ttgctgcact
    21721 tgaactggca tcgcttgcat tacttgatcc gcatcctcct aataaaaaca atgctgaact
    21781 tgccagcaac cctgtaaaca ataatttttt catattttac ctccaaattt taatgtaacc
    21841 gatgccggtt ttaatataac gatatcattt tgttctgaaa ataacaattt ataaggtatg
    21901 attctaaaaa aattattaat gataccaata ctttatataa ttcgcgagcg ctttctttga
    21961 attttttaat ctttcgtagc agaatgagaa tgtattaaaa atagattagg aggaattttg
    22021 atgtttagac accagaaaga attgcagttt gaagcaaaac cagatcgtcc gaatccatta
    22081 atcgcgaaat atctgcagga gctgatcggc ggccaatatg gcgagatgag tgtagctatg
    22141 cagtacctgt tccaaggctg gagctgccga ggagaagaaa aatataaaga tatgctgatg
    22201 gacattgcaa cagaagaaat cggccacgtg gaaatgttgg cgacaatggt tgctcgttta
    22261 ttagagggtg cgcctgttga agatcaagaa gcagcgatgc aaaaagatcc aacaatcggt
    22321 gccattatct ctggaatgaa tccacagcac gcgatcgtag ctggcttagg acctcgtcct
    22381 gctgacagcg tgggcaatcc atggagcggt gcctatatca ttgcgagtgg caacttgtta
    22441 gcagacttta gagctaattt aaatgccgaa tcacaaggaa gacttcaagt agcacgtatt
    22501 tacgaaatga tcgatgatcg tggcgtaaaa gatatgctgt ctgttctcct tgcaagagat
    22561 agctatcatc aaaatctatg ggaatgtgca gtgaaagaat tagaagaaaa agaaggttca
    22621 atcttagtcc caagtacttt cccgcgtgac aaagaacgaa aagacattgc ttatgacttc
    22681 tataacttct cagagggaga ccaaagtagt gaaggttctt gggctagtgg caaagcactg
    22741 gatggcgaag gcgaatatca atggttgaaa gaacctaaga tcgaaggcgc tgcaccaaaa
    22801 ttagaaccag taacaccaaa aatgtatggg acacctccat tcaagaaata aatatctacc
    22861 cgtagaaaca cccgtttttt gttccacacg ctttgtgagc aaaactgact aaagtcatta
    22921 atcataacca cccttcaaaa gggtggtttt ctctagagct ataagctcaa atcaccggcc
    22981 agcgcctaaa gacgctggct ttcatatttt atgttcaagc catattgcct ttgccagttt
    23041 tgcccacctc ttaaaaggtt tatgtactac tccttagccc ttaaaaggat cgtcttactc
    23101 tcgtacactc agcttatcta acgcactatc atgtttttct tgttcttgaa tgtacttttt
    23161 gatggtcgct tcattttgtc ctacttttgt cacatagtat ccttccaccc aaaagtgtcg
    23221 atacccaaat ttatatttta gatttgcaca atctcttgat gatctcctga atattggctc
    23281 gatattgatt ataaattatt tttcttctat actttggtgt gaatacaatg tggtatttac
    23341 acatctactt tgtacgggct aaactatttc cctttattgc tccacccgca tagcaagtgg
    23401 ttttgtattt caatcgctcg gcgcgctcaa ttaggtctaa agacaataaa tctaaaaacc
    23461 cgctgcttca ctgacagaaa caacgggttt tcagaaaaaa atgaaatgaa aaagatctct
    23521 tacggcaatc tattttattt ttttgatttt ttataaatgg aaaatgcttc aagaagtcca
    23581 agaaataaag ccgtataaaa acaagaacct atgaaatctt tatttattag atattcaaca
    23641 gaaatcccga taacactagc caacaatata tttatcagaa gtgtaaaata aggatgcttt
    23701 ttatagaata gaactagtgt tgttttcata gactctcctt tcttcatatt tccaattaat
    23761 cacaaattca cggcattact agaaaaatta aaggggcgca gaagtggaaa aatactcttc
    23821 gactttccct acaaaccagg ccatcttgtg tttaataact ataccaaatc taaggtacct
    23881 ctaaatctaa attccatttg tggcggtgac ctccaatttt taactcttct atctcccatc
    23941 cagtatacat aaccttgata cttcgaccac ttatatatcg aacacacaaa tacctatcca
    24001 ttgcaggagt actacctaac ttagttgcta cttgcatcta aataacagct gaaaagatag
    24061 gacttactct tagtaaagta tctgaactat taatttttaa actatcattt ttatcctcaa
    24121 ctacatgcac atctgttgca acttcacttt ctgtctcatc cagataaatg attaaggaat
    24181 cgggaattgc aatatcttca gctgacgctg gaatagttga gctaaattag tcatcatatc
    24241 tttattataa aataaccaac agcaaaaaat acaatgaaaa acaaacttgg aactaatgta
    24301 tcattaataa atgttgaaaa attcagcaac tcattactgt atgattttag cagcccaacc
    24361 aacatatacc ctataaaagc taataagatg gttaggaatc ctttagaatt tttactcatt
    24421 catagacact tccttaaata acttttatta tagaaggtat tgtaaataat aatattgaca
    24481 aaaagtgact caaaataaaa aaaaccttac attatactgg aatgaactgt attgatagtg
    24541 tacctaaaag ctctactgac ataagatcgt gtaatcggta aagtaatttt attaattata
    24601 cgggatgtaa tcaattagag aataaactaa tcataaaagg tacttttaca ttcataattg
    24661 tcgctttgag attctacttt ggttcactat ctgacccaat tgcacatttt cgatcattac
    24721 aagtattggt gtcgttagaa caactaaata aaaactagcg gtagattttt cagaatctat
    24781 gctaatttct gtatggatgt tccagtgatg gcaaatttct cttttcattg tttttcttgt
    24841 cgcatgatat gcctttttgt gttattcagt taaactatag aaattctttc ctagacagat
    24901 cttgatccca aattttacgt ttttgagcat cgatatagtt taaaatgaca ttactcatat
    24961 ctaaagagtt tagatttttt aggactaaaa ctgtcagttg ttctttttct tctttctgtt
    25021 aaagtattgt cgcgactttt cgtatacgtt aagatatgtc gtgaaaaaac aagttttgtg
    25081 acacaaaaaa acgaatgact tgaggaaatc acctcaatca ttcgtttaaa atgctatata
    25141 ttctttagtt taagatacgg aaattaatgc catcgaccac actagtagaa tgaacgacat
    25201 ttacttggcc tttttttaat ttcgttatgt ttagcatata aaaatattat agagtttact
    25261 tacaatgctt aaaacatata ctgtataatc tgatcaattt tagccatgtc ttgcaatggt
    25321 aagttttcta tttttttgag ttttcgttcc ttaaaatcaa gagattttaa ttgtgtaata
    25381 attacttgtc cttttatatc tagctcttca ggtaatgagt aacgtgtcgg taaattcttt
    25441 atagtggaag taattggaca tatgaccgaa aacattgttt tacggttaaa ttcataacga
    25501 gagacgacta gtcctggtcg tcttttttga atttcttttc ctacggaggg atcaaaatca
    25561 atccatacaa tatcaccttt tttaggaata taaattcttt cttctgacac tataaaattt
    25621 ctctcccttc aggagttaaa tcttcccatt cgtctttctc ataatactcg gcctcttccc
    25681 caccactaaa tggatcttca atttttggaa ctaacgtaat tgttccatca tcagaataca
    25741 caacgatata ttcttggttt tctgaaggtt tctttccgtt atcagaaggt aaagttacca
    25801 ctacagaact tccttgtaat ctagattttg taacaagcat tatcatcact cccttaataa
    25861 aagtatacta tataacacta agtaacgcaa aattcccctt tgtaaactat ctagaaaatt
    25921 gttttgttta aagtatatct tattggatat aaatagaaat aaattgtagc cagttcattt
    25981 tttctttaac taaaaaaata atccaagaaa cattgaacct atggatccaa aagctaccca
    26041 aatactatag ctaacccccc gctaccttca attttgcaga taaaacgctt tgggagaaaa
    26101 tttcaaagac aacaggccat cctatcatgc ccgattataa acaaaaagct ggctattcct
    26161 tttgctctga caaatttcaa ttgggaaagt tcacgaaact agcaggtgaa gaagtttcaa
    26221 ctgttcggat caaagaatgc ccgcttcaaa tagaaacatt ggttcaacga atttcaacta
    26281 gacaagactt tgctattgta gaacgtgaga tcgtagctat ttttgtagaa gaagggattt
    26341 tacatgatcc aactcatatc aatgtggata aatggcaacc tcttatctat aaattcagag
    26401 aatatacaac tgccaaccag tcgttaactt tgaattttag attccaagaa ttcaaagagt
    26461 cataatgata aacatcgtta ggtataaata aaaaagactc gcagcacgag taaaaaacaa
    26521 atagaagcta tacattagaa aggtcgactg tgaccctata gatgcagtat atgcagctta
    26581 tgagcatttc ttctgttctc tttgtttttg ggatctgtgc tgaagtcttt ttcgtttttt
    26641 gccgctcttt ctttgaaaaa tcgattatgt tataccttct ccattactaa ttcaggcatc
    26701 tgctgagtaa tgatttttcg cgcaaaagaa atatctgtta cccaaggttc gatttgttct
    26761 tcagtcaaga caagcggcat tcggtcatgg attggtgcga ctgtgcggtt aggttcagta
    26821 gtcattatga ttgattctgc cattttttca tcctgatggc tacgataaaa accgccaata
    26881 tacactattt tttccttatt tgaaaacata aatttgtctt tttcttcatt ccactcattg
    26941 ggaaaacaca acgattttgc aaaaatggtt gatgaaaggt ctttttttct tctactgtct
    27001 ctgcacgggc attaatcatc aattgtcctt ttttaaatcc ggtaaatccc cacttcatga
    27061 tttccggagt gaggatgttt tcttcctctt ttcttaacgt cacaacaaga tttgacggaa
    27121 aaacttctcc agctgctaat tctgctgcct gcttcggttg tttcgtctgg gcttctcgat
    27181 aataattctg aaggagctct gactctagat caaaaaaata acgaccacac atcctaatcc
    27241 ctcccaatct ttttttctat catacactgc aacaagaagt tcgcaccaac aaaacgcttt
    27301 caatttttgt agaactaaaa aagttgtgac aagtgacaaa ctctccagtg aatggtattc
    27361 tcctgccaac tcctcggtca caagtcacaa tattcaacaa acatgagaag ctgctttttg
    27421 aaattgttcc ttgtgactcg gagtgaaacg gcaggcttac gacctctggg taaacggtgt
    27481 tcaaaagcca gtttctcggt attaagccaa atttatgcaa aaatgtagaa agctattttc
    27541 acaaaatttt tcttaatact cgaaactaag cgactttttc acaacctctt ccttaaacgg
    27601 tgttcaaaag cttgcatctg cggtaataag cccaaccaaa cgaaaaatat gagcagctat
    27661 ttttatttgg ctgttcttat tacttgatgc agggcagctt tttcacaacc tctccactaa
    27721 acggtgttca atcagctaac cttcggtatt agctcaaaaa acggcaaaat atgaggaact
    27781 attttgccgt ttgtttctct aatactcagg tcaaagcgct gatttcacaa cctctaatac
    27841 acggtgttcc agaagtagct tcttcgaaaa ataagccgaa atttcacaaa aatttgagaa
    27901 gcaattttcg taaattcctt cttatttctt gaagctgacc acttctgtca caacctctaa
    27961 ttattaaaga accttttgcg aagttaacaa tctttctttg atcaattgaa aattctgcct
    28021 aagtagtgat agatcctgtg tgactttcaa caataagata cttccctgga tttcagcaat
    28081 caacgctttg gcttgacggt ctgcttcttc atcggacagt ttttcttcag aaagtgccag
    28141 gatattttgt ttcgtatact tgacccattg attgactaat tctagtagca acagacggta
    28201 ttcttcatcc actgtactca actcaataat caaattacct acaggacagc catgataagt
    28261 gatctgtgtc tcatgatcag cgaaaatcca gtccaacatt tcttctaatg cttcttctgg
    28321 ctgttttcca gcatttaaga tgtcttcgaa caattctgtc tgccatacgt ccatatgcgc
    28381 atggatcacc gctagacaaa cttctttttt tgaagaaaag taataataaa attgaccttt
    28441 tcctgtatca gaagctgcta gaatatctcg gattgacgtt tcatgatagc cttttttata
    28501 aataagatct ttggtcgctt ccaagatctt ttcctttgtt ttcaatgata ttctcctttt
    28561 tcatttctca tagtcctata ttatacagta aattcatcat tttttcttct taatcgttta
    28621 aaaaagactg tgccaaatta tctgacacag ccctcactat aaaactgttc tcatatagct
    28681 agatgttcat tgattcaaga actgcgagga caaaagcaat tcctatctta tgatagttgc
    28741 tctaatactt cctctgttgt catcacttga tctgcaataa agccaaagtt cgtcaacgct
    28801 gcatccattg cttcttggcc aggagcacca attgcatctg tcgctaccac aacattgaat
    28861 ccactctcta ccaattcacg catatgggaa tcgctacaca agtttccgtt cattccacca
    28921 agaattactg tgtcgattcc attttttctc aattggagcg ccaaatcatt gctttctggt
    28981 ccaaagattt tatgaggaga gctgatgatc gtattttcat ccaaataagg tttcaattct
    29041 tcgataaaat cggctcctga accttcttcc actgattcat attgactttt tctagcaaac
    29101 atctgctgct caagcatcat atgttctcct gcaccgccaa attgccattt atggtcatgt
    29161 gggtaaaaat aatgaggaga aataaagagt ttgtatcctt tttcttttgc ttgttttacc
    29221 atttcaatca tattttcgat cgtattgtat ttttctaaga tatcttttgt caaaccaaag
    29281 ccaccgcctg ctggtttcaa gaactcgact tgcgggtcag tgagaactac tgctgtattt
    29341 ttattattga acatggtgga ttctccattc gttatttatt ttaatacatc atttagagct
    29401 tcactcattg tcggatgaga atagatttga tctctcaata acgtataagg aagttttcca
    29461 ttcatagcta gcgaaatcaa gttgatgact tcatgagaat cttccgcata gatacttgcc
    29521 cctagaatca agtcagtttc agggtcgact aaaactttga atacaccttt aggatcttct
    29581 aatacttgtg ctttagggac accgcttgtc atatacttga ataatttgta attgacgcct
    29641 tgtgctttgg cttgtttttc tgttaaacct acattggata aagtcggagt gataaataca
    29701 ctgtaaggca cagctttccg gttattcgtt gttcgtttat tctcgccctt caactgatcc
    29761 ataatgattc gataatcatc tagagagata taagtgaact gcaatccgcc tttgacgtct
    29821 ccaatcgccc aaatgttgtc tgcatctgta cgaaggtatt catccacagc gattgctccg
    29881 cgatctgtta gtttaacatc tgtattttct aatccaagtg atgctgtact tggttttctt
    29941 ccagttgcag ccaaaacttt tgacgcttgg attgttactt cttggccatc ttctgtaaag
    30001 gtgacggcag ctgttgattc ttggtctgct acttgatcta cagatacacc tagatggaat
    30061 tcgattcccg catttgtcat gtcttctaaa atcatttgcg cgatatcttc atcttcacgt
    30121 ggaagaaatt cagaatgggc atcaagaacg acaactttag atccgtattc attgaacatt
    30181 gatgcaaatt ccaagccaat atatccagcc ccgatgatca ctaatttttc cggtaattgt
    30241 tcctgatcca tcgcttgcgt agaatcaatc aagtagcgac ttgtattcaa tcctttgatt
    30301 ggtaaaatga ttggttcaga accagtattg atgaaaatcc gttcgccttc aacaatcact
    30361 ttttcaccat tattcgtcac ttcgatttga tggttagaaa gaaaacgtgc tgtaccgtcc
    30421 atcactgtcc cagttgcctc atcgctgatc atatgataat ttttggcgcg aagcatgccc
    30481 gtcaattttt ctttccgagc aacagcctct gtaaagtcga ttcctctttc tccattgaaa
    30541 atcaatgatt tagaaggaat acagccgatg ttgatacatg ttccgccata catacgtgtt
    30601 gacttttcaa cgactaaaac cgattcacct tttgaagcta acgccttcgc taaagtctta
    30661 ccgccctttc caaaaccgat cacaatattt tgatattttt ccatcatttt tccctcgctt
    30721 cttttttacc taccgattgg tacaaaaata tgataaccga taattgtcta ttctccaaat
    30781 catctgcttt atttgtcaaa aaaaaccaga caaaaagcgg tcctttcacg tttttagtct
    30841 ggttcgattt cctttattct tctaaacaat cgttacttct acatcgatat ttcctctagt
    30901 tgctttggag taagggcaga attcatgcgc atcttctgca attttttggg cttcttcttc
    30961 gctgatgcca tcgatatgca cttctaatac tacaccgatc tgatagccgc catcatctaa
    31021 attataaaga gagacacgtg cttttactgt ggactctgct gtcattcctg cttctttgat
    31081 catatgttgt accgccccat tgaaacaaga agcataacct gctgcaaata attgttctgg
    31141 atttgttcct tctgcatgga ttcctggagg agtgattttc atatgcatcg agccatttgg
    31201 tgcctcgact tctccattgc gcccgccatg gttgatcatt gctgtttcgt atgctttttt
    31261 cattgtactg ctcctttcga ttgaccattt gctacttggc tataattata gtgtatgaca
    31321 agtaaggcgc tttctacaaa aattctgctt attcgaatac cagaatgccg tcttctacta
    31381 tttttccaaa aaacaaaaaa atactactcg tgaacaacag cgtcatattt gttccaaaat
    31441 aaatagcaat cttttctaca taatctttta tatgattgat tttaagatac atatatacca
    31501 gaaagttgac cccataaacc aatactgtta aaaaaataac catattcgtt accatttttt
    31561 cctccttttg ctggtctccc taccagcact cgatttaacc ataccacttt ttttgccgtc
    31621 caagcaacta gcctttcaaa aagactggtt tattctgctg ttaatgattc aagatcagaa
    31681 aaatgtccga ataattttgc taattttact aacgccaact tgttctttcc gaattcatca
    31741 ttttctatct gtaatactag taacggctca tgtaagctta aacggatcaa aaaccagccg
    31801 tttccgtatg gctcttctag atcatatcga ataccttctt cattttccgg gtcgaagttc
    31861 atcccttttt cttcttccaa cagtcgcttc atttcttcta atatcttgtt tccttgttcg
    31921 cgtggttcat cgctgaacaa ttttaatcgg atttcttgta cttctacggg ctgtttcaac
    31981 tctttgattt gttcatctaa tgtgatacct tttcttttta attctggcaa aagcatcagg
    32041 atctttgcga tgacatatgc accatcatcc agaaaatagt tttccttgaa tgcagcgtgt
    32101 ccgcttgttt cgatggctag ctgtgtatct ttcccaagac ggttaagttc taatgcttta
    32161 ttgattacat ttcgatagcc ggaaatataa cgaacttgga tgcctccttt ttcttcaatg
    32221 aatctttgta gatgagaaga agtaggggaa ttcgtcacga ttcttgttcc tggatgctct
    32281 tttaatacga ttgtacttaa tactgcgatc aaattatttc gattgatcac tgttccagaa
    32341 gcactgacaa ctgcagaacg atccacatct gtatcgaaaa tgatcccaag atctgcttca
    32401 tttgctaaaa cagcctgctt gatactttcc atcgcttctt tattatcagg atttgggata
    32461 tgattaggaa atcggccatc tggttccaaa aattgggaac ctgttgaatc cgcacctaag
    32521 ctattcaata ctttttcagc aaagaatcca ccagcaccat ttccggcatc aacaatgatt
    32581 ttccaaccat ttagtggttt gctttctagt gttccaatcc cctttttaat ttttgtgact
    32641 aaatcttgcg cataaggtgt caaaaggtct gctttttcta cgcttccagt ttgttcgctt
    32701 tttatttttt gctgctgtga taggataaaa gcaatatctt ctttttctgc tcctccttct
    32761 gaggtaaaga attttattcc attataataa tagggaagat ggctagcagt cagcataacc
    32821 gcagcatcgc acgagaactg ttcaaattga gtggacataa acatagcagg cgtagtagct
    32881 aattcgaaat cgatgacatg tatcccttgt tctttcagac tttggatcaa cgcctctttc
    32941 agtgctggtc cgcttatcct actgtcatga ccaatcccaa tcgtccattt tttatttgga
    33001 tcggttgatt tcttcttttt ctttatccag tttgctagtc cccagccgat cttttttacc
    33061 atgtctgtcg tcaagtttac ttcatatcct tcaactggta atgcgattcc tcgaatatcc
    33121 gatccatttt gcagcgcttt catatctttc atataaaagt cctcctcatt tattccctca
    33181 ttttttccag cttttctgca aatcgctgtg cttcttcttc tgagcggcaa ataataatga
    33241 atgtatctac accggccatc gttccgacaa cttcagggta agccacttca tctagccaat
    33301 tcgttaccac atcggcacca tttcgttcag tcaatacgat aaccatgaac tgaacagact
    33361 ggatacgcaa aacctcgcgt ctaattgctg tacgcaaacg ttcttcattt aaagaaacag
    33421 atggctggtt aaataatgta tagcgtacta ttttgttttc attttgactt tttactaact
    33481 tcatttctcg aatgtctcga gaaatcgttg cttgagtcac atcggcgcct gcttcatgca
    33541 gccgcgcaag cagctcttcc tgtgtcccaa taggttgttc tgtaatgatc tggcggatca
    33601 gtgcttgtcg ctgtttcttt ttcatattag acacctctca atgttgatta tagcaaaaga
    33661 taagtaatat ttcttcatat tttggtattt tttactttta ttttttgttt tcattcaggt
    33721 tgctaacctt tttctatttt aacacgcaaa atcgtcttca ttttttcagg tgctgatttt
    33781 cttggatcgc tgatgtaaat ctctttgtgt tctttagaag ctctttcata gccttctttt
    33841 gcgatgaatg cttctaattt ctcaaacgtt gctggttctt cggcataggg cccgacgtgt
    33901 aagatttggg cacaaagacc ttcttccatc tttttgaata ctacttgttc tttcaagtct
    33961 tccggaagtt tgctagaacg ctgaatggct tcttgtgcta tcgcttctgt aacaaagtca
    34021 ggctgtcgga tcatcaattg ataagaaaaa tgttcttttt tcatcactgg ttcatgcaaa
    34081 tacttttctt gcagtcccca ttgtccttcc agtggataga cagtatacat ctgataatca
    34141 ggaatcagcc aatttttttt aggcgacatg cgtattgcat agctgactgc atatagacag
    34201 gctactcttc gtttaaagtc ttcctgattc gggtcgccga tccctctgat gctaaagaat
    34261 gattttttag gaacctctag tatttgcggg ctttttttca tactatagct cttgtcttta
    34321 cgccattcaa ttttttccat ttttcttcct ccgcgaaatt ccatttagtt atttattatc
    34381 atacctcttt ttgagtgact tggctaatcg tgttgacact atttttcagt ttgtgctaga
    34441 ataagtgaag taaataaatc gtacagataa cacgtttcgg cgtgtcgaga gagaggcggt
    34501 ttctattttt ataatagaaa tcactctctt tttttacgaa attttttaga ggtgatgtaa
    34561 atgacaaaac aaaaacagct gcttttagta cctgcagtaa ttgcaacagg gatgatgtct
    34621 tttgcgggcg tattgatcga gacggccatg aatgtaactt tcccaactct tatcagacag
    34681 tttgatttaa cgactgcaca agtccaatgg gtaacaacga tttatctttt gatgatttcg
    34741 atcattgttc cgctgtctac ttatttgaat cgcaatttta gtctcaaaaa actcttttta
    34801 gcttcaaatc tgcttttctt ggcaggtata atgatcgatt tcttctctcc taccttcatg
    34861 gtcctattgt ttggtcgatt gctccaaggt gcagcgacag gtatcgctct tccgttgatg
    34921 ttccatatta tcttgacatt tgcccccctc aatcgacgag gcgcgatgat gggtgtcggt
    34981 actttgacaa cggccattgc tccagcaatt ggccccactt atggaggcat tatgacttca
    35041 cattttacat ggaatcatat cttcctgttt cttgtgcccg ttttgtttct ttctttgatt
    35101 atcggctggt ttgctattcc cgagatggca gtacaaaaaa gtggttattt ggattggata
    35161 agcgttttag gaatttgtct tttgtttagt ggaagtctaa catttttgag tacgttggga
    35221 acagtttcca gctggattgc tttaatcatc ggcggtattg gctggttcct tttttactat
    35281 cgaagtaaaa aagtggagca tccactgatc cgactgtcta ttctttcaaa taaaacattc
    35341 cgcttgtttt tgattggctt cttagtttat cagtttttat tacttggtgt atcttttgtc
    35401 ttgccgaatt tccttcagat cgttcaagga agtagtcctt ttgtcgctgg attagcgatg
    35461 cttcccggcg cagcggttgg tgctttgctt tctccttttt ccgggaaaat gctggatcaa
    35521 tatggtccga agaagccaat ttttgctggg ctgattcttt ctttgattgg ttggctagca
    35581 ttattcctac tcataggaca cgcttcagtg ggtgtattga ttgcttgtca tgtgttttat
    35641 atgatcggta tcggattatc ttacagcaat atgatgacca ccggaatgaa tgcactgaat
    35701 gaagaactac aaggagacgg gaacgcaatg ttcaatacct tgcagcagtt ttctggcgct
    35761 gtggctactt cattagtagc ggtcattatc aattacgtcc agcatcatac ttcccataac
    35821 tatgaagtgt ctactacatt aggatcaaaa gcagcattag gcgtcttgtt gctgttgctt
    35881 ctcgtaagct ttgctcgatt cgcctattat ctgttctttg ctaaaaaagc gtagattcca
    35941 tatacggcag gtgttgcatc tgccgttttt ttgtgtgaaa atggttgttt gtaaaaggag
    36001 gcttttttat ggaaaaaatt gccattatcg gtggcgggat cattggtatg accctagcca
    36061 gttacttaga tacatcaaaa ttcaatgttg ctttatttga tgaagggaca ggacaggcaa
    36121 ctaaagctag cgctgggatt atctcccctt ggttgtcgaa acgcagaaac aaacaatggt
    36181 atcgtctggc taaagacggc gctgcttttt tccctaaact tataaaagat ttccaacttg
    36241 atcaaacgat ttacgcacaa tcagggacac ttttgcttcg acctgaaaaa gatttagctg
    36301 aattggctgt tcttgccgag aaacgaaaag aagaagcgcc agaaattgga aacatcgaat
    36361 ggctttcacc tgaacagaca tctcaagcac ttccgttatt gaaaccagca gtttcactgc
    36421 gtatcagtgg tggtggtcgt ctggatggaa aagcatattt agaacatctt ggtcagcgtt
    36481 tagcacaaaa acaaatggag cagatccagg caaaagtcac tttgcataag aagagcgatt
    36541 cttggctcat caagggaccg tttggagaat acacagctga tcgtgtaatt ttgacacctg
    36601 gcccggcact taagccttta ttacaagaat taggctatgc tgcagatata cgtccgcaaa
    36661 aagggcagct cttagcattt cagacatctt ataagatgag tcaagactgg cctgttgcta
    36721 tgcttgacgg agaagctgat ttcattcctt tcatggatgg aaagatcctt ttaggtgcta
    36781 cccatgaaaa cgatcaaggc tgggatttgg ctcctactag cgaagcttat aagggattga
    36841 ctaagagtac agaacagttc ttgactgatc cagatcagat aaaaaactgg ccatacgagt
    36901 tccgtgtagg tacccgtgct tatacgtcag atttttcccc atttttcggc gtactgccag
    36961 atgatccaag cttactggct gctagcggtc taggctcttc tggcttgacc acaggtcctt
    37021 atatcggcta tctattagcc aacttcttaa atactggtca ttggcctacg gaagattatc
    37081 aaaaggacat ctccacctat attacgaaaa atccatcata gaaaaacagc tttttcaagt
    37141 aaggatcccg agcgatattg cgcatggatt acttcttgaa aaagctgtta ttttagttca
    37201 atttctgaat caaattctcc aaactttctt ttgcttcatc tggcaagaga tcttttccta
    37261 tctgagcttc aatgaatcgt aaacgaatat caagtcgttg tttcaccaga tttttatagg
    37321 acgtatcctc aaaagaaaca ggaaaatctg gtataggtaa atagtggatg tcttcaaatg
    37381 gaccaaacga cttgaattct gccgtttgtt gcacgattct ttcaacgatt gacaatgtcg
    37441 tttcaggttt gattttttta tcatcgaaat atccagtatt caggacatag caggctgttt
    37501 gctgtttcaa aaacaactct cgaaaagctt gatagtcttc cctaagagga tagacacgga
    37561 aaggattagc aaatggttca atgactagct catctagctg tctttttgta gtgatatttt
    37621 ccgcgtctga tcgttttgtt gctaatgttg caccaaaaga cgctgctaaa actgggtcat
    37681 tgatcttgat aattggcgga agcgaatcat ctttcatgat ccaaaaaaca gcatcgatct
    37741 tttcgctaag atgatcgact cggtcgggtg tcgcataacg tgatttgact gtccgcccat
    37801 ttccgtttcg tatatctcct gttactagga ctttttctcc tttacttgta catgtcacgc
    37861 ccacattctg acaagtaagg aaagaagaaa tggccggatc atcagacgga tagtcttgtg
    37921 ttttatcaaa gtaagaaggt tccaaggcag tagcaaaacc attttttcga gaaataacga
    37981 aagcatcgtc atgcaagatc gaaacagagt gaccttccgt atgttttgct aaggtaatcg
    38041 ttgattttcc agaaccggac aacccaaata cagccatcgt ataggtctgg tcattactag
    38101 catattgttt catcccaccg tggcaggcaa taaagccatt gcgatttccc aatgcccaag
    38161 caagcgtcaa agtcgctttt tttaattctc caaagtaacg taatcctagc acagccgctg
    38221 tattatggag agcatcaaac aaaatgagtc catttggaaa tgtttcatgt gtccattcgg
    38281 gatcacaaaa gatataaaga tctccctcat caaaggaaac agacttttga taagtctcta
    38341 agatcttcga attcgctggc tgaaaattca gcaaataaga atacaaattg ttctcaaatc
    38401 cttctggaat cagcaaatga ctttgcacag aaaattcttc agataggcca acgattactt
    38461 ttgtatggta aaactggcgc ttgcgacttt gatacacagc ttctcttaaa attttctcgt
    38521 atttgctttg ttccttgtct aagtcctcaa agatccgccg agcacttgct gttcttccca
    38581 caatgcttcc atcattgaat actagtgtcc taacatcagc tggtaaatct agttcttcag
    38641 catgtgagat tgttaaatct gtgatgatcg ttcctggact cccttttgct agttgataag
    38701 ctgtcttcct atcaaaaact tcatgaacat tattaccgta aaatgtcgtt tctacaatcg
    38761 atcgaatact ggataacagt ggatttccac ttgtgatttc gtttaattcg agactctctt
    38821 ttgtactcat ggctcctcct cattccctaa acaaaaaaac gttttcttta ttatacatta
    38881 ttcgagtttt tatttgtact gctgcgctgt gggaagcaaa cgagttattt ttcacacaaa
    38941 aaaaccgaga acttgaataa acaagtttct cggtttcatc attttccttt tatcggctta
    39001 gtaccagccg tttgctaacc agaatgtttt agcagcatcc catgaaccat aacgagatgt
    39061 tacatattgt tctgctacac gttcttgatt ggcagctgaa tagtcgccgt ttaagtatga
    39121 agcatctaat tgataacggc cgatgtaacg tccgttagta gctgtgtatg aaccgcctga
    39181 ttctttttgt gcgatccatt cttttgcaga gcttgaagtt ggcgctgttg cagcagctgg
    39241 ggcagcagga gctacttcaa ctgtttcaac aggtgcaacg tatgtatgtt cttgcgttgc
    39301 tgtttcagtt gtagatgctg tattttctgt tgttttgttt tctgttgttg ctgaagaatc
    39361 atttgaagtt gggattgtta attgttcacc aacataaatg cggttgatgt ttgcgatcga
    39421 atttttttca gcaattgcat cgatcattga gttgtctcct gcaaattttt gtgagatctt
    39481 agataatgaa tcacctgatt ttactgtata aacttcatca gcgtgagcat ttgtagttcc
    39541 tacaaacatt gcagtagcac cagcagcaaa agttgtacct aaaacaattt tcttaaatga
    39601 attcatatta aactcctttt tttctccgtt ttttattctt tc
//
LOCUS       DAFLWQ010000019        38239 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.020, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000019 DAFLWQ010000000
VERSION     DAFLWQ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38239
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.020"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(134..283)
                     /locus_tag="L1V16_000984"
     CDS             complement(134..283)
                     /locus_tag="L1V16_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275340.1"
                     /translation="MKKKVIPYCPKPRNAFERGLFKYFEGKKGQDHKEENQKKKSKKR
                     SEYIF"
     gene            1251..1577
                     /locus_tag="L1V16_000985"
     CDS             1251..1577
                     /locus_tag="L1V16_000985"
                     /inference="COORDINATES: protein motif:HMM:NF013698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1275341.1"
                     /translation="MFKIFRKNCCGLDVHKTWIYACIGITDANGRTVYKQARFSSFTK
                     GLNELAEWLAKYNCKDVCLESSGKFWIPVFNILEKTCFVTLAHPKYTKPQKGNKTDRK
                     DAKMDL"
     gene            1558..2493
                     /locus_tag="L1V16_000986"
     CDS             1558..2493
                     /locus_tag="L1V16_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBN1275342.1"
                     /translation="MQKWICDLFMCDMIKPSFIPGLEIRQLRDLMRYRTKLTNMKTSE
                     KNRALNCLTVSNLKLDDVFSDVFGKSSTSIIQYLLEHPGESFDVRPFIHARCKTPVEE
                     IQAAVEGAISVPQAIKLRQCLNHINEIEKHREEINLEIQALAEPFSPVLELLRTIPGL
                     DTQPITAIAILSEIGPDMSVFPTSKHFISWAGCCPRNDRSARRTKSTRISRAGQSLKP
                     LLVQIANALLRSKEHPEFKNRYRRIKANRGHKKAIIAICKMLLTAIWNVLSKVEPYSA
                     KGYLEPKPAKEEKVLTQSQALDLLRKRGYTIIDSA"
     gene            3122..3373
                     /locus_tag="L1V16_000987"
     CDS             3122..3373
                     /locus_tag="L1V16_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC ligand binding domain-containing
                     protein"
                     /protein_id="HBN1275343.1"
                     /translation="MKSNQKSGFYTFIKAISSVLECDCIIGPYSMLIKMGFPSTESLD
                     SFINDLSKFGRTNTQIVFSTLVSLMVYQFWNVYHALLLK"
     gene            3915..4073
                     /locus_tag="L1V16_000988"
     CDS             3915..4073
                     /locus_tag="L1V16_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1275344.1"
                     /translation="MNKKQACEFLGIDNNTLDKWIRVYNFPVIKIDGVVRFDVEDIKD
                     FMNTFKKN"
     gene            4145..5371
                     /locus_tag="L1V16_000989"
     CDS             4145..5371
                     /locus_tag="L1V16_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1275345.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGIASEKYQKVFPTRQLAIKA
                     EREMKKKIETVLREENANSLELKGKIKFKDFYESKWLPRYELGQTTRSNRAPSNVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILCYIEFNRTTKIIQCITAPKKMALEEKRIREGNQALSSEELTDWIEAVNNDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFNKNTVRLKYALDKYQRKTHTKGWKDTV
                     IQAPEVVMTLLREWKSAQAEQLLKLKIIQTPDQYLFTYSKPSGEVNCPVHADYLNYRI
                     NAIKKRHPELAQLSPHKLRHTYATIAREGGANMNQISNALTHSDISTTKIYVNTPDVV
                     DKSVFEAFQKGLNKCD"
     gene            complement(5460..5852)
                     /gene="rpsI"
                     /locus_tag="L1V16_000990"
     CDS             complement(5460..5852)
                     /gene="rpsI"
                     /locus_tag="L1V16_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBN1275346.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(5868..6311)
                     /gene="rplM"
                     /locus_tag="L1V16_000991"
     CDS             complement(5868..6311)
                     /gene="rplM"
                     /locus_tag="L1V16_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBN1275347.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(6830..7297)
                     /locus_tag="L1V16_000992"
     CDS             complement(6830..7297)
                     /locus_tag="L1V16_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBN1275348.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(7417..8955)
                     /locus_tag="L1V16_000993"
     CDS             complement(7417..8955)
                     /locus_tag="L1V16_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBN1275349.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            9035..9721
                     /locus_tag="L1V16_000994"
     CDS             9035..9721
                     /locus_tag="L1V16_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBN1275350.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(9922..10449)
                     /gene="msrA"
                     /locus_tag="L1V16_000995"
     CDS             complement(9922..10449)
                     /gene="msrA"
                     /locus_tag="L1V16_000995"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBN1275351.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(10533..11210)
                     /gene="pgmB"
                     /locus_tag="L1V16_000996"
     CDS             complement(10533..11210)
                     /gene="pgmB"
                     /locus_tag="L1V16_000996"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBN1275352.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(11207..12335)
                     /locus_tag="L1V16_000997"
                     /pseudo
     CDS             complement(11207..12335)
                     /locus_tag="L1V16_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(12335..14518)
                     /locus_tag="L1V16_000998"
     CDS             complement(12335..14518)
                     /locus_tag="L1V16_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBN1275353.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(14515..15540)
                     /locus_tag="L1V16_000999"
     CDS             complement(14515..15540)
                     /locus_tag="L1V16_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1275354.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTANRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(15585..16412)
                     /locus_tag="L1V16_001000"
     CDS             complement(15585..16412)
                     /locus_tag="L1V16_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBN1275355.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(16409..17476)
                     /locus_tag="L1V16_001001"
     CDS             complement(16409..17476)
                     /locus_tag="L1V16_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBN1275356.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(17502..18338)
                     /locus_tag="L1V16_001002"
     CDS             complement(17502..18338)
                     /locus_tag="L1V16_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1275357.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(18335..19204)
                     /locus_tag="L1V16_001003"
     CDS             complement(18335..19204)
                     /locus_tag="L1V16_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1275358.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(19274..20557)
                     /locus_tag="L1V16_001004"
     CDS             complement(19274..20557)
                     /locus_tag="L1V16_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBN1275359.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(20571..22256)
                     /locus_tag="L1V16_001005"
     CDS             complement(20571..22256)
                     /locus_tag="L1V16_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HBN1275360.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            22531..23556
                     /locus_tag="L1V16_001006"
     CDS             22531..23556
                     /locus_tag="L1V16_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1275361.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(24151..27825)
                     /gene="rpoC"
                     /locus_tag="L1V16_001007"
     CDS             complement(24151..27825)
                     /gene="rpoC"
                     /locus_tag="L1V16_001007"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBN1275362.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(27883..31500)
                     /gene="rpoB"
                     /locus_tag="L1V16_001008"
     CDS             complement(27883..31500)
                     /gene="rpoB"
                     /locus_tag="L1V16_001008"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBN1275363.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            32228..33196
                     /locus_tag="L1V16_001009"
     CDS             32228..33196
                     /locus_tag="L1V16_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1275364.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            33214..34119
                     /locus_tag="L1V16_001010"
     CDS             33214..34119
                     /locus_tag="L1V16_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1275365.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            34116..34922
                     /locus_tag="L1V16_001011"
     CDS             34116..34922
                     /locus_tag="L1V16_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1275366.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            35058..36047
                     /locus_tag="L1V16_001012"
     CDS             35058..36047
                     /locus_tag="L1V16_001012"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBN1275367.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMMTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(36364..36888)
                     /locus_tag="L1V16_001013"
     CDS             complement(36364..36888)
                     /locus_tag="L1V16_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HBN1275368.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            37175..>38239
                     /gene="scm"
                     /locus_tag="L1V16_001014"
     CDS             37175..>38239
                     /gene="scm"
                     /locus_tag="L1V16_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBN1275369.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        11028 a         8055 c         7105 g        12051 t
ORIGIN      
        1 atatgaatgt ttgtgaaaaa ataatacaac ttagtcattc tttacaacga tttatagaaa
       61 aacaacctct ttaaatataa aaggtacggg ttactgatta cttgtaaatc tttacgttcc
      121 agttttattc tttctaaaaa atatactcac ttcttttctt agacttcttt ttttgattct
      181 cctctttatg gtcttgtcct tttttgcctt caaaatattt aaataaaccc ctttcaaaag
      241 catttctagg ttttggacaa taaggaatga cttttttctt catataaata cctcatttaa
      301 ctatttgata tcatcacatt atcaaaaaaa ataggttttt tattaaaact atcttgacct
      361 ttcgggagat ttcactgtga tttattttta ttcccatact tttttcgttg gtcactttcg
      421 tatacctaat ctaagcgatc atcggcgacg gtgcttttac aacgaatggc aggacaaaac
      481 aaggggcgga aaaacttttt tgcctatttc ataaaaaact ttttcctaca gcaatccctt
      541 gttttgtcct accacacgtt gtgaacccaa agcacgccga cgaacgctta gctatacgaa
      601 aatgacctcc aaaaacaaaa aagtgaggtg aatagaaaca aaaagaaatt gaaatctccc
      661 aaaatgtcgt ccgcctcgga gacaacttgc tgctgaaaat ggttggttaa ttcatttaag
      721 tattaaataa gataaatcat caaattaatc ggaaaaatag catgattggc cttatcaaaa
      781 ataaactgta aaaacttata tttctatgag tggtggaaca atgctaatac caaattaatt
      841 tatcgattac ccacctgcac aaaccaaaga tagcattatt aggaaacgaa tcaatcagcg
      901 aatccagcat tataatgagg atactaaaaa taaagttttc ataattataa atccgccttc
      961 ctacgaaagg caccaatgag gtgatgaaaa ccttagagcg ctttctttct ttttttattc
     1021 cgtgttaccc tttccttgca ggtccctggt acactacaga acccgaggag gtgagtggcg
     1081 gggctgtata gcggcaaccc cgcataatta tatggtgtcg gtcatccgtt aaggcatcaa
     1141 tgaatggcgc aaacccgtag cccgtaaact tatctcttcc gaagttgact cgatttcgcc
     1201 ggatgaccag tccctaccaa acctgtacta tttttttaca ggaggttgct atgttcaaaa
     1261 tctttcgtaa aaattgttgt ggcttggatg tccacaaaac gtggatctat gcgtgtatcg
     1321 gaatcacaga tgcgaatggt cgtacagtgt ataagcaagc tcgcttctct tcctttacaa
     1381 aaggtctcaa tgaattagct gaatggcttg ctaaatacaa ctgtaaggat gtgtgtttgg
     1441 aatcttccgg taaattttgg attcctgttt ttaatattct tgaaaaaact tgttttgtca
     1501 cactggctca tccgaagtac accaaacccc agaaaggaaa taaaacagat cgcaaagatg
     1561 caaaaatgga tttgtgatct ctttatgtgc gacatgatca aacccagttt tattcctggt
     1621 cttgaaatcc gccagcttcg tgatctaatg cgttatcgga cgaaactgac caacatgaaa
     1681 acaagtgaaa agaatcgtgc tttaaactgc ttaaccgttt ctaatctgaa actagatgat
     1741 gtttttagtg atgtgttcgg aaaatcatcc acttctatca tccaatactt gttagaacat
     1801 cccggtgaat catttgatgt tcgaccattt atccatgccc gttgtaaaac tcccgttgaa
     1861 gaaatccaag cggcagttga gggggcgatt tctgtacctc aagcgattaa gcttcgccaa
     1921 tgcctcaacc atattaacga gattgagaag catcgagaag agatcaatct agagattcaa
     1981 gctcttgcag aacccttctc ccctgttttg gaactacttc gtaccatacc gggcttagac
     2041 actcagccaa taacagcgat tgcgattctt tcagaaatag gaccggatat gtccgtgttt
     2101 ccaacttcga aacactttat ttcttgggct ggatgctgtc caagaaacga tcgcagtgcc
     2161 cgacgaacaa aatcaacacg tatctctcgt gcagggcagt cgttgaaacc gctacttgta
     2221 cagattgcca atgctcttct cagatccaaa gaacatccag aatttaaaaa tcgctatcgt
     2281 agaatcaaag cgaatcgtgg acacaagaaa gctatcattg ctatttgtaa gatgctcctg
     2341 accgctatct ggaatgtctt atcaaaggtg gaaccctatt ctgctaaagg atatctggag
     2401 ccaaaacctg cgaaagaaga gaaagttctg acgcaatccc aagctctgga ccttttaaga
     2461 aaacgcggat ataccattat agatagtgct taaaccaaag ttacgttgat tcttcctaaa
     2521 tagactcgtt gtcttccatt tcaaaaattt tgaaaacggt aggcttattt agtgtaccgt
     2581 tcttcaggta tcttcaaata gatttatttt caaacttatt tcctttcttc ttttactctc
     2641 ctatagctta gcatttaagt gggcactcgt gtcaccttgc tagatagcta tgaatgccgt
     2701 aataagcctc ctagtatata ggcagactgc caattataac tgattcaatc cacattatga
     2761 taaaatccac cttttcgttt catatgtgtt gaaatatcac atatgtcaaa agtgcacgag
     2821 tcttttcatt cagtgctttg taaatactca aaattattcc ttttcacttt aaaaaaaaga
     2881 taattagtac aaaatcagaa atgaggaaag tattaggatg gactagaaag gagttgttga
     2941 atttgttgca acagattggt catttatcaa ttaaaaatta ggtgaagttt tattcatcac
     3001 tgcagctgct gtttcccaga gaataaaacg tctagaagaa actggtcagt tactgtatta
     3061 tcaagcagca attgactacg aacaagcttg attactaacc aaagcgttta tccacctgtt
     3121 gattaaatca aatcaaaaat caggttttta tacgttcata aaagcaatct ccagtgtact
     3181 cgaatgtgac tgtatcatag gtccttattc gatgttaatc aaaatggggt ttccttctac
     3241 cgaatcattg gacagtttta tcaatgattt atcaaagttt ggacgaacca acacccaaat
     3301 cgttttctcg actcttgttt ccttaatggt ttatcagttc tggaatgttt atcatgcgct
     3361 tttattaaaa tagaaaagag cttttttcat gcgacaaagc agtgatcatt tattggcaca
     3421 tgcaatcttt gtggatccat tttttgaaaa tacgatattt agttttgacc caaaaatctt
     3481 taaatacgta tttgataatt tatcttaaca accagataat tttattcagc accgtattat
     3541 ctatattgaa ttctcggaat caagataaat ttttttccgt ttttgtttct tttttaatct
     3601 tcttcttgtt attaatagtg attaggatga tattcctata ttgatctttg ataattagat
     3661 ataatttttg aataacgttc cctgctattc gagctagaaa tacaagtacg ccatgaccta
     3721 gttagcgaca actacttaga gatttctttt gttctgggac aacaaaatgc catgacaata
     3781 gcagtaaata atgatacttc cgtaaggctc gccgtaaact ggggagaggt gaaattccta
     3841 tgtgcttacc caaagcggtt caaaaatttt aaactattat tttaggagat gattttataa
     3901 aatcgaaagc ctacttgaat aaaaaacaag cctgtgaatt tctaggaatt gataataata
     3961 ctttagataa gtggattcgt gtatataatt ttccagtaat aaaaattgat ggcgtagttc
     4021 gctttgacgt agaggatatc aaagatttca tgaatacatt caaaaaaaat tgaaattttc
     4081 ttctcgtcac atatactata aatagcgaaa tgtactgcct tactttttaa aggagtgagg
     4141 aagtttgcct acaaagcttt caaatgggaa atataaaact aatctgaggt atccaaaaaa
     4201 attcagagaa atcactggaa ttgcatcaga gaagtatcaa aaagtatttc caactaggca
     4261 attagctatt aaggccgaaa gggaaatgaa aaagaagatt gaaacagttt taagagagga
     4321 gaatgcaaac tcactagaat tgaaaggaaa aataaaattt aaagattttt atgaatcaaa
     4381 atggcttcct agatatgaac taggtcaaac tactaggtca aacagggctc caagtaatgt
     4441 aacaattagt aatactaagg atatattccg attgcacatc cttccaatgt ttggtgaata
     4501 tgcaatgaat tatctgaatt caaatactga gataatatca gatgaattaa caaagaaatc
     4561 gaaagaatac gcaaatataa aaattatcaa aggctatgtt cgctctatgt ttgatattgc
     4621 cgaaatacta tgttatatcg aattcaaccg aactaccaaa attattcaat gtattaccgc
     4681 gcctaagaaa atggctttag aagaaaaaag gataagggaa gggaatcaag cattatcatc
     4741 agaagagctg actgattgga tagaagcagt aaacaatgac ttaaataatc acttgcttac
     4801 acttcacgat tacacacttt tcatgcttac cttatatcta ggtgatagaa aaagtgagac
     4861 ttatgctctg caatggaaat atattgattt taataaaaat acggttcgtc tcaaatatgc
     4921 tttagataaa tatcaaagaa agacacatac aaaaggttgg aaagacaccg ttattcaggc
     4981 accagaagtt gtgatgacat tattaagaga atggaaatca gctcaggctg aacaattgtt
     5041 gaaactaaaa attatacaaa cacctgacca gtacctcttt acctattcca aaccttctgg
     5101 agaagtaaat tgtcctgttc acgctgacta cttaaactat cgaatcaatg caataaaaaa
     5161 aaggcatcct gaattggctc aattatctcc acacaaactt cgtcatacct atgcaactat
     5221 agctagggaa ggtggagcaa atatgaatca aatctctaat gctttaacgc actcggatat
     5281 ttctactaca aaaatatacg tgaacacacc tgacgtagtt gataaatctg tttttgaagc
     5341 atttcaaaaa ggattgaata agtgtgatta acatgtgttc tcaaatgtgt tcttattata
     5401 aaaaaagaca ctttccaaat aattgaaaag tgtcctgaaa tattgatata aaaagaatat
     5461 taacgttttg agaattgtga agctttacga gcttttttaa gacctggttt tttacgttcg
     5521 accatacgtg cgtcacgagt aagtaagcca gcacgtttaa gagctaaacg gaagtcagga
     5581 tcaacttcta gcaatgcacg agcgatacca tgacggatag ctcctgattg tccagcgtat
     5641 cctccgccgt ttacgttaac aaatacgtca tatgcgcctt ttgtttcagt aacagcgaaa
     5701 ggttgattga ttacttcacg caagtcagca tgtggaatgt attcttcaac atctttttta
     5761 tttacagtaa ttttgccagt tcctggtact agacgtacgc gagcaactgc gtttttacga
     5821 cggcctgtgc cgatatattg aacttgtgcc aatgaaattc cctcctatta gattaagttt
     5881 gtgatgtcta aaacttctgg ttgttgtgct gcatgtggat gttctgctcc accgtatacg
     5941 ttcaattttg taaattgttt gcggcctaaa gtgtttttag gaagcatacc ttttacagaa
     6001 gtttcgatca aacgacgaga atttttagca cgcaattcgc cagcagtgat tgatttcaat
     6061 cctcctgggt agttgctgtg acggtaataa attttgtcag tcgctttttt acctgttaat
     6121 ttcactttgt ctgcattgat gacgatgacg aaatcgccag tatccaaatg aggtgtgaaa
     6181 gttggtttat ttttaccacg tagtacagat gcaacaactg ttgaaagacg tcccaatgga
     6241 acatcagttg cgtctactac ataccattta cgttctactt cgcctggttt ggccatatat
     6301 gttgtacgca cgttattttc ctccaattta agttctgatg tttgacatac acttcgagtt
     6361 tccggggctc tttgtggggc aaacaatacc atttaacata ttacccgcta atctagtcaa
     6421 tgtcaacgtt tttctgcttg attgaaaaat ttatatgaaa ctttacttct tttctttctt
     6481 ttatataaaa gggtcgtttc ctgtcaaaat gaaaaacaaa aagaggctgt gacaaaagtc
     6541 ttgtcacaac cccttatttt gaataaacgg tgttctcctg ccaactcctc ggtcacaagt
     6601 cacaatatcc ataaaacata agaagctgtt ttttaaaatt gtttcttgtg actcggagct
     6661 gaacggcagg cttacaacct cttggtaaac ggtgttcaat cagctgaccc tcggtattag
     6721 ctcaaaaaac ggcaaaatat gaggaactat tttgacgttt gtttctctaa tactcaggtc
     6781 aaaacgctga tttcacaacc tctttttcgg tcaagttcaa caacagtttt tacgcgtcga
     6841 tctctggcgc tttgcccaaa tgagcttgga tcatccagat acgtttttct gtggctgttt
     6901 tgaattcgat aaagatatct tgtgttggat cgtcgccttc ttctccagaa acttcgattc
     6961 ctttttggta aagatctgct agataacgat agcctgcaac aagtgtttcc aaacgttctg
     7021 gaatagtacg atcccagcgg ccaatttcat cagggatttt tgtgttatct gcaaattcac
     7081 gcaatgtaga ataaggtgaa ccgtctaatg tgatcaagcg ttcggatact tcatctaact
     7141 gagcgttcaa atcatccatg aactcatcca tcattgggtg caatgtaagg aaacctggtc
     7201 ctctcatgta ccaatgtgtt tggtgaacaa caacagacat ttggcttaga tctgcaacta
     7261 attgatttaa tacttctttg gtttgttgga atttcatctt tcttgcctcc taacattttc
     7321 ttacacttaa aataatagta gactttcaat gaaaagtaca acaaaatcat ttacctgaga
     7381 acgattttca gttcgctttt ttatccgtaa agccaatcat ttttcagaat cagctaattc
     7441 ttctcgcagt tgagcaaatt gctgataagt ctgtgctaaa tgcttttgtg tcgaaacaaa
     7501 taatggatag attttctgat attttttatg atcagtttct tgtactccaa cttgctcttt
     7561 caattctatc aattcctgtg cttcactgat actttggatc tttccgatgc ttctccagcc
     7621 taaaatcaca gctcctaatg cggatgcttc tgtgacagta gggaaaacaa gcgggtaacc
     7681 cagtacatca gccatcatct gacgaaaaat cggagattga gcaaacccgc ctgtagcacg
     7741 gatctctgtg agctgatttt cctggcaaac tccttttaaa atccgataaa ggttgagaca
     7801 gatcccttct agaatcgcct tcatcatttc tttttctgta tgttgccgct gtaaaccgat
     7861 aaaactgcca aacgcatctg cgtcccaaag cggtgctcgc tcaccaagta aatagggatg
     7921 aaaaatcaga ccattggcac ccgctggcac aaaagcgata gccgaaagca gtgcatcata
     7981 tggattttct cctttttctt tagcagattg aacgacttcc tgtaaaaatg tatgccctgc
     8041 ccaatcaaag atgccagcac cattgctagt cgctcctccc actacccaat gtttctgatc
     8101 cagaacataa caaaacgtct ccatttctgg atggaactga ggctgagtag taataaaacg
     8161 aagtgctccg ctcgttccta cggtcaaagc ggcgatcgta tcaccaaaag cacctaaccc
     8221 tagattagaa agcggcccgt ctgcccctcc caaaacaaat gatatatcat ttggcaaacc
     8281 tagttctgct gctgtttttg atggtagacc tgttacttga taggtggaag gaaagacttg
     8341 cggcaattgc tctattcgaa tgttcaagta gtcaagcact tcttctgccc attggaattc
     8401 atggatatca aaatatccag ttcctgaagc tgttccgtag tcgctgatca gttcgccaaa
     8461 caatctataa aagatatagt ctttgatacc gacaaaataa gcagtttttt tgaataattc
     8521 aggttggctg ttttgcagcc acttgatttt gttcaatggt gtcattggat gaatcggcgt
     8581 cccagtctgc cgataaaatt ctttgccaag cacggtatat ttcagttttt ctgcttcgtc
     8641 cgctgctcgg ttatctgccc aagtgatcat tcgagataac ggtgttttct cttcatccaa
     8701 caatatcagg ccatgcatcg cagaggagaa ggagacaaat tgaatgattg tgtctgaagg
     8761 caactgttta attacttctt ttataacggt gcagacacct tgaaagatca attcctgatc
     8821 ttgttctgcc atcccttgtg tttcttggat caaagggtag cgaaaataag cggatgctgc
     8881 ttcttgggct tcatctgtga aagcaactgc tttggtttgt gtggttccga tatctaatcc
     8941 gattgaaacg ttcatttttt cacctcaaat tttatgtatg tacaaaaatt tagtttaagc
     9001 ttgcgtatct tggttttgaa aagggggaga tggcgtgtta ctttatttta tcattggttg
     9061 ctgtatcgga tcatttttat gtttaaccgc ccagcggatt ccgttaggtc actctattat
     9121 ttatcctaga tctcattgtg tcaaatgctg tcgttcgctt tcttggtatg aattgattcc
     9181 gattctctcg atcatcgtcc aacgatttcg ctgccgctat tgcaggtgtc ggttgccctt
     9241 ctactatttg ttggcagaag ccttatgtgg tggtcttttt gcctggttct ttactttttc
     9301 ttccgcaaga aatttttcga cgttcatatg gatgctttcg gctttgctat tttcgttgat
     9361 ggatttattt tacttcatgg tccattctca cacgctattc tgttcttggg caattttatg
     9421 gattttttgg ttgcaggccg gcgtcttcca atggcaaagt gtgctgttaa cgtttatcgt
     9481 aggcggtgtg tgccttcgct atggtcaatc ctatctcgga gctggcgata ctctgttgat
     9541 gctttcttgg agtggtggct tgtctctaga agagttgctt cagatcttgt ttcttgctag
     9601 tctgtttgga atatccgttt tttctgttta ctttatctgt cataaaaaaa agttggaaaa
     9661 gctgcctttc attccttttt tgagcagtgc gttgctgatt gtccttcatc ttaggtattg
     9721 aaaaaaggtt gtgacaaacg acttgtcaca acctctgata tatagtgttc tcttaccaaa
     9781 tccttgtgac ttggagctag gcgacaggtt cacaacctct ccactaaatg gtgttcaatc
     9841 agctgaccct cagtattagc tcaaaatgct ggttttacaa cctctgatat acggtgttcc
     9901 ataagtagct ttttcggctt cttatttctt gacgccccaa tgtcgacgaa ggaaacctgc
     9961 acgtccagaa ccttctcgat aaagattgta atggagcttg tttttcttgt aataatcctg
    10021 atggtaatct tctgcaggat aaaattcgct tcttggttcg atttttgtca cgattggctt
    10081 atcgaatcgc ccgctgtctt gcaatgcttg ttttgaacgc tctgcaatat ttcgttcttc
    10141 ttcatcatta tagtagatca ctggacgata agaatcaccg cgatcagcga actgtcctaa
    10201 tgcgtcagtc ggatcggttt gctgccaata gatttccacc aactgatcat aagaaataac
    10261 ttctggatca tattcgatct ctactgcttc tgtatgccct gttgtgcctg ttgttacttg
    10321 ttcataagtt ggatttggta catgcccgcc agtataaccg gatgtcacag aaatgatccc
    10381 tggctgctct tcaaatggtt tgaccataca ccaaaagcat ccgcctgcga aaactgcttt
    10441 ttttgtcata taaaatcccc cttttttctc atcatacctt gatttccaaa aggaggataa
    10501 cgttttgctt gtgacagaaa aaacggaaac tattatatac gtgatacggc ttctgataaa
    10561 tgccaaaacg aacgtacttg atcaaaaacg gttaaatcag gaatcacata ttcagcagaa
    10621 ggaagattta tgttttcacc tattcccaat acatgcatgt taccagccaa agctgcttga
    10681 caaccagctt ctgaatcttc aatgaccaag catgcatttg gcggtacatt caattgctgt
    10741 gctcctttga gaaaaacttc tggatcaggt tttgcttttg atacttgcgt gccgtcaata
    10801 aggacatcaa aataacttgt caaattcgtt ttttctaaaa tgaggcgtgc atttttgctt
    10861 gctgatccca atccgatctt gatgtttgtt tttttcaagt actcaagaac agctattgca
    10921 ccaggcaaaa cggatgtttc atccattttt tgaatcgctt gaagatatag attgtttttt
    10981 tgctcagcaa aggctgattt ctctttttct gagaatttct gttccatttt tccaaatgac
    11041 agcaatcgct ctagtgactc ggttctggat attcctttca gttgctcgtt ttctttctca
    11101 gtgaatggaa tggacagctg gttagctaaa accagccacg cttcgtaatg ataacgagct
    11161 gtgtctacaa gaacgccatc taaatcgaat agtgctgctt tgattttcat cgattacctc
    11221 cttgaaaatg aacgacttga agtaaagatg cgatgttttt agctgtgcga tgaagattat
    11281 cagtggcttg ctgtaaagct tcttgtaaag gcacagctgc aggaaggatc ggaaaaacgg
    11341 ccgaaatgcc aacatctgct gctttttcgc ttcctttacc aacacttccg caaatagcta
    11401 tcacaggaac gccctctggt actcttctag caatcccaac tggcgctttt ccttttagac
    11461 tttgtccatc tagacgtcct tcgcctacga ttacgaggtc tgcttgctgt acccgtatcg
    11521 aactccagta aatccaatac gtagtcgatg ccagagacta ttttccctga agcaaatgct
    11581 aacagtcctg cacccattcc accaccagca ctactgcccg atgcctcgat tacttgaggg
    11641 gcaaatctca tataaaaatc atgcatggct tggtcagcca ctgctaattc attttctttc
    11701 aagccttttt gtggtccgaa aacaaaagaa gcgccttctt ttccgcataa aagattagta
    11761 acatcagtaa tgacagtgat tttggcttta atcagctcaa taggcacgtt cgttttatca
    11821 actgtagcaa ttttacctag attttctccc agtgcttcta ctttttgatt atcttgatcg
    11881 taaaaagcat aacctagacc ttctgccatg ccgatgccgc catcgttggt actacttccg
    11941 ccaacgccga tgatgatgtg tcgaacacct tgttgcaaca attgtcgtat cagttctcct
    12001 actcctcgcg tggataacct aagtggctgt tgttggttta gtgggacatc tttcaatccg
    12061 acgatttctg ccatttcaaa aatcgcagtt tgaccgtctg aagcgtactg gatttctttg
    12121 tttttgccaa atgcattagt aacgactgct gtttgccgct tcaaccttaa actgtctgct
    12181 aatgatgaaa ccgttccttc tcctccatcg cctataggta gcagatcata ttcagcctga
    12241 acaaaaactt cttgaaaacc tgattgaatg gcttgtgctg cctctaaggc tgtcagactt
    12301 tctttgaaag aatctggcgc aatcagaata cgcattattt tcccctccgt tccaagatca
    12361 gttctttttc cagctggtat tggtctccat tgacaaaaat aggtaatgtt tctttcgtct
    12421 ctttttttat tactatttgt ttttttgtca aaacaaatag caacctgtga tttttccaaa
    12481 taaaaggaaa agaaattttt tcccatgctg aaggaagtct tggagaaata gaaagagttc
    12541 cattcgttac tgtaatacct gaaaaaccaa atataactgc tagccatagt gctcctaatg
    12601 aagcagcatg aattccgtca tctgatgaat gcggatctgg tcctaaatca atcaggcacg
    12661 cttcttggaa taaatgatac gcccattcca tttcttggat acggcaagcc tctatggcgt
    12721 gaatcgcttt actcaacgat gagtcgtgga ttgttttgtt ttcatagtaa tgcaaattct
    12781 tagaaacgat tggttgagaa aaatactcag gtaataagta taacagcatg acaagatctg
    12841 cttgcttgct gacttggagt tcatttactt cgctacgggc ataatcaagt aaaatagact
    12901 ggctgccagg acgttctttg taagtggtca aatcaataac tggcttactg agatacgtgt
    12961 catcttgcgg aatcagctgt tctttgttag gcactggcaa atataactta tctaaaaaat
    13021 tttgacattc tttcaaaaaa agcggatcgc cagcttgata tttaacagct aaggccacat
    13081 tataatgcgc cagatagttc gtatatgcat tattgtcgat atattctgtg tattcatctg
    13141 gaccaatgac tctgtgtatc tctaaatgat catcgacttt tacagctctg ctcagccaaa
    13201 aagctgctgt ttcatgaatg agcgtttttc cctttgtttc taaaaacgat tgatcctctg
    13261 ttgcttggac atactcttga acggcataag caaggtctgc actgatatga tgttctgcgg
    13321 cagctgaagc aacttcttgt cttgttccgg ttttgatatt caatgcagca aatttgggtg
    13381 tctcttcctg accagtgtgt gcgctttccc atgggaaaag tgcaccttga tagtgataat
    13441 ctcttgcttt ttgccgtgcg ccttctaatc gatcataacg gtacagcagc aaattctttg
    13501 ctacttcagg aaactgatat aaaaagaaag gcaggataaa aatttccgta tcccagaaaa
    13561 catgcccttt ataaccttcg ccagttagtc ccttcgcccc tacactaaca cttggatcat
    13621 tgcggggagt cataatctgt aaatggtaag cagcgaagtc catcgctaac tgatcgaaag
    13681 aagaatcgcc ttggatcgtt atccgatgct gatgccaaaa atctgtccaa taagacatcg
    13741 actgctctaa aatttctgta taactaacgc ttttctgggc ttgggcaata cttttcttaa
    13801 acgggtctgt ttgctgaaga gaggtagaga gcacgatgat cttctccagc gtaaaggacg
    13861 tattttttct gatcttttct gaaaaggaag cggtgatccg gcgatttttt gcttggaata
    13921 cacctgcttt attgaattta gctgcaatcc caatatcaat tttactttct gttgtctggt
    13981 aggatgcact gatcaaatcg tcaccaaata ctcgcagttc tttttcaacc aactgctgtg
    14041 taccaaaatt ggtttgctgt ccatcgatac ccgttttcac atctacttgg cagtcttcgg
    14101 tcaacggctt gatgaccact ttcagggctg cctgatggag attattttga tcagcaacac
    14161 gacaagtaat gacttccact ttttttcctt gagcagtttc aatgagcgca tagcgtttaa
    14221 gctctcccat ttctaaatct agtgcccgct cgtatgcaag aactttcatc gtctcaagag
    14281 aaaaatgttc accgtcgatt tttatttccc atctgatgac atctgggaga ttcactaact
    14341 cggctgattc tgctcctaaa ggtcggttat atacaccagc tgcaaacatt ccccttactt
    14401 gattccgata gtcttcctcc tggcttcctc tgataccaaa aaatccattt ccaatggtca
    14461 tctgactcgc atacttattg atatactcta aatcaaactg tttttcttct actttcataa
    14521 ggtaataact tctcctgttt ctgccgaacg atataaattt tccaccagat tctggatgac
    14581 atatccttgc cagccatctg caatcatctg agtctggtca ccgagcgccc gattcacaaa
    14641 atgagccata cttagttcat gtgggtcatt aactggcgtg gtcttttgta aggaaaccag
    14701 ctttccatct acatcttcga atagttcgcc tggatacaga ttagcacctg cctgatcgcc
    14761 acaaaaagcc acattcagtt tgtcttctct gatattcaaa gcaaacgaag tattcagttg
    14821 gatgatcttg ccgttttcta attccagtgt gccaaaaatt gcatcttcta ctgtgaattt
    14881 gcttggatcc catttcccga atttccctga attttttttc gtaccaattt tttggaagct
    14941 gtacgcccga acgcttttta ctttaggaaa tccagtaata tacatcgctg tatcaagcat
    15001 gtgaatgcca taatcgatca aaggcccgcc tccttgaagt tctttgtcga taaacgttcc
    15061 ccagcctgga acaccagacc gacgaagcgc attcgcttct acgtaataaa tatccccgag
    15121 aacatcaaga tgattcttga tcattgttgc ttcgtcagaa aaacgatgct ggaatccata
    15181 agccaaaatc tgcccgtttt tatcggctgt ctctgccatc tttcttgctt gatcagctgt
    15241 catagctggt ggtttctcgc acatcactga agcattagct tcgagggcag ccaatacatg
    15301 ttcgaagtga aagcgattgg ctgtacagac actcacgata tcgggagaaa tctcattcag
    15361 catttgtgta actgatgtat acgcatgaga aaatcctgta cgtcggcaaa agtcttctgc
    15421 tcgctggctg actggatcaa ccacagcggc caattctaag acatctgatc ttttttgata
    15481 ataagcagca tgtacttttt ctgctacttg tccagcgcct atgattgcta ctttcttcat
    15541 ttatttctct ctcctttgct tatttactta ttgttattct ttctctattc tttctctaaa
    15601 tcatttaaat gacgcgctgt ttccagacag tttttcaagt attgcaatga ttcctgataa
    15661 attttcactt cattttctcc tcgcaaacga cattcatata ccatataacc ttcatactca
    15721 ttttgaagta gcgtttgaaa atggcgagta aaatcaattg cgccagatcc tggttggtag
    15781 cgatgattat ctgctaaatg gatatgaccc acatactctt tttgcgtagt caatgctttt
    15841 gaaatatcat cttcttcaat attcatatga taaaaatcag cgatgatctg cacatgtttc
    15901 aattgattag agtcaatgta atgacgcgca tccgctaaca aattgatcat atggtcttgg
    15961 tatcggttca aaggctccaa ataaataacc gtacctgttt cttcggctac tttatctaaa
    16021 taacgaagtg attcgctgac tgctttatag tctccttctt tgcttcgggg tgaaaccatc
    16081 ggcggtaatc gataagtgaa cattccccaa gctgctggga taacgattcc tttgcctcca
    16141 acctcgctta gtgcacgcaa aatctcagca atttgacgta caccattaag acgccgttct
    16201 tcgataaagt caccgatcca cccatcgtag ccgttacaag ctgtcactac tgggatccct
    16261 gtttctttga ttgcctgttt gactgtgtcg atattttcta ttaacaactt accgtcgatt
    16321 tcgtattctt caaatccaca gtctttgata aatctaaatt tttctaaaat gtctcttggg
    16381 aaaaatgctt gatcttgcgt accgaatttc attgttctcc tcctcggact tgaacgccca
    16441 ttttgatact ttcttctggg tgctggtcta cataacgcat gtaagcttct gcgctttctg
    16501 caaatggcac aactggatca atgatttctt cacaatccaa gtaaccgttc atcaataatt
    16561 cccaacatgt gtcctcgatt cgtttacggt tccatcttgg gtaatctggg tttggttcac
    16621 tagatgctcg agcaaagacg atttttgcat tattgaaatg tgcttcgcga ccaagattaa
    16681 acccagctgg aaaaggttta gcaaaggcaa cataagaaat gatcccgcca tagccgatcc
    16741 ctcttaaaga agcttgtaat gcggcagcac tgccactcgt ttcaataact gaatctactc
    16801 cacgtttatc tgtcaattcc tttagacgaa aaccgacatc tgctttcata ggatctagcg
    16861 tgtaatcggc accgtatttt tctgctaatt ctctacgctg cgctatggga tcgatcccaa
    16921 cgatggtagt agcacctgct tttttagcta attgaatcgc aatttgcccg atagcgccta
    16981 aaccgaagat tgctacagca tcacctgctc gaacatgtgc ttcccggata ccacctaaag
    17041 cgaattgagc aggatcgtaa catactgcat ttttccattg atccaaccga tcaagtttac
    17101 gtagtttata attatcaaca ccgtttgtaa tcagcgtttc acgaatgggt ccataagtgc
    17161 agactaactc tcctttttga tactctgtca ccaaactgcc cgtttcttcg atcgtaccga
    17221 caatcatatt tcctaattga aattcgccaa ataccacacc gcgttggctt ccttcttctc
    17281 ttggcaagaa taggcgccat tcttctgaaa attcttcatc gataaatgga cttaatcctc
    17341 taaagtcgac aatttctgtt cctggttttg gagtagcgaa aattactcgg atacgtactt
    17401 cgttcttttc gatctcacgg tcttcgtaat ctttgaatcc ggctattctt ggttctaatg
    17461 caactaattt tttcatcttt tctttcctct ttcttttctt tttatccttt tacgccgcct
    17521 tcgactaaat cacctttaat aaatcgttca gataacgcat acataatgat gactggtaaa
    17581 gcggtcacca atgaagcggc catcattcgt ccccaaatgt agtctggtgt actgaataat
    17641 gtgttcaaac cgattggtaa agtaaatttt tcggaggtcg acaggaaaat cgaagcaaat
    17701 aaataatcat tccacgaaac cataaagcaa taaacgaaga cagaaatgat tccagaaata
    17761 gccaatggta taatgatccg aataatgatc tggatccggc taagaccatc gatcattgct
    17821 gcttcttcaa tatcagtcgg aatcgtgtca aaataacttt ttagcatgaa tatcgcagta
    17881 ggaagtgttt gaacgaccat cgtgataatc agtgctgtat tggtatcata caaacctaga
    17941 ccggaaatga ttttaaataa tggaacaacg atcaaaatac cggaaaacat ataaacggtg
    18001 taaaagctag cattgatttt cgagcgagct ttgaagcgta gttttgacaa agcgtatgcc
    18061 ccgctgatcc caatcactac tgcagttacg gaggctatca aggagatcac taaactattt
    18121 ttgaaataca tgatgaatgg aaaaatctca gcattgaaaa tatcctgata atgttcaaaa
    18181 gtccattctt tcggaaaaat agtttgtgtc gttgcaattg cttcttgtga atccttgaat
    18241 gatgtcatca gcatgatcaa aaatggaaac aaattgacag ctaatagcaa caaaatcgtc
    18301 gcgtaaaata agattttcct gctcttttta tttttcattt caagtccacc ttctttcgtg
    18361 agagcaagac gaccgctgca ataatgatga acaatagaat cgatatagct gctgcttttc
    18421 caagatcatt gaacgcaaag gctgtctgat acaaataaac gcctaagata ttgactttat
    18481 tcgtcagtag atagacatct gtaaacatat agaacatcca gatagatcgt aaaacaatca
    18541 cagttgctag tactggtttg attgccggca gtgtcacgat cttgaacttc tgccaagcat
    18601 ttgcaccgtc catttcagct gcttcataaa gcgttttgtc gactgtttgc aaaatagcca
    18661 aaaatgaaat aaacgcatac ggatagtatc tccagatagc aaacaaaacg accataaaga
    18721 agctagcaac tggctggtcg aaccacagcg gtgcttcgtt gaaaagctgc aacctatcta
    18781 ctaacagatc attgacgatt ccataactat tattgaacat atatttccaa gcaaaaatca
    18841 aagaaataga tggcgtaaca taacttaata aaatcagtga acgcaccgtt ttcctaaatc
    18901 tgaacttgcg gttaagcaaa atagctacgg ctaatcctaa agctgtactg cctgctacaa
    18961 ctaagaatgt gtaagcaact gttaaaccta aagaacgata aaattcacta tcacttaaaa
    19021 tttcaagata attgcttaat ccgataaaaa cggcgtctga gttaggattc agcggcatat
    19081 cgaaaaaact gatctgaata ttggaaagca ttggaatcag cactaaaaca gctaataaaa
    19141 gcatgcttgg tgctaaaagt cccatggcta attttaagtc agaatgtttc cttggacgat
    19201 tcattgaaac ctccccctga taatctgcca atagctatct acttttttcg aacaccattg
    19261 gcagaacttc ttgttatttc gtattttttt gtgcgtcagc taaagcttga tcgacatctt
    19321 cgtttccgac agttacttgg ttcactgctt ttccgatcac acctgagctt gtgatatctc
    19381 ccattttcgt gaaattcttt tccccgacta gtccaaagac ttgtacttca tcaaaagcac
    19441 tagcaatctc agatggcagc tcgccaaaag acttgatgac ttcattttct ttgtaaccat
    19501 ccagttcgac tacttgttta ttcactggtt gagcaccacc aggagacatc aagacccact
    19561 tttccatgtt tttcggttga gataagaaag ctgtgaatgc ttcagcagcc tctttttgtt
    19621 tctcgtctag accagaagaa atcgtcaatc cagatactgt gccatagaca gcttgatctt
    19681 tttgtgttgg gatagcaaaa ccgatatttt ctgagttccc cgcttcataa acagaaggca
    19741 aaatgtaagt tgaatagatt gccattggtg ctgttccatt catgaaagca tctttgattt
    19801 ctgtcacatc attagagcct ggcatcgtgt attgggataa gttttgataa aacgacaatg
    19861 cttctctcat cttttccgta tcgatcgtta cctcgccttc atcatccaaa acatttgctc
    19921 catttgacaa agcaaattga gagaacgctt gctcactcat tgttccttca gcagtaggca
    19981 tagcaattcc atattgttta ttctctttat ctgtgaaatg ttgagcaatt tttaaaatat
    20041 catcccaatt ttctggttct gaaaaaccag cttctgataa tttttctttg tcataccaaa
    20101 taccttgaac ccagccgcta attggtgcag caatatagct ttttccatct tctgaacgaa
    20161 caaggttttt ggctccgtca taataattat cttctccagc ttcctcgata acgttttgga
    20221 ctgccgtctg atcaatcagt tcatctttat ccatcacttt agcaaaatcc tgactgactt
    20281 ccattacttc tggtaattta ccggaacgag ctaacgtaac gatttttgta ttgaacgctg
    20341 attcttctac cggcacttgc ttgattttga tgtctggatt ttctttttca aaatcagcaa
    20401 ccagttcatt gatcacactt aatcgttcct gttcgacaga agagtgcatg aattgaatcg
    20461 ttgtctgttg tgattcgtta gagctttgac tttcaccaca agcagtaaga agaaatccag
    20521 tagctagcag acaggtagta acaataattt ttttcatttt tttccacctc ttattttatt
    20581 attttcagcc acatatattc atacggctgg aatatcaact ttcgttcttg actgcaatgg
    20641 ataatttgtc cagaaaacag gtctaggtaa tctccttttg gtaaaagata acctgctgat
    20701 tgattggaaa aattatggat aactaagact ttctcttcct tcgcttcgcg aataaaactg
    20761 ataaaagaat ctgctgagtc cagtaagtaa atcaaactat tcggatggaa ggctttttct
    20821 ttttttcgaa tagatagcat ctgggtcaat tcaccatata ctgctgttct taatggatct
    20881 gtctgcaact ctttctcaat atctgctaac aaaaattttt gccgattgat ttttcgattc
    20941 tctcctgttt tttctacgcc tttgtaatca tttcgacttc ccagcacact ttgaatataa
    21001 attgccggca cgcctggtaa cgttaccaaa aatgaatgag cagctaaaaa gcgtttgctt
    21061 ctccattccg tcgtatctgt tggagaactt aacgcatcta gatacgtagc gtttatctca
    21121 tatggactgg tcgttccatc tgggtttttc ttgtagttta ctcgggcacc ctctttcttc
    21181 agctgttcca ctaattcaag gatcgttttt tccggcagaa tacctcgtac cggattcaat
    21241 ccgataccgt catgggaggc taaaaaatta aaaaaagttg tttttttcga tgcgaaatcg
    21301 atggttttta accattcttt caacttactt gtattacccg aacgaatcgc ttgaagggtc
    21361 aaaggtggta gcgaaaactg atagaccatc tgtgcttcat tctcgccatt cccaaaataa
    21421 ctgatattat ctttgtgtgg cacatttgtc tcagtgatca ataccgttcc tggagctgct
    21481 tcatcagcga ttgcacggaa taattggatg attttatgcg tttctggcag gtgtatacaa
    21541 gaagttccta gttctttcca taaaaatccc acagcgtcca agcgaataaa tgaagcgcct
    21601 ttttctaagt aaaacaaaag aatatcgatc attttcaata aaacttctgg atttttaaaa
    21661 ttcaagtcta cttgatcttc gctaaaagtc gtccatacgt gtttttcttt cccgtttttg
    21721 tcaatgaacg ttgtaagtaa cgggctggtc cttggtctag tcacgctgct tgtatctgta
    21781 tccagtggca aatcaataaa aaaatctttg tacgtatcat tcaagtttaa atattcctga
    21841 aaccaagtac tttcggcaga catatgattg cagacaaagt cgaacattaa ccgtgtttcg
    21901 cttctcattt cttctatatc ttcccatgtg cccaaacggt cgttgattgc ctgataattt
    21961 acaacggaga aaccatcatc agatgtatat gggaaaaatg gcaagaaatg tacaactcta
    22021 aatgtatctg ccaaatactt ttgataaaat ttcttaaatg tacgcaaagt tggttgctgc
    22081 tcttcaaaaa attgatcccc ataagtaatc aagaaaatat cttcttcgtc ccaatgcagt
    22141 ttgcctgcct ggcctttctt ctgctgataa acactgactt tttgttcaat catagaggcg
    22201 gttttctcag acaaatctga gtcgcgataa atcgcttgta aaagttttgt atacatcgga
    22261 ttcccctttc ttttttggga gcgttcccaa cgatttgatc atattatgga aaacgcttac
    22321 tgtcaatagc atttttttaa ataattttga tatacacaaa aatacaaata agaaagctta
    22381 tgtatcaata attaatagct tcttaaaaaa atatggtctc tcatgatcat gcaagctatt
    22441 cctaaatttt caaaatcata gacaaaaaag aatgtctatt gtactatgga attattctaa
    22501 aacgctccca aaaaggaggt gcatataaaa ttgaaaccta ctatttatga cattgcgaaa
    22561 aaagctaatg tctcaaaatc aactgtctcc agagtattaa ataaccagcc aaatatctct
    22621 gataaagcaa aagcaagtgt acttcaagca atcaaagaat tgaattatga accgagcaaa
    22681 attgcaagag gactgtcagg aaatggtttt gacgcgattc tagcattatc tcatcgtact
    22741 tctcatacga cctatggcaa tccttttttt tcagatgtta ttcaatccat ttctgccgtt
    22801 tctgaacaaa ataacttcga cttgattcta caaacggcaa aaacaccaga agaagagcta
    22861 gaaaaatgcg cgaaaaagat ccaagaaaaa atgatccgag gaattattat tttaagctct
    22921 acgatggatg aaacacttct ttttgaattg gatcaataca atattcctat tgtggtaatc
    22981 ggaaaagtcg gaaacgacta cacgaacatc tactcagtgg acacggataa tttccaggat
    23041 agttacgatt tggtggaaac actgatcaag aatggacacc gtcatatcgg ctgtctccat
    23101 gctccgacag aagtttatgt atccaatgat cgtctcaatg gttaccgtca atgcttattt
    23161 gatcaccacc tagatatccg taatgaatgg attatagacg gcggctttcg cttagaagat
    23221 agcatggcag caatgaatga tttaatgaag ctacgagaaa gaccaactgc gattttttct
    23281 accgatgcat taaaatcatt gagtatttac aaagtggcag aacaatctgg aaagcagata
    23341 cctgatgatc tttcgatcgc aggattcagt gatcccttat tgtcctccct attttcgcca
    23401 cagttgactc ggatagacat tccgacaaat cagttaggaa tcaaagccac agaactttta
    23461 ttccaactaa tccaccacca ataccctgaa gaaaaaagaa tcattctttc aaccgagatt
    23521 actctcacag attcgatcca acaacaagaa atgtagaaca gaattataaa agaacagaaa
    23581 cactgaggat aagtcagtta ctctgttctt ttttcaatca ctcatccctc gttaccccct
    23641 cccggtattt tagcgaattt ttcttatttt ccatctgttt tagatagctg tggataacta
    23701 taatgtttgt gttaaactat tttttccaca gggaagaaaa aactattttt aaccacgttg
    23761 tgtataagtt tttatagttc gtttttttaa acacatttac ccttatttca atccatgtta
    23821 tttggggata cttatctcta aaacataaat agaataacag acatgtctac tggttttgtt
    23881 ttattcgagg aattattcaa taatagctag caaaatatta aaaataaccg ctctatcttc
    23941 ccatcaattt attttgcatt caaaaaatga tctatcttta cttttgttga ttgacttctc
    24001 ttggaagatg atcgttccga taccttaatt ggatacgaac cgatgttgtt aagatccttt
    24061 cccacttttc ttctagttag acaaattatt ttagacaaac caaaaaagag gttgtgacaa
    24121 taatttgtca caacctcttt tttaaaatat ctattttgtt tgattgttca ttgcgtcttc
    24181 tgcagccatt tgcgcttcaa tatctgaaat actgtagaca ttttcgcttg ctacaccgac
    24241 ttcttttggt tccatgtcac gataacgttg cataccagta ccagctggga tgatcttacc
    24301 tataataaca ttttctttca aaccaagaag aggatctttc ttaccgcgga tcgcagcatc
    24361 cgtcaagaca cgagttgttt cttggaatga tgcagcagat aagaaactat ttgtttctaa
    24421 tgatgctttt gtgataccta gtaagacagg tcgagaagtt gcaggaacgc ctcctgagac
    24481 tagcgtattg tagttttgat ctttaaagtc tgcgatgtct aataatgtac ctggtaagat
    24541 atctgtatca cctggatcca ttacacgaac tttacgcagc atttgacgaa ccattacttc
    24601 gatatgcttg tcgccgattt ctaccccttg catacggtaa acacgttgta cttcacgaag
    24661 caagtagttt tcaacagata atacatcgcg aacttgcaac aattgttttg gatcgattga
    24721 tccttctgtc aatggtgcac cacggtggat catatcgcct tctgctactt tcatacgtgc
    24781 tgtataagga acagtatacg tacgtgtatc tgtttttcct ttgattgtta cttctttggt
    24841 acgtgttgca ggatcttctg agatatcgat gacatcccct gttacttctg tgatcactgc
    24901 ttgccctttc ggattacgtg cttcaaagat ttcttggaca cgaggaagac cttgagtgat
    24961 atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc gtcaactgag taccaggttc
    25021 accgattgat tgagcggcga tcgtaccaac tgcttctccg acttcaacgt cagagccagt
    25081 tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt tttgtattac atgtgaagac
    25141 agaacggatt gtcactgttt cgacacctgc atcaacgatt tgttttgcga tgtcttcgga
    25201 aatcaattgg tttcctgcaa tgatcaattc atttgtttca ggatgacgta cttctttacg
    25261 ggtgtaacgt cccactaaac gatcttctaa tgattcgatg atttcatttc cctcgcggat
    25321 ggcttggatt tcaagacctc ggtcagtacc gcaatcttct tcacggatga ttacatcttg
    25381 ggccacgtca accagacgac gagtcaagta acctgaatcg gcagtcttca aggctgtatc
    25441 ggtcatccct ttacgagccc cgtgagttga gataaacatt tccaagacgg atagtccttc
    25501 acggaagttc gaaatgattg gcaattccat gattcgacca ttaggagcgg ccatcaaacc
    25561 acgcattccg gcaagctgtg taaagttgga aatgttacca cgagctccag aatcagacat
    25621 catgaagatt ggatttttcg cttccaaacc ttccatcagt ttttgttgga tgctgtcttt
    25681 tgcagcattc caaacagcaa tgacacgttc ataacgttcg tcatctgtga tcagaccacg
    25741 acggaattgt tttgtaatag tttcaacttg tttatgggca ttttcaatga tttcttgttt
    25801 ttcattcagt acactgatgt cagcgatccc tactgtgata ccggcatgtg tcgaatgttt
    25861 gtaccctaag tctttcatac ggtcaagcat cttagaagtt tcttttactt tgaatcgttt
    25921 gaagacttct gcgatgatgt ttcctaagtt tttcttcttg aacggtaata ctaattcttg
    25981 ctctttgata tgtgcaggaa tatcagtacc agcttcaaca aagtatttgt ccggtgtttg
    26041 gacggtcaag ttgaagtctg ttggttcatt cagataaggg aattcaggag gcatgatctc
    26101 gttgaagatg atcttaccaa ctgttgtgat catcgtacgt tctttttgcc attcagtaaa
    26161 tggtttttca cctaatgagt tagggttcac accgatacgt gaatgtaaat gaacatatcc
    26221 gttgcgccat gcgataacgg cttcgttttg atctctgaag accattcctt cgccttcgcg
    26281 tccttcttct tccattgtca agtagtagtt acctagaacc atatcttgag aaggagtaac
    26341 aactggttta ccatctttag ggttcaagat gttttgagca gctaacatca acatacgtgc
    26401 ttctgcttgt gcttcttcat tcaatggaac gtggacagcc atttggtctc catcgaaatc
    26461 ggcattataa gcttcacata caagtggatg caaacggatt gcgcgtcctt gtactaaaac
    26521 tggttcgaat gcttggatac caagtcggtg aagcgtaggt gcccggttca gcaatactgg
    26581 gtgttccttg attacgtctt ctaaaacatc ccatacttcg tcttcttgac gttcgatttt
    26641 acgtttcgca tttttgatgt ttgaagctag ttcgcgttga acaagctcac gcatcacgaa
    26701 tggtttgaat aattcaatgg ccatttcttt tggaagtcca cattggtaca tcttcaagaa
    26761 aggtccaaca acgataacgg aacgacctga gtagtcgaca cgtttaccta gcaagttttg
    26821 acggaaacga ccttgtttcc ctttcaacat atgagaaaga gatttcaatg ggcggttacc
    26881 tggtccagta actggacgtc cgcgacgacc gttatcgatc aatgcatcta ctgcttcttg
    26941 cagcatacgt ttttcatttt gaacgatgat tccaggtgca ttcaagtcta acaaacgttt
    27001 caaacggtta ttacggttga ttacacgacg gtaaagatca ttcaagtcac ttgttgcaaa
    27061 acgtccacct tctaattgaa ccattgggcg taaatctggt ggaataacag ggataacgtc
    27121 cataaccatc cagcttggtt gatttcctga agcgcggaat gcttctaaaa tatccaaacg
    27181 gcggattgca cgtgtacgtt tttgtccttg tgcagatttc aattcttctt tcaattcggc
    27241 tgcttctgca tctagatcaa cattatcaag taattgttta atcgcttctg cacccatagc
    27301 agcttggaat tcttgtccat attgttcacg tttttcgcga tattcgcgtt ctgtcaacaa
    27361 ttgttttttc tctaaattcg tatttcctgg ttcgatgact acatatgaag caaaataaat
    27421 gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga cccatacgtg aaggaatccc
    27481 tttaaagtac cagatatgtg aaacaggagc tgctaattca atatgtccca tgcgttcacg
    27541 gcgaactttc gaacgagtaa cttccactcc gcatcgatca caaacgattc ctttataacg
    27601 gatacgtttg tattttccgc aggcacattc ccagtctttt gtaggaccaa aaatccgctc
    27661 acagaacaac ccttcgcgtt caggttttaa ggtacgatag ttaatcgtct caggtttttt
    27721 tacttcaccg taagaccagc ttctgatttt ttcgggagaa gccaaaccta tttgcatact
    27781 ttcgaattta tttacatcga tcaaaagggg ttccctccat ttcatttaat ggcaaaccgc
    27841 aagacggctg atcttcgacc gccttgcagc tcatagaccg gattagtcta aattatcttc
    27901 tgcggtttca aagttttgga tgacatcgtc tttttcatct tccacttgtt cagcagcttt
    27961 cttttctaat tctttggcag tttgctgttc ggcaaatttt gtcaaagcat caacagtgat
    28021 caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc tctgtttctt cgatatccaa
    28081 gacacgcatg tccagaccta gtgattgcaa ttctttcacc aatacgcgga atgattccgg
    28141 tacacctggt tttggaattg gttcaccctt gacgattgct tcgtatgttt tcacacgtcc
    28201 gactacgtca tctgatttgt atgtcaagat ttcttgtaaa gtataagccg caccgtaagc
    28261 ttccagtgcc catacttcca tttcaccaaa acgttgtcca ccaaattgag ctttacctcc
    28321 caatggttgt tgtgtaacca atgagtaagg tccgattgaa cgtgcatgca atttgtcatc
    28381 gaccatgtga gcaagtttga tcatgtacat cacaccgaca gacacacgtc catcaaatgg
    28441 ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg ctggccatac cggcttcacg
    28501 aactgtttcc catacgtctt catcacttgc accatcaaat actggcgttg ctacgtggat
    28561 acctaactga cgtgcagcca tacccaagtg taattccaat acttgcccga tgttcatacg
    28621 tgaaggcacc cctaaaggat tcagcatgat atcgattggt gttccatcag gtaggaatgg
    28681 catatcttct tccggcataa tacgggatac aaccccttta tttccgtgac gaccggccat
    28741 tttatcccct tcatggattt tacgtttttg aacgatataa acacgaacta acatgtttac
    28801 gcctggtgac aattcatctc cagcttcacg agtaaagatt ttcacatcgt gaacgatacc
    28861 gccgccgcca tgtggtacac gtaatgatgt atcgcggact tcacgagctt tttcgccaaa
    28921 gatcgcatgc aatagacgtt cttctgcaga taattctgtt accccttttg gcgtgacttt
    28981 ccctacaagc aaatcgccat cttggacttc tgcaccaata cggatgatac ccatttcgtc
    29041 taaatctttt aatgcgtctt ccccgacatt agggatttcg cgtgtgattt cttcaggtcc
    29101 taattttgta tcgcgggctt ctgattcata ttcttcaata tggatagaag tgtatacgtc
    29161 atcttttacc aaacgacggc tcatgatgat cgcatcttca tagttgtacc cttcccaagt
    29221 catgaaacca actaaaacgt tttggcctag agccatttcg ccttgttcca tagatggtcc
    29281 gtctgccaga gtatcccctt tttcgacttt ctcacccaaa tgaacgattg gacgttggtt
    29341 gtagcttgtt ccggagtttg aacgacggaa ttttgttaca tcgtatttat ctaatgcacc
    29401 gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat tcaacgacac catcatgttt
    29461 acataacaaa gcagctcctg agtcatgcgc tgatttgtat tccataccag taccaaccca
    29521 tggtgcttga ggattgatca acggcactgc ttgacgctgc atgttggcac ccatcaaggc
    29581 acggttggag tcatcgtttt ccaagaaagg aatacatgct gtcgcaacgg caactacttg
    29641 tttaggtgat acgtccatgt agtctacttt atcaatagat acttctaagt tttcactttg
    29701 agcacgagcc ataacaacgt cttgagcaaa tgttccatct tcattcaatg ggctgtttgc
    29761 ttgggctacg atgtaatggt cttcgatatc agctgtcaag tagtcgattt ggtcagtaac
    29821 acgacctgtt tcacggtcta cacgacgata aggtgtttcg ataaatccga atttatttac
    29881 tttcgcataa ctggacaaac tattgatcaa cccgatgttt gggccttcag gagtttcgat
    29941 cggacacata cggccatagt gggagtagtg aacgtcacga acttcataac cggcgcggtc
    30001 acgagtcaat ccgccaggtc ctaaggcgaa aagacgacgt ttgtgtgtca attcgccaag
    30061 agggtttgtt tgatccatga actgtgacaa ctgagaagaa ccaaagaatt ctttgatact
    30121 tgccacaact ggacggatat tgatcaattg ttgaggtgtc aatgtttcag tatcttggat
    30181 cgacattctt tcacgaacca cacgttccat acgtgctagc ccgatacgga attggttttg
    30241 taaaagttca ccgactgaac ggatacgacg atttcctaag tggtcgatat catcgacatt
    30301 gccgatacct tccatcaagt tcaagaaata gctcattgaa gcaatgatgt cggctggacg
    30361 aaccgttttt acagctgctt ctggatagcc gtttccgatc acgtttactt cacgttcagg
    30421 gtctcttggt gaaaatactt tgatgacttg gacagtcatt ggatctgtga ccacaccgtc
    30481 ttctgatgga tagtaagtca ctgaatttag gccattatca atgaaaggag ctagtgtttc
    30541 catgacttgg tgagtcagaa ctgttccttt ttcaacgatg atctcgcctg tttctggatc
    30601 aactaatgtt tcagctaatg tcagattcaa tagacgtgtt ttcaaatcta attttttgtt
    30661 tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt ggatcgaaga aacgagcatt
    30721 cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct ggacgcaaac gttcgtaaac
    30781 gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt ttatgcaagt ctttttcgac
    30841 tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag atcgtatcat cggaaccaaa
    30901 tcctaacgca cgaactaata cggttaaagg aatcttacgt gtacggtcga tacgtacata
    30961 agagatgtct tttgcatcag tttccatttc tagccaagct ccacggttag ggataacagt
    31021 agaaccgaat ccttcttttc cgtttttgtc gacttttcca tggaaataga cacctggtga
    31081 acggactaac tgagaaacga ttactcgctc tgccccgttg atgatgaatg ttccttgttc
    31141 tgtcattaat gggaaatcac cgaagaatac ttcttgtgct ttgatttcgc cagtctcgcg
    31201 gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag tttgcatcat gcgcacgagc
    31261 ttctgctact gtatactttg gttctttcaa ttcataatct acaaattcca aagatagatt
    31321 gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt tctctaagtc cctcatctaa
    31381 gaaccattgg taagagtctg tttgaatttc gatcaaattt ggtaattcca acacttcact
    31441 gattcttgcg aaacttctac gttcgcgatg ttttccgtat tttactacgt gtccagccaa
    31501 gctcttcacc cctctaaaat gtcattcaaa aagactaccc gatcaattgt tacaataata
    31561 tttcaaatat tatttttagg taacaacaga cattttttgc ggcttttagg caaaaaaaaa
    31621 ccaaaaatag aacattctct tgaaacctta cttcgtgagc ttctactttt gtttccttat
    31681 attaaagccg aaacggacaa tatttcgttt ctgccttttc ttcatcagat agtttttgca
    31741 acttcatata ctacacttat tttctataaa agtcaacact tcctggcgtt tcttctgctt
    31801 tttcgcaaca ttttcttaat gttttcaatt ttatgttttc aattatctga caattcttaa
    31861 ttgacagacc tttttatctc ggttatactt tagaaaattc attttgtgga ggaacttcta
    31921 tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa taacttttac tttagctact
    31981 ttagataggt ttgtattcat catgatggat acaaacgtta aacgacagtt tgtatctatg
    32041 atggctaaag aactttgtat tgcagcaaaa agccacgtag acaaaatgct aagtggctga
    32101 gcagtgaaaa tacaaagtaa aagtatcaag cattctactt tttcaattta ttttccgact
    32161 tttcaatcca tttggacatt ttgtctgaat ggattttttg tttcccaaaa ttaaggagga
    32221 aaaagaaatg aaaaaaaata taatcatcgg attaggcgct gccctgctac tagctttagg
    32281 aggttgcgca caaaaagaca attccgcaga ggcatcagat ggacaaaaaa caattggcgt
    32341 attgcaactt gtacaacata actcgttaga tgctgcctat aaaggattca aagaaggatt
    32401 agcagaagaa gggtataaag aaggcgataa tctaacaatc gattatcaaa atgcccaaaa
    32461 caatcaagac aacctgaaaa gtatgagtga gaaactcgtc aaagaagatc ctgatttgct
    32521 acttggaatc gccactccag cagcacaatc tttattaaat gaaacaacca ctatcccgat
    32581 gactgtcaca gcggtcacag acttggaaca agcccattta gtcacatcca atgaaaaacc
    32641 tggcggcaat gtgactggca cgacagatat ggtgccaatc gaaaaacaaa tcggcttact
    32701 gttaaatatc gtgccagacg ccaaaacaat cggcatcatg tataacaacg gtgaagcaaa
    32761 ctctaagatc caagctgatt tggcagaaaa agaattgaaa aaagcgggcg tcaaagtcaa
    32821 agtactgaca gcaaattcca caaatgatgt ccaacaagtg acgaaaagtc tagctaaaga
    32881 tgtagatgga atctatattc ctactgataa cacgttcgca agtgcggcaa gtgttgtcgg
    32941 tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc gcagttgatc aagtcaaaga
    33001 cggcggtcta gcaacagtag gaatcgacta cgaaagcttg ggcaaacaaa cagggatcat
    33061 ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt cctgtcgaaa cagcgaatga
    33121 tttggaactg tatgtcaata aagacatggc caaagcatta ggcatcaatc cagacagcat
    33181 caaagaagct gaataaaaca caggaggatt ctcatgacaa atttgctctc tcttttctta
    33241 tcatctgcat cgcaaggggt cttatgggcc ctacttgcga ttggtgtata cgtcactttc
    33301 cgtatcttgg acattgccga cttgactgct gaaggaagct ttcctttagg tgcagggatc
    33361 gcggcagtaa gtattacaaa tggctatcat ccattgacag cttgtcttct aggcttttta
    33421 gggagtgcgg cagcagggct tgtttccgga ctgcttcaca caaaattgaa aattcccgcc
    33481 cttcttgcag ggatcatcac catgactggt ttatattctg tcacatcccg tgtgatgggt
    33541 gcgccgaaca tctctttatt gggtcagcca acgatctttc attgggtcga gtcattcggc
    33601 ataacaaaag acaacgctgt actgatcgtc ggtctgcttt ttgctttgat cgttgtatgt
    33661 ttacttgttt tgttcttacg tacagaaaca ggacttgcta ttcgtgcaac tggcgataat
    33721 ctggcaatga gcgaagcaaa cgggatcaac acagataata tgaagatcat cggttatatg
    33781 atttctaatg gatgcattgc tctttctggc tccttgcttg cgcaaaacaa cggctttgct
    33841 gatttaaatt ctggtattgg aacgatcgta attggacttg cttctattat catcgcagaa
    33901 gttttgttac gtaaccagcc actatttctc cgtctcttga ctgtcgtttt aggtgcggtc
    33961 atttatcgtt ttattttagc gttagtcttc gaactgaatg ttgaaccaag tgattcgaaa
    34021 cttgcttctg ctttcgtgct agtgatctgt ctttctttcc cgcagatcca gcaaaaattc
    34081 catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa tgacgtctta acattggaaa
    34141 atctccatca tacctttgaa aaaggaacga tcaacgaaaa tcatgtcctg aaaggcatta
    34201 atctttcctt agatcccggc gacttcgtga cgatcatcgg tggaaatggg gctggtaaat
    34261 ctactttgct gaacagcatc gccggtacat tttctgtcga tcagggtcaa attttattga
    34321 atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc gaaatccatc agtcgcgtat
    34381 tccaagatcc taaactaggg acagccgttc gtttaacggt agaagaaaat cttgctcttg
    34441 ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt caaaccacaa gaccgaacat
    34501 ttttcaaaga ccagctggtt cggctaaatt tggggttgga aaatcgttta tcctcagaaa
    34561 tcggtttgct gtctggagga caacgtcaag ctattacgtt attgatggcc acattacagc
    34621 gtccagaact gatcttatta gatgaacaca ctgcagcgct tgaccctgct acttccaaaa
    34681 cggtgatgga attgacagaa aagctgatca ctgagcagaa tctcactgct tttatggtca
    34741 ctcatgacat ggaagacgcg atccgctatg ggagtcgact gatcatgctg catcaaggaa
    34801 ggatcgtcgt agatatccag caagaggaaa aacagcagct cacagtgccc caattattag
    34861 cgttgttcaa acaaaacagc ggcacggcat taaaagacga tcaagtactt ttatcttcat
    34921 aatcagaaag aggatgggac aaaaaatgaa cgcccaccct cttctttttt ctctttcctt
    34981 ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga aaactatttt gttctctcct
    35041 tcttcctgat agaatggatg ggaaaggagc ttgatgccat gacaacgaaa gacaaggtac
    35101 ttcaattatt gaaaaagaca ccagattttc tttccggaga aaagttggca cagcaactgg
    35161 aagtttcccg gacaagtatt tggaaagcca tcaaagaatt ggaaaaggca ggctatcgtt
    35221 ttgagcacgg gcctacaggg tatcgttacc tgccctctga cgtactagat gcaaaagaaa
    35281 tccagcaaga gctacggtcg tttattcctg atttgaaagt acaaacgatg atgacttctg
    35341 aatctacgat gaaagatgcc aaactggcag cagctcaagg agattctgtt tcgaagttat
    35401 ttgttgctga tacacaagaa caagctcgtg gacgttttgg acggcctttt ttcgctgaac
    35461 ctggacgagg aatctacatg agtctcttgc tccatccaga caaacggttt gatgaattgc
    35521 ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc cattgaatct gtaaccggtc
    35581 gttctgcttc gatcaaatgg gtcaatgata tctacatgga tggaaaaaaa gtctgtggga
    35641 ttttatctga agcagtcagt gatatggaaa gcggcaggat cagtcatatc atcattggga
    35701 tcgggcttaa tttttctgtt cctcaaaatc attttccagc tgatctccaa gaaaaagcca
    35761 tctctgtctt tcccgacgga caagctagtg tcacaaggaa tcagctaatc agcaaaatct
    35821 ggcaagaatt gttcacttat ctttctcacc cagaaaaagc gttggacttc tataaagaaa
    35881 aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa aggaacgact tatgtcggtc
    35941 ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca aacaaatgaa cagaagatga
    36001 gtttgtcttc tggcgaaatc agtctcacat ctatccgtac gcaataatta tcagatttca
    36061 caaaaggaca cctgatctca tacagtgtcc ttttttctga attctcttca aaagactctc
    36121 cttattctat cagctgacag tttctctatc ctctagaaaa aggtattcta aaaatatcta
    36181 taaagcatgg tacactttct ttaaatgaat caatgcaaaa aacaagagag tcatcagttt
    36241 acacgatcaa aagagatagc aggccgcttc ctttttcaat cttatagata gaccatgggt
    36301 aacgataaaa acaaaaaaga acttgcgact tattttgccg taagttcttt tttagctagt
    36361 gccttaatct cttaatccca acaaacgtct cgcatagatc acctgaccag agtgcatagc
    36421 agcatcatca ataatagaaa cgagacgcat tcctcgtgtg actggtggtg tccagttctc
    36481 gtcaattact tcatctagct cggaaggttc cagccttctt aagtaagaaa tagcaaaatc
    36541 agcagctcct cgcaagtatc ctagcagatc ttctatttga ttagcttgga tctgctttgc
    36601 ttgttccaga ctatgcttcc aatcttgttc gttatctgct atcgtcatcg gaaaccggct
    36661 ttcccagtct tgactatgcc aaattggaga agttcctgct aaatcagcaa tctggaaatc
    36721 taattctcga gcggtatgcc aagccagcca agtcattgat ttgatctgcg gggctctatc
    36781 ttccactgga aaacgattgg cctcctcaat agagacgcct tcaaacaaac gttcaaaccg
    36841 atcgtatgcc cgatccacac tctcgcatag catatctaaa taatccattt attttcctcc
    36901 tttttattta tcctacttac tttttcctaa ttctaggata cctacttata tgttactaca
    36961 cacccttatt ttttacactt taacagtcac catcatcaat agtttggaga ttgaaagaaa
    37021 aagatagtgt cgaactatca attgaacaag aagcaacaat atgaacgttt cattaatatt
    37081 ctttaaataa acaatgattt ttcaaacgaa cagtttaaga ctaggagaaa aagagtataa
    37141 taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa aaaagggcaa gtttactagt
    37201 cctagttgct ttgttgttca atatcttttc gtatggtgtg gccgtttcag cggaaacata
    37261 cattcctaaa gaccctggga atatttataa tgatctaact ggtaactatg gcttgttagg
    37321 aattgctagt caattccacg tatttgctaa aaataagaca actgtgaatg cacatacaga
    37381 cggaaatata gcaacacatg aacttgatgc aaaaaataat tttggtacag agcttcatga
    37441 aggtttattg aaccaagaaa taaattatat acaaaaaact gattctttcg ctaattcttc
    37501 aggcatacct acaggtagca caagaatgaa taaatttgtc gttggcagta acgtggatgt
    37561 agcacttcaa gatggtcatc ctacagtcaa tggatccagg cttgatcact taactccaga
    37621 tgatttttat aaagatcgtg ctgggcatga atatattgat ttcgagcagg aatttgctaa
    37681 attgaatgta gcagcaaatg atcttgcaac gatcactcca gctaaaacat atactgctgc
    37741 agattttcca gacatgaaca atcggacaat cgatttaact gatttatcag ataccgggtt
    37801 tttattggta aatatcgatg cagaagtgtt aacgatgaat acgccacttc aaatcattaa
    37861 tccaaatgat caagtagttg tatttaatgt catcaacagt tcttctgcat tgaacgtaca
    37921 gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca gaagattttt cggatgcgaa
    37981 tatctcttgg aattttggaa atgagatgac tgatttgaca atcagtgctc cttttcaagg
    38041 aacaatcctt gcgcctaatg ctactatccg cattactcaa aaccaagacg gaacgattat
    38101 aggaacaaat gtgattttag atgcagctac caatcgttgg gatcctaacg aaatatttat
    38161 cagcgacaat ggtacagata cgacagacac aagcgacagt acagatacat ctaccacaag
    38221 tgatagctca gattcatca
//
LOCUS       DAFLWQ010000020        37244 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.021, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000020 DAFLWQ010000000
VERSION     DAFLWQ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37244
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.021"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..839
                     /locus_tag="L1V16_001015"
     CDS             <1..839
                     /locus_tag="L1V16_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1275370.1"
                     /translation="YQLVETQAPTGYELDATPIEFEIERSQTAVVELTKANRLTPGGV
                     VLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGVYQLVETQAP
                     TGYELDATPIEFEIERSQTAVVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDA
                     NGTVLQSGLTTGADGKLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIF
                     LTKENRKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKR
                     NI"
     gene            complement(1263..1433)
                     /locus_tag="L1V16_001016"
     CDS             complement(1263..1433)
                     /locus_tag="L1V16_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1275371.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1627..1806)
                     /locus_tag="L1V16_001017"
     CDS             complement(1627..1806)
                     /locus_tag="L1V16_001017"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275372.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            complement(1816..2040)
                     /locus_tag="L1V16_001018"
     CDS             complement(1816..2040)
                     /locus_tag="L1V16_001018"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275373.1"
                     /translation="MNGSIKKILRSIDKNLMITEVSYETLQKKKTLIVAAVLFPAPCV
                     CRNCGSAVVDGNRKLMVVKNKKKETIVHFE"
     gene            2193..3305
                     /locus_tag="L1V16_001019"
     CDS             2193..3305
                     /locus_tag="L1V16_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBN1275374.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(3383..3676)
                     /locus_tag="L1V16_001020"
     CDS             complement(3383..3676)
                     /locus_tag="L1V16_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBN1275375.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3844..4158
                     /locus_tag="L1V16_001021"
     CDS             3844..4158
                     /locus_tag="L1V16_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HBN1275376.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4179..6158
                     /locus_tag="L1V16_001022"
     CDS             4179..6158
                     /locus_tag="L1V16_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBN1275377.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            6171..6497
                     /locus_tag="L1V16_001023"
     CDS             6171..6497
                     /locus_tag="L1V16_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HBN1275378.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            6513..7031
                     /locus_tag="L1V16_001024"
     CDS             6513..7031
                     /locus_tag="L1V16_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275379.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            7031..8383
                     /gene="celB"
                     /locus_tag="L1V16_001025"
     CDS             7031..8383
                     /gene="celB"
                     /locus_tag="L1V16_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBN1275380.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(8467..9972)
                     /locus_tag="L1V16_001026"
     CDS             complement(8467..9972)
                     /locus_tag="L1V16_001026"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HBN1275381.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(10064..10654)
                     /locus_tag="L1V16_001027"
     CDS             complement(10064..10654)
                     /locus_tag="L1V16_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1275382.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10833..12479
                     /locus_tag="L1V16_001028"
     CDS             10833..12479
                     /locus_tag="L1V16_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1275383.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            12528..13247
                     /locus_tag="L1V16_001029"
     CDS             12528..13247
                     /locus_tag="L1V16_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBN1275384.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13726..14673
                     /locus_tag="L1V16_001030"
     CDS             13726..14673
                     /locus_tag="L1V16_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1275385.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14685..15605
                     /locus_tag="L1V16_001031"
     CDS             14685..15605
                     /locus_tag="L1V16_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1275386.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15646..17103
                     /locus_tag="L1V16_001032"
     CDS             15646..17103
                     /locus_tag="L1V16_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1275387.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            17448..18062
                     /locus_tag="L1V16_001033"
     CDS             17448..18062
                     /locus_tag="L1V16_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBN1275388.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            18055..19779
                     /locus_tag="L1V16_001034"
     CDS             18055..19779
                     /locus_tag="L1V16_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBN1275389.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19776..21227
                     /locus_tag="L1V16_001035"
     CDS             19776..21227
                     /locus_tag="L1V16_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1275390.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21699..23852)
                     /locus_tag="L1V16_001036"
     CDS             complement(21699..23852)
                     /locus_tag="L1V16_001036"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HBN1275391.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23854..24900)
                     /locus_tag="L1V16_001037"
     CDS             complement(23854..24900)
                     /locus_tag="L1V16_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1275392.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            25050..26339
                     /locus_tag="L1V16_001038"
     CDS             25050..26339
                     /locus_tag="L1V16_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HBN1275393.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            26352..29054
                     /locus_tag="L1V16_001039"
     CDS             26352..29054
                     /locus_tag="L1V16_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBN1275394.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            29039..29896
                     /locus_tag="L1V16_001040"
     CDS             29039..29896
                     /locus_tag="L1V16_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1275395.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(29967..30866)
                     /locus_tag="L1V16_001041"
     CDS             complement(29967..30866)
                     /locus_tag="L1V16_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBN1275396.1"
                     /translation="MVQLVCNCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            31035..33206
                     /locus_tag="L1V16_001042"
     CDS             31035..33206
                     /locus_tag="L1V16_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBN1275397.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            33274..33615
                     /locus_tag="L1V16_001043"
     CDS             33274..33615
                     /locus_tag="L1V16_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBN1275398.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(33891..35645)
                     /locus_tag="L1V16_001044"
     CDS             complement(33891..35645)
                     /locus_tag="L1V16_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1275399.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLSFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQCISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(35656..36492)
                     /locus_tag="L1V16_001045"
     CDS             complement(35656..36492)
                     /locus_tag="L1V16_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBN1275400.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(36494..37177)
                     /locus_tag="L1V16_001046"
     CDS             complement(36494..37177)
                     /locus_tag="L1V16_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HBN1275401.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
BASE COUNT        12013 a         6553 c         7638 g        11040 t
ORIGIN      
        1 catatcagct ggtagaaact caagcgccaa cggggtatga attagatgcg acaccgatcg
       61 agtttgagat cgaaagaagt cagacagcgg tggtagaatt gacgaaagca aaccgactta
      121 caccaggcgg tgtcgtgttg acaaagatcg atgaccaaag cggggaagtc ctgcaaggag
      181 ctgtttttga gttacaagat gccaatggaa ccgttctgca gtcaggtcta accacaggag
      241 cagatggaaa actggcgatt gacggcttag caccaggagt gtatcagctg gtagaaaccc
      301 aagcgccaac ggggtatgaa ttggatgcga caccaatcga gtttgagatc gaaagaagtc
      361 agacagcggt ggtagaattg acgaaagaaa atcgacttac accaggcggt gtcgtgttga
      421 caaagatcga tgaccaaagc ggagaagtcc tgcaaggagc tgtttttgag ttacaagatg
      481 ccaatggaac cgttctgcag tcaggtctaa ccacaggagc agatggaaaa ctggcgatag
      541 atggcttagc accaggagca tatcagctgg tagaaactca agcgccaacg gggtatgaat
      601 tggatgcgac accagtaact ttcaagatcg aaaaagaaca agaagtggcg atctttttaa
      661 caaaagagaa tagaaaagtt gctgatagct cagatataag aggaaacaat ccaacaagca
      721 gtggaaataa gcatcttcca aaaactggag aaaccatcat tagccagttt atattgtcaa
      781 tattgggtgt gctacttgtt ttcatcagta taaaatttag aaagaaacga aatatatgag
      841 ctaaaataaa aaattgaata agcatagttt ttaaaatcaa ctagtaccca tcaattgaat
      901 ggaaactacc gattttagaa ggggtataca aacaaatatt agtatcggag tagagaaggt
      961 tgaacccaac cagtaaataa gtaaagacaa ttttgtgctg cgttgagaag tgaaaaataa
     1021 acctttgtag taatactagt taataaaaaa tatacaaaaa cactgcgaaa atcattcttg
     1081 agtttcgcag tgttttttgc ctaatgactc aagtttattg ggtaatactt tgattttctt
     1141 tctacaaata atcagcgatc agttgtaatt ttttctctag ttttaatggc tctttgtcaa
     1201 taaggagaaa aacaagtcgg gtcttttgtc tcggaaagct tcaaccaact cgtgaataaa
     1261 ggttacgcct ccttgaaagg cgtggaaaaa ccaagtaatc gatcaatcac caatttcgca
     1321 tttggtagaa catgtttggt gagctgaaag taggtggcgt tcatgtctgt aactaagaat
     1381 tctatttctt taggattagt gcagctaagg aaatagtttg ttaatcgagg aattttttgt
     1441 gtaggtaaat tttctcgatt aatttttctg tctcgccatc cgcggaaata aaactcagtt
     1501 tatcctcaac ggaaacgtga gaacgaaatt cacaaccctc aacactcaag acagaattct
     1561 tttggaagac tttggtaaat agcttctcaa ctctttcaat gtgcgaataa cggttgtcaa
     1621 agatacctaa caacttttcg aaataaaaaa taacgacact ttttcagtca gtaaagaagt
     1681 gattttatgt ctgacatgat ttgaaatcga gtgccttgga cggataaaat aactttgagc
     1741 gttccaatgg cttcgacagt ttttacaggt atagcgctgc ttttttaggc gtataaccat
     1801 tggcatatga ttatattatt caaagtggac aatggtttcc ttcttcttgt ttttcaccac
     1861 cattaatttc ctatttccat ctaccacagc agaaccacaa tttctacaga cacatggagc
     1921 agggaagaga actgcagcaa cgatcaatgt ttttttcttc tgtaaggttt cgtaagagac
     1981 ctctgtaatc atcaaatttt tgtctattga tctcagaatt tttttgatag aaccattcat
     2041 aaagcatatc gttctctcag ttgtttattt tgtggtgatt taatcataca agaaaacgat
     2101 atgttttttt ataaaaacat gaataggaaa aatagttgac aagaaaatga caacgccata
     2161 tgatgttcca tagtatttac aacctgtcat agatgactgt aaaaaataaa agtaaaaaga
     2221 aaggacgaca acaggtggat ttttatcagt ctctacaact agatccgttt attttaaaac
     2281 aaaaaatacg agaagcagct tctaaaaaag aaaagtgcat gtatatttgt tcattgtttt
     2341 tacgatcatt attcatcgta ttgtttgcca tttgttttat cattataatt acaacattat
     2401 ttgaatcgaa gcataaacca tacgctgtgg ttttattctg tatgttgatg agtattcgtt
     2461 ttgttgactt tggttataag atttcccatt cgatcatagg tttagcaatc gtcatgttct
     2521 cactattagt agcaccgtat gtccagctga tcaaatggtc agttatgggc atgttgattc
     2581 attttatttt actaagcagc atattaatgg caaccgctag tgatcccaaa atggggaatg
     2641 cttctttgta cggcttttca tatctcttta ttgtttattc gttacctaaa gattcgttga
     2701 acaagaattt ctttacacaa acaagtagct tattattttt gtttttttgt tggttttcag
     2761 ttctccttta cagaaaacat cgagaaaaga acaaagacaa aagcttgttt aaagagattt
     2821 ttttgaaagg catgtattcg caggaaaaaa tttggatgct catctatgca tttggcatta
     2881 gtcttttgat cgttgcagga gagtatgtcc cttttcagcg attgatgtgg gcagggtttg
     2941 cattttcttc tattgtatct agctatggat tgatgtcgat tggtttcaaa gaacgagcag
     3001 tagaccgaat cattggctca ttgattggat gtgttttatt tattggtatc agccaattta
     3061 ttccttttaa ctgggtcggt atattaggtg gtctagcttt aggtgtttgt tctacctata
     3121 gatataaaac agtttttaat tcttttggtg ctttggcaat cactgccagt ttattcgggg
     3181 ttccaggagc agtaacgatc cgcatttttg agaatatcct tggggtatgt ttaggaatca
     3241 tgtatattgg ggtgactgaa atacttatcc gaaaaataag agaaaaacac ggtttgaatc
     3301 attagatgag atcgaataaa aaataaggaa aaagtgaaga tacacatgga tgataaattg
     3361 ctatcattcc atgtgtatct ttttacggta aatcagtgaa acgttcgact ttcattttta
     3421 atttatactt tttacggagt tcgtttattt gagccatcat ttcggatttg tgatgctttt
     3481 cgattgcttc ttcatctttc caacggtcga tcagtaaaag agattctgga tcttctagtg
     3541 gaaagtaata gtcatatttc tcgtttcctt cttctgcacg aatcgctttg acaatgtttc
     3601 tttcgaccat ttcttctgca aattttctgg cttgtccatt tgtacttgta tacaaaatat
     3661 tcactgtgat actcactaaa tcccctcctg aaaaaattct atcactagta tatcacggtg
     3721 ccagaaatta ttattcaaga tatgatacac attttttccg caatgctacg gaaatatata
     3781 ttttgaatag aaaacgctta caagatatgc ttggtttata aaaataaaag gagtgattga
     3841 tttatgaaaa aagcattgat tatttgtgcg gcaggaatgt catcctcgat gatggcctca
     3901 aagacaacgg atttctttaa gcaaaaaaga gaagaggtac tcgtagatgc agtttcagct
     3961 acagaaggcg ataatatgat taagaatagt gattttgatt tatttctgat cagcccgcaa
     4021 acgacgatgt ttttggataa attcaaaaaa ttaggagaat ctgttggaaa gcctgttgtt
     4081 agtatccctt tccaagcgta tgtcccaatc cctacaggca tccagaagtt agcagaggtg
     4141 atcgaagaga acatatgatg gaataggagt ggatgataat gaaacagaag gaaaaattgc
     4201 tgttgagata tttgattgat cacaagaagg agtatgtcac cagtcaacgt ttagcttctg
     4261 aattgttatt atctgatcgg acaatccgta attacttgca gcggatcaaa gagttagtag
     4321 aaaaaaacgg aggtaagatc attgctaaac caggttatgg ctaccaactg catattttac
     4381 aaagactgac atttgacttg tttttgagtc ggcaagaaat agtacctgga tatgctagag
     4441 aaccgcaagg attttatgag tccgaagatc gacaaaagta tatattgaac caattgcttt
     4501 tggaagatgc cattcttttt atggatgatt tggcagaaga gctttatatc agtcgttcca
     4561 gtttgacaaa ggacatgcaa gaaatcaagg agcgattgat tccatattca ctaaaaatcg
     4621 tttctaagca tggtcaaggg acatggatcg aaggggaaga aagaaatcga cggcatttta
     4681 tcatggatac tttttttgga aaccattatg gaaattcatt gaaagaatat ttagggcaaa
     4741 gccgtttttt cccagacatc agttttgaag agctagtcat tatcattctc gatgaaacaa
     4801 gagaagctaa gttaaaagtt tcggatttta tcatacagaa tctgacttta cacttggctt
     4861 tggggatcaa acggctccga gaagggtttg aaatcaagga attaggcatc gaacaagaag
     4921 tttctaagcg agtagagtat caagtggcgc agcggatcgt tcaacgtatt gaggtaatcg
     4981 caggtgtatc gtttcccgaa gaagaaattg cttatttgac attacatctc atggctaagt
     5041 cgaatcacaa agaaaatcaa aatgatcagg aactatcaaa ggaattagcg aaagttctga
     5101 aaagattgtc tcaggaattt catttttcat tagtagagga tctccagctt ttcaatggac
     5161 tactcgatca tttgtcaccg atgatgattc gattgagccg aggtattcgc attgagaacc
     5221 cattgactga ggagataaag aaagaaaatc ccaaagtctt tgacgcagta aaaaggcatt
     5281 tcagcaacat gccggctttg aaaaactata ccatcaatga agatgaatgg gcctatttgg
     5341 ctttgcatct catggcggca ttggaaaaag aaagagctgc gcataaacta catgcattga
     5401 ttatctgtgc aacgggttac ggcagtgccc aactattaaa gaatcgcgta gtcagtgaat
     5461 tcggtaaaaa tattacagtg gtaagtgtaa aaggctatta tgagatcaat gaaacaactt
     5521 taaaaggaat cgacctgatt atttcttcta ttgatctttc gacaatgttt ttcaaaattc
     5581 cagttttaca tgtcagtatt tttttgaatg aagatgatgt tcgtaaaata cgaaaggtag
     5641 ttggagaatc tataccctat cattcctcag atagaccgat accagcattt tctctacagc
     5701 aaaaaaagca gatttacacc gaacagttgt ctgaaaaatt tttcaagact tatacgtacg
     5761 aaccgaaaaa ggaagaaatt cttcatgatt tgctgcaaaa gctgagcata aatgaagaag
     5821 aaggatatat aagagaaatg cgaaagcaga tccagcaacg tgaaaatatg ggacaaatca
     5881 tattcagtga tacagtggca gtcccacatc ccgctgttcc agttggaatc gaaacaaagg
     5941 tagccgttgc attgattcct tctgggatgc agtgggatca atatcaagaa attcattttg
     6001 tttttttagt ttcgccttct tatgtcgaaa atgaaggaat tacggtcgtg actaaagcaa
     6061 tcgttaggtt agttgaccag ctaaaagtac agcaggaaat cttagctgaa cctatttttg
     6121 agaatttcag cagtaaattt atcaaactga tcgaataagg aggaaaacag atggctgaaa
     6181 aaataaacag tgaaacacta caagtgactt cttttgatat cattttccat agcggaaatg
     6241 cacggacact gatacatgaa gcatttcgct cgatgcgtaa agagatgttt gaagaagtag
     6301 aagagaagtt gcgacaagca aatgaagaga ttcttcatgc gcatcagtca caaactcaac
     6361 ttctgaaaga atatgccagc gggacaaaaa tagaaatgga aattatcatg gtccatgcac
     6421 aagatcatct gatgacgacg atgacattat tggaagttgc acaggaaatg aattatttgt
     6481 atcaaaaaaa taaatagaaa ggaaggatca ttgtgcagga tacagtaaaa aggaaaatcg
     6541 aattagaaaa aaagcaactt agtttgaaaa acatgtattt caatcgttat ctaatcgtac
     6601 gttacctgac tgcctttttc tttttcatga acatgcaatg gatgattctg cttctatcag
     6661 ctaaaagttt aggaagtagt ttaccgatga ttctgatttt agctattttg cctgcagtag
     6721 gagaacaagt aaagctttat cgaaaacacc aaacgaacgt tccatggaca aagtggtatt
     6781 ttttgttcca gagtgtcttt aatttattag tgattccagt gttgtttacc tcaggattta
     6841 cattcttgta tccttttatg gcaaataaca atggaggaca gttatttgtt ttcattcttg
     6901 ttgtaagcgg tatttttgcc agtgcattta tacagtatcg tttaaagaaa atttcactca
     6961 accaagacca acagtatatc cgtattaaac aatatgaaaa agcgttatat ttaggaaagg
     7021 agaataacta atgtttgatt ttttgcagaa atacctgatg ggacctatgg ggaaaattgc
     7081 gcaacttaaa atcgttcggg ctgtcatggc agcggggatg gcttctattc ctttcacgat
     7141 tgtaggctcg atgtttttgg ttttaaatat tttgccatta ccgttcccat ttttagaagg
     7201 attttttaat gcaacttttt tcaaagttag tgacttgtac atgatcgtca atacaatgac
     7261 gatggggatt ttatctattt actttgccat tgtgtttgct tatgaattaa cgtcaattga
     7321 acgagatgaa caaaaattaa atgttaatcc gctcacgggg gcattactat ctgtttttgc
     7381 attctttatg tgtatccctg aattgatcat gactgatggt aaaatcagct tgattgcttc
     7441 tatcaatgag acagaaactg tagtaaatgg tattaggatg ggctcttttg tcgaacgttt
     7501 aggaacttca ggaatcttta cagctattat tatgtcgatt attgcggtcg aattgtattg
     7561 tatgtgtgtc aagagaaatt gggtcataaa aatgccagat gttgttccgc caggagtttc
     7621 tcgttctttc actgctctga tcccaacatt tgtcattgcg tttgtggtga tgatcatcaa
     7681 tggattatta gttgcactag gaacggatat cttcaaaatg attgctatcc catttgggtt
     7741 tgttacgcag ttgacgaata catggcttgg tgtcatggtg atttatttct tgatccatgc
     7801 attgtggatc gtagggatcc atggagcgaa tatcatcact tctttcttga ccccgatcgt
     7861 attagctaat atggcagcta acgcacaagg cgcaaattat ccgttggcag gagaattcaa
     7921 caattcttat gtaaccgttg gtggatcagg tgcgacttta ggattgatca tctttattgc
     7981 attcctcgcg aaatctgatc agctgaaagt gttaggaaaa gcctcacttg taccaggatt
     8041 attcaatatc aatgaaccaa tcattttcgg gatgccaatc gtctacaatc cctatttagc
     8101 ggttccgttt ttcttagctc cgatggcttc tgctacactc gcttattttg ccattcggct
     8161 ggaaatcgtc aaaccgatgc ttgcacagat gccgtggcct tcaccagtcg ggatcggagc
     8221 atttgttggt agtggtggtg attggaaagc tgctgtgtta gcagtcattt gtgcaatcat
     8281 cgcattcatt atctggttcc catttatcaa attctatgat aataaattat taaatgaaga
     8341 aagagaaaag gcagcagaat tagctagtga aaagttaaaa tgatttctaa gaaaaaagga
     8401 actgtgacaa aaaatcacag tccctttttt tcttagaaat gggaaaccac tagtatataa
     8461 ataccattat tcttcaatca accgcttcac gattgcataa tccccttcat aaggttcatc
     8521 tacaccattg attttttgat agggatccac gccttttccc gcaataacga ctgaatcttg
     8581 cggagcgctt tctgctaaag cgcgtcgaat cgcttcagga cgatccattt cataatgaac
     8641 gatcaaatct ggattagtaa ttgcttcatt gatttcttcc gcgatttttt tcggatcttc
     8701 aaatgctggg tcatctgccg tcaaaaaggc gatgtcagct gtttctgata gcacttttcc
     8761 aaaatcatgt cgacgggaga ttgctttgtt tcctgggctg cctaatacaa caattacacg
     8821 gccatctgga tgttcatttt tggcaaattt cagcaatgtt ttcaagctta gataattatg
     8881 tgcatagtcc acatagacat gcgctccatt ggattggatc aattgatcca ttcggcctgg
     8941 tacacgagct tcttttaatc cgtcttgtgc atcttgactg gaggcacctg ttagtgctgc
     9001 ggcaatgatc gcactggctg cattttcttg gttgaatcct ccagccagca aaatatcata
     9061 agcagtatcg cagatagcta agcgatcttc atgagaagat aaagtaaaac cgtgagtacc
     9121 tttatctgaa cggatcactt gataattgct ttcttccgaa cgaccataag tgatcgttgg
     9181 aatctggaat agatcggctg tttccctaag taaatcaaaa tagtcacttt catgatttaa
     9241 aacaactgtt tttgaattca agatcaattg tcgcttgcaa tagaaatagt catcaaatgt
     9301 cggatgttcg atcggactga tatggtcagg cgagatattc aagaagattc cgacatctaa
     9361 agtcaagccg tatacgcgtt gtgttttgta agcttgtgaa gaaacttcca tcactagatg
     9421 agtcatacca ttttcaactg cttctgacat catacgatat aaatctaatg actcaggcgt
     9481 tgtcaaatgg gatttgaaat atgttttgcc atctaacgtt gtattcatag tagaaagcaa
     9541 tgctgttttt ttatttgttg tgtgatccaa gattgctttt gtaaagtacg cagcagttgt
     9601 tttacctttt gttccagtga atccgatcac tttcaattta ttttgcggat agtcgtaaaa
     9661 agccatagca agaagcgcca ttgctttacg gatatccgtt acgatgattc ctactgctga
     9721 attttcgtat ggttgttctg atacataata ttgaataccc tgttcgattg ctgaatccaa
     9781 atattcttct ttgaaattca ttcctttaca gaaaaacaaa gtagaagcat cagcttttct
     9841 tgaatcataa cttaactgaa gaaattcagc tttttctggt acatcaagat gccagcctct
     9901 tgttgaaaca aattctttta atagattttc ttttaatagt aaatgacgga tgtcttctaa
     9961 agagaagctc attgattgat ccctcgcttt attcaatttc ttggtttatt atagcacact
    10021 ctttttaata tatcgtttgt ttccgctatg acaaaatcca gctttattca aattttcttg
    10081 acacagggga caagcggatg agtattttca taaacaatga actgactgta atagatagga
    10141 gaacgaatag tgtctccaac aatccaaaaa cataataatt caaaaagacg ataagactat
    10201 tggtaagtaa aagtccttgc ggcattggaa gccgaaaaaa tttgtggaaa ataatcggcg
    10261 gtatcgttat accgccattt gaggccccga ctgtgtacaa tgtgtaaacc ccaagactga
    10321 acaaaagact tcctgaaatc agtgaaaaga aatgtgagga gatcatttcc acttttggaa
    10381 caatctctaa aacaacagga aaaagcagac ttcccgctac agtcttaaaa aatactgatt
    10441 ttcctaatag gacagcggct agaagcagca tcataagatt gatgctccaa acagtaactg
    10501 agcgttggat agaaaaggcc gtttcaacta aatgtccgat ggcgcccact ccggcggaag
    10561 ctatatcgtg agggagcaag aaccaattca atccaactgt gataaagaaa agacctaaaa
    10621 atataacggg tagttttttt atttcttgtg tcattgatat ctcctataaa tgttagccat
    10681 aaaaggctgt atatttcttt actttaccaa aaaaacgaaa ccgaattcaa aaaaacaatt
    10741 gttcttataa aagttatata aaatcgattg ccagtttctg ttttaccaat taaaatgata
    10801 gtaatgtttt gtagaaagtt ggaatctgac cgatggataa tcaaagaaaa ccagcattag
    10861 atcaattaac accgcaagaa aaaatggcac gaggctctgc ttggatgacc gccagtaata
    10921 tcatttcaag attgctaggc gctgtctata tcattccctg gtatgcttgg atgggcgaaa
    10981 atgctaaggc tgccaatgga ttattcaata tgggatacaa tatatatgca ttgtttctac
    11041 tgatctctac agcaggaata cctgctgcga ttgcaaaaca aactgcacgc tataattcat
    11101 tgaatgaata tggcacttca cgacgattat ttatccgtgc attacagatg atgggcgggt
    11161 taggcctgtt gtttgctttg ttcatgtaca tcgcctctcc ttggctagct catgcttctg
    11221 gtggcggaga agaactgatt ccaacgatgc gttctttgag tatcgctgta ttggtttttc
    11281 cttgtatgag tgtgatacga gggtatttgc aaggcaatca agaaatgatg ccttatgcgc
    11341 tgtcgcagat tgtagaacag gtggcacgta ttttttatat gctattggct acattcatca
    11401 tcatgaaagt catggatggt gactatgtga cggcggtcac gcaatcaact ttcgcggcat
    11461 ttatcggtat gctagcaagt attcttgtcc ttttgtattt tttgaagaaa catcaagcgt
    11521 atacatcggc gtttattcac tacagcgaaa acaaaataaa tattgcaacg aaggaattgt
    11581 tgttagatac cgttaaagaa gcgattccgt ttattattgt gggttcaggg gtaacgatct
    11641 tcaaattagt cgatcagttc acttttatga agatcatgtc tgcatccacc gagtattcca
    11701 atgcacagtt actggatctt ttttcgattt ttagtgccaa tccagataag ttgacgatgg
    11761 tagttattgc attggcaaca tcgatcgcgt ctactgggtt accgttgatt acagaagctg
    11821 ttacgttgaa agatcgagta ggtctggcaa aattgacaag cggaaattta cagttgtttt
    11881 cattttttat gtttccggcg acatttggtg ttatgttact tgcctatccg ctaaatacat
    11941 tattttatac accggattct ctaggaagta atgtactgat ccaagcaagt tttgtaggac
    12001 tcttcctagg actatatatg ctagtttcca acatgctgca aggaatgttt gaaaacaagg
    12061 cggcaattaa ttatttggtt attgggtttc tagtgaaact ccttcttcaa tacccagcca
    12121 ttcgtttatt tgaagtatac ggccctttat tggcgacaat gatcggattt gctgtgtctt
    12181 gtaccttgat cttaaagaga atccatgaag tagcccgctt taaaccaagt tttgtctggc
    12241 gcaggacatt gctgatcttt attcttacct tgattatgct tttggcttcg tggatcacaa
    12301 agatgatttt tggtgctttt ttaaacgaag atagcaaatt ccagtctcta ttgttgattc
    12361 ttgtagtagc aggtataggg gctttagtgt atggttattt agctttgaaa atccgcttgg
    12421 cagaaagact actaggacca ggaatagcgc gtttacgaca taaattaaaa ataaaataag
    12481 tgaatcagaa gagctagatt gatgctcttt tgaaatgggg gaaacgcatg cgtttagata
    12541 agtttttagc agatatggga cttggcagcc gcaaagaagt caaaggatta atcaaaaaag
    12601 gaacgatcga agtcaatgga caagtggtga aaagcgataa agcgcaagta aatgaattcg
    12661 aagatgcggt tacttattta ggagaaatca ttacgtatca aaaagatttt tactacattt
    12721 tgcataaacc tgcaggagtc atttctgcta ctcaggataa tcatgatcaa accgtaatcg
    12781 atttattgga agaccaggat tatcgggaag atctttttcc agtcggccga ttagataaag
    12841 acacagaggg cctcttgatt ttaacgaatg acggggtgtt tgcccatcag ttactatcac
    12901 ctaaaaaaca tgtggagaaa gaatatctag ctgaggttag cggtataatg acagaagaag
    12961 atatccgttt atttgcagaa ggactgatta ttgatggcga tgagcagaca ttgccggcaa
    13021 aactccaaat tgatcaagta gatcaagaga cagaaacttc aattatccgt ctgattttgc
    13081 atgaaggaaa gtttcaccaa gttaagcgaa tggtcaaagc agtaggaaaa gaagtcttat
    13141 atttaaaaag aatccgtatg ggaaaatttt ggctgcctaa agatttgaat aaagggcaat
    13201 atcgacccat gaccaaagaa gagctagaac aagtgagaga aaaataattg aatggatagc
    13261 taaaagaata agcagagtag ttgtagcgcc atctgaaaag cagacttgtc cgtctgactt
    13321 tcggatggct tttttgtgaa atttcggctt atttccgtag aagctacttc tggaacaccg
    13381 tttgttcgga ataagggact gtgacaagac ttttgttaca gtccccattg ttccttgtga
    13441 ctcagagtta gatagtaagg acacgatctc cctaatactc aggccaaaac gctgaattca
    13501 caacctctga taaacggtgt tcaatcagct gaccctcggt attagctcaa aaaacggcaa
    13561 aatatgagga actattttcc cgtttttttc tctaatactc aggccaaaac gctgatttca
    13621 caacctctcc tatactttgt ttcattttcc ctatactttg tttatttatt ctcattattg
    13681 aaagcgctat aattacgttg cgaatgaatc gaaaggggtt tttagatgaa aaaacgaaag
    13741 gggttcaatc atttttttat gaatctatgg cgttataaag cacttgtcct gatggctgta
    13801 ccgggtatgc tttggatgat ttttttcttt tacatacctg taatggcgaa tgtcgtagca
    13861 ttcaaaaatt ttcatatttc agcagatggg ttcttggcta gcttgaggga aagtccttgg
    13921 gtgggttggg aaaatttcaa atttttattt tcttcggatc aagcatttct catcactaaa
    13981 aatacaattt tatataatgt agcatttatc cttttgaatc tgctgatctc agtcgtattt
    14041 gcaatcatta tgagcgagtt gagaaataaa cgactcgtta aagtttatca aacgatgtcc
    14101 ttactacctt attttctatc ttgggtcatt atcagttact ttgtttacgc ttttttaagt
    14161 cctgacaaag gaatattcaa tcagtggatc actggacatg gaggagaagc tgtcaattgg
    14221 tataatgaac cgaaatattg gccgtttatc ttggtgttca ttggtacatg gaaagggatt
    14281 ggttataaca gcattattta ctttgcatct gttatgggaa tcgatccgac ttattatgaa
    14341 gctgctatgg ttgatggagc tagcaaatgg cagcagatca aacatgtgac gataccacaa
    14401 cttattccac taatgacgat tttaacgatt ttagccgtag gaaacatttt ccgagctgat
    14461 tttggcctgt tttataacat tcctaggaat tccggtgcat tatatgatgt gactcaagtt
    14521 ttggatacgt atatctacaa tggcctgaca tccacaggag attttggtat gacggctgct
    14581 gcaggacttt accaatcagt tgtcggcttt gtcttgttga tgatcacaaa tacgatcgcc
    14641 cgacgttttg atagcgattc tgcattattc taaggaggaa aaaaatgaaa aaaaagaaag
    14701 tggagagagt ccaagtccgc tctttcaata agacggctaa ttttttctct aatataatga
    14761 ttgcactctt tgctatttcc tgtattttgc catttatatt tgttatcgcc atctctttta
    14821 ccgatgagtc catattgtcg actcacgggt acagtttttg gccagaaaag ttcagtatat
    14881 ttggttatac gtacttgttc gaccagatgc aggataaaat tttccaagcg cttttcgtca
    14941 ctgtacttgt tactgtttta ggtacactga tcaatagcac ggctacttct ttatatgctt
    15001 atgcgatttc acggtcaaac tttccattcc gtcgtttttt taccgttttt tgtttgatta
    15061 cgatgttgtt ctcaccaggg atggtggcca attatcttgt tatgacaaat cttcttcagt
    15121 taaaagatac gatttgggca ttgatcttgc caatggctgt cagtcccttc aatattattg
    15181 tgatgcgcac attctttaaa cgttcggtct ctgattcgat tattgaatcg gcacggatcg
    15241 atggagctag cgaactgcga atatttgttc agatcgtttt accgttagct gttccaggta
    15301 ttgcgacaat cagtttattt gccgcattgg gttactggaa tgactggttc aatgctttac
    15361 tctacatcca agatgataag ctagttccac tacagtatct tttgatgaaa atccaaagta
    15421 atattcaata tctgacacaa aattcaggag caggaagcca attgacaggc ggattagcct
    15481 cagttccagg agaatctgcc agaatggcga tcgtagtcat ctcgacgttg cctattgcga
    15541 tcagctatcc atttttccag aagcattttg tcaaaggtct aacaatcggc ggagtaaaag
    15601 aataaagaaa caaaaatata aatcataaaa ttaggaggaa gaaaaatgaa gttatggaag
    15661 aaactagcct ttacaggtgt ttcagcgttg ttgttgggaa cattagcagc atgcggaggt
    15721 tctggttcta aagaccaggc agaagctagc aattcggaca ctttgcagat gtatcaaatc
    15781 ggagataaac cagataattt cgatcaattg atggaagtag caaacaaacg aatcgaaaaa
    15841 gagatcggtg taaaagtcaa tatcaattac attggctggg gcgattacga aaagaaaatg
    15901 aacgtcatca tttcttccgg ggaaaattat gatatcgcct ttgcgaacaa ctatgtttcc
    15961 aatgcccaaa aaggagcctt tgctgatttg actgaattag cgcctaagta cgctgaaaaa
    16021 gcttataatg atttagatga agcatatatt aaaggaaatc tggtcaatgg aaaattatat
    16081 gctttcccag tcaatggaaa tgtctttgct caacaagtac ttacttttaa caaagcttta
    16141 ctagataaat acgatctttc aattgatgga atccaatctt acgctgatgc agaaaaagtc
    16201 ttgaaggaat tccatgaaaa agaaccaaac acggcagctt ttgccattgg acaaggcttc
    16261 aaagtccaag ggaactttga ttatccttta gggaatacgt taccatttgc tattgatctg
    16321 gatggagatg attcgaaaat catcaaccaa tacgataatg aaacgtatat cggactgtta
    16381 cgtacaatgc atagctggta caaacaagga ctcattccaa gtgacgctgc aacgagcaat
    16441 aaggattatc cactagaagg aaatacttgg ctaatgcgtg gagaaacaca aggaccgtat
    16501 gattatggcg atacaatttt gacaaatgca gcaaaacaag aacttgtctc aaaagcaatt
    16561 actgttccac taaaatctac agctcaagca caaatggcaa attttgtcgt atcaaatact
    16621 tcaaaaaata aagaaaaatc agtagaactt ctagggctgc ttaacagtga tccagaatta
    16681 ttgaatgggc ttgtttgggg gatcgaggga gaagcatggg aaaaagtcga tggttcagat
    16741 gataaaatca aattgctaga tggttatcag ccaaatacac atatgtctgc ttggaataca
    16801 ggaaacaaca agattctata tacacaagag tctattacgg atgacatgat tgccaaacgt
    16861 gatcaatcga ttgctgatgc agaaacttca ccgattttag gattcagctt caacactgac
    16921 agtgtcaaaa cagaattaag taatatttct aatgtcatga atcaatattt agatggattg
    16981 aatacaggga ctgttgatcc agatgaaaca ttaccgaaat tgaaagacgc tttggacaag
    17041 gctggctatg ataaggtatt gaaagaaatg caaaaacaat atgatgagtt ccgacaagaa
    17101 taataatgaa taaagacaaa ggggttgtga caaaagacgt gtcacaacct cttgttccga
    17161 ataaacggtg ttcaaaagcc agtttctcgg tattaagcta aatatatgta aaaatgtgga
    17221 aagccatatt cacaaaattt ttcttactac tcgaaactaa gcggctattt cacaaactct
    17281 tggtaaacgg tgttcaatca gctgaccctc ggtattcgct cacaaaacga caaaatatga
    17341 ggaactattt ttccgtttgt ttctctaata atcaggtcaa ggtgctgatt gcccaacctt
    17401 tttttgtata atgagaaagt ataaacttaa tgtttggagg agaagatatg ttagggaagg
    17461 ttttggaaga gttatttatc cggatctggg tcattataaa actaaccttg tatttctgga
    17521 tatatacatt tgccggcggg atcatctttg gattaggtgc ggcatggaaa acagtcaatg
    17581 aactatttta tttgtacgga ttcgagtata aagaaatcac aataaaaaga ggctggaata
    17641 tatataaaag aaatttttta agaggcaatc tgctatttag tttattttta tctggtactg
    17701 ctttattgag ttacaattta tatttatctg ttcaaatcaa agggctcatt tttttagcta
    17761 ttgattttat tttacttttt gccttgctct gcctatttgc tacttatcaa tacagtatga
    17821 ttttagatag tgaatatacg atctctgttc ctaatctgct aaagctaagt tttatttcgg
    17881 ttttttccag cttttcgtct tttctaaaaa taattattgg tagcggtata attttaggcg
    17941 tgacttggca attcaaagga ttgatcctgt ttggtgtcat tggtcttttg acggtttgga
    18001 atggtacgat gacaacacat tggcgtgaag aattagataa acagttggaa agttatgaat
    18061 aagtttcgga ttctattttc aaaaggaacc ttactaaatc gtctgttgcg gaaatacgcg
    18121 gttatcatga tcggtgtaac gatgactgct accgttattt ttagtatcca tacttgggaa
    18181 caaaatcaaa aacaggcaga aaacatgaca agtgatgccg ttcaaagcac aagcagaatg
    18241 ctgaatgata aaacaacctt gagtaggatc atcaaaaacc agcttgtagg gaattccgaa
    18301 aagatcgaaa atgtgacgac ctacttaaca aaacccatag atcagtatct gatgtatgta
    18361 tacgaacagc aaaacagtac cgatgaatta gtttctttcc caaatcaaat caaagatctc
    18421 tacgcaaatt atgaagaact aagtgcgata tatatcgtgt tgaatcaact accggagtat
    18481 tatgaatctt ctagagaaaa caaaggtggg gaaataaaaa aggggacacc aaaattacta
    18541 gacgcctttt atatcaagtt gcctatcaca caaggaggag ctgagtcagg aagtattttt
    18601 attggttttc aaaagaaaga actagatatg attttagaaa atctaacgtc attcaatgga
    18661 ctctctttat acatgatttc tggaacgaca aatcgactat acacattcca tgataataaa
    18721 atagctaaag aaacgtttga aagacaagaa atgatcatca cagagagtct gaagaaaaat
    18781 tcacaattgc cgattgacga tctggaaaaa aacaattttg ttcaacacca agaactgtct
    18841 gatgattatc gtatattagc tgtactagat aaaaaaagtg taaaaatcga aacgggaaaa
    18901 aatcttgccc cgctgatcat tggtatcatt attttagaca atatactgct tatctttctt
    18961 tataaaacat tcaaacgata ttcacagcaa gtatctatcg tcatgcaggc catggatcaa
    19021 acagcagcag ggaatttaga gacgcggatc gacataacaa acacggaata tgaactgaag
    19081 gaactttcaa tcggtatcaa cgaaatgttg gatagcatca atcagtttgt agaagacatc
    19141 tacaaattag aaatcaaaca gcaagacgca catatgcggg cgcttcaagc acagatcaat
    19201 ccacactttt tatataatac attagaatat atccgaatgt atgcaatcag cgaaggaagt
    19261 gaagaattag cagatgttgt gtatgcgttt tccgctttgc ttcgaaacaa tacgaatcaa
    19321 gagaaaacga tcactttaaa agaagaactg gacttttgcg aaaaatatgt ctatttgtat
    19381 caaatgcgtt atcctaatcg agtagcctat cattttatga tcgatcctga tttggaaaag
    19441 atcgaagtac ctaaatttgt gatccagcca ttagttgaaa attattttaa acacggtatt
    19501 gattttactc gattcgataa tgcgctaagt gtcaaagtct tgcaggaagg caaacgggta
    19561 aggatcatca tcaaagataa tggaaaaggg atgactgaaa aacggctaaa acagattgaa
    19621 gaaaaactgt ctcatcctaa agtggaactt cacggttcta tcggtctgca aaacgtgaat
    19681 gaacgtttac gtgccagctt cggcagcagt tattatatgt cgcttgagaa taatgagaca
    19741 ggtggactga ccgtttctat tacattcaag gagggatgag cgtgtatcaa gtgttattgg
    19801 tagatgatga atacatgatt ttgaatgggt taaaaaagat aattgattgg caaagtttag
    19861 gctttcaaat agtagcaaca gcagagaatg ccaaagaagg actagctgta cttgaacagc
    19921 gacagattga tttagtagta acggatgtga caatgccaga aataaatgga ctggaattta
    19981 ttgaagcggc tcaaaaagaa cgtcataatt ttgaatttat gattttatca ggataccaag
    20041 aattcgatta tttgaaagga ggtatgcaat taggcgccgt gaattatttg atgaaacccg
    20101 tgaataagtt cgaattggtt gaaagcctca agaaaatcaa aacacggtta gatcagcaaa
    20161 atgaacaaaa aaatcaacaa gaaatctatc aagaactgtt attcagtcaa tggttgaatg
    20221 aagaattgga tgaaataagt gaagaagaaa taataggaca aataagtgag aagcagcata
    20281 ggatagtatt gattcaactg gcaagaactc atgatactct tatcaataga tggttgcaag
    20341 aacggcaaca aatcttttac tatcaacgaa attacggaga ccgtgtattg atcacgttgt
    20401 tgttggaggc agatgaagtt gatggcttct gttgttttgt tcaagaaaac tttcctgatc
    20461 aggaatggct gatcagtatc ggggaagaga cagattcttt ggacaaaatc cctgaaacat
    20521 tccaacaagc gaaagacaat ctacagttgc atcaatttta tggagataaa gacgagcatg
    20581 ttttttacgc agtacaagca gaaacaaaag atcaaaccat cgatttttca agtttcagac
    20641 gcgtgctgca aaataaacaa ttggaagtcg ctcaaaaaat gatcactgat ttttttgaac
    20701 agtttcagtt agcagccatg atgccggaag atatacgata ttccagtttt ttactgttta
    20761 tggagattca acgggaattg attgatctgg aagatgagga atatttacaa ggaatcgaaa
    20821 aaatccatca ggcaaaaacg gtgcaagaac ttcagcagct acttctgtca ttcatcaaaa
    20881 agcatcagag acagaaaaag tacagtgaca atgtggaaaa agtaatcgta atcctgcacc
    20941 agcattatca agaaccactt acactcaaag aagtgtcaga aaacctgcat ttaaatgtca
    21001 tgtatctagg acagctgttc aaaaaagaaa cgaaaaaaag tttttcagct tatttgaacc
    21061 atttacgtat ggaaaaagcg aaacaactgc ttttgcacag taatcaaaac atcaatgaga
    21121 tagcaagtga gattggctac aacaacacca cgtatttctc taaattattc aagaaaatcg
    21181 tcggcagatc ccctaaagag taccgagaaa acagtggaga atcataaaaa aaaagccaat
    21241 gtaatgaaat aacttataaa aaattgtcta gaaatctaat tttgggctgt tcttattact
    21301 tgaggcaagg cagctttttc atgacctctc gataaacgga gttcaaaagc cagtttctcg
    21361 gtattaagcc aaatttatgc aaaaatgtgg aaagccattt tcacaaaatt tttcttaata
    21421 ctcgaaacta aacagctttt tcacgacctc tccactaaat ggtgttcaat cagctgaccc
    21481 tcggtattag ctcaaaaaat ggcaaaatat gaggaactat tttgccattt gtctctctaa
    21541 tactcaggtc agaacgctga tttcacaacc tctcaataaa cggtgttcaa aagcttgcat
    21601 ctgcggtaat aagaccaacc aaacgaaaaa tatgaggatc tatttttgct tggctgttct
    21661 tattacttga tgcaggacag ctttttcaca acctcttgtt aattatagtt tgataaggaa
    21721 aaaggcaaat cttttgcttg atatttctta gggtgaggga tgatccctaa ttggtaagag
    21781 atcgtgccgc ctttcagcaa atcttgatgg gtaaaatata atttcgtata ttctctgtcc
    21841 atccgtttga ttttatggat aaattgttgc tgcggccgat taggcgttgc ttcaatcgtc
    21901 aattcctttc catttgacaa aagcaaaaca gccttgtcaa ttaatggcat accgataaca
    21961 tattcaccgg ttccaggcgt gacaggataa aatcccagac tattgaagat ataccaagcg
    22021 gccatacttc cattgtcctc atctccaggg taacccattg gagaatcgtc gaaggtctga
    22081 gtcatcaact gtttaagcag tggctgtgcc atttcaggtt gtcctatata actgaacaag
    22141 taaggatagt gaaaacttgg ctggtttgaa atagctaatt gtccaaattc tatcgcggcc
    22201 atctcactca tttcgtggat ctcaaaacca tatcctcctg ggtcaaacgt tgggggctga
    22261 ttgcacagct caatgagttt ttctttatat ctctcactgc caccatattt tccgatcagt
    22321 cctgaaaaat cgtgataaac agcaaagctg ctttgccaag cacttccttc tgcataatct
    22381 tgtccccaac gattagctga aaatggttct ctgaacttgc catctttatc ttttgaacgc
    22441 ataaatcctg actcatagtc aaagatattt tgatagttca atgattgctg ctgatatttc
    22501 ttcgtcattt cctcttcttc tagtaccttg gcaacttggc taatacaaaa atcgctataa
    22561 gcatagtcta atgtgtgatt gactgattcg tggtagtgat taggaacata gccatatgtc
    22621 aagtaatctt ctgttccttg gcgtccataa tttggatgtt tgctttgaac cgtagcacct
    22681 ttttccattg ccgttagaaa ttcaggcatc aagtctcgtc ggatatcttt tacagcagca
    22741 tctgcaatga ccgcatcgat caatgtccca ggcataagtc cacgttcatc aggagacagc
    22801 cattttggca aatagccact ttctctatag ctgttcaaaa aaccttccag catttcttcg
    22861 tatttttcta cagcaatcaa agaataaaga ggataaaccg ttttatacgt atcccaaaac
    22921 ccattatttg tatagagaac accaggtttt atagatcgac tagtcgtatc atagtggatt
    22981 ttttgcccac taggatcaat ttcataaaat gtttgtggaa ataaaaacac ccgatataaa
    23041 ttatgataaa acgtccgcaa ttgttgttga tcatggtgtg tgagctgtat acgatcaaaa
    23101 taggactgcc attgttcttg actgtgagca aggtaagtct ctttgctttg gttttgttct
    23161 agttccaggt tataagctgc ttgttccgag ctgataaaag atgtcccaaa tcggatagtt
    23221 tgtttttttg tctgttcaaa atacaacggg atcgagtcgc tatttttgtt ggaaacagct
    23281 aactcatcaa ttgttaaagg atattcaaat ctcaatataa aataaaaaga aaaatcagga
    23341 tcttctgaac cagcaaaatg tgtgattttt ccttccactg tgtaaggatc tataacaaag
    23401 agctgatggc gtcccggaaa ggataaaagt aaaccgctgt catttttgct gtaatcaata
    23461 gataagattc cgccatacat gctaggtatc aatgtagaac agatgccata acgtaattga
    23521 cagatcgaca gatgagtcgg gcaaaatata ctttcttctg ggcggtaaga actttgagca
    23581 tggaaaaggg tgttctcctg tagttttcca ttgatcggcg taaacagcat atgactgaaa
    23641 tcacccatcc aaggacttgg ttgatgggta agacggtagc cttgaaaaac gcggtcatca
    23701 ggatgaaacc accagctgcc gttttgatcc gtagtttgcg gtgcaaaata attcatccca
    23761 aaaggaacgc cagtataagg ctggcagttc ccattagaga aatttggctg attcgctgtt
    23821 gcatgtctag tatctatttg accgatattc attttatttc tcctttgttg attgtctttt
    23881 gatgaatgaa actggaaatt tactatcgga tggtcgatct tttgtctcta accaagtgac
    23941 caaagcatct cccgcaagct tacctaactg ttcaaaatct tgtgcgatgg ttgtcagtgg
    24001 cgggtcaaca agagctgctg cttggatatc atcaaatccg ataattgaaa aatcttcagg
    24061 gatatgataa ccatgctgtc tcaagagatt catggtctgg atagcgacaa catcgttttc
    24121 acaaacaaaa gcagttactt catacttagt gatataagaa agcaattcat ctaatgtcgc
    24181 gcttttgtca tccagtgaag tgtggaaagt caaaccagct ttgtccaatg cttcaaggta
    24241 accaaggtaa cgctgtcgaa cggattgtgg atgagtctgc gtaccaaaca aataagcgat
    24301 ttttgaatgt ccctgttcga tcaaataaga ggcagcaagc gcaccgcctt ggaaattatc
    24361 ggaaagaacg gtaggaaaag gtaactcata gattttttta tctaatatga cgacagggaa
    24421 ttctttcaat gaaagctcaa aaagtaagtc aagatgttgt tctgtatcaa gagcataata
    24481 aatcaatccg tcaaattcat tgattagctc ttttgctgtt ttattttgta gaaagtcaag
    24541 cgtcgtcatc atgacatcaa tctgtttatc ttgcatcaca gggttcaatc ccttgctaaa
    24601 atcaccaaca gacaaatcag cgacatatgg aagaagaaac agaatccgtc gtgtttttgt
    24661 aggagaagca agaatctgtt ccggagaagc ggatttaacg aaactgcctt tcccgcgaac
    24721 gcgataaata agtcctaatt gctctaattc agtcaatgca cgtttggaag tgattctgct
    24781 tactttatag gtacgtgaaa gttctttttc agttggtagt tggctgtcta caggtaattc
    24841 accagttaaa atagccgttt gcaaatcatt aaatattgtc tggtacaatg gttgagtcat
    24901 ataaacacct cttaatgata tatcatattc aaataatacc ataatggatg aaaaagtaaa
    24961 taaaaagata ttttttgaaa gcgtagacat aattggctgt atgaagtata atctttaaag
    25021 atatatcaaa tagaaagaag gttttattag tggtttataa agatatacca aaatcggtgc
    25081 agaaatttat ggaagatatc acacaaaaat gtggggatat ccatgcggac tgggcaaaga
    25141 attttacagc agcatttgcc aatactctgt tgacaacagt caaaaagcaa aatgacggaa
    25201 ccaccttttt attgacggga gacattccag cgatgtggtt aagagactct actgcacaag
    25261 ttcgtcctta tttagtgatt gcaaaagaag atgaggaatt agctgacatg atcagcgggt
    25321 tagtcaaaaa gcaatttttt tatatcaata tcgatccata tgcgaatgcc ttcaacgaag
    25381 aagctaacgg tgctggccac caaacagatc atacaaaaat gaacgattgg atctgggaaa
    25441 gaaaatatga aattgattct ttatgctacc caatacagtt ggcctatctt ctttacaaaa
    25501 atacaggaaa aactgatcaa ttcaatcaat cttttattga aggtatcaaa aaaatcttgg
    25561 acgtgttcaa aacagagcaa gatcatgaac actctcctta tacatttgta cgagacacga
    25621 caagaaaaga agatacgctg atcaatgacg ggcgaggtgc aaaaacagct tttacaggaa
    25681 tgacatggtc tggtttccgt cctagcgatg atgcttgccg ttatggatat ctggtaccat
    25741 ccaatatgtt tgcggtggtc gtgttaggtt atgtggaaga aatttttcaa acgatactcg
    25801 atgataaaga aattgtacag caaacacaga aattgaagaa agagatccaa gaggggattc
    25861 agaatcacgg acgaacggtt aatcaaaaag ggcaaacgat ttatgcatat gaagtagatg
    25921 gaatgggaaa cgccacagtc atggatgaca gtaatgtgcc caatctgatc gccgcacctt
    25981 acttgggata ttgttctgaa caagaggaag attatctgca aacaagaaga acattgttga
    26041 gtaaagaaaa tccatatttc tatgaaggaa agtacgcaaa aggaattgga tcctcccata
    26101 cgccagaaaa atacgtttgg ccgattgcat tagctatgga aggaatgaca acgtcagaca
    26161 aatctgaaaa agagcggata ttgaatttac ttgtagcaac tgacgcagga acacacctta
    26221 tgcacgaagg attcgatgtg aacaatcctg aaaattatac gagagaatgg ttttcttggg
    26281 caaatatgat gttttgcgaa ttagtcatgg attactttga tattagagta gaaaagtagg
    26341 aggtatcgta aatgaaaaag aaagtatata tcatttctca tagccactgg gatcgtgaat
    26401 ggtacatggc ttacgaacag catcacatgc gactgattga attgatagac gatctactag
    26461 agctatttga agttgatccg tccttcaaca gttttcattt ggatgggcaa acgattattt
    26521 tagatgacta tcttcaagta aggccagaaa aaagacaggc aatccaacaa gcaatcaatg
    26581 aaggaaaatt gagaattgga ccattttata tcttgcaaga tgattttctt atcagctcgg
    26641 aatcgaacgt gagaaatatg ctgattggca tggaagaaag ccgtaaatgg ggaacccctg
    26701 tcatgttagg ctattttccc gatacatttg gaaatatggg acagacgcct caattaatga
    26761 aacaagctgg tatttcagca gcagcgtttg gccgtggtgt aaaaccaatt ggctttgata
    26821 atcaagtttt ggaagcagaa aactattctt cccaatactc agagatgtgg tggaaaggcc
    26881 ctgatcaaac agcaatcttt ggtctgctat ttgccaattg gtatagcaac gggaatgaga
    26941 ttccagtaga aaaagaagca gctcttgcct tttggaagca aaaattagcg gatgcagaac
    27001 aatatgcctc tacgaaccac ttattgatga tgaatggtgt tgatcatcaa ccggtacaaa
    27061 aagatatatc aaaagcaatc catctcgcaa atgaactgtt tccagattac gagtttattc
    27121 attctaattt tactgactat ctggaagcag ttcaaaaaga tgtgccagaa gacttaggct
    27181 cagtagaagg agaattgaca agtcaagaaa cggatggctg gtatacttta gccaatacag
    27241 catctgctcg ggtttactta aaacaatgga ataccaaggt ccagcgacag ctagaaaata
    27301 ttacagaacc acttgcgacg atggcttatg aagttagtgg aaactatccc catgatcaat
    27361 tagattatgc ttggaagaca ttaatgcaaa atcatcctca cgacagtatt tgcggttgtt
    27421 cagtcgattc tgtccatcgg gaaatgatac ctcgttttga aaaagcagat gaagttggaa
    27481 agtatcttgc acaagattcc ttagaacagc tgaccgcagc aatcgatacg accggattcc
    27541 caaaagacag ctttccattt gtcattgtaa atactgcagg aatggataaa actggtgaag
    27601 cagaaataac catcgaatta gaaagaaaaa gattcgctga aggaatacct gaacaactat
    27661 atcaagagtt agaaaatttg cctaaacgta agtatcatgt agaaacaaaa agtggggcca
    27721 ctataccagc tattttatct gaagaaactg tccaatttgg ttatgatttg ccgaaagacc
    27781 gtttccgtgt gccatatatg gcaagaatga tcaaagtgac tttaccatta gaaaacatgc
    27841 cagcattttc ttgggaaaca ttcgcgcttg tagaagggga agcgaaagca gaagaaaagg
    27901 aaacaatgat tcatcagagt ggacgaatca tcgaaaacgg ccctctacat ttgacgattg
    27961 aaaaaaatgg taccattaca atggaagatc gcaaaaacaa acgaaagttg aataatctgc
    28021 atatttttga agatatcggc gatataggaa atgagtatat ctttaaacaa cctttctgtg
    28081 atcagccaat cctatccagt aacaaagaaa actctgaagt aaaagtatta gtagatacac
    28141 cggaaatagc aaaaataagt attctacagg aaatggaaat ccctgtttct gcagacgagc
    28201 gtttagaaaa agaacagcag atggttgtgg aatttcgtta tcgaaaagca gaacgatcca
    28261 aagaaaaacg aatccttcaa ataaaaacaa tcatgacaat cagaaaagat agtaaaaaaa
    28321 tcgactttga aacgactctc gacaatcaga tgaaagatca tcgcttacgt gtcttgtttc
    28381 ctacaaagtt acatgtggaa catcacgaag cagatagtat ttttgaagtg gtgaagcgcc
    28441 caaaccatgt gtctaaaagt tgggaaaacc ccacgaatcc gcaacatcag caagcatttg
    28501 tcaatattca tgatgaagag tacggtgtaa cagtcggaaa ctttggtttg aatgaatatg
    28561 aagtaacaga agacggacaa atcgcagtga cgctacttcg cagtgtggga gaactaggcg
    28621 attggggata ttttccaaca ccagaagcac agtgtctagg tgagcatcgg ttcaattaca
    28681 gcattgaact acatggacca gaagaaaaat tctctactta tttgcatgca tacgcagcac
    28741 agattccttt ttccactcaa caaatcaaac atcatgaagg aacattgatt tcaaaacaac
    28801 aatatttaac gataaaaagt gaaacgtttg caattacagc tttgaaacgc agcaagttta
    28861 gtgataaagt agtagtaaga ggtttcaata tgtctagtca tttagaaaaa ttggaaataa
    28921 ctaaagacaa tggaaaaact gtcatattga atctgcttga agaaccaacg aagcaagcgg
    28981 ttgtcccaat aatccaacct tatgagattc ggacaatcgg attcgaggag gaaaacgaat
    29041 gtatggcgga atagaagcag gcggaacaaa atttgtgtgt gcggtttcag atggtggaga
    29101 aattttagaa aaattaagta tccctaccac aacaccagaa gaaacattgg atcaggtatt
    29161 tgaatttttt gatcgttatg aattgaaggg aatcgggatt ggctcattcg gcccgattgg
    29221 tatcgacaaa acaaaagata attacggata cgttttggca actcccaaaa aagggtgggc
    29281 acaattcgat tttcttggca caatcaagga acgctacaat attcctgctg cttggacaac
    29341 ggatgtcaat gctgctgcat atggggaatt gaagcaagga gcagcacaag gaaaaaatag
    29401 ttgtatttac cttaccgtgg gaacaggaat cggtgcaggt gtcgtgatca atgaagaaat
    29461 tttttcaggg atcgcacatc ctgaaatggg acatatttgg gtgaaacgcc atccagatga
    29521 ccattatgaa ggtacttgtc cttatcataa agattgttta gaaggattag cagcaggacc
    29581 gtctattgag gcacgcacag ggatcaaagg gcaagatctg ccgcaagatc atcctgtttg
    29641 ggctattcag gcttattata ttgctcaagc actgatcaac tatacgttga cgttagcacc
    29701 tgaaaagatt attttaggcg gtggggtaat gaatcaggat catctccttc aaaaaatccg
    29761 tcagcaattt gttgaattga tgggtggtta tatggaaaca cctcaagtaa gtgaatatat
    29821 cgttcgttgg ggactgccga atgaaagtgg gattatcggt agtttgctgt tagcagaaca
    29881 cgaacatcaa aagtaagcag acaaattaca caaaaagaac agagtcttat cattatctgc
    29941 tgataagact ctgttctttt ttatttctat tcccataatc caggtaaagc tttaccgact
    30001 attttttctt gagtaaatgg atggatcatg tgcagttcta atgcatggag catcagtcgt
    30061 tcagctgttc tattttggta gagagggtct ccaacgatcg gatgtccctt atgagctaaa
    30121 tgaactctga tctggtgtgt acgtccggtt tccaaaacac aatagacttg tgtttgttca
    30181 gaaagtactt tgttgacagt gacatgtgtc aaggcgctct gaccattttt atcatctacg
    30241 accctttttc tccgatcatg gcgatctcgt ccaattttat tggtgatggt catatctttg
    30301 gcaatttctc cccatacgat ggcttgatat ctccgataga tcattttttg ttccaacatt
    30361 cttccaagta tcggcaagac aaatggattt tttgcaaata aaacggcacc gcttgtttct
    30421 ttgtccaagc ggtggacaac gtaaggtcgt tgctgtttag tgtcgagata agcagctaaa
    30481 tgattgagta aggtactgtt ttctgtcggt tcatttggat gagtcttcat tcctgcaggc
    30541 ttatccacta taatcaaatg ctcatcttca tataaaacac ggatgtgctt cgcatctcct
    30601 aattgaactt cttgataatt ataatctgtt tcttcgaata acaatgtgat ctggtcattg
    30661 ccctttactt catgatggaa caaagcaggt tgttgattga tccaaacgtt tttacgtata
    30721 cgcaaaaagt gtcgaacctt tctaggaact aaccattcct tttcaagcaa gtcgcgaatt
    30781 gttgtttcag gatggttcat aggtaaagtg atcgtgattt tcacaagtgt actcctttca
    30841 gtgcaattgc agactaattg taccattttt aaaacatatt taagaaaaaa cttacatttt
    30901 tctgttcatt cttatgttac tctacttgca ctaacgtaaa aaaacatatt gaactacaac
    30961 ttaagcagga agaaaacact ctttcactat ggtaaaataa gacgattgaa tcaaatagac
    31021 aggagaagaa gcaaatggat tttcaaagca ttttagaaaa gataaaagct gctttgatca
    31081 gtttttggcg ttggatcaga ccatatctcg gacaattcca tcgatggcga aagcgcatct
    31141 ggaaaaaata tcatgtgaac aaattgattt tgctgattgg tttgatctgt gtcttagtga
    31201 caagtatcta cctctttatt ttagcaaaac aagcaaatgt cgaaacgtta aaatcaggat
    31261 taagccaatc gacagtcatt tatgataaga aaaacgaaga agctggcaca ctgtacgccc
    31321 aaaaaggaac atatgtagaa ttaaacgcga tttctcccta tatccaagat gcagtaatct
    31381 cgacagaaga taggaatttt tacgagcatc acgggtttga tatcaaaggg attgcccgtg
    31441 cagcagtccg aatggtcttg tctggcggaa catcaggggg cggaggaagt acgatcactc
    31501 agcagcttgc caaaaatgcg tatctgacat tagaccaaac gtttgatcga aaagcgaagg
    31561 aattattttt ggcaatcgag atcgaaaaga agtacagcaa agaagaaatc ttgaccatgt
    31621 atcttaacaa tgcctatttt ggcaacgggg tatggggtgt ccaagacgct tccagaaagt
    31681 attttggagt agatgcaacg aatgttacgc tgtctgaggc tgctactttg gcaggaatgc
    31741 tgaaaggtcc tggtatttat aatccgatcg atcacccaaa aaatgcgaat gatcggaaaa
    31801 acacagtact aagtgtaatg gaagaaaacg gaaaaatcac aaaagaacaa gaacaagcag
    31861 aaagccagac agatatcagc gcgtatctta atgacacata cgataattca gattctggtt
    31921 atcgttatcc ttattatttt gatgcagtga tcgatgaagc agttaacgag tatggtcttg
    31981 atgaagaaga tgtcatgaat aaaggctata aaatctatac agctttagat caggattatc
    32041 aaaagcaatt agaagctact tatcaaaaca gtgcattatt cccagcaaat gcttcagatg
    32101 gtgccatggt ccaatctgct tcagtagctt tagatccgaa tacaggtggt gtacaagcac
    32161 tagtaggacg aagaggagat catgtcttta gaggattcag ctttgctaca cagatgcgtc
    32221 gttcaccagg atcaacgatc aaaccattaa gcgtatatac accagcactg gaagctggat
    32281 acaagccttc cagtatcttg aaagacgaac cgcaaagtta ttacgatgcg cataattttg
    32341 acgggacata ccaaggagaa gtaccgatgt atcaagctgt tgcacaaagt ttgaatttgc
    32401 ctgctgtatg gcttttgcat gagatcggtt tacaaaaagg atatgataaa gcagaagaat
    32461 tcggcctgcc tttagcaaaa tctgataagt attatggctt agcccttggt ggactggaaa
    32521 aaggagtatc tccattgatc atggcgggtg cttacagtgc atttgccaat gatggtcaga
    32581 tgtatacgcc gcatcttatc acgaaaatcg ttgattcgac tggagcggtg atcgtcgata
    32641 acacaaacaa aaaaccaaaa caggtcatat caaaggaaac agccgatgaa atgaccagca
    32701 tgcttcttgg tacattttca aatggaacag cggctgctgc gaatcctgca ggttatacga
    32761 tagcagggaa aacaggaacc acagaaacta atttcgatgc cacaaaagca aatgaccaat
    32821 ggatgatcgg ttacacgcca gacgtagtga tttcgacatg gatgggttac gaagaatcca
    32881 gcaagctgca ctatttggaa gggacaagtg gaaatgttgt cgggaaagtc ttcaaatcag
    32941 cggcagaagg catccttccg tatacttcaa aaacaggatt tagtgtagca gatgcctatg
    33001 ccacaggagg acaagtggta gctgcagatc aagttggaaa cacaggaaat tctaatggag
    33061 agtctggaaa ttggcaagat aacttgaatc aatatggtga acaagcaaaa gaagggctga
    33121 aaaacttcgg cgatatggtg aaagaaggcg ttcagggaat tggtgaagcg gctaaagacc
    33181 tctggcggaa atatcaagga gagtagcccc tttgaaaacg aataacccca tgttacaata
    33241 gagagtaact actaaaagaa aagagggcat aacatgtcaa acatctacga tagcgcgaat
    33301 caaatcgaac gtgagatccg tgaattacca gaattcaaag cgttgaaaga agcgtacgag
    33361 aaagtacaag caaacgaaga agcacacaaa ctgttcaaag acttccaagc gatgcaaatc
    33421 gaattacaag aaaaacaaat gagtggacaa gagttcagcg acgaagatgc aatgaaagca
    33481 caagaaatgg ctgtgaaaat ccaatcagaa gaagtaatca atgacttgat gcaaaaagag
    33541 caaggcttca gtacaatcat caatgacttg aaccgtatca tcatgacacc agttcgcgac
    33601 ctttacagcg aataaaacta ttttatgaaa caacagaggg tgtgaaagag acgttcggcc
    33661 ttgagcgatg acaaaattgc ttcttattgc cgataggctg tctcttgaac accatttacc
    33721 aagaggtcgt gagcctaccg tttaactctg agttacaagg aacaatttca aaaaacagct
    33781 tctcatgttt gatgactatt gtgacttgtg accgaggagt tggcaggaga acaccgttta
    33841 ttcagaaata ggagctacga caaaagtctt gtcatagctc ctattttttg tcattcattt
    33901 ttcaagcggt agaaatagcc tttttgagct aacagttttt cgtaagtacc tatttcaacg
    33961 atttttcctt catcgatcac aacgatttta tctgcctctt tgatcgttga aagccgatga
    34021 gccacaataa aagtagtggg tgtttctgtc aggtaattca gggcttgctg gatttttttc
    34081 tctgactggt tatctaaagc tgaggttgct tcatctagca aaatgatttt tggctgacgt
    34141 atcaacgctc gtgcaatgga gatacattgc ttttggccac cagacagctt gttgccatgt
    34201 tcgcctacta aggtatccag accatcagga agctggtcaa tcagtgaaga aagttgcgca
    34261 gcttcgatga cttcatctaa acgttctttt gatacgtttt tcaagccata agtgatgttc
    34321 tctttgatcg aagcggagaa caacaaagtg gtttgaggaa caacggctaa ataatttcgc
    34381 acacttcgca tatccagttc atccaaaggc tgatcatcta gaaaaatttt tcctgaagtc
    34441 ggctggataa atccaatcaa taagttaagg agtgtagatt ttccagagcc agatggccca
    34501 acaaaagcaa ttgtttctcc agctttcacc tctagagaaa aatgatcgat aatcggtttg
    34561 agtgagtccg gataaagaaa agaaacatcc tcaaaacgaa aatttccatc caaatgttgg
    34621 atttttttct taccgtgata agtttctaca tcgccagcaa tcaacagttc gccaatagaa
    34681 gtgatagatt ccatgccttt tgaaatcgta ggaatcagcg tgatcattcc agaaacggaa
    34741 ttgacgatcg tcgtgaaata cgtctgatac atcacgacat cgccgggttg gatgcgccct
    34801 tgtaaagcta atatcccagt gaaactcaaa caaatcagct gaaatatctg aaaactagcc
    34861 cagctgactg atccgaaaac agattgcagg atatctaagt ggaatccttt ttcatagatt
    34921 tgagtaaaat gcttatttaa gcgagttgtt tcgtgttttt ctaacccatg agctcgagca
    34981 atcggtgcta attcgatcac ttcgatcact tttgcagaag tctcttccat ttcttgcctg
    35041 aagtctgagt tggactgtct gatcctttta cggaaaaaga gagtaacgaa tgcggcgaga
    35101 ggaacagtca ataagaaaaa catgaaaaca acaggacttt tataaagcgt gatacctaaa
    35161 gctacgaata aattgacagc gatatttaat ccgctgacaa atacttgaga ggacaacgtt
    35221 tggatagctt ctacatcacg gatgatcttt gactggattc gtccagattg caattctttt
    35281 tgataaggaa tagatagttc ttggattttc ttgataaggg tcgctcttag tccagcttct
    35341 acttgacgga tcgaagtgct atggtatttt acatgaaaat aattcgtcaa tatattttga
    35401 ccaatcagac aagccatcaa aaaagcgttg aaataaatgg cctgcaactg agaagaatct
    35461 ttcgatgaag ctgcattgat tacattggca atagcgatcg gcattaacca agatggaaga
    35521 tgtttgataa taaaaaagag tcctgacatg gcaaaacgcc aataatttcc ctgataaaga
    35581 tgcagcaatg tctgaaaagc atttgcatga tatttttgat aacttttctg tattcgttcc
    35641 tccataatct tctccttaac aatcttggta aataaactgc aagtgttcta ttgcttcagg
    35701 aacataaatc tcaggagtag cttcaagagt ggcgtacatt agaggacgct catatttgat
    35761 ataatgcagt accgggcgga aatctaaaca gcccttgcca acaggtacca tgcggatctt
    35821 tccattttcc atgatatagt ctttgagatg aagcgctgta atataaccat gtaaattgtc
    35881 caaggcacct cggatcactt tttcctgatc agcatgattt tctttatgca tcaaattcgc
    35941 acaatctaaa atgattttta aatttggtga agctacttca tcgattaaac gtttagctaa
    36001 ctgatagtta tagattggat gattgatccc tgcttcaaca gcaacagtta cgccaaaatt
    36061 ttctgcatga gcgactaatt caatgataga atttctggcg atctgataag cttcttcagt
    36121 aaaattttct tttgtgtaac cgacagagac actaccggtt tccgtagcaa tcatcttggc
    36181 ttgataggca gagcacagag caatttgctg tttgaaagtt gccaatgctt gtgcacgaac
    36241 ttcttgattt ttgctggata ggttgatata gcatcctaaa atggaaagtt cgatattgtt
    36301 tttttggaag tattcaccaa aataggcagc actcccaagt gtcatgtcag ttaatttaag
    36361 ttgttcagga aatgcttttt gtggtgcaaa ttggatatgg gacaagtgaa gctgtgatac
    36421 tttttgaacg atttcttcac gatttcgaac atctaaatcg tgggcacgga tgcctaaatt
    36481 taatggaaac atctcaaact cctttttgta aataattagc aagaggcaga cgggattctt
    36541 ttatcaattc aacaattatt cgggcaactt tatcagcgcc ttctggacta aagtgggtat
    36601 tgtcttttag tccttctggg taatttttac aagtatcagg cataagatgc aggtagaatt
    36661 tttttgtctc ttcttttgag aaggtctgga acaattcttg tgatcttgag aacacatcta
    36721 aaagaggaat atggtgtttc tcagcaaatg cacgcatcgc ttttggatag tctccaagta
    36781 tatctggatt caatgttccg ttttctaagt aatctcgtcg cgtcacagat gtcagtaaga
    36841 ccatttggac gttcgctttt tttgcgcatt caaaaaatat ctgcagattt tttaaatagc
    36901 taccgaaggg aagcgtacct ctttcttctt ggattttctg gtcgttatgt ccaaattgta
    36961 caaataagaa atcattcggc tgaaactgtg aagctagacg ggctaacctt ccttcctgga
    37021 taaatgattt ggtgctgcgt ccattctttg cttggttatt gatctggatc tcgggtgaaa
    37081 aataagcaga gattttttct ccccaacctg tctcgggacg cttgttttca tctttttctg
    37141 ccgcagtaga atcaccggca atatggatag taggcatgtt atctcttctt tcataaaggt
    37201 ttataggcaa tgaagcagaa cagcaagaga agaagacgga gcaa
//
LOCUS       DAFLWQ010000021        36569 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.022, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000021 DAFLWQ010000000
VERSION     DAFLWQ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.022"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(26..1522)
                     /gene="lysS"
                     /locus_tag="L1V16_001047"
     CDS             complement(26..1522)
                     /gene="lysS"
                     /locus_tag="L1V16_001047"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBN1275402.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="L1V16_001048"
     CDS             complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="L1V16_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBN1275403.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVDCREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="L1V16_001049"
     CDS             complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="L1V16_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBN1275404.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="L1V16_001050"
     CDS             complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="L1V16_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBN1275405.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="L1V16_001051"
     CDS             complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="L1V16_001051"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBN1275406.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="L1V16_001052"
     CDS             complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="L1V16_001052"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBN1275407.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8053..8523)
                     /locus_tag="L1V16_001053"
     CDS             complement(8053..8523)
                     /locus_tag="L1V16_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HBN1275408.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8569..8994)
                     /locus_tag="L1V16_001054"
     CDS             complement(8569..8994)
                     /locus_tag="L1V16_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBN1275409.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9061..9330)
                     /locus_tag="L1V16_001055"
     CDS             complement(9061..9330)
                     /locus_tag="L1V16_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBN1275410.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9341..10936)
                     /locus_tag="L1V16_001056"
     CDS             complement(9341..10936)
                     /locus_tag="L1V16_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1275411.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="L1V16_001057"
     CDS             complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="L1V16_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBN1275412.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14489..15049)
                     /locus_tag="L1V16_001058"
     CDS             complement(14489..15049)
                     /locus_tag="L1V16_001058"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBN1275413.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15402..16376
                     /locus_tag="L1V16_001059"
     CDS             15402..16376
                     /locus_tag="L1V16_001059"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBN1275414.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16546..17946
                     /locus_tag="L1V16_001060"
     CDS             16546..17946
                     /locus_tag="L1V16_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBN1275415.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18024..18746)
                     /locus_tag="L1V16_001061"
     CDS             complement(18024..18746)
                     /locus_tag="L1V16_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1275416.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18825..19331)
                     /locus_tag="L1V16_001062"
     CDS             complement(18825..19331)
                     /locus_tag="L1V16_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBN1275417.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19454..21253
                     /locus_tag="L1V16_001063"
     CDS             19454..21253
                     /locus_tag="L1V16_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBN1275418.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21321..22895)
                     /locus_tag="L1V16_001064"
     CDS             complement(21321..22895)
                     /locus_tag="L1V16_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBN1275419.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="L1V16_001065"
     CDS             complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="L1V16_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBN1275420.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="L1V16_001066"
     CDS             complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="L1V16_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBN1275421.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24672..25310)
                     /locus_tag="L1V16_001067"
     CDS             complement(24672..25310)
                     /locus_tag="L1V16_001067"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBN1275422.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25311..25961)
                     /locus_tag="L1V16_001068"
     CDS             complement(25311..25961)
                     /locus_tag="L1V16_001068"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBN1275423.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="L1V16_001069"
     CDS             complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="L1V16_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBN1275424.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="L1V16_001070"
     CDS             complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="L1V16_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBN1275425.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29104..29844)
                     /locus_tag="L1V16_001071"
     CDS             complement(29104..29844)
                     /locus_tag="L1V16_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBN1275426.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="L1V16_001072"
     CDS             complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="L1V16_001072"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBN1275427.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31215..32153)
                     /locus_tag="L1V16_001073"
     CDS             complement(31215..32153)
                     /locus_tag="L1V16_001073"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBN1275428.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32146..32637)
                     /gene="def"
                     /locus_tag="L1V16_001074"
     CDS             complement(32146..32637)
                     /gene="def"
                     /locus_tag="L1V16_001074"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBN1275429.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32652..35060)
                     /gene="priA"
                     /locus_tag="L1V16_001075"
     CDS             complement(32652..35060)
                     /gene="priA"
                     /locus_tag="L1V16_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBN1275430.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35313..35618)
                     /locus_tag="L1V16_001076"
     CDS             complement(35313..35618)
                     /locus_tag="L1V16_001076"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBN1275431.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="L1V16_001077"
     CDS             complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="L1V16_001077"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBN1275432.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT         9886 a         7989 c         6705 g        11989 t
ORIGIN      
        1 aattccttag acagctttta ttcgattatc tcattgttgg gaatagcaaa acatcccgaa
       61 ttgattgtgc atcagttagc aacattacta atctgtcgat cccgatgcct agaccaccag
      121 ttggcggcat accgtattct aaggcttcca agaagtcttc gtctacaccg tgagcttcgt
      181 catttcctag ttcacgttct ttttcttgcg cttcgaatct ttctctttga tcaattggat
      241 cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac tatgaatagt tcgaatcgat
      301 ctgtgaatcg aggatcttct ggatttttct tcgctaaagg cgaaacttcg actggatgtc
      361 cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa tgtttcaaag aattcattga
      421 taacatgtcc gacacccata gcttcggtta cttctacatt gtgtttttcg gctaaagcta
      481 atgcttcttc caatgtcatt tcttgccaga agtctacacc agtttgttct ttgattgcat
      541 ctaccatatg gatgcgttta aagtcacttt ctaagtcgac agcttgtcca tcatatgtga
      601 tttttgctgt tcctagtact ttttcagctg cgttacggat aataccttct gtcagattca
      661 ttacatcatt gaaatcagta tatgctgtgt atgcttctaa catcgtaaat tctggattat
      721 gtgtagtatc aattccttca ttacggaaaa cgcggccgat ttcataaact ttttccattc
      781 cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat acgcaaatat aaatcaatgt
      841 ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc tccacctgcc tcattgtgca
      901 atactggtgt ttctacttca atatagccat tgccatctaa atagcgacgg atttcgctga
      961 taatttggct tcgtttcata aatcggtcaa agctttcgcg attactgatt aaatccaagt
     1021 agcgttgtct gtagcgttgt tcaatattcg ttaagccatg gtatttatct ggcagtggac
     1081 gaagtgcttt tgacaaaatc gtgatttctg aagctttgat agaaacttcg cctgtgtctg
     1141 ttttcatgat ttgtccagtt acaccaaaga aatctccaag gtctgcatgt ttgaatactt
     1201 cataggcctc atcacctact tggtcttttc ttacataaat ttgaatttgg ccttcacgat
     1261 cttgtagatg cgcaaatcca gttttccctt ttcctcggcg agtcatcata cgaccagcta
     1321 cactagcggt caatcccatt tctgctagtt cttcttttgt tcttggatca aatagttcat
     1381 gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc aaatggatcg attccatctt
     1441 cacgcaattg ttccattttt tgacgacgta caagcatttg atcatttaaa tcttctactt
     1501 gatgttgttg ttcctgtgtc acaaaagttc ctccattctc atgttaatct ctttcctata
     1561 atgccaatga aacacaaaaa aagcaagccg aacttggaat ttcggcttga aaattcacga
     1621 aaaacttaga aatcacaacg tttgtttcaa tagtactttt tccgcttttt ctacaaattg
     1681 atccagcagg tcattgattt cttgctgttt ttctgtctga ttgattgcta ctttcacttt
     1741 cgctgctcga ggaatccctt ttaaataata agccgcatgt gttctgaatt ctctacaatc
     1801 tactttttct cctttgagat ctgctaagcg ttgtaaatga agtttagctg tagcaatttt
     1861 ttcggctggt gttggttcag gaatcagttc tcctgtttcg agataatgct gtgtgcggtg
     1921 aatcatccat ggattgccca gcgctgcacg accaatcatc acaccgtctg caccgacata
     1981 gtcaagcatc cattttgcat cttctggcgt tttgacatcc ccgttcccca taaatgggat
     2041 cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc gcttttcctt catacatctg
     2101 aacccgtgta cgtccatgca tagcgatggc acttgctcca gctgattgtg ctgctaatgc
     2161 attttctaca gcaaagacgt gctcttcatc ccaaccaata cgcatcttga ttgttactgg
     2221 gatatttact gctgaagaaa cagcttggac catttcgtat actttctcag gatctaaaag
     2281 ccattttgct cctgcttctg ctttgattac tttatttact ggacagccca tattgatatc
     2341 tattatatcg gcagctgtgt tttcttcgac aaattgagca gcttcaacta gactatcttt
     2401 atttccgcca aatatctgta aacttaatgg atgttctgtt tcttcaatgt ggagcatctc
     2461 taaagttttt ttgtttctga aatgaatacc ttggtcactg atcatttcac atacgactaa
     2521 gcccgcacca aattctttga cagtgactcg aaatgctgaa tttgttattc cagccatcgg
     2581 tgcaacaacg acacgattag ggatttccac attgccaatt ttccatgtgt gttccactta
     2641 aatccctcct aaggcttctt tcttcaatcc atctaattct tcttcgctat acttgtattt
     2701 gttattacag aaagaacaaa ccgcttctgc accgtgatct tcgtctatca ttgcttggat
     2761 ttcttctgca cctaacgcga taattgcttc tgcaaatttt tcttttgaac agtcacattt
     2821 gaattgaaca ggcatttttt ccaaaatgtt caattcttct gtaccaagca atcctttcaa
     2881 tatttcttct ggtgtctgtc cttcatctaa gagggtagag attcttggtg tcgtttttaa
     2941 ttgttcttcg atcttgctga ttgtttcttc atcggcacct ggcatgattt ggatcatgaa
     3001 tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat acactcagtc caacagctga
     3061 agggatttgt tctgagatag caagatagta agtaaaatct tcagcgattt ctccagaaac
     3121 aatcggcgtt tgcccagaaa aaggttcttt taatcctaag tcttttgtga cagtaaacat
     3181 tccttgtgtt ccaactgctc cccgcacatc gattttacct tcactattta gaggaagact
     3241 gagatgcgga tttttgatgt aacctttcac atctcccttt ccatttgcat ctactacaat
     3301 tcctgttgct ggaccatcgc cttggattcg aacagttagt ttgtcttctc ctttgagcgt
     3361 cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa gcagctgagg aggtgtgcca
     3421 agtatcatga cgtctttgtg cctccgctac ggtatttgtt gcttgaacgg cgtatgctcg
     3481 gacgaatccg tcgtgagcaa gtgccttaac caaataatct ttcatttgtt atgtactcct
     3541 ttttccgttt ttaaactcat agtgaatcat actagcaact actgcttttt tcaactttgg
     3601 aatgcttctt ttaaaaataa ttcagaatca tctagaaaac aggacatcac cctatttaca
     3661 acttaaataa agaaatctcc cgaaaaccgg tttttgttcc ggttttcggg agtcatatca
     3721 gatcaattga cctatatttt tttatttgta ttgatcgtct gaatgattat cttctgattg
     3781 ttgagaatct gaatcatgtt ctgctttatt ttcctcattc agttcatgtt ttgcttcttc
     3841 aaaatcacgt ttttcttccg cttgtttttc agcgtctttt tcttccaaag cacgttttgc
     3901 ttcttcaaaa gttttcgctt ctttttcgct tggataatca tttgactcag taccttcagg
     3961 catcacaccg tgttcaaaca atgacttgat tgctttggca tccaatgttt cgaattccaa
     4021 aagtttttca gcaatcagtt tatgctgtgc acgatgagct tcgatgattt ctcgagcttt
     4081 atcatgagct tccatcaaga tttttcgtac ttcttgatca atctcgaaag cgacttgttc
     4141 cgagtaagct tttgtttgac catagtcgcg gccaacaaac acttgatggt ttccttcata
     4201 ttgaacagga cctaaacgat cactcattcc atattctgtt accatgcttc gtgctagagc
     4261 tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg acattgaaga tgatttcttc
     4321 agctgtacgt ccaccaagta agcctacgat ttgttcaaac atatcttctt tcgtcatcaa
     4381 gaactgatct tcttttggta aagcgatcat atatccgccg gcgcgtccgc gagggatgat
     4441 cgttactttg tggacgaccc gagcgcgact caatactaat ccgacaatcg tatgaccagc
     4501 ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt acgcgatctt ttttagctgg
     4561 acctgcaatc acgcgatctt ccgcttcatc gatatcagaa gcatcgattt tctttttatt
     4621 tcttctagca gctactaacg ctgcttcatt caagacattt tctaaatctg ctccggcaaa
     4681 acctggtgtc tgttgagcca caactttcaa gtcaacgtca tctgccatcg gtttattccg
     4741 tgcatggact cgcaagattg cttcacgacc ttttacatct ggacgtccaa ctaaaatctg
     4801 gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt acatcagaac ggttggttgc
     4861 agcaatgacg attactcctt catttccgtc gaagccatcc atttctacaa gcaattggtt
     4921 caatgtttgt tcgcgttcat catgtccgcc gcccataccg gcaccacgtt gacgacctac
     4981 cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt ttcttcgctg tttcaaacaa
     5041 atcacgaaca cgacttgctc caacaccgac aaacatttct acgaaatcag aacccgagat
     5101 cgagtaaaac ggtactccag cttctccggc aacagctttt gctaataagg ttttacctgt
     5161 tcctggaggt ccttctaaaa gtacacctgc cgggatacgg gcacctaatt caacaaatcg
     5221 gcgaggatct ttcagaaatt caacaacttc aactagttct tgtttttctt cttccgcacc
     5281 cgctacatca gaaaaacgta cgcgattagc ttttttgtct gcttctttgg cttttgattt
     5341 accaaagttc atgacacggc cgccaccgcc accgccgccg ccttgttgtc ccatcatcat
     5401 gtaaaagaaa aagatgatga ttacgattgg caagaagcta agcaataggg aaacccatat
     5461 accgctgctt gattcttctt ttactgttgt agcaactttg ttttcttttg ccagttctgt
     5521 tacttggctc aatgttgtat catttggcaa aatgattgtt gtgaaatggg tagtagtcgt
     5581 atctgttgaa cctaagatag ctaacccacc gctgttagcg acggtctgct gttctttgta
     5641 ttcaccagtg atcttatata caccatttgc aggctgcact tcaaattctt tgatcttgcc
     5701 tgcttgtagt tgttctgtga attttgagta ctcgatatct gacgatcgct ggccgttatt
     5761 accaaaaatg aaataaacga ccattaccat cgctaagatt acgaggacat aatacaaggc
     5821 atttttcatc atgccgttgt tctttttgtt catagttgcc ctccctaagc gtcaatttaa
     5881 tttaacagtt ttttatcaat cctgaccatt ctattgtacc ataatttaat tgagatacag
     5941 cattaatttg attgataaac actaggtttc aatacaccga tgtacggaag gttacgatat
     6001 gcttctgcat aatccaagcc ataaccgacc acaaattcat ttggtacgtt gaagccaaca
     6061 taatctgctt cgatatttac tactcttcct tcaggtttgt caagtagtgt aacaattttg
     6121 actgattttg ctttgcggta tttgaaaaga tccactaaat aagcaagtgt tcttccgctg
     6181 tcaatgatat cttcaacgat caacagatcg cgaccttcta cattcgtatc taagtctttg
     6241 acgattttta cttcccctga cgagactgtt gcattcccgt agcttgaaac atccatgaaa
     6301 tccaattcca aatacgtatc gatagaacga acgatatctg ccatgaatgg taccgctcct
     6361 tttaagacac ctactactag gggattggtg ttttggtaaa tttctgttaa ctctttgcct
     6421 agttctttgc aacgaacttg tatctcttct tgtgagatca aaattctctc aatatccttt
     6481 tccaacatca ggttctcctt ccaattgctt ctttttgata tttgtaaaga agtatgtagt
     6541 gtattttatc agtttcttca cgaatactca aatatgaaaa ggcaaaaggt atcaagctat
     6601 atatatttct tttggcatct gtaatgatcc aagcatgctg cctttgtgaa ttaggtactt
     6661 tctgatcgat aaaatatcta gatacttttt ttgtgagatt ctctgttaat ttaatgcggt
     6721 ctcctgcttt tcttttttcg acatacagtt gcacatcagc aggaatccaa atgtcatgag
     6781 aaaatagaga ccatgaatct gttgctttga tgtcccctgc attttcaggt ttgaccagac
     6841 caatccattc tgtttcattc aaatatattc cttgttctgg aatcagcaac aagcgctggt
     6901 cttctgtctg gctagttgct tgtttttctt ttttagagag tacaacaaaa tgatactctc
     6961 ttttcagtat ccaattattg ccaatactga gttgccattg gctttttttc tgttgccact
     7021 ggtctaaaat cgactccatt tgttgttctt tcaaaataat tcctgttttt gagaatgctt
     7081 tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc tgtcatttct tcaatcattt
     7141 ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc cttttcgatc aactgtccca
     7201 tatatttttg aatgacttgg tctgcccatt ggatctgttg cgaaaattgc tggaaatgtc
     7261 tcaacgcctg tgtattttct tgtttcaatt gaggaactac caaatgacga agccgatttc
     7321 tctggatatc taacaattgg tttgtctgat cctcaaagta aacaagctgc gattccgctg
     7381 cataagtata taggtcttct ttgctaaaac tcagcaacgg acgaatcagt ctgcccgtag
     7441 caaatggttg tacttctttg attccagaaa aagtatttaa ctgtccccca cgaacgattt
     7501 tcattaacac cgtctcgatt tgatcatctc cgtgatgagc agtcatcaac gtgtcatatt
     7561 gtccttcttc catcacgcga gtgaattctt gataacgaaa gttacgagct tctgtttcta
     7621 tggcggattt ggctggatct tcccaaatac ttacatataa agggagattc ttctcttcac
     7681 aatatgagcg aagataggca gcttcttctg ctgattcttc tcttaattgg tgattgatgt
     7741 ggacgatacc taaagaaaaa ccgatttggc gttgcacttg taaaagtaaa tggagcaaaa
     7801 ccatcgaatc aacaccacct gataccgctg ctaaaattct cgatccttgt tgccagaatc
     7861 cttgttcatt cccgtgccga ataaatgact gctgtaatag cggtgctttt ttcccgcctt
     7921 tttcaacgtt catcctttcc acaccctttc ttcctaaaaa aaagagagcg ggaaaacgtc
     7981 taaaacgaca attaacctgc cctctgttga tactatgacc caaatagtcg cactatcatt
     8041 atttgcggct ttttagctgc gacgtccgcc acggccaccg cgctttcctt ctgtgtttcg
     8101 cttcaatgaa gataagcggt catcgctatc tttcaaaaat gaactcatca atgaatcgaa
     8161 gtcttctttt tgagctgaag gttgactgcg agaaaaagat tttttctgtg ctggacgatt
     8221 tcggttgtca cggggatctt tttgttgata ttttttagga cggctttctt ctccagattc
     8281 agcaggttgt tcctgcgctt tccggataga tagtccgatt tttccatcat catttactga
     8341 aataacttta actgttactt catctcctac acttaaaaca tcatggatgt cttttacata
     8401 gccatttgac acttcgctaa tatgaactag acccgttttt ccagcaccta gatcaataaa
     8461 cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt tttgctccta cctcgattga
     8521 cataaaaaaa atgttcctcc taattatttc ccttttttat attcctgctt attttgcagt
     8581 tgtagaacta gttgattgat ctgtttcatt tgtcgagctg tctgtatttg attctaatat
     8641 aggataaact ttttcaccgt cttttgagta aaagaatttg cttctggcaa gtttagctac
     8701 atactcatca tctttcagca atgaaacatc ttggtgcagc tgatcaacgt ctgcgttgac
     8761 ttctttcatt tcagtatttg cttcgactct caattcgttc aattgatgca tcctttgcat
     8821 gtcatggaaa atctgcacac ctattatcgc gaaaatgacc aaagcaccaa caaaaattgc
     8881 agccagtctg cgtcttcgaa aaatcagttg acgttgttgt tgctgaaatt cagcatactt
     8941 tttctttgca tattccgtat ctagcgcagc gattttattg ctttttttcg tcacttggat
     9001 tcgctccaat ctttttgatt gtctttttca ttataccaat atcgtgaaag cttgtctaat
     9061 ctatttctct agtgtttctg tgcgattttc agaaataatt tcgtacattt tttgtgcatc
     9121 ttcttttttg gttgattcat gtaattccgt aattttcact tccaacgttt tgttgccaaa
     9181 ctggactttc aaaatatcgc ctactttgac atcactggaa gatttcgcca atttaccgtt
     9241 gatttgaatt cttcctttat cagctacttc ttttgctact gatcgtcttt tgatgattcg
     9301 ggaaattttt aaaaatttat ctaatcgcat atcttattcc tcacttttta atttttttat
     9361 ttaatcgcag gattttctta ccaaaaggca acattagcca ttctcgtact gtaaacagac
     9421 gaagacgaat cactgcataa atgaacacag aagccccgat cccaactcct atcacgctga
     9481 caaaaaaagc agtggaacga tgagttacag gaccaaatac tatattcaat acaccataat
     9541 acagcagcag tactactgtc atacaaagaa ggctgaacat caacttccgt ccaaaatgcc
     9601 gttctttcca aaaagcattt agctcttttg tttcaattcg aacaaaatac caaagcgtca
     9661 cacctaatcc taaaagggta gacaggcttg cacctgctgt tcctaataaa ccggtcagaa
     9721 aagaagtagt caatcctttt accaatagtc cccatcctgc gccttttaaa gaagggcgaa
     9781 acgagttctt gctttgagca atactttgat aagcttggat gactgcagtg aaagcaatgg
     9841 aaaaaacaaa taatacaagc gctgcatttc ccgcataatc tttaaacaac gcataattga
     9901 tataagggag cagcaaggct aatcccaaag acgcagctaa tgctaaagcg gtcgtcaatc
     9961 taagatagat tttggctgtc tgtaaaaact gacgatagat ccggttggtc aaatgacgag
    10021 tcaacgcagg caggaatgtc gcacttaatg cagtggcaat cactaaacct aattgtacta
    10081 aaggctgacc tcgatcatag accccttttg ctatcttcgc accgtattct gacagtccgt
    10141 aaacttccaa agcatttttt acaaagaaag agtcgatcag ctggaaaaag ataagcaatc
    10201 cactataaat cgaaaccagt ccgccttcta ccagaaaacg ccggatcaag ggctttgacg
    10261 gctgtttgaa caatggaaac cgtcggaagc ttaacgctcc tccatgaatc ttttgttcat
    10321 agtagtgaag gatcccatat gcgcataaac cgccaaaaac agctccactc attgctgccg
    10381 tccctgtttg gtacaccgtc catccaagct ttctaaaagc aaacgcacta cagacaatca
    10441 caaaaacacg aacgaactgc tcaactactt gagaaacagc agttggttcc atcaagaatc
    10501 ttccttggaa attccctcga taaaaagata gaccaggcat cagcaaaaag gtaaaggaaa
    10561 ctacttggat cagcggtttc aattgtatgt ctcccatcat ccaagcaatc cagctgctaa
    10621 atgcaaagac aaacaaccac aaaaagacac ctgtccaaaa tactaaggga taaagatttt
    10681 gcaaagcttg ctttcgctcg aaaggattct ttctttctgc aacgtacttt gatatgaact
    10741 gcggaagacc ggataaagct aaagtcattg ctatcccata aattggataa acttgctgat
    10801 aaacataaaa accttcgtcg ccgactaagt tttggagggg aattcggtaa agggcactta
    10861 atacttttgc tatgaaagaa gcaatcgtca atacaaatgc tccttgcatg acgcgccgca
    10921 tttctttatg atccaaatca ttgctccttc ctacgctgac agatattttt gctcacgcaa
    10981 cgctttgaca aacttttgga tttcctgaag ccatactgct tcttccattt ggttggggat
    11041 cgtcaagcgt atcaccatct gttctttttc aacgcctaga ctggctttta gttttgtcgc
    11101 tgtcagtgct tcgaataact gttccacact atagcgtttt gttccaactt tacttagagt
    11161 aaagactata tgcgcctcct gtttccttat cgtttctagg agcgctcgat cgccatccat
    11221 tttgatctgc ccaattgtca agagatgtgc tacttcttct ggatattctc caaaacggtc
    11281 gagcagatca tcttctagtt catctagcat ttcttgcgaa tcaagttcac gaattcgttt
    11341 atagatctcg attttctgcc gttgatctgc cacgtatgtt tcaggtagat acgcatcgac
    11401 accgaggtcg atctcaacag tggtcttctc cacttgacta ttctttcctt gtttacgaga
    11461 aacagcttcg cttagcattt gagaatacat atcgaaaccg actgcatcaa taaatccatg
    11521 ctgctgagca cctaagagat tacctgcacc gcgaatggaa agatcccgca tcgcaatctt
    11581 gaatccagat cccagttctg taaaatcttt gattgcctga agacgttttt cactgacttc
    11641 gttaaggatc ttctgctgct catacataaa gtaagcatat gcgacacggc tgcttcttcc
    11701 tacccgccct cgcaattggt ataacgtgga taatcccata taatcagcgt tctcaacgaa
    11761 caacgtattt gcgttcggga tatctactcc tgtttcaatg atggttgtag tgacaagaac
    11821 atcatattga ccttcaataa attcaaaaag cgtattttct aattgcgcct ctgtcatttg
    11881 cccatgagca taaccgatcc gtgcttccgg aacgagttct tggatttctt ctactttttg
    11941 ttcgatcgtt tctacccgat tatataaata gaatacttgt ccacctcgtc ccatttctcg
    12001 atggattgct tcgcgaatag ccccaggatt tttttccata acatacgttt ggatcggata
    12061 acgattcgca ggcggtgttt cgattactga aagatcccgc acgcctaaca tcgacatatg
    12121 caaagttctc ggaatcggtg ttgcagtcag agtcaaaaca tccacttgtg cacgtaactg
    12181 tttcaatcgt tccttatgtt ttacaccaaa acgttgttct tcgtcaatga tcagtagacc
    12241 caaatcgcta aattcaatat cttttgacaa aattcggtgg gttcctacaa caatatcaac
    12301 ttgacctgta cgcagttgtt cgatggtttc tttttgttgc tttcttgttc tgaaacgact
    12361 taatagcccg atatttacgg ggaaaccttc aaatctttcc agcatcgttt catagtgctg
    12421 ctgtgccaag atcgttgttg gaactaaaaa ggctacttgt ttgctttcct ttatcgcttt
    12481 aaaggccgct cgaagcgcta cttctgtttt cccataacca acatcaccta cgagtagtcg
    12541 atccattggt ttttcttttt ccatatcccg tttgatctcc gctgcacttc tcaactggtc
    12601 atcagtttca gagtagggga aggcattttc gaattctttt tggtaggcgt catcaggtcc
    12661 aaaagcatat cctttttctg actctcttgc ggcatataat ttgattagat cgtcagcgat
    12721 atcctcgatt tttgaagaga cttttcgctt ggttttcgtc cattcacttc cgcctagctt
    12781 attgatgcga ggcgctttgg cttcagaggc gacatatttt tggatcagat tcagttgagt
    12841 aacaggaata aacagtttgt cgtcgttttg atacaaaata gtcatatagt cttggtgaac
    12901 gccatctact tctagcgttt ccatcccaat gtatttcccg ataccatgat tggcatggac
    12961 aacgtaatct cctgctttta actcattata gcttttcaat cgctctgcgt ttgttactgt
    13021 ttgacgtctc gtttgttttt tcgtcgtttt ttggaaaatt tctttttctg tgatagctac
    13081 tattttttct tgaggaagtt caaaaccagc ctgcaaagct ccttcaacta attgtacctg
    13141 tcctctgatc aatgcatttt tttctgtttc tactactaat atgtcttcat ctcgaagcat
    13201 ttgttctgct ttgcgtattc tgtcctttgt cggaataaag atcacaacag tctgtttttg
    13261 cttgcgccaa cggtccattt ctgttttcag caatggcatt tgtccgaaga actgttgcat
    13321 cgtccgatat tgaaaattat ggattgcttg gaaacgaaga tttcccatcc ctttttggaa
    13381 gagtgagaaa aaggttgtgg tgaacttttc cttctgcacg attttttgta tatctgctga
    13441 aaatgtctgc tcagaaaaca cccgcaattc gctgattttt tgagtctgcc attctgccgc
    13501 ttccctttcg atttcccgat ttgtttccat gattcgctga taatcatcaa cgactagtaa
    13561 actatttgaa gggaaataat ccaagatcgt cacagattct tggtaaagaa gatctgagta
    13621 gaattttgct tcttctgtcg ggacacctgc ttgccagctt gaagtcagct gaccgaagta
    13681 atcttgcaaa aactcgcggt ctgcttcttc tgtggtcgca gcaagccgtt tttctagcat
    13741 tttttgcatt tgctctattc catgttctag atcctctggt ccgtagactt gttcactcgt
    13801 tggggaaacc cagatttctt ccgttttttc gattgagcgt tgtgtttctg cttcaaaata
    13861 ccgcatagaa tctatctcta catcaaatag ttctacacga acaggatagg ttgtcgttaa
    13921 cgggtaaata tcgataatgc ttcctcgaat actgaattct cccggttttg cgaccatctc
    13981 ttctcgtaca tagcccatca aagtcaattg gcgaggaaga ttttccacgt ctatctcatc
    14041 accaatatgc caattcaatt gcgcctgtag ccaagttttc ttattcggca gtcgtttgtg
    14101 caaagatgcg actggcaaca aatagatacc tgcttttttt tcttgaagtg cgttaagcgt
    14161 tgcaactctc tcgcctcgcg cttctggaga agaaaaggcc atttcagcag aaagcacttc
    14221 atccactgga aataaatgga tctgatcttg cggaatcaca tgttgcagat cttctgctaa
    14281 ctgattcgca taatacaaat ttggcatcag aataatcatg tttttatttg ttttcttaaa
    14341 cgctcgagca aatagaagtg ttttcgctga gcccgctaat cctgtgatta gttgtctagg
    14401 cattttttct tctaaattgc tgacccattc ttttacttgc ggatcttttc cgactaattg
    14461 aataatatcc attccttttc ctccttcctc aattgaatcg attcatcgca tccacgaacg
    14521 aatgcccttc tatgagatat tcgactgctt taacagattg acacatgctt tcttctatca
    14581 aaggctgatt ttctttgctg aaaggactaa gcacatgctg gactactgtt tttttccctt
    14641 ctggcctgcc gattcccacc ttgattcgat caaagacatt cgtattcaaa tgggaaataa
    14701 tacttttgat accgttatgc ccgccggcac ttcccttttg acggagccgg atttttccca
    14761 ctgccagatc caaatcatcg tagattacga ctaattcctc tggataaatc ccaaaataag
    14821 tcattagtgg gccgactgca cgaccagatt cattcatgaa tgtttgtggt ttgactaaaa
    14881 ggatcttttc tccattatga aaaaattcgg caacttctgc ttcgaacgga ttttttttga
    14941 aagtagcttg atgctcgcgt gcaattttat ccacgaccat aaagccgata ttgtgttttg
    15001 tatattggta tttggtacct gggtttccta acccgacgat cattttcatt tttgttttcc
    15061 acctaattct aaaaagcagc acaaaaggct ggactgctaa ttagcggtcc agtccatcga
    15121 gcttttttct tttttatact tgtcaatgca tagtataaca caaaacaagg cgtttcggct
    15181 aaaagagaat cgttaataaa tgataaagaa attaaaaatt tcttcaaagt ttaatgaaat
    15241 aattgatata taaaaatagt gaaataacgc acatgtaagc ttttacatat aatacaacct
    15301 tgttatctgt tatattttat agccaaatag cgtgacatgg ggcttgagaa atgttagcat
    15361 aagcatggga aaaaacaaat caatggaagg attgatacta aatgactgca gctgcagaaa
    15421 aaaaagatca tcaaaaagtt attcttgttg gagacggcgc cgtaggttct agctatgcct
    15481 ttgctctagt tactcaaaat atcgctcaag aagtaggtat tgtggatatc aatactgcta
    15541 aaactgaagg agacgcaatt gacttgtctc acgctttggc atttacttca cctaaaaaaa
    15601 tctattctgc tacttacgca gacgcacatg atgctgactt agttgttatt acagctggcg
    15661 caccacaaaa accaggtgaa actcgtttag acttagtaaa caaaaaccta aaaatcaacc
    15721 gcgatgttgt cacacaaatc gttgaatcag gatttaacgg tatcttttta gttgccgcta
    15781 acccagtaga tattttgact tactcaactt ggaaattctc aggtttccct aaagaacgcg
    15841 taatcggttc aggtacctct cttgactcag ctcgtttccg tcaagcactt gcggaattag
    15901 ttgacgttga tgcacgtaac gtccatgctt acatcttagg tgaacacgga gattcagaat
    15961 tcccagtttg gtcacatgca aatgttgccg gcttgcaaat ctatgaatgg gtaaaaaaca
    16021 acccagaaat cgatgaagaa gctatggtta acctattctt tggcgtacgt gacgctgctt
    16081 acacaattat cgagaaaaaa ggcgctactt tctatggtat cgcagtagca ttagcacgta
    16141 tcactcgtgc catcttagat gatgaaaatg ctgttcttcc tttatcagta ttcatgaatg
    16201 gcgaatatgg attgaacgac atctacattg gtgcacctgc tgttatcaac cgtcaaggta
    16261 tccaaaaagt aatcgaaatt cctttaagtg acagcgagca agaccgtatg gctgcttctg
    16321 ctaagcaatt aaaagaaatt ctagatgaag cttttgctaa actagacgct gaataatctt
    16381 tgaacatgac ggaaaacatc tattcggtgt tttccgtttt tttattttat cacccttatg
    16441 gtttctaaat tttttcataa agtagagata accttcgtct tttcctctaa attatgctat
    16501 catgagaccg ttccacccta aacttttact taaggagttg tcgatatgac aagatcttcg
    16561 catcgaaaaa aatcgaaaca tgttgctttg ctttcagttc ttggtgttct cttagtgctg
    16621 atcagctttt atacctatcg cagtacatac tacacaaagc attttttgcc gaatacagaa
    16681 ataaatggaa taaatgtcag caatctaaca gtcgaaaaag caaatgaaaa attaaaagaa
    16741 gcttattctg ataaaaaact ggctattaaa gaagatggaa aagtctggca ggaagtacca
    16801 aaatccgagc tcggctacaa agatgatttc acttcggagc tttctccgat cctaaatgaa
    16861 caaaacggat ggacttgggg aatgacttat gtctcagcgg cagaaaaaca agaaatagat
    16921 cctgtcagtc aaaaccacca aaaactagac actaccgttc agacattgac aactaagctg
    16981 actgatttga acaaagaccg gacacctact actgatgcaa cgatcgaaaa agcaggtgac
    17041 tctttcgtta tcaagcctga agtcaatgga aatacgatcg acgtcgatgc tgcggtcaaa
    17101 caattaaaaa gtgcggtaaa ctctggtaaa gatacaattg aattgactga attcaaagaa
    17161 aaaccaaaag taacatctga agacagctca ctgaaagaac aactcgcatc catgaatgct
    17221 atcgcaaatg taaaagctac ttacagtata aacggtgaga ctttccagat cccatcaagt
    17281 gatattatga gttggctgac ctacaatgat ggaaaagtcg atttagatac agaacaagta
    17341 cgtcaatatg taacagattt aggcacaaag tataacacaa gtacgaatga cacaaaattt
    17401 aaaagtacaa aaagaggaga agttacggtc ccagttggca cttacagttg gacgatccaa
    17461 acagacagtg agacagaagc attgaaaaaa gcgattctgg caggccaaga ttttactcgt
    17521 tcacccattg tgcaaggtgg cacaaccgct gatcatccat tgatcgaaga tacgtatatc
    17581 gaagttgatc tggagaacca gcatatgtgg tattacaaag acggaaaagt ggcccttgaa
    17641 acagatatcg tttccggaaa gccaactaca cctacacctg ctggagtctt ctatgtttgg
    17701 aataaagaag aagatgcaac tttaaaagga acaaatgacg atggaacacc ttacgagagt
    17761 ccggtaaact actggatgcc gattgactgg acaggtgttg gtatccacga ttcagactgg
    17821 caacctgaat acggtggaga cttatggaaa acccgcggtt cacacggctg catcaacacc
    17881 ccaccaagtg taatgaagga attattcggg atggtcgaaa aaggaacgcc tgtattggtc
    17941 ttctaacaaa aataatatat aaaaagaaag cacccgtacg attggtacag gtgctttctt
    18001 tttattatct aacaatgtgc tacttacatt tcagcagcag taaagacttc tgaaacatca
    18061 tcatcgtctt ctagcttatc tactagacgt tccaattgct ctttttgttc ctcatttaaa
    18121 tcaatcgtcg tttgtggaat catcgtcaat tctgcttgcg ccaaagtgaa ctctttttcc
    18181 aactcatctc gtacagcagc aaaatcttct ggtgcagtat aaatctcgaa tacttcagga
    18241 gaagtttgca gatcttctgc ccccgcctct aatacatcct caaacatcgt ctcttcatca
    18301 acagtcaacc catcgcgttc aatagcgata tatcctttgc ggtcaaacaa gtaactgact
    18361 gaacccgttt ctcccagtga tccaccgttt cgagtaaaag ctactcggac atttgtcgct
    18421 gtccgattac ggttatctgt caatgcatgg actaagattc ctactccacc cggaccatat
    18481 ccttcatacg tgatttcatc gtaattcgtt tcatctacgg cactcgtagc ctttttaatc
    18541 gcccgttcca cattgtcgtt aggcatattt gcagcttttg ctttgtccac aacaagccgc
    18601 aaagctggat tcatagatgg atcaggaccg cctgctttag ctgccatata aatttcacga
    18661 gaaagtttct gaaagacttt ccctcgtttt gcatcttggg cattttttct tccttggata
    18721 ttatgccatt tactatgtcc tgacatgatt tttcctccct tgttcttttg agaatacact
    18781 tctattctag tactatttca caaaaaaaca aagccacagc caatctataa acgcttcttg
    18841 aatgccgcaa aaagcacaca taatatcaca gcagtcagag caccgatcga atccaacatg
    18901 acatcttgga acataggtgt tcgtccaccg gtcatcatct gatggaattc gtccaaacct
    18961 gcgtaccctg ttgctgaaag ccaagcaagg atcgctgtca gccaccaaat ttttagcttg
    19021 gggaaaacac ctaaaaacaa gctgcctccc aaaataaaat aggtaccgaa atgtgcgccc
    19081 ttccttaaaa agaactctaa aaatttggcg tagcccagat ggtcgatact caccatactt
    19141 ccaccataat taaaacgtat acccgctaat gtgtctttaa atggctgatt aggcagccag
    19201 ctttctaatc gcgaaacttg tgattgctgt ccgtaagttt gagaagaact gtaaaataag
    19261 attataacga ctatcagtgc gattactaaa taaatatttc cgtttttcat ttgttttttt
    19321 gaagaattca taagtcacct ctgtatttta tcttagactt tttttgaaga aacaacaatc
    19381 attttcatag agacttcttc cataaaaaag tgctatactt aattttgtat tacaatatga
    19441 agggagtttt ttcatgagtt attcattaaa ttggaatcta gattctattt tttccggagg
    19501 cagtcattct gatgctttga accaacggat gaagcaattg gaagaccaaa tgaacgagta
    19561 ttatcaccgc gtaacaaaat ggtcacctag ttctgacaat gcagagcagt taaacgctat
    19621 tcttcaattg caagaaacga ttacgaatgg ttttacccaa tgcagcagct atattactgc
    19681 attgctttct gccaatgtca atgattcaga tgcaaaggtc ttatcaggca agctttacgc
    19741 aatgctgcct cgtctgcaat cagccgaaac tgtattgtca aagaaatttg cagaaatatc
    19801 tgacaatgat tggaatcaga tgctttctca atcttcgttt gaaacaattg cttttcgttt
    19861 aaacgagatt cgtcgtgatg gctcacaatt attatcagaa gctgaagaaa acattataaa
    19921 tacgctttct ttagatggtc taaatgcttg gagcagtcat tatgatacga ttgtagccag
    19981 catttcgatt cccttcgaac aagatggaca agtagtcgaa ttatctgctg gacaagcctt
    20041 caataagatg atgggcgatc cagatccaaa agtcagagaa acacttttcg cagcatggga
    20101 agaagcctgg aaagaaaagg cacccctctt cacggatact ttgaatcatt tagatggttt
    20161 tagactttct gactatgaac ttcatggtgt cacagatttt ctacaaaaac cattagagta
    20221 caatcggttg aagaaagaaa cattgtctgt catgtgggat acaatccaga aaaacaaaca
    20281 accccttgtt aattacttga ctagaaaagc taatcttttc ggtaaagaaa aaatggaatg
    20341 gcaagatcaa gatgcaccta ttattttagg cgatttgaaa gaaaaaacct ttagttttga
    20401 cgaagcagca gcatttatta tcgaaaactt taacaaattc agtccaaaaa tggctaaatt
    20461 tgcccaatct gcttttgaaa agagctggat cgaagcagaa gatcgtcctg ggaaacgtcc
    20521 tggtggttat tgtactgagt taccagaaac aaaagaatca aggatcttta tgacctacag
    20581 taattctgtt aatgaggttg cgacacttgc tcatgaacta ggacatgctt tccatagcag
    20641 cacgatgtgg gatttacctt ctttaaatcg cgaatatgcc atgaatgtcg cagaaacagc
    20701 aagtacattc gcagaactga tcgtagccga tgctacatta aaagtcgcaa aaacaaaaga
    20761 agaaaaaatc aatttgctag atacaaaact gcaaaatgct ttagctatgt tcatgaatat
    20821 ccattcccga ttcatttttg aaaatcgatt ctatgaagca cggcaagaag gattagtctc
    20881 agaagataag atcacagaga tgatggttga ggcgcaaaaa gaaggctatc aaggagcttt
    20941 agctacttac catccatatt tctgggctgc aaaattgcat ttctttattg atgacgtacc
    21001 gttttataac ttcccataca catttggcta cctctttagt ttgggcatct atgcttacgc
    21061 caaccaaaag ggagcaaatt ttgaagaaga atatatccat ttactacgcg atactgcctc
    21121 aatgacgacg gaagatcttg cgaagaaaca tttgaatgtc gatcttaccc aaccagattt
    21181 ttggcaagca ggtatcgaca tggtgactga agatatccaa acgttcatgg aattgacaga
    21241 agaatttatc tgatttctat tttatcacaa taaaaaaaga gttagtccag aatgggctaa
    21301 ctctttttga ttaatcattc ttacatgctg acagcaaagt caggggcaaa ccattgaact
    21361 gaaccaactt ttacgctttc gcctggttga ggagcatgga tatattgtcc tccgcctaaa
    21421 gcaatcgcta cgtggtaagt tccgccttgt gacccccaga ataacaagtc tccagctttt
    21481 gcttgagaaa ctgaaatttt tgttccagct gattcttgag gaactgtcca accaccgatg
    21541 tcacgaccag ttacttgcat gtaaacatag cgtgtgaacc ctgagcagtc aaagccactt
    21601 ggatctttac cgccccaaac atatggagta ccaatatatt tgtaagcttc tgctacgatt
    21661 gctgcaccat tcacacttcc agaaggagct ggagcaggtg ttacaggttt tggttgttca
    21721 ggtgttggtg ttggcgttgg agccggagta ctacttcctg tgccgtttcc tgtatcaaca
    21781 ctttgatctg ttgatggtgt tgtaggcgca ggtgttgttg attcttctgt tgttgaagat
    21841 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcactgttgt tgattcttct
    21901 gttgctgaag attcaggcgc tgttgttgat tcttctgttg ctgaagattc aggcgctgtt
    21961 gattcttctg ttgaagattc aggtgttgtt gattcttctg ttgctgaaga ttgtgtagct
    22021 gatgatgatt cttcagtcat tgaagattgt gtagctgatg attcttctgt tgctgagctt
    22081 tgtgcagtag atgaagcttg agtagcttgt gcttcagcct ctgcttgttc gcgtgcttct
    22141 ttttcagctt tttcttgtgc agcttgttga cgagcttgtt ctgctagacg ttgttgttca
    22201 cgaatacgag cttgctctgc ttcagcttct gctttttgac ggttcaagtc agctttcttg
    22261 tcttcagcag ttgcttgttc agcagctaat gaagttttca gtacgttcaa atcagcttgt
    22321 ttagataaaa gatcgccttt ttgagattcc aaagcagctt ggttttcagc taattctttt
    22381 agtttagcat cgttttcagc ttttttgtct tctacagctt ttttatcttg tttttgttgt
    22441 tccatcaagt cgttgtttgc ttttaccatc gttgtcattg cttgaacgcg tccaatagca
    22501 tctgctaatg aatcagcatt caatacagca tcgatgtagt ttgagcttgt gttgcttact
    22561 tgtgcttcgc gtgcttgttt ttggattgta tcttcacgtt tttcaatacg ttcttgtaaa
    22621 tctgcaatgt cttttactaa ttgtgcagat tcttgacgca atgtatcttg ttttgctaat
    22681 aggtcttgtg cttgtgtgtt gatttcagaa acttggcttt ctaaggcatc gatttgtgat
    22741 tgtgcatctg cttgttgatt tttcaagtct gcaatctttt gatcttgctg ttgtatctga
    22801 gaatcaaaat cgtccgccgc ggcagcgatc ggtgatgcta cggcagtcaa ggtcattgaa
    22861 cataccatta ctgctgatat taaactcttt ttcactcttc attcctccga ctggcttaat
    22921 ttaataaata tctaaatata tttaagtctt tcttaacgat ataaaaattg taccatagca
    22981 gtgtgtcaac gatataatag ttatgttaca aaaatgtttc aaaacaactt ttaaaaatga
    23041 caaaactgtt cgtttcagaa aatgatcatg aaaaagccgc gttaagtcta gcatttctta
    23101 agataacaac gattcttttt cgctttcgac ctaaaaataa aaaaagaaat tattcatcac
    23161 tgaataattt cttaaaggga aaaatgaata atacaaatat aatcatgttc aacagcagtg
    23221 taggtcctaa aaaccttgta ataaaatacg tgttatttac tactgctaat ttaaaaatca
    23281 actggaccac catcgtaaac aattcataac ccgtgacaaa gatgatcata ctgaaaaatt
    23341 cagtaaagat gttgacatgg ataacgtctt tcattacata catcaaccat acaattaaag
    23401 ggagagctac tgcatagata ccgataacgc caatatagta agcgtcatag atagccccga
    23461 gaacaatcgt ggtaatcagt aaataacgtt tttcaaacgc catactgcaa cataataatg
    23521 ccaatatcag aaagtgggca tttgacatat aggtgccttt cgaccactcc cctagcattc
    23581 ttgttaaatg accatctatc aacatcaaaa agaacaaaac gattggcaga tagtacttca
    23641 ttgtttcttt cttcaacatg gactaatcct ccgctagccg ttggacaatc gtcacaactg
    23701 acacgtcata catttctgca taaggtttca cataaacttc ccgatccagc ccataactat
    23761 ctggtttcgt tttaataacc gtaccgatcg gcaagttagc tggagaattc cctccaagac
    23821 cggatgtctg gacaacatcc ccttctttga tatccgtatc accagttaat tgggtcacca
    23881 ctaaggcatg gagcttttca tcatagtttt taagcaaacc aaacgcttcg ccattagccg
    23941 aagatacccg tactggaaaa tgattggagc tttcattaga ggatgacagt aattcgattt
    24001 tagacgaagc cgtattgacc tcgatcactc ggccaatcaa tcctttttgc gacatgactg
    24061 ccatatttgc ttcgataccg tctttagaac ccttgtctac gatcagcatg tcctgccaac
    24121 tgtcaggcga acgagtaatg acatttgccg ttactttttc gtaactagtc agcgtctgat
    24181 tcaactcaag ttcttttttc aacgcttcga tttctctctc gtaattcttg ttttgctgtg
    24241 aaacgtcatc atagctatcg attttttctt ttagccgctc attttcggca taagttgaaa
    24301 aaagattatg gacagaatct actccatttc gtacccaccg tactggggca gagattgttt
    24361 tatcaaccat tgcaacactg tcattaacga tggattggaa gaaattgggc tttccttcat
    24421 tcgctcgctg cgcagcggtc acacttagta tcgtcaccac gatgataaca ataaccaagg
    24481 taataataat atttttatta ggattgaact tcttcacaaa gacacctcga attaattaga
    24541 ctcttgtgtt caattttatc actaaatgcc gtgaaacaaa aggtaagttg ctcctcttaa
    24601 gctttttttt agcaaataat agattctgtc atttttagcc tgaaagacaa atttttttat
    24661 ttgtttatgg atcaatcttt gctttgaata actgcaatca taccatctga aaaagaaaat
    24721 tctgcggtat ctgaaagaaa ttcgttactt gcataagatg tcggatattc tacttcttta
    24781 ttttccaata catacttgct gccttttaat gtaagattcg agacgggagt caagcagcaa
    24841 taagctaaat acttcatatc tggtatctgt cttactatat gctctccagg caaataataa
    24901 gacaaataat tttgacaatc tctgataata agctgatggg caaagggttt gaagcgaggt
    24961 tccataccta accagagatt ggctaaaaga tgatccaatc ttccgcccgt agctccaatc
    25021 aaagtgactt ccgcttgcgg gtaacgttca aatgttttta agatacctaa ctgtgtatct
    25081 gtatcgtctt tttctgcagg ggaacgggta tactctttgg cttttgcaaa tacttccttc
    25141 tgctcttcgt tcgacaatga atcaaaatcg cccactgcca gatctactgg gtagcctgct
    25201 tgaagcaggt acagcgcacc acggtctatc ccgacatagg catcgtattt ggacagcaga
    25261 gactgcggcc agttttgcgg attacctcca gcagctaata aaattttcat ttagtctaat
    25321 gcctctttta atcgttcgat ttgtccgact ggattttcgg ctccatagat atatgatcct
    25381 gcaacgaaga catccgcccc tgcatcttta cagatttttg ctgtttctgg aacgattccg
    25441 ccatctactt cgattgcata agtccaattg ttctctctac gtagatcagc gagttccgta
    25501 attttttcta ctgtttcttc aataaagctt tgtccgccga acccaggatt gacagtcatg
    25561 actagtactt gatcagccaa aggcaaaaca tgtttgatca tggagactgg tgttcctgga
    25621 ttgataacta ctccagcttt aactcctaag ctttttgtca tttgaagtgc ccgatgaata
    25681 tgaggagttg cttcgacgtg gacagtaatg atatctgctc cagcttttgc aaatgctgga
    25741 atgtagtttt ctggatcaac gatcatcaga tggacgtcta acggtaattt agtaacagga
    25801 cggattgcct gaacaatatt tggccctaat gtgatatttg ggacaaattg gccatccatt
    25861 acatctacgt ggatgtaatc tgcgcctcct ttttccacta actcaatgtc tctttgtaaa
    25921 ttggcaaaat ctgcactcaa aatggatggt gctatcttca ttcttgtttc ctcctatttt
    25981 cgtttacctt ctttttttgc atacattggt tttctttttt cgatttcttg taagaattgc
    26041 aaataattgt cgtaacgtgt ctgtgcgata ccacctgttt ctactctatg ttttacttcg
    26101 cagccaggtt ctttagcatg catgcactct ctaaatttgc aatggacaga agcttctaca
    26161 aattcaggaa attgtctcgg cagttctcct gcttcaattg tcaaaaagtc aatcgagcta
    26221 aatcctggtg tatctgctac taacccgcca tagataggaa tcagttccac atgacgtgtt
    26281 gtatgccgtc ctcttccaag tgcatcagaa atctctcctg ttgctaaatt cagttccggt
    26341 gatatttgat tcagtagcgt cgattttcct gctccagact gacccataaa gaccgatagc
    26401 cgttctggga agtaacggat cagttctgtc gtatcacccg tatgattggg tacaatcacc
    26461 ggatagccta ttttagtata ggtttgcttg atctcttcga ttttttctgg gtcgtctgac
    26521 aagtcggtct ttgtcaaaaa aataatcggt tcgatcgact cgtattccaa ggtaactaga
    26581 aagcggtcaa gtagattata agaaaatgca ggctctacga tacttgtgac aatgattcca
    26641 agatcaacat ttgtgactgg tgggcgaact aattgatttt ttctcggcaa gatttccaga
    26701 agatagccgt ctgtttgatt ttcactctca aagatcacct gatctccgac aagcggcgtg
    26761 attttccgat tccggaaatt tcctcttcct cttgtttgat aggtctctcc gtttgcgtat
    26821 acatagtaaa aaccgctgat tgcttttctg atttgtcctt tgataagtgc cacctccgtt
    26881 tttgtttatt ttaccatacg aagaggaaag taggtgttat tccatgcaaa cttctcaaag
    26941 tatatggctt gaaaattgat caaaagagat agaaacacaa aaaagagaat gcaacaaatc
    27001 aatgtcgcat tcccttctga tatattttat tcagcactta ttttgaactt tctgaggtgc
    27061 tagctgatga acttgtggag ctggaagatt cttcttttga agagttgctt gtgctactgg
    27121 agctacttga gctgctagaa ctgtctgaag agtctttttc agaactagaa gacgctggat
    27181 ctggtccttt agagtaaatt acgttcacaa ccattccttt ggtaattgtc gttcctgccc
    27241 ctggtactgt acgaatcact ttatctttat ccaccgtgtt tgaatattcg gaagtctcat
    27301 gcccgatata ttctgcaccg acactagcta aataactttg tgcttcgctt tttgtatagc
    27361 cggagatatc attcaattta ggctctgttc cttggcttac gacaaaattg atgtaagttt
    27421 cttctgctac aacttcaccc gaggctggat cctgactgat gatcgaacct gatggtacag
    27481 tgtcgctata gtcataagta gcactaatat tattgatatt gaatccttgt gtaacaagcc
    27541 aattacgaac agtttcgtag ttttctccta catgactact caaagtcact gtttctggtc
    27601 ctttgctgac tgtgaaagta atcgtgtctg ttttaggatc gacttctgta tcttctgatg
    27661 gagattgcga aatgatcatt ccgctttcta cctctgaact gaattcctct tctttttgaa
    27721 tcaagtcagc agaaaaccct aattctttca aacttgcttc ggcatcttca taacttttac
    27781 cactgtaatc atctaatttg atttttttcg tgccgctact aatatacaga gtgacttcgc
    27841 gtttttgctt gactgtcgtt cccgctgccg ggtctgtctt cactacatta ccttcttcga
    27901 ttttgtcatc tgcaatttct tctgtttttg ttgctacttc taatttcgct tttgcgagtg
    27961 tttctctagc agaagcttca gaaagatcag aaacatcagg aacaacaact tctcctcgcc
    28021 cgccagaagc aaagaataca gctgttccga ttcctaaaac agcaagaata gctaatagga
    28081 tcagccacca ttttttctgt cctttctttt taggatcagg cagaacttct tcctcctctg
    28141 gcaaggtttc gttttctggc ttgtcttttg gcagaggcat agatttgaat gaatcaggca
    28201 ttggtgcatc ttccgtaagg ggtgtgataa cttttgtttc attatccatc acatgaggct
    28261 gccatttttc ttcgtttgca cgagctggtg ataatactgt agaaagatca tcagacattt
    28321 cctcggctga cttataacgg tctgcaggtt ctttagccgt tgcccgtaaa atcacgtttt
    28381 ccagtgcttg tggcacattt ggatcaagtg cttttataga tggaagatca tcttgaaaat
    28441 gttttaaagc aattgttaca gcagattcac catcaaacgg tacgctaccc gtcaacatct
    28501 cataaaggat gatccctaaa gcataaatat ctgactgctt cgttgccata cttcctctgg
    28561 cctgctcagg ggacagataa tgaacagatc ccagcatcgt attcgtctgc gtgatcgatg
    28621 tttcagataa agcgatagca atcccgaaat ccgtgatttt tacaacacct tcattatcga
    28681 tcagtacgtt ttggggtttc aaatctcggt ggatgatttg atggttatga gctaaagaaa
    28741 tagcagaaag gatctgctgc ataatattta ctgctgtttc ataaggaaca ggataatgtg
    28801 tttggatata tcgtttcaag tccattcctt tgacgtattc catcaccaga tactgcatgt
    28861 tgtcttcttc accaacatcg taaacactaa caatgtttgg atgaacgagt tctgttgctg
    28921 ctaaagcttc tctctgaaat cgtcgaatcg cagtctggtc attttgaaag tcaaatcgta
    28981 agactttaac tgctacatca cgatccaaga ttaaatcgtg cgccaaaaat acatttgcca
    29041 taccaccgct accgatattt ccagtgattt gataacggcc atttaatttt ttgcccaact
    29101 cgatcataca ctgtcctcct tatattcgat aagaagaacg gtgatattat ccgctccgcc
    29161 tgcttcattg gcacgatcaa tcagctcagt tactttatga gacaatgggc cttcttgatt
    29221 gatgatcgtt cctatttctt cttcagacag catgttcgtc aagccatctg aacataacag
    29281 cagtcgatct tttagttgcc aaagatgagt agaaacatct acttcgactg ttccaggcat
    29341 gccgacagaa cgtgttaaaa tatttttcct tggatggttc actgccattt cttcgctgat
    29401 ttctcctgat ttgactagtt cattgactaa agaatgatcc tccgtcaatt gcatgatttt
    29461 atcttcacga atcaaataag ctctgctatc cccaacattg gcaatcgtga accagtcatc
    29521 tgacagagcg gccgctacga ttgttgttcc cataccgtta tattccggct gttcttgtcc
    29581 acgctgataa atcagcatat tttcttcttg aatcgattga atgaaccatt gggcgatttt
    29641 ttcatcgtca acagcttctt gtttttccca agcttcgcct agattcgtta ccgccatctg
    29701 actggcaatg tctccggcac gatgaccacc catcccgtct gctaatacag caagcttgag
    29761 acctgaacgg ctggtaaata cactggcata gtcttgattt gtgttacgtc gtcttcctac
    29821 atctgattga tattcaatct gcattttttc acctcattac tttttgcgca aacaacaaat
    29881 gaaaaatcca tctgtgtaaa actgatgcgg atacaaagtc aacattttct cttcgattga
    29941 tgattgtagc ataggattgg tcaaaacatc aatcctctca aaatcagggt gtctttccaa
    30001 gaaagcagaa acaacgtctt ggttttcttc ttttaagatc gtacaagtgc tataagtcag
    30061 aataccggaa gactttaaag ttggtgcgca gctttctaaa atttccaatt ggatttttgg
    30121 taaattcgct aattcatccg gctgtttttt ataacgaata tctggttttc gccgaagcag
    30181 cccaagacct gaacaaggcg cgtctactaa aatccgatca aactgctctg cttcgaactg
    30241 tttactgact tctctagcat ccatcttttg agcgtagaca gcagaagaga cacctagacg
    30301 tgctgcatta tcttcaatga gtttgacttt gtgttcgtgt acatctaaag cgaccacttc
    30361 tccaccgcat gacggatcta aaaaagaagc aatatgcgtc gtcttacctc cgggtgctgc
    30421 acaggcatct aagacatgat gttcaggctc gatttgcata gacggcgcta caagcatcga
    30481 actttcatct tggatcgtca tgacgccatc gtggaacaat gagctagaag ctaaatgccc
    30541 ttttttcgct actataccgt atggactgac ttggcttttt tcagctgtga tctcttcttc
    30601 ttgcaaaaca gtgatggcct gatctctgga aagtcggcgt gtatctactc gggcactagc
    30661 atggctaggc tgatatagcg ataaaccgag cttttcagtt tcttcgtatc cgatttgatc
    30721 caccagtcgt ttcgtcatcc atagaggcag gctgattttg acagaaagtc tttcgatagg
    30781 atcagcaatg ccttgcagat ctggtgctcc ttgacgctga taattcctca agacaccatt
    30841 tacaaatttc cctgtcccag gatttccttt tacttttgcg atttcgaccg cctcgtttaa
    30901 aatagcatgt gcagggactt tatctaaaaa ttctaattgg tatacagaaa gataaagaag
    30961 cgtcttgacc cagtcatcca ctttttttgc tttagcgatc aatggtgcaa cgtaaaattc
    31021 caatagtcgc tgatggctaa tcgtaccata gatcaattct gtaaataaac ccacatcttt
    31081 ttgatttagc tcgctttgtt tgatcatctc attcaacaaa agattcgagt aggcgccacc
    31141 cttgttcact cgctctaatg tcagtaatgc catatatcgt actgattttt tcattttttt
    31201 agggattttt ttcattattt cacctgctga ccaatctgaa cttgctgacc gcttccgtta
    31261 aggaaatcat gtacggcctg ttttccttta ccagctggct gtaattcatt gatggctaag
    31321 acggtctgtt taccgcaagc aatccataga ttttttttgt ctttccggat gatcgtacca
    31381 ggtgctttgt ctgtagtttc tgccaatact tcaaccgata ataatttcca gcgtatgccc
    31441 tcataggtcg tgaatgcaat tggccaagga cgcattccgc gtacttggtt gtcaatttct
    31501 tctgcagttt tatgccaatc gattgcttct tgttcccgtg tgatgtttgg cgaaaaagtt
    31561 gcttctgact cgtcttgagg tactggtttt tgtccatcca aaatattggg caatgtttct
    31621 agcaatagct ttcttcctaa aaggctaagc ttttcaaaca tcgtccctac atcatcttgt
    31681 ttagtgattg gtatgctttc ttgcgcatag attccgcctg catccatttt tttgatcatt
    31741 tccatgatcg ttacaccagt ttctttctcc ccattcatga tggcataatg aacaggcgca
    31801 cctccccgat atttaggaag taaagaagca tggacattga ttgcccctaa ttttggtact
    31861 tgcaataact tttcaggcaa gaattggcca aatgccgcag tgacgatcac atcaggcacc
    31921 aattcaatga tttcttccat ttctggcgaa ccggagattt tctctggctg cagcacacgg
    31981 ataccgtgct tcagagccgc ttcttttacc ggtgtcggcg taattactcg tttccgccca
    32041 actggacggt cgggctgtgt taccactgcc tggatctcgt aacctgattc tatcagccct
    32101 tcaagaatcg gcacagaaaa agcaggtgtg cccataaata ctagcttagt catcaagatg
    32161 ttcctccata tattcttcaa gttcttcttc cgggatctgc tgtatcattt tctcaatgaa
    32221 caagataccg tctaagtgat cgatttcatg ctggaaggca cgggctaaat agccaaaagc
    32281 cgtcacttct atctcttctc cgtctcgatc ataataacgc acggtcactt catctgctcg
    32341 cttgaccgtt ccatagacat gcggaatact gagacaacct tctacgtcaa ggctttcacc
    32401 ttttgcttcg atgatttctg ggttaatcag ttcaaatttc tcgccttcat ctacttcgat
    32461 cacagcaatt ctcttgtttt gtcctacttg aggagcagcg atccctattc cgtcattcgc
    32521 aatcattgtc tcatataaat tgtctaataa agcgattgtc tcgtccgtga ttacatcgat
    32581 tggctgagca gttcttttta atttatcatt agggtggatc aatataggat agcgcataat
    32641 ttggcccttt cttaaataaa gtttaatggt tcgttgtcaa ttgccacaaa aagaccttgt
    32701 cgctgttctt tctggcttcc attcaaaatt tcatccaaaa catgaggaag attcggttca
    32761 tgtttatatt tgatgattag ttgataataa tatcggtttt tcactctcaa aatcatgctg
    32821 ggcgttggcc ctaatagcaa gctttgaggg cttaacactt cttttagctg attggcaatc
    32881 tgaaagattt tctttgccgc tacttgttct tcaggatggc tggcggttat tttcacagta
    32941 aagtaataag gaggatagcc tccacgatgc cgtacatgca tttcctgctg ataaaactgc
    33001 tcataatttt gttttttagc taattctatg gcgtaatgtt gaggattgaa tgtttggatc
    33061 acgacttcgc ctgctttttc cgctcgccct gctcgtcctg aaacttgggt aagcaattgg
    33121 aatgtatgct cactagaacg aaaatccggt aaattcaggg aggtatcagc attcaacacc
    33181 ccaactaatg tcacttctgg aaagtccaaa cctttagcaa tcatttgtgt ccctaataat
    33241 atatctgctt cttttgcacc gaatttttgt aaaatctgtt cgtgtgcccc ttttcttcga
    33301 gtggtatcta catccatacg caaaatccta gcttgcggat aaagttctcg gagttcctct
    33361 tctacttttt gagtacctgt tccatagtag cggattttat tgccgccaca attaggacag
    33421 cgattgggaa taggttcttc atgtccgcaa taatggcagc gcattgaacg tgtatccata
    33481 tgcagtgtaa gagagatatc gcaattagga catggaagaa caaatccaca gtccctacac
    33541 atcacaaaag acgaatatcc tcgacgattg agcagtagga cagtttgttc ttttttgtct
    33601 aatcgatttt gtattttttc ctgcaaatta gcagaaaaag tagaggtccg atgattctga
    33661 aactcttcac gcatatctac gatctcaata gctggaagct gtgcagctgc tttggctcgg
    33721 tggtttaact gcaataactg ataaacgcct ttttgagctc gtgctcttga ttctaaagag
    33781 ggcgtcgcgc ttcctagaac tattgggcaa tgatgatatt tactgcgcca aattgctaga
    33841 tctctcgcat gataacgcgg tgtctcatct tgtttgtaac ttgattcatg ttcttcatcg
    33901 ataatgatca gcccgatatt tttcagcggg gcaaaaatag cagatcgtgc gcctactact
    33961 acttgcgctt cttcccgctc aatcttgcgc cattcatcat atttttcacc ttgggaaagt
    34021 ccgctatgta agaccgcaac tgattctccg aagcgtcctt tgaatcgctc gaccatttgc
    34081 ggagtcaatg cgatttcagg cactaacata atagccgttt tattttctga caaaacatca
    34141 gcgattgcct gaagatatac ttctgttttc ccgctgccag tgattccctc cagcaaaaag
    34201 acctgatctt tttgctgctg acctgctgtg atgatttgtt cgacagcatt tttttgttct
    34261 gcattcagtt ccaatgccgt cgtttggtca aatactcggt ctttataagg gtcgcgataa
    34321 cgttctgatt ctataaactc cagccagccc ttttcttttc cttgattcaa gacagcagta
    34381 ctgattcctt tatttttgaa ataagcaatt ggttcttctt ggctcagttc agataaacac
    34441 aaaagaagtt ctttttgttt cttggcattt tgccgtaatt ttgcccattc ttcttcgatt
    34501 tgcttttcag ttaacaaaga acggaccaaa cgaatcgttt ttactttatt tcgtgtatgg
    34561 acttcatatt tgatatctac taattgctct tggcgccagc gaatcaattg agaaaggctg
    34621 ccttcttctt ctgcttcctt ccaggaaatc acttctcgct gatcaaacaa tacctgaact
    34681 tctggtgtgt ctgccaaagg atagatcaat ttatcatatt ctgctttcat cacactcgga
    34741 agcatcgttt gtagacaagt gattttgaat gcgtaagtaa tttttttcat ataatcagct
    34801 aatgaaagta attcttcatt gaccaccgga gcaaggtcta gcaaacgaat aactgccttc
    34861 aaagatggat tagctgattc ttctgatttt tggatagcca taacaaatcc ttggacatga
    34921 cgattgccat taccaaaagg gacttctact cgcatcccga cttgcaaagc tgtttccatt
    34981 tcagagggaa ccaaataagt gaatggctga tcggtctgca tagtaggtac gtccacaatg
    35041 acttcagctg ttaatgtcat ggttcgtttc ctcctttttt tgtcttttct tatcaagcga
    35101 caaaaagttc cttgcctatt ttactagaga tcgatggatt tgtcttatct tctgccaaat
    35161 cctaacaaaa aattaacagc agataagaaa aaaaagaact gtgtcaaaaa gttcagacac
    35221 agccttttct accagacaat aagtggcgaa tgtttgaaaa ggaaacagct gggtttgctt
    35281 ttctttttag atgttcgctc tatttttctt tattacattt tttgctcttc acggatacgt
    35341 gattccaatt cgtgttgttc acgctctttt tgtgcttgac gttcctcttc ttccatcttc
    35401 aaacgttcac gttttaattc aggatgtgga tcattgacta catttcctgc atcgatttct
    35461 tctaaagctt gaccgacgct ttttactgaa tcaaaagaat ctagagtagg ctgtgcactt
    35521 gcatccaatt catgcgcgcg tttacttgct aaaatcacta gagaatattt tgaatttaca
    35581 cgatctaata gtgagtcaat tgaaggtttt aacatcataa gactacatct cctttaacat
    35641 tttaatatat ttaccgatta cgcgatctac tcgaaaatgt tcactggcaa taatgttttt
    35701 gattcgttca actgctagcg gcacttcatc atttacaaca gcatagtcgt aaagagccat
    35761 catttcgatt tcttcttttg caactttcat tcgttcttcg attacttcat ctgcatctgt
    35821 tcctcggcct acgatccgtg attttaattc cgctaaatct ggcggagtca aaaagatgaa
    35881 tacaccatcg ggcacttttt ctttgacttg ttttgctcct tggacttcaa tctccaagaa
    35941 aacatctttt ccttcatcca atgtcttgtt gatatatgac aaaggagttc cataataatt
    36001 cccgacatat tctgcgtatt ccagcatctc tccagcttcg atcattgatt caaactcttc
    36061 tttgcttcgg aagaaataat caacgccttc gacctcccct tcacgcattt tacgggtagt
    36121 cattgagatc gaatactgaa aatcattatc ctcactctca aaaattgctt ttcgtactgt
    36181 gccttttcct acaccggatg gaccagacaa cacgattaat aatccacgct ctgacatgac
    36241 gacgtccttt caactagtct ttttgtactt atcgtttatt ttgcactttt tttctgcaac
    36301 tttcaaggtt atctttaatt atagctagaa attggtaaaa aagctaccct gtaccaagag
    36361 gtcgtaaaaa agctgtcctg catcaagtaa taagaacagc caaacataaa cagcttctca
    36421 tgtttttcgt ttggttgggg ttattatcgc agatgcaagc ttttgaacgc cgtgtataag
    36481 aggtcgtgaa gaagccgatt agtttcgagt atgaagaaaa attttgtgaa aatagtttct
    36541 cacatttttg cataaatttg gcttaatac
//
LOCUS       DAFLWQ010000022        36530 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.023, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000022 DAFLWQ010000000
VERSION     DAFLWQ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36530
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.023"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            331..651
                     /locus_tag="L1V16_001078"
     CDS             331..651
                     /locus_tag="L1V16_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBN1275433.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            805..1710
                     /locus_tag="L1V16_001079"
     CDS             805..1710
                     /locus_tag="L1V16_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1275434.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            1707..2480
                     /locus_tag="L1V16_001080"
     CDS             1707..2480
                     /locus_tag="L1V16_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBN1275435.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(2661..4085)
                     /locus_tag="L1V16_001081"
     CDS             complement(2661..4085)
                     /locus_tag="L1V16_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1275436.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            4296..4742
                     /gene="nrdI"
                     /locus_tag="L1V16_001082"
     CDS             4296..4742
                     /gene="nrdI"
                     /locus_tag="L1V16_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBN1275437.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(4807..6789)
                     /locus_tag="L1V16_001083"
     CDS             complement(4807..6789)
                     /locus_tag="L1V16_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1275438.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(6803..7699)
                     /gene="murQ"
                     /locus_tag="L1V16_001084"
     CDS             complement(6803..7699)
                     /gene="murQ"
                     /locus_tag="L1V16_001084"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBN1275439.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(7702..8763)
                     /locus_tag="L1V16_001085"
     CDS             complement(7702..8763)
                     /locus_tag="L1V16_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBN1275440.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(8974..9540)
                     /locus_tag="L1V16_001086"
     CDS             complement(8974..9540)
                     /locus_tag="L1V16_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBN1275441.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(9568..11070)
                     /gene="eat(A)"
                     /locus_tag="L1V16_001087"
     CDS             complement(9568..11070)
                     /gene="eat(A)"
                     /locus_tag="L1V16_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBN1275442.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(11328..12449)
                     /locus_tag="L1V16_001088"
     CDS             complement(11328..12449)
                     /locus_tag="L1V16_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBN1275443.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            12575..13516
                     /locus_tag="L1V16_001089"
     CDS             12575..13516
                     /locus_tag="L1V16_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBN1275444.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(13666..14562)
                     /locus_tag="L1V16_001090"
     CDS             complement(13666..14562)
                     /locus_tag="L1V16_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBN1275445.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            14831..16171
                     /locus_tag="L1V16_001091"
     CDS             14831..16171
                     /locus_tag="L1V16_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1275446.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            16389..16832
                     /locus_tag="L1V16_001092"
     CDS             16389..16832
                     /locus_tag="L1V16_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBN1275447.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(17336..18754)
                     /gene="nhaC"
                     /locus_tag="L1V16_001093"
     CDS             complement(17336..18754)
                     /gene="nhaC"
                     /locus_tag="L1V16_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBN1275448.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(19157..20380)
                     /locus_tag="L1V16_001094"
     CDS             complement(19157..20380)
                     /locus_tag="L1V16_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBN1275449.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(20411..21250)
                     /locus_tag="L1V16_001095"
     CDS             complement(20411..21250)
                     /locus_tag="L1V16_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBN1275450.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(21267..21947)
                     /locus_tag="L1V16_001096"
     CDS             complement(21267..21947)
                     /locus_tag="L1V16_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1275451.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(21949..23022)
                     /locus_tag="L1V16_001097"
     CDS             complement(21949..23022)
                     /locus_tag="L1V16_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1275452.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(23078..23316)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(23359..23592)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(23669..24340)
                     /locus_tag="L1V16_001098"
     CDS             complement(23669..24340)
                     /locus_tag="L1V16_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBN1275453.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(24427..27105)
                     /gene="mgtA"
                     /locus_tag="L1V16_001099"
     CDS             complement(24427..27105)
                     /gene="mgtA"
                     /locus_tag="L1V16_001099"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBN1275454.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            27764..28201
                     /gene="ndk"
                     /locus_tag="L1V16_001100"
     CDS             27764..28201
                     /gene="ndk"
                     /locus_tag="L1V16_001100"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBN1275455.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(28223..29089)
                     /locus_tag="L1V16_001101"
     CDS             complement(28223..29089)
                     /locus_tag="L1V16_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBN1275456.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(29249..31342)
                     /locus_tag="L1V16_001102"
     CDS             complement(29249..31342)
                     /locus_tag="L1V16_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBN1275457.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(32091..32714)
                     /locus_tag="L1V16_001103"
     CDS             complement(32091..32714)
                     /locus_tag="L1V16_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275458.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(32873..34270)
                     /locus_tag="L1V16_001104"
     CDS             complement(32873..34270)
                     /locus_tag="L1V16_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1275459.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(34302..35273)
                     /locus_tag="L1V16_001105"
     CDS             complement(34302..35273)
                     /locus_tag="L1V16_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1275460.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            35647..36072
                     /locus_tag="L1V16_001106"
     CDS             35647..36072
                     /locus_tag="L1V16_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275461.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
BASE COUNT        10573 a         7608 c         6399 g        11950 t
ORIGIN      
        1 aggtaaagct ttttttaatt tattgcccga taatatatag aaataaggtc tagttactgt
       61 tttttttaaa tgattaataa ataacaactt ctttctatga aattgcaaag cattcatctt
      121 cttttccgct aacgatatat ccgtcagtgc ttggtacact ttactaaaaa gtatgagatt
      181 gccgatatct ggataggtgt gctatactac agaaaaagat atacaatctg ccaccgggta
      241 ggataaagag gatgatcatt ccattaggtc tttgaaggga tgattttcct ctttttgtgt
      301 atttttttat agttaaggag gaatgtaagt atggcatgga tggaattaat catagcagga
      361 attttggaag tattctggtc aacgatgatg aaatggagtg atggtttttc taaaatcaat
      421 tattcttttt acacagtgat tggcatgatt gctagttttt actttttgtc aaaggcaatc
      481 aaaagtttgc cgatgagtct ctcttatcct atctggacag ggattggcgc agttggttcg
      541 gtcataattg gtgtggtctt gtttcatgat aagctgaatc tttccacttg gttctttgtg
      601 gggatgctac tcatcagtat cattggcatc aagattacta gcggccacta gacacttgga
      661 ataagtactg atcagaaaaa ataagccttt ttatttaata ttcaattttt ttatgaaaaa
      721 ataagaaata agtccaatga cctagcgact tctccactca tcaggtgtat gcttgtacta
      781 tctatagaaa aggagtgaat atttttgaaa agtctttcgg tccaagaatt atccaagaac
      841 tttggtcaca aacaagccct cagcgatgtc agttttagct tatcccctgg caaaatcgtt
      901 ggattagtag gtcctaatgg cgctggaaaa acaacgatca tgaaagctat tttaggactg
      961 atccattact cagatggaac aatctgtatt ggtgaaaatg agatttctcc ctctagtcat
     1021 aaagggttgg aacaagtagg agcattgatc gaatacccgg gtatctatcc attcttaaca
     1081 ggctatgatc atctgaagtt attctctgaa accaacgatg tatctgctat cgacactatc
     1141 gtgaatcagc tcaagatgga aaagtacatt cacaaaaaag cgaaatccta ctcgttggga
     1201 atgaaacaaa aattgggaat tgctcttgcc ttactgaacc atccgtctat cgttatttta
     1261 gatgagccga tgaacggttt ggatccacaa gcaacaagag atgtgcgaaa aatcattacc
     1321 gacttggcta ctcagggcac ctctttcttg atctccagtc acttactcag cgagcttgaa
     1381 aaaatggtcg atgagctgat cctgatcaat caaggaaaga tcatcaaaca atgtacaatg
     1441 gctgaattga accaaacagc gcaagatttc atcgttatct ctacaacaaa tgatctagct
     1501 gctcgaacga tcttgacaga agctggatat actttggaag atcctgataa aatcaagctt
     1561 ttaaaagaaa acgaagaatt attaggaacc gtgatccagc tattgtctgc acaaaatatc
     1621 catgtgacag acgtccagca tctgacgaat gatttggaat cttctctatt ggaaattctg
     1681 gattcagtaa agggggaaga agaaaaatga cattgcttgt aaaacaagaa ttatttaaat
     1741 tgatcaagaa aaagtcaact gctgttttat ctgttctatt agttgttttg ctcataggaa
     1801 cagcacttct agccaaaaaa tacacgacga tcattgatcc agttgaaatg actgctcagc
     1861 tttttagtgc cacatcttgg attgtcttta tcatgattgc agctgcaagc acgatcattt
     1921 cgatggaagc acaatatggt acattgaaaa atctccttta tcgaaagtat tctcgaggag
     1981 aaatattagt aagcaaatgg atcacattag ttatttattc tgtttattta taccttttag
     2041 ctattattgt cactgtgttg atgaaactga ttcttttccc ttcgatttcc ttcacggaga
     2101 aggtttctac tggtcaaaca ctgatccaaa gcttgttcac ttatactttg ggtagttata
     2161 tcggtttatg gctgatttta agtttagtgt tgatgattgc ttgctttatc aatagttccg
     2221 gcgcatccat ctcagcagga atcgtctttt attttgcttc gtcaatcata tctggtatcc
     2281 ttattgcact catccaaaaa tgggagtgga tcaaatggaa tccgatcagt atgttgaatc
     2341 tgcaaaacca aattggaaac gaagagatca tgaagcaatt gactcatctt tctactaatc
     2401 aaatgctatt cggtaattta gcttacatcg ttttgttctt agcattagga tatctcgtat
     2461 ttaagcgaaa aaatgtatga tgactcatca aaaaagaggc tgtgaaagag acgttcagcc
     2521 ttattgccga ttggctgtct cttaaacacc gtttattctg aaaaaggagc tgtgacaaca
     2581 tttgtgtcac agctcctttc ctagtatgtt tttgaataaa cgacaggctc acaacctctc
     2641 tttatacttc ttttatactt ctatacgtga agcatcccag tggcaaataa aaccattgca
     2701 atcactccga ccatcgtcac acctataagt aaaatcttat ctaagtggat atgttgtaca
     2761 ggctcgtttt gctccttacg tgctttgagg taaaaataaa tgcctggcaa gaaaagaaca
     2821 agaacaagca ttacttcatt aaaggctacg actagcatag cccatacttg aaaggcactt
     2881 gctaaaagcc ctactaaaaa ttggacccat tctttccgct gataagaaag tttcatttgg
     2941 tacaatccta agaaaagcca cgtgaagaaa atagctgctg taccaagtgt gtaagcaaag
     3001 ttataagcac tgtcagtgaa taataatgaa agtaaaaaga cattcgtaca taacgtcgtc
     3061 aatacgatag cataagttgg tgccccattt ttgttgagtt ttccccatgc tttaggcaaa
     3121 agtccgtctt cagccatgtt tcccattgtt tcaatcggta agatcgtcca tgagagccaa
     3181 acaccaacta aagaaatgat caaaccgccg ttgatcacga ctgctcccca tttaccaacc
     3241 atcatttcaa acacatagcc catagcaggc tgcgccttga tcgtttgcag ctgattcatc
     3301 gtcattgtcc catatggaag catggaaacc aagacgtaaa taataatcaa gccgaatatc
     3361 cctagaatcg ttgctttccc aacatctgat tgtttttttg ctcgtgaacc tacgacagag
     3421 gctccttcaa taccaacaaa tacccaaagc atcaccatga tgcaactcaa tacttgactg
     3481 gaaaacggga tcggctgtcc attcgcattc aatataatgt cgctagaaaa gttatcaatg
     3541 aattgttgga tcgaaaacgt gctgatagct actacaataa ataaaaataa tggcactaat
     3601 ttacagaatg tgacgatagc attgacgaaa ctagcatttt cgactccccg attcactagc
     3661 catgcatatc cccataaaaa gactgtactc atcacgatcg atgccagatt ttgcccacct
     3721 tcaaatactg ggaagaaata tcctaatgcg ctcatcaaca atgttgcaaa agctacgttg
     3781 cctaaccagc atgtgagcca gtaaccccaa ccgctgataa aaccagcgaa acggccaaaa
     3841 ccttcttctg cgtaactaaa gatcccgcct tttaaatctg gacgtttttt attgatatta
     3901 ttgatcgaca aggagagcat caacattgct gttcctacga gtacccaact gaaaatagct
     3961 gggccgccag ccgatccgga gatgtccgtc ataataccaa atacgccacc tccaatcgct
     4021 gaaccaatta ctaaggcagc aagtggaatt aaaccaattc cttttttctg ttgctctgta
     4081 tccatgtaag catcctccaa aataaaaccg cttttatcaa aaagtataac aaaccttttt
     4141 tatttttact taattaataa aaactttaat agaaatataa ttctaccggc ttttttctca
     4201 ttatacaagc aaagcgccta gtccctttcc aaattacacc accaaaaaac ttaaaaaaga
     4261 tgctatacta aaaggaaaga attggaggat gatccatgaa cattttatat atatcgattt
     4321 caggaaatac gcgtgccttt gccaaacatc tagcagaata tgctgaaaaa atgcatgcag
     4381 aagatcctgt caatcctgaa gttactttaa aagaaatcca tgaaaatagt gattttacga
     4441 aagaaacaga accatttttt actttcgttc ctacttattt agacggcgga aatggtttag
     4501 ataacggtga tacagaaatc ttgaccgaaa cgatgcgtga atatctggaa catgaagaca
     4561 atcataaact ttgtcttggt gtagtcggta gcggaaataa aaacttcaat aatcagtatt
     4621 gtctaacagc caaacaatat gcacaaacat ttggctttcc tttcttggca gattatgaat
     4681 tacggggaac accatctgat gtgacacgaa tttatcagat tttagcagaa aacaataaat
     4741 aataaaaaag aagaagctga aaaatagatt tcagtttctt ctttcgtttc tattgtttct
     4801 atcatattaa gctttgacat ccatcacagg tgcttttgct tttgctttac ctgttttttc
     4861 caagacaaag ttttttacac gatccatatt ggttaccaag acgatcatgg atgtttcttt
     4921 gcctgctgct ttgatcgctt ctaagtcagc ttctgctaca agcgtatcag gtgtcacttg
     4981 ctgcccttct gttactttca catcaaatgg cgtaccgcct aagtcaactg tgttgattcc
     5041 catatgaagc aagatttcta aaccatttgg cgttgtgatc ccaatagcgt gtttcgttgg
     5101 gaagacagag ctgactaccc cagtaactgg agaatagata tgtccgtttt ctggttctac
     5161 aaagtagcct tcacccatca tcttttgtgc aaaaactgga tcacttgctt tatctaaaga
     5221 aacaactgtt ccgtcagcaa ctgatgagag gatagtcaca ctttcagctg aagtttgagg
     5281 tactactttt tcaggcactt catttactgt ggctgtttca gtcgctaatt cttctttttc
     5341 taaacggtct ttaggaatac cgaagaagaa tgtagcaacg aagccaccag cataagctgc
     5401 caataatcca aggatgtagc ctaaccattt accgtcagag atcaatggga tcaaagcggc
     5461 tcctgaaggt ccaatagcga tagccccgac atttccgatc attccgatca ctgccccgcc
     5521 gatacctcca ccgatacaag cagtaataaa tgggcgtcct agaggtaatg ttactccgta
     5581 aatcaatggt tcgccgattc ctaggatccc gactggtaaa gctcctttga tcatttctgt
     5641 taattcttta tcttttttgc agcgaatcca taatgccaat gctgcaccca cttgtcctgc
     5701 accagccatc gcaagaattg gaagcaatag cgtacgacca gtttcatcaa tcatttgcac
     5761 atggattgga gtcaaaattt gatgcagtcc gaacataacc atcggcaaga ataatgtgcc
     5821 tagaacgaag ccggcaaatg ctccaccaac gccaagtacc cagttgatcc caccgaccat
     5881 gccatcagaa atgaaacctg ctaaaggcat gatgaagaaa atttcaatca gaccgatggc
     5941 aatcaatgaa agagttggtg taacgatgat atctaccgca tcaggtacta ctttatgcag
     6001 ttttttctca acgattgaca atagccaaac agcgaagatg acacctagga tcccaccttg
     6061 tccagctgca agagcttcac cagtaaataa gtttttcagt ggtgcttccg gattcatccc
     6121 tgtcagcatc acaacggccc cgataactcc accaagagtt ggtgttgcac caaaaacttg
     6181 tgcagcattg atacctgtat agataactag gtagctaaac atcccgtttt tcaagatgtt
     6241 catcacatcg atatattgtt gccatgttgc tgcatcaagt gttccggctg tgactaagtt
     6301 tgctaaaact gcggcaatcc ctgccacgat cccagtaccg acaaatgcag gaatcattgg
     6361 cacaaagata ttagaaatgt cttttaatac cgatttgatt ttagatggtt tttgtttcga
     6421 tttttgtgcc gctttcattt cttgtgcccg ttcgtttaca cggtcttttc cagatgctga
     6481 tgaatttgct gtagctgtac ttacagaaga aagtttttct cctaatttca cgcctgccaa
     6541 atcaaccatt tgctgtgcta ctttgttcac tttcccaggt ccgatgatga cttgaagctg
     6601 ttcatcttct actacaccaa gcactcctgg aatcgctttt aattcagaga catttacaag
     6661 atcatcattg atgatcttca tacgcacacg agtcatgcag tggacaatgc tttctacatt
     6721 gcccatgccg cctgcccctt tataaatttg ttttgccagt tcttccaaag tcagttcgtt
     6781 ttttgccatg gtcttttccc cctcataagg tcccttttac aaatccgttt gcttcagcta
     6841 attttgcttg agcttcctct ttatcactat ttgtcaaaat catgacgata gccagcttaa
     6901 cattttgatc tgcttcttca aagtactttt cagctgtttc gtaatcagct tctgtcgctt
     6961 gcatgatgat tcgttttgag cgttcgatta gtttttcatt tgttggtttg acatcgacca
     7021 tcaagttatt gaatacttta cctataccaa tcatactgat agtagaaatc atattcaaga
     7081 taagtttttg tgctgttcct gacttcaatc gagtagagcc tgtcaaaaat tctggacctg
     7141 catcgacttc gattgggaaa tccgcgtgtt tactgatttc ggcttgttta ttgcaagaaa
     7201 tcgttcctgt gacagcaccg atcgattttg cgtaatctaa tccaccgatc acatatggtg
     7261 tacgaccgct agctgcgata ccaataacta tatcattttt tgtcaaattc agcttgatta
     7321 gatcttcttg ccctagctca taagaatctt cggccccttc gacagctaca gtcattgctt
     7381 cttctccacc agcaattaga cctatgacca tttccggttc tacaccgaat gtcggtacgc
     7441 attcagcagc atctaacaca cctagtcttc cacttgttcc ggctcccata taaatcagac
     7501 gtccaccttt tttaaaggac tcaatcgtgt tagcaatcac tggttcgata cttgtcagtt
     7561 ctttttcaac cgcagcggcc actttctgat cttctttgtt cattagttga acggcttgag
     7621 aaatactcat ctcatctaat ccaaaagttt cttggtttct gcgttccgtt gttaggttct
     7681 ctaaattgat tttgctcatt tttatcttcc ttcttttctt ataaattgat agttcatacc
     7741 agctttgatt tggttgatca atggtagctc ttctttgata actttagcta ctacattcac
     7801 tttttcatcc gctggcaaat catatttggt taattggatc tcacccatat agcgcaaata
     7861 cttttcgtta tctaaagtaa tagacccttt catacgcgta gctgtatttc ttgctgggat
     7921 aggcggaatc tctcgaaaac gtgcatctac gcttcgtatg acatctcttg catcgtcttg
     7981 ccgattcgta tgcttcccta atatatattc gtaaaattct tcatctacag gttccgtatg
     8041 gagcaagact gtctgttctt tttggaaaga agcaaattgc tcctgaacgt tttctgacag
     8101 acctgcatct ccgatgtaaa caatatccgt gttacttgct aatagatcta gagcgcctgc
     8161 aagaggatgg atccctcgat gttcttccaa agttggcaat ccttgatata gtgggcctct
     8221 caactctgta tctcctggta caaaaccttg gacaaggaga ccttgaattt tgagccattg
     8281 attttttttc tgataccatt ctttgtccag ccctgtttcg ggacgtggat aataattatg
     8341 ccaagcttca atctgtgaga aatcagcttc tgcttctttc aattcatcga tatctttagg
     8401 cgtgatcgtg ctagcattca aactgatttt caattgatgt gaccagtcgg caatctgctg
     8461 attggaaata tgataatcca ttcttaaacc tgttacacca attgctttca aaggcgttag
     8521 atcttctaat gaaaaacccg ctcgttccaa tgcctctcct gaaatatcga ccatcaattc
     8581 tagtttattc tttttcgctt cgcttcctag ttcgatcaat cgcttttgat atgccgaaac
     8641 atcatcttct ggtatatgca tggaagtgaa aataccgaca aagccattgg atgccatttg
     8701 gcggatatac tgtttcttct cttctgacaa agaatcgttc ataaatattg aaaagccaaa
     8761 catattatcc ctctttttct gtatccgtct tcatttctat gactagagta tatatctaaa
     8821 gaaacaaaat ttcaatactt ttattaaaat aattaaattt catttctaaa ggttgagttt
     8881 atattatcaa aagaattgtc ataacctaaa aaaggcactg ctaagcaaaa gcagtgcctt
     8941 gaaatatttt atttaaataa cacaaaaaca taattactca taagaaacca attctgtatt
     9001 atctaccatg aatgtaaaga acccctcatt aggcatcgga tgaaaataag cattgatcac
     9061 tcttatcaag gcattatggc aaactaacag atagacattt tcttcgtctt cgatgcattc
     9121 tttcaataaa ggaacgatcc gtgcatacac atctaagact gactccccat ttgggaatcg
     9181 tacagcgaac gctaaacgtg ctttttgaaa gttctcatct ttgcttggca gtccatcata
     9241 atccccaaaa tccatttcta ccaatcgttc atcaacggtc agcggcaagc tgagacgatc
     9301 agcaactgct tgtgctgtat ctcttgctcg ttgaagaggg gaatggatga ttttcgtgat
     9361 tggaacaggc aaatctacta ccttttctgc tagtttctgt gcctgcatct gtcctttttc
     9421 agtcagcggc acatctgccc gtccgcaaac taatccttgt gcgttccaag ttgtttctcc
     9481 gtgtctcgtt acataaagca tgtgattctc tccttcgttg gcaaagttcc ccttaaccat
     9541 accttgttgt tcttgagatt acaagggtta gattctctca agagaaataa tctcagtaga
     9601 tactttatcc aggaaggttt gatcatgttc cactagtaac atggcaggtt tcacgttcaa
     9661 gatcagttgt tctaattgtt cttgattgaa gacatccaaa taattcaatg gttcatccca
     9721 tgtatatagt tcagctggct gtgataaaga tttagccaat tccacttttt tccgttggcc
     9781 catactcatc tgctcgatct tgttatgaaa aacatctctt tccatcccaa gctttcggag
     9841 gttgttcaaa aatgcttggt agtctacttg gtttttctct gcaaattccg ccaacgttcc
     9901 tcgattgtct tcataatttt ggcttgcata actaatgctc agatgttttg gctggtattt
     9961 ttctcctata accttgccgt tgaatgcccc cagaagataa tggataatgg atgactttcc
    10021 tgcaccgtta ggacctgaaa tcgccacccg ctgatgaggc tcgattgtaa aatgaattgg
    10081 ctcgaataac agattttcat accctaattg aagatcttct acgcttaaaa gtcgcttatg
    10141 gtgagacgct tggctattca tcgtcaaaga atcgatatat tcgatatctt ttaatagttt
    10201 ttctttctcg ctgatctggg tctccatccg attcacgatt gctttggatc gtttcatcgt
    10261 ccgtgcagca tcagcaccca ctgctccttt attcactcgt ctagattcag tatcgatgaa
    10321 tccgacttgt ttctttgttt tatctccttc tcgggaacga gaccattcgg ctttttcagc
    10381 tgctgttttc tttagcctac tgacttcttt tttcaatttt tcattttgag ccatttcaaa
    10441 ttcatcacga agttttttct gttcttcata gatagagaaa ttcccttgat aaagttccag
    10501 ttgacttttt tcgattgcta aaacatggtc cactacttca tcgataaatc cccggtcatg
    10561 gctgaccacg atgaagcctt gttttttctt tttcaaataa gccgctactt gttttctacc
    10621 agagatatcc aaatgattcg ttggttcatc gattaacggg aaatgagtgt catccacaaa
    10681 taaaagtgcc agtaggactt ttgtcttctc tccccccgat agtgtgctga attctctcca
    10741 taagatttca ggatctgttt gcatcaattg gagctctctt tcgatttccc atatctcaaa
    10801 atccgtaata tcatttaaca cgtaataggt taaacgttct ttatcttttg tctgttgcgg
    10861 gaaataggca aattcttgct gatggattac ttgcccttga taaggtagtt tgttttgtag
    10921 aatattcagt aaagttgtct ttcctcgacc gtttcgtccg ataagtccta gtttccattg
    10981 tgtgtcaaaa tttagatttg cttgttcaaa taataatgtg ccttggctgt cgtagccgaa
    11041 tgtcagattt tttatttcga ttttagacat tttccatcac ctcgtaaaaa aagaccagtc
    11101 ctattttcag aactggctaa agaggatgca agggttggat acacacaaaa agacccatac
    11161 atcgaaaaaa ccaagccaat cccgaaaatc tgcacactgc ttccttgtct ccacaaggta
    11221 cagtctgaat gcagctttca tcaatcgact taatttttca atgcacggat ccctcacttt
    11281 gtcctatatt tgaaattacg atagcataaa gaaaatgatt ttgtcaacta cttcgggagg
    11341 atggtgaaaa atctgctaag tgtctgtcct aagatttttg ttttttctaa tgtttgcctg
    11401 tgttccattg cttcttctaa acctattgga cccaaatgaa tacttaagac aattgggaga
    11461 aaatcagaaa gtccttctag ctcttggtct ctacttccgc aaatagcgat tattggtttt
    11521 cgatattttt ttgcaagcac tgctacaccg tatggaactt ttccgtggat cgtttgctga
    11581 tcgatccgcc cttctcctgt aatgatgaca tctgcttgtt cgatcttttt ttccaatcca
    11641 gtgatttggc tgactaaatc gaaaccagaa accatcttcg ctcccaacaa aaaaagggct
    11701 ccaccaatac cgcctgctgc tccacttcct ggaatatcat ctaaatccac ctcccagaaa
    11761 tcttttattt gctgagcaat ctttcctgct tgtttatcta agaaagctag cgtcgtatct
    11821 attcctcctt tttgtcttcc aaattgccaa gcagctcctt gttgacctgt atatggattg
    11881 gtaacatctg cagcgataat caattttact ttagaaacaa gaacgtttct tcgatcaaaa
    11941 tgaagttttt tagtagataa taaaggattt ccttctgtgt acccttctaa agaagcaccc
    12001 aaggattgga gtaatcctag accaccatcg ctacacccgc ttcctcctaa agtgacaata
    12061 atttgttcta cttcttgaag cagtgcatct ttaataagtt ctcctaaggc ataactggaa
    12121 gcaagtcgga tagtttgatc cgttggttta tcaagtagat ctaaccccaa tgcttgtgca
    12181 gattcgatga ctgcggtgtt ttttccttgc caagttgtca ataaatagct gatttttcgc
    12241 tgacggaata agagatccat cccatcaatg gtacgccatg ttcccctgag cgcgtaatag
    12301 attgcttctg cagtattttc tccgccatct gcaatcggca cattgatttt tcttccttta
    12361 cgatcttccc agccatttag aactgcctga tttagttcaa atgaagaagc acttccttta
    12421 aatgaatcaa ttgccgccaa aatatccatc tgtatccctc actttcttct taagtaagac
    12481 actttttttc atttttttca aacaaaacaa tgctattttc ttccattttt ctatatacta
    12541 aaagggaact cattgaataa aggagagaaa aaacatgaaa atcgcaatag ctggggccgg
    12601 agcaatgggc agccgaatcg gattgatgct acatcaaagc ggaaatgagg tcctcttgat
    12661 cgatcgttgg cctgctcaca ttgaagccat tcgtacaaat gggttgattg ctgactttaa
    12721 cggtaaagaa gtggtcgcaa aactgccaat ctattcacca gaagaaatca tcgaaagcaa
    12781 cgaacacgtg gacttgatcg tagcattaac aaaagccaat caattagatg atatgttttg
    12841 ttcgatccaa tccattatta ctgacaatac ttatgttttg tgtttactaa atggattagg
    12901 tcatgaagat gtactggaaa aatatgtgcc aaagaaaaat atcttatttg ggatcacgat
    12961 gtggacagct ggtctagctg gtcccggaaa agtcacattg ttaggtgatg gagaaatcga
    13021 actagagaac ttggaaccag aaggcgaagc atttacaaaa aaagttgtag aagtctttca
    13081 agaagcaaat ttaaatccga tctatagcca taacgttcgt tattccattt ggcgaaaagc
    13141 ttgtgtaaat ggaacattga atggtttatg cacgattttg gattgtaata ttgctgaact
    13201 aggcgcgcaa aaagcggcag agagcatggt tcgaacaatc gtatctgaat ttgcttctat
    13261 cgcagcaaaa gaaggaatca tactagatca agaagaagtg taccaacata ttgcttctac
    13321 ttatgatcct gacaacatcg ggttgcatta cccatctatg taccaagacc tgatcaaaaa
    13381 ccatcgtttg actgaaatcg actacatcaa tggtgccatt tggcgaaaag gacaaaaata
    13441 tgatattgct acaccatatt gtgccttttt gacccaatta gtccatgcaa aagaaggaat
    13501 ccttggcgca gaataaaagg ctctctgatg agaatcagct gaatcagcag ctggttctct
    13561 ttttttaagc ccaataaaag atcaaaaaga aaacacaact ctcatgatgc cataagaatt
    13621 gtgcttgttt gtttcagtac ataatctctt caaaatgtag gttttttatt tgttttcaac
    13681 agaggagagg tcatattcgt attgctcata aatagtggaa tcgttagtga taaatcgttt
    13741 tgcccaattt tctgcatcat aaaattccaa tagctctgat aggattggct taaatggtgt
    13801 atgcagaaat tccggtaatt catctaaatc acgttctcga agcaaaaaaa tattttcagg
    13861 acgataaaaa tgataatgag caatcgcttg attatccgtc actagtttct tttgaaaata
    13921 catggattca aatgtccgca aagtcactcc ttgctgaccc tcccgcaaca gttccagaat
    13981 cccgcgcgat tcccctgttt ttttcaggta ctcttcataa gtaagatatc caggttgttc
    14041 attccctcga tgtggaagaa tgaaatagtt ggtcgtaaca tctcttttta taaattcctg
    14101 cttatagctt tctgctcgtt cttttctccc attattcgtt gcaccaaaaa atagatccgt
    14161 ctttggttcg ctagaagaaa aattcatatg tttcgaataa aatgaactat tatgtttcag
    14221 cccaagttct tttgcttcca aaaaatcaaa atgataaatc tcatcgattg ccggttcatc
    14281 ttgtgcctgc ttcagcatcg cctcgtgttc tgctttgaag tgattccaaa aaaataacac
    14341 aatttttgca ttggtaaatg ggcgcacgcg tcgagccatc tccatatcaa atccataatc
    14401 taaaaaaacg atcagctgat aatttgccaa ctgttgtcta gctgatttaa tgaattccga
    14461 ctgtagtaaa tcttttccgg accaaacatc taaagagcgg atggaaggca aaaaataaag
    14521 tgatttattt tttgcaacta gcagtacgtc atttttgttc atcttttccg cctcactttc
    14581 tctgtcactt tttcctatga tagcctgttt aaatagtaaa aagccagtaa aacgtttcct
    14641 atatttgtat gaaaatttaa catttgtatg aaaatatgat gaaataaatc attcttctat
    14701 taaaattcgc ctaaaagttt tctgaatagt tgtaattgtc tgaaaatttt ttatcattag
    14761 tcattgttaa atattgctat ttattcttaa tataaatttt gattgtgaat ttaaaagaaa
    14821 gaggtcattt atggaagata aaaaattgaa aaaacaactt agctccagac atatcaccat
    14881 gttagcttta ggtggagcaa tcggtgcagg tctatttaaa ggaagtggcg aagcgattgg
    14941 gatcgccggc ccttctgtat tgattgcttt tttgattggt gggctgattt tatatatcgt
    15001 gatgaaaggt ctgggaaaaa tcgttttaag cggtggcgac acgcatcacg gattatctgg
    15061 tttgatacgc ccttatctag gtgctcattc tgctgatttt actgattggg tctactggtc
    15121 tatgtggatt atcaatatca tcgctgaagc tgttgcagct gcttcctttt tgcagttgtg
    15181 gttcccgcac attccagcct gggtatttgt ttttatgttg gctgttttaa ctacgatcat
    15241 caatctttat tcggtacggt tattcgcaga aacagaatat tggctggctt ttgctaaaat
    15301 cagtgtcatt atcttactga tcatttttgc tacttatctt gtcggtcagc aaatgttggg
    15361 cacaggcgtt ttccctaccc ttcagcaatt gactgaccat ggtgggttta ctcctcatgg
    15421 tatgaaggga atcatcagtt ctttgcttgt agttatctat tcttacggcg gttctgaact
    15481 gattgctatc acggtaagcg aagcagatga tcctaaacgt gcgattccta aagcaatcaa
    15541 aggtgtcatg ggaagaatca tttcctttta catcattcct ttgtttttgc ttttgattct
    15601 ttttccttgg aatactttag caggcacgaa tgtcagtcct tttgtgatgg tatttgaaaa
    15661 aatgaatatc ccatttgcag cggatatcgt caattttgtg attgtccttg ctttgttctc
    15721 atctatcaat tcgggtgtgt atgcatcttc aagaattttg ttcttccgtt tgaaggatcg
    15781 aaaaggttcc tctagaaaac tagctgtttt aaacaagcat caagtaccgc aacgtgctgt
    15841 tttattttgt accagtgttc tttatcttgg tgtagctctt tcttattttg tcggtgacaa
    15901 attatttggc tatctggcag gttccctttc gtatacagta ttattgatct ggatcattat
    15961 cagtgcggca tcctttgtac tggcactaag aaaaggaaca ttatgggata aaggaatcag
    16021 cttttttgca ttagctgtct taggattgat tttccttggt atcctgttca cgaactccat
    16081 tggggtaact gtattgactg gcctgcttta cctgttcatt tatttcagtt atcaaaaaaa
    16141 gaatgatgcg ttcgtattga cgaatgaatg aaatcgatag aaaattttat tttatttatg
    16201 tggaatagat ggagctattg aagaaaggag ttgtgacaaa agtcttgttg caactccttt
    16261 ttccgaataa acagtctcat gacctcttgg taaacggtgt tcaaaaaccc tctgtgcaaa
    16321 ataattgatt gttctccatg ctcatgacat gatagaagaa aggaatgaaa aaaaggagtt
    16381 tgttttaaat gaaaaagtat tggaagtttt tgttgatgat cggtgtttca acggtagtta
    16441 tgtttggtat gatgtacttg aatgtctatg cgctcgatca tatcttcttc agtcgtacac
    16501 gagtattcat ggcgttgatg atgggtgcag tcatggcagt catcatgctg ttgttcatgt
    16561 ggaaaatgta tgaaaacaaa aagataaatg ttatgatctt agccgctagt cttcttgttt
    16621 ttgccggttc cttgtttatg gtacgaagcc aaactactgt caacgacaca gcttggatga
    16681 aggccatgat tcctcatcat tctatcgcta tcctggcaag taaacgagct gatttaaaag
    16741 atcctgaagt aaaaaaatta gcggaagaaa tcattcaggc acaagaagaa gagatcgaca
    16801 aaatgaaaaa aatgatcaaa gaaatggaat gaccattatc cgtccaaata aaaaaagagg
    16861 atgttccaga agttatcagc ttcaagaaat aagaagaagc tacttctgga acgccgtgaa
    16921 taaggggttg tgaaaaagct gccctgcatc aagtaataag aacagccaaa caaaaatagc
    16981 ttctcctatt tttcgtttgg ttaggcttat taccgcagat gcaagctttt gaacaccgtt
    17041 tattaagagg ttgtaaaatc agcgttctga cctgagtatt agagagacaa atggaaaaat
    17101 agttcctcat attttgccat tttttgagct aataccgagg gtcagctgat tgaacaccgt
    17161 ttatcgagag gttgtgaaaa agtcgcttag tttcgcgtat taagaaaaat tttgtgaaat
    17221 ggctttccac atttttgtat aaatttggct taataccgag aaactggctt ttgaataccg
    17281 tttattcgta aaagggattg tgacaaaagt cttgtcacaa tcccttttta tgtttttatt
    17341 gttctaattg cgctgtcttg cttactgctt cttgcggttt cacaaatttt tttgagattc
    17401 cccaacctgt gaaggcactg accatcgaaa acacaggaga aagcaaactg aaaaatacga
    17461 atggcaagta agtgagtgta ggaataccaa atgtacttgc tacgaaactt ccggcaattc
    17521 cccaaggcac taagtagttg attactgttc caccatcttc tagcgttcta cctaatacag
    17581 ttggatcaaa tcctgctttt tcataagttt ctttaaatgc attaccaggc agaataacag
    17641 ataggaattg ttcaccaata aaaatattta ctccgatact tgtcatcaat gttgtaaaaa
    17701 tcaaatttgg tgtgttcgtc atctttcttg atactcgttc catcacggtt gagatcaagc
    17761 caaattcgat caacaatcca cctaatgaca aagttagaat aatcaatgac acagtaggca
    17821 tcatactttc gattcctccg cggctaagca gtgaatcgat ttgttggttt ccagtatttg
    17881 aaacaaaccc tgattcgatg accccagcca acttcgttaa ggaagtttgt gggttttgaa
    17941 taaaaatcat tcctactgct acagcgatat tcaacaaaat cgttaaaatt gccggcacct
    18001 ttttccatgc acacagtaac attaaaaata aaggaatcag tgaccagatt gaaatagtaa
    18061 agtttgcttc tagaacatca gtcacttcac gaatagatga aagacttgcg gctttacttg
    18121 tgtgtcctaa aatcatgaat aaaaagaaag aaacaacaaa tgccgggaca gttgaccaca
    18181 tcatatgctt gatgtgtttg aacaaatcgg catcaacaat agctgctgct agatttgttg
    18241 attcggataa tggagacatc ttatctccaa aaacggcacc tgaaacaata gctccaacaa
    18301 ccagcgctgg atttaagcct agtgttgtcc caataccgaa aaatgcaatc ccaatcgttg
    18361 acataacagt aaaggcactc cctacagcgc tacctacgat tgcacacaca acaaatacag
    18421 aagggacaaa ccactggaca ctgatcaatt tgaacccaat gaccattaga gttggaatga
    18481 tccctgcttg tatccataca gcaatcaatg aaccgactaa aataaaaata aagattggga
    18541 tgattcctgg tttgatgcca ttgatgattc cttcgtgcag ccaatctgtc gggtatcttt
    18601 ttatcactgc atacaacatg accattccga tcgctgctaa gatcgtgata ttaggtgaga
    18661 cctttaatcc gacaacgcca atcgcaatgc ctaaaacaat aaccattaat acaagtgttg
    18721 cttctaaaaa acttggtgtt cctttttttc ccatgataat ctctcctttt ttagttgttc
    18781 ttatgttcta aaaaagttaa gatatcggat tactccgccg caattcatcc gcgattcctc
    18841 ctttataaaa ataaaaagac ctgttttaaa ctaaggacga atgactccgc ggtaccacct
    18901 taattaaaaa cagatctgtt tttcactttc aaacttttat tcaaatgtat ggactttcca
    18961 tgtaattcgt caattaggct tgatcggttc acagcgacca ccgactttct gaacaaaaca
    19021 cctaaccgct actgcgtgaa aagttgactt gtacgaagtt taccttccat aagatcattt
    19081 gtcaatgaaa aagaaaatat tttttcattt ttctgaaaat tatttttata actttcacac
    19141 acaagattat tttttactag aaagtagcgc cctcttgttt ttttcttgct actatttctt
    19201 gatgttcttg cttgattctt tctaatagct ttggctcttt caacagatca agagctgtat
    19261 tggcgagtag ttctgctgca atcgcaatag aagcaaggcc tttgtcactt ttagcagcag
    19321 ctttgaattc ttctgtgtgt ccggcaatat atgtctcaga gattgctacc gtaggctgga
    19381 ttgttggtat gacttggctg acatttccta catcagaaga accgagactt gttctttgtt
    19441 ccgtttctat ttcttcatct ggaacacctg cttcttttgc atgctggaag aataagtcat
    19501 caaaagaagg agtaacgatg acatcatcaa ctgcattttg gaacaatcca aactcaaaag
    19561 tcgtgcccgt acttatcgca gcacctcgta cgatattttc cactttttca tatactttat
    19621 ctaatgtttg ccgatttcct gcacgtaaat agaaacgtcc agcagcgtaa tctggaatga
    19681 cgttggcagc tactcctccg tctgtaatga tcccatggat attgacatct tttggcaatt
    19741 gcaagcgtag agcgttgatt ccattaaaca cttggatcaa tgcttccaaa gcatttactc
    19801 ctttttcagg tgctgctgct gcatgggaag cgacaccgta aaatttgatg tcgactggat
    19861 cattcgctaa agattctgtc gttttcccat aacgaaaagc tggatggacg cataacgcta
    19921 catcgacatc ctcaaaaaaa ccttctcgaa caaagctgcc tttagctgat ccgttctcgc
    19981 ccccttcttc ccctggggtg ccatatacac ggatttctcc accagtttca tcaatgaatt
    20041 gcttcactat gctggcggct aatacggagt aagtaccaaa caaattatgc ccgcatgcat
    20101 gaccaatacc tggtaaagca tcgaattctg ccaaaaaggc aattgtggga ccgggtttat
    20161 tggaaatata acgtgcatca aaggctgttc ggtgtccagc tacttctttt tctacccaaa
    20221 acctttcttt ttctaattgt ttaatcaacg ctgctgagga ataaaactca tagttactta
    20281 cttcaggatg ttcgtggata tctagagcaa gtgcttgata ttctggtaaa cgatattgga
    20341 ttagatcctt caattggttt gttgagattg ttgttgtcat aaaaaattcc tcctatgcta
    20401 gtcatttttc ttattttctc ccgaatgttt cccatgcagg cacgcttgat ccttttgatg
    20461 ttttctcgat tactttgact gtgtcttctg tttgataagc gtctactatt ttttgatacg
    20521 ttttattgtt ttcatcttct tttcttgcaa cgatgatatt cacataagga cgtgcatggt
    20581 catccactgg ttctaagaag atggcatcag aagcaggatt aaatccagca tctacagcta
    20641 caccgctatt gatcactgaa atgtctacat ctgacaaagc acgtgctgtt tgggaagcat
    20701 ctaattcaga aatgtctaga ttttttctat tctcggtaat atcagaaaca gtgggcgctt
    20761 gtccttttgc cttatccact ttgatcaatc cagcagtttg caataacaga agagctctgc
    20821 cgccatttgt aacatcatta gggattgcta cttttgctcc gtctttgata tcagctacat
    20881 ccttcaaagt gttagaataa attcccagcg gtgcattgac agtatttccg atcgatacta
    20941 aatcagttcc gtgttcttta ttgtaattgt ctaaaaagaa ttgatgttgg aaagaattca
    21001 aatcaatcga tccatctgct aaagccacat ttggttgatt gtaatctgta aatttcacgt
    21061 attccaaatt aatgttctcc tttttcaaac ggtctttcac gttgtcccat acatctgtat
    21121 cttctccaat aatccctagt tttacgatag tttctttttt gtcagttgta tctgcttttc
    21181 cttggctaca ccctgccaac caaataattg ctacaaatgt aatgactaca aaacgaataa
    21241 tttttttcat tttttctcct ccactttcaa tgtgtaattt ttttaatcag ttgattactg
    21301 ataaattgac ttaaaaaaac taagattaga atcaataatg tagccacaat cgttacatct
    21361 gtttggaatc gattataccc tctcgatata gcaagattcc ctaatccgcc tgcacctact
    21421 gctccagcca tggtagtcag tccgatcacg ttgatgatag tcaacgccga gacccgaatg
    21481 ataccaggca aaccttctaa caaatacaca cgtaaaatga taccgattgg actggttccc
    21541 atcgcttctg ccgcttcgat caccccagga tcaacttcta gcagtgcgtt ctcgatttga
    21601 cgagcaaaaa acggaacaac tccaaaaatc aatggcacta aagctgcttt cgcaccaatc
    21661 gtcgttccaa ctaagaaacg agtagtcaat gctaaaagag aaagcaagat aatgaaaggg
    21721 atggaacgaa tgatattgat cagcttatca agtatttcaa atagcagacg gttagctagt
    21781 aatccattag ggcgtgtcac tactaacgtc acacctaaga tgattccaat catcccgcca
    21841 atgaatgctg tccaaaaaga catatatagt gtttgcttcg tcgcttcgac aaattcatcc
    21901 ggaatcaaat aaacattggg caaatatgtt ttaaagaaat cagtcatttt atcttcctcc
    21961 ttcgatcact ttgatacgac tatctaaatc gtttttttgt aaaatattta tttttacacc
    22021 agatttgatc aaataatcca atgctttttt ccgctgtttg gtttctccag ctaaagtaac
    22081 gatcaaactc cctaacggcg tttcttgtaa taactctaca ttgccatata aaatattcgc
    22141 tgttacttga tatttgctgt acagatgagc gattagaggt tcgttcgtct gatttccaat
    22201 ataacttaat tccaccagcc atttattggc gatctgatcg gcaaaagcag aatgggcaat
    22261 gatcgtttct aatgcttggt caagatgagt agctgttcga ataaaatctt tggtcaattc
    22321 ttcttcagga ttgctgaaga tctggatgct gctacctttt tcaacgattc ttccatcttc
    22381 cataaccgct accttgttgc agatttcttt gacaacttgc atctcatgag tgatcaggac
    22441 gattgttaaa cctaactggc gattcaattt ttttaacaat gcaaggatct gaagggtcgt
    22501 tttcggatca agtgcactgg ttgcttcatc acataataat accttaggtt cattcgccaa
    22561 agctcgtgcg attgctactc gttgtttttg tccccccgac agttgtttag gataagcaga
    22621 tgctttttct tccaaaccga caagttccag tagttcattc actttttgac gacgttcctg
    22681 tttcgatttt ccagaatact ttaaagaaaa atcaacgttg tcaaaaatag ttcggctttc
    22741 cattagattg aaatgctgaa agatcatacc gatggccttt ctttcttttc gcaattcttt
    22801 gggagagagc tgactcagat tcgtctgatt gacaatgact tctcctgctg ttggtttctg
    22861 cagcaaattc atcacacgaa ctaacgtact tttccctgca cctgagtaac cgacgattcc
    22921 ataaacatcg cctttttcaa tcgttaaatc tacagaatct actgcctgta tctctttttc
    22981 tttttgtttg aaacatacag aaacatctcg caattcaatc attaaaattc ctccttatct
    23041 aaaaaaagcg tcctcaagaa aatgaaaatg tcattttctt gaggacgctt ttttgcgtgt
    23101 taccacctca tgttcaagct gtgttcacac acaactcctc ttcaagtacg atcatactct
    23161 agcaagatat cggtcgcagc cgtcatcgcc ttacatctat gctcgggatg aattgctcga
    23221 tggccatttt ccaatagtcg ttccttgctt cttctcagct accgaagctc tctgtcaaag
    23281 gttcttctat cgtacttacc atttcaatgc aaataatatt caaaaaaaaa gtccttttac
    23341 taacataaac tatgtcagta aaaggacgac gtatcgcggt accacctttt ttcggaagtt
    23401 tccttccctc aagcccaaca tctcaaaaag agagattggc gttcgtttta acggtcgaac
    23461 agttccgaat ttgcctactt atcgacaaat tattctccaa ggccattttc agcttttctt
    23521 acttgactct tctcaccagc cagagcctct ctgcaaagtt tccaaactta ctttcctttt
    23581 caacgaaatc gatattttgt tgttgggatt aatctacatg aggaaaactg aaaagtcaag
    23641 tacgaaattc aaattatttt ttctatattt atttttctgt ttttttattt aacatttcaa
    23701 taacagttcg aagatctttt ccttccgcaa gaagtttcaa tttttccttt tcttcgacgg
    23761 tataatttcg gacaaaactg gaatcaggta tcaaaacaac gcctaatcct gctcgtgaag
    23821 cagctgttgc tcctactaaa gaatcttcca ctgcaaaggc tgaactagct tctaatcctg
    23881 ttcgttccaa agctgtcaga taaggaatcg gtgaaggctt gttctccgac acttcgtctc
    23941 cgaatgtaaa cgtgtccaag taatcagcta atttaaagtg atccaagata tctgttgctc
    24001 ttttcgtaac agtggtcgta gcaatgccta gtttcatatg acgttctttt aagtctgcca
    24061 atatttcttt tgcatatggt tttaagtgga tggctccgct tgtcagctgt tgataaaaat
    24121 attcttcacg cttcgctcgg acttcctgta ctttttcagg gctacctgct gctttcacta
    24181 aaatatcaaa actttgtttc cagttttttc cgccccaagc gtcaacgatt tcttttggga
    24241 tatggatatc aaattgctga aatccccaaa gccagccatc acgatacgtt ttttctgtgt
    24301 caactaacaa accatctaaa tcaaatattg cacctttcat ctatacatta atcctttcca
    24361 aaacaataca catagtttag cacgactggt ccaaaaagaa cagaagcaaa gaaccagcct
    24421 tctcgtttat aagagttctt ggaatcgacg gatatagatt ttcttcacag ctgtcacaag
    24481 cgccagataa gcgatgactg tagcaaataa ccataaccag taattgccag gaagtggcat
    24541 caagcctaat tcagcaccaa aacttgtaaa aggaaggaca gaaccgacaa taattcctaa
    24601 tgtagtgata acaaacatgg caaatgttgc gttgctttgg ataaatggta ctttcggtgt
    24661 acgcagtgca tggagcacta aggtttgtgt ccatagtgat tcgacaaacc atcctgcatg
    24721 gaataatgcg atgaaaatca ctcgctgtga actatccaat gtatggaaac ttccgcccac
    24781 tacagcagga caaataacaa aatacatcaa caagtaagta gtaatatcaa atatcgaact
    24841 tgttggacca aagtaaacca tgaattcccc aatactagat gcattccatt tttttggctc
    24901 gtccaaatat tctttatcca tccgatccca tggcaaggaa atgcaggaaa catcatagat
    24961 cagattcaaa aacaaaagtt gtaaaggcag cattggtaaa aatggcagga acgtacttgc
    25021 aatcagcacg gaaaacatat tgccaaaatt agaacttgct gtagccttga tatatttcat
    25081 gatattccca aaagtttctc gtccagaaag aaggcctctt tccaaaatcg tcaaatcttt
    25141 ttctaaaagg atcacgtctg cagattcttt cgcaatatcc acagctgtat ctacagaaat
    25201 accgatatca gccactttca ttgcaggagc gtcattgata ccatctccta aaaatccgac
    25261 agtatgacca tttttacgta aagctgtcgt caaacgtgct ttttgctgag gattcaattt
    25321 tacgaatact tcatggtctt cagctacttg tgctaattca tgatcactca tttccgagat
    25381 tttctcaccg gtaaccaatt cattgatctc tagacctact tgacggcaca ctgaacgtgt
    25441 aactaattcg ttgtccccag tcagaacttt tacagctaca ccatgttctt tcagagcttt
    25501 caacgcttgt ttcgttgttt cttttggtgg atcaaggaaa gcaagataac caatcaaaac
    25561 catgtctgac tcatctttga ctgaaaattc tccaacgacg cttggattgg tcttttgtgc
    25621 gacaccaatc actcgtaagc catcttcatt aagtgactgt acttttgcaa gtacggcttc
    25681 ttttcgttct tttgttaatg gtgtaacagt accgccaaga tcaataaatt tagaaatgtt
    25741 cagcatttct tcaatcgcac cttttgtgat catttgtgtt ttaccagctg gatcagcaac
    25801 cacaacactc atacgacgac gttcaaaatc aaaaggaatt tcatccactt tttgataatt
    25861 gatcttatct gtatctaaag tttctgttgc ttcatcaatg atagccacat ctaacaaatt
    25921 tttcagccct gtttgatagt agctatttag atacgcatgg cgcaaaacac gatcatcttc
    25981 atttccttca caatccatat gatattcaag aatgatttta tcttgtgtca atgtccccgt
    26041 tttatccgta cataacacat cgattgcacc aaagttctgg atggcattca aatttttgat
    26101 cactgttcct tttttggcca tcacacttgc tcctttgacc aaattcgtcg taacgatcat
    26161 tggaagcatt tcaggtgtta gaccaactgc tacagatagt ccaaaaagaa aagcttctag
    26221 ccaatcccct tttgtaagcc cattgatgac gataactgct ggagccatca atgacataaa
    26281 tttgatcagt agcatggatg ttttatggat gcctaattca aagcttgatt gaattggttt
    26341 ttcagatagc gtttctgcta catgaccaaa tagtgtttca tttccaacag aaacaatgat
    26401 tccttccgca cttccactga tgacattact tcccataaag acaagatttt cgtaacttgt
    26461 ttcgctttgc tgatcgtctt cacatacttt cgcatgcttt tctactggat agctttcccc
    26521 tgtcaatgct gcttgggaaa tgaataaatc ctttgcggac aataaacgca tatccgctgg
    26581 tatcatatcc cctgctgaaa gccgaacaag atctccacag acgatttctt ccataggaat
    26641 ctctgtgtac tttccattac gttttacagc tgccgttact ttcacaagtg atttcagttt
    26701 ttcagccgct tgattggaac gtacggactg aatcaacgtc attgtcccgc tgacgataac
    26761 catagtgaag ataatggcta caccgaaaag atctttatct ccaggagctg ctaatacata
    26821 ttccgtgatg aatgaaataa ttcctaatgc gatcaacact aatgtaaatg gcgtgatgta
    26881 tgctttcaat atttctacaa tgaatggtgt ttttttgcca tatgaaatcg cattttcacc
    26941 gtaattttct cttgaacgtt cgatttgttc ttctgtcaat ccatttgctg atgcatggaa
    27001 tagttcaaat aattcttgtt tcgtttttcc agcaaaagct gcatagattt tttgtgtatc
    27061 tttctttttt tccatctcaa tctctccttt gtgtccaaaa gacagctgtt ctcgctgctt
    27121 ttggtcttta gctattcatc ggatcgatag agaaaaaact gaaaggggct gagaacagat
    27181 agataatagc cctggccttt cctctagatc cttgtttttc gaatgactgt catccatttg
    27241 ttctcatctc ctttactaag taattttaat tcatgacttc caatcatttt tcgaatagtt
    27301 atttttccaa ttagaccacc tcctttttat ttttcaccga tggggatttg cggcaacaaa
    27361 aaaacctctc gccaaatact cagcgaaagg tttgaaaaag catattaaaa aaagcttctc
    27421 agatctcatc gttgagtttt gacactgtac aacgtaaaaa gcagatacct gcttttagct
    27481 accttatgaa aagccttatc tcgacaattc ctgttctacc cattggcgtc tctcgacgtt
    27541 tttgggcagt agcctatgtt tgtataggag cctcacctaa caaatcttat tcggttttcc
    27601 ttcgttaata taacaactaa aaaagaggat gtcaaatcaa ttttccatgt ttttcatact
    27661 ttttttaaaa tacacacgtt atattcctgt ctcacgcggt tttatttgtc tcattttcca
    27721 cctcccgcta taatagaaat atagtaggaa acgaggtgct gttatggaaa gaacacttgt
    27781 tattatcaag ccagacggcg tgagacgcca tttagtcgga agcatcatcc aacgttttga
    27841 agcaaaggga ctggccattg ctgaaatgaa gtttgaaact atgactcctg aattagcaaa
    27901 agaacattat cagcacttga ctgagcgcag tttttttgat gaactgatcg attacatgac
    27961 ttccggtcct gtcgtttatc ttgtgctggt cggcgaggaa gtgatcgata tcgtccgtaa
    28021 gatggttgga gcaacaaaag ctgccgatgc tgttccaggt acgatccgag gagactacgc
    28081 gctgccgggg actgaaaaca tcattcacgc ttctgattcc cgtgatgctg cggtaaaaga
    28141 gatcgcccgc tttttcccgc cattcgatat aaacaaaccg tctgaaaaag cggcgaagtg
    28201 atacaaattc taaactgctg gtctagttgc tgggttcagc aatggccagc agttttttct
    28261 ctaaggacct ccgttgattc tttcctaaca tatattcgag cactgtgaag aattcttggt
    28321 agtctttcgt cttttcttcc cctaaagcag cagaaatcaa tctttgataa taatctgcca
    28381 tcaatgtttc atagatcact gtacttcttt ctttatgtgc taagctccgt ttcatatctt
    28441 cattcacact acgtgccttt ttcaaccgac cattttctat ataaaacgaa gtcaggttca
    28501 ttaaaaaagt aaagagatac tgctcatgat tgttcaactg tgctaatcgt cgcattcttt
    28561 ttttgatttt caaataattg ttctcaatga accgatcact gaatatccaa ggaaaatcag
    28621 ctagaataga tagttcaaat tgaccatagt ctggtatctg catcaagtat tcttcaatga
    28681 ttcggcattc ataacgtaaa aattcaaatt ctgtctcaga tacttctgtt ttttcgacca
    28741 tgtgaagatt caaaaccaaa taatacagat cttctgtttt cttaaaatgc ctacggttat
    28801 tgctgatctc tttataagga tcaaagctgt cttcttgtac ccgatctagc attcgtcttt
    28861 ttttctttaa ctttattggt tcatccagct ggtttcgcat ccattcatat tctgcaagtg
    28921 tcatgttcat tcgctctaaa aatgatctca atgttacaaa tgacattttt ttcactgaat
    28981 ttgtctcaat cccgactaga gaagtcttaa aacagattcc ttccgctaat tgggactgtg
    29041 tcaacttctt gttgactcga agtttcttga tcaattcacc atcatacata atagttctcc
    29101 tttttaattt aaatttttcc acattcaata aatagatacg ttaaaaagga aaaatacacg
    29161 aaaaaaataa aaaaatgttt ttttcataaa aaataccaac cttcaagcat tagaatgttg
    29221 tctaactact gaaggttggt ttgattgttt attgattatt tttttgctgt tcaacgtctg
    29281 ttcttgttac tggatataag ttggttgttg ttttattacc attttttgaa aagacacttg
    29341 tcgaatgttc gcctttttgc ttttcgattg cttcattacg ttccgcttca tttttatagt
    29401 catatttttt cggatcaatc gtctcaaatc cgtttggcac ataaaaccgc aagagatttt
    29461 cctgattcag cttatctgaa agacttaacg cagtcttgac tttttcctga tctttggaga
    29521 tttcctcatc gattcctgct gctttcgtat cgatgatttc tcctgtctga ttattgtaag
    29581 cttttcctcc taggacggtg tatttgggtg tcacaaagtt cccatttcga aaagcaacta
    29641 cttgatcatg ctgagaagat aataagtctg taccaaaatg aagataatct ttatcatcga
    29701 ttcccaatag atgtagtaat gtcggcaaaa catcgatttc tccaccgtat tcatgattga
    29761 ctgtcccttt agtataacca ggcatatgga tcatcaatgg cactcgttgc atctgtgcgt
    29821 tgtcaaattc atcccatgta tctggatctt taccaagagc gcttgctaaa tctttattat
    29881 ctgtattcga gatcccaaaa tgatccccgt aaatcacaaa gattgaattt tggtaaatac
    29941 cagatttttt caaatacgta aaaaattgtt ccaatgattg atccagataa tgtgccgttc
    30001 gaacataatt atctactgtg ctattgccag tattcaaaga tggaaagtcg aaattcttgt
    30061 catccgtata ataaggcgtg tggttggtta cggaaagaaa tttcgtgtaa aacggctgtt
    30121 gtagatgctc aagatattgg gcagattctc tgaataaatc tttatctaat atcccataac
    30181 ctaacgtttc gtcggattca tcaaaataag atcgatcaaa gaaattgtca taacctaagt
    30241 ttttatatac atgatctcta ttccaaaaac tagctacatt cccatggaaa acagcgcttg
    30301 tatagccttg cttttgtcca aggatcgctg gtgcggcttg aaagacattg tctgacccaa
    30361 gttctgtgaa taatgagcct tgaggtaaac caaatgtgcc agtttccaac atattttcag
    30421 catcacttgt ctttccctgt cctacttcat gaaagaaatt gtcaaagctg atcgttgctt
    30481 gattctggaa aatactattt aaaaacggtg tgacttcttg tccgtctacc ttcatattaa
    30541 tcaaaaactg ctggaaactt tctaaatgga gaacgatcac atttttccct ttagcgatcc
    30601 caaatgtttc gggatttggc tctgcataat gtttctttgt ataatctaaa acttcatcaa
    30661 tcccattact gcttgcatgc gcgcgaacac tgctagtcat tcctgttttg attccgtcat
    30721 aaatagtata cgcatcgatt cctagatatt tgacaatata tgaacggtca aatgttcgct
    30781 gcagcaattg tggacggttg gcttcgctca gcgctagatt tcctgaaaaa ataagccctg
    30841 aaagacaggt aacagcgata gccatcggtt tgccgacagg gttgcttttg ataggtattt
    30901 tcttgacctt caaccaaacc agtagcccaa tgaacacagc gatatccagc cagtagatga
    30961 catcatgggg cttcatcaaa gaaaaggagc ttcctgacaa tccttgcgac actttcgaaa
    31021 agcctaatac agatttgact gtaatgaaat ctgtgaattc ccgataaaaa ataatattca
    31081 agtacaacaa aagcgtattt aaaatatcaa tgatcaaaag aatagctaac gctggctttg
    31141 gctttttaat atacaaagaa aggccaaaaa acaataaggt agtcgcaatt gggttgatcc
    31201 acaagataaa gtactggatc gtaccttcca cacctaatga aaaatctgca tagtaggcaa
    31261 tgatcgtctt cagccagaaa aagaaaacag ctgtcaaaac gattgctaaa cgattttggc
    31321 acaatttttt aagttgtgtc acgtatatca cttctctcta ttcacatttt ttcttatttt
    31381 gctcctgaaa aatgaaaatt tcctaaaaaa gttgttatct taagattttt ttattctttc
    31441 taaagattat tccgtccact tttcacagca taaaaccgct gcgatgtaag cgattaaact
    31501 aatgaagaga taaaagtctt gtggtgaccg cttcactcca cggtattcaa aagccagttt
    31561 ctcggtattc gtacaaaaaa agaggctgtg acaaaattct tgtcgcagct ccttatttct
    31621 tgatgcagga cagctttttc acaacttctt ccttaaacgg tgttctcctg ccaactcctc
    31681 ggccacaagt cacaatattt ataaaacatg agaagctgtt ttttgaaatt gttccttgtg
    31741 gctcagagtt aaacggcagg ctcaagacct cttgatacac ggtgttcaat cagctgaccc
    31801 tcggtattag attatgtcag gacgctaatt ttacaacctc ttggtaaacg gtgttcaaaa
    31861 gcttgcatct gcggtaataa gcccaaccaa acgaaaaata taaggagcta ttttttgaaa
    31921 ttgctccttg tggctcagag ttaaacggca ggctcaagac ctcttgatac acggtgttca
    31981 atcagctgac cttcggtatt agctcaaaaa acggcaaaat atgaggaact attttgccgt
    32041 ttgtttctct aatactcagg tcaaaacgct gatttcacaa cctctgtttt tcattgtcca
    32101 taggattgat attgtccttg tgatgactca ttcgtaataa ttgaggcttg attttcttca
    32161 cttcccgtta tcgtttgtcc actgccagaa tctgaaggac ttgttcctgt cgactcgttt
    32221 ttttgagaag agacagttgt tttcttgact tgttcatttg tctttttcca ttccgctaaa
    32281 cgatcggcga ccactttttt gtctactttt tcagaataag cggtgatcac ttttccattt
    32341 ttcaaacggg ctactttgtc gccatcatga gtcaaaagca aaacggtcaa atgcttgtct
    32401 ttaaattgat attgtctgag agaaatcgca ctaagtacgt catcgatatt aataaattga
    32461 ttttcttctt ttccttttgg caaataaatg tccaattcgc ctttttcgta attggcagtt
    32521 attttatact ccgcccacca ataagttgag aattcttttt tgaaattatc tactgattct
    32581 ttgcttgcta cgattttttc tgtttctttc tgagcaagat ctgctgtcat ttttcctgaa
    32641 aatgctgcgg ataaaataag cagtaagaaa aaaccgaata accaaaagag aagaaacggt
    32701 ctttttttcc tcatgctttc ctccactcct atttaatttt gactattcta ttatatacaa
    32761 aaaatgaaat agaaagacaa aaaagttgaa aaagatcgta aataattgaa cttctttttc
    32821 acaaaatggt aagaatggag aatttcacgc atttgctctc aactattctt tcttaagcct
    32881 caaatccgtt tttatctgat acgtctttga accaatgacc cgattttttg attgttcttt
    32941 ttccatcttg tgctaagtct actgaaataa agccatatcg attcttatat gcattggtcc
    33001 acgaccagtt atccatacat gtccacatat gatagcctaa acaattggca ccttcttgaa
    33061 tggcttgatg gacatatttc agatgagatt ggacaaattc gatccgataa tcatcgtgga
    33121 tcatgccatc ttctttgata aatcgtgctt cgttttctac acccataccg ttttcagaaa
    33181 taaagcagtc gatatttcca taatgatctc gtacattgat caaaatatca tagattcctt
    33241 gttcatagat ctcccatccg cgataaggat tcattttacg accaggcatt tcataattgt
    33301 cgaaataatc ctcaggcatt ggaccgtttt tagtatcgat tggtgtttct tttgctttta
    33361 cccggcgtgg ctggtaataa ttgataccta aaagatctac tgtattttct ttgataaccg
    33421 tcaaatcctc tgcatggatc acaggcatga gatcaagttc ttttactatc tcaatcaatt
    33481 cacttggaaa ctcgcctttt acagctggat caaggaatga acgattgaag aacgcatctg
    33541 ctatttgcgc tgctttaaca tcttcagggt ttgattcgtc tcttggatag cttggtgtca
    33601 gattcaagat gataccaata acaccacctt gctccatttc atggtaagat ttgatggcta
    33661 acgctgaagc caacgcttca tgatagccaa cttggatcgc ttttttcata tctgactctt
    33721 ctggataatg ccatcgatat aaataacctg cttcgactgg aacgattggt tcattatgag
    33781 taaaccattt ttttactttc gaaccaaaca attcaaaaca acttttggca tatttttcat
    33841 aggcttcaac cgtttctcgg ttcaaccatc cgcctttttc ttgcagatac atcggcatat
    33901 cgaaatgata cagattcaca aagggttcga taccgttttc aatcaactca tcaaaataac
    33961 gatgatagaa acgaacggct tcttcgttga ttgttccaga ttcatcaggt atcaaacggc
    34021 tccattggat agatgttcga aatgaattat gcccagtctg tttcatcaac tgtacatcct
    34081 cttgatactt cgtataaact tgcgaggttt tttcaggtcc tacttgatca aagaactttt
    34141 gcggttcttt tttgtaccaa taatcaaaaa tgttctctcc ttttccatcg cctgaaatcc
    34201 ttccttctgt ttgtgggcca cttgctgcag aaccccacca aaaatttgct ggaaattgat
    34261 attttttcat caaagcacct ctttttcttt tttagttcgt tttagttgat tccatgtatg
    34321 atattttcca tcacaatcac tttttcattt tcttcctctt cttttttgat tcgttttaac
    34381 agctgttctg ctgctcgttc cccgatttta tctgttggtg gcgtgatcgt gattttcgga
    34441 aggatactca gatcgttttt atctaaataa tcatagtgac tgaacgcaat atccttcccg
    34501 attctgacac cttcttgatt gaaacattcg atggcaccaa tcgacatatt gtaattgctg
    34561 acaaaaatag cagttgcccc tttttctaat aatgcttttg ccccgtaata gccgcttttt
    34621 ctagaatagt ctcctgtaaa gacctctaat tggatcgatg gatcattttg gaccgcttct
    34681 ttggctcctg ctaaacgttc tcttgctacg tagtctgttt gagtggcagc aataaatccg
    34741 atttttttat gtccttgttc accatgatga gcgatcactt ttgctacact ttctcgatca
    34801 ttcactaata ttgtatcaat acctgctggt ccttctggac aattcaatgc gataactgga
    34861 atactcattt ttgtgagcat ttcaaatcca gaccactctt cttcggataa gaagacaatc
    34921 agcccatcga tcacatgctt catcaggtat tcaatttttt gttcaatttt ttctggctga
    34981 tcggcaaacc cgcttaataa taagctatac ccattttctt cagctactct ttcgatccct
    35041 gagacaactt ccgacccaaa acggctggaa atcccgttta tcaaaagtcc aatagagaag
    35101 cttcgattat tcttcaaccc tttagcaatg atgttttctt tatagtccaa cgctgaaatc
    35161 gcttctgcta tttttttcat gttcttttcc ttcagttgct gaccattcaa gtaacgggaa
    35221 actgttccca ctgaaacacc agccatctta gccacatcac ggatcgatgc catacattct
    35281 cactcctgcc agttacattt gatttctctt tcttgttgtt cgattatgat gaccgcattc
    35341 tttgcatagt gttgcttgtc atcaatatcc atataactaa agtcttcagt agagcaactt
    35401 cctctcacta ttaattatac ttaaacaagt atttgaaccg gttcattttt aatatagcat
    35461 ttttttaaaa gattgcaaca cttttttaaa acgctttctg aaagtggcgg attttttgcc
    35521 tttttaaaat tttattctaa aatttactct atttgtgggt gttttgtgcg tttttctctt
    35581 ccatccgttt gaagttttac attccaatgg tataatttct ttatcctatc aaatggggga
    35641 agtattttga agaaattaat cgtactattt attttgtctg cgggactttt gacattgact
    35701 ggctgtgatt tgtttggcgg ctctgaccaa tcctcggacg aaacaaccga ttcttctgtc
    35761 ttaaaagcgg aaaaagcaga taccaccaac agtgtatata cgctaaaagt acgtaaagat
    35821 atggatttat ccgcgggaca gttgacattt acagataaaa aaatggaatg gacacgcacg
    35881 tatcagacac aaggaactga ttcttctgaa tcatctgaag aaaaaacagt gctgacagat
    35941 atcaagatca ctaccaaaga tgacgaatat attatttcag gaaaagaaaa taaaaaagaa
    36001 acaacagtca tatttacaaa aatcggtaat taccgtttga aggatgagga tggcaacatc
    36061 tacagtctat agtgccgtct gttggatctt cttttgtttc tccccttctt ttctgctata
    36121 gtaaagaagc aagatgattg taaaggagac gaaatggatg atcgatagtc ctgattattg
    36181 tacatgtaat aacaacaaaa atatccatac agaatttaat gaccaaggaa gcttgagcat
    36241 atgcgacaac tgtcacaaac tagtcaaaga ttcatttaaa acatttgaat cttatcctgt
    36301 tcaaaattat gtaaaaagta gaagaagata aacaaatcca agcaaaactc actatggctg
    36361 atttttatga acttcaaact cagcttcttc ctttgatcaa gcttcatcag taaaacaaac
    36421 agtggatcat ttcagtttac aaatcaaaga gtaaagattt atttatttca aatatttgaa
    36481 tataaaataa ccaaacgata gaaaggctta ttctacatca cgtagtaatt
//
LOCUS       DAFLWQ010000023        35882 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.024, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000023 DAFLWQ010000000
VERSION     DAFLWQ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35882
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.024"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..1152
                     /locus_tag="L1V16_001107"
     CDS             <1..1152
                     /locus_tag="L1V16_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HBN1275462.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSA
                     EAPKEKVETSGSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKED
                     IENFLAGGPSSAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPT
                     RKAIAKAMVNSKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALT
                     ATVKKYPVLNASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEI
                     NEKAKLAHDGKLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIV
                     NAEGEIVVGRVMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            1160..2566
                     /gene="lpdA"
                     /locus_tag="L1V16_001108"
     CDS             1160..2566
                     /gene="lpdA"
                     /locus_tag="L1V16_001108"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBN1275463.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            2728..3003
                     /locus_tag="L1V16_001109"
     CDS             2728..3003
                     /locus_tag="L1V16_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HBN1275464.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            3009..3776
                     /locus_tag="L1V16_001110"
     CDS             3009..3776
                     /locus_tag="L1V16_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HBN1275465.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            3944..5773
                     /gene="typA"
                     /locus_tag="L1V16_001111"
     CDS             3944..5773
                     /gene="typA"
                     /locus_tag="L1V16_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBN1275466.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            6034..7806
                     /gene="recQ"
                     /locus_tag="L1V16_001112"
     CDS             6034..7806
                     /gene="recQ"
                     /locus_tag="L1V16_001112"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBN1275467.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            7920..8222
                     /locus_tag="L1V16_001113"
     CDS             7920..8222
                     /locus_tag="L1V16_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HBN1275468.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            8225..9388
                     /locus_tag="L1V16_001114"
     CDS             8225..9388
                     /locus_tag="L1V16_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBN1275469.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            9414..12842
                     /locus_tag="L1V16_001115"
     CDS             9414..12842
                     /locus_tag="L1V16_001115"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBN1275470.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            12863..13987
                     /locus_tag="L1V16_001116"
     CDS             12863..13987
                     /locus_tag="L1V16_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275471.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            13977..14414
                     /locus_tag="L1V16_001117"
     CDS             13977..14414
                     /locus_tag="L1V16_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBN1275472.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            14398..14736
                     /locus_tag="L1V16_001118"
     CDS             14398..14736
                     /locus_tag="L1V16_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HBN1275473.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            14855..15415
                     /gene="rsmD"
                     /locus_tag="L1V16_001119"
     CDS             14855..15415
                     /gene="rsmD"
                     /locus_tag="L1V16_001119"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBN1275474.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            15412..15903
                     /gene="coaD"
                     /locus_tag="L1V16_001120"
     CDS             15412..15903
                     /gene="coaD"
                     /locus_tag="L1V16_001120"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBN1275475.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            15893..16936
                     /locus_tag="L1V16_001121"
     CDS             15893..16936
                     /locus_tag="L1V16_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HBN1275476.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            17095..17823
                     /locus_tag="L1V16_001122"
     CDS             17095..17823
                     /locus_tag="L1V16_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBN1275477.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            17939..18184
                     /locus_tag="L1V16_001123"
     CDS             17939..18184
                     /locus_tag="L1V16_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBN1275478.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            18181..18399
                     /locus_tag="L1V16_001124"
     CDS             18181..18399
                     /locus_tag="L1V16_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBN1275479.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            18535..19074
                     /locus_tag="L1V16_001125"
     CDS             18535..19074
                     /locus_tag="L1V16_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HBN1275480.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            19067..21340
                     /locus_tag="L1V16_001126"
     CDS             19067..21340
                     /locus_tag="L1V16_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HBN1275481.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            21378..22424
                     /gene="holA"
                     /locus_tag="L1V16_001127"
     CDS             21378..22424
                     /gene="holA"
                     /locus_tag="L1V16_001127"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBN1275482.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(22513..22767)
                     /locus_tag="L1V16_001128"
     CDS             complement(22513..22767)
                     /locus_tag="L1V16_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBN1275483.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(23167..23436)
                     /locus_tag="L1V16_001129"
     CDS             complement(23167..23436)
                     /locus_tag="L1V16_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275484.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(23906..24361)
                     /locus_tag="L1V16_001130"
     CDS             complement(23906..24361)
                     /locus_tag="L1V16_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBN1275485.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(24499..26427)
                     /locus_tag="L1V16_001131"
     CDS             complement(24499..26427)
                     /locus_tag="L1V16_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBN1275486.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(26624..27457)
                     /locus_tag="L1V16_001132"
     CDS             complement(26624..27457)
                     /locus_tag="L1V16_001132"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBN1275487.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(27649..28353)
                     /locus_tag="L1V16_001133"
     CDS             complement(27649..28353)
                     /locus_tag="L1V16_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBN1275488.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(28376..29002)
                     /locus_tag="L1V16_001134"
     CDS             complement(28376..29002)
                     /locus_tag="L1V16_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBN1275489.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            29328..31703
                     /locus_tag="L1V16_001135"
     CDS             29328..31703
                     /locus_tag="L1V16_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBN1275490.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(31727..32218)
                     /locus_tag="L1V16_001136"
     CDS             complement(31727..32218)
                     /locus_tag="L1V16_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HBN1275491.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            32405..33325
                     /locus_tag="L1V16_001137"
     CDS             32405..33325
                     /locus_tag="L1V16_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1275492.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            33479..33823
                     /locus_tag="L1V16_001138"
     CDS             33479..33823
                     /locus_tag="L1V16_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HBN1275493.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(34013..34513)
                     /locus_tag="L1V16_001139"
     CDS             complement(34013..34513)
                     /locus_tag="L1V16_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1275494.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            35041..35124
                     /locus_tag="L1V16_001140"
     tRNA            35041..35124
                     /locus_tag="L1V16_001140"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35075..35077,aa:Leu,seq:cag)
     gene            complement(35448..>35882)
                     /locus_tag="L1V16_001141"
     CDS             complement(35448..>35882)
                     /locus_tag="L1V16_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HBN1275495.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        11868 a         6262 c         7405 g        10347 t
ORIGIN      
        1 ccgtcacctg tcacagggac agttaaaaac gtgattgttc cagaaggcac tgtagcaaat
       61 gttggggatg tattagtaga aatcgatgct cctggacaca atagtgcacc gtcaactagt
      121 gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat caggttcagc aagtgtcgtt
      181 gaagctgccg atccaaataa acgtgtattg gctatgccat ctgttcgtca atttgcccgt
      241 gaaaaagatg tagatatctc acaagtaact gcaactggaa aaggtggcag agtaacaaaa
      301 gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg caccagcgaa atcagaagcg
      361 ccagaagcgg cagcaccgaa agaagcagct cctgcagcag aaagcaaacc agctgcacca
      421 gcaaaaccat tcaagtccaa cttaggagac ttggaagaac gtgtagcaat gacgccaaca
      481 cgtaaagcta tcgctaaagc aatggtcaac agtaagcata cagctccaca cgtgacattg
      541 catgatgaag tagaagtgtc taaactatgg gataatcgga aacgatttaa agaagttgct
      601 gctgcaaatg gtacgaaact tactttcttg ccatatgtcg tgaaagcttt aacagcgact
      661 gttaagaaat acccagtatt gaatgcatct atcgacgatg caaaccaaga aatcgtttat
      721 aaacattact acaatatcgg tattgcaact gatacggatc acggactata tgtaccaaat
      781 gtgaaagatg cagaccgcaa aggaatgttt gctattgcag acgaaatcaa tgagaaagca
      841 aaattagctc atgacggcaa actatctgca gaagatatgc gcaatggaac aattacgatc
      901 agcaatatcg gatctgtagg tggcggttgg tttacaccag tcatcaacta tccagaagta
      961 gctattttag gtgtaggaac gattgcacaa caaccaatcg taaatgctga aggcgaaatc
     1021 gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc accgtatcgt agatggagca
     1081 actgcgcaac aagcaatgaa taatatcaaa cgtcttttag ctgatccaga gctattaatg
     1141 atggaaggat gataaacaaa tggtagttgg agattttgct gtagaattag atacagttgt
     1201 aattggtgcg ggacctggtg gctatgtagc tgccatccgc gctgctgaaa tgggacaaaa
     1261 agtagcaatc attgaaagag agtatattgg cggtgtttgt ttgaatgtcg gctgtattcc
     1321 ttcaaaagca ctgatagctg caggacacca ttatcaagag tcactagatt ctgaaatgtt
     1381 tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa acacaagaat ggaaagaaaa
     1441 caaagttgtc catacgttga cttctggtgt tggtttccta ttaaaaaaac ataaggttga
     1501 aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca ctacgcgtca ttcatccaga
     1561 ttcagctcaa acttattcgt tcaataacgc aatcatcgca acaggttccc gtccaatcga
     1621 gattccagga tttaaattcg gaggacgtgt gttagattct actggcggat tagcattgaa
     1681 agaagtacct aagaaatttg tgatcatcgg tggcggtgtg attggtgccg aattgggcgg
     1741 agcgtacgca aacttaggag cagaagtaac gattcttgaa ggctcaccac aaattttacc
     1801 aacttacgaa aaagatctag taaaattagt agaagatgat ttcaagaaaa aaggcgtaac
     1861 agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac ggtgacagcg tgacagtgaa
     1921 atatgcagtg gacgggaaag aagaatccgt tactgctgat tatgtgatgg tcactgtagg
     1981 tcgtcgtccg aatacagatg atatgggctt agaacaagcg ggtgtcgaag taggagaacg
     2041 aggattgatc acggtggata aacaaggacg tacgaacgta cctaacatct atgccatcgg
     2101 tgatatcgtt ccaggggcgg cattagcaca caaagccagt tatgaagcaa aaatcgctgc
     2161 tgaagcaatc tctggcaaaa aagtagctgt agattataaa gcaatgccgg cagtagcctt
     2221 cactgatcct gaattggctt ctgtaggtat gacgatcaaa gaagcaaaag atgctggtat
     2281 cgaagcaaaa gcatataaat tcccattttc agggaacggt cgggcattat cgcttggtaa
     2341 aacagaagga ttcatccgtc tagttacgac gatcgaagat aacgtgctta ttggcgcgca
     2401 aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta gctttagcaa tcgaatcagg
     2461 aatgaatgct gaagatatcg ccttgacgat tcatcctcat ccatctcttg gcgaaatcgt
     2521 catggatgct tcggaattag cattaggttt accaatccat atttgatttg aataatacag
     2581 gcgaaacgca actgaaaaat cagttgcgtt ttgtttttta gaattatcaa taatattatt
     2641 atgtaaactt aaaaatatga caacttcttg gtttattacc acttcctatg ctacactgaa
     2701 gaggaatatg aaataggaga gttgaagatg caagaatatc agtatccact tgatttagat
     2761 tggacaacag acgaaatggt cattgtaatg aagatgtggg aagatctgga acgtgcgaat
     2821 gaaaaaggga taaacaatga agcttttttg aagacttatc agcagtttaa aactgttgtc
     2881 aaatccattg gtgaggaaaa acgattggga cgggaatttg aaaaagcttc cggttattct
     2941 ttatatcgta cagtgcagca agcaaaaaaa aatccaaaca aaactttgag aatgaacggg
     3001 tgagataaat ggaacagatg attgatcata tcaagtcctg gcttgaagaa gctggtgaga
     3061 aaatcaaatc ttctcaacaa acattaacaa tctcgcaaaa atcaaatcga acggatctag
     3121 taacaaatgt cgatcgaaac atccagaatt ttctaatcga aaaaatccat tcctttgatc
     3181 cagaggcgaa aatattggca gaagaagaag ggtgtaatca attatcggat ctcgatggaa
     3241 gagtctttat catcgatcct attgatggca ccttgaattt tgtgattgaa ggggaaaatt
     3301 tttgtattat gctcgctgtt tatgaatccg gcgttggaaa gcttggtttc atttatgacg
     3361 tgatgagaaa tgaacttttt tggggtggaa aaggaatagg cgtgtataaa aatgatgagc
     3421 cattgcctag accagcaaat aaatccttat cggaaggctt acttggtgtg aatagttatc
     3481 ttttcggtca taataaatat ggaatccgag aaattgcgga aagcagcatg gggacacgta
     3541 tgtacggatg cgctggtctt gaactagtgg caatcttgaa aggaaaccac attgcttata
     3601 tttcaaacct tagcccttgg gattatgcag cgggaaatgt cttattggaa gagtttggta
     3661 tggtaacaag cggtcttttt ggtactcctt tgacatttga aaaaagggaa tactatttag
     3721 cagggacttc ttgtgcatat gcagaaatcg cagacctttt gaaaaaagaa ggctgaaaaa
     3781 aaggtagaaa tcattcacaa aaatgataaa aacgagcaaa agattaattt tctcgaaaaa
     3841 atgaaaacat tttactatat ttcatgaaaa aagtctgcta taattagcag tcgagtaaaa
     3901 tttgccctgt cataaagaac caataaaaaa ggagttagtt acattgaatt atagaaacga
     3961 tatccgtaac gtcgcaatta ttgcccacgt tgaccacgga aaaacaacat tagttgatga
     4021 actattaaaa caatcagata cattagacgc acatacgcaa ttgcaagaac gtgcgatgga
     4081 ctcaaatgcg ctagaaaaag aacgtggtat cacgatttta gccaaaaaca cagctgtaga
     4141 ctataaaggt attcgcgtaa acatcatgga tactccagga cacgcggact tcggtggcga
     4201 agtagaacgg atcatgaaaa tggttgacgg cgttgtgttg gtcgtagatg cgtatgaagg
     4261 aacaatgcct caaacacgtt ttgtattgaa aaaagcactg gaacaacata tcacaccaat
     4321 cgttgtcgta aacaagattg acaaaccttc tgctcgtcct gagcatgtcg tagatgaagt
     4381 tcttgaacta ttcatcgaat taggagcaga tgatgatcag ttagactttc ctgtgattta
     4441 tgcatctgca ctaaatggta cgtcaagctt gtcagatgat ccagcagatc aagaaccaac
     4501 catggcacct atttttgata caattattga aaaaatccct gctcctgtcg ataacagcga
     4561 cgaaccatta caattccaag tttcattact tgactacaac gattatgtag gtcgtatcgg
     4621 aatcggacgt gtatttagag gaacaatcaa agtaggagac caagtagcat taattaaatt
     4681 agacggaaca gttaagaaat tccgtgtaac gaaattattt ggtttctttg gactaaaacg
     4741 tctagagatt caagaagcaa aagctggaga cttgattgct gtctcaggta tggaagatat
     4801 ctttgtcggt gaaacagtta ctcctgtgga tcatcaagat gcgttaccta tccttcacat
     4861 tgacgaacca acattgcaaa tgactttctt agttaataat tcaccatttg ccggtcgaga
     4921 aggtaaattc gtaaccgctc gtaagattga agaacgtttg atggcagaac ttcaaacaga
     4981 tgtatcctta cgagttgaac caacaaactc tccagatgca tggacagttt ctggtcgtgg
     5041 agaattgcat ttgtctatct tgattgaaaa catgcgccgt gagggatacg aattgcaagt
     5101 atctcgtcca gaagttattg aaaaagaaat cgacggtgta aaatgcgaac cgtttgaacg
     5161 cgtgcaaatc gatacaccag aagaatatat gggtagtgtt atcgagtcct tgagcttacg
     5221 taaaggtgaa atgcaagata tggtccatac aggaaacgga caaatccgtt tgacattctt
     5281 aacacctgcc cgcggtttga ttggttattc aactgaattc ctttcaatga cacgtggtta
     5341 cggaatcatg aaccatactt ttgaccaata tctgccaatg cttcctggtc aaattggcgg
     5401 acgtcaccaa ggggcgcttg tttcgatcga tacaggaaaa gcaacgactt attctatcat
     5461 gagtatcgaa gaacgcggta cagtcttcgt agaaccaggt acagaagtat atgaaggaat
     5521 gattatcggg gaaaacagcc gtgataatga tttgactgtc aacatcacga aagcaaaaca
     5581 aatgacaaac gtacggtctg ctactaaaga ccaaacatct gtcatcaaaa aaccaaaaca
     5641 attgacgttg gaagaatctt tggaattctt gaatgatgat gaatattgcg aagtaacacc
     5701 agaaagcatt cgcttgagaa aacaaatttt agagaaaaat gctcgtgaaa aagcatctaa
     5761 aaagaaaaaa taatctgtaa aaggatgaag agagaaacca gcttgttata aaaaatagct
     5821 ggtttctttt tttgtccaac tcttttctgt ggagaagtca tctttgtcaa tggacataaa
     5881 ttcagaaaat acgccgaaag acgtttaaaa gacttttaaa aaacttattt ctagagagtt
     5941 tttgtttcat aataagataa tgtttcacga aaggagatca acttgtcctt cgaagaaaat
     6001 cgaagtaaaa tggcaagaga aaggagcggg aagatgaacg acttattaaa acaatacttt
     6061 ggctatgatg agtttagacc tggtcaaaaa gaaattatcc agaaagtcat tgatcaggaa
     6121 aatgtattag gaatcatgcc taccggaagt gggaaatcaa tctgttacca gcttccagct
     6181 ttactattag atgggcttac tgtggttgtg tcccctttaa tctctttgat gaaggatcag
     6241 gtggacgcgg cgaatcaatt aggtataccc gccactttta tcaatagctc gttagatggt
     6301 tacgaaacag ctagacgctt ccaagaaatc gatagacagc agtaccgttt actttatatc
     6361 gctcctgaac gttttatcat gccggatttt atccaagcaa tgaagcgatg gaacgtccgt
     6421 atgatcgcta ttgacgaggc acattgtatc tctcagtggg ggcatgattt ccgcccaagt
     6481 tatttacaga tggcgaacca gctagatcaa ctgccaaatc gtcctgtaat tgttgctttg
     6541 acagctacag cgactgtgca agtagctgct gacataaaaa gacttttaaa aattccagaa
     6601 aacaaccata ttcagactgg ttttgaacga gaaaatctac gatttcaagt aattaaagat
     6661 caaaaaaaag aacaatatct aatcgaatat ttaaagatca acaaaaatca atctggtatc
     6721 atttatgcag caacgagaaa agaagtagac cgtctctatc atttgcttaa aaaattcgat
     6781 ttttccgtgg gtagatatca tggtggtcta aatgagaatg agcgaacaga aatgcaagaa
     6841 gcctttttat acgatcgctt gcagctgatt gtagcgacaa atgcatttgg tatgggtata
     6901 aataaaagca atgtccgttt tgttatccat tatcaaattc ctggctctct agaagcatac
     6961 tatcaggaag ctggtcgggc gggaagagat ggtctttcca gtgaagccat cctgcttttc
     7021 tctcctcaag atatccaagt ccaaaagttt tttatccagc agtcccaaag agaagaaggg
     7081 caaaagcaaa aagaatatga aaaattaaaa gcgatgacag aatacgtgta tattgagtcc
     7141 tgtcttcagc aatacatcct aaactatttt ggcgagacaa gcagtccgtg caaccgttgt
     7201 ggtaactgtt tagatgacag agaaatagta gaagtaacga cagaagcaca gatggttctt
     7261 tcttgcttaa aacgtatggg tgagaactat ggtaaacaaa tgctgatgaa agtcttagca
     7321 ggatcgaaag aacaaaagct gcaagcttta ggttttggac atttatctac ctatggactg
     7381 atgaaaaacc aatcgcaaaa agaaacgatg cagttaattg aatatttgat atcgaatggc
     7441 tatcttctga ccatcaatgg tgagtatcct gttttgaaag taacagaaag agggatacaa
     7501 gtattgaaag gacaagaatc tgtttatcga aaggaaccca agaaagtcca gcagctatcg
     7561 gatgaagaaa ccgatacact atttgaagtg ctgcgggaac tgcgaacgga tctagcatca
     7621 gaagcaggcg ttcccccgta tgtcgtattt tcagattcca cattgaaaga aatgagccga
     7681 atacgtccat caagcagatt ggagatgctt cagataaaag gagttggcca aagcaagctt
     7741 gataaatatg gcgaagcctt tttatctcgg ataaaaaatg cggactctaa cgttctggat
     7801 aagtagaaag aacgaatacg taaaaatgaa taaaaacaac tggttaaatc tgtttttttt
     7861 gctccttatg aaaatcaaat atgttataat taaggaatta gaatgggagg taagcacaga
     7921 tggattcttt gtcgaaaaaa cttgcgatcc aagtattaaa tgatgaagca gaacggatca
     7981 aacgattaat ccgaaatcaa aacaacagtc tctgtatctc acaatgcaaa gccttcgaag
     8041 aagtggtaga tacacagatg tacggctttt cccggcaagt cggttttgct gtccgtatag
     8101 gagtaatcgg aaagaacgag ggccagctga tgttaagtga gctagaacga gaattgaatc
     8161 agttatatag tgaggtttac caagaaattt atgataaaaa agaagttggc aaggaggaat
     8221 agacttgcct aagaaagtga aaaaaaggca tctattagac tatagcatct tgattcccta
     8281 tttaatttta tgtgtattgg gattgatcat ggtatatagt tctacgtcgt atctattatt
     8341 agaaaacgga caaaatccgt ccgcatcagt cattaaccag agtatttttt gggtgcttag
     8401 cttgattgct atcgcactac tttataaaat gaaaacagat gttttgaaaa accagcgttt
     8461 gatcatggca gccatcgcag ttttgacgat tttgctgctg attgttgtgt tttttggtaa
     8521 ggagatcaat ggggcgaaag gttggctgca aattgcagga ttctcgatcc aacctgccga
     8581 atacctaaaa atcatttcta tctggtacct gtctctgact ttatctaaaa gacaaaacag
     8641 tgtacaaaaa gattttcttg ggactgtgaa acgtccactt gcaatggtta tcggacttac
     8701 tgcattagtc gctattcttc ccgattttgg taatgcggca gttatctttt tgattatttt
     8761 ggttctgctt ttagccagcg gagtcaatta tgtgtatact ttgattgtag gagtaggagg
     8821 cttttgtcta agtactttta cgatctggct gatcaatatc acaaacggaa agatcttacc
     8881 cggacgttta cagtatatct ataatcgatt tgctatttac caaaatcctt tctcagacga
     8941 attaaataaa gggcatcaac tagtcaacgg ctactatgcc atgttcaacg gaggactatt
     9001 tggcagggga ttaggtaaca gtatccagaa aaaaggattt ttacaagaag cacaaaccga
     9061 ttttatttat gcaatcgtag tggaagaact gggagtgatt atggggattt tgatattagc
     9121 gttgctattc tttatgattg tgcgcattgt ccttgtaggt atccgttcaa aagatccgtt
     9181 caattcgctt ttgtgcattg ggatcggcgc aatgtttttg atccaagtat ttgtcaatct
     9241 tggaggaatt actggcgtta ttcctttgac agggatcacg ttcccatttt taagtcaagg
     9301 aggctccagt ttgctgatgc tttcgatttg tgtcggcttt gtcctcaaca tcagtgcgga
     9361 tgaaaaacgc aagagcttag gtttataata aaaaaagatg taggagtggt tcgatgaaaa
     9421 aagttttagt tgctaacagg ggtgaaatcg ctgtacgtgt atttcgtgct tgtacagaat
     9481 taggaattaa aactgttgga atctatgcag aagaagatga atattccgta caccgtttca
     9541 aagcggatga agcatattta gtaggacaag gaaaaaaacc gattgatgcg tatctagata
     9601 ttgaagggat catttctatc gcgaaagaat gcggagctga cgctattcat ccgggttacg
     9661 gtcttttgtc ggaaaacttg aattttgcgc aacggtgcga agaagaaggc atcatttttg
     9721 ttggacccaa actgcatcat ttagatattt ttggagataa aatcaaagca aaagctgcag
     9781 ctatcgaagc ggggattgct tcgattccag gcacagatgg accaatcgct tctatagacg
     9841 atgccttgga gtttgcgaaa caatacggtt atccgattat gatcaaggca gctctaggcg
     9901 gcggcggacg cggcatgcgt gtagctcacg atgaaaagag tgcaagagag ggctacgaac
     9961 gtgcgaaaag cgaagcaaaa gcagcctttg gtagtgatga agtgtatgtt gaaaaataca
    10021 tcgctaatcc taagcatatc gaagtacaga ttctcgggga tacgcatgga aacgtcatcc
    10081 atctttttga aagagattgt tctgttcagc gccgtcacca aaaagtagta gaagtagcgc
    10141 cttgtgtctc tatgaatgaa cagcaacgtc aaaaaatctg ccaggcagct gtccaattga
    10201 tgaaatatgt cgggtatgtc aacgcaggta cagtagaatt tcttgttgaa ggagatgatt
    10261 tttactttat cgaagtcaac cctcgcgtcc aagtggaaca tacgatcaca gaaatgatta
    10321 cagatattga tatcgtaaca acgcaactgt tgattgctca aggtttggat ctgcataaag
    10381 aaatcggatt gcctcagcaa gaaggaatta aattaaatgg ttcagccatt caatgccgaa
    10441 tcactacaga agacccgttg aataactttt taccagacac agggaaaatc gatacgtatc
    10501 gttcacctgg tggttttggc gtacgtctgg atgtcggaaa tgcttacgcg ggctatgtag
    10561 tgacaccgta ttttgattca ttgctagtaa aagtatgtac gcatggtgct acctttgaaa
    10621 cagccattca gaaaatggaa cgttgcttga aagaatttag aatccgtgga gtgaaaacaa
    10681 acattccatt tatgctcaat gtcatcacac atcctgaatt ccaatcagga aatgcaaaaa
    10741 caaccttcat tgatagtaca gcaacattat ttgaatttcc tcgactacga gaccgcggaa
    10801 acaaaacgat gaaatatatc ggtgaaatta ctgtgaatgg ttttccaggt atcgaaagtg
    10861 gcgaaaaacc attttatgaa gaaccacgta tgcctaaaga tctaatcaca agaactgatt
    10921 acgtaacggc taagaatgta ttagatgcga agggtgccga tgctttggtc gaatggatca
    10981 aaggacagga aaatttgttg ttgacggata cgacatttag agacgcccat caaagtctgc
    11041 tagcaactcg tgttcggaca aaggatttca agcagattgc acgtttgact ggagaaggtc
    11101 ttcctgaact cttttcaagt gagatgtggg ggggagcaac atttgatgtg gcttaccgct
    11161 ttttgaatga agatccttgg caacggttga gaaaaattcg ttctttaatg cctaatacgt
    11221 tgctgcaaat gcttttcaga ggttcaaatg ccgttgggta ttctaattat cctgacaatg
    11281 tattggtgga atttgtcaaa gaagcagcag cgcaaggaat cgatgtattt cgaatctttg
    11341 atagtttgaa ctggactcca caaatggaaa aaagtatcca agctgtacgg gatactggta
    11401 aaatcgcaga ggcagctatt tgctatactg gcgatatcaa cgatccaagt cgggcaaaat
    11461 acaatgttca gtattataaa gacatggcaa aggaactaga acaactgggt gcgcatatca
    11521 ttgcaatcaa agatatggct gggctgctta aaccgcaggc agcttatcgt ttgattagtg
    11581 aattgaaaga aacgacagat ctgccaatcc atctgcatac tcatgatacc agcgggaatg
    11641 gaatcatcac ttattctgct gcttcaaaag caggagtaga catcgttgac gtggcaatga
    11701 gtgcaatgag tgggaatact agtcagccta gcatgagcag cttgtattat gcactggtca
    11761 atggtccacg gctgccagaa atcacgattg aaaatgcaca gaaattaaac cattattggg
    11821 aagatgtgcg catgtattac aaaccgtttg aaaacggctt gaatgctcct gaaacagaag
    11881 tatatatgca tgaaatgcca ggaggacagt attcgaatct acagcaacag gcaaaagctg
    11941 tcggattagg tcatcgctgg gatgaaatca aacaaatgta tcatactgtc aacttgatgt
    12001 ttggcgatat cgttaaagta actccatcat ctaaagtagt tggagatatg gcactattta
    12061 tggtccaaaa tgatcttaca gaagaagata tttatgaaaa aggcgaaaca ctaagtttcc
    12121 ctgaatctgt tgtgactttc ttccaaggag aactagggca acccgttggc ggatttccta
    12181 aaaaattgca aaagattatt cttaaaggca gacctgcatt gaatgaacgt ccaggtcttt
    12241 tggctgaatc agtcgacttc aacgaagtaa aaaaagaatt ggcagaaaaa attggctatg
    12301 aaccaaaaca agacgaagta ttaagctatt tgatgtatcc gcaagtcttt ttggactatc
    12361 aaaaagcata taatcaattt ggcgatgtta cattactgga cacaccaaca tttttccaag
    12421 gtatacgttt gggtgaaaca atcaatgtac aaatcgaacg cggaaaaacg cttatcattc
    12481 gtttagatga aatcggagaa cccgatatcg aagggaatcg cgtactgttc ttcaatttga
    12541 atggacaaag acgtgaaatc actatcaaag ataattcgat catcagtacg gtccaaaccc
    12601 gattgaaagc tgaaccgaca aaccgagaac aaattggagc aacgatgtct ggttctgttt
    12661 tggatgtatt agtgaaaaaa ggcgataacg ttaaaaaagg tgatacgttg atgattactg
    12721 aagcgatgaa aatggaaacg gccatcgaag cacgttttga cggagaagtc gcacatgtat
    12781 atgtgtcttc aggagacact atttcgtctg gtgacctttt gattgaagtg actgagaaat
    12841 aataagcgaa aggtggggaa acatgaaaag actgggtttg ttttggctga ttctgctatt
    12901 agttattgtg gcattctaca tggaaccagt cttgtttccg ccaaaacttg aagtgaagga
    12961 aaactctgat caacaaatat caaaccaaat gacaacgtgg aaataccagg agcttaaagc
    13021 aactggtttt tctacttata tcggaaaacc gatcgatcag ctggaaaagg attttggcca
    13081 agcctatgat cgattaacta gcggatttgg ttttgaaaca agatattatg aaaataaagc
    13141 tagtcatctc acatttgaag cgaacatcca agacagcaga gtcacaactg ttaaagtact
    13201 gcaaacaggg cctgctgata tcgcgccgtt ttatttaggg atgacgatgc aagatcttac
    13261 gaaaatcact actatctata ctaatttcac ttttgagtac catgatacag aagttggaat
    13321 cgaactaatg gaagaggata tgaattatcg tccgctaatt gcttttgata acgacacttt
    13381 tgctatttta ttttttgatc aaacaacaaa cggcctattt tcagttgtgt atttagataa
    13441 agatagtctt ttgaaactat tgccatatca agtgtttggt gaaggccttc cacattatca
    13501 agcagataaa tcggctgatt gggaatcaat caatcgcgtt aaagaacgaa aaagtacgac
    13561 tttattaaat atgcttagaa gagaagacga acttcccata tacaatcaaa cacttgcctt
    13621 tcaaaaccac agtcagctgc tactacatga ttttttgaca aggcctgagg aaatattgtc
    13681 agaggaacgt atggctgatt ggcaaaaatc gctaggcagt gctcaaacga cagtgaaatt
    13741 ctcactgacg aatgatgaat tggagaagtt aatcagtaaa caaaaattag aaaatactag
    13801 tgggctattt attcatccgg cgattgacgc tactttttcg tttttatatt ggtacagcga
    13861 tccttacaac catgaccgtt tcatggaccc gggaacggat tctgtaggca ttgctttttc
    13921 taaagaaaat atgttagtct tattgcaaga agaaaacgga gaaagtagtg atagcagtga
    13981 tcgttaacga agagctgttt caactggagg atcaatgcct ccaagtcgct gaaatgataa
    14041 aaaagagtaa aacgatggct tcttatcttg aacataaaca gtcaatggaa gaatctgcaa
    14101 aagtttgcca gttgaaagaa gcgttcttgt ctaagaaaga agcatttgaa aatgtagcgg
    14161 catatggtga gtatgcacct gattatcgtg aaaaaaaacg agctgttcga aaagcaaaaa
    14221 gacagcttga tatggatgag catgttgcag ctttccgata tagtgaaaca cagctgcaaa
    14281 gtctgttgga tcaaattgtc caagtacttg ccgaagaagt ttctaatgaa atcaaagtag
    14341 atgcaggtag cccgtttttt gaaacgaaaa aacactttgg atgcggaggt aattgtcatg
    14401 caattagaca atagtgaatt tgaaataaca aaacgacgcg ggctgatcgt atgggtctac
    14461 agcttaaaac aattaaagaa tctgaaaaag ttcggcttgt tgcattatgt ctcaagaaga
    14521 atgaaatatg tcgtgcttta cttaaatgaa gagacattgg aagaaacaga agaacgaatc
    14581 cgtaaattac attttgttcg aaacgtagaa cgttcttacc gaccggatat cgaaatgaat
    14641 tttgccgaaa aaataggaaa caaaacagta ttaaaagacg aaggtttcga aattgaagag
    14701 ctaaatacag aaatccgatt agctgaacat ctttaaaaat ctcttatgag cagtttttaa
    14761 ataaaaaata acttggataa cgatcgattt ttgatcattg tccaagtatt tttttggtat
    14821 actagtacca gtaccatttc taaggagtga gtagatgcgg ataatatcag gaaattatgg
    14881 cgggcgccgt ttaaaaagtt tagcaggggc gaacaccaga ccaactacag ataaagtaaa
    14941 agaatccata ttcaatatga ttggaccata ttttgatgga gagacagtat tggatctgtt
    15001 tgcaggaagc ggtggtttag ctatcgaagc agtatctaga ggctgcagtc atgcggtatg
    15061 cgtagacaaa aattaccaag cgctaaaaat catcaaagaa aacatcgaaa ttacgaaaga
    15121 accagagaaa tttaccacaa taaaacttga tgcggacaaa gcaatcgaac ggctagcagc
    15181 ggagaaacaa caattcgact acttgtttct tgatccgcca tatgcaaaac aaaaaataat
    15241 cgatcaaatc cataaaatgg aagaactggg acttttttct aaaaccgcag ttatcgtatg
    15301 cgaaacggat aaaacagtcg aattgccaga aactgtggct ggattccatc aaataagaaa
    15361 acagatttat ggcataacgg ccgtaactat ctatagaaaa gagggaaatc aatgaaacgt
    15421 gcattattcc caggaagttt tgatcctttt acaaaaggtc acttagatac ggtggaacgt
    15481 gcggctaaat tattcgatga ggtagtaatt ggtgttttta tcaatacttc aaagaaaagt
    15541 ttgtttcccc cagaagaaag aatgacattg atcacaaaag ctgtttctca tcttcctaat
    15601 gtaaaagtca tgcatcaaga aaatcaattg acggtagaaa cagcaaaaga gattggtgca
    15661 gatgcgttga tcagaggcat acgaagtatc aaagactttg aatatgaacg agagattgct
    15721 cagatgaatc atcatctata tgatgaattg gaaactgtct tcttattagc aaaaccagaa
    15781 tatagtcacg tgagttccag tattttaaaa gaagtactgc actttggcgg agatgtgagc
    15841 agctacttac cgccagtgat caacgaagct ttagctggaa agcgtgaatc aaatgaaagc
    15901 taaacaatgg ttgaaaacag tactgattat catatttgga atgttgatca ttggatttgt
    15961 agtagttccc ttgccgtatt atgtagaatc accgggagcc acgatcgatc tgaaagaact
    16021 aattacggtc aatgataagg aagataaagg ttctgggtct ttctctctta cctctgttgg
    16081 tatcaggcaa gctacaggtt tcttagcttt aaaagctaaa atgacccctt ttgaagaatt
    16141 gatcagtgaa gaagaattga ctggtggggc gacaaatgaa gaatataatc aaatgcaaca
    16201 gtattatatg gattcttccc aaaatgcagc aatcgaacaa gcgttaaaac ttgcagacaa
    16261 gccttataaa atggaattca aaggcgtata tgtcatgagt gtagagaaaa catcgaattt
    16321 ctttggcaag ctttcagttg gagatacagt aacaaaagta gacgggaaaa gctttcaaag
    16381 tacagaagca tttatggatt atgtaaaaag ccaaaaagtt ggacaaacaa tcgaaatcag
    16441 ttatttgcat aatggtgaag aaaaaacagc ttctggtgat ctgatcgagt taccaacaga
    16501 taaaaaggca ggaataggta tcacgcttac tgaccatacc gagatcgaat cagatacaga
    16561 tgttcgtatt aattctggct ctatcggtgg gccatcagcg ggattgatgt tcactttaga
    16621 aatctatgaa caagtcactg gtaaaaactt gcgacatggt aagcaaattg caggaactgg
    16681 aacgatcaac agtgaaggag aagttggccg aatcggagga atcgataaaa aagtggcaag
    16741 tgcggataaa gctggcgtag agattttctt tgcaccagat gatacgattt cagacgatgt
    16801 taagaaagaa tatcctgaaa taaaaaccaa ctacgaagaa gcaaaagctg ccgctaaaaa
    16861 attgaattcc tcaatgaaaa tcgtaccagt aaaaacagta caagaagcgc ttgactatct
    16921 agagaaaatg aaatgaaact aaataattaa agaggggttg tgacacgagt tctgtcacaa
    16981 cccctctttt tcgtcaaaaa tcttcacgat aaaaataaaa acaaaagaaa aaattgacgt
    17041 aattagatgt tgaagggacg attttgccag agctcactgt ttcttcaatt ttaaatgaaa
    17101 ggagtaatga atgattttta ctggtcattc tttgaaaaaa gaacaatgat agaaaaaatc
    17161 agcaagaaaa tactagcttc acccaaattg atcatttgga tgtctatgat agttcttatc
    17221 ttttgtatcg caagtggttt tttattatca aatttgctat tttatagaga aacagaagag
    17281 actgctgcaa aagaaatact ttcttcgttt agttccagtg gagaagatcc atcagctgaa
    17341 ggaaacgatg tagaagagga tgctcgtcca aaggtcatgt acaccgatat caaaggaagt
    17401 gtgaaggagc ctggtatcta ttccttttct tcagaagaac gggtctatga tgtactaaag
    17461 cgtgcaggtg gattattaga agaagcggat agcgatcgaa tcaacttttc tgcgaagata
    17521 gaagatcagc aagtcctata tatccctgct gtaggtgaag agctgccaga acatcttgat
    17581 cagttggcat cctcggaagg aaaacagcct acagcagatt ccgagcctcc caaaataaat
    17641 atcaatacag ccactccatc agaacttcag cagattcctg ggatcggatc agtcaaagcg
    17701 caagaaatca ttcgatttag agaagaaaac ggatccttcc agaaagtgga agacctgcag
    17761 gagatttctg gtatcggtga aaagacagtt gaaaaactaa aaaacttcgt tacaattaaa
    17821 tagaatgatt caaaatcgac tggcacgagc aataaatgga cgctaatgga tactaagaat
    17881 aatccaattc taagagcttg gcaggacgag gaggtagtat ttttggatag gaaatagctt
    17941 gattgttcgc aaagaaacat taaaaaaacc aatgctgaat gtctatctcc aaaataaaat
    18001 atctgggatt catattatga atacggctgt cagcggcaat aacagtcaag ctctacgaga
    18061 acgctttgcc aaagatgtac ttagctatac agcagataaa gtatttattc tcattgggac
    18121 gaatgatcta gcagagcata aacaactttc taaagaaacg taccaaaaaa tctgcagtgg
    18181 atgatagttc agctgaaaaa agactatagt tctgatcatg ctttctttat cacgccacca
    18241 gcagtcgatg agacaaaaca aaaatatcgg aataacaagt tgatcaaaga atatatctct
    18301 gttctcacag aagtagcaaa acgccatgat tgtgaagtat cgatttttat acggaatttc
    18361 ttgaacaaat ggattcgaag aatttttata atgggctaat ggatgacgga cttcatttcg
    18421 gcagtgaagg gtaggatctt ttgtcagaca ggatgattcg ttatatttaa agaatatttt
    18481 gtttaagcaa tgagtacttt ttaatcaact tgaaaaaacg gaggaatata aaacatgtta
    18541 gaaaaatctt caaaagcatg cgatacgaat aaagaaaaag ttactgataa gtcacataat
    18601 gaacgcattc cttgggacca gtactttatg gctcaggcag tactgttatc tttacgtagt
    18661 acgtgtacac gtttagaagt aggagcgaca ctcgttcgag aaaaaaggat cattgctggc
    18721 ggctataatg gagcagtcag tggagatgtc cactgcatag atgaagggtg ttacgtcgtg
    18781 gatggacact gcttgcgaac gatccatgca gagatgaatg cactcctaca gtgtgcaaaa
    18841 cttggtatcc cgacggaagg ttcagaaatc tatgtcacac attttccatg tttggcctgt
    18901 acaaaggctt tgttgcaagc tggtgtgaaa gggatcaatt atctccatga ctatcgaaat
    18961 gatccttatg cccaagcgtt gatcgaacaa ttaggtgtat ctgtacacca agttgcttta
    19021 gactcacagc atttttcaaa acttcaaaat gaattaacag gaaaacatgt ctagcgtttt
    19081 agaaaggcat gttcgaaatc ggttgatttt tccggcaatt acgtcgatga ttatctgttt
    19141 gttgtattac actgacaatt ggggttatcg tttgcttctt gccggaattt ttttatggtt
    19201 ttcgctaaaa gaaggacgtt ttatcgcgta cttgtgtatt ttgtgtagca taacggtatc
    19261 catttcttat aggctacaag agtattcatt tttagaggaa aaaacaacat ctgcgcaaat
    19321 tactgtattt acagatacga ttcgtgcaaa tggtaatttt ttgacaatgg aaggaaggtt
    19381 atcagagaat aaacaaaagc tccagctttc ttatcaagta aacacagaag cagaattgaa
    19441 aacatggctt aacttccgag gaaagggaat agaattgact gctgaaggcg agttcatctc
    19501 tccagcaaaa aagcggaatc tttataattt tgaccaagaa gcttacttca ggaaccatag
    19561 aatttctgga cggttccaaa ttcaaaagat tgaacagatc accatgcaaa atcactggcg
    19621 aaactggctt cagagaaaaa gaggatcttt tatctccttt gtccaatctg aatttccgca
    19681 aaaaacaagt gtatatatta attctttatt atggggctat aaagatgcag gattcagaga
    19741 accagaagaa atttttaggg agagtggttt gctgcatctg ttcagtctat cgggtctaca
    19801 catccaattt tatttagggt ggctgtatta tttgtttcga cgtatcggat ggccactaca
    19861 cgtcagtatt attccgttga gtctactaac tatctgttat gtttctattg caggaagttc
    19921 tatttctgtt ttgcgtgcta gtttgctgtt tttattgcga ttgctagtca aattgctgaa
    19981 taagcattat tccaccatgg acttatttgc agttgtcttt tggcttcttt tactatttga
    20041 tcctcgattt ctttttcatg cgggtggaca gcttagtttt ttcatgagtt ttttgtttat
    20101 cctgatttct tttgatggag attggttgaa aaaaacggcc tctcacgtcc tgtttactat
    20161 gatcacgatg ccgttgattg tatggcattt ttatgagtgg cctattttag gtagtctttt
    20221 tacattactg attgcaccgg tattcaagtt tctttttctt cctggtgtgt tatttctcac
    20281 actcttcaat cgctggctgc cggaaacttt acttttgctg atagaagagg gattaatctt
    20341 atttgagcga ataatcgatt tttcttcagg gtcgtctctc attataggac gtttgcccct
    20401 tgtgctatct gggatgtata ttttcggatt actgatttgt atggataggt tgaaagaaca
    20461 acctgtgaaa cacttgtttt atgttggtct tttttctttt atttttttga ctttgccatt
    20521 tttacgcttt tcttcaacga tcgcttttat cgatgtcggt caaggagaca gtatcttttt
    20581 gcaaagtcct tttcgaaaag aaacgatttt gatcgatact ggaggtcagt tacactttga
    20641 aagagaaaag tgggcgcaag gtatgatacg tcctcctgct gaaagaaata tcgttccata
    20701 tctaaaaggt caggggataa gtgtaatcga taaactcatc ttgacacacg acgatacgga
    20761 tcatgtggga gaattaccca cgttatctca gcattttact atcaaaaaaa tttatatcgg
    20821 ttggggcgct ggacgaaatg agccattaca aaggcattta tctgaagctc aaaaaaatgg
    20881 tactgagatc attgaaatca aacatgggga caggatcagc ggttattatg atctttatgt
    20941 attgactcct tttgaaaagg gagagggaag aaatgaagat tcgattggtc tatggatgga
    21001 atataacaat aggcgctttt tatttttagg agatttgaat caagcaatgg aaaaacaatt
    21061 gcttttgatt tatcctaatc tgaaagccga tgtagtcaaa ttaggtcatc acggtagccg
    21121 tacgtcaagt aacacagatt ttctttccca tattgaagca aaacatggga ttatatcctg
    21181 cggcgtaaat aatcgttatg gtcacccgca cagcgaagta ttggagacac tagaagaaaa
    21241 tcagataaaa acatggcgaa cggatcaaca aggaatgatc acctatcgct ggcatccagt
    21301 ttttcatcct catgggctag tggaaacaat gatagactag taattctcat ctgctcatgg
    21361 taggataatt tttgaaagtg gtgagtaatt tgagtataca agcagagtta caaaaaatac
    21421 gtaaagaaaa acttgcatct tgttacttga ttttaggaac agaaaagttt ctccaagatc
    21481 aagttcggac agaaattgtc aaaaaaatcc aattagaggg cgaagatgac ttaaattttt
    21541 taagttttga catggaaaat gcaagtttag atgaggtagt agctgaagca gagacgttgc
    21601 cgtttttcgg agatcaacgg ttagtattcg tagagaatcc ttatttttta acaggtgaaa
    21661 aagtaaacaa tggaatcgaa caaaatactg atttattgac ggcttatttg aaagaaccat
    21721 tagaatcgac tgtattagta ttctttgcgc catatgaaaa gttggatgaa cggaaaaaag
    21781 taacgaaaca attgaaaaaa acagcaatta tcatcaatgt ccaacagttg aatgaaaaag
    21841 aagtacgtca atatctgatg aataccttag agaattcctc aatcaaaatg gaacgaagtg
    21901 caattgattt attcttgagg ttgaccgact tagatttatc caaaatgatg agagagttac
    21961 agaaattggt cctttatgga caaaatcaac agcaaatcac ggtaagagaa gtagaagaat
    22021 tagttcctaa aacgttagaa cataatattt ttgacatgac ccaatatatt ttaaaaggga
    22081 agacggaaca agctttgcgt ttatacgaag atttagttat gcaaggggaa gaaacaatca
    22141 aaattaatgc gattttgctt tctcaattac gtttattttt acagacaaaa tttcttgtaa
    22201 agattggtta tcagcaggca aatattgctg aaacattgaa aatccatcca tatcgtgtaa
    22261 aacttgccat gcaggaagta aaaaaattcg atgaacattt gctggtacag ttgtttgatc
    22321 aattagttga gatggattat caaatcaaaa cgggacaaat cgaaaaagaa ttaagttttc
    22381 aactattcgt tttgcgcaca gggcagttgt taagaaatcg ataagaagaa agacgagggc
    22441 aaagcatgcg ggaaggtcgt ttgtttttgt cctttttttg acaaataaaa aaatcggccg
    22501 aagccgattc ttttatttag cgattttttt gcttaaacga gatttgtcgc ggttagcttt
    22561 gtttttgtgg attagacctt ttgattcagc catatcaata gctttaacag cttctttata
    22621 taacgcatct acgttgtcag cacctgaagc tacagcatct tcaaattttt tgattgcagt
    22681 acgcatagcg cttgtttgag atgaattttt cacattagcg ttttcgcttg tacgaacacg
    22741 tttgattgca gattcaatgt ttggcattag tttcacctcc gataacttaa gttcttacgc
    22801 gtgttaccgc ataattcaac attcattatt atacctaaag gcagcgtgct ttgcaatatg
    22861 aacatgacaa gtttttttcc ttaacagtct tttattagga ttttttttca gtaaaaacgg
    22921 atagtacaag ctgaaaaaaa tcaaaaagac gctattgtgg gaggcaatag cgtcaaacca
    22981 aactagattt ttatttatct atttaaacaa agtttgaatg ggaatgtttg gtactaagtt
    23041 attatataac aaagagaacc gtttgcaaag ttttttttga aaagggatac gattccctgt
    23101 tgttctttgt ttttctatta agaaactgca gttattttat aaccagtatc ctttgatcag
    23161 taaaggctat tctggtgtac cgattatttt aatgtattca tcgatatttt ttatcaacat
    23221 tttttttatg accaactggt tccgacggtt ccatttgcca cttacttcca gcacatattt
    23281 atttaggggc aaacgtaaga tatattttgc caaatagcga tctttaagca ggccattgat
    23341 cacacggtcc tcaagctgca agttgatccc agtcagcatc attggctgtt cttgtaaaac
    23401 gtacgtatca attaaaagac cttcaaaagt ttccacaagc gtcttccttt cttttcaaag
    23461 taacctgaaa acaggcacta attcttccat tttgatattc gttgaagtgg atgcgatcat
    23521 tctttctttt gtccactgta atctagtata acaaaaaaga gcagaagagc caaaaagaaa
    23581 aaagagcatc gaattctata ggaagtctca ttggcacggc ctaaattatt acaaaacatt
    23641 gattaaaaaa agcccctgca tcgcaggagc atcccctata tcgttttaat aggtcaatca
    23701 aaaagcagta tcaaacacat tttgtatcaa atcaggaaat aatagataag ctaagcccag
    23761 aatcaaaagt accgctagaa gaaaccagcc gattgttcct atgaaatact ttaatttttc
    23821 gaacattgta tcacctcgtt gtcagtatat cacggatcag taaattgggg gtgttaagaa
    23881 tctcctaaaa tagacaaaat ttgttctatt ttcctaaagc aaatacttgt aagatacagt
    23941 aagtgatacc agaagcaatg accggtccgg cggcgattcc tcttaagaag acaacaccta
    24001 aaatcgtgcc gaaaacaagt gcaacagtga tttgtggatc agaagcaatc aatcctacac
    24061 ccttggaaga taagacagcc actagcccac cgcaaaaaac agctacccag ccaatagggg
    24121 atttaaaggc ttctaataga tcacgtagac cgatttctcc tgttgcgata gggattagaa
    24181 tagccgctgt gatgatcgtc accccaatat tgattccttt gccttgaagc caagggaaaa
    24241 aggaacggga ggctggtatg agcttcataa tcaaaacaaa agctgccgct atcatcagac
    24301 tttgattttt agctaaaatt gctacaagta aaataattcc taaaaaaagc caactttcca
    24361 tgaaatatat tcctcacttt cttcgaaaca atcataacat gtttttagaa agttacaaaa
    24421 gtaggaattc atccttcaag acctattcat aagctgtttt tttcataaaa taaacaaaat
    24481 cataaaaaaa cactttgctt atttgacaga agacagccgc gctttgtata gtggacaaga
    24541 cttacatttt tttgaagaat cagaaagatc aggtaaaggt cttagtaaac gcaagccatt
    24601 cagaataacc aatattgtgc ttccttcgtg tcctacaact ccaagaggta gatttaaaaa
    24661 ttgcaggaag ttagaagcaa tcaacaagag aataacaaga atcgaaaaaa taatattttg
    24721 tttgatgatc cgccgcattt ttaaagatag ccgatgactg tagacaaatt tatttaagtc
    24781 gcttttcatt aagacgatgt ctgcgatatc catagcggca tctgtccctt gccccatagc
    24841 gacacctaaa gaagcggctg ctaaagcagg cgcatcattg actccatcac caaccatcgc
    24901 atttacttgg taaagttcat tctctttttt gactagttgt gttttttctt ccggagtaca
    24961 gcttgcatag taatgttcaa tccctacttg ttcagcaatg gcctttgctg tgccagaatg
    25021 gtcgccggtt atcatacttg tatggatgtt ttgggattta aagtaggaaa ttacttgttg
    25081 ggtatttgct tttggaatat ctagcagacc taaaacagca attaactgct gatctttaga
    25141 aagataaatc acggttttgc cttgattttc caaacgttcg atcatttccg caatctcttt
    25201 gctgattatc atcgtctcag gatcatatgc gtgcttgcca actttccatt gcgcacctaa
    25261 ataggtagtt tgtaatccaa aaccagtaat ttcttctatt ggtaagtatt ggatttcttc
    25321 aggtattgtg caatcgaaat attgcaaaat cgcatgagca agtggatgcg tcgttttttg
    25381 ttccatagca acaagaagtt gttgtgccaa atccttttca tcaaagaaaa agctgtcagt
    25441 tacaactggt tttcctttag tgagcgttcc tgttttatca aaggcaatcg cttttaattc
    25501 agaaagcttt tctaaatgga taccgccttt gattaaaatc ccattttttg cagaatttga
    25561 aagagcagct agagaagctg gtgtagcaga tgcgacaagc gcacaaggag aagccacaac
    25621 taataatacc attcctcgat aaaagctttc atcccaactc caacctagga aaaagtgggg
    25681 gagaaggatc attagaggaa cagcaagcaa aatcaatttt acataattat tttcgattcg
    25741 ttcgataaat gaagctgttt gagttggcgt attctgcgct tcttctacta attggataat
    25801 cttagcaaag acagtttcgg aactcgtttt tgttactcga atcgtgatgg gatttccttg
    25861 attcagcgtt cctgcataca tctcatcgcc taaatatttt tctacaggca cagattcacc
    25921 gcttaatgca gactcatcga tcgttgcctg tgtgctttct aaaaagccat ctatcggaac
    25981 agctgctcct ttagcgacaa ataccaagtt atccaccttt agttgagaaa catctacttc
    26041 ttgcatttgt ccattttctt ttaataattg ggctttttgt ggttgaagat tcatcaaagc
    26101 agtaatttct ttttgacttt tattagttgt gtattcctct aatgcaccgc ttaaacaaaa
    26161 gatgaatgtc aacattgctc cttcaaagta attaccgatc aaacaggcac caatagcagc
    26221 taaagccatc aataaatcca cattcagtgt ccgatcattc cacaattctt tcaagccttc
    26281 cgatgtttgt ttatatccac cgatgataat ggcactgata taaaaaagtg gggtgatggt
    26341 aagagagaat cggtcgaaga taaaaccgaa gatcataaat aaaaggcagc cgattgttgc
    26401 tgcaaaagct tttttctgat tagtcatcgt tattagacct ccttgtcaaa acaaggatag
    26461 cataataaaa atgtaattga taataataac agctaaatga gaacgataat ggttatcatt
    26521 tggtgattaa gcttgatgtt gtttttatta tttataatga ttattattaa agaaaataaa
    26581 aaaccagaac atttctcaaa taagagaagt gttctggttt tttctacatt gcaataaacc
    26641 aataaccaat caaaatgata ccaaggataa tacgatacca gccaaaagcg gtaaagtcgt
    26701 ttttcttcaa atagcttagt aagaatttga tagctaagac ggaaaccaca aaagatacga
    26761 atgttcctac aagaagaaca acagtttctt ccattttgaa tgaattccct tcagctaaat
    26821 atttgacgat cttcaagccg cttgcgccaa acatgacagg aatccctaag aaaaatgaaa
    26881 actctgtagc gacaaaacgc gaagcaccaa tcaagataga tcctaggatc gttgcgccag
    26941 aacgggatgt tccgggaaca agtgccaaga cttggaataa cccaacaaga agagctgctt
    27001 ggtacgtaaa gtcattcaga gaagtccaac gaggtgtttt gtttttgttg cgtttttcga
    27061 caataataaa ggcaataccg taaacgatca aaacaatggc aactggtaag aacttgtgga
    27121 aatttgcttc taaccaatca tccaaaggca aaccaatgat gatggctggt atgcaagcaa
    27181 cgatcacttt aaaccaaagt gtccacgtat cttttttttc taccgttgat ttacttggag
    27241 aaaatgggtt taacttgtga aaataaagaa cgacgacagc caagatcgcc cctaattgga
    27301 taacgacatt gaacatcgac ataaattgtg aactggcatc cagtttgatg aattcatctg
    27361 ctaggatcaa atgaccagta ctactgatgg gcagccattc cgttattcct tcaataatac
    27421 cgagaatcac tgctttgata atatttgcaa aaaacataaa ttccttcctt cccaattaag
    27481 atacatctta tagtataccg ttattttttg agaaacccaa tctgtttttt aatattaaga
    27541 aaaacttgag aaataaagca gataagtaca cgaagagaaa aaagaagaca aagccctcgt
    27601 tcagactttg ccttttatga ttctctggta aaaattaaaa tatccccatt atagaaacga
    27661 gtcgcgacta tgtgttttcc cgttatcgat ataagacgta tcattgatgc cgtggataga
    27721 aaatcgaccg tttgcataag tgacctttgt tacgctgcca tttaaaagcc cagcacgaac
    27781 aggctgttta ggatcgatca gattaagcaa aaaggcgatc gtcaaaccat gagatacgac
    27841 taaaacattt ccaccaccat ttttttcgca gtgatgggcg atatcttcaa atcctgtcca
    27901 tacacggtct cgcaatgttt cataagtttc cgcccaccca gcggtatcta agttgtatac
    27961 agcattagca atttgttcaa aagaaacttc tgtggtaaac atttcatcat atgttttaaa
    28021 attcaataca cgagggatca caccccacat ttccatgtca tatccacctt caagagaccc
    28081 gaaacaccat tctctaatcc ttttttcaat aaaataagga atttcttttc ccttagaatg
    28141 ttctcctaga ataatacggg cagtttcgat tgcacgacca ctgtcactag aataagcaaa
    28201 tgaaaagtcg acatttttta acccgcgacc taaataatga atgccttctt gtccttgctt
    28261 tgtgaggggt gtatcacacc agccttgtac tcgttcaatt gtattgaaca tcgtttttcc
    28321 gtgtcgtacg atataaagtg tagtttctgt cattttattc tcctcctaag tcgttttaac
    28381 gattgaaaaa aggatttgtc cttttttcct gttcaatcgt cgttgcatcg ccatgtcctg
    28441 gatagactgc aaattcatca ggtaatacaa acagctgggt ccgaatacta tgaagtaatt
    28501 gttctaaatt ccctgtatac agatcggttc taccgatact tcctctaaac agggcgtcgc
    28561 cagaaacgac aaaatcatca aaaataaagc tgacgcttcc tatagaatgc cctggggtag
    28621 ggacgacgcg aaaagacatg tttcctaaag tataagtttt catttcaaat tcatattctg
    28681 caggcgagac aataacatca gcaatatcat catgtctacc gagtccagaa agattcaaaa
    28741 tcggatcacc tagccatttt tgctctagtg ggctgacata aactgggatt tgataatacg
    28801 cgcgtaaagg ttccactgca ccgatatgat cgtagtgagt atgggtaagc aaaatcgcta
    28861 ccggctgttg gtttgttttt ttgatttctt gtttgattcg ttccgcatct tctccagggt
    28921 caatgatcaa aagtgcttct tcgttgtaga ccaaataaca gttttcttca atcattcctg
    28981 tttttaatct ttcgatatgc atgtgcattc ctccttgata gccaaaactt ctttcatcca
    29041 ttagtataac gcattcattg ctaggaaaca aaaacaggta cttatttctc tttacttatc
    29101 tgaattatca gactatatga aaagtatttg gatattctaa agagaaggaa agtaagtttt
    29161 catagcattt taatatgtcc ttgttacatt agattcatcc aaaaatccaa attctatatc
    29221 ctatatccct gcctaatcag cagggtgttt ttttatgttt ggaaagagag ctctttttgc
    29281 taaactaggt tttttcaggt aatcttagag agaaagaggt ggtggaaatg atcaaacagt
    29341 caaaaatatc tgtgcggcac ttagtagaat ttattttgcg acgtggaagt atcgacaatc
    29401 gtaaaaaaag taaccatact gcattagaag gagcgagaat ccaccgcaag ctccaaaaag
    29461 atgcgggaga aaactatgaa aaagaagtct ttttaaaaac aacagttcaa ttagatgaat
    29521 attacctgat cgttgaaggc cgtgcagacg gtattttcaa aagagacggt atttattata
    29581 tagatgaaat caaaacctcc gaaccacgat ttgaagattt agaaccagaa caagtggaac
    29641 ttttctttca tcaagcaagg gtgtatgcct atatctatag tcaagaacat gatttacaag
    29701 aaataaatct gcaattgact tacttccaga cggcagaaga agtgatcacg agaaaggttg
    29761 aacatcagac aagagagcag ttagaaactt tttttaaaaa gctgactgaa gattataaag
    29821 aatggcttgt ttttcaagaa aactggcgca ctgtacgcaa tgcctctttg atggctttga
    29881 aattccccca tgatgagtat aggaaaggtc agcgtgaact agcggtagct gcttataaaa
    29941 cgatccgtac gaaacagaaa ttgtttgtag aagcacctac cggaacagga aaaacaatct
    30001 ctacgttatt ccccgctttg aaagctgtag gggaagaaga gggagaaaag atcttttatc
    30061 taacggctaa aacaataact agacaagtag ctgaagatgc tatgacagca ttaaaagata
    30121 caggagctga agtaaaaagt gtcactttga cggcgaaaga caagatctgc tttttagatg
    30181 agacgacctg taatccagat cagtgcccat atgccaatgg ttattacaat cggattaatg
    30241 aaggtttatg ggatcttttg aatcatgaga atcagatcac tcgtgaagtc atcgaaactt
    30301 atgcaagaaa gcatacactt tgtcctttcg aactatcatt agatgtcagt atctggtgtg
    30361 acgtaatcat tggggattac aattatttat ttgatccaac tgtttattta agacgttttt
    30421 ttgaagatga aaaaaacgag gactatctgt ttttgattga cgaagcacat aatttggtga
    30481 atcgttcccg agagatgtat tcggcagaac tatcttatga aaaaacgaaa cgaagtaagg
    30541 aagctatacc aaaggaattc aaaaaacttc atcgccgttt caacaaacta ttaaaagaat
    30601 ttgattcgat ccgagaaata gcaaaagaag atcattggga ttatcatcat caaaaagcac
    30661 cggctgaatc tttagtaaag gcaggttatc aattaagcga aaaaattaaa gaatggctgg
    30721 cagaatttcc tgagcaccca tcacaagaac aattgcttcc ttattatttt gatttgcttc
    30781 attttttgaa ggtcagtgaa ttttatgatg atcactacga aacaacagtc gaaaaaacgt
    30841 atcgcgatct gatagtaaaa gagttttgta ttgatccaag cttgtttctt gagcagtcgt
    30901 tggataaagg aaaaagcagt attctttttt ctgctagttt ttcaccactc tcttattatc
    30961 aggaaacact ggggggacaa aaaagtctgg cttacaaact gccgagtcct ttcccagaag
    31021 gaaaccagca agttttcatc gcaaattacc tagagacgac ttatcgaaaa agggaacaca
    31081 gtctggcaaa attagtagag acgattcatg cttttgctga tggaaaggtc gggaattatt
    31141 tcgttttctt tccttcttat caatatttag atcttgcggt ggaagcattc agacagcaat
    31201 atcccgacag caatgtgcta atccaagaaa cggacatgaa tgaggaagaa cgcgaacgat
    31261 ttttaacaaa atttcaaaca aatcccgctg aaacattgat tggattttgc gtacttggcg
    31321 ggattttttc agaaggaatc gatttgagag gggaccgatt gatcggcagt atgatcgtag
    31381 gtgtaggttt gccgcagatg aatcatgagc aggaactgat caaatcatat tatgatgaga
    31441 aggaacacct tggatttgct tacgcttatc agcttcctgg aatgaacaaa gtcttgcaag
    31501 ctggtggtcg agtgattcgt ggcatggcgg atcaaggaat cgttgtattg gcagatcaac
    31561 gattttctag tttttcttat cgacgtttat tcccacaaca ttggcaaaca gcaagagaag
    31621 tacgaagtgt tggggaattg gaagaaggaa tacagcgttt ttggttatca aaagaagcag
    31681 taaatcaaaa aaacgaggaa tgacagacgt cagcctcgtt ttttgattaa cgatagttag
    31741 tgaattgcaa ctcgattggt aagtcaagtt tacgtaataa agcaatcaca gcttgtagat
    31801 catcacggtt cttacctgtc actctaatct gatcttcttg gatttgtgct tttactttca
    31861 gtttttcatt tttgatagct gtagtgattt tcttcgcgtt ttcacgatcg attccgttga
    31921 ccaaatcggc agtttgtcga gctttgccac ctagagcgtg ttctgattcg gaaaaatgga
    31981 tatttttgat tggcacattt cttttgatca gcttaccaaa taatacatct ttgatctgtt
    32041 cgattttgaa atcatcatcg ctcaatacaa ctagattgct gttctctaat ttgatttcta
    32101 ctgtagaatc cttgaagtca aagcgattgg acaattcttt tgttgtttgc tgaatcgcat
    32161 tttttacttc ttctgtattg acttctgata caatgtcgaa gctagcatct tttgccatag
    32221 gaaccctcct gatatacata taaatattta ccatacatct atcttatcat aggattaggg
    32281 cagattctta cctgtttgct aaaattcttc tcatttgagt tcgaagtatt ttattttaat
    32341 agataaactg ttattcttac atttggaata ccaaagtagg ggagaggtgc ttgtgagtaa
    32401 aattatgact gcgtatcata aaaatgaaag attaaagaaa atagtggtta ttttgataac
    32461 cggattgacc gctgcggtcg ctttaaatta ttttttgatt ccagccaatg tcttttctgc
    32521 agggatgaat gggatcgctc aaatcatttc ctcgctttta tatgaatggt ttcatatcaa
    32581 gatagacaca ggaacattta tttttctttt gaatatccct gtgtttgtat tagggtttct
    32641 caaagtagga aaacgagcaa cgatccttag ttttgtgaat gttgtatgtg tatcggtgat
    32701 gacgatgctg cttccagtcg gacagatcac tgataatatt ttgatgaatg ccctagtagg
    32761 cggtgtttta ttaggtcttg gcgtaggatt atctttaaaa atgggcttta caactggtgg
    32821 gatggatatc atctctcttg tactttcaca aacaactgga aaaacagtcg gaaactacat
    32881 gctgattcta aatggtatca ttgtagtcat cgcaggcttc ttctttaact gggaaagtgc
    32941 cttgtatacg attatttcca tttatgcaat gactcaagta attgatgcca tccacacgag
    33001 tcatcaaaaa gtaacagcaa tgatcgttac cgtcaagcca gaagaggtaa cagaagaact
    33061 agcaaaacgg atggtacgtg gaatgacatt actgccgtct gtcggtggct attcaaaaaa
    33121 acaagggaac atgatcatga tggtcatcac ccgctacgaa atgtatgatc ttgatcagat
    33181 cgttcatgaa atcgacgacg atgcatttat caatatttta ccaactcatt cagtatttgg
    33241 ccggtttgca aatgaaaacg aacaaaaaat gtatcgaaca actggcgtat tgccagaaat
    33301 aaaaaatcgt tcacaaaaaa aatgaggaat caggtttatt ttagaataaa tttaatctat
    33361 tacatctaat aagaacattt ttataaattt aaacgagaat cttacttcta aattctcatt
    33421 tacaagcagc taaaaaaaga gtatgataaa taaaaatcgt gttaaggagt gtcgtacgat
    33481 gagcgaagca aaccaagaac ggtctggaca agaaatagaa ctaatcaaag aacgtattct
    33541 tgctgccttg gaaatggtga ttgatcctga attaggaatc gacatcgtca atttaggctt
    33601 gatttatgat atagaattca atcctgaaaa tggagaaaca gtcattaaga tgactctaac
    33661 aactatgggc tgtccattag cagatatttt aacagaatct atccatgacg cattaaaaga
    33721 agtgccagaa gtaacgaaag cagaagtcaa actagtctgg tatccagcat ggacgacaga
    33781 taagatgagc cgttatgcac ggattgcgtt ggggatacga tagaaatctt ggctgactag
    33841 ctatgagaag caaataggaa aaacaaaaaa gccttttatc ctttctagaa gaaaagagat
    33901 aaaaggtttc tttgtttata aaattttgtc tgctatatta taagttaatt aaataaatgt
    33961 gttctattga taaaggacat tcaaatccct ttccttttgg aatccttctt ttttacatca
    34021 gtttgatttt cgtatagtat tctttctcat cttcacgata aatcgcagcc ccattttttt
    34081 gttgtgcttt aagactgcca agattttttt tatttacaga caaaagtgcc tcatcaatgc
    34141 cgattttttt tgcctcttgt agtactaatg ctaatccttg tgtggcatat ccttttttac
    34201 gataattagg ggagatgccg taaccaatat ggccagcgcc gtttcttaat gtttcgttca
    34261 gtttatggcg caaattaaaa attcctacat actcatgttc atcactttct aaaataaaga
    34321 cggttgcggg aacgtaactc tcaggaagat cgattcctaa agacgttttt tcgcattttt
    34381 ttacataatc taaaaattca gcaaatgtat agccataagc attgttgata aatccactct
    34441 catttggtcc aaagctagtt tgtagctgat aagctttctt taaatctgct tcccatagtt
    34501 tgatcagttt catcgtattc acctctttaa gtaaccttat tcatttgttt tctactatag
    34561 cactattgtt gtaaatagcc atgcctattt ttatttattg tgtcatatcg tattaagaat
    34621 catcgaacaa tacaaatatg aattacaata aaaaaattat ttgaagttcg ttcattcgtt
    34681 acttatgatc tctagaagaa agaaaacgtg aattacttca gcgtctagaa ttccagaagg
    34741 atagtaatca acagaagaaa taatcaatat ccaaatgaaa gaagatagct gaatcgagaa
    34801 aaagaggaaa aaagaaatga agaaaaaaat aaaatagtta ctaatcccag agtcgttcgt
    34861 ttaacattga aatcgatcat atggataaaa cagatttttt caccaaccct caatagatga
    34921 tggagttgct cggatgaatt atttgtgtag atggcataag ggagggcgta cagaaatgaa
    34981 aaagaacaaa aatatgttct tgacaaaaaa cacatgtaat cctaaactaa aagatgtgat
    35041 gcggctatgg cggaattggc agacgcgcta gcttcaggcg ctagtgaggg tgacctcgtg
    35101 gaagttcgag tcttcttagc cgcataattt gtttttttat aaagagaagg tacacctgga
    35161 gcgatgagaa agaaaataac atattatcta aaagaatata ggaaaaattt taaacaacgg
    35221 aaccagattc aaataaatca aaaaaaattt gtgtgaaggt gggacagttt aaaacctaat
    35281 agattgattc aaatagtaga tttatagatt ctgatacaag aaatactggc aaacgatagt
    35341 taaggaataa agactaaact taaactcaaa aagaggtcat gcgaaagaat aaatcgcatg
    35401 acctcttact atattttgaa tgtgtttaaa cgttcaaata atgaatctta gtaccaaccg
    35461 tttgcttccc agaatgcttt cgccgcttcc caagaaccat aacgtgaagt aacatattgt
    35521 tctgctactc tttcttggtt tgcagcagag tagtcaccat ttaagtaaga agaatctaat
    35581 tggtaacggc cgatgtaacg tccgttcgtt gctgtgtaag aaccgcttga ttctttttgt
    35641 gcgatccatt cttttgcaga gcttgtactt gctggagtag cagcagtttc tgttacagca
    35701 ggagcaggtt gtgtttcagc aacaggcgct gcttgtgttt ccgtttgaac cgtttcttgt
    35761 acaacaggtt gttcagcttg aacaggttca gcttggactg gtgcttcttg aacggctgct
    35821 tgaggttcag cagctgcttg tgcagagcct tctgttggga ttgttaattg ttgtcctgag
    35881 ta
//
LOCUS       DAFLWQ010000024        35350 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.025, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000024 DAFLWQ010000000
VERSION     DAFLWQ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.025"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            9..731
                     /locus_tag="L1V16_001142"
     CDS             9..731
                     /locus_tag="L1V16_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBN1275496.1"
                     /translation="MLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEPKSIPTTLNVAL
                     IGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGMNKINAAYSYGG
                     VDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSLDLDGVYINKGE
                     QVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFKLPKAVGKLLGS
                     IQTNLPESVLLDCGMDFLKDIC"
     gene            789..2828
                     /locus_tag="L1V16_001143"
     CDS             789..2828
                     /locus_tag="L1V16_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBN1275497.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFQTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLINPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(2937..4088)
                     /locus_tag="L1V16_001144"
     CDS             complement(2937..4088)
                     /locus_tag="L1V16_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBN1275498.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLEYFTKKVYEV"
     gene            complement(4242..4772)
                     /locus_tag="L1V16_001145"
     CDS             complement(4242..4772)
                     /locus_tag="L1V16_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBN1275499.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(4871..5221)
                     /locus_tag="L1V16_001146"
     CDS             complement(4871..5221)
                     /locus_tag="L1V16_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HBN1275500.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(5378..6907)
                     /gene="ahpF"
                     /locus_tag="L1V16_001147"
     CDS             complement(5378..6907)
                     /gene="ahpF"
                     /locus_tag="L1V16_001147"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBN1275501.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(6917..7480)
                     /gene="ahpC"
                     /locus_tag="L1V16_001148"
     CDS             complement(6917..7480)
                     /gene="ahpC"
                     /locus_tag="L1V16_001148"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBN1275502.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(7624..8286)
                     /locus_tag="L1V16_001149"
     CDS             complement(7624..8286)
                     /locus_tag="L1V16_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1275503.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            8470..10116
                     /locus_tag="L1V16_001150"
     CDS             8470..10116
                     /locus_tag="L1V16_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBN1275504.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            10107..11189
                     /gene="uxuA"
                     /locus_tag="L1V16_001151"
     CDS             10107..11189
                     /gene="uxuA"
                     /locus_tag="L1V16_001151"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBN1275505.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNEYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(11297..12850)
                     /locus_tag="L1V16_001152"
     CDS             complement(11297..12850)
                     /locus_tag="L1V16_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBN1275506.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            12998..14166
                     /locus_tag="L1V16_001153"
                     /pseudo
     CDS             12998..14166
                     /locus_tag="L1V16_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(14292..15371)
                     /locus_tag="L1V16_001154"
     CDS             complement(14292..15371)
                     /locus_tag="L1V16_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1275507.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(15474..15914)
                     /locus_tag="L1V16_001155"
     CDS             complement(15474..15914)
                     /locus_tag="L1V16_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1275508.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(15971..16381)
                     /locus_tag="L1V16_001156"
     CDS             complement(15971..16381)
                     /locus_tag="L1V16_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBN1275509.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(16561..16995)
                     /locus_tag="L1V16_001157"
     CDS             complement(16561..16995)
                     /locus_tag="L1V16_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1275510.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(17095..17943)
                     /locus_tag="L1V16_001158"
     CDS             complement(17095..17943)
                     /locus_tag="L1V16_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1275511.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            18332..20098
                     /locus_tag="L1V16_001159"
     CDS             18332..20098
                     /locus_tag="L1V16_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBN1275512.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            20200..21459
                     /locus_tag="L1V16_001160"
     CDS             20200..21459
                     /locus_tag="L1V16_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBN1275513.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            21606..22907
                     /locus_tag="L1V16_001161"
     CDS             21606..22907
                     /locus_tag="L1V16_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1275514.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            22910..23761
                     /locus_tag="L1V16_001162"
     CDS             22910..23761
                     /locus_tag="L1V16_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1275515.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            23774..24589
                     /locus_tag="L1V16_001163"
     CDS             23774..24589
                     /locus_tag="L1V16_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HBN1275516.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            24740..25906
                     /locus_tag="L1V16_001164"
     CDS             24740..25906
                     /locus_tag="L1V16_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1275517.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            26136..26783
                     /locus_tag="L1V16_001165"
     CDS             26136..26783
                     /locus_tag="L1V16_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBN1275518.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            26867..27811
                     /locus_tag="L1V16_001166"
     CDS             26867..27811
                     /locus_tag="L1V16_001166"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HBN1275519.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            27946..29397
                     /locus_tag="L1V16_001167"
     CDS             27946..29397
                     /locus_tag="L1V16_001167"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBN1275520.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            29418..30254
                     /locus_tag="L1V16_001168"
     CDS             29418..30254
                     /locus_tag="L1V16_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBN1275521.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            30254..30913
                     /locus_tag="L1V16_001169"
     CDS             30254..30913
                     /locus_tag="L1V16_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBN1275522.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            31039..31728
                     /locus_tag="L1V16_001170"
     CDS             31039..31728
                     /locus_tag="L1V16_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275523.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            31734..32690
                     /locus_tag="L1V16_001171"
     CDS             31734..32690
                     /locus_tag="L1V16_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBN1275524.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            32734..33246
                     /locus_tag="L1V16_001172"
     CDS             32734..33246
                     /locus_tag="L1V16_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1275525.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(33502..34050)
                     /locus_tag="L1V16_001173"
     CDS             complement(33502..34050)
                     /locus_tag="L1V16_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1275526.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(34139..35320)
                     /locus_tag="L1V16_001174"
     CDS             complement(34139..35320)
                     /locus_tag="L1V16_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBN1275527.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGLGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
BASE COUNT        11892 a         6434 c         6709 g        10315 t
ORIGIN      
        1 tatctatttt gttactgctt acattagtag ttggctattt ttcgattgag tttatccatg
       61 gattttcgtc tgcaaaacag agttcaactg tgaaaaaggt agagccgaaa agtatcccta
      121 ccacactaaa tgtggctttg attggttcag atgctcgttc gaaagacgaa aacggtcgct
      181 cggattcact tctggttgca caatacaacc agaaaacaca acaagcaaaa ctgatctcta
      241 tcatgagaga ttcatatgtc gatattccag gttacggaat gaataagata aatgcagctt
      301 actcttatgg gggagttgat ttattaaatc aaacattaaa ggaaaatttc aaatttgaag
      361 ctccctatta tgcaagtatc acatttcaag attttatcga ttgcgttaat gaactgtttc
      421 ctggtggagt caagatcgat gcagaaaaat ctctagattt agatggcgta tatataaaca
      481 aaggagagca agtgatggat ggtaatactt tactccagta tgctcgattt cgggaagaca
      541 aagaaggaga cttcgggagg atcagaaggc agcagcaagt gatcaaagct atctctcagc
      601 agctgaaaga cgtaacttca atattcaagc tacccaaagc ggttgggaaa ttacttggta
      661 gtatccaaac gaaccttcca gaaagtgtgc ttctggattg tggtatggat ttcctcaaag
      721 acatatgtta gaataaacag gtataaatag tgaaataaag gaatgacaag caagagaagg
      781 aggaaaaaat gaaaagaagt gacaagcacg gcaaaaatcg aacaggcgct tatattgccg
      841 gcgcagtgat cttaatagca gctgcgggtg gcggttattt ttactaccag cactatcaag
      901 aaacccaagc agtagaagct ggagaaaaga cagttgagca atttgtccaa gctttgaaca
      961 agggagatta taacaaagct gcagaaatga catcaaaaaa ggcggcaaat aaaagtgcat
     1021 tatctgaaaa agagatctta gataaatacc agaatatata cggtgctgct gatgtcaaag
     1081 gacttcagat atcgaatcta aaagtagata aaaaagacga ttctacttac agtttttcat
     1141 ataaagcaaa gatgaatacc tcattaggtg aattgaaaga tctttcttat aaaggaacat
     1201 tagacagaaa tgatggtcaa accacgatca actggcaacc caacttggtt tttccagaaa
     1261 tggaaggaaa tgacaaagta agcctgacca cacaagaagc agcaagaggg aatattatag
     1321 atcgaaatgg tgaaccatta gcaacaacag gcaaactaaa acaattagga gtcgttccaa
     1381 gtaaacttgg agatggaggc gaaaaaacag ccaatatcaa agcgattgct tcctccttcg
     1441 acttaacaga agatgctatc aatcaggcga tttcacaaag ctgggtacaa cccgattact
     1501 ttgtcccatt gaaaatcatt gatggagcaa cgccagaact tccagctgga gctaccattc
     1561 aagaagtaga cggcagatat tatcctttgg gtgaagcagc tgctcagctg attggttacg
     1621 tgggagatat cacagcagaa gatattgata agaatccaga attaagcagt aatggaaaaa
     1681 tcggtcgctc aggtttggag atggcttttg ataaggatct tcgtgggaca acaggtggga
     1741 aattaagcat tacagatgca gacggtgtag agaaaaaagt tctgatcgaa catgaagttc
     1801 aaaatggcaa agatatcaaa ttgacaatcg atgcgaaggc acaaaaaaca gcttttgaca
     1861 gtctaggagg aaaagctgga tcaactgttg cgacaacgcc aaaaaccggt gatcttcttg
     1921 cgcttgctag ctctccaagc tatgatccaa acaaaatgac aaacgggatc tcacaagaag
     1981 attacaaagc ttatgaagaa aatcctgaac atccattcat cagccgattt gcgacaggtt
     2041 atgctcctgg atctacgttt aaaataatta cagcagcaat cggtctcgac aacggcacta
     2101 tcgatccaaa tgaagtgttg acgatcaacg ggcttaaatg gcaaaaagac agttcttggg
     2161 gatcttttca aacaacgcgt gtcagtagtg atgtatcaca agtagactta aaaactgctt
     2221 tgatctattc cgataatata tatgcggcac aagaaacgtt gaaaatgggt gagaaaaaat
     2281 ttcgtacagg cttagataaa ttcatttttg gtgaagacct tgatttgcca attagtatga
     2341 atccagcaca aatttctaat gaagatagct ttaactcaga tatcttgcta gctgatactg
     2401 gatatggaca gggcgaactt ctaattaatc ctatccagca agcagcaatg tattctgttt
     2461 ttaccaacaa tggcacactt gtctatccta aattgattgc agataaagag acaaaagata
     2521 agaagaatgt catcagcgaa acagcagtac aaacgatcgt gccagatctg agagaagttg
     2581 tgcaagatgt aaatggtaca gcacattctc tttctgcttt agggattccg ttggcagcga
     2641 aaactggtac agcggaaatc aaagaaaaac aggatgtaaa ggggcaagag aacagtttct
     2701 tgtttgcttt caatcttgat aaccaaggtt atatgatggt cagcatgttg gaaaataaag
     2761 aagatgatga ttcagcaacc aaacgagcat cggaactatt gcaatacctc aaccaaaatt
     2821 atcaataaaa aattgctttt taagtacagt aaaaggactg tggcgttatc gtcacagtcc
     2881 ttttttcaaa taaacggttt tcacgatgtc tctttcacaa cttctttttg atttactcac
     2941 acttcataaa ctttttttgt aaaatattcg agaacaagtg gagaaataag tgtacttaat
     3001 aaaatcacga taactaaagg tgaatagtac tgtggttcga tcaattgact ttgctgtcca
     3061 atttgtaaaa tgatcaaagc catttctcca cgcgaaatca taccagcacc gaccatcaat
     3121 gaactatgtt gagaaaaacc ggcaatctga gcaccaaaat aacctccaag caatttggtc
     3181 aaaatcgcta caagcgtcaa tatagaaata aagagtagtt gttcactaaa gtcagaaaaa
     3241 tcaacttcta atcctacact gacaaaaaat actggtataa atactgcata tcctaaagcc
     3301 tctacattgt ggtatacttc ttctttaacc tttgtctgac tgacagctat cccagcaaaa
     3361 aaagcaccaa tgacagagct aagcccaaca agatccgcta cgtaagacat tcctaaacaa
     3421 ataactagcg atacgatgat aatagaagaa tttgcgtaca ctttttctgc aaatgaaagt
     3481 aggaaaggcg caatccattt gactaataag aaaataaaaa caaaataaat tagctgttca
     3541 atcaaaacaa gcggtaaaga agcattgcta gaagcttccc ccgttagaaa agataggctg
     3601 aaacttagaa ctaaaacgac taaaatgtca tctaccacag aagcacccaa aattgttgat
     3661 ccttcttttg tattcactac gtttagttct tttaatactt ctactgaaat actgacagaa
     3721 gttgccgcaa gaataatccc aaagaaaatc gcttcatttc ccgaaacttg gaatgctttg
     3781 cctgtcaacc agccaaaaac aaccgggaag atgatcccaa gcaaagcaac gaacatacca
     3841 ggtcggaaat attttttcaa aagagataaa tcactttcca gaccagctaa aaacattaat
     3901 aagatcacac caatctccga aaagtcatgg actagaatat caggtttgac ccaattcaat
     3961 ccagcttggc ctagcaaaac accaacaagt aattgtccaa tcactgctgg gatacctaat
     4021 ctccgcgaga tatgtgagcc aatcgttgtt gaaatcaata tcaggcataa aataccaata
     4081 aattccattc tcatcattcc tttgtataaa atatagcccg aacttagcat aacatacatt
     4141 attgaaaaaa taggaaaata tactcacaaa aaaaccaaca atccaaaaga tttttttgga
     4201 ttgttggttt ttatacggtc tattttaata actaaaaatg attaacgtat agtcattttt
     4261 cttattctga tgaaattgat aatctcctgg atgcccatga aaatcaaaat aaagccgaat
     4321 atttggaata gaagcatcaa acttttgaat ggattgaaca ataagacgaa tccgccaatc
     4381 aacaacagaa tactactata aacactccaa cttttagctt ttgtattcat gctgaagaac
     4441 aactggaaca agctgttgat gataacagct aatccaagaa gaatcggcag gatagaaacg
     4501 attgcaggtg caaaagcata gacgatcaga gctaagatca ggaaaaaaag accactgaac
     4561 agaccgatac tccaagaacc tgttttcctt ttaaaacggt aagcctcaaa aagattcaac
     4621 aacccaagca aaacaagata ggcggtgatc agataaccga taaaatgaaa aacagcagaa
     4681 gggtttagca caatcgcaat cccagaaata atataaacag cagctcttaa taaggcgtat
     4741 ttttgaatat tttgtttaat cgtctcaaac atataagaaa acctcctttg acttatttta
     4801 acgtgaacta gtcattttac caaattaaat gttacaaaat gagcgaagga gaagaatatc
     4861 tctggaaaaa tcaacttctg aggatctttt ccattttttt gccttttgct agctcatcga
     4921 tcattttatc taaataacga atttctttca tcaagttatc ctcgatgtct tctactcgta
     4981 caccacaaac aacacctgta atcaaggaac gtgaaggatt ggggacaggg gcttccgcaa
     5041 aaaattgttc gaaagtcact tgtttttgta gttgatattc tagttctgtt tgggaataac
     5101 ccgtcagcca acaaatgatt tcatctactt cctcttttat acgatctttt ctctccgctt
     5161 ttgctacata cataggataa acgcttgcaa aacttgtcgt aaaaatacga ttttgcgcca
     5221 taatcagtca cctttctttt tttcaaatta tttactactt atagtatata agaaaaagag
     5281 aagaaaaagc gattattcaa aaaaacaaaa aggattgtga caaaattctt gtcaccatcc
     5341 ttttttccgc tctctgactt tttacaatct tcatagctca agtgcgcatc agataatcga
     5401 atgctcctaa agctgcagta gctcctgaac ccattgaaac aatgatttgt ttgtatggac
     5461 tatctgtaca atcaccagct gcgaaaacgc cggggatatt cgttgcgcca tttttctcgg
     5521 tcactatttc atttcttgga ttcatttcga tcgttccatc tagccaatcc gtattaggga
     5581 gtaagccgac tagaatgaat actcctgaaa cagctagtgt atgcatctcc atcgtacggc
     5641 gatcgatata ggagagagat tctacctgat tcgtaccgct gatttctttc gtcgctgcat
     5701 gtttgataac agtgacattc gcaagagaga ctagtttatc ctgtaagatt tgatctgctt
     5761 ttaattctgg taagaattct agaacatata catgttttgc taacccagcc aaatcgattg
     5821 ctgcttcaac accagaatta ccaccaccga taacagcaat ctcttttcct ttaaataaag
     5881 ggccgtcaca gtgtgggcaa taagcaattc ctttattttt aaactctttt tcgcctggta
     5941 cattgataga acgccagtgc gcacctgtcg cgatgatggc ggtttttgct ttaagtgata
     6001 taccgttagc taagccaata ttaataaaat gttgctcttt atttaaggaa acggcctgtt
     6061 gattcatcat aatgtcgata gggtaactac gcacatgact ttctacttgc tgcatcaatt
     6121 ttggaccttc tgtgtaagag gtaccaatca tattttcaat ccctagtgtt tcaacgactt
     6181 gtccgccgaa agaatcagcg acaagtcctg tacggattcc tttacgtgct gcatagatag
     6241 ctgcactact agctgctggt ccaccgccaa ttactaatac atcataaggt tctttttcaa
     6301 acaactcttc ttcaatcaaa gggccagtga ttttttcaac aatttgttcg atcgtcatgc
     6361 gtccgctact aaattcttct ccatttaaaa acacagttgg cactgccatg atttttttat
     6421 catcgatttc tttttggaac atcccacctt caatcatcgt atgagtaata tttggattta
     6481 atacagctaa tatattcaat gcctgtacaa cgtcggggca attatgacaa gtcaagctaa
     6541 cataactgtc aaaatgcaat gtttgtgtta tttttttgat tttaagactc aaagattcac
     6601 tgattttcgg tgcccgtcca ctaatttgta acatagccag taaaaaagag gaaaattcat
     6661 gaccgagggg gataccagca aaaacgattc cactttcttt gccaactgga ttgatagaaa
     6721 aactaggtgt gcgcatcgaa tctctttttt cccaagagat tttaggagac atttctgcta
     6781 tttccttcgt aaattcagct agtttttgac tattttcact attatccaaa ctaacagaaa
     6841 aaacaatagg agattcaatc agtgctaaat attgttcgag attttgttta gtttctttgt
     6901 ctaacatatc caccacctaa atctttccaa caagatcaaa acttggtttc aatgtttcgc
     6961 cactttcttt ccattttgcc ggacaaactt cacctgggtg ggtacgtaca tattgagcag
     7021 cgcgaatctt atcaatcagt gcactagcgt cacgaccgat tccatctgca ttgatttcca
     7081 tagcttgaac gattccgtct ggatcaataa taaatgttcc tcgctgagct aatccttgct
     7141 cttcatccaa aacatcaaaa atacgagaaa tctgatgaga cggatcaccg atcatcacgt
     7201 attcgatttt accgatagca tctgatgtat catgccatgc tttgtgagta aagtgggtat
     7261 cggtagagca agaaaagact tcaacaccta aagatttcaa tgtactgtat tgttcttgta
     7321 agtcttctaa ttcagtagga caaacaaaag taaaatcagc tggatagaag caaagaatac
     7381 tccagttccc cataagatct ttttcactga cttctaaaaa ttctccttga tgataagcat
     7441 gtgcattaaa ttcttcgatt tttttcccaa tcaatgacat agtaaaacct ccaataataa
     7501 ttatttattt ataattattg taatttagtt ggagttgcaa agtcaatgga tattttgtta
     7561 tttaataaag attactcaaa aacgaaggtt aattataaaa atagaagagg tcgcaagaaa
     7621 atgctactgc tggaaatact cgggataacg ttgagtaaca gtttcctgtt ctttcagcat
     7681 catgtgtaag tgcaatcccg tttgaaatcg agcttcttct ggttttttat caactaaagc
     7741 cttgagtaaa tcataatgtt gttccatgat cgtttcccat ggaagcccct gaatggtcac
     7801 tcgtaaccag cggaaacgtt ctaaatgggt attatggtca tctaaccagt tccaaacttc
     7861 ttttcttcct gcaatttcga aacaagcttc atgaaataaa ttatctgcac ggaaaaaagc
     7921 gcgttcgtca tttattttga ctgctttttc ttgttcttct aaaatcgttt ctagcactat
     7981 tcgtgtttgt gtgtccaatt tggaacaaca ttcaatcatg atttgctctt ccaactgttc
     8041 tcggacaaag cgagcatttt ctgcagaaac aagattaatt ttggaaacat acgtaccact
     8101 ttgaggtatc gtatacacga gttcttgctg acgtagttga atcaatgctt cgcgaatggg
     8161 agtccggccg atagcaagat gttcctccag tgccttttca gatattttcc ttccaggttc
     8221 taagtcagca tagataattt gtttacgaat cgcttgataa gcttgtgatt gcaagctgct
     8281 tttcatcttt attcctccaa aatcatttct atgaacgtag tataacagaa gaggtctgaa
     8341 aaacaatctg gtatgtcaca ttaactagta aatttgtata aatagtaaaa ttttggttga
     8401 catagcgatt tttattgtat aaaattcact tgaatacaaa aactaatatg ttagtttagg
     8461 aggggaaaaa tgattgattt aaacaactgg aggaacttta tccctgaatt atctcaaaaa
     8521 gaagtagaaa tacctcattt tgaccgtgca tcattaagag aaaatggaca aaaaaatcct
     8581 gtctggatcc atttcggtgg cggaaatctt tatcgaggat ttcatgcaga aatcgctcaa
     8641 cgtttagcgg atctaggcga attgtccact ggtgtcattg tttgtgaaac attcgatgaa
     8701 gaaataattg aaagggctta ccaagatttt gatgatttga ttcttgaagt ggtcatgcca
     8761 agcagtggag agttcgtcaa acgtatatta gctgcgacag ctgacagtct gtattgtcat
     8821 ccagattgtt ctgaacactt tgataagatg attcgacact ttgaaaatcc tagtttacaa
     8881 ttagttactt ttgctattac tgaaaaaggt tatcgattga aagatacaaa taataaatat
     8941 ataggaccga ttgcagtcga tataaaaaat ggtccaaaga agccatcaca tacaatgagt
     9001 attcttgctg cgctacttta taaacgtttt ttatctggag cttggccgat tgcacttgtc
     9061 tctacagata atttttcaca aaacggtagt caattacgta cttctttgct aacgatcgca
     9121 aaagaatggc aaaaggaagg ttatgtacaa aatacattta tccaatactt atcgaatgaa
     9181 gaaattgttg cgtttccatg gacgatgatt gatcgtatca ccccgaatcc ttccttgtca
     9241 gttagcaaaa tgttggcaaa agagggcttt tcaaatatgt cgattttcca aaccgcaaaa
     9301 ggaaataata ttgctccatt tgtcaataca gaggacatcc attatttaat catggaagat
     9361 cattttccca atggacgtcc gaaattcgaa aaagctgggg tattcttgac tgatcgtgca
     9421 acggtagata aagcagatac gatgaaggtg acgacttgcc ttaatccttt gcatacgtct
     9481 ttagctatta tgggttgttt actggggtat aggagcatag ctgaggagat gaaagatcca
     9541 gatttatcgc tgctagtttc tgaaatcggg tacaatgaag gcctcccagt tgtggagtct
     9601 ccaggtatca ttgatccaaa gatctttctg gaagaagtaa ttactgtgcg cttttctaat
     9661 ccaaatattc ctgatatgcc tcagcgaatc gccacggata cctctcaaaa ggtggcgatt
     9721 cgttatggtg agacgattaa aaaatatatg gaaatagaag ttaaagaccc gcagacactt
     9781 gtattcatac cattgactct cgctgcttgg cttcgatacc ttattggcat tgatgatcaa
     9841 ggaaaaccat tcatcccgag tccagaccca ctattgacag actttcagca taagctttcc
     9901 gatattcaac tgggtacgca agatacatca catattcatg agaaaatggc tcctattttg
     9961 tcaaataaag aaatttttgg tgtagatctt taccaagcag agcttggcag aaaaatagaa
    10021 gaaatgttca tcaagatggt agcaggaccg aatgccgtac gaaaaacatt acaggattac
    10081 ttacaagaac atggaggaaa tttatcatgg aaatgacttt tagatggtac ggatcacagg
    10141 aagaaaagat taccttagat gaaatcagac agattcctgc ggtcaaaggg attgtaggca
    10201 cattgatgga tataccagta ggagaggtat ggcccaggga gaggatcaaa gaactaaaag
    10261 aagaaattga gtctcgtggg ttaacactaa aagtaattga aagcgtcaat gtgcatgatg
    10321 ccattaaaat tggattacct tcccgtgagc agtatatcga aaactataag cagacaatcc
    10381 gaaacttggc agaatatgga atagaagtca tctgctataa ttttatgcct gtatttgact
    10441 gggtgaaatc tgaccttgac taccgcttag aagacggctc atccacgtta gcttttatat
    10501 ctgatgatat tccagatgat ccaagagaaa tcgtcgcgcg catcgaacat tccagcaatg
    10561 aatttgaatt gccgggatgg gaacctgagc gcttagctca tatcaaatcc ttgcttgaag
    10621 cctatgcatc agtagacgaa gaaaaacttc gagaaaattt tgcctatttt ctccaatcaa
    10681 tcatcccaac atgtgaagag gtaggggtca aaatggctgt acatccagat gatccgccat
    10741 actcgatttt tggattacct cgaatcgtaa agaatcgaga agatttagat tggttgtgcc
    10801 gcatagtaga cagcccttat aacggaatca ctctttgtac agggagtatt gcagaagatc
    10861 cagaaaatga tgtatatggg attttagcag aattttgtca aagagatcga atcccatttg
    10921 cacatgttcg aaatattaaa tttttagcta atcgagattt ctatgaggca ccgcataaat
    10981 ccgaatacgg ttcattagac atgtaccgca tactaaaaac aatgtatgac aacggattta
    11041 acgaatacat ccgtcctgat catggaagaa tgatctggaa tgagacagga agaccaggat
    11101 acggcttata tgatcgagca ttaggtgctg tttatctaaa tggattatgg gaagcaatcg
    11161 aaaaaggaaa caaaagtaaa gataattagt gaaaaaaact gtaattttat tatgtaaata
    11221 agaaggatgt tcaaattctt gatacataaa tccggaggtt gttaataagc attcggattt
    11281 atgtatctta tttggtctag gaagtaactt gattttcttt tttcgattga tccatgagtg
    11341 cttcttcttt taattcaaag atatattctg agatcctcat aatcactttt ttccagtctt
    11401 ctggtgtgat gattcctttt aaaatataga tttttttgat atgagaaggc aattgtttca
    11461 aagggcagtc gctgataacg atgttgcagt tctccataaa atcattttgt attttgatcg
    11521 attcatttga aaaaatttgt tctatcttaa cgatcagatc tttactgata taaaaatcac
    11581 gcgtatagtt cacaccaatc acaattcgcg gctgtttttt gtagcgatca tacaaatgta
    11641 ctaggtcttc aaccatccat tgcacatttt ccttttctaa aataactggt aacaagtgtt
    11701 gattttgttc tctgaaatcc atataaaatt gttcaatggc ggtttggact tctttcaaca
    11761 cgctatgttc ttgataaagc atgaaagtag gaaggggcgt atttggttga ttgaagttaa
    11821 gaaatccatt ataaagttta tttcgtgcga atgccaatga gtaaagaatc ttttcttttt
    11881 caggtataaa caaatcaaat acagtacaaa aggactccac catttctctt gaataaagaa
    11941 catgaggaac gtttgctttt tttaaaagtt tgtattgctc caagcttgtt tcttccgatt
    12001 cgattttcgt gatagaaagt cgagctaaaa tattcactaa gatgcgttgt tcgcgacaaa
    12061 ttggcagatt aggtcgcaaa atatctacag agggatcaat aaaaaagtca atatattcat
    12121 actctgtgaa ttctttttgt acgtctttca cagaagttgc aggaaaattc tctttacata
    12181 tttttaatag aaaatataat ttatctatca taccgctatt tagtcggtca agtacttctt
    12241 ttttaaaaaa agtattcatc ataaaagcca ctacttgcgg atcttcatca taaaattctg
    12301 tagcagtact tgaaaagatg ttccaataaa tatctaatgc tgcatattga atttgtacct
    12361 cttttccaga aaaagacttt ctgccattat tagaaaagga gatagacaaa ccgtacaatg
    12421 ctaaaaatgc attaatcttt ttcattttcg tatacaaata agaggcacta tagtttgttt
    12481 gctgacttaa actgataatc gaatttgtct gacagctgaa caaagaagtc aagatctgat
    12541 aactgactga ttcgttgcag tatcttccaa atagacgata atagcagtaa gccggatcaa
    12601 ttccttcaaa attcaacttt aaaaaaggtt tttgcttatc aatatgcagt tctgttagat
    12661 tgagacgctc aaagtcttgt tctaattctt tgatgtatag taaaaaattt gattcagaca
    12721 tatggaaatg atctgctaaa tattgtgtag taataaagaa acgatgttca gataggaaaa
    12781 gaaaaatatc taattttgta ttgctttttt tcttcaagag aaacgtttta atcgcttctt
    12841 gagtttgcat gaaagaggct cctttttact taaattgtta aaacttgaaa atattactgt
    12901 ttttttcata aatttagaca aaaaaacagt aaacatatag gtagaatctc tactatctta
    12961 tttcttgcat acaaaaaaat caaggagtga gagagttatg agatattcaa ccatcttaat
    13021 atcaacattt gcagccttaa gcttatcgct tactataaat cagacagtcc acacagagga
    13081 gatagaaaca gccaaatgga cagaaaccaa gtgggccaac gtcaatcgaa ttacctttca
    13141 ggatgaattt tcatccttca attcaggagt cgcaaaatta agaaaaggac aaacagcgac
    13201 catcaaagca aaaattgact attcaggaga cttagcacct atactacaat cagctgttac
    13261 atttgagaat gttgatcccg ctttgtcgat tggctatgac gagaacactt tgactatcca
    13321 acacaagcaa gcgatattta ccttcaccgt tacattaaat caggacttgt taaaaccagc
    13381 gctttttact gtcaaggtat cagatggact accgaacgat catcatcatt taacgccgta
    13441 tagtcagcgg cagacaattg agcaagattc agctatcgac tcaggaggag atcttgttga
    13501 agaaccaaca gataaaccag aaaatgaaaa taagccagaa gtaccgccta cagaaaatcc
    13561 agacggagaa cagaaaccgg aaatagaacc tggagaagaa cccgatacag aaactcaacc
    13621 agagccagac aatgaatcaa aacctgaaat aacccctgga gaaaaaccag atgtagaccc
    13681 agaagaaaaa ccagatgtga ctccagaacc agatacggat tctggaaacc aaacagtacc
    13741 ggaaacaaat ccagacacag ataatgaaac tgaaaatcca gaaaaaccag aggtagatcc
    13801 agaagaaaaa ccagatgtga ctccagaacc agatacggac gcaagagacc aaggaatacc
    13861 agaaaaaata aacaaaaaaa caattcaaga ggatggaaaa aaagagagta aaaaatcaaa
    13921 tctagcaatt ctaaaaataa atgaagagca gctgaataaa aaatcacgaa tatttgatag
    13981 cgcccaatca gctgaaacct taaaaagtag caaggataca acctttgctg tcctgaaacg
    14041 aaaaataaac agctaccaaa atccggagag tcacaaaaca aagttatact gtggagcgga
    14101 atcattctat taagtatagc aacaatgctt tctgcaaaaa gatttaaaca aaacagatct
    14161 ctctaacatt tgaataatgt ctgtgaacgc atttttcaaa taaaaagaaa tatccagaaa
    14221 atgaccccaa aataccagat tgaaatctga tatttggggt cgttcatact ttatctttct
    14281 tcatatttat tttaagggat atctgtttct tttggaagat ggttcgggat ctttttcact
    14341 ttcaatacat ctaaaaagaa ggtaaagatc ggaatgccga caatcaagcc ccaaacgcca
    14401 aagaaccgtt cgctaacaag taagaccaca aatgtataaa aaatcggcag ttctgttttg
    14461 ctggacatca acttcggatt cagcacataa gactcaatta gatggacaat caaaatcgta
    14521 atcaggatat aaacaacatc tcggatgcct ccttgggaat aagctatgaa agatagagga
    14581 atacaagaaa tgataacacc tgctactggg atcagactta aaatgaaaat catgatcgct
    14641 aaactcagca gctgatgaaa gccaaataca gccaaggcga ttgtagtgag caacgtattt
    14701 aaaagagcga caacaaattg agcttctaat accaaaccaa atgtattgac aaacttatcg
    14761 gcaaaatagt aaatatcttg aaagaaccaa gaaaattcac tttttaaaaa caatcttgag
    14821 aatacaattg tttttttctt ttcaatcata aaaaagaaac ttaagatgaa tgacatagca
    14881 aacgccactg ccatttttcc tatatcctgt aaatagccaa gcgcaatcga agcgccattt
    14941 tgaagctgtt caaaaaaatc gtttcgctca atataagtat ggatatattg taaaacagga
    15001 tctgcatctt ttggctgatg ctcgtaaaaa ttaataacgg actggatcat gtcaaatgtt
    15061 tgatgaataa gcatcgggat atactttgtg aatgccagat agataaggta aacgatcagt
    15121 gtataaatca tgatagctaa aacacctgta gggattcgga caaatcgctg aatgatttga
    15181 acaagatgaa tcatcaaata agtaaagata aatgtgagca aaatggttgt aatcatactt
    15241 ctaactaaga aaagaacaaa aacgacaaat aataaaacag tgagacggcg tattttttca
    15301 ttcgccaaaa aacgctgata aacggtcaaa tcgacaacct ccaaataaca aaaaataaac
    15361 acgttattca ttatatgatg gaatatgaaa ataagaaaga gcaaaaagaa aaaccgctaa
    15421 atgacgttat cttatgagtt ggttttcctc ataaaatcgt tcatctagca gtttcagccc
    15481 tttttctggt cttgatgaaa attatctagc atttttcggg tcagatgttg cagtgtatcc
    15541 aattcttcct gttcaagtgg aagataagac ttgatctttt gtggaatacc ttctgcttgt
    15601 ttttgcaacg cagcaccttg agcagtcagc gtaacattta cgattctttc atcacccgtt
    15661 tcacgctgac gattaatata atttttttct gctaactttt ttagtaaggg agtcagcgta
    15721 ccagaatcca gacacaaatc atttcctagc tctttcactg aagtcttttt cttttcccat
    15781 aaaactaaca tcacaagata ctgggtatag gtaagattca gcggcttgag gaggggagtg
    15841 tagtgtctaa tgatttcttt agaggcggca tataaaggaa aacatacttg attaactaaa
    15901 tatagatctt ccatttttcc acctccgctg ttttactata gtgtatcata gcggatttac
    15961 acaaaaaagt ctattcacta actgctttca gagtaacttc tatatttcca gctgtagctt
    16021 ttgaatacgg acacacttta tgcgctgcct ctaataattc ttgcgtttct tccagagaaa
    16081 gaccttcgat agatccttca atctctacac ctaagacaaa gctcgtttca ctttctgaat
    16141 aaagggaaac ttgtgcactg acagtagaag ccccagagat atttttttgc tgtttgatca
    16201 attctaatgc actgttaaaa catgcactga aaccagctgc aaacaattgt tcagggttgg
    16261 ttgcattttc gacgcgttta ccaggagctg caatattcaa ttcgaatgta cgatcgggat
    16321 tatgcacttc tccagagcgt ccgcctgtgt tgatcatttt cgtagaatac atttttttca
    16381 taaaattacc acctttaatt atattttata caattgaatt ttacacaata taattgtgga
    16441 aagcaaagaa atggattggc ataagataaa taagagaaag cacatgaaac agacgcgctt
    16501 tctcgaatag caaacatata caaaaaatat cagagacaaa aaataatctc atcataaaca
    16561 ttacatatat ttctcaaaaa gttgttttct ttcttcaaaa attacttcac gatggacctg
    16621 atgaagcatc cataaataac caaaaggatc tctgaacatt gagttagtca caccaaagtc
    16681 catcatttct gtcatttctt gaatctctac acagccattt cgtaatgctt tattatgtgt
    16741 gtcctcgata tcagagacga tgatattgaa ccagatcgta tttggatgtt cagcagtagg
    16801 agcagtcaaa ccaagagacg tgttttcatc cagcatatgg aatctcgtac catacaaggt
    16861 aaaaatgact tcattattgc ctctagggta atctgttgcc tcaatcagtt gtatttcatc
    16921 aaagattgtt tgatacagtt ctagtgcttt caaactatca tttaatacaa aatcgatttc
    16981 cgttccttta tgcataaaga tctcctctcc ttttcagtcg aacagttact agattctttt
    17041 attataccag ctaaagaaaa cgcattcaaa aaaatagcgg atttacttac caactcattc
    17101 gattggatga taagtaaatc cgcgtcccat tacttctgct acgctgctga caatgacaaa
    17161 ggcacttgga tcgatttctt ctatcaatgg tttcattcgg gaaaattcat gatcagtcac
    17221 aacgatcaat aaaacctctt ttgactttcg attatacccg ccttttgcct ctagcagggt
    17281 aaggccacgt ccaatctcag cacttaagcg aaggcggatg tcttccaaat aatgttcact
    17341 catgaccata acagatttct ttcgattgat acctgtttcg atataagtca tgacaattga
    17401 agtgattgca atagataaaa tagcataaag aaactcttct attccaaaaa taaacagatt
    17461 aagagaaaca acgaatgcgt ctgtaaaaaa taagccaatc gaagtattca agtggaaata
    17521 ttttttaaaa atgaggggag ggatcgtcgt accgccgcta gaagagttgt ttttatataa
    17581 aatcgcaact cctaaagcaa aaatcgcact tccaaaaatg acagacaaca accgatctga
    17641 agtaatcatt gtttctggaa ctattgcaat gattaaagga aaaaccaagc ttccgaaaag
    17701 tactttaaaa aagggttttt tacctaaaaa tagaagagct agtaccaaca taacgatatt
    17761 caacactaaa ataactatag ctcggtcaaa gcctaaagca gcttccagta atattcctag
    17821 accgctgaca cctccagcag caatatgatg aggccctaaa aacatattga tagcgactcc
    17881 taatatgaag agggcaaaaa taatcttaat gtatgtccat ataaattgtc tcgtttcttt
    17941 catttattca cttccttaat tcattaataa tactcttatc ttattataac ttacttttca
    18001 ccttaagtta actttaatta ataaaaaaat taggctagtc taaattatta tgtttcattc
    18061 ttctagaata tacttctacg ccaaaaactg ttaaaaaact tttactttag aaaattggag
    18121 aaattgatcg cttaagataa attcaggaca ctaaatagta caggaagtag actaaaactt
    18181 ttaaaagttt taagtctatc tatttggcaa gtttaaaaaa taaaaattcg gtatcaaaaa
    18241 actgttaccg ataacatttt tgaaagcgtt gtcttttgct tctctatcac ttatagtgat
    18301 gacgtcatat taaaacacaa ggaggaaatc aatggataca gctgcaattt atcatcgacc
    18361 ggaaagtgaa tatgcatttc tatatacgaa tacaagattt cgtattcggc ttcgtactag
    18421 gaaaaatgat atcaaaaaag tatatgtgct atgtggagat ccatatacca taacaactga
    18481 aaaatggtat caaaaacaac gaccaatgaa aaaatgtcta agtaccaatg ttcatgatta
    18541 ttgggaaatt gaagtgacga gcgaaacaag tcgcttacag tatgcgttcc atgttgttgg
    18601 ggaagataac acggactgtt tttacggtga tcaaggaatt tttccttatc gagaaaatgt
    18661 gattactgaa ccaaattttt attttcgaat accttatttt catcaaatcg atcgattcac
    18721 tattccagaa tgggtaaaag aaacagtatg gtatcaaatt tttcccgaaa gatttgcaaa
    18781 cggggacaaa gcaaatgacc ccgaacacac tttaccttgg ggaagtaaag atccagaccg
    18841 agaagacttt ttcgggggag atttgcaagg tgtgatggat catttggatt acttgacgga
    18901 ccttggcatc aatggcatct atttttgtcc catatttaaa gccacatcca atcataaata
    18961 cgatacgatt gattattatg aggtggatcc cgcttttggc gataaaaaac ttttaaaaaa
    19021 cttgattgat gaagcacata aaagagggat acgtatcatg ttcgatgctg tattcaatca
    19081 tatgggtgtc cattcaccac agtggcaaga cgttctcaaa aacggagaaa aatcgatcta
    19141 taaagactgg ttccacatcc gttttttccc agtagattct tatcagatga ctgacttacc
    19201 agaaactgct gaaaatatcc catatgatac ttttgctttt actccattca tgccgaaact
    19261 aaatacagca aatccagaag tgcaaaaata tttgctggat atcgcaactt attggataaa
    19321 agaattcgat attgatggat ggcgtcttga tgttgctaat gaagtcgatc atcatttttg
    19381 gaaaaaattc agagaagcag ttacagaaat caaaccagac atctatatcc ttggagagat
    19441 ttggcattcc tctcaagctt ggctgcaagg ggatgaattc catgcagtga tgaattatgc
    19501 atttacagat tcgattaaag attattttgc aaaaaagaaa atcacagctt cacaaatggt
    19561 cagtggaatg aatcatcagc aaatgcttta cagagatcag gtgaacgaag gaacattcaa
    19621 cttattagat tctcatgata ctgccaggat cttgaccctt tgccaaggta acaaagaatt
    19681 gatgaagtct gtgatggcct ttatgtttct tcaaaaaggg tctccttgta tctattacgg
    19741 gacagaaata gggatgactg gtgaagatga cccggattgc cgcaaatgta tgatatggga
    19801 gaaggaggaa caagatctag agctattcgg ttttataaaa gaacttgttt ctctaaggaa
    19861 acagttgtct aagattattt ctgaaggttc tactcagtgg ctaatagtaa atgatcgtga
    19921 agataagctc tatttcacac ggaaactaga gggacagatc atctatgttt actttaatca
    19981 gtcaaaagaa ccttgggtag tagaacagga aaatgaggtg attcttagtc aaaattgtca
    20041 gttgttagaa gacgggaaag cagagatacg acaatacgga tttttgatca tgtgttgaaa
    20101 actgttaccg gtaacaacaa gaaagcgttt gcaaatgaag atttgtgccc attataataa
    20161 gggtgtaaca gcacgttgaa tacaaaggag gaaatgaaga tgaaaaaaag aagtgtgaaa
    20221 cagttgggtt tagggttaat ctctttagga atcttaggcg gattagcggc ttgtggcaat
    20281 ggtaactctt cagcagaagg ggaagccgat gaaggaaaaa cgttaacagt ttccgttgat
    20341 tctggatata aagattatat aaacgaaata aaaaacactt tcgaaaaaga aaacgatgtg
    20401 aaaatcaagc tagtagaaaa ggacatgttc gatcagttgg aatcattagc gttagatggg
    20461 cctgctggaa agggacctga cgttatgatg gcagcatatg accggatcgg tgcgttagga
    20521 cagcaaggac atctggcgga agtaaaactg ggaaatgaag cagcttacga tgaaacagac
    20581 aaagcccaag tgacttatga tggaaaaatc tacggagaac ctgcagtaat cgagaccctt
    20641 gttttgtact ataacaaaga tttagtcgat acagcaccat caacgtttaa agatttggag
    20701 aatctatcca aagacagtcg ttttgctttt gagtcagaag caggaaaaaa tacaggattt
    20761 ttagctaaat ggactgactt ttattattcc tatggtttaa ttgcaggtta cggtggctat
    20821 gtatttggtg atgatggcac aaatccttca gatatcggtt tgaataatgc aggtgctgta
    20881 gaaggaatct cttatgcaac agattggttc aaaaatgttt ggccaaaggg aatgcaagac
    20941 ataaaaagtg caggagactt cgccagccag caattcatgt ccaataaaac tgcagcaatc
    21001 attgacggtc catggcaagc gcaaacatac aaagaaaaca atatcaatta tggtgtagcc
    21061 aaaattccta ctctaaataa tggacagcct tatcaaccgt ttggcggagg aaaaggatgg
    21121 gtagtcagca attatgctaa aaacaaagac ctctctcaaa aatggcttga ttatgtaacg
    21181 aatcaggaaa atcaagaaaa attctttgaa atggtaaatg aaatccctgc aaaccaacaa
    21241 gctagggaaa cagcaaaggc taaaaacgat gaattaacaa cagctgtgat tgaacaatat
    21301 gaaacagctc aagcgatgcc aaacatccca gaaatgggcg aagtttggac aggtgcagaa
    21361 aacttgatgt tcgatgcagc atcaggttca aaaacaccaa aagaatccgc agatgaagca
    21421 gtaaaaacaa tcagtgaagc catagaacaa aaatactgat taaaatgata accgtccatt
    21481 tttataaaaa atggaacagg tgcttcagat aaaagtggca agagcgagat ggaaaattat
    21541 cttgctcttg ttgccattat cttaaaagca gtttgcggtt tagcaagttt agagggggca
    21601 ttcagatgca gcaagataaa acaagcaata tcaacgaaaa aaaaatcacg ctttgttcac
    21661 ttattccagg gatggggcag tttgtaaatg gccaagcttt taaaggtatc gtttttttcg
    21721 ccatattcgt cctattcatt ggtcagatgc ttctgggcgg atttcatgca ttggtaggat
    21781 tggttacttt gggaagtata ccaatggaag atcattcatt atttattttg attgaaggca
    21841 ctttgcaatt catcattaca atcattttct tgatttttta cggtttgaat cttttagacg
    21901 cttatcgagt agcgaagatg cgtcaagagg gcaaaaaaat caatcggacg atgaaggaag
    21961 tcatacataa tataggtgat gaaggttttc cttatctatt gacacttccc gcttatcttc
    22021 tcatgatttt tacgatcatt ttcccagtcc tagttacatt gttcactgca tttactaatt
    22081 atgacttcaa tcatattcca ccagccagtt taattgattg ggtaggggct aaaaactttt
    22141 ttagtatctt ctttttaagc tcatatcgta atactttttt tgcagtcttt tcgtggaccg
    22201 tgatttggac tttatgtgca acaactttgc aaatcaccct tggtattctc acagcggttg
    22261 ttgctcacca gaaatttatt aaattcaaac gtattttcgg tatcattttc ttattaccat
    22321 gggcggtccc agcttttatt actatcatga gtttttcgaa tatattcaac gatagcgtag
    22381 gtgccatcaa tactcaagtg attcctttca taaaccagct tccttttgta gatatcagtg
    22441 caatctcttg gaaaacggac ccgaactgga cgaaagtagc aattatctta gtgcagggct
    22501 ggttaggatt tccctatatc tatgtgatgg ttacaggaat cttacaatcg atttcagaag
    22561 acttatatga agcagcaaaa atcgacggag caaatgcatg gcagcgcttt tcaaacatca
    22621 cgcttcctgc tgtcttccta gtggcagcgc caacatttat tacacagtat acggggaatt
    22681 tcaataattt ctccatgatc tatctgttta acaatggcgg tcccggaagc gtaggcggag
    22741 gagctggttc tactgatatt cttatttcct ggatctataa acttacgact ggaacttctc
    22801 cgcagtattc tatggcttca gcaatcacgt tgattatctc cgtcatcgtt atctgtgtgt
    22861 cattgctggt atttaaaaag acaaatgcgt tcaatatggg ggattaacaa tgaaaaaatt
    22921 tcattcgagt gctcgattcc aaaaacgact ttctcacttt tttacttact tttttctttt
    22981 aatactgtca gtcattatca tctatccgct tttgatcaca gcaagtactg ccttcaagtc
    23041 aggaaatatt gcagctttta gtttagatct ttcaagtgac tggactttag gaaactttac
    23101 tcggctattc agtgaaacac tttacgggac ttggtataaa aatacattga tcatttctgt
    23161 cctaacaatg atcgtacaag tgactgtagt aactttggcg ggctatactt atagtcgcta
    23221 tcgttttatc ggccgcaaat caagtttgat gttcttttta gtgattcaga tggtaccgac
    23281 tatggcagca ttgactgcct tttatgtcat ggctttctta ttagaagcgc tcgataagta
    23341 ctggttcttg acaatgatct atataggcgg tggaattcca atgaatactt ggctgatgaa
    23401 aggatacttt gacactgtac caatagattt agatgaatct gctaaacttg atggggcagg
    23461 gcatttcagg atttttttcc agattgtatt accgcttgtc aaaccgatgc tcgccgttca
    23521 agcattatgg gcttttatgg gaccttttgg ggatttcatg ttagctaagt tcctgcttcg
    23581 aacacctgaa aatcagactg ttgctgtcgg cttacaaaca tttatttctg atgtgacaaa
    23641 ccaaagagtc tctctttttg ctgctggggc aattttgatt gcactaccga tttgtctatt
    23701 attcttcttt ttacaaaaga actttgttac cggcctgaca tctggcggaa caaaaggata
    23761 ggagcagagt atcatgcaaa catttccgtt aaactatttt tccgcattac gtacgccaac
    23821 tcaagtgttt gcgggacgca aactattatc atggcctaaa tttttcttga tatttgtatt
    23881 tttagtttcc ttgatggtca tgcctgtgac tcttttttat gccaatcaga tccaagcgat
    23941 tccattagaa caatttctat ccgttcattc gctgatcgat gaacaaggaa cccaaaaatt
    24001 ttctgaactt gaattatctg aaactgggtt acaagcatcg caacaaacga tagctgtgac
    24061 ccctgaaatt ttggtaggtg tgtctttatc tgagaaacaa caatccgatc atggaacttt
    24121 tattgatttt gagaaggaac aatgggtgat ccaacaaaag gataaatctg gtatacgccg
    24181 ctatacgatg aattatagcc catctttcca accagattct gtacgtacgc ccgaagattt
    24241 ccaacgattt ttagaaagag aattttatgc cagtaatcgt ccaacaatca ttttatctta
    24301 tagtttaagt cttggtcttg tcctatttgt catgacgagt ctcattttat tcggggcttc
    24361 ctttttcttg tggatgacaa gaaaaagcca actttcatcc attcatacat tcaaagagag
    24421 tgcaaatttg atgctgaatg ttatgggaat aggttccatg gcagcagcag ttgtagggtt
    24481 tatccacttt gactttatct tgatgctaag tgtccaaaca acgataactg tcttgctgct
    24541 tttatgggtt tttgtcaaaa caagattcaa agataagcgt gtcgaatgac aagtttaagc
    24601 gatttatgcg acaatgaatg tgaaaaaaat gaaaaataaa gtagtttttg aaaaatttct
    24661 gaaaaaatta aacttcttag ttgattcttt tcttttttag tattaacgta atagggtagt
    24721 ttttttaagg aggaaaatca tgttagagaa aactttatac aatcaattat tttcacgttc
    24781 tttctcgctc cctgtcgaag taaattattg ggacggtaca acgaaacaat acggagatac
    24841 ggacactcct ccccaaatca aaatcaatat ccatgaagaa atcccaatga aagagattac
    24901 aagtaacgct tctttggcac taggagaagc ctatatggat catcgaatcg agatcgaggg
    24961 aagtatccaa gcattgatca acgatgctta tcagcaagca aacagctttt tacgaggaaa
    25021 agattatcta aaatggctgc caaagaaaga aaaacatacg aaacaaaaaa acaaagaaga
    25081 tatccatgcg cattatgact taggtaacga cttttataaa ctttggctag atccaacttt
    25141 gacttattct tgtgcttatt tcaatacacc tgaagatacg ttggaacaag cacaaatcaa
    25201 taaagtccat catatcttag acaaactctt tatcaaagaa ggcgaaacgt tgcttgatat
    25261 cggttgtggc tggggaacat tgatgttcac tgctaccaaa gagtataatg tcaaggcaac
    25321 tgggatcaca ctaagtgaag aacaatacga tttgattacc aaaagaataa aagaagaaca
    25381 tttagaagat aaatgccgtg tattattaat ggattaccgc gaactaaaag gcgaaacgtt
    25441 tgatcatatc acaagtgtag gtatgttcga acatgtaggt tctgaaaatc ttgaaggtta
    25501 tttcaaagtg gtaaaagatt tattgaaacc aaaaggaaca gctttgatcc atggaatcag
    25561 ccgacaacaa ggcggtgcga caaatgcttg gatcaataaa tatattttcc ctggcggtta
    25621 tgtccctggt gttactgaat tagttgataa tattacaaaa aacgatttgc aactgattga
    25681 tttggaaagc ttacgtcgtg actaccaatt gacattagaa cattggacaa agaattttca
    25741 tcaagtccaa gatcaagtca cgaaagaaat gggtgattcc ttctatcgaa tgtgggatct
    25801 atatttacaa gcttgtgcag cttcatttga atcaagtaat atcgatgtga ttcaatattt
    25861 gcttgttcaa cctggaaaca atgacatccc aatgcatcgt gcataattga ggcaaaagta
    25921 ctgtttaaag actatttaaa aagaagctaa gttttatgat gctccagaag tgaacttttt
    25981 tgtctaactt ctaggattgt ctctaaagct tagtttcttt ttctttatat tttcataata
    26041 aaagtttggt tctttaattt ttaaacatga cagaaaattt tttcttcgtt atacttgtaa
    26101 tagaatacta ttttataaca aaggggatcg aatcaatgaa aaaaactgtt atttatacta
    26161 gtttatttgc agctttgttt ttagctgctt gtcaatcaaa taccaatcaa ggcacatctg
    26221 ggaatacgtc ttccagtagc gaacagcgct cttcacaggt atcggactcc tcaacaaaag
    26281 caagcacatc ttcgtctagc cagacaaaaa gttctagtga agcaagtact cagtcagata
    26341 tcaaagtgtc tgcagctcgt gcgatcgaat tgttccaaga taaataccca gatactgcaa
    26401 ttactagttt ggaattagat agtgattggg gatcttactt ctacaagata gaaggtgtcg
    26461 atgatcaaaa agaatacgaa gcaagaattg atgctcaaaa tgaaaaaatg gagacagaga
    26521 atccagaaac tctagatcga gatgaacaaa atggtcaaaa gaaaaaagaa gatggtctgg
    26581 atgttgataa attgatcacg attgaggaag cagcaaaaat cgccgtcgac aaagtaggaa
    26641 gcggtacggc aacagattgg gatttggata aagatttagg tactacttat tgggaagtca
    26701 aagtaaaaga cggcaatcaa agtacatcag tcaagatcaa tagccaaaca ggcgaagtac
    26761 tgtcaactga acaagatgat taagaatttc ttcggaaaac aagagttgat ttttctttta
    26821 gtcatgatac actagacaaa ataacttgtt tgaaggagcg atttacttga gtttagaaac
    26881 gacctttgcc aatcatatct ttgccaatcc tttgatgaat gcatctggtg tccactgcat
    26941 gactacccag gaattagatg aactggctca ttcagaagca ggagcattta tcactaagag
    27001 ctgtacgatc aatgaacgaa aaggaaatcc cgaaccacgc tattttgatg ttcctttagg
    27061 gagtatcaat tctatgggac ttccaaactt aggtttttct tattatctag agtatgctct
    27121 tgcgtatgaa aaagtgcagg aaaaccaaaa tcaaccgtta tttttttcca ttgccgggat
    27181 gagtgtccag gaaaacttgg aaatgcttga gaaaatagaa aaaagtgggt ttaatgggat
    27241 cactgaatta aatttatctt gtcccaatgt gcctggaaaa ccacaactag cttacgattt
    27301 tgaggccact tatgaaacac tgaaagaagt attcagcatc ttttctaagc cgctaggaat
    27361 caaattgcct ccttattttg attttgctca ttttgatcag atggctgata tcttgaatca
    27421 gtttccattg acctatgtca atgctatcaa cagtgtgggc aatggtttgt atatcgatac
    27481 agaacaagaa gcagtagtca tcaaaccaaa agaagggttc ggcggcattg gcggagagta
    27541 tatcaagccg actgctttgg cgaatgttcg cgctttttat acacgtttga aaccagaaat
    27601 ccaaatcatt ggtacaggtg ggattcggac aggacaagat gcatttgaac atctgctatg
    27661 tggcgcaagc atgttacaga ttggtaccga gcttcataaa gaagggccgg aaattttttc
    27721 tagaatcata aaagaattaa cgcagattat gtcagaaaaa ggatatacgt caattgacga
    27781 atttaaaggc aaattacgca ccatttcata gcaaagagac gaaggtcatg attgatcttc
    27841 gtcttttttt ataaaaaaca ctcgtctgtt cattcctgtg caagcgtact cattgtatgt
    27901 tagacgaact tgtgggaaaa taacagaggc aaaaaggagg ataatatgaa tgatgcaaca
    27961 gaattagcaa aagagcttaa agaaaaagaa tttagttttc aagaactagt tacggatata
    28021 cagaaaaaaa taaagaagca aaatcatgaa ttgaatgcgt ttgtcgcgct tgaaccattc
    28081 gagagtaatt cccacgagct attgattccc cagtcagaaa aagggccatt ggctggtatc
    28141 ccatttcctt taaaaatgct cggtcaagaa aaaaagggat ggctagctac ttcaggatct
    28201 cgtttatttg aaacacaccg agcttctcat acatctaatt atgtgcggca agcagaagcg
    28261 ataggtctag ttccttttgg acaaaccaat gcgccagagt ttggtttcaa aaatattaca
    28321 gacccagtca tctatggccc agcaagaaac ccttggaacc ttgaatgtac accgggcgga
    28381 tcaagtggag gagctgctgc tgcagtttca tcaggaatcg ttcctttagc tggtgctagt
    28441 gatggcggtg gttctattag aatacccgct tcgttttgcg gattgattgg gctgaaacct
    28501 tcgcgaggga cgatgccagt tggtccatat gcttggagag gatggcaagg agctgctatt
    28561 gatttcggct tgacagtttc tatgagagac acggaggctt tattttatgg gatgagaagt
    28621 atccattccg gtgcgccata tcaagtatcg ccagttgagt ggcaaacaca tccaagaaaa
    28681 aaacggttga agatagcttt ttgtgttgat tcaccgatcc actcacagat tagtgaagag
    28741 gcagtacttg ctgtaaaaaa agctgtagat ttccttggaa aagaagggca tgatttgaca
    28801 gagattcctt acccactaga tggtcgtaaa ctgatcacgt cttattatca gatgaatggc
    28861 gcagaaacag cagcaatgat ccgctcgatt gaaacaggca tccagcgagc tgtcagaaaa
    28921 gaagaacttg aacccatttc ttggactttg ttccaatatg gtcagaagct ctctgccgct
    28981 acttacatcg attctctgca tgtatgggat gaagcagcaa ttgtcatgga aaacctacat
    29041 caagaatacg atctattcct ttcaccaacg actgcattta ccgcccctaa aatcagcgaa
    29101 gatttgcaaa gtgatgcgat aagagcacag atggaacaca tcagtgattg ttctgaagta
    29161 gaaggtttag acgttgtttc ttccatgttt gaggagagct tgaagatcac accttataca
    29221 cagttggcta atctgactgg acaaccagca atcagcttgc ctactcattt gacaaaagaa
    29281 aacatgcctc taggaatcca atttatggct gccagaggaa gagaagattt gctatttcaa
    29341 atcggctatc tatttgaagc aaatcatcag ttccatttac caaatccatg gaaatagcag
    29401 aaacaaggag aagaagaatg aagaaaaaaa gattgtttgc tctaataact agtgcctttt
    29461 ttattttaag cgcttgcggt acagctgccg ctaatcagga agataacagc tggagtaatg
    29521 tagaaaaaaa gaaagaatta gtagtagcga cttctggcac actgtttccc gcatcttatt
    29581 ataatgatca aaatgaatta gttggttatg atgtagattt ggcaaaagag gtggctaaac
    29641 ggttaaatgt caaaatctcc tttaaagaat acaacgtgga tggacaaatc acttctgttt
    29701 caaaaagaga atcagatttt gctgcgaacg attttggtat cacaaaagaa agagaaaaaa
    29761 aattctccct ttcagagact ttcaaatatt catttgacag tatgatcgta cgaaaaaaag
    29821 atgattcagg aatccactca cttgaagatc ttaaagggaa aaaagcagct ggcgaaccca
    29881 atactagcta tatgcgttta gcggaaaaac acggagctaa attagtcaca tatgacaatg
    29941 ccacgaatga tcagtattta agcgatgtag caaatggtcg aacagatgtt attctaaatg
    30001 attattatct gcagaaaatg gccgtatctg ctttaccaga tatccctgta aaaatactgg
    30061 agaacgttta tttcaatgaa aacgaaagtg gttttttatt gaaagaagga aatgatgctc
    30121 tgaaaaagaa aatcgatggc gtattaaaag agatgaaaga agatgggacg acaaagaaaa
    30181 tatctgaaaa atattttcaa actgatgttt cagtcaaacc gaaagaaacg atggctgagt
    30241 cggtgagtga gtgatgtact ttcctctaat tgatttttcc ctcatgtgga cttcacttcc
    30301 tttcgtactg caaggcttgg tatacacatt agggattggc ttcgtgtcgt ttcttttagg
    30361 aaatctggta gggttgcttt tgacagtttt aggtcttttg gattggctgc ctctgaatgt
    30421 atttattcgt ttttatttat cgttctttag aggcattccc gcactagtcc tgctgtttct
    30481 gttatatttt gggttacctt atcaattaag tgccttaacg gcttcagtca tctgctttac
    30541 gattaccagc agtgcattta ttggtgaaat ctatcgagga tcactagcag gcgtttcttc
    30601 aggtcagtgg gacgctggtt tagcttctgg tttttctttc tttggggtat tgaaatatat
    30661 cgttttgccg caagcttttc gaatctcagt accggcactc agtaacgtag ctatggatct
    30721 agtgaaaggt acttcgttag cagcaacaat cacagtgcca gaaatatttc aaaaagcaaa
    30781 gatcataggc ggtcggacat tcgattattt ttctctctat attttagttg cactgattta
    30841 ttgggtcatt tgtatcggga tcgaaaaagt gcaacagtat ttagaaaaac gttctatgca
    30901 tcagtcaatc tgaaaaatag aaatggtgct agcgtggctg gcaccatttc tattttttgt
    30961 ttcttgtata ttctgcctag tattttaaaa ccatttcatg taaaatgtaa atcgaaaata
    31021 tgttcggagg tagaaaacat gaagaccccg ctaaccatcg aaatagaatc ctcgttatac
    31081 caatattgca tcgagcaagg cggcttggtt gtagaagaag tcacgatgcc tgatgaccaa
    31141 ggaattgtag atacgcttag ctgcttgaca aaatttgatg gaagccgaga atggcgatgc
    31201 tatgagctga aagtgacaaa agcagatttt cgctctacag ccaaactgtc atttgttgga
    31261 cattataatt attttgtttt accaagtaaa ctatatgaag aagtaaaaac tgaaatccct
    31321 acaggaatag gtgttttagt gtatcgtccg tacacggttg aagaggagat gcctgcctct
    31381 ggtacatttc tgattgcgaa aaaagcagca aagaaagagc ttgctgtacc ggaagaagct
    31441 ttgacaaacc gcttcatggc ttctttattc agggaagtaa gaaaagcaaa gcaaatggag
    31501 cgaggcgtaa aatattttcc aacagatcaa ttgtacaaag aattgaaaag acgttcagaa
    31561 aatcaagatc cattttctaa cgaacgatat tatgaacggt ttttagagga aatagctagt
    31621 caggcaatca atgagttgca agaagaagtt atcgcgcttc agcatgatta tgaatatttg
    31681 aggcaacaac agcagatccg tcggttgcct acagagccat tggagtgaaa aatatgtact
    31741 atccttattt aagaggaaaa caatttgacc tattagcatt aaaagaagca ctgtcgcgag
    31801 gattgctctc caataaaatc caaccagtga tcgaaccagt acgtgattcc gctacgctta
    31861 aaaatgtgat cgaattattt caaaaaaagc accatccaat cgctgtgatc caaaatcccc
    31921 aagtaggaca attcaaatta ttcgatcagc atgtgcacag ttggacagtc aaagaaaata
    31981 gctctgtcgt ccctgcacag atcttaacgc cagaaaatct cagtgaagta ctggattcac
    32041 ctccagcgtt tcttgttttc gatggacagc actacccaaa agatacagag gtgtggaaac
    32101 agttggcagg agttgattcg aaatttttga taccagatac tagtcgcttt cgcatctggc
    32161 tgcccgaaaa caaaattgtg atccgtgact cttttcaaac gagaaagcat gttgaaagtt
    32221 atgcagataa aacagatgac ttttttagtg atgactatct ttttttccac gcagacggat
    32281 atattggatt ttctgatttc acgatcgaag gtagccgtta tttcgataaa gggttcccta
    32341 gccgagcgct tgctatccat ctaacgtata ttgatgctta cggcaatata cgcgtgaaac
    32401 attttgtctc tgacagtaac gactctgcta aagaccaagc attgaagttt cttgaagcag
    32461 gagataaaat gaaaaaatgg atcatgcgtc accatcatca actcttgatt acttcaggaa
    32521 tgattgaatt attggctctt taccagcaac aaaaattccc tggactggga gtgttgaaaa
    32581 agtggtcact tatgcatcat ttggaactta ttagtcacct gctagatcat ccaaaagatt
    32641 ggcttaaata ttattcaaaa gttcaggaac tatatgaagt gatccaatga ttagataatg
    32701 taaatgaaaa aggaatagaa aagaggaaac tggatgtata ttcggcaaac aaggaaagaa
    32761 gaagtagaag aagtggtaga aatcattaat gccgcagcgg atttcattgc ttcgcaaggc
    32821 tctcctcaat ggcaaaacgg gcagaaacca acaaaagaaa cgattttgaa cgatattgaa
    32881 agaaaagaaa gctatgtatt aatagtggaa gatcaaattg ctggaacagc tgcattagtc
    32941 tcaagcgtgg atcccgttta cacaaaaata gatggtagtt ggaaagaatc aactggtcct
    33001 tatttatcga ttcatcgtgt cgctttagca gaaagtactc gaggaaaaaa actagcaaaa
    33061 ccgttcttag aacatttgtt gacgattgca gccagcaaaa atatccaaga tatccgtatc
    33121 gatacttatc cagctaatga accgatggaa aagaccatct attctgctgg attcacttat
    33181 caagggatga ttgaatttcc ttttgaacac ggcgaaagaa aagcatatca aataatcatc
    33241 aattgactat aaaatcatct gagcaaagat aaagacatta acactactga aaaaaacaat
    33301 catatgatag ccaagaggtt gtaacagaag tggccagctt caaaaaacaa gaaagaattt
    33361 ccgaaaatgc ttctcaaatt tttgtggaat tttagcgtat tttacgaaat agctgctttc
    33421 tgaaactccc ttcatcgaga ggtcgtgaca tagcttttgt cacgacctct cggcttatcc
    33481 tacgagtatt attcgataca tttatatcaa taatcctttt tttattttat ctgcagcttc
    33541 ttggaacgct ccatcgtttg acacgactaa aagtgagggg atagctttca aacgtttcaa
    33601 ctgtgctaaa tcttctacat aaaccgccag tctggctgaa atctgttcag atgaatctcc
    33661 acgttttttc aggcgcgatt gcaatgtttc tttagagatc gtaataaaga taggacggac
    33721 taccgtcccg aaatactcat ataaatgcca aaaaccattt gctgtcaaaa cggcgtaaca
    33781 atttcctact gtcagtttct ttttaatttc tgctttactg gaaccatatt tatgttgagc
    33841 atattggtcc cactctgcaa actcatttcc cttgatcatc tgattgaatg tattgtcaga
    33901 aacaaaataa taatcctctt gatctttttc cccaggtctt ggtgatcgat tcgtgtaagt
    33961 aatgatcttt tgttccggct gaaaaatagc ttctgcgagt gaagtttttc cagaaccaga
    34021 aggaccgata aatacatagc aataattcat tgtcatttct cctttgatga ttgaacaagt
    34081 gaaaaagctt tggaaaatat ttccaaagct tttaaaagta actttgcttt tttgtatatt
    34141 ataccagcaa gccagtcaca atagcactta aaaagctgac taaagtcgct gttagcaaaa
    34201 ttttcaatcc gtgttttgcg acaagatttc ctttttcttc atttaatccc ttcatcgcac
    34261 cagaaatgat cccgatagaa gagaagttgg caaatgaaac gaggaagaca gatataattg
    34321 ctgttgtacg ctcagtaaaa tggaaattac catttgctaa ttctgtcata gcaacaaatt
    34381 catttgtaac cagtttagtc gccatgatac taccggcatc cactgcttct ttccatggga
    34441 ttccgctgat gaaggcaaga ggggcaaaga tgtaacctag gatctcttgg aaagtgatgc
    34501 cgaatatccc gtggaagata gcattgatca tggcaatcaa agcaacaaaa ccgataagca
    34561 tagcagcaac cgtgatcgcc acatggaaac catcaagaat gtattctccc aacatttgga
    34621 aaaatgtctg ttctttgttt tcttcaatga tcagctcatc ttctttttct tctaatacat
    34681 agggatttac aattgaagcc agaatataac cgccaaataa gttcaaaaca agggcagtga
    34741 tcacatattt agaatcgatc agtgccatat aagatccgac gatcgacata gaaactgtag
    34801 acatagccga tacactcatg gtgaacaaac gtttctcaga taggaagggt aattcctttt
    34861 ttatggaaat aaaaacttcc gattgtccta aaatagcaga agctactcca ttataagatt
    34921 ccaatttgcc caacccgttg attttactta atcctagacc aacagctttc ataaataatg
    34981 gaagaatctt gatatagcgt agaataccga taatagcaga aataaataca attggcatca
    35041 atacggaaag aaagaaaggt gcacttcctt tatttgctac accggcaaaa acaaagtcaa
    35101 caccttgccc agcaaaagca agaagatgat caaacatttt tgccaataca gaaacaaccg
    35161 ctgtaccaaa agttgtacgt aataatacga aaccaagaac aagctgtaaa acgaacatca
    35221 caattagtgg tttcaatttg attgcttttt tgttactgct gatcaaaaaa gcaagcccta
    35281 atgtgacaaa taaaccaata atacctaata aataactcaa ataatcactc ctattccaaa
    35341 ttccgtttta
//
LOCUS       DAFLWQ010000025        35125 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.026, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000025 DAFLWQ010000000
VERSION     DAFLWQ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35125
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.026"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            162..3389
                     /gene="fss3"
                     /locus_tag="L1V16_001175"
     CDS             162..3389
                     /gene="fss3"
                     /locus_tag="L1V16_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBN1275528.1"
                     /translation="MYKKQKKKLCVLTILSLAVQSIVGAIAPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCVEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIADYQKKPSFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENTANIDYRVN
                     GNQLIISPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTVKIDVE
                     MEGSLKIKKVDKESGDIIPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTATIKAGETISVTSKNTREKGQIILDKTGIETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGHETQGKAEFKRAEYTL
                     FTVKDGKAVKWTENFKPELLKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDSEKNAVITRDVAAKEQVIRFGFDFFKFAGSTTGTAETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDYTKSDYIFTITEKGQKQPIKTVTVPYGNLTNENFSVSLNR
                     LMLYDLPEEEDSLTSLATWKEGDKELTTLDSTELVDKLSYNLHEIKEDWYIVAQAIDV
                     DATKAAQEKDKKAKPVAIAETTATLANKEKTGTWEILHKLTVEQVLDKTIVLFNYVYE
                     SKEAYEAGDEPVAKDASLNNQAQTVNCMVERHVSIQTKAHLEEGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALFPDGTSKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYDKDGNINGKHNEDLKEKSQTLTPKKVPTTPSTPEQSEMPTVP
                     SGSQESSPTVKAFPQTGEKTSNVLLFIGFSLIFATAGYYFWNRRN"
     gene            3501..3815
                     /locus_tag="L1V16_001176"
     CDS             3501..3815
                     /locus_tag="L1V16_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBN1275529.1"
                     /translation="MELKFVVPDMVETFGKLTYGGEGEVLSEGYGRNTTIVGRSYHLF
                     SNKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLIAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            3828..4202
                     /locus_tag="L1V16_001177"
     CDS             3828..4202
                     /locus_tag="L1V16_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBN1275530.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQLNQGKPTNQNEGKK"
     gene            4203..4556
                     /locus_tag="L1V16_001178"
     CDS             4203..4556
                     /locus_tag="L1V16_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HBN1275531.1"
                     /translation="MKNMEINVEHILDCLDQFGKGELTEEQLTNALTYDEKMFLIMHQ
                     GLLEVGNDAKEDFDVLDWLGEEESFFMVVEVNESLCRQAESVLEEIDVEMPDAIERFL
                     KQLVETKQLPVVVND"
     gene            4625..5641
                     /locus_tag="L1V16_001179"
     CDS             4625..5641
                     /locus_tag="L1V16_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBN1275532.1"
                     /translation="MYKGHRIRAGDQHLIYHFVLGWLIFLFIGWMSVFYLQELRQFDI
                     SKVSFSTSEIGWSMKDVICLLGSLALSGSMMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQGEGFFKDLNSSWTKESISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LENKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIEEIVAENGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIQALLKSDAELFILDPKNADLADLGTIMPHVYSQK
                     EEISECVEDFYERMIARSRSMKEMPNYKTGENYAYLGLPPNFLIFDEYVAYMGANRFP
                     TSIE"
     gene            6235..8109
                     /gene="ltrA"
                     /locus_tag="L1V16_001180"
     CDS             6235..8109
                     /gene="ltrA"
                     /locus_tag="L1V16_001180"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBN1275533.1"
                     /translation="MNVETDEVQGSGKNVGKSVMEVPRLNTKIRYWEYYDLQETFDQL
                     FTQSRNGKKFYQLYELIISENNILLAYRTIKANKGSSTPGTDSFTIDNYKEMNQAEFI
                     HLILSHLENYKPKSIKRVMIPKPNGEKRPLGIPCMIDRMIQQMFKQILEPICEAKFYE
                     HSYGFRPLRSAKHALGRIMYLINISKMHYAVDIDIKGFFDNVNHRLLIKQLWNIGICD
                     KQVLAILSKSLKSPIQGEGIPSKGTIQGGIISPLLSNVVLNDLDHWVSKQWHTFETKY
                     PYTKGYNKFRALRDTNLKQGYIVRYADDFKIMTNDYPTALKWFHAVKLYLKDRLKLDI
                     SNEKSKIVNLRKCKSEFLGFAICVKQKGKKWVCNSRISNKKKDQIKEEIKQRIKDIQK
                     SPTAQNALLFNALVLGVHNYFRYATHINLDLNRMNYVLSFTTYNRLSNCSTRCYPNKA
                     SPTYKKFYSTTMKTYKVAGVYLYPLCDVSTKTIYGFNTEDTPFTPFGRQRLEHKSLQS
                     LVFQELRKLMESKIPNRTVEYLDSRISRYSMKSGKCEITKQFLPAKAVHCHHYLPKSL
                     GGDDKFDNLRIIHKDIHLLIHTTNKMIIDHYVHELKLVPEQIAKINLYRKMCNLQNIQ
                     "
     gene            8235..8591
                     /locus_tag="L1V16_001181"
     CDS             8235..8591
                     /locus_tag="L1V16_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HBN1275534.1"
                     /translation="MILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRV
                     ALGRMSELGYSMMFGEVDKNFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREIS
                     NIVGLTVHTERENNSV"
     gene            8636..9778
                     /gene="dcm"
                     /locus_tag="L1V16_001182"
     CDS             8636..9778
                     /gene="dcm"
                     /locus_tag="L1V16_001182"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HBN1275535.1"
                     /translation="MTFLDLFAGIGGFRLGMEQAGHQCIGFCEIDEFARRSYKAIHDT
                     RKEVEMHDITSVSDEFVRSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     ATLLQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQSRERI
                     FLIGHSRDACTEQVFPIIGSSSTSDQNIRNLVNINPSNRGMGGQVYGSDSVAPTLTGD
                     EGIKIALPVKDGISVAGMLSGNFEQGNRIYEVTGTAPTLSTKQGGTKIMIRKNETEYQ
                     EVKPGDSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKGVKAYDL"
     gene            9768..10057
                     /locus_tag="L1V16_001183"
                     /pseudo
     CDS             9768..10057
                     /locus_tag="L1V16_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            10313..11497
                     /locus_tag="L1V16_001184"
     CDS             10313..11497
                     /locus_tag="L1V16_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBN1275536.1"
                     /translation="MAQRNLDYRLLKERRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     IASTKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDVRKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYYAIQDLL
                     KGRSIESTTFSIINRYLRFADKVDGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     IV"
     gene            11494..11607
                     /locus_tag="L1V16_001185"
     CDS             11494..11607
                     /locus_tag="L1V16_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBN1275537.1"
                     /translation="MKRGILMEIVKDMLLVLGGSMLGVTVMCLMNASAAAD"
     gene            12377..14287
                     /gene="ltrA"
                     /locus_tag="L1V16_001186"
     CDS             12377..14287
                     /gene="ltrA"
                     /locus_tag="L1V16_001186"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBN1275538.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            14391..14615
                     /locus_tag="L1V16_001187"
     CDS             14391..14615
                     /locus_tag="L1V16_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275539.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLNLFNRIVGA"
     gene            14628..15131
                     /locus_tag="L1V16_001188"
     CDS             14628..15131
                     /locus_tag="L1V16_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBN1275540.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKEQIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCNLAEELEGTPIGEAASEIQHAFFNSFEEMVEH
                     VDDIVYYPDCDDMSDVAHYLIVEAGDFGEVPEQLKPYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPE"
     gene            15258..16295
                     /locus_tag="L1V16_001189"
     CDS             15258..16295
                     /locus_tag="L1V16_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275541.1"
                     /translation="MANIQTSFIDFHNSIRLDVEDNTLLKDYKDQVIDGLKDYLPDDV
                     KFETFLQGSYSVYTGIKSCDEKIDFDIDIAVAFEIDHTVYEDPREPKLWVKEALVEIF
                     PNAQVNLKVPCVTATFTGKKTKKNVHVDVAVYAKEDENYFLAKAKEFSAPENRCWEEA
                     DPKVLKEKINSHVADSDDRKQFRRCIRYLKRWKDNNFNQEYKPTGIGLTINVMDTFLV
                     NKSTDFLTRKVQYNDMECMKQIVSSLKDSFVYEYSETDGWHYRLHAYLPVKPNSDTYS
                     KMTVNQMSDFKNKLSKLYDDLIFAIDTEDEYEATKRLNNQFGEDFLIISEEEVTEKNL
                     RNAFVTDYPSA"
     gene            16310..18007
                     /locus_tag="L1V16_001190"
     CDS             16310..18007
                     /locus_tag="L1V16_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HBN1275542.1"
                     /translation="MDYTDILKEKLTDVVRLFDGNYYGDFSFATIGKLRLKIEIPKHF
                     PLVLPRIYIHNFDHLGLYLPHVEKDGLVCFSSDINYLVDEENSELVLLQCVNKTIKTI
                     EEGLKGLNKNDFRKEFVAFWDKQENQISLFYLCEPALFIKSVDTIMYGKSLVALDKEN
                     ELQLNAASRLFNGEKEDTHELDAYYVPIRNKNNIMPPKNNKAWSKKDILQIVKKNVTG
                     ANKRFFLKLEKRKNRHNVLLILDIPIEEKSNNVIIGFLFTKQSGSIKDYKGTPRTVLV
                     QRHDELYLVNRTSGENYGLGANIAIVGVGSVGSKIAENLGPLGVRKMTLIDNDCFQAE
                     NLYRNSLGADSLKNARSQNNFFKVDLMQEELEKKIPYLCVEVESMNVLDLISMQPGFF
                     KEYDYVFVCIGDTMASLALNNYFSKSSQKVFYSWLEPYGIGGHTLFINYSLNQKGCFN
                     CLYTDSNSKNRCSNRASLVKEGQIFERTLASCRSKFIPYNAIASTECAINAIKLFHKV
                     NQNNMTNSTLFSWIGDGSTFENLGYQYSDRNTFLNGVNKFEERFFSKYCKVCGELDD"
     gene            18000..18461
                     /locus_tag="L1V16_001191"
     CDS             18000..18461
                     /locus_tag="L1V16_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mov34/MPN/PAD-1 family protein"
                     /protein_id="HBN1275543.1"
                     /translation="MIKFSCDRIVIEVRDEVLKIFEQYRQGKDDLPEAGGVLHGKRLK
                     NGSIIITDITTPQIGDIQKRLLFKKNREIHQQLSNEKWIESNKFSIALGEWHTHPEAV
                     PTPSNVDKKSWRLNVSKQHDDRVYVFIIVGFSDLRMWLLSKKSDIRQAIKL"
     gene            18474..19334
                     /locus_tag="L1V16_001192"
     CDS             18474..19334
                     /locus_tag="L1V16_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275544.1"
                     /translation="MKSQKNIWWWGFLVGKVMIPALLLISLPMITFFFTNKKMSKEAV
                     IFFFGDQKATFIETLVTSLQLNLNYIFSIIIVISLLNFFKKRNSGKVFNSNGNVYYNY
                     FYFVFWVAATLLGYDKIQIAGIPIHMQYKLVLSGIFSEVLPDIYDDHYDSDGTCKVSI
                     EKENFDDIDGYDSVNLLIIDTYDIKMSELSMENQTYPTIIVRGNSIDGVRKVNRSLIL
                     EIKKTMDEIQKSDFKKVFVASTSNPKNSINIINSSFRFFGRSRRFKLYVLQKDYASNG
                     KYSKKYRIFI"
     gene            19372..19761
                     /locus_tag="L1V16_001193"
     CDS             19372..19761
                     /locus_tag="L1V16_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBN1275545.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLMFV
                     IVFAHVPPLSMIEGAFLKYLGIPIAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            19745..22195
                     /locus_tag="L1V16_001194"
     CDS             19745..22195
                     /locus_tag="L1V16_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1275546.1"
                     /translation="MMYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKYQVHD
                     NFRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDLQTDALVSM
                     IGDSQIDYRFFIGFKLISTDEEVNLKNLRKSFFSGLQEFVYGVNHHLMGDFVSLSNEE
                     IRRYTKLEKLMESKLARRFKVKRVTPSDLTYLIEHIYGEKGTPFEEYEFQLPKKKLKS
                     ETLVKRYDLLRPTRCLIEEKPRYLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQ
                     QQQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSV
                     DELETTLDQSKESMYKLSYVVRVSAKSVDELKRRCDEVLDFYDDTNVKLVRPFGDMMG
                     LHKEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKP
                     ALASQGVKGSVTNALASAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWK
                     ETLPEIADEINILNLTSKPENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEK
                     FPVLRKAIRTVTQSDQRGLLQVIVELRKEDSPVAENIADHIESFTDYDFAHLLFSDGS
                     ITQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNRE
                     IFKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGL
                     KFAFRSTDIHEIKKTLEFFGLDKEDESNQKCMRDLENGQCLMQDLYGRVGVVQVHPVF
                     EELFHAFDTRPPVQERME"
     gene            22200..24308
                     /locus_tag="L1V16_001195"
     CDS             22200..24308
                     /locus_tag="L1V16_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBN1275547.1"
                     /translation="MKKKLFRIFGIVLISLVTLIILLSLVGTVAEATGLVDDTVGAGN
                     LYSQYSLGNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEVGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMNMFNLQSNDSQSMGRRVMRKPQMLMNRTLR
                     QLNRNVGRTLAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEIPSDLNKEK
                     PIPNNKKQSRMNLAGRKVGKVLDTQALVKDKTKQVKDGVRNTPTNLKYNFHKGIEKTK
                     KAPEEFKRGLVQEKANRGELREKQQQRRDEKIAEKRKVLNEIGNPHGKRRENVPIKAK
                     VQSQKDRAPKRIVRANSNPEIKRKFASQEIISKGINQSSSKKNSFQQVKRRSTLSKRT
                     NRKVQKSLNPHPKPRSGEKK"
     gene            24305..25309
                     /locus_tag="L1V16_001196"
     CDS             24305..25309
                     /locus_tag="L1V16_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBN1275548.1"
                     /translation="MNVKKLSAISLTFLTISFMGILMCVGLLFGEDSEGSSSSGAPPG
                     GSSVSEEVLKHRAMVEKYAKESDITEYVPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNFGGGYLDYVAKNGKKHSFALA
                     ESFSKEKSCGQKIDYPNPIANKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSRPETGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTESYWQQHLIGAGRYK
                     "
     gene            25328..26239
                     /locus_tag="L1V16_001197"
     CDS             25328..26239
                     /locus_tag="L1V16_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBN1275549.1"
                     /translation="MKIKIERNQKEKSLKKKKERVVSVGKHRKMVLALWLLLSCSLTF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGIENFTKDFSKEYFSWKNNKEAIEKRMNNL
                     EQYLTEEGFALSQDMVRADIPTNSEVQSVKVLDVEKSSEEFVVSFLVEQKITEGKKAQ
                     SISSAYRVTIFEDENRNYIVTSLPTMIAKPDRAKYKTKQVENDSKIDAKTTEEIAEFL
                     ETFFKLYPSASEKELEYYVENDAMRPINIDLKFSKLEDPVYLQNGKKILVSTKIKYLD
                     NVSKTTSYFQYKLILQKNGNWKIIDVK"
     gene            26426..26713
                     /locus_tag="L1V16_001198"
                     /pseudo
     CDS             26426..26713
                     /locus_tag="L1V16_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(26901..27116)
                     /locus_tag="L1V16_001199"
     CDS             complement(26901..27116)
                     /locus_tag="L1V16_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275550.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(27375..27542)
                     /locus_tag="L1V16_001200"
     CDS             complement(27375..27542)
                     /locus_tag="L1V16_001200"
                     /inference="COORDINATES: protein motif:HMM:NF018933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1275551.1"
                     /translation="MGSECGHTDGKKSFTIREWTCPICRTHHDRNVNVSINILIKGYV
                     YKHCLRKHQEP"
     gene            complement(27887..29326)
                     /locus_tag="L1V16_001201"
                     /pseudo
     CDS             complement(27887..29326)
                     /locus_tag="L1V16_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(29874..30545)
                     /locus_tag="L1V16_001202"
     CDS             complement(29874..30545)
                     /locus_tag="L1V16_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HBN1275552.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRYLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCQCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEKWIAYITLK
                     KRGTI"
     gene            complement(30894..32345)
                     /locus_tag="L1V16_001203"
     CDS             complement(30894..32345)
                     /locus_tag="L1V16_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBN1275553.1"
                     /translation="MKKSLKLASAVILMSQLFIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTLSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSAESSTTSSSTSEITSSKVTRPNHIESSKKEAPKTEGQTKNFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            complement(32457..33800)
                     /locus_tag="L1V16_001204"
     CDS             complement(32457..33800)
                     /locus_tag="L1V16_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBN1275554.1"
                     /translation="MKKIVIIGSNHSGLAAARFLNLCDSNYEVILIDKKSEISYLECG
                     TSLFIKREVSNLEDLFYQNRRELNSKIKKLFLETAVDKIDIQNKKIICVKKDGTRFSQ
                     EYDKLILATGSKQIMLDVPGNNLANIFSIKNFPNAKEIFKALDDNTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGKKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHIDNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPVFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            complement(33934..>35125)
                     /locus_tag="L1V16_001205"
     CDS             complement(33934..>35125)
                     /locus_tag="L1V16_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1275555.1"
                     /translation="SDADKYNPEGQKVTTELNKEPDASEGIKNKEDLPKDTKYTWKEK
                     VDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEGEKVEVGGTVDL
                     TDNVTNLPTLPEGTTVTDVTPDGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDN
                     RSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGIV
                     VVTYPDGSKEEVEVTISVEDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPNGSQ
                     YHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNEKDSEKAVSKDN
                     KTDNQGSKQNKNRGKSSPQKQSSKAYPKTGEIDSNIFTISGGLILLGTLGLLGYKNRK
                     KENE"
BASE COUNT        11607 a         5964 c         6987 g        10567 t
ORIGIN      
        1 tttaaaggca gtatatttcg tattttatat taaattttta ggctcattca ttctcaaatc
       61 cattctattt agtcaataaa tattttaaaa agactttata aacaaagatg ttcaagcgag
      121 catcttattt ttttgtgcct aatttgaaag gagaacattt catgtataaa aaacaaaaaa
      181 agaaattatg tgtattaact attttgagtt tggctgttca atcaattgta ggagcaattg
      241 ctcctacgat tgcttttgct gatgaaatta cccatccaca aacggtaacc gtagaactag
      301 atttagcaca tcaatatgct gttgaaggaa cttttagtga tggtcgtcca atgtcagaag
      361 tcactgttcc gcattatgca gtgtacaacg gcgttaaaca agatattttc tgtgttgaac
      421 caggagtccc gatttacaat gagttcactc ctggatatga gaagaacccg ttaccagata
      481 tgtccgataa agccaaatta gtttccgttt tatggaaaaa agtaggtaca gatgcagata
      541 ctcatattgt ggcacagaag atgatctggc aagaagttaa tgggtatacc cttcactcaa
      601 taaaacgatc agatggtagt gccgtaaata tcgcagccat tgaggcaaaa atcaatcaag
      661 ccattgccga ttatcagaag aaaccaagct tccataatag tacggctaaa acagtattag
      721 ggcaatcgac tactgtgacg gatacgaata atctgaattt gtcagagttc gatgaggttg
      781 tggaaaatac cgcaaacatt gattatcgtg tgaatggcaa tcagttgata atcagcccaa
      841 atgccaattc aaaagaaagt ggtgtgttga cgcttaagaa atctgctggt accggaacac
      901 ctgtcgccta taaaaaggct ggccaacaga ctttaatggc cggggcgatc gataagccga
      961 acacttatac ggtcaaaatt gatgtggaaa tggagggttc tttgaagatt aaaaaagttg
     1021 ataaagaatc gggtgatatt ataccaggaa cggttttcca tttagacttt ggaaaaactt
     1081 tacccgcaaa agacgtgacc accgataaag aaggcattgc gaccttagat gagattcctc
     1141 atggtacaaa ggtaaccatt actgaaaaat cggtgccggc gccttatacg attgatacca
     1201 cacccatgac tgccacaatt aaagcaggtg aaaccatttc agtgacttca aaaaatacgc
     1261 gagaaaaagg tcaaattatt ctggataaaa ccggaattga aacagggagt gatctttgga
     1321 acgataatta ctctttagcg ggcaatacgt ttgccattcg caaggatagc ccaactggtg
     1381 aaatcgtcca agaaatgacc acggatgaaa aaggtcatgc agaaacacca aaagagattg
     1441 ccaatgcgtt ggaattggga acctactatg tgactgaaac caaggctagt catggctttg
     1501 tgaatacttt caaaccagta aaagtcgaat tgaattatgt caatcaaaca gtggctcttg
     1561 ttaccagtaa cgtaaaaggg caaaaccaag aaattactgg tgaaaccact ttgacaaaag
     1621 aagacaaaga taccggtcat gaaactcaag ggaaagctga gtttaaaaga gctgaataca
     1681 ccttgtttac tgttaaggat ggaaaagcgg tcaaatggac cgagaacttt aaaccagaat
     1741 tgttgaaggg aacgaaagct tctgatgaaa ccgtaacttt gactttagat gaaaagaatc
     1801 aagttgccgt taaacactta gcgattaatg agtattactg gcaagaaacc aaagcgcctg
     1861 aaggatatac cttggatgaa acaaagtatc ctgtatccat caaaaaggtg gatgatagcg
     1921 aaaaaaatgc tgtgattact cgagatgttg cggcaaaaga acaagtgatt cgctttggct
     1981 ttgatttctt taaatttgct ggatcaacta ctggcactgc cgaaactggc ttcaatgatc
     2041 taacctttaa agtgtcgcca ttggaaggaa ccaatgaaat caccggtgcc gaagatgaag
     2101 cgaccacagc ttataacgag caattagggt ttgatggtta tggcaagttt gaaaatcttc
     2161 cttatgggga ttatttactt gaagaagtag aagccccaga aggttttcaa aagattacgc
     2221 cattagaaat ccgttctact tttaaagaaa ataaagagga ttataccaag agtgattata
     2281 tctttactat taccgaaaaa gggcaaaagc aaccgattaa aacggtaacg gtcccttatg
     2341 ggaatctaac caatgagaat ttctcagtca gtttgaaccg tttgatgctt tatgatttgc
     2401 ctgaggaaga agatagctta acttctcttg cgacttggaa agaaggagat aaagaattga
     2461 ctactcttga ttctaccgag ctagtcgata aattgagcta taatctacat gaaatcaaag
     2521 aagactggta tatcgtagct caagccatcg atgtagatgc tacaaaagct gcccaagaaa
     2581 aagataaaaa agccaaaccg gtggcgattg cggaaacaac cgcaacttta gcgaataaag
     2641 agaaaacagg aacttgggag attctgcata aattaactgt cgaacaagtt ttagacaaga
     2701 ccattgtctt attcaactat gtgtatgaaa gcaaagaagc ctatgaagct ggtgatgagc
     2761 cggtagcgaa ggatgctagc ttgaacaatc aagcgcaaac tgttaattgt atggtggaac
     2821 gtcatgtttc catccaaacc aaagcgcact tagaagaagg ttctcagacc tttactcatg
     2881 gtgacgtggt agatatgttt gatgatgtat ccattaccca tgatgtacta gatggctcaa
     2941 aagaagcttt tgaaacaatt ctgtacgctt tatttccaga tggtacaagt aaagaaattt
     3001 ggaaatctgg caagattgat tacgaagtga atgacaaaga atttaccaaa accgtacttg
     3061 cggaaaaagt ggatacaagt aaatatccag aaggtacaag ttttaccttc aaagaaatta
     3121 actatgacaa agatgggaat atcaatggaa aacacaatga agatttgaaa gaaaaatctc
     3181 aaactttaac gcccaaaaaa gttccgacaa caccaagtac accagaacaa tctgaaatgc
     3241 caactgttcc aagtggctct caagaatcta gtcctacagt gaaggcattc cctcaaaccg
     3301 gggagaaaac ttccaatgtg ctactgttca ttggctttag cttgatcttt gcgacggctg
     3361 gctattattt ttggaatcgt cggaactaag gtgataagat gaaacatgta aatagtagaa
     3421 aacaatacgc gcgaccgcct cctaaaaaag tggtcgcgct atttttgtat tcaaaactaa
     3481 caatgaaaag aggaaaaaat atggaattga aatttgttgt accagatatg gtcgagacgt
     3541 tcggaaaact aacatacggt ggtgaaggtg aagttctatc ggaagggtat ggtcgaaata
     3601 ctacaattgt tggtcgaagt taccatctgt tttcaaataa acaacgggcc gatgatattg
     3661 aagtggtggt agctgcggaa gccggcgaaa aggattttga ccaagatcaa ccactaaaag
     3721 ctgtaaatcc ccacttaatt gccaaaggct atgaaattga gaatcgtggg tttaccgatt
     3781 acgtgttgta tgttgatgat ttagtgaaag cataggagga aaagaagatg agattaacag
     3841 aaggtattgt cgtagattca ggattaacct ttggcaagtt gcgtttttcc gcattacgtc
     3901 gagaagtacg caagcaaaat gaggacggaa cggttagtaa cgaggtaaaa gaacggacct
     3961 ataatttgaa atcctccgcg caaggtcgaa tgatccaagt cagtattcca gcaaatgtac
     4021 ccttacgcga gtttgcttat gatgcagagg tagagctggt caatccaatc gtggatacgg
     4081 tcgccaatta tgtttttcgg gaaggaacca ccgttaattg gtttatcaag gcagatgatt
     4141 tagtcttgaa acgacaactg aatcaaggaa aacctacgaa ccaaaatgaa ggaaagaaat
     4201 aggtgaagaa tatggaaatt aatgttgaac atattttaga ttgtctcgat caatttggca
     4261 aaggtgagct aacggaggaa caactcacta acgcattaac ctatgatgaa aaaatgtttc
     4321 tgattatgca tcaagggtta ctggaagtag gtaacgatgc caaagaagac tttgatgtac
     4381 tggattggtt aggggaagaa gagtctttct ttatggttgt cgaggtaaat gaaagtttat
     4441 gtcggcaggc agaatctgtt ttggaagaaa tcgatgtgga gatgccggat gccatcgaaa
     4501 gatttttaaa acaattagtg gaaacgaaac aacttcccgt agtagtaaat gactagcata
     4561 actttttgaa attgcccaat gaaatcctat tgggcttttt cgactggagg tggaaaccat
     4621 caaaatgtac aaaggacatc gcatacgcgc aggagatcaa cacttgattt atcactttgt
     4681 tcttggctgg ctaatctttt tgttcattgg ttggatgagc gtcttttatt tacaagaact
     4741 tagacaattt gatatttcta aggtatcatt ttccactagt gaaattggct ggtctatgaa
     4801 ggatgtaatc tgcttgctag gaagtctcgc tctttcagga agcatgatgt tactttatat
     4861 acactttttt caggatcatt ggcgaagtct ttggcatcga caaaagttag ctcggatgat
     4921 tctagaaaac cattggtatg aagtaaagca gactcaaggt gaaggttttt tcaaagattt
     4981 gaatagtagt tggaccaaag agagtatcag ttacttcccc aaaatttatt atcgaatgaa
     5041 agatggctta ctttctattc gcgttcaaat ttcactggga aaatatcagg atcagctatt
     5101 gaagttggaa aataagttag aaagcggact gtattgtgag ttagtagaaa aagaactcaa
     5161 agactcctat gtggaataca ccttgttata cgatatgatt gccaatcgaa ttgggataga
     5221 agaaatagtg gcagaaaatg gggcgttgcg attgatgaaa aatcaagtat gggcgtatga
     5281 ttccttgccg catatgttaa ttgctggcgg cacaggtggt gggaagacct atttcttact
     5341 caccattatt caagcactat tgaagtcaga tgcagaattg tttatcctcg atcccaaaaa
     5401 tgcggacctc gccgatttag gtacgataat gcctcacgta tactcccaaa aagaagaaat
     5461 ttctgaatgt gtggaagatt tttacgaacg catgatagct cgtagtaggt caatgaaaga
     5521 aatgcccaac tacaaaacag gagagaatta tgcgtatctc ggacttccgc ccaacttttt
     5581 aatctttgat gaatacgtgg cttatatggg tgcgaatcgt tttcctacaa gcatcgaata
     5641 gatgtgaaat ggaagcctat tgagattatc aatagtgaca actaatgttt tgagagatgg
     5701 aatgaaagcc ttcaagttga gctgaaacat ccccgctaat actcctacat gctctaatca
     5761 atgaagtaga ttggttttgg tatgaagcta ggtgaagtcg tctgaaatct gcctaagtgc
     5821 ttgagcataa ggctgactat agggcgggcg gctgaaaaag ataactatgg taagaatgtc
     5881 tgaaaatgac tgacgaatct gcgaatgtac gggtctaaaa ggctgatctt attgaaagat
     5941 aggaacatac ggacgtatgg tgagataccg acaagtaagg ttccatgata tgaaaatcgg
     6001 gatagctaac gaagaagcta taatttcaca ggctcatagt agatacctaa ggttatacat
     6061 gatagctaaa aacattggaa cgatgtaagc agaaaactat caattaaatg actacttcta
     6121 gataggtgca tataagtaat aacgaaattg ctttgtttct gtgaaagtaa gggcacagta
     6181 ccgatgaagc gtctaacaaa tgtggaggga tagccctaag tctatttaat aacaatgaat
     6241 gttgaaacag atgaagttca aggatctggt aagaacgtgg gaaaatccgt tatggaggtg
     6301 ccacgcttga acacaaaaat acgttactgg gaatattatg atctacaaga aacattcgat
     6361 cagctattta ctcaaagtag aaacgggaaa aagttttatc aattatatga gttaatcatt
     6421 tctgaaaata atattctttt agcataccgt actatcaagg caaacaaggg gtcttcgaca
     6481 ccaggaacgg attccttcac aattgataac tataaggaaa tgaaccaagc agagtttatc
     6541 catcttattc tcagtcattt agaaaattac aaaccaaaat ccataaagcg agtaatgata
     6601 cctaaaccca atggtgagaa acgcccatta ggaattccat gcatgattga tcgaatgatc
     6661 caacagatgt tcaagcagat actggagcca atatgtgaag ctaagtttta tgaacatagc
     6721 tacggtttca gaccattgag aagtgcaaag catgctctag gtcgcattat gtatctcata
     6781 aacatcagta aaatgcacta tgcagtagac attgatatca aaggtttctt tgataatgta
     6841 aaccaccgtt tactgataaa acaattatgg aatataggaa tttgtgacaa acaagtctta
     6901 gctattcttt caaaatctct gaaatcaccc attcaaggag aaggtatccc gagcaaagga
     6961 acgatccaag gaggtatcat ttctccacta ttatctaatg ttgttctaaa cgacttagac
     7021 cattgggtct caaagcagtg gcataccttt gaaacaaagt atccctatac taaaggttac
     7081 aataaatttc gtgctctaag agatacaaat ctaaagcaag gctatattgt caggtacgca
     7141 gatgacttta aaatcatgac taatgattat ccgacagcat taaaatggtt ccacgctgtc
     7201 aagctttacc taaaagacag acttaaatta gatatttcca atgagaagtc taaaatcgtc
     7261 aatttgcgta aatgtaagtc ggaattttta ggattcgcta tttgcgtgaa acaaaaaggg
     7321 aaaaaatggg tttgtaattc acgtatttct aacaaaaaaa aggatcagat taaagaagag
     7381 attaaacaaa gaatcaaaga tattcaaaag agtcctacag cacaaaatgc tctcctgttt
     7441 aatgctctcg tgctcggtgt tcataattat ttcaggtatg ccactcatat taatttagat
     7501 ttgaatagga tgaactacgt tctttcattc actacttaca accgattatc aaattgtagt
     7561 acaagatgtt accccaacaa agcttcccca acttacaaaa agttttactc aacaacgatg
     7621 aaaacgtata aagtagctgg agtctatttg taccctcttt gcgacgtatc tacaaaaaca
     7681 atttacggat ttaatacgga ggatacaccg tttactccgt ttggtcgtca aagattggag
     7741 cacaaaagcc tacagtctct tgtgttccaa gaattaagaa aattgatgga atcgaaaata
     7801 ccgaatagaa cggttgagta tttagatagt agaatatctc gttactcaat gaaatcaggc
     7861 aagtgtgaga ttacaaaaca atttttgcca gcaaaagccg ttcactgtca tcactatttg
     7921 ccaaaaagtc ttggtggaga cgacaaattc gataacttga gaattattca taaggatatc
     7981 catcttctga tccatacaac aaataaaatg ataatcgatc actacgtgca tgaactgaaa
     8041 ctggtgccag agcaaatagc aaaaatcaac ctttatcgaa agatgtgtaa tctgcaaaac
     8101 attcaataga aaataaatag atggaacgcc gtatgaggtg aaagtctcac gtacggtgtg
     8161 gagcggggga aaagatggag attatatcaa attcttacct atcgctatag atgttaacga
     8221 caaaagaaag tgcggtgatt ttgaataagc ttaaacaaat cgtgatgtta ggccgtcaat
     8281 ctggtttctt tctgattcta gcttgtcaaa ggccggatgc gaaatatcta ggagatggga
     8341 ttcgcgatca gtttaacttc cgtgtggctt tgggtcgtat gagtgagctt gggtattcca
     8401 tgatgtttgg agaagtcgat aaaaattttt ttatgaaacg catcaaagga cgaggttatg
     8461 tagatacagg gggcagtgtg attagtgagt tttatacgcc acttgtacca aaagggtatg
     8521 atttcttaag ggaaattagc aacattgttg gattaaccgt tcatacggaa agagaaaata
     8581 atagtgtgta gcctaggaat atcaataatc ctgggctttt ttattgaggt gatttatgac
     8641 atttttagat ttattcgccg ggattggtgg ctttcgctta ggtatggaac aagccggtca
     8701 ccagtgtatc ggtttttgtg aaattgatga atttgctcgg aggagttata aagcaatcca
     8761 tgatacaagg aaggaggtgg aaatgcatga catcacaagt gtatcagacg aatttgttcg
     8821 atccctcgga ccagtggaca tcctttgcgg cggctttccg tgccaagctt tttcaattgc
     8881 gggaaagcgg caaggatttt ccgatactcg aggtacttta ttctttgaaa tcgctcggtt
     8941 cgccactctt ctccaaccta agtttctatt ccttgagaac gtccggggat tgctcaatca
     9001 cgaaggaggg gctacgttcg agacgatcct ccgaacgttg gatggattgg ggtatgatgt
     9061 ggaatggcaa gtgcttaact caaaggccta cgttccccaa agccgtgagc ggatcttcct
     9121 tatcggacat tctcgagatg catgtaccga acaagtattt cctatcattg gatcgtcttc
     9181 aacatctgat caaaacatca gaaacttggt aaatatcaat ccttccaatc gaggaatggg
     9241 tggccaagtc tatggttcag atagcgtagc accaaccttg accggtgatg aaggaattaa
     9301 aattgcctta ccggtaaagg atgggatttc tgtagcgggt atgttgtcgg gaaattttga
     9361 acaaggcaat aggatttatg aggtaaccgg aacagccccc actttgtcaa cgaaacaagg
     9421 gggaacgaag attatgattc ggaaaaatga aacagaatat caagaggtga agccagggga
     9481 cagtgtgaac ctggcttttc ctaattccac aagtcgccga ggtcgtctgg gaaaacaaag
     9541 tgtgcatacc ttactaacag gagaccaaca agcggtagtc acggatcagt accagattcg
     9601 aaagttaaca cctagggagt gctggcggct tcagggcttt ccagattggg cttttgatcg
     9661 agcttctcaa gtcaattcag atagtcagtt gtataaacag gccggaaact cagtaacagt
     9721 tccggtcatt tttgatattg ctagaagatt aaagggggta aaagcatatg atttatgacg
     9781 agttgattgg agaaatctac tggatgattg gcaagattca ggcagatccg aaattggaag
     9841 aagaactgta ccggctcaat tttgatattc gcaaaaacgg ggtgaaagtc caggtgattc
     9901 gtatgtagtg gatgaggaaa cggatgctcg aatggagctc aatcaagtca tcggtgaatt
     9961 ggaacgaatt gcggaccttg ccaaagaacc tgatatccgc caatacttgt ttgagataaa
    10021 agcagagttg gaaattgagg gtatcaccgc ggagtaatag ggaaataacc cactgatagg
    10081 cactgaccgc gggggatttg cgaagcagaa atcctccgtg gtgctgtgcc tgttcatgga
    10141 cggcggcagc cggccatgat gtctcacccc ccgtatctaa caggggggta caaaaacaca
    10201 aaaaacaagc aagtaaccat aaaaaatgct tgttgtatca aggatattaa gtaatttgta
    10261 taggtgttaa ctcatttgga aaagttaaca ccttgaattt ggaggtgaaa acttggcgca
    10321 acgaaattta gattatcggt tattaaaaga acgacgcaac gaatatggcg tttcacaaaa
    10381 taaattagct actgcttgcg gacttagccg cccataccta aatcagatag aaaacggtgg
    10441 cgtaatcgcc tctacaaaga ccatgagaaa aatttttgat caactggaaa gtttcaatcc
    10501 cgatttacct ttaacgttac tatttgacta tgtaaggatt cgctttccca caacggatgt
    10561 gcggaaaatt attcaagaaa ttctccattt gaaattcgag tatatgcttc atgaagatta
    10621 cgccttttac tcctatcaag aacaatatgt catgggcgat attgtagtga tgttatctca
    10681 tgaagaagat aaaggtgtcc ttttggaatt aaaaggtcgt ggttgccggc agtttgaaac
    10741 ttttttactc gcccaaaagc gtagctggta cgactttttt gaagattgtc taaaagccgg
    10801 tggcgtgatg aaacgcttgg atttagcaat caatgatcga gtggggctac tggatattcc
    10861 tgatttaacg aaaaaatgtc agaaggaaga atgtatctcc ttgtttcgta ccttcaaaag
    10921 ttaccgttcc ggggaactgt tgaaagctga tgaaaaggat ggtatgggca ataccttata
    10981 tattggcagc ctcaaaagcg aggtttattt ttgtttgtac gaaaaagatt atgaacaata
    11041 tatcaagtta gggattccat tggaccagac cgaaacgaaa aatcgttttg agattcggtt
    11101 gaaaaatgac cgtgcttatt atgcgattca agatttgtta aaaggtcgta gcattgaaag
    11161 taccacgttt tccattatca atcggtattt gcgatttgcg gataaagtag atggaaaacg
    11221 gcgaaccaat tggcccttga atgaacaatg gggtcgtttt attggacgga atcggaaaga
    11281 gattcaatta acttctgaac cgaaaccgta taccattgaa cgaacattaa attggctagg
    11341 tagacaagtc gcccctacgt ggaaaatggc taaggagttg gatcgattga atcaaacaac
    11401 gtatatccag gatatggtac agaatgcgcg actctcggac cggcataaaa agattttgga
    11461 gcaacaaagt atggcaatcg aaaacttgat tgtatgaaaa gaggaatttt gatggaaatt
    11521 gtaaaagata tgttattggt acttggtggc agtatgcttg gtgttaccgt gatgtgcttg
    11581 atgaatgcaa gtgcagcagc ggattgagca atggaaaaga aaggaaagtg acaaaatgaa
    11641 tttcggacaa aatttatgtg cgactcgttc cttagtgaaa agctaaggca ctaataaaag
    11701 aacgaaaaag tttggttatt aggagaactg ataatctgac aggtggaatg atgaagtaac
    11761 gctctgaaac gcctgccctg agcctccgac aagcattgta tgaggaaact cagaatgttt
    11821 gaagctcggt aaagacggct gaaagatacc gtaatagttg atgaacatat atcttctatc
    11881 gaaaactatc cagaggtggg tagcgtatcc aacaggtcgg gggtctataa aatatctatg
    11941 gttagaatgt tctataagga actgacgaaa cagcgaatgt acgggtctaa atttgaactt
    12001 tgtagaaatg caaaggtacg agaaatcgta gctggtgtgg caaagtaaga atataggtta
    12061 tgaaatgcca tataacgtta caggcggtat caagccagca ggcttatagc tagtgaccta
    12121 aggatatata tgtatagata agattatcgg aacgaggaaa ggtattgggt tctcatcaag
    12181 agaataaact gacgaagaac aataagcagt tgaactaatg ctgaaaagca gagggcgaac
    12241 ctaagaaatt cttgtaatga gaatggagga atgccctcaa gtcgtgtata tattagaaaa
    12301 gtattatgtt gtttcaataa ggattacgag taagataaaa aagctcactc aatttcaagt
    12361 aaaggagtga agccttatgc ctaaaaataa aaatgaaaca ttgtgtgtag aagatttaag
    12421 acacgctgaa tattacgaaa tgcaaaacac ctttgatgat ttatatgcca aaagtaagaa
    12481 tggagatatt ttcactcatc ttatggatat tatcctatcg agagaaaata tattactggc
    12541 atatcgaaat atcaaagcaa atgcaggcag taaaacagca ggaacagacg gtacaataat
    12601 taaagatatt ggcaaattgc cagcagaaac agttgtcaaa aaagtaagat acattgttgc
    12661 aggcagtcca catgggtatc gacctaagcc agtgaggcga aaagaaatac caaaaccaaa
    12721 tggtaaaacc agacctctag gtattccttg tatgtgggac aggcttatac aacaatgtat
    12781 aaaacaagta ttagaaccaa tctgcgaagc taaatttagt gaaaacagct atggttttag
    12841 acctaatagg tcagttgaaa atgcaataaa agcaacctat aaccgcctac aaatcagcca
    12901 gctacattat gtgattgaat ttgatattaa gggtttcttt gacaacgtga accattccaa
    12961 gctgataaaa cagatatggg ctatgggaat acgggacaag cacttgatat tcattttaaa
    13021 aaggatatta aaagctccaa tcaaaatgac taacggtaca ataacatatc cagagaaagg
    13081 aactccgcaa gggggaataa tatccccact actagcaaac attgttctta atgagttaga
    13141 ccattgggta gaaagccaat ggcaggaaaa tcctgttaca aaaaactatg tggttcatat
    13201 caataaaagc ggtagcccat gtaaaagcaa cgcttacaaa gaaatgaaga aaacaaagtt
    13261 aaaggaaatg tatatggttc gttatgcaga tgattttaga gttttctgcc gctacaagga
    13321 aagtgctgaa aaagccaaaa tagcaatcac tcaatggatt gaacaacgat taaaattgga
    13381 agtatcacaa gaaaaaacaa gaattgtaaa tgttagaaaa agatactccg actttcttgg
    13441 tttcaagatt aaaatgatac cgagaagaaa gaagttagtt gttaaatcac atataagtga
    13501 taaacaattc aaaaaccaaa aagacaagct ggtatcacag gcaaagaaaa ttgcttctcc
    13561 ctcaaaaggg aaaacggaat tagaagaaac aagactttat aattcaatgg tattaggtat
    13621 gcaaaattat tatcagattg caacgaatgt aaatctggat tgtatgaaac tgaatagagc
    13681 tgtaatggct atcttcacta acagattagg tacaaacaaa aggggcagat tgagaaaaac
    13741 aggcagacaa cttacgacaa aggaggcaac aagatatggt aaatctaaaa tgcttcggta
    13801 tgttgctggc gagggcgaac ctattttccc tgttggatat atccaacaca gaaaaccaat
    13861 ggcaaaggtg tatttagcga attgctacac tctagaggga agaaaattta tccacaccaa
    13921 tctaagtgtt gataaattac tgatgtacca gttaatgaaa ttatctttgg aaaatcgcac
    13981 aatagaatac gcagacaatc gaatttcgct attttctgct caacatggaa aatgtgctat
    14041 aactctggaa gaatttcaac aagctaatga aatacattgt catcatattg taccaactgg
    14101 agctggtgga aatgacgatt ataaaaatct tattttggta aaagaggcgg tacaccgtct
    14161 aatacacgct aaaacagaag aaacaataca aaaatatata gctctattga agctaaataa
    14221 agtccagctc ataagactaa ataaatatag agtattagct ggcaatcaag aattaaactt
    14281 gatataggtc tactacataa atacttttca atataaacac gatggaacgc ggagtgcggt
    14341 gaaagtcgca cgctccgtgt gaatgggggg aaaagtttga gatatttata atatcaggaa
    14401 cttacctatc catatatcaa tggtttttaa ccaatgctca atctttagtc ttactagcga
    14461 ttgtggtcat tggtttgttt ttaggattta aacgggagtt ttccaaactg attggcttct
    14521 tggtgattgc tttgattgcg gtaggtctgg tctttaatgc ttctggtgtg aaggatgtcc
    14581 tactcaattt gtttaaccga attgtcggtg cctgaggggg aatcacaatg gaacagatgc
    14641 gtgtttatat tgcgaacctt ggaaaataca atgaaggtga gttggtgggg gcatggttta
    14701 ccccacctgt cgattttgat gaagtgaaag aacagattgg attaaatgac gaatatgaag
    14761 agtacgcgat tcatgattat gaactgcctt ttgagattga tgagtatacg ccaattgaag
    14821 agattaatcg gttgtgtaac ttagcggagg aactagaagg aacgccaatt ggtgaagctg
    14881 cttctgagat tcaacacgct ttcttcaatt ctttcgagga aatggtagag catgtggatg
    14941 atattgtcta ttatccagat tgcgatgata tgagtgatgt ggcgcattac ttgattgtag
    15001 aagctggtga ttttggcgaa gttccagaac aattgaagcc gtatattgat tttgatgctt
    15061 gcggtcgaga tttggagatt ggaggaaatt atttggttac tagtcgtgga gtttttgagt
    15121 atccagaatg aatcaaacac tatatatagt gtttgattag tatatgtaag caaaaaaaca
    15181 caatatatag agtgcaaact gaagggtaat gtgatataat atttgccgaa gaaatatttt
    15241 tgaaatgagg taatattatg gcaaatattc aaacaagttt tattgatttc cataattcaa
    15301 ttagattgga cgtagaagac aatacgctac ttaaggacta taaagaccaa gtaattgatg
    15361 gattaaaaga ttacttacct gatgatgtga agtttgaaac ttttttacag ggaagctatt
    15421 ctgtttatac cggaataaaa agctgtgatg aaaaaattga ttttgacatc gatattgcag
    15481 ttgctttcga aattgatcat actgtttatg aagatccaag ggagcctaaa ctgtgggtaa
    15541 aagaggcgct agttgaaatt tttcctaatg ctcaagttaa tttaaaagta ccttgtgtaa
    15601 ctgctacatt tactggaaaa aagacaaaaa aaaatgtgca cgttgatgtt gcggtttatg
    15661 ctaaagaaga tgaaaattat ttcttagcaa aagcaaaaga attcagtgct cccgaaaacc
    15721 gatgctggga ggaagcggat cccaaagtat taaaagagaa aattaatagt catgtagcag
    15781 attcagatga tcgaaaacaa tttcgaagat gtattcgcta tttaaaaaga tggaaagata
    15841 acaattttaa ccaagaatat aaaccaacag gaattggact tacaattaat gtgatggata
    15901 cgttcctagt taataagtcc actgattttt taactagaaa agttcagtat aatgatatgg
    15961 aatgtatgaa gcagattgtt tcttcgctga aagattcatt tgtgtatgag tacagtgaaa
    16021 cagatggttg gcattatcgt ctacatgcat atcttccagt gaagcctaac agtgacacct
    16081 attcaaaaat gacagtgaat cagatgagtg attttaaaaa caaactttct aaattatatg
    16141 atgatttgat tttcgctatc gatactgaag atgagtatga agctacaaaa cgattaaata
    16201 atcaatttgg ggaggatttt ttaattattt cagaagaaga agttacagaa aaaaacttaa
    16261 gaaatgcatt tgttacagac tatccgagtg cttaggttgg tgttaaagat tggattatac
    16321 tgatatttta aaagaaaagc taacagatgt tgtgcgttta ttcgatggta attactatgg
    16381 ggatttttca tttgctacaa ttggaaagtt gcgtttaaaa attgaaatac caaaacattt
    16441 tccattggta cttcctagga tttacattca taattttgat catttaggac tttacctacc
    16501 acatgtagaa aaagatgggt tggtatgttt ttcttcagat ataaattatt tagtagatga
    16561 agaaaattca gaattggttt tattgcagtg tgttaataaa actataaaaa caattgagga
    16621 aggtttgaaa gggttaaata aaaatgattt tcgaaaagag tttgttgctt tttgggacaa
    16681 acaagagaat caaatttcgt tattctacct ttgtgaacca gcgttgttta tcaagtcagt
    16741 tgatacaata atgtacggta agtctttggt tgctttggat aaagagaacg aattacaatt
    16801 aaatgcagcg agtagattgt ttaatggaga gaaagaagat actcatgaat tagatgcata
    16861 ctatgttcca attagaaaca agaataatat tatgcccccg aagaataata aagcatggtc
    16921 aaagaaggat attttacaaa tagtaaaaaa aaatgtaaca ggtgcaaata aaagattttt
    16981 tttaaaactt gaaaaaagaa agaatagaca taatgtttta cttattctag atatcccaat
    17041 tgaagaaaag tcaaataatg tcataattgg atttcttttt acaaaacaat ctggatctat
    17101 aaaagattat aagggtacgc ctaggactgt attagttcag cgtcatgatg aattatattt
    17161 ggtgaataga acgagcggag aaaactatgg attgggtgct aatatagcta ttgttggggt
    17221 agggtcagtt ggcagtaaaa ttgctgaaaa tcttggtcca ttaggtgtga gaaagatgac
    17281 actcatagac aatgattgtt ttcaagctga aaatttgtat cgaaattcac ttggtgcaga
    17341 tagtttaaaa aatgcccgat ctcagaataa tttttttaaa gttgatttaa tgcaggagga
    17401 gctcgaaaaa aaaatcccat acctttgtgt tgaagtggag tcaatgaacg ttttagactt
    17461 aattagtatg caacctggtt ttttcaagga atatgactat gtttttgttt gcataggaga
    17521 tacaatggca agcctggctt taaataatta tttttccaaa agtagtcaaa aagttttcta
    17581 ttcttggctg gagccatatg gcattggggg acacactcta tttataaatt attctctaaa
    17641 tcaaaaaggt tgtttcaatt gtctttatac agattcaaac tctaaaaata ggtgttcaaa
    17701 tagagcttct ctggtaaaag aaggacaaat ttttgaaagg actttagcga gttgccgctc
    17761 aaaatttata ccatataatg ctattgcctc gacggaatgt gcaattaatg caataaaact
    17821 tttccataaa gtcaatcaaa ataatatgac caatagtact cttttttcat ggataggaga
    17881 tgggagtact tttgagaatt taggatatca atatagcgac agaaatactt ttcttaatgg
    17941 agtcaataag tttgaagaaa gattcttttc taaatattgc aaagtatgtg gggagttaga
    18001 tgattaaatt ttcgtgtgac cgtattgtca ttgaagtaag ggatgaagtt cttaagatat
    18061 ttgaacaata tcggcaggga aaggatgact tgcctgaagc tggaggagtt cttcatggaa
    18121 aaagacttaa gaatgggagc ataataatta ccgatataac aacacctcaa ataggagata
    18181 tacaaaaaag attactcttt aaaaaaaacc gagaaattca tcaacagctt tctaatgaga
    18241 aatggataga atcaaataag ttttctattg cattgggaga atggcatact catcctgaag
    18301 ctgtaccaac tccatcaaat gttgataaga aaagctggag actgaacgtg agcaagcaac
    18361 atgatgatag agtttatgtt tttattatcg ttggattttc tgatttgaga atgtggttac
    18421 tgtcaaaaaa atcagatatt aggcaggcta taaaactata aaggagtgat taggtgaaat
    18481 cacaaaagaa tatttggtgg tgggggtttt tagtaggaaa ggtaatgata ccagcccttc
    18541 tcttaatttc tctaccgatg attacttttt tctttaccaa taaaaaaatg agtaaagaag
    18601 ccgtgatttt tttctttgga gaccaaaaag ctacctttat tgaaacgtta gtaacatctc
    18661 ttcagcttaa tttgaattac attttttcaa ttattattgt tatatcgtta ttgaattttt
    18721 ttaaaaaaag aaattcagga aaggtgttta actctaatgg aaatgtgtac tacaactatt
    18781 tttattttgt attttgggta gcagcaactt tacttggtta tgataaaatt cagattgcag
    18841 gaattcctat acacatgcaa tataagttgg ttttgagtgg aattttttct gaggtgttgc
    18901 cagatatata cgatgatcat tacgacagtg atggaacatg taaagtaagc attgaaaaag
    18961 aaaatttcga tgacatcgat ggatatgact ctgtgaactt actgattatt gatacttacg
    19021 atataaaaat gagtgaatta tctatggaaa atcaaacata tcctacgata attgttagag
    19081 ggaattcaat agatggagtt cgtaaagtta atagatcttt aatcttggaa ataaaaaaaa
    19141 caatggatga aattcaaaaa agtgacttta aaaaagtatt tgttgcttca acatctaatc
    19201 caaaaaatag tatcaatatt attaattcat cgtttagatt tttcggtcga tcacgtaggt
    19261 ttaaacttta tgttcttcaa aaggattatg caagcaatgg aaagtatagt aagaaatata
    19321 gaatttttat ttaagaagga atttttcctt ctttttattt tggaggaaac tatgaaaaaa
    19381 ataaaaagct acaccagtat ttgggcagtt gaaaaagtca tttatgcgat taatgacttt
    19441 cagctgcctt ttcctgtgac ctttaaccag atggcttggt ttgttttatc cttgatgttt
    19501 gtcattgtat ttgcccatgt gcctccgcta tccatgatag agggggcttt tttaaaatac
    19561 ttgggcattc cgatagcggt cacttggttc atgtcgcaaa agacctttga cggtaagaaa
    19621 ccattgggat ttttacgatc ctttatcagc tatcacttac ggtttaaggt cacttttgca
    19681 ggaaagaaag ttaaagaaca gaagaaacga tgggacgaac caatcacctt ggtaaggagt
    19741 gtgaattatg tacccgatta agtatattga aaataatctt gtctttaacc aagaaggcga
    19801 gtgttttgct tactatgaat tagtgcctta caattactcc tttttgtcac ctgaacagaa
    19861 gtatcaagta catgataact ttcgccaatt aattgcgcaa aatcgtgaag gtaagatcca
    19921 tgccttacaa attgccacag aaagtagtat tcgtgccaca caagaacgtt cgaaaaagga
    19981 aattaccggt agactcaaag aagtagcaaa gcaacgaatt gatttacaga cagatgcatt
    20041 agtatccatg attggcgata gtcagattga ttatcgcttc tttattggct ttaaactgat
    20101 ttcgacagat gaagaggtca atctaaagaa tctcaggaaa tctttctttt ctggacttca
    20161 agaatttgtc tatggagtga atcatcattt gatgggtgat tttgtttcct tatccaatga
    20221 agaaattcgt cgctatacca agcttgaaaa actaatggaa agtaaattgg ctcgaagatt
    20281 taaagtcaaa cgagtaacgc cgagtgactt gacgtattta attgaacata tctatggtga
    20341 aaaaggcaca ccgtttgaag aatatgaatt ccagctacca aagaaaaagc tgaaatcaga
    20401 aacgctggtg aaacgttacg acttattacg tcccactcgt tgtttgattg aagaaaagcc
    20461 tcggtactta cggatggaac atgaaaatca tgagtcttat gtagcgtact taacaattaa
    20521 taccattgta ggggaaatgg agtttccttc ctcggaactt ttctattacc agcaacaaca
    20581 atttacgttt ccgattgata cttcaatgaa tgtggaaatt gtgacgaata aaaaggccct
    20641 agctaccgtt cgtaataaga aaaaggaatt aaaagattta gacaaccatg cctatcaatc
    20701 tgataatgaa acgaactcca atgtattaga tgctttggat tccgtggatg aattggaaac
    20761 caccttggat cagtcgaaag aatccatgta taaactaagc tatgtggttc gagtgagtgc
    20821 taaatcagtg gatgaattaa aacgccgctg tgatgaagtg ctcgattttt atgacgatac
    20881 caatgtaaaa ctagtccggc cctttggcga tatgatgggt ctacacaaag aattcttacc
    20941 ctcaagtaag cgatacatga atgactatat tcaatatgtt acgtctgact ttttggcggg
    21001 acttggtttt ggggctactc aaatgctagg agaattagaa ggcatttact ttggctataa
    21061 cgtagatacg gggcgcaatg tttacctgaa accggcattg gcatcacaag gggtcaaagg
    21121 ctcagtaacc aatgctttgg catctgcttt ccttggttcg ttaggtgggg ggaaatcttt
    21181 tagcaacaat ctcttagtct attatgccgt cctttttggt gggcaagctg tgattgtcga
    21241 tccaaaagga gaaagaggcg gttggaaaga aacgttgcca gaaattgcgg atgaaattaa
    21301 tattcttaac ttgaccagta agccagaaaa tcaaggctta cttgatccct atgtgattat
    21361 gaagaaaaag aaagactcag aaagtttggc gattgatatc ctgacctttt taacagggat
    21421 ttccagtcgg gatggggaga agttccctgt gttacgcaaa gccattcgaa cggttaccca
    21481 aagtgatcag cgaggattat tacaagtaat cgttgaattg cgtaaagagg actcaccagt
    21541 cgcggaaaat atcgcggatc acatcgagtc ctttaccgat tatgattttg cccatttgct
    21601 tttctcagat ggttcgatta cccagtcgat tagtttagat aagcagttaa atatcattca
    21661 agtagcggat ttggttttac cagatgcaga aaccactttt gaagaatata ccaccatgga
    21721 attgctgagt gtttccatgc taattgttat ttccactttt gccttggact ttatccatag
    21781 caaccgagaa attttcaaga ttgtggacct ggatgaggct tggagttttc ttcaagtagc
    21841 tcaaggaaaa acgttatcga ataaattagt gcgtgctggt cgggccatga atgccggtgt
    21901 ttacttcgtc acgcaaaaca gtgatgactt gttggatgaa cgtttgaaga ataatattgg
    21961 gctaaagttt gcatttcgca gtaccgatat tcatgaaatc aagaaaacct tggaattctt
    22021 tggattagat aaagaagatg aaagtaatca aaaatgcatg cgagatttgg aaaatgggca
    22081 atgcttgatg caggatttgt atggtcgagt aggtgtggtc caagttcatc cagtctttga
    22141 agaacttttc catgcttttg atacccgtcc gccagttcaa gagagaatgg agtgaggaga
    22201 tgaaaaagaa actttttcgt atctttggaa ttgttttaat cagtttggtc actctgataa
    22261 tacttttgag cttagttgga acggtagctg aggcaacagg tctggttgat gatacagttg
    22321 gagccggaaa tctttattcc caatattcac ttggtaacta tcagttggat ttctttgtgg
    22381 atagttcgtg ggattggctg ccttggaatt ggggtgatgg cctagggaag agcgtaatgt
    22441 atggacttta tgccattact aattttattt ggacagttag tctctactta tcaaatgcca
    22501 cgggctacgt ggttcaagaa gcctataagc tggatttcat ttcagatacg gctgaaagta
    22561 ttgggaagaa tatccaaacc ttagccggca ttaccgaaaa tggactccag acctcgggct
    22621 tttactttgg gtttctatta ttgatgattt tagctctagg agtttatgtg gcgtatacag
    22681 gattattaaa acgagaaact accaaagcag tccgggctgt cattaatttt gtgatgattt
    22741 ttctactttc gggttcgttc attgcgtatg cgcccaccta tatcacaaaa atcaatgatt
    22801 ttagctcaga tgtcagcgaa gcggctctta gccttggaac cgagattgtc gtgccgaatt
    22861 cagaaagcca aggaaaggac agtgtggatt taatccgaga tagcttgttt tccattcaag
    22921 tccaacaacc gtggttactc ttgcaatttg atgattccaa tatagaagaa gttggcgaag
    22981 atcgtgttaa caaaatcctg tctgtaagtc cagatgaaaa taaaggcaag gatcgggaag
    23041 aagcggtcaa agcggagatt gaagataatg acaatgcgaa tctcagtatt accaagacca
    23101 tgaaccgctt agggaccgtg gtctttttgg tgttgttcaa tattggcata tccttctttg
    23161 tctttctcct aacagggatt atgttgttct cgcaaattct ctttattatc tttgcgatgt
    23221 ttttgccgat tagtttctta ttgtccatgt tgccgactta tgagagtttg ggcaagaagg
    23281 cgattattcg cttgttcaat acgattatga tgcgagcagg agttactttg gtgattacga
    23341 ctgcatttag catctccacg atgtttttca atatttcggc aacctatcca tttttcatgg
    23401 ttgcttttct gcaaattgtg acctttgccg gtatctattt caaattgggc gacattatga
    23461 atatgttcaa tctccagagt aatgatagcc aatcaatggg aagacgggtc atgcgaaaac
    23521 cgcaaatgtt aatgaatcga acattgcggc aactcaatcg aaatgtggga cggactttgg
    23581 cttttggtgg tggtgcagca gttggaaata agttggcaaa ggaacaatca aaatccaaat
    23641 ttaagccatc cggttcttct ctacgaaaga attcacgatt accgaacgat cacgagatac
    23701 catctgactt gaataaggaa aagccaattc caaataataa gaaacaatcc cgaatgaatt
    23761 tggccgggag aaaagtcggc aaggttctgg atacccaagc tttggtgaaa gataagacca
    23821 aacaagtaaa ggatggagta cggaatacgc caaccaactt gaaatacaac ttccataaag
    23881 gaattgaaaa aacgaaaaaa gcaccggaag agtttaagcg aggactggtc caagaaaaag
    23941 caaatcgagg agagttgcga gaaaaacaac aacaacgtag agacgaaaaa atagctgaaa
    24001 agcgcaaagt attgaacgaa atagggaatc ctcatgggaa aagaagggaa aatgttccga
    24061 taaaagcaaa ggtccaatct caaaaggata gagcaccaaa gcggattgtg agagcaaatt
    24121 cgaatcccga aatcaaacga aaattcgcta gccaagaaat catttcaaaa ggaataaacc
    24181 aatcctcaag taagaaaaat tcttttcaac aagtgaaacg gcggtctact ctgtccaaac
    24241 gaaccaatcg aaaagtacaa aaaagtttga accctcatcc caaaccaagg tcaggtgaga
    24301 aaaaatgaac gtaaagaaat taagtgccat ttcgttaact ttcctaacaa tctcttttat
    24361 gggtatcttg atgtgtgtgg gcttattgtt tggtgaagac agtgaaggaa gtagtagttc
    24421 aggtgctcct cctgggggga gtagtgtctc agaagaggtt ttgaaacacc gtgcaatggt
    24481 ggaaaaatat gccaaagaat cggatataac agagtatgtt ccgattcttt tagcgattat
    24541 tcaagtggaa tctggtggca caatggaaga tgtgatgcaa agttctgagt cagccggttt
    24601 accaccgaat tcattaagta ccgaggcatc catcaaacaa ggatgtctct attttgcgtc
    24661 tttggttaag cgttccaaag aattaggttg tgatcaagat agtatcattc aggcctataa
    24721 ctttggcggt ggttatttgg actatgtggc aaaaaacggg aagaagcata gttttgcttt
    24781 agctgaatct ttttcaaagg aaaaatcttg cggtcaaaaa atcgattacc ctaatcccat
    24841 cgcgaataag gaaaatggtg gatggcgcta taactatggc aatatgtttt attgcttatt
    24901 ggtgaagcaa tacctaacta caacacagtt tgacgataaa acagtccaag ggatttttga
    24961 cgaggcgttt aagtatgaag gaacggctta tgtatttggt gggtcaagac ccgaaacagg
    25021 atttgattgt agtggcttga ctcaatggtg ttatgccaaa gttggtctga aacttcctcg
    25081 ggtggctcaa gatcagtatg atgccatgac ccatattgac ctaaaagatg ccaaaccagg
    25141 ggatttggtt ttctttcatt cgacttatga tgccggtact tatgtgaccc atgtcggtat
    25201 ttatgcaggg gagaatcgca tgtttcatgc aggagatcca gtaggctgga cgaatctaac
    25261 agaaagctat tggcagcagc atcttatcgg tgctggacgg tacaaataag agaaaagagg
    25321 aaaaagaatg aagataaaaa ttgaacggaa tcaaaaggaa aagagcctaa aaaagaaaaa
    25381 agaacgagtc gtatccgtgg gtaagcatcg aaaaatggtg cttgcccttt ggcttttatt
    25441 atcttgtagt cttacttttg gcgtttataa aaatttcacc gccattgatc aacatacaac
    25501 tcatgaaaaa gtggttatta aagagaaagt agtgaatact tctggtattg aaaactttac
    25561 gaaggatttt tcgaaagaat atttttcgtg gaaaaataac aaagaagcaa ttgaaaagag
    25621 aatgaacaac ctcgaacagt accttacaga agaaggtttc gctttaagtc aagatatggt
    25681 tcgagcagat attcccacta attccgaagt tcagtcagta aaagtcttag atgttgaaaa
    25741 gagctcggag gaatttgtcg tttcattttt agtggagcaa aagattacag agggaaaaaa
    25801 ggcacaatcg atttcttctg cataccgagt gacgatcttt gaagatgaaa acaggaatta
    25861 tatagtaacg agtttgccaa ctatgattgc aaaacctgat agggcaaaat acaagacaaa
    25921 acaagtagaa aatgattcga aaattgatgc caaaactaca gaagaaatcg ctgagttttt
    25981 ggaaacgttc tttaaattat atccatcagc ttctgaaaaa gaattggagt attatgttga
    26041 aaatgatgcg atgcgaccaa tcaatattga cttaaagttt tcgaagttag aggatccagt
    26101 ttacctacaa aacggaaaaa aaattctagt gagtacaaag ataaaatacc ttgataatgt
    26161 atcaaaaacc actagctact ttcagtacaa attaatatta caaaaaaatg gaaactggaa
    26221 aatcattgat gttaaataat aatgactcaa tctaaattta tgagaagtta taagtagttt
    26281 aacttatttc aggcagaagt cgcccatcct ctataggtgg gtgatgaatg ccgttcggta
    26341 actcgaaaac cgacaattaa gacatagtgc ctttttattt taatccatgt cataatcagt
    26401 ctatataaga aatggttgat ataccatgga attagataca aataatcatt cattatttct
    26461 tctttgttac caccttattt tagtagtgaa acattgtaaa catctcattg atgatgtaat
    26521 gttagcttat gcaaaaaact atctttgaaa gaatatcaga atcacatcac attaccttag
    26581 ttgagtgaaa tcgtgataaa gactactttc atattatgct caaagcacaa cctaaaaccg
    26641 aattaacaaa attcagcaat gcctaagctc atgtctgata aaatgagact ttctaagggt
    26701 caaaaatttc ctttgaatac gatcattagc ttagataaaa gtaaaaacct tagaactacg
    26761 gggatagctt ggttaataag agatatcgct gttaataaag acataagctt gcaagtatgc
    26821 tctattccca agaatctccc acttcaagca ctaaggatcg ttaaattcag ctaagtggca
    26881 agtagttcac tagacgataa ttatctccat atttcaatct cagcttttcc atttttcata
    26941 gcaaattccg ttatttttat agcatctaaa agattcagct tttccactga tctttcacca
    27001 cttttcagct tttttattgt gcttaaattg ataccagtac cttttgatat tgaattggaa
    27061 gtaaaatcat taagggtttt ttttattaaa ttcatatccg caattccagc gttcataaga
    27121 atgaagattc tcctctcata gactactttg aaaatggtac tacagtggct gtttatatat
    27181 ttcagtaggt tactgtagtg gtcattttat tataattaga aaaggaacct aaatcaaaaa
    27241 tgctaaagaa aattttcata gtattaaacc tatcatgact aaagccacgg aattcttgat
    27301 aaaagagtat acttgcaagc ctatgtcttt actaacagcg atatctctta ttaaccaatc
    27361 tatccccgtt gttcctaagg ttcttgatgt tttctaaggc aatgcttgta tacatagccc
    27421 ttgatcaaaa tattgatact aacgttgacg tttcgatcat gatgtgtacg gcaaatagga
    27481 caagtccatt ctcgaattgt gaatgacttc ttaccatctg tgtgtccaca ttctgaacca
    27541 atttgactag acggaaatca tttatctatc ttgatgattt ttttgacaga agtatcgaaa
    27601 atctttacat aatctgggtg ttgcattctt atgcagatga gagcgttagc tccgtattca
    27661 taaccagttg cctctaaaac gtagtccatc ggtggatacc tagcttgcgg ttgccagtgg
    27721 ctttcgcagt cttcttgtaa tcaaatcgag catctaattg agtactagta ttttgaagat
    27781 aatacttgag tttttcggtt ttcagaagtt cacttcatct tccatcatcc atggaaatcc
    27841 cactcaccca tacgcaggcc tccaaaaatt cttcaacaat ggtttttcag acatttttct
    27901 gaatacctcc ttgttttttg atacgccaga tagtcaggaa aaaggcaaca aaacacaaaa
    27961 caaagctgcc taaaaaggta atcttcattc catataaaaa gacatccggc cgatctgcga
    28021 tatagttagt tactcgttgg cccatcttag cagacatcgc ttgatataag accgtcgtag
    28081 aaagcgaaat cccgatgacc atccccaaat ttcgggcaaa ggaattcatg gagcctgcca
    28141 gtcccaaatt ttcgatagtg acagaactca taaccatcgt attatttggg gactggaaca
    28201 aggcattgcc ggcacccatg atggcagtag cgacaatgta cagccacaaa ggagagtcca
    28261 ctgacaaaaa catatacatg acttgggtta ccgacaataa acccaagcct actaatacaa
    28321 aaatctccgg gccaacccgg tcggtcaggt atccgcttaa aggcgccccg acgaccatca
    28381 tcaagggaaa gaccatcatc aacagtccgg catagctagg actcaacccg cgagcatttt
    28441 gcagataaaa aggaatcact acattaacaa agaagttgga agaaaaaatc aacaaggctg
    28501 taatcaagct catggtaaaa atcttgttct taaaaatacc gaaagaaatc aatggagagg
    28561 ctgctttctt ttcaactttt aaaaagctga caaaggcaat cactgaaatt acgaacagta
    28621 caagggggac tggatggaaa aagccacttt cttgccccaa aaagattgtt ccaaaaaggc
    28681 tgataatcgt agccgcaatg gcagcaaagc cccctccatc gattgtatgg ccgctcatgg
    28741 tgatatcttt tggtaagaat ttttcagcaa tcaacatcgt tacgattccc accggtacat
    28801 tgatccaaaa aatgtacgcc caagaaaatt gggacaaaat caagccgcca agacctggtc
    28861 cagcaatcga gcctaatgaa acaagcgcac cgattgctcc caatgcccga ccacgttcat
    28921 gtatgggaaa gacttccgtg atgattccgg catttgtagc catagtcata ctagcaccaa
    28981 tggcttgtac cacccgtgcg aacaattaaa tacctagcga atgattgaac ccacacaaca
    29041 gcgagcccaa gacaaagatc agcgtaccaa tccgaaatac tttgattttc ccacagctat
    29101 cgccaatttt accaaacagc aacaaacaag aacagacaat catcagataa acggacacta
    29161 cccattccgc ttgattcatt ggtatgccca tatcatctga gatggtaggt agtgcaatat
    29221 tgacaatact gccatccaat gtggacatga aggtaaacat agatatagca atcaaaatcc
    29281 accagcgatt tttttggact tttgcatctt cttgataact atgcataata ggatttcctt
    29341 tctaatgatc gtgtagctaa gaacaatata acctatgtct actgcccaac aacttctcgc
    29401 gactctagcc ataggaagct tgagtaattt cgatttgtta ttctcatgta accatgtaag
    29461 tttgagatgc tttatttgaa cttactctat agtaactagt gataattcgc tttactttct
    29521 tctagcaatt tctaaaagtc gacttcattg ttcttcagat taatagtgtg agctatctcg
    29581 tgagacgtaa gaaaatttcc attctacttt ttcccaattt tttcatattt atggtgttgc
    29641 acctatttgt tttccaattt gcttttcaaa tacattgcta tgatattcaa ttccatagga
    29701 ttatactaaa tgtcaatagt atgaataata tattatagat gtttatatat cactgttaat
    29761 tattatccac aataattaat gattacctcg atatttgtca atcaaaggtt gaaacaattt
    29821 attttcagca tcttttctaa cttgagctgc actcttaata gaatcatacg atcctaaata
    29881 gtacctcttt tttttaaagt tatatacgca atccatttct ctttagaacg ataaactccc
    29941 ttaacaccac ttgtattatt tttcggtaat tttgacgtta gacactctat tactgtccct
    30001 tcaacacatg tccttgtttc ttgccttttt aaacatccac aactttgagt atgtccaaaa
    30061 aataagttac tataacttat ctcacacata ctgccacact cacattgaca aacccatttt
    30121 gttttccatg aacagttatt gtccaaagga tactttgcag taagtaatcc gaatttttta
    30181 ttttcaatgt gatgcttttt tgatttcaaa catccacagc tttttacatc accttttaga
    30241 agtcgctttg ccgatactaa cttttttctc ccacacagac attgacattc ccaaacaaca
    30301 gttccttcac ttcgcagttt agttggcttg attgcaacta acttaccaaa agttttattt
    30361 gtcaaatttt tatatttatg cctattttta taatttccac atccacaact tttggttcta
    30421 cctgatagta agtttgatcg atatacaatc gtttcattcc cacagtcaca taggtaacga
    30481 tattttttat atccattatg agtaatctcc tcaacaacag taaggtgacc atatctttcc
    30541 ttcactgcac ctaccctccc aagaaagaag taccatataa tttcaattaa cttttaataa
    30601 atcagaaaaa aatattttca atttttctta gtctgatttt atgactaatt tataatacaa
    30661 gactgaacga tacgtacacg aaatcctcaa gatagataaa ttgttttcat ctagtaaaac
    30721 ctgctcaaaa tatgagcata aagacggcaa taatacactc gatattcgat aatggacttg
    30781 ttttatttgt caaactcatc gtaatcgaga tatcaattcc agtctcaata tcctgatcaa
    30841 aggtctaaga atccaaccat tttcttgtta ctttgtcaga ttgattacct tttttagtct
    30901 ccgaataata aggttttcgg atcaactaac atgctctgag aaagactact atctttgcaa
    30961 atttccaaat gaaggtgtgg gccagtacta ttcccagtac ttcctacata gccaattatt
    31021 tgtccttgca aaacattatc tccagttttt actaggtatt gttgctggtg agcatataac
    31081 gcggttgatc catcttcgtg ttgtatcacc acgtaatttc cccaagagta gtgaaactct
    31141 gctttaacaa ccttaccagc tttaactgca tgaatcggct caccctgtgt agctgccata
    31201 tcaagtcctc ggtgaaattc atttccacga tttccaaaca aactggttat tgaataatta
    31261 tgaataggca cttggtatcc agtcttactc atttgtggac ctttaacttc tttatcatag
    31321 ttggttaaat cataggtttt aattaattca tttagcttca aatagtattg tgtatctgtt
    31381 gcataccgtc ctgtaaggaa tttagttgct tctcgatatg ttttactatt agcttttaat
    31441 gctcctgcat aaaaatcttt atttccacta attcccttag ttaataattt ggcataatct
    31501 tcaaaacttt cctcatagtt ttcatacact ctaaattttg attgggtcgt ataaagcgtt
    31561 ccattaccca aatcttcgtt tgttaccata atgacaaagt ttccattata agttcctttt
    31621 atcccaaata aattgtaatt cggtgcctga gctaactggc tttgaccact ggcagattct
    31681 aagatcgctt gtgcaatcat aacagaagca tataaatcat atttctgacc aatttttctc
    31741 gcagactcac caattttcat aataaaattt tctacagatt catttttgtc aaaatgaatt
    31801 tcttcattac cagatagtat tggttgtgat tggaaagatt ctgttgattc tatttgctgt
    31861 ggtgtcgaaa aattttttgt ttgtccttcc gtttttggcg cttccttttt tgaagactct
    31921 atatggtttg gtcttgtcac tttcgaagaa gttatttcac ttgtactact tgaagttgtt
    31981 gaagattcgg cacttgaaat cgtactactt tcacttgacg aagttgttga agactcggca
    32041 tttgaagtcg tactactttc acttgacgaa gttgttgaag actcggcatt tgaagtcgta
    32101 ctactttcac ttgatgaagt tgttgaagac tcagcatttg aagtcgtact actttcactt
    32161 gataaagttg tcaaaagttc actactctct gctgttacat cggaattact catttcagtc
    32221 gtctcggttc tttcttttgc aattttgtat gttgaatttt cgcttgccaa cacatggaaa
    32281 ggtgttgcta taaagagttg ggacattaat ataactgctg atgcaagttt taaagatttt
    32341 ttcatttgat ttacctctct tttttctctt taatagtgtt ttctattaaa aattatgata
    32401 aatattttca atgaattgag taatacagta tatttcttga tttcatttag taacgattat
    32461 gtttcaatgt ttaatcctgt tactgccttt aaaataaaat tatagggttg gctaaaacta
    32521 ggatgaaata aataatctaa cattttcaat ttgtctaatg taatttgttc ttctatagca
    32581 agagaaaaca ttgataatag tccagataaa tcttcttgac tacaaagttg tacacctact
    32641 attctctttg tatttttttc aaagctaatt cttaatttta cacgactatt ttttctcaaa
    32701 aaaacaggtc taatgaaatc ttctatttct atataatcta tagactcact taataatcgt
    32761 gctgttttta aattcaaacc tgctgcgtaa aaattgtaat taaatataga aaagccattt
    32821 gtaaattggg aaccagaagg tgtaaaatct tgattgtcaa tatgttgagt tgcaatataa
    32881 gctgttctta gagcattaga aatagaaaaa tcaacactac ttctattaat ggacgtaaaa
    32941 aaagttgtag cacaatcccc aatagcatat atatctttta tatttgtttg ctggtattca
    33001 ttagttagat atgctccact aacatctctc aagagttcct ttttgccaat tggactatta
    33061 gatagaaatc ctatagcttg tacgaccata tccatagagt attgggtacc acttgtagtg
    33121 actatttttt caatcttttt tcttcctaaa tattttttag gactttctga tagacaaaga
    33181 tgtattccat tttttgatag tatttcttca actttatctg aaaaactacg gtcgtaataa
    33241 gtcgacaaca ctctatctgc aacatcgaaa agatatactt ctttccctct ttttcttatg
    33301 gcttcagcaa tttcaactcc aatatatcct gctccaataa ttcctacttt tttaatagta
    33361 ttatcatcta aagctttaaa aatctcttta gcatttggaa aattctttat cgaaaaaata
    33421 ttagctaaat tattccccgg tacatctaac ataatttgct ttgaacctgt agctagtata
    33481 agtttgtcat attcttggga aaatcttgtg ccatcttttt ttacacaaat aatcttttta
    33541 ttttgaatat caattttgtc aactgctgtc tccaaaaaca acttttttat cttagaattt
    33601 agttctcttc tattttgata aaaaagatct tctaaattgc taacttctct ttttatgaac
    33661 aacgatgtcc cacattctaa gtaactaatt tctgattttt tatctatcag aataacttca
    33721 taatttgaat cacataagtt tagaaatcga gctgcagcta gccccgaatg gtttgatcca
    33781 ataattacta tttttttcac ttaatcacat tcttttccct tctatgaaaa gtatcttcat
    33841 ttttaactaa caacctatct cccaaaataa aaaacaaaaa gaggaagaaa aagattcttc
    33901 ctcttttcag agaagattta agaaattgat tttctattca ttctcttttt ttcgattttt
    33961 ataccctaat aaccctaaag ttcctaacag gattaaacca ccactaatag taaagatatt
    34021 actatcaatc tctcccgtct taggataagc ttttgaggac tgcttttgag gactgctttt
    34081 gcctctattt ttgttttgct tgctaccttg attgtcagtc ttattatctt tactaacggc
    34141 tttttcactg tctttttcgt ttgaagaaac aactacatta gtaggttcac tagtattacc
    34201 agattcatca gttgcagtta ctatcacttt tgttcctgcc tctaatttag gaactttaac
    34261 tgtaaaatta ccatttttat cagctgtccc atggtattga ctcccgtttg gtaatgtaac
    34321 tgtcacctct gcatttggtt cagttttacc agtaacaatt tggtcaccct ctgtaatagg
    34381 atcaacttga ggtttattcg gtgctttttt atcttctaca gaaatagtaa cctctacttc
    34441 ttctttagat ccatctggat atgttactac tacaatccct tttttgtttc cagctgtact
    34501 aacatctact ttctctttcc aagtataagt agttcctttt ggtagatctt ctttgttctt
    34561 aattccctca gatgcgtctg gctctttatt taagtctgta gtcacttttt gtccttcagg
    34621 attgtattta tcggcatcgg aacgattgtc tgtcacttct actggaactt tcactgtatc
    34681 tttcgtacca tctggatacg ttacttcgat aaccccttcg taattacctg gtgtgttggt
    34741 atcaatcgta ccatcaggag tgacatctgt tactgttgtt ccttctggta atgttggcaa
    34801 gttagtaaca ttatctgtta gatctactgt gcctccaact tctacttttt cgccttctac
    34861 tgttggctca tatttatcgg cgtcagaacg attgtctgtc actgtaacat ctacttcaac
    34921 ttcatcagat gatccatctg gatatgtcac tacaacagtc ccttttttat ttccagctgc
    34981 gctaacatct actttttctt tccaagtata cttagtatct tttggtaaat cttctttgtt
    35041 cttaattccc tcagatgcgt ctggttcctt attcaattct gtagtcactt tttgaccttc
    35101 aggattatat ttgtcagcgt cagat
//
LOCUS       DAFLWQ010000026        34960 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.027, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000026 DAFLWQ010000000
VERSION     DAFLWQ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34960
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.027"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            156..1862
                     /gene="efbA"
                     /locus_tag="L1V16_001206"
     CDS             156..1862
                     /gene="efbA"
                     /locus_tag="L1V16_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HBN1275556.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2020..2922)
                     /locus_tag="L1V16_001207"
     CDS             complement(2020..2922)
                     /locus_tag="L1V16_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1275557.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2919..3611)
                     /locus_tag="L1V16_001208"
     CDS             complement(2919..3611)
                     /locus_tag="L1V16_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HBN1275558.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3654..4295)
                     /locus_tag="L1V16_001209"
     CDS             complement(3654..4295)
                     /locus_tag="L1V16_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBN1275559.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4333..4647)
                     /locus_tag="L1V16_001210"
     CDS             complement(4333..4647)
                     /locus_tag="L1V16_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275560.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4635..5987)
                     /locus_tag="L1V16_001211"
                     /pseudo
     CDS             complement(4635..5987)
                     /locus_tag="L1V16_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372436.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
     gene            complement(5984..6916)
                     /locus_tag="L1V16_001212"
     CDS             complement(5984..6916)
                     /locus_tag="L1V16_001212"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBN1275561.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6913..7689)
                     /locus_tag="L1V16_001213"
     CDS             complement(6913..7689)
                     /locus_tag="L1V16_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBN1275562.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7743..10928)
                     /gene="carB"
                     /locus_tag="L1V16_001214"
     CDS             complement(7743..10928)
                     /gene="carB"
                     /locus_tag="L1V16_001214"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBN1275563.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10933..12009)
                     /gene="carA"
                     /locus_tag="L1V16_001215"
     CDS             complement(10933..12009)
                     /gene="carA"
                     /locus_tag="L1V16_001215"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBN1275564.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12014..13294)
                     /locus_tag="L1V16_001216"
     CDS             complement(12014..13294)
                     /locus_tag="L1V16_001216"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBN1275565.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13313..14239)
                     /locus_tag="L1V16_001217"
     CDS             complement(13313..14239)
                     /locus_tag="L1V16_001217"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HBN1275566.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14252..15535)
                     /locus_tag="L1V16_001218"
     CDS             complement(14252..15535)
                     /locus_tag="L1V16_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBN1275567.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="L1V16_001219"
     CDS             complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="L1V16_001219"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBN1275568.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16323..17234)
                     /locus_tag="L1V16_001220"
     CDS             complement(16323..17234)
                     /locus_tag="L1V16_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBN1275569.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17231..17695)
                     /locus_tag="L1V16_001221"
     CDS             complement(17231..17695)
                     /locus_tag="L1V16_001221"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBN1275570.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17700..18398)
                     /locus_tag="L1V16_001222"
     CDS             complement(17700..18398)
                     /locus_tag="L1V16_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBN1275571.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18385..18771)
                     /locus_tag="L1V16_001223"
     CDS             complement(18385..18771)
                     /locus_tag="L1V16_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275572.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18918..20588)
                     /locus_tag="L1V16_001224"
     CDS             complement(18918..20588)
                     /locus_tag="L1V16_001224"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBN1275573.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20771..21004
                     /locus_tag="L1V16_001225"
     CDS             20771..21004
                     /locus_tag="L1V16_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HBN1275574.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21103..21534)
                     /locus_tag="L1V16_001226"
     CDS             complement(21103..21534)
                     /locus_tag="L1V16_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HBN1275575.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21613..22026
                     /locus_tag="L1V16_001227"
     CDS             21613..22026
                     /locus_tag="L1V16_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HBN1275576.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22064..23212)
                     /locus_tag="L1V16_001228"
     CDS             complement(22064..23212)
                     /locus_tag="L1V16_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBN1275577.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23334..23930)
                     /locus_tag="L1V16_001229"
     CDS             complement(23334..23930)
                     /locus_tag="L1V16_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBN1275578.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="L1V16_001230"
     CDS             complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="L1V16_001230"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBN1275579.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27160..27591
                     /locus_tag="L1V16_001231"
     CDS             27160..27591
                     /locus_tag="L1V16_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1275580.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27636..28985)
                     /locus_tag="L1V16_001232"
     CDS             complement(27636..28985)
                     /locus_tag="L1V16_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBN1275581.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29055..30218)
                     /locus_tag="L1V16_001233"
     CDS             complement(29055..30218)
                     /locus_tag="L1V16_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBN1275582.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30347..30670
                     /locus_tag="L1V16_001234"
     CDS             30347..30670
                     /locus_tag="L1V16_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275583.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30853..32202)
                     /locus_tag="L1V16_001235"
     CDS             complement(30853..32202)
                     /locus_tag="L1V16_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1275584.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32271..33224)
                     /locus_tag="L1V16_001236"
     CDS             complement(32271..33224)
                     /locus_tag="L1V16_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBN1275585.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33326..34516)
                     /locus_tag="L1V16_001237"
     CDS             complement(33326..34516)
                     /locus_tag="L1V16_001237"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBN1275586.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         9951 a         7642 c         6120 g        11247 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aattgtttgc tacaaaaaga ggagttgtga caaaattctg tcacaacccc tcttttttga
     1981 tcaacggtgt tcaataaaca gcgttctcat ctgcttttct tagctctgct ggtccagtaa
     2041 ccgagtaagc tctttgataa atctttgagc gatttcactg agcggacgtt tcgccgaata
     2101 aatgatataa aattcattta gttcgccttc tgccaaaggg attaaccgca agtgctcgcg
     2161 aatccctcca atcacaatac cagatcctga agcgtaagca tcagtttcaa gaacgatatt
     2221 catcaaagta cctcgatcac tcgtataaat cactgtttct tgatcaggga tctcgataag
     2281 gtcttcataa aaatacggga aattatttcc atcctgtgta aaacgaactt gaggataaga
     2341 taacaattct tctttggtga tctctgcgtg ttcagctaat ggatgtcctt gccttaaaaa
     2401 aatatgcgtt ttgaattttc caatgctgcg gccacttagc tctccttgtt gtaaatatct
     2461 tctgatacca gcttgattat gctcattcat ataaataatg ccgatctcac tgtgctgctc
     2521 tttgacttct tcgatcactc tcgctgttgt cgtctccatg atccgaaatt gtttgatctc
     2581 gtctttgaat tcctcgagta gctgtgcggt caaaggacct aagaaatcat aatgctgggc
     2641 agcgatcgaa aaattgtctc tcttttcact cgttagatag tgagtttcta atgtatcaag
     2701 ctggaccaat attttctcgg cacgatttaa gaagtcttgc ccttcttctg ttaaatatgc
     2761 ccctcgattc gttcgagtaa acagcgtgat ccctaactcg gtttctaatt ctttgatacc
     2821 agctgaaaga cttggctggg agacaaacat tttctttgcc gcttctctga aactaccatt
     2881 gtttgctaca gcgaccacgt atttcatctg ctgaatattc attgctcaaa ctcctcgaaa
     2941 taataaattt ctcttccatt caagggctgg attggtcggt tgttcggtcg agcatactga
     3001 ccatcgaagg ggagaagaaa ctcttggttc agttttccta catgatccat tacaaaccat
     3061 tggattggcc cgctggtagg cggagttgtc aatgagccaa tataatggaa atggcttttt
     3121 tgctccggaa agaacacatc cggatttacc caatgctcat gtttttctaa gttccaactt
     3181 tccccatttt cttgattata cagccaacct tcctgtacca ttagctggta catgacaccc
     3241 acaactagat tctctttttt gctgttcata tgaacaaaat gaaattcaat atcttcctgt
     3301 tttccgttga tgatatgttc agaaggcaag tggaaatgaa tatctgtcaa ataatagcgt
     3361 tctttcttga actctacata actgagttgg tcaaaaggta ctaaatgaat cgtgtttttg
     3421 aattccttgt cagtaaaccg ttgcttttga taatgaaagg aaagcgtgtc tccttctatt
     3481 ttggtttctt cccccttggt caaatgaata ggcgactgca atggaaattc cgcacctctc
     3541 gcaaaccaat cacataaact cgcccaattt tccggacctt tgtctccaga atagccccat
     3601 tcgacatcca tattcttttt caactatact tccccctgca tctcatatca tttttatttt
     3661 tcttctttct ttacaatcgt tgagacggtt tctaaaaacg cctcttttcc ataaaattcc
     3721 tggttcaata gttccggaaa tatctcttta aagaaatact gaacagaagg ccgatgttca
     3781 aagcttttaa tcgtagtcac tgcctcaatg aacatctcct tataaacttt ttccgggtta
     3841 tttttgatga tttcatcaaa agattcataa agaaggtcaa ccttatctga aatggctaat
     3901 agttctcctt ctacggtttc atcttttcct tcgaacaacc gacggcgata aacttcttgg
     3961 aactcagctg gaatctcttg gttgatgaat tcgtccgtca tcttttcttc aactgtttgc
     4021 agcatccctc ttaactcttt gcttgcgtat ttcaccggcg ttttgatatc accaataaaa
     4081 cgctctgtgt agtcatgatt caatgatttt tcatagagca gtttccaatc gatcggttgt
     4141 ccattcgctt cttcaatgtc tcctagaact tgcgcaatag atgctacacg atacgaatgt
     4201 gctgcaactg tatgctctgt atatttaaaa aatccaggtg cccttgtgat cgtctctaaa
     4261 ttgttcaatc ctaaaataaa ttcattcaac cccataaaag ttacctccct ttgagatttc
     4321 tttttccgaa tatcatatca ttaaataact gatattcgca acatttccgc tctttaccat
     4381 ttttgaaaca gctcccttac caaaaaatag agaaaatcta tatataatag aaaaaagaga
     4441 agagattatt ctcttctttc tgctaaccag tcttagaaaa atgaatttta aaaaaatcaa
     4501 aaactgatca cgatagaagt ttcttttcat acctgatgaa aagatgcttc tcgcaatcag
     4561 tttttggatt tttgctattc caattgatga ttctggagac acaaatcgga tttctctatc
     4621 ttcatcaagc gcgcttaaat ctgccaattt tcaggatctt ttttccattc ttttagcaga
     4681 gttaattctt gctcatcgat ataacgatct tctaaagctg cttcaatcaa tacagaataa
     4741 ttggtcaacg tcataagagg gatttcggct ttttcgaaat ttgcttttcc ttttggcaac
     4801 tcatacgtaa agatagccgc aacaccaagg atatccgcac cttctctttt tgctgcttca
     4861 gctgcttcca agacacttcc gcctgtagaa atcaaatcct cgatcacaac catcttctga
     4921 ccttcaaata tacgtccttc gatttggtta cctttcccat gatctttcgc cttacttcga
     4981 atatagacca ttggcaaatc cagtatttcc gctacccatg cggcatgagg gattcctgct
     5041 gttgcagttc cagcaatcac ttgtacttca gggtaagctt ctttgatttt gcttgctaat
     5101 ccttttgcga tctcttttcg gacttttgga tagctcatcg tgattcggtt atcacagtaa
     5161 attgggcttt tgattccact tgcccatgta aaaggattac ttggatttaa aaatactgct
     5221 tcaatttcta ataagtcttt tgcgatactt tgttcaacat tcattttagg ttagctccat
     5281 tctgtttgaa tcgtttgata tgctttataa ggattagttg actgagtgat tggtcgacct
     5341 ataacgataa aagttgagcc gatctttttt gcctgagaag gtgtgactac tcttgtctga
     5401 tctcctgcga ctgttccttc tggtcttata cccggagtta agcaaacaaa ttcgtctcct
     5461 gccatttctt tgatcgcttc tacttcccaa gcagaagaaa ccacaccatc taatcctgct
     5521 tttttggcac agctagcata atggatcaca cttttttcta aagaaacttc gattagttga
     5581 tcggcatgca tttcttcttc acttgtagaa gtaagctgag tgatagctag aagtagcgga
     5641 cgttttccac cttctggagt cccctcttct aatcctcgca ttgccgcctc catcatacga
     5701 ataccgccag cggcatgaac acaggtgaga tcaacaccaa gctttgccaa tccccgcatt
     5761 gctttttcga ccgtattcgg aatatcgtga agtttcagat ctaaaaatac attatgacca
     5821 gcctctttta gataacgtac gatttcaggt ccttcttggt agaacaattc cattccgatt
     5881 ttcacaaaca atttttcttc tttcgggaaa aatcgaagaa agtcttctac ctcttgccta
     5941 gttgaaaaat ctaatgcaat aattggtcgt tggtctagtt gattcatcgt tcacgttcct
     6001 ctctcacttc tttgattaat ctttccagcg attcgatgcc tagttcgctc attcgcacag
     6061 ggagctcttt aattagttta ggacagatat acggatcggt gaaattcgcg gtccctatag
     6121 ctacagcact tgctccagcc ataaacatct caagaacatc atccactgtc tgcacgccgc
     6181 ccatcccaat gattggaagg ctggatatac ttgctacttg gtgaatcaaa cgaatagcga
     6241 caggcttgat tgctggtccg gagagtccac ctgtttgatt ggctaaaatc ggttttcttg
     6301 tcttaaggtc aatccgcata ccaagaagag tattgatcat cgtaaaccca tctgcccctc
     6361 cagcttcgat tgcctgagcg attggaacga tgtctgttac atttggggac aatttgacat
     6421 agacaggaac agaagaaact ttctttactg cttgtgttaa ttgaaaagca acatcagaat
     6481 ctgttccaaa agcaattccg ccatgtttga catttgggca agaaatgttc agctcgattg
     6541 ctttcacatt tggtgcttcg ccaattttgc tacaaacttc tacatagtct tcttcacaag
     6601 caccagcaac atttgcgatg atgggtaact cattgtactc ctctaattct ggaagaagtt
     6661 tatgcataac aacgtctaga ccaggatttt gcaaaccaat tgcattcaac atgccagatg
     6721 gtgtttccgc cactcttggc gtgggattgc caaagcgggc atttggagtc gttgccttga
     6781 ccatgatcga tccaagctga ttcaaatcat agtattttcc gtattctttg ccaaaaccga
     6841 aacagccgct tgccggcatg ataggatttt ttaattctag gccaggaagt ttgaccgcta
     6901 aaggattctc attcatataa ttacctctcc tattttaaaa atcggtcctt cgtcacaaac
     6961 tttcacactt tttgttcctg tttcatcttc cggcgtatga caaacgcaag catagcaagc
     7021 ccctatccca catgccatgc gggattctaa tgataactgg acattttgat gcgaagaaaa
     7081 cagctgttcc actgtcttca ataacccgtt tgaaccacat gcaaaaacag ctgtaggttc
     7141 cgtcttcgtt cctaacaata aattaccgac atttccgtgc ataccgtatg ttccatcgtc
     7201 agtagcgatt cttgtttctc ctagacgatt aaattctttt tcataataaa cgacttcatg
     7261 tgtggcaaaa cctaaaaaat gcgttggctt aattcctttt tcgactaact gttttgataa
     7321 ctcatataga ggagggacac cgattcctcc accgattata aatacttcgt ctcctgtatg
     7381 aagattggac aaatcaaaac cattgcctaa aggacccatg acatctaaat ggtctccggc
     7441 agaaagagta gagaagactc tagtcccctc accttccacc cgataaatga tacggcaagt
     7501 atttgtttcg tggtcgatat gattcaagct aatcggtcgg cgtaatagca agtctgcacg
     7561 cggcacgaga atatgcaaga actgtcctgg ttgctgcatt tcttttacta gatcaccttt
     7621 caatgtcatt tcaaaaatct ttggtgccag ctgtttttgc tgaacgattt ccatcatttc
     7681 ttgtttcatc tgtcccctcc tgcaacggtt tttcgtcttt ttgtcttaac atgtgctcgc
     7741 cgttaaatag ggttagttga aaaagcacgg gattccatca ctcgaacgat cgcatctgct
     7801 gtgtctaaag aagtaaacaa tggaatacca tgttcaactg cttctcttcg gatgatgaaa
     7861 ccgtctttag aagcatttcc ccgatcttta tcaatcgtat tgacaaccac ttgtgtttta
     7921 ccatctctta ttaagtcgac tacatttttt tctgctgctt cctcagaaat tttcgctact
     7981 gtttcaacga ccagaccatt tttttcgaaa taagcagctg tatgtttcgt tcctatcaga
     8041 ctatagccaa tttctgtaaa acgtttagct aattctagtg cttcttcttt tgtttcgtcc
     8101 gcaatcgtaa ataatacggc tccatattca ggcaagtgta atccagaagc ttcgaatgcc
     8161 ttgtacaaag ctttgtctaa ttgtctgtca gatcccatta cttctccagt cgatttcatt
     8221 tcaggcccta agtaagtatc aactttctgc aatttcgtaa aagaaaagac aggtgcttta
     8281 acatgaactt cttttgtttc tggataaagt ccgttttcat aaccaagtgt ctttagtttc
     8341 tctcccaaaa tagctttcgt cgcaatttgt gccattggaa ttcctgtcac cttacttaag
     8401 aatggaacag tccgacttgc tcgaggattg acttcgatca cataaacctc attttcatgg
     8461 atgacaaact ggatattcat catcccgaca caattcaaac ctaatgctaa gcggatcgtg
     8521 taatcttcga tcgttttctt gatcgattca gataatgttt gaggtggata cacagccatt
     8581 gaatcccctg aatggacacc agcacgctca atatgctcca tgatccctgg gatgagtact
     8641 gtttcaccgt cacaaatcgc atccacttcg cattcaccac caagcaagta acggtccact
     8701 agtactggat gttctggaga tgctttcaca gcatgttcca tgtaatcttc taaatctcgc
     8761 tggttttcaa cgatttccat cgcacgtccg cctaatacat agcttggacg aacaagaact
     8821 ggataaccaa ttctcgaagc gataaccacg gcttcttctt tacttgtagc agtatcccct
     8881 aaaggttgag gaatatccaa ctctttcagc gcttgctcga ataaatcacg attttccgca
     8941 cgatccaagt cttcgatcgt tgtccctaag atttttacac cagcagcagt caaaggttcg
     9001 gctaagttga ttgctgtctg accaccaaat tgaacgatta ctcctatcgg ctgttctagc
     9061 tcgatcacat tcatcacatc ttcgaaggtc aatggctcaa aatataattt atccgaaata
     9121 gaaaagtcag tcgaaactgt ttcaggattg ctgttcatga tgattgcttc gtatcctgcc
     9181 tgctggattg ctttgacaga atgcacagtc gcatagtcaa attcaacccc ttgtccgata
     9241 cggataggac cagatcccag tactagaatt gagggctttt ctgatcgtga actttcattt
     9301 tcatattcat aggaactata aaaataaggt gtttttgatt cgaattccgc tgcacaagtg
     9361 tcaaccatct tatatacagg aatcaaatca ttttcttttc tcatctggcg aacggcttct
     9421 tcgtttattt cccacagctc cgccactttt ttgtctgtaa aaccgttttg tttcgctgtt
     9481 ttcaatatct tgtcatccaa cggctgctgt ttcaactgct gttcgatttc tacgatatgc
     9541 aacagtttat ctaaaaagaa taaatcgatt tttgtcaaat ccgctaattc ttctatggtg
     9601 taccctcttc taatagcttc agctacataa aacaggcgat catcttgtgc tcgaaccact
     9661 ttttggatta ggtcatcgtc cgtgatgtct gccaactcag gaagttcgat atggtgtgta
     9721 ccgatttcta aagaacgcac agctttcaat aaagactctt cgatattccg accgatagcc
     9781 atcacttcac cagttgcttt catctgcgtg cctaaaagcc gttctccgtt ttcaaactta
     9841 tcaaacggcc agcgaggaat tttagctaca acataatcta atgcaggttc aaattctgca
     9901 aaagtcgttc ctgtaacagg atttttcatt tcgtctaatg ttaatccaag cgctatttta
     9961 gcagctagct tagcgatcgg atagccagtc gccttacttg ctaacgcaga tgaacgagaa
    10021 acacgcggat tgacttcaat cacataataa ttaaaactat gtggatcaag agcgagttgg
    10081 acattacagc ctccctcgat cttaagtgct cgaataatcg aaagagaagc atcacgaagc
    10141 atttgatatt catggtcaga caatgtttga ctaggggcaa atacgataga atcacctgta
    10201 tggataccca ccgggtcaaa attttccata ttgcagacaa cgattgcatt atcagccgaa
    10261 tctctcatca cttcatattc aatttcttta aaacctgcaa tacttcgttc aatcaaacat
    10321 tgggtagcgg gggaaagact taatccattt tctgatacga tacgtaattc ttcttcattt
    10381 tcacacatac ctccaccagt tccgcctaaa gtaaaggctg gacgaacgat gacaggatag
    10441 ccgattttat ttgcaaaatc tacagcttct tctactgtat tgacgatttc agactcgggg
    10501 attggctgat tcaattcttt catcaactgt ttgaatagat cacgatcttc tgcttgatcg
    10561 atcgcagaaa gctttgttcc tagaagttct atgttcaatt cttctaaaat acctgatgct
    10621 gccagctcca ttgccatatt gaggcctgtc tgtccgccta aagttggaag gagagcatct
    10681 ggacgctctt ttcgaagaat ccttgataca aattcaagtg tgatcggttc gatatatact
    10741 tgatctgcca cttctttatc cgtcatgatc gtcgcaggat tagaatttac taaaaccact
    10801 tcatatcctt cttcttttaa ggcaaggcag gcttgtgttc ctgcgtagtc aaattctgcg
    10861 gcttgaccaa tgatgatcgg accagatcca atcaccataa ttttcttgat atctgtacgt
    10921 ttcggcatct gtttactgct cctttcctgc gtccatcatt tccataaatt catcaaataa
    10981 atgtagtgca tcatgcggac caggggcagc atctggatga aactgcacac tgaaagcggg
    11041 ataatctctg tgtttgactc cttctactgt tccgtcattt acttctacat gagttacgat
    11101 gagtttttct ggatcaatcg tggcttcatc gactgcatag ccatgatttt gagaagtaaa
    11161 atcaattctt ccggtcgcta cttctcgtac cgggtgattt aatcctcgat gtccgaattt
    11221 cattttatag gtatctgcac cgttggctaa agcaaataac tggtgaccga gacaaatacc
    11281 aaaaatcggt acttttcctt ggattttttt gatcatttcg attgcttctg gcacatcttt
    11341 tggatcacca ggtccattcg tcagcatgac tccgtctggt gatagcgcta aaatcgtctc
    11401 ggcatctgtg ttatagggaa gtactgtgag gttacagttt cttttactca attctcgtaa
    11461 aatactatgt ttcaagccga agtcaatgac aatgactttc cgacctgttc ctggacttgg
    11521 ataaggtttg ttagttgaga cttgctgcac ttgattggtt gctagaacgg ttgctttcag
    11581 ctgatcaaat gcatgttcga aggaatctcc agcatcaact atactagctt tcatcgttcc
    11641 gacttcacgg attttgcgag taagggcgcg cgtatcgata cctgatattc caggaattcc
    11701 tttttgtttc aaaaatgaat ctagcgtcat ttggtttcgc cagtttgaag ctacacgtgc
    11761 atgttctttt actactactc ctttgcatgt tggagaaatc gattcataat catctctatt
    11821 taccccataa ttacccacca taggataggt aaatgtaatg atttgaccgt taaaactttg
    11881 atcagtgata gtttcttgat aaccagtcat acttgttgta aaaacgattt ctccgaagac
    11941 actagcatct gcaccaaaag cctttccttc gaaaactgtt ccatcttcta atataagcaa
    12001 acgttccata cttttattct cccttctgcc acacaagttt tccgttgaca aaagtcattt
    12061 gtgtttcgcc ttttactttc cagccgataa aaggtgtatt ctcccctttt gataaaaagt
    12121 cttctttatc gatcgtgcaa gtttgtgtaa tatcaaaaac tgctacatca gcgggggcac
    12181 caaccgttag cgttcctgca ttcaaaccaa aaatctcagc cggtttaact gccaaccaat
    12241 tgatcacttg ttccaacgtg aatcgaccag tttctacaaa atgagtatag atcagttgaa
    12301 acgctgtttc gcttcctacg ataccaaatg gtgatttcat gaaactttgg cttttttctt
    12361 ctaatccatg gggggcatgg tctgtagcga tgcaatcgat cgtaccgtca agcaagcctt
    12421 cgatcaaagc ttctctgtcc tcccgtcctc ttagcggcgg gttcattttc caaaagccga
    12481 aatcttcggg aatatcttcg tcgatcaaaa taagatgatg gggtgaaact tctgctgtta
    12541 cgtggattcc tgcttttttt gcgtctctga ttacacggac actttcttta gtagaaacat
    12601 ggcaaacatg gtaatgaaca ccagttgctt cagctagcaa cagatctcta gcaatttgag
    12661 aagactcggt tacgcttaag atcccgggaa gaccaagttc ttctgccttc ttgccagcgt
    12721 gcataacgcc gccaaataat aaagattcat cttctgtatg ggctactagg gctttattgt
    12781 tttttgcagc ttctttcata gccagataca tcgtcccagc tgtttggaca cctacaccgt
    12841 catttgtgaa agcaaaagca ccttcttcaa tcagtgcttc ttgatcaact aatttctcac
    12901 ttcgcagatt ttctgtgatt ggcgcatact gcaatacctt cacaactgca tcttttctaa
    12961 tgatgtcata tacttgtctc agcttttctg ccgtatcagg tacaggattt aaattcggca
    13021 tcgcgcatac agtagtgaaa ccgccacgag cagctgagcg agtcccagct tcgatcgtct
    13081 ccttgtatgt aaatcctggc tctctcaaat gaacatggac gtccactaaa ccaggtgtga
    13141 tcaattgtcc ctttgcatca aacacttcat caaattcggc ttctgagaat cctgtaccga
    13201 ttgctttgat tcgcccatct tctatccaaa tttctgctgg tgtcgtcata ttttttcgtg
    13261 tattgatctg accgttttta atgagtgttt tcattttttc atcctcctat aattacgctt
    13321 ttccatttag cactgcttct aagattgcca ttctgacgaa tactccattg ctcatttgct
    13381 gaacgatccg cgactgtaat ccttccacta atgaatcagc taattctaca tcacggttaa
    13441 ctggtgctgg gtgcataatg attgcatgtt tttgcaactt cttcgcacgc tcaactgtta
    13501 acccatgttc ctgatggtag ccttcttttg agaaactttc ttttccatca tggcgttcgt
    13561 gttgcacccg aagcatcatc atgacatcaa cttgatctag tagttcatcc aatggcatat
    13621 aatgtccgta cacttcgaat tcatcgtcgt accattctct aggacctgag aagaatactt
    13681 gtgcgcctag acgttttaac atctgcatat tggatttagc tacgcgagag tgagtgatat
    13741 cacctacgat ggcaactttc agaccttcaa aatgaccaaa ttcttcataa atggtcatca
    13801 aatcaagcaa gcattgggtt ggatgctgtc cgcttccgtc tcctccattg ataatcgaac
    13861 actggattgt tttactttgt atcagttcgt cataatagtt ctcatcacca tgacggataa
    13921 ccgctacgtc tacgcctaat gctgacatcg tcagtactgt atcgtatagt gtttcccctt
    13981 tttggacaga gcttgtgctt gcttcaaatt caatcacttc tagccctagt tttttctccg
    14041 ctacatcgaa gcttttatgt gtgcgagtac tattttcgaa aaagaggttt gtagcaaagt
    14101 actggcgctt ttgcggagtc caattagcac cttgcttgaa ttcctgccct ctgcggatca
    14161 agcccataac ttcttgatca gtaagtgcct caacggtcaa taaatgcttt aagctgatac
    14221 gttctgattt gatgatcata atgtttcctc cttagttttc ttcgcttcgt gaagtttctg
    14281 gtaagataag atttaaaatg atgccaagta cagttgctaa tgccattgcc gacaatgtaa
    14341 atgtgcctac ttcaaagacg agtccgccaa ttcctactac taagataact gaagcaatca
    14401 acagattttt ctttttatca aaatcgattt tgttctcgat taaaatcttc attccacttg
    14461 cggcaattac tccaaataag ataaaactga ttcctgagat gactggtcca gggatactta
    14521 aaatcaaagc gcttaatttt cctacgaatc ctaaaatgac tgcaaatact gcagctccac
    14581 cgatcacaaa cacgctatgg acacgtgtga tagccagaac accaatgttt tcaccgtaac
    14641 ttgttacagg aggacctccg acaaaggctg ccacgatttg tgctaatcca tcacctgtca
    14701 acgtcttatg aagacccggt tcttcaaaga aattacgttt agttagttta ttcaatacca
    14761 taagatggcc gatatgctct gtcatcgtca caaaagcgat gggtgccatt gttgtgattg
    14821 ctccaagata tagctttggt tcatattgta caaagggaat ctcaaagtta ggaacagcaa
    14881 accaggcagc gtctacgatt ggcttagtat ccacgattcc aaacagcaag gctacgatgt
    14941 atccgctaat aatacctagt aaaatcggaa tcaatccgag aaaacctctt agccacatgt
    15001 tgaagaaaat tgttaatcct aatgtgatca gcgctacagc aatatacttg aaatcatacg
    15061 tgccctgatt atacatagca tttgttgctg catttgccgc aagtcccaac ccgataacca
    15121 tgatgactgg accgacgacg attggaggca agattttatc cagccatgct gaaccgatct
    15181 ttttgatgat cagcgcaaca atcaaataga ctaatccagt tgtgactgct ccttgtgcaa
    15241 tcgctggata accatctgtt ttcatcaaaa gctgcatcgc tgcaatgaaa gcgaagctgc
    15301 ttcctaagta cgcaggtatc tttcctttag tagtaaataa gtacaccaat gtacctagtc
    15361 ctgaactgac tagcgcaata cctggatcga tacctactaa gatggggact aacacggttg
    15421 ctccgaacat cgtgaacaag tgttgtaaac ttaatcctac ccaatgtcct ggggttgggc
    15481 gatcgtggat atctaacacc acgtcatcat tatgaaatcc ttttttctcc gacatgtttc
    15541 tctctcctct aatcttcctc tttcaaaatc atgatgcgat cttgtccatc aagctcttgc
    15601 atctctacta aaatctcttc cgcccgagat gttggaatgt tcttcccaac ataatctgca
    15661 cggattggca attctcgatg cccacgatcg accaggactg ctaatgaaat ttttcttggt
    15721 ctgccaaaat ccattactgc gtccattgct gctcgaatcg ttcgtcctgt atacaaaaca
    15781 tcatcaatca aaataacttc ttttccttct aaggaaactg ggatgtcaga agaatgaagt
    15841 tccggttctt ctggattttc ttttttgtca tctcggtata aagtgatatc cagttctcct
    15901 acaggaatat cgatatcttc tagctgcttc aggcgttcgg caattcttga tgcaatgtag
    15961 attcctcgtg ttttgatacc taccaatacg atatcttgga tactatggtt tctctcgata
    16021 atctcataag taattcgagt caatgctcgc ttcatggtta cctgatctac tacttctttt
    16081 gcttgcattt tcattccccc tacttttttg cataaaaaaa ctcctgccct aagaggacag
    16141 gaggaatgtt tagactgagc gtatactgat acactgatag ctatactatg tcaatgagca
    16201 atctacttat ggcgcaccat acgtatcctt gctcccaccc ttcttagcct cacgggacta
    16261 aacttaaagg aattctatta agttttatgc tttcgttgtt aattactata ccgttatcta
    16321 aattaaaatg caatgttttt tcttaatttt tctaaagttt tttcaaaaac ttctggaaga
    16381 ggtgcttcaa agatcatctt ttcgtttgta gtcgggtgcg taaaacctaa catttgcgca
    16441 tggagaaact gaccattgcc tttcaaagtt ttcttcggtc cgtatactgg atctccagct
    16501 aacggataac cgatatactt catatgcaca cggatctggt gtgttcttcc ggtttctagt
    16561 tttaattcaa ccagagtaaa tccttcgaaa cgttccaata cagtaaaatg tgtgacagcc
    16621 gacttcccat cttctcttat cgcctgcatt ttccggtttt ccttcgaacg gccgattggc
    16681 gcattgatgg ttcctttttc gtgaggaatc tctccatgga ctaaagcaac atatttgcgc
    16741 aaagaggtct tatcttttaa ttgctgagct aatgattcgt gtgcctggtc atttttggca
    16801 accattagca gtccggaagt atctttgtcg attcggtgaa caatacctgg acgaataacg
    16861 ccgttgatcg tagaaagatc cttgatatgg tacatcagcg cattgaccat tgtgccatgc
    16921 gtatgacctg ctgaaggatg aacgaccatt ccttgaggtt tgtttatcac cgctacatct
    16981 tcatcttcgt aaacgatcgt caacgggata ttttctggga ccacatctaa tgtttctggt
    17041 tcggggatca agacagtaat ctcgtctcct tgttttactt tgtaatttgc tttgactggc
    17101 tgtccattga cagaaaccgc tccatttttc agccacagct gaatttgcga acgactgtaa
    17161 tcggtgaata aattagtcaa tactttatcg atcctaccag attcatggtg aatcgtcgtt
    17221 ttaagttctg tcattttttt ctttgatcct tttcatctaa aataatataa attaacatac
    17281 aaatcactcc acatacaagt gtcacatctg ctacgttaaa aatcggaaag ctcataaaat
    17341 ctgtctggaa catatctact acatagccaa gacgaatacg gtcgataaaa ttgccaatcg
    17401 caccagctag aatcaaactc aatccaatca tgaaccagcg attacctttt tcacgatttt
    17461 taatcatcaa tgtgagaatc acaacgactg caatgagtgt cactatagta aagaaccaca
    17521 tcttcccttc tagcatactc catgcggctc cagtgtttcg aatatgattc agtgacaaaa
    17581 tacctggtat aagatttttc gtctctccaa gcgctagatt atcagtgatc caccatttga
    17641 ccaactgatc cactcctact agcaaagcgc tgaatatcca ataaataatt aacaaaaaat
    17701 caatcctttt ctatttgttt ataaatatca cgaggtcgta cgatcccgag cagattacca
    17761 tcgggattcc catctttagt gataagtacg gcttccaaag tcccttgctc acgaaacatc
    17821 gcttcaacct cgtaaatatg tgttttagct ggaacaaaat gataatttgt gtactttccg
    17881 ttttggatga tcaaatccaa cgctcgttta tttgttaaat caaccggacc tttttggctt
    17941 tcttttgcta gccaaaaccc gatattacgt aaagtaatca atgctacaaa ttttccttta
    18001 ttgtataacg gaaattgtga ataccttttt tctgctacta tctttaacag ttcaagtaac
    18061 ggaagatctt gttcaaaacc tgttacacgt tttgcaaatc gaggcagcac ggtttcaggc
    18121 tgaatcagtt cttgttcgat cagctggatt cgcttgactg tccaatcatt tggctctgca
    18181 atgacaaaat cgactgcgat ccgatcatgg acgatcgcat tccttaactg agcaagctgt
    18241 aaaagatcat cttcgtattt tctgatcatt aattgttttc tttgagctag gcgtctgaca
    18301 agttcggtaa atcccatatt tcgtgcattt cccatctcgt ctctcatcca tttttcgatt
    18361 cgattgaaac tgattaaaaa aagatcagag tttgccataa ttttcctcct tgatcaaata
    18421 tgcccggttt tttatataga aaaagaacgc aatcaacaca ataactgcaa aaaaactgaa
    18481 aaataaattt tgtaggaaaa cggcccccaa cccagttgct agaaataaaa acggatagat
    18541 ttgaagaatc aagtaattca ttgtgatcac ataagcaggc tttgcttctt tcactgtata
    18601 aacggggctt tttagccaat aaaaggtgac ctgcatcgta aagggcactt ccagatcaag
    18661 cgttatcttt tgttcatgac tgagaacact gcgtttttca ttgttgattc ttagctgaat
    18721 cgagctaccc ataccgtaaa aaccggtttt tcttataaat gtcgttttca tcataccctc
    18781 ctattatgct ttagtatagc tcaaaataca ataaagaaaa agaatgatcc tagtgtaaac
    18841 aaaattaatt ccctatcgtc taaaaaaaga agctgtagtc aaaatacagc tccttcgatg
    18901 gtagattata atcaagctta aaacaatccc aacacttctc cgtcatttgt cacgtccata
    18961 ttcaatgcag caggtttttt aggcaaacca ggcatcgtca taacatctcc agtcaaggct
    19021 actaaaaatc ctgcccctaa ttttgggatg atttcgcgga tcgtgatggt gaaatcttcc
    19081 ggtgcaccta gcagtgaagg atcatcagaa aatgaatact gtgtttttgc catacaaatc
    19141 ggcagtttgt cccatccatt cttcgtaaac tcttctattt gtttttgcgc ttttttgctg
    19201 aaaacaacac catttcctcc gtaaattttc ttgacgattg tttctgtctt ttcttgtatc
    19261 gtttcttcta ggcggtataa tggcttgtaa ttagcttctt ttctatcaat caatcgtact
    19321 acagcttttg ctaaatcaac gccgccttct gctccatctg cccatacact cgctctcttg
    19381 gcaagaatcc cctgattttc acacaagtgc tccaacagtg tgagttcatt gtctgtatct
    19441 gttacgaatt cattgattgc gacgatcaca ggtagctgat attgttccat attacgtata
    19501 tggcgcttta aatttgcaaa acctactttc aaagcatcaa gattctcatt tttaagttca
    19561 tcttttttca ttccgccatg cattttcaat gcacggacag tggcgacaat caccacagca
    19621 tccggcgctt ttttcaagtt aggtactttg atatctaaaa atttctctcc gccaagatct
    19681 gcaccaaatc ctgcctctgt gacaacgtaa tctgctaatc tcaatgctgt cttggtagct
    19741 aaaatactat tgcagccatg agcgatattg gcaaacggtc ccccgtggac aaaagctggt
    19801 gttccgtaaa ttgtttgtac aagattcggc ttgattgcat ctttcagcag taatgccaga
    19861 gcgccttctg ctttcaagtc tccagcagtc acaggctgac ggtcaaatgt atagccgaca
    19921 acgatccttg caagacgagc ctttaaatct tcaaggtctg ccgcaagaca caagatagcc
    19981 atgatttcgc tggcaactgt gatatcaaac ccatcttctc ttggaacacc ttggattggc
    20041 ccacccaagc caacaattac tttacgcagt tcacgatcat tgagatcgac tacccgtttc
    20101 caaatcactc ggcgggcatc gatgttcaat tcatttcctt gatgaatatg attatctaaa
    20161 agagcagata atgcattatt agctgttgtg atagcatgca tgtcaccagt aaaatgcaag
    20221 ttgatatctt ccataggcaa tacctgtgca tatcctccgc ctgcagcacc acctttgatt
    20281 cccatcacag gaccaagtga gggttctcgc aatgcaataa cagatttttt attgatttta
    20341 ttgagcgcgt ctcctaaccc tacagtgatc gttgactttc cttcgccagc tggtgttgga
    20401 ttgatggaag taactaagat caaatgcccc tcagcgttat cctttgatcg attgattcca
    20461 gaaaaattga ttttcgcctt atatttccca tacagttcca aatcgtcttc cttaagatct
    20521 aatttactag ccacttcaac aatcggttct agctctgttt cttgtgaaat ttgcagatca
    20581 ttcttcattt gattacccct tttcacgaac tttattcaac aaaatatctt ctttgttaag
    20641 atatgccaat tatacctttt tttattcaga aaaaaaacat aaaattacag gtttttaatt
    20701 tatttgacgt acttataaat actctttata atgaaggcta tgatcagact ttagaaaggt
    20761 cgtgagtgct ttgaccacag gaattgtaaa atggtttgac aacaaaaaag gatacggctt
    20821 tatcagttat gatgacacag aagaaatttt tgtacatttt actgcgattg aagaagaggg
    20881 attcaaaact ttggaagaaa atcaagtggt cgaatttgag atcatcgaag ggaatcgagg
    20941 aacacaagct gcccatgtca agaaaggcaa cgttcagact accgatacta gtatgcatga
    21001 atagataaac aaatagagtg agacgctaaa cgggatgaac cgtacgtctc actcttttct
    21061 tttcctgtaa aaattcgttt ttttaggttc tgatttttaa aattagcttt ttcttttttt
    21121 cgtataagga taaggaattg attctgattt gggtccgttt ttttcaaaat gatcaaaaag
    21181 gactacttga tctttttttc gcatcatgaa aacagatggg gctttctcat cttgcaacat
    21241 catttgcacc ccagtattag ttggcgtcaa agatcgaatc tgtccgacag atatttctcg
    21301 gtctttccaa aaagcagcat aacgtataat cacagagttt gattttaaaa taaaagaacg
    21361 ccgcaaacct agaaatagaa aaacaagaaa aatacctaaa acaaaattgc ttttccaata
    21421 aggacctgtg ttttctaaag aaagaatcag actaaaaaac agaatgatca aggtcaatga
    21481 ccaatagatg atcgtatgtg ccagttcagg ctgccatcga atattttttt tcattctcta
    21541 acctctcacc gattcagtaa tgatataatc ttaccataac attagtttga acaaaaagga
    21601 gaatctcttt ttatgttaaa agtatacatt gatgcctcta caaaaggcaa ccctggtcct
    21661 agtggaggtg gaatcttgat tgtctatcaa ggtaaacaag aacagctatc tatcccgctt
    21721 tctataggga caaaccatca agcagagttc gaagtctttt taaaaacttt agaatttcta
    21781 aagaaaaacg acttacagaa tgaaacgatt ttctgttttt cagacagcaa aacactagtt
    21841 tctacggtcg acaaaaacgc aacgaagaac gagctcttcc ttccctacct tcaaagaatc
    21901 caagaacttc tatccgaatt ttctttattg atcctgcaat ggttgcccga aaacaaaaat
    21961 aaaggagcag ataatcttgc acgtcaggct ctccataaac aattaaaaga aaaaaagact
    22021 ctttaaatta aaaactttaa ggagtctttt tatagtttct catttaatat aaaagataat
    22081 tgtgatcaaa cgtaatttcc aattggtaat ctccgatttt ttcttctatt tgactacgta
    22141 agattctttc tagttctgta tcaacaaact ggaatttctc agggaccact acatcaaatt
    22201 gcagcgtttt tccttgatga attactctaa aatcatgaat attaagccct gtacctgttt
    22261 caagaagaat ttgctttaac tgccgcaaga tattatagta tttttcgtta tcaacaggca
    22321 ttggatccaa gtgacagaca agttccacat ccaaagactt tttaaagtct ttttctatca
    22381 gatcaataat cttatgagcc acattcaaat tcattgattc atctacttcg atgtggactg
    22441 atgcaaagcg tttattgggt ccatagttat gcaccaataa atcatgatag ccaagtatat
    22501 catcgcaagc atttaaatgc tcttccattt cttcaatctc tgctggcgtt gggcgacttc
    22561 ctaatagttc gtatacaaaa tttcgaagca tcgtcaatcc actataaagg atatataatg
    22621 ctaaagcaaa acctatatat ccatcaatac gccatccagt tacccattcg attgctgctg
    22681 aaagcaatac agccagtgta gtaaagacat cattataact atctgttgct gtagctctca
    22741 atgtttcaga atcaatggat tgcgcaataa cctgatacat tttgccttgt gcaaatttca
    22801 aaaagatgga aatgattagg acaaaaaaga cgatgggtgt taaagagaca ttttctggat
    22861 ggatgatttt ttcagcagaa gactctaaaa attgaaatcc tacataagta atgatgatcg
    22921 aaacaaataa cccactgata tattcgaagc gttcgtgtcc ataaggatgt tcctgatctg
    22981 ctggctttgc agcaatttta aatccgatca aagtcaatat ggatgaagca gtatctgata
    23041 gactgttcac tgcatcagcc ataatggaga cacttcctga aaaaagcccg atcattagct
    23101 tagagacaaa caagatcaga ttcgtaacca atcctaagat acccgctagt actccttttt
    23161 ttgtccgctg ttgcggtatt tgtttctttt tttcttcttg tttcttagcc aagtttttta
    23221 ccccttctag tttgcttgtt gctcaggtaa aaagatggag aggacgattg ttttcctctc
    23281 ctctcttcct ttttctatct atcgtgcgtc ctattactat taaaagatgg tcattattct
    23341 ggtttcaacg gtgttgctgc aaataacgct tttgctagta atggtgttat gattcccgca
    23401 cctattgctt ctggtatccc attgattgct gcaacccctg ctaaggtttt aaataaaaga
    23461 gcagagtcta caccataggc atctgccgtt gcacctgtat aaaataatcc catgaatcct
    23521 aacactaaga ctgtattgac caatgaaccc agtacccctg caaaggctga gctgatcgtt
    23581 attgatttat ttttttgata aatccagtgg aaaaccaagc ctgctactaa gccaacaagt
    23641 actctgggaa ctaccgagat aatcggattc gtgaacacta atgtatcaaa tggcgttgtt
    23701 ggcatggcat aggcacgaac aattgtagcg attccccaaa acaagccaat caccatgcca
    23761 tcttttgggc ctaatactac tgcagcaata attactgtga tatggataat tgttaaacta
    23821 atgaatccta atggaataaa ccccagccaa ggaaccatcg cttgtacgat gatgattgct
    23881 aacaagatcg cacgtaagac tagtcgaaag gtcttatttc tactattcat tttttcaccc
    23941 ctttttattt atactaatcg taaaaatttc tgtcactttc gtcaactaaa gaccatccga
    24001 atccgaccat ttgattagat gcgccatcca attgaaaaaa gtatgagggc aagacttgtt
    24061 tgtcttcgcc cccataatca tgtttcgttc aatgtttgaa cttttgtttt tctgtcaaac
    24121 gtaaacgccc tattgttgcg caacccattc tttcgcagct ttaagtgcat ctggaatacc
    24181 agcaggattt ttcccgccag cttgtgccat gtctggacgt ccaccaccgc caccgcctac
    24241 tttcggtgcg attgctttaa tcaagtcgcc agcttttagt ccagcttcat ttgattcttt
    24301 cgtcattgcc gctagcagac tgacttttcc ttcttgttcg tttgctaaaa caagaatatc
    24361 tgaaatattt ttttgtttcc attggtcagc taattgacgc agctgattca tatctttcac
    24421 ttttacttgt gctgcaatga ttgtttttcc attgatcgtt tctggatctt tgaatacatc
    24481 accagcttgt tgattcgcta acttgctagc taattgttca ttttcctttt gtagctctct
    24541 tacttgctgt tgcaattgtt ccgcttttga aacaacttct ttcaattgag gtgatttaac
    24601 aattgttgct acttgtttta gttgtttttc ttcttcttca agtagttcgt acgcttcttt
    24661 acttgttaca gcctcgattc gtcgcacgcc tgcaccaatt cctgattcag aaacgatttt
    24721 gaagattccg atgttttctg tatttgctac atgtgtgcct ccgcacagtt cgattgacca
    24781 gccgccaata tttactactc gaacgtcatg tccgtatttt tcaccaaaca aagccattgc
    24841 acccatgttt ttggctgtat cgatatctgt ttcaattgtt tcaactggga tagcttccca
    24901 gattttttcg ttgacgattc tttccatttc agctaattca tctgaagtga tttgaccaaa
    24961 gtgggtaaag tcgaatcgta aatgtccagg agcgactaaa gaaccagctt gatttgcatg
    25021 ctcgccaagt acttctttca atgccttgtg cagtagatgg gttgctgtat ggtttttgat
    25081 gatccgattg cgcatcgatt gatcgatcaa tagatgatag gtttgtcctt cactcattgg
    25141 tgcttttact tctacggtgt gcataaattg accattaggc gctttttgaa catctgtaac
    25201 aactgctacg atttcgccta cttcattcat gatccatcct tgatccgcta cttgcccacc
    25261 catttctgca tagaaaggtg tttgatcaaa gatcatttga gcttcacctt ctgcgacttc
    25321 attcaaaaga gactcacctt taacgatgac caataattga ctatctgatt cttgttctgt
    25381 gtatccaatg aatttacttt ctactttgat atctgtcaat aaagcagatt gtacccccat
    25441 tgatttttca gtactgcggg cagagcgagc acgttcgcgt tgtgcatcca tttctttttc
    25501 aaaaccagca tgatcaactt tcagtccttc atcttctgcc acctcttccg ttaattctac
    25561 cgggaagcca tatgtgtcgt atagtttgaa gatgtctttt cctgctagag tcgtcccgtt
    25621 ttcgtttttt acttcttgga tcacttgatt taagatttcc aaaccttcat tgattgtttc
    25681 attgaaacgt tcttcttctg tacggataac tttttcaata aattcttttt gttgaagtac
    25741 ttcaggataa taacttacca tgatttcccc aacaacaggg actaaacgat ataagaatgc
    25801 ttgttcaata cctaattttt tcccatgcat gacagcacga cgaagcaaac ggcgtaagac
    25861 ataccctctc ccttcattcg atggcaatgc accgtcgcca atagcaaatg aaagggcgcg
    25921 aatatgatct gcgattactt tgtaagaaat atctgttact gggttttcac catattttac
    25981 ttgtttgctt agcttttcta cggcgtggat aataggcata aacaagtctg tctcaaagtt
    26041 cgttgacgca tcttgaacga ttgagaccat gcgttccaat cccatccccg tatcaatgtt
    26101 tttatgagga agtggttcaa atgtgttatc aggcttatgg ttgaattctg aaaatactaa
    26161 gttccagatt tctaaataac gttcattttc tcctcctgga tagttttcag gatcgtcttc
    26221 tgctaaatcg ttataagctt ctccacggtc atagaaaatt tccgtatccg gaccacatgg
    26281 gcctgcaccg atatcccaga agttgtcttc tacatcaata atgtgatcta gtggcaggcc
    26341 aacttcttca tgccagatgc gttttgcttc tgtatctttt ggataaactg ttacataaag
    26401 tttttctgga tcgaatgcca tccattttgg atcagtcaaa aattcccatg cccagtggat
    26461 ggcttcattt ttgaaatagt caccaatcga aaaattaccc agcatctcaa acatcgtatg
    26521 gtgccgtgct gttttaccga cattttcgat atcatttgtt cgaatagatt tttgggcatt
    26581 tgtgattctt ggattttctg gcacaactga accatcaaaa tattttttca atgttgcaac
    26641 accagagttg atccacaata aggttggatc gttcacgggg atcaaagacg cactaggttc
    26701 aatcgtatgt cctttagatt ggaagaaatc aagaaacatt tgtcgaactt gtgcactact
    26761 taattgtttc atgtcattac ctgctttcta taaattaaat acaaaaaaac accatcacag
    26821 ccaaggacga aaactcgcgg taccaccttg attgcaatga tgtgtaatca ttacctctta
    26881 aactcgataa cgctgagctg cgtcggtatt tctaccaaaa tagaaaaagg gagcaatttg
    26941 attagtgact attctttttt cagccaagaa agaattttct gtgagtctta aaaaacaaat
    27001 catatccttt tcgtacttaa ttagtatacg cattctattg atcactgtca atatctcaat
    27061 ttttattttc atttcctttt ggtcatactc cacgattttt ggtacgataa gaataaagga
    27121 atcaatacat ctctgctatt catgacaagg aggaatatga tgaaaaaaat agttggagcg
    27181 gatgaatgga tacgcgcagc tagctgcttt ttgagatatc aagtttttgt attagaacaa
    27241 gggattcctg cagaactaga attcgacgga aaagatatcc cgcaacaaac ctattatcta
    27301 tttcttgatc aaaaaagacc agtagctact ttgcgttatg aaaagaaaac acctacttgc
    27361 ttcaagccgg aacgattttg cgtagcaaaa gaataccgag gaaaagggtt aggcggtcag
    27421 ttgcttgaag ctgctgaaaa acgggcggtt tcagaaggtt gtcagactag ttatgtagta
    27481 gctgaaatga cggctgtaga tttttatgaa aaacaagggt atcatacttg cacagaacct
    27541 tttattgaag atgaagtact ttgtatcgga atgaaaaaaa gtctagctta aaaacaagag
    27601 attgtgacac gccttttgtc acaacctctt gttttttatt tatgtgaatt tttcttattt
    27661 ttacgagcag tacggctttg ctgtctgcgt tcgattttgc gttctttttt atttttttct
    27721 gcaattgccc aatcgatttt tttcttataa ccaggcttga tctttttctt tttcttcttc
    27781 acaagaccaa tcagcgtggg atctaataca tcttttgatt tttctcgttt ggcacgtcta
    27841 ttacgatcgt atgttttgac gatttccccg tttttgattt cttttggttc aaatgagacg
    27901 cccaattttt ctatcgcatc aatggcttgc tcatcatttg gcgaatataa cgtaatggcc
    27961 gttcctttta agccattacg tccagtacgt ccgacacgat ggataaagaa gtctagatct
    28021 tctggaattt ctgcattaat aacatgagag acaccttcga tatcgatccc tctagcagct
    28081 aaatcagtcg ctacaacata ttgatactcc agattctgta cttgtcgcat cactcgtttt
    28141 ctctctcttg gggtgatgtc tccatgaatc tttgctactt tcaagccttg gtttttcaag
    28201 taatcggcaa tttcatccac atgctgtttt gtattggcaa atacgattgc taaataagga
    28261 tgaccaattg tcagcagttg ataaatcatt tgattctcat ctttaccttt tgttgaaatc
    28321 agccaatttt caatgtcttc agaaataact gcttttggtt tgatttcttc aatgattgga
    28381 ttttccatgt attttcgtaa gaatggacga agtttttctg gaatagtggc agaaaaaact
    28441 aaaaactgca gcttttctgg taatcgactt gcaatttggt ctacttcatt taaaaaaccc
    28501 atatccaatg tcatatccgc ttcatcgaca acaaatgcaa atgcggtgtg aatcttcagc
    28561 gcttgttcat tcatcatgtc taatattcta ccaggcgtgc ctactacaac ctgtggctgt
    28621 tggtgatgca gacgatttaa ttgacgctgt ttgtctgtac cgccgacaaa attcgagaca
    28681 cggatctccg gtgtagaaaa tttagcgatt tgtgtagctg cttcatagat ctgtgcagct
    28741 agttccctac ttggagctgt aataacaact tgtacttcct ctttttctgc attgattttt
    28801 tcaaacaaag gcaacaaaaa cgtatgtgtt tttcctgtac cagtttgaga ttgcccaatg
    28861 atattttttc cttttgcaat taaaggaatc aaacgttcct ggacctctgt gggctgtttg
    28921 aagccctttg cggttaacgc ttcattgata aacggtttga agcggaatat atcaaaatta
    28981 ttcattcgtg cacctcttct ctttaaatta tcacgacttt ggcattataa cacagacaaa
    29041 gcgtttttgc tcagctaatt tcgagaatca tcatcctttg tttggccaat cgtgctaaca
    29101 gtatatgtgt gactagcttt ttcataaaac agaatccgtt tttttctcaa aaatgatagc
    29161 aagatattta aaataaaaat accttgtagt aacaagacac cgagagaaat gaatactgca
    29221 ctcatctgca acaccgtatt cgttgtcgaa ttcatgattt gctgaagcaa ctgccccaac
    29281 cagcttaaac cataaaaaag aaagtacaga tacccgtagc ggatcatcaa tgcttttaaa
    29341 gaaattcgtt cgcggtcttc ttccaccaaa cggatacgca caattttttt gccaagtgtc
    29401 catccattgg ttataaacgg tacaatcata aagtataccc ctacttctaa taaaagccac
    29461 cagatatgag aagtaactgc ccctgaatcg aacgcaattt taaagaaaat cgccgctacc
    29521 aaattaataa gagataaaaa tgtccagtcg atcaaataag cgaccaagcg tcgagtcaat
    29581 gagacagtct ttcctttttc ataagaaagt tcatccattc gtcttcttgt aggaagcata
    29641 aatgtaaata acggcgtaac gacaaaacca atgattccac ccaatgtatt tgtcactaaa
    29701 tcattcacat caaataagcg gtatggtctt gggtagataa aataaagtcc acttagctgc
    29761 gtcaattcaa aaaatagaga aaggcagaaa ctagcaatca tcgttttcat aaaagaaagc
    29821 cggaaataat atcttaaata aatgccaaac ggtatgagta ataaaacatt aaaagctggt
    29881 tccaaaaata cactctgctt cattgccggc aggtaggtac taggttcaga caagaccaat
    29941 accgtgttgt ctctgaaatg ttgccatgaa gcaaataaat gcagctccat ctttggccct
    30001 gtcatttggg caaccgtctc ctttgccgga agtggtaaga tcaccaaaaa atacgcacac
    30061 aataaataaa aaacgaaaga atacaaaata actgcccttg ttactagaaa tgttccatac
    30121 tttcgatatt cataaataaa aaaaacagat gagatcgcta aggctaaaaa tggaaaaaca
    30181 atcagcgcaa aacgaatcgg ttcgatataa cttgccatat gactcctcct tgattctttg
    30241 tatctctctt atcttagcag tcctttgctg tttcaagcaa gtaacgaggc tattatttct
    30301 catttctttc aaagtaaagt aagataaaca caaagggggt gtcgagatgc tgaatatgta
    30361 ctttgttttt ggcgtaccta tttttttact gttcctttat gctacgatcg cttatgtaag
    30421 aaaaagaact acaattcatt atttaggatt tattctcctg attatttcgg gtttcatgct
    30481 agtcttcaat cttcagactt ggcagcaagc acttcttgaa atggataaaa tgactccaca
    30541 tgctttgtct aaagtgcttg gctaccctgt ctatctgatt tggcttccca ttttcatttc
    30601 tggttgcttg gttttattaa atatttatcg cggcgtacgc cgaatagttc agttacgcaa
    30661 atcaaagtaa aagacagaaa tcggttgagc ccgatttctg tcttttactt tgctatttca
    30721 tcgtagacaa aacgacattt acgtgatcaa aattaacgag tacttttgac atttcttcca
    30781 cgtactcctc atttaaataa aatattttgt ttggcagaga agtgcagttc taataaaatt
    30841 cgaatgtttt agctatctac gttttaaata gagataaatc gggataccag caagtgtcaa
    30901 tactatcccc atcgaagcta aaaaggtctg agtgataagc gtgcttgata cgataaaagt
    30961 ccctccaatg attgctacta gtggaataaa cggatacatt ggaactttgt atggtcgaaa
    31021 caaatcaggt tcttttttac gaagaagaat gacaccaaca aagaccatcg tataaaaaat
    31081 ccaaatgaca aagatcagca tatccgttag tgtatcaaaa ccaccgatca tcatcatgcc
    31141 aatagcgatg actagctcta agatacctgc ggctacagga actttagttt tatcatgaag
    31201 tttagcaaag agcttgctaa aaggcaggtt gttttctttt gccataacat aagggagacg
    31261 cattccagta agggtatagc cattgatggt tccataaaca gaaatcaaga taccaactgt
    31321 gaccagtctt ccaccgaagc cgccaaaaat catttttgca acgtcacttg ccgcattgct
    31381 gtttcctgcg actccgtcga tagatgcggt tcttaagaac accgcattta ctaataaata
    31441 aacgatcatg attccgatga ttcctaaaga aattgctttt ggcaaatctt tcgccggctt
    31501 tttcaattct cccgaaatat ttcctacgtg tatccaaccg tcgtatgcga acatcgttgc
    31561 tagcaagccc gctcccaagg ctgagaaaaa tgaaagattt tctcctgctt ggatcggaaa
    31621 cagttggaag tctactcctt cttgtcggaa caaaccgaaa atgacgatca caaacaaagg
    31681 aataagcttg cagacaagcg taatcgactg aaaagcccct ccagctttag aacctaaaaa
    31741 attgatcaac aggatcgata cagcagctgt aacagctacg ggaacaatca ttgactggga
    31801 aagaccaaat agattgacga actgtgtacc gaaaatgatc gacaaggctg ctacatttgc
    31861 tggaaaataa atcacgactt gcgcccagcc caataaaaaa gctgctgtat ttccgtaaat
    31921 ccgttcgata tatttaatca tccctcctgt ttctggaata gcagctgcca gttcagctcc
    31981 tgttagtcct gcacagacag aaatcatacc accgagaaac caagaaaaca tatgcaaact
    32041 ggcggatcct gtaacttctg ctacgcttgc ggctttaaaa aatacccctg caccgatcac
    32101 tgtgcccata acagtcgata aagcagtaaa aaatcccatc gtacgtttta attcattttc
    32161 tatttttact tcttttactg gcgtggcttg atattcttcc atcccttgtc ccctttcata
    32221 ccatagccaa tcccaaaagt ataaaaaact ttttggatgt ggttcttgtt ttataccgtc
    32281 tctaccaatt tttctttcag tttttccaac atatcctttg tcatcacatc taagtcgtat
    32341 ttcggcgaaa agccccattc ctcttgcgca caagaaacat ctagtgaatt tggccaagat
    32401 tctgctattg actgacgtac aggatccaca tcataatcca tttcaaaatc tggtatgatt
    32461 ttttgaatag atgctttgat ctcttccggg tcaaaagaca tcgccgatat attgaaggca
    32521 tttcgatgaa ccaatcgatc aggatctgca ttcatgagtt ttataatggc atcgatcgca
    32581 tctggcatat acatcatatc cattgatgta ccttgatcaa tgaaactagt gtactttcct
    32641 tctttgattg ctgaataata aatatcgact gcgtagtctg tcgtaccgcc tcctggcaag
    32701 gttgcataag aaatcaatcc agggaaacgg acaccacgag tatctacgcc atatttcaca
    32761 taataataat cacatagtag ttctccagct accttcgtta ccccatacat ggttgtagga
    32821 cgctgaagag tatcttgtgg ggtatgatct tttggagtat ttggaccaaa cgcgccgatt
    32881 gaacttggcg taaaaaattt cagctggaat tctctagcga cttccaatgc attgaccagc
    32941 ccagtcacgt tcaaattcca ggctaattgt ggttttgctt ctgcaacagc tgacaaaaga
    33001 gcagccaaat gaatcaatgt gtccacttga tattgttctg ctatgctgcg cattttttcg
    33061 taatccatta catctaggat ctcaaagata tcgtttttct caatgacttc aggcatgcgt
    33121 atatctgtcg caatgacatt ttcactgcct agttcttgac gtagccgtgt gatcaactct
    33181 gaaccaattt gtcctaaaca tcctgtcacc aatacttttt tcatgatgat cctccctgat
    33241 cttttttact actatcttca gatgattaac aatatatgcg tgaacatgtt ctctaatttt
    33301 aaatagacga aaaaactaaa tttagttaaa taatttccat ttcttttcct attttttgat
    33361 aaactgctac tgcttcatca agcatttccc tcgtatgttc cgcagtcggc atatttctga
    33421 tcctgcctgt cccaagaggc acagttggat aaacgattgg tttagcataa atcccatgtt
    33481 cgatcagctt cttagagaaa gtctgagtca ctttttcgtc tcccaaaatg actggagtaa
    33541 taggtgtttc agacataccg atgttatagc ctactttttt caattcttct ttaaaataat
    33601 tagcattttc ccaaactttt tcgacaagtt ccggatgttc ttgcatcaaa gtaatcgaag
    33661 ccaatgcagc tgcagctgca cctggagtta gcgaagtaga aaataggaat ggccgacttc
    33721 tagctttcaa ccagtcgatt agtgttttcg atccagctac ataaccccca acaacaccta
    33781 tagctttcga taacgtgccc atttgcatat cgattttgtc gcttaatcca aaatgcttga
    33841 cggttcctgc accttttcca gttacgcctg agccgtgcgc atcatcgacg taggtgatca
    33901 gtccatattt ttcaacaatc ggaataattt ccggcaatcg tgcaatgtct ccatccatgg
    33961 agaaaacacc atctgtgata tacatgattt ttttatattt cttactttct atcgcttcct
    34021 ttgctttttt ctcaaggtct ttcatatctt gatgtttaat tcggatgatt tttgctccgg
    34081 ataagcggca accgtcaata atagatgcat ggtttaattc atccgataag atagcatctt
    34141 cttttgtcat tactgcagag atagcgccca tattgcagtt gaatccagat tgaaaggcga
    34201 ttgctgcttc tgtccctttg aattctgcga ttttttcttc taattgctga tggattttca
    34261 gcgaaccatt gatcgttcgg actgctcctg ctcctacacc ataagtttcg gttgcttcaa
    34321 tacatgcttt tttcaattct tcgcgattgg caaatccaag ataattgttg gatgctagat
    34381 tgatcatctt ttttccgtct acgatgatac aagcaccatt ttcactttct agtatgtcga
    34441 tcgtattgta taaccccttt tctttcagtt gatccaattc tttctctaaa tacattgtta
    34501 gttctttgga agacattgtc tccacctcca tattcatctg tcttgcagaa cataccaaac
    34561 atatatcgtg tcattcatct acaaagcaag tatgctatat ttttgataac gcttacactg
    34621 attatgagaa ttatttaacc acatttttta tttacagtat ctttttactt tcaaatgact
    34681 tatatagtat gaacaattac cttttagata atgatctatt ttactctacc tgggcagata
    34741 aatacaacac aaccattgat agaagccctt tcgttaaaat caattgtatt ctgaatattt
    34801 aatttattta ttgcatagac caataaaaat acataaaatt tccatcttcg tttatcagca
    34861 atttttaatt ttactctctg aatatttctt aaaagtttta cttgttgaat tcgaaaaaag
    34921 gactgtgaca aaagtcttgt cacagtccta ttcttccgaa
//
LOCUS       DAFLWQ010000027        34218 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.028, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000027 DAFLWQ010000000
VERSION     DAFLWQ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34218
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.028"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            128..769
                     /locus_tag="L1V16_001238"
     CDS             128..769
                     /locus_tag="L1V16_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBN1275587.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            788..1423
                     /locus_tag="L1V16_001239"
     CDS             788..1423
                     /locus_tag="L1V16_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBN1275588.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            1441..2256
                     /locus_tag="L1V16_001240"
     CDS             1441..2256
                     /locus_tag="L1V16_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1275589.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            2575..4011
                     /locus_tag="L1V16_001241"
     CDS             2575..4011
                     /locus_tag="L1V16_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1275590.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            4200..6647
                     /locus_tag="L1V16_001242"
     CDS             4200..6647
                     /locus_tag="L1V16_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBN1275591.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            6877..7944
                     /gene="rlmN"
                     /locus_tag="L1V16_001243"
     CDS             6877..7944
                     /gene="rlmN"
                     /locus_tag="L1V16_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBN1275592.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(8137..9240)
                     /locus_tag="L1V16_001244"
     CDS             complement(8137..9240)
                     /locus_tag="L1V16_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBN1275593.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            9792..10340
                     /gene="aac(6')"
                     /locus_tag="L1V16_001245"
     CDS             9792..10340
                     /gene="aac(6')"
                     /locus_tag="L1V16_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBN1275594.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            10886..12547
                     /locus_tag="L1V16_001246"
     CDS             10886..12547
                     /locus_tag="L1V16_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1275595.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(12617..12964)
                     /locus_tag="L1V16_001247"
     CDS             complement(12617..12964)
                     /locus_tag="L1V16_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HBN1275596.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            13048..13989
                     /locus_tag="L1V16_001248"
     CDS             13048..13989
                     /locus_tag="L1V16_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1275597.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            13990..15033
                     /locus_tag="L1V16_001249"
     CDS             13990..15033
                     /locus_tag="L1V16_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1275598.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            15039..16109
                     /locus_tag="L1V16_001250"
     CDS             15039..16109
                     /locus_tag="L1V16_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1275599.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            16099..17052
                     /locus_tag="L1V16_001251"
     CDS             16099..17052
                     /locus_tag="L1V16_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1275600.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            17064..18074
                     /locus_tag="L1V16_001252"
     CDS             17064..18074
                     /locus_tag="L1V16_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1275601.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(18359..19180)
                     /locus_tag="L1V16_001253"
     CDS             complement(18359..19180)
                     /locus_tag="L1V16_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBN1275602.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(19277..19555)
                     /locus_tag="L1V16_001254"
     CDS             complement(19277..19555)
                     /locus_tag="L1V16_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275603.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            19823..21832
                     /gene="metG"
                     /locus_tag="L1V16_001255"
     CDS             19823..21832
                     /gene="metG"
                     /locus_tag="L1V16_001255"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBN1275604.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(22311..22898)
                     /locus_tag="L1V16_001256"
     CDS             complement(22311..22898)
                     /locus_tag="L1V16_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275605.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            23073..24395
                     /locus_tag="L1V16_001257"
     CDS             23073..24395
                     /locus_tag="L1V16_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1275606.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            24550..25326
                     /locus_tag="L1V16_001258"
     CDS             24550..25326
                     /locus_tag="L1V16_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBN1275607.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            25319..25888
                     /gene="rnmV"
                     /locus_tag="L1V16_001259"
     CDS             25319..25888
                     /gene="rnmV"
                     /locus_tag="L1V16_001259"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBN1275608.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            25881..26765
                     /gene="rsmA"
                     /locus_tag="L1V16_001260"
     CDS             25881..26765
                     /gene="rsmA"
                     /locus_tag="L1V16_001260"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBN1275609.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            27216..27845
                     /locus_tag="L1V16_001261"
     CDS             27216..27845
                     /locus_tag="L1V16_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275610.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(27969..29078)
                     /gene="ugpC"
                     /locus_tag="L1V16_001262"
     CDS             complement(27969..29078)
                     /gene="ugpC"
                     /locus_tag="L1V16_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBN1275611.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            29287..29709
                     /gene="mgsA"
                     /locus_tag="L1V16_001263"
     CDS             29287..29709
                     /gene="mgsA"
                     /locus_tag="L1V16_001263"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBN1275612.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            30032..30568
                     /locus_tag="L1V16_001264"
     CDS             30032..30568
                     /locus_tag="L1V16_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBN1275613.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(30608..32371)
                     /locus_tag="L1V16_001265"
     CDS             complement(30608..32371)
                     /locus_tag="L1V16_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1275614.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(32374..34089)
                     /locus_tag="L1V16_001266"
     CDS             complement(32374..34089)
                     /locus_tag="L1V16_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1275615.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
BASE COUNT        11152 a         6117 c         7085 g         9864 t
ORIGIN      
        1 atctgaacgg caacgactgt gtgaggtttt ttctgcaagg aaaaaataaa cagaggtgga
       61 accacgtata atacgtcctc ttggcatttg ccaagaggat ttttttattt taaaggagga
      121 aaagaagatg gagtatttga ttgaagttat gccgcaatta ttagtaggag cactcacaac
      181 attgaaatta tttttattta ccttgattgg ctcattacca ttagggattg ttttagcatt
      241 aggattgtct ttgcatttta agccgctacg ctacttgctt caaacatatg tatgggttat
      301 gcggggaaca ccgctgttgt tgcaactgat ttttattttt tatgggttgc cgacgattgg
      361 gatcgttttt gatcgtttcg aagcagcact cattgccttt atcttaaact atgcagctta
      421 ttttgcagag atctttcgtg gagggataca atcgattcct caaggtcaat atgaagcagc
      481 gcaagttttg caattaagtc cctttcaaac ggtgacgaaa atcgtcatcc cacaagtgac
      541 aaagattgtt ttaccttctg tagggaatga agttatcaac ttggtcaaag attcttcctt
      601 gatctatata ttaggtttag gtgacgtaat gcgtgctggg aaaatcgcga tggaacgcga
      661 cgcgacttta ctgcctttgc taggcgtggc aatcatctat cttacattga ctggtattct
      721 aacaatcgta atgaaacaag ttgaaggaaa attaaattat taccgctaac tgataggagg
      781 aagaaatatg attgaattga agaaagtgaa caaagcattt ggtgaaaaaa aaataatcaa
      841 agatttgaat ctaatcattc cagatgggaa aacattagct atcgtaggtc cttccggtgg
      901 cggtaaaacc acgcttttac gtatcttggc tggcttagaa agttctgaca gcggagaatt
      961 ttatttagac ggtgtaccgt tcaacccatt cgagcttaaa atgaaagaac aagttgtagg
     1021 agtcgtattc caagacttcc agctatttcc acatctgaat atttttgaaa acattacctt
     1081 agcaccaaaa atggtattga aacagacaaa agaagaatac accaaaaaag cagaagaatt
     1141 agcggcttca ttagggatta gtgatttatt gaatatctat ccttatcagc tttctggcgg
     1201 acaaaaacag cgggtagcga ttgccagagc attggctatg aatccacggg tattggctta
     1261 tgatgaacca acaagtgctt tagatcctga attacgccag caagtcgagc gtttgatcct
     1321 atcattgaaa gaagatgggg taacccaaat tattgtcacc catgatttag tatttgcaga
     1381 aaatgtcggt gatcaattac taaaagtttc cccaattcat taagaaagga gaagatagag
     1441 atgaaaaaaa ccagttttct attcgctttg atcgcaggtc ttcttctttt tgcaggctgt
     1501 tcgaacaaaa aaacttcagc agataattgg gcgactatca acgaagagaa aaaaatcgtt
     1561 ataggtttag acgatacatt tgttcctatg ggatttagag ataaagacgg gaagctcaca
     1621 ggatttgata ttgatttagc caaagcagtc tttgaacaat atgggattac ggtagacttt
     1681 cagcccattg actggtcaat gaaggaattt gaactgaaca atggaacgat cgatttgata
     1741 tggaacggct attccaaaac gccggcaaga gaaaagaaag tgcaatttac aaaaccttat
     1801 atggaaaacg atcaagtgct gatcacacct aaagaatcag gaatcacaaa ctttggacaa
     1861 atgaataata agagattagg tgcgcaaaat gggtcatctg gttatgatgt atttacgaaa
     1921 caaccagaag tattaaaaga gatagtcaaa aaccaagatg ctgttttgta tgatagtttt
     1981 aatgaagcat tgatcgatct gaaaagcaga cgggtcgatg gtctgctgat ggataaagta
     2041 tacgcagact attatttgaa acaaagaaac gaactagaag acttcaacat aacaaaaggt
     2101 tcttatgaga gtgaggattt tgcagttggt gcacgcaagt cagatagtac attagtgaaa
     2161 aaaatcaatg aagccctaga tcaactagag aaaacaggtg aattccaaaa aatatccgat
     2221 aaatggtttg gcgaagatgt tacgccgaga aattaacaaa taggggactg tgacaaaaga
     2281 cgtgtcacag tccctttttc cgaataaaca gtgttctcct gccaactcct tgtgactcgg
     2341 agctgaatgg caggctcaca acctcttggt aaacggtgtt caaaagccag tttttcggta
     2401 ttaagccaaa tttatgcaaa aatgtagaaa gccattttca caaaattttt cttactactc
     2461 gaaactaagc gactttttca caacctcctt tacataattt tattttgttg tggaaggggt
     2521 ttcgtgttat tctaaaagag gaacgattga aggttatagg aaaggaagag atgaatggaa
     2581 cacaaagaac ttacctcatt tccaaaagat tttctgtggg gctctgcttc tgcagcgtat
     2641 caagtagaag gagcttggca agaagatggg aaaggagaat cagtctggga tcgatttgta
     2701 cggatacctg gaaagacatt taaaggaacg aacggtgatt tggcagtaga ccactatcat
     2761 cgttataaag aagatattgc tttaatgaaa gaacaaggtc tgaaagctta ccgcttctct
     2821 gtagcttgga cacggatttt tcctaatgga cgaggagaag tcaatcaagc tgggctcgct
     2881 ttttatgaga gattgatcga cgaattgatt gaaaacgata ttgaacctat gttgacttta
     2941 tatcattggg atcttccaca agcattgcaa gatgaatata atggttggga atcacgtcag
     3001 atcattgaag atttcactca ttatgcagaa acattatttg aggcattccg cgggaaagtc
     3061 cattactgga ttagtttgaa tgaacaaaat atcttcactt cattaggtta tttgttagca
     3121 gcacatccgc caggtgtgac agacccgaaa cgaatgtatg aagttaacca tattgctaat
     3181 ttagcaaatg catctgtcat caataaattt cacgagttag aaatgcctgg aaaaatcgga
     3241 ccaagctttg cgtatacgcc aaattatcca attgacagta atcctgaaaa tgttctggct
     3301 gctgaaaatg cagaagacct gatggccaat tattggatgg atgtctatat gtggggaaaa
     3361 tatccgattg ctgccatgag gttcttagaa gaaaaaggat gggcaccaac gattgaagct
     3421 ggcgatgcag aattgctaga atctgctaaa ccagattttc ttgggatcaa ttactatcaa
     3481 acggcgacga atgcattcaa tccattaaac ggagttggtg ctggaaaaat gaatacgaca
     3541 ggaaaaaaag gttcatcaga agaaactgga gttcctggaa tgtataaaaa agttgagaat
     3601 ccatttgtcg aacgaacaaa ttgggactgg gagattgacc cagaaggatt aaggatcgga
     3661 ctgcgtcgta tcacaagccg ttaccgcatg ccggtactga ttacggaaaa tggcttagga
     3721 gagtatgaca agttgacaga agataaacaa atccatgacg actatcgaat caattactta
     3781 caaagccacg tcaaagccat caaagaagca atttcggatg gagcagaagt cctaggctat
     3841 tgcacctggt cttatacaga tttgcttagc tggctgaacg gttatcaaaa gcgatatgga
     3901 tttgtatatg ttgatcaaga cgaaacacaa gaaggatctt tggaacgata taagaaagac
     3961 agttattact ggtaccaaaa actgattgaa gaaaatggag agaaccttta gttcacatac
     4021 ttaaaacaag aaggtacggc tggatatggc cgtgcctttt cttgataaaa tcatttagaa
     4081 attaagaaaa actgtaaaat aagctgaaaa atgaaagaaa gcgtcagttc tttcaaacaa
     4141 aactttagtt cccttacttt tttttgtata atgaaacttg atgaaatgag ggataataaa
     4201 tggcacaaaa gaaacggcct actaaaaaaa ggaaaaagac gaaaaaaacg aaaaagcaaa
     4261 aacagcagca ggaacaaatg ctgacgattg gtgttgggtt tgccttgatt ttatttgctg
     4321 tcttcggctt tttaaaatta ggttttttag gaatattgat tgcaaacggc tttcggatca
     4381 ttgcaggaaa tacttaccaa atcctctgtc ttttattagc cgtattagga ttttggattg
     4441 tcattaagaa tacagagttt tcaattggta aaaaccgacg ctggtttggc ggcatactct
     4501 tttatttcgg tatcttatta ttgttacatg cccatttatt tggcaaactc catactgggg
     4561 aaccaaatat catggggacg acatgggatt tgttagccag tgatataaaa caaagtcaag
     4621 tagacaataa cgttggtggt gggatgattg gagcaatcct ttatcatttt acttacttct
     4681 tgattgcaca gcctggaagt tatttagcag cagtgctatt actggcagga ggagcattcc
     4741 tgttcagtaa tctggaaggc tatcagctgt taaatggtat ccaatcaatt ggagaacgag
     4801 tacaggaatt attggaaggt gatcctgcca agcaagctcg aaagcaagcg gcaaaggaag
     4861 agagaatgaa acagcgcgca gaagcgaaag aagcaaggcg cttagctgca aaagaagctg
     4921 cagaaaaaga agctgcagaa tatgagaaga aaaaagcggt gagccagcaa agggaaaata
     4981 ctgctgatga atggcaggaa ccagaaaata cagagccgga gcagctaagt tttgttccaa
     5041 tcgacagttt tcaagaaaat atccatcctg cgaatctaga gaaaccagta ccagatacac
     5101 caaaacagac caatacagca gaaggttttt cagatgagtt gccagaggat gacggtacct
     5161 cattagaatt tgagattgaa gcagaacagg aaaatcaaga ctatgaatta ccgacagttg
     5221 atttgcttga ttctatacca actgtggatc aaagtgatga gtataaaaaa attgaaaaaa
     5281 atatcggcgt attagaacaa actttccaaa gtttcggtgt cgatgccaag gtcgtcaaag
     5341 ccagcttagg accatccgtc acaaaattcg aagtccagcc ggctgtaggg gtaaaagtaa
     5401 gtaaaattgt gaacttaaca gatgatatcg cgcttgcttt agcggcgaaa gatgtccgga
     5461 tggaagcacc gattccaggt aaatcactga ttggtattga agtaccaaat ggaaagatca
     5521 gtatggtttc ctttagagaa atcatcgaag cacaaccaaa ccacccagat aaattactag
     5581 aagtaccttt aggacgtgat gtttctggac gggtacaaac ggctgatctt tcgaagatgc
     5641 ctcacttact cgtggctggt tcgactggta gtgggaagtc agtagcaatt aatgggatta
     5701 tcacaagtat attaatgcgt gctaagcccc atgaagtaaa actgatgatg atcgatccga
     5761 aaatggttga attgaatatg tacaacggca tacctcatct gttgacgccg gtcgtgacga
     5821 accctagaaa agcagcgcaa gccttacaaa aagtagtaca agaaatggaa gaacgatatg
     5881 aaaaattcgc ggcaaccgga gtaagaaata tttctggtta caatgaattt gttcaacaga
     5941 aaaacttgga aaacggaacg aaacatccaa ccttaccatt catcgtagtg atcgtagatg
     6001 aattagctga tttgatgatg gtagccagca atgaagttga agatgcgatt attcgtttag
     6061 cgcaaatggc tcgggcagcg gggattcata tgatcctagc tactcaacgt ccaagtgtgg
     6121 atgttatcac aggaatcatc aaagcaaatg taccttccag aatggcattt gcggtatcaa
     6181 gcggtacaga ttctcggacg atcattgatt ctaatggggc agaaaagctc ttagggcgag
     6241 gagatatgct attcttgcca atgggtgaga ataaaccgat ccgtgtgcaa ggagcattca
     6301 tttctgacca cgaagtagaa cgggtcgttc aatttgttac agatcagcaa gaagctcatt
     6361 atgaagagaa aatgatgccg acagatgaag ttgaaacgac aggtgctcca gaacagccac
     6421 aagatgagct gtttgaagaa gcaaaagcac ttgtcgttga aatgcaaacg gcaagtattt
     6481 cccttctcca aagaagattt cggatcggtt acaaccgagc agcacgttta gtagatgaac
     6541 tggaagctca tggagttgtt ggcccgtcag aaggaagcaa gcctcggaaa gtattcattg
     6601 agcaggaaga aacatcagaa acgttgccgg acgataatga catgtaaaac ttgtgtgatg
     6661 aagggttgaa aaacgaataa ccaataaaaa gacaaggcat gatgatacca aaagaaaaaa
     6721 tggttttttt ccatcttttc taatacggta tgatgtcttg tctttttagt ttttgtgaga
     6781 ttaaagttct attcgattta tttgtgaagt attgcattaa ggaaatgaat catgtatagt
     6841 atgtagcgaa actttgagaa aaagagggaa aatactttgg aaaaacagtc catttatggc
     6901 ttgacgaatg aagaattaat caattggttt atagaaaacg gcgagaaaaa attccgagct
     6961 gcccaagttt gggaatggtt gtatcaaaaa cgtgtaagta atttcacaga aatgacgaat
     7021 ctatcgaaac aattgatcga aaaattatcg gagcatttta tcatcaatcc tctaaaacag
     7081 atggtcgtcc aagaagcttc ggatggtaca gtaaaatatt tgtttgaact ccctgataaa
     7141 aacatgattg agactgtact gatgagacaa gaatatggct tgtcagtttg tgtgacgaca
     7201 caagtaggat gtaatatcgg ctgtacgttt tgtgcaagcg ggctgctcaa aaagaaccgt
     7261 gatctgactg ctggagaaat tgttgcacag atcatgatgg tccaacatta ttttgatgag
     7321 cgcaatcttg gcgaacgcgt ttcacatgtc gttgtaatgg ggatcggtga gccatttgat
     7381 aattacgaca atgtaatgga ctttttgcat atcatcaatg atgccaaagg attggcaatt
     7441 ggtgctcggc acattacagt ttccactagt ggattagcac acaaaatcaa ggaattcgct
     7501 aataacggct tgcaagtcaa tctggctatt tccttgcacg cgccgaataa tgaggtgcga
     7561 acatcgatca tgcggatcaa ccgaagtttc ccaattgaga aattgatgga agctgtggat
     7621 gagtatttag agaaaacaaa ccgtcgaatc acgtttgaat atatcatgtt gaatcaagta
     7681 aatgatagac cagagcatgc gcaacaatta gcagatctat taaaagataa gaaaaaatta
     7741 gcatatgtca acttgattcc atataatcca gtcagtgaac atgatcaata ttctcgcagt
     7801 ccaaaagctg atgtattgag attttatgat gtattgaaga aaaacggcgt aaactgtgtg
     7861 atacgtaaag aacatggtac agatattgat gcagcttgcg gacaattgcg aagcaagcaa
     7921 atgaaaaaaa cagttgccaa ataatcgtat cctactcgtt ttttcaatta ccataaaagg
     7981 agcagttttc ttaattaagg aactgttcaa cttaaataag agaaaagatt ctatagcgaa
     8041 agctataaag ctttttttga caagaaaaac cctcatcaag caaagaaatg tcctcaattt
     8101 gatgacagcc tgcttgatgg gggttttagc aattatttaa ctgattttct tatatccttg
     8161 ctggctttct tgtgtagcat gataagtttc tacgtcaaga atggcctgtt taaatttttc
     8221 tcgggtgatt tcataaggca catgtttaat atcatttgtt gccatggctt tatctaagat
     8281 tgcttctaaa tcggtcgtga cattgagatt catgtcggtt aacgatactg gaagttggtt
     8341 ctttttcata aacacataga ttttatcaaa caaatcgaac tgctgatcca tcatcaataa
     8401 ggtcagtaca ccataactga cagatgctcc gtgaaggtat ccctccattt tttctagaac
     8461 agtcgtaccg taatagaatg agtgtgccat agcagaatta tagttattgt taactaaaac
     8521 agaaaccaat ccggtagtaa caatgatatc cgaaacgact tgttcaattg catatgaggg
     8581 acgatcgtcg gcactatctt tcaatgcttg cgtaccataa gtcaagagac gatcaatgca
     8641 catttttccg atttggattc ctaatctatc cgtgtagcct agatcatcgc cacgagcaga
     8701 aaaagtagat tcgacttctt tggataaagc atcgccaata cctgcccata agtatttatc
     8761 aggtgcttcg gcaataattg ctgtatcaat gaaggtgtgt acaggtggtt ttgaaggaaa
     8821 gaagagtccg tccattacgc cttcttcgtt atagatgaca cataccgcag tgacgggcga
     8881 acagttcgaa ccaatagtgg gaaaggtgaa gactggttta gctagttttt caccaatgac
     8941 ttttacagta tcgcaagcac ggccaccacc gactgcaaac aggacgtctg ctttttggac
     9001 actttcatgc tggatcaact gttcaatatt tccataagtt gaattacccc cgtaccagag
     9061 actggcgaca acctctattt cctgtgtcaa agctactttt attttgtttt ctgcctttga
     9121 aagtgcagtc ttccctccaa tcagcactac ttttgtccca tattctttga cgattccatt
     9181 tgctttttca tacgcatctg ttccaatggt ataatttggt aagaaaacac tttgactcat
     9241 attcatttcc ttctttcttc gttgaaacgg gttaaaattt taaagagtga tcgatctgac
     9301 tgcggctgta gatggagtag aggtgaacct aagacaggat aagtgatgaa taaggtggca
     9361 tgaacacctt gaaatcatca ataagtatcc taaaaacgaa caagtacaaa aacattgaaa
     9421 acgacaataa tgaatttttg ttcctcttag tatttctacc gattcccttt gcttttttgt
     9481 aattatctaa aaattctaaa aattaagatt attatatgaa aacaggtttt atttgtcaat
     9541 tcataattgg ttttttttaa agcaaaagat aatctatatc atgatgaaca aacagagttt
     9601 tttcctccaa ttgatggctt tcctgatctt tcctattttg aataaagtgt ttctgtataa
     9661 ttttttattt tataagtaag ataaataatg aaagaataga gatactgatt ggtagctaaa
     9721 gatttttgag cgagaacatt tcgttttttc aaaaggactg ttagaataag caagaacaag
     9781 ggggaagacg tatgataatc agtgaatttg accgtaataa tccagtattg aaagatcagc
     9841 tttctgattt actgagactg acttggccgg aagaatatgg agacagctcg gcagaagaag
     9901 tagaagaaat gatgaatcca gaacgaatcg cggtagcagc ggtagaccaa gatgagttag
     9961 taggatttat tggtgcaatc cctcaatacg gtatcacagg ttgggaattg catccattag
    10021 ttgtagaaag ctcccgacga aagaaccaaa taggtactcg attagtcaat tacttagaaa
    10081 aagaagtagc ttccagagga ggaatcacga tttatttagg tacggatgat ttagaccatg
    10141 gaacaacgtt aagtcaaacg gacctgtatg agcatacatt tgataaagtg gcttccatcc
    10201 agaaccttcg tgaacatccg tatgaattct atgaaaaatt aggttataaa atcgtaggtg
    10261 tcttaccaaa tgcaaatggc tgggacaaac cggatatttg gatggcaaaa acgattattc
    10321 ctcgaccaaa ttctcaataa taaaaagagg ttgtgacaga agtaatcagc ttcaagaaat
    10381 aagaaggaat ttacgaaaat tacttcttga atttttgtga aattccaact tatttccgaa
    10441 gaagctactt ttggaacacc gtgtaccaga ggttgtgaaa aagtcgctta gtttcgagta
    10501 gtaagaaaaa ttttgtgaaa atggctttct acatttttgc ataaatttgg cttaataccg
    10561 agaaactggc ttttgaacac cgtttattca gataagggac tgtgacaaga cttttgtcac
    10621 agtttctttt tgtttattct tttttatctt tgtatggcaa taatagacaa tataacgaaa
    10681 attatttaat ggcttttgga agaccatgga aaaccttgta caaagctatt ttttctgaaa
    10741 aattccttga aacctcacga aaaaatcatt attttatgaa aaagacaaaa aaaagtgttg
    10801 attttttaat aattattcat taaactctta aacaacttca gaaaatatta attattctga
    10861 aaattccaat aaaggggtac gtaaaatgaa aaagaaattt acatttggtt tggttgcggt
    10921 atgcggcctt gtacttgctg gatgttatgg cggcagttca gccacaagca gtagttcagc
    10981 aaaaagcggt tcagcagatg gaggaggcgt atttaactta gtcgtgcctc aagaaatgcc
    11041 tacagctgac ttatcagttg caacagatac aatcagtttt acagcattga ataacgttta
    11101 tgaaggaatt taccgtcttg atgaagacag caaaccacag ccggcaggag ctagcgagtt
    11161 ggcagaagtc agtgaagacg gattaactta caaaatcaaa ttacgagaag acgcaaaatg
    11221 gtcaaatggt gatcctgtta cagcagcgga ttacgtttat ggctggcaac gaacagtaga
    11281 cccagctaca gcttctgaat atgcttacct gtatgcgcca gttgaaaatg cagaagacat
    11341 tacagctgga aagaaagata aatcagaact agggatcaaa gcagttggtg actatgaatt
    11401 agaaatcaaa ttgacgaaac aaacaccata tttccaatat ctgcttgctt tcccatcatt
    11461 tttcccacaa aaacaatccg tagtggaaga aaatggggat gcctatgcat ctgcaagtga
    11521 taaagctgtt tataatggac cattcacatt agaagatttt gatggaccag gaacagatac
    11581 agaatggact tataagaaaa atgatcatta ctgggacaaa gatacagtaa aactttctga
    11641 aatcaaagtc agtgtagtaa aagaatcttc tactgcattg aacttattca aagatggcca
    11701 agcagatgac gtgatcttgt ctggtgagtt agcacagcaa aacgcaaacg atccagctta
    11761 tacttctgtt aaagaagcgc ggacaagcta tatcgaattc aatcaacgtg aaaagaattc
    11821 accattcaac aatgtgaacc taagaaaagc tatttcttat tctatcgatc gtgaagcttt
    11881 agtaaaacaa gtactaggtg acggatcagt tgtctctaca ggattgatcc catcagatat
    11941 ggtaaaaagt ccaacaacga acgaagactt tgcaaaagaa gctggaaaat tagtttctta
    12001 tgacaaagat aaagcaaaag aatattggga aaaagcgaaa aaagaattgg gcgttgattc
    12061 tttagaattt gatttgatgg cttctgatga tgattcatcg aaaaaagtaa tcgaatatgt
    12121 tcaaaactca atccaagaaa acttggatgg cgtaacagtc aaaccaacac ctgttccatt
    12181 ctctgtacgt cttgaccgct caacttcggg tgattttgac gcagtactag gcggatgggc
    12241 tgctgactat gcagacccaa gcagctttac tgatttgttt gtcacaggta attcatacaa
    12301 ccgtggtcgc tggagcaatg cagaatatga cgaagcagtt aaagcagctt catcaacaga
    12361 cgctggcgat gaacaagccc gttgggatga tttccaaaaa gcaatcaaga tcatctctga
    12421 tgatatgggt gtcgttccgg tgtaccaaaa agcagaaggt cacctagtga atgaaaaaat
    12481 caaaggtatc gttcaccatg cggcaggcgc ttcatgggat tacaaatgga catacgttga
    12541 agaataatcg ttaataccgt gagcatgaga aaaaacgagg ctgcggcaaa tgtcgcaacc
    12601 tcgttctcat attcacttat cctaacaaag aaaaaagcat gaaaatagca gaaagagcaa
    12661 ttagtattcc ggcaatgatc agccaaaagc tgtacatacc gtagctggca gacgagagcg
    12721 tggaaaattc tggttttttc tttcggttcc ttgttcgtgc aagatggacc gatcgctgaa
    12781 aatgatcgaa gaaacccgaa gaaaagaccc ataaaaaacc gccgataatc agaaacggca
    12841 atgaccataa gaatagatca ttagataatt gaatgagtgt aaaggaatgg ttgatgagat
    12901 tttttattaa aataaccaga atcagtagaa aagctactgc gtaggggata gatttttttt
    12961 tcatttgatt gctcctttat ttttggttca ttatctaata atgtagcgaa acatctgtca
    13021 gaagtcaaaa gctaggggga aacattagtg aatagttata tcaaatatgt attaaaacgt
    13081 gtctttttca tgatcatcac gctttggtta attgcaacaa tcaccttttt cttgatgcaa
    13141 ttgctgccgg gcacgccata tacgaatcag gaacgtttga gtcctgaaac aatcgagatg
    13201 ctaaataaac aagtcggttt ggataaacca gttatcgtac aatatgggat ttatctttct
    13261 aatttgcttc aaggagattt tggaatttcc ttccaattta aaaaccagcc agtcgcacat
    13321 ttgttagctg gaagaatcgg accatccttg cagttagggt tacaggcaat tatctttgga
    13381 acagtcctag ggacgatttt aggaacgatc tctgccatga agcaaaatac atgggcagat
    13441 acatcttcta cactcgtagc gatattaggt cgttccattc caaactttgt atttgctgtt
    13501 ttattacaat atatctttgc aatcaaatta caagttttgc caatcgcaaa atgggatggc
    13561 tttgtgtaca caatcttacc aacaattgcg ttggccatgt cgccgcttgc tgactctgct
    13621 cggtttatcc gtacggaaat ggtggaagta ctgcatagtg attatgtgga attagcaaaa
    13681 gcaaaaggat tgagccgttg ggaaatcgcc tttaaacatg gtcttcgaaa tagtttgatt
    13741 ccattgatga ctttattagg accgttagct gtagcattga tgaccggatc actggtggta
    13801 gaaaatatct ttgctattcc tggtatcggg gaacaattcg ttaagtcaat cacaacaaat
    13861 gattatccta cgatcatggc tgtaacgatc ctttactcat ttatgctgat ttttgttatt
    13921 ttgatcgtgg atctattgta cggtctagtt gatccaagaa ttcgtgtttc agaagggagc
    13981 cgaggataaa tggaaatgat accaaagcgt tatgaaacag ttgcagatat ccctgcggat
    14041 gaatttcttc cattacaaaa aaataccgaa gaagaacgtg aacagattac tgcaccttct
    14101 ttgaatttta tccaagattc atggcgccgt ttaaagaaaa acaaagctgc cgttatttca
    14161 atggttttac tattggtcat cattttgatc tctgtgatca caatctttgt ttctcctcat
    14221 gatccaactg cccaaaacgt ggcttatatc aatttgcctc ctcgtattcc gggaatcaat
    14281 atcgatggat tgaatggaaa agcaatggtt ggtggtgaac ttgttgataa atatgctcaa
    14341 gcaaacgtcc cttcaaacgt aaatttcttt ttaggaacag acggtttggg acgtgatgta
    14401 ttaagccgct tatttatggg aatgagaatc tcgttgctga tcgcatttat tgctgcatta
    14461 ctagatgtaa cgattggtgt agcttacggg ttggtttctg gtttgttagg cggacgtgtc
    14521 gataacgtga tgcaacgttt tttggaaatc ttatcaggaa ttccaaacct cgttgtcatg
    14581 attttgatgt tggtcgtttt tgaaccagga attttttcaa tcgtggctgc tatggccatc
    14641 acaaactgga taccaatggc acgtatcgtt cgtgcacaaa caatgaaatt aaaagatcaa
    14701 gaatatgttt tagctggatt gacattaggt gaatcaagaa tgaaaattgc attcaaacat
    14761 attttgccga atatctctag tgtcattatt attcaaatga tgtttagtat tccatctgct
    14821 attttcttcg aagccttttt aagctttatc ggtttaggtc ttacgcctcc gtcagcttca
    14881 ttaggaacga tgttgagcga agggtacaag acattcctgt atctgcctta tctattatgg
    14941 attccggcag taactttatc ggttatcatg attggcttta acttacttgc tgatggattg
    15001 cgtgatgcct ttgatcctaa aatgaaagag tgaagacgat gacgaaaatt ttagaagtga
    15061 aagacttaga aatctctttt gatacgtatg ctggaaaggt acgagcgatt cgcggtgtca
    15121 attttcattt gaataaagga gaaacattgg cgatcgttgg ggaatctgga agtggaaaat
    15181 cagtgacgac cagaagcatc atgcgcttgc tgtcaagcaa cgccaatata gatgctggtc
    15241 aaatcctctt taaaggtaac gatatcgttg gaaaatcaga aagagagatg caaaaaatcc
    15301 gtggtaaaga aatagcgatg attttccaag atccaatgac ctctttagat ccgacgatgc
    15361 ccattgggaa gcaagtcgct gagtccctta gaaagcataa taaagtttca aaaaaagagg
    15421 gacaaaaagc tgcattagaa ttgcttaaat tagttggaat acccgaagct gagaaacgta
    15481 tcaacagtta tccgcatcag ttctcaggag gtcagcgtca acggatcgtg atcgcgattg
    15541 cactggtatg ttatccggaa atcctgattg ctgatgaacc tacaacagcg cttgatgtga
    15601 ctattcaagc acagattttg gagctgctga aagaaattca gacaaaaatc gatacatcaa
    15661 ttatctttat cactcatgac cttggtgtag tagcgaatgt cgctgatcgt gtcgctgtca
    15721 tgtatggagg aagaatcgtt gaagttggaa catcggaaga aattttctac aacccgcaac
    15781 atccctatac ttggggactg cttggttcaa tgccgacatt agatagtgcg aacgatcgat
    15841 tgtatgctat tcctggttct ccaccggatt tattgaaccc gccaaaagga gacgcattct
    15901 atccaagaaa tgaattcgcg atgaaaatcg atgcagaaca agaaccacca ttttttgaac
    15961 tatcaaaaac acacaaggca gcaacttggc tacttgctcc gcaggcaccc aaagtgacac
    16021 cgccagaaga aatccaacgt cgctgggcta tctttaaaga gaaacaaaaa catacttacg
    16081 gtcaaggagg aattgctgat gccaaataaa ctacttgaag ttaaaggatt gaaacagtat
    16141 ttcaatgtag gaaaaaagaa tgaagtacat gctgtaaatg acatcagctt tcacatttat
    16201 gaaggagaaa cattcggttt agttggagaa tctggaagcg gaaaatccac tactggccgt
    16261 acgatcattc gcttgaatga acctactgat ggtgagatat tattcgacgg tcaagatata
    16321 acgaagatca aagataaaaa aggtttgacg aaattccggc atgatgttca gatgatcttt
    16381 caagatccat acgcttcgtt gaatcctcgt atgaaagtca gagatatcat tgccgaagga
    16441 attgatgtta atggactagc taaatcatct gaagagcgtg caaaaaaagt cgatgatcta
    16501 ttgagaactg ttggattgaa tccaagccac ggtactcgtt atcctcatga attttcaggt
    16561 gggcaacgcc agcgtattgg tattgcacga gcattggcag taaaaccgcg ttttatcatt
    16621 tgtgatgaac caatttctgc actagatgtg tcgatccaag cccaagtggt caatttgttg
    16681 caagatctcc aaaaagaaca tcaattgacc tatctattta ttgcacatga tttgtcgatg
    16741 gttaaacata ttagtgaccg aatcggtgta atgcataacg gcttgttatt agagatggga
    16801 acaagtgatg aaatctataa tcacggtgtt catccttata cagaaagttt gttatctgct
    16861 attcctctac cagatccaga ccatgagaga aaacgcagaa gaatcaaata tcaacctgaa
    16921 ccagatgacg gacaagtacg tcaacttcgt gaaatcgcac cagaacattt tgtctatgca
    16981 actgagcagg aagtcccata ttacgcaaaa aaactaaaac gacaaaagga atctcttctg
    17041 gttgctaact aggagggaca tagatgctaa aagcttttaa attccgtatg tatccgacag
    17101 aagaacaaaa acagcaattg attcgtactt ttggatgtgc tcgatttacc tataaccatt
    17161 tgctgaaaaa gcggcagaaa agttggcaac aaacaggagt agccaatttt tcgctcacac
    17221 ccgctacatt aaaaaaagaa tacccattct taaaagaagt agacagtctt gctttagcaa
    17281 atgcacagct taatttggat cgggcttttc gcaattattt caagggacgt gccagcttcc
    17341 caaagcttaa aacgaaaaaa agtatgtggc aatcttatac gaccaacaac caaacccgta
    17401 cgatctatct ggaaaatggc tacttaaagt taccaaaaca aaaagaacta atcaagataa
    17461 atcagcatcg gccagttgaa ggatcgattc gctccgctac gatttctgct cgatataatg
    17521 aagaatttta tgtcgcacta ctttgtgatg tttcgccagt aaaaaaagaa tctttagcta
    17581 aatggatcgg gatcgcctat catccgaaga cattgatcca aacatctcga cctctagaag
    17641 taactttacc aaaatttcac cagacagaag aaaagctgca acatgcacag cggaaattga
    17701 atgtgaaagt ccgctccgct caccatagaa agatcaggtt agatcaggca agcaattatc
    17761 agaaacaaaa gagaaaagta atggatcttt atctgaaaca aaagaaccag cgagaagatt
    17821 atcttgaaca attatctggg aaattggtca aacaatatga ctacttattt gtagaatctt
    17881 ttccaaaaga agaggcacat gctgattttt ctattcacga ctggcataaa ttaataacaa
    17941 aattgcgtta taagtcccaa tggtataata aaaaatttct tttgatcaat accgacggag
    18001 cagaagaaag caattccgta agaaagagcc aagtagtaga aaaaatgggc agacattcgg
    18061 ttatcaaggg ataaaaaatg aatgaaactg ataggagcgt tagggttagc cttgttaata
    18121 aaaagtctta atgacttttg tttctaggaa tttttctttt gaagaaaagc tcactaatta
    18181 tgacaaacca ataaaacaat agcagaaaaa gttcgtacga gctttttctg ctattgttaa
    18241 ttttttattc agaaagttta cgaatacatc aaaattctga aacaaaaaac gtaactcaca
    18301 aagagttgtt tttgcgtttt ttcttgaatg attaggtctg aatcttttgc tcacaacctt
    18361 attcatggtg ccccggcttg agctgataga tttttgaagg acggccgatt cctacaggac
    18421 gttcaccgat ctcatcgaaa tattggagca tagctttctt aaaattggaa tgatcgatcg
    18481 ttttataatc gatccctaag aatttagcaa atacttttcg agcttccgta atcgtgaaat
    18541 ctttacctaa aacttgtaga acttgcggct cgtgttccat tttattgact acacggttga
    18601 atgctttcaa gatgatttga ctatggtcaa aagccaaagt atctttgcca gaagactctc
    18661 cagtgactaa atcaagcgag atagccactt ctccgctaga taaatggatc ttgttactat
    18721 gacgttctag tgtgaaccag cgtacttcct tggcatcatc tccggcgatt agcggttctt
    18781 ctccaataaa ggctaagtag ctgactgtga cgacccagcc tcgcggatct cgattaggcg
    18841 tactgaatgt atgcagttgc tcaatatttt cttttgaaat aaccacacca gtttcttcct
    18901 ttgtttctct taagacgctt tctccagttg actcatcctt ttggacaaag ccaccaggca
    18961 atgcccatga atttcgataa ggatgccctt ttctttggat caacaaaact ttcagctgat
    19021 cttcttcttt gttatagcac atcagtacga tatcgacagt caaagagggc ttgtcatatt
    19081 ctggacgttc ctgtttttga taccagttaa gaaattcttc ttcacttgct ttatgttcat
    19141 aatataattt ttcttcttct ttagaagcaa aacggttcat ctgaccacct ccattgacag
    19201 taaaagtact ttttacctta ttgtagcaga ctctgaaaaa aaaccaagga tttacttgaa
    19261 aaatctaggt tatcatttaa atatgaaaaa taaatggaag tatgagattg aataaaaaga
    19321 aaagcagata aaacggcaat actttatacc gctcttcacg aatggcaaag aagccacaaa
    19381 taacgatata tacgtcaatg ataaaacgca aaatccaagc tgctgtcata aaactgttca
    19441 aatgcccatg gaggttaaaa taaccataca tacgaatata aaaatagctg aatattaaat
    19501 gtgctaatga aagaaaagca atactaagtg taaaaaaaag atgtttcttc tgcatgattg
    19561 ttccagtccc ttactaagat agatagtctt tattatacca cgtgtgaggg gagaaataaa
    19621 aagccgtttt ttagtagata tgaaacaaaa caaaaacccg catttattca acctattcat
    19681 ccttttaaag gatagattga acgtagatag aagtcgttta tccagtcttt ttcattttga
    19741 aaaaaagcta acagcatgct ttttttatgg tatactagca aggaaacgaa ttcgcatcat
    19801 gcgataaagg aggaagagcc ccgtggcaga aaaggaaact ttttatatca ctacgccaat
    19861 ctattatcca agcggcaaac ttcatatcgg caactcgtat actacgattg catgtgacgc
    19921 aattgctcgt tataaacggt tgatgggctt tgatgtgttt tatctcactg gagtggatga
    19981 acatggtcaa aaaatcgaaa caaaagcaga agaactaggt gtaaaaccgc aagaatatgt
    20041 agataaaatg gcggctgatg tcaagaaatt atggaaaacg cttgatatca gttatgataa
    20101 attcattcgc acgacagatg attaccataa agcagctgtt caaaaaatat ttgatcgttt
    20161 attagaacag ggagatattt acttaggtga atatgaaggc tggtactctg tttctgacga
    20221 agaattcttt acagaaacac aacttgcaga agtgtacaaa gatgacgaag gtaacgtgat
    20281 cggtggtaaa gcgccaagtg gacacgaagt agaattggta aaagaagaat catacttctt
    20341 ccgcatgagc aaatacgcag accgtctatt ggaatactat gaagaacatc ccgaattcat
    20401 ccagccagaa tctcgtaaaa acgaaatgat caacaacttt atcaaaccag gattagagga
    20461 tcttgcagtt tcacgaacaa cttttacttg gggagtacca gtcaagagtg atccgaaaca
    20521 tgtggtgtat gtatggatcg atgcattatc caattatatt actgcactag gatatggctc
    20581 cgaagatgaa agtctattcg aaaaatactg gcctgcagat gttcagatgg tcggtaaaga
    20641 aatcgttcgc tttcatacga tctattggcc aatcatgctg atggcccttg atttgcctct
    20701 acctaaaaaa gtatttgggc atggctggct attgatgaaa gacggaaaaa tgtctaaatc
    20761 aaaaggaaat gtcgtttatc ctgaaatgct tgtggaacgt tatggtttag atgcactccg
    20821 ttattatttg cttcgtgctg ttccgtttgg gtcagatggt gtctttacgc cagaagattt
    20881 tgtttcccgt gtcaattatg atctggcaaa tgatctaggg aacttattga atcgaacgat
    20941 tgctatgatc aacaaatatt gtgatggact cgttcctgac tatgcctcac ttgtcactcc
    21001 atttgatagt gaactgtcta cgacggctgc taacgttgtc ggacgttacc atgatgcaat
    21061 ggaaaaaatg gaattcaata cagcattggc tgaaatctgg gtgctgattt ctcgtgcaaa
    21121 caaatacatt gatgaaacag aaccatgggt attagcaaaa gacgaagaaa agaaagctga
    21181 attgaatagt gtcatgatcc atttagctga atctttgcgt atcgcagcga tattacttca
    21241 gccaatcatg acagaaacgc cagagaagat cttcaatcaa ctaggattgg actctgaaac
    21301 aatgaatctt gaaggattac actttggcga atttccttca ggaacaaaag tagttgcaaa
    21361 aggtacacca atcttcccac gtttagatat ggaagaagaa gttgctttta ttcaagaaaa
    21421 aatgtctgaa ggtactcaaa caaacgaaga tacagtcaaa tgggatccag aagaaacaga
    21481 acttgtttca acgaaagaaa aacaaatcaa atttgatgta tttgaaaaag tagaactaaa
    21541 agtagcagaa gtcatcaact gtcaaaaagt agaaggggca gataagttgc tgcaattccg
    21601 actagatgct ggagacagcc aagaccgtca aatcttgtca ggaatcgctg aattttatcc
    21661 tgatccaagc gaattgatcg ggaaaaaagt cgtcattgta gcaaatctga aaccacgaaa
    21721 gatgcgtgga caaatcagtc aaggaatgat cctttctgca gaagcaccag atggctcttt
    21781 acaagtaatc gaagcaccaa aatccatgcc aaatggctca gaaatcgcat agaaattcaa
    21841 agggggtatg acactagttg tgtcataccc cctttttccg aaatttgaga agcaattttc
    21901 gtaaattcct tcttattact tgaagccaat catataatac agaaacagag aactatccaa
    21961 aataaatcct agaaaaagaa gtacgagctt cgctgatttt tgttaattta gaataatact
    22021 aataggaatc gtaaaaacag aaaaaaagca taatgataaa gggtcgggca gattttaatt
    22081 gattcatctg gtactctttt ttattgtcct tacattcata aagtttgaat gcaatgactt
    22141 tattacatct atatttatat ctaacagtag cgttgatgtg ttaattataa gttctatcac
    22201 tttatgttca attagtttgt gctcttatat gtgtgattga aaatatagat aaaaaaacaa
    22261 tcatcggctt tgacttcgat gattgttttc tttattttgt aaaaatccta tcacttgatt
    22321 ttatggtaac cttttatttt tgtcttcaaa cggcttggta agagagcagt aagcagtgca
    22381 aatgggatcg aaaagacata ccagaaaatc gtacgtccga taccataatg ttgatagagc
    22441 tttgtcaaca tcacgtgtaa caagatcaac cctaaaagca aggagccagc tataaaccaa
    22501 tgattatccc aatgcatgac ttcactaagt gccatcactc caaaaggata gaaataaaaa
    22561 tagatcccga ctaaggtcat ccgccagttc tttgtaaatg ttccgatatt caataaaaag
    22621 aaaatcgctg aaagcaaaat accgataggc ggaaaaagcc caaccaaaaa ggaatacaac
    22681 atcccccaca agatcatcac aggacctttg atcaatgcaa cgattgcgat gaacaaagtc
    22741 agcaatatta gtttttgtga taacgttgca acagtcatta atccaaataa aattaatgtg
    22801 aaccaatgcc aatgggactg ctgttgttct ttacgggaaa aatcgacccg gttggataaa
    22861 taatctgcta atttcggata agaacgctta aaatccataa actgttcctc cttcgtggaa
    22921 aaggtaggtt tagtatacga aaaataaaaa agaaatacat ccgtcttaag agggagtttt
    22981 tcactgaaag tggagaaaaa agaatggtaa attaaaatat tctcagttat actgaaaatt
    23041 ataccaaatt tcaaagaaga aagaggatgg gaatgaaagg caaactaaaa cgagaaatca
    23101 atctgtttgg cgcattagct accgttatgg gaaccgtgat cggtgcaggc gtcttcttca
    23161 aaactgctgc tgttactgct agtactcagt ctacaagttt gacattgcta gcttggcttt
    23221 tgggtggttt cttaacgatc tgtgctggat tgacagtggc tgaattagct acagcaatcc
    23281 cggaaactgg tggagctgta aaatatattg aagctgcgta tggaaaattg cccagctttt
    23341 tattaggatg ggcgcaaagc ttgatttact ttcctgctaa tattgctgca ttatcgatta
    23401 tctttgcgac acaattgacg aacttattac aattatctac cgattatctt ttgttgattg
    23461 cagtgatcac cgctgtttct gtgacagggt tgaatttgtt agggacaaaa gtcggtgctt
    23521 ctgtacaatc agtgacgttg attgttaaat taataccaat tgctgtgatt gtcatatggg
    23581 gattattgac cccaggacaa ggaactgtcc agttatttcc aatcgaagct ggaaaagatg
    23641 ttacttttgt cgaaggattg agcagtgcgt tgttagcaac gttgtttgct tatgacggct
    23701 ggttaggtgt cggtgcaatg gcaggggaaa tgaaacggcc ggaaaaagat ttgcctaaag
    23761 caattattct tggtttgagt tttgtaacag tcgtttatct attgatcaat tttgtttttt
    23821 tgaaaacttt gccgattgat catcttgccg gtaatttgaa tgcagcttct gaagcatcag
    23881 acgtcatttt tggaggaatc ggtggaaagc tggtcactat tgggatcttg atctcggtat
    23941 acggtgcatt gaacggttat acactaactg ggatccgcgt gccttatgcg atggctttag
    24001 aagacgagct acctttcagt aaacagctga caaagctttc aaagaagttt acggttcctt
    24061 atgttcctgc ggttttccag ttagcagtag cttgtattat gatgagcctt ggttctttcg
    24121 actttttaac agacatgttg atttttgtga tgtggctatt cagtttactg atttttatcg
    24181 gtgtctttat tttaagaaaa aaagcgccgg aattgccacg tccatataaa gtaccacttt
    24241 atccaatcgt tccgattatt gcgattctcg gtgctatttt cattttaggt atgacgatga
    24301 tgacgcaaac gaaattagca ttgatcggta taggtgttac cttgataggt atcccagtct
    24361 attatcaaaa aaagaaaaaa cgctcagaag agtaaaatat ttcaacaaca gacagaaaaa
    24421 gtacgaacta ggtcctctag atcttcgtgc tttttctatt tcaataaaac aagttcttct
    24481 attttgattt ttgctacttc tgcaagtagt gcttatgtgc taaagtaaga atgaaaagga
    24541 gagataaaca tgatatttga ttctcatacc catttaaatg ctgaacagtt caatgaagat
    24601 attccagaaa cgattcagcg agcacaagaa atgggggtaa cgaaaatggc ggtcgtgggc
    24661 ttcgatacgc caacgattga aaagtctttg caattaagcc atgactatcc aaatatatac
    24721 agtattatcg gctggcatcc gacagaggct ggcagttata cgaaagaaat cgaaaataaa
    24781 ttacaagaac aattgacttt accaaaggtt gtagcattag gggaaattgg cttggattat
    24841 cattggatgg aagacccgaa agaagtccaa gataaagtat ttcgcagaca gattgctatc
    24901 gcaaaagaaa tgaacctacc aatcagtatt catactagag aagcacttga agacacgtat
    24961 caaatcctaa aagaagaaga tgttcgagat atcggtggaa tcatgcatag tttcagtggt
    25021 gattatgaat gggcaaaacg atttcttgac ttagggatgc atatttcatt tagcggtgtc
    25081 gtcactttca aaaaagcatt agacgtccaa gaggctgcag caaatgtacc aatcgaacga
    25141 ttacttgtgg aaacagatgc cccttatctg gcaccagttc cttttagagg aaagcgaaat
    25201 gaaccaggct atactcgtta tacagtagaa aagattgctg aacttcggaa tcttccgaca
    25261 gaagaagtgg ctgcccaaac atggacaaat gcgcaccgat tatttggtct aagcgaacat
    25321 ggataagatg aagatccaag agattatagt cgttgaagga aaagacgata caagaaggct
    25381 gcgggaagta gttgatgcag atacgataga aacaataggg tctgcaatca atgaagagat
    25441 cctgatgcaa attgaacatg cccaagagac tcgtggagtg atcgttttta ccgatcctga
    25501 tttttcagga gaaaaaataa gaaaaatcat tatggaagct gttcctcagg caaaacatgc
    25561 ttttttgccg cgcacacaag ctaaaccaaa gaaaaaggga agccttggtg tcgagcatgc
    25621 aagtgatgct gctattttag aagcattgaa aaaggtcgtg acgccagaca tttcccaaac
    25681 ggctgtttct gaaatcacta gacaagacct tttagactat ggtttaatag ctggggcaca
    25741 agcaaaagaa aaacgagaaa aactaggtga cgagttgcgc atcggttaca cgaacggcaa
    25801 acaattggaa aaacgtttga agatgtttcg tattacgccg aaagaactcg cccaagcaat
    25861 gaaaatagtg gaggaacaac atgagtgaat atcgtgaaat tgcgacaccc tctagaacaa
    25921 aagagatttt attgaaacat ggtttttcat ttaaaaaaag tttaggacaa aattttctga
    25981 ctgaaccaaa tattttaagg aaaatcgtag aaactgcgca aatagatgaa catacgaacg
    26041 tgatcgaagt tggaccagga atcggtgcat tgacggaaca attagccaag catgcaaaac
    26101 aagtcgtagc atttgagatc gatgatcgtt tgatccctgt attggctgat acgatgcaac
    26161 cctatgacaa tgtgactatt gtacatcaag atattttaaa gaccgatttg tcaacagctg
    26221 ttagagaaac atttcatgag gagcttccgt taaaagtcgt agcgaattta ccttactata
    26281 ttacgacacc gatcatgatg cattttcttg aatcagattt ggttgtggat gaactagtcg
    26341 tcatgatgca aaaagaagta gctgatcgta tctctgctga accaggaacg aaagcttatg
    26401 gttcattatc gattgctgtt caatattata tggaagccag tttagcattc atcgtaccaa
    26461 aaacagtatt tgtccctcag ccaaatgtag attcagcgat tttgaaactg acaagaagag
    26521 atataccggc agtcgaagtg acagacgaaa aagcattttt ccgattgaca aaagcggcat
    26581 ttcagcaaag aagaaaaacg ctttggaata acttgcagca ttcgtatggc aaagatgacc
    26641 agacaaaagc atggttagca aaaagcttgg aaacagctgg aatcgatcca aaacgtcgtg
    26701 gggagacttt gtcattacaa gaattcgccg cattaagcaa tgcgatgtca gaaaatatgc
    26761 agtaaaaaaa gaggttgtga cagaagttgt gaaaaagctg tcctgcatca agtaataaga
    26821 acagccaaac aaaaatagtt cctcatgttt ttcgtttgtt tgggcttatt accgcagatg
    26881 caagcttttg aacaccgttt aagaaagagg ttgtgggcct gccgtttaac tctaagtcac
    26941 aaggaacaat ttcaaaaaac agcttctcat gtttttgagt tagttggtct tattacttga
    27001 tgcaagcttt tgaccactat tatgccgaac aaggagatgt gacacaaatt ttgtcacatc
    27061 tcctattttt gtttcttgat caaaaaattc ttatacttga tactcacact cattttgtat
    27121 ggatttagaa aagaatatgt gtcttgacag ttattagtaa gtgagttata ctaagtcgac
    27181 atttatgtgt caagacatat taggagagag aaaaaatgag aaaaaattca gttcgaaaac
    27241 taacgatttc tgctttattg attgggatgg gggtcattat cccaatggtc atgcctaaaa
    27301 tcatgattcc accagcttcc tttactttgg cgtctcatgt gccattattt attgcgatgt
    27361 tttttacacc aggagttgca gtggctgttg cgctaggtac gacatttggt ttctttttaa
    27421 caacgccggt tatcatcgca ttgcgagcat tgtcacatct tgtgtttgcg ttgattgggg
    27481 cttggtactt gcaaaagcat ccgagtatcg ttttaaaaaa tggacagttt acttttgcta
    27541 attggcgttt ccaagggttc aattttgtga tcggtgtgat tcattcttta gcagaaatgc
    27601 tagtagtcag catcttttac tttattggta atatgcctga aacatattat tctcaaggat
    27661 atttttatac agtattcatc ttgatgggga ttggtgggct tatccacagt ttagttgatt
    27721 ataatattgc ttattttata gcaggaacac tcagcaaata ttttgatatc cccgtattta
    27781 cggcagcaaa aaaagaaaat cggaaagagt cgattcaagg gtacgcgaag aaaacgacat
    27841 attagacatg atctctcaaa aaaaaaactc tcatctagta atggataata aatcctctaa
    27901 gatgagagtt ttttgtccta aaaagagctg caccaacatc ttctggcaca gctctaacag
    27961 ggggcaattt atggaagttt gatgacttgt tctgtttctt tatcaaagaa gtggcctttg
    28021 ctgatgttga aggcaaggtc gactatttcg cctggtttat ggaaatctct tgcatctact
    28081 tttgagatga actcagtaga accagttttt gtgtaaagca tcgtttcagc tccaagtaat
    28141 tcggaaacga caacttctga tttcactacg gcttcaggtg aagcttcaag ggctacttgt
    28201 tcactgtgga tgtcttctgg acgaataccg aagataactt cttttccttc ataacctttt
    28261 tcaactaata ctttgttttt tccttcagga atacgaagct taagcccatg tccatctgtg
    28321 ataacaccat ttttcaatgt cacattaaag aagttcatgg caggagatcc aataaagccg
    28381 gcaacgaaca tattgacggg tgtatcataa acttctttcg gtgtaccgat ttgttggata
    28441 aatccgtctt tcatgataac gattcggtca gccatagtca ttgcttctgt ctgatcgtga
    28501 gtaacataga tggtcgttgt ttcaagacgc tggtgaagtt tggcaatctc agcacgcatg
    28561 gctacacgta atttagcatc taaatttgat aatggctcat ccattaagaa gacttttgca
    28621 tcccgaacga ttgcccgtcc caatgccaca cgttggcgtt gtccaccaga taaagcagct
    28681 ggttttcgtt tcaagtattc tgtcagacct aagatctctg ctgcattgtc cacacgtttt
    28741 ttgatgtctg ctttatcata tttacgtaat ttcaagccaa aagccatatt atcaaaaaca
    28801 gtcatatgag gatacaatgc gtagttttgg aaaaccatgg caatatcacg gtctttaggt
    28861 gccacgtcat tcatgacttt tccgccgata tttagttctc cttcagagat atcttccagt
    28921 cccgcgatca ttcgcaaagt agttgacttt ccacaaccgg aaggaccaac aaaaacgata
    28981 aattcacggt ctttgattga tagattaaaa tcagttacag aataattttc tgcattgtca
    29041 tattttttat atacgttttt cagagccatt tctaccataa tacgttccac actttctttt
    29101 ttagttttat taactattta aagtataaat gaaagcgtta actaacttca atgtcatgtt
    29161 gaacaagaat tttttctttt ttttgtcaat gtgctagttt taagctttaa taaatatcca
    29221 taagaaataa aaactgatac actggagtaa ataagtatgt taacaatatc aaaaggagtg
    29281 tctcttatga aaatcgcttt gatcgctcat gaccgaaaaa aacctatgat ggtgaaatta
    29341 gcaacagcgt ataaaacaat attggaaaaa catgaacttt ttgctaccgg gacgactggg
    29401 cagaggatca cggaagcaac cggcttgccg atccatcggt ttaaatccgg accgttaggc
    29461 ggggatcagc aaattggagc catgatttcg gaggatcagt tagatttggt gatttttctt
    29521 cgagacccgc tggctgcaca gccccatgaa ccagatgtaa cagcacttat ccgtttatct
    29581 gatgtctatg agattccgtt agctacgaat atcggaacag ctgaggtgct actaagagga
    29641 ctggaagccg gcttcctaga ttttcgaaga atcgtccatg aaatagacaa gcatccactt
    29701 tcattttgat ggataagcgt atggaaaaat aacgtttaat gttcgcctat atgtagctat
    29761 aaaagctaaa caaactgata atatgcgata taatacgaac gtattggata atataaacaa
    29821 taatattagt ttttcgtatt tgcagtaaat gtgaaaatat gctatagttt ctgtgggaaa
    29881 agatcccaaa aataatacag agtagaaaat aaagcgttaa gtgctaagag gatgggatgt
    29941 tgcctcttgg acgaaggacg taatgttcgc ggttttattt tcgcattcgc tgcatgatac
    30001 gatgtagcag ctcttaaagg agatgctaaa aatgaagaaa caccggttag acgcacgtat
    30061 gattgctatt atgggcttat tgattgcatt gatggtcact ttgtcccgac tggtagcaat
    30121 cgagacccca tttattaaaa tcagtgtcac atttattcca caagtgatca tgggcattct
    30181 ttttggtcct ttttggtcag ggataggcgc agttttagct gatttagtag gaatggccct
    30241 cttctcgaaa tctgcattct ttattggatt tacattgaat gcatttattg aaggagcaat
    30301 ctacggattc tttttctatc gaaaagagat cacttggaaa aatgccattc tggctacgct
    30361 tagtgtcacg ctgatcatca acttattttt gacaccatta tggcttgcgt tgatgtacca
    30421 tgtgccattg ttcagctggg tcgtttgggc gccccgcctg ttaaaaacag taatatggtt
    30481 accgattcaa tcaattgcca tttattacgt aggacgtagt attccttaca aaaaaatttt
    30541 aagaagttta gcgatccacg ctaaataaaa aacaagcagt cttcccatcc cagaagactg
    30601 cttgttttta ttgtgctgtg aattgtgctt gatagagccg tcggtaataa ccatcttttt
    30661 gaagcagctc atcatgggtg cccatttcga caatagctcc ctgatccatc actaatatct
    30721 ggtccgcatt tttgattgtg gacaggcgat gggcaatcac aaaactggtt tttccttcca
    30781 tcattgctaa gaaggcttgt tggatttttt tctctgtcaa tgtatcgact gagctggtag
    30841 cttcatctaa gatcaacata gggggattac tgatcatcgt tcgagcaatc gtcaacagtt
    30901 ggcgttgtcc atctgatatc tttaaccctt gaccgccaat cttagtatct aatttttccg
    30961 gcaaacgttc tacaaattca tacatataag aggcttttag ggcatcattg atttctgcgt
    31021 cacttgcttc cggattccca aaacgaagat tttctcgcaa tgtactgtca aatagccaag
    31081 tatcttgtaa caccattcca aaacttttac gtaatgtatc acgttggata gagcggatgt
    31141 catggtcatc gactgtaatt gttccttttg ttgtgtcata aaaacgcatc agcaaattaa
    31201 caagtgtgga ttttccggcc cctgtttttc ctactatagc aatggtttga cctggataag
    31261 cagtaaaatt gaaatcttcg atcaaacgct gcttggggtc ataagaaaaa gaaacatgat
    31321 caaaagagac ttttcctttg atatttttgg gttccaaggc ataggcatct ggcaaatcag
    31381 gcttttcttc tggctgatcg atcaaatcaa atgctcgttc tagaccagaa aaagcggttt
    31441 gcagttgtgt cgtgattcca gaaagttcga taaatggttt agaaaactga cttgagtaga
    31501 tcgtaaagct ggaaatcaca ccaacagtga ttgacgaacc actcttcaat gccaataggc
    31561 cgccaactaa accaatcgat aaataagcaa ggtgatctac aaaacgagaa gacgggtttg
    31621 tcaaggaaga agaaaattgt gcccgttgtc ctttttcata tagatcagca tttagcagtt
    31681 caaattgctg ttgactagct tcttcttgct gaaaagcttt cacgattttc tggttaccga
    31741 ttcgttcggt cacaaagccc gagatatccc caataatcct ttgctgtcta tcgaaatttg
    31801 tttgtgaagc acgagcaacg atccaactca caaggaaaat aattggtgta gaacaaagaa
    31861 cgaccaatgt cagaagtgga cttagacgca tcataaaaat aaacgaaaga atgatgattg
    31921 ccactccaga aaataattga ttgaaggccg cagaaattgc aatggaaata ttgtccatat
    31981 catttgtaaa tcgactgacg atatttccgt gggagttttg atcataataa cgaagtggca
    32041 atcgattcag atgagcaaat gcatcttttc ttaattttgc aacggataag taagctaacc
    32101 gattgcttaa cacttggatg agccattgac tgactacgtt gattaaaacg ataccaccga
    32161 atagaataag taaatggaac agtcgattga agcggacctg tccttctcca atcatttgat
    32221 cgatactttg accaatttgt aacgtcatca caactgttgc aatcccattg atgattccta
    32281 gtatcacagc tagccaaatg tcttttgcat aggcagtaag gtaaggaatg aatcggcgga
    32341 gcgtctgcaa ggataatttt tttactttca taactattct tcctcctgtg atgcgacgat
    32401 ttcctgatat tctgctgatt gagcaagtaa ttcttcatgg gtaccctgag cagcaatctt
    32461 accttgatcc atcactaaga tatgatgtgc ttcttgaata gagcggacac gttgggagat
    32521 aataatcact gtactgccaa gataagtctg tagcgcctta cgcaaatcca agtctgtttg
    32581 ataatccaac gcacttaaag agtcatctaa aatcagtaat gctggcttgg caatcaaagc
    32641 tcttgcaatc gtcagtcgct gtttttgtcc gccagagaaa tttttcccat tttccatgac
    32701 ttttgtatct aaaccatttg gaagctgacg gacaaattct tctgcctgag cgattttcag
    32761 agcttcccaa cattcttttt ctgtggcgtc tttcttaccc cattgaaggt tttcacgaat
    32821 agtcccggta aatagtacag aagtttgggg aacaagagca atttgctgac ggagatgatc
    32881 cagctgccaa gaacgaacat ccattccgtc cattataact gtaccggaac tgacatcata
    32941 gaaacgcgga atcaattgtg tcaaagtcgt tttcccgctt ccggttggac caatgattcc
    33001 aaggactgta tttcgcttca gctgaaatgt aatattttgg agagaaagac cagaatcagg
    33061 agtataacgg aagtcaacat ggtcaaaagc gataattgct tcagaagaaa aatcgggagt
    33121 agtactgacc tcagcttcaa gaatcgaatt ttctgtgtct agcacctctt tcacccgatt
    33181 tcctgaagct tcggcacgtg tgaagatcac gacgaggttt gaaacaacga tcagtgccaa
    33241 aagcatttga ttcatataat tgatcaaagc aagaacttgt ccttgttgca agctaccaat
    33301 atttactttg atcccgccaa ctgtcagcaa acagatgatc ccgacattca tgatcaaggt
    33361 tgtagcaggt gataataggg cagagatatt ggaaacacgt aaataattgt tcgctagatc
    33421 atttgtgctt ttatcgaact tctctgtttc tttttttgtc tgcgcaaatg cgcggatgac
    33481 acgaacaccg ctaagattct gactaacgtg ttcattgagc tgatctagtt tttcttgcac
    33541 tttttggtag agaggaacgg tttttttgat gataaaaaat aaaatgattg agaaaatagg
    33601 caataatgct aagaaaaaca gacctacttc ccagtcgatc acaaaagcca tgaccactga
    33661 cccgatactt aaaaacggtg ctctgatcaa taaacgaatg accattgcta aagctagctg
    33721 aagctgattg atgtcgtttg tcattcgggt gatcaaggta tctgttccaa aatgattcaa
    33781 ctcgttgtga gagaaagtat tgattttttt gattagctga ttacgtaact ctgtaccaaa
    33841 tccttgtgaa gctactgaag catagtattg gcaaatgata gcacaaatca gaccaatcac
    33901 agacatagcg accatccata agcccatttc aatgattttt cctcggtcat tcatttttag
    33961 tccattatcg atcaaggaag ccatcattaa aggcaggaca agttcgaaga cagcttcaag
    34021 aaatttgaag aacgggccca aaatgatttg cttacgatag tcttttgcat aacgtaataa
    34081 ctgaatcata tgattcctcc tattatttat ttgtccacaa ttgaaaaaac aagtactacc
    34141 acattgtagc ttaggaaatt tagaatgaaa agagaacaag ccttttcata aatgaaagtt
    34201 ttattatgaa gaagcttt
//
LOCUS       DAFLWQ010000028        34003 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.029, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000028 DAFLWQ010000000
VERSION     DAFLWQ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.029"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(27..1259)
                     /locus_tag="L1V16_001267"
     CDS             complement(27..1259)
                     /locus_tag="L1V16_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBN1275616.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1514..2083
                     /locus_tag="L1V16_001268"
     CDS             1514..2083
                     /locus_tag="L1V16_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1275617.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2261..2701)
                     /locus_tag="L1V16_001269"
     CDS             complement(2261..2701)
                     /locus_tag="L1V16_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBN1275618.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2859..3623
                     /gene="map"
                     /locus_tag="L1V16_001270"
     CDS             2859..3623
                     /gene="map"
                     /locus_tag="L1V16_001270"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBN1275619.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3655..4578
                     /locus_tag="L1V16_001271"
     CDS             3655..4578
                     /locus_tag="L1V16_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBN1275620.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4803..5042)
                     /locus_tag="L1V16_001272"
     CDS             complement(4803..5042)
                     /locus_tag="L1V16_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1275621.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5047..5466)
                     /locus_tag="L1V16_001273"
     CDS             complement(5047..5466)
                     /locus_tag="L1V16_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1275622.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(5693..6931)
                     /locus_tag="L1V16_001274"
     CDS             complement(5693..6931)
                     /locus_tag="L1V16_001274"
                     /inference="COORDINATES: protein motif:HMM:NF017760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1275623.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(7038..7673)
                     /locus_tag="L1V16_001275"
     CDS             complement(7038..7673)
                     /locus_tag="L1V16_001275"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1275624.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            complement(8015..8650)
                     /locus_tag="L1V16_001276"
     CDS             complement(8015..8650)
                     /locus_tag="L1V16_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1275625.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            9162..10304
                     /locus_tag="L1V16_001277"
     CDS             9162..10304
                     /locus_tag="L1V16_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBN1275626.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            10297..10503
                     /locus_tag="L1V16_001278"
     CDS             10297..10503
                     /locus_tag="L1V16_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBN1275627.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            10582..11775
                     /locus_tag="L1V16_001279"
     CDS             10582..11775
                     /locus_tag="L1V16_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1275628.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            11980..13119
                     /locus_tag="L1V16_001280"
     CDS             11980..13119
                     /locus_tag="L1V16_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HBN1275629.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            13112..13912
                     /locus_tag="L1V16_001281"
     CDS             13112..13912
                     /locus_tag="L1V16_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1275630.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            13912..14739
                     /locus_tag="L1V16_001282"
     CDS             13912..14739
                     /locus_tag="L1V16_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1275631.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            14717..15451
                     /locus_tag="L1V16_001283"
     CDS             14717..15451
                     /locus_tag="L1V16_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1275632.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            15551..16417
                     /gene="rfbA"
                     /locus_tag="L1V16_001284"
     CDS             15551..16417
                     /gene="rfbA"
                     /locus_tag="L1V16_001284"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBN1275633.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            16431..17003
                     /gene="rfbC"
                     /locus_tag="L1V16_001285"
     CDS             16431..17003
                     /gene="rfbC"
                     /locus_tag="L1V16_001285"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBN1275634.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            17025..18053
                     /gene="rfbB"
                     /locus_tag="L1V16_001286"
     CDS             17025..18053
                     /gene="rfbB"
                     /locus_tag="L1V16_001286"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBN1275635.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            18151..19002
                     /gene="rfbD"
                     /locus_tag="L1V16_001287"
     CDS             18151..19002
                     /gene="rfbD"
                     /locus_tag="L1V16_001287"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBN1275636.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            19036..21069
                     /locus_tag="L1V16_001288"
     CDS             19036..21069
                     /locus_tag="L1V16_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275637.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            21113..22393
                     /locus_tag="L1V16_001289"
     CDS             21113..22393
                     /locus_tag="L1V16_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HBN1275638.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            22603..23409
                     /locus_tag="L1V16_001290"
     CDS             22603..23409
                     /locus_tag="L1V16_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1275639.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            23421..24641
                     /locus_tag="L1V16_001291"
     CDS             23421..24641
                     /locus_tag="L1V16_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1275640.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGVNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            24631..26217
                     /locus_tag="L1V16_001292"
     CDS             24631..26217
                     /locus_tag="L1V16_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBN1275641.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            26256..28394
                     /locus_tag="L1V16_001293"
     CDS             26256..28394
                     /locus_tag="L1V16_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1275642.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(28762..29745)
                     /locus_tag="L1V16_001294"
     CDS             complement(28762..29745)
                     /locus_tag="L1V16_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBN1275643.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            30123..31514
                     /locus_tag="L1V16_001295"
     CDS             30123..31514
                     /locus_tag="L1V16_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBN1275644.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            31530..32570
                     /locus_tag="L1V16_001296"
     CDS             31530..32570
                     /locus_tag="L1V16_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1275645.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            32589..33674
                     /locus_tag="L1V16_001297"
     CDS             32589..33674
                     /locus_tag="L1V16_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HBN1275646.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            33707..>34003
                     /locus_tag="L1V16_001298"
     CDS             33707..>34003
                     /locus_tag="L1V16_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBN1275647.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYP"
BASE COUNT        11019 a         5827 c         6703 g        10454 t
ORIGIN      
        1 ttttttgcat gtgtgcgaaa gtatactcaa gcccaatcgc catttcggaa aatcggtact
       61 gtagagccat cttcacggat tccgtcgata tccatcttgt cagatcctac catgaaatct
      121 acgtgggttt gacttctatt caatccagct tctgctaatt cttcatcgga catttctgta
      181 ccgcctttca cactgaaggc ataagcagaa cctagtgcta agtgattcga tgcgttttca
      241 tcaaataatg tattgaaaaa gatgatgcca gattgagaaa taggtgaagg gtcaggtaca
      301 agtgcgactt ctcctaaacg acgcgcacct tcatctgtat caagcagttt tgctaagaca
      361 tcttctcctt gttcggcaga aaaatcaaca acttttccat ctttaaaagt aaatttcata
      421 cccgagatga tggtgccagc ataactcagt ggctttgtac ttgaaatgta accatctact
      481 cgatgactgt caggtgctgt gaacacttct tccgtcggca tatttgccat gaatttttct
      541 ccacgagcat tatagcttcc agcgccttcc caaagatggt ttttaggcaa tccgataatg
      601 atatctgtac cgggagcagt atagtgaagg gcagaaaatt gttctcgatt caattcttct
      661 gctttttttg ctaatttttc atcatgcttc ttccatgcta agacagggtc ttcttcatag
      721 acacgagtcg ttttgaaaat ctgatcccat aatgcctcaa cttgtttttc ttctggcagt
      781 tctgggaaga cttttgctgc ccattgttta ccagccgcag ccacgacagt ccaactgact
      841 ttatttgctt gagttgcctt gcgtaaattc attagtgctt tgccattcgc tgattgataa
      901 gacgctactc gatggctatc tacaccagca aatgcatcgg gatcggcaga aacaacgctg
      961 atcctgcttg ctcctttttc aagccattca tccgcttgat cgattttaga ttgtggtaca
     1021 ttctcaatac gatccgttgc agcatgtaaa agaaattctc tttggatctg gtcgtcagtc
     1081 cattgaacga taacctcagc ggctcctagt ttataagctt cttgtgtgat caatcgagca
     1141 aggggtgcct gttccacgct gatctgtaaa acaactgtgt gtcctttttc tgtggctacg
     1201 ccagtttctg caattaagcg tgcatatttt tttagaagtt cattaaaatc agataacata
     1261 ataaaaattc ctcctcacca ttttttctgg taactattag catgatacca tttaattatg
     1321 attcaaacaa tgaggcttta aataaaaaaa ggaggttatt tttttaaggt taagtttcat
     1381 gatatatgtt actacttgct atttcagctt gtgaagaaaa tcaaaaacta attttgcata
     1441 tcaaaaaaaa catgttacaa tgaaattaat caatggtgga agcgttataa aaaaattaag
     1501 gagattaaaa aatatggcaa gaaaaaagac gattactaga gaacagattt tggcagctgc
     1561 ttatgaagta gctgccaccg atggatttac acgatttact gcgagaaaca tcgcgaacaa
     1621 aatgaattgt tccacgcaac cgatttatct tgagtttaaa aatatggatg acttgagaca
     1681 agctcttttt gagcagatct atgatcattt acaatatgaa gtgttcactg ttgagcatac
     1741 agggaatacg attatcgatc ttgcttttaa ttatatccat tttgcaagaa gagagaagaa
     1801 gttgtatcgt tcactgtact tagaagaata tggtggagga aaagagatgc agaatttctc
     1861 ttatacttac tttgtgaata cagtgaaacg cgatccagct tatgtgaatc tttcagaaga
     1921 gcagatcgaa tctttgtata atgggacatg gatcatagct actgggatcg cagctttgat
     1981 gtcttcaagc atcatccatc caactgatga acagattgaa aagatgatcc aagacagtat
     2041 agatgctatc ttgaaattca aagaaccaat cgaaatcgat tgaatatact caaaagttcc
     2101 acaaatcagt aggtaacaag agatgtgtca aaataaggaa aagttcgttt ttcttacagc
     2161 gtatgcattt ttaactcccg aagaactctt ccatgaatgc aatgaataaa agagccatac
     2221 agattgaata aatctggatg gctcttttat tgcaagtata ttaaattttt gcgactagtt
     2281 ctttagcgaa agcttctaaa ttttcgatat cttcttcttc agcattcaga tccactttaa
     2341 cattttcggc tccttttgat gcgcctgttt ttgcaaaagc agcatcgaaa tcatccaccg
     2401 atttgcagaa ttcatcgtaa aaagtatcac cagatccgca gacaccgtaa atttttccca
     2461 atagatccaa ttcttgcaag tcttcataaa agtctacgat ctcatcaggc agatcgccat
     2521 catcgtatgt ataagtagct actacgcaaa tatctgcctc ctcgaattca tctgcatcta
     2581 cttgggtaca ttcgttgatt tcgacttcga tatccagatt ttcaaatgct tctgcaacaa
     2641 tatcggcgat ttcttcagtg tttcctgtca tgctagcata tacgattttt gctaaagcca
     2701 tgatgtgcct cctcgtttat aattatttaa caattatgaa ttataccaaa acatcattga
     2761 aaagaaaata aaacctagag acacctgggg aatgtcattt ggctaaatgt atgccgctat
     2821 gttaaaatga gagggatttg taaaaaggag acgaaaatat gattacttta aaatcagcac
     2881 gtgaaattga aatgatggca gaatctggag ctttattagc agatgtacat aaaaatctgc
     2941 gtgattttat aaaaccagga atcacaagtt gggatattga ggtatttgtc agaaactata
     3001 tcgagagtca tggcggaatt gctgcgcaaa ttggctttga agggtatgaa tatgcgactt
     3061 gtatcagtat aaatgatgaa atttgtcatg gattccctcg taaaaagcct ttgaaaaacg
     3121 gtgatttggt aaaagtcgat atgtgtatcg atttgaaagg cggcatttct gattcttgtt
     3181 gggcctatgt agttggagaa tctacacctg agatcgaccg attgatggaa gtaacgaaga
     3241 aagctttgta catcggtatt gagcaagcac aagtagggaa tcggattggt gacatcggtc
     3301 atgctatcca aacttatgta gaaggcgaaa atctagcgat cgttcgtgat tttattggtc
     3361 atggcgttgg tcctacgatt catgaagaac cagcagttcc tcattacgga gaagctggaa
     3421 aagggttgcg gttgaaagaa ggcatggtta tcacgatcga acctatggtt aataccggaa
     3481 cttggaaaat gaaaatggat cctaacggct ggactgcgta tacaagagac ggcggacttt
     3541 cttgccaata tgaacataca ttggctatta ctaaagatgg tccaagaatt ttgacatcac
     3601 aaggagaaga aggcacttat tgatctatcc agtcaatagg tacgggagag gtacatgaaa
     3661 gtttggaaca aaataaaaca aaatgaaaat ctgatgcgct ttattgagac gactcaaaag
     3721 cgcatcactg attcagaaat gagtacgacc tctgtcgtcg ttgcttatta tttactcttg
     3781 tctttatttc cattgattat tgcttttggt aatattttac cgtttctcca catcgatcaa
     3841 gagactgtac tgacctattt acgagaagtg attcctgaga ccgtttacca gtttatcggt
     3901 cctgcaatca aagacctttt gacacaaagt tcaggaggct tgttatccgt ttctgcatta
     3961 gcggctttat ggtctgcaag tcaaagtatc aatgctttgc aaattgcgat gaataaagcg
     4021 tatggcgtag aaaatagaaa aaattttttg atcgtccgtt tcttctcact aattgtcatt
     4081 gtcttgttca tgattgctat tagtggggta actatcgttc ttgggttggg acagctgatt
     4141 ttggatgcta ttcagccaat cgtacaaata cccgtgaact ttatcgatca gttccaaact
     4201 ttgaagtggc caatcacatt ggtagcttta tttgtcatca tgttcttgat ttatttaatt
     4261 gtccctaatg ctcagttgaa gttgaagacg atcattccgg gcacgatctt cgctactgtc
     4321 ggctggatgc tgttatcaca agtgtttagt atctatgcta ggtattttgc aacgaggatc
     4381 agcggttatc agatcatagg aagttttatt gtactcatgc tttggcttaa ttttgctgct
     4441 acgatcatca ttttgggcgg aatcatcaat gcagttgttc aagaatacgt gacgggtcat
     4501 caaatcaaaa aacgtcgaga tccaagccga aaatggttca ataaattgaa aactaaattt
     4561 tctcataaaa aaaagtagaa acaagagttc ttattgtaaa tttatatcag taatttattt
     4621 gaaattttat atctaatttt caattatccg cataaacact atacattcaa gcattttgaa
     4681 gtatagaaaa acactcatct taccacgaat ttaccacgat tgaatgagcc ttgatatgac
     4741 cgtaaaacta ctaagggaga tagcacgaaa ctgtgtatct cccgattttt ttatacagtt
     4801 gattacttca ctccgatttc aaatttcaat attgctttca tcatgtctgt atgaatttct
     4861 ccttttagtt cttcatcaac ctgcataatg attttaccac tttcagagtg gtaaaaagga
     4921 cgcaagcata atttagaaat ataaccgtca taaaacttca aaatctcttt aactgccatt
     4981 tcatctccgc ttgacgcttt gcaaatcaat tcaaaagagg gatagccata atctttactc
     5041 atttctttac ttcctttcgc tcaaaagcat ttttaacttc cttagtcctc tagttcttct
     5101 actgcaaata gcagaacgtg atacatggta cagttctgaa atttctctgt cgttcattcc
     5161 ttgaaaataa cgtaataaaa tcgcactacg ctgtttttct gacagtctat gtaaaactgt
     5221 accaagtgtt tcatcagata cataaattgt aaagtgcaag actttaaatg atacacaatc
     5281 ataaaaacag gtatcaatcg ttccacgttc aacttgtttc gtttcggcta tttcacaaaa
     5341 caatacttca cgtttagaat gtcttgcaag ctgtctgttt cgacttttca ctttgttctt
     5401 aatgacaatc agcattaaag aattgaactg taatctgacg atatgctcga aagaagatgt
     5461 cctcataatc tcaccccctt tctgctaatg ctgaaatata taaacggaat accgtttata
     5521 ccctttagaa atacagaaaa atggtaagaa aaaagcccac acaaaacata tatttgtgcg
     5581 agccttaaat actgcaatat tactctttct tttataacac tatcctttta gcagatttca
     5641 aattttcttt tatatattgt ttttagccta acatactatt taaccccttg tattatatct
     5701 ctaacttttg aaaaattctt tttgaatata ttgaaatcat gattgaagca atagaagcta
     5761 caaacataac aacccatgtt tcttgtataa atacatcgaa taaaataccg taaaccattt
     5821 gtccaatagg ttgaccgcac atagcaactg ctaccagcgt agccattatc tttcctacta
     5881 attgcggtgg tgtttgtgtc tgaacaagag tgtaaatttg aacaacaaac atagtagata
     5941 cacccatagc cacaaagcac atcactgtaa ctacccagta ggaaactatt gcaggcaatt
     6001 ctaaaaatag cgaaattccc ataagtaaaa cagaaacaga acaaataagt aacaaggtat
     6061 aaaggttttt tagttttaac tttgaagcaa caagagctgt taaaatacca ccacataaac
     6121 cacctaatga taatgctgat tgtgaaaaac catatagtgt atctggcatt tttaaaactt
     6181 cagaaattaa gataggcaga ccaacaatta aaacagcact taaaaccaaa ttgaaaatgc
     6241 aaaccaaaaa gattacggat ataaaaatgg gtttctcctt tttcaaaaag gtataactat
     6301 cttttaaatc gtttttagca actgcaatta cacctacttc acgaggtctt ttttggtgtg
     6361 gaatatggat aaaaatttcc ataatggctg aaaaagtaaa acatataata ctaacaatta
     6421 aaatgggatt gataccataa aattgaaaaa ctactccgct tatagctggt ccgataaagt
     6481 ttgctaaagt atttacttga tttattatag cattaccgac ggtaagttta tctgatgata
     6541 ccaatagagg aatacttgct tgtaccgctg gttgatatgc accagaaata ccataaagta
     6601 acatcaaagc aacaataaac aaaggtatga taggaatttt tcccaatgac aaataaaata
     6661 ctaaaattat gattgctgtt acaaaatcta gtatgaccat aatgtttctt ttatttgtcc
     6721 tgtcagcaat aataccacct accagcgaca aaataaccat aggtaaaaaa gagcaggctg
     6781 tagcaatacc aaacaaagct gatgaaccag tttcttttaa caaatagtac ggtaatgcaa
     6841 atcgtaggat agcgtttcca aataaagaaa ttatctgtcc tataacaaca agtataaaat
     6901 cacgattaaa aagttttttt tctgcttgca taaaatctct cctttttatt taatcaaaca
     6961 gaccgtcggt ttatataatg gtttaaataa actgctcttt tatagagcag tctatcgtat
     7021 agggataaca aatacagtta tttacaaaac tgtataaatg cagaaattgt ttcttcgtct
     7081 aataatgtgt ctatgcctat tccatttaaa agggcattga atgtattgca acgtttttcc
     7141 ataccctctt tatccgtcat ttcaactaat gggttgagcc atacattact taataccatg
     7201 ataacttctg caatttcatg tgaattttca atctccaaag acttatcctt gataccttgt
     7261 tctaaaacgg gttcaacaaa ttcaggtact acaatttcat acatttgttc tatttgcata
     7321 gcaagaaaac gaggattgtt taatagttga ggagaaactg tcaataaaac gctttggtta
     7381 gaattgaata ccgctgtctt aaatatttct cttaactttt ctaaaccgtt taaactatcg
     7441 ttatctctaa ttttagcaaa tattactgca ttttcatttc caattctttg aaaaattgct
     7501 tttaaaatat cttcctttga atcgaaatga tgataaatag cacctttaga aagttttgtt
     7561 tcattgataa tatcttgcaa tgatgtgtta tcatatcctt tttcacaaaa catttttgta
     7621 gaaacatcta aaatgagttt tactgtttct tctggatatt tatttcgtgc cataacttac
     7681 ctccaataca aaccgttggt ctgattaaag tatatcttag tattttatgc ttgtcaatat
     7741 aaagacttgc aattttataa aaatgcagaa tgcaagcctt tttcatttat tctacaatct
     7801 tccagttgct ttccttatgc ggtgtcaatt catactgtga tacctgcgtt gcctttgcct
     7861 gatttaccac aaatcagatt ttatcccttt cttcctcttg attgcccaca acagaaaaga
     7921 aaaagccctg tcaagagctt tgccaccatt ggtggtgctt tgcactcttg atcgggcttt
     7981 ttgtttgctg tatcttctcg caagaggaaa aaagttactc gtcctcatca tcaaaattgt
     8041 tattccttaa tacttctcgt aacagttcca tatcttcttt tgagttcggg tttatcattt
     8101 tcacgacttg ataaggtgtc ttatacttat gtccctctat gctttcccca aacatatcca
     8161 tactgtataa atcatcatag cggtctaata atttttgaaa cttcaaatgc tggataaatt
     8221 ctttgattgg gtaaaggtcg gacgcttcaa tgcttttccc gttgatatag tctgtaatat
     8281 attcccgtaa cttttctaac tcatattcca gccattcttc ctcgctgtca aagaagttat
     8341 catagtgtcc atgtttcagt tctgcattta gacgttcttc ggctcttaaa aactgacaga
     8401 cttccttttc agattgattg acatacttcc attctcccga caacaattca ttgggcgtaa
     8461 cgtccagcac ttccattatc ttttccagcg tttcataggc aggatagttc aaccctcttt
     8521 caatcttgga aaggctctgc atattgatac cgattttgtc cgcaagttcc tgttgtttca
     8581 ttcccctaaa ttttcttatg gtctgtatat tatttcctaa atggcttatt ttcattgcat
     8641 aaccctccat atctcgttat atcttcgcta ttataagtct atcatgctta atatgatttg
     8701 taaaggcaaa aaaagatatt gacaaataag catataagaa ttactatgtt cttgtaatcg
     8761 aataagcaca atagaatgaa atataaaaac attcaaaaag aaatacctat ctgattaaat
     8821 ccgtagatat gaatatcggt tgaaatggaa cttgttagaa aaggcaaaac agaacttgct
     8881 gacaaagtat ttctgacacg gtggcggaag cctctcaggc ttaccgccat gacaccttgt
     8941 gtcaagggga agaaatgctt tgtcggctgg cgagcctgcg agccttgtct gtgcccccgt
     9001 tatctaacag gggggcacta tttcacaaaa gacaagtcaa aaaccataca cccccaaacc
     9061 tgtgagtagt aatgagaggt tttaagaaga tagtacatat cacacttttt gaaaggtggt
     9121 ttacaggtat ttcaaggcta ttgtgggatt ggaggaatac aatgaacaat ttagaatttg
     9181 cacttgaaat gaagaacaaa cgtcttgcca gcggtctttc acaaggagaa cttgcaagtc
     9241 ttacccatgt atcaagatat agtatcaacc gctttgagaa cggaaaagct aacgccagca
     9301 aggaaacaca gaacattatc ctgcgttgtc tgaattacta tatctgcgat aagccttttt
     9361 atctgctcgt tgattatctg tctgtccgtt ttccaacgac tgacgcattg gaagttatcc
     9421 gaaaggtgct tggcatgaaa gcagattatt ttatccatta tgactatggg tattatggct
     9481 ataaggagca ttatgcttac ggggaaatca aggtcatggc ttctgatgat gaacacatgg
     9541 gcgtattttt agaattaaaa ggggcaggct cacgcaacat ggaatatgtc ttacaggcac
     9601 agaacaggga ctggtattca ttcttaaacc gctgtcttga ctgtggcggt gttatccgac
     9661 gttttgactt ggcaatcaat gatatgtgcg gtctgctgga tattcctgtg ctatctgaaa
     9721 aatacagaaa tggtggtgcg gaatgtcgct gtaaaaacta tgaaaatgta caaggtggaa
     9781 aattaagcgg aaaaaaccgt aatttagcaa gtacccttta tatcggctca aaggcaagca
     9841 caaaatattt ctgcctgtat gaaaaacaaa aggaacaggc aacgaaaaag aaacataccg
     9901 atattatcaa ccgttttgaa attcgtctgc gtgacaaaaa ggcggtacag gcagttgaag
     9961 aactgttatt gacgtataac cctcatgggc tggtgtttta tctcattacc gattttgtgg
    10021 aatttcctga ctatccattg tgggagatat tcatttccca tgacagttta ccttttgaaa
    10081 tgaaccctgt acctgtcaat atggaacgca ctctgcaatg gctggaaaga caggtcatgc
    10141 cgtcaatcgt gatgatagag gaaatcgaca ggctgacagg ttcaaactac atgaaaatga
    10201 ttgatgaatg tacccacctt tctgaaaaac aggaaatgct tgtggaacag atgtgtacgg
    10261 acatatcaga cgtaatcgaa agtgaggggg tgttttatga gtaatacaca ggatattccc
    10321 gtatgggaaa aatacaccct taccattgaa gaagcgtcaa agtatttccg cattggagaa
    10381 aacaagttaa gacgattggc agaggaaaac aaggacgctg gctggctcat tatgaatggc
    10441 aaccgcatac agattaaacg ccgacagttt gaaaaggtta ttgataaatt ggacgcaatc
    10501 taatgcaaat gagccttgta tgtgttatga tgaacacaag tcatatcaag gctctttcca
    10561 acaaggaaag gagcagacac catgaaagaa aaaagacggg ataacaaagg tcgtatcctg
    10621 catactggag agagccaacg aacagacgga aaatacttat ataaatatgt agacgcattg
    10681 ggaaacacaa aatatgtgta tgcttggaga ttgacaccca cagacccgac accaaaggga
    10741 aaacgggaaa aaccctcact tcgagaactg gaacagcaga taagacggga tattgaggac
    10801 ggtatcgaca gcacaggcaa gaaaatgacg ctttgccaac tctatgccaa acagaacgca
    10861 cagaggacaa atgtgaagaa aagcacacag aaacaacggg aacaactcat gcggttatta
    10921 aaagaggaca agttaggtgc taggagcatt gatacgataa aaccctctga cgctaaagaa
    10981 tgggcgttac gcatgaaaga caaaggcttt tcctacaata ccattaacaa ccataaacgc
    11041 tcgttaaaag cgtcattcta catagccata caagatgatt atgtgaggaa aaaccctttt
    11101 gatttcaagc taagtgaagt catagaaaat gataccaaag agaaagtcgc attgacagag
    11161 gaacaggagc aagccttatt gtcatttatt aagacggaca acgtgtatca caagcattat
    11221 gatgatgtgc tgatactgtt aaagacagga cttcgtatct cggaactgtg cggactgaca
    11281 gtagccgaca ttgatttcaa gaatgaagtt gtgattatcg accaccagtt actaaagagt
    11341 aaggaacagg gctattatat tgaaacgcct aagacgaaaa gcgggataag gcaagtgcca
    11401 ttaagcaaag aaacgataca ggcatttcaa cgggttatca acagccgacc aaagataaag
    11461 tcgatagagg tagacggaca cagcggtttt gtgtttatca atccgaaagg taatccaaaa
    11521 gttgccattg attataacgc cttatttatc cgtatggtaa agaaatacaa caagcaccac
    11581 aaggacaatc ccttgccaca tattacaccg catacgctac gccatacatt ctgcacaagg
    11641 ctggcaagca agaacatgaa cccgaaagat ttacagtata tcatggggca ttcaaacatc
    11701 agtatcacaa tgaactggta cgctcatgcg tccatagata ccgcaaaatc agaggttcag
    11761 cgtctaatcg catagaagta tttaccacga ttttaaccac gattgacagg gaaaatataa
    11821 gaagatagac ctagatatgc gaggtttacc acaaaagcaa aatgcccgta gagccgataa
    11881 aataaggctt tgcggacatt tgagaagata taaaaagata gtcaaaaaga catatataat
    11941 ttataataat tatgactctt aattaaagta ggtgcccata tgcttgtttc ttttagtatg
    12001 gttataagat tttttctgac aattttatta tcactgatat taacacctgt attcaaaatc
    12061 atttcagtac aaacaggtat ggtcgacaaa ccaaatgaaa gaagaataaa taaagttcca
    12121 atgccttcag cgggcggact gcctatcttt atttcatttg ttatatcgac tttattctta
    12181 ttccgtaaaa ttatccctca atcgtatatt gtaccgatct tgattgcttc tttagtaatc
    12241 atagtcacag gagtgctcga tgataaatat gagctgacac ctaaacaaaa aagtataggg
    12301 atcttgattg cttctcttat tatttatttt gtagcagata tacgtattga ttccttcacg
    12361 cttcctttta ttggatatat ccaactaggc tggcttagtt ttcccgtaac gattttttgg
    12421 atcttcggta tcacgaatgc ggtcaatctg attgacggtt tggatgggct ggcggcaggg
    12481 atttcattga tcggtttaat tacgatagga atcattggat attttttcct ccatgcttct
    12541 acagtgtata ttccagttgt tattttctgt cttgtagcaa gtattatcgg tttttttcct
    12601 tacaattttt atccggcaaa gatttattta ggcgatacag gagctctatt cctagggttt
    12661 atgatggccg tcctttcact acaagggctg aagaacgtga cttttgtttc atcgatttct
    12721 ttgctgatcg tcatgggagt gccggtaaca gacacgtttt ttgctatcat taggagaaaa
    12781 gcaaaccgtg tttctttttc tacagcagat aaaaaacatc ttcatcaccg actaatcagt
    12841 ttaggcttta ctcataaagg tgctgtcctg acgatttatg cgatggcttt gatgttttct
    12901 ttcacagcta tggtcatgaa ttatactgga agaatcggaa cgatcatatt gattattgcc
    12961 atgttgtttg ctgcaatttt attatttgaa ttgattggtc tgatcaatga gaaacatcag
    13021 tttattttaa aaacattgcg atttttaggg aataaagagt accgtacgca agtaaaacag
    13081 aaatatttga agaaatggaa ccgtcatata gatgaataac aaattaaacc agccgatcct
    13141 tattagtatt gtgacggcaa acagtgataa aatttttcgg acactagata attttatttc
    13201 aactgtaaaa gatgaaacag cagtaaaaat ccgaattttt gacaacaatt cacttcccga
    13261 gtacaaaaaa agactaacag agtataggaa atatccctac atcgatatct attttcatga
    13321 tgaaaattcc ggatttggtt atggacataa tcacaatctg atagctagcg attctcgcta
    13381 tggcattatt tgtaacccag atattttagt ggatgaagag acagttacag cattggtctt
    13441 gttattgaaa gaacatccgg aatgtgcgat gttagcacct aagattctta atgaagatgg
    13501 aacaactcag cacctcatcc gtgagcagct ggctgttttt gattacgttt tgcgctttgt
    13561 gcctttcaaa tgggtcaaaa aaaagtttga caaacgactg gctgtgtttg aatgccgagg
    13621 attgcctact gatgctaata gttatgtacg gatgatctca ggtagtttta tggtagctga
    13681 tattgataaa tttaaagaga taaaggggtt tgatgagcgt ttcttcatgt actttgaaga
    13741 caacgacttg tgtttgagtt ttgaaaaagc aggttacaag ttattgtaca caccctttta
    13801 tgcagttatc catttttacg ggaagggtgc gcatcgaaat gcaaaactgt ttcgcgtgtt
    13861 tttgacttct atgatgaaat ttttcaataa gtgggggtgg cgttttttct gatgaaacca
    13921 gaaatattag tagtcgttgt gctttatcag caactattca gtcaatctcc agcttatgga
    13981 ccattaagca aagcacttag cgaaaagcaa attcagctta ttatttacga taatagtcct
    14041 caaaggcagc aaaatgagct gtttgaaaaa gaaaatatcg tttatcatca tgatccgcaa
    14101 aatcctggtt tagcggtggc ttataatttt gcgttgtctc aagcagatga aggaacacgt
    14161 tgtctcgtca ctctggatca ggatacgagg ctagtcgacg attattttga actattgcgt
    14221 aaagtaacct ttacagatga atgtgttgct gcagttccga tgattttttc tgggagccga
    14281 caagtttctc ccctatattc agatcgttat atcaatcgta cagctcaagc agtagaagtt
    14341 gaaggcccaa cagctgaacg aatcatggca atcaattcag gtgttgcctg gtctgtcaaa
    14401 tttctaaaaa agattggcgg gtttaatcct gctttttctt tagatttttt ggatcattgg
    14461 ctgttttgga aagtggatca gttggaaaaa actgtggaga tccttcctgt acgaatggaa
    14521 catgatcttt cggttttaga ctatgaaaaa gtttcaagta atcgataccg ttctatttta
    14581 caagcagaaa atcgatttta tcatgaatat gatcaaaggc atttatccag tcaccgacga
    14641 caattattgt taagaacagc taaacagttc ttgaccgtca aaaaccggca tatctggcgg
    14701 atgactttgc gctcatatgt taagaattgg aaggtgtgaa ttcgtgcgtt cggtttgtat
    14761 agctaccttt aatggaggca gatatttaag agagcagtta gatagtattt tatctcagct
    14821 ttcagcagaa gatgaagtag tcatttctga tgatgggtca gtagatgata catgggatat
    14881 attaactgaa tacgcagaaa aagataagcg aatccagctt ttttcggggc ctcgtcaagg
    14941 attgatcgct aattttggtt atgcgatcca gcagacgaaa ggagatctaa tctttttggc
    15001 agaccaagat gatgtttggt tggagacaaa agtgaaaaag atcactgact attttgagca
    15061 gaatccggat cagctagtag tagtttctga tttaatcatt gtggacagcg agctgcaaga
    15121 gatccatgat tcgtattttt cgtttcgaaa ttccaaagaa ggatggctta ataatgtgat
    15181 aagaagtcac tatattggtg ctggtatggc tttccggtct tctttaaaac ccgatatttt
    15241 gccgatcccg tcagaagtgc cgatgcatga tatgtggatt ggtttgctgg gaggaaagaa
    15301 gactgggttc ctaagagaac cgttaactct gtaccgaaga catgatttaa acgcgagtga
    15361 gattgaaaca cattctaaat tacggcaaaa aatttcttgg cgtgttcatc tgattacggc
    15421 gttgatcaaa cgaaaatggt ttaaacgttg ataaaagatg tttaaatcct taatatttcc
    15481 atgacaaata taacaattga tgagataata acaaagtgaa atttgaaatc aaaaaggaga
    15541 gcagatatcc atgaagggaa tcattcttgc tgggggcagc ggaacacgtc tgtacccttt
    15601 aacaaaggca acatcgaaac aattgatgcc gatttatgac aaaccaatga tttattatcc
    15661 aatgtctact ctgatgttgg cgggaatcaa agaaattctg attatttcaa cgccacaaga
    15721 tacaccacgt ttcaaggaat tatttggaaa cggaaatgat ttaggactgc agatcgaata
    15781 tgcagtacaa gaaagtccag atggattggc acaagcgttt atcattggag aagaatttat
    15841 tggagatgat agtgtctgct tggtattagg ggacaatatt tactatggtg gcggtctgtc
    15901 taaaatgttg caacgagcag cttcaaaaga tacaggcgcg acagtatttg gctatcatgt
    15961 caatgatcca gaacgctttg gtgtagtaga atttgatgag aatatgcaag ctttgtcgat
    16021 tgaagaaaag cctgctcagc caaaatcaaa ttacgctgta actggccttt atttttatga
    16081 caatgaggta atttctatcg ctaaaggtat caaaccttca gaacgtggag aactagagat
    16141 tacggatgtc aataaagcat atttggataa aggaaaacta tccgtagaac ttatgggacg
    16201 cggatttgct tggcttgata caggaacaca tgaatcattg cttgaagcat ctacctttat
    16261 cgaaacaatt gaaaaacgtc agaacttaaa agtggcttgt ttggaagaaa ttgcttaccg
    16321 tatgggctac atcgataagg aacaattgct ggcccttgca cagccattga aaaaaaatca
    16381 atacggtcaa tatttattga atttggccgc tgaataagga gtccttacag atgaaagtaa
    16441 cagatacaaa attaacagat gtcaaaatcg tagaaatgga cgtctttggc gatcatcgcg
    16501 gtttcttcac agaaagttat tcaaaagcaa aatttgcaga acatggattg aaatatgact
    16561 ttgttcaaga caaccattca ctatcagctg aagctggtgt ccttcggggg cttcatttcc
    16621 aaaaaggaga agctgcacag acaaaattga ttcgggtagt cactggagca gttttagatg
    16681 tagtagtgga tatccgcaaa ggtagcccga cttatggtca atgggacgga tttatcttat
    16741 ctgaacataa tcatcgacag ttgcttgtac ctaaaggata tgcccatgga ttcgttactt
    16801 tgacaccaaa tgtgaacttc ctttataagt gtgataatta ctataatgca gaagcagatg
    16861 ggggcatcgc atttgatgat ccagatttag cgattgattg gccaattgat ccatcaagag
    16921 cgattatgtc ggaaaaagat caccgtcatc cgacattaaa agaatttgaa gcagaaaatc
    16981 catttgttta cggagaaatc taagaattaa ggagaaattt tcttatgaaa aacatcattg
    17041 ttaccggagg tgccggattc atcggctcta atttcgttca ttacgtggta aacaatcatc
    17101 cagaagtgca tgtcactgtt ttggataaac tgacttatgc aggaaacaaa gagaacttgg
    17161 ctggacttcc tagcgatcgc gtagaattgg tcgtaggaga tgttgcagat gcagaattag
    17221 tggaccgtct agtaaaagaa gcggacgcag ttgttcatta cgcggcagaa tcccataacg
    17281 ataattcatt aaaagatcct ttcccatttg tacaaacgaa tatcattggt acgtatacac
    17341 ttttagaagc ttgccgcaag tatgatgtac gctatcatca cgtatctact gacgaggttt
    17401 acggcgatct tccattacgt gaagacctgc caggacatgg ggaaggcgaa ggagaaaaat
    17461 tcactgcgga aacaccatat aatccttcaa gtccatattc ttctacaaaa gctggttcag
    17521 atctgttagt aaaagcatgg gtgcgttctt ttggcttacg tgcaaccatt tcaaactgtt
    17581 caaacaacta tggtccttat cagcatattg aaaaatttat tcctcgccaa gtaacgaata
    17641 tcttaagcgg tattcgtcca aaattatatg gcgaaggaaa gaatgttcgt gactggatcc
    17701 atacgaatga tcattcttca gcagtgtggc tgattttgac gaaaggcaga attggcgaaa
    17761 cctatctgat cggtgcagac ggtgaagaag ataataagac cgtgatggaa ttgatcttag
    17821 aaatgatggg tcaaccaaaa gatgcgtacg accatgtaaa cgaccgtgca ggacacgact
    17881 tgcgttatgc aatcgattcg acaaaattac gggaagagtt aggatggaag cctgagttta
    17941 cgaacttccg tgatgggttg gctgacacga tcaaatggta cgaagaacat gaagactggt
    18001 ggaaaaaaga aaaagaggcc gttgaagcag catatgccaa aaatggacaa taatacagag
    18061 aaaatgtcac tgtattaatg gaaaaacaca tgtgaggcag gcgctcgcct gtctcttttt
    18121 taaaataaaa atcaaggagc ggataatcat atgtttttat taactggagg aaatgggcaa
    18181 ctaggtacag aattgcgcca tttattagat gaaaaaaatc tgcaatatgt ttcaacagat
    18241 gcaaaagact tggatatcac agatgccgag aaaacaatgg cttacatcac agaattaaaa
    18301 cctgatgtta ttttccattg tgcagcttac acagcagtag ataaagcaga agaagaagca
    18361 aaagaattag atgagaagat caatgttgat ggtacaagaa atgtagcact tgcagcaaaa
    18421 gctgtgaatg ctcaattcgt ctatatcagt acagactatg ttttcgatgg aaaaaacaaa
    18481 aatgtagaat acgaagtaga cgaccaaacg aatccactaa atgaatatgg tcgtacgaaa
    18541 ttattaggcg aaaaagcagt agaagagatt ttagaagact attatatcat acgaacttct
    18601 tgggttttcg ggatctatgg acacaatttc gtcttcacga tgcaacgcct agcggaaacc
    18661 cgcgacaaac tgactgtagt aaatgaccag tttgggcgac caacttggac acgtactttg
    18721 gcagaattta tggtatatgt catcgaagaa aaagcaccat ttggtattta tcatttgtcg
    18781 aacgaaaata gctgttcttg gtatgaattc gcaaaagaaa tattgaaaga tacagatgta
    18841 gaagttgcac ctgttacgtc agaagaattt ccgcaaaaag caacacgtcc gcagtattca
    18901 gtcatgagcc tgaaaaagac agaagagtta ggatttgtca taccaacttg gcaagaagca
    18961 cttgcgcaaa tgctggaagc tgccaaaaaa atgaataagt aatttccttt tatcaaatag
    19021 aatttggagc atgatatgga aaaacaaaca agaagtgcac gacgaaaaga aaagccaaaa
    19081 gcgaaccagg cagattcgaa tttggtgctt gacctgtttc taaaactccg ctatcttatt
    19141 ggcgttttag tcatcgtggt catcgttact tttaatttaa acggaagttc acttggtgtt
    19201 tgggataaat atgtgtcgca aagagacgat gggaaaaaaa ctgatgtgat ttttggacag
    19261 aatcgggaag tgcggtcaga cgaatggctg gtgcagacac ctttttacct ctcacaagct
    19321 gaagaggact ttccgttggt gaacgaggat tattcattaa acggacaaaa catgatcatt
    19381 gcgtataatt ctcctgtaaa ggatattacg gttatcggaa aaccattcaa ctggggattc
    19441 tttttcctcg gaagagatcg aggactttcc ttttattggg cgatgaaatt agtcgtcatg
    19501 gtcttgcttg gattcgaagt actgatgata ttaacgaaga gaaaaaaagc tctatcgcta
    19561 atcggtgcat ttgcgctgac attttctcca gcagtccagt ggtggttcat gcaacatgtg
    19621 ggcgatttga ttttctttac tttgggactg atgactgctt tttatcatta tttctacaat
    19681 catgataaaa aatggctacg aacgttgatg atgcttttgg tggttatttt cggtattggg
    19741 tttattttag tgatttaccc agcccatcaa gtgatgctgg cgtacttgct gattttttat
    19801 tttgttggcc tgcttattta ctatagcaag aaagtttcat gggatctgtt ggatgtagtg
    19861 ttgattggag gggcagtttt atttattggc ggagtcatgg ttcatttctg gctaacgtca
    19921 aaagacgcat tgttagcttc tttgaatacc ttatatccag gaaaacgggt aagtactgga
    19981 ggaaagtgga cgattggcga atttttttct ttccttacaa attggaaaat tccttttgaa
    20041 gatatcaact attcgaataa ctctgaagtg gccctgttct atcacttttt tccaactgta
    20101 ttcctagcaa gtccatttgt gttatttggc aaaaaagata gcgaacaaaa gttactggga
    20161 cgtattttga tgattttttg tctgttttct atcttttgga ttaccgttgg gttgccaaaa
    20221 tggctagcag aaatcactct gctgtcttat gttcctccat taagagccat ccttactttt
    20281 agttttgcgg cttgtttatt atcgatctgg tttatcgctt atatttggag agaagatgtt
    20341 attcctattt ggtataaatt cattttgttg gcagtaaatg catggtctta tttctatgcg
    20401 attacgcatt cgaaaatgga taattatttt tcggattttg aaaccatcgc agttgctgtg
    20461 ttgggaacag tgattttagc ttttgcatta tttggctgga gacgcttgtt ttacctcgct
    20521 tttgccgcct tagttatcgt atctggcttt ttcgtcaatc cagtcgtaga aggtacagga
    20581 gcgatttttg aaaaaacact ggcaaaagaa atccaaaaaa tcgatcaaca agatcctggt
    20641 aaagtttggt tgtctgaaga tgaattatat aacttcaccc caacattggg agtgaaatcc
    20701 ttcaatacag tacgctttta tccagatata gctgcatgga agaaaatcga tccgaaagaa
    20761 gaatacgaga agtattataa tcggtatgct catacaagag cttttatcgc taaggaagat
    20821 acaaagttca ttttagatcg tccagatatg ttttcggtca cgttgaattt tgaagacgca
    20881 gaaaaattag ggatcgacta tgtgatcagt aaacgaccat taactgatta caaccaatta
    20941 tatgaagcgc agttcacgca gctatatgga ccggataaag acggttatat gatttttaaa
    21001 gtagaatatc cggattatcc agatgtacca caaacacaaa ctcaggaaaa tcagctagtc
    21061 gtacagtaat aggctagctg agaataatcc tgaaatgtta gtagaaagga gagtggagat
    21121 aattcaagca atcgtacaaa aatttgtcaa caaaatgagt gtcggtttct tgcttttgtt
    21181 actgacgcta gtcttttttg tttggacagc agggttaggt tttccagcaa ctttgtttat
    21241 atataacaat agttcattac ttatcgcttt tagtgtggct attttgctca ttttaaatgt
    21301 ttataaagca aaaggcgtcg attttcttta tctaggtgtt gcgcttgccc ttttcatttt
    21361 cttttcttac tttcgggaat taagaaatga gtctttattt ggagacttac tgtttccttt
    21421 gattatttta ttttgtttag taattaaatg gatcgagtgg acaaaatggg atcgcggtat
    21481 ttatctgatt gtcttttcgg tcttcctcgg aatcacgtta tatcgtgtat ttacagagat
    21541 ccaagtacca gaaggacaaa gcatctgggc tccaggcaat tcgctttctg atatttggat
    21601 caatacgaat ataatcggaa gttctttgat gactcttgct ttattgatca gtggatttgc
    21661 cagttctttt gaacgatggt atgtacgaat catcggtgca gtagcagttg ttgcagcttt
    21721 tctcgggatt tgggtctgcc aatctagagg tgcattagtc gcgttgattg tttttgcgat
    21781 attggatctt ttacctaaat cgttgatgcg tgtcattcgt gcgccattta ttgcttacac
    21841 ggttacgatt cttttagctt tgccgatttc ttatctggcg gctgtctctg aaaaagtcaa
    21901 tttgtttacc ggtcgagaag atatttggca taaattctat cagacgctag gagaaaaatc
    21961 tgaacaaatt ttactaggaa tgaaaacatt tatcttccaa cgaggaaacc aatttttagg
    22021 aaaccacaat agttataatt ctattttgaa tatctatgga ttgataggat ttgggattgc
    22081 tgctttgctg cttatccttt ttattggtcg cttaacgttg aaagcagatt tatccaacgg
    22141 gcagatgact tttatctggg ccttttttgc ggtgatgatg cagtcattta tggaggatac
    22201 attgacttca tacccatggg ttccgattat ttatatcctg ttggctatgg ccgttcatcg
    22261 atatgatgaa ccagaagttg cggaggaatt ctatgttatg gaagaggcat atgacgatat
    22321 gacttatgat gatacatctt atgaggaaca accagatagc gctcattctt ccaggatcca
    22381 acgctatcat tgataggcac aaaatacgag agaggctgtg acaaccgtcg cagccttttt
    22441 tggtttattg caattgtcta gcatcttctg taaaatagaa acgttagaga aaatcttgta
    22501 tcatagaaaa ttaagaaaga aataagaacg cagctcggta ccaaaaatat ggtaaaatgg
    22561 cacttgactg taattcactg aaaatcgctt ggaggaacac aaatgtttaa agatttgtat
    22621 ttatttatga aggacattta tcagaacaga aaattattgc tacagttttc gatcaatgac
    22681 ttcaaatcaa gatatgcagg atcgttttta ggaatcttat gggcgtttat caatccgcta
    22741 tttactgtat tgatttattg gctggtattt ggtgttggac tgaaagcaca aatgatcgat
    22801 gcaaaatacc catttatcgt atatttagtt accgggatga ttccctggtt cttcttctca
    22861 gatgcatttg catcaactac ggttgttttt cgggaatata cttatttagt aaagaaagtc
    22921 gtattcaata ttcgtatctt gcccacgacg aaaatcctat ccaatctgta cacccactta
    22981 ttcttcattc tgattggcat agctgtcgcg cttataaatg gtatatatcc ttcagcaatg
    23041 tctttacagc tgatttatta tttattttgc atgtgtgctt tcttgacagg attgacttgg
    23101 ctgacggcat cgatccaacc atttttacct gatatcatgc aattaattac gatcgtgctg
    23161 cagttgatca tgtggacatt accgatatta tggagcccta atcagtttga ttcaggtctt
    23221 gtaagcatat tgaaattaaa tccgctgtac tatgttgttc aaggttatcg tgagtcattt
    23281 ttaagtgaag cttggttctg ggagcatgga acatatactt tgtatttctg ggttttcacg
    23341 ttagtaatgt tcgtaatcgg ctctgcagtg ttccgtagat tgaaaccaca tttttcagat
    23401 gtgctgtaag gagaatagct atgacagaat atgcaattag actaaaagat atcacaaaat
    23461 cttataatat gtacgcaaaa ccttcggatc gatttcgtga agccctcaat ccttttaaga
    23521 aatcctatca tgatgtattt tatgcgttga aaaacgtgaa tgtagaaata aaaaaaggtg
    23581 agatgatcgg tttcgtggga gaaaacggat cgggaaaatc tacaatgttg aaaatcatta
    23641 cgggagtact gacaccaaca tccggcacga tggaaatcga aggaaaaatc tcagctttgc
    23701 tagaactagg atcaggagtc aatcctgagt attctggcta tgaaaatatc tatttaaatg
    23761 gaatggttct aggattttca agagaagaag tcgatgaaat ggtcgatgat atcattgaat
    23821 ttgctgacat cggagaccat atttatcaac ctgtaaaaac ttattcaagc gggatgttcg
    23881 ttcgtctagc ttttgctgta gcaatcaatg tgaatcccga tattttgatt gtggatgaag
    23941 cattggcagt aggcgatctt gaatttcaac taaaatgtat ggaaaaattt acagaaatca
    24001 agaactcggg aaagacgatt ttattcgttt ctcatgatat cagttcgatt cgtcgttttt
    24061 gtgatcgttc ctattggttg aaaaacggag aagtcgtcga atatggcgat acgatggaag
    24121 taacgacgaa ttatgaaaac tttttaaaga aaaaatcagt taaaacagtg gatcggaata
    24181 aaaaccaagt agaacggttc gccgctccag atatcgtcga cgtgacgaaa gcggaattgt
    24241 tggataaaga caaaaatccg gtggatatgc tggaacaagg agaaaaacta tacgttaaag
    24301 taacttatga agtaaaagat gatacaatca aaaatccggt tttaggaatt gcgctacgaa
    24361 cagtcgacaa tttttatgta tgcggactta atactctact agatggtatc aagattcctt
    24421 ggaaaaaagg agagaatatc ttttatctgg agtatgaaaa gttaggtttg ttagctggtg
    24481 aatattattt tgacgttgcg gtctttgaag aaaatgcaac ggttcctttg gtatataaga
    24541 caaagtacat gaacttgttt gtcagcggtt cttatatcgg agaaggcatc gtggtcttag
    24601 accataaatg ggaagaaggg actcatagca atgaaatatg attttgaaat ggacctagat
    24661 gaacaaagca gtgtgggaaa aattgccgca cagatcaaac caggaagtaa agttttagag
    24721 tttggtcccg gaaacggccg attaacgaaa catttaatcg gagcaaaaca atgtgaagtg
    24781 agcattgttg agttagataa ggaattgttc gattttgtca gcgaatttgc tcaagatgga
    24841 ttttatggtg atatcgaaag ttttgagtgg gcaaactatt atgctggaca gacatttgat
    24901 tacgtcttgt ttgcggatgt tttagaacat ttggtagatc ctggaaaaac attgaagaaa
    24961 gtcagagaat ttttgaatga agaaggagag atcctgatta cattccctaa cttggcgcat
    25021 aattctgtca tgatcgattt gttcaataac caattgccgt gggcttctta tggtctccta
    25081 gatgaaaccc ataattcttt ttatactcat gatggcttcc aaaaagtttt tgaaaaagcg
    25141 ggattattca ttaatattga agattatttg tacttagctg taggtgatac agaattaaaa
    25201 tcaacttatg aagaattgcc ggaagctgta cgctatgatt tcaaaatgcg accatttggt
    25261 gaagtctacc aatacttttt ctcattgatg aaacatccag tagcacaaag ttccattgca
    25321 gagccacaaa attctaatta tgtaaaagtg ttagaagtaa cccagcaaac gaaacaagat
    25381 gaaacaatcc aacaaatacc attcaataat ttcacagggg aaaatgagac actaagtttc
    25441 cccgtatcag aaacaacaga aagaatggtg tttcgcttcg cgcaacaacc tagctttatc
    25501 gaattcagcg cagaagctgc cggagaaaaa ctaacattta tcgattcgaa tgctgtagtc
    25561 aaaacagtaa atgattgtta tttgtttgat gggaaagaat taccagagtt cgttctaacg
    25621 gatatttctg ggaaagaagt gactatccat tgtcactatc gctttatcgg ggaattgaca
    25681 ccaacaatga aagaattgtt ggaaacgatt cgtcccatgg ctgaagtcac aaagcagctt
    25741 tctgagaaaa atgacgaatt agaaagagaa aatcatcatc ttcttgagga aaatacaaga
    25801 ctagaccata cgttaaaaac aaccacaaat cgctattgca cattgttgga aagtgatgaa
    25861 tggacaataa aacatagact aggacgacgt aagaaagaaa cttcgaaaaa aatccaagaa
    25921 aaagaacttt ctatatgtat tgacgagaaa atctgggatg cagaaacaaa aatattaaaa
    25981 atcatcggat ggggaatcgc taattcggat cgccagccct tgtcctataa gttatcagct
    26041 gaccaatcgc catttttcga agcaattcct gtttcacgag aagaagtcaa tcaagcagaa
    26101 cagctcgcaa aaggaacaga agcgggattt gagttacgaa tcctttgcga gcaagaacgt
    26161 tcattcttag tggaagcagt agctcaaaat ggccaatcat ggatcattga aatgtaaata
    26221 atgattaact tataaagata aggagtaaac gaatcgtgca aaaaaaagaa attgccgtat
    26281 ttatcgatca aatcactcgt gaacgggcca ctggcgattt gcttattgtg ggctgggcaa
    26341 ttgatgaagt gaccaaagaa atccctacga taaaggtaga aaaagaaaat gtgattgctg
    26401 aagcaacaca tgtcgtaaga ttggatatca atcatttata taatcttgat gttaagaccc
    26461 aaagcggttt taaggtacgt ttatcaggga aaatgagagg aaaagccatc ttagacttcc
    26521 aaacagcgag acatcaaaat ggcatagctg tgaaattaaa cggtaaatac ccttatgatg
    26581 acggcattga atcttcatgg gaaagaaaaa aaagattact gaaaaaaggg ataaattatg
    26641 caaggactca tggcgtaaaa aaagcgatcc gtcgggtcaa attggaattg aagccaggat
    26701 cgatcgacta tgcagagtgg atcagtcgtc atgagaaacc agatttgaaa gagcaaagga
    26761 aagaagcaca aggatttgcg taccgtccat tgatttccat acttatgcct gtctataacg
    26821 ttgaaatcaa atggctcgaa aaatgcattg attcggtact ggatcaaacg tatgatcatt
    26881 gggaactatg tatcagtgat gatgcttcta ctgatccagc tatccgaaag tgtctggaat
    26941 cctatcaagc aaaagatgat agaatcaaag tcgttttccg aaaagaaaat ggacacatca
    27001 gtctggcaac taattctgca ttggaaatag cagaaggaga atttatagca ctcttagata
    27061 atgatgatga attaccgcca tttgcattat atgaagtggc aaaagtgcta aacgtacatc
    27121 cagaactgga tgtgatctac agtgacgaag ataaaatcga tgcagatggc aatcgctttg
    27181 atccgcattt caaagcagac tggtcgcctg atacattgat gggaaataat tatatctctc
    27241 acttaggcgt atatcgaaca agcattgtta aagaacttgg cggtttccgt aaaggctatg
    27301 aaggttctca agattatgat ttggtccttc gtgtgacaga acaaatccct gcagatcata
    27361 tttaccacat tgaccgagtc ttgtatcatt ggcggacgat cccaggatca actgcaagta
    27421 atggcgaagc caaaagttat atctatgatt ccggagtgaa agcattgaca gatgccctgt
    27481 ctagaagaaa catcaaagga agcgtacgtc ctggcagaat ttctggattt tatgagattg
    27541 cttatgacgt cttgcaagag gatttggtca gtgtgatcat tccaacgaag aatggctatg
    27601 aagatctaaa aacttgtgtg gattcgatca tcgaaaaaac gtcttattca aattatgaaa
    27661 tcattattgc ggataacgga agtacagatc caaaaatgca agaattattt gcagaataca
    27721 agcatcagct gaaagaccgc tttatcgtag aattgattga cattccattc aattattctc
    27781 gaattaacaa tttagcagca gaaaaagcaa acggcaaata ctttttattc ttgaataacg
    27841 atacagaagt gattgagcca gattggatga cggtgatggt ttcttatgca cagtttgatc
    27901 gaatcggctg tgtaggagca aaactgtttt atccagatga tacaacgcag catgcaggag
    27961 tattattagg aatcggtggt gttgcagggc atgcattgaa taactatgat cgaacacatt
    28021 gtggttattt cggccgattg gtcattgacg tcaattactt agcagtcact gcagcttgta
    28081 tgatggtcaa ggcagctgac ttcaatgctg ttaacgggtt tgatgaaaca ttagaagtag
    28141 cattcaacga tgttgacttg tgcttgaaag tttatgaact gggtcgttac aatgtctatg
    28201 cacatcaagc agaattgtac catttcgaat ctaaatcaag aggttatgaa gatactccag
    28261 aaaaacaaag acgttttgct ggtgaaatca aaaaaatgca agataaatgg ccagcatata
    28321 ttgcgcatga tccattttac aatgataatt taacaaaaga aggaatcggc gacttttcgt
    28381 tgagaccaga ttaaactata ataaaaagct gttatgttgt gattcgctcg cacataacgg
    28441 ctttttatag ttttttgtca aaaaaaggca gaaggtgccg actcaaaaaa ataagtcgag
    28501 gttgggacag aagtgtttaa ctccgagaaa taagaagaaa ttcacgaaaa ttgcttttca
    28561 aatttttgtg aatttcggct tatttaagaa gaagttgctt ctgctcccac cgtttattcg
    28621 tttttaaaga atgagacaaa agtgtttctt acttttgtcc cacgctctta ttcatgctca
    28681 gagcgccaat agatacaaaa tcatagccaa agtttcacga accctagctg tcaaagaatc
    28741 gatattttat tttaatatag gctattttaa aataaatggt ttaaggtatt cctctacaaa
    28801 agccactcta tcaattatca tgggtttaaa ataagaagtg atggagataa ccagattgtt
    28861 cttagcgtca atataaagaa catttccact attaccaatt gctgaatata tttcgttctc
    28921 agaatctaat acccaccata aatagccata tctcatattt tgtaagtctt ctaaagcact
    28981 ggttctaggt ttgaacatct cgtttatcca catgggtggt acgatttgtt ttcctttata
    29041 catcccttta tttaggcata atacaccaat ttttgccaga tcacttgccg ataaacacaa
    29101 accatatcct gccgtcccga tatttagtgg atcacaaaac cagacattgg ttttaggaga
    29161 cttatccatt gtaaactgct tatgttcttc agctgtttca gcataataat tgacatggtt
    29221 tggtatccct ataggatcaa atagatactt attggcaaaa tcaacagttg ttagcttact
    29281 tgtctgatac aacaagccag ttaatatgtg taaacagaca gtttgatagt tgaattcgcc
    29341 ggttatacct tttcttcctc ccaataaatc tagtgatgtt tttgtccaat cttcacttga
    29401 acagactttt gtccatggat cgcctttaca tttgtagggt gctttcattg ttagcaagtg
    29461 cttgattgta atagcgtaaa tagttttctc cccgcgtttc actttatact ctggaaaata
    29521 atctaatact ttatcatcga tacttttgat taatccttgc tctaaagcaa tgccaatcag
    29581 caaagataca atacttttcg ttgctgacat gatatgacaa gtatcgtctt ttttataacc
    29641 attccattca tctgtataaa cttctacccc atccttatat gcgacaattt gacatatatt
    29701 tggttgtcga aaaccaataa aatcatgcaa ctcttgttta ttcataagat attacctcac
    29761 tttcttctat aagcataatg tcattaaaaa tcgatttcaa ttttttcgat tcttcacgta
    29821 atacaggtat tcttatggac tagacagcgc tttgggaaga tggattctct gaaaaatata
    29881 aaggttcact ttatgagtgg ataaaaaaag cagcaaatac ttcgacttct ttaatttacc
    29941 aacattagtg aaaatcgatt catctggaga tttgtaattt agagtccttg tcttgattag
    30001 aggtgtataa agctttttat tagacatttt taaattccat tacaatttgc ttataaacta
    30061 ggtttttaaa ggtgactatg gtaagataat agagatatta ttttgtgatt aggagtgtat
    30121 atatgaataa aaatggagaa tggagtgctg cacgacggat attcattata ttaatggatg
    30181 ttattgtata caatgcagca atatatagta gtttcttact gaagtttcgt ggagagatcc
    30241 cattacgaaa tttagaaact ttccaacact cagcaattat tatttcagtg atttttattg
    30301 cgttgaacat tttgttgggt gcatatgttt tttataatcg aatgatcagt gacatcgtgt
    30361 ttgtcacagt catcggtcag gtattgatga cactagggat catggtagtg acttttgcgg
    30421 gccgctggtt tgcttttcca cgtcttgtta tcttactttc atttgttctc ggtacgcttt
    30481 tcttaagtat ctatcgtatt ctcgtatata aactttattt acgcgtaagt cgagataaaa
    30541 aggtcgtcat tattgggtta gaaaaggatg tcgcaccagc aatccaaaat tttggttcaa
    30601 agaaaaacaa caaacataaa gtcgaagcag tcattcttga taactattat gcaaacatca
    30661 aaaatatgat taaagacatc gatattgtct atcttgcttc tcatatcgaa gaaactgaaa
    30721 aaatcaaaat ctatcaatta gttactaaaa atgaaaaaaa attgtttttg aatacaacat
    30781 ttgaaaactt gacattgatc aatccaaata ttatgaattt cgaagatgaa agtattattg
    30841 aagcatctgg atttagaatc caacctgaat atgaactatt caaacgtttg tttgatatca
    30901 tcgtttcact tgttttatta gttattgctt caccatttat gttattcaca gcaattttag
    30961 tcaaagtgac atcaccggga ccaatcatct ataaacaagt gcggatcaca aaaaatcaaa
    31021 aggaattttc aatctataaa ttccgctcga tgaccgccac agccgaagca aaatctggac
    31081 cagttttagc taagagcaat gatgcacgag taacgcctgt aggtaaattt attcgagctg
    31141 tccgctttga tgaattacca caaatcttca atgtgctgaa aggcgatatg tcgatcgtag
    31201 gaccacgtcc tgaacgtcct ttcttcgtcg atcagttcaa tgcagaaaac ccttattact
    31261 acttacggca taatgttcgt gctggtatca ctgggtatgc acaagtctat ggaaaatatg
    31321 tctctgatta caacagtaaa ttacgttttg atttacttta tatcaaaaaa tattcattga
    31381 tgcttgattt aaagatcttg ctgcaaacca tcaagatcct atttgataaa atgtcctctc
    31441 aaggacttga agaagacgaa aatgtgatct cattggcaga aattgctttt ccgaatgaaa
    31501 aaatctttcg ctagttggga ggcgtaaaaa tgaacaatcc gaaattcagc ataatcgtac
    31561 cagtatacaa tgcagaagca actattggtc gaacgattga tattctaaaa gaattggatt
    31621 atgaagagta cgaagtcgtt ttagtaaatg atggatcaac agatcaaaca caggaaatca
    31681 ttcaagaact gattgaaaat gatgaacgtt ttgaattgat tactacgacc aatcaagggc
    31741 ccggattagc aagaaacgaa ggaataagac agtcaaaagg agaatatctc ttattcttcg
    31801 atgcagatga cacgccagta aaaacgatct tgtcagatta tgatcatttg ctagaaaaga
    31861 gtccaaaagc ggatcttgtt gttagttcgt ttgtttttcg tacaatggac gagggaagaa
    31921 tcgtttccga aaaagaaaac ttagttacag aatgtcacta tctaactcac gaagagttta
    31981 taaaagacat gtatcagtta atgaatgaac agttgatgta tgttgtatgg aacaaatgct
    32041 atcgtagcga tattctgaaa aataaccaaa ttctatttaa aacttataat agttgtgagg
    32101 atcgaatatt taacttacat tattatgaat actgtcatca agtgatcatg aacccaaaag
    32161 tagaatatat ttatgaattt gaaggtggga aggggatcac taatcaatac cgacctaaca
    32221 agttcgaaac atttaaagaa ttctattcat tagcaaatac tgtaacagac gatattaata
    32281 aagacggtat ggcggcgctt cttttaaaag ggacaacttc agttattttt tctatttata
    32341 gtacctctgc aagaacttca aaagagaaga aagacgaagc aaagcagata ttgagtgatc
    32401 cagtgatccg agaagccaag caaattgcta agacggattc ttcagcaaaa aaaataacaa
    32461 agttgcttta caatatgcca gctccactat ttttatctgc tgtaaaagtt ggaagcttcg
    32521 ttgaagtgaa aatgccaggg ttaatggctg ctttgaagcg agtatattag ttaatggagg
    32581 aaaatataat gaaaagaatt ttgcattttc agggacgaat gggtttaggt ggagcagagt
    32641 ctttcatgat gaatttatat cgtaaaattg atcgtacaaa ctatcaattt gattttttga
    32701 tttatgaaga ttatgcagat gttcaagact atcattcaga gattgaaaga ttaggaggcc
    32761 gtatttttgt tgtacctaat cctaagaaaa atatttttaa atatttaata gaagtgaata
    32821 agttactaaa aaaagaatct ttttctatag ttcacaatca ggtttatttt ggcgggggaa
    32881 ttaatttatg gttagccaaa aagaatggaa tcagacagag aattgctcat agccatgcaa
    32941 ctgaagatgg aaaatctcaa aatattgtaa tgaatgtatt gcgtaaattt ttaaccaaat
    33001 tgttgttaca aaatgcaaca gactaccttg ccgttagtca agaagctggt gaaagtctgt
    33061 ttcaaaacca cccctttgag atagttcata atggtattga tttagagctt tatagtaaaa
    33121 attcagaagc taaggttaat aagagaaaag aattggatat ctcaatgagt acttttgttg
    33181 tgggaaacat tggacgatta gagaaacaaa aaaatcaatc ttatttgtta gagatttttt
    33241 tagaaatact aaaaatgaat tctgattctt acttgatttt agtaggtgaa gggtcactta
    33301 gaaataaact gaaagccaaa gcagtagaat tggatataga gaaaagagta aaatttttag
    33361 gagaaagaaa cgatattccc gagttattat ctgtgatgga tgtttttgta atgccttctc
    33421 tttatgaagg tctgccaatg gttggattag aagcacaagc agcaaaatta aaattagtct
    33481 tagcagatac tatttccaaa gatacaaagt taacaaataa tgtggatttt gtatcattag
    33541 atgaaacacc acaagaatgg gcaaaaaaag taataaaaga gccgtatgct aataaaataa
    33601 cacaagaact aaagagttat gatgtttcgt acactactga acaaatggag agtatatata
    33661 gtagagatca ttaaaaatgt tcaagatatt ttaggagtga ttatttttga aaatatgtta
    33721 tttgatattg gcatacaatg atattggcaa cttaaagaga ttggtcaatc gattgaacga
    33781 aaatgcagtt tttattattc atatagataa aaaaactgat atagaaccat ttattgaagc
    33841 atttaaatca tatgataatg ttgaattttt atgtaataaa aaccgtgtta aaatttattg
    33901 gggtggtttt tccattgtac aagcagaaat caatttagta aagagagcat tacaaaatga
    33961 gaaatattta aaatatgtat tattatctgg tgctgattat cca
//
LOCUS       DAFLWQ010000029        33263 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.030, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000029 DAFLWQ010000000
VERSION     DAFLWQ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.030"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(41..229)
                     /locus_tag="L1V16_001299"
     CDS             complement(41..229)
                     /locus_tag="L1V16_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBN1275648.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            499..861
                     /locus_tag="L1V16_001300"
     CDS             499..861
                     /locus_tag="L1V16_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBN1275649.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            913..2595
                     /locus_tag="L1V16_001301"
     CDS             913..2595
                     /locus_tag="L1V16_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBN1275650.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2712..4748
                     /gene="recG"
                     /locus_tag="L1V16_001302"
     CDS             2712..4748
                     /gene="recG"
                     /locus_tag="L1V16_001302"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBN1275651.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4797..5798
                     /gene="plsX"
                     /locus_tag="L1V16_001303"
     CDS             4797..5798
                     /gene="plsX"
                     /locus_tag="L1V16_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBN1275652.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5920..6162
                     /gene="acpP"
                     /locus_tag="L1V16_001304"
     CDS             5920..6162
                     /gene="acpP"
                     /locus_tag="L1V16_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBN1275653.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            6430..7434
                     /locus_tag="L1V16_001305"
     CDS             6430..7434
                     /locus_tag="L1V16_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1275654.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            7435..8379
                     /locus_tag="L1V16_001306"
     CDS             7435..8379
                     /locus_tag="L1V16_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1275655.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            8379..9341
                     /locus_tag="L1V16_001307"
     CDS             8379..9341
                     /locus_tag="L1V16_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1275656.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            9368..10282
                     /locus_tag="L1V16_001308"
     CDS             9368..10282
                     /locus_tag="L1V16_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1275657.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            10308..12089
                     /locus_tag="L1V16_001309"
     CDS             10308..12089
                     /locus_tag="L1V16_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1275658.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            12437..13123
                     /locus_tag="L1V16_001310"
     CDS             12437..13123
                     /locus_tag="L1V16_001310"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBN1275659.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            13143..16724
                     /gene="smc"
                     /locus_tag="L1V16_001311"
     CDS             13143..16724
                     /gene="smc"
                     /locus_tag="L1V16_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBN1275660.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            16733..17542
                     /locus_tag="L1V16_001312"
     CDS             16733..17542
                     /locus_tag="L1V16_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1275661.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            17553..18551
                     /gene="ftsY"
                     /locus_tag="L1V16_001313"
     CDS             17553..18551
                     /gene="ftsY"
                     /locus_tag="L1V16_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBN1275662.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            18738..21005
                     /gene="gshAB"
                     /locus_tag="L1V16_001314"
     CDS             18738..21005
                     /gene="gshAB"
                     /locus_tag="L1V16_001314"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HBN1275663.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(21094..21546)
                     /locus_tag="L1V16_001315"
     CDS             complement(21094..21546)
                     /locus_tag="L1V16_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HBN1275664.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            21696..22646
                     /locus_tag="L1V16_001316"
     CDS             21696..22646
                     /locus_tag="L1V16_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBN1275665.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            22639..23598
                     /locus_tag="L1V16_001317"
     CDS             22639..23598
                     /locus_tag="L1V16_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBN1275666.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            23595..24350
                     /locus_tag="L1V16_001318"
     CDS             23595..24350
                     /locus_tag="L1V16_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1275667.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            24373..25326
                     /locus_tag="L1V16_001319"
     CDS             24373..25326
                     /locus_tag="L1V16_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1275668.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(25970..26266)
                     /locus_tag="L1V16_001320"
     CDS             complement(25970..26266)
                     /locus_tag="L1V16_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HBN1275669.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            26621..26977
                     /locus_tag="L1V16_001321"
     CDS             26621..26977
                     /locus_tag="L1V16_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBN1275670.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            26987..27886
                     /locus_tag="L1V16_001322"
     CDS             26987..27886
                     /locus_tag="L1V16_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HBN1275671.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            28403..29134
                     /locus_tag="L1V16_001323"
     CDS             28403..29134
                     /locus_tag="L1V16_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBN1275672.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            29279..31306
                     /locus_tag="L1V16_001324"
     CDS             29279..31306
                     /locus_tag="L1V16_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBN1275673.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            31414..32511
                     /locus_tag="L1V16_001325"
     CDS             31414..32511
                     /locus_tag="L1V16_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBN1275674.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            32818..>33263
                     /locus_tag="L1V16_001326"
     CDS             32818..>33263
                     /locus_tag="L1V16_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1275675.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT        11138 a         5762 c         7123 g         9240 t
ORIGIN      
        1 aaaaaccgtt cactatctga acggtccaag tatcattcaa ttaaacgcgt tcaacttttc
       61 ctgatttcaa agcacgagtt gacacccaaa cttttttagg ttttccgtcg accataacgc
      121 gaactttttg taagttaggt ttaacagtac gttttgttga gttcatagcg tgtgaacggt
      181 tgtttccact ttttgtcttg cgacctgtaa agtaacaaac ttttgccatg gtaatttcct
      241 cctttgcctt gatttggagc aatagaataa ttcagctcat accagactaa catatcatat
      301 agaatggaaa tttgcaagta cattttcata gatacaattg acaattgaga agaataattg
      361 taaattaaac aaggttatac ctgaaatttt gcaaggtttt tgagtacttt gggtaactgc
      421 cttttatttc aagttgcgct atgataaaat atgatagaag aaaaatggga gttttttacc
      481 cgttaaggag gctcattcat ggctgtaaaa attcaaacgt cagctggaac cattgaaatt
      541 accaatgatg taattgcaac agttgttggt ggcgccgcga cagatgtgtt cggtgttgta
      601 ggaatggcca gcaaaaatca aattaaagat aatattactg agattttgcg taaagaaaat
      661 tactcaagag gagtagttgt ccgccaagaa gataatggta ttgctgtaga tgtttatacg
      721 attatcagct atggtacgaa aatctctgaa gtttcccgca acgtccaaga aaaagtgaaa
      781 tacaatctag aggcattatt aggcgtaact gccaattcag ttaatgtctt tgtacaaggt
      841 gttcgtgtac tgccagacta ggcaggagac tggctggtaa ctcagcagtc gatctgaagg
      901 aggattatct aggtgagtgt aacagaaata agtgcaagcc agttccagga aatggtccag
      961 gcaggtgcga atcgtctgca agtaaatgca gaatacgtca attcattaaa tgtattccct
     1021 gtgccagatg gcgatacggg aacaaatatg aatctatcta tgactagtgg agctaaggca
     1081 gtagtagatt caacctcaga aaaagtagga gaattagcag caatgctttc aaaaggattg
     1141 ctgatgggtg cgcgcggaaa ttccggcgtt attttgtctc aattgtttcg tggattttct
     1201 aagcaaattc cagatgttgt ctcattaaat gcttccgatc ttgctgcagc cttcactcat
     1261 ggagttgaaa ctgcgtataa agcagtaatg aaaccagtag aaggaacgat tttgacagta
     1321 gctagagaag cagcgaaagc tggagaaaag aaagcaaaaa gtactgatga tgtcgttgaa
     1381 gtaatgacag ctgttgtaaa aggggcaaag cgtgctttag ctaaaactcc agacttgctt
     1441 ccagtcctaa aagaagtcgg tgtcgtagac agtggagggc aaggactgct gtttgtttat
     1501 gagggctttt taagtgcatt gaatggagaa ttccaagcgg atgaaacata tgaaccttct
     1561 ccagcagaaa tggatgatat ggtcaatgca gaacatcatc gcagtgtcca aggtcaaatg
     1621 gcgacagaag atatccattt tggttactgt acagaaatca tggtaaaaat cggagaagga
     1681 cctacagtcg atagtacatt cgattacgaa gaattccgta actatttaga tggtatagga
     1741 gattctttac ttgtggtcaa tgatgacgag atcatcaaag tccacgtgca tacagaaaac
     1801 ccaggagaag tcttgaatta tggacaaaaa ttcggttcat tagtcaaaat caaagtcgac
     1861 aacatgcgct tgcagcatga gacgattttg gaacacgatg aagaagtgaa cgagtttgcg
     1921 aaaaaagaaa caccacgtat cccgtatggt atcgtagcga tcgctgctgg taaaggcgtc
     1981 caagagctgt ttgaaagttt aggcgctaat tatgttatca gtggtgggca aacaatgaat
     2041 ccaagtacgg aagacattgt taaagcgatt caagaagtaa acgcagataa agtgattgtc
     2101 ttgccaaaca ataagaacat cttcatggca gctgatcaag cagcagaagt agcagatatc
     2161 ccagtagcag ttgttccttc aagaacgatt tcccaaggat tgacagctat gctttcattc
     2221 aatgatcaag cttctttaga agaaaacaaa gaaacgatga cagaaatgtt gtctagcgtt
     2281 gtgagcggtc aagtcactca cgcgatcaga gatacctcaa ttgacggtgt agagatcaaa
     2341 gaaggagact ttttgggcat gatcgatgga aaaatcctga tctctaaccc agatatcaca
     2401 gcaacagcgt taagtacact agaacaaatg atcaatgagg acacagagat cgtaacgatc
     2461 ttggcaggtg atgaaggaac agttgaacaa gcaaatgaat ttgctgagaa actaacagaa
     2521 aaacatcctg atttggaaat cgagatccac caaggagatc agcctgtcta tccttatcta
     2581 ttttctgctg aataatttct gtgtcagaat atctttctaa cacagtattc attcataaaa
     2641 ggccttcggt tagtgatcag gtatgatcgc tgaccaagtc ctttttttgt taagggaggg
     2701 aggaaaaatt tatgcgttct ttagatgatc caatcactat gctggcagga gtcggagaaa
     2761 aaagagcagc tagtcttgcc agcttgggca tccaaacgat tgaagactta ctgacttatt
     2821 atcctttccg ctacgaagat attcaggaaa gaaatctaaa cgagatccaa gatcaagaaa
     2881 aggttacttt gaaaggaatc gtagtctcgc ctcctgtgat gaatcgattt ggttataaaa
     2941 aaagccgatt gcaatttcgt atgatgcaag aacatgatgt gttcaacgtt tcttttttta
     3001 atcaacctta tctaaaagaa aaagtcattt tatcggagga aatcgccgta tacggtaaat
     3061 gggatgcaaa gcgtaaagca ttgaacggga tgaagatttt aggttctcaa acaatggatg
     3121 acttttcgcc gatatatcac gtcaacaaat caattcgtca aacgacatta gttgatctaa
     3181 tcaaaaaagg gtttcaagaa tacggcacat tgattgaaga aaatctgcca aacaaccttg
     3241 tggagaaata tcgactgctt gaccgagctt ctgctgtaag aagtatgcat tttccaaaag
     3301 accacgaaga aaaccatcaa gccaaacgac gtgtcgtttt tgaagagttc tttttatttc
     3361 aaatgcgtct tcaaggattg aaaaaagcag aaaaagcaga aacgaatggt ttggagatcc
     3421 tttatgatgt ccaaaaattg aaagaattta ctcaaaagct accttttgaa ctgacaaatg
     3481 cacaaaaacg tgtaacgaat gaaatctgtc gggatcttcg cagtccgcag catatgcagc
     3541 gacttttgca gggagatgta ggtagcggaa aaacagtggt tgccgcgatt gcgttatacg
     3601 ctaccgttac agcaggtttc caaggtgcgt tgatggtgcc tacagaaatc ttggcacaac
     3661 aacatatgga aagcttgcaa cagctgtttg atcccaatga agtaaccatc gcattgctta
     3721 cggggtcaac gaaagcaaaa gaacgtcgtg agctccttga aaaactagag caaggggaaa
     3781 ttaacatcgt gatcggcaca catgcattga tccaagatgg agtcgaattt cagaatttag
     3841 gtctagttat tacggatgag cagcaccgtt ttggcgtgaa ccagcggaaa gtacttcgtg
     3901 aaaaaggctg gcgaccagat gtcttattta tgacagcgac tccgattcct agaacattag
     3961 ctattacagc atatggtgag atggatgtat ctatcattga tgaacttcca gctggacgta
     4021 tcccgatcga aacacgctgg gtaagaacac ctcaattgga cagtgtactg gattggacga
     4081 aaaaagaact ggcaagagga catcaaatgt atgtcatctg tccgctgatt gaagaatcag
     4141 aagcattaga tgtaaaaaat gcagtggaaa tctatgaaaa acttcgtgaa ctatttgcac
     4201 caaaatatga agttggcttg ttacatggta aaatgaagaa tcaggaaaaa gaagtaatca
     4261 tggaagcctt caaagacaac cagatgcaga tattagtttc gactactgta attgaagtag
     4321 gggtaaacgt gccgaacgcg accgtcatgc tgatcatgga tgcggatcga tttggattgg
     4381 cacagctgca tcaacttcgt ggacgtgttg gacgcggaag tgatgcttcc tactgtatct
     4441 tagttgctaa tcctaaaaat gaactaggtg tggaacggat gaaaatcatg acagagacca
     4501 ccaatggttt tgtactaagc gaaaaagatc tggaattacg tggtcctggt gaagtatttg
     4561 gcttccgtca atctggtctg cctcaatttg cgattgctga cttggtgacg gatggaaatg
     4621 ttttggaggt agccagagaa gaggctgcag ccctttggca gataaaggat tggcagatgc
     4681 ttcctgagta tcagccttta gcgcaaagcc tccaaataga aaatcaggat aatcgttatt
     4741 tcgattagca gactgtgcta tactttatac tgatgacgga aaaaggagtg gaaacaatga
     4801 aaattgccgt agatgcaatg ggcggagatc acgcacctca agcaattgta gaaggcgtgg
     4861 ctttagcgca gcaagatttt ccagaagtag aattcttact ttacggaaaa gaagcagaaa
     4921 tcaagaaata cttaacaaat gaaaaaaaca tcacgattat ccatacagac gaaaaaatca
     4981 atagtgatga tgagccagta aaagcaattc gacgaaaaaa gactgcatca atggtccttg
     5041 ctgcacaagc agtgaaaaac ggtgaagcag atgctgtatt ttcagcaggg aatacaggcg
     5101 cgctactagc agcagggttg ttcatcgtag gacgtatcaa aaatatcgaa cgccctggct
     5161 tgatgtctac cttgccagta gtagggaaag aaggtgccgg tttcgatatg ctggatcttg
     5221 gcgctaacgc agaaaacaaa ccagaacatt tgttgcaata cggtatttta ggttcttttt
     5281 atgcacgtaa agtccgaggt atcggacgtc ctcgtgtcgc actcttaaac aacggaacag
     5341 aagcaacaaa aggtagtgaa gtgacgaaaa aagcctatga actccttcag aatgaaacaa
     5401 gcttgaattt tattggaaac gtagaagctc gtgagctact caatggtgtg gctgatgtag
     5461 tggtcacaga tggatttaca ggcaacgctg ttttgaaatc tattgaagga acagcaatga
     5521 atatgatgaa tctattaaaa tctgctattc taaatgaagg gatcaaagga aaaatgggcg
     5581 ctatgctttt aaaagacggc ttacgttctt tgaaagcaga aatggattat tccaaacatg
     5641 gcggtgccgt tttgtttggc ttgaaagcac cagtcattaa aactcatgga gcaacaggcc
     5701 ccgatgctgt tcgctatacg atccgccaaa tccacacaat gcttgagaca gatgtagttg
     5761 gacaattagt cgaacaattt gaaaaaagcg aagaatagta tttggatatc tgaagcaatc
     5821 cgttccattg aaaaaaaggt ggacattcct gaaaaatgcc agtaaaatta gccatggtgt
     5881 aggtaattga caagtgtatg attcttggag gtgaaaaagt tgactcgcga agaagtattt
     5941 aacaaagtag cgaaaattat ttcaaatcat tttgagatag ataccgataa agtgacggat
     6001 gaattgaaca tcaaagatga tttaaaagct gattcaatta gtattatgga attcgtttta
     6061 gagcttgaag atgaattcgg tacggaaatt tcagatgaag acgctgaaca aattgaaaca
     6121 gtcggtggcg cagtagatta tatcagcagc catcttaaat aatttcaaat aaaagcaaag
     6181 aaggataaaa agctgcatac agctttttat ccttcttttt ttaatctttt tgacacgtaa
     6241 aagtcatttt tctgataatt ctggcgataa acagaaatta tgttgcaaag taaagcgatt
     6301 ttctatataa ttattaataa ttcattacac aaagataaga ataacctttg ttataaaacg
     6361 ctttattctg tgtaatgtcc ttttttatta agaaaaactt ccatttagga agcagagagg
     6421 ggtattcgat tgtccgataa ccaattatta gaagttcaga acctacatac aggattccga
     6481 ctcaaagatg actattacga tgcagtagat gacgtttcat ttactttaga caaaaacgag
     6541 attttagcaa tcgttgggga atctgggtgc gggaaaagta ccttggctac tacgattatg
     6601 ggattacttg atcctaataa cacaaaaatt acaggtgaga ttttatataa cgatctgaat
     6661 ttaatcgacc tgaacgaaac gctctataat aaaatccgcg gaaatgatat cggaatgatt
     6721 ttccaagatc cgttgtctgc attaaatcct ctcatgagaa tcgaagacca gatcaaagaa
     6781 ggactttcct atcacacaaa gatgaatgca gaacagcgtc aagctcgtgc actagaattg
     6841 ctagaacaag tagggattcc taatcctgcg agagttggac gccaatatcc ccatgaacta
     6901 tcaggcggta tgagacaacg tgtcatcatc gcaatcgcaa tcgcctgcaa acctccaatc
     6961 gtcattgcag atgaaccgac gacagcccta gatgtaacca tccaagcaca gattcttgat
     7021 ttactgaaag accttcagga agaaacaaaa acagggatca tcttgatcac tcatgactta
     7081 ggagtcgtag cagaaatggc tgatcgagtg gcagtgatgt atggcggaca gttcgttgaa
     7141 gtagcaggtg taaaagaact gtttgatcat cctaagcatc cttatacacg ctctttactg
     7201 aactctatac cacaagaagg aaatcatgat gcagaactcc atgtgatcga aggtgtcgtt
     7261 ccttctctga aaaacatgcc tcgtaaaggt tgtcggtttg caccacgtat tccatggata
     7321 ccagcaagcg atcatgaaga agagcctatc cttcatgaag tcgcaccgaa ccacttggta
     7381 cgttgctcct gctataagca tttccacttt agagacgaaa aaggagaggt gtagatgaca
     7441 gaattaatca caatcaaaga cctgaaagtt cattacccta ttcgcagtgg attcttcaat
     7501 cgagtaacgg atcatgtata tgctgtagat ggtgtggatt ttattatcga aaaaggaaag
     7561 acatatggtt tagtgggaga gtctggctct ggaaaatcta ctacgggaaa agccgttgtg
     7621 ggattagaaa aggtaacagc cggacaaatc atgtatgaag gaaaagatgt aacgaagcga
     7681 agcaaccgca aaaaaatggg ttataacaag gatgtgcaga tgatcttcca agattcaatg
     7741 tccagtttga atcctaaaaa gcgagtgttg gatatcattg ctgaacccat ccgaaatttt
     7801 gaacggttaa gcgatcaaga agaaaagaaa aaggtaaaag gactgctaga tatcgttggg
     7861 atgccggaag atgcgctata taaatatcct catgaatttt caggcggaca acgtcaacgt
     7921 ctaggagtag cccgtgctgt tgctaccaat ccaaaactga tcgtagccga tgaacctgta
     7981 tctgctctgg atctatctgt tcaagcgcaa gtattgaatt tcatgaaacg aatccagcaa
     8041 gaatacggcc tcagctattt attcatttca catgatttag gtgtagtaaa acacatgtgc
     8101 gacaatatcg caattatgta caaaggtcga tttgtagaaa tcggtacaag agaagacatt
     8161 tataatgacc cgcgacatat ctatacgaaa cgtctgcttt cagctattcc gcaaatcgat
     8221 gtagaaaata gggaaagcca caaagaaaat cgacgaagag tagaacaaga gtatatccaa
     8281 aaccaaaaag aatactatga tgcgactggt cgagtctacg atttgcgtac gatcacaact
     8341 acacacaaag tggcgttgaa agatggaggt gcaagctaat gtggaaaacg attctgcgac
     8401 gtgttttatt gatgatcccg caagttatta ttttaagtgt tctgatcttc ttattagccc
     8461 aagcgatgcc gggggatcca tttaccggtt tgatcaatcc aaatcaggat ccggcagtga
     8521 tcgaacagat gcgacaagca gctggcttga atgacccatg gtatgtccag tacttccgtt
     8581 ggatcggaaa tgctttgcaa ggcgattttg gtcaaagttt cttatacaaa cgctctgttg
     8641 ctgacttgat cggcgaacgg atcatcaaca ctttatatct atcgatcttg acagttgtcc
     8701 ttacttattt gattgctgtg cctctgggga tgcttgctgg ccggtatcaa aattcaatct
     8761 tggataagat tgtcgtaatc tacaacttct ttagttttgc tgttccttta tttatcttcg
     8821 gcttgatcat gctatttgtt tttggttatc gtttaggctg gttcccaaca agtggatcac
     8881 aaacactagg tttgcaaggt ggatttatca ctcaatggat agaccgtttg aaatatattc
     8941 tgttaccatc aattacccaa gcatttttgg cgactgccgt cacaatccaa tatctgcgaa
     9001 gtgaagtaat cgattcgaaa tcgctcgatt ttgtcagaac agcccgttcc aaaggggtac
     9061 cgacgaataa agtattcagt cgacatattt tccgaaatgc agcgttgccg atggcttctc
     9121 aaatggggta tgaaatcact tcgttgattg ctggttctgt agttatcgaa aagatttttg
     9181 gttatccggg agtcggaaaa ctatttattg attccatcgg ccaacgggac tataccgtga
     9241 tcacatcctt agtattgatt ttaggaatcg cgacgctagt ggggacatta ctttcagata
     9301 tcatcatgag tatcgttgac ccgcgtattc ggattcaata aaaccaatca gaaaggagaa
     9361 tggatcgatg agtgaaaaaa acaatacagc agttcaagaa agtattcctc ctatggggat
     9421 acgaatgatt gctcgagaat ttaaaaaaga taaaattgct attttttcat taggtttgct
     9481 agtggtttta ttattagtga tctttatcgg tgcgatgctg accgatcaag acaaagtgat
     9541 gtatgttagt atcttcgaca aatacgctgc accaggaaca gtttcgacac aaggacaaaa
     9601 gttcattctg ggagcagatg aaggcggacg tgatgtatta ggacaattga tcataggtgc
     9661 tagaaactct gttacgatcg gatttgcgat cacgatcctt acttcgatca tcggggttgg
     9721 attagggatc atctctggct actacggagg gatcattgac aacatcttga tgcggatcgt
     9781 tgattttatc atgattctac cgatcatgct gatcattatc gtcttcgtat cgattatttc
     9841 cagatacaat gtctggtcct ttatattcat catgagtgca ttttattggg tagctaaagc
     9901 ccgattattc cgaagcaaga cattatctga agcaagaaga gattatgtca gtgcctcaaa
     9961 aacaatggga accaatgatt ttaaaatcat gttccgcgaa atcatgccga atctaagttc
    10021 attaatcatt actaatttga cgatgaactt tgcggcaaac atcggtatcg agacaacttt
    10081 gactttctta ggtttcggct tgccggcaaa tgtacctagt ttaggtacat tgatcggtta
    10141 tgcaagtaac ggagaagtct tagtgaatcg gcaatggatc tggttacccg catcaatcct
    10201 tattttagtt ttgatgttga gtatcaatta tgttggacaa gcattcaagc gttctgcaga
    10261 tgcgcgccaa cggttaggct agtatagaag cgaaggggga aataggaatg aagaaaacga
    10321 tttttggatt tgcagcgctg atgtctgctg tcgttcttgc agcatgcggg ggcggaggta
    10381 cagatacctc tggaaacaac tctggaggca acggcaataa caaagaggaa ttaacttttc
    10441 caattgcaac aaaaaataat gatgatgcaa tcgaagacgg cgaattagaa gctgcggtcg
    10501 caacggacag tcagtttaaa ggattgttcc agtgggagtt ttaccaagat tcatatgatg
    10561 cagcttttat ggctccttct catgaaccgc tatttgcaaa cgatgacgat ttcagaatca
    10621 cagacgacgg agctgcaacg cttgatctag atgaagatac gaaaaaagcg acaatcaaag
    10681 taaaagacaa cgtcaaatgg tcagatggtg aagatgtaac ggcggacgat gtgattttcc
    10741 cttacgaaat cattgggaat aaagattaca ctggtatccg ttatgacgac actttccgta
    10801 acatcgtagg tatggaagaa tatcatgatg gaagtgccga cacaatctcc ggaatcaaaa
    10861 aaatagacga caaaacagtt gaaatcgaat ataaagaagt aaacccaagc atgcttcaat
    10921 cgggtggtgg tatctggtca tatgcagcac caaaacatac gttagaaggt gtagcaatca
    10981 aagatatgga atcaagcgat caagtacgta aaaatccagt gacttttggc ccttattaca
    11041 tgagtaatat cgttgcagga gaatcagtag aatacttgcc aaacgagcac tactggaatg
    11101 gtacgcctaa attgaaaaag atcacgatga aatctgtacc gatggcaagt gcaactgaag
    11161 cattgaactc taaattatat gatatgattt tccaaatgcc aacagatact tacgatacct
    11221 ataaagaaat tgctggctat acaaacttag gccgtgaaca aacttcttat acttatctag
    11281 gattcaagtt aggtaaatgg aatgcagata caaagagtgt ggaatacaat ccagattcaa
    11341 aaatggctga taaatcatta cgtcaagcaa tgggctatgc attagataat aatgcagtag
    11401 gtgaacgttt ctatgcaggt ttgagaagca atgcgacttc attgattcct ccagtattcc
    11461 agtcatacca tgatgatgag atgaaaggat tcacacaaga tctagacaaa gcgaaaaaac
    11521 tattagatga tgctggctac aaagatgtgg atgacgatgg tttaagagaa gacaaagatg
    11581 gaaataaact aacaatcaac tttgcttcga tgtccggtgg ggaaacagcg caaccattgg
    11641 cagattacta tatccaacaa tggaaagaaa ttggtttgga tgtccaatac acaacaggtc
    11701 gtctgatcga attcaattct ttctatgata aattagaaaa cgatgatcct gaaattgatg
    11761 tttaccaagc tgcttggaat acaggaactg atccaaatcc aagtggacta tggggaccaa
    11821 atgctgcgtt caactacact cgttatgaat cagaagaaaa tacaaaattg atcaacgata
    11881 tcagttcaag caaagcattt gatgaagagt accaaaaaga agcatatcaa aaatggcaac
    11941 aatatgcatt tgaagaagca tttgcgattc caacgttgtt ccgtaatgaa gtattgccag
    12001 tcaacgaccg tgtcaaagac tgggattggt cttatgatgt accaaaccca tgggcaaatg
    12061 tttctgttac agcagattca cgttcataat cactaaaaat gaccgaaaaa gggcgatgtc
    12121 ctttttcggt tttttgatat ttttctgttt atttctctaa tattcaggtc aaggcgctga
    12181 tttcatgact tctccaataa acggtgttca aagtccagtt tctcggtatt aagtcaaatt
    12241 tatgcaaaaa tatggaaagc cattttcaca aaattttttc ttcatactcg aaactaaacg
    12301 aatttttcac aacttctcgt caatcactag gattattaaa gctttactta ccttttgacc
    12361 gaaccatttc aaatttgaca aaaaaccagt ataataagga agtatcgaaa aaatatccat
    12421 aaaaggaatg tggaaaatgg acaaccagct gacaaaagaa ctaaaagaaa actataacat
    12481 cgtttttcac gatctaaatt tgcttgaaca agcttttacc cattcatcct atgtgaatga
    12541 gcatcgcaat ctgcaattat cggataatga gcgacttgaa tttttaggag atgccgtttt
    12601 agaactgatg gtttctcagt atttattccg tttatatcct catttgccag aaggaaaatt
    12661 gacaaaaaca cgagctgcga tcgttcgcga agacagcttg tcgaaatttg ccaaagaatg
    12721 tcactttgat caatatgttt tgttgggcaa gggagaagag aattcaggag gacgtacgcg
    12781 accagcattg ctttgcgacc tattcgaagc ttttttaggc gcgttatatc ttgaccaggg
    12841 attcgacacg acccatgcat tcatcgaaaa agtgattttt cctaaagtca aagcaggtgc
    12901 tttttcacat gagatggatc ataaaacaaa actacaagaa gtcttgcaaa aatcaggtga
    12961 tgtatcaatc gaataccgat tgatcaatga agaaggtcca gctcatgaac gagtattttg
    13021 gatcgaagtt tatgtagatg atcaattgat tggcactgga caagggaaat cgaaaaaatt
    13081 agcagaacaa gctgcggcgg aaaatgcatt ggcagcactg taaaagtaag tgagggaaag
    13141 ctttgtattt gaaacgaatt gaaatagccg gttttaaatc atttgcagac aagacagtca
    13201 ttgattttga aaatagcgtc acagcagtgg ttggaccaaa tggcagcgga aaaagcaata
    13261 ttacagaggc tatccgctgg gtattaggag aacaatctgc taaaagtctg cgaggcggaa
    13321 aaatgccgga tatcatcttt gccggttccg atacccgtaa gcagctgaat attgcagaag
    13381 tcacagtgat tttagacaat agtgatcatt atctgccatt ggagtacaat gagatcagtg
    13441 taacccgccg ttatcgacgg actggggaaa gcgagttttt catcaataaa caaagctgca
    13501 gattaaaaga tatccaagaa ttgttcttag attctggatt aggaaaagaa tcgttctcaa
    13561 tcatttctca aggaaaagta gaagcgattt tcagtagtaa accggaagac cgtcgtggga
    13621 tctttgaaga agcagctggt gtcttgaaat acaagcagcg gaaaaagaaa gcagaacaga
    13681 agctttttga aacagaagac aacctcagcc gcgtccaaga catcatccac gaattggaag
    13741 aacagttaac tcctttggcc gcccagagtg aggcagcaaa ggagttttta cggctaaaag
    13801 aaacactgac tcaaaccgat gtctctttga tggttgctga aatcaagaca gcaaaaaaag
    13861 attgggacaa caaacaagca cagcttgcga aattcaatct agaattaggc aaactatctg
    13921 agtcgatcca agaacaagaa tccattttgg cgaagcagcg taaagaaaat gcgcaagccg
    13981 atcgtctgat cgaaaaaaat cagcaagtat tattagatct ttcggaaaaa ctgaagcaga
    14041 cagaaggaca aaaagatgtt ttgcaggagc ggacaaagca tacacaaaaa agctcgcaag
    14101 aatatcaaac ttcattagca gaagcacaaa aaaaggttaa acattttgaa aagcttcaag
    14161 aaagcttgat gaaagcagca gcagaaaaag aaacagagat ccaaaaagct gaagcaaatc
    14221 tcataaaaac acagcaagaa ttagaaaaat accaaaaatc aacgaaagaa ttattggcag
    14281 aattaagaga tcaatatgtt gatttgatgc aagaacaagc agctgtagga aacgaactga
    14341 agtatctaga acgtcaatat atacaagaaa cagcaaaaag caagcagacg ttagccaagc
    14401 aatcggaagt agaagcatca gtagaccgat tgatcttaca aaaagaagaa ttgacacaaa
    14461 agcaggcgca gctaaaatca tctttaactg aaacaaaaga gaagttagaa atgatccaac
    14521 aaaacgggaa aaagttccaa gaagcattag caaaagaaca gcctaaaatg tatcaattaa
    14581 tgaatcaagt ccagcagcta cgtgctcgta agaaaagcct tcaagaaatc caagaaaact
    14641 attttggttt ttaccaaggg gttcgattgg tcttgcagca taaacagcag ctttcgggta
    14701 ttgtcggagc agtggctgaa ctgatcgatg ttcctgcaga tttcacgtta gctatcgaag
    14761 cagctttagg tggggcagcc cagcatgtca tcgttgaaaa tgaaaaagat gctcggcaag
    14821 ccatcacgta tttgaaacag caaagaggag gaagagcaac attccttcca ctgacgacaa
    14881 tcaaaccaag acaattaccg gctcatatat tgacacaagc agcagctgta gaagggttta
    14941 tagggattgc cagtgaacaa gtcagttatc ccgatcaaat ccaaactgtg gttcaaaacc
    15001 tgctaggaac gatcctttta gccaaagact taactagtgc caatgcaatc gcgcaaacga
    15061 tccgctatca atatcgagtg gtttccttag aaggtgatgt gatgaatgcc ggaggatcca
    15121 tgacaggtgg agcgaataaa cgaggaaacc aaggcagttt gtttgtacaa aatcaagaat
    15181 tgaaacagtt gactagtgaa tttgaagaag cagataaaca actccaagca caagaaaaaa
    15241 aagttcagga gctgcaacaa gaaacagctc gtttagccga agaacaagaa gttttgcgta
    15301 cacgaggcga acaattacgt tttgaagaac aagaagcgac aaatcagcta caaaacatca
    15361 taaatgaact tgaacgtttt gaaaaagaaa agcaaatctc aacttttgag acacgtgaac
    15421 tgcagcagtt tatcgaagat tacgaaaagc aaacgaacga attgaaagac aaacaaacag
    15481 atcttgaatc gcaacgacaa aaaatcgacg aagaaatcaa atcgttaagt caagaaagcg
    15541 accagatgga agccagaaga gcacaagtac aaagtcaaaa agcacaagaa caagcagatc
    15601 ttgctgtctt gaaagagcag tttaatcatc tgcagatcca gctccgcggt gcccgagtcc
    15661 aaaaagcaga ggcaaccgaa cgtcaagaag cgatagaaaa gcagttggcg acattgacag
    15721 cagacttttc tgatcatgaa gtcacagaag aaagtttgga aaaacaaatt aacgaattat
    15781 ctgctcagcg agaaacatta aaagccgagt tggcaaaagc caaagagcag cgagatagaa
    15841 ggcaaaagga gatcgataag cttgaagcag tcttggcaga gcgtaatcgt gagcaaaaag
    15901 cacgactgtc ggaacaatcc aaattagaag tccaaaaaga ccgagctgaa atgattttag
    15961 ataatcattt gacctatctg cagtcagaat atcagctgac atttgagaaa gcttcccaag
    16021 actatcaaga aacaaccgat atcgaagaca gtagaacaaa ggtttcatcc ttaaaagaac
    16081 agattgaaaa actgggacca gtaaacttaa attcaatcga acaatacgaa caagtcagtg
    16141 aaagacatac attcttagca acacagcgag atgatctgtt agcagcgaaa aaccaattgt
    16201 ttgaaacgat ggatgagatg gatgatgaag tgcggacaag attcaaagaa gtatttgaag
    16261 ctatccgtca agaattcaaa attgtctttc caaatatgtt tggcggcggt aaagctgaat
    16321 tagtactgac ggaaccaact gatttgctga aaacaggtat tgagattgaa gtacaacctc
    16381 ctggcaaaaa actgcaaagt ctaagtttgc tttctggagg agaacgagca cttacagcca
    16441 tcgcgttgct cttttccatt atccgtgtct gtcctgttcc gttttgtatc ttagatgagg
    16501 tagaagcagc gttagatgaa gccaacgtga aacgttttgg tcgttacttg agcgatttcc
    16561 aagatgacac acaatttatc gtagtcacac accgcaaagg aacgatggtc gcagcagatg
    16621 tactgtacgg agtgacgatg caggaatccg gtgtatcaaa aatcgtttct gtacggatgg
    16681 aagatatcaa tgaagaggcg aaaatcaacg aaacgaaagt gtaggaacga aaatgatcaa
    16741 attagtagca atcgatttgg acggtacatt attaaatgaa caaaagctga tttcagatga
    16801 gaataaacaa gcattagcac aagcaaaaca gcaaggggtc aagatcgttc tatgtacagg
    16861 acgcccctta gctgcgatgg cgcattatct gcaagaatta ggactggtag atgaaggtga
    16921 ctacagcatc actttcaacg gcggtttggt acaaaaaaat gatactggtg aaatcatgga
    16981 aaagaaagtg atggaagtat cagatatcca acgcttatac aaactggctc agcaattgga
    17041 tctgccacta gatgttttgt ctgacaatgt ggttttacag ctgcctagtg ccccaaggaa
    17101 gcaatccttg tacaatgtgt tgaataagct gctgcaattc caaccagcgg atataagcga
    17161 tattacagat gaatttgtgc ttaataaggc agtaatcgct tatgaccaag aagaattaga
    17221 tcctaaaatc aaagaaatac cagcagaatt ccatgaaatg tatgagatca tcaaaacaag
    17281 aagtatgctt ttggaattta tgccaaaagg tgttacaaaa gcttatggta tttctttatt
    17341 ggcaaaagat cttggtttga aacaagaaga aatcatggcg atcggtgatg aggaaaatga
    17401 tttaccgatg atccaatatg ctggactagg cgtagcgatg gagaatgctg tgcctttcgt
    17461 caaagaagca gcagatttcg tgacagccag caatgaagaa aatggcgtag ccaaagtgat
    17521 ccaaaaattt gtattagagt agggggagtc aaatgggatt ttttgataaa atcaagcgtg
    17581 cttttactgg cgaagagaaa acagaagaag ttgaagtaca ggagaagtac gacaagggtt
    17641 tagaaaagac gcgtaaaaca tttggtgaac ggatgaatga gttgtttgcc aattttcgaa
    17701 cagtcgatga agactttttt gaagaattag aagaaacact tatcggtgca gatgtaggtt
    17761 ttgaaacagc gatacgaatc accgaagcat tacgtcaaga agtgaaactc agaaatgcga
    17821 aaaaatcggc agaagtccaa aatgcgatca tcgagaaact tgtggatctc tatgaagcgg
    17881 aaggaatcaa tgaagtaaat gaactaaata tccaagaaga cggactaaca gttattttgt
    17941 ttgtcggtgt taatggtgta gggaaaacaa caagtattgg taaacttgcc catcagttca
    18001 aaaacgaagg taaaaaagta ttgatggcag cagcagatac cttccgcgct ggagcaatcg
    18061 accagttagt tgtctggggc gaacgcgctg gtgttgaagt tgttcgtggc aatgcaggag
    18121 gcgatccagc agctgtcgta ttcgatgctt tggaaagagc aaagacagag caggcagatg
    18181 ttttactagt tgatactgca ggccgactgc aaaataaagt gaacttgatg aacgaattag
    18241 aaaaaataaa acgagtaatc cagcgggaat taccagaagc accccaagaa acacttcttg
    18301 tattagatgc aaccactggt caaaacgcga tggttcaagc aaaacaattc aaagaaacaa
    18361 cagatgtgac cggtcttgtt ttgacaaaat tagatggtac agcaaagggc ggtatcgtac
    18421 ttgctatccg taatgaattg catttaccag tgaaattggt cggtcttggt gaaggaatcg
    18481 atgacttgga gccgtttgat ccaaatgatt ttgtcgttgg attgttcaaa ggattactaa
    18541 aagaagaata acccatgtct aaaaagcagg agctgtgaca aaagttgcag ctccttgttt
    18601 gaatgattgt ttttaacata gctgtgtttt tgatgccttc atttttatac ttatttgtaa
    18661 gcggttctca aacaatttcg ttctttttct tagacttttt gattataatt agattcatat
    18721 gaattggagg tcacttaatg atgaatttta agcaattatt attgcatgtc aatgcgcgcc
    18781 cttttatcga ccaagctcga tttggtatag aacgggaagg acagcgggtt gatcttgcag
    18841 gaaatctagc aaaaaccgat catccagcaa tctttggcga tcgatcctat cacccctata
    18901 tccaaacaga ttttagcgaa acacaaacag agatgatcac ccctgttacc gattctattc
    18961 ccgaattatt tcagtatctc gctgctgttt atgatgtgac tgctcgttct ataccgaaag
    19021 aagagatgat ctggccatta agtatgccac ctgccttacc ggaaaaagac gaagagatca
    19081 ttattgcaaa attaaaaaat ttcgaagatg tcttgtatcg acgttattta gcaaaaaaat
    19141 acgggaagcg aaaacagatg gtaagcggta ttcatttcaa ttttgaattt ggcgatgagt
    19201 tgctaagaac attgttcagc catcaggaag aatttcaaga tttttccgaa ttcaaaacag
    19261 aactttattt gaaaacagcg agaaacttta tgcgctatcg ctggatgatc acttatttat
    19321 tcggtgcttc accaatgagt gagaagaact actttttaga tgaatcacat ccgcaagaac
    19381 ctgttcgcag tattcgcaac agtgcgctgg gctatacgaa tcatccaaat gtgaaagttt
    19441 cctatgcttc tatgaaacag tatttagcag atatcgagcg aatgatcgaa gaagggaaac
    19501 tttcggagga gaaagaattt tatacaccgc ttcgtttccg aggcggaaag aaagtcgcag
    19561 atttagcaac aacaggtgtt cgttatattg aattgcggaa tatcgatttg aatccttatg
    19621 caagattggg tatcaatcca gagcaagttc ggttcttaca attattcctg atgtacatgt
    19681 tatggacaga agaaaaagaa gactgtgacc aatgggtagc agaaggtacg actcgaaata
    19741 acaaagtagc actagaacaa ccatcagatc aaacagaatt tcatcaagaa ggtagagaaa
    19801 ttcttgaagg aatgaagcaa atgctggttg aattggattg gttggattct ctttatttag
    19861 tagaggaagc attgactcaa atggatcatc ctgaacaaac gttagcagcg aaactctatc
    19921 aagaagcaca gctatcgagt cagcaagaag ttgctgtggc attgggacat caatattata
    19981 aagaaagcca tgaacgtccc tatcagttgg ccggttttcg cgaaatggaa ctttctactc
    20041 agatatttat gttcgatgcc atccaaaaag gtgtccaagt caaagtatta gatgagtcgg
    20101 atcaattttt gcgtctgcaa ttccaagacc atgtagaata tgtgaaaaat gcaaacatga
    20161 caagtaagga cagctatatc gtcccactta tcatggaaaa caaaacagta acgaaaaaag
    20221 tcttaaaaga agctgggttc cgggtaccag gaggcgcaga attttcatcc atggaagaag
    20281 cggtaaaagc ttatccgaga tttgccgagc aggcatttgt gatcaaacct aaatcaacca
    20341 attacgggtt aggtatcacg attttcaagg aaggagctag tctggaagat tatcaagcag
    20401 gtttagccat tgcttttcgt gaagacagtt cggttttagt agaagaattt atgccgggaa
    20461 cggaatatcg tttctttgtg atcgacggag aagtccaagc catcatgttg cgagtccctg
    20521 ctaatgttat tggtgacagt atccgaacag tgaaagaact tgttgaagaa aaaaatagtg
    20581 accctttgcg tggaacgaat catcgtgcac ctttagaatt gatccaatta ggtgaattag
    20641 aacaattgat gttgaaagaa caagggttga cgatcgaatc agttccccaa gccaatcaaa
    20701 ttgtttatct aagggagaac tcaaatatca gtacaggtgg tgattcgatc gatatgactg
    20761 atgaattttc tgaagcttac aaaaaaatcg ccgtttctgc ggtagaagca ctaggagcta
    20821 agattagtgg tatcgatttg attataccag ataaagaaat cgatcctaca actgataaaa
    20881 aagcatatgg gatcatcgaa gcaaatttca atccagccat gcatatgcat gtttatcctt
    20941 ttgcaggaaa aggcagaaga ttgacgatga atgtattgaa attgttatat cctgaagtat
    21001 tttaaaagaa aaagcttttg acagattgtc ctatttgatg tcaatctgat caaaagcttt
    21061 ttttgcatgt aaaaatttat gtgttttttc gttttaaaat aaacgatccc agaagctttt
    21121 tttctttttt ggtttttctt tttcagctgg cgaagagttt tcttctgggt attttttttc
    21181 gatatcaatc acaggttcat ttactgcttc ttttgctgtt aagagcaatc cgaattcctc
    21241 aggatttgca gtgacgtaat cgttgactac agtgaaacgg ctattgtttt tcgttgctag
    21301 ctggatatat tggttttgga cagaaagggg tagagcccca ttcaagagta tggaagcatc
    21361 tggatgtttt ttgagttctt ttaaaaagtt ttctttgttt tttggttgga tcatttcagc
    21421 aacagtcata ctaagatagc agcgttccct gaatgtccct aaatatttat gctgttcttc
    21481 agggttcact aaaggtgtac cataaagtcc cttatccaaa tggcttttta catcatcttg
    21541 tgccataaaa aataccctcc ttcttctctt tgtctttctt acgattatag catattccca
    21601 ataataccta aaacatatga aaaagcggtt gcttttgttc aacgattcac ttaaaataag
    21661 aatgaaaatc attctcaatt agaaaggtgg attggatgcg ctacggacga ctagtagcat
    21721 tattagttat tttaagtagt atttcattgt tcatcggagt atcgaatgta caattgtcag
    21781 aactgctcca gttagatggg caaagcttac aaatcttgct agtgactcgt ttgccacgaa
    21841 cgatttgttt gatccttgtg ggagcgacca gtagtatttg tgggttgatc atgcaacatt
    21901 tgacccaaaa taaatttgtt tcaccaacga ctgcgggcac gatggatagt gcgcgtttag
    21961 gtattttagt ggctatgatt ttcctacctg gtgcatcctt gattgtccga tccttgacag
    22021 cattttgctt tgcttttgca ggaacattgc tttttttatc ccttacgcga ttgttcctcc
    22081 agaaaaatca attgatgctt ccgttgattg gagtcatgtt agggaatatc attggttcag
    22141 ttgctacttt ttttgcttat caattccagt tggtacaaaa tatgacttca tggcttcaag
    22201 ggaattttgc gactgtgata cgaggaaatt atgagttatt gtatgctgtt gttccattgt
    22261 tgctcttggt ttggctattt gcttaccgat ttacgatcat tggtctgggc gaatcgtttg
    22321 cagtaaatct gggaatagat taccagaaga tgcagttttt aggcattggc ttagtatcat
    22381 tggctagtgc agtcatgttg atcatggtag gaagcattcc ttttatcgga gtgatcattc
    22441 cgaatcttgt ctctagaata tatggagatc aagtgcacaa aacaattggc gtaactgctt
    22501 tagcaggtag tttgttctta gtattttgcg atcttgtcgc tcgcgtgttg atttttcctt
    22561 atgaaatacc agtcagtgtg atcgttggaa tcatcggtgg ggctatcttc ctttatcttc
    22621 tgataagggg acgacgatat gcttaaaaaa aagccatcta tttttattgg tatgcttgtt
    22681 cttgttttat ttgttacagg aatgtacttg acgatccata catatggaaa ctggcatttt
    22741 gcatgtgcat tgaggagtaa gaaaattttt gcatttatcc ttgtctcgct agctgtcagc
    22801 agtgccacaa tcagctttca gacaattacg cataaccagt ttttgactcc ttcagtattg
    22861 ggacttgagt cgttatatgt ccttgtccaa acggtccttt tcttctttat cggaggagtg
    22921 acgatgcttc agcagacagg tacagttttt ttcttattga acgttgggct gatggtcggg
    22981 ctgagtctat tgttattttt ctttcttttg aaaaaaatga gagcgaatct ttttttatta
    23041 ctgatgtcag ggatgatttt aggtacgctt tttggtagtg tcagtacctt tttacaagtc
    23101 atcatggatc cgaatgaata tgatttgctt caaggcagat tatttgcaag ctttggcaat
    23161 atccagagtc agtatctttt gcctgcttct ttgatcatta tcggctgctg gtacctgtta
    23221 tttcgatatc gacatgtgct agacgttttc catctcggaa atgaacaagc agtaaacctc
    23281 gggatagaca cagatcgttt tgaatttttg attttatgtt gtgtcagtct tttgacaggg
    23341 acatcaacgg ctcttgtggg tccagttact tttttagggt ttattgtcgc aaatatcagt
    23401 tatcgtgtct tttctactta tcgtcatggt cagctattta tcggaagctt tctggtagct
    23461 atgctgtttc tgacaggagg acagctcgca gtagagcaga ttttcggctg gaatacaaca
    23521 gtgagtgtcg tcgttgaatt tgtcggagga atttattttg tcacaaaatt gattcgcgaa
    23581 aggaagagta tcctatgatt gatttacaaa aggtcaataa actgtaccat ggaaaatcag
    23641 tggttaaaga tgtacagtta acgattcctg aaaagaagtt gactgctttt atcggtccaa
    23701 atggtgctgg aaagtcaacg gtgttgtcga tgatcagtcg tttgatacca aaagatacag
    23761 gtgaaatcta tttagaccat aacgaagtaa aggcttggaa atccaatgaa ttagccaaaa
    23821 aattatcgat cctacgacaa tcgaatgaaa taaatgtcca aatcaccgtg aaagaattag
    23881 tagaatttgg acgatttcct tatacgaaag gaaaattgac gacaaaagac gaggaaatcg
    23941 ttcaggaatc actggaacac cttgggttag aagaaatagc ggatcaatcg attgacactc
    24001 tttcaggcgg tcaactccaa cgtgcgtata ttgcaatggt gctagcgcaa gacacggatt
    24061 atattttact ggatgaacct ttgaacaatc tagatatgaa ttttgcggtt caaatcatgc
    24121 agattttaaa aaatttagta caagaaatcg ggaaaacaat tgttattgtt cttcatgata
    24181 tcaactttgc tgcaagttat gcagacgaaa ttgttgcaat gaaagatgga cagttattta
    24241 cgcaaggaac gacccaagaa atgataaaaa aagatgtatt ggatgaatta tacgaaatgg
    24301 acatacggat ttgtgagatt gaaggccgca gattctgtct ttatttctaa aactaacatt
    24361 aggagagaag agatgaaaaa attagtagta ggtatcttga ttctagcatc atttggttta
    24421 gcagcatgtg gaaatagcaa caacaccagt caggcagaca caaaaaaaag cagcacacaa
    24481 actgaaacta cattgacgat aacagatagt aatggagacc aaatcgaggt gccaaataat
    24541 ccagaaaaag tcgtcgtatt cgacaatggt tctttagata cgatggatgc tcttggtgtt
    24601 ggagataagg tagttggagc agctacaagc agccttcctg agtatctttc atcctataaa
    24661 aaagtagaat cagcaggtgg aataaaagaa ccagacttag aaaaaattaa tcagcttcag
    24721 ccagatctaa tcatcatttc tggccgacaa agagattttc aaaaagatct aagtcaaatt
    24781 gctccgacca ttttcctttc tttagatgcg aaaaatccat gggaatcttt ccagcaaaat
    24841 gtcactgctt taggggagat ctttggtaag caagaagaag ctaaaactca attagaggaa
    24901 ttatctagtg caatcgatca gacgaaaaag aaagcagaag ctactgacaa aaaagcacta
    24961 gtcacacttg tgaatgaagg gcaattatca gcctacggat ctggttctag attcggtttc
    25021 atccatgatt tatttggctt tgaacaagca gatgatcaaa tcgaagcatc cactcacggt
    25081 caaagtgttt cttatgaata tgtgctggaa aaaaatccgg atatcttatt tgtagtagac
    25141 agaacaaaag ctattggtgg agacgacagc aaagatgata tttctgccaa tgaactggta
    25201 gcacaaacga atgctggtaa aaatcagcag atcatctccc ttgaaccaga tgtctggtat
    25261 ttaagcgggg gcggtttaga atcaatgaaa ctgatgatcg aagatgtgaa tcaagcattt
    25321 aaatagcata aataacagag gattaaactc tcatactatg taacaataat gtttcttaca
    25381 ttcttaaata gcaagagcct atcctcaaag aagttatcaa aaaccatccg taaaatcgta
    25441 ttgatgattt tacggatggt ttttatttat ttgagaaatc ttttttcaac gtgaattcat
    25501 tatctacatc atacgggttg attctagaat ggggagtggc aaaaaatagt gtgatccatt
    25561 ttttcagcat caagatcgcc tcctttgatt tgaatcaaag gtacaaagcg aaacttagat
    25621 aaaacttaaa tttagatatt tttattttgt accgatctct tctttaaacg atgttccatc
    25681 tgctgcttct cggcaataag tccactagac tagaaaatat gagaagctat tttctgtcca
    25741 gcgttcttat tactcaaaac aaatcgcagt tgtcacaatc tcttctaaac gatgttccat
    25801 ctgctgcttc tcggcaataa gcccactaga ctagaaaata tgagaagcta ttttctgtcc
    25861 agcgttctta ttactcaaag caaatcgcag ttgtcacaat ctcttctaaa caatgttcaa
    25921 tcagctgacc ttcggtatta gctcaaagca ctgatttcac aacctctatt taggcatgtg
    25981 tctcagcaag cggttgatag ttgatgatct gcatttttcg ataaaaatcg gcgggaagct
    26041 tactccaccg ttttagtaat tgatagaaat aactctcttc tgctttgatt ttatactcgc
    26101 ttaatatcaa tccaaaacta ttcgtttttt ttgaagctaa ttttttataa atatccaatg
    26161 ctttggtttt atcttcattg acaaagagtg tttttacttc aatataagaa ccctcgatat
    26221 tttgtgtttc ttcgataaaa tagatgtttt ttatatattc cttcatagtg attcctccaa
    26281 agaagtcttt tatttgataa gtttactcta ccgaagagtt gttaataatc cgtgaacaaa
    26341 aagtaattct ttttccaata gttgttaaag gttttttatt ttttatagta ttttttgtta
    26401 tttaagaaag gaataaggtt aaacaaataa caggttgctt tttgggtctt tttccgttca
    26461 agaaactgaa cgaagaaaag ggaaagttgt ctcttttgtg ataagagaaa tcataataaa
    26521 cgaatgactt actttccaat aaattgagaa cagtcagaac cagacaaatt agttgcatct
    26581 gatgaataaa gtgattattc tatgacatga ggtgatacag atgaaattag aagtgacaaa
    26641 agaagcacaa gaagtattga agaataaatt agaagcagac gatcaacttt tattagatat
    26701 cgaaaacggt gacggtccat ttgcagaaag ccaagtcagt tgccaattgg atacggcatt
    26761 tcgattgatc attgtcaaaa aagatacaca aacagatcta agtctttatt ctgtagtggc
    26821 tgatacacca gttggaccaa tcaaaatcaa agacagtgca atactttaca tggatgatcc
    26881 atccacactt gctttagaac caacttataa tagtttacaa ttaaaaggac caagcggctt
    26941 gagaaaaggc aacttgcaag ttgttcgaaa agactagagg gataaaatgg gaaaattggc
    27001 gatcatcagc gacctacatg tggacatcaa taaattcggc gaatcagagc tgatgcagct
    27061 ttggcaagtt ttgcaaaagc acaagatcac tcggcttcat ctagccggag atacggctaa
    27121 taaagtagac cgttgcctag ctgttgtcga atttttcgtc aataaaggat tatctacgac
    27181 atttcatttc ggcaatcacg agttggcaga tgtgcccaat gaacagatga tggaccattt
    27241 tccagaccca cattttttaa atgaacggta tattgcttta aatgagcaga ccgttctttt
    27301 agggatgaat ggctggtacg actatcagtt ttccgaattg aaagattacg aggcaatcgt
    27361 acgaatgaag cgtttgtatt ggtatgatcg gttcatccag cgtgggaaaa cagatctcga
    27421 ggtcaatgca gaaatgcttg cagctgcaaa aaatttgcta gaccagctgg aagcaaaaaa
    27481 acttgaggtg attttatcca ctcatttcgt tcctaaacgg gcatttatca tgtatcaatc
    27541 tgctccttat gagcgttgga acaaattaaa tgcattttta ggatcagaat cattcggaga
    27601 attacttgac cgttattcaa atatcaaaca agtagttttt ggccatacgc atcgtcgctt
    27661 tgaagataaa tccatcggtc acacgattta cagctgcaga ccttttggtt attattatga
    27721 atggcagctg acccgagatt ttgtcttgaa agaacagttg ctagacagct atgatcctat
    27781 gaaattacgt gtcctcttgc gtgcccatca cccagctttt caggcctatc aaacacaaca
    27841 tttgcaagag gaatttgaac aagcgatgac aatcgttccg tattgagaca gcattagtaa
    27901 tgtgtaaaag aaaatacctt gtaaaacata aggataagta agagcagtag atccatttat
    27961 cgtggatatg ctgctttttt tgcggaaaat aatcagcgaa tgtttatttg atcggatgat
    28021 ttgtaactcg cagagtacta gatgcaagcg tgtattcttt ttttgaacga taatcacaaa
    28081 aaaaaatata atatacattt tttatttaat tataattaat attgattgaa gtctaggcag
    28141 tcaagtcaca ttttgataga taggaggggg acttacgaat tattttaaag gctatgacag
    28201 ctgtatttct agattgtgtt tgcatcaagt tgcaataaaa actagaaatc aaatcgggct
    28261 gataatcatt tataactaat cgatacatag gaccaaatat aggtctatgt tcttttattt
    28321 cataagtatc gtaaaacaga attttgctat ggattaatcc aatcgactga tatgtttagt
    28381 aaataaagaa agaggaatgt caatgatgaa aaaagaaatc gtattaacag cagcaatgat
    28441 gttattcagc atggtagcaa gtacgacttt tgtttctgca actgaagtat acccaaagga
    28501 atataacaca gaaggaacga ttacatttga agcaggagat gagggtgtaa ctcctcctgt
    28561 tgatccagag aatcctgatc ccaataaacc tgtcgatcca tcagatcctc caagccctgg
    28621 aacaggaggg gcattatcga ttgattatgg atcaaaattc aaatttggga ctcaaaaaat
    28681 ttctactgcg gataaaacgt attatgcagc tgctgatgtg atgaacgatg ggtctagaaa
    28741 accgacatat gtccaagtga cagataggag aagtacctta tctgggtgga aattaagtgt
    28801 ctctcaacca gaacagttta aaactgccag tggggatgaa ctagttggag cacagctgaa
    28861 atttacgaaa gggcaggctg tttctttggt tgatccaaca tatacgccgc aaacggtgaa
    28921 ttctgaatta acgttgacac cgggaggaaa caatacgtta gcaattaatg ctaaatcagg
    28981 aacaggtgtg gggacttggg tctatcgatt tggtgcaaat gaaaatgaaa atcaagatgc
    29041 ggtacagctt tcggtacccg gtaaatctgt caagttagcg caacaatatt ccactaaatt
    29101 agtttggaca ttagaagata cacctaacaa ctagtttact gaaaagaact gttaaaaata
    29161 aatacgtagt catattgtct tgcgaggtaa tcgagcaaaa attgtcaaag gctaggctaa
    29221 atttgtttgg atacgaatag ttcatctagg aatttaacga tcaggaggaa aagatatatt
    29281 gaaaaagagg aggatcgtgc tcattttaag cagtctctta gtgactaata tctttccgat
    29341 catagggtac tctttggaat tgaatcagtt ggagcatgga aatagaagag acgaagaaag
    29401 caaactcact tcgacattcg acagtttaat agaatccaac cagacacaag aaagcagtga
    29461 ggatttaagt atttcgagta gtggagagac cactgacaac gtagaagctg agggttcgga
    29521 caaacaagga ctagaagatg caccaatttc tgcggttgag ctgcctgacg atcccaatat
    29581 tatttctatc gataaaattt ttcaaacacc tatcggtact agcacgtcca tattggaaaa
    29641 tgggaagtta ctgcagttga acccagcaga aaggtctcaa agaggagcta tttggtcaaa
    29701 taagaagatt agtttactct cggattttac atttaaatct tatttatact taggaaatca
    29761 acgagataga gcgggagatg gcatgacctt tacattgact ggcgatccta gaatggctag
    29821 taatcccagt caagttattg gatcgccagg tatgggaatt ggctcatatt ctactcgttc
    29881 tggccaacct tacattgcga atgcgctctc gattgagttt gatacgtata aaaatagtgg
    29941 ttcttctgat cgaatggatc gagagataac tgctgataat agagggcatg gacatgtcgc
    30001 ttttgtcacg cctaaaccaa ataataataa ttattctgga gagcatactg gcgtgacggt
    30061 agctcctaca tttctttcta atggcacatg gcgcttgtta ataattaaat gggacgcgga
    30121 gcaaagaagt cttacttatg atttggaagg tgtcggtcgc tcttctcgga ttatacctga
    30181 tctcattagg cagtttggtt ctacagaagt aaattggggg tttacttctt caacaggtac
    30241 tttttttcaa gaaaatgctg tcgctgtcac gcgacttcca tcgaatgtca catcaacagc
    30301 tgatgtaaaa gtcaacgata gtgattatgg ggccatcgct gaagctggag gaaacgataa
    30361 gataactatc agaaatacat tgaaggtcga gggggatttt cttgaatata agaaaatgca
    30421 gactagtatc gacctcccac aagaattaac tattcccgag catatcttga tcaatggaaa
    30481 tcaaattgat gccaaagata tcttgataac cggaaatcga gtcacgctaa atctgacaga
    30541 ttattttatt gctggagata cgttaataat cgaattggag acaactttgc aggaagtaat
    30601 tcctgaaaaa gtactcacta tgcattttga ataccttgaa aacgggaatt tgattgagca
    30661 atcgaatgaa ataaacctaa agatcgcaaa gctgaaggag atagatatcc atgtttatta
    30721 taaagataaa gacagtcaga ttgatattgc tgaaatgaaa acaatcactg ggaaaatagg
    30781 agagaagtat aaagaaactc ctattgatat tgaagggtat gtttttgact cggattcagc
    30841 gaatacagaa ggcatcttct ccgaaaatac agaggatatc tatttttatt acagaaaagg
    30901 caaactttat ctctcaactg ctcctcaata tgtcaatttt ggaaaacata aaatatccag
    30961 tagaccatta agtgaattcg gacagttttc aggtgggttg aaaattatag atgaacgggc
    31021 ttttggaagt tggaaattac aattgaaaca agagaaagtt cttacaaatg gagattttga
    31081 gcttccagaa gctctttcct ttgttacctc tgaaaataca acggttatag ggacatccgc
    31141 tgttacgatt ttcgaaagtg atcaaaaggg tgaaagcgat ttgtcctctc ttttagattc
    31201 tacagctcat cgtggaatca gaataaatat tcctgtagaa aaccaaagaa tcggaacctt
    31261 tgaggggaaa ctatcttgga tacttgcaga tgtcccagga aattaacagg aagagaagaa
    31321 tataacaaaa ttattgagtt tcaagaaggg cacaggtacc ataggctctt gtgtcccaca
    31381 gagacaagat tttgttatag tcttctctta catatgatta aaggagcgat tttcttgaga
    31441 ccaaaacaac aattatttat aacactccta gttattttag gggcactttt taacaatata
    31501 tcagtgtcag ctagtgcatt taatttttca gtgacgccga taacttcaga gaatcaaatc
    31561 gacaagagaa aaacttactt cgatcttcaa cttgatccgg atcaggaagt agaagtaaaa
    31621 gcggaattga gaaatgatac agaaaaagaa gtgaaaatcg atatttctgt gaatagcgca
    31681 accaccaatt caaatgtgat ggttgaatac ggaaaaaacg agattgaaaa agacatgagc
    31741 ctgatctttg atctggtaga ttatgtgagc tatccacaga tagtgacgct aaaacctaaa
    31801 agtgtccaaa ccgttgcttt tcatgtcagg atgccgaatg agcgatttga tggtgtattg
    31861 gctggtggga tcacattcca agaaatccag acggaaaagg accaaacaga aactaaggat
    31921 caaagcttat cgattgagaa tgaatacacc tatattattg ctttgttgat gcaacagaca
    31981 ctgaacgaag ttgctccgaa ccttactctt catgaagtta aaccagatca aatcaatgca
    32041 agaaatgtca tcttagcaaa cgttcaaaat gatcaaaaaa cctatatcaa tcaagtagtt
    32101 attgaaacaa aaattacaaa aaaaggacat tctgaagttt tatatcaaga ggaaaaagaa
    32161 ggattgcaga ttgcgccgaa tacaaatttt tcttttccaa ctgctttaaa tggtcaaccg
    32221 ctaaccccag gtgaatatca ccttacaatg actgttttag gaaatgaaaa tgaaaatgga
    32281 aaattttcga gaaaaaaagg aaatactacg atcaactata ccaatcaatg ggtatttgaa
    32341 aaagatttta caatagacgg aaaagtagcc aaggaattga acacgacgga tgttacgatt
    32401 aaaaaagaca ataattggat ttatatctta gtagcttcac ttttcttatt gtttatttta
    32461 ttatgcatac ttttgtttgt tttgagaaaa aaagaagaga aagaaaagta aggttaagat
    32521 aacaaatagt aaatttttat tattgtagga tggttgggct ctttttataa caatataaaa
    32581 tataccattt tattaataaa aatgcatact agtaaatgat ataattctaa taacaggttt
    32641 gatcgcgaga aaggccaaat aaaacgctct ccaaaatgtt aaaaaaaaga caggacgatg
    32701 tatattatac aaacaagaat cgctgacaac agtgactcgg atccaggaaa tcagttttat
    32761 ccccagctag ttggtgaatg catggaaagt aatatacgta gaaagagctg atgactaatg
    32821 aattatgagt tttttttaag caaagaagat cacagaagtt attcattact taaatattta
    32881 gaagcaagct caaatttatc agagtcaata tcgaatgttc aagaagagtt gtcgctatcg
    32941 acatttctct tgaaaaaaac gatcgataag ctgaaacatg atttacaaaa gttcgatcta
    33001 gagaaaaatt tgcgagtaac cgtcagtgaa ttggatatat gtctggaaat taatggaaaa
    33061 tgttctagca aagctctgtt atctcgttat ataacggatt ctttatctat gaaaatggta
    33121 ttggctttct ttcaggaaaa atatatctca gtagaaaatt ttgctaaaca gcatcacgtg
    33181 agttattctg tggcttataa agtattacaa agactaaaaa gaaatctaaa aaaatatcaa
    33241 attttttttg aaaagagaaa gtt
//
LOCUS       DAFLWQ010000030        29128 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.031, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000030 DAFLWQ010000000
VERSION     DAFLWQ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29128
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.031"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            356..694
                     /locus_tag="L1V16_001327"
     CDS             356..694
                     /locus_tag="L1V16_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275676.1"
                     /translation="MFDSIKNLVSGMTPDMKTLVQVVLYFLAFVFSLKPGFTAMKFFG
                     DAKWGDGLKYVGAIIAIFIIPVITTVMLYTMGTKTGNDLNQKANIISALIPVVGIYLV
                     SKFPKNELLG"
     gene            804..1025
                     /locus_tag="L1V16_001328"
     CDS             804..1025
                     /locus_tag="L1V16_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275677.1"
                     /translation="MVFDREKMLAHANEVLMSSLKGTELAKIMNMNVNQFYDYRNGSK
                     KIEKARLETLIKFEKAYVYMLDKQKRTID"
     gene            1045..3201
                     /locus_tag="L1V16_001329"
     CDS             1045..3201
                     /locus_tag="L1V16_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275678.1"
                     /translation="MAKFKDITESINYVAETVPVVALSLKPQLLEVYKKEEKEAKAKK
                     AKAKVWKEFDALLTKDLPKKNYMVIEDVQKLNSEGVIDEDDAILDSEKYVVLLKSSLN
                     YVADLPEKFKEKLLAGVRFMDSSGQLLVIPDDPNVFESEVEEATDFYSAVEQLEVATN
                     GLERIAETFNSSEEVEFEAVAENVPDEKEALFVDDNKPTEAENQEVSIEETQIQTETY
                     QQPKIDEKPESQSDKENYVYEAEKITSESDVPKNLDADFLEKNFEQIIADKFQPVVLD
                     EINDPVDLNEEMLSIPELKPLLFLAKESMNARISIANNKINSELNKTKEQLILKGKQM
                     LADELLRIEEATSLNGQNQFTNTLSVAKESYEAEASKIDDLVMEKSNIIRKDYDMAKQ
                     AYLDAELKKLEQRYDAEHLPEVKQQEDEYRKATEESLDQQYQEAIESIKNDALKQSQE
                     AKEVVVERIINSLKPEIEKSLTDVQEKTLEIVEKTKSENEAEFHDTKEKTTDVVVKYF
                     ANKEEVEKQVANNTKELETKLVEQQKTIEEYKDRMKEVKDLAEGYKLNSEKLAEQSEA
                     LREDLSRSRSDLAQMAEKTKSLAVATENQSSSKRDFTSKKMATIISVAAMACGTILGS
                     SYFISHNNQQAQAQTQTSISRVENSIGTNTNSASTNSSYEATPTTEFKVGKDVVISID
                     GKTTKAEVISIDGEKAVVKTPDGNQYKIQAHLSDNN"
     gene            3213..3446
                     /locus_tag="L1V16_001330"
     CDS             3213..3446
                     /locus_tag="L1V16_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1275679.1"
                     /translation="MREEKIVYPVIQNNQENMTSSQHLQEAQLVYQVNELPQTNETMS
                     KSISLIGLLIVAIVITVGVYRKLNVKGSISDGR"
     gene            3436..4302
                     /locus_tag="L1V16_001331"
     CDS             3436..4302
                     /locus_tag="L1V16_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275680.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVEWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLKFIFVPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNSARVSMGKKKPFRGTEILKVKQDGTIVYRDGSVALMFNLDGATSLTAFP
                     EEVMAQESKSIQYQNTRDRSLAEIKITSSQPQNTERQTRNMKIQKRNARSNKAVFDII
                     DQQERFVSEYIDGVKTTVIQYLILKSQSKMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSDIYALK"
     gene            4317..6287
                     /locus_tag="L1V16_001332"
     CDS             4317..6287
                     /locus_tag="L1V16_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275681.1"
                     /translation="MEIMGRSQLLNFKKKRKTKKEQKTRNSKVVNNTFVSDLTSLVGY
                     QFTPSYIRTGKRWGTIVKLVNTYGMNRNYGFGWMVKAIPEVRVEGVKAYLIEADKPVS
                     QKDQQEIMHENVGGSTNSYENNLEGKNSDAEISKTVMRIMDLNTASLLDSMANKIIDW
                     KLEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSYGGDQRDLFDRLLSEPIGNVYE
                     YTSMSSDFAGNDHAIRKGLDDANGWAIGTMSTSYASGVAFMALDDSFTSKVLVASHKN
                     ATIKGYDEKISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGRTFVAKPSLNS
                     VIEKVNLAEEGLNSLELFGNQKDIGDLYRRNLDKLTQIFYLLAGRTLDSATRVLLKKE
                     LGNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEVDRI
                     IVLKDTLRTALDSFSRMFNQRTTLKEIGKSDKLQFYYNLGDLRAETNVMEAQFLNTFD
                     FITSQAKKDDIVMIHGFDKLSIETVGLIKKRLTMLEEDGIRLAFLFDTIGSGEDNEYK
                     EDIETADIFNTDGKIYQSFESDFNYTIIGKMTSGELMKYEKKVAPARKGEDDQKLSVD
                     LRQYLTTGRSNKFQIRRPVDLTNNFVIGEFIL"
     gene            6454..6648
                     /locus_tag="L1V16_001333"
     CDS             6454..6648
                     /locus_tag="L1V16_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275682.1"
                     /translation="MKPNIKILDRIFLGRDTEVILIQHEEGFEVSIGIQKLQKPHYCN
                     QLYKNFTDEEKARVFFKTIS"
     gene            6682..7017
                     /locus_tag="L1V16_001334"
     CDS             6682..7017
                     /locus_tag="L1V16_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275683.1"
                     /translation="MKQYLNEWKAIEGSLVTQRIKELPDCLEKDHLFQIREMLKKEQF
                     DPDQFLVVEYPTIGVYCCNHINDGKYFIIQEYGGQLTPFYTTWEMSEEGINNFPCESI
                     EDSISHTEC"
     gene            complement(7274..8857)
                     /locus_tag="L1V16_001335"
     CDS             complement(7274..8857)
                     /locus_tag="L1V16_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275684.1"
                     /translation="MFILDDEIKKVKNPRIIPLLEEVRSSFYQGNYRSAIAVNYSALI
                     LDLIDKLSDLANIYEDNTSKKILEDIARLRKSDPNSPKWEMELLEKAYSSTELIDSYE
                     YEDLKYIKDQRNYSAHPVVTYNGNTWELRDITKETCQDVIRKSYEIIFLKNPILGKKV
                     TIEIIQYASRIHAMSVTPEEFHSALKNSYLNKLSEKAKENLCKTAFKFVFQLSYGNEE
                     ADRDRESTFRLLNALIFDNKEFYLNILKKEIAKYRFTAESREEINKSLGENQQITYTK
                     GFFLLTFIATHPELQHDFSDETIQNLQISINDFKPKQQVLTEIEYYYRLRSLAVLGNN
                     NEELQNHLNSLVDPILQQKMRVSSLPSSTLETIYNQYLYFGEKEMFIDFMIEHLTDAS
                     SFRLADKDMEVLPWIYNKLNQEQFNKLLYNLNGNNQFYKNSNFPPFISNLLDFYNQKF
                     QVNLRKHYSGLLYPNAVTMDQGFQLKDKELKKLYELAESKSDMYLDIIDNIINKSEDY
                     LRKEINSEKELLNYVHKIK"
     gene            8979..9563
                     /locus_tag="L1V16_001336"
     CDS             8979..9563
                     /locus_tag="L1V16_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275685.1"
                     /translation="MDLKQSFYIWLYPDNPMSIMADIFVVSILLYLFYLIFFHNLIGY
                     MILDWKGMFDIERKPFANNQTYTVFESGDWEENEVDVIHEIGLALSGIQDADVLVSMT
                     TDTGYNAYEVFYLMYFIWRDGQEIINGRAEKTINSNTEISFCMGEGEMIVYKDGSANI
                     KTAFGDIETSIKELREYVQNPYNFQYLAGRINLV"
     gene            9574..9819
                     /locus_tag="L1V16_001337"
     CDS             9574..9819
                     /locus_tag="L1V16_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275686.1"
                     /translation="MKKIINQPTNHLIIEGVIFVTMYFTVGNGISNTIIQKNPQYLLF
                     SLYAWIVQMVWVSILMLLFYWIVRVILLLLNKRKKDR"
     gene            9825..10547
                     /locus_tag="L1V16_001338"
     CDS             9825..10547
                     /locus_tag="L1V16_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275687.1"
                     /translation="MKSTKLKVVLLSTAALITLTACGTTNSANNNKDTKSSSTMVTKN
                     STTSASTTMSSMTENNAEKYQKYEDINKGQKPDEVYNNFINTVKNDENYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIKEGFSYAPTLMHDITINKPAYEYYAVAVDITDGV
                     PEWVQNIPGLADENNQYHTPTVAVVTPKKVNGTLYWDVMGMTTNTTDEMIESTTKYYM
                     DLGAYKLYQQSEPVMDDQSKVK"
     gene            10678..11421
                     /locus_tag="L1V16_001339"
     CDS             10678..11421
                     /locus_tag="L1V16_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275688.1"
                     /translation="MKEISANEAHIPQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKATSIRELRSEVEKIRLGLTSEEIAKLKGNNSFVIEKEKEKHLLYRELKIEEYYEI
                     DLPEKLRIIDQRSEEKWKTEIYPSLNDYKTSGKPMYNYTGFLTYTQYKYAFRKLKGIK
                     QAEIALYEMKKVDRLKLIQDLVQNTWNQAIVELEKENGKILTNKYLIVNEIEELIGLF
                     SCEKGEVFLKSSPTYSILDSPYQFIQARR"
     gene            11427..11792
                     /locus_tag="L1V16_001340"
     CDS             11427..11792
                     /locus_tag="L1V16_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275689.1"
                     /translation="MSSLKDDYIQAKQEYEKIQMLKSEKVELFLTQKLAEDHIANLDA
                     KTLEEYDRQFNQIHHNIILLVEQAKRRFEKAEYDLLDQGIVCLDKGLRRYYGAELKKQ
                     NVDRNALKHEILELIMQRI"
     gene            11808..12338
                     /locus_tag="L1V16_001341"
     CDS             11808..12338
                     /locus_tag="L1V16_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275690.1"
                     /translation="MSQNISAVKQLIEEDLETTVQRLAERIHFANYQTISNWSSRNRN
                     PEEIPMKFFYRIGKEYGVDPIKIFEKTMIYYYHGTPNEVLEHLLEEAKEKSSILELSQ
                     NDKVIQVKCVDPTGKIIVGFDIERKSKIDFITQLKKINNLDILTLRPDHEQLFMSFKK
                     QLKEIQKRYNKVFPNA"
     gene            12500..12808
                     /locus_tag="L1V16_001342"
     CDS             12500..12808
                     /locus_tag="L1V16_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275691.1"
                     /translation="MWNNRLKTGLLLIVISCAMMIGMRIQREQSYFEVSANNVIERCH
                     YGQHFWTGEVRENIDREYVQRIVWDAYSIKDYPKSLTSRLFYSEKDNQKLSDLMMKKV
                     "
     gene            12804..13223
                     /locus_tag="L1V16_001343"
                     /pseudo
     CDS             12804..13223
                     /locus_tag="L1V16_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352869.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            13360..14160
                     /locus_tag="L1V16_001344"
     CDS             13360..14160
                     /locus_tag="L1V16_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275692.1"
                     /translation="MSEDLRELKLRKKQYDQYFSGLLNKHIEEGLDHDFGKDEYCLYC
                     ERYNEKMSEYLQLKKEIQKLEKKVHAWKYKDSMSGYVESQNKPRKKKQAYVLKMVNGE
                     ELIVLAYSEEEVRELVETPVRKKVETINEIDDSQYNSIYIETSHGGYKKLATFLRSSK
                     VGIISKKDISAVTDSFCTLSVPKAYFQYDSKRFERLEKFCRPYTVLKTKKFNKTKRVS
                     IQLPTGQISLGEKDYLIKVGKELIIKVPEHLFKENFEIRETLVWKEEK"
     gene            14197..14379
                     /locus_tag="L1V16_001345"
     CDS             14197..14379
                     /locus_tag="L1V16_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275693.1"
                     /translation="MAVNKILQVLIIDEFGGGEWFDVQSIDFEEEVVVIENIYGEVYS
                     YSLEGENIEDLRLIGE"
     gene            14490..14807
                     /locus_tag="L1V16_001346"
     CDS             14490..14807
                     /locus_tag="L1V16_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275694.1"
                     /translation="MKREEYKQRLNELLEEDETLTHGSPDEILYMIDNMVIFGGYELG
                     NRSVDHNILEFDDVSWEEILDWGILAVPETKTYISDTMVPFFEELDYKRLPKNENHIL
                     GGN"
     gene            14810..15042
                     /locus_tag="L1V16_001347"
                     /pseudo
     CDS             14810..15042
                     /locus_tag="L1V16_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321015.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(15157..15636)
                     /locus_tag="L1V16_001348"
     CDS             complement(15157..15636)
                     /locus_tag="L1V16_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275695.1"
                     /translation="MTDKTSDLPKLAPKTSRVKSKKDGKTKNAVKKKSVKETSSLLLD
                     IPMSSFDDNTDETSVKIATHVGMNNQNDSFYNLLNSLRELEDKKNQVIASKAPDLTTD
                     LDAEIIQIKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISLQKKSDD"
     gene            15756..17093
                     /locus_tag="L1V16_001349"
     CDS             15756..17093
                     /locus_tag="L1V16_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HBN1275696.1"
                     /translation="MLMVQFTGIAMSVITINPQVIHADGIATYDAQFNCTTEGSGSGT
                     DSDGNDTGSGAVTGDVAKNIEDIYKYMNGEYGLSGASIAGILGNWKQESGIDPRAVEG
                     YYGDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVDWSKKNNGGSWWTTEAQLDFMF
                     KGDGGFVGILKDYALNASDDVVENAVTFHKNWEISADSESAVIAVRGENAKEIWKYMK
                     SKGMDGAKDESKINKISGGSSTGDGSNNSSSSASGTVEDACATTDDANSGSGSIGKEG
                     KINGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFNGIYQGQCTELTWAYMS
                     QLYDGNQPTTGNGGYVWESYKSAGAKITNKPIVGYGFSASDGWLWAVGDAGHTGVVIA
                     VFEDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGKAKFEIEK"
     gene            17116..17643
                     /locus_tag="L1V16_001350"
     CDS             17116..17643
                     /locus_tag="L1V16_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275697.1"
                     /translation="MNSKVKDTIIISLLSGMLLALLVGILFFNKQNQDIEAEKHSVHI
                     EDKLTFFKEVKPNEVDGLRKDLENDIQEMLNGSVQNKFADQSGEEFLRKLFIVTGKPP
                     ITDKSSEKEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            17630..18193
                     /locus_tag="L1V16_001351"
     CDS             17630..18193
                     /locus_tag="L1V16_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275698.1"
                     /translation="MQNHEITTAKKAIGILSIIVILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLEDLDSYVRAE"
     gene            18615..19352
                     /locus_tag="L1V16_001352"
     CDS             18615..19352
                     /locus_tag="L1V16_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275699.1"
                     /translation="MADHKLEKLLEETWNPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENKGTWDFWATLANKELSDKSDTGIRNFFESNRDDYMYANNQN
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISELGGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVKITNKLDYGSWADIALEKYIYSTLKEFIENRMDIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            complement(19369..19785)
                     /locus_tag="L1V16_001353"
     CDS             complement(19369..19785)
                     /locus_tag="L1V16_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275700.1"
                     /translation="MNKKRKLSVLITLVSILTILSVILSLKIFNQINTSSNAKDGIVV
                     ENTSNSKETGTTTKKYKSAEITTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKNDELYSFVK"
     gene            20177..21424
                     /locus_tag="L1V16_001354"
     CDS             20177..21424
                     /locus_tag="L1V16_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBN1275701.1"
                     /translation="MNMKRNSLGMVLLASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNISK
                     DTLTVKEADGEVVSQTVQKDKPDPIENTEQENKKSETTKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTEADTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSKPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKPMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            21692..24082
                     /locus_tag="L1V16_001355"
     CDS             21692..24082
                     /locus_tag="L1V16_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HBN1275702.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMMLSTLIMPFSAIRAEADVTKPT
                     SAKFIETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     EFSYTATNTIKKGKVKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGVFKQEGITVKDDGQTFEYTATNTLKKGLVKVHKVDQDGKPL
                     ANAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGITVK
                     DDGQTFEYTATNNLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDSNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDGQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            24131..25966
                     /locus_tag="L1V16_001356"
     CDS             24131..25966
                     /locus_tag="L1V16_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBN1275703.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANKTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKSVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            26035..26898
                     /locus_tag="L1V16_001357"
     CDS             26035..26898
                     /locus_tag="L1V16_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1275704.1"
                     /translation="MSMKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNS
                     YKEKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNGNLQKDKLGEL
                     VGEILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKY
                     FTDLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVG
                     DNSHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIAVIVIIKKI
                     VAKRRGMKNEE"
     gene            26888..27997
                     /locus_tag="L1V16_001358"
     CDS             26888..27997
                     /locus_tag="L1V16_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1275705.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDKGVDNTQETDGGSFDIREAEGKVNPY
                     TGDVFSKNQTKDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLP
                     LSGKGHQTVIAGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQ
                     NSTLTDIPDLDMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDS
                     ESVSDKTETVTSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTG
                     ITNKHQKMLLVIWTVIGALASLKVLILLIKEFRKA"
     gene            28336..>29128
                     /locus_tag="L1V16_001359"
     CDS             28336..>29128
                     /locus_tag="L1V16_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275706.1"
                     /translation="MVGVSKTALDSLAKLFSSRFDGAEFVEYLSQNESGKTLIETMKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLIGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYANDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKE"
BASE COUNT        10909 a         4002 c         5643 g         8574 t
ORIGIN      
        1 aactgaagat gtcaaggaaa atttctattt atgcaaaaaa attattttaa attgtctata
       61 aatgaattaa atatttactg ttcaaagttg tataattaaa aagggcttat gctggtaaag
      121 aacagaatta ttatctaaac aaaaacttga taaaccagca tttttagcca ataaaaaaag
      181 tgaaataatt taatggaaaa tctcttttaa tcatcgaaaa tttatgttat tatgataaca
      241 taaagatgta aatatcgaga cgtctttttc ttagttagat cattgacaag tgaacaaata
      301 agatttgtcg atgatataat taacttatta aaaatattaa aaaggaggtt tttatatgtt
      361 cgattctatt aaaaatttgg ttagcggaat gacgcctgat atgaaaactt tagtacaagt
      421 tgttttgtat ttcttggcat tcgttttttc gttgaaacca ggattcactg caatgaaatt
      481 ttttggtgat gcaaaatggg gagatggatt aaaatatgtt ggggcgatta ttgcaatctt
      541 tattattcct gtaattacaa ccgttatgct ttacacaatg ggtactaaaa caggtaatga
      601 tttgaaccaa aaagctaata tcatatcagc acttattcca gttgttggta tctatctagt
      661 ttcaaaattt ccaaaaaatg aactgttagg ttaaaagtga attgaacaaa tttggataat
      721 atgccgattt gttcaattta ctttttacca aaaaactacg ctccaagcgt agtttagaag
      781 tgagggaaga aagtaaatgt aagatggttt ttgatagaga aaaaatgtta gctcacgcca
      841 acgaagtatt aatgagcagt ctgaaaggta ccgaactggc aaagataatg aatatgaatg
      901 ttaaccagtt ctatgattat cgaaatggga gtaaaaagat tgaaaaagcc agacttgaaa
      961 cgcttattaa attcgaaaaa gcatatgtat atatgctaga taaacagaaa agaactattg
     1021 actgaaaaaa ggagttttac aataatggca aaattcaaag atattaccga atctattaat
     1081 tatgtggcag aaacagttcc tgtagttgca ctctctttga agccacaatt actcgaagtg
     1141 tacaaaaaag aagaaaaaga agcgaaggca aaaaaagcta aagcaaaggt atggaaagaa
     1201 ttcgatgcgt tgctgaccaa agatttacca aagaaaaatt atatggtaat tgaagatgta
     1261 caaaagctca acagtgaggg agttatagat gaggatgatg ctattctcga ttctgagaag
     1321 tatgtcgttc tattgaagtc aagtttgaat tatgtagctg atctaccaga aaaatttaaa
     1381 gagaagctat tagcaggtgt ccgttttatg gatagtagtg gtcaattatt agttattccg
     1441 gatgatccta atgtgtttga atcagaagtt gaagaagcta cagacttcta tagcgcagta
     1501 gagcaattag aagtagctac taatggatta gaacgaattg ctgagacctt caactcttct
     1561 gaagaagttg aatttgaagc cgtagcagaa aatgtaccag atgaaaaaga agctcttttt
     1621 gtggatgata acaaaccaac cgaagcagaa aaccaagaag taagcataga agaaacacaa
     1681 atacaaacag aaacctacca acaaccaaaa attgatgaaa aacccgaatc ccaaagtgac
     1741 aaagaaaatt atgtttatga agctgaaaaa atcacatctg aaagtgatgt accgaaaaac
     1801 ttagatgctg attttttaga aaaaaatttt gaacagatca ttgctgacaa atttcaacct
     1861 gtagttttag atgagattaa tgaccctgtc gatttaaacg aggagatgct atccatacct
     1921 gagttgaaac cattgctgtt tttagctaaa gagagtatga acgctcgcat ctctattgct
     1981 aataataaaa tcaacagtga attaaataag acgaaggagc aattgatcct caaaggaaag
     2041 caaatgttag ctgatgagct tttgcggata gaggaagcaa cctcattaaa tggtcaaaat
     2101 cagtttacaa atacactatc ggttgctaaa gagagctacg aagcagaagc atctaaaatt
     2161 gatgatttag tgatggaaaa atccaatatc attcgtaaag attatgatat ggcgaaacag
     2221 gcttatttgg atgctgaact aaagaaacta gagcaacggt atgatgctga gcatttacca
     2281 gaagttaaac aacaagaaga tgaatataga aaagcaactg aagaaagtct tgatcaacag
     2341 taccaagaag caattgaatc tattaaaaac gatgcattga aacaaagcca agaagcaaaa
     2401 gaagttgtgg tggaacgaat tatcaattca ttgaaaccag aaattgaaaa atcattaaca
     2461 gacgtgcaag aaaaaacttt agagattgtc gaaaaaacaa agtcagaaaa tgaagctgag
     2521 ttccatgata caaaagagaa aacaacagat gtggttgtca aatattttgc gaacaaagaa
     2581 gaagttgaaa agcaggtagc taacaacacg aaagaattag aaacaaaact tgtagagcaa
     2641 caaaaaacta tcgaagaata taaagatcga atgaaagagg tcaaagattt agcagagggt
     2701 tataaattaa atagcgaaaa gttggcagaa caaagtgaag ctttaagaga agacttatct
     2761 cgttcccgaa gtgatctagc tcaaatggca gaaaaaacga aatcattagc agttgctaca
     2821 gaaaatcaat caagttcaaa acgtgatttt acaagtaaaa agatggctac tatcatttct
     2881 gtcgctgcaa tggcttgcgg aacgatcttg ggatcgtcct actttattag tcataataat
     2941 caacaagcac aggctcaaac tcaaacatct atttcgagag tggaaaattc gattgggaca
     3001 aatacgaact ctgcttcaac aaatagtagc tatgaagcaa caccaactac agagttcaaa
     3061 gttgggaaag atgttgtcat cagtattgat gggaaaacaa ctaaggctga agtgatttct
     3121 attgatggag aaaaagcagt tgtgaaaact ccagacggaa atcagtacaa aattcaagct
     3181 cacttatctg ataataacta aggagggcta ttatgcgaga agaaaaaata gtttatccag
     3241 taattcaaaa caatcaagaa aacatgacct cttctcagca cttacaggaa gcacagctcg
     3301 tgtatcaggt aaatgaacta ccacaaacga acgagacaat gagcaagtca atatctttaa
     3361 ttggcttgct tattgttgca atagtgataa ctgtaggtgt ttaccgtaag ttgaacgtga
     3421 aaggaagtat ttctgatggc agataactca aactatggat ttaaacataa cttacatcaa
     3481 aaaccttctg aaacaattgt cagagttgaa tggcttgaaa agcatgtcaa tagcacctat
     3541 tctgttacag caaaaagatt aattgtatca gctatagttg ttgcagtcgt tgttcttgga
     3601 tcaattgttt acttagtttc tgatacgatt aaactgaaat ttatttttgt tccaacgtta
     3661 ttaatgataa ttggatttct tattctaatt agccagtata tgtttattga tccatctagt
     3721 ggttcattga tttctggttc tattagactg ttcaaatcag tagttaattc agcaagagta
     3781 tctatgggga aaaagaaacc atttcgaggc acagagattt taaaagtgaa acaagatgga
     3841 acaatcgtat atcgagatgg gagtgtagca ttaatgttca atctagatgg ggctacatca
     3901 ctaaccgctt ttccagaaga agttatggct caggaatcga aatcaataca atatcaaaat
     3961 accagagatc gttccttagc tgaaatcaaa atcacttcat ctcaacctca gaatacggaa
     4021 agacaaactc gaaatatgaa aatacaaaaa cgaaatgcaa ggagtaacaa agcagtcttt
     4081 gacataatag atcagcaaga acgatttgta tcagaatata ttgatggtgt gaaaacaaca
     4141 gtaatccaat atcttatctt gaaatctcaa tctaagatgg tattggatga aggtgtggaa
     4201 cgtttagaaa actatacgag tagaggactt tattatagtg tcactcagtt gtcagctaaa
     4261 caaacaaaag aaatattatc tgatatttat gcactgaaat agaggtgaga gattaaatgg
     4321 aaattatggg tagatcacaa ctattaaatt tcaaaaaaaa gagaaaaact aaaaaagaac
     4381 aaaaaactag aaattcaaag gtagtgaata atacctttgt tagtgattta acatctttag
     4441 ttggttatca atttacacca tcttacatta ggacaggtaa gcggtgggga acaattgtga
     4501 aattagtgaa tacttatgga atgaatagaa attatggatt tggttggatg gttaaagcta
     4561 ttcctgaagt gagagtagaa ggggtaaaag cctatctaat tgaagcagat aagccagtgt
     4621 cacaaaaaga tcaacaagaa ataatgcacg agaatgttgg gggatcaacg aatagttatg
     4681 aaaataattt agaaggaaaa aattcagatg ctgaaattag caaaactgtt atgcggatta
     4741 tggatttgaa tacagcatct ttactagaca gcatggcaaa taaaattatt gattggaagc
     4801 tagaaatcct attagtatcc gattctccta ataaaatcag cgaacagcta attaaactcc
     4861 aacggttgta tgatgaaaaa atgtatggat taaagcttat gtcatatgga ggagatcaac
     4921 gtgatctgtt tgatagactt ttaagtgaac caatcgggaa tgtctatgag tatacgtcta
     4981 tgagttcgga ttttgcagga aatgatcatg caattcgcaa aggtttagat gatgcgaatg
     5041 gatgggctat cggcactatg tctactagct acgcaagtgg tgtagctttt atggcactgg
     5101 atgattcttt tacaagtaaa gttttagtgg catcacacaa aaacgctaca attaaaggct
     5161 atgatgaaaa aatctcagca tcatcacttt gggggcaatt gattgctaat aatgcaatgg
     5221 caaatcataa acgaactttt catattgtct taaataaatt tgattacttt ggtgatccaa
     5281 ctggtagaac atttgttgcc aaaccttcgt taaacagtgt aatagaaaag gttaatttgg
     5341 ctgaagaagg tcttaactct ttggagcttt ttggtaatca aaaggacatt ggtgatttat
     5401 atagacggaa tctcgataaa ctaactcaga ttttttattt gttagcaggc agaacattag
     5461 attctgcaac tagagtttta ttgaaaaaag aattaggtaa cttttatata agtcagaaac
     5521 tttgggatat taattatgaa gaacgttcaa aacttttggt gaacagtagt gatacaatgc
     5581 cagttcttgg ggattttatt agctatttga ctaatgctga aacaaaagcc aaaaaatctg
     5641 gtactgaaaa agaagtcgat cgtattattg tattaaaaga cacattgaga acagcattag
     5701 acagcttctc taggatgttt aatcaaagaa cgacactgaa agaaatcggt aaaagtgaca
     5761 aattacagtt ttactataac ttaggtgatc taagagcaga aaccaatgtt atggaagctc
     5821 aatttttaaa tacctttgat ttcatcacat cacaagcaaa aaaagatgat attgttatga
     5881 ttcacggctt cgataagtta tctattgaaa ccgttgggct aattaaaaaa agattaacaa
     5941 tgcttgaaga agatggaatt cgtcttgcct ttctatttga tacaatcggt tcaggagaag
     6001 acaatgaata caaagaagat attgaaacag ctgatatatt caatacagat ggaaaaattt
     6061 accaaagttt tgaaagtgat tttaattaca ctatcattgg aaagatgacc agtggagagt
     6121 taatgaagta tgaaaaaaaa gttgctcctg ctagaaaagg agaagatgat caaaaacttt
     6181 ctgttgattt gagacagtat ttgacaacag gaagaagtaa taaatttcag atcaggagac
     6241 cagtggatct gactaataat tttgttattg gagagtttat tctttaagtt ttatctttga
     6301 ttttgagtgt ataaggaaag gataagaaaa aacatgtata tttgagacta aaaacagtct
     6361 tagagaacat ggtacgtttt gtgaaaagag aactatagaa atttcataaa gtgaaacctt
     6421 actgagtgaa ataattatag tggaggttaa ataatgaaac caaacataaa aattttagat
     6481 cgaatatttc taggtagaga cacagaagta atcctaattc aacatgaaga aggatttgaa
     6541 gttagtatag gtattcagaa acttcaaaaa cctcattatt gtaatcagtt gtataaaaac
     6601 tttactgatg aagaaaaagc gagagttttt tttaaaacaa tttcctagga aaaatagtta
     6661 acataaaagg aatgaattgt tatgaaacaa tatttaaatg aatggaaagc gatagagggg
     6721 tcattagtaa cgcaaagaat aaaggaatta cctgattgct tagagaagga tcatttgttt
     6781 caaatacgag aaatgttgaa aaaagaacag tttgatccag accaattttt agtagtcgag
     6841 tatccaacta ttggagtgta ctgttgtaac catatcaatg atggaaaata ttttattatt
     6901 caggagtatg gaggacagtt aactcctttc tatactacat gggaaatgag tgaagaagga
     6961 atcaataatt ttccatgtga aagcatcgaa gattcaattt cacacaccga atgttaattg
     7021 attataacta taaaaaagga ttgaacatta tgttcaatcc ttttttcaat gaaatgtttt
     7081 ccgccatttc attgtttggt gcgatttcta ttttattata tcaaaataaa gagagattct
     7141 aaagaaagaa gagggaaata tataaatcaa gcgacagtat atttattatt aaatgctatt
     7201 gtgagaatat aactaattag tttaatttga aagtaaatat acgctataaa agtgcatctt
     7261 gtgttataaa aaattatttt attttgtgaa cataatttaa caattctttc tcggaattga
     7321 tttcttttct taaatagtct tcagacttat taataatatt atctattatg tctagataca
     7381 tatcactttt cgattcagct aattcataca gtttttttaa ttctttatcc tttaattgaa
     7441 aaccctgatc catagtcact gcatttggat atagaagccc actataatgt ttacgtaaat
     7501 tcacttggaa tttctgatta taaaagtcta acagattaga aataaaaggc ggaaaattac
     7561 tgtttttgta aaattgatta tttccattta ggttgtatag taatttgtta aattgctcct
     7621 gatttaattt attgtaaatc catggtaata cttccatatc cttatctgct aacctgaatg
     7681 aactagcatc ggtaagatgt tcgatcataa aatctatgaa catctctttt tcaccaaaat
     7741 ataaatattg attatatatt gtttctaatg ttgaagatgg tagcgaagaa actctcattt
     7801 tttgctggag tataggatca actagactat ttaagtgatt ttgtaattct tcattgttgt
     7861 ttcctagaac tgcaagggaa cgtaaacggt agtaatattc tatttctgtt agtacttgtt
     7921 gtttcggttt aaaatcattt attgatattt gtaaattttg aattgtctcg tctgaaaaat
     7981 catgttgtaa ttctggatgg gtagctataa aagtaagtaa aaagaaccct tttgtatacg
     8041 tgatctgttg attttcacca agtgatttat taatttcctc tcttgattca gctgtgaacc
     8101 tatactttgc aatttctttt tttagaatat ttaaatagaa ttctttatta tcaaaaatta
     8161 gggcattaag tagtctgaaa gtactttccc tatctctatc tgcttcctca tttccataag
     8221 ataattgaaa aacaaactta aaggctgtct tacataggtt ttctttggct ttttcgctta
     8281 gtttatttag atagctattt tttagtgcag agtgaaattc ttcaggtgta acagacatag
     8341 catgtatgcg acttgcatat tgtataattt cgatcgttac tttttttcct aatattggat
     8401 tttttaggaa tataatttca taggacttcc gtataacatc ctgacaagtt tcttttgtta
     8461 tatctcttaa ttcccaagta ttaccgttgt aagtgactac aggatgagct gaataatttc
     8521 tttgatcctt aatatatttt aaatcctcat attcatagct atcaattagc tcagttgaac
     8581 tataagcttt ttctagtagt tccatttccc attttggaga gtttggatca ctttttctta
     8641 gtctagctat atcttctaaa attttcttag aagtattatc ctcgtaaata tttgctaaat
     8701 cagataattt atcaattaaa tctaaaataa gcgcactgta attgacagct attgcagaac
     8761 gataatttcc ctgataaaaa ctacttctaa cttcttctaa taatggaata attctaggat
     8821 ttttaacttt ttttatttca tcatctaata taaacatata aatctccttt ttttatttgt
     8881 atgacaagtt taccataaaa aaaaattaaa aagcgagaca tatttatgtt gttgtgttat
     8941 cataataaca taaatatgta gagtgagatg atgaaaaaat ggatttgaaa caatcgtttt
     9001 acatctggtt atatcctgat aatcctatgt caataatggc tgatattttt gtagttagca
     9061 tcttattgta tttattttat ctaattttct ttcacaattt aatcgggtac atgattcttg
     9121 attggaaagg aatgttcgat atagaaagaa aaccatttgc taacaatcaa acctataccg
     9181 tcttcgaaag tggagattgg gaagaaaatg aagttgatgt gatccatgaa attggattag
     9241 ctttatcagg aatacaagat gctgatgttt tggtatcaat gacaacggat actggataca
     9301 acgcttatga ggtattttat cttatgtatt ttatatggcg tgatggtcaa gaaattatca
     9361 atggtcgtgc tgaaaaaaca atcaattcta atactgaaat ttctttttgt atgggtgaag
     9421 gggaaatgat tgtatataaa gatgggtcag caaacattaa aacagccttt ggtgatattg
     9481 aaacaagtat taaggaactt agggaatatg tgcagaaccc atataatttt caatatttag
     9541 caggaagaat aaatttagtt taggagtaaa aatatgaaaa aaattataaa tcaaccaaca
     9601 aatcacttga taattgaagg tgttattttc gtaacaatgt attttactgt aggaaatggc
     9661 atctcaaata caatcattca aaaaaatcca caatacctat tatttagtct ttatgcttgg
     9721 attgtacaaa tggtttgggt ttccatattg atgctgttgt tttattggat agtacgggtt
     9781 attcttttat tgttaaacaa aagaaaaaag gataggtgaa taaaatgaaa tcaactaaat
     9841 tgaaggttgt attgttatcg acagcagcat taataaccct tacagcatgt ggtacaacta
     9901 atagtgctaa taataacaaa gacacaaagt ctagtagtac gatggttact aaaaacagca
     9961 ctacatcggc atcaacaaca atgtcttcaa tgactgaaaa taatgctgaa aagtatcaaa
    10021 aatacgaaga cattaataaa ggtcaaaagc cggatgaagt ttataacaac tttattaata
    10081 cagtaaaaaa tgatgaaaat tatgggaatg atccattgca aaataaaaat ctgactatcg
    10141 ttctttacaa acctgattgt ccagattgtc aaaaagcaga atcaaaaatc atgcaagaaa
    10201 taaaagaagg atttagttat gctccaacat taatgcatga tattaccata aataaaccag
    10261 cttacgagta ttacgcagtt gctgtagata ttactgatgg tgtacctgag tgggtacaaa
    10321 acattcctgg tctggctgat gagaacaatc aatatcatac gccaacagtt gcagtagtaa
    10381 caccaaagaa agttaacggc acactatact gggatgtaat gggaatgaca acaaatacaa
    10441 ctgatgaaat gattgaaagt acaactaaat attatatgga tttgggagca tataaattat
    10501 atcaacaatc agagcctgtt atggacgatc aatccaaagt taaatagatc tttagggcgt
    10561 aagccctatt tttttaaaat taagtgataa caaataaatg atttctgaaa caaacgttct
    10621 tactcaacta ctcgaaacac acaagctaat taactagatt ataaaggaga atgcgtaatg
    10681 aaagaaatca gtgcaaatga agctcatatt ccgcaaaaga atcaggttgg tatatataag
    10741 gtgcttcatg gtgaaggaat ttataaaata cagttactta ccggttacaa taatggtgca
    10801 aatgggaagt ggttaaaggc aacaagtatt cgtgaactta gaagtgaagt agaaaaaatt
    10861 aggcttggtc tcacaagtga agaaatagct aaactgaagg gaaataattc ttttgtaatt
    10921 gaaaaagaaa aggaaaaaca tctactttat cgtgagctga aaattgaaga atactatgaa
    10981 attgatttac ctgaaaaatt aagaattatt gatcaacgtt cagaagaaaa atggaaaact
    11041 gaaatatatc caagcttaaa tgactacaag acatcaggaa agcccatgta taactacaca
    11101 ggctttttaa cctacacaca atacaaatat gcctttcgca aattaaaagg cattaaacaa
    11161 gctgaaattg ccctgtatga gatgaaaaaa gtggatagat tgaaattgat tcaagattta
    11221 gtgcaaaata catggaatca agcgattgtc gagctagaaa aagaaaatgg gaaaatttta
    11281 actaataaat atctgatcgt aaatgaaatt gaagaattaa ttggtttatt ttcatgtgaa
    11341 aaaggtgaag tcttcttgaa gtcatcacca acctattcaa ttttggacag tccgtatcag
    11401 tttatacagg caaggagatg agttagatgt ctagcttgaa agatgactat atccaagcaa
    11461 aacaagagta tgaaaaaata cagatgttga aatctgagaa agtcgaatta tttttaacac
    11521 aaaaattagc agaggatcat attgctaact tagatgctaa aactttagag gaatatgatc
    11581 ggcagtttaa tcagatacat cacaatatca ttttgcttgt tgagcaggca aagcgaaggt
    11641 ttgaaaaagc ggaatatgat ctattagatc aaggaattgt atgcttggat aagggattgc
    11701 gaagatatta tggtgcagag ttaaaaaagc aaaatgtaga tagaaatgca ctaaaacatg
    11761 aaatcttaga attgataatg caacgaattt gaagggatag aaagcaaatg tcacaaaaca
    11821 ttagtgctgt aaaacaatta atagaagaag atttagagac cacagttcag agattagcgg
    11881 aacgaatcca ttttgcaaat tatcaaacca tctctaactg gtcaagcagg aacagaaatc
    11941 cggaagaaat tccaatgaaa tttttttatc gaatcggaaa agaatatggt gttgatccga
    12001 taaaaatttt cgagaagacc atgatttatt actatcatgg aacacctaac gaagtgttag
    12061 aacatctttt ggaagaggca aaagaaaaat catcaatatt agagctatcg caaaatgaca
    12121 aagttattca agtgaaatgc gttgatccaa caggaaagat tattgtcggt tttgatattg
    12181 aaagaaaatc caaaatagat tttattacac aattaaaaaa gataaataat ttagatattc
    12241 taacgcttag accagatcat gaacagttgt ttatgagttt taaaaaacaa ttgaaagaaa
    12301 tacaaaaaag atataacaag gtgtttccta atgcgtgaaa agctcaaaga aatcagagtt
    12361 ttttggataa ttaacaaaga atgtatcatc ttatatactc ttggatttct tagcatgatc
    12421 ttgttttggt ggttatattt aaaacagtaa ttggagaggg tcaagaggat ttttatcaag
    12481 ataaggatgt ggaaactgca tgtggaataa tagattaaaa acaggattgt tattaatagt
    12541 tatttcctgc gctatgatga ttggtatgag gatacaaagg gaacaatcct attttgaagt
    12601 ttctgctaac aatgtaatag aaagatgcca ttatggtcaa catttttgga ctggggaagt
    12661 cagagaaaat atagatcgtg aatatgttca aagaattgtt tgggatgcat attctatcaa
    12721 agattatcct aaaagtttaa cgagtagatt attttacagt gaaaaagata atcaaaaact
    12781 ctcagatttg atgatgaaaa aagtatgact attattacga aagagaaaca gagtgctata
    12841 ttcgagggga aaaagcctac aacaaaagtg actattgggg tgacaaggcg aagcgattaa
    12901 ctgcaaattt tagagtgtat gaatcagagt ttataaactt gacctttctt aatagtgttt
    12961 ttattgatta tgtaattact acgaaacgca ttggaagtta ttcaagtacc tacgcatcct
    13021 tagttccaat gttaaactcg atgagccgtt tcttaaaaga aagagaaaag aaagagctac
    13081 agtatatcaa agaaatcatg ccggattttg aaatgcacga atggcaaatt gctttatcag
    13141 attggaaatt ggcgaataag gttcgtagaa taacaccttt tcaagccaag cgctttttga
    13201 gagctatgaa atttgtgcaa taaaaaaagc caccagacaa gttgatggag actaacacaa
    13261 ttaccaacag ttgtaattgt gttagcttac aaattaatta tggtgtttag tcaatcccaa
    13321 attgtgaaat ggcaccaata attggaaagg aaaaatgaaa tgtctgaaga tttacgagag
    13381 ctgaagttac gaaagaagca gtatgatcag tatttttccg gtttgttgaa taaacatatt
    13441 gaagaaggac ttgatcatga ttttggaaaa gatgaatatt gtttatattg cgaacgttac
    13501 aatgaaaaaa tgtctgaata tctacagctg aaaaaagaga tacagaaatt agagaaaaaa
    13561 gtacatgctt ggaagtataa agattccatg tctggttatg ttgaatctca aaataagcca
    13621 agaaaaaaga agcaagcgta tgttctaaag atggtaaatg gggaagagtt aattgtatta
    13681 gcgtacagtg aagaagaggt tcgagaactc gttgaaacac ctgtcaggaa aaaggttgaa
    13741 acaataaatg agatagacga cagccaatac aatagcatct atattgaaac aagtcatggt
    13801 ggatataaga aattagcaac tttccttaga agttctaaag ttgggataat ttctaaaaaa
    13861 gacataagtg ctgttaccga tagtttttgt actttatctg ttcctaaagc ttatttccaa
    13921 tacgatagta aaagatttga acgcttagag aaattctgta gaccgtatac tgtattgaaa
    13981 actaaaaaat ttaataaaac taaaagagtt tctatacagt taccgactgg tcaaatctca
    14041 ttaggtgaaa aagactatct gataaaagta ggaaaagagt taattataaa agtaccggaa
    14101 cacttattta aagaaaattt tgagatacgt gaaaccttgg tatggaaaga agaaaaatag
    14161 tttggaagac atagaatggt ataaggggaa attgaaatgg cagtaaataa aatattgcag
    14221 gtactaatca tagacgaatt tggcggagga gaatggtttg atgtgcagtc catagacttt
    14281 gaagaagaag tcgtagttat agaaaatatt tacggcgaag tatattcata ttcgcttgaa
    14341 ggtgagaata ttgaggattt acggttgatt ggtgagtaga aaaaaacaga aatatcaaaa
    14401 tggagataaa aattaatagc atgtaaagat agtcatgctt gggttaaaaa tgttaaaatt
    14461 caaaaaaatg agtcagaagg gataaaagta tgaaaagaga ggaatacaaa caaagattaa
    14521 acgaactgct tgaagaggac gaaacattaa ctcatggttc gcctgatgaa attctataca
    14581 tgattgataa tatggtgatc tttggtggat atgaacttgg taataggtca gttgatcata
    14641 atattttaga atttgatgat gtatcatggg aagaaattct tgattgggga attttggcgg
    14701 tacctgaaac taaaacctat attagtgaca ctatggttcc tttttttgag gaattggatt
    14761 ataaaagact tcccaaaaat gaaaatcata tactgggagg aaactaacaa tgttaagtga
    14821 cttatttatt ttactgatct atctaggtgt aagtgaaatt attgcgtatt ttttgtttgt
    14881 cattgctaat tatggtattt ccagtgcaat cgttcaaatg tttagattac cagtaagtga
    14941 actaaaaaaa tgatgagatt atcagcatat cttttaatgt ttttgaatgt ggtcacgtta
    15001 atctttgtag taatcggtgt gactttcgat ttaatggaat agtgggaaat ctataatgga
    15061 aaaaagagac acgaatgaac atattttttg aatcaatatt gttgatggtt tttgcgatca
    15121 gcgcttacca gaaatctaaa aaagagtaat gattgtttaa tcatcactct ttttttgtag
    15181 ggaaattgaa atatgtggag cttgtattgg tttagttagg attgcttggc tataaggagc
    15241 tagttcttta tcaaaaccat caaagtaggt tttcagtagc gatttaactg atcgctcatc
    15301 ttgtttgatt tggataattt cagcatccaa atcggttgtg agatcaggag cttttgatgc
    15361 gattacctga ttttttttat cttccaactc tcttaggctg tttaacaagt tgtaaaaaga
    15421 atcattttga ttgttcattc caacgtgagt tgcaatttta acagaagttt cgtccgtatt
    15481 gtcatcaaaa gaactcattg gaatatcaag tagtaacgag gatgtttctt ttactgactt
    15541 tttctttaca gcattttttg tttttccatc ttttttgctc tttactcgag atgtttttgg
    15601 agctagttta ggtaaatcac ttgttttatc agtcatttat tagcttttcc tttctattaa
    15661 tttatgttat tatattatca taataacata aaaaagtaca ctttttgggg gcgtagttat
    15721 tgaaaaaatc taagagaaag attgccacat tgcttatgtt aatggtgcaa tttacaggga
    15781 ttgcaatgag tgtaatcaca ataaatccgc aagtgataca tgctgatggg atagctactt
    15841 atgatgcaca atttaactgt actactgaag gtagtgggtc aggaacagat agcgatggaa
    15901 acgatactgg aagtggcgct gtaacaggtg atgtagccaa aaatattgaa gatatttaca
    15961 aatacatgaa tggagaatat ggcttatcag gtgctagtat tgcaggtatt ttaggtaact
    16021 ggaaacaaga atcaggtatt gatcctcgag cagtagaagg gtattacgga gatggacaga
    16081 gagaagttga cttcatcaaa caatttactg atggtctgat gggtattggc tatggtcaat
    16141 ggacagctgg gcgacataca gcattagttg attggtctaa gaaaaataat ggcggttctt
    16201 ggtggactac agaagcccaa ttggacttta tgttcaaagg tgatggggga ttcgtaggaa
    16261 tattaaaaga ttatgcttta aatgcttctg atgatgtcgt agaaaatgca gtaacttttc
    16321 ataaaaactg ggaaatttca gctgattccg aatcagctgt aatagctgta cgtggtgaaa
    16381 atgcaaaaga aatctggaag tacatgaaaa gcaagggtat ggacggtgca aaagatgaaa
    16441 gtaagatcaa taaaatatcc ggaggttcaa gtaccggaga tggatcgaat aattcatcaa
    16501 gttcagcatc aggaacagta gaagatgcct gtgcaactac ggatgacgct aattctggtt
    16561 ctggatcaat tgggaaagaa ggaaaaatta acggtaaaaa aggtcaagta atagcgaata
    16621 tgacttatga agaagctttg aaaaaatatg ggaaagcgat cacgctacca aaattcaaag
    16681 aaccagattg gtcaacttca ccttttaacg gaatatatca aggtcagtgt acagagttga
    16741 cgtgggctta tatgagccaa ttatacgatg ggaatcaacc gactactgga aatggtggtt
    16801 atgtatggga aagctacaaa tcggcaggag caaaaataac gaacaaacca atcgtaggtt
    16861 atgggtttag tgcttcggat ggatggttat gggctgttgg agatgcaggg catactggtg
    16921 tagttatagc ggtgtttgaa gatggatcat ttctatgtgc taactttaat gttccaccaa
    16981 cccaagctcc aacaagggga gtttcggtaa cgttgattga tggagtggac ggatcagata
    17041 atgtgcattt ctttagcggt gtaggaaaag ctaaatttga aatcgaaaaa taaattggaa
    17101 tgaaggacga tatagatgaa tagtaaagtg aaagatacaa ttatcatttc tttgctttct
    17161 ggtatgttat tagcactgct tgttggaatc ctattcttca ataagcagaa tcaggacata
    17221 gaagctgaaa aacacagtgt gcatattgaa gataagctga cattctttaa agaggttaaa
    17281 ccaaatgagg tggatggatt acggaaagat ttagaaaatg atattcaaga aatgttgaat
    17341 ggatcagttc aaaataagtt tgcagatcaa tcaggtgaag aatttttgag aaaactattt
    17401 attgtaacag gtaaaccacc aattactgat aagagtagtg agaaagaaaa aatcgagtac
    17461 tataagcctt ttacttttaa gctaacaaac tttggaatta agacatctag tagtgggttg
    17521 tatgaagcat tgaccgattt tgaagttcaa tacaatggaa aaaaagtgta tgataccaca
    17581 ttaaccatca cactaaataa tgataagaaa gtgactgggg gtgcttttta tgcaaaatca
    17641 tgaaatcact actgctaaaa aggcgatcgg aatactttcc ataattgtga tcctttgttg
    17701 tgtggtacta tttcaaaaga aaaatgctta tgataataat gtcaaagaat tggaagacct
    17761 taaaagtaaa caaatcgaag tagtcaagaa taaccagaaa gtgaaagcta tgcaggaagc
    17821 tcaatacaaa gaattgggaa atgctgaaat taaggaacaa agtaggaaat tctttaattt
    17881 attttacaac tggaattcat gggaaaaata tacgaagaat atgaaggaaa tacaaaaaga
    17941 atttcctcag atagtaaagt ctagtcctgt tgatatttct ggcacgatgg taggcactgg
    18001 taatagtcca atatctagct atactgctga ttactataca acaaatcaaa aaggtaaaat
    18061 ggttgaattg attacacaga caagaaatac tccaacaaca gcaacaacaa caatttggcg
    18121 tggagtaaca agcataggag aaaatcaatt gttttatttg gaggatttag atagctatgt
    18181 aagagcagag taaaataaaa aaagagctaa cggtaccaac gttagctctt tgtgctgacg
    18241 atgataacaa aacctaccga aaaaggattg tttcatcaca aacacaaaca gaaaagaatt
    18301 gataaaaaac ccgaacctca gaatttttat taatcaattc atttagatta taataaattg
    18361 agctgaacat tacaatacgt atatgttgta aaacgtaaaa aaagtcaaaa gtaaatactt
    18421 tcttaaaaag tcaaataaaa ctattaaaga caatatatat ggtttatttg acataagaaa
    18481 atggtctaga tgataattgt aatatagaat tgtagactta aataaagcat aaaatacctt
    18541 ttatgataag gtatagctct taattttaag cagttttaga tataagattg aaagtaaagt
    18601 gggggagaat aataatggca gatcataaat tagaaaagtt attagaagaa acgtggaatc
    18661 caaaagaatt tagtgaattt tttatggaga attttgaaac tgacttagca gtgattgtta
    18721 aagatgctct tagagagcaa gggtatcctg aaactgcaaa ctatataaac attaatttta
    18781 ctttgtatac tgaaaataaa ggaacttggg atttttgggc tactttagca aataaggagt
    18841 taagtgataa atcagacaca ggaattcgta acttttttga atcaaacaga gatgattata
    18901 tgtatgctaa caatcaaaat aaattgaact ttagagtaga gtttgatgaa acacctgaag
    18961 aatttataga aagacaaccg cctaaagaaa atgtagcaaa ggtattggaa gatcgttgga
    19021 attcagatga aatagtttca acaattagcg aactaggcgg acaatatgaa ccgctagtag
    19081 aagcggttag agaagagcta agactgaata agtttcctga tgttcaaaat attgatgttt
    19141 ctcaaattga aataaacgtc aagatcacga ataaacttga ttatggtagt tgggcagata
    19201 tagcattaga aaaatacatc tactcaacgt taaaagagtt tatcgaaaat agaatggata
    19261 tcatgtatct acagcatcca cagtatttaa actttggtgt tgaaatagct acacctcttg
    19321 aagaatggaa aatggagcaa gggcttgact agcctttgct ccattttttt attttacaaa
    19381 tgaatacagt tcgtcgtttt taccaagaat gattgtttgc ccaactttga gattgtcagg
    19441 tgatccttca gcggtttgta aggagaacgt tccattgaac ttatcggata ccgttatagg
    19501 tagctttaat tctgatcctt cctcatcttt gagaattgct gtttttcgtt catcaaaata
    19561 aacagtcttt attaaataat ttttcgtagt gatctcagca gatttgtatt tttttgtagt
    19621 agtaccagtt tctttagaat tagaggtatt ttctacgact attccatctt tggcatttga
    19681 gcttgtgttt atttgattga atattttcag cgacaagata acgctaagaa tagtcaatat
    19741 agaaacaagt gtaattaata ctgataattt cctttttttg ttcatttttt cttaacatcc
    19801 ttttttgttt tgattagtta gatattcctt atctaacaag cctttttagg ctattaaatg
    19861 aagataaacc ccaaaaaata ttgcaattat gacagtgcaa tggtactatt attatacaat
    19921 aaattttgcg aaaggggtag gtctaaatcg caaacaaaaa gaaattgaac ctagacaaat
    19981 acaacttgta taccgcaagg gaagcaagtt tgattttggg taaaggtaga aattatgtta
    20041 caaacataat caactattat ccaaatcgtt tgcctaaagg ttcgttcaag aaagtgggtg
    20101 acaaaaccta tattataacg gaagaaggaa tagaagcatt gcgatcacaa acagaaaata
    20161 aaaacaaaaa gaaggaatga atatgaagag aaattcgctt ggtatggttt tattggcatc
    20221 agctgtactt gcggggttat cagtaccagt aacctcacat gctgatgaat ggactgcaaa
    20281 cacaccggat caaatccaaa ttacaacagg acaatcaagt tatgcgttca aaaaaggaga
    20341 tactatttgg tcaactgtag agaagcttaa aagcttaggt tacaagacta ctgttgctga
    20401 gtttgccgaa ttgaacaatg ttgatttggc aaaaggagaa caacggacta tcccgattgg
    20461 acgaactttc aacatcagta aagatacatt aacagttaag gaagcagatg gcgaagtagt
    20521 tagtcaaact gttcaaaaag ataaacctga tcctattgaa aatacggagc aagagaacaa
    20581 aaaatccgag actacaaaag aatcggaacc aacagcaaac acttctgata agacagaaac
    20641 aagtgcttca agtgttgatg gagcaagttc atctaataca aataattcta caagtgagaa
    20701 agaagcatca cagggaacaa gtgaaagtag cactacggaa gctgatactg gaacatcaac
    20761 aaataactca caatcaacat caaatgatgc aaatgaatca accagtacat cttctagtga
    20821 tcaatcacaa acaggttcga gtgatgaaac tgacagttct acttcaccaa gtaaacccga
    20881 acaaccaact aatgttgtgc taggcgttcc atttattagt caaggtaaca caatgctttg
    20941 cgaaggaaca tctttgctag aagcgttaca ttataaaggt gttgcaacaa atcaagattt
    21001 aatgactttt gttaaatcaa tgccactatc tcctgacaat aatccaaata atggtttttc
    21061 tggtgaatgg agacacaatg tggatggaac ttatcaaggt atgaatccgg ctcctgtagt
    21121 ttcatggggt gttgctaatg gcggaaatgt tgtagatatt tctggttcat cggtacaagg
    21181 attaaaagat gagattgtaa atggaaatcc tgtagtagcg tgggtaactt atgcctttga
    21241 acctgctcaa cataaaccaa tgttttgggg cgatgctatt tggaatcgac atgtagtagc
    21301 cgttgatgga tttaaagacg gtttttacca tgttgtcgat cctgtgtttg gggcaagttg
    21361 gattaatgca ggatcatttg aaacagcata taacgtatct caattagcgg tttcggtacg
    21421 ttaataaaag atatcgttta tatactaagt agttatatag tctttatttg tccttgctta
    21481 actacttaga aaacttgttg ctcatggtgg gtagaactaa aaggggtgat gctatgaata
    21541 ctagagcgtt gaaacagctt gctttcaacg aaaaaaatga ttaataggtg tggtgatttt
    21601 aacttaggaa tgggcgcgaa ggtcattacc acaccgacat atcgtggctc attttcttcg
    21661 cctaactggt ataaagaagg agtaacgaga gatgaagcat gaaaaaacga taattttaaa
    21721 atcaaaaata atttattgtt ttgcgacttt agtaatgatg ttatctacgc ttataatgcc
    21781 tttttcagca ataagagctg aagcagatgt cacaaaaccg acaagtgcaa aatttataga
    21841 aactggcgta aaaacagacg gttatattag ggttaatatg ccgaatcatc caaatgaatg
    21901 gatgatttca agtcaattta aagattctca tggaaatatt ggatattgta tggattcaga
    21961 attgccatcc ccaacaggaa gtggagccgg aagcttgaag tacaagggag ctggcagtga
    22021 tgagttctat cgtatgttta aaggtggttt tccatcaaaa acagcaaagg aactgggtgc
    22081 aggaaatgat acagaagcat ggtatgcaac acaattagtt tcatgggttt tagccggaaa
    22141 ctttaaagtt tcacagattg tatggtcaca tccaaaccat accgccgcag aaacagctcg
    22201 tgtaaaaaaa gcatttgaaa aaatttatga ctatgctaag aatggaaaag atacgcccaa
    22261 cactgagttt tctatcacag cttctaagac agctgacgaa ggaaaatatc acactttcac
    22321 atataaaaca gcatcaaata agactggtaa tgcgaagctc acttttacat cagcaaaacc
    22381 agctggtatg aagatttatg atgcagatgg taaagaaatt actaacaaca ctgtgaaatt
    22441 aaattcaagt tttactatta aagtacctgt gactacacca agtggtactt tgtcatttaa
    22501 aggtactgct aatgttagca caaccaatcc ttttactttt gatggacgag gtgtgtatca
    22561 agatgccgta gttatgatca ctacttcaga aacaaaggac tctaaatctt tgagtgctaa
    22621 atggacaaga gctgttggtc aggtaacagt taagaaagtt gatcaagatg gaaatgcttt
    22681 aaaaggagcg gagtttactc taactgacaa taacaatgct aaatctgtta agacaaccgg
    22741 agatgatggg ttagctacgt ttgatttgca acaaggctta acatacagct tagaagaaac
    22801 aaaagttcct gaaggttatc aaggttcatt taaaaaggat ggtattactg ttaataccga
    22861 tggacaagaa tttagttaca ctgctacgaa cacaattaaa aaaggtaaag taaaagttaa
    22921 aaaggttgac caagatggaa aaccattagc taatgctgaa tttaccttga cggatgattc
    22981 atcccaaaca caagcagaaa aaacagatga aaacggactt gcaagcttcg atattgtagc
    23041 aaacaagacc tacagccttg aagagaccgg agtaccaact ggttatacag gcgtattcaa
    23101 gcaagaagga attaccgtta aagatgatgg acaaactttt gaatatacag ctacaaacac
    23161 tttgaaaaaa ggtttagtaa aagttcataa agtcgatcaa gatggaaaac ctttggcaaa
    23221 tgcagagttc actttaaccg atgaaaaagg tgcaacacaa gtagaaaaaa cagatgaaaa
    23281 tggacttgca agcttcaata ttgtagcaaa caagacgtat agcctagaag aaaccggagt
    23341 accagtaggt tacacaggtg catttaagca agagggtatc accgttaaag acgatgggca
    23401 aacttttgaa tatacagcta caaataattt gaaaaaaggt gtagtaaaag ttcataaagt
    23461 cgatcaagat ggaaaacctt tagcagatgc agaattcacc ttaacggatg aaaaaggtgt
    23521 aaaagaagtt aaaaagacgg atgcaactgg tctggctacg ttcaacatta ttgcgaacaa
    23581 aacttataac ttagaagaaa caaaagtacc aacaggttac acaggcgcat tcaaacaaga
    23641 aggaattacc gtcaaagatg atggacaagt ctttgaatat actgctaaaa acactttgaa
    23701 aaaaggtgtg atcaaagttc ataaagtgga tgatcaaggg aaagcattag caaacgcaga
    23761 attcactttg acagacgaca aaggtgtaaa agttgtacaa aaaacggaca gcaatggctt
    23821 ggcaacattt aatattgttg ccaacaaaac gtacaaaatc gaagaaacac aaaaccctaa
    23881 tggttataca gggaaatggt ctaaagaagg catcaccgtt gctgacgatg gacaaacctt
    23941 tgaatataca gtaattaatc accttgtacc tgaaacagta agaacaggcg gaatcggtac
    24001 atcagccttc cttcttgtat ttctaattgc aggattgagt atggtgctac tgtattatcg
    24061 agaacagcac aaagcaaaat aaaaaagtgt taatggaaaa gaagtaaata tgaaaaaaga
    24121 aggctgacgt atgaaatcaa aaaaaatttt ttcaaattta atgctatttg gtactttgct
    24181 aggagtggga ttgggcgcaa gctcaatctc ttctagcctt ggactagggg ggcaagtagc
    24241 atatgcacaa caaaactata attatcaagg aactggaacg attcatatcc ataaagtaac
    24301 aaatactaat ggggatggga accctgtctc agatattgat aacaaaggga aagaaatagc
    24361 tttaccaaat ggtgtaaaac ctcttgaagg cgttgagttc tcttatgtga aacttactaa
    24421 agatgaagct aaatccttgg gatggacgga tagtgatact acaaaaggtc aacatattga
    24481 tgatgctaaa gcacgattat tactaaacaa aaaatacagt gaagtaagta gaatgaagac
    24541 tgattcacaa gggaatatag acatacctat acaagtaaat acagacgatt taacagataa
    24601 cttgtatttg attgttgaaa caggaacagt caaaggtgta gttgaagaag cgtatcctat
    24661 gattgttaac gtacctgaac taaacggatc agatgatcaa tactttaatt atgatgtaca
    24721 tgtctatcct aaaaactatt tccaattaaa ctcagcagag cttgataaaa aagacgaaga
    24781 tggaaaggct cttgccggaa ctgtttttga attgcgaaaa gatgatggat ctgatcaggt
    24841 tgttggaact tataaaacag acagcacagg taaattaact gtagatggtt tggaattagg
    24901 tgactattat ttcctagaaa ccgatttggg aacagatgct aataaaacaa cctatttact
    24961 agatggtaaa aaattcaaat ttagcgttaa acgtggggag actgctaaag tagttcttga
    25021 tgttaccaac tacaaacgac ctgtaattac taaggtaatt gataaagaaa ccgttgatac
    25081 tggcgaagat gttcaatata cattgaaacc atcaattcct ggtaatattg gtaattacga
    25141 aaaatatgtt gtcaaagatg ttctaggtgc agagttaact tatgattcat cagaagtgat
    25201 cgaaggaatg actttagata ctgattacag tatcgaacgt gacggacaaa cgacaaacta
    25261 tgtctttact gaatcaggta tggataagct tcagaaacaa tttgatgcag gggatcgctt
    25321 ctttacaatt ttgatgaacg ctcatactaa tagtaaagct aaaatggata caccacttaa
    25381 gaatgatgtt tcaacgatct acaacaatgg atatgaaccc gaagacgaaa caccagttga
    25441 tcacgcttat acaatcattg gtgatcacca attcattaaa acagatggag atacaagcaa
    25501 agcattgagt ggagcaaaat ttgtagtgaa gaacaaaatt gatccgaata aagttactta
    25561 cctaaaacaa gatccaacaa cgaaatctgt tacttggatt gcagataaat ctaaagctac
    25621 tgaattcgtt tccggatcag atggtaagtt ccaaattgaa ggcttgcaat atacctatga
    25681 tgtagatttt gataaacaag gtaatccaac aatcacagat aaaaaaatca atgattatgc
    25741 tcttgaagaa gttgttgctc cttcaggata tacaccaact agaaatgatg ttccatttgt
    25801 ggtatcgaat gatgatgctt ctagcgaagt aacagacatc aagaacctta aaacacctga
    25861 aacagttcgt acaggtggaa ttggaacagt agtatttcta gtggttgcag gtgtggcagg
    25921 aacagggcta tatgttgtct acaaacgaga acaacacaaa gcttaatgaa ataaaattcc
    25981 ctagagtgtt tttggctcta gggtttcttt ttaaaaagtg tgtgaaaagt aggtatgagc
    26041 atgaaaaaga agaatatcaa gttgatcatc ttaaaaattg ggatgttgct atgtttagga
    26101 gtaggtctat atcctgtaat tactcaggct tatacctact accaaactca acaaacacta
    26161 aactcctata aggaaaaata tgatgaagct tctgaaaagg agaatgaaga agtcttcaag
    26221 agatattcag aagttaatag gaaacgaaaa gacacagaac aaacctcagt cacgattcct
    26281 gaagataata acaatattcc gtcaaatgga aatcttcaga aggataaatt aggtgaatta
    26341 gtgggtgaaa ttcttatacc aaagattaat gtggatttgc caatttatga tggtgtaaac
    26401 gatttccaac tatcagcagg agcaggaata ttaaccggaa ctgattatcc aactggtggg
    26461 attggaaacc attctgttat atcagctcat tcaggcattc ctaataaaaa atattttaca
    26521 gatttagagt tgctcaaact tggtgataaa ttttttattg atatttcagg gaaaaaactt
    26581 gcttatcaag tagatcggat aaaaacaatt ctaccaaccg aatttgagga tttgcttcct
    26641 gtggcaggaa aagattatgt aacacttatg acatgtacac ctgttggaga taattctcat
    26701 aggttactcg ttagaggggt tagcatacct taccaaaaaa gtattgttga gaaagaaaag
    26761 aagaaagaag atttaaaggt aaaggcgcag atgaactggt atcctatcgt agttgtaggg
    26821 gttttattaa taatagctgt gatagtcatt attaaaaaaa tagtagcaaa gagacgagga
    26881 atgaaaaatg aagaataaaa tactactttt tttgactctt atttgcactt tggttttaac
    26941 aatttatcct gcaaatcagc tctatcatca attcaaaaca aaagagaatg tggcggaaat
    27001 ccaagagaaa attgagaaaa aacaaactcc ttcaaaagag gaagtggcaa aaaaagtcga
    27061 acaaataaaa tcgaacagcg gtaaccaagg attagacaat actcagaaaa cagataaagg
    27121 agtagacaat actcaggaaa cagacggtgg atcatttgat attcgtgaag ctgaaggaaa
    27181 ggtcaatcca tacacaggag atgttttttc aaaaaatcaa acgaaagatt ttgaaccatc
    27241 tacctattca ggagcggttg gttatgtcta tattccaaaa ataaatgtgc tagagctttt
    27301 gtttctaggc gcttcacagg agcatttata tagaggtgtg gcacaaatga gtgctactag
    27361 tctaccttta tcaggtaaag gtcatcaaac agtaatagca ggtcatcgtg gcggttatac
    27421 gtcaccacaa tttctttatg ttgatcaatt agtagccgga gaccacattt atatagatta
    27481 tcttggtgaa aaagcagttt atacggtttt ccgaacagac gttattagaa attacggtca
    27541 gaattcaaca ctgactgata ttcctgattt agatatgtta acactttata cttgtcatcc
    27601 atatcctcag aactacgatc gtttattagt tagaagtcta agagatgaaa aagcaaaata
    27661 catcacgcca caagtaacag ttggcaatac cgcatacgct gatgccattg atagcgagtc
    27721 cgtttcagat aagacagaaa ctgttacatc ttctaatgat ttatttgaag atgttgatcg
    27781 tgccaacaag gaattagatg gaaataatga tcttaatatt ccggaacaag gtagcgtaga
    27841 gatgcaagac agaacgtttg ctgaaaaggc aagttcaata tttacaggaa ttaccaataa
    27901 acatcagaaa atgcttttag tcatttggac tgtaatagga gcattagcaa gtctaaaggt
    27961 tcttattctt ttaatcaaag agtttcgaaa agcataatga agattataaa aattgataga
    28021 gtacagtaaa aagggattga tactattatt gatctctttt ttattttgaa tagagctaga
    28081 ttcactttta aataaaatca aaactgatct taattctaaa gaaaaagtca agaaaaaaat
    28141 acaataaatt tttttatcag aatatttatc agaatattat tagaaaagat aaactcaaaa
    28201 gcttaattta atagggttat tggttgtatt tagaaataat gtatggaaaa gctataaagc
    28261 aatagataag atgtagaaaa tcttatttgt gaatgaaaaa caagtcatcg taaaatatta
    28321 ataggaggtg tagtaatggt gggagtatca aaaacagctt tagactcatt agctaaacta
    28381 tttagtagca ggtttgatgg tgcagaattt gttgaatatc taagccaaaa cgaaagtgga
    28441 aaaactctga tcgaaacaat gaaaaaagac tatttgaatg aaaatgactt tccgacatgg
    28501 acgaatattg aagatgctac atgggatgta gtatgtacga tatattctcc ttgggtaacg
    28561 attgctgatt ttgttttaga taaaattgga ggggatacat accctgatgc caaatctctt
    28621 gctacaagtg actttaaaac gttctatggt tatctaatag gtctaatagg caatggaata
    28681 gatttgaaag ttacgccaaa acaaacacct gaagaaattg aaaaagaaaa aggagaggtt
    28741 caaatggctt atgcaaatga cagagaaaaa gtaaaattat tggaaggtaa attatctgaa
    28801 gaagaacttg gaaaaatggt gcaagaaatc aatgaagaca gcaactattt tcctgaattg
    28861 aaggtatatc aaaatgacga agatttcttt aatgaaatgt ttagtaatag tccatgggaa
    28921 gcagtaagta aaacaaattt aggagaatgg aactttcaag atgatctagt tgcatttagc
    28981 aatgatgggt atttacgatc atattcagaa agtgagtata gagctgaatt aaaaacgtat
    29041 gaaacggata ttctgatgag ctatttaaat ctattagaga gtggtcaggg agagttaaga
    29101 gataaagttg aagaactatt aaaagaag
//
LOCUS       DAFLWQ010000031        29049 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.032, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000031 DAFLWQ010000000
VERSION     DAFLWQ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29049
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.032"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(82..534)
                     /locus_tag="L1V16_001360"
     CDS             complement(82..534)
                     /locus_tag="L1V16_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBN1275707.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(547..957)
                     /locus_tag="L1V16_001361"
     CDS             complement(547..957)
                     /locus_tag="L1V16_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1275708.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            1232..1444
                     /locus_tag="L1V16_001362"
     CDS             1232..1444
                     /locus_tag="L1V16_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1275709.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            1447..1659
                     /locus_tag="L1V16_001363"
     CDS             1447..1659
                     /locus_tag="L1V16_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275710.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            1799..1954
                     /locus_tag="L1V16_001364"
     CDS             1799..1954
                     /locus_tag="L1V16_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275711.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGKKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(1951..2175)
                     /locus_tag="L1V16_001365"
     CDS             complement(1951..2175)
                     /locus_tag="L1V16_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBN1275712.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            2253..2441
                     /locus_tag="L1V16_001366"
     CDS             2253..2441
                     /locus_tag="L1V16_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275713.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            2438..2611
                     /locus_tag="L1V16_001367"
     CDS             2438..2611
                     /locus_tag="L1V16_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275714.1"
                     /translation="MKKTDTLFIGFILGLLVIVAHQSIIGGSLFAALMVLINLLDSKE
                     RSNYGTRRSAKNR"
     gene            2767..3102
                     /locus_tag="L1V16_001368"
     CDS             2767..3102
                     /locus_tag="L1V16_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275715.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            3335..4276
                     /locus_tag="L1V16_001369"
     CDS             3335..4276
                     /locus_tag="L1V16_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HBN1275716.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            4278..5168
                     /locus_tag="L1V16_001370"
     CDS             4278..5168
                     /locus_tag="L1V16_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBN1275717.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            5211..6011
                     /locus_tag="L1V16_001371"
     CDS             5211..6011
                     /locus_tag="L1V16_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBN1275718.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADDIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            6026..6877
                     /locus_tag="L1V16_001372"
     CDS             6026..6877
                     /locus_tag="L1V16_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1275719.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            7078..7539
                     /locus_tag="L1V16_001373"
     CDS             7078..7539
                     /locus_tag="L1V16_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1275720.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            7565..8017
                     /locus_tag="L1V16_001374"
     CDS             7565..8017
                     /locus_tag="L1V16_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275721.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            8123..8317
                     /locus_tag="L1V16_001375"
     CDS             8123..8317
                     /locus_tag="L1V16_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275722.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNEFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            8348..8641
                     /locus_tag="L1V16_001376"
     CDS             8348..8641
                     /locus_tag="L1V16_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275723.1"
                     /translation="MKLKDGFYSSGHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVVRLVDMEVIKS"
     gene            8671..9111
                     /locus_tag="L1V16_001377"
     CDS             8671..9111
                     /locus_tag="L1V16_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBN1275724.1"
                     /translation="MSVIPQLEGEEAIVNILENIDIKQTRKNARRLLKRYRNLERLVG
                     PVKIDFSVMTVTKNLKFTIDSQNEEIIEAISTRDSVIEALTRLSRIHFQVLYYSYCFP
                     NKMSMYQIGEKLGYSDRTIERMKAVALVEFAEAYKSGELISRTK"
     gene            9186..9653
                     /locus_tag="L1V16_001378"
     CDS             9186..9653
                     /locus_tag="L1V16_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HBN1275725.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQHR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            10400..10630
                     /locus_tag="L1V16_001379"
     CDS             10400..10630
                     /locus_tag="L1V16_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275726.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMGREAE
                     PCEIDACKLVYCGHGFYDEPNIQNNINKNLRD"
     gene            10789..11622
                     /locus_tag="L1V16_001380"
     CDS             10789..11622
                     /locus_tag="L1V16_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HBN1275727.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELISNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            11615..13030
                     /locus_tag="L1V16_001381"
     CDS             11615..13030
                     /locus_tag="L1V16_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBN1275728.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPESMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTKVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            13042..14571
                     /locus_tag="L1V16_001382"
     CDS             13042..14571
                     /locus_tag="L1V16_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBN1275729.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKAPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            14489..15541
                     /locus_tag="L1V16_001383"
     CDS             14489..15541
                     /locus_tag="L1V16_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBN1275730.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            15543..15860
                     /locus_tag="L1V16_001384"
     CDS             15543..15860
                     /locus_tag="L1V16_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275731.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            15987..16610
                     /locus_tag="L1V16_001385"
     CDS             15987..16610
                     /locus_tag="L1V16_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HBN1275732.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            16625..17515
                     /locus_tag="L1V16_001386"
     CDS             16625..17515
                     /locus_tag="L1V16_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HBN1275733.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            17538..17753
                     /locus_tag="L1V16_001387"
     CDS             17538..17753
                     /locus_tag="L1V16_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275734.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            17765..18106
                     /locus_tag="L1V16_001388"
     CDS             17765..18106
                     /locus_tag="L1V16_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275735.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            18106..18477
                     /locus_tag="L1V16_001389"
     CDS             18106..18477
                     /locus_tag="L1V16_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275736.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            18470..18865
                     /locus_tag="L1V16_001390"
     CDS             18470..18865
                     /locus_tag="L1V16_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBN1275737.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGEVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            18867..19244
                     /locus_tag="L1V16_001391"
     CDS             18867..19244
                     /locus_tag="L1V16_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275738.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNNPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            19245..19853
                     /locus_tag="L1V16_001392"
     CDS             19245..19853
                     /locus_tag="L1V16_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1275739.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            19853..20194
                     /locus_tag="L1V16_001393"
     CDS             19853..20194
                     /locus_tag="L1V16_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275740.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            20436..23225
                     /locus_tag="L1V16_001394"
     CDS             20436..23225
                     /locus_tag="L1V16_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBN1275741.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANPFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            23215..23955
                     /locus_tag="L1V16_001395"
     CDS             23215..23955
                     /locus_tag="L1V16_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1275742.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            23952..26714
                     /locus_tag="L1V16_001396"
     CDS             23952..26714
                     /locus_tag="L1V16_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1275743.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCGIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWRIYDILCNNGFTK
                     QSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLF
                     NAAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGFKACTDPRQAAYAFERNYE
                     RPAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYS
                     GYLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIIN
                     WARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISS
                     IVIPPK"
     gene            26727..27635
                     /locus_tag="L1V16_001397"
     CDS             26727..27635
                     /locus_tag="L1V16_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBN1275744.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            27635..28255
                     /locus_tag="L1V16_001398"
     CDS             27635..28255
                     /locus_tag="L1V16_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275745.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            28259..28708
                     /locus_tag="L1V16_001399"
     CDS             28259..28708
                     /locus_tag="L1V16_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275746.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKAKLDGLANITFEKVGTV"
     gene            28708..>29049
                     /locus_tag="L1V16_001400"
     CDS             28708..>29049
                     /locus_tag="L1V16_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275747.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYR"
BASE COUNT        10430 a         4187 c         6022 g         8410 t
ORIGIN      
        1 ctcatttctt tgatataatt attgtagagt ttactcagaa atgaggaaag agtccatgtg
       61 aaagcatggg cttttttatt tttaatgttg taatactaaa tgttcaagat tatgaggaag
      121 ccctaaatat tcaataattt ggaactgact catatcagat aaatcttgtt catctattgt
      181 tctagttaac atttcaattg caaacatatt agcttcagct tctataccat aaatcataca
      241 actaaggttg tttgctctaa aagctgctgt gcaaatacct ttatggagtc taacgtgggc
      301 tatttcatgc cataatacaa atcttttcat agaaggtgat aggttttgat taattaatat
      361 cacataacat cttttattgt gtatcgtttg tcctaatgtt ttattcccta aatcagtttc
      421 aattaaatct atatcagaat atttgattat tttatatgga ttaatcgcat cagatccaaa
      481 ctctacaaat aatttttcta tttcttctaa tatccagtat ttgtttaaat gcataccaaa
      541 gcccacctat tgacgatatt ttttaggagt gaattttttc tttgctttaa ctttggttaa
      601 ggcaagtgca agttgaatgg catcgtataa tttttcctta tcttcatcgt ctaaaggttc
      661 accataataa tttgtttcag catctgaatt caagccttca agtaattttt cagcttgtaa
      721 agcaatatct tgtttatctt tttctgttaa atcataataa tggcgtttat cagtacgtcc
      781 taaaagataa tcagttgata cattaaagta atctgcaact ttttgtattt tatctccaga
      841 tggagtactt ttattccatc tagacatgct tccatttccg aaatttaact ttctttcaag
      901 ttctgccaac gtcattgaac gttcttttaa taagattttt atacggtcta atagcatagg
      961 atatgcattc ctttcaaaat accgacaaaa aaagtatttt tctgcaaatt atctatttac
     1021 aaatagagaa tttgcagtta tactagtttt gtaagcaaga tatttacggc atacaaagac
     1081 taaaagcaat aaactaatag tctccccaga catcagtaag ctcgcttttt gtgcgctgta
     1141 ttttgtatgc ttacataata gcatatttgc agtttttgtc aaacttatta gacaaaaata
     1201 ttagaaaata ttcgataagg gggtatgaag catgacttta aaacagcaag tattaattgc
     1261 tttagtaaag aaaggttgga gtcaaagaga gttagctcga cgaatgggta tatcaattac
     1321 ttatttacga gatatcttca tcgaaaaaag aaaacctaag gaacgtttaa aacaaatcga
     1381 agaacttttg gatatcaagt tagaagtaga ttctaatgat cagccatcag aacaggaggc
     1441 gtaaaaatgg tacaacgttt gagcaaagcg gagtttaaag agaaatataa gtattctgaa
     1501 agtacttatc aaagaagaat gaaggaattt aaaaaatcac gttttagtga ggggtataac
     1561 gcagttactt ccaaagaaat aacaattgat gtcgatttat atgaacagtt tagaacatgg
     1621 cgttctaaaa atcgatttag agttagagct gtttgttaat agctaaaaaa tctaaattca
     1681 ccacttctga aaagaggagt tgctgctctc ctttcaagtt tgccaaagtc cacgtttttt
     1741 cattttggca actcctcttc ttggaggtgg tgacggcgag agacgaagga gggatgacat
     1801 gaaggaagaa tcaaaaatag ggattttgaa tgagaacaat tacacaagat taattattga
     1861 aacagaagaa gggaaaaaag tagcagaagt tacattgacc gatgcaactc ctgctgacgg
     1921 ttatcgtatt cgattaactc ctaaatatga ttaacctttt ggtgggtgtg gatcgtttcc
     1981 gtgactatca cggctttgaa tttttccatc tctgccatga ataaatagct cagatccttg
     2041 atttttagaa atctctctag cgatttttac tgcttctgat tttgtattag tatgtgcagt
     2101 cgctttagaa tttccagcac ctttgacatt ccaaccacca ttggaattag gtacaacatg
     2161 ttgatttttt cccatagttt tcacctccat ttctatagaa atattttatc aaatagaaat
     2221 ggagaaattc aataaacgaa aggagaagtg atatggcata taccttgcaa caagaacatc
     2281 aaattctcgg tttgattaaa caacgcagga aacaattaca agatgaccgt gcagcgctta
     2341 gaaaagccga tgagctatca gataggcaag ctgaactaat tgcttctgaa cttgaggatt
     2401 tgagaatgct agaaataaaa aatagggaga ttagattatg aagaagacag acacactttt
     2461 tataggattc attttggggt tattagtgat tgtagcgcac caaagtatta tcgggggaag
     2521 cttgttcgca gcattgatgg ttttaatcaa tctgcttgat tcaaaagaaa ggagcaacta
     2581 tggcacgaga agaagcgcta aaaatcggta aagtgattgc tgataatcgg tggggaaata
     2641 gccgccctat tattttaagc aagcaacata tcgaaaagca aaaagcatgg caacaaataa
     2701 aaaagtgact ctgccagcca gcaaagagtc acatacaaat ttataaaact aggagaatta
     2761 tatcacatga ataagaaaat tgaaaatctt atcgaagaat tgaaacgtga atgccaaaag
     2821 caaggtgttt ctattatttg tacagcccaa aaagaagggg aacttaaaag tctcgtttat
     2881 ggtgagacaa cagaaatttt actttgtctt gctatgcaag aagaacattt agatgaaaat
     2941 ctcccattgt cagcacatat tatgcgtaga attgctgtgg atgcttacga acaagcgaaa
     3001 aatgaagaag aaaatcaacc ttcaaatcat acttttgtta ttaataacaa ggaagattta
     3061 gctgatgtga tgactcgtat tctcaagggg gaatttcaat gatgaatgaa aaaacaattg
     3121 atctactcat tattttattt ttcacgttag tgattgtagc gaaaagttat gtaatctttg
     3181 gcttgttatt cgcaattacc atgcttgtgc tttgcgtgtt agcaagcaga aaagaggtta
     3241 aacatgaacg agttagcaaa tcttgacaac tatttaactg atcctgatta tgctaaacca
     3301 ccatatgaag caccaattga tgaggaggat gaagatgagt aaatctacct tagaaatgag
     3361 ccatcaagaa tggcttgaag accgtaagaa aggcatcgga ggttcggatg ttggaacaat
     3421 tttaggattg aataaatgga aatctcctta tcaactatgg ctagaaaaaa caggacaagt
     3481 agtacttgaa gaatcaggaa gtgagcccgc ttattggggt aatgttttag aagaagtggt
     3541 tgctaaagag tttcaggaac gtacaggcaa aaaagtacgc agaagaaacc aagtatttga
     3601 acatccatta catccatttt taagagcaaa tattgatcgg gaagtagtgg gagaaaatgc
     3661 cattctggaa tgcaaaacag ccaatcaatt tctcggtaaa gaatgggaag gcgaagaggt
     3721 accgcttagc tatctctgtc aagttcaaca ttacatgaac gttctaaaca aagactattg
     3781 ttacatcgct gtcttaatcg gtggtcaaaa atttatctgg aagcggattg aacgagatca
     3841 agagctgatc gatacaatca ctgaacaatt agtagagttt tgggaaacaa acgttcttgg
     3901 aggtatcgag ccaattattg atggtagtca agcgacagct gatttcttga aagagaagta
     3961 tgcagatgtt gaagacgttc aaacgacgtt accaattcat ttcgatgaac tagttgaaca
     4021 gaaaaacgaa ctcaaacgga ctaagaaaga aattgaatca gctatccgtc aagtagacaa
     4081 cgagattatc agcgagctag gtaaacgtga agccagtatc ggtatcactc aaaaaaacat
     4141 catcagttgg aaatttgtcc gtacgagacg tatgaactcg aagaaactag cagagaaata
     4201 tccagatgtc gcaaatgatg aagagattta taacgttact gaatcaagaa ggctaaccga
     4261 aagggagatc aaataatatg gcaacaaatg aatcgttaaa aaatcaattg gcagcaaagc
     4321 cacagaaaca agttgcacca ggtcaattag gacttaaagc tttgatgaat acaccaacaa
     4381 tgagaaagaa gttcgaagag gtgcttcatg acaatgctaa tgcttttatg tcgaatgtta
     4441 tgactcttgt atctaatgac agttatcttg cagatagtga accgatgtct atcatgagtg
     4501 gtgcgttaac tgctgcaaca ttaaatcttg ggctagataa gaatttaggt tatgcatatt
     4561 tagttccatt caatagtaaa aacaagcaaa caggaaaatg ggaaaagaaa gctcaattca
     4621 tgcttggcta taaaggatat atccaattag cccaacgatc aggtaaatac aaagcattaa
     4681 atgtgatcga agtttacgaa ggagaactaa aaagctggaa ccgactgaca gaagagtttg
     4741 agtttgatcc aaatggtaga acgtctgatg aagtcattgg atatgttggc tatttcgagt
     4801 tactgaatgg attcaaaaaa actgtctatt ggaccaaaca agaaatcgaa gctcatcgga
     4861 ttgctaacaa taaagatcgc gataagacaa agttaagtgg tgtgtgggca tctgattaca
     4921 atgcaatggc acgaaaaact gttttgagaa atcttctttc taaatgggga atcttgtcca
     4981 tcgaaatgca agaagccacc acatcggatg agagagtcca aagggttcaa gaagacggca
     5041 gcattattgc tgaaacagaa gttgaagaag atattcctga aagaaaagaa gcagaggtta
     5101 tatctgaaga aaatgaagat gtacaaactg gattatttga tgcatctaat ccgccgttaa
     5161 acaaataatg agggagcttt ctcccttgct tttctagagg agaaatacga atgaacacag
     5221 gatatgtcaa attacatcga aaagtgatga attcattcgt ttggaccaat ccttatatgt
     5281 ataaattatg gaacttgtgt ttgatgaaag cgagtcatga gaatcgcaag atacttttta
     5341 atggaaaaga gatacaagtg aacagcggag aattcgtcac agggcgcgat gctatcacat
     5401 ctgagatgaa cgaaggcgtg aaacgtgaac atcaagtgaa cagcggttct gtatggagat
     5461 ggctaaaaca atttgaaaaa aacggaatgt tgaacatcaa atcaactacg aaatacagcg
     5521 ttatatcaat aaaaaactgg tctttgtacc aaagcagtga acaacaaatg aacatcaaac
     5581 gcacaacaag tgaacaacaa gtgcacacaa acaagaatga aaagaattat aagaatgaaa
     5641 agaataataa aacatcatcg tcgcaaccac gcaaaaagcg tgtttacgac accgactcag
     5701 tttactacat tctcgcggag gagttattca aacagatttg tcagaatcag gaaatcaaaa
     5761 agccgaatct gcaaagttgg gcagatgaca ttcggaaaat gatcgagatc gacaagcgga
     5821 ccgaaaacca ggtacgggga atgattgaat ggagtcagca caatgtgttt tgggcatcga
     5881 atattttatc tgctaaaaaa ttgcgagaaa aatacgacac aatggcagcg caagcaaatc
     5941 gtgattataa aacaaaacaa actaaaacgc ttgaatacga gaaatttagc acagatgagt
     6001 tgcctatttg agaggaggcg taggcatgga aactgttggg gaaatcatgg aaaagctgat
     6061 acagaaagtg cttgtccaac gtggcgaatg tcctgaatgc ggacagcctt tgtatggatg
     6121 gcgtacgaag aaccctgatg gctcagaacg ttgtaagcca acctgtatgc aatgtgggta
     6181 taaagcattg cgagttcagg aagacttaca aacagaacga atttacaacg agagcctgaa
     6241 agcaagagca atcaattttt tcaaaggtgg ttctgttgtg cctaatcaag cgttgtttga
     6301 ttgcacattg cagaattatc aaattgtcga tcaagaaaca agacaagcgg ttgaagtaac
     6361 caaacgcttt gttaattcag tcttgttagg aaatccaagt caccttgttt taactggaaa
     6421 acaaggaaca ggtaaaagtc acctagcgat ggcagcggct tgggaagtct tgaagcgatc
     6481 aaactacgat aaaaaaatct tatttatcgg gttacaggaa atgctggatc aaatcaaatt
     6541 ttcgtacaac aatcctgaac tcagaaaaac gattgaggga tcgttgattg cagatatcaa
     6601 aacagcggat ttagtcatca ttgatgatat cggttcagaa ctaggaaaag atgcatcaga
     6661 tagtcgagcg tttggcataa acacgctaaa ttcgttcttg gatgcacgac agaacctagc
     6721 aacgattatc acaacgaact tgcttggtga agaactgaaa aaagcttacg gtacgagaac
     6781 aatatcaaga atgtttgtca actctgatgg atttacgatg gtattttctc aaacagcaga
     6841 caagcgcata aaaccagtca aaggagcgat cgcatgaatt tgactaaaca agaaaaaaga
     6901 atctgtcgtc agataatgtt gcaaattata ggtgatcgtg acatggacga attatctcaa
     6961 caagagagtc gaatggttcg gaagataagt aagctaatta tttatcggga tacagaaaga
     7021 tttctcactg ttttaggtaa cgtctacgag aatccagagt tattggaggt agagtaattg
     7081 ccaaaaatat tagatgcatg ttgcggtagt agattgttct ggtttgataa gaacaattct
     7141 gacgtaacat ttatggattg tcgtcagcag tatgaagaat tatcaacagg tcatgtgatc
     7201 aatgttgatc cagatgtggt cgcagacttt cgcgatatgc cttttgaaga tgatgtgttc
     7261 gatatggttg tatttgaccc gccacactta agacatgtcg gcgaaaactc atggcttgcc
     7321 aaaaaatatg gaaaattaga cgaactttgg ccagaagaca tcaggcaagg ttttgcagag
     7381 tgtatgcgag ttttacgacc ttcaggaaca ttaattttta agtggaacga ggaacagata
     7441 ccactttctg atgtgttaga ggctattgga gaacagccat tgtttggtaa taaacgaagc
     7501 aaaacacatt ggcttgtgtt tatgaaaaaa ttcagctaac ggaggaaaca aaggaggaaa
     7561 agtaatgaag attgtattaa ataaatgttt tggtggcttt gggttgagcc atgaagcaaa
     7621 aatggaaatt tttaaaagaa aaaatattga agtattccca tacatcaata actttagcta
     7681 tgactcagat gatgaataca cgagatacac aggccaaaag ctaggttcga tggattttat
     7741 ctactatttc aaaaaagacc cgaaaatcga caaagttaca ggaatttata gcgaaattga
     7801 ccgactgtac ggaattgctg atgattccag tttttcaagt gattcaaaca gaggtgataa
     7861 ggacctcgtt gctgttgtcg aaaaactagg aagtgaggcc agtggaccat atgcaagtct
     7921 taaagtcgtt gatatacccg atggggctga gtgggaaata agtgattatg acggcgttga
     7981 aactgcacat tatggttttc aaacaggtag tatttagtcc actaatgaca actaaagagg
     8041 aggcagaagg atgagtgaag atgaatactt tgaacagtag tctattaacg acagagattt
     8101 ttaactggaa aggggtgtag tcatggacgc atcggaagta gtaaataaaa ttaatagtct
     8161 caaagaggtt ttcggagacg tcgaagtagt gataaacgca caaggctatg acaacgaatt
     8221 ttttaagcag attaccgaca ttagcattca gcaaggaatg gaagacgaag acggaaactt
     8281 tatcgatgaa gtagccattt tagtgacttg cgagtaagta attgacagct aaagaggagg
     8341 aagcggaatg aaactaaaag acggatttta ctccagcggc cacggcatcg gcggtttaat
     8401 gctagatatg ccgacaaaga atcctaaaac acgtaagaaa ccaaaattca aagtcggtga
     8461 catggttcgc tgcgaagcag aaggattcat ctatccattt cgtggatatg tagaacacgt
     8521 ctataatcac tcagcaatca ttcgcattga aaacacgatg gaatgtgata agtggttagc
     8581 gaaaagcaaa gagaatttag cagtggtgag attggtggac atggaagtta taaaatctta
     8641 attttgcttt tttacaacta tcctacaaca atgagcgtta ttccacaact ggaaggagaa
     8701 gaggcaattg tgaacatttt agagaatata gatattaagc aaacaaggaa aaatgctaga
     8761 cgattactaa aaagatacag aaatttagaa cgtttggtcg gaccagtgaa aatagacttt
     8821 tccgtgatga ctgttaccaa aaatttgaaa ttcacaattg acagtcaaaa cgaagaaatc
     8881 attgaagcga taagtactcg agattcggtt atcgaagcat taacacggct aagtagaatc
     8941 catttccagg tactttatta tagttattgt tttcctaata agatgtcaat gtatcaaata
     9001 ggagaaaaat taggatattc cgatagaact atcgagagaa tgaaggcagt agctttggtt
     9061 gaatttgctg aggcgtataa atcaggagaa ctcatttcac gtacaaaata aaaaaagtcg
     9121 gattcctccg actatgaata atatttccga cataagtatt atatcataat tgggggaatc
     9181 agaggatggt acttttcgat gtaaagaaat atgagacacc aagcgcgaaa gatgttgata
     9241 tggaacgcac aaaacataat gtcgctgtgt ttctttcagc atatctatca gctagatgta
     9301 gagtagggca acatcgagaa ccaaaagtga cagcatctta ttccttggtt ccaccttcta
     9361 cagctgatca tatatttgaa gcagaaagaa tgctgatcga taaagaagaa gcacaggaag
     9421 aatttgagta tctgcataaa ttgtttgttc gaggctattc agcgatacag catccgcata
     9481 agcctgatgt gactgaaagg cgcaagaaga tattctatga tcgttatatc aatggtctgc
     9541 ccatttatgt aactgctcaa aggaataata ctagcgaaga atcggttaaa gtagaatcaa
     9601 acagaattat catccaattt gcttcatcgt tagaactggt tgctttcaag tagccagttt
     9661 ttacactttt tatacccttt tattaccaat ttggtttcca ttttatacct tttttatacc
     9721 aatcacttac ctattcaacg ttgtattatg atagtgtcga aaaattagga aacaggatcg
     9781 acaaaataaa atgtaaggga ggaaatctcc ctcatcgttt aattaagctt cgataggcag
     9841 caacggaaat attaagaata aggatgtgaa tttcaactcc ttctaaattg ttcttattat
     9901 ctatcatccg ttgctgtcta ttgttttttt aattattcac acgataacta aaggtaagtg
     9961 aagagaaatg attccattaa taatttcaat ttttgcgctt tgtcttaatg tatatatgat
    10021 tggatttaaa aatgggcaaa ataaaaaata gtagcagcca agaataattt tatagtgtca
    10081 ctgtggcgga aagggtagac gctaagcatg tgtgctaggt caatgcttcg gcaaccatgc
    10141 aaggttcgat tccttgccag tgactttggc aaccgaggca tcggcggttt aaaaatatag
    10201 gggtgcgcaa tttcgtacgc gttttgtgca tcgtgtaggt tgctattaca taactggtta
    10261 ggttagattg agatttggga ttcggtacaa atgaatcgtc aaatgtctca agcacaggat
    10321 cggaaacgtc cctgcctgtg cattacatat tagatcactc tttgagtggt ctttttcttt
    10381 acataaagga ggctacataa tgagaaacta ctggtatgta tcgctaacta atgaatatcc
    10441 tcgaaccatt gatgattgtt cagtgcgtgt tgtgcgttct gtacaaatca aagggaagta
    10501 ctctattgtc gaaatgggga gagaagcaga accatgtgag attgatgcgt gcaagctcgt
    10561 ttattgcggt catggtttct atgatgaacc aaacattcaa aataatatta acaagaattt
    10621 gagggattag aatgcaagaa atggcttaaa aatctccaat caggacaaat caagttagac
    10681 aaagtttccg atttaaagat attgattgaa gctgatttaa tgctaaaaga tattgaaaat
    10741 tagaaaacaa aactcaacct aaacagaatg tgaggtggtg tgtattgaat ggcaagacaa
    10801 cgtgatccaa gacgtgatga agccaaaaga atttggttag aatccaacgg agaaaagcag
    10861 ttaaaggaaa ttgcatctga attaaatgtt tcagattctc aggttagaaa atggaaatcg
    10921 caagacaaat ggagcgctga attgattagt aacgttacca atggcaaaag taacgttact
    10981 aatcaaggtg gcgctcctat tggtaatcaa aatgctaaag gtaacaaagg aaatagccga
    11041 gcttctccgc cagtgggtaa taaaaacgct ttgaaaacag gtgagtatga aacaatattt
    11101 tttgacacgt taaccgataa tgagaaggac atctattcta gtttgaatga tgatccttct
    11161 tttgctttgt ccgaagaaat acgacttctt aaaataagac aacttcgaat gatgaaaaga
    11221 atccaacaag ctgaagctgg actaaatgat gaagaagtcg aacgattgca gcagctaaga
    11281 aagattaaaa ctccgattga aaaaaatggt aaaaagctag aaatcaagcg tgaggttatg
    11341 caagatgtgc agattagcag aaaaaaacat cgcaaaattg atgatattct ttcaattgaa
    11401 gattcattga ctcggattag caaccagtta gctaaagcca tcaagcaaat gaatgaactt
    11461 tatatgaatg aatacagaac tgatttaatt aaagctcaga ctgataagat ccaagctgag
    11521 acaaatgaaa ttggcggaaa taattcaggt gaagaaatag aagaatggaa acaggcagtt
    11581 ttaaatgccg caaacaaacg ggcggtgaaa gaaaatgaat aatgaattta ttccttttgc
    11641 tgatattggt tctgccattg attattacta tgataaacca gtagcttttt gccaagatat
    11701 tttgcatttg aatcctgatg aatggcaaga aaatgtttta aatgatttag ctgaattttc
    11761 aaaggtttct gttcgttctg gtcaaggagt tggaaaaaca gcattagaag caggagcaat
    11821 actttggttc ttaacgtgtc gaccctacgc taaagtaata gcaacagctc cgacaatgaa
    11881 gcaactttac gatgtacttt gggcagaggt agctaaatgg ttaaatgata gcttgatcaa
    11941 aaacttactg aagtggacaa agaccaaaat ttatatggtt ggtgattcag agcgttggtt
    12001 tgctacggct agaacagcga ctaaaccaga aagtatgcaa ggttttcacg aggaccatat
    12061 gttgattgtg gtagatgaag cttctggtgt gtctgatcca attatggaag ctattcttgg
    12121 tacgctatca ggttttgata ataagctgtt gatgtgtgga aaccccaata atattgaagg
    12181 tgtcttttat gattcccata attcagaccg tgataaatac agagttcata aagtatcaag
    12241 ctatgatagt aaacgtacaa acaaagacaa tatagaaatg attcttaaaa aatatggaaa
    12301 agaaagtgat gttgctcgtg tccgtatttt tggagaattt ccgaaaggtg cgttggattc
    12361 atttatcagt cttgaaacag ttgaattggc tacagaaaaa caaattagtg attctttagt
    12421 caataaaaca aaggttgctc atattggtgt cgacgtagct cgatatggtg atgattctac
    12481 gattctcttt cctagaattg ctaccagggc attggagtat gagaagtatt caaaacgtag
    12541 caccatggaa acaacaggat atgtcatcaa catggccaag aatctaatga gtcaatatcc
    12601 gagtattgat aaagtgatga ttaaagtcga tgacactggt gtcggaggtg gtgtaaccga
    12661 ccgcctagaa gaacttatag aagacaaaca ttatcctttt gaggtgtttg gagtgaataa
    12721 cggttcaaca tcagaagacg atttttacga taatttaggt actcaactat ggggaaacat
    12781 caaggaaatg ttagaagaaa atatgacagc aaatcttaac ggagaacagc ctgttattga
    12841 attgccttct gatagttcgt taatcaaaga attaagtact cgcaaattca aaatgacaag
    12901 tagaagtcgt atacgtttag aaagtaaaga tgatatgaaa aagcgaaata ttggtagtcc
    12961 cgatattgct gacgcactgg ctttagcgtt ttatgagcca ccaagtcact atcaatttat
    13021 tcaattttag gaggtgagct tttgattagt acagtattat ctttagagag atataagaag
    13081 ctacgtgtta aatatgcaac acaaattgaa gatggaatgt ttgatccgaa tggttttata
    13141 gaagatatga aaccattttt tgctgatcgc gaaagaaaat atctagctta tactagcgaa
    13201 aagaatgaaa tagataatag accaaagcct aacactgata ttgtaaaagt taataataaa
    13261 cttcatgctg gtatgtattc aattgtcgta gaccaagcag tcaatcattt tactggtata
    13321 cctatcaaat gggattacga tgtatcggaa caaaaaagaa cactcattca aagattaaaa
    13381 gataaattct taaaaaatga tatagaactt ccgacagttc cagaagcttt taacaaatta
    13441 acaagcaatc ttgattccat gagattcgca atgcttgatt ctgaaactgc aacttttcaa
    13501 ggagcttgtg gagtagcttt ccgattgcta gagcctgtgg aagaagatga tggttggaag
    13561 ttaagagcaa gtaatattga accttggaga gcagaaagat atggaaatgc cggaatctat
    13621 atcaaagaaa agtatgactc ttaccagaaa aaattttttc aagaaatgaa agttatgaca
    13681 agaaataaaa ttctgacata tgcttgctat ggtgatttga attttgttac aagcggaacg
    13741 ttcaaaaaaa ttgatgagac cgataaccct ttggggacga ttaccttggc agaatttaaa
    13801 aataatacga atcgttattg tgattttgaa gtagctgagg aaattggaga tgcaattgat
    13861 cgtgctttgt ctgatcaaca aaacgaaatc gaacaattta agcttgcgta catgcttgtt
    13921 actggcacaa caatgagcaa aggcactgct aaagaaatga tgaatcagct agggattatc
    13981 aacttaaaag cccctactgc aaaagctgaa tatgtcacaa aaaatttagc aaaagatttc
    14041 aatgaatatc atatggatct attgaaaaaa cagttttaca ccatttgtaa agcaatcgat
    14101 tttaacgatg aggtgtttaa atcaaacagt tctggagaag ctcgcaagtg gcaaatcatt
    14161 agcctagaag cgaaaacaaa tactaaagag caatatttta gagaaggatt gaaagaatgc
    14221 gcagaaacaa ttgctgcttt tcttaagttt catgacaaag tagaaattga gcctgaaaaa
    14281 attattttta ctttctctag atctttgcca actgatttaa gttatttagc tgaagcttta
    14341 cctaaacttg caccatacgt atccaaacga actattcaga gccaaattcc atttgtaaca
    14401 gatgttgatt atgaaaatga aatgatggaa ttggaaagtg gaagtgctta tccagatagt
    14461 gaatacaatt ttggcggagg tggcaatagt gacgatagaa acgaagtatt ggaccaaacg
    14521 tcgagaactg gaggatcaag caaggctcaa acaagaaaat cagacactta aaaaattaac
    14581 tagtgtattt cctgaagcac tgaaagagat acaagcaaaa ctattatcac aagctgactt
    14641 acacaatatc acttatccag aaatgatgga gttttacagt acaagtaatc agaaaaaata
    14701 tcgtgaatat gtggaaaaaa attataagtc attaaaaatg tatgatgcaa aatacaaaga
    14761 gtttatcgat gaattttttc caccatttga ctatgcaaaa gtcaatcgct tattacaaat
    14821 acgatcagat gtatttaaaa ttcttgcaga atatgcgatg gatgcagatg tgaatcaata
    14881 tttttctgat cgcttagagg aaattcttca aagaacatat tcttctaatg ctaatgtttt
    14941 tgttcaactt ttaaacgttg atataccaaa ttatttacca gaaaatgaaa ttaaacatta
    15001 tttgaactat ccatggtcag gaaagacatt ttcaagaaga ctttggggaa atatttcatc
    15061 gcttgaacag aaactctcta atgctattgt aaaaagtgtt gctagtggag aaggcgttat
    15121 acacgcatta aacaccatga gattagactc agaaatttgt gacatgttta agttagaaga
    15181 atcaaagtat aacaaagcga tagaaaatct cgttcgaacg gagtatgcaa aatttgcaca
    15241 agatggtatt gaaaaatcat atttagaaac aggtattgag gaatacaacg tattgactgc
    15301 aaaagatgag agagtttgcc ggatttgtgg aggaaaggca agtaagaatc cctataaact
    15361 gaaagatgct gtcataggtg aaaatcgagc acctttccat agtcgttgta gatgtacgga
    15421 tgttcctaat ttaccaaaat taggaaagga tattgatgaa gaatatgacc gtttatttgg
    15481 cgatttatta gatgagtttg cacatgattc ttttggaatt aatttgaaac ggaggaagta
    15541 gaatgaaaga tttttttgaa gcagtactaa caattaatgt aaatgctgat attgcagaag
    15601 cctacaaaac agctattgag tctgagaacc atcctaatgg cttgagagac cattggaatg
    15661 gcaattatgc ctacgtggtt attggcgatc aaactgttaa ttatcaagat aatactccag
    15721 ttgataagaa taccgttaat ttaacgattc aattattatc tcattcatta ccaaatttaa
    15781 aagaaacagt tgattggtat gaaaagatgg gatgtattgt tgttagaact gactacaaag
    15841 aaggaaagtc tagtaattag gcttttttat tttgtccgaa atgacgttaa actagcgcaa
    15901 tactgggctt ggttgaatgg tggggcgcaa ctattaaaac tcaaagcaat gcggggcgtg
    15961 aaaacgaatc gtggggcgaa aggagaatga gcatgaaaca caaatcatta atgccaatga
    16021 atttgcaata ctttgccgaa ggtgacgatc aaaagttttc ttttgatgac ttcaaatctt
    16081 ttgtggaatc caatgaagaa gctcaaaaat ttattcagtc acaatctcaa agtgttgccg
    16141 acaaacaatt ggaagcttgg aaacaaaata acttagataa aattaaacag gataccatca
    16201 aggaatatga ggaatctaag aaaaacaagt cacctgagca aattcaactg gaaaaactac
    16261 aagctgaatt tgaagcagaa aaagcgttgc gtgtgacaag tgataataaa gcatttgttg
    16321 cagaacaaat tgctggatta gaactagatg gagagttaaa agagtctatt tctcaattta
    16381 tgctaaataa tcttgttagt tcggatacag atttcactaa gaatgctgtt gaaggtttta
    16441 caagtgtttt gaatgcaatt aatgagaaac atgcagatgc attaaaagaa ctacaaatga
    16501 agtctgcatt tggtggaact caacaatcga ataaccaggt tcagcagaac aatgaaacat
    16561 taacaaatcc agaagaacaa ttaggacaaa ttcttcaaca atttaactag gagagtgaaa
    16621 aattatgaaa aaaacatctt taaataattt agagtatttg gatatttcac cagcgattaa
    16681 tgctatgcaa gtaccaaata cacctttttt aagctattta cttggtgctg gaaaaacaga
    16741 gccagcaaac tcgacagaaa ttaaatggcg tgaatatgat atcaacaacg atgattcttc
    16801 tgaaaaactt gagggcggag aatatccaga tgctgaatca ggtcgaactt ggtttaacaa
    16861 ctatactgaa atttttagaa aatcaacctc tgtatctggt acattagatg ctattaatgt
    16921 gaatggagtc ggaaatgaat taactaatca agtagcacta cgtggtatgg aaatgaaaat
    16981 tgatttgaac cgaaaattga ttactggtgt aaaagctgat gaaaatggtt ctaaaggtcg
    17041 tcgaatgaat gggattttga acttgatcaa ttcagcaaat aaggcagaaa cagccactgc
    17101 gggtgcagta acaagaaaag atatcgatac tttatttaaa ttgatgtatg aaaaaggtta
    17161 tatgggagaa aaactatgct tgatttctcc agatatgcag gagttaatga ctgatgagtt
    17221 agatggaaaa tcaacaaaaa ttgttcagtt cggggaaaga gtaacttttg gattgcaaat
    17281 tggaaatatc gtgtctaatt acggtacagg tattgctcta ctagaaccat cattgccaaa
    17341 aggaacaatt gccgcaatcg atactaatta tgtgaaacta cgtccattac gtgaatggag
    17401 agcagaagaa cttgcaaaaa caacggattc tagacgtatc ggtcttgtag gtgaatactc
    17461 tcttgaatac aatgcttcaa actctggggc aattttaaat ttaaagtctg aataaaaggg
    17521 agttagtact cccttttttg ataggaggaa ttacagtggt aaaaaaagat gaaactaaaa
    17581 aagatgaagt cgtgaaatat agagtaggta aaactaaaaa ttttgttggg tttgttcatc
    17641 ctaaaactcg tagatttatc acagcagatt caaataacga atttatcatt tctatagatg
    17701 ataaagaagc aattgcaatt ttggaagatg caattgatgt taatgaaatt taggaagtga
    17761 tctgatggat gaatcgctaa aaacggaaat cattgagtct acaaaagaag attttccaga
    17821 tttgagtgaa gaacgcataa ctaatttatt agaaataatt ttgctagaaa ttgaatcata
    17881 caacacttgt aaaaatgata tttcatggga aaagttaaaa agcgtgatta gtgaagtgtt
    17941 gtataaaata ataaaaaatg aatcagaaaa aacagtatct tcagttagac gtggcgatac
    18001 aacgattagt tatgcttcaa caacaaatga tgttagtgag ttacttctag gctatggtga
    18061 tttgatacga agagttattg gttgtggagg attggagttt ttttaatgaa tgaagcagat
    18121 attttagaaa ctacttatga agatagttgt attattgaaa gactgacgga cattgaagat
    18181 tctaatacaa atattactat tcaagattac aaaaaagtat atgataatcc tatttcttgc
    18241 gctctttcac aaggtcaaat cgatggacta gcagtcatag aagatggaga gatggtaaat
    18301 gtttcaactg acacatataa attatttgtt catcctaaga ttaaactaaa aaaaggagat
    18361 cgaataacaa taactcaaaa ggccagtggc ttaatttttt ctctatttgc tactaagcct
    18421 ttttactatc ctagtcattg tgaagtgaat ttgataggaa gtgagaaaaa tgggtaatct
    18481 caaatatgaa tcaaatgcag aaaagatcat tgagaatttt aaaaatatga ctgtaattgc
    18541 tcaaaaagaa ggaatatcct tcgttaacga ttcaatgaat aaagtcgtta gtttagctaa
    18601 accattaact cctgtaaaat caggtaattt aaggcgagga tatcgtgtag taaaagctag
    18661 aaaactatca agcggtcgaa ttgttggaga agttataaac aatgaacatt attttaaata
    18721 tgtagaagaa ggtcatagga ctaaaaatgg tggctttgtc aaagggaaat tcatgttaac
    18781 tcgtgcaacg aatcttgcaa atatgtctta tattcctcga agatttaaac aaatggcaat
    18841 aaaaatcgtt aagaaaggaa agtaacatga aagatgaaat cattgctgca atcagtagca
    18901 aattaaaaga aatctatcct gatgggacaa tatatcttga ttcagttatg cagtcaacta
    18961 aagattttta tttcgtttta tcagtaatgg aatctggaac tgaaaatgta ggaattgata
    19021 ttcaaaatgt ttctttctta attgatattg cattgattga taataaccct aatagaaatt
    19081 taattaatga attagtctca cgttgtggga ctttttttaa tacgattaca atcgatgagc
    19141 aaatattatt tccaaaagcc tatttacctg atgaagcaga tggtgttcaa catattcgtt
    19201 ttacattaga atttccacaa tatattgaat ggagtgaaag ataaatggga gaaaaaagaa
    19261 gtaaaaccgg aattatttct gtcgaaaaac ctacttggtt tcctttggaa gatgagacag
    19321 ggaattttcc ggtatatggt actgcgttgc caatgggaac agcagtaagt atcaaaccaa
    19381 cagctaatta tgaaacaaca caagattatg gggattcagt ggttcaagat caatttacag
    19441 cttttggtgg tgcagaagtt gaactggaag caaatggata tactcataaa gttttatcta
    19501 caattactgg agggaaaatt gttaaaggtg gtgccttgcg ttctggagaa gatattgcgc
    19561 aagatggtgc gtttgcatat agacgtaaaa aatcgaatgg gaaataccgt tatacggtct
    19621 tttataaagg acagtttgct ctagattcag atgaaacatc aacgattgaa ggaagtaaag
    19681 taagttttac tcatccaact tggaagggtt catttgtaga tgtaccagga cttggatata
    19741 tgtattcagt tgatgaagat gatgaaggcg tggataaagc aatgatcgga aattggttta
    19801 caaaagtagc aattccaatt gaagaagcag aactttcagg aggtacagaa taatgtcaaa
    19861 atatcaaaca acgattaaat taacgaaaaa agacgaagaa ggtaaatatg agcaagtaca
    19921 atttaaatct gctgaatttt taccaggaac agttgtagaa gatgctgcag gagttatgga
    19981 agaaatgcaa acagcgactg ataagcaatc agttaaaaaa gctttaagtc gtgcttattc
    20041 atttattgca gatactttat ttgagggaca atttactggt gaagattatt gcaaaggaat
    20101 tgatgctcgt gagattgcct cattgacagg aaaattattg aagtctgtta ctgcaggttt
    20161 tgatgaaact tatacagaga cgaaaaaaaa gtaagtgagg cgctcaagtc accttcattt
    20221 aagtattcga ttacttaccg agaattagat ataaagacgc aattactcga agcaggttgg
    20281 acgttaccag aaattgaacg tactgacttg gatgagttaa tgcgtctttt tgcttttaga
    20341 gatgcggtaa aagagcatga agatgttgag tactatgata atttcactca attttaggag
    20401 gtgatacttt gaataacgat gacctaattc tgaagatgat actagatgaa tctggtttta
    20461 ctgccggtat gaataatgct gtcaaaaagt tgaactcttt tgatgaaaca atcgaaagaa
    20521 aaagtagaaa tagtggcagt tcattaggta gtatttggaa aatatttgct ggaagttttc
    20581 tagctagcgg agtaactaga atcgtaggag ctggctttga tctaatcaag ggttccataa
    20641 gtggagcggt tgatcgagta gatacgatga ataacgctct acgaaatttc caaaatatgg
    20701 gatttagtaa ttcagaaatt atgaagaata tcggaaagaa tgggctttta tctcaaggta
    20761 ttcaaggact tcctactgct ttgaatgatg cgataagtca tgttcaactt cttgcttctt
    20821 ctacaggtga tttaactcgt tcaactcaaa tatttaaagc tttaaatgat ggaattcttg
    20881 gtttcggtgg ttcaactgat caagttaatg aagctgttat tcaattatct caaagtttct
    20941 caaacggaaa agtagacgca caaacttgga actcaatgat caacgctcaa cttggaccta
    21001 ctctttctgc tattgctaaa aagatgggaa ttacaatggg agatctgaaa gaaggtttat
    21061 ctcaaggtaa gatttctgtt gaagaattcc aaaatcaatt aatagaaatg gataccaaag
    21121 gtggcggagg acttaaatca ttaagtcaaa tcgctaaaga ttctactaag ggaattaaaa
    21181 cctctataca aaatgcaaaa acagctgtta cacgtggtgt tggtgaggta atagaaggat
    21241 taaataaagc attagtagat tcagatttag gtggatttaa gggaattatt gataaagtgg
    21301 gcagttcaat ggaatcgttc ttaaaagtaa ttgctgcaaa tattcctaca gcagtatcat
    21361 ttttaagtaa tttatttaac gaaattcaaa aatttggttc tgctttgaaa ttcatgatgc
    21421 cctttcttgt tcctgcagct accgcttttg gagcgttcat gtttcaactt aaaggtatac
    21481 cagcaataat aaaaagcttc aataatttta agaatgccat aattggcgtt ggaaattcat
    21541 taaagattat gggggcaata gctgctgcta atccatttgt tttaattatt ggtgcagtcg
    21601 ttggtgcaat agctgttttc ggttacttta tggcaaccaa tgaagagctt agaaacaagg
    21661 ttatatctat ttggaatgat gtgaaagatt ccgtaattgg tgtattaaaa aatataaagg
    21721 actggggaat tgatacttgg aattctgcta aagaaatggc atcaaatgca gttgagggtg
    21781 tcaaagatgc ttggtcagga acaaaggaat ggttttctaa cacctggaaa ggtattaagg
    21841 atggggccac aggtttattt gataaaacag tagagacttc aagaaatgca gtcgatagtg
    21901 taaaaaatgc atggtctaat atgaagaaat ggttttctga tacttggcaa agtataaaag
    21961 attcagccag agaaaaatgg aatggaatca aaggttctat tatgtcagtt gctggtccat
    22021 tgattacagg tataaagaat gcatttttac atgttacttt ttatctagag accttatgga
    22081 ataatttagt tgagattggt aaaaacgtct ttgagatttt aaaaaatgtt atacttgcgc
    22141 cggttttgtt tattacctcc atgatttctg gtggatggga agaaacaaaa aataatatga
    22201 ttgctgtttg gaataatatt aaagaaagtg ccataaatat ttgggaatct ataaagaata
    22261 tatttgtaag ttattttaca aatatttatt ttgctgcact caatatttgg acagggttca
    22321 agcttacatt gataaatatt tggaatgaag tggtaaatca agctaaatcg atttggttaa
    22381 acataaagta tttttttatt aatctttgga ttgatataaa atattttgca attcagaaat
    22441 ggattgaatt gaagttttct attattcaaa cttggatcga tttaaaatat aatgccatta
    22501 ctacttggaa taatattaaa cagtttttca aagatacttg gaaaaatatt aaagatacgg
    22561 catacaatac gtggatttct ataaaaaata ccatgattaa tacatggaat aacattaagg
    22621 actctttctg gaatattgtt actggaattg ttaattctgc tgaaaatgca tggacaaatc
    22681 taaaaaatgg tgtttcaaat gctattaatc gggtaaaaga aatctttaat tcgttaaggg
    22741 aagtcaattt atttgaaatt ggcaagaaca tcattgatgg acttataaat ggtgtaaaag
    22801 aaaagtggaa tgctttgaaa gatactatca aaggtattgc aggtaatatc aaaaattgga
    22861 ttaaaggagc tttagatatt cattctccat caagatggat gcgtgatatg gttggtaaaa
    22921 atattgttca aggtattatc gttggtattg ataaagagca aagtaagtta gatcaaacca
    22981 tgacaaattt agtaaaaaca ccgtctgttc aacctgtagt aaatggaata agtcacctac
    23041 caattacaca aacaaagcaa aatatatctg ctagtgaaac aaaagaaatt catttacatt
    23101 taaatgttta tggagattta cctgattcaa tggttcggaa gattaccaca aaaattaaaa
    23161 cagaattgac aagacaaatg aaacgagatg ctggtgcagt aggaggaaca ttatatgcaa
    23221 cttaagagag gacaattttt tattaatcaa cattattctt ctgaatttaa tgtgtatatt
    23281 caaaacaggc ctgcttctgt ttcagctagt cgagtaattg aattgagaga gcgagaagga
    23341 aatgattcta tcattattga taaaggctat tacaaaaatg tgactagaaa gattgagtgt
    23401 tactataaag caccttcaat tgatatggtg caggagtggg aagatcgaat cactgaatgg
    23461 ttagatatgt cgtcttatag tgattttatt ctttactatg atgaacaata tatttatcaa
    23521 gctgtagtaa tagaaggacc tgaatttaaa ggaacaagaa aaacaggaaa tattgtccct
    23581 tttgaattta cagtgagtat tcgaccattt aaggaaaatt acaatggtag atttactatt
    23641 cgacaaacag aaacttttga aatttataac ccagagaagt attcttcaaa accgcttatt
    23701 aaattgagtg gttctggaga tgcttctttt tatattaata aggataaata tgatttgaaa
    23761 tcgttggaca gagaattatt tatagattct aaattagaag aggcttatcg aaaattagat
    23821 ggtaatttag aacatcagga tcaggtcacc ttatttttag attttccatt tttatatcct
    23881 ggaaaaaatg aaattaaatg gacgaaaaat attcattcat ttgaaataat gcctaggtgg
    23941 tggagaaaag tatgaaacca agaatatata gtcctactga aacagatttc tcaacgaatg
    24001 gcttaggaat tttaaaggat tgtacaagat gtggaatata tgaagtagct aatggaaaat
    24061 atgaattaga gttggattat cctttaggaa ctagatttga tgaatatttt gaaaatgact
    24121 atcaaataaa agcaaagcca aacgatcaag aagagtatca tatctttttt attgatgata
    24181 aagatataga tactttttta aatacagtaa ctatttatgc tcagagtcgt acaaatcgac
    24241 ttggaagacg ggtagtcact cttgtggaag tggactctaa aactggtcaa gaagcgatat
    24301 caattattga aactaaaatg gataaaaaat ctgacatacg actttattct gatattacgg
    24361 ctgtttctag cacaatcttt gaagcgagaa atgttttaaa ttgtattgct ggtgaacaag
    24421 gatcattgct tcaatattgg ggcggagaaa ttaaacgtga accatttaag ctttctttgt
    24481 taaagcgaag aggtcgcaat aatgttggaa cgattcggta tggaaaagat atgtctggtt
    24541 tgaaggtcaa attagattgg acaggtataa aaacaagaat tattccatat gctgatcctc
    24601 aaagtgaagt aggtacgact aatcgaattt atggttcgcc agtagatagt gcctatatta
    24661 ataactatcc tgatgtctat acagaacatg ttcagtttac agaagaacaa ggagtaaaag
    24721 acattaagag cttaaataaa atagctaaaa attactttaa aacgatcaat cctggctgtg
    24781 ataagcctaa agtttctatt acggttgaat ttgataagtt gactgatagt gaagaagcga
    24841 aagaatttgc gaagattaga aattatggtc tgtttgatac atttaaaata tatcataaaa
    24901 aatataatat ttatcttgaa tcaaaggtta gtggactaca atacgattct ttatctgaaa
    24961 aaactttgaa attagaagca ggagacattc aagttgcttt ttatcagcaa caagctgtaa
    25021 ctattcagga taaattaaaa gattatgcaa cgaataatta tatgagtgat tttaatgatt
    25081 atgtttcttc aatgattaca ggtcaaggca gtgcaggagg atatgtagtt ttatggccaa
    25141 aagaaaaacc ttccaacatc tttattatgg ataatccaga tttagaaaag gcaagagaag
    25201 tactaagaat gaataaaaat gggattgctt tttctaagaa aggatggcgg gggcctttta
    25261 attcagcttg gacattagat agtatattta atgccaattt tatacaaact ggattaatca
    25321 aagcagatat ctttcaaaat tcttttaaca agactggaga tgtattgaaa ttagttaatg
    25381 gactactcca aatttggaac aacaaaaaga aaataatgga gttaactaaa aaaggaatgg
    25441 aattttggaa ttctaagggt tcaattggaa cgattggaac aactgattct gttggtaatc
    25501 cttttcctgg ggcttctact ccaaccccta ttgaagataa ttctttagtt attcgtacaa
    25561 atggagacgg caaatatatt ttgatttctc ctaaagtagg aaaaggatta gttttattag
    25621 gaaatggtaa agcaatttat tttggagact tagatgtaca aggaaaactt acagttaaag
    25681 gaaaagaaat aattcctgga caaggtggtg gtccatcggg aggtggagaa tctactggtg
    25741 ggtatcctag tgaattaaaa acagatgcag aaaagagagc ttggagaatt tacgatattt
    25801 tgtgtaataa cggatttacg aaacaatctg catgtggaat attggggaac attcaacaag
    25861 aaacaggagg aacttttgat cctgatactg ttcaaatagg tggaccagca tacggattag
    25921 ttcagtggga tggttcttca tatcctcttg ttggtccagc aacatgggat ggaaaagttt
    25981 atgttcaaaa cttatttaat gctgcaggta ttaaagaacc aataacgagc ttagatgcac
    26041 aagttcgatt gcttatttgg acatttacaa atggacaatg gatgggcgta gtacaaccta
    26101 cgacggttga tggatttaag gcctgtactg atccaagaca agcagcatat gcttttgaac
    26161 gaaactatga acgtccggca gcgacacatc ctgaacgtca agattatgca gttaactggt
    26221 ataacaaatt taaagattta aaaccaggag gagctactgg agaagcagga ctaaaacatt
    26281 tagagtcttt gattggacaa cgaattggca atggtcagtg ttatggcttg tctgcagaat
    26341 attcaggata tctgggtggt tgtggcatgg gtgctggaac aaaatatggt ttaactcatg
    26401 tgataggaaa tacttctgca gcatctgata ttggtattgc ctatgattgg tctgctgttg
    26461 gttggaaagt gattcaaaac cctagatatg atcaattagt agttggtgca attattaatt
    26521 gggcaagagg tggacaagtg ggttcatggt ttgcagatgg aacttatgga catactggcg
    26581 ttatccgagg cttagctaat ggtcgtatgc aaacttatga acaaaacaca gagttaggta
    26641 tgatttgtgg aaagttagat cgccagtatt atagtgcaag tgcaatttct tccattgtca
    26701 taccaccaaa atagggaggt gatttaatgg caaagtggaa tgtcatatta agtacaacag
    26761 aaccctataa ttacgtgggg atgattcaag ttcgacaagg caataagaat acagaggtta
    26821 tggaagcgac tatagttgaa aatggtcttc cctacgattt atcagaatgt aaggtatatt
    26881 ttgaatcagt tgtaggtggg aaatatccag tccaattaga aacaaaaatt gtggatgcta
    26941 aaaaagggaa aattaactat atttttgata aatattccat gcagtgttta catcgacaaa
    27001 cagccaattt cattatattt aaaggagaag acttgattgg aacaactcaa gacttctctt
    27061 attttgtcat taatgctgtt tcaaaaacag aaggagaaat gggttcttat tggcaatcaa
    27121 tcgaagattt aattgcggat atgacggact ttattaatga aaataaaggc gattttacgg
    27181 actggatgaa tgaaaggaaa gaagaatttg aacgttggag acaagaacag gaacacagtt
    27241 tccaagattg gagagaagga caagaatcag actatttggc atggtttgaa tcaatcaagg
    27301 atattttaaa gacgattgat ccaggtggag tcatgttagc cgaactaacg gatgcgcgag
    27361 tagatattca aggagttcgt catgcgtcta tttcagagcg tttgctggca gatatggact
    27421 atttatatca gaaattgcga gcaacgcttt tcacgattga atacggggag attgaagtga
    27481 ctgatatttt gcaggatgat ctcttttcag ataatcatga agtcgaaaaa gttggaactg
    27541 tagcattccc gattgaagaa ggagccttga tcatcgcaac cgttgatgat ccaaagcaaa
    27601 atgtgttcac tcttgagaaa gttggggtga tctaatggct aaaactaaac gaatgatgga
    27661 aacggatgaa aaaacgggtg tacaacgcca attctttcca atcacacatg cttccgcagt
    27721 tcttgggtta gaagaaataa tagcaggaga agcaacagtt ttatctgtta atggaaaaat
    27781 tggagccgtc gtcattacta aagaagattt gggattagag aatgttctca cagaattacc
    27841 ctatgcaagt gaagaagatg acggcattat cacggcagaa atgtatcaaa aaattttaaa
    27901 cagtggagaa ggtgactacg tgttgccagt tgccactatc gaccgtttgg gtggcataaa
    27961 agttggtgaa ttattgacga ttgatgagac agggaaagtc tctgcagtca gacaatctga
    28021 tgtcaatttt tcgctggagt taaaagaaaa actcgattca ctgaaaaatt atactgctgg
    28081 agaaaacatc actattgatg aagatggaac aattagttct acaggtggta gtgggactgg
    28141 tggtgtcaat cagtcatatg tagatcaaaa attccaagaa gctgtaaatc aagcagaaaa
    28201 ttacacaaac gaaagaattc caaattttac ttttgaaaaa attggggagg tatagagaat
    28261 gacagatatc gtaaaaataa aacaaagcaa tgtacaggtt tatccacaaa ctcattggaa
    28321 tgctatagaa ggcaaaccaa caacggtgaa gggagataaa ggcgatcctg gccaagcagc
    28381 aacaattacc ataggaaccg tttctagtgg ttcaaccgct tctgttacga atgtaggaac
    28441 atcatctgca gctagattta attttgtttt accaaaggga gataaaggtg atcctggaat
    28501 aaatgccaca actacagctg tagctacaac tacagcaaat gggttgatgt cgtccacaga
    28561 taaaactaag ttggatggaa ttgcagctgg agcacagaaa aatccaggta atgctacaac
    28621 tacgacagca ggtttaatgt cagcaactga caaagctaaa ctcgatggat tagccaatat
    28681 tacatttgag aaagtgggga cggtttaatg gctgatattg tgcaattaaa agaagacgga
    28741 gttgctaaat acttaaaaac gcatgtagaa gctattgatg gtaaagaagc attggtgcag
    28801 acagatggag accaagccat tgcaggacat aagaattttt caggttctgt aacaatcaat
    28861 aataaacgtg ttttgacgac tgatgataac agatatgaag tggtaaatct ggttgtcact
    28921 aacggtaata cagggacagc aaagctttat cgtgaaggaa aaacagtttc tatatatttt
    28981 gtggctttaa acggaaaaag tagtggcggg aatgattcgg ttattttaac tgttccagaa
    29041 ggctatcgg
//
LOCUS       DAFLWQ010000032        27587 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.033, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000032 DAFLWQ010000000
VERSION     DAFLWQ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.033"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(287..649)
                     /locus_tag="L1V16_001401"
     CDS             complement(287..649)
                     /locus_tag="L1V16_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275748.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(723..1103)
                     /locus_tag="L1V16_001402"
     CDS             complement(723..1103)
                     /locus_tag="L1V16_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBN1275749.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1167..2360
                     /locus_tag="L1V16_001403"
     CDS             1167..2360
                     /locus_tag="L1V16_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBN1275750.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            complement(2437..3021)
                     /locus_tag="L1V16_001404"
     CDS             complement(2437..3021)
                     /locus_tag="L1V16_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBN1275751.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3222..4220
                     /locus_tag="L1V16_001405"
     CDS             3222..4220
                     /locus_tag="L1V16_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1275752.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4332..4841
                     /locus_tag="L1V16_001406"
     CDS             4332..4841
                     /locus_tag="L1V16_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBN1275753.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(4871..5530)
                     /locus_tag="L1V16_001407"
     CDS             complement(4871..5530)
                     /locus_tag="L1V16_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBN1275754.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5532..6296)
                     /locus_tag="L1V16_001408"
     CDS             complement(5532..6296)
                     /locus_tag="L1V16_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HBN1275755.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6304..6981)
                     /locus_tag="L1V16_001409"
     CDS             complement(6304..6981)
                     /locus_tag="L1V16_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HBN1275756.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7018..8403)
                     /locus_tag="L1V16_001410"
     CDS             complement(7018..8403)
                     /locus_tag="L1V16_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBN1275757.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8613..8697)
                     /gene="ffs"
                     /locus_tag="L1V16_001411"
     ncRNA           complement(8613..8697)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="L1V16_001411"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8720..9235)
                     /gene="tadA"
                     /locus_tag="L1V16_001412"
     CDS             complement(8720..9235)
                     /gene="tadA"
                     /locus_tag="L1V16_001412"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBN1275758.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9342..10199
                     /locus_tag="L1V16_001413"
     CDS             9342..10199
                     /locus_tag="L1V16_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1275759.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10280..10615)
                     /locus_tag="L1V16_001414"
     CDS             complement(10280..10615)
                     /locus_tag="L1V16_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275760.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10682..12052)
                     /locus_tag="L1V16_001415"
     CDS             complement(10682..12052)
                     /locus_tag="L1V16_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBN1275761.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12130..12666)
                     /locus_tag="L1V16_001416"
     CDS             complement(12130..12666)
                     /locus_tag="L1V16_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1275762.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            12975..14456
                     /locus_tag="L1V16_001417"
     CDS             12975..14456
                     /locus_tag="L1V16_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1275763.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLIKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(14559..15266)
                     /locus_tag="L1V16_001418"
     CDS             complement(14559..15266)
                     /locus_tag="L1V16_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBN1275764.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(15345..15683)
                     /locus_tag="L1V16_001419"
     CDS             complement(15345..15683)
                     /locus_tag="L1V16_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBN1275765.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(15794..16756)
                     /locus_tag="L1V16_001420"
     CDS             complement(15794..16756)
                     /locus_tag="L1V16_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBN1275766.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(16771..18102)
                     /locus_tag="L1V16_001421"
     CDS             complement(16771..18102)
                     /locus_tag="L1V16_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBN1275767.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(18110..18790)
                     /locus_tag="L1V16_001422"
     CDS             complement(18110..18790)
                     /locus_tag="L1V16_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBN1275768.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(19009..19488)
                     /locus_tag="L1V16_001423"
     CDS             complement(19009..19488)
                     /locus_tag="L1V16_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HBN1275769.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(19615..21294)
                     /locus_tag="L1V16_001424"
     CDS             complement(19615..21294)
                     /locus_tag="L1V16_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBN1275770.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            21842..23344
                     /locus_tag="L1V16_001425"
     CDS             21842..23344
                     /locus_tag="L1V16_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1275771.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            23357..24019
                     /locus_tag="L1V16_001426"
     CDS             23357..24019
                     /locus_tag="L1V16_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1275772.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(24120..24323)
                     /locus_tag="L1V16_001427"
     CDS             complement(24120..24323)
                     /locus_tag="L1V16_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBN1275773.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(24434..25618)
                     /gene="iadA"
                     /locus_tag="L1V16_001428"
     CDS             complement(24434..25618)
                     /gene="iadA"
                     /locus_tag="L1V16_001428"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBN1275774.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(25775..27514)
                     /gene="yfcC"
                     /locus_tag="L1V16_001429"
     CDS             complement(25775..27514)
                     /gene="yfcC"
                     /locus_tag="L1V16_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBN1275775.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
BASE COUNT         8211 a         5760 c         4670 g         8946 t
ORIGIN      
        1 ttttttaaat tttttagaaa tgtgatataa catccacttc agaatcaacg ctgttaaatt
       61 tatcatgtat ttcttccttg gtcaactata aattaagcat tactttgtga aatgattttt
      121 cgatcaatta ttattattcg ttatacaacc gttttcaaca tattttgaaa ataaaatgca
      181 ctaaaaaact atctttagca gaacatttca ttgtattttt tggaccaaac aataaaaaaa
      241 gaagtttgaa aaaaattcaa acttctttgt tcgcttaatc tgtattttag aagaaaggca
      301 ctccctctac ttcgtaagtt ccaagaacag agcgcatttg acctggttct tcccaaatat
      361 atccttcgcc taattcttct ctttgattct tttgttcagt ttcaaagaca aacaacggaa
      421 cattttcctc tttaatatgt gtatttgtca attccatcaa actaatcttg ctaacatcga
      481 tatgaactat ttcttttaag aaattaagta tattcgctaa accagtcttt ccttcagaaa
      541 gttccgctaa cgcaaattcc aacttgtcat caattgaatg gaccaaaaat tttttagtac
      601 catcctccaa atgcaacata attgtaccag caactctttt gcttgccaaa atttccacct
      661 cgatcaactt gttctatggc ttacataaaa attctagcac attttcagaa aaaatacact
      721 ttttatttct tattttcttt ccgttctagt tcagataatg cttcttctat ccaaataggt
      781 aactgctccg caatagtggt aaatccgatc ttacgatttt tattcgtgaa ataccttttt
      841 ctgcgatatg gaacagctgg atttgttttt tctaacgttc ttaaagataa actgattttt
      901 ttggaatatt catcaatgtc gatgatctga actgttactg gctgtccgac ttttaacaat
      961 gaatggatat ttttcgtata accggattgt acttctgaaa catgaataag tccttgcgtc
     1021 tcgttatcaa gagaaacgaa tgcgccataa ggctgtatcc ctgtcacttt tccttcaatt
     1081 atttgtccaa ttttataagt catctacttc cctctcttcg catttatcat tatactgtaa
     1141 atagctcaaa aaaagaagcg acgaaaatga ctggaggtct taagatgatc gaatttgata
     1201 aacagatttc aagaaaagat acagaaagtg taaaatggga cgcaattgct gagacatatc
     1261 aaatggatga cttacttcct ttgtgggtag cagatatgga cttcttgtct cccggtgggg
     1321 tagctaaagc gtttagtgaa tacatcaaac atggaatctt tggttatgcc actctgtctg
     1381 ataaactata tcaggctatc attcattggg aacgccaaca ccatgctgtg gagttgacga
     1441 aagaaaatat cgtttttaca agtggtgtgt taaccagttt agctgcagca gtacaaactt
     1501 ttacaaaacc aggcgattct attttgattc atgacccagt ttatcctcca ttttcctcta
     1561 ttatagaaac aaatcaacgt cacatcgttc gaagctcttt gctagaaaaa aataatcatt
     1621 tcatcatgga cttgtctgac atggagaaaa aaatcgaaga aaacaatgta aaagcaatga
     1681 ttttatgcaa tcctcacaat cctggagggc gtgtttggag caaagaagaa ttgaaacagt
     1741 taagcgaatt gtgtttaaaa catcaagtga ttctgtttag tgacgagatc catcaagatt
     1801 taactttatt cgatcataca tttacttcca tgctaacgat tgatcctaat ttagatgatc
     1861 tactagttgc ttttacttcc gcaaccaaga ctttcaatct agctgcaatc aaaaattcaa
     1921 tggtatttat caaaaatcca gagatgaaag ctgattttga aaaacattta gtgatgaacc
     1981 aacagcacga aatcaacact tttggactga ttggaaccca agcggcttat gagacgggtg
     2041 gagaatggtt aagccaactg attccttatc tagaaaaaaa tgttcaaaca gttaatcagt
     2101 tttttgaaca gtatcttccg aaagtgagaa taatgaaccc tgaaggaact tacttaatgt
     2161 ggttagattt taccgcctat atttcagacg accaagaatt ggagaacact cttgttcgga
     2221 aaggaaaagt cgtattaaat cctggcatca cgtttggtcc ttccggtcat gggcatatgc
     2281 gcttgaatat tgcttgtcca gaagaaactt tactggaagg acttaatcga atcaagtatg
     2341 ctttagagac aatcgattaa atcatttatt caaaataaaa ggacgagacc ttactaggtt
     2401 tcgtcctttt tcataattac tccgtaccat accaaactat tctgaaattt caattgtttc
     2461 aatcactaca tcatgtacag gtcggtcttg tggaccacgt tgtacatttg cgatttcatc
     2521 tactgtgtcc atcccttcta gtacatgtcc aaagactgta tgtcggaaat ctagccaagg
     2581 agttccgcca cctttatacg cttcaatgat ttctgatggg aatccagcac cttctagttg
     2641 tccaagcata ttagctggca catttgtgtt atttacaata aagaattggc ttccgtttgt
     2701 gtttggacct gaatttgcca tagataaagc tccgcgaagg ttgaacagtt cacgactgaa
     2761 ttcatcttca aaactttcgc cataaatact ttcgccaccc attcctgttc cagttggatc
     2821 gccgccttgg atcatgaaat caggaataac gcggtgaaaa atcacgccat cataataacc
     2881 ttttttggaa agttcaatga aattttgaac cgtcttcggt gctagttcag ggaataattg
     2941 aacagtaatg tcaccacggt ttgttttgat aacagctttt ggtccttttt cactttttaa
     3001 atctagttgt gggaatgcca tattgtttcc tcctaatatt tgcatacttc ataataataa
     3061 taacataata cctaacctct cgtaaaaata ctagatttgt tttcttttat ttttcatcac
     3121 tagatacatt ctataactta ccgtttcgat ttcgaattca aacatttttg agaagcattc
     3181 tcaattaaat tctgatatag tgtgaaaagg gaggaatttt tatggaaatc tatgacatta
     3241 caatcatcgg tgcaggtcct gtagggatgt ttgccgcttt ttacgcagga atgcgccaag
     3301 ctaaaacaaa aatcattgac agtctacctc aacttggtgg tcaattagca actttgtatc
     3361 ccgaaaaata tatttacgat attcctgggt atccagcaat aaaagcaagt gaattaatcg
     3421 atcaattaga aaaacaatta actactttta accatacatt ccatttaaaa gaagaagttc
     3481 tctcgcttac tcgtgaagac gaagttatcg agattactac aaataaaggc atccattatt
     3541 ccaaagcagt cattttagct ttaggaaatg gttcattcca gccaagaaaa ttgaatttag
     3601 ataatgctga atcatttgaa aaccacggat tggattattt cgtgaatgat ttgatgaagt
     3661 atgctggaaa aaaagtcgct attgctggag gtggtgattc tgctatcgat tggacgttga
     3721 tgttagagcc tattgcaagc gaagtttact tgattcatcg tcgcccggaa tttcgtgcgc
     3781 acgaacatag tgtatcacgc ttgaaatctt catctgtcaa cttgcttact ccctatctca
     3841 tcgatggatt atcaggcaat aatggggaac tgacagatat ccggttaaaa aaagtgaaaa
     3901 gtgacgagac gattgatttg atgattgatt ctctgatcgt caattatgga ttctcttcta
     3961 atttagaaca tctttcttct tggggacttg atagtaccag aaatgccatt actgtaaaat
     4021 cagatatgtc tacttctatt ccaggcgttt atgcagctgg tgacatctgt acctatgaag
     4081 gaaaagtgaa actgattgct actgggctcg gtgaagcacc tactgcagtg aacaacgctt
     4141 tacactatat taatccaaag gaacgaactc agcctggtca cagcacaagc ttatacgata
     4201 aaaatcttcg tcctagttga ttttttatat ctctttgcat ttcaagttaa acccgaaagc
     4261 agtttcttgc atttttttca tgttccgtta acatgaaata gagaaagaaa aaataaaggg
     4321 ggagcaataa tatggtcgtc aaaactgaga ctttagaaga aaaggcaaga gaactattga
     4381 aggaacgtgg cgtaactgta gaagatatcg cacaacttgt catgttttta caaaaagact
     4441 atatttctga tttgactttg gcggattgta ctgaaagtgt caacagcgtg ctaacaaagc
     4501 gtgaagtaca taacgccatt atcactggaa tccaattaga tatattagca gaaaagaaaa
     4561 aattgatgag tccgttgcaa catattatcg aagatgacga aggcctttac ggtatcgatg
     4621 agatcctagc cttgtcaatc gtgaatgttt acggtacgat cggctttacg aattatggtt
     4681 atatcgacaa ggtgaaacct ggtattttaa aagaactaaa cagccacgat ggcgttcatg
     4741 tccatacctt cttagatgat atcgtcggag cgatcgccgc tgctgctgcc agtcgattag
     4801 cacacaaaga accagaaaaa agaagtcgcc ttactcaata attcaacaaa aaaagaaaga
     4861 aaacgtctat ttagacgagt tctttctttt ttgtttgttt caagctattt tttcctaaga
     4921 aaagaaaaac agcaaaaaat aattctaata atacaaaaaa taagataaag ctatgcatga
     4981 aaaattcttc tggaagtaca ttgatgattg gatcagtaac gggatcgaat aaccagtcat
     5041 cgttgttgaa aaacgtttca tgaaaaagga taaaaaagcg atcaaatcct atcatcatga
     5101 aaaaaccgaa aacaactggc agtaacatgc cgatttgaaa cggacgaatc aaccgccaaa
     5161 gccgatcatt cttttgcaaa tatttgataa acaaaatact cgggatcaaa gtgatgaaaa
     5221 acacagcata atccactaaa aacaaaattt tcacttcata aaagtgatgg gctccgctag
     5281 cagaaactgg gaaatctggc aagctgagga tggttttgaa gggattattg agataattca
     5341 ttaggtgatc aaaatttttc agtaacgtct cttgatctaa agaagtataa tccaaaattt
     5401 gcaaatgtcc gatatcaaat acgtatagtg gtcgaaagtt gatcgtcaca ccaactgcca
     5461 gactgatcag tgtcagaaat aggctgaaca atccagcata ttccatccac tgccatctcg
     5521 aatttttcat attagaagct ccattcatcc agtgattgtt tcacataggt agctgggata
     5581 ggcaacccag gtacatcttc ttcttttgta aaacctgata aaacgagcaa agtatctata
     5641 ttattgcgta tcccagcttg gatatctgtt tcatagttat ctccaaccat gattacttct
     5701 tctttttgca gccctaatac ttcaacggct ttatccataa tgatggcttc tggttttccg
     5761 atgtagatcg gcggcgtttg ggttgctgtc tctacaaaag agatgactga ccctgctcca
     5821 ggaagaaggc cgcgttcagt aggtatattc ttatctgggt tcgttccaat gaaagtagca
     5881 cctttttgaa tagcaagtgt tgctttaact actttttcat aggtcagata attatctaag
     5941 cctaccacta catagtcagg agcctcttct tcccatgtaa atccggcagc taaaatcaag
     6001 tcaatcaatc ctgcttctcc gataacatag acttttttcc cttttccatc tgctttcata
     6061 aaatcgattg ttgccaaagt agctgtgtag actgtctctg gagctacatg aatgtcaaac
     6121 tcatctgcta gacgattagc tactgtttct ggtgacttag tcgtgttatt ggtaacaaac
     6181 aagaaaggta attttctttt ttgcaattct tccacaaatc gtttaccggc cggtatgggt
     6241 tgtgtcccac gataaatcgt tccgtctaaa tcaattaaat atcctttata gtccattcat
     6301 ccactactct tccctttttc tgatcgtaaa tgctgttttt gttttttcta cttgtttagg
     6361 ttgttcttgt ttttttactt tttcagaggt ttttgctgac tctgtttttc gatttttaat
     6421 aaccggtttt ttgcgattag atgcgactgg tccttttttc tcatcgatat acgcacgatt
     6481 atggtttttt ttcttttttc ggcgctgagt tgtcttttct tttttaccgc cgattctctc
     6541 gatgacaaaa tacgcacaac caaaattgca atattcgtaa agatagtctt ccaaggaatc
     6601 gattcgctga tctggatgcg cccgtcgatt atccgcttgg aaaaatcctt ttaggcgtag
     6661 ttgttcataa ccccaatctc ctacgatata atcatatcgg gctagtacat cactgtaacg
     6721 ttctccaagc ttttctgcat taaatccttc acgataatcg gacacaagcc gataatgtct
     6781 ttcacctatc aaaaaattac tgtcatctaa cagtgtcact agctcgcctt tgactttttc
     6841 tgctttaggc tcctcaacga tttcttccaa agcagctgtc agttcttcgg tgactgttgt
     6901 ttcctgttca gctgatgatt ttttcttagc aatttctgtt ttatgctcaa cgttctgctg
     6961 ttcattttgt tttgcagaca tgcgttcacc acctatcttt tttattatac cttgttttta
     7021 tttgattggg tagtgagctt tcaagtaatc tcctaccaca cttcggataa attcagggaa
     7081 caaaaattca ttttttccag caatctcaat cgttggaaaa aatggaacaa acatcaaatg
     7141 atctacggta gtaaaagtat aatttttatt cagatcgatt ggcttgttct tccaaaagac
     7201 ttgatggtta atagaatcat atgtgattcc attatagacc atctgcccaa aaatcttacc
     7261 gcgaaatccc attcccttca taggatagtt acgtaaaaag ttacgatttt tttctatttc
     7321 taaaactaag cggatcagat catttccacc caatgtgaca tttaacaagt gcatcggatg
     7381 cggcaacgca gtgtgaagct gatcctgatt gacccgccct tttggaattt cagttaaaaa
     7441 cagaccactg tttaatattg ctgcttccgt ctttcctcgt tctttcaccg cctcaaaggc
     7501 tacttggata aacgaatgct cattgaagat atctagactc agagaaaatg gcaaatctgc
     7561 tacttctttt tcttttaata attcatgccc acgttctaga taactattta tttcttgttc
     7621 atcttctgta aaagctgtca ttgtttcggt agggatggct ttggctgaat gcttaaggat
     7681 ttttttctct tcatcgatgg ttaaatggac ttcaccgaca tactgcccgt actttccagc
     7741 ggctgctatt tggacatcat tgattacgtg accttctctg aataaatgat gggtgtgcga
     7801 tcctaaaata acatcaattg ctggtatttc ttttgcaatt tggaaatcat cctgaatccc
     7861 gagatgactc atcaaaacta aaacatccac ttgtgaacgt aaatcttcga ctaattctgg
     7921 caaaatatca taaggattcc gtatgtccca gccattcgga ttataagtaa gcggaaatgg
     7981 agcagtaaat gcaattagtc cgattttcgt ctggtgtttc gttgtaatga ttttatatgg
     8041 tttcgtccat gccggtggct ggagcgtatt tttatcgaat aagttatcca ggatgatatc
     8101 aaactcagca tgatcgtata aatgattcaa ctcttctttg gaatttccta cgccttcatt
     8161 gtttcctatc gtcgctgcat cataaccaac ttcattcatc agcaagatat tttcctgtcc
     8221 attcgttgct tctgacaatg gatgccaacg atccacaaaa tcacctagat ctactgcaat
     8281 cgttgtcgtt ttttctttct tttcgttttc tcgtttacgt tgatccaaaa accttctgat
     8341 ccttggccaa ttttctaaat gagaatgcag atcattcgta tgtaaaatca ctattttttc
     8401 catgtaccct ctcgcctctc tttatcttta tcataccata ggcagctttt tcttccattg
     8461 aaacaagctc tatttcagag tttttcctgc cttgaagcaa attgtataag tacaatattc
     8521 gataaatcag tctggctaaa aaatcaggaa cattcatttt tacagtacta taaaaataaa
     8581 aaaaacagac ccgaaagtct gttgtcgttt cattataatc agacacatgg cggaacctgc
     8641 ttagtgctgc ttccttccag acctgacacg cttcacaagc ccaccattgt cctagccttt
     8701 cggcaaagaa tagtatacct tatttttcat tcgttgacca gtcttttttt aatttctttt
     8761 ttcgctggcg gagctttcgg aaaaagtcag tcaaaatcat cccacattcg tcttctaaaa
     8821 tgccaccttc tacatatgct tggtggttaa accgctcgtc ctccaaaaga ttcatcaagg
     8881 taccggctgt tccgcctttt ggatcatacg cgccgaaata aacttctgct acacgagaca
     8941 aaatcatcgc gccgctgcac ataggacaag gctctaaggt aacaaaaagt gcagcatctt
     9001 ccaagcgcca gcttcccact ttttcacagg cttccttgat tgcaagcatt tctgcatgtg
     9061 tagtagcatc ttgcgtggtt tctctaaggt tatatcctct tccaatcact tttccatcca
     9121 atacaaccac tgctccaatc ggaacttcat gaagcatttc tgctttcttt gcttctgcca
     9181 atgcaaggcg catccatttt tctttttcta ctgcatcaag atttgtattt accaattacc
     9241 cttccctgcc tttgtttttt cttgttttac tttagcatat gataaaaagg ctgtaactaa
     9301 cttttttttc tatggtaaaa taaatacaag aggtgaacaa gatgaaaatg gataaattac
     9361 ttgctcttta cccacaagca cagaaaaaaa actctccagc atcagaagcg gatatccttt
     9421 cttttgcaat tgatgatgct tttatctgga tcaaacaaga ttcattatct caacaagaaa
     9481 ccagcctttt gaaagcgtta ttccctgtaa tcaacgatca aaaaaaacac ccatggtatc
     9541 actatctttt taaagatgct tcttgtgttc aagaaaaaag ctttcgtttg atccagcttc
     9601 acgtcgaatc aaaaggagaa ttcttaaaaa aagaatggca agatactatt ttggaattat
     9661 ttcgctattc tgctgatttc tttttttata cagacacaga tgcgctctta gtcgaacaaa
     9721 taaaccgtga ttatcttgat gctactgaaa tcaacggtat ttttctatct ttagatgctg
     9781 attttgatac gacaacgtct gtattcgttg gttctttcca ttcacctggc accgacctcg
     9841 tccctttgtt tgctgaagaa agaaaaattt ttttaacaga gcaaaacaat ctttatactc
     9901 acagccgtac tttttctatg caagatgtgg ctttacatta ctatacaaaa gatactgtaa
     9961 aagatagtaa gttgatcaaa agttacatag aactgatcaa acaaaatgaa atggaagtga
    10021 tcattcaaga attatggaat gaattaggca atgtcagctc tgctgcaaaa acactgtttc
    10081 ttcatcgtaa tactctaaaa tatcgaatcg aaaaatttca agaacagtct ggtttcaatc
    10141 taaaaaaagc caacgattta ctgttttgct atcttttatt gcttcatgaa cataattaaa
    10201 gatagattaa aggggttgtg acaataattt tgtcacaacc ccttatttcg aatgaatagt
    10261 gttcaaaagc tagtttctct tacatcattt tttcaacaaa atgcattagc cggtctttta
    10321 catcttcggt tgaatctttg attgaatcac cataaacaga gattttcttt tttcctgatt
    10381 tgatttttgc taacattccc atcaaagaat ccaagtcact atctgaaaga ccatctacga
    10441 tttctagtaa tttttcattt ccatcaaatt tgtcatagac gaattttttt actttcgtcc
    10501 gagtagtcat atgatggatc ttttccatta cttttcccga tacaacgact gctgtcgcta
    10561 cactggcagc ggctgctacg cttaatccga ttgttacttt tgttgatgtt ttcataagta
    10621 tcagctcctt tttatctatc tccatcatag catagacaaa aaaataaacg aactaatcca
    10681 ctcagtgaaa tctcaatcct ttagggaaaa agttctttac tgttcctttt acttgtttcc
    10741 caaatccgac aggtatctta tctaatacta gcaaaaccca tccttgattc ccatcacgtt
    10801 gaaatgtttc tcctgctgtg taagattgcc attccttttg agtgatcggc aagcaaggta
    10861 tattctctat cttttttgta gcaagcgcta atgcatagct aggttcaaat cgattctttt
    10921 tgaaatctcc taaatgcaaa cctgtacgta cgacttttaa accatcgaga gaaggggcta
    10981 actcaggaac ttcccaaaga tggtcgttga acactaaaag tcttccagta gcttcataat
    11041 gaaaatcatt tgaaaactcc gtccagagtt tttcctgctc ttttgtcatt tgcactttac
    11101 ttttttttcg tgtcttcttt tctttatgca tctgattttg tccatgaaaa gtcagctttg
    11161 caacaaaatg tccttcaccc tgatctttat gaggccatat acgtattgtt ttttccaaac
    11221 cagctacgct tccccattca gaacgtcctg aactaacgga ttgagtcaaa ggaatctcct
    11281 caatcgttac tggataattt tctacaagcc agctaatgat ctcttcattt tcttctggtg
    11341 caaacgtaca agtcgaataa atcagttgtc ctttattttt tagcattttt attgctgaag
    11401 acaaaatctc ttgctgacgt ttttgacagt atagcggaga ttcttctgtc cactctttta
    11461 ttgcatttgg atcttttcgg aacattcctt ctcctgaaca aggagcatca accacgatcc
    11521 gatcaaaaaa gcccgaaaaa tgagggacaa gttctgcggg tgcatgattt gtcactattg
    11581 cgttcgaaac tccccatcgt tctatatttt ctgataaaat cttcgcacgt ttcggaaaga
    11641 tctcattcgt cactaataac cctttcccct tcatttgagc agctaattgg gttgatttac
    11701 caccgggagc cgcacacaaa tccaaaactt tttcaccggg ttttgctgca gcagctgttc
    11761 caacgatcat tgcacttggt tcttggctat attcataccc agcttgatgg aggaaagact
    11821 ttccattgac agtgccaaga aatccctcat tgctgtaggg agcgggttgt aattcttcgc
    11881 tatggtaagt ttggaccatg tccaatcctg ccggttttag tggattccac cgaaatcctt
    11941 ttttcacgct tccttgttca agcgcagaaa aaaaatcgga tgcttcttcg cctaaaagaa
    12001 gacgatattt tttgataaat tgctgtggta acgttgtcgc ttcctccttc attccaatgt
    12061 ttcgttagac attttacaat cttttttacg aaaaataaag gtggctgatc tactttttca
    12121 tgttgctgcc taaggtgact gttcctttaa gatattttcc aagtattcat ccgtcacctc
    12181 gtttttatcc caaacagcgt tcatcatttc aagaaaatct tgagaagaat catctgagcg
    12241 caaacttccc aatgcattaa gccataccaa ttcaagcgac ttttcttctt tgatcttcgt
    12301 gtgacctttg acatatgaga aaaatggccg cttaaatagc gaatccatgt ctaaatcaga
    12361 ttttgcaatg atttcacgaa tactttcatg gatagaaaaa aaatctttca ataagtagac
    12421 aatgcttaaa acatcatcgg aactgcattc agctaagtag ttttcaaaat aaacagtgat
    12481 ttcttctaat atcttctctt ttaacccgct gattgatttg aaatgtgtat aaatcgggta
    12541 tgtagaacaa ccgcagaact ctgctaactc tcttgcagta attgacttca ttccatattc
    12601 ttccacgtat accatacttt tgaacagcaa atattcttta ctataatttg ttactctccc
    12661 catcattctt acctccgtct cttttcatct acccataaat aaataacata aataattcta
    12721 aaaatattat tgataattat caaaacatat ttagttatat ccattaaaaa tcaatttttc
    12781 cgccttaaaa acaagaatat cttgacaaaa taccctagga aataaacaat agaataaaca
    12841 aggtaacaaa aaaattaaat aacgttatat aaaaaagaag gcgacactct gtgagaataa
    12901 cacagactga aatgactttc cactcacagt ttttgtctaa ctatatacaa aaacagaata
    12961 aaaaggaggt atttatgcta attgaagcaa gaaaaaaaga gttacttgtt ctacaaatgg
    13021 tcattcaaaa aaataattgt tctttacaag aattatccaa tgacttacat attccaaaac
    13081 ggacaatcaa agaactgatc cgaaaaataa atgtatcact caagcaattt ttattgattg
    13141 atgaatttat ttattctaat cataaaggag agatccaaac caaagaaacc gatcaaacta
    13201 aaaagttagc tgttttttct aagttaaaat tatgctacct aaaagaatcc aatcgtttta
    13261 actatttgat gttactaatc aattatccac aaactgctgt accaaaaaaa tatttacttg
    13321 aacaacttta tatatcgccc tcctatctcg aaaaactgac aaaacagctc aatcattcct
    13381 taataaaatt ccatttacgg atcctatctg taaaaaattg ctgtactctt gaaggaaatg
    13441 agttatctat ccgtctctat ctttactttt ttctttcaga tacatttgga ggtaacgatt
    13501 ggccattttc ctcacttgaa ttaaatgcac taaaaatgaa cagtacagat gagcaaatag
    13561 aaaaaatttc aaaacaagaa aaaaatatct acttgctgtt aactttattc atattacgaa
    13621 acaaacaaca ggcatatttt ccaaaaactt cttctgaaat cactgaattg atggacttat
    13681 tgcagcatac acatgattat tcagaatact ttacttcttt ttcagtgagt cgcccttgtg
    13741 aagagacaga aacagagaga gcctacttta attatttttt ctattgtttt tttccaaatc
    13801 aaatctcttt tcgacaaaaa caggagattg gttttttatt ttccacaagc aaaaacctta
    13861 tttgtcgaca agtcggtcaa ttgatgactt acttaactca acagtttcct ctcaaccatt
    13921 tagaaaataa aataccaatt tatttttatt ttcttgtgtt ggcagttgtt tttttcgaac
    13981 tgttgggtga atccagcagt agtttttcta cactttgctt tccagaagcc acgtccaatc
    14041 attctagttc ttttatacag gaaaagaaat taagagaaaa aatcgataca attttttcaa
    14101 aaaatgggga aagaaaccaa atcagtcaat accttagtca attgatccaa cacttactac
    14161 aaacagaaac gaaagagcag ttactcatcc atttgcagat aaccaaacag tttacaggaa
    14221 attatcatct tcaaagccat ttgcagcagt tatttcgcaa agatgctgtt aaaattaccg
    14281 catattcaga acatgctgat ttgatcatta cagatcagca tgagaaaatt tcagatgaaa
    14341 cggagacttt ctatctggat acaacgcaca atacagtgtt atttggcaag ttaataaaag
    14401 cggttcatga actgtatatg aaaaaaggtt atgagaacaa aacaaagagg atgtgacaaa
    14461 attcttgtca catcctctta ttccaaataa atggtattca atcagctaac tctcggtatt
    14521 agctcagatc aaagcgctga tttcacaact tctttatttt aatctcttcg gttgccgccg
    14581 aacaataaga tcaagcgcaa cagctgcagg aatgtcgaaa gcgctgctgc aacataagtc
    14641 agtgctgctg caaataatac gtgtcttgcc atcggtactt cttcttccgt cagtagtccg
    14701 ccttcactca aaatttggat tgctcgccga gacgcgttaa attcgactgg taatgtcacc
    14761 aattggaaaa gtaatgctaa agaaaaagcg aaaatcccga tattgattaa cgtagagttc
    14821 cagctaagca atacacctac cataatcaag gggaacgaaa tcatcgaacc aaagttagct
    14881 gctggaacaa gtgctgcacg aatcttcaat gggacataac ccgaagcatc ttgtaccgca
    14941 tgtccgcatt catgagctgc tacacctatc gcagcaactg aagtagactg tgcagttgct
    15001 tgagacaaac tcaacatctt attacctgaa ttgtagttat ctgtgagatc tccggcaatt
    15061 tgttgaacac cgacattatt tatctgttga ctttgtaata tatattgtgc tgcttgtgta
    15121 ccagtcacat tgtttttgct tctcacttga tcgtattttc ggaaagtact attgacgtac
    15181 gctgacgcaa ttccggaaat aactaatcca agaatgacca aaagaaatgt cggatctaaa
    15241 aaaccataca ttccataacc atacattttc gtttcactcc ttttcgttta ctttatttta
    15301 tcattagtag taggaaaaga atgtgaaaag accttgaata ttctttaatt ctttttcaca
    15361 aattccgatt tcagtttcat cggtccaaat ccttctacct tgcaatcgat attatgatcg
    15421 ccttctacta aacggatgtt cttgactttt gttccttgtt taatggcacc tgacgcacct
    15481 tttactttca agtctttaat cactgtcacg ctatcgccct ctaacagacg gtttccattt
    15541 gcatctaata ccactaatcc gtcttctatg acagtttctt gttcttcttt gttccattcg
    15601 ttcccgcatt ctgggcaaat caacaagcct cgatcttcat atgtgtactc tgagccacat
    15661 tctgggcaat ttggtaatgt catcttcttt ctcctttaaa atctttagtg agcactattg
    15721 taacggaaaa agaagatctt gaaaagatac atttgtgatt tttactacaa aaggcacgtt
    15781 ttcgaacgaa gtatcattct gtttttctgc tcttatacga ttggcatata tcttggatct
    15841 ctttatagat ttcctctact tctgctaaat cttttgcatt cgcaccactt gctaatggat
    15901 ggcctcctcc atgatggcgt ttagccaatt cattgatgat cggcccctta gaacgtaaac
    15961 gtacgcggta ataccctgaa ggctgctgaa caaaaatccc ccaagccagc acttcgtcaa
    16021 tcactccagg aagtgaaacg atcgaagctg tctctgaatc atcgattcca tatttatcaa
    16081 gaatttcttg cggaaggatt attcttcctg caccattttc atccacctgg atattttgat
    16141 aaagataacc ggaaagttta gcgactttca tcggcatttg ttcaatctct ctgttcaaag
    16201 cacttgcatc aaatggataa tttctcaata tcgaagcaat ctctaatgta cgggacgtcg
    16261 tggagggata caaaaagcgc cctgtatctc cgacgattcc tgcataaagt aaccgtgcag
    16321 ccttaacgtt catctttaaa gattcaggaa acatcaaagc aaattctgca atcatctcac
    16381 tacagctact tgcttttgta tttacccaca caagatctcc ataagggtca tcattgggat
    16441 gatggtcgat tttgatcagt ttttctgcca actgatatct ttgatcactg attctgggtg
    16501 aattagctgt atcagtcacg atgactagcg ctccttggta gaagacatct tcaacttctt
    16561 gcatttctgc taaaaagcga agcccttcaa tcgtttcacc tacttgacgt atttcttttt
    16621 ctgggaaact ttcccgtaat agttcggcta atcctacttg tgatcctaat gcatcaggat
    16681 cagggcgcaa atgcctgtgg ataatgattt tatcgtattt ttttattgta tctactattt
    16741 cttgctgtac tgtcatttca ctcctgcttt ctaagaacgt tccattactt gacaaacaac
    16801 gattgctttg gaaacgatgg tgttttcaat aaacacttcg atatccagtt tagcggaacg
    16861 tctgccgatt tccaatacac gtggacgaat gtctaattcg ctttccaatt ggatcagccg
    16921 caaataatgt aggttcactt gttcaatcaa gatatttcgt ttttggttca tcaccattgt
    16981 tttttgtgcg acatcagaaa tgatttcgct aagtacgcca aaagaaatgg ttccaacgcc
    17041 attgaccatt tgtggtgcta ctacgaattt gaacttaggg ttttccaaac gatttccttc
    17101 acggtcagta tcaatcgtat ggatatttcc agatatctga tccgaaatcg tatctgcaat
    17161 ctgcggttgt cgctggacaa gctgcatcgc tttcattaca tcttgccggg taatcaagcc
    17221 ttccaatgtc aagtcatcgg aaacgaccgg catgacttct agcccatccc agatcatttg
    17281 atggctaaca gaggcaatac tcattgtttt ctttacactg attggttctt tcgtcatcac
    17341 ccgatcgatg atctggtttg gcgatttccc taaaacatct tttgccgtaa caatccccat
    17401 caaacgatga tggcggttga cgactggaaa acgcgaatgc tgcgtttctt ctgacaaacg
    17461 ctgataatca gaaatcgtat ctgtctgctg caaataatga gtcttttcag ctggcatata
    17521 gatatcactg acaagcatga tatctttttt gatcaattgg tcgcttaacg ctcggttgat
    17581 catggttgcg actgtaaatg tatcataaga ggtgcgtaag atcggcattt caagatcatc
    17641 agctagcttt gcaatctcag cagtcgtatt gaatcctcct gtgatcaata ctgcggcgcc
    17701 atcttccaat gctaattttt ggacttccgc ccggttgccg acgatcatta gtgatcctgg
    17761 cgtaatatag cgttccatgg catgtttagt catcgcgccg atgacgaatt tattcaagac
    17821 cttgtctaat cctgccgccc cgcctaaaac gtccccttca atgatcctga cgacctcgcc
    17881 aaatgtcaaa cgttcaatat gtttttttaa tttgcgttcg atacggatgg tccctactcg
    17941 ttgaattgtt gaaactagtc cgacattttc tgcatctttg attgcacggt acgctgttcc
    18001 ttcactgaca ttcaattctt ttgcgatgct tcttacagaa attcgattgc caacaggtaa
    18061 actttcaata tattctaaaa tcaaatcatg ttttgtcgcc attttctgcc tacacttcca
    18121 gcgtttccga gacgctcatt atttttcctt cactatcttc cagtaactct acaaaagatt
    18181 cgggatcttg ttcaatgaca gggaaagtat tgtaatggat tggaactact ttcttggcac
    18241 gaattgtttg cgcagccttt gctgcatctt ctggccccat cgtatagtta tcgccaatcg
    18301 gcaagaaagc gacatcaata tcgaattctt ctgcaagcaa tcctagatca ctgaaataag
    18361 cagtatcccc tgcatgataa atcgtttttc cttctgcttg aataataatt ccgctaggct
    18421 cgcccatata ctgaacgata ccgtctactt catagcttga actatgctgt gcatgtacga
    18481 attttaccac gccgaatgga aacgcatgtt ttccaccgat attcataccg aatgaatcta
    18541 ctcctctgct gttcgcataa tcagcaatct caacaatact gataattgtg gcttgatttt
    18601 cttttgcaat aggaatcata tctcctatgt ggtcactatg accatgagta atcagcaacc
    18661 aatctgtctt tacttcttct gcagttaagt ctgtcaatgg atttcctgta ataaacgggt
    18721 caatcatcac gcgttggcca ttttccattt caattgttaa acaggaatgt ccatgatacg
    18781 taattttcat attttacacc tcgcgttttc tctgtatctt ttttattaaa aacgatttca
    18841 tcacttgcac atcaatgaaa aaatatagct gctaaatata ttttcattgg attgatagta
    18901 cagtatgtac aaagcaattg taacagataa tacaggatgc accaagtacc aagcagatat
    18961 aatctcaagt ttgaggtctc tgctctgctt agcttctctt ctcgtccctt aactaattaa
    19021 atcagcgtaa ataggatgga cgatcttttc taaatcggct acttttatcc gaaggcttct
    19081 cccgatttca ccgcttgaca caattacttc ttctttttct tttaaagaac tgtctgctaa
    19141 aaaacaataa tcaggatgtg cgagttttat tccaataggg gtgtttgctc cgtggggata
    19201 tcctgtatgc attaatacaa aatccattcc aggaaaacca actttacgat ctttcgtcac
    19261 ttgtctcgtt tttttgtaat ctaagtgatc gttcaaagga atcaatgcga tgatcacccc
    19321 agttttgttt cctttcacta cgagagtttt acatatcaaa gctggatcaa tccctctttt
    19381 ttgtagttct tctgtgaaag attcttctac cacatgacta aaatcaagtg gttgatagct
    19441 gatcttttgt tcttctaaat aacgttcgac ttttgtttga ctcatcattg attcactccc
    19501 tttattctat cgtttattat aaagcgaggg atgctgtatt caaaaattat ttgtttttcg
    19561 caaaaaaaga gcaagacgag cactctatag agaggttcat cttactcttt ttgtttattt
    19621 tttatttcga cgttgagtag cttccataat gactggcaag atcactgggc ggcgttttgt
    19681 ttgttcaaat aagtaacggc ctaattgatc tcggatgtct tgctttaatt tgctccactc
    19741 aaaatcattg ctttctaaat gtttctcaac gattgtttca atcatattgc tgctttcttt
    19801 catcagatca cggctagctt ttacgtaaac gaatccccgt gaagtaattt gaggttttga
    19861 aatgattttc ttttctcgcc gactgatagt gacaaccgct acgaaaatcc cgtcttctga
    19921 caagattttt cgatcacgta aaacaatgtt tccgatatca cctatgccta atccatcaat
    19981 cattacattt tctgcacttg tagttcctgc aacactcata cgcttgttct tatattccag
    20041 cacgtctccg cgtccagtaa tatagatatt tttgtatggc atccctactg catgagccaa
    20101 atctgcatga gcagctaatt cacgatactc tccttgaact ggcacaaaat atgttggttt
    20161 catcaaattg atcattaatt gcaagtcatt aggattggca tggccagaaa cgcgcatatt
    20221 ctcagagatc aacttcactg ttccaccagc tcgataaatg atatcttccg ttttcgccac
    20281 gatggtttcc atcgcgatgc ttggcgtagt agtgatataa accaaatctc cttcttcaat
    20341 cttgacatta cggtgtgtac cgtttgccat tttttgcaga gacttgatgg gttcacccat
    20401 tcggccagtt tctaaaatga tcagttcttc tggatcatag tttttcatgt ctttcaacgt
    20461 aacaagcaga tcttcacttg gtaattgaag tttttctaaa cgcatcgctg tgcgaataat
    20521 tcgttcgaaa tcttgaccag tcaagacaac ttttcgttgt gctttttctg ctgcatccaa
    20581 tacttgttgc actcgttgca aattacttgc tacacaagcg acgatgatac gcccttccca
    20641 atatttgatc gtatcaaata cttcatctgc tatttgggct tcagaagcta caggctgagg
    20701 attttctgca tttgccgatt cacttagtaa ggctaagact ccttctttgc cgatttccgc
    20761 caatcgtgca taatctgttt gatacattgg gatagccgtt tggtcaaatt taaaatctcc
    20821 cgtataaacg atactacctt cttttgtttt cagattgatc cccactgaat ctggtatcgt
    20881 atgagtggta cggaaaaagc tcactactgt ttcaccaaag tctatttctg tatgctcatc
    20941 taccacatgg aaatccttaa atcctttggc tgcttcatta cgactgacat tcaattttgc
    21001 taactcgatc gtcaactctg tcccgaatac tggtacagaa atttttgaca acaagtaagg
    21061 aagtgccccg atcgcatctg catgtccatg tgttaaaaag acaccagcta cacgatcaat
    21121 gttttcttct aaatacgtaa aatcagggat tacgacgtcg atccccaaca actcattttc
    21181 aggatatttt agcccacaat ctaaaataaa aatatcctcg cccacttctg cgacatacat
    21241 gttttttcca ttttcacgaa cgccgcctaa tgggataatt ttaatggtac tcacaaactt
    21301 cacctcttct tatgacatcc aagtttaaag atgtcgattt tcttctttat ctaaatatat
    21361 gagccattcc aatgaagcat atgcaaaatc actatttctc aacttatgga gaatcagcag
    21421 gaaaattacc agcacatccg cgttctgaca gttggatggg cattttattt tggatatact
    21481 tcattaacaa aatggatctt ttgcgaaacg ctatagccag aatacttata taagtattca
    21541 gctgttcccc attattatac aacaaataaa ctaaatcgct agtatcagca attgttagaa
    21601 caactatgca cgtaaaaatc cctctgtagc atctaggatt tcttttgcta ttcctctttc
    21661 atttcttctt cgtcggtttg aaacatactt ttttcatttt accacatttt ttgcaataac
    21721 tatagtgact ttttatatat acagaacctc atgttgatgg tgtgcaaaca gcataagatt
    21781 taagctagct ttaagatagg ttgtctatta tcaaatgcat ctactaggag ggatgcaaaa
    21841 tatgaatttt atgaaacgtg catggaaaag tacaaaagta aaatggggac gttcattgtt
    21901 attgtttgcc gtgttcacag ccattcttat ttttgtgcta gctggcctca cgattcgaag
    21961 cgctgcagaa gaagcagcga atcaagcaca aaaagaagtt ggagcaacag tgactttaag
    22021 tgccaatcga gaagcttcat ttaaaaaaca ggaacaaact tcttcaagcg gttctaccac
    22081 tgaagaacgt ccagatccag gcagtttttc tcttacacca gtttccttaa cggacgcgga
    22141 aaaaatagct gaattagata atgtaaagag ttattccttt gaaagttccg cctcagctat
    22201 ggcaaaagat ggaataactg ccatcactag ttctgattca agtgaagaca gttcagaaac
    22261 tactgatgca ggcggtgaac ctgctggagg aatgggcggg aatccgcaaa tgactcaagc
    22321 agactttcaa atcagtggtg tgtcagcaac tgcacaaaat agtaattttt ctgatggaac
    22381 agcaaaaatc acggatggtg aaggaataga tgacagcgac aaaggcacaa acaatgtagt
    22441 cattgattct actctagcag aaacaaatga cctggcagtc ggagatactt tcacaatcac
    22501 gagtactgaa gatgaagata ccacttatga aatgacgatc aaaggaattt atgaatccag
    22561 cgaaacaagc ggcagtatgg gtatgaaatt caacttcatg aatccgtcga atacacttta
    22621 cacttcttac acttttgcaa atgaactaaa tgggacatct gacgataaca cgatagattc
    22681 tgctatttac actctatctg atccagataa aatggatgag tttctcaaag aagctgagaa
    22741 gctgatcgac acagatacat ttagcttaca atcaaatgat tccatgtatc agtcaatgtt
    22801 ggaaccttta aacaacgtgg caagtttttc taaaaatgtt gttttactag tggctgtagc
    22861 cggtattatc atacttactc tgatcattat gattaccatt cgggagcgtc ggcatgagtt
    22921 aggcgtcttg ctatctttag gagaatccag aagtaaaatc attctccaat tgtttaccga
    22981 agtggctatt tgtatgattc ttgcattagg agttgcttcg cttagcggaa acgtcgtcgc
    23041 gaatgccgtg ggacagcagc tacttgacca acagacagaa accacgacac aaaaccagca
    23101 agctcctggc ggtggacaaa tgccaggtaa cagacaagaa caaggcggtc aacgcgatgg
    23161 tcaacaagga accacgaata atccatttgc tgtttctgat caagtcagcg aattggaaat
    23221 caatgtcaaa cctgcacaat tgggactatt agccggagta gcatttggaa tcagtctgtt
    23281 ttctgtcttt ttagcttcta tagggatatt aagattaaac ccaagaaaaa tcctattaaa
    23341 ctaaaggagg aatttgatgt tacggacaga acaattggga ttttggtatc aagatccgca
    23401 agatgcgctt tataaagatg tagaactgaa tttcgaagct ggaaaaatgt acgctatttt
    23461 aggagcaagt ggttctggaa aaacgacttt tctttcgctt atttctggac tagatgcacc
    23521 aaaagaagga aaggtatact atcaagatcg ttcactgaac aaaatcgggt taagaagtta
    23581 tcgtaaaaat gatgtctcga ttattttcca agcttacaac ttgcttcctt atttatcggc
    23641 tctagacaac gtcatagcag caatggaaat cactaagacc aagcaagaga attatcgaca
    23701 agttgcttta gatcgactgg ctcgtgtagg aattgatgaa atattagcaa aaaaacaggt
    23761 gaccaaactt tcgggaggtc agcagcagcg agtcgctatc gttcgtgcta tctgctgtga
    23821 acatcaacta atcgtagcgg atgagcctac tggaaatcta gatgaaacaa cttcacaaga
    23881 tatcgtcaaa cttttccaag aaatcgccca tgaacaaaat cgctgtatta tcatcgtgac
    23941 tcatgagatt gaagtagcaa aaagctgtga tgaagtcttt gaactaaaaa ataaaaaatt
    24001 tcaaaaaatc gaagtttaaa aaacaggata atgatcaaat aaaaaatccg aaccatatct
    24061 gtctcgcaga tatggttcgg attttttatt tgcttgattc aattagtaat aagtggtttt
    24121 tatttttttt cgtcttttcg agaaaacttg tctttgactt cgtcgcctaa atttcgagct
    24181 ttttctttga tgtcagcacc tagtgattgt gctttccctt ctgtttcttt gctcttgtcg
    24241 tctgttgctt tgccgtatgc ttcttttcct tcaccgacta ctttatcttt catatcttta
    24301 gaacgtcctt ttaaatctgc cattgtgctt cctcctctta gtttgtttat tgatctacct
    24361 tcagggtaac atcaacaaca gatacagaca aacagaacgc tcgttttcta aaaaagatag
    24421 ttagagctgt tgattaaaaa cttttttcga aagtccccca tactttgact tctttttctt
    24481 ggaccattat ttctccttta gcgataactg tatcaatatc aagcgtttct ttatccaaga
    24541 tacacagatc tgcatcagca ccaatttcga tttttccttt tttatccaat ttcaatatac
    24601 gtgctggatt actggttata gctcgtaagg cgatttccaa agggatactt tctttttgca
    24661 cagcttcttt gatccctact agcaatgcct tggcacttcc tactcctaac cctaggaaat
    24721 gattgttttc atcaaaataa ggcaagcttc cttgtccatc tgaggtcatc gtgaaattat
    24781 ctaaagaaac atcttcctcg atcaatcgtt tcagtgcttt gctgaagcga acttcaccat
    24841 ctgtcttctc ccaaaaatca ggatcttcgc tagcagtgaa gtcaatcgtg ccaccacgtt
    24901 tggcaaatgc cacgcaagct tcaaataatt ctggtgtgcg atttgcatga gtaggcaaaa
    24961 attgtgtgat cggaatttct gtttcttcta cgattcgtgt caatagctct agctttcttt
    25021 ttcctccgcc taagtggaca ttgatgatcc cagcttttcc ggataacatg cctcctacac
    25081 gagcatctgc tactgcacga gcgaactctt caaaacttgg ctgagaagaa cggtgatcgg
    25141 atactgcgat ttctccgatt ccgataattt tatcaattgt caaaaagtct ttgatgatag
    25201 aatctgttac tgtttttacc ggcaatcggt acgaaccttc gtatacataa gtggagattc
    25261 cttctgcttc cagacctttc gctttgctga tcaacgcagt catatctcta ccttctccgt
    25321 ctgttcccaa acaaccgaca actgtcgtta caccagctgt agtcaattgg ctcaatgtga
    25381 cttctggcgt tcgattttga taaccgcctt ctcctcctcc acctaaaata tggaaatgac
    25441 agtcaatgaa acccggggtt agtacttttc cctcacctga aagttcttct acttccactc
    25501 cttcgtagcc gccttctagc tgttcttcta cagccaaaat cttcccaccg gcaatcagta
    25561 catccatttt tcctaagtaa tctggtgcaa acacttcaat ttgtcgaatg attttcatac
    25621 atttttcctc tttctttaag tataactgat gataggatct taaaaaataa tccaaacgat
    25681 aggatcttta ctcctttgat tttaccgtaa aatgacggtt cttggagtcc ttatctactg
    25741 tttggattac ttttttattt acaggtctcc agtactactg cagacctatt gcaatggcaa
    25801 tcatgatgaa aatagttcct aaaacaaaca ggaatccttg catcttgatt tggaatcttg
    25861 cccattttgc ccattcgatc cgtgcaacac ctagcacacc aatcaagctg gctgatacgg
    25921 gtgtaaaagc gtccataaaa cctgaaccaa gctgataagc aagaactgct acttgtctgg
    25981 atacacctac taaatctgcc agtggagcca tgattggcat agtcaaagct gcttgtcctg
    26041 aatttgatgt aacaaccaag ttgaacaaac tttggaagat gtacatcgcc caagcaccaa
    26101 tgacagctgg aacaccggtc aacgccgtcc cgatcccatg caaaatcgta ttcaaagctg
    26161 aaggaacaga tgcatcagat cctcccaaga caagaagaat ccctttggcc atacctacta
    26221 cgattgctgt accagctaaa tcagctgcac cagattggaa agaagaagcg atgtcattga
    26281 ctttcattcc atctaatttg aaaagaacag caatgattcc agcaactaat cccatcacaa
    26341 agaattgaga agcgatttct ggaatgtaat agcctttttg agtcacgccc caaacgatcc
    26401 agacaaggac aactaacatc tctaataaga tcaatttatg cccaagcatg aattttttat
    26461 tttcatcaga tgtctttttg atatgagaac ggaaataatc atctgatttg taagtcaacg
    26521 aactttctgg ttttttacgg attttttctg catatatcat catataacca gcggctaatg
    26581 cagtaacaac tacccacata atcaatcgga atgtcgcacc agacaacacg gggattccag
    26641 caatcccttg agccaccgct acgctaaacg ggctcatcca agaggtcgca tttccgactt
    26701 gagatgcgac ataagtcacg gttactgcta cgatcgagtc atatcctaac gcaatgacaa
    26761 atggaaccat caccattgag aatggaatta cctcttctgc catcccgaat gtagcgccac
    26821 cgaatgaaaa agcaaagaat aatagcggta aagctaaacg ctccagtccc ttagttttac
    26881 tgataaacgc atagatacct gcgtcgatcg ctccggtacg cataataata ccaaaagcac
    26941 ctccaacaac aaggatcaat gcagcgatcc ctacagcaga tccatactta tctccagata
    27001 ctagtccttc aaaaacaaaa tttaagaaac caaagccgcc aaaatcatct gttccccata
    27061 ttttggctgt tttatgcaat tttttagaag tatcatagat attttcgccg tactgatcgt
    27121 aaagcacatc atctgtcaag gagatttcat ctagtttttc ctgcgtaaga tttttttctc
    27181 cgtcagcaat gactttttcc aatccttttt ccggaacatc cagtttttca cgttctgctg
    27241 gatgatcttg cagttcttct aattgatcaa acacatacga cttatccagc tcgtaagcat
    27301 aacggaagga atcttgacgt aaaacagtac gagtacttgt ttcgccattt gcatctttgt
    27361 attcaatatc ttgcgtgctg aactttcctg ctggaacgac aaaagtcagt atccatgcaa
    27421 agatgactac accaaaaata atgacatacg tatggggtgt cgataattta gtgaagtcgc
    27481 gtttcggttt tcctgaagaa tttgttttct tcaaatttat ttcttccttt cttttttcag
    27541 taattttgat gaataaaaaa tggataatca aatgaattat acagtaa
//
LOCUS       DAFLWQ010000033        27484 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.034, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000033 DAFLWQ010000000
VERSION     DAFLWQ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27484
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.034"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(19..963)
                     /locus_tag="L1V16_001430"
     CDS             complement(19..963)
                     /locus_tag="L1V16_001430"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBN1275776.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1259..2203)
                     /locus_tag="L1V16_001431"
     CDS             complement(1259..2203)
                     /locus_tag="L1V16_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1275777.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2424..3638
                     /locus_tag="L1V16_001432"
     CDS             2424..3638
                     /locus_tag="L1V16_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1275778.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            3660..5675
                     /locus_tag="L1V16_001433"
     CDS             3660..5675
                     /locus_tag="L1V16_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HBN1275779.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(5758..7131)
                     /locus_tag="L1V16_001434"
     CDS             complement(5758..7131)
                     /locus_tag="L1V16_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBN1275780.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7157..7441)
                     /locus_tag="L1V16_001435"
     CDS             complement(7157..7441)
                     /locus_tag="L1V16_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1275781.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7443..9458)
                     /locus_tag="L1V16_001436"
     CDS             complement(7443..9458)
                     /locus_tag="L1V16_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBN1275782.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(9637..9942)
                     /locus_tag="L1V16_001437"
     CDS             complement(9637..9942)
                     /locus_tag="L1V16_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HBN1275783.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10031..11062)
                     /locus_tag="L1V16_001438"
     CDS             complement(10031..11062)
                     /locus_tag="L1V16_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1275784.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11269..12144
                     /locus_tag="L1V16_001439"
     CDS             11269..12144
                     /locus_tag="L1V16_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1275785.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12296..13138)
                     /locus_tag="L1V16_001440"
     CDS             complement(12296..13138)
                     /locus_tag="L1V16_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1275786.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13230..15107)
                     /locus_tag="L1V16_001441"
     CDS             complement(13230..15107)
                     /locus_tag="L1V16_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBN1275787.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15104..16525)
                     /locus_tag="L1V16_001442"
     CDS             complement(15104..16525)
                     /locus_tag="L1V16_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBN1275788.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16528..19917)
                     /locus_tag="L1V16_001443"
     CDS             complement(16528..19917)
                     /locus_tag="L1V16_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBN1275789.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20174..21565
                     /locus_tag="L1V16_001444"
     CDS             20174..21565
                     /locus_tag="L1V16_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1275790.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(21638..22285)
                     /locus_tag="L1V16_001445"
     CDS             complement(21638..22285)
                     /locus_tag="L1V16_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBN1275791.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22293..22979)
                     /locus_tag="L1V16_001446"
     CDS             complement(22293..22979)
                     /locus_tag="L1V16_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1275792.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(22985..24058)
                     /locus_tag="L1V16_001447"
     CDS             complement(22985..24058)
                     /locus_tag="L1V16_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1275793.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24280..24954
                     /locus_tag="L1V16_001448"
     CDS             24280..24954
                     /locus_tag="L1V16_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1275794.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            24959..26299
                     /locus_tag="L1V16_001449"
     CDS             24959..26299
                     /locus_tag="L1V16_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1275795.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26448..27434)
                     /locus_tag="L1V16_001450"
     CDS             complement(26448..27434)
                     /locus_tag="L1V16_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HBN1275796.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         7999 a         5209 c         5000 g         9276 t
ORIGIN      
        1 gttcatattc attgtttctt ataatacagt gttcaatact tctcttaaag cacttgttga
       61 tttgctgaac attgcttttt cttcttcgtt gattgataat tcaacaactt cacgaacacc
      121 attttcgtca acgattgatg gcacacctgt aaagatatct ttttcgtcgt attcaccagt
      181 taaataagca gatacaggca atacagcttg ttcgttattc aagatagctt ttacgatacg
      241 tgcagtactc ataccaatac catagtaagt tgctttttta cgatcaatga tctcataagc
      301 agcattacgg actttatcag caatcacatc taattcatct tgggcaatac gatggtcttt
      361 ttctacaatt tcaaacactg gtttaccacc gacagttgta tgtgaccatg cagcaacttc
      421 tgaatcacca tgttcaccta agatatagcc gtggacgctg cgtgggtcaa cttttaattt
      481 caatgcgatt tctttacgga aacgagttgt atccaatgtt gttccagtac cgataacacg
      541 tgatgttggc agaccagatt cgttccaagc gatatatgtc aaaatatcta ctgggtttga
      601 agcaacaacg ataataccgt cgaatcctga tcccatgatt tcttttacga tttggcgcat
      661 gattgacgca tttgttttaa ctaaatctaa acgagattga ccaggttttt ggttgatacc
      721 agctgtgata acaacgatat cagcatcttt acattcttca tagccacctg accatacagc
      781 cacattttca tcgccccaag ccataccatc taaaaggtcc aatgcttccc cttctgcttt
      841 ttcttgattc acatcgatca atactaattc attagagatt ccttggttga tcattgcata
      901 agcgatactt gttccaacaa aacctgtacc gacgattact actttacgac ttgttttttt
      961 catgaataaa cagctccttt tcataactat ttgttacttt catgaaaagt atagtcttgt
     1021 ttattcattt tatcaacatg ttaattataa tagttgttat tataattttt gatggaaacg
     1081 aattcctgaa tacgcataac agataaatga caaatgttta cacctatatc ccctgataat
     1141 acaaccaaaa gtttagaact gaaaataaat ccaaaaaaat tcgctgcaac gatataataa
     1201 gacagcaatc gcacctaaaa caattttcct tcatatgctt tagtgaaaga ttttcttctt
     1261 aatgtttatt tctccattca ttgggagtac atgttgaata cttcttgaat aatttgaata
     1321 aagaagtcgt ttgtttatat ccgatacgat tagcgatttc ttccaacgaa aaactcgttt
     1381 cttgaatcag ttccaacgca aagtcgaatt ttttctttag aaccagttct tgaaaggaag
     1441 catcaaaata cattttcaat ttattactaa gatagaccgg attgtagcca aaatgagctg
     1501 ctgtttcttt taacgtacaa gaagtaaaat gcttatcgat ataatctaat actctaagca
     1561 tctcattttc tgcgcatcca tctgctgatg aaaagctttg ttgttctaat aaatgagtca
     1621 attcgatcag taatagtgat gtatagagat ttaacgaacg gatcttatga ctgtatgtat
     1681 caaaataaat caacagcata ttttcaatca aatgcgtcaa acgacttgtt tttccgccgc
     1741 gaaaatgaat gaattgtgta tgttcccctt tttcttttga tgcatttatc aaaaaagaag
     1801 aaagtagatt atttgtgctt gccaaatgat tcaatatctc tgtagataag gtttcttctt
     1861 ttaataagat gttgattaaa atatcctctt gccctgtgta ttcgattctt tgagtagctt
     1921 ctttatcaat gatcaccacg tcactttctt ccatctctat cctttctcca ttaataattt
     1981 gtaaacatgt accgctatac atataattga tttcaacaaa atcatgtgta tgctcgggaa
     2041 cttccgcata tcgacggtgt ttactgatat gaatatttcc ctgttgaaat agatcccctc
     2101 ggtggatttt tggcggtgtc tgaagatggt aagctaagtt taaatcattg atattcattc
     2161 cttgttcacg ctgcagagtt tcgattgatt cttcgttacg caaaaaaaat gtctaattca
     2221 gctagttcca attgactccc tcctttttgt aagcggtttc tttcgcttat tagttcacgc
     2281 tgtactgcta ttatatgcaa agctattttt ggtttcataa agactttcta tggttgggac
     2341 atgaacttcc tgtgattccg ctattgagag aataaccact tcatactata tttttgataa
     2401 gcgcttacaa aaatgaaagg aacatgctta tgaataaaaa gatgatgaaa ttttctctgc
     2461 tgtcagtctc tcttattttg acttctgctg gtgcagtcac gtctgcaatt cccagtatgt
     2521 cagctactta tgccacgcgt tctttatctg ctgttgaatt attaacgact gctccctctt
     2581 ttatggtcac tatttttgtt ttgattagta gttttattgc taggaaaatc ggacaaaaac
     2641 aaactgtgat catcggatta gtgattgcat cgatttgtgg tatcctcccc ctcttctcac
     2701 aaagttacag tattgtctta gcttcaagag ctggactagg tattggcttt ggattgatca
     2761 attctttggc agtcagcatg attgctgcct tttatcacgg agatgaacga gcctctatga
     2821 ttggttttca aagtgcattt caaggatttg gtgcagcttt aatgacattt gttgcaggac
     2881 agctagtaca gttcggttgg caatatacct ttttagtcta cgccatcagc ttacctattc
     2941 ttgtcttgtt tgttttgttt gttcctacac ctgaaacaac tgaacttcaa tcgcatggca
     3001 cagccccaac aagacaagta atcaaaacga atcctaaaat gattagttat ggtatttttc
     3061 tcttgctggt catcgtggta tataatgctg tatcgattaa attagccaca gtcctgacga
     3121 cttattctct aggaaacgaa actaatgcag cgaatatctt aacaatcatg caattggcaa
     3181 gtatggctgc cggagtttgt tttggctggc ttcagacaaa agcacatcgc tatatgctta
     3241 cactttcttt actactgatg ggaatcggct ttgtattgat tgccactgtg ataaacctgt
     3301 atgtgattgg gtttggtgcg atcctaacag gaatttcttt ttcgttattc attccttact
     3361 tattcaacca agtaagtatc caagcgccca agtacgcgga gagtttcaat acttcaatct
     3421 tattggttgg cgctaattta ggtactttca ttgcaccata tggtttgctc tttctctctt
     3481 ttgcttctct tgggagtaaa acacttgctg ttttcgtcaa tggcagtatc ttgctgttga
     3541 ttagcgcgct tattagcctt ctagtagtac acaggacgaa tagaaagaca gtgataagag
     3601 tagatgaaga aataaaagaa caattgacaa caaaataaat ttgatggagg tcgtgtaaaa
     3661 tgacaaatga aaaacataaa gatagatggc tttggtatcc tggagacttt gagatccgcc
     3721 atggactgct acaaaatttc caacgggaag aacgaggttt tgactggcca gcgtactggt
     3781 acatggatga ttgccatcgg aacgtcaagt ttaagagata ttactttctt gatcaacctt
     3841 ccatgtttaa agtgacgatc caaggagttg ggtatgtaga aattaatgga caaaaacatc
     3901 catgtggaaa atggctgact tgtccagctg gtaaagcaaa aattcgtatc tttgtaggac
     3961 atacatcagg gctaccagcg atgtttatcg agggagacga agtaaaatca gatattggct
     4021 ggacagcaag taattttatt gaagaatatc cagctggctg gagtccgctt tatgtcgata
     4081 tcgcaaaaga tccaaatcaa atctattatc aaaaagaatg cgtccatcca gtcactgaaa
     4141 cggagattgg cggaggaatc ttattcgatt ttgggcgagc agtgaatggc tgtgtagaac
     4201 taatatctct ggatgaccat atcgaatcta tcactctatg ttatggagag tccgatgtag
     4261 aagctatgga tatcgattat tgctactata agcaaatagg aatgacaaga aaaatgaaag
     4321 ctcgtaaacg cgcttttcgc tatttgttta taccagaggt ttctactgga atggttcaac
     4381 ttcaagtttt tcatgaattt ttatctcttt cgaaacaagc tgctttttca agcgattctt
     4441 ctttactgaa tcagatctgg tcagtatcag aagaagcctt caagttatgt agtgatttgt
     4501 tttttatcga cggtatcaaa cgagatcgct ggatttggtc tggagatgcg tatcaatcat
     4561 tcatgatcaa tcaatatctt ttttttgacg aggaaatcaa taaacgaacg atattagcat
     4621 taagaggaca aaatgaaatc aagcagcata tgaatactat cgttgactat tcgatcttgt
     4681 ggttgattgg tatcgaaaac cactatatga tgacgaaaga ctatgaattt ttacgcatcg
     4741 tctaccctaa gatgcaatca ttaatgagat acttgatgga gcaaacgaat gaattagggt
     4801 ttatttatgg gagagcaaaa gattggatat ttattgattg gtctgaaatg gataaagaag
     4861 gaacgcttgc tgcagaacaa gtcttattac tgaaagccta tcattccatg atcacttgcg
     4921 gagatatctt agctgaaaca tatggagaga acgaaaatta tcatactcat ctctatcaag
     4981 aaaaatatca actattgaaa caaaacctat ttgactactt ttgggatgaa gaacttggcg
     5041 cttttatcga ttgctatgaa tctgggagaa gaaatgtgac gcgtcatgcg aatattttcg
     5101 ctgttttatt cgattttgct aacaaagacc aacagcaatc gatcttaaag aatgtcttat
     5161 tgaatgacac tatcacacag attactactc catatttcaa attctatgaa caagatgctt
     5221 tatgcaaact cggacagacg aatatcgtct accaaacgat tcttgattat tggggaggga
     5281 tgttatctca tgatgcggta actttctggg aagaatacga ccctactcaa acaggaaatg
     5341 aaaagtacag tatgtatgga gatccttatg gaaaaagctt atgccatgca tggggagcaa
     5401 gcccaatcta tcttttagga cgctatttta tcggtttgta tccaacaaag ccaggttatg
     5461 aagaatttat gatacaacct aatctagatt catttgaaac actgaattgt acgctaccta
     5521 tcaaagatgg aaagatttcg cttgaaaaaa caaaagataa gatcgtgatt acttctgata
     5581 gaacaggcgg aacagtgaaa atgaatggta aaagttatcc tcttctagca aaacagccac
     5641 ttgtcttaac aagctattca aaaataaatg cataaaacaa aaaactgctt gcgacatatc
     5701 agaagacttt aaatcttctt ctgatattgt ccaagcaatt tttattttga agtttgctta
     5761 attctgttct ttagaaacaa tgtttgttct ttttccggca aaaagaaagc tagataatac
     5821 gacaagtaaa aagaaagcga tgattccaac tgtcaaggct atttgaccgt attctcctag
     5881 tttcccaagt acaagtcctg gtactagata atcagtatcg gcaaatgtag aagaagcgat
     5941 tttaagatct cctaatactg gaaggataaa taatggcagc caactaatca ataagctatt
     6001 gaaagcagaa cctaataccg cccctcttct accgccagtc gagttgccga agacaccaga
     6061 agcagctccg cagaagaaat gtcctactac cccaggaatg ataactgtag tttgcaagcc
     6121 tatcatagca aacatggata gtgttcctac aaagaagcta acaaaaaagc caattaatac
     6181 agcattaggt gcatatggaa aaacgatagg aacatctaat gctggtttag aatcgggtac
     6241 gagtttttta gcaatccctt ggaatgctgg aacgatttct gccaacacca ttcgaacccc
     6301 ttgaaggacg ataacaaacc cagctgtgaa tgttccagct tggatcagtg caaagattac
     6361 agcgttgtct ccattgctta gttctctttc aacaaatcca ggaccagcta acaaagcaag
     6421 tgcgacatat acgatcgaca tcaagagcat gatcgataca gtagaatctc gcaaaaagct
     6481 gaaactttta ggaatcttta tgtcctctgt agaacggtct ttgtttccaa aaaactttcc
     6541 gatccatcca ctagaagcat aaccgatatt tccggtatgc cctaacgcaa cttgattgtt
     6601 tccagtgatg ttcttcataa acggttgaca aagagcaggc gtaatagtta atagtgttcc
     6661 ttcgaagacc ccgcctaata agatcatcca caaatttgca gtaaaccccg cgcttactaa
     6721 aatgactgct gttagacaag aaacataaag cattgcttga cctgtaagaa aaatgaattt
     6781 atatcttgtg aatctagcaa gtaaaatatt cacgatcatc cctactagca tgatcaaagc
     6841 agtaggtgta ccgtattgtt gcaaagcaat cgccactact gcttcattgc taggaactac
     6901 tccttgagta tgcagagctg tttggaacat cgaagcaaaa ggggttagtg aattactgat
     6961 taaaccagca ccgccgatca gtactaggaa tccgacaaat gttttgatag ttccttggat
     7021 cacttctgaa aatttcttct tctgaagaac gagaccaagc agtgcaatca aagaaacgag
     7081 gatggagggc tgactgacga ttgacacaaa caaattcaac aatttatcca ttgatagttc
     7141 ctcccttgaa tcatttttat tcttttgaca agatcttcgt tactttttct tttacttctt
     7201 cgctgtcaat gatcgattgc aaaggtacga gcttttcatc aggtatagaa gttagcgtat
     7261 ctttcaaaga atgctcaatg aagaaataat cagccatatc gctagataca cttccaacat
     7321 ccgtatgact tacttcaaac tcgtccacat ctgctccaag atctgcaagt gcttgtttga
     7381 tgttcatctc taccataaaa cttgttccta atccactttg acatactgca aaaattttca
     7441 tatcattcgt ctccttttct tatgatcgct aatatttctt cttttgttga tgcgtgtaat
     7501 aaatcttgaa gattttgttt attagaaagt agctttgtta aatttgccaa agcccgaaga
     7561 tgtgcctcat tatcgatagc agctaaacag atgaacaaac taatgggatg ggctggatta
     7621 tcaagcagat ccacaggttg ttgaagtttc agcaaagaca tccctacttc gtttacgcca
     7681 tcttctggac gagcatgagg taatgcgatg tgatcgccaa tatggataaa cgcaccatac
     7741 tgctccacgc gctcgatcat agctttgata taactttctt ctattttatt ttctgataat
     7801 agcggctgtg cggcaaatgt gattgcttct tgccagtttt ttggttgatc cgataattgg
     7861 atcatttctt ctgttaataa ttcagatagc ataggacgtt gatcctcctt cttttctaaa
     7921 agtttgttca ttttacgatt taatacttga tagagctttt cttcgtctac gccttctttt
     7981 aattcgatat aaggcagtag cgccgacaac aattcttggg cagaaggcat tgaaaatcct
     8041 ggtatcagcc aatctctttg tacttgattg atcagctgat ttttttccaa gtcagtcatg
     8101 attggatgca gaacatagag agactttttc ttatcagtaa gtgtgagagg tacagtagaa
     8161 aaaataatat cgtaagaagt ttcgtcaacc tcgtgtaagc ggtcagctga attagtctct
     8221 gtaaaaaaga tcatcgggaa taattgctga agttcacttt ttaagatcaa tgaagagcta
     8281 atgccacttg gacagacgat cacggctctt atttttctat ttctttcttc tgcgtccgct
     8341 tttctgatct ctccgccaaa tagtatagtg aaaaaaccaa tctcttcttc agggatgctc
     8401 ttccctattc gtctttctaa cggaagtaat gcttttcttg tcatttcgta gatggaagca
     8461 tattgatgct taatttgatc gatcatcaca ttaggtaaat aaaaagaata ggaaatacga
     8521 aaataggcag ggaccaagtg ataaaagaca ttcatcaata attcacgaaa cgaagcaaat
     8581 tctacggcca tcaggaattc catgcgatgg atgacttctg aagaacattc cagcaaaaaa
     8641 tcaagtgcag gctcctggac atctccttca acgatcgatg ctaagcaaag agagaaaaat
     8701 ataatctccg aattttgatg ttcggaatag ccaaggccag tcaatacttg tcgactaatg
     8761 tcagtgactg caagagaagc caacagttca gcatctttta ccagttccat ggatgttttt
     8821 ccaattcgaa tggttgtcaa actcaaataa taagctaatt catccattcg atttggtgcg
     8881 aatcgaagat ctgatagtga aatcgtttta tctagcaaat ctctaacttt ggcgtaataa
     8941 tcaatggaaa gggttgcggt taaatacgtg agcccaaatc ttccagcaag tgactgcatc
     9001 aaacgagcag tgcgattttt tgcttctctt cttaatattg cttctgaccc tagcagccta
     9061 aaaccagttt tcctagtata cgacagctga caatcttcca cttctaattc atttcttatc
     9121 tttttgatat ctgacaggac tgtcccttta gaaacctgaa gaaaatcttg aaaatgaaaa
     9181 acagaaacag acgttgcagt cgaataaacc atcaaataaa gaagatctct tcgctcttgt
     9241 tcggtataca cagcttcaaa tcgagtaata tccaaaaatt tttctgccca gtcgattgct
     9301 cggaatttct ttatacggat acgggtatca tccacatatt cggcaaaagg agttaattgt
     9361 ttgatcgcct cgcttgtatt tacttcgatg atctctgctg ctttttctag actgatttct
     9421 cttggtgttt tcaggagata actaattttg tagttcacag cgctgttcac ctcctactta
     9481 tattctagta tggtagcgct tttaaatcga ggggtgtttg gtacaactta cagttggatt
     9541 ttttttacga ctgtaccgaa cgatttctat cgaatggata cagaaaaaaa gcaggtgacc
     9601 aaatgtctcc tgcttttatg aattgatttc gtccgatcaa tgatgatcat gtttattttt
     9661 tgaggtcagt tcttcaaatt tttctttgac atcttcaacc gctttttcga tatctttttc
     9721 aaagtgattg ggctcattag gctttgtttc ctcttctaca gaatttgaac cagataaagc
     9781 tgtttcttta ttttctgttt caccagagtt tgtgccagct aatgattctt ctttgtcttc
     9841 tgtttcacca gaattagttc ctgctaaagc cacttcttct tctgttttag gggccattga
     9901 acctcttaat cgtttgtgtt tttcaccgtc ataatttgtc atgttggttc ctcctagtag
     9961 ttctatactt tttcatcgta caataagaca gtttatgcgt caaaaaacaa acccgattct
    10021 tacaaatatg tcatattttt ccttctgatt cttgaatgct tttgattcct tcttccaaaa
    10081 ttttcatttg taagattgtt tcttcatctt tgatgacttt ttctgcgcca ttaactaatg
    10141 tctcgtaaat cccttcgtag acacggctgt aatcaccaac ctcggaaatt actttttctt
    10201 catgataact cccttgttca tctatatagg tcaatacacc ataatgttcg ggcaaatcga
    10261 taccaaagtc ttcatgatca ggcatgtaaa acattttcag atgttcttct tgtcgatctt
    10321 ttgtttgttt cacgaacatc cctttttttc cgtaaacgac gaaacttgga cgttctttga
    10381 tgcggaaata actggatttt atcgaaattt tcatatttcc atagaaaaaa tccagatcga
    10441 agtaatcatt cattcgtcct ttccctaaaa gttgacgtac atcatagctg atatcatctg
    10501 gttcgccgaa ataagaaaga acttgatcta ctgtatgaca agcatgtcca tataaatagc
    10561 tgttcgcagt agaaaattca tgcgtatttt ctggtacttc cggtctgaaa taatcataat
    10621 gcatttctac ttctaaaata tcccctaatt ttccgctttc gattactttt tggactgtca
    10681 agaagtcaga atcgaaccgt ctgttttggt aacattggat aaatagacct ttttcttttg
    10741 ctaatgcaaa taactcttct gcttcctttg acgtttctgc aaaaggtttc tctactagta
    10801 cattcttacc atgttcgagt gccatttttc catattcata atgaaattga ctaggtgtag
    10861 tgatgacaac taattggatc tcaggatcat cccaaagatc agacagctga tcagtatatt
    10921 cgatgtcttc gaatgttttc cacactggtt cagatgggga aaaaattttt ttgatattga
    10981 ttttgttcgt aagttttctt gaaaaaggca aatgatagcg atttgtactc tttccattgc
    11041 caagataagc gattgtaagc atgagtggtg cctcctttta ttgatgtttt cagtatatcc
    11101 tagaaaagcg cagaaagtat ttataatagc tattctggta aaaaagttca gaaaaacact
    11161 tgttatcatt cggtttggtg aaattaatgt tcaaagtaag gataaaaatc aaaaagatag
    11221 tagcggaacc aagtgtttat cagtaagata gaatttggag gtcagatcat gcttattgaa
    11281 gaaaaactaa caaaacaaga gttgtttacc acgacagaga aacggattgt cgattacatc
    11341 cgtaggaata tcgaagctgc agtctacatg acgattgaag aattagcaaa agctacgtat
    11401 acttcccatt cagctatcat tcgtttatgc aaaaaaatgg gattcagcgg atttaaagaa
    11461 ttccgtttcg agctggggcg ggaagttcat caattgattg ctcagttcaa tcaaacgatt
    11521 gatcctaatt ttcctttttc aagtgaagat agcactcagc aaattgcaaa gaaaatggcg
    11581 gatttatcga tccagtcaat aaaaaaagca caattgcaga ttgaacatga agatttagat
    11641 caaatcggta aagtattgaa caaggcacag cgaatctttc tttttgcaaa aggtgattct
    11701 caaatcacgg caaggaaatt ccagaataaa atggtcaagt tgaataagtt tttgatcatg
    11761 gctgaagaat acagtgattc ttcttggaat gcagccaatt tgactagcga ggattgcgcc
    11821 atttttatta gctacagcgg tcgcatccat cattatgaac gaataatgac ctatttgaag
    11881 catgtagagg cccctacctt gctgattacc ggaaatcagc attcagaaat ggccaaacag
    11941 gctgatatgt gtcttgttat atcgcaggag gaatatgatt ttgctaaagt agcgactttc
    12001 tcctctcaaa ttgccttcga ttacgtatta aatacgttat tctcagtgat atattctcaa
    12061 aattttgaag agaatatccg caacttgaaa aacaaacaag aattgatgca aaaaggcctt
    12121 cttaaagaat atcggaaaac ttaagaaaag atcctcattt agtaataaga aagatagtgt
    12181 ttgataggct ctctttgata tcatcataaa aacaggctga agttttcttt ttcaaacctc
    12241 agcctgtttg tttacggaac gattcgaata gatatattat agaaatgagg aatagctaac
    12301 ttctgtttct tattttgaac gattgacgaa aaagatatat aagaaggagg aaaatcagta
    12361 tacatgcagc taacaatcca tacaggaaaa atcgtttgtt ctcggatact ttctgtactt
    12421 ctttttgaac ttcttttgca tgataaggaa cccggtgccc tctgacaagt aagcgatgac
    12481 tgttgaccat ataaggtgta caagttagga gtgtcacgaa atcctgccct ttttcgattc
    12541 tcagatcttt tgtatcagtc ggttctaccg tcttgatctg atcgacttga taagcgagtg
    12601 tccgtccatt gatttcgata tagaaagaat cacctaaagt cagtttcggt aagtctgtga
    12661 acaactttgc ttgaggcagt cctcgatggc tggaaataac ggcatgtgta ttttctcccc
    12721 ccgtaggata agacgttcct tccaataatg aggcaccttt ttctagcagc acagtattcg
    12781 tttcatcaaa aattggcaaa tggacattga tctcagggat cgtcaaaata ccgatcgtat
    12841 gtttctcaaa ataggttcta tcctttttcg caggttcttt tttcttagta aagggatctg
    12901 cacctggatt tccaccttct tttgctaatt gctggttttt ctttgtcatg ttttcttgga
    12961 ttttagccat gacttcttca ttttctttga ccgcttgttg ctgataatga gagatgatct
    13021 gctgatccag ataattattc agcgcgtcgc taacaaatgg ataagctagt atccctattc
    13081 ctgagagaag caagaaaagc atcagcagat ctagaagttt ccttttcttt ggtttcattt
    13141 gtgttctcct tgtgatgact gtttgataat aaaagaaaaa ggagcatttg cgtaatccgc
    13201 tgctcctttt tccaattctt gcaaaaagac taaatctgac tgtgcttgcg tctagcaaag
    13261 tacagtccag caatcagtag aaggactact cctgcaccga tatacacata gattccctta
    13321 ccgcctgttg aaggaagtgt acctttgtgt ttatttggta ttttttcagg agaaatcaac
    13381 tgtcctgctg ttacataaga ttgttcatcg atagtaaatg ctacacggtt tgttaatgga
    13441 acatattttt ctggcgcttt cgtttcttcc agatagtacg tgccatattt tagacctgtc
    13501 acatcgatta aaccgttact tgtggttgta aaaaccgttg ctgattcttt cgccgatacc
    13561 cagctgacgg cttttgtgga tgggtcgatc gataaatatt tcgctgtgtc actatcttga
    13621 tcacgaacga cgaattctgc tccagcaagt gtttggtctg atgtaacgtc accatctact
    13681 ttaacaaatc gtttgccccc agtaacgaca tcgactgacg gtggtgtttg atcatttgta
    13741 tgcccgttat cgacatttgc ttggttagaa aatcctttgg ttggatctgc tttttcgttc
    13801 aaatgcatat agtaaacgaa tttcaatgta ccgccaggag ttaatgaagg aatataattc
    13861 ggatcaactg aaaccgtgaa tccgtctgtt tgctcagtga cagaataatt tactgggtcg
    13921 atttctttat ttccatcata taaggcataa gcatacgttc ctgaagaatc attatcaaat
    13981 gttaaagcag cgtcatgagt atcgataagt ttgaatgttg tgtacttgtt ttgcgttcct
    14041 tctttatcag cgatacctaa tgggatattg acagaaatct catattgaat tttttcaccg
    14101 attgcgacat cttttccatt caattgaggt gttgttttat caactttaga cgtatcattt
    14161 ttgatggtct tttctactgg tgtttggcta tttgccagga tctcaaaagg cgtgattgtt
    14221 tgcttttcaa tcatttccgc attatcagga gcttttactt cttctaaatt atattttcca
    14281 acttctaaat gattaacgat caactggcct ttttcaatag atgcctcggc aaagtcattg
    14341 ttgccgatgt cataagaatg accagtaatg aaatgtttgg ctttggtttg atcagttgtc
    14401 caagtgtaca atccatctgt gacactttgg atgtattttt tgacgcttgg tgttccttct
    14461 tctttagaaa taataaattc tgctccattt agtgcttcgt tttcggcagt accgattttt
    14521 gtaactttca acgttccatc attaccgact gtatttttag ggtagagatg gatagtatct
    14581 agttcttctg tcccgtattt ataagagcca tctgcttgtt tgatcatctc atatacaggg
    14641 aaagctaaaa ccatgtttgc ggcagctgac actccgtctt ttggttcttc tttgatcgtg
    14701 tagactgcat ctttcccatt ttgtttttta ggtaaagata aagtgacatt tccatcagca
    14761 tctgtcgttc ctgaagcaac tggtgtacca ggagtcaaag actggactgc ttgttttgct
    14821 gcatccacgg acgctccttt atctcgttgc gcataaaatt cttgagtgac gttataaact
    14881 gaaaatgaaa tatcggctaa tccttggtat tgatcgaatt cgctcatttc tttcccgctg
    14941 ttttggatta aaggatcggg taaatcagtc attttctttt tatgaaggat gacttgagct
    15001 gctgtctcct ctgcaaacac tttttttgcg ccgaagctgt ttgtgagtaa tggtaaaata
    15061 aggaaaagga ctcctaacat aacgtttatt tttttatgat ttttcatttt ttcactcctg
    15121 ttcttttttt gataaacaac cagattgcaa agcttgcgaa taccatacca acaacgccta
    15181 aaagtgtatt tttcgtttcg tttgtttttg gaagaaatgg acggctattt tcttttttat
    15241 tgactacttt caatatactg tccgcctctt tatcctcaga aagaaaagtt gaaatggtaa
    15301 acggaatttc tgtttcactt aaaatataac cagaaggtgc ttcgatctct tttaatcgat
    15361 aacttcctgt tttcaacccg gaaattgaaa aagcgccatt tttatcggaa atcaggtgaa
    15421 gcgcatctga ttcgttcttt gtccacttgt atccgttggc tgtttgctgg aggtaatttc
    15481 ctgctttgtt tttaataagg aatactgcgc cagctaatcg tttatctggt ttatttgtct
    15541 cgattttgac aaattgctta ctccctgtat atacagagac tttctttgta ctgacaccaa
    15601 aaccaaaatc cagtgttccg ttgttgttga tttccttgtt cgcctgtgct gtactgctta
    15661 gctgcatctg ataagaaatg gtcagttttt ttccagcata tttttccaac gaagggatcg
    15721 aaaataaaac atcaaatccg tgaggtttct tgtgtatgac aaagccttct gtcagctttt
    15781 ctccattcga tgaaatcgtt aaactattag gtaaaaacgt taatgcttca tccgcactat
    15841 ctgacaattc gaacttttga tagtcaagga tatttacagg aattgtcgta tgcaaggaat
    15901 aagtgatttt ttcaccaatc gtaaaatcat ttctaggctc ttctaatacc ttctcaaaag
    15961 gtggatcagg gtagtcgttt tcttcatttt taggatacaa atggatagtt gaaagttttt
    16021 gattgttttg tccatgtaca ggaagaacaa ctaccatatt ctctgccttt tctttgacga
    16081 cttctggtac tttggattca atgaaaagat acgctttatc tcttttttct tgatctttag
    16141 cggccagaga aaaagaagcg ataccatctt cgttgttaag agttgtagtt gttgcttctg
    16201 cggtaaacat accggaagac gcaccgtttt ttgcgatctc tgcttgtgct tcttctaccg
    16261 ttttgccctt ttcccgtaga tggtaaaaag aatctgtgac atcataaact tggaatgtga
    16321 caccatttaa tcctcgatac gtttgtaata aagctttttc ttgtccgtca tttggatgat
    16381 ttttcggcag ttgcccgttt gggaaaagca atttgtgtaa agtaatctga accatttctg
    16441 tttctgtttc tgttgctacc tgagtaaaag ctggtttaaa tagtaacaag aagagacaca
    16501 tactaagcca accaagtttt ttcatattta gctgccccct ctttcttttt tcaaaaaaag
    16561 ataccaaata gaaaacgcac aaccaatcat ccctactaga tagattccta aacggccaat
    16621 tcctcccgtt tcaggtaatg gtacttttgc ctgattcgtg atgtctaaag aaatctggtt
    16681 gtttttggct cctggtgaca gaacagattc atgatcttgt ccatccactt gaattgaccc
    16741 atcttcgtgt ataactatag taactggctc ttttagacct tggtatcctt ctggtgtaaa
    16801 agtttcggtc agcgtataag ttccaggttt taaattttcg aatagaaagg tatctgtttc
    16861 ttgtccatct tttggcgatt ctaagtccat ttctggtccc tgcagtctga attttgctcc
    16921 ttttaatgtc tgtccgttgt cttctttttt gtgtaccgtt agatcaaacg cttttagtcg
    16981 attttgatga gtgagcgtcc atacattatt tgtcatctcg gtattttttc ccgtgtaaat
    17041 gatttttcca tatttatcga tttggaattc ataatttccc ggcgaagtat catatccggc
    17101 aggaccagct gtttcaacga ctcgatattt accaggtgtg agtgaatcaa aactggcaag
    17161 acctttttca ttcgttgttt ggctgtcaat tggctgataa gtaccatttg cttctttttt
    17221 ctgtagggaa aatgctgctc ctttaagatt tatctctttg tccgtccctt gcatcgcata
    17281 cttacgtact gctacaggaa cttcaacaaa aggattttca atagtcaact ggatcgtatc
    17341 atcggaagta gtgactgttt ttccatcaat ggttaccgta ccatcagaag cgatcttgat
    17401 ttcccaagta gtctttttgc ttaatccatg cccttctgga gcttttgttt ctgtcagcgt
    17461 ataggtcatt tctttttgca atttgacatt ttctggaaga gaataggttc cgtcgccatg
    17521 atctgttagt aaagtatcaa tagaatctcc tgttaatttg aaaacagcgc caataagatc
    17581 cttttcacct gtagaggaat ttttcgttat tttcaagttt aacggtgtga attgtttagt
    17641 atttttccat gtcattgcat ctatttgttg agaatcgtat cctggtacag gtaattcttt
    17701 gattgtttgg taactgaatg cttgaccttg attattgtat tgaggtagtg ataatatctc
    17761 ttgataactt tctccgctat ttgcagataa tttgtcaatg tctgcacgtt cccacgtatt
    17821 tgttgtatct ttagctggtt taatgattcg aatatatccg tttttccaag ctgcagcatt
    17881 tgtcgtatgt tcccgttgaa tctcaaaagt aacttgatct ggacgatcag ctagattgtt
    17941 gtcaaattct tcccataact ttttgatgtg aagactgact ccgggagctt tagcagatgg
    18001 tataccgaat tcagctaatt cattggtatc aatgtttggc tggaaagttg tcctgccgtt
    18061 catttgatac cagaaatttg gatggaagtc ctcattttct gtttggattc tcacttggta
    18121 atggatttgg atttcttggt cttttcctaa atagatctga ttgctcttga tggtatttcc
    18181 ttctatggaa atagatggag tgaccgttgt aggacttgtc cccacactct tgactgaaag
    18241 tgtaccaggc tgataaatga atggttctgc gattggatca tttatttgtc cattgcttac
    18301 agttgctgag atctgtacag cttttttggc taggtattca gagatatctg ttgcatgatc
    18361 agctgattca tagtaaagat cgcctttttc atctgatgaa accatttgtc gcatacgaga
    18421 ctctacttct gcttttgaga gaccagctgc cggatcgctt tgaagttgga tgccaagacc
    18481 atgtatttcg attcctcgtt ctttgagtgc catcgcttct ccgatggttg cgataaacgt
    18541 actgtcgatt cttctggata gattgttttg gtcaggtgca tcatagattc ttgagattag
    18601 agaagtattt cccggccgat cttgcgtatt agaaaactga gttccgtaat aattgctgct
    18661 tgattgtgcg tgtacccgct gtactttata ggaaaatgtt ggtacaccat ccgtcagcaa
    18721 aacgatcact tttttatgtc catttggaac ggatagcatg cttcctgcat ctcttagtgc
    18781 tttttgtgta aaagtaccac catttgtccg tgaaggtgta atggatttta cttgattttt
    18841 cactgaatca aatgaaccca tctgtactgc accgttactg tagctatatc cttcgcttga
    18901 gtagccgaca tatcccatat tgattttgtc tgtgataccg ctatctgcta aagtatcgac
    18961 aaaacgatcg acaccaatct ttacttcacc gatccgatta ttgtcgttca tacttcctga
    19021 ccagtctacg accaatacga gatcaagagg cgtgatatct ttttgtacat ttccacgagc
    19081 attcaaataa acatcaaaca atccgggtgt acttgtttcc tttgcatact ttcgtatcgc
    19141 atagtctgct tgattaccgg ttcctccata ttcgatatac gaatgggtcc gatcattagg
    19201 atctccattc caagaattta taccatccca ttgatttgtt ccgtttttat tgccttgatg
    19261 atcaagaaca tttgtatttc ctgtaggttg ccaactggct ttaggataag tgccctgatc
    19321 atctgttgta tattctgtag gaatcgtttg attagatggc acactcacag ctggcaagga
    19381 taatgtaggc aatgtaaatg ggctgacaga attttcgttt tcttttgatg attcttcttc
    19441 tatttcgtct ggctttggta ctgacacatc tgtatctttc ttattttctg tctcatcaat
    19501 aatgtcatat tctttattat cgacgatcag cttgtttgcc tggctgtggt aaagtgctgg
    19561 atcgattgga aaactcagat cgatagtttg tttagtgttt gatgagattt ccaacgtaat
    19621 tttcccgcta tttacctgat aagcatagcc atctccttct tttctttcca catcacttaa
    19681 gtaattttcg actagaccaa tttctttttc tatcttttca gcactggtgt tattcgcatt
    19741 tagcttgatg ttcagtgctt tttttccaga ctgatccgaa atgacttcag ctgaaattgt
    19801 ttctaaaact gttggatcat ctgtagtgtc tgctattgca gataatggca caaagtttga
    19861 taaactcaat attatcagca tgaaaataac tttcagtttc ttccctgtgg tcgtcatttt
    19921 tcccctcctt tttctttttt tctgttttga cgtgaatagt gaaaattatt aaaataaaca
    19981 ggcgttacat aattttattt attttaatat gataattatt atacgaaggg cgctaaaggg
    20041 aatcacacca attttcatac caattggttt catttatgaa gttgattcct tcgattaatg
    20101 agcgtttcat tgaaagaaaa gggttgaggg agaaaaacat atgatcaggt tgttggaatt
    20161 aaactataga aagatggaaa aaatcattcg aattctgtcc atttctgaca agtggatgac
    20221 taaaaaagaa cttgccaaac gaattggtag ttcagaatct acatttgtaa ggtatatcga
    20281 agagatcaaa atccgctggg gaacggatgt aacgattcaa tcttcacaaa aattggggta
    20341 tcgtcttgaa catttgaatg taccagctta tttaaatgtt ctgatggaaa tgtcgcaaag
    20401 ttctacaaac agtcgtttat taaatgagat tattgtcaat ccgggtaaaa cgattgagta
    20461 ttattgtgaa aaaatttcca tcagccggtc ttcttttaca cgtaagttga aacaatgcaa
    20521 tcaaatttta gaaagctatt tattaaaagt gatcgttgac caaggttttc agttaactag
    20581 ccttaaaagt gagctccagt tgcgtatctt tgttaccttt ttctttttaa gttactacgg
    20641 aagacgcacg ttgccatttc caatcgaaaa aaagaagatc aaagaaatta tggtcaagaa
    20701 taattgtcag atgaatttgt ttcaggaaga aagcccatat gagcaatctt tctttattat
    20761 gtattttgtt gtgcatctca tgagagaatc ccaaggaact ccatttgaat ggaaagctgg
    20821 agactcttat gtacagttga taaatatcga taaaaaagac ttcttaatct tgaaaaatct
    20881 cttaggaaaa ttgaagtaca gcagctatat aaaagtagtg aactattttg tcaatacgat
    20941 tttttcagaa ttttcggaga aagaaaaaaa tgaaatcagt gagcagatac gaaaaaatat
    21001 gtcctactgt tcgttttcat ccgctgattg caaagaaaaa aacgaagaat atgttgttca
    21061 attattaacg caaatttatt ttttctcccg tattttccca tacgatacga ctcatttgac
    21121 gatccgtgca acttactttg cacagcagat gcaacaccgc cagatacgtc tatatgctgg
    21181 atttcgtgca gaacttcaat tttattccac tctactgaat cagaatctga tttattattt
    21241 atctagctat atcttttgga tgcttatcgg taatcctgaa attcaccatt atacttctga
    21301 taaaaaaata ctgattatca gcgacttaag tcttcgacat agtcaatata ttgaagaata
    21361 tatcagtgat attcttgctg tgcataaaat tcactctgag acaactgcta ttactgaaga
    21421 tcagctgtcg aaatacaatc ttctcgagta tgatctgatc gttacgaatc aacccatttt
    21481 gaatgcccat gttcctcata tattgattga tgatagtgtg tcattcgcaa atgaagaaga
    21541 actcatccgc ttattcgagt tatgaataat caaaaaacag ctatgtataa accaccctga
    21601 taaaaatttc aggacaaata cacatagctg tttcttttta ttgtattcct tcagcaatcc
    21661 aacgagattt atagcgaaag tcttttaaca actcttcttt tgtccaatta tttgcaatga
    21721 gatccgtcaa agtgttcatt acgagggtca tggaaaagta taggaaacta actgcttctt
    21781 ccgacgattg aatggagaaa tgattgattc ttaataattc cagccatttt tcgttcattg
    21841 gagaatcagc cgatagttct ctacgtttgg ttgtctgctg atcatttcgc tgggttaaca
    21901 agtataacct ttgccaatag atactttcgt gatctaagtc gcagcaccac tctaaatatt
    21961 tttcgatccc caaaaagaaa tgttgtttgt tttcgctaat gaattttaag atatcttgat
    22021 ggactatgtg agaactgctt ttgatcgtat acaaataagc atcttccaaa tcttgaaaat
    22081 atttataaaa agcaccgcgc gacatcccca tcttgtcaac gatttctgag actttgactt
    22141 ggctgatgtg ctgtgagcaa aatatctcca gtaataggtc atcgattctc tgtttctttg
    22201 cgttcgataa attgaaaaaa gtttcttttg gcatccacat ctctccttta tctctgatta
    22261 tacgtggata gcccttcatt gtcatgaagg attcattcct tctttttctc ttcttctgtc
    22321 aagtacccat cttccattcg ataaacgcga tcactccatt gaatcatacg gacatcatga
    22381 gtaaccataa tagtcgcttt ttgtttctca tgagcttctt taactagtaa tttgacgact
    22441 tcatatgcat gatctgtatc caaactagct gttggttcgt ctgctaagat caagcttggc
    22501 tcattatata aagcgcgagc aattgccact ctctgtcttt ctccaccaga aaggtcttta
    22561 ggataactat ttttaagtga ctggatatct aaagattgca gcaaggaatc gatttttgtt
    22621 gaatcttctt tttttgaagt aacttggtca actagttcaa attgttcctt taccgttaaa
    22681 aaaggaatca aattagagct ttggagaata aatcctattt ctttaaagcg taaatctgct
    22741 cgtttttttt ctggaagctc agttagtgag tgaccgttga tcactatttc tccggaagtc
    22801 ggtgtttgca atcctcctga aatggtaagg aaagtacttt tacctgaacc agaaggacca
    22861 atgatgctga cgaattctcc ttcctttaca taaaaatcaa ttgctttcaa agctgagacc
    22921 tttgtatgac cagaaccaaa tgttttggta acttttttca tcgttaatat ttttttcatt
    22981 tttattaacc tcctattgct gtaattgggt ctactttggt tatcgtacgt atcgaaaaca
    23041 atccgcctag cattgcgaca atgatcaaaa tcccactata tagcaaccat tgtgaccaaa
    23101 aaacagcaaa aggcatcgcg cttggtaaaa tcagactagt caaataagca aacaaaagag
    23161 caagcagaac gcctaccacc ccaacaataa aggactgtgc tactaaagat ttagcgatga
    23221 agaaattttt gatcccttgt gctttcatta ctccaaaaat agcagtcttc tgaagtgtca
    23281 tcacgtacat gaaaataccg accacggcag caaccactaa gaacaaaaag tatatcatcg
    23341 catttaaggt catattttgg gcagaatagc caggaatact ttcaatgaat gtcccaatag
    23401 ttaataactg tagacccttc gatgcttttt ctttcgaaat tttagctgaa tcctttatta
    23461 cgatcccatt gatcggctgt tcttcttcag aagcaaacgg ctgttgtcca tacttcaaag
    23521 cagtccacgt atctagggac gcatagatga cgggagaaac tgtgtaataa gtttcaggaa
    23581 agataccgac aatcgtcaaa ggatcgtcgt aactgccaat tttgatcgta tctccaattt
    23641 tatagcctga atcagccaga ttttgagaga tgatgatttc attctttgtt ttaaattcat
    23701 gccctttcgt gagttttggt aataaaaatg cttctttcgt tgtgccgaaa actgtaacat
    23761 tttctttgtt ttttcctttg attgctccgc tgtacaatcc gattggtgct ttctctcctc
    23821 cttcaatgta tttcagatct cctcttgtta attgtgaagc tgcaaatact tgatttgcat
    23881 cctccgacaa aacaatctct tgtgcgtccc aatcatcgat tgctttttta aactcttctg
    23941 aaagtccatt cgctagtcct gacaacatga atacgacata cgcaatcaag aacataatac
    24001 cgacgatcaa gccatatcgt aatttagaat agcgaatttc tttgatagct agaaacattt
    24061 gtttttcctc cctatgatag attgatagtg acaaaatgtc acttgttgaa tagtgtaact
    24121 ctaaagtgac aatttgtcac ttgtgttgtt tttttcttat caataaattg tctaagacat
    24181 ctttcgataa aaccttaaca tgagtcataa aaaatttatt taagccttat ttatgctttc
    24241 catgataaac taaagtgacc aaatcaatga ggtgggaaaa tgattaaact attagtagta
    24301 gaagacgata aagtattatc caataatata aaagaaatac tcgctgcaat cggcgagata
    24361 acacaagttt atgatggtag tgaaggactg ttcgagttgg aaagtggagt ttatgatctt
    24421 gcaatcttgg atttgatgat gccggaaatg aatggatatg aagtgttagc aaaaatacgg
    24481 aaagaaaaaa tacagactcc agtattgatt ttgactgcaa aagatagttt ggaagataag
    24541 attgaaggat ttgaacgagg tgcagatgat tatctaacaa aacctttcta tcgagaagaa
    24601 ctgatcatgc gcgtgaaagc attattgaaa cgctcgctag gtctctttga tgaaaatgtt
    24661 ctgaagtata aggatatcag ttgtgattta aaaagcaatg aagtcttgta taaagaacaa
    24721 gttttgccca tacaaggaaa agagtttgaa ttgctcgttt attttttaca aaataaggga
    24781 atcattttga caaaagagca gatatttgac cggatctggg gatttgattc tgatacgacg
    24841 attacagtta ttgaagttta tatgagcaac ttacgaaaac atctgcgaag tactggattg
    24901 gataaagaaa tcaaaacctt acgtaatgtc ggttatatac tgcaaagggt gtgatgcaat
    24961 gaatggagat attacacgaa agcaacgtag tcgctttttt gcgacaaatg tagcagcatt
    25021 tgcttttatc ttttttcttt tgggattcat tactttacag atattaaacc aatctgcata
    25081 cagagaaaca gatctgtcat tagagaaaat aaattttgat tctcgaacag tacaattaga
    25141 gatacaaaga tatcagcaag gcgatccctt tttaaacccg actcaaacgg aacaaaacag
    25201 aacaaacatg gaacagccat taatggaacc atcaaatgac cgttttaaca ctcaagtgat
    25261 cttgtggtct aaaaatggtg agatattgaa taaagcagct attggtgggc gtttcaacca
    25321 aatcaaagaa ttaaaaatgg atacgaaaaa tctgaatacc atccaaaata ttgaattaaa
    25381 tgaagacagt ggctcatctg ccctctcttt ccgttcgatt acgaaaaaag cggagacgaa
    25441 tcaagatggc gttgcctaca tccaaatttt agaaaataca aatcaaatca agaattcatt
    25501 agcgactttt cgcacgatta tgattttgtg tatgattgtt ttttggattc tctctattgg
    25561 tatcagttat tacttgtcta gtctaagcat gcgccctatt attctttctt ggagaagaca
    25621 aaaagaattt gttgagaatg cttctcatga attgcgcaca ccgttaacga ttattcaaaa
    25681 tagtttggaa catcttttta ccaagcctaa tcatactatt attgaagaat ccgaaagcat
    25741 cgctcaagca ttgtcagaga cgaggcgcct cactggattg acttcggatt tgctgacaat
    25801 cgctcggaat gattctgatc agcagctgct ttcaaagcaa atgatcaata cacaagaata
    25861 tatcgaacaa cttgttaaac catttcaaga gatggccatc atagatggaa aagagtttat
    25921 tctccataac gatgcaacat tagaagtacc aattgatgaa aaaaaaatcc atcaagtttt
    25981 ggttattttg ctggataatg cattaaaata tacgaatcca gaagataaga tcattttgga
    26041 ttcatctgtt aaccataaag aatggctgat tcacgtaaag aatactggcc cttctatcag
    26101 tgaagaagat caagcaagga tttttgatcg attttatcgg gaagatcaat ctcgggcgaa
    26161 agagactggc ggatacgggc ttggcttggc aattgcaaaa caggtaatcg aacagcatca
    26221 tggacagatt tctgtatcca attatcttcc acaaggagtc gattttaaag tccaattgcc
    26281 gttgaagcct aaaaaataat gcttatccct aaaaaagggc tgtgacaaaa atcttgtcac
    26341 agcccttttt tgttgcgaat aaacggtgtt ccagaagtag cttcttcgga aataagccga
    26401 aatttcttta agctgaccac ttctgtcaca acctctttag cttacgctta cgatttttta
    26461 ttgcggtctt caatgtgtac atcaccgctt gtgtcaatat ccaattcttc tcggctaaca
    26521 tcttctgtca ctttttcaac atcttcatgt tcttctttat gaatcccaac ttcttcacga
    26581 ataactgtat gtttgcttac atctacttgc tcttctttga ttgggatagt aatcgtgtca
    26641 tcttccaatt tttcgtctgt tccctgtgaa gattgatctg ttactggttt gcgttcgatg
    26701 acgatttctt cacgtttgac cggtacttct accgtttcag tatcgttgac cacatgtttg
    26761 tggatgtcga cttctccagt tgtcacatca tgtgtattta catctaattt ttcttctttt
    26821 agttgaattg tatcatcatc tagatttggt ttgcgatcga tgtcttcagt cttgcttgta
    26881 cccattgtat cagtctcgcc aggtacgtcc atcggatcag ttcctggtgt catattcaat
    26941 ggatccgttg tattttgaaa gcctgtcgtg ccacctacgt ccattggatc tgttccagtg
    27001 ccagtttcta atccagtccc cattgtgctt gctgggctaa cagtatcttg tgtatccatt
    27061 gtatcttctg ttgtttctgg ctgacgatag ccttttactg tgatgacaaa ttttccatca
    27121 gaaatatctc ctctatattg atataaagga tcattttctg gtgtagccgt ctcagaatca
    27181 taggtatcaa aagaaaaagt atcttttatt ttttcccata aagaacggtc ttcttcacca
    27241 tccatccgat tttcatctgt ttcaacatct ataccagaca atccgtcaaa tcctagtcta
    27301 gatgctgctt catcagtagt ataaataacg atatcatctc gttcataccc ttcgttacgc
    27361 aaccgttcaa ttactgataa tgcttcttcc ctcgtactat agcttccgat gaccgttaaa
    27421 tttttctctt ccatgtaaat tcctcctagc aaatagattt atgattggta tattgttact
    27481 tata
//
LOCUS       DAFLWQ010000034        26160 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.035, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000034 DAFLWQ010000000
VERSION     DAFLWQ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26160
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.035"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(62..1093)
                     /gene="queA"
                     /locus_tag="L1V16_001451"
     CDS             complement(62..1093)
                     /gene="queA"
                     /locus_tag="L1V16_001451"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBN1275797.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            1286..2461
                     /locus_tag="L1V16_001452"
     CDS             1286..2461
                     /locus_tag="L1V16_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HBN1275798.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            2465..3106
                     /locus_tag="L1V16_001453"
     CDS             2465..3106
                     /locus_tag="L1V16_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1275799.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            3103..4020
                     /locus_tag="L1V16_001454"
     CDS             3103..4020
                     /locus_tag="L1V16_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1275800.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            4017..4688
                     /locus_tag="L1V16_001455"
     CDS             4017..4688
                     /locus_tag="L1V16_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1275801.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(5229..5717)
                     /locus_tag="L1V16_001456"
     CDS             complement(5229..5717)
                     /locus_tag="L1V16_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HBN1275802.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(5918..6184)
                     /locus_tag="L1V16_001457"
     CDS             complement(5918..6184)
                     /locus_tag="L1V16_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBN1275803.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(6184..6447)
                     /locus_tag="L1V16_001458"
     CDS             complement(6184..6447)
                     /locus_tag="L1V16_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBN1275804.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            6923..7108
                     /locus_tag="L1V16_001459"
     CDS             6923..7108
                     /locus_tag="L1V16_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBN1275805.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(7250..9073)
                     /locus_tag="L1V16_001460"
     CDS             complement(7250..9073)
                     /locus_tag="L1V16_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HBN1275806.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(9671..12376)
                     /locus_tag="L1V16_001461"
     CDS             complement(9671..12376)
                     /locus_tag="L1V16_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBN1275807.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(12682..13629)
                     /locus_tag="L1V16_001462"
     CDS             complement(12682..13629)
                     /locus_tag="L1V16_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HBN1275808.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            13819..14088
                     /gene="rpsN"
                     /locus_tag="L1V16_001463"
     CDS             13819..14088
                     /gene="rpsN"
                     /locus_tag="L1V16_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBN1275809.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(14264..14626)
                     /locus_tag="L1V16_001464"
     CDS             complement(14264..14626)
                     /locus_tag="L1V16_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBN1275810.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(14637..15758)
                     /locus_tag="L1V16_001465"
     CDS             complement(14637..15758)
                     /locus_tag="L1V16_001465"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBN1275811.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(15774..16124)
                     /locus_tag="L1V16_001466"
     CDS             complement(15774..16124)
                     /locus_tag="L1V16_001466"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBN1275812.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(16254..17765)
                     /locus_tag="L1V16_001467"
     CDS             complement(16254..17765)
                     /locus_tag="L1V16_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBN1275813.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(18087..19439)
                     /locus_tag="L1V16_001468"
     CDS             complement(18087..19439)
                     /locus_tag="L1V16_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBN1275814.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYLEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(19592..20668)
                     /locus_tag="L1V16_001469"
     CDS             complement(19592..20668)
                     /locus_tag="L1V16_001469"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBN1275815.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            20864..22609
                     /locus_tag="L1V16_001470"
     CDS             20864..22609
                     /locus_tag="L1V16_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBN1275816.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(22889..23326)
                     /locus_tag="L1V16_001471"
     CDS             complement(22889..23326)
                     /locus_tag="L1V16_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBN1275817.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(23310..24683)
                     /locus_tag="L1V16_001472"
     CDS             complement(23310..24683)
                     /locus_tag="L1V16_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275818.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(25005..25493)
                     /locus_tag="L1V16_001473"
     CDS             complement(25005..25493)
                     /locus_tag="L1V16_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1275819.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(25515..26117)
                     /locus_tag="L1V16_001474"
     CDS             complement(25515..26117)
                     /locus_tag="L1V16_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBN1275820.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         7503 a         5561 c         4838 g         8258 t
ORIGIN      
        1 ctttgtcata aaatctttgt aaagcttttt tgttattcaa aactagcggc ttttcataac
       61 cttatttcac gaacatcgca tctccaaaac taaagaaacg atagcgctct tcaatcgcat
      121 gctggtaagc agataaagtc aattctcttc ctgcaaaggc actaactaac atgactaaag
      181 tcgattttgg caaatggaaa ttagttgaga aagcttctac cactttgaat tcatagccag
      241 gcgtaatgaa aatatcagtc catccgctgt ctgctttgat ttctccatta aatttcgttc
      301 caatcgtttc taatgttcga attgaagttg ttccgacagc cacgattttc ccgccatttt
      361 tacgtacttg gttcaatcgc tcagccgctt cttccgtcaa acggtagaat tcactatgca
      421 tatggtgttc ttcaatttta tctacgctga caggtcggaa tgtacctaac cctacatgta
      481 gtgtcagata gactaattca acaccctttg cttcgatctc atcaagtaat tctttcgtaa
      541 aatgcaatcc agctgttggc gctgcagcag aaccattttc tttcgcatag acagtttgat
      601 agcgatctgg gtcttccaga cgttctttga tatatggagg caatggcatt tctcccaatg
      661 attcaagaat ctctagaaaa attccttcat actcaaagtc aatgatccgt ccgccgtgtt
      721 ccaattcttc tttcactact gcttgcaatc tgccatcacc aaaagagatt cttgtcccaa
      781 ctttggcacg tttcgcaggt ttgatcaatg tctcccacgt atctccttgt gtattcgtta
      841 gaagaaggac ttctaaatgc gcaccagtat ctggtttttc tccatataaa cgagcaggca
      901 gaactcgtgt attattcata actagcgcat caccaggctg taactcttca atgatttcat
      961 ggaaatgttt atcttccatc tctccagttt tccgatccaa aacaagtaaa cgagaatgat
     1021 cgcggtcttt taatggtgtt tgtgcgatta attcttccgg caagtcaaaa tcaaaatctt
     1081 ctgttgttaa catatcgtca ctcactttct atcatgtgct tcatcattct atcatgtttt
     1141 tcgttctgtt ggcaaaatca gcactttttc acttctattt tttgttttcc taaataaaaa
     1201 aactacccta tttgtatttt ttcattgttt taggcatact agtaatagat agttcttcat
     1261 tgaaaataga aaaagaggtg gcaccatgat tgaatttcaa aatgtgtcaa aaatttataa
     1321 aggtggaaaa gtcgctgtag aggacgtcaa tctttcattt gaaaagggtg agttcatttg
     1381 ttttatcggt acgagcggaa gcggaaaaac gacgacgatg cggatgatca accgaatgac
     1441 tgatccaaca caagggaaaa ttttgattga tggaaaatcc atccaagaaa ttgatccagt
     1501 ggaattgcga cgtcagatcg gctatgttat ccaaagtatt ggattgatgc ctcacatgac
     1561 gatccgtgaa aatatcactc ttgtccaaaa attgttgaaa gtcagtcaag aagaacggaa
     1621 taaaacagct gaaaaaatga ttgatcttgt ggaattgccc cgtgagatgt tagatcgcta
     1681 cccacatgaa ttatctggtg gtcagcagca gcgtattgga gtcgttcgtg cccttgcagc
     1741 gaatcaagat atcatcttga tggacgagcc attcggtgcg cttgatccaa tcactcgtga
     1801 ttccttgcaa gaccttgtca aagatttaca agagcgtttg ggaaaaacga tcgtatttgt
     1861 aacccatgac atggatgaag cgattaaact agcaagccgt atcgccatca tgagtgaagg
     1921 ccgtgtgatc caatttgata caccagaaaa tattttacgt catcctgcaa acgatttcgt
     1981 agaagagttg attggagaag atcgcctact acaagccaag ccaaatgcga caagagtcgg
     2041 cgaagttatg ctaaatacag caatcacgat tacaccggaa aaatcattac aagaagcaat
     2101 caaactgatg agggaaaaac gtgtagatac gttgttagtt accgataatt cgaatgtatt
     2161 aaaaggattt atcgatgtag aaacgttgaa taaaaaacga ggaaaagtat ccagtgtcgg
     2221 cgacattttg aataaacatg ttttttacgt aaaagaatcc gcctatcttc gtgatacctt
     2281 gcaacgcatt ttaaaacgcg ggctgaaata cgtgccggtc gttgatgaac agaacaaagt
     2341 cgtaggtatc ctgactcgtg catcattagt ggatatcgtc tacgatgtga tttggggaga
     2401 agatcccgca actactgatg ttgcagagtc agctactcct gaagaatcta aggaggtctg
     2461 acctatgcag cagttttttc atcagcacgg ttcagaaatt ctctcaaaag gttttgaaca
     2521 tctttatatt tcaggacttg ctttgatcat tggtatcatc attgctgtac cgcttggtgt
     2581 cttactgaca cgttttccaa aagctgccac gattgtgatt ggcttaacca gtgccttgca
     2641 gacaatccct tctcttgctt tattggcatt gatgatcccg ctatttggcg taggtaaatt
     2701 acctgcgatt atcgcactct ttatttattc attattgccg attttacgta atacgtacat
     2761 tgggatgaaa aatgtcgatt ggaattatcg ggatgtggca aaaggcatgg ggatgactga
     2821 gttccaatcc attttttccg ttgaattgcc cattgctatg ccaacgatca tggctggtat
     2881 tcgtttagct gccgtttacg tgattgcatg ggctacactt gcctcttata tcggcgctgg
     2941 tggtttaggc gatttgattt ttagtggact gaataattac caaccagatc tcattttggc
     3001 aggtacgatc cctgtaacaa ttttagcact attggctgat tggcttctag gtctcttgga
     3061 acaccggctg acaccgatcg cacttagaga ggagaatgaa gaatgaaacg tatactaaaa
     3121 atgaccatgg ttcttttctc tcttcttata cttgcgagtt gttccttccc tggtcttgcc
     3181 agcaatacag atgaagacac catttcgatc acaggtggaa tcacttcaga agcacagatc
     3241 ttagcaagtc tagttgccgg aatggttgaa cattatacag ataaaaatac cgcaatcatc
     3301 aacaatctgg ctactacaac tatcaaccat caagcgatga tgaacggaga tgcttcaatt
     3361 tcagcggctc gctacacagg aacagattta acgactacat tgaaccttcc tcctgaaaaa
     3421 gatccgaaaa aagcgtttgc taccgtgaaa gatgaatttg agaaaagata cggtcaaacg
     3481 tggttcccgt cctatggttt tgaaaatacg tatgtctttc ttgttcgaaa agacaccgca
     3541 caaaaatacc atctatctaa agtcagcgat ctgaaaaatg tagcggatga attagtagct
     3601 ggtgtagata cttcttggat caatcgtaaa ggagacggtt atgacggctt ccaagaaact
     3661 tatggcttct ccttcaattc gatattacct atgcagattg gacttgttta tgacgcagtc
     3721 gaagcaggaa aaatggatat tgttcttggc tactctacgg atggacggat cgccagttat
     3781 gatctagtca tgttggaaga tgatcgtcaa ttcttcccac catatgatgc tgctccagtt
     3841 gtagacaaca agatattagc tgatacgcct catttaaaag aagccttaaa taagttaggt
     3901 cataccatca gtacggaaaa aatgcaggaa ttgaactacg aagcagataa taatctagtg
     3961 gaaccatcag tagtagcaca acgtttctta caagaaaacc actattttga agggaagtga
     4021 agcaattgga taaaatgaat gtctttcaac aatttttcta ttatttccag gaaaatggct
     4081 cctatatctt tgcacaattt atccgtcact tcctgatttc tatctatggt gtcctctttg
     4141 cagcagttgt cgggattccg gttgggatca tgatttctag gagacgtaaa ttagcaaact
     4201 gggtgattcg tttggcgaat atcatccaga cgatcccttc tctagccatg atctccattt
     4261 taatcattgg attaggcctg ggagtcaatg tcgtgattgt tactgtattt ttgtattccc
     4321 tcttaccgat catcaagaat acgtataccg ggatgatcca agtagacaaa aacatccttg
     4381 atgtcggcaa aggcatgggg atgactgcta gacaacgact attcatggta gagttaccac
     4441 tctctgtttc tgttatcatg gcaggcataa gaaacgcgtt agttgttgcc atcgggataa
     4501 ccgcgatcgg tgcattcgtc ggtgctggtg gtcttggaga tatcattatc cgaggaacca
     4561 atgcaacaga gggcacatcg attattttag caggtgcatt gccaactgca ttaatggcga
     4621 tcatcacgga ctggctttta ggtattttgg aaagacggct agatccagcc agccgtacat
     4681 cacgctgatg ttattgtaaa aaacaaaagc ttctgcgacc atttgttggt cgcaaaggct
     4741 tttttagttc tgtcattttt aaggcaataa tccactctga ttcttccctc cttatgggca
     4801 aagagttgct tttcttagct atttatccat tccgtatact ccaacttcat actgccaacg
     4861 ggttcatatc tgcatccacc gactaagttt ttttcttatc cgctaaggca ttttgccaat
     4921 ccattttccc atcactcgtc atggaattca taccacatga tctctaaata ctcgtctgct
     4981 tgttctttga attgggcatc aattcttaca tcctttggcg tggctttcat ttaagccttt
     5041 tccatcagtc ctcgattgtt cgatgccttc agctgcatca tcaaaactgg tgactgccgt
     5101 atcggtaact tcgatcatct tttatacaat cgggaacttg ccatcctcat ccttggctaa
     5161 aaacatatct agccattcca gcttctcgcc atgggaggtt tgcggttcct aaaaccggta
     5221 cacgattctt atggactgca tccgtcgcaa ctagacttgg cgatacgatg atccttcacc
     5281 agaagagcac ccccgtaaac caattgatcg atatattgcc aataagaaaa gacattggcg
     5341 taaaagatat cgatccctcg tgatgcattg ccgttgatac tgctattcat ggccgaaagc
     5401 gccacgactt taacttcttc cgtttgagtg acattcatgt tcggcaatgt cgctttggat
     5461 acccgctctg ctaaaggaac gacactggta ttgtatttcg tatctgtatc ttttccaaaa
     5521 gaccatgcca acgaatcctc tgggaaccaa taagacgact ccggttgatt gtccattgct
     5581 tttttcaaca tacttttggc tgtttctcga taaacgacat ttccaattgt cttcgcctca
     5641 ctttggcgat aatcgatggt cgttgccact gccaacacta acaacgatgc tccaatttta
     5701 ctgattttcc ttgtcacact tcttcctcct tgttttacat aaacccgtca acattccatt
     5761 cctaaactca aacaatgacc cttcaaaggt ggagatatag gaacaaatta aagaaatcat
     5821 gcaataaatc caagaaggtt ggttttagaa caaaaaaaga gtctcctttt tggggagact
     5881 ctttgttaac tatctaaaaa ggttggctct tctcacttca ctcataatgt gtccaggcag
     5941 aataaatttc tacaacttta ttttcctcat caactttgta aaccactcga tgctgtctat
     6001 tcagcctgcg tgagtatctg ccttcatgtg taggtctcag cttttcaaaa gactgcgtgg
     6061 gcatatatgg atcttccttc aatgtctgaa tcacttcttc aaattgtttc tttaaattcg
     6121 tttgcttgat ttttcttaaa tccactttcg cagagttttt gattgcgact gtatagttac
     6181 tcatcaaaga gcttcccaat caatatcatc gatattcgta aagctactgt cgtctttttc
     6241 gcggtctcgt actttatcta aagtacctgt ttgctcaaga aaaagggttt cttgaatcgc
     6301 tctccagtct tccagcccaa tcaatacagc attgtttcca ctacgatcac taataatctc
     6361 gatttcagta tgattttcat ttacctcttt caataactga taaaaatttt tacgagcagt
     6421 gctaggattc atcgttgtat tagccattgt ctctcctcct ttttctgata taattatagc
     6481 gtacttgatt aagtacgtca aaaaaataca ataaagcact taaattcagc aaacttttcc
     6541 tcttttttac atagagaaaa agaccccttt ttagggagga tctttgtcca cgctcacttc
     6601 ttactccttt acgactagcg gtagccaaac gtaaagtaat tggtaacaac gtatcatctt
     6661 tagcaaaggt cgaatccaaa gcctgtgagt ctatgcaaca acaccaatac acgaaggttc
     6721 ctcgttgcag tgtgacttga ttgatatctt gaataacctg aggatacgca cgaaagattt
     6781 gtaacggtta ttcaaaactg attttggccg tcaagtcttc tactgcctca aaaatgattg
     6841 cctctttcgt ctcctgtcat tcatgttcac tatcgatttg atacttgctt agaccgttgg
     6901 gtttgtgaat caccaattaa aaatggcact gagttatggt aacaaaaaat ggtcacttga
     6961 cgaggctgag attcctactt atgaagacac atggcactta agagtcgagg taaaggaaga
     7021 agctgaaaat ataggaggct gtacattatt tggcaaagga ttcggaaatt atgatcaaga
     7081 catcaaaatc aaaatgtttt acagctaaat aggaagaata ataacatttc atacgctgtt
     7141 cccatcttta atggcttata gagggcacct ttagctgaga ataagacaaa acagaccctc
     7201 tagcttcaat taagagctag agggtctgtt tttgatttta aaacttggtt tatttcttca
     7261 aatggtagct ataggtgctg acaacgatat tttcacgcca agacaatcgc aatcttaacc
     7321 gcaaacttgt ttggttatgg agaatattct gccagcgtct gtttggtaca aattgaggaa
     7381 tcaacacagt agttgtatag ttttgtttcg ctgcattttt acttacgata tctacataac
     7441 ggataattgg attttcaatc gagcgataag aagagtggac gattgaaaaa cggacatctg
     7501 ggaaatgctt tttaaattct gcttcgattt ctttttcttt ttcgacatct tcgtctagcg
     7561 aaacatgcat cgcaacgaca taatcaccga tcgaacgtgc gtaattcaac gcaccgatat
     7621 ttacccgtgt cacattcccg actaatacaa gaacggtatt cccgtcataa tcatgtagtt
     7681 ttgcatcatt ttctaaacga agctgttctg ctactttttt ataatgatca tggatcttat
     7741 aaaaaatgaa cataacgatt ggcataatga tgaagaaagg ccaaatgtcc cctaaccgat
     7801 agacaaacaa aatcgcaatg attgcatatg agatgaacgc acccgtaata ttggcaatcg
     7861 atttgcttaa ccatcttttt ccttcttttt tccatttgac gaccatccct gtttgagata
     7921 aagcaaatgg aatgaacacg ccgatagagt ataacggaat caagcgttct gttgagccat
     7981 ggaaaataaa cagcaatacg atcgaaccta gcgctagtgt gataatccca ttggaatagc
     8041 ctagtcgatc cccacgatct tgatacatgt gaggcatgaa tttatctttt gccagattgt
     8101 atgcaagaac tggaaaagca gaaaaaccgg tgttagcagc aactgctaaa atcagcgctg
     8161 tagcaaattg aaggacgtaa tacaaaatac catgtccaaa gacagcttta ccaatttgag
     8221 acaaaacagt gacttctttt tcaggaacga tcccatacca atagttgata aatgtgatcc
     8281 ccacgaagaa gaaacctaag atcaatgcca tcatcgtcaa tgtagcagcg gcattttttg
     8341 ctcttggctt cttaaagaat ggtacagcat tactaatcgc ctccacccca gttaaagagg
     8401 aagaaccaga agaaaatgct cgtaaaatca aagcgataga aacacccggc acagccgctc
     8461 ctggaagtgc agtagcttgc aatggcacag cacctgtcac gatattatat aaaccaacaa
     8521 cgatcagtaa cgagatcaca aggataaatg tgtacaccgg aaataatagg aacgatgcag
     8581 attccctcag cccacgaaga ttcagcatca tcagtagcaa aacgattgtc acagaaatag
     8641 cgacttgatg accgtagagt gctggcaccg ctgatgtgat cgcttcagca cctgctgaga
     8701 cagatactgc tactgtcaac atgtagtcga tcaataaaga gccaccggaa atcaagccag
     8761 cattctttcc aagattctca ctgctgacga catatgctcc cccgccatga ggataagcat
     8821 ggatgatttg acgatatgat agcgttaatg aaatcaataa aataataaca aaagcggcaa
     8881 tgggtagcga ataccagatg gctgcagcag acaaagcgac taaaacgaca acgatttgtt
     8941 ccgtaccata tgcaatagat gataacgcat cagacgacaa taatgccaaa gcagcaaatc
     9001 gggttaattt gtgctcatca ttttcagcag attttaaagg cttacctact aacaaccttt
     9061 ttaagtaatc caatttctaa actcctttac acacaatttt acttcaagtt ttatagtcga
     9121 aaatttatag taaacaagat gttatagtac gctcactgac cttaaaagtc aataaacttt
     9181 aagaaaataa ttggaaaaaa acagaaaaat atcaagcgct ttttcaaacg ctttaataca
     9241 gcaaaaatct aacatttttt tatgggcttt ttctttgaat tctataataa aaggatagaa
     9301 cttgacttag aaaatcaagt tctatccttt ttgatatctt aacttttgga agagagatgt
     9361 aaggctgctt tctacccatc attcttacta ctcgaagcat agcgcagttg tcacaacctc
     9421 ttgataaacg gtgtttaaaa gcttgcatct gcggtaataa gcccaaccaa attaaaaaca
     9481 taagaagctg tttttatttg gtcgttctta ttacttgatg cagagcagct tttttacaac
     9541 ctcttggtac acggtgttca atcagctgac cctcggtatt agctcaaaaa aacggcaaaa
     9601 tatgaggaac tatttttcca tttttttctc taatactcag gtcaaaacac tgatttcaca
     9661 acctcttttt ttaatgaaaa atatggctct catgcgccgc ttctttgaat ttcgtcattt
     9721 tttcttcgat gaacggatag attgccgttc ctacgattcc aaagacaaca aacaaaccga
     9781 tcatgatcca gattgctttc gtagcatttg gccaataaat tcctcctgca gattcccgta
     9841 acaagtttac cgcatgagta aatggcaaga acggattgat catttggaag aatttccctg
     9901 agacttggat cggatagttc ccgcctccgc cagagatcga cagtactaag atgataatag
     9961 cgatcccttt accgacatta tcgaataatg cagccaagac atagacgatc atcatgaacg
    10021 ctaaggcgat caagacagca aatgacacgc tgtagaccgg attttggaca tctactccta
    10081 gtaagaaaat attccctaat gtaacgatca agctttgcgc aatcgccatt gtcaaaaatg
    10141 tcagcatacg agcaacgaat tgttctcgtt tcgtaaaatt gtttcggtct ttctttccta
    10201 aatagtattc tgtcgtagca acacttgaaa gaagaacagc gccgacccac agacatagtg
    10261 cagtataaaa cggggtgcta gctgaaccgt tatttgcgat tggataaagc gcattggttt
    10321 gtagctcaac aggttgtgta aagaagtcac tttcttttgt tgcgtctagt ttcaataatt
    10381 tgatgacttc gcctagatcg acttcttgtt cgccttttcg gatcgcgtct gctgcttttt
    10441 ggataccagc tttgatattt ggccagtcat tgttgatcaa gtccgcagca gcgttcacag
    10501 ctgtttcgac ttctggcatt ttttcattta ctgttgtcaa tgtaccggtg atttcatttt
    10561 ttagtgctgg ccaatcattt tggataaaat cagcggccaa tcctaatttt tgctgaatga
    10621 tcggtaattc attgttgtat aggtctgccc cttcattgat gccattgacg atggtatcca
    10681 tatttccatt cagcattgta ttggcatcat ggatttcttg tccaattgca ggcatttctt
    10741 tttgatattt ttctaaaatt gccactgcat tcgttacagt tgctttcgtt gagctgagaa
    10801 gcgaatcaaa gtcgatctgg tccgctttgc tcagtgcgcc ttgtgcagtc ccaatcgtat
    10861 cgatgacttg gtctagtaga gaagtgacag tggaactgat ttgacctgta ttgataccag
    10921 caatgatgcc attgatatta ttaacaacgg catcaatttg atctagcaat tcatcaatag
    10981 ccttcgtgtc ttcattttga acagctgtgt tcaaagcaga taggcggttt tgcagattgc
    11041 ttagcaaggg ttttaattga tttagctgat caataattgg ctgtaatttc gtatttccag
    11101 cacttgtttg caatttagtc aggaactcga ccagtttatc gattgcattt tgttgttgag
    11161 atattccgtc aataaagccg ttcaatacat tgctgatgtt tttcttttca tcatcagtca
    11221 gcttaccatc ttcaatagct gttcttacag tatctattaa cgaacctgtc gttgttgcca
    11281 cttgtccaat tgacttcaat gtaacatcta cactgtttgt gatgcttggt atcgcatctt
    11341 tcagctgaga ggcacctgat tttgtttggt ttgctagatc acttgcctga ttttctaaat
    11401 ttttcacatc tggcaagata tcttgtactt gttggatgat cgtcaagcct tgttttgctt
    11461 catcgattcc ttggttcatt gtctcttgga tcgaagcaaa atcgccgtcg atctctgcta
    11521 gttgcttacc ggcattttgg atctctggga ttttttcttg caaatcaagg atgatttttg
    11581 cttgatcttt caactcaggc attttgtcat tcaatgcaac gactttttca cccatctcat
    11641 ctactttagg gatgtaatcc acgaattcat ttgctttatt cagtttttcc ttgatttcag
    11701 gtagttgact ttgtaattcg aggacttgtt ttgtgtagcc gtcgatcgtg tccaaatttt
    11761 catctgttga taaaatcata tctttaactt tattgatact tactaggttc gtatcgatgt
    11821 cgtaacctat ctcattgaat actttcaata aagtcgaact ggctgttttg ataaattcat
    11881 ttgtgatttg cgattggatc gaacttgctc ctttatcggt gattttcggt gcaatcgcat
    11941 tgattttttc atttaccgta tattcgattt ttggtttctt gatatcacca ctagtaaaac
    12001 tcagcagatc ttctgagaaa tcctttggca agtaaatacc tgcgtaatac tttccggaac
    12061 ggactccgtc ttctaattgt tcttttgaat caacgaattg ccatcctaat tgtttatttt
    12121 tatgaagcga ttcgatgact tgctccccaa tggccacttc tttaccttga aactctgctg
    12181 gcttgtctgc actgtaaaca gcaattggca gctctccagt atttccatat ggatcccata
    12241 atgctttgat gttaaaccac gcatatagcg aagggatgat catgatcgcg atgatcagaa
    12301 gtgttgcaat cgggtttttg aaaatccgtt tccagtcaag caaatataat cgaagcgtat
    12361 ttttgattga ctgcatagtt ctcccccttc ttcttttttc agctgaatta ctttaccatg
    12421 tatttcatac ttttttcaat cggctttttt caaaaaagtc gaatttttgg acatatcacg
    12481 gcaattgtct cattgtaatc tcttacatat tgagaaataa ttaaggatta cagcctttac
    12541 tttatcatga aataaaaggg aaagataatt ttatgccaaa gtttttatct attatacgta
    12601 tacgcaaaaa agctaaaaca ttttttgtct ttgcccctac aaaaatgttt cagctttttt
    12661 cgttttttat tcctgtattt cttatttttc gaatgacagg atgattttcc cagcaggagg
    12721 atgtccttca actagctgat gtgcttggat gacatgctta agtgaagcag acagattcat
    12781 tgaaataaaa acatgaaagg ctcctttttg gtaggctttg attatgccag caaaggcttc
    12841 tgcatctaga tattcctttc ttggaacaaa cgattcataa aagccttcct ttttttgccg
    12901 caaatctaga tctgggaggt catttaatgc aacatacctg ccgcctggtt tcatgatctg
    12961 gatgccggtt tctcctttga tacttccttt cgtcgcatcg attacaaggt ctgcctgatc
    13021 agcaaattgc agacctggat ttgttttatc ataagcagca aatgctgaag ctcctaattt
    13081 ttttaccttt tcctcatttt tactggatgc actggttaag attcggattc ccttttcatg
    13141 gagaagctgg atcagacttg acccgaccgc acctgatgct cctagtatca ttacagtatc
    13201 tgtcggctgg atttccgtca aatggttgat tagattataa gccgtaattc ctggcgtgac
    13261 cattccggct gcttcttccc aactcatttt atctggaatt tttgctactt ttgctgatgg
    13321 caacacgact tcttctccgt aagtcccgcc gactgcatgg acagctactc gatcacctac
    13381 atgaacagtt gtgacatctg aaccaatctc tgtcacaata ccagcgccat cattacctgg
    13441 tacataaggg aatttcaatg ttcgtatctc tttcatttct cctaaacgca aggcaacatc
    13501 ataaggattc acactgaatg cttttatttc tacacgaaca tgtccagaac cgacttctct
    13561 gggatgagca tcgatttctt caaaaacatc ttgtgcttct ccgtaaccgt taattgcaaa
    13621 tcttcgcatg gtcaccatct ccctttttct ttaagtttac gtttatgcct ttattttgac
    13681 aaaaaaaatg tcttttcgtt ttggcgcatg attcaaaaca aaatagttgt cttttttcgc
    13741 gtaacgtgtt aaattattta tctaaaagcg taaagattac gatttacgct aataaaaaat
    13801 aattggagga atttgttgat ggctaaaaaa tcaaagattg ccaaagcaaa aaaacagcaa
    13861 gaaacgattg aacgctatgc tgctttacgc caggaattaa aagcgcaaaa agattacgaa
    13921 ggcttgcgta aacttccttt agatgctcgt ccagaacgat tgaaaaatcg tgatttaatc
    13981 gatggacgcc ctcgcggata catgcgtaaa ttcgggatgt cccgtataaa attccgtgaa
    14041 ttagcacata aaggtttgat tccaggagta aaaaaagcca gctggtaatc caagtctggc
    14101 tgtaatgtaa aggaggaggg cgcatggacc actccttgga tcatcaaaaa agatacgttc
    14161 gcttcttcta gcagaaatgc tggtactaga agcagacgta tcttttttta cgcacagctg
    14221 gtcctttttt atatgtaaag gctgcatggt tacttcgcta tatttattta gtaacaggag
    14281 tcagtgcttc gatacccaca ctaattttca atgctcggtc aacttctgcc ataatgggtc
    14341 gatccaaatg gcagaccttt tctttcaatc ttgatttatc gatcgttctg atctgctcca
    14401 acaggataac ggagtctctt tctattcctg ttccagtagc tttgatccca atgtgagtcg
    14461 gaagcttagg tttagccatt tttgccgtta tggccgcaac aatgatcgtc gggctaaaat
    14521 ggttacctag attattttga ataaccaaaa ctgggcgtgt tccgccttgc tccgatccca
    14581 cgactggaga aagatcagca aaataaatat ctcctctttt taccatagga tcctccttat
    14641 tcttgatatt ctcttggtat ccgctgtcct aatccgcaag ccacttcata gtggatcgta
    14701 cctaattgat ctgctatatc ctgcatagtg atttctttgt ctgcattttt gccgataagc
    14761 gtcacttttg ttccgacagg aaattcttga ggcaatcgga tcatcagttg atccatacat
    14821 acacgcccaa tcgtttcaca gtagttccct tctaccaata gagaaaaacc ctgcatcttt
    14881 cgtggccagc catctgcata accgatcggt atcgttccga tccactctgc ttcaggagtg
    14941 atatatgttt ctccatagcc gattccttca cctgctggga gttttttgac ttgaatcaat
    15001 tcagaaacca gctcaagtgc tggctgcaat ggataaactt ccggtagtgc gtgcccagag
    15061 ggattaagtc cgtacattgc tactccataa cgaatcatat tgccgattgt ttcatcatgc
    15121 cataaagccg ttgcactatt gctgacatgt acatatcgag gaagttcggg aagttttttc
    15181 agcacttcta taaagcgttc tttttgcaga ttccaatatg tatcatctgc ctgatctgct
    15241 gtagaaaaat gggtaaataa accttcccat tctaatacac gactttcttt gatgaatgca
    15301 gctgcctctt ttacttcttc aggtgtacaa aatccgatac gacccatccc agtgtctgct
    15361 tttagatgaa tcgaaagagg cgtctctagc ttacttttct ctaaaacagc agctgctgct
    15421 tgcaaccatt cccgtgtacc tgcagttact gataaatcat gagcaacagc tacagtcagt
    15481 gcgtcgtaag gaaccatatt caagataagg atgggctgag taaatccagc ttctctcaac
    15541 tcgactcctt catctaaatt tgaaacacaa aagcccgaag ctccacctgc aactgctgcc
    15601 tcagctgttt caatagctcc atgaccgtat ccgttcgctt ttactactgc aaacaattct
    15661 tttccttgcg gaagtcttgc aacttcattt gctacatttt cagttatagc ttttttatgt
    15721 atcactgctt tcgttgggcg gtgccaagcg acaaccatcg tttttccttc tttctagtct
    15781 tccaaaataa tttgtgcaaa agctgtttca tttgtatgag taatactgac ccatacattg
    15841 ccttcatgag gtgaacgcgt cacaacaggc tgaccatttt cattttttaa aatctcgaca
    15901 tcttgaaagg taacttttcc gatcccagtt ccccaagctt tagagaaagc ctctttgcaa
    15961 gcgtaacgcc cgcctaaaaa ttctacttgg cgatgaaaag gcaaggactg gaatagtttc
    16021 atttcatcag aggtcaagat tcgtgcaatg aattttggtt tttcttcgat cagccgagtg
    16081 atcctaggaa gttcgactgc atcgatccca attcctttta tcatatgctt ttctcttttc
    16141 aataaattta gaacactctc attctaccaa attataacca ttttgccaca aataagtcca
    16201 caaataacaa aaatgaaagt ttctcttaaa aaagagaaac tttcatttta tgtttaatcg
    16261 ttatttgaac ggattacaaa tccgcgtttt ttatcattgt gacgtttacc gccatctttt
    16321 tggctgttat tatttttgct ataaccgcct tttgatttgt ttccacgata attaccgccg
    16381 tcacgacgat tacggttgtt tccgccacca cgtttgccat ttttattgta tccttttttc
    16441 tgcattggca atgggcgttc tggtgtgatc ttcactggca ctgcatcagc tggatctttt
    16501 gctgtcgttt ttagcaaaag tgcaactaaa tcttgtgcag aatattcttc taataattta
    16561 tctgctgttt gcaggtattt atctagacca ttttctgcaa gttttgtttc gatttgttca
    16621 actgcagcac ctaattgacc tttgaatgct tctttttcgg ttggtggacg taaagtcgtc
    16681 atccgttttt tcgtcaagtt ttcaatcaca tgcaagtagt ccatttcatt tggtgtaacg
    16741 aaagtcacag acataccgcc ttttccggca cggcctgtac gtccgatacg gtgaacgtag
    16801 ctttctggat cttgagggat atcatagttg tacacatgag tgacacctga aatatctaat
    16861 ccacgtgcag caacgtctgt cgctacaagg atatctaaat gaccgctctt aaatgaacgc
    16921 aatacgctca ttcgtttttg ttgagacaaa tcgccatgga ttccttctgc acggtaaccg
    16981 cgtgcttcta atccgcgtgc caattcgtct acacggcgtt ttgtacgtcc gaagacgatt
    17041 gttaattcag gtgtttgaac atcaaacaag cgagtcatga tatcgaattt ttcgtattct
    17101 tttgcgcgga catagtattg atcgatcaag tcagctgtca tttctttcgc tttgatcttc
    17161 acatgatgtg gatttttcat gaatttaacg ccaatattct tgatagctgg cggcatcgtt
    17221 gctgagaaaa gtaatgtttg tctttgatca ggaacttgtg aaatgatttt ttcgatatct
    17281 tccaagaagc ccatattcaa catttcatct gcttcatcca aaactaatgt ttgaacggtt
    17341 ccaagtttca atgtgtggcg gttaatgtgg tcaagcatac gtcctggtgt acccacaacg
    17401 atatgtggac gatctttcaa gccacggatc tgacggccaa tatctgctcc gccgtaaacg
    17461 gcttgtacac gtactttttt gtcgcgccct aaacgatata attcttcttg tgtttggata
    17521 gctaattcac gtgttggtgc gataactaaa ccttgtaatt cgtgacgatc tggatcgatt
    17581 ttttctaaca ttggtaatcc aaatgcagct gttttccctg tacctgtctg tgcttgtcca
    17641 ataacgtctt ttccagctaa tgctagtgga atcgtttctg cttggatagg cgttgcttct
    17701 tcaaaaccag cgcgttcgac tgatttcaac aattctggtg ataattctag ttctttaaat
    17761 ttcaaatgaa tcctcctata tggttgttaa ctgaggatgt agcttttttg ctaccccgtc
    17821 gatttgttcg gtcaaagtgt attgtttctt tttgacagtg gccacgcacg tttttatcca
    17881 ttcttagccc ctgtggcacc accgaaaaat cactttgcga agtttaggca ttagaaaagc
    17941 caaacgggtc gcgttcagct ttatcattat tatgacatct ggcttcaaca agttgtttct
    18001 atggcaaaac cagtccaatt tctcttcatc tttcggcaat aggttattct aacatagttt
    18061 ttcgttttct gcaagtttac agatttttat ttcatttgct gaagttgttc taccacttca
    18121 aataagccca tgctgttgct gccttttagc ataatactat ctgttgcttc aagattttgt
    18181 ttgatagcat caatcaattt attcttttct ttttccaaat agaacacagg tagttggggg
    18241 tatttttggt tcaattcttc ttttagtgca tgcatttgtt ccccataaag gaaaatcatg
    18301 gcgaatttct caggatcgat atgttcactc atttgcgcat gcatatttaa agactctttc
    18361 cctaattcca gcatatctgc taacacagcg attctgcgtc cttttgttgg cagattttta
    18421 aaagtatcta ataccagtcc catggctgtt ggatttgcat tgtagacatc gctcaaaata
    18481 gctgcaccat ttcctgccgt tagccattcg gttctgtttt gagtgataga aacatgggcg
    18541 agcccttggc gtatctcagg tatggacagt ccaaagaagc gcccgatcgt atacgcaatc
    18601 aaagcattcg ttacattata acttccaggc agcgggatcg taaatgtttc tccttctact
    18661 acaaaatcgg tttgtgcttt tccttttgct gtcacttccg catgaacatc gccatttcca
    18721 ataccgaatg ttgtgactgt ttgtactaat gttgccgtta aaggtgtcag caacggttca
    18781 tctgcgggca caacgagtaa tccgtctgat acaagtccgt cagtgatttc cattttggct
    18841 ttagcgattc cttctcgcga cccaagattt tctatgtgtg cttcaccgat cattgtgatt
    18901 gctgcagctt ttggttgagc cataagtgaa agttccgtga tttcattggc gtgatccatg
    18961 cccatttcca aaacgatctt ttctgtatct tggggcatgt gcaaaatcgt gtaaggaaga
    19021 ccaatattat tgttgtaatt tccttgcgtc ttatatgttt tgtatttttc agacaagaca
    19081 gacgcggtta gatctttcgt ggtggtttta ccattgcttc ctgtaattgc aacgacttct
    19141 gcgcctactt tttccaagta ataggttgcc aattgctgca tggctttcaa aggatctgct
    19201 acaggaataa ctggaaaatt ttttggagct tgttcaacag gcaagctcca aaatgaagca
    19261 gatgctccgt ttgtgatcgc ttgctggata aattcatgtc catctcgcgt accagcaaga
    19321 ggaacgaata aacttccttc ggttatcttc cggctgtcaa attcgacatt ggtaatcttt
    19381 gtcagtgcag agcattcgct gcccacggct tgtgcaattt cttgtattgt tagattcatt
    19441 gagatctctc ctaaaaaagg ttgtgaaaaa agcgtttggc ctaaacggcg ggttcgcatg
    19501 actctcactt ccaagtaaat ttctctattc gtatttagaa gctagaatga acgcggttac
    19561 gcaatcactc cagcctcttc tttatttctc tttattcatt tttttcaaaa aaagattgac
    19621 gctgatggta tcgattcatt cctaactgga tcagttcttc aatcaaatca ccgtatttca
    19681 agcccatatt ttcccataag agtgggtaca tactgaactc cgtaaatcct ggcatagagt
    19741 ttaattcatt caggaataat tcatttttat ttgtcaaaaa gaaatcgcac cggctcaatc
    19801 cgcttccacc taacatcgtg taagctaact tcgcgtactc ttgcgctttt tgataaactt
    19861 cttctggcac ttcggctgga atctgcattt cgattttatt attgatatat tttgcttcat
    19921 aatcatagaa tgctacgtct tttacgactt caccaggcaa agtcgtccga acgtcttcat
    19981 ttcctaatac agcaacttcg atttcgcgcg cttcaattcc ttgttcaacg attgctcgag
    20041 aatcatactg ataggctgtt gctaaagcat tttgcagctc ttctcggttt tctgcttttg
    20101 taatgccgac actagaaccc atattcgccg gtttgacaaa catcggataa agcaaagaac
    20161 cttcacattg atcaaatact tttttaggat tttctttcca ttgattctta agtactggta
    20221 cataaggaac ttgcggcaca ccagcagctt gtaaaatata cttggtcatg attttatcca
    20281 tggcacatgc actggtcaat acgcctgcgc cgacataagg catattcaat gtctctaaga
    20341 agccttggat cgttccatct tccccgtttg gcccatgtaa aactggaaaa acgatggctc
    20401 cttcttcttt gatttcgccc ggattgatca cttttcctgt aaagccttcc tctgtctgtc
    20461 cacttgggtc ccatgaaaga tgcaagacat ctttgctggc aggtttttct gttagtaatg
    20521 gacctttgac ccattgtcct tcttttgtaa taaatacgag ttgaacttgg taataattat
    20581 aataaatggc atttaaaact gaaaatgcgg aaagaatgga cacttcatgc tctgcgctgc
    20641 gtccgccata tagtaaagta atcttcaaaa gattgtcctc ctgtattcta aatcgttcag
    20701 tgatttactc tcatatttta gcacaaaaca aaaataaacg aataacttat ttataaaaaa
    20761 acgagccagc ttctaaaaga acgagcgtca tttatttttt gtcagctaga ttatttgtcc
    20821 cgttttttat aaaaagttat gataaagaaa aggagggatg atgatggcgc aaacaaatcc
    20881 acgcagccgc ttggcagaaa tcattcgagt gttcatcaat tacaatgtag tgccaaactt
    20941 tgtacagcaa aaaaatcccg aacaggtaaa aaaagccttt gaagaactag gccccacctt
    21001 catcaagata ggacagatgc tttctgttcg agaagatttg ctttcttctg ccttcactca
    21061 aacattcaaa acattacaag atagtgtacc tagcgacaca ttttcaacgg tcaaaaagac
    21121 gatcgaaaca gaactttctc tttcattatc agatatattc gatgattttt caaaatcgcc
    21181 ttttgcctct gcttctatgg ggcaggctca tcgtgccaag ctgaagaacg gtgacgcggt
    21241 agtcgttaag atccaacacc ctaacatcgc cgaagagatc cgacttgatc ttcaactatt
    21301 tgaacgagcg atccctttga tcaaatacat tcctgaaact agcgtagttg atctaaaagg
    21361 ggtactccaa gaagtaaaac gttccttgat caatgaaatg gacttcttaa aagaaagtca
    21421 aaatggcgaa caattctatc aaaagaacaa tggctggaaa gagatccgca gccccaagat
    21481 ttatgacgct ttttgttcga aaaaagtgat cgtgatggaa gaaatgtctg gtaaaaactt
    21541 gaatcattta atgaacgccg aaaacaaaac tgaaactttt atcactggaa ttcaaaacaa
    21601 gcagctgaaa caagaagttg caaagctttt agttgagaac tttatgaaac aggtgtttga
    21661 tgatggtttt ttccatgctg atcctcatcc agggaatctg ctattccatg tactaacaaa
    21721 agaagaacag acacaagcta gccgaaaaac tgaaacagtc catgaaaaag agttcggttc
    21781 ctttgctttt cgagcctcca cttctgcaga agaccctgtt gcgccatata ccatcaacta
    21841 catcgatttt ggtatgatgg ggcatctttc tgcaggactt aggcaaaaac tcacacaagc
    21901 cgttttagcg ctgtatacga aagatgctta tcgaatcgaa aaagcggtcc ttcgactttg
    21961 tcagcaagaa ggctcgtttg atgaaagtcg gttccaccaa gaactgacaa gttttcttga
    22021 acagtattat gattctccta ttgatgaaat caacttgcaa gaagtattca cacatgtcgt
    22081 gacgatttgt catcaaaata atctgcagtt cgatcgtgat atcacgcttt tgctgaaagc
    22141 atttgggaca ttagaagggg tgatccgcgt cctcgatcct gaagtttccc tcatggaagt
    22201 cgcttcgcct tttgctcaac attattttct cactcatctg gatgtagaag atacattgaa
    22261 acaaagcgga ttagacttat tggaagggat gaaggctgcg cctaagatcc ctcaacagct
    22321 ccaccatcta ttagaaatgt ggacttcggg acaaggaaaa gtcaatttgg aattgaaaaa
    22381 gcaagacaaa ttattgagca ggatcgaaag tatgatcaat cggcttgttt tcggtatgat
    22441 tttagctgca ttgatcgtag ggtcctccct gcttgtccaa gcagcacctg tagaaaacgc
    22501 agaggtcgtt tccttattag ggatatttac gtatgctatt gccgcattcg tcattatttt
    22561 tttggcaatc gatgcattga tccaaatgta taagaagagg aaaaagtaga aaaaggttgt
    22621 gacagaaaga atcagcttca agaaataaga aggggtttta cataaattgt ttctcaaatt
    22681 tttgtgaaaa ttcggcttat ttttcgaaga ggctacttct gaaacaccga gaataaaaaa
    22741 tgtgaaaaag ctgttctgca cccagtaata agaacaatca aaaagggaac atggaacaca
    22801 tttatcctgt ttccctgttc cctttttgat gtattcgagc ataaataaaa taccttcgtt
    22861 acctactatc ttctgtactt ggtaaacctt agtcaattgc cttttttaac gcttgacgaa
    22921 aagacatatg atctttctcc gtaaagggtt ttggaccctt tgtccttatg ccagcttttc
    22981 ttaactttcc actatgataa cgttgttcta gaagcgtgcc gatattcgct tcgtcaaatt
    23041 cttttccaga gtgatggaac actcgcacac ccttcggcaa tacaagtgaa gctaaaccat
    23101 aatcttgcgt gatcaaaaag tcattcttct taaccatacc gacgatttta taatccgcac
    23161 tatcagctcc gcggtctacg tagacgattt ggacatgatt agcgtattct ttggtcgtat
    23221 aatggtccac actggtcacg ataaccacgt caagaccata ggattctcct aattttatga
    23281 catcttcttt tactggagaa ccatctccat caatgaatag cctcattctt tttcgccttc
    23341 ttccataaat gataaacagt tactaatccg ctcagtaaaa gaccaacatt gatccatttt
    23401 gccaagataa gcagttgtac actttctatc ggcactgatt catggttcag cgtgatcaat
    23461 aatagatgga ttggctctcc catttctttt gctaaaacaa acaaaagcgt catcaataaa
    23521 aactggtgga tcacactccc tttattttga gtagtatact tgacaacgat ccggcgatcc
    23581 attggaatag ctgtatcagt ttgataatat tccttattta gccagctgcc tgttactacg
    23641 tgccagaaac taagcagaaa gacacctatc gcaaaaccat ttggaatcaa gaggaccaat
    23701 aaagaagaac tcagtccaag caattgcata gccaatggag accatgttaa acgtttcaaa
    23761 atccatggtc cgactatttt tgctgcaatc aagcctgctg cataaggcaa atacataaaa
    23821 atcgaaagtt tttctaatcc gtacagtatg ccaacataaa aactgctaaa taaaaaaagg
    23881 aaattcccta gcattccatt tagaaaagta aacagattta gccagcttgg caacttccat
    23941 tccttcttct ggtgtcctaa aacaaacacg aacaagatga acagcagcaa gaaaccataa
    24001 atagcaagat caaaaagcct ttcatcgaat aacaatcggg catttctcaa aagaaacaat
    24061 aagccaaaga atatcaaaaa taaaacaagc tctcgcgtag ctaccagatt tcttttgatg
    24121 tctttgaaat ccagttcgta acgcggataa tgactaaccg tatggtaggc catgacgtaa
    24181 aaaagtgtat aaatagtaaa gcttgctgca atctgagtcg gtgcaggcaa ctcaatcgct
    24241 tgatacagga gaaatagcca gatagctgca aataagtact ttttcccatc catattgata
    24301 aaaccttgcg tcttttcgtg aaaattgacc gtggtattag caggtacaag ccatgctgca
    24361 ctcagcccta gcaaaacact tgaaaaataa aataaaggaa aataaaatac gcctaatatt
    24421 ccaagcaatg aaccagcacc accaatcagc agagcgatca tcagcaacgt gtaactatct
    24481 agaccaaatc gtagactgtt gactaaaaat agtccagtca tccgaaaggc ataaaacagc
    24541 gtaaatggca aaatcgtcag ccaattatgc gagtctgtta gtcccaaaaa taaaagataa
    24601 ggaataaaaa taaccgtgtt acttaagata aagggcgttg tttgtgtaaa attacgccca
    24661 aatcgtttga gtttttcgaa catgacaatg gctccttaaa cagtcttata actaatctgc
    24721 tcttcgattt tagcattaaa ggggaaataa accaatttta cagaatatat tcttgtaaaa
    24781 aaaaatacag aaagaagcat aagcttcttt ctgcattttt acggtacttg attactcaag
    24841 cagacaagcc cttctccaca aaagtcttgc ccgacacccc tgcatccggc aggtgataaa
    24901 gatagaaatc aattatcctg tgcctccaaa atcaattagg agctctgtaa accagagtcc
    24961 ttctcgaccc gtcgcataaa tttactttaa cacagttcct atgtttatgc gagagctttt
    25021 ttcattttat aatcgaccat ttgaaatcct tgaccgatat ctgaaataag ttcttctgta
    25081 atctcaaatc cttcatgctt ataaacctcg attgcttgat gattcccctg attcactcgc
    25141 aaaaagatct ctctttcctt tgtttgcgca gcaagttctt cataccagcg aaaaactgaa
    25201 gaagtcaatc cttgaccacg tactttattt agcaaatata atttacttaa ataaattttt
    25261 ccatttatct cttcataagc agtgtaaccg acagtctttt cttcgctttt taataaaaag
    25321 taggacacac cttctgtcag ttctttttga atctgttttt ttgactgata agttttcagc
    25381 atgtaatcca cttgtttttg accaatgatc ggcacaaaag cttccggcca tacttcttgt
    25441 atgactgcca tcagctcatc cagttcattt tctgttactt ttattttttc catacaccca
    25501 cgtccttttt tacattataa atgaccttgc gcttgatgga ataaaaagag catgatcatg
    25561 ctatacacac ccaccgacca tggtttcaag aaaatcacaa tctgcataaa ttccctaaaa
    25621 gataatttcg tcaaaccagc tactagacag atcaagtcgt ctggcgcaaa gggaagcagc
    25681 aaggtaacaa ctagtacttt tttaatatct ttcgtttttc ttgtcagcaa ttcatcaaat
    25741 ttctgatact tttttggcga taaaataagc tggacaaagg ctacgccata gtaacggaca
    25801 agcaaaaatc cgattgcttc cccaatcact aggccaatac aactatataa aagcccaaat
    25861 ccattgccaa acatcagcat gcccgctact gaggagatcc ctcccggcaa aataggaatg
    25921 atcacttgga tcacttgcaa cagaacaaat atcatcactg catacttgcc aaattgctgg
    25981 ataaacgctt gcaaagacgt gctcgatcga aaaatcccat gatgataagc ataaagaatc
    26041 aacacaaaga aaaaaaacag accaataatg ggcatgatct gaagacattt ttgtaaaact
    26101 gatccttttt tagacatcta tattccccac atcttttttc atttattaaa actgcctcct
//
LOCUS       DAFLWQ010000035        25896 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.036, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000035 DAFLWQ010000000
VERSION     DAFLWQ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25896
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.036"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(177..584)
                     /locus_tag="L1V16_001475"
     CDS             complement(177..584)
                     /locus_tag="L1V16_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBN1275821.1"
                     /translation="MKFLRKAGVKIGDVIIIGILIIPSFIPLFVFSIEKENETTEDAI
                     KYAIVQIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVR
                     TGWISKPGQTSICLPHKLVISIEKKESKDYYIY"
     gene            complement(579..1783)
                     /locus_tag="L1V16_001476"
                     /pseudo
     CDS             complement(579..1783)
                     /locus_tag="L1V16_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180763.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
     gene            1909..2127
                     /locus_tag="L1V16_001477"
     CDS             1909..2127
                     /locus_tag="L1V16_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1275822.1"
                     /translation="MSQYCHLTILKRERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTNHLPKRKKIMLIEEKNADVITF"
     gene            2148..2783
                     /locus_tag="L1V16_001478"
     CDS             2148..2783
                     /locus_tag="L1V16_001478"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1275823.1"
                     /translation="MVRHLFVDFQWSPEKISNRLKHEHMDFSISFITIYRAICNDLFD
                     TEPLSHGNKGLIRSLHHRGKTRHTKNHVESRGKICLTHSIHGHPKSADDRSDFGHWKA
                     DIVAGKTSGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEVLNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(2976..3215)
                     /locus_tag="L1V16_001479"
     CDS             complement(2976..3215)
                     /locus_tag="L1V16_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1275824.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYQFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(3239..4762)
                     /locus_tag="L1V16_001480"
     CDS             complement(3239..4762)
                     /locus_tag="L1V16_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBN1275825.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLIQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKLNKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEMHNWPTFYPASLSEHEIAQEMMAH"
     gene            complement(4780..4902)
                     /locus_tag="L1V16_001481"
     CDS             complement(4780..4902)
                     /locus_tag="L1V16_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBN1275826.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKQNKMKKLA"
     gene            complement(4932..5915)
                     /locus_tag="L1V16_001482"
     CDS             complement(4932..5915)
                     /locus_tag="L1V16_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBN1275827.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVIADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLEKFNHPLVFESDSSENH
                     YNGKHYHQHHQEHEFKSILLTSDQDIKKDFLFQLIDRLILTNQGSLYRFKGLIALQDQ
                     DFIVAIQGVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(5939..6088)
                     /gene="rpmG"
                     /locus_tag="L1V16_001483"
     CDS             complement(5939..6088)
                     /gene="rpmG"
                     /locus_tag="L1V16_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBN1275828.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(6109..6486)
                     /locus_tag="L1V16_001484"
     CDS             complement(6109..6486)
                     /locus_tag="L1V16_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275829.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(6518..6697)
                     /gene="rpmF"
                     /locus_tag="L1V16_001485"
     CDS             complement(6518..6697)
                     /gene="rpmF"
                     /locus_tag="L1V16_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBN1275830.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(6712..6981)
                     /gene="rpsN"
                     /locus_tag="L1V16_001486"
     CDS             complement(6712..6981)
                     /gene="rpsN"
                     /locus_tag="L1V16_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBN1275831.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(7504..9270)
                     /locus_tag="L1V16_001487"
     CDS             complement(7504..9270)
                     /locus_tag="L1V16_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1275832.1"
                     /translation="MQMIGGLTMKSFYKNKFALTNQGAEDLVKASISSFFVYCINMVP
                     AFIIMMLIDELVLENVKPPWLYFTVSFVTLLFMYWLLDREYENLYNSTYKESAHLRMQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKIVDQGTHSELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(9230..10984)
                     /locus_tag="L1V16_001488"
     CDS             complement(9230..10984)
                     /locus_tag="L1V16_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1275833.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLK
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(11094..11663)
                     /locus_tag="L1V16_001489"
     CDS             complement(11094..11663)
                     /locus_tag="L1V16_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HBN1275834.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(11681..13096)
                     /locus_tag="L1V16_001490"
     CDS             complement(11681..13096)
                     /locus_tag="L1V16_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBN1275835.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(13107..13775)
                     /locus_tag="L1V16_001491"
     CDS             complement(13107..13775)
                     /locus_tag="L1V16_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBN1275836.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(13906..14490)
                     /locus_tag="L1V16_001492"
     CDS             complement(13906..14490)
                     /locus_tag="L1V16_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1275837.1"
                     /translation="MESGLSHFEKVGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(14825..15055)
                     /locus_tag="L1V16_001493"
     CDS             complement(14825..15055)
                     /locus_tag="L1V16_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HBN1275838.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLTKLRYEDYLDIGFQLTDKGKKFIDDYKKRF"
     gene            complement(15070..16017)
                     /locus_tag="L1V16_001494"
     CDS             complement(15070..16017)
                     /locus_tag="L1V16_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBN1275839.1"
                     /translation="MRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVVT
                     NSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETGG
                     NAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKNI
                     EKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYFS
                     KAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDTN
                     IPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(16017..16859)
                     /locus_tag="L1V16_001495"
     CDS             complement(16017..16859)
                     /locus_tag="L1V16_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBN1275840.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            complement(16992..17717)
                     /locus_tag="L1V16_001496"
     CDS             complement(16992..17717)
                     /locus_tag="L1V16_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBN1275841.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGGTA"
     gene            complement(18178..18492)
                     /locus_tag="L1V16_001497"
     CDS             complement(18178..18492)
                     /locus_tag="L1V16_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBN1275842.1"
                     /translation="MHKDLLIICETGISASLLVSKMLETIRAKNLSYEIDYATIRNVE
                     EKLNYKDYDVLLLTPQVARSEEKVKEIIKKEKCTAQIVYIKQEDFRYMNIENIIASIE
                     ED"
     gene            complement(18508..20103)
                     /locus_tag="L1V16_001498"
     CDS             complement(18508..20103)
                     /locus_tag="L1V16_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HBN1275843.1"
                     /translation="MNLFSIISFLVIVICVWLFAYSRSRSVDTSGSEGFFMGGRSLTA
                     LPIAGTIIMTNLSTEQIVGQNGQSYHAGMEVMAWEVTATIAIVALAVIFLPKYFKYGI
                     NTISDFIEIRYDTVTKRIISILFIVTYMTSFLPVVLYSGSLVFNKIFHIDELLGVQPI
                     VAIIIVAMAIGIVGILYLLIGGLSLSANSDSIYGVGLLACGLLVPILGLMKLGDGSFV
                     GGIEHVVVNTPWLLNSVGSIDSAVVPWPTLFTGMLFNNLYFWCTNQMIVQKALSGKNL
                     AEAQKGAFLVGVFKILGALFLVFPGIVARNIFGDSLMSNPDNAYPFLVSEVLPKMIFG
                     IFAAVIFGAILSSFAGALNATSTLFSLDFYKPLINKKANDKQIARAGKTVTVVVGIIS
                     IIVAPFISFAPAGLYQFVQEFNGLYNMPLLVIILFAFYSKKATAFGAKTTIAVHIVLY
                     ALSKMLFQNIHFLYVLTALFVLDIIILMVVSKLKPDGEFVLNSFDTKVDIEPWKYTKV
                     TAIALVVIVILTYVAFSPIGFAG"
     gene            complement(20126..21016)
                     /gene="iolE"
                     /locus_tag="L1V16_001499"
     CDS             complement(20126..21016)
                     /gene="iolE"
                     /locus_tag="L1V16_001499"
                     /EC_number="4.2.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inosose-2 dehydratase"
                     /protein_id="HBN1275844.1"
                     /translation="MTKQIQLAIAPIAWTNDDMPELGSENTFEQCISEMALAGFTGTE
                     IGNKYPKDPEVLEQYLNIRGLKVASAWFSAFLTTKPFEETAEAFKAHRDFLHAMGAKV
                     IVVAEQGHSIQGIMTAPVFDDKPVFTDEEWKKLAEGLEKLGDLAHEKDMEIVYHHHMG
                     TGVQTTEEIDRLMEMTDPDKVKLLFDTGHLVFSGENPIAVYNRHQDRIKHIHFKDIRQ
                     ETAEEVEKEKDSFLNGVKKGVFTVPGDGMIDFTPIWTAIHASDYEGWIVVEAEQDPAK
                     ANPFEYAVKARSYIREVTGL"
     gene            complement(21033..22058)
                     /gene="iolG"
                     /locus_tag="L1V16_001500"
     CDS             complement(21033..22058)
                     /gene="iolG"
                     /locus_tag="L1V16_001500"
                     /EC_number="1.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol 2-dehydrogenase"
                     /protein_id="HBN1275845.1"
                     /translation="MNNIRVGIVGLGRLGKVHAQNLATGVSCCELTAACSLVETELAF
                     AQKKLGVKHTFSSYEEMVKSSVIDAVFIVSPSGFHCDQVRLAMENGKHVFTEKPLGLE
                     VEDIKKTQKVIEEHPEQVFMLGFMRRYDESYQYAKKMVEDGEIGEITLIRCYGIDPSE
                     GLESFVKFAMNNDSGGLFLDMAIHDIDLVRWFTGQEVDQVWAIGKNAAYPELDQAGEL
                     ETGAAMMSLSDKTIALLVAGRNAAHGYHVETEIMGTKGMLRVAQAPEKNLVTIMNDQG
                     IIRPCSQNFPERFREAFIREAQEFVSCIQEKRQPAVNAEDGLQSTKIALACQESFDTK
                     SLVQLKK"
     gene            complement(22082..23089)
                     /locus_tag="L1V16_001501"
     CDS             complement(22082..23089)
                     /locus_tag="L1V16_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1275846.1"
                     /translation="MRVKVGVIGTGAIGIEHIDRINQKTQGAYVTAVSDINVKAAKEV
                     AKRVDAKFFETGEALIASEDVDVVVVTSWDPTHEQYVLEAIKHGKYVFCEKPLAMDAA
                     GCRRIVDAEVAYGKKLVQVGFMRRYDRGYIELKEAIESKQYGEALMMHCAHRNPSADE
                     NYTTPMAISNTAIHEIDVLRWLLNEDYESVQMILPKKTSNSHADLHDPQLLIFQTKSG
                     VTIDLEIFVNCRFGYDIKCDVVFETAEVGMTDPAYTRIKSEEKNYTPVSPDWQTRFLD
                     AYDYEFKLWIDSIKNDAVVGPTAWDGYVAAITMMACHESRETKTKVMIQMDERPALYN
                     E"
     gene            complement(23202..24362)
                     /locus_tag="L1V16_001502"
     CDS             complement(23202..24362)
                     /locus_tag="L1V16_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBN1275847.1"
                     /translation="MNIQLKMPANLRIGGGTIQFLMEESEQLGNKPLIISDTVMEQTG
                     HLQKIKELLGKTDDQLAEYTDIQAEPTQENVYDALKLFQKHQCDHIIAFGGGSCLDTA
                     KVVAVLAANQLSLEAIHARNFDQLQAGIPLIAVSTTAGTGSEVTDVAVITNTKTAVKM
                     MMKDLVFMPQISIVDSDFTKTVPPKVTAATGVDALCHALESYVSVKANEVTQLFSLEA
                     MKKILNTLSQAYENSDDTEAREQMSLASTEAGIAFSNASVTLIHGMSRPVGALFHIPH
                     GISNAMLLPVFFEFSKDAIQTELATIARFIYPAAEDLSLEEAADYLIKKIQELCEQLS
                     IPTIRDYGIDQQAFMAALDKMAADALTSGSPQNNKKVPSHSQIKELYVQAYG"
     gene            complement(24438..25892)
                     /locus_tag="L1V16_001503"
     CDS             complement(24438..25892)
                     /locus_tag="L1V16_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010825391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-acylating methylmalonate-semialdehyde
                     dehydrogenase"
                     /protein_id="HBN1275848.1"
                     /translation="MTRFLRNYIDGRWVASRSTEFEEVMNPATEEALANVPLSSKAET
                     AEAVKAADAAFQTWKKVPVPVRGRYLFKLHQLLTDHKSELARLITLENGKSLSESLGE
                     VQRGIENVEHAAGITNLMMGDSLSTAATDIEITNYRYPIGVIGGITPFNFPMMVPFWI
                     FPMALAAGNTVVLKPSEKTPLLMEKIVELVEKAGFPSGVFNVVYGAHDVVNTLLQDPL
                     VKGISFVGSKNVGEYVYREGTKNLKRVQALTGAKNHVVVLKDANIDRAVKDLIGGAFG
                     SAGERCMAASVIVLEEEIADQFVEKFKAAAKAIKIGNGLDEGVFLGPVIRKDAQQRTF
                     DYIQKGVDEGAKLVLDGRENIPEKGYFVGPTIFDNVTMDMKIWQDEIFAPVASIVRVK
                     DLMAAVELTNESEFANGSCLYTNNASAIRYFRENVDAGMLGVNLGVPAPMAWFAFSGW
                     KHSFFGDLHANGKDSVEFYTHRKVVTARYAQSEI"
BASE COUNT         7944 a         5295 c         3975 g         8682 t
ORIGIN      
        1 ataagtaatc taaccgactg ttaactaaac cattgcaggt cccgttaaag atacttgtgc
       61 ctgttgtcac cgcttctttt tcttgtccac aagcgcttaa cacacttaat aaagcccctg
      121 ctattattaa taataatatc tttttcttat taaaaacctc ctcatctatt tccagattag
      181 taaatgtagt aatctttgct ttcttttttc tcaatactaa taactaactt atggggtaaa
      241 caaatactcg tttgaccggg ttttgagatc catccagttc taaccgcgat ttgatcagga
      301 ctattatctt ctttaactcg aattcttcca tctttaatct caacaatatt atattgtccc
      361 ttcgcaggat gataattcac gagtttatga ttgatcttat ccaaatcgaa gcgatccatt
      421 tccttgccat caatttgaac gatggcatat ttgatagcat cttcagttgt ttcattctcc
      481 ttttctatag agaatacaaa taagggaata aaagagggaa taatcaaaat gccaataatt
      541 atgacatcgc ctatcttgac accagctttt cttaaaaatt tcattaacga tatctggcta
      601 aacatattag aatttttcca tggaaatggt gaaatttttc ggaaattatc tgcattaaga
      661 gaatcagtta aacaaccctc aagttgttcc ttaatacatt gttgatccat cttcatacca
      721 ataaaaacta gtttattaat gcgttcacca aacaacggat gccaggcttc cttcaattcg
      781 ggtttttttg tataatcatt tgacactcaa ttttaggtaa actagctacc caataattta
      841 atgattcaat acttttatgg ctacccgatg tttcaaagat cgtcgaaaaa tcactatgtt
      901 gggcaaacca aagaaaccct tttgctcttg taatattgcc aggaaaattt ttatccgtaa
      961 gatgggcaaa tttttgtgcg tcaaggagta accgatttcg atagataaaa cttgagatac
     1021 catattcttc tgtttcagga atatgatttt gatagccaag ctctaactct ttgaaccagc
     1081 ccattgaata ggaagtctca tctatattaa aaagatttgt atttagaatt ttcgataagt
     1141 ctacttcacc tttaattgtc ctaattattt tggcattgga ctgtaactta gcaattagac
     1201 cgttaatttt gtaaatcgtc ttggttgaca ctaagtcact attatttaaa agtaatatgt
     1261 tacaacactc gaattgatca attaacaagc cacgaatatc ctgttcttct tcaactacat
     1321 taccttcagc ttttctttcc tgaatctttt cacccgtttc gaaattatcc caaaaacgtt
     1381 ttacatccac tactataata atggcaccaa tctctaatcg ttgggtcaaa tcaatgtcta
     1441 aagggttttt agctaatata attgcttgaa taattggaat tggtttgctg attcctgaag
     1501 cttcaataac aatttgattc aagtcagaaa attgcactaa ttgatctagt tcaacaatca
     1561 aatcttcgcg taatgtacaa caaatgcatc cattcggcat cgaaacaagt ttttctccag
     1621 ttcttttaaa acctttcttg tcgactaata ccccatcaac atttacttcc cctatgtcat
     1681 ttacaatgac agcaatttcc tttccgtgat caccgtacag aatatgattt agaagtatcg
     1741 tttttcctga accaagatag ccagttaaga ttgtaatagg tattttttca tagggaacct
     1801 ctttctatac cttgaattta cactttaagt gcaacacata aaaatgagtc ataatcgata
     1861 tccaactagt ataagtttgt cgagaacact cctagaagga aaataattat gagccagtat
     1921 tgtcatctta ctatactcaa acgagaaaga atctttctgc ttcacgaaga aggattttct
     1981 attagtataa ttggcaacga cattcagcat agcccgttta ctattttaca tgaactgaga
     2041 agaaacaaga aaaaaactaa tcaccttcca aagcggaaaa aaattatgct tatcgaagaa
     2101 aaaaatgcgg acgttatcac attctaaatg atccgtgagt ttggtcaatt gttcgtcatt
     2161 tatttgtcga ttttcagtgg tcgccagaga aaatctcgaa tcgtttgaag catgaacata
     2221 tggacttttc aattagtttt atcacgatct accgtgcaat ttgcaatgat cttttcgata
     2281 cagaacccct ctcacacggc aataaaggcc tgatccgttc attgcaccat cgaggaaaaa
     2341 caagacatac aaaaaatcat gtcgagtctc gtgggaagat ttgccttact cattcgatcc
     2401 atggccatcc aaaatccgca gatgatagaa gtgattttgg tcattggaaa gccgatattg
     2461 tagctggcaa aactagtggt acttgtttag tgactttgac agacagaaaa tcatgcttcc
     2521 ttttagcagg aaagaaggtc cccagaaaga aagccgctta tgtgagcgag aaaatgattg
     2581 aacttttaag cagtattcca aatgaggcgg tcaaaacgat cactccagat agaggaaaag
     2641 aattctccaa tcatttcgca gttacagaag tattgaataa tatgcccttt tattttccag
     2701 atcctcatgc ccttggcaac aatgaacaaa ttaaaatacg aatagactca ttcgagaata
     2761 cttgccaaaa tcgaaagaga tagctacggt agataactca acgataaatc agatgattga
     2821 aaaactgaat aacagaccta gaaagtgttt agattggaga acaccttatg aagtcttctt
     2881 tgataaagtg ttgcgcttga tttgacaatt caagaaataa taaaaagcag atcaaatcca
     2941 aataagggaa aaatgatcta ctctggtatt atcaattaat tggccaagct attatgccgt
     3001 tttgctaaac gtctacttct tccagtattg accttgataa aacaacaatc aggatcccgt
     3061 tttaatactc tatgaactgt gtcaatacta acatgtaaag ttgcagcaat atcagctaat
     3121 gtactcccat ttaatctcat ttgctttgca aattgataac gccgataagc atcaatattc
     3181 ttggaatcca tagacaataa tacttttctt accatgtatt tcctccaaag attggatttt
     3241 aatgggccat catttcttga gcaatctcat gctcagataa tgaagctgga tagaaagtag
     3301 gccaattatg catttcatta taaagttttt cttgactttc tccaccaaag aaaatatgga
     3361 aatgctctgc cttacttggt gcaattccat gatcgctaaa ttgaatatat ttaaaacgac
     3421 cagcacctgc atcatcagtt tcaaaattaa aacgaacacc acggtttcct ttttcataat
     3481 tcaaaatttt gtatccaaca tatttgtatg tgtattgatg atgttcaccg ttgactacaa
     3541 aatcaatggt gttgtcttta atgttgatag tatcaatatc tgtcttatag ccagtagtat
     3601 aataatcttt gtactcggca gctgtcatgt ctttattgag ttttgctttg taatcgaaaa
     3661 cttcatccaa aattccatct tttaacaacg gataaacaga ttgccattcg cctgtataat
     3721 cactcaattc gcgatccttc acatcggcat ctttaaagta cccattagca actgtctttt
     3781 catccttcgc ttctttttct ggaactacct cttcaccagc aaccatagtt gttttctcta
     3841 acgcttttag attgtcttcc attactgaaa cataatcttc accattatcc atttgttctt
     3901 ttgtaagact ttcaagagga ttcaatactt ccaattttat cccagcttca ttggccaaag
     3961 tttttgcgat tttatcatta gcattctttt caaagtaaat ataattgatc ttattttttt
     4021 taacatactc ttttaattca gctaatcgac cagaagatgg ctcttcttca ggacttagtc
     4081 cagcaatagg aacttgtatc aatccataat ccaaagctaa atatccaaag gctgcatgtt
     4141 gtgtcacaaa acttttttgt ttcgcttctt taagactagt ggtatagtca gcatccaacc
     4201 gtttcagttt agtcaaatac ttttcagcat ttgtctcaaa tacttttgct tttttcggat
     4261 acaatttaac taactgatcc ttgatatttg aaacttcctt aattgccatt ttgggtgaaa
     4321 cccacgtatg aggatctagt tcatgatggt gatcttcttc tccgtgatca tgatcttctt
     4381 cttcactacc tggcaataaa atcatgtctt ttgttccttc tactacatta ggcccagctt
     4441 tcttccaact ttctttagct tttggtaccc atgattccat gttttcgtta tgatatacaa
     4501 aaacatcagc atcatgagct tttgccatat ccttagctga gggctcatag tcatgaggtt
     4561 ctgatcccgc tggaaccatt aaatccacgt tcgcttcatc gccgacgatg tttttggtga
     4621 aatcatacat tggatagaat gttgttacaa tttctaattt tccatcttta tcattcgata
     4681 cttttgcatc attagtgctg gagcaagctc ccaataatcc tagagctgct atcccaataa
     4741 gtcctacact gattttcttc attctttttc cttccttaat tatgctaatt tcttcatttt
     4801 attttgttta tgttctttga taatttttaa tgcccttttt ctagttttga tattcgggct
     4861 tttaagtcgt cgatatgcac tagatatatc cgttttctcc attagaaatt acccctaatc
     4921 aatacttatc attatttgct ttccgccagt aatttatcaa aactctgttt gatcctttct
     4981 tcatccaaca tttttccaat tagaataata gtggtttggt ctttttgtcg agtggtgtat
     5041 tgaaaattaa cctgttcgtt taccccttgt atggcaacta taaaatcttg atcttgcaaa
     5101 gcaatcaatc ctttaaaacg atacaggctc ccttggttgg ttaaaatcag ccggtcaatt
     5161 aattggaata aaaaatcttt ttttatgtct tgatctgaag ttaagagaat tgatttaaac
     5221 tcatgttctt gatgatgttg atgatagtgt ttgccattat agtgattttc tgatgaatca
     5281 ctttcaaaaa ctaagggatg attgaatttt tccaaattat aaaaatcctt tttttgaatc
     5341 gtttcactat gtgtgaacat tcgaatatcg gataaagggt taatactttt gatttctctc
     5401 tgtaattttt ttagtgcaga taaattcaag ttttgttttc tagacacaaa aatgcgatct
     5461 gctatgacaa gttgcttaag ggcttgtggt tctctttcaa taagttcaaa actgtcacta
     5521 tcaataacag tcaataaact atcgatatat actcttcctc ttagttgagg cgctgttaaa
     5581 agtgtttgaa tgattggttg gggatctgct atacctgtag tttcaatgat gatttgtgaa
     5641 attggttgtt gatgttcttc tattgtttcc agtaaagaaa tcaatattgc taataaatca
     5701 ctgcgaagac tgcaacacat acatccatta tttagttgta acacccgttc ctcgctatga
     5761 actaataatt tgtgatcaat cccaacttca ccaaactcat tttcaattat aataatttct
     5821 tccctggggt agggtgagac ttgcaaggct tgattgatta gcgttgtttt tccagcccct
     5881 aaaaacccag aaacgattgt aactggtatg cccattttgt caccttttta ccacttagct
     5941 atttcacttc tttgaaaatt gcccgtctgc gcaattttgg cgaatacttt tttaattcta
     6001 accgttcagg gttattccgt ttatttttgc tggtgagata cagacgttct ccagtttcga
     6061 cacattccaa aataatattt tgacgcataa atcttcctcc ttcaatactt atcgatcttc
     6121 aagatatgct tgaatttgtt gtgcatcttc aaaagttaac tcgccagatt ccaattgtga
     6181 aactaaattt tctttcatat caacaggtat ctcccaataa ccatcaatac attgaaataa
     6241 ctcctcgtca tactcttcaa aaattggata gattcttaaa aaatcatcaa atgataagcc
     6301 ttggtcctca tagtaatctt tgactaatcc attttcaatt gcctgttggg tcggtaaacc
     6361 cgtttcagta ataattcctc tctctaccat cgaacgataa aaagtgcatt tatctagcga
     6421 ttgctgggtc gtttcaagat aatactttaa tccttcttca actaaaggtg ggtaaataat
     6481 ttccattttg attccctcct aaaagttata tattaaacta ttttgaagct cctttaatta
     6541 ctttctttcc attatagtac ccttttaaag atacatgatg gctacgtcta taatcaccat
     6601 tcgcttcgtc aaatgaaatt tctggtttta ctacagtttg atgagttctt cttaaccgtt
     6661 tcttcgcctt agatgttttt cttgctggta ctgccatgat atttcctcct tttaccaact
     6721 tgcttttttt actccaggaa tcaacccttg atgggcaagt tctctaaact taatacggga
     6781 cataccgaac tttcgcatat accctcttgg acgaccatcc gtctgatcac gaagcctcag
     6841 acgattcgga tttgaatctc ttggcaattt agcgagagcg gtgcgatctc ctgcggcttt
     6901 taattcctga cgtttatctg cgtacttttc aatcatcgcc atttgtttct ttgctttagc
     6961 aattttcgac ttttttgcca tataccttta tactcctttt attttgattt agacatctca
     7021 aatcgtaatc gttacgtttt gacactgata ctttaccaac aagagttgct cttgtcaaca
     7081 ataaataaca tgaaataaaa ctcatatgaa tagataacta tttgaaaacg aatttatcgg
     7141 tacatagaga taatcaaatc atttaaaaga atatgcagtt taagctctga aaaataagaa
     7201 ttcactttta ttagtccaat caaacacaaa taccgtttta agtagctttt cctctactta
     7261 aaacggcaat atgaaagaaa ctataacttt ttattcaatc ttttatgttt aactggttta
     7321 tcgccaattt tttaaaactt tgattattcc ttatattata agaatagaca ttaagtgaac
     7381 taattcaatc atactgattc tttcgtgtat tcaaaattag atgctgttta ataaaattat
     7441 tctttttgaa aaagaattat aactatatcc caaaaattgt aggttaattt aaagcctatt
     7501 tcatcatcgt gattgagctt ctttttcata gacgaatttc tcagatagtt tagttttctt
     7561 tatgagattt ttgtatattt ctgaccttcg atacaactca ctatgagtac cttgatcaac
     7621 tatttttcct tgatccatca ctacaatttt atttaccttt tcaatagact tcaagcgatg
     7681 cgatataatt agtactgtct tatcttgtat taaacgattt aaactttcct gaatacgttt
     7741 ttcattttcc gcatctaaac tggcagtaat ttcatctaaa attaaaattg gcgcattttt
     7801 caaaaaagcc cgtgctatgg ataggcgttg tcgctctcct ccagaaagtg aacttccgtt
     7861 ttctccgacc aatgtatgat aaccgtcagg tagtttttca ataaagtctt cgcagttagc
     7921 taaacgagct gcttttttca cttcctcatc tgacgcttga ctatttccaa tacgtatatt
     7981 ttccaaaata cttgtattaa acaaagttac ctcttgaaaa acaatagcga ttttgctaaa
     8041 caaagaagct ggagatacac gtttaatatc atacccatca attaaaatac agccttcatc
     8101 ataatcatac agtctagaca ctaatttcaa gatactagtt ttcccggaac cactagcacc
     8161 tactaacgca gtcacttctc cttgtttagc cgtaaaagag atatgatcta aaattggggt
     8221 attgttatca tatgagaaag agacatctcg caactcaatg tcaaaagatt tcagaggact
     8281 atctgatccc tcttggatac tggtttcctt catagctcta attcgctgta ttttaggagc
     8341 taaataaaat atttcaagca ctgcttcttt catagaatcg aaggaatcct ttatttttat
     8401 tgcggctagt aagtaaccaa cgacgtagag tatagtcact tcacccgtta acagtaagtg
     8461 aacacctact agaatgacta ctgctaaact aacatatgag aaaatagagg ataaggccat
     8521 gactgaaaaa gtacttaatt ctacctttaa atgaatcctt tcactctctt ccattttttt
     8581 gaaaagtctg tcttgaactt ttttagatag attaaagcta ttaatctctt gctgcaattc
     8641 tatagtttct tgaaattctt ccgagttttc tctcaaagta tcgtaatatt tagtattggc
     8701 tttcgtttgg gatttctttg ataacaagat taagacaaaa ctaaataacg ttggcaaaat
     8761 aacagctaat cccattttga cattaccaac caaaagcatc actgaaataa aagggaaaaa
     8821 cagagccata ccgccggctt taggtattgc atgactcatc gcatgctcaa taccttcaac
     8881 gtcagacatg atagtttgag ataaatctga taaattatgt tttgaaaaat aggataatgg
     8941 taaatttgac aaatcgtctg caatttgcat tcttaaatgc gcactttctt tataagtact
     9001 attatataag ttttcatact ccctatctaa caaccaatac atgaaaagca aagtaacgaa
     9061 cgatactgta aaataaagcc aaggcggctt tacattttct aaaactaatt cgtctatcag
     9121 catcattata atgaatgctg gtaccatatt aatgcagtat acaaaaaagc tagaaataga
     9181 tgctttaacc aaatcttctg cgccctgatt agttaaagcg aatttgtttt tataaaaact
     9241 tttcattgtc aagcctccaa tcatttgcat tctcataatt agtgaccaat tgtttataca
     9301 cttgatgttt agccattaat tcattatgat ttccacgttc tactattttc ccttctgaca
     9361 agacaagaat ttcatctaca gatttaatgc tggataatcg atgagctatc ataataactg
     9421 ttttttcttt catcagatgt tgaaaagcct tttgtagttc atactcatta tctggatcaa
     9481 tagatgcact ggcttcatcc ataataacaa tctttgcatc ttttaaaatt gctctggcaa
     9541 tagctatacg ttgtttttct cctcctgaca gataaactcc tttactacca attaaggtat
     9601 gctctctttc gggaaatttt tctaaaatcg attcgcaacc ggctaatctt agcgcgtcaa
     9661 atactttact tgctggcgct tgaggatttg ctatagaaac gttatcgtaa atactctgat
     9721 tgaatagttt cgtatcttga aagacaaaag caattgtgtt aataattgtg tcttttgaat
     9781 agtgatttaa aggcttacca ccaattttaa tctgtccctt atccacattg tagaaacctg
     9841 aaattagttt agctatcgta ctctttccgc ttcctgattt tcctactaat gcataaattc
     9901 ttttttgttc taaaactaag ttgaaatttt ctaaaacaca ctcttctttg tatgaaaagc
     9961 tgacattttc aaatgcaatg tcacaatttt taatctgtgt ctcgttccca tattttagtt
    10021 ggtcttgctt catttctaaa taaagggagt ctagtgtttc gactgcatat cttgcttcaa
    10081 acaagtgcat acttacatac attattctca tgaaagaaac aaaaataatt ccacttaaaa
    10141 aaaacaacat caacaagtca acagctaata tcttgggagt ggtaagagaa gttataaaaa
    10201 aggttatagg aactatcaaa atgcaaacta tgccaaaaaa tagccattga aaaagaacaa
    10261 aaggtgtttt cccactcaaa gaatacttat atgcaaactt agcataatcg ttaattgctt
    10321 tattcaaggc tttaaatgat gttactttag caccaaatat ctttataact tgaattcctc
    10381 ggatatattc taccgtttca gagcttaaca catctaacga ttcttgatat ttttgaataa
    10441 aatttgtatt ctctgtcatt ttctttaaca agaatacacc aattactaac atggcgatta
    10501 gaaccaatcc aattttaaaa ttaatgaaaa agcctaaggc aactgataaa acaggtgtta
    10561 ctatggcttg agcactatct ggaatcaagt gagcaattgc catatgtgtt ttagccgcgt
    10621 tgtcatcaat tgtctttcga atatatcccg aagaatttaa atcaaaaaaa cgaaaacttg
    10681 cttctgttaa accgctaatt cccttttttc tcaaattagt ctctaagcga aacccaagga
    10741 tatgagaaaa taagccagaa aaaatataaa ataaagctcc taaagttaac caagcaacag
    10801 tttgaaccgc ataactctta gctaaatatt catctcctac aataattaga gacttaagaa
    10861 atttgtaaat actgtaatat ccatagactg ttaatacgac agaaaaatca gaaaataaag
    10921 tggctaacca tccgtagtat ttcattttag ggacataact aaataatttt ttgtatactt
    10981 tcattttttc ctcccccgca ttcaatttct tctcttattc gtttacaact gttaatgctt
    11041 tccgtaatag cgtaaattag agatgtacaa acagatagaa ggtaaactac gttctatttt
    11101 ttgtattttt ttaagacttt tcttccaatc aatacaccaa tcatagataa acttgctaca
    11161 actaacactg aaatgattcc ccatatacct accgcatagt ggatcattgc atccattgtt
    11221 gcagcagatt gtcctttatc tatccaatct tgacgaaaac gatctgtaaa gaaccatata
    11281 ggaatccact gtccggcagc actgcctaat tgcattagag cccaagacgc aacttgagga
    11341 attgctcgat catatccaaa tacagataga ataatatcag ctaagatcgc catactaatc
    11401 gaactgataa accaaggtaa gtacgccccg cccattaacg taaaaaataa caataaaaca
    11461 attgtgtaaa tagtaaaaat tccttttcta gggtagttat agctaatata aacaaatatg
    11521 attccagata ataatccaaa aatccctggg gatatgctgt gaccaaacgc cccaccaata
    11581 ctactaacca ttattgaaaa aaagtaaatt actagggaaa taactgtagc taaaccaata
    11641 aaaatataat cttttgtttt catatatatt ctcctcaatt ctatttcgtt atgtcattaa
    11701 aaatctgttc tatcaaagtt gaatcttcta ctctaagttt tatatctttt tttattccac
    11761 cattttttaa ataaataatt ctattgcatg ttttataaag aaattccgga tcatgagtgg
    11821 ctataactac tgcacccttt tcttttaagt ctttaataag gtcagcaatc ctttccatat
    11881 taatataatc caacccactt gtaggttcat caaatagaaa taaattagtt tttgacaatg
    11941 aagctataga aaccaataat ctttgttttt ctccaccgga taaatcaaac ggtaattgat
    12001 ctttcatttt ataaagttcc atttttttta aaattttttc ttgctgatct ttactaacta
    12061 tttcattccc cagggctaac tcgctcctca ctgattctgt gaaaaattgg taatccattt
    12121 cttgcattac taaaaacggc gatgacaaat tttttttatt ttcgattatc tttcctttgg
    12181 tagggcgaat aatcttcatg agtattctta gtaaggttgt tttccccaca ccgtttttcc
    12241 ctaccaaacc aataacatct ccaactttga catcaaaatt tatgtctttt agaatatttt
    12301 cataagtaat ttcttcaact tttaatacat ctgcacttac cttttcgata tagggaactt
    12361 caatcgaact attaaaaatg tcaaatttcc ttaatgcgtt attgttttca gtttttaaca
    12421 actgaatagt tgtagttttt acagttctat ttttaacaaa tagaacttga tcaattaatt
    12481 ctttcaaata gtaaaaacga tgttcagcta taacaatagt aaatccttta ttttttaaat
    12541 cacaaagtaa gtcagcaagt ttcttagtcg ctttgaagtc caaatttgaa gacggttcat
    12601 ccaatataat taatttagag tttagcgata aactacatcc aatagaaatt ttctgccgtt
    12661 caccacttga tagcgaaaaa atgtttttat ctaatatatt tgaaagatct aataattcag
    12721 ctaattcatt gattctttta tccatatgct cttttgtaaa tccaaagttt tccatcgaaa
    12781 atactaactc actcgttgta tttgttgtaa agaattgtcc tctaggatct tgacttacgt
    12841 agccaatatt ttttgatata ctttcttgtg ttaaggattg tagcgagtta ttttcaaata
    12901 aaatttcccc aaccaatttt ccgtcataaa gtcttggaat aagtccattc attaacttta
    12961 atagtgtgga tttcccactc ccagaagaac cagtaatcaa tgtaagacta ccttttttta
    13021 ttgaaaaatt aaggtcaaca agcgcttgtt ccttaacatc cttatatgaa aaagaaacat
    13081 tgttaaattc aaacaattct ttcacctcaa atcaaaatac ttaagaaaaa aatagtaacg
    13141 gaaaacagga tgatatagtc taataagctc atgtttgttt tatagtaaga acttcttttc
    13201 acaggagatt ctatcccctt tgttattgca ttagcggtca tttcttcagc aatcatagtt
    13261 gcacgtataa gaacgggaac taacagaaat tccaaatatt gcagaggctg aaaaaaagac
    13321 aagcgaatgt ttctcatttt taaagattct ttaatcattc ttatttcaga acgataagtc
    13381 ggaaagaatc tgatcactac tgtaatactt aacattattt ttttcggtaa atgtattttt
    13441 tctaaagagg ataataattc attgctagta tagacactaa ccaacaacca tgagatcatt
    13501 acgaccggca acattcgaaa tacaatatat aaggatgtcc caaaaaatat agtaaaaaac
    13561 tctatcttga tagcatcaat aattttcatt actaaaaaca gaactgaata aatcaagatg
    13621 aaataaatac atgtctttat tttacgaaac atcaatacta aaactgtagc aataatgaaa
    13681 caccccactt gaaatatatt tccctttcct aaaaaaataa tgaccggaaa aaaaatattt
    13741 aaagtaatca aggttaacgg attgattttt gacactcttt cacctccaaa aaataagatc
    13801 gcactgttat cttaagctga taaaaatgca ccgttattca gataacagtg cgatcttatc
    13861 aaaaagcata actgagaaca attctcaatg caagcttttt tttaattaac tcagtaattc
    13921 aatccaccca ggaacagaaa attgatacaa tcttctggtt aatagcatag tcttttcttt
    13981 tgaatagcta tgcttcaata tatcatagaa tgtagcgtag aatgagtaaa tgtagaagtg
    14041 gatttcttct tcattaaaga ctaaattttg attgatcatt ccgatagtct ttaacttatc
    14101 tagacaacag actgtctttt ttgtcacaaa tgatgtaatt ttttcaacaa tatcttgata
    14161 tttggttcca gctgattgga ataaaaccaa atcgaatata cgtttattct caaaaatata
    14221 attaataaat ggatctaatt cattgaagtt ctctctccaa cttttctcta tatctatatt
    14281 ttctaagttt aagaggtatt tggtaaactc ttcattatac atattaataa gcgcattaat
    14341 atgcggctga ataatttctt caaataacgc ttccttagaa gtaaaatgtt tataaaaagc
    14401 acccgtagtt acgcctgcgg tcaagcacag ttgccttatc ttagtttgct gaaatcctac
    14461 tttttcaaaa tggcttagtc cactttctat taatttttgg tgagttgtaa tataatctct
    14521 ggtttctatg ggtacttcct cctaataaga tgaattaact atattatctt acacaggact
    14581 tgaagtttca atcgttaacg tctattactg aactcattcc ttagagctaa actaatgaga
    14641 aagagcaaaa taactgatac aaaaagcaat cctacaagaa ttaatagact catctaaatc
    14701 attcaccttt tctaaaataa tccgagaaag atttaaaaaa attatatcca gctattagga
    14761 taagtcctat cataatcact ccaatagcca ttttcttatc ctccctaaaa ataaagcctt
    14821 ttacttaaaa cctttttttg taatcgtcaa taaatttttt ccctttatca gttaattgaa
    14881 atcctatatc taaatagtcc tcatatctaa gtttagtcag catctcactt acagatgctg
    14941 gactaacact tagaactttt gctaaatcat tattttttaa tttctttttt ctttttgata
    15001 attcctgaat tgctagtaaa taaattagta tagtagttgt tttaatttgt accataccta
    15061 ccctccaaat tatttcgaaa ggccttcagc aattttatcc aggttccatt tcatcatcgc
    15121 atagtaacta tcaccatctt gtcctttttc tgcaattgaa tcagtaaaaa tcgttgaata
    15181 gataggaata ttggtatctt ttgatactgt tttcattggt ctatcgtcca cactgctttc
    15241 tacgaataag gagggaactt ttgttgtgcg taatttttca actaagtgtt ttatttgatc
    15301 tggtgttcct tcttcttcag tgttgatttc ccaaatgtaa gcagaaggca cattatacgc
    15361 tttcgagaaa tatttaaagc atccttcact tgtaacaatc atttttttat cattcggaat
    15421 tgaagcaaat ttagatttag cttctttgtc tagagaatcc aatttttcaa tatacttatc
    15481 tagattttct ttatagaatt ttttattatc aggatctttt tccgctaact gtttttcaat
    15541 atttttagcg taaataatac cgttttctaa atttaaccaa gcatggggat cttccttccc
    15601 tttctcactc tgaccctcta agtaaataac atctatgcca tcacttgctg caaaatagtc
    15661 tttgttttcc tctttgttcg cattttttac taattttgta aaccaagcat ttcctccagt
    15721 ttccaagtta acaccgttat aaaaaatcaa atctgctttt gaagtttttt gaacatcttc
    15781 aggcaaaggt tcatattcgt ggggatcttt cccaataggt acgatactgt gtaaatcaat
    15841 tttatctttt gctatatttt cagtaatatc tgctaaaatc gaattagtaa ctactacctt
    15901 taatttttcg ttcgaagcca ctgtatcttt gtctttacta tttgttgaac atgccccgaa
    15961 tataaaaaga gcaatcaaaa tccccagact tcccagtact gctttccatt ttctcatcat
    16021 aactttctct ccttctttct taaaaatttt tgttttggtg agattagaaa actaattaca
    16081 aataagaatg ccgctgttaa aacaatactt gatcctgctg ctatgttaaa actataacca
    16141 atgaacaaac ctagcaatga tgagcacgct ccgactgtcg ccgaaataaa tatcatagtt
    16201 tttaaactgt ttgcatataa atatgctgta gcagctggtg taattaacat tgcaacaatt
    16261 aatatagttc ccacactttg catagctgtt actgctacta aagttaatag aatcattaat
    16321 agataatgat aaaaactgac attcatcccc attgcttttg ccattaatgg atcaaaagaa
    16381 gtgattaata attctttaaa aaatagaaca actgtaacca acactaaaac agaaacgcca
    16441 attgtaatcc acttatcaat atcttgtaca gctaaaatat ttccaaataa gatatgaaat
    16501 aaatccgttg agctatttgc aactcctata aggataactc ctaatgctaa aaaagaactg
    16561 aaagtaatac caattgctgt atctcctttt attacactat tgctttttat aaaagtaata
    16621 atgatagaag ctaatagacc aaatacaatc gcaccaataa aaaaattaat acctaaaata
    16681 taagaaattg ctactcctgg caaaacagca tgagaaatag catcacccat aagagacatt
    16741 cctcttaaaa taataaaaca acctactgtt ccagaaacaa tccctataac tacagatgta
    16801 attagagcat tctgtaaaaa gtgaaagtca tacagaccat taataaaatt ttgaagcata
    16861 ttattcccct tgtatattag agttagggtt ttaaccttcc ggttttgatt ggataaccct
    16921 atgaaccatc gttattttaa tttggtatta actcatttct tttgagataa tatatttatt
    16981 ggattgagag gctaagccgt tcccccctct ccaataaata tagtatctcc ataggctttt
    17041 tttaaattct cttcattaaa tacagattct acacttccgt gagcaattag atttcgattc
    17101 aaaagaataa tattatcaaa atacttcttt accttgctta aatcatgatg cacaattagc
    17161 actgtttttc cctgatgttt caattctttt aacgtatcca taattattcg ttcactaact
    17221 aagtctatcc ctacaaatgg ttcatctaaa aatatgaaat ccgcattttg agcaagacat
    17281 cttgctaaaa gtacacgttg aaattgtcct ccagataatt ctcctatttg atgattagaa
    17341 tattttccca tatcgacctt ttccaaagcc tttgaaactc tttgccattc tgcattttta
    17401 attctttgaa aaactttcat tccggcatat gttcccatag atacacattc ttttactttt
    17461 attggaaaag taaaatcaat atcagctttt tgctctacat atgcaatctt caccagtttt
    17521 ttattgatat cttcattatt aatggagacc tctccctgat gagggataat atttaacatt
    17581 gctttaagca atgtagattt tccagcacca tttggaccaa taatacctgt taaagcacct
    17641 tcttgtattt ttaaagaaat ctcgttcaat gctaaaaaat cgttataaca aacattaagc
    17701 tttttcactt ctaacataac tttctccttc taaatgataa tgattatcac gatcatatgg
    17761 tatacaaaaa ttatatttta gtcaacccta aattttataa tttagatttt tttctgttgt
    17821 tgaagattag gatgtcaaaa ttatttgaaa ctactcgtat agtaaatagt aagtaatttt
    17881 caaaacacga agaaaaacaa aaagaaaaaa ggaaacgccg aagcatttcc tttcagtgat
    17941 ttaatgagaa caacacgatt tgacttagag tctcaaaaag tcgaataggt acactcattt
    18001 aagtgtctcc attcgacttt ttggggatga gctggctatt gaggtccgct taccctattg
    18061 aataaataca agattgggta tttctaataa gtccgccctt catattgggg tgatcggggc
    18121 gaacatgcca tcttttcata taccacctcc tcgacactca ataatcaaag attctcgtta
    18181 atcttcttcg atgcttgcaa tgatgttttc aatattcata taacgaaaat cttcttgttt
    18241 gatataaacg atctgagcgg tacatttttc ctttttgatg atttctttta ctttttcctc
    18301 agaacgtgcg acctgcggcg ttaaaagtaa aacgtcatag tctttataat tcagtttttc
    18361 ttcaacgttt cggatcgttg cataatctat ctcatacgat agatttttgg ctctgatcgt
    18421 ttcaagcatt tttgatacga gcagcgacgc actgattccg gtctcgcaaa taatcaatag
    18481 atccttatgc ataataccct cctgttttta gcctgcaaag ccaattggtg aaaatgccac
    18541 ataagttaaa ataacaatga ctaccaatgc tatagcagtc accttggtgt atttccaagg
    18601 ctcgatatcg acctttgtat cgaatgagtt caacacaaat tctccatcag gtttcaattt
    18661 ggaaaccacc atcaaaatga taatgtccag aacgaataat gccgtcaaaa cataaaggaa
    18721 atggatattt tggaaaagca tttttgatag tgcatacaag acgatatgca cggcaatcgt
    18781 cgtttttgcc ccaaaagcag ttgctttttt tgaataaaag gcaaagagaa tgatcacgag
    18841 cagcggcatg ttgtatagtc cattgaattc ttgaacgaac tgatacaatc cagccggtgc
    18901 aaaagaaatg aatggcgcta cgataatgga gataatcccc acaacgaccg ttactgtttt
    18961 accagcacga gcgatttgct tatcatttgc tttcttattg ataagcggtt tataaaaatc
    19021 cagtgaaaac aaggtcgatg tcgcgttcaa agctcccgca aatgatgata agatcgcgcc
    19081 aaagataaca gcggcgaaaa taccaaagat cattttaggc aatacttcac tgactaaaaa
    19141 aggatacgcg ttatctggat ttgacattaa actatcgcca aaaatattgc gagcgacgat
    19201 ccctggaaag acaaggaata acgcacctaa gattttgaag acgccgacta ggaaagcgcc
    19261 cttttgtgcc tcagctaaat tcttgccgga caatgctttt tggacgatca tttgattggt
    19321 acaccagaaa tacagattgt taaacagcat ccctgtaaat agtgtcggcc atggaacaac
    19381 agccgagtcg atcgatccca cagagttaag cagccatggc gtgtttacca caacgtgttc
    19441 gatcccgcca acaaagctgc cgtcaccaag cttcattaag cctaaaattg ggaccagcag
    19501 accacaagcc agcagaccga ctccataaat ggagtcacta ttggcactta acgacaagcc
    19561 gccgatcagc agatagagga tgccgacaat accaattgcc atcgctacaa ttatgatcgc
    19621 gacgatcggc tggacgccca gcagctcatc aatatggaag atcttattga acaccagcga
    19681 tccagaataa agaaccacgg gtaagaaaga agtcatatag gtcacaataa ataagatcga
    19741 aataattcgt ttggtaaccg tatcataacg aatctcgatg aaatctgaga ttgtattgat
    19801 gccgtattta aaatattttg gcaagaatat cacagccaaa gctacgatcg caatcgtagc
    19861 agttacttcc caggccatta cttccatccc tgcatgataa ctttgaccat tttgtccgac
    19921 tatttgttcg gtggacaggt tcgtcatgat gatcgtgccg gcgattggca aagcagttaa
    19981 gctccgccct cccatgaaga acccttctga tccagaagta tcgacacttc tggatctaga
    20041 ataggcaaat aaccatacac agatgacaat cactaggaaa ctgattatag aaaaaagatt
    20101 catcgtctag ctccttttca atagattaaa gaccggtgac ctctcgaatg tagcttctgg
    20161 ctttgactgc atattcaaat ggattggctt tagccgggtc ctgttctgct tcaactacga
    20221 tccagccttc atagtcgctg gcatggattg ctgtccagat tggagtgaaa tcaatcatcc
    20281 catcaccagg aaccgtgaag acgcctttct tcacgccgtt taagaagctg tctttttcct
    20341 tttctacttc ttcagccgtt tcttgacgaa tatctttgaa atggatgtgt ttgatacgat
    20401 cttgatgacg gttgtaaacc gcgattggat tttcaccaga aaagaccaaa tgtcccgtat
    20461 cgaacaataa tttaactttg tctggatcag tcatttccat taaacgatcg atttcttccg
    20521 tcgtttgaac gccggtaccc atgtgatgat ggtaaacgat ctccatatcc ttttcgtggg
    20581 ccaaatcccc taatttttct aatccttccg ccagtttttt ccactcttca tcagtgaaaa
    20641 ctggtttatc atcaaagact ggcgctgtca taatcccttg gatactatga ccctgctcag
    20701 ctactacgat gactttagcg cccatcgcat gtaagaaatc ccgatgtgct ttgaaggctt
    20761 cggcagtttc ttcaaaaggt ttagttgtca gaaacgcact gaaccatgca ctggcaacct
    20821 ttaagccgcg aatattcaaa tattgttcca acacctctgg atcttttgga tatttgttgc
    20881 caatctctgt tccggtgaac ccagcaaggg ccatttcact gatacattgt tcaaaggtat
    20941 tttcactacc aagctcgggc atatcatcat tggtccacgc gattggtgcg atggctaatt
    21001 gaatttgttt ggtcatattc tcacactcct gcttattttt ttagttgtac taaactcttc
    21061 gtatcgaatg attcttgaca agccaacgcg atcttagttg attgcaatcc atcttctgca
    21121 ttaaccgctg gttgacgttt ttcttgaata catgagacaa attcttgggc ttcacgaatg
    21181 aaggcttctc tgaatcgttc tgggaagttt tgtgaacatg gacggatgat cccttgatcg
    21241 ttcatgatcg tcacaagatt tttctcaggc gcttgcgcta cccgcagcat tcctttggtt
    21301 cccatgatct ctgtttcgac atgatagcca tgggctgcgt ttctgccggc aactagtaaa
    21361 gctattgttt tatcgctcag gctcatcatt gcggctccag tttcaagctc accagcctga
    21421 tccaattctg gatacgccgc atttttccca atcgcccaca cttgatcgac ttcttggccg
    21481 gtaaaccagc gaaccaaatc aatatcatgg atcgccatat ctaagaacaa gccgccgctg
    21541 tcgttattca tggcaaattt gacaaagctt tccaagcctt cgctcggatc gatcccataa
    21601 caacgaatca gtgtgatttc gccgatttcg ccatcttcta ccattttctt cgcatactga
    21661 tacgactcat catagcggcg catgaagcct aacatgaaga cctgttcagg atgctcttcg
    21721 atgacttttt gggtcttttt aatatcttca acttcaaggc ctaatggttt ttcagtaaag
    21781 acatgcttgc cattttccat cgccaagcgg acttggtcac agtgaaagcc tgatggtgaa
    21841 acaataaaga ctgcatcgat cacggaactt ttgaccattt cttcatagct ggaaaaagta
    21901 tgcttgacgc ctaatttctt ctgtgcgaat gctaattctg tttcaactaa actgcacgca
    21961 gccgtaagct cacaacaact gacacctgtt gctaaatttt gtgcatgtac ttttcctaat
    22021 cttcctaaac cgacgatgcc tactctaatg ttgttcatga aatacctccg ttttctgaga
    22081 attactcatt gtatagtgct ggtcgttcat ccatttgaat cattactttt gtttttgttt
    22141 cacgagactc atgacaagcc atcatggtga tcgctgctac atacccatcc caagcggtag
    22201 gaccgacaac cgcatcattt ttgatcgaat cgatccacag cttgaattca taatcatagg
    22261 catccaaaaa gcgggtctgc caatctggtg aaacaggtgt gtaatttttt tcttccgatt
    22321 taattcgtgt ataggctggg tccgtcattc ctacttctgc cgtttcgaaa accacatcac
    22381 atttaatatc gtagccaaag cggcaattca caaagatttc caaatcaatc gttacaccgg
    22441 attttgtttg aaagatcagc agctgcggat catgcaaatc ggcatgggag ttgctggttt
    22501 ttttcggcaa gatcatttga acagattcat aatcttcatt tagcaaccag cgaagcacat
    22561 caatctcatg aatcgcggtg ttgctgatcg ccatcggtgt tgtgtagttt tcatctgcgc
    22621 taggatttct atgggcacaa tgcatcatta atgcttctcc gtattgcttc gattcgattg
    22681 cttctttcag ttcaatgtag ccgcggtcat agcggcgcat gaagccaacc tgaaccaatt
    22741 tcttcccata agcaacttcc gcatcaacga tccggcggca gcctgctgca tccatcgcta
    22801 atggcttttc gcagaaaaca tatttcccat gcttgattgc ttctaacaca tactgctcat
    22861 gggtcgggtc ccaagaagtc acaacaacga catccacatc ttcagaagcg atcaatgctt
    22921 ctccggtttc aaagaattta gcatcgacac gtttggcaac ctctttagca gcttttacat
    22981 tgatatctga gactgctgtc acataagccc cttgtgtttt ctgattgatc ctgtcgatat
    23041 gctcgatgcc gattgcacct gttccgataa cgcctacttt tactctcaat tacttatccc
    23101 cctgttctgt tgtttaagca cacatagtat gcgcttacaa aattattcct gtgtagcttt
    23161 tattcttaaa aggtagagcc ctctctttgc tccgcctttt actacccata agcttgtacg
    23221 tataattcct taatttgact atgactaggc acctttttat tattttgcgg acttccgctg
    23281 gtcaacgcat ccgcggccat tttgtctaag gctgccataa acgcttgctg atcaatacca
    23341 taatctcgaa tcgttgggat cgacagctgc tcacagagct cttggatttt tttaatcaga
    23401 taatccgcag cctcttccag cgataaatct tcggctgccg gataaataaa tctggcgatc
    23461 gtcgctaact cagtctgaat agcatccttt gagaattcaa aaaagaccgg caataacatc
    23521 gcatttgata tcccatgagg aatgtgaaaa agtgccccca ccggtcgact cattccatga
    23581 atcaatgtga ctgacgcatt cgaaaaggca atccccgcct ccgttgaagc taagctcatt
    23641 tgttctctgg cttcagtgtc gtcgctattt tcatatgcct gagaaagcgt gttcaaaatt
    23701 ttcttcatcg cttccagtga aaatagttgc gttacttcat tggctttgac tgaaacataa
    23761 gattccaaag cgtgacatag cgcatcgact cccgttgccg cggttacttt tggtggtaca
    23821 gttttcgtaa aatcagagtc aacgattgag atctgtggca tgaaaacgag atccttcatc
    23881 atcattttga ctgctgtttt tgtattggta ataactgcca catcggttac ttccgaacca
    23941 gttccagcag ttgttgacac tgcaatcagc ggaatgcccg cttgcagctg atcaaaattt
    24001 cttgcatgaa tcgcttcgag acttaattga ttagcagcca aaacggctac caccttggct
    24061 gtatccagac agctgccgcc accaaaagca atgatatgat cacattgatg cttctgaaaa
    24121 agcttcagcg catcataaac attttcttgc gtcggttcgg cttgaatgtc tgtatactcc
    24181 gctaattgat catctgtttt tcccaacagc tccttgatct tttgaagatg cccggtctgt
    24241 tccataaccg tatcactaat gattaacggc ttgttgccta gttgttctga ttcttccata
    24301 agaaattgga ttgttccgcc gccaattctt aaattggcag gcattttcag ttgaatattc
    24361 acagaaaaaa cctctctctg gcttatagcc tataacagaa tcctcgaagc tctttaacag
    24421 agcttcgaag caaatcttta aatctcactt tgcgcataac gtgctgtaac aactttccga
    24481 tgggtataaa actcaacact gtctttgcca ttggcatgca aatcaccaaa gaaagagtgc
    24541 ttccagcctg aaaaggcaaa ccaagccatc ggtgcaggca ccccaagatt gacccccagc
    24601 atcccagcat caacattttc tctgaagtag cgaatcgctg atgcgttgtt ggtatacaga
    24661 cacgaaccat tcgcaaattc agattcattc gtcagctcaa cggctgccat caaatctttt
    24721 acccgcacga ttgatgcgac cggggcaaaa atctcatcct gccagatctt catatccatc
    24781 gtgacattat caaaaatcgt tggtccaaca aaatagcctt tttctggaat gttttcgcga
    24841 ccatctagta ccagtttcgc tccttcatcg accccttttt ggatatagtc aaaggtccgc
    24901 tgctgtgcat cttttcgaat cactggtcct aaaaagaccc cttcgtccaa gccattgccg
    24961 atcttgatcg cttttgccgc agccttaaat ttttcaacaa actgatccgc gatttcctct
    25021 tccaaaacaa tgacggaggc tgccatgcag cgttcaccag cagaaccaaa agctccgcca
    25081 ataaggtcct tgactgcccg atcaatattg gcatctttca gcacaacaac atgatttttc
    25141 gctccagtca acgcttgtac ccgttttaga ttttttgttc cttcacggta aacgtattca
    25201 ccgacatttt ttgatcctac aaagctgatg ccttttacca gtggatcttg cagcaatgtg
    25261 ttgacaacat cgtgggcacc atagacaaca ttaaaaacac cgctaggaaa gcctgctttt
    25321 tcaaccagct caacaatttt ctccatcaac aatggtgttt tttctgaagg cttcagcacc
    25381 accgtatttc ctgccgccag agccatcggg aagatccaga agggcaccat cattggaaaa
    25441 ttaaacggtg tgatccctcc gattactccg attgggtaac gataattcgt gatctcaata
    25501 tcagtcgccg ctgttgataa agaatctccc atcattaaat tggtgattcc cgctgcgtgc
    25561 tccacatttt cgattcctcg ttgaacttct cccagtgact cggacaatga tttcccattt
    25621 tccagcgtga tcaaacgcgc caattcactt ttatgatctg ttaaaagctg atgcagcttg
    25681 aacagataac gtccgcgaac aggaacagga acttttttcc aagtttgaaa cgcagcatcg
    25741 gcagctttaa ctgcttcggc tgtctctgct ttgctagaca acggtacatt cgccagcgct
    25801 tcttctgtag ccggattcat tacttcttca aactctgttg agcgactagc gacccaacga
    25861 ccatcaatat aatttcttaa aaatcttgtc atttat
//
LOCUS       DAFLWQ010000036        25789 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.037, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000036 DAFLWQ010000000
VERSION     DAFLWQ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25789
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.037"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            438..992
                     /locus_tag="L1V16_001504"
     CDS             438..992
                     /locus_tag="L1V16_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1275849.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(1165..1638)
                     /locus_tag="L1V16_001505"
     CDS             complement(1165..1638)
                     /locus_tag="L1V16_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1275850.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            1650..2186
                     /locus_tag="L1V16_001506"
     CDS             1650..2186
                     /locus_tag="L1V16_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1275851.1"
                     /translation="MPARIHHISIVNRFIRPTFDFYHNILGLKLLMKTINQDDHTMYH
                     LFFSDNHHRVGTELTFFEVQEGNNQFFGTNTIERTILKVPSEASLHFWEIYFETQGVC
                     HYGIESFSGRPILRFEGPDATRLALVPLREFEDIDDYFPYVTDQIPTEHAILGIDAIQ
                     LRVQYSDATERELLSVGW"
     gene            2226..2597
                     /locus_tag="L1V16_001507"
     CDS             2226..2597
                     /locus_tag="L1V16_001507"
                     /inference="COORDINATES: protein motif:HMM:NF013098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1275852.1"
                     /translation="MTILENQDTQFYQEVQIIQDRENPVAIEGIGSVHHVAFGVENKS
                     DLQRIDKQLQERNFINSGIKDREFFVSLYYRDPNQLLIEIATGEGNLDAKAYENQSPR
                     FEEIPLFLPQYLNFIREQVEQ"
     gene            2881..4152
                     /locus_tag="L1V16_001508"
     CDS             2881..4152
                     /locus_tag="L1V16_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBN1275853.1"
                     /translation="MKLSTQEKQLKNVSLKIPKNKISIFTSVSGSGKSSIVFDTITQE
                     AGRQLNDTYDSFTRLFLPKYSRPEVDEIDNLSTAIVVNQKKIGGSARSTLGTITNINA
                     LFRVLFSCFATPSLGYANAYSFNDPSGMCSVCQGIGKTIAFLIGLLYFSAIDNADFVF
                     SDPFTAEVLSGIEEQAKNHGYFVLVHNVNSAEDVKTIQRNWRFEGFIVVGVRVKEFLE
                     LNNVFDGPVVYIDTHLSKETLRELEQQMNRLFVNTNDYQASTLAVEHLIHYGHEKIAF
                     LSFDYIVGEPSVIQERHQAYIDTLKKYHLTFKSHWIYNNSEFERIYQELAEFTAIVVT
                     GDYLAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNPGNKGAIAFHQ
                     LIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            4397..5422
                     /locus_tag="L1V16_001509"
     CDS             4397..5422
                     /locus_tag="L1V16_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1275854.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            5716..6825
                     /locus_tag="L1V16_001510"
     CDS             5716..6825
                     /locus_tag="L1V16_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBN1275855.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASASTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            6908..7804
                     /locus_tag="L1V16_001511"
                     /pseudo
     CDS             6908..7804
                     /locus_tag="L1V16_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648409.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            7820..8644
                     /locus_tag="L1V16_001512"
     CDS             7820..8644
                     /locus_tag="L1V16_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1275856.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            8676..9986
                     /locus_tag="L1V16_001513"
     CDS             8676..9986
                     /locus_tag="L1V16_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HBN1275857.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            10134..11393
                     /locus_tag="L1V16_001514"
     CDS             10134..11393
                     /locus_tag="L1V16_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBN1275858.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            11403..12275
                     /locus_tag="L1V16_001515"
     CDS             11403..12275
                     /locus_tag="L1V16_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1275859.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            12287..13117
                     /locus_tag="L1V16_001516"
     CDS             12287..13117
                     /locus_tag="L1V16_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1275860.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            13157..15340
                     /locus_tag="L1V16_001517"
     CDS             13157..15340
                     /locus_tag="L1V16_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBN1275861.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            15401..16621
                     /locus_tag="L1V16_001518"
     CDS             15401..16621
                     /locus_tag="L1V16_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HBN1275862.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            16618..18078
                     /gene="gtfA"
                     /locus_tag="L1V16_001519"
     CDS             16618..18078
                     /gene="gtfA"
                     /locus_tag="L1V16_001519"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HBN1275863.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            18155..19261
                     /locus_tag="L1V16_001520"
                     /pseudo
     CDS             18155..19261
                     /locus_tag="L1V16_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            19583..19792
                     /locus_tag="L1V16_001521"
     CDS             19583..19792
                     /locus_tag="L1V16_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBN1275864.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            19785..19934
                     /locus_tag="L1V16_001522"
     CDS             19785..19934
                     /locus_tag="L1V16_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBN1275865.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            20088..20753
                     /locus_tag="L1V16_001523"
     CDS             20088..20753
                     /locus_tag="L1V16_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1275866.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(21037..22122)
                     /gene="xerS"
                     /locus_tag="L1V16_001524"
     CDS             complement(21037..22122)
                     /gene="xerS"
                     /locus_tag="L1V16_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HBN1275867.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            22456..22689
                     /locus_tag="L1V16_001525"
     CDS             22456..22689
                     /locus_tag="L1V16_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HBN1275868.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            22686..23093
                     /locus_tag="L1V16_001526"
     CDS             22686..23093
                     /locus_tag="L1V16_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBN1275869.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(24230..24748)
                     /locus_tag="L1V16_001527"
     CDS             complement(24230..24748)
                     /locus_tag="L1V16_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HBN1275870.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         8786 a         3931 c         4796 g         8276 t
ORIGIN      
        1 aattattgac gctcccgaca aaattatgat cttgcgtaaa gttataaaat attaataaaa
       61 atattttatt aatgaaaagc ttggtagcac ggttattcat atgctaattt atttcacttt
      121 atagtaaggg gagttcttag tatattgttc aaacttaaat ttcatataat ttaattatgt
      181 aaattagcta ttctaagaac ttctacggat aactgcccgt ctaaaattta aataagagct
      241 tagaatcttc atataagtaa ggttaatttt tttgtacaaa aaagtcggaa tattctgagt
      301 tactgaaatg atataaaatc ataaactaaa tcccttgatt ttattgactt tcaaaagttt
      361 atatatataa gttaatgatt atggtaaaat atatacataa tcattaactc agaatatttt
      421 taagaaggga aacaatagtg agctataatg tacaaccgtt aaggacaaat gaagagatac
      481 aagattttca gttttggcta agaagaacaa gtaatccgga aagagatagt tttttatttt
      541 tgtttggaat caataatggg ttacgtatgt cagatattat aggattaaaa gttggagata
      601 tacgaggcaa aagtaagcct attattgttg aacataaaac aggtaagcga aaaccgattt
      661 ttatagataa tttgagagaa gaaattttat tatatactga aggtaaagaa gaaaatgatt
      721 ggttatttcc gagtcggcaa caaggtcgac atataacaag ggatcgtgtc tatcagatat
      781 atgcagatat agcagaaaaa ttaggacgag atgatatagg aacacataca ttaagaaaaa
      841 cttttgggta tcactactac aagaaaacta gagacattgc taccttaatg tttattttta
      901 atcatagctc gcaagcaatt acaaaaaggt acattggtat aactgaagat gaaataggag
      961 catcacttcg tggatttaaa ctaggtgtat aatttaaaaa tttttataaa cagtaaagac
     1021 aaagattaaa agctattttt atctagaacg attttatttc ataaagttcg cggaataaaa
     1081 gctggggtta ctggtacttg gtataggttc gtgttatata aactaagtaa ttaaataaca
     1141 tttttaggtt ggaaaaggat gaaattaaaa aaagagaatc aatacggtct caaaaacgca
     1201 aacgctgcgg aataagaaaa atactgataa ctcaacgttt agcagactat ctaataggga
     1261 tagtctgctt ttttcgtttt tgaccatact tttgaccttc tgcaaacttc cttgcttttc
     1321 ctctgtagaa ctcatgaaat ctgcaaaacg aattgccgtt tcctctgtct gctttttcgc
     1381 gatatgggtg tatatatcat ccatagtggt tttaatatct gtatgtccaa gtcgaacata
     1441 cacttctttg acagacgcac cagattcaaa gagcagacta caatgggtat gacgaaaacc
     1501 atgaagtgtg atatgtttta agttattctc tttaatgatg attttcaaat tgtgatttac
     1561 atagtctaaa taaaggggct tattttcttc tgatgaaaac aaaagttgtt caccatcttt
     1621 tataggtttg attctcattt ttagatatta tgcccgcacg tattcatcac atttctattg
     1681 tgaatcgctt tattcgaccg acatttgact tttatcataa tatactcggt ttaaaattac
     1741 taatgaaaac aattaatcaa gacgatcata ccatgtatca cctgtttttt tcagataatc
     1801 accaccgtgt gggaactgaa ctgacttttt ttgaagtaca agaagggaac aaccagtttt
     1861 ttggaaccaa tacgattgaa cgaacgatac taaaagttcc ttccgaagca tcattgcatt
     1921 tttgggaaat atattttgaa acacaaggcg tttgccatta tggaatcgaa tcattttctg
     1981 gacgacctat cttacgtttt gaagggccag atgcaacacg attagcttta gttcccttac
     2041 gcgaatttga agatattgat gattatttcc cgtatgtcac agaccagatc cctacagagc
     2101 atgccatttt aggaattgat gccattcaac tacgcgtaca atattccgat gcgactgaac
     2161 gagagttatt gtcggtaggc tggtagcaca aagaatacgt cagtttcttt tcgggtcatc
     2221 aacgagtgac aatcttagaa aatcaagaca ctcagttcta tcaagaagtt cagattattc
     2281 aagatcgtga gaatccagtt gccattgaag ggattggtag cgtccatcat gttgcgtttg
     2341 gcgtagaaaa taaatctgat ttacaacgca tcgacaaaca attacaagag cgcaatttta
     2401 taaattcagg aataaaagat cgtgaatttt ttgtatcact ttattatcgt gacccaaatc
     2461 aattattgat tgaaattgct acaggggaag gaaacctaga tgcaaaagcg tatgaaaatc
     2521 aaagtccacg ctttgaagaa attcctttat ttttaccgca gtacttaaat ttcattcgtg
     2581 aacaagtgga gcaataatta gctaatcaaa tccatgacga agagtaagag gttgactcat
     2641 aagtcaaaaa ataaagaaaa acgcatcaaa tccattctaa agaatgttga tttgatgcgg
     2701 ttcctatttt tataaactat cattttcgac taataaaact acttatgagt cagcctctct
     2761 ttttttcttg atttttatac ctctttctag gtaaactaaa catctgccaa aaataccgtg
     2821 tctcattgaa acattctcaa ctatttcaaa ataaagggga gtaccaaatg aacgagtata
     2881 ttgaaattat ccacgcaaga gaaacaactt aaaaatgtca gtctcaaaat tcccaaaaat
     2941 aaaattagta tttttaccag cgtatctggt tcaggaaaat catcgattgt ttttgatact
     3001 attacccaag aagctggtcg tcaactgaat gacacctatg atagttttac ccgtttattt
     3061 ttacctaaat acagtcgtcc agaggttgat gagattgata atctttctac ggcgattgtg
     3121 gtcaatcaaa agaagattgg tggcagtgcg cgctcaacgt tagggacgat tactaacatc
     3181 aatgcgttat ttcgtgtgtt gttttcatgt tttgcaacac ctagtttagg atatgcaaat
     3241 gcttattcat ttaatgatcc tagtggaatg tgttctgtct gtcagggaat cggtaagacg
     3301 attgcatttt taataggatt gctttatttt tcggctattg ataatgctga ttttgtattt
     3361 tctgatccat ttaccgcaga agttttgtct ggaattgagg aacaggcaaa gaatcatggt
     3421 tattttgtat tggtgcataa tgttaattca gcagaagatg ttaaaactat tcagagaaat
     3481 tggcgttttg aggggttcat tgttgttggt gtacgtgtaa aagaattttt ggaattaaat
     3541 aacgtttttg atggtcctgt tgtttatatt gatacgcatc tttcaaaaga gacattaaga
     3601 gaacttgaac aacaaatgaa tcgtttattt gtaaatacaa atgattacca agctagtaca
     3661 ttggcagtgg aacatttgat tcattatggt catgagaaaa tagcgtttct ttcttttgac
     3721 tacattgtag gtgaaccaag tgttattcaa gaacgacatc aagcttatat cgatacatta
     3781 aagaaatatc atttaacctt taaatcgcat tggatatata acaactctga atttgagcga
     3841 atttatcaag aattagctga atttactgca attgttgtta ctggagatta tttagcggct
     3901 aaattagtaa aatttttaaa aaataagaat aaacgagtga tggaacaatt atcgattatt
     3961 ggatttgatg atattacttt tgcagaatta atggatcctg cgttgacaac aatacgacta
     4021 aatccaggta acaagggggc gattgctttt caccaactga ttggactggc caaacaagaa
     4081 gaaataaaaa atcaagtact actattagag ggagaattga tttctcgaga ctctgttcac
     4141 aaaatcaaat aaaaaagctc tgtgaaataa gtatagttaa caataaaata tccgaacgat
     4201 agagagaatg aactgtgatc tagcagttcc tcgtcgcaaa ttcactagaa ttagcattat
     4261 ttactctaaa ttgttcggat attttttctt gtttttaatt atgattacag tgcctatttt
     4321 taacgaaatt tgcttatttt caaaatgtat gattatatgt tagtaaacac tttcaaatat
     4381 gaaaagagga gctattatgg taggaattag ggatgttgca aaacgggcgg gtgtgtccat
     4441 tgcaacagta tcgcgcgtgc taaatgagga tccgacactt tcagtaaccg atgaaaccaa
     4501 acgaaagatt gcagaatcgg ttaattttta tcattatgtc aaaaaaagtc ccgttgcaaa
     4561 aaatttaaca aatattgcat taataacgac agtttctgaa gtagatgagt tggaagatcc
     4621 ctattttcga acgattcgca gagggattca agtcgaagca gaacaaagca aagtcaattt
     4681 gaagaaaatt attcgtttgt cagaaacacc gttggagcaa gacgatttgc taaaatgtca
     4741 aggtgtgttg attattgggc aggtgctatc ttctgtgatt gaagaagtat cagcaattaa
     4801 ttcgaatgtc gtagtgattg atgaccctag tattgaagct gaagtagatg cagtttatac
     4861 tgatttaaca aaagcaacga atcagcattt agatcgattg tataaaaaag gacaccgaaa
     4921 cattgcgttt atcggaggag gacgtgttcg tttagatagc caaggaaata aacacgtgtc
     4981 agatgatgat tatcgaaaaa tagcctatga gacgtggatg aaacaaaaag gattagaaaa
     5041 atatagtcaa atttatttag aaggctggac cacacttgac ggaatgcagg cagcagattt
     5101 acttttgaaa aaacatgcta aagataagtt gccgactgct atcatggtag gaaatgatcc
     5161 tattgctgtg ggggtttatc gttcacttca aaaaaatggt ctacatattc cagaagatat
     5221 ttcgattgtg agttttgata atattgaagt tgctgaattt ttaacacctg cattaaatac
     5281 ggtgaatgtg aatacagaag aaattggaaa actagcagtt cgcatggtta atgaacgaat
     5341 aaaagaagtt agaaatgttt cgatcaaagt gattgtttct aataatatta ttgttagaga
     5401 aagtgaaaaa aatatcgatt aaaaaagtaa acatccaaaa aagggtgttt acttttttgt
     5461 ttactaatat ttttagtaaa aaatctcgac aaaacattaa gtaaacagtt atggtgttgt
     5521 taacaaaaag aaaacgcatt caaaacagga ggaattaaga tgaaacattt caaaaaaata
     5581 gctttaacag ggatagctgt tttaactggg acattactcg cagcatgtgg tgggggagat
     5641 agtaattcta aagacgggca agtaacttta agctatgcga gttgagatac tgaccaagct
     5701 ccaggactaa gaaaaatgtt agatgaattt gaaaaacaaa atcctgatat caaagtagaa
     5761 atggagacaa cgccttggga tcaatattgg gttaaattag aagctgcaac aacgggaggt
     5821 aatatgccag atgtagtaac catgcactct agcgaatcct ataaatatat gtcacagaat
     5881 gctttgatgg gacttgatga tgttatcaaa gaaaatgata ttgacatggg aaactttact
     5941 gaaggaattg ctgatttcta tacgcttgaa gacgaactat acgcaatccc taaagatgct
     6001 tctgtagtgg ggctatggta caacaaagaa ttatttgata atgcaggtgt cgattatcca
     6061 gatgaaacat ggacatggga aacactcaga caagctgcaa ttgatttaac agatgaatca
     6121 aaaggcatct atggttttgc atcacatatt ggaacagaga ctggctactg gccatttatt
     6181 tatcaaaatg ggggagaagt atttgccgat gacaatacaa aatcaggttt gaatacccca
     6241 gaagcacaag aagctttagc tttttatcga gatattgcac ttgttgatca tgcttcacca
     6301 acaattacag aattacaaga tcctgataag ttaagtcgtt ttcaatcagg tagattagca
     6361 atgatgattg aaggaaactg gtttgcaccg ggatttttga aaaatgacta tctagttgaa
     6421 aatgttgctt ctgccgtgtt acctaaggga aaagttaatg caacaattac aaatggactt
     6481 ggttgggctg ccagtgcgag tacaaaatac ccagaagaag tgaaaaaact aatggcattt
     6541 ttagctagtg aggacgccaa taaaatccaa gcggaaacgg gggcatcaat cccagcacta
     6601 aaaggctttg aagacgagtg ggctgcttct tcagatacaa ttgatttgag tgcttttgga
     6661 aaaatgttgg agtatggagt ccctcgtcca tacaataaag atggattacg agctgaacaa
     6721 gcagaagttc aaattattaa ccgtattctg tctggtgaag taactgttga agatggaacc
     6781 gctcaaattg aaaaagaagt caatgcgata ttgagcggaa attaaattag ttaattatac
     6841 aatatacagg cgaaaggatt ctatttcgtc tgtatattaa tggatgaata ccaaaaaggg
     6901 ggatattatg aaaaatcgaa tttttggaaa atatcgtaaa gatcaagtga tatggggcta
     6961 tatttttatt tttccaacgg cattaggatt aattttatta aatatatggc cagcaattca
     7021 aacagcaatt ttaagttttc aaaaaacggt agggttcggt gatactgaat gggtcggatt
     7081 aagaaattac caaaaaatgt ttgcagacgg tgaagttttt cagtctttat taaacacatt
     7141 aatttatgca gtggtttcga tacctagtat tgttgtatta tccttgttgg tggcagtttt
     7201 aatgaataga aaagttaaag gattgtcgat ttatcggaca atttattttc taccagtcgt
     7261 tgctgcacca tccgcagtcg caatgatttg gcgctggatg ttcaataatg attatggact
     7321 gattaataac atgttggcta aaataggtct cgatggacca gcatggttaa cggatccatc
     7381 gattgcgatt tattctatta tcattgtagg agtttggagt gctattggtt ataacatggt
     7441 gttattacta gccggcttat aagaaattcc taaagattat tatgaagcag cggaaattga
     7501 tggtgctagt ccaatccagc agtttttcaa cattacgtta ccattagtta caccaacatt
     7561 attttttgta gttgtaacaa cagttatcaa tgctttccaa gtatttgatg ttatttttat
     7621 gatgattact cctaatagta ccgccatgtt taaatcacaa tcattagcct atttattcta
     7681 taaacattca tttattttaa atgacaaggg atatggttcg gcaatcgtta tgttcctttt
     7741 agtgattata ttaattatta ctgcaattca aatgaagttg cagaaaaagt gggtaaacta
     7801 ttaaggaggc tatcaaatta tgaaaaataa atttttttca aatgcgccaa tccatatcat
     7861 gcttatttta ggtggtattg caatggcatt accttttatt tggatgattt taacttcagg
     7921 gaaaacgttg gttgaatcta cccaaattcc acctacaatt ttccctgaga aatttcagct
     7981 aagtaactat caacaagtac ttgatttatt accattcatg gctttttata tcaatacatt
     8041 tttaatggtt gttggacgag tgattggctc ggttttattt tcagcaatgg ctgcatatgc
     8101 ttgtgcgcgt ctaagttttc cagggaaaaa tatccttttc agcttagtac ttattcaaat
     8161 gatgattccc ggttccattt ttattactcc acagtattta ttagcacaaa aattgggtat
     8221 tttaaataca attccagcat taatattacc aggggtagtt agtgcgtttg gtacgttttt
     8281 attaagacaa tttttcttag gtttacctga tgaattggag gaagcggcct atttagaagg
     8341 tgccaatatt tggacgatct ttttcaaaat tatgttgccg cttgctaaat caggattggt
     8401 tgcacttgga atattcacag cgttgtttgc atttaaagat ttaatgtggc cattgattgt
     8461 caatacttca attgataaga tgcctttagc tccgggatta gcaaacttac aaggacaata
     8521 tgccacgaac ttcccacaat taatggcagg ttcgttatta gcaatttggc caatagttgt
     8581 gatattcatc gttttccaaa gaaaattcat tgaaggaatt gctacaacag gtagtaaatt
     8641 ataaaactat taattagtga ttggagagta agtacatgac aaaaattaca tttattggtg
     8701 caggaagtac tatttttgca aaaaacgtat taggcgatgc gatgttaact ccaagtctac
     8761 aagatgcaca tattgcattg tacgatattg atgaaaaacg actaaaagaa tcaaatttaa
     8821 tgcttaaaaa tattaataaa aattcgaatg aaaatcgtgc tgatattgtt tcttattatg
     8881 atcgcaaaga agcgttaaga gaggctgatt ttgttatcaa tgctattcaa gtgggtggtt
     8941 ataaaccttc aacagtgatt gattttgata ttcctaaaaa atatgggttg cgacaaacta
     9001 ttggtgacac catggggatt ggtgggattt ttagaaccct acggacacta ccagtaatgt
     9061 tagactttgc taaagaaatg gaagaagttt gtccaaatgc ttggttattg aactatacaa
     9121 atccgatggc gatgttaacc atgggtgttt taaaagcgac gagtattaag actgttggtt
     9181 tatgtcatag cgttcaagta tgcgtaccag aattgtttga gcatttagga atagccgatc
     9241 aatatgactt aaatgacttt caatggaaaa ttgcaggcat taatcatatg gcattcttgt
     9301 tggaaattac aaaaaatggg gaagatttct atccaacaat tcgtcagtta gctgcagaaa
     9361 aaccaaatcc acatccagat tctgtacgtt ttgaattgtt gaaacgtttt ggttactata
     9421 ttacagaatc aagtgaacac aatgcagaat accatccata ctttattaaa tcaaaatacc
     9481 cagaattgat tgacgaatta gggattccgt tggatgaata cttacgtcgt tgtgaacaac
     9541 aaattaatga ttgggaaagc atgcgagagg acattgtaaa taatggggag ttaacacata
     9601 cgagaagccg tgaatatgct tcatatatca tggattctat tacgacagga actccgtcag
     9661 tgattgcagg aaatgtctta aataaaggct taatcacaaa cttaccgaca gatgtttgtg
     9721 tggaagtacc ttgtttagtc gataaaaatg gcgtgcaacc aacctatgtc ggtgaattgc
     9781 caacacaatt agctgcttta aatcggacga atatcaatgt tcaagaactg acagtagaag
     9841 ccgctttaac actagataaa tcaaaaattt atcaagcagc gtatttagat ccacatctat
     9901 catctgaatt gtctttaaca gatatcaaaa atttagtgga tgatttaatc gaagcacatg
     9961 gggactattt acctgaatat aattaaaaag aagctgaaag agtaaggaat tttcaattcc
    10021 ttactctttt cttagttaaa tttagtaaaa atattgacaa aacacttagt aaacagttac
    10081 attagtgtta acaaaaagaa aacgcattca aattgtataa ggaggagcat aaaatgaagt
    10141 ggtctaaaaa aattatttta gcttgtatag cactaggagc aacgatctct ttgactgctt
    10201 gtggaaaaaa tcaggaagat gcaagcggta aggtagaaat agagtttttt aatcaaaaaa
    10261 aagaaatgac tcaaacgatt caggagattg ctaaagattt tgaagcaaaa aaccctgata
    10321 ttcatgtaaa agttgtggat gtaccgaatg ctggtgaagt aattaaaaca cgtatgcttg
    10381 caggcgatgt accagatgtc attaatcttt atcctcaaag tatagaattg aaagaatggg
    10441 cgaaagctgg ttatttagag gacttaaccg aagaaccgta tttagagaat atcaaaaatg
    10501 gatatgcaca acgttttgct attgaggatc gtgtatatag cataccatta accgctaatg
    10561 tctatggttt ttactataac aaaactgctt ttgaggaaat ggggattcaa gcaccagaaa
    10621 cttgggcaga atttgaaaaa atagtagctg agattaaaga tcaaaacaaa gtaccgtttg
    10681 cgattgcagg agcagaaggc tggactttaa atggttatca ccaactagct atagcgactg
    10741 ctgctggtgg tgaagaggaa gcgaacaatg tttggcgttt ctcagaagtt aatggaatta
    10801 atgctgaaag caaagaaatg caaaaagatt ttaatcgatt agatttgtta agagaaccaa
    10861 aagctttgca aaacaactgg caaggtgccg gttataacga tacagtagtt acttttacaa
    10921 aaggtgatgc gttgattatg ccgaatggtt catgggcaat gccgatgatt cattcacaaa
    10981 atccagattt tgaagtagga acttttcctt ttccagcaga tgaagcaggt caaagtctaa
    11041 cgattggcgc aggagaccta gccttatcag tttctgcaac ttctcaacat aaagaagaag
    11101 ccaaacgttt tgtagaatat atgacaacac ctgaagcgat gcagaaatat tatgatgtag
    11161 atggtgcacc gtgtgctgtt gagggcgtta tcgagaatac tcaggattca ccattaagtg
    11221 gtttaactga acttgctttt actgatcgtc atttagtttg gttagccaaa gattggaata
    11281 gtgaaaatga tttttatacc ttaacaacaa attatttaca caatggcaat caaaaagcca
    11341 tgattaacgc attaaatgct ttctttaatc caatgaaagc tgacggaagg taggaaaata
    11401 aaatgaaaat aaaagaaatt ttaaatcgtt actgggcaat catttttgta gcaattccaa
    11461 ttattttgca gatgattttt ttctactttc caatggttca aggtgctttt tacagtttaa
    11521 ctaattggac tggtctgact tataattttg attttgtggg tttgaacaat tataagattc
    11581 ttttttctga tccgaagttt atcaaatcga ttggcttcac tttaattgtg acgctttgca
    11641 tgattgctgg acaaattggt tttggtattt tgattgcgcg ggcgttgaac gcaaatatta
    11701 aagggaaaac attctttaga gcatggttct tttttccagc ggtcttatcg ggcgtggttg
    11761 tttctttagt atttaaacaa atttttaact atggtttacc aaaaattggt agtatgttag
    11821 gcattgaatt tttacaaacc agtcttttag gaacaacatg gggagcgatt tttgcagtaa
    11881 tttttgtttt actttggcaa ggaattgcca tgccagtcat cattttctta gcgggttttc
    11941 aaagtattcc acaagaaatt attgaagctg ctagaatgga tggggcgaat gataagcaaa
    12001 ttttttggaa tattgaaatc acctacttat taccaagtat ttcaatggta tttattatgg
    12061 cattaaaagg tggcttaaca gcatttgatc aaatttttgc tttaactggt ggtggaccaa
    12121 gcgatgccac aacatctttg gggttacttg tttataatta tgcttttaaa aacaatcagt
    12181 ttggttatgc gaatgctatt gctttagtct tatttatctt aattgggatt gtttcactgg
    12241 cacaattaaa attatcgaaa aaatttgaaa tctaggaggt ttcccaatga aaacatcaaa
    12301 agaaaaaaat atttctaaat acttgctttt attattaggg ggcttcatga ttttagttcc
    12361 cttagtttca acgctattcg gttcatttaa aacaacaccc gatattatga ataatttctt
    12421 tcgttttcct aatccagcga ctttggaaaa tttccgaaga ttgttagcgg atggaattgg
    12481 tcattacttt tggaattcgg caatcatcac aatcattgca gtagttgctg tgacagcaat
    12541 tattcctatg gctgcttatt cactagcaag aaaaatgact cgtgggaaag catacggatt
    12601 gatgtattta tttttaattt taggaatttt tgttcctttc caagtaatta tgattccgat
    12661 taccgttatg atgagtaaaa ttggtttagc aaatatgtgg ggattaatct tactctatct
    12721 cacttatgcc gtaccacaga cactattttt atatgttggt tttattaaac taaatgtgcc
    12781 tatcagtctg gatgaggctg ctgaaattga tggggctagt cactttacaa cttatttcaa
    12841 aattgttttc ccaatgttaa aaccaatgca tgcgacgact attattctta atgctctatg
    12901 gttttggaat gatttcatgc taccattatt aattttaaat cgtgattcta atatgtggac
    12961 actaccattg tttcaatata attatacggg acaatatttt aacgactatg gtccaagttt
    13021 tgcttcctat acagtaggaa ttgtcacgat tacactagtt tatcttgctt tccaaagaag
    13081 tattatagct ggaatgagca atggagcagt gaaataacca ataaattatt ctcattataa
    13141 aggagttcat aaacttatga ttatatttga caatcacaca caaacatttc atttacaaaa
    13201 taaaaaaatt agctatctat taggaatcga agaaaataat tatttaacgc atctttattt
    13261 tggaaaaaag attacgcact attctggtgg gtatcgctac ccccgaacag atcgttcctt
    13321 ctcacccaac aatgcaaatg cgcaagatcg tttattatct ttagacacat taccattaga
    13381 atttccagga tatggacatg gtgattttag agaaccggcg cataatatta aattaggaaa
    13441 cggtagtcgt gtaaatgatt ttcgttatga tagctacgaa attcaaaaag gaaagcccag
    13501 cttagcggga ttgccagcct tatatacgga agatgatgat gaagctgaaa cgctgattat
    13561 tcaattgaaa gacgcgatta gtggattgac tttacagttg ttctacacaa tttatcaaaa
    13621 tcacagtgta attattcgtt ctacgcaatt agtaaataat agtgatgaaa cagtggagat
    13681 taaccgctta gctagtcaat caattgattt tccaaatcgt ccactcgagt taattcattt
    13741 aaatggtacc tgggcaagag aacgtcaaat gactagagaa aaaattcata cagggataaa
    13801 agtattagat agtaaacgcg gatcaagcag ccatcaacaa aatccgtttg ttgctttagt
    13861 agatgccaaa acagatgaat ttcaaggaga ggcatatgga tttaatttag tttatagcgg
    13921 taatcacgaa acggtgattc aaaaagatcc atttgaccaa acacgggtca ttatgggaat
    13981 taattcattt aattttggtt ggcaactaaa aactggcgac tcatttcaaa cgccagaagt
    14041 cgtgatggtt tatagtaatg aaggtctgaa tacgttatca cagacgtatc atgaattgta
    14101 taatcaccgt ttaattcgtg gaaactatcg tttaaaagaa cgtcccacgt taatcaacaa
    14161 ctgggaagca acgtattttg attttaacga agaaaaaatc atgaatattg tcgatgatgc
    14221 gaagaacttg ggcattgaaa tgtttgtttt agatgatggt tggtttggcg gtcgtgaaaa
    14281 tgacttcact tcattaggtg attgggttga aacagaaggc aaacttgctt gtggtttgga
    14341 aaatttagcc aagcaagtgc atgataacgg gatgaaattt gggatttggt ttgaaccgga
    14401 aatgatttct gaagatagtg aactatttcg agcacatcca gattgggcat tgggtattcc
    14461 aggtcgtgac cgctcaatta gtcgaaatca atatgttctt gatttttcaa gacaagatgt
    14521 tcgtgataat atctatcaac aaatgacggc gatttttgat cgtgtaccga ttgattatgt
    14581 gaagtgggat atgaatcgaa atatgacaga agtctattct gtcttgttgg actcaacgat
    14641 gcaaggtgaa gtggctcatc gttatatgtt agggttatat gaatttttag aaaagttaac
    14701 aacgaattat ccaactattt tatttgaaag ttgttcgggt ggaggcggtc gttttgatgc
    14761 aggtttcttg tattacatgc cacaaacttg gacgagcgac aataccgatg ccgtggctcg
    14821 tctgaaaatt caatatggaa ccagcttagt gtatccaatt tcaagtatgg gtgcgcatgt
    14881 ttcagcagtc ccaaatcatc aaacaggaag agaaacgagt ttaactattc gtggcaatgc
    14941 tgcgatggct ggtgtttttg gttatgagct agatctaacg caattaactt ctgaagaaaa
    15001 agcagaaatt aaagaacaag ttgcctttta taaaaagcat cgccaacttt tgcaatatgg
    15061 aactttttat cgcttggaaa gtccgtttga aggcaatgat actgcatgga tgtttgtctc
    15121 aaaagaccaa acagaagcca tggtctttta tttccgagta ttagcagaag ctgcgcatcc
    15181 attagtcaca ttgaaattag caggattagc agaagaagca acttatcaaa tggaagatgt
    15241 aacatttgct ggcgatgaat tgatgaatct cggtttttat attgactcag aactacatgg
    15301 tgattatgcg acacaacgct tttatttgaa acagatatag tagcttgaat ttacaatata
    15361 agtgcaacac caaaagagac tcattccaaa cgaagaaaat atgttttatt tacacgcatt
    15421 tactaaaaag cagcctgatt tgaattggga aaatgaagaa gtacgtgaag aaatctatgc
    15481 aatgattaac tattggttag ataaaggact aggcggattt agaatcgatg cgatattaaa
    15541 catcaaaaaa aaactagagt atggcatctt tgaatctgat ggagaagatg ggttagcctt
    15601 cattgggccc tggattctta atcagtcggg cattgaagtg tggttaaaag aaatgagaga
    15661 gcggacattt aaaccacata atagtatgac ggtagcagaa gccgatgttc ctaatgaacg
    15721 tttagatgaa tatattggtg aagatggcta ttattcgatg gtttttgatt ttagttatac
    15781 ggatattgat gtacctgaaa ctggtgaatg gtttaaagat agccaatgga catggacgga
    15841 tatgcgtacc aatattttta cgaatcaatt agttacgcaa gataaaggtt ggggcgcctt
    15901 atatttagaa aaccacgatc aaccacgttc aattaataaa tatattccag aagaatggat
    15961 caatgattat agtaaaaaaa tgttggcgac gctttttatg ttactaagag gtaccccttt
    16021 tatttatcaa ggacaagaac taggaatgac caacatagaa atggcatcat tagaagattt
    16081 tgatgatgta gctacgcatt ctcagtataa acgggcatta gaatatggat tggcaccaga
    16141 gcaagcattg aaagctgtca ataaacgaag tcgggataat tctcgcacac ctatgcaatg
    16201 gaatacgcaa aaaaatgcca gattctcaac ttctgataat gtatggttaa aagtaaatcc
    16261 taattatcca gaactcaatg cagaagctca gttaaccaat caacagtcgg tattcaatta
    16321 ttatcatcaa ttaattaaat taagaaaaaa tagtgtatac aaagacgtgc taatctacgg
    16381 acaatttcta ccagtgaaag ataaaaatga acatattttg ctttatgaac gccaattaga
    16441 agataaaatc gtattagtta tcttaaacgt tacagcaaca gaacaagaat attatgtaga
    16501 tgaacagtac caacaagtat taatcaataa ttatgaagat gttttattag atcaaagtcg
    16561 aaaattgcgt ttacgaccgt ttgaaagtat tgtattagct aattatggag gacaattatg
    16621 aaaattaaaa acgaagcaat gctcatcacc tatgcagata gtttaggaaa aaacatgggc
    16681 gaattaaaac aagtcttaga caaacattta caaggtgtta ttggtggtgt acatctgttg
    16741 cctttttttc catcgacagg tgatcgaggc tttgcgccga gtgattatac gacagttgat
    16801 ccagctcttg gaacatggga agatgtggaa gcattaggtg aagattatta tttgatgttt
    16861 gattttatga ttaatcacat ttctcgtgaa tcaaaatttt tccaagattt caaaaaaaac
    16921 catgagcagt caccatacaa agaaatgttt atccgtattc atgaattttt cccagaaaat
    16981 cgaccaacac aagaagatat tgatttaatc tacaagcgta aagacaaagc gccgtttcaa
    17041 acggtagaat ttgcggatgg tacgacagaa gaggtttgga atacctttgg ggaagaacaa
    17101 attgatttag atgtgaccaa agaagttgtg aaagaattta ttcgagaaac catcaaagat
    17161 atggcgaacc atggctgttc tttaattcga ttagatgcgt ttgcttatgc gattaaaaaa
    17221 ttagatacca atgatttctt cgtggaacca gatatttggg aacttttaga cgaagtgcgt
    17281 caagaagcag cgaaatatga cgtcgaatta ttaccagaaa tccatgagca ttattccatt
    17341 caaatgaaaa ttgccaatca tgattattat atctatgact tcgccttgcc aatggtcact
    17401 ctgtattcac tttatagtgg aaaatcagaa cgtttagcca attggttgaa aatgagtccg
    17461 atgaagcagt ttacaacatt ggatacgcat gatggaattg gtgttgtgga cgctcgtgat
    17521 ttattaacag atgaagaatt ggattacacc tctgaggaat tgtataaagt cggggcgaat
    17581 gtgaagaagg tctattcaag tgccaattac aataatttag atatttatca aattaacagc
    17641 acctattata gtgcattagg cgataatgac cgtagctatc tgttagcacg tgcgattcaa
    17701 gtatttgcgc cagggattcc acaaatttat tacgttgggt tattagcagg aaaaaatgat
    17761 attgaactgt tggaagcaac gaaagaaggg cgtaatatta atcgtcatta ctatgattta
    17821 gccgaaattg aagaagaagt gcaacggcca gtgattcaac aattatttgc acttttaaaa
    17881 tttagaaatg aatctgcggc gtttgatttg gatggaacga ttgaagtagc aacgccatca
    17941 gaatcagaaa tagtgattac acgtaaaaat aaaaacggta gtgatagtgc aacattaacg
    18001 gctaacttgg atacgaaaga atttatcatt gagtctaaag atataaaaat tttcactagt
    18061 gttgcattaa aattttaacc tattccatag aacaaaaaat cctttatact agcacttgga
    18121 tgacttatcc aagaccaata aaaaggactc atacatggat aagtataaaa caaatacagc
    18181 atttaataaa tggttttctg ccataaaatt aggaaaactt tctgtcaact cccaaaaatg
    18241 tatttttgat tacaattcgt atcgtaaaaa actgtctttt gaagctgtgc tcaagctctt
    18301 tctctacgca gttaatgaag aaaaagaaag tttgcgtgat ttgagtacag ctcttatcga
    18361 ccgatcgctc caactagaaa ccgatgtgtc atcgattagt catacccaat tgtctcgagc
    18421 atttaatgca cttgaaccta aagtgttaga agaaattttt caacaactgt tagaaaaagt
    18481 tcaacatcaa atcaaaccaa ccaagcgaaa tcatctgtat ctgattgatt ccagtacgtt
    18541 ttcgcttagt ttaaaacgtc ataagtgggc gactttccgt caaacaaaat caggtgtcaa
    18601 gttacactta aactattgtt atatggacga tactacgatg tatccaactg attttacctt
    18661 aacaaatgcc catgaacatg atctcaatca actaccagta ttggtgaatc aaccagaggc
    18721 aacttacgtg tttgatcgtg ggtattagga ctttgaaaag atggatcaga tgcattggga
    18781 tggctatttc ttcgtcactc ggattaaaaa aaacaccaaa gttcacgtga tagatactct
    18841 ggaaacatcg ccagaaacag aaattctacg agacgagctg gttcgtttag gatctaaaac
    18901 ctatctaacc gccaatttcc gactagtcac tgttcaagat aagaacggac gtgtgtttca
    18961 atttatcacc aatcgaatgg acgtctcttc aaaagaaatc tctgatatgt atcacgctcg
    19021 ttggcaaatc gaattgtttt tcaagcacat caaacaacac atgaccatta aaaccttctt
    19081 ttctcaaagt gaaaaaggcg tgcagaatca attgatttta acgatgattt ccgctctcct
    19141 cacgtttctc atcaaattgg agacgaaaac ggaaaaatca gtgttccaaa tcaaacgatt
    19201 ctttcgttat ttactgtttc agccctttga atgttgtcta gaaaaattaa ttcccacatg
    19261 agaaaaaaga aatttggctc gttacttttg gttttcagtt gaataacaga taaaaaattt
    19321 tctggaaaaa gtcatcctct gcgtcagcac agtttttttt gacttatttt cagaggaaat
    19381 agttttcaga atattctaaa atgttttatg caacactagt gatatttttt agaattagat
    19441 ttctaatgtg cattttttga gtattaagga gcaagtatac aaagatttat aaagctgatt
    19501 aaatttgaat aaaaatatgc aggaacgcta ctatttttag tagtgttctt ttttatattt
    19561 gaataaaaaa tgtggtggtt aaatggtggt tataacaaaa aatgaattaa tgaaattagg
    19621 ttatgggaag tatcagtctg agagaatcat acgacaggca aaagcaatta tggtttcaaa
    19681 aagctatacc tattacgaaa atagaagatt aggactagta cctgttgaat ctgtagaaga
    19741 agttttaggt atgaagatag aggtagagga ggattttcag aatcatggtt aattttaaaa
    19801 aagataaaaa tgggaaatat cattttactg ctagtttggg attcgacaaa cgaacaggga
    19861 aaagagtaca aaaaaacgta gaggggttaa aacagttaaa gaagaaaaaa agcgtatacc
    19921 gaacttgttt ctaattatgg aaaagaagca gaaacttctc aaagtactat gttgtttgag
    19981 gagttttttt ataaattatt cctaccttat tatcaaggga aagtagaaga aagaacatat
    20041 aaaaatcggt tatctacaat caaaaaaact tttcttattt ctttaaaatg gagttaagag
    20101 aaatacgtcc aattgacatt caaaagtggc aaaataattt attgagcaaa tataaaaatt
    20161 cttatgtaag aaacatgtat gggatttttc agatgtcatt agatcgagca gttgttttgg
    20221 gactacttga aaaaaatcct gcaaaagtta ttggaaatgt gaagaaaagg aaaactacag
    20281 ttgatttttg gacaaaagaa gaatttacaa aagttatttc aactttttat attgatgatt
    20341 tgtaccaaca ttttggtttt atttgtatgt ggttactttt tatgaccgtt atgcgtttgg
    20401 gagaagccac tgcattaact tggaaagata ttgattttga aaataaaaac ttgcgtgtga
    20461 ataaaacact ctattataag agagccaaaa cctatgagtt tgtagaaccc gaaacggctt
    20521 ctagtattcg tacaatcgaa ctagacgaca atacaattac ctttttaaaa gcttggaagg
    20581 agcgtcaagt ttcaatagga ggcatgtcgt ttgtactttc ttataatgga acacctactc
    20641 agaaatatac aatccgtcat attatgagaa gacatgcaac gatcgttggt gttcatataa
    20701 tccgcataca cggattaagg catagtcatg cttctttgct tatatcacaa taaaaagatg
    20761 cacttcgaat taaagaaagg ttaaaacatg ctgatgtaca aacgacttta ggaacttatg
    20821 gtcatttgta tctaaattca ttgagagaga taacaaatga tcccacagat tatatccaaa
    20881 ctaatttttc taaaatcaaa ccgacaccta tttacgataa taaaaaataa atgataaaca
    20941 aaagtaggat cacaccaaaa gaaacacact agaaaaacta taatacaggc ttttctagcg
    21001 tgttgtttct tatttccgcc tatttataca ttatactcat aaagcattta atgcatcgat
    21061 cgtagccgca ttgtctatat gggtatataa agttgttgta ttggtacttg aatgtcccaa
    21121 ttgttgggca gttaatacca atgaatttgt ctgttggtag agtctagtag ctaatgtatg
    21181 acgcagtttg tgagggctga cttgaattct aaagcctttt gaatattttg ctaccatccg
    21241 ttcgattgca ataccggata tacgcttggc ttctccttgg taaattgcta gaaataaagc
    21301 tttttcgttt tctgttactt tatatcgttc tttccgaata gctagataat tagctaaata
    21361 ttccattgcg aatgctgcta tattgacagc atctctttta tttccttttc tagttactac
    21421 cacattattc ttatctaaag ataggtcatc taaattaata tttataacct cggagagtct
    21481 caatccagat cctaaaatca gtgcattgat cgccaggtct ctttctacat ctcgttgata
    21541 atagatcaaa gctcgtttac tcaaagtatt tttatattca ttggcaatat aatctagata
    21601 attttgtgta tccttatcta gaaataattt tttctcaatg gcattggcac gtgcagctaa
    21661 cgtagtttta tctgtgatgg ttgctacttg atccatagga ttattgtcta agtatggttt
    21721 tcctagagga ttattggaac ttttcgaaag atatttaaat agaaccttta atgccgtgat
    21781 atttctattg atagtagaag tagatagacc taagttatta ttatctttga gcttagtttt
    21841 tgttgtctct ttttttacat tttcttttgt gcgacgtttc aaatgagatt tgtacaagtt
    21901 taggtcatag gcagttaact gtcttatcga ggtgatagaa gtatcaggaa cgatagactc
    21961 actcagaagc cattcataaa agagcttata attttttaga tattctaaag tggttcgagg
    22021 tgattgatct ttatcctcac gatcttgaac aaaatctttt atataatcgg gcatatgaag
    22081 tatgattgta tctatttttt gatatatttc tgtatttttc atgtcattca tcctttcaat
    22141 aagtagggga gaagagtatc tctataattg gactatacca attatagaat gttttgtcaa
    22201 ttggtatgct ctaaaattta ttaatttgtt tcaaaaaaag catataaaca ggtatacgtt
    22261 taataattta aaataaatgg tatacataaa tagggaagga aatagaaggg agcaatctaa
    22321 attttttgaa ttttcttaat taattatata gaaagaacaa tctttctata gagttagaca
    22381 tgagagggac tatgcttgat ttaaaatcaa caagcgtata tactgtatat acaaagaaaa
    22441 aggagggaga agactatggc aattaaagaa agaaaattta gggaagtggg gaactcagta
    22501 gtattaacta tttcaaagga gtttcttaaa gaaaatgggt taaatcccgg agatacggtt
    22561 tttttagatg aagaaaaact tcgagcggca attacaaaaa aacaagcctt atctgatgaa
    22621 attgatttag caatatctca agcattaact gaatatgata ctacttttag agagcttgtc
    22681 gataaatgag tattcattac ctagaagcca aagatattat aaaaatgaat gtaatccaaa
    22741 taaaaaaata ctctcctaat gaaccccttg gtgtaaagga tgcgaatgct ttagaaatgt
    22801 gtgtagggca acttcgagcc tcagcttttg gtgaagaggt ttatccttcg atttatgaaa
    22861 aagcagctat cctacttata caattgataa agaaacatcc ttttcacaat gcaaataaac
    22921 gtactgcttt cttagctact tttgtctttt tgaaaatcaa tggacagctt ttagctattg
    22981 atcaaaaaga tgctgtaaat ttagcggtat atattgctac gtatgataag gatttcgatc
    23041 aactaaaata tgaagtgatc aacactataa agacacatac gcagcccatt taaggagtta
    23101 ctgtatgtgt ctttataggg ttattagctg ctatagcgaa ataattgaag taaattacaa
    23161 atagctataa ttcaaatcca actatataga aaacgtaaat tttctatata gttggattaa
    23221 gataacgact atttatttta tcatattttt actataccct atacttttac ttggtatatt
    23281 tatgaataat cgcaaattta cccctatact actagtttgt aagttagatt aataaaaata
    23341 ctaaagttat ttgttctttt attaaataca cctacaactt ataaattgat ggtatttaga
    23401 taacacgaaa gaataaaaat aacagctgat agtaaagttt gttgacgatt gctactcaat
    23461 cgaaagtgag ttagtgcgta tgaacttgct tctgaaaact tatgaaatga aagacctttt
    23521 acatcttgca gaaatcggta ctgggattaa actaagcaat aaaaactaat gttcccctca
    23581 ttctttgaac ttctactatt tgatttattt attctgataa atgacgattt caccttcagg
    23641 atcttcaaat cccgtataga atttatttaa gatctcttca gtatcagtaa taggataggc
    23701 gataggccac ataccctttg atggttagaa taaactgctc aaaatctgta tcgtatgttg
    23761 gctttagcat attaacaaag gctatctcca aattataaac cataagcgtt gaatcgttct
    23821 taacaatttc aattcttcct aacccaaagt cagaagatat aattaccgga cttgccttac
    23881 ccttcatgtg ggttgttgag attccatatt taaagggaat tgtcggtact atcggcggtc
    23941 tgaaaaacat cccaaaaata aaaaaatctt tcccctgcta gtctcctaag tccctttgta
    24001 gcggatatgg caccataatc tcattttatc gaagtgagtc atggtttatc tgttggccaa
    24061 ccaaaattga tacaatctaa cgatgcaccc tctacggcat tctaggggag tgcacttgca
    24121 ttcacccaat aaaaaccggc agttagcaaa gaacttatgt agtcgtatgt tcttactgtt
    24181 aacatacaag aggtctcctt tccacaattg cttagcagta aacgggaatt tacaaagcta
    24241 atctcttcca ttttcttatc tttgttctaa aagtcccaaa tggagcaact gtatttacat
    24301 gaataaattt atatacttcc catacagccg ttttggttgc ctcgtctgcc cattttcttt
    24361 tgtgtgcagt gaatagatct tcatcactca ttgaatcaat catcatgtta atatcatcaa
    24421 tattacgatt gagaatttcc tctaattctt tcaatggtag atgtgcatag gtatttgtaa
    24481 accacttata taactctcct aactgattcc atttaaattg atcagaaggc gttttaacag
    24541 ataatccatt tctttcatca ttttcccatt ttagaattaa attcgtccaa ccaacttgat
    24601 atgctaaatt ttcagcaggt gttctatcca cttcctcaac tcttttatcc ttcaattctt
    24661 caggaatagt ttcaaattct aaaatatatt tagtataagt cctatttatt tcttttttta
    24721 attcttcttt atttttatat gttctcatta tattacctcc ataaattcct aattgtctcc
    24781 tttaattcat ctataatttc atccacgata ttttaatccg ttctacaatg catatctgat
    24841 atgcattgac tgtctaactc atatgtgaat gatttataaa atatcccaac gtctcatcta
    24901 aagaaatgtt gatcgtcagc aaggagctaa aaaatacgaa tatatttctt ttgtagtaaa
    24961 atcggactgg tttgcatatc attttcttcg taaatatcaa aatcatgtta actactatca
    25021 attactaata aaaactacca ctttaagcgt taagaactgt taagtttagt taagtgagga
    25081 tagttcacaa aatccattgt taaacttcac gaaagtggta aaactcaaaa tgctttatat
    25141 aggattacag catcgctctt tcttcgattg cgcgttgggt aaaaaatatt atgaagtaaa
    25201 aattgacgat gacacgttcc ttacggctca tcagatgaaa cagctacaaa aacgaaatga
    25261 tcaactcgaa gaaaatttaa ttctaaaaaa gcgattgcca tattcacgcc tcgctcgacg
    25321 aactattaaa ggtcaagatt tacctgaaga tcatcctttt taggaaattg aagcttttta
    25381 tgttgcacaa tgcatttata atactacaat gatgttttca ccagatattc ttctagggtg
    25441 cggtgtaatg aaacagatac acttgcaaaa gaaaattcac cgcgaattta ctaaaattat
    25501 gaataattat gttaatcttc cgaaattttt ttccaaaatt aagggatcaa gctggtgtta
    25561 tagattgttt aaggttggca aaaaaataac ttctttttaa acaattatag aaaaccgata
    25621 ctctgttaag ttggttgaca cggtgtcgat ttttatgact ttcttattct gaaacttcac
    25681 taacggacag tacctaaaaa gtctatagta tggacgttta cgagtactat tttatcaaaa
    25741 atgctgctca tttcaactta tatgttttag tgaactaccc ccacttagc
//
LOCUS       DAFLWQ010000037        25358 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.038, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000037 DAFLWQ010000000
VERSION     DAFLWQ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25358
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.038"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(132..509)
                     /locus_tag="L1V16_001528"
     CDS             complement(132..509)
                     /locus_tag="L1V16_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275871.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            765..1493
                     /locus_tag="L1V16_001529"
     CDS             765..1493
                     /locus_tag="L1V16_001529"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBN1275872.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1493..1747
                     /gene="purS"
                     /locus_tag="L1V16_001530"
     CDS             1493..1747
                     /gene="purS"
                     /locus_tag="L1V16_001530"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HBN1275873.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1749..2420
                     /gene="purQ"
                     /locus_tag="L1V16_001531"
     CDS             1749..2420
                     /gene="purQ"
                     /locus_tag="L1V16_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HBN1275874.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2421..4643
                     /gene="purL"
                     /locus_tag="L1V16_001532"
     CDS             2421..4643
                     /gene="purL"
                     /locus_tag="L1V16_001532"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HBN1275875.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4628..6067
                     /locus_tag="L1V16_001533"
     CDS             4628..6067
                     /locus_tag="L1V16_001533"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBN1275876.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6090..7142
                     /locus_tag="L1V16_001534"
     CDS             6090..7142
                     /locus_tag="L1V16_001534"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBN1275877.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            7139..7717
                     /gene="purN"
                     /locus_tag="L1V16_001535"
     CDS             7139..7717
                     /gene="purN"
                     /locus_tag="L1V16_001535"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBN1275878.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7714..9249
                     /gene="purH"
                     /locus_tag="L1V16_001536"
     CDS             7714..9249
                     /gene="purH"
                     /locus_tag="L1V16_001536"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBN1275879.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9265..10539
                     /gene="purD"
                     /locus_tag="L1V16_001537"
     CDS             9265..10539
                     /gene="purD"
                     /locus_tag="L1V16_001537"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBN1275880.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10661..11575
                     /locus_tag="L1V16_001538"
     CDS             10661..11575
                     /locus_tag="L1V16_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBN1275881.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11708..13273)
                     /locus_tag="L1V16_001539"
     CDS             complement(11708..13273)
                     /locus_tag="L1V16_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBN1275882.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13266..14717)
                     /locus_tag="L1V16_001540"
     CDS             complement(13266..14717)
                     /locus_tag="L1V16_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBN1275883.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14731..15747)
                     /locus_tag="L1V16_001541"
     CDS             complement(14731..15747)
                     /locus_tag="L1V16_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1275884.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15967..17055
                     /locus_tag="L1V16_001542"
     CDS             15967..17055
                     /locus_tag="L1V16_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HBN1275885.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17109..18635
                     /locus_tag="L1V16_001543"
     CDS             17109..18635
                     /locus_tag="L1V16_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBN1275886.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18637..19842
                     /locus_tag="L1V16_001544"
     CDS             18637..19842
                     /locus_tag="L1V16_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1275887.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20099..21076
                     /gene="guaC"
                     /locus_tag="L1V16_001545"
     CDS             20099..21076
                     /gene="guaC"
                     /locus_tag="L1V16_001545"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBN1275888.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21340..22764
                     /locus_tag="L1V16_001546"
     CDS             21340..22764
                     /locus_tag="L1V16_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBN1275889.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            23225..24334
                     /gene="pdhA"
                     /locus_tag="L1V16_001547"
     CDS             23225..24334
                     /gene="pdhA"
                     /locus_tag="L1V16_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HBN1275890.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24337..25314
                     /locus_tag="L1V16_001548"
     CDS             24337..25314
                     /locus_tag="L1V16_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBN1275891.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
BASE COUNT         8202 a         4317 c         5695 g         7144 t
ORIGIN      
        1 caaaaaagaa gcagatccgt tagcggttct gcttctttta gtttattata ttttcttatc
       61 aataatagga acctgatttt aaaagcggct acctctttac cgtgcctctt tacatacaaa
      121 aaatagagga attaagcgta aatggcttgg ctattataac taaaatgctg gttatggaga
      181 tgttgcagca agttttcgag aaaagcgtat tccatctctt gtccattgaa taagatctgg
      241 atacgataat gatttttgaa acgcttctgt tcatgaatct gactgattga aagttcgcct
      301 ttgtgttctg tctgataaag aaaagtcctt ttacggcatt cagcacagcg cttggttgct
      361 cggcggattt ttcggaatgt ataaaaacta gtatctttat tgcataaata aacgtctttg
      421 atcgacagca aatcattata tagacaggaa cgttcttcag ctgttaattc tgataaaaaa
      481 agctgacctt gttttattgc atcttccatc ggcaagtgcc tcctcgaacc cattatccaa
      541 atttttagtt aattctaata taccatcatt aagtataaat gtaaacgctt gttgatggta
      601 taagattttc gtttctgata aaacacgaac attaaaagaa tctaatgcct taaatgtaca
      661 tatttttgtt gatttataaa aagatgattg ctaaaattta aagtgaaaaa acgaacaaaa
      721 aacgatgtat ttgcttttaa tgtaaataaa aaggagagac gtacatggag aagaaagaac
      781 ttttgtatga aggaaaagcc aaaaaaatat atcttacttc tgatgagaac ttgatttgga
      841 tagaatattt agatcaagca actgcgttga atggcgcgag gaaagaccag ataagtggaa
      901 aaggagaatt gaataatcaa atcacaagtg caattttccg ttatctgact caaagaggaa
      961 taaaaaatca ttttattgaa caattgtcta aaaccgaaca attagcaaaa aaagtacaaa
     1021 ttatccctct ggaagtggtt atccgaaata ttgcagcagg aagtttctca aaacgtctag
     1081 gtgttcccga aggtaaagaa ttcatcaaac caatcattga attctactat aaggatgacc
     1141 agttggatga tccatttatc aatgaagagc atatctattt cttacaactt gcaaagccgg
     1201 aagaaatcag tgagctgaaa gcccaagcgt tggctattaa tgaaattttg accgaattat
     1261 ttgctaaggt cggtttggtt ttagtagatt tcaagctaga atttggccgg tcgaatggac
     1321 aaattttgct tgcggatgaa gtaacaccgg atacttgccg attatgggat gaacgtacga
     1381 atgaacatat ggacaaagac gtttaccgca gagatctagg tgatttgatc ccagtctatc
     1441 aagaagtata taaccgtcta tcggaactaa ctgaagaaaa ggagcgagta tgatgtattt
     1501 cgtaaaagta tatgtaacct ataaagattc agtgttagat cctcaagggg aggcagtaaa
     1561 aaaagcagtc catcgtatgg gatatgaaac aatcgaagat atccgaatag gaaaatactt
     1621 tgagatacaa cttgctgatg cagaagaacc aatcgataca gtgattgaaa cgatttgtga
     1681 caagctgctt gcaaatgtaa atatggaaac ataccgatat gaaatcaaaa aaatggagga
     1741 agtataacat gaaatttgcg gtcatcgttt ttccaggttc aaattgtgac gcagatatgt
     1801 tatgggcagt tcgcgagatc atgggcgctg atgccgaatt tgtacggcat gatgagtcct
     1861 ctttagaagg atttgatggg gttttactgc cgggaggatt ctcctatggt gactatttga
     1921 gatgcggtgc gattgctcgg ttttctacaa tcatggaaga agtgattcgt tttgctgaag
     1981 aagggaaacc agtattcggt acatgcaatg gattccagat attgacagaa gcaggacttt
     2041 tgccaggtgt actgagacga aatgagtctt tgcattttat ttgcaaaact gtaccattga
     2101 aagtcaaccc caagacggcc tttacttcag agtatgaagc cgacgaaata atctatcttc
     2161 cagttgctca tggggaagga aattatttct gtgacgaaga aacacttcaa gaactaaaaa
     2221 aaaataatca gattgccttt acttataatg acaacatcaa cggcagcgtg gaaaacattg
     2281 cagggattac gaacaaagca gggaatgtgt taggaatgat gcctcatcca gaacgtgcag
     2341 tagaagactt gctaggatca gaagatggga aacggttctt tgcttccatt ttaaaaaact
     2401 tcggaaaggt gaccgtatag atgaaaacat tgaaagaacc gacagctgaa gagatcaaga
     2461 aaaaaagaat ctatgccgaa tggggattga ctgatgaaga atatcgaatg atcgaagaag
     2521 atatcttagg aagaatgcct aattatacgg aaactggact gttttctgtt atgtggagcg
     2581 aacattgttc ctataaaaat tctaaaccgg ttctacgcaa atttcctact agtggacctc
     2641 atgtgttgca aggccctgga gaaggcgcag gcatcgtcga catcggtgat ggactagcag
     2701 ttgtcttcaa agcagaaagt cacaatcatc cttcagccgt ggagccttat gaaggagctg
     2761 cgacaggagt tggcggaatc atcagagata ttttcagcat gggggctcgt ccaattgcgt
     2821 tgctagattc attgaggttc ggcgaattag ataatccaag aacgaaatat ttactagaag
     2881 aagtagttgc aggtatcggc ggatacggca attgtatcgg cataccgact gtaggcggcg
     2941 aaattgcatt tgatccttgt tatgaaggaa acccattagt caatgcaatg tgcgtaggtt
     3001 tgattgaaca caaacatatc cagaaagggc aagccgctgg cgtcggtaat tcgatcatgt
     3061 atgtaggtgc aaaaacaggt cgcgacggta tccacggagc aacttttgcc tcagaagaat
     3121 ttaatcaaga agaagaacag caacgttctg ctgtacaagt aggcgatcct tttatggaaa
     3181 agctgctgct tgaagcgtgt ttggaattaa tcttgcatca ttcggattct ctaataggta
     3241 tacaggatat gggagcagca ggacttgttt catctagtgc ggaaatggct tcaaaagctg
     3301 gctcaggact tatattgaca ttagatgaag tcccacaaag agaaactggg atgacacctt
     3361 atgaaatgat gttatcggaa tcacaagaac ggatgttgat ttgtgttaaa tcaggagagg
     3421 aagaaaaaat ccaagaacta tttcagaagt atgatctaga tgcagtcact atcggtaaag
     3481 taacagacga cgggcaatat cggctatatc atcaaggaga agaagtagca aatctgccag
     3541 tcgatgcatt agctgaagat gcaccagttt atcataaaga aatgaaagaa ccagctcgaa
     3601 tcgtagaatt tcagcagtta gctccttatc agccagttat cgaagaacct ggacaagtat
     3661 tgcttgatct gctgcagcaa ccgacgattg cttcaaaacg ttcaatctac gaaacttatg
     3721 attcacaagt acaaaccaat acagttgtcc gtccaggaag cgatgctgct gtgatgaggg
     3781 ttagagggac gaataaagcg ttagctatga ccacagactg caacgcgcgc tatctgtatt
     3841 tggatccaaa aatcggagga caaatagcag tggcagaagc tgctagaaat attattgcta
     3901 gcggtggtaa gcccttggcg atcaccgact gcctgaacta tggttctcct gataaaccag
     3961 aagttttttg ggaattatcg acttcagctg acggaattgc tgctgcgtgt gaaacgttag
     4021 gaactcctgt tatttcagga aatgtctctt tatataatga aacggatggt caagcaatct
     4081 atccaacacc aatgattggt atggtcggat tgattgagga tcataaacat atcactactc
     4141 aggaattcaa aaaatcaggg gatctaatct atatattagg taagacgttt gcagattttg
     4201 atggcagtga attacaaaag atgcagcttg gaagaatcga aggtgtgatc cgaaactttg
     4261 atctatccat tgaaaagaga aaccaagagt tagtattgac agccatccaa aacggattga
     4321 ttgaaagtgc tcatgactgt tcagaaggtg gcttggcaat tgcactggca gaatcagctt
     4381 tcaaacatca gctagggata tctgtacagt ttgaattgtc ctctgctcaa ttatttgcag
     4441 aaactcaatc aagatttgtg ttgacagtcg caccggaaaa taagacacga ttcgaagaaa
     4501 tgatgggaga tgctgctgtt ttagcaggta aggtgacgga tgaagcgata atcgaaattt
     4561 cagcaactga cggtcagatc aaaatagaaa ctgcagtagc aagaaagtgc tgggaggatg
     4621 caatcgtatg tcttatgaag tgaagagttt aaatgaagaa tgcgggatct tcggtgtttg
     4681 gggtcatcca gacgccgcta gtgtggcata cttcgggctc catagtcttc agcatcgagg
     4741 acaagaaggt gcaggtatcg tgtccaatga tcgaggaaag cttaaggggc atcgagattt
     4801 ggggctgctt tctgaggtat tcaaagatca aagaaaattg cagcagttaa caggagaagc
     4861 tgcaatcgga catgtacgtt atgcaacagc aggcaatgga agtgtggaca atattcagcc
     4921 ttttctattc aaatttcatg atcagtcgat cggcttagcg cataatggta acttgatcaa
     4981 tgctcgttcc cttagaaaag agttagagga aaatggggcg atcttccatt ctaactccga
     5041 tacggagata ttgatgcatt tgatccgacg aagtgaagaa acagattttt taaataaatt
     5101 aaaaagtgct ttgaatgaag tcaaaggtgg ctttgcctat ttattaatga cagaaacggc
     5161 aatgattgcc gctttggacc caaatggttt tcgtccatta gcaatcggac aaatgaaaaa
     5221 cggagcatac gtgattgcct cggaaacttg tgcattagaa gttattgggg cacgttttat
     5281 aagagatgtc cagcctggtg agatagtgat catcaatgac gaaggaatcc agattgattg
     5341 ctttacgaag gacacgcagc tttctatttg ttcgatggaa tatatctatt ttgccagacc
     5401 agattcaaac atcgcaggga tcaatgtgca tactgcacgg aaaaatatgg gacggaattt
     5461 agcgaaagaa tcgccagtaa aagcagatat ggtcgttggc gtacctaatt cttctttgtc
     5521 agccgcaagc ggttatgcgg aagctagtgg aatcccttat gaaatcggat tagtaaaaaa
     5581 tcaatacatt gcccgaacat ttatccagcc aacgcctgag ctaagagagc aaggtgttcg
     5641 aatgaaatta tctgctgtac gaggagtagt ggaaggtaaa aaggtgatta tggtcgatga
     5701 ttcaattgtt cggggtacga caagcagacg gatcgtccat cttttgaaag aagcaggggc
     5761 aaaagaagtc catgtgagga ttgcttctcc tcctttgaaa tatccatgtt tttacgggat
     5821 tgatattcaa acgcgtaaag aactcattgc ggcaaatcac acgattgatg aaatcaaaga
     5881 atgtatcggt gcagattctt taggtttttt aagtgaagag ggtctgatcg aatcgatcgg
     5941 tctggaaaaa gatgctccgt attcaggatt gtgtatggct tatttcaacg gagattatcc
     6001 gacgccgtta tatgactatg aagaaaaata tcaggaatca ctaaaagaaa aagtatcgtt
     6061 cttttaaaag cagaccaaga agggagtata tgaattcaat ggcaaatgca tacgcaaaag
     6121 ctggcgtaga tgtcgaagct ggatatgaag tagtagaacg gatcaagaag catgtcaaaa
     6181 aaacggaacg tttaggtatg atgggcgcta taggaggatt cggcggttgt tttgatttat
     6241 cggtctttca attaaaagag ccagtccttg tctcggggac cgatggcgtg gggacgaaat
     6301 tagcagtggc aatcgaagca gacaaacacg atacaatcgg gatcgactgc gtagcgatgt
     6361 gtgtcaatga tatcttagca caaggcgcag agccgttata tttcttagac tacttagcaa
     6421 cggggaaaaa tgatccgtta cgtttggaaa atgtagtaaa aggtgtagca gatggatgtg
     6481 ttcaaggaaa tatggcgctg attggcggag aaacagctga aatgcctggt atgtactcag
     6541 gtaatgatta tgatctagcc ggatttgctg tagggatagc tgaaaaatct caattattga
     6601 caggagaaac gatcaaccca ggagatgtgt tgcttggaat agcatctagc gggattcatt
     6661 caaatgggta ctctcttgtt cgcaaaattt tctttgagca gcagcagttt tctttatcat
     6721 caaaactgcc agaattgaaa aaaacacttg gcgaagaatt gcttgagcca acgaaaatct
     6781 atgtttcttc cttgcttccg ctgatcaaag aaaagaaaat aaaaggagct gcacatatca
     6841 ctggtggagg gtttgtagaa aatatcccgc gaatgttacc agaatctatg gctgcacaaa
     6901 tcaaacttgg ctcatggccg attcttccaa tattcggctg tttacaaaaa tatggtgaaa
     6961 ttcctgagat ggagatgtat gaaatcttca atatgggcat cggtatggtc ctggcagtcc
     7021 aagaatcgaa agtaaaagaa atagtacacg aaattgagca agctggcgaa aaagtttatg
     7081 aaatcgggaa agtgatcgcc aaagaaaaac atcgtgtggt gtttatagga gaagaacgat
     7141 gagaatcgct gtttttgctt ctggaaacgg aagcaacttt caagcgctag ccgattatct
     7201 atcgaaaaaa ggattggaat cttcgattga ctggttgttt tgtgatcagc ctgaagcata
     7261 tgttttgaaa cgtgcaactg cgttgagtgt accggcagat tgtttttcac ctaaagaatt
     7321 tgattcaaaa aaagagtatg aagaagcaat tttgcataaa ttgaaagaaa aaaagatcga
     7381 tttgatcgta ttagctggat atatgcgaat cattggaccg gtattgctga aaaattatga
     7441 taaaagaatc atcaatatcc atccgtctct tttacctgcc ttccctggtt tgcatggcat
     7501 acgtgatgcc tttgaagctg gagtaaaaga aacgggtgtc acaattcatt atatcgacca
     7561 aggtgtagat actggaccaa tcatccggca ggaaaaagtg agaattgaac aggaggacac
     7621 gttcgattct ttagaagaaa aaatccatag agtagagcat cgaatctatc cagaagtgat
     7681 tagtgaaatt attgaaaatg gaggctatct gaaatgacaa gagcattgat cagtgtatca
     7741 gataaaactg ggattgtagc attcgcccaa ggtttgattg aacaaggagt agaaatcatt
     7801 tcaacaggag gaacaaagca tgcgttggat aaagctggga tcaaaacgct ttcgatcgaa
     7861 gaagtgacag ggtttcctga aatgatggat ggccgtgtca aaacacttca tcctaaaatc
     7921 catggtggtc ttttaggaag acgcgatctc cctagccata tggaggcaat ggaaacggaa
     7981 aatatccaac caatcgactt tgtttgtgtc aatttatatc ctttcaaaga aacgattatg
     8041 aaaccagatg tcgaaatagc agaagctatt gaaaacattg atatcggtgg tcctagtatg
     8101 ctccgtagtg cagcaaaaaa ccatgaattt gtcacctctg ttgttgatcc atctgactat
     8161 gaagaagtac tttcagaatt acgtcagtat gggcatactt cactttcttt cagacaaaaa
     8221 ctagcggcaa aagtctttcg tcatactgcg gcatatgatg cactgatcgc tcaatactta
     8281 acggattggg tggaagaaaa agaaccggaa aaattgacac ttacgtatga acgaaaacaa
     8341 acgcttcgtt acggtgaaaa tagccatcaa gccgctgcct tttatcagtc cgctcttctg
     8401 gaaaaatatt cgatcgcagc agcaaaacaa ctccatggga aagaactttc ttataataat
     8461 atccgagatg cagatgctgc gctacggatc atgaaggaat atgacgagcc aacggtagtc
     8521 gccttgaaac acatgaatcc ttgtggtatt gggacagcat ctacgatttt agaagcgtgg
     8581 gaagcagcgt atgaagcaga tcctgtttca atctttggtg ggatcatcgt tttgaatcga
     8641 gaagtagatc tgccaacagc agaacagatg cataagctgt ttctagaaat catcattgcc
     8701 ccttcttata cacaagaagc tttggaatta ctgcaaaaaa agaaaaacat ccgattactg
     8761 acagtagact ttgcgcagga agaaaatcaa aatcgagaag aaacggtctc agtcttaggt
     8821 ggacttcttg tacaagatca agatctggca atagaaaatg aagaagagtg gaaagtcgtg
     8881 acaaaacgta agccgactcc agcagaagca aaagcattag cgtttgcttg gagagctgtc
     8941 aaacatgtga aatctaatgc gatcgtactg gcaaacgaac gtcagacagt aggaatcgga
     9001 gccgggcaga tgaatcgagt cggttcagta aaaattgcga ttgaacaagc gcaagagaaa
     9061 atggaaggtg cagttttagc tagcgatgct tattttccaa tggatgattc ggttgaatat
     9121 gcagccaaac atggtataaa agcaatcatt cagccaggag gaagcatcaa agaccaagat
     9181 tctattgata tggcgaataa atacgatcta gcaatggtct ttactgatgt tcggcatttt
     9241 agacattaga gaggagtcgg ataaatgaac attttggtga tcggtgcagg tggtcgtgaa
     9301 catgcaataa gtaaaaaact tttagccagt ccgaaggtgg atacggtgta ttgtgcgcca
     9361 ggaaatccgg ggatgacaaa agatggtatc aattgtgtcg ctatcagtga gcgagatcat
     9421 tcagcgttaa tccattttgt taagaaagag gctattgatt ggagtatcgt tggtcctgaa
     9481 gttcctttgt taaatgggat cgtcgatgat tttatggcgg aaggattgaa aatcttcggt
     9541 ccgacaaaag cagcagctct gatcgaaggt tcgaaaagtt ttgctaaaca attaatggat
     9601 acttatcaaa tcccgacagc taaatccaga agttttgaat gttacgaaaa agcagcagcg
     9661 tatatcaaag aaaatggtgc gccaatcgta gtgaaagcgg acggcttagc agctgggaaa
     9721 ggtgtagtcg tggctaccac agtgaaggaa gcgctggatg cggcagaaca aatgttgaac
     9781 cagcatcgat ttggggatag tagcaaaaaa atcgtcgtag aagagttttt ggcaggagaa
     9841 gaattctccc ttttggcgtt tgtccgtaat accaaggtgt atccgatggt catttcgcaa
     9901 gatcataagc gggcatttga taacgataaa gggccaaata caggcggaat gggtgcttat
     9961 tcaccagtac cgcaaatttc aaaaaagatg attgaaaaag ctgtggaaga agttttaaaa
    10021 ccagcggctt tgggaatgaa agaactagga cgctctttca cgggtgtttt atatgcgggt
    10081 ttgattgcta cgaaggaagg accaaaagtg atcgaattca atgcgcgttt cggtgatcct
    10141 gaaacgcaag tcgttctttc tcggttgaag agtgactttg cgcaagtaat cgatgattta
    10201 ttagagaatc gtacagtaga gttaaagtgg cagcaagaag gatacaatgt aggcgttgtg
    10261 gttgcagctg ccggttaccc cgaagaatat gagacaggaa tggttctacc agattttctg
    10321 gaagaagagc tttctgttta ctatgctgga gtttcctcaa ataacggcaa actagttgga
    10381 gcaggaggac gtctttattt agtagaagca tacggtgaga cgatcaaaga agcacagaaa
    10441 aaaatttaca ccgcgttaat ggataaaacg acagatggaa cattttatcg tacagatatt
    10501 ggagaaaaag ctgccaatag cgaactgatc gtgaagtaaa tcagctgctt ccatttataa
    10561 aaaatacaac aaacataatc ggaagcgccg attttagtga agccttttca taaagagtgt
    10621 ggtacacttt tgttgtgtat ataaataagg aggagttcag atgaaaaaaa ttcaattagg
    10681 tacttctgat cagaaagcag ctgcagtgat cttaggctgt atgcgtatca acaatgcgga
    10741 agatccagta aaagtgattg agacagctta tgaaaacggc attgattttt ttgaccatgc
    10801 agatatttat ggaaacggtg aatgtgaaga aatctttgca gatgctctag caaaaacatc
    10861 aatcaaacga gaagatcttt ttattcaaac aaaatgtgga atcgttccag gtgtgatgtt
    10921 tgatttttct aaaaaacata tcattgaatc tgtagaaaaa agtttgaccc gtctgaaaat
    10981 ggattatgtg gatgctttac ttcttcatcg tccagataca ttggtagaac cagaggaagt
    11041 agctgaagcg tttgatgaat tggaacggtc aggaaaagtt cgttattttg gcgtcagcaa
    11101 tcaaaaacca atgcaaatcg aattgctgaa aaaatatgtt cgtcaaccat tagtagctaa
    11161 tcagctgcaa tttggcttga aacatactgg aatgatcgat caagggattc atgtcaatat
    11221 gacagatgaa gcaagtatcg atcatgacgg tagtgtactt gattattccc gattgcatga
    11281 tatgacgatc caagcatggt caccatacca gtatggattt tttgaaggtg tatttatcgg
    11341 gaacgaaaaa ttccctgaat taaaccaaac attagaagaa ctagcagcta aatatcaaac
    11401 gacaccaact ggcttggctt ctgcttggat tttacgccat ccagccaata tgcaagtgat
    11461 cgccggtacg atgaacgtag ggcgaatcaa ggaaatcgct caagcttcag aaattaatat
    11521 gtctcgggaa gattggtacg aattgtaccg tgctgctgga aacattttac cttaaagatt
    11581 gtcataagca ggtcaaaagg gctataaatt aaaaagacag aataacttga aagctgtttt
    11641 cagcttcgag atattctgtc tttttttatt gcaaatggaa agagtatcat tgtacggatt
    11701 tcgtttatta gttatttttg tttttaagga aaagctgtgt ccgatattct tttggagaaa
    11761 tcccttgttt tttcttaaat aaataactga aatagttagg gtcattataa ccaatttcaa
    11821 aagcaatatc tgaaatacga tagtctgatt gctgcaataa tttttttgct aattcgattc
    11881 tttgttctgt cagataatcg atgaatgttt ggttaaacga ttgagaaaaa atcgtactga
    11941 aatgagaggg acttaatgca acttgttgag cgacccaagt taaggacata tctggatcgg
    12001 taaaattttc tttgataaaa tccaatgcat ggttcaaaat tggctgatat ttgttccttg
    12061 aaggctgtga gggcagagca gttaagaaag aaatgaacat ataaactgtc gaacggtaaa
    12121 gcgagtcgtc ggcgctgatt gctaagcgtt gactggtgga tgtgcaatga accatttctt
    12181 gcgggatttt cttttctttc aggcagacat gctggagtag cttagtcaag acaaataaac
    12241 gatataatcg tgttcgagtt ggtgtgcctt gtggtttcgt caagtgttcg atgtacttag
    12301 atacttcgtt tttcgataat gaagacaaat caagtgagag gtcaaagtaa aagacagaat
    12361 caactggaag tttcgcttct tgaatcaaat cctcatagct gataatttgt tctttaaggg
    12421 aactggcggt ttcaagtatc atctgcgtga tctcaaaaga tgcaggtaat tcgctgattc
    12481 tttctgcgac aggaccaatg gcgacagaaa aattattttt ttgtcccttt tctaattcat
    12541 ggaccaacgt ttgggctacc tgataactgg tctcgatcac attttcttca agagaatcaa
    12601 ctattaaaaa tttgatgaat cgagaggaaa cagcagagaa gatcacttgt tgattctccc
    12661 taaataaaaa cttcaaataa tcactgagat gagcgtaatc ttcaaagtct gtactgactt
    12721 ggtttgctgc taataatacg gtcatttttt tccctgctaa agagcgattg aaagattcag
    12781 caagtttcaa tgtttcactg atcgtaagtg agcctttgaa caaaccgttc aagaaatgat
    12841 tttttttcaa ttcgaaaaca agatcagaag aagtgtgcgt ttctttttgc tgcaaatcta
    12901 aagcagttac tgctttttct attgcttgtt tcaattcgct acttttaatc ggtttaagca
    12961 gataatcatc tgcctgtacc tggattgctc ctttcatata atcgaaatcg tcgaatccac
    13021 taataaatat gagacgagtc caaggaagta gtttccttgc ttcttttgaa aaagtcaacc
    13081 cgtccatgaa aggcatttgg atatcagtca gaatgatgtc gggctgtaag tcgataattg
    13141 aagacagtgc catctcacca tctccagctt cgccgacata agtgattgga taataagaac
    13201 caaggacagt tatttgttcc cgcaagttat tgcgaatgag gtattcgtct tcgatgataa
    13261 aaactttata catgtttgtt tcctccaatt gttttgggag atagagggat catcagtgtg
    13321 acagttgttc cttctcggta tttgctgtca atcgtgatag gtttttgatc atttccgtaa
    13381 taaagaagga gacgcttgtt tacgttgtaa agtccgtagc cgatactgaa atctgaatcg
    13441 atccctttgg ctaactcttt acgtatttct gccagttttt ctgcagggat gccaatcccg
    13501 ttgtctataa ctttgaattg gatcatctca tcaattttgc atgtggtaat acgaataaat
    13561 cctttgtgac ggacgtactt cgttccatgg tatacagcat tttcaatcaa tggctgcaag
    13621 atcattttta aaatagaaac aggaaaaagt gtttctggta tatcgatctt atagtcaagc
    13681 atatggccgt atcttatttt taagatgact agataatcat tgatatggct aatttctttt
    13741 tcaagaggaa tccagtcttg tcctttgctt aaagacgtac gaaaaaagcc ggaaagtgca
    13801 tgggtcatag tcagagcttc ttcaaagcag tcttgttcga tcaaagaaat aatggcatcc
    13861 aaactgttat aaataaaatg gggagtaatc tgagcttgca atacacgaac ttcactttgt
    13921 gctaaatggt attgtttcaa agcgttctcc cgtaaagact ggtttagatc ttccgccatt
    13981 ttattcatgc tagcggtaag tgtttgtaat tccagtgttt ccggcagggt taaacgaaag
    14041 ccaaggttcc ctgaagaaag ttgttctgac atctcgatca gctgattgat cggttcttgg
    14101 acctttctct ctaaaaagcg acgattcttt ttcgcataga aaaaaatggt actaagaact
    14161 ccaagttcca ctattgttaa tagaatgagc gagcggacaa gtgtcgtatt ttttttgctt
    14221 gctaagtcga tctccacacg aacaaaatct tgtaagatat ctgacagcag ttgagtgaca
    14281 gaatctacct gattgatgat ctcttcattg gtatccataa aatcttttgc caagatatta
    14341 ttgatcagct cgttttgata atcttccagt gtatcgatcg tacgtagcga tacatctaac
    14401 gtactaattt ctttaagtgt atttgtatta tttttgatct ctcgaatatc attcctaagt
    14461 tcttctagga tattttcctc attgaactca tctacggtta cttggccaga aatcaagtcc
    14521 cacatacttt ccaaaacttt ttgatcaacc ttcaaagcaa ttgcatctgc tttttggata
    14581 tttgcgatcg tctgttgata aatcaaaagc tgttgcgaat ataacagtat gctcagtagc
    14641 aaagggataa cagcaaatag aagcatggct ttgtttgctt gggcaaaaat ctgttttatg
    14701 cttaaatttt ttgtcatgat acttctccag tcaataattt ctggttggga tgttagctat
    14761 attctgctgg gaaaagacag tctcggaaat aaaaatatct ttaggtaatg tttttcctgt
    14821 ttgaatattt ccaaaataac gagtaacggt attggctaca taccagccga catcaggttt
    14881 acactcgact acacaattga cgattcctga gcgtagcttc tcgatcatat cttcttgtcc
    14941 atcaatagtt acaatgatca aatcttctcc aggtttgatt gatgtttctt ttatcgcagc
    15001 taaagcaccg tgagtcattt catcactatg gctgtataat acatcgattt cggataaatc
    15061 atttgtttct aaatatcgtt tcatctggtc ttttcctttc atccgaataa aatcaccgac
    15121 aattcggtga acaatagtca tcggaggttt atggtcgatg gttccatctt tttttagggt
    15181 tggtttacga ttgattgatt ccaaaaatcc ttcggagcgt agcttggtcg gtgtggagtt
    15241 ctctgaacca gcaagttcta ggattctgat ttcctgtttc tttgaatttg tgaagtgatt
    15301 gctgacaaat aaacccgccc gatttccttc tgctttgaaa ctggggccaa tgtgggtgac
    15361 gaaaagctcg ggatcattcg tttgaatatg tctgtcgaca agtatgacag ggatccctgc
    15421 tcgctttgct tcttttaata cagagtccca cccggattct tgcaaaggag taaaaatgat
    15481 catatccact ttataggcaa tgaacgtccg tatatcttgg atttgccgtt cctgattcat
    15541 gtagccattt cggtagagaa cttggtaatc ttctttttca agcgcagtga taattgattc
    15601 agtatgcttt ttccgccagc tactctccgt tcctgattgc gaaaaaccaa cgactagtgg
    15661 gtcaggtgct tcctttgtat taggtgtaca ccccatcatt tggtaagcga ttacaacaag
    15721 ggctaaaaaa aataaaacac gtttcacttt aaatcactcc atctggattt gttagtacta
    15781 tcttatcaga taaaagggaa aatcaaagtc aaaaggaatc aatcgaaaaa aatccaagaa
    15841 acttaaaaaa atccaagaca aaaaaagtac acctaaaaaa tttaaagtaa atcccataaa
    15901 aaaatcaatg ttaacgcttt ctttattagc tatactcggt gtatcaattg aaatggggga
    15961 taaaaaatga aaaacaaatt tagaaagatt gttgggacta tcgctatttt gaccgcaagc
    16021 attctattaa gtgcgtgtgg caattcagga tctgcagatg atagtacggg gtatgtagga
    16081 atcgctatgc cgaccaaatc agcagaaaga tggatcgctg atgggaacaa catggtctcg
    16141 gaattagaaa aactgggtta taaaacagat cttcaatatg gagaagataa agtagaaaat
    16201 caagtagcac aaatagaaaa tatgattaca aaaggggtag atacacttgt gattgcttct
    16261 atcgatggtt cggctttaac tgatgtgtta gctaaagcaa aagaagcaga tatcaaggtg
    16321 atcgcctatg atcgtttact gatgaattca gaaaatgtcg attattacgc gacttttgat
    16381 aattttggag taggtgtatc gcaagcagct tatattgaag agcacttagg attgaaagaa
    16441 ggaaaaggac cattcacgat tgaattattt ggtggctcgc ctgacgacaa caacgcacta
    16501 atcaattaca acggagtgat gtctgtttta caaccatata tggacaacgg tcagttggtc
    16561 gtgccatctg gacagacgag tttcagtcaa atcgctacgc ttcgctggga tggttctacg
    16621 gcgcaagcaa ggatggataa tctgttaagc gcaaattata ctgaccaaac attggatgct
    16681 gttttgtcgc catatgatcc aataagttta ggaatcattt cgtcattaaa aggcgtgggg
    16741 tatgggagtg aaagtaaacc tttacctgtg attactggac aagatgcgac agttgctggc
    16801 gttaaatcga tcattgccgg ggaacaaaca caaacgatct ttaaagacac acgtatctta
    16861 gcaaaaaata cgattgaaat gatcaaagca atcagtgatg gagaagaggt tccggtcaat
    16921 gatactgaaa cttatgataa tggggtgaaa actgtcccta cgtatttagc aaatacagta
    16981 tctgtcgata aagataatta tcaagcagag ctgatcgaca ccgattatta taaagaatcc
    17041 gatctgaaaa attaagagga accaaacaag gaactaaaga gatctaagtc agagagagga
    17101 taagaattat ggcggattgt attttaaaaa tggcagatat caccaaaaaa ttttctggaa
    17161 tccgagcgtt agattgcgtg aatctgatga ttgaacgtgg ggaaatccat gcattgtgcg
    17221 gagaaaacgg agcgggaaaa tcaacattga tgaatgtctt gagcggcttg tatccatatg
    17281 gctcctatga cggggaaatc ttttatgatg gaaagctgtg tcaatttaaa gatttgaaag
    17341 atagtgaaga aaaaggcatc gtcatcattc atcaagaatt agcactaagt ccttatcttt
    17401 caataaaaga gaatattttt ctcggaaatg aacaagcaga aagaggcgtg attgattggg
    17461 aactgacaga aaagaaaaca tatgaactgc tgaataaagt cggtttgtct atcgacccga
    17521 atcttctagt atcccagatt ggcgtagggc aacagcaact agttgaaata gctaaagcat
    17581 tatcaaaatc cgtccgtctg ttgattttgg atgagcctac cgctgcattg aatgaagaag
    17641 aaagcgcgaa tttgctgaga ttgatccgag agttgaaaga gcaaggtgta acctccatca
    17701 ttatttcaca taagctgaat gaaatcgtgg atatcgcaga tcgaatcacc attttacggg
    17761 atggacagac gattgagaca ctagaaaatg aaatgatcag cgaagagcat attattcgcg
    17821 gaatggtggg cagagattta gttgatcgtt atcctgaaag aaaaccggat attggagaag
    17881 tttattttaa agtagaagac tggacggtct atcaccctct tgatcacgag cgaatcataa
    17941 acgaccacat caacttgcat ttgaaaaaag gagagattgt aggaatagct ggactgatgg
    18001 gagcgggcag aactgaattc gctatgagtc tatttggaca ttcttatgga agcaagatat
    18061 ccggacgtat attaaaggaa ggggcagaga tatcagttaa gaccgttcct tcagccattg
    18121 caaacggact cgcttatgtc tcggaggacc gaaaatcttt aggactgaat ctgctgatgg
    18181 atattcggga aaacgtgacg ctgagcagtt tggataaaat aagtcaaaaa ggagtattag
    18241 ataaagaaaa agaagtaact gaggcagaaa atttccggaa aaagatgcgt ataaaaacaa
    18301 actccatcca tcaaattgtc agtagtctta gtggtgggaa tcaacaaaaa gtcgttttat
    18361 ccaagtggct gatgacacaa cccgatattc tttttttgga tgagccaacc cgtgggatag
    18421 atgttggggc aaaatatgag atctacacga ttatcgaaga aatggcagca aatggcaaag
    18481 ctgtctgtct tatctcttct gaacttcctg aaatattagg gatgtgtgat cgaatctata
    18541 cgatgaacga aggacgtatt acaggagaag tctcgcgaga agatgcagat caggaagtct
    18601 tgatgaaatt aatgacgaaa gaagaggtgg gttaagttgg aacaggcaaa aaatcttacg
    18661 gataaaaaag agaaaaaact aaatttgaaa agtagagcag ctgatctttt tggtcgctac
    18721 agcatggtga tcattttagc gggactactt attgcgtttc aattgatgac ggatggtatt
    18781 ttctggcgtc cattgaatat aactaacctt gttctgcaaa atagccatat attagtacta
    18841 gctgcaggga tgttattagt tgtgctctta ggtcatgtgg atttgtcggt agggtcagtg
    18901 atggcgtttg ttggtgcaat tgcgggcatg atgatggtca atcgccaaat gaacccgtgg
    18961 atgacagtta tcgcatgtct tgcagtaggc gggctgatcg gcgcatggca aggtttttgg
    19021 gtagcttatg cagggatacc ggcgtttatc gtgactttag caggattgct gatgtttcgt
    19081 ggactgacac aagttgttct aggaggccaa tctctagcac cttttccagc tgttttccaa
    19141 aaaatgtcta cgggttattt accagactta agcgaaggaa gcagccttca cttcttgaca
    19201 ttgattttag gaatgatcat cacgatcgtg ttagttgttg gtcaatggcg aacaagaaat
    19261 cgtcggaaaa atcatttatt tgaagtggaa tctccaacag ctttcttggt aaaggcggta
    19321 tttacagcag tcgttgtact aggaataact tatatctttg cctcttatca agggtatccg
    19381 attattttga tcattcttgg tttgatcgtt gcagcatatg ggtttttgac aaataaaaca
    19441 gtagcaggtc gacagattta tgcgacgggc ggaaatcgaa aagcggctga actatcaggg
    19501 atcaaaacaa agcgaatcac gttctgggta ttcgtcaaca tgggagtcat ggcagcttta
    19561 gctggattag ttttagctgc tcgattgaat gcggcaacac ctcaagcagg tacatcgatg
    19621 gaactggatg caatggcggc agtatatttt ggtggtgctt cgacttccgg cggcattgga
    19681 acaatcatgg gtgcgattgt cggtggcttg gtcatgggtg tattgaacaa tggcatgtcg
    19741 attttaggcg tcggggtaga ctggcagcag gcaatcaaag gattgatctt gcttttagcc
    19801 gttgtgctag acttgtataa taagaaaaaa cgaacaacgt aggagaacgc cggttattca
    19861 gaaaaaagac tgtgacaaga catttgtcac agtctttttt tcgctaaaag cgaacattca
    19921 ttgtttcgtt tgtatagact aaaaataata tatgtttttt taccattcgt ataaattctc
    19981 tttttgctct tgattttttt gcttaattga gttaaattac atagggcgct aaaaaaagcc
    20041 ttgattaaat taataatgtt cgtgttttgc tggatgtgaa catcaggagg ataatgtaat
    20101 gaaagtattt gattacgaag atattcaatt aattcctaat aaatgtatcg taaatagccg
    20161 ttctgaatgt gatacaacgg tcacattagg taaacataca ttcaaaatgc cagtagtgcc
    20221 tgccaacatg cagacgatta ttgatgaaac aatcgcagaa ttcttagcgg aaaatggtta
    20281 tttctatatc atgcatcggt ttgatgaagc agctcgaatt ccgtttatca aaaaaatgaa
    20341 aaagcgtgga ttgattacct cgatcagtgt tggcgtcaag aaagaggaat attcctttat
    20401 agagaagttg gcagaagaat cgctaaatcc tgattatatc actatcgaca tcgcgcatgg
    20461 acatgctaac tcagttattg atatgattca gcatattaaa aaatatttgc ctgaaacttt
    20521 tgtgattgcc ggtaatgttg gtacaccgga agccgtccgt gaattggaaa atgcgggcgc
    20581 agatgcaaca aaagtcggga ttggtccagg aaaagtatgt attacaaaaa tcaagacagg
    20641 ctttgggact ggaggctggc aactggcagc tcttagatgg tgtgcgaaag cagctcgcaa
    20701 gccgatcatc gctgacggtg ggatcagaac acatggcgat attgcaaaat ctgtccgttt
    20761 tggtgcgaca atggtcatga ttggttcatt gtttgccggt cacgaggaat ctcctggcga
    20821 aacaaaagtc gaaaatggaa tcgtgtataa agaatacttt ggttctgctt cagaattcca
    20881 aaaaggcgaa aaacgaaatg ttgaaggaaa gaaaatctgg atccaacaca aaggatcttt
    20941 gaaagataca ctagtggaaa tgcaacaaga ccttcaatca tctatttctt atgctggagg
    21001 aagagatctg gaagccattc gaaaagttga ctatgtcatc gtgaaaaatt cgatttttaa
    21061 tggagacaca atctaaaaaa taaataaaat attaggatgt tgtgaaaaag ttgtcctgca
    21121 ttaagtaata agaacagcca aacaaaaata gttctttata tgttttgttt ggctggaatt
    21181 attatcgcag atacaagctt ttgaacatca ttattcagaa taagggactg tgataagatt
    21241 tttgtcacag tcccttatgt tttgcaaaaa aagtttttct tttttctcgt aaattcggta
    21301 aaatcaaaag aaaaaataga caatagaaaa gagaagctta tgtgggaaaa agtagagaaa
    21361 aaacaaggac cgatttatcg tcaaattatg gaacagatta tgagagaaat cgaaaacgga
    21421 aggatcaatc ctggaagtca acttgaatca gaacgaaaac tagggcaact ttttggtgtg
    21481 aatcgttcca ccgttgtcca tgcattggaa gagcttaggg agcttggggt actaacgagc
    21541 aaacgtggca gcggatggtt tgttaatcag actgaatggg ggaaattcgc tgttccaaga
    21601 atcgattggc ggcaaatgat ctctcctcgt tatgagcaga cggactggta tgagcaaaaa
    21661 ataagagaag caaagcagat ccaaaaaaca tcgtttcttg atttatacgc tagcgagatg
    21721 ccagatgagc ttttgccgaa ttttgagttt ccttcttatt ctcttgaaga aatcttagcg
    21781 gaagaaaaag aaatggatct tttaggctat actccgttac gtaacaaaat caaacggtat
    21841 ttggaaagta aatttgaatt ggcattttcc cccaaccagc ttcttgtgac tggtggcggt
    21901 cagcaagcaa tctttttgat tttacaaacg attctttcag ctggagaggg gatagctgta
    21961 gagtcacctt ctttttttta ccgattacct cttttcaaag cttcaggaac gcgtttattt
    22021 gggataccga tggatgaaga agggatcgac ttagaaaaac tgaaagaatc gatccataaa
    22081 aataaattga aagcagtgct tatcaacccg aattttcaaa accctacagg aaaagtgatg
    22141 agtcaaaaac gacgagaaaa gctagtagaa ttgtgtcgac agtatcggct tccaattatt
    22201 gaagacgatg tatttacgga tctttcattt ctaaaccaag aagaagtcct tcctatacga
    22261 acgattgatc cggataatgt gttatacgtc ggttcgttat ctagggtttt aggaaaaaca
    22321 acgaaaatcg gttgggtgat aggacctgag acttttatct cgcaactagc tcaagcgcaa
    22381 gaaatgatgg agttttcgat gaatatcctt acacaaatca cagtggctaa tgtatttaat
    22441 gaagcaattg atttgaaaat gcaagatgta agaaaaaagt tgaaagaaaa aagccgactg
    22501 ataagcgctt ggggagattc acaatcgttt ttcaagcttc attcaatttt aggtggttac
    22561 tatgcctgga ttacttggga tgggaaaaaa ctagaccccg aactagcaga aaaagtagta
    22621 gatatgggtc ttggaattgc accaagtcta ctttttgggc aagatataaa tggaatcaga
    22681 atcaattaca gtaggctgga tgaaaaccaa ataccgttgt tttattcaaa gatgaaaatt
    22741 ctagaaaagt ggttaacaga ataatttcac aaagtaaata gattaaagaa tataacagct
    22801 tggatttaaa tttcaagctg tttctttttt ttcggaaaaa gaatacgata taaagaaact
    22861 aagaaaaaac cattatttgt acgtccgttc acgatgtgta aataaaataa atgtttgcaa
    22921 caaaactgta taacaccaac gtttttaaat agaaacagat ggttgtaagt ttgattagaa
    22981 aatagaaaaa atgcagatga aatataaaac gctttcctta ttgtgatttt attcactaat
    23041 gctgttaata tgcggattgg cataatttcc tttcatcgtg aaaatttgtg cttttagctt
    23101 gtatttctca taaatccatg ataatttatt aatgaagacg gttaaatagt gatacagttt
    23161 tattcactgt ttcaatcgca gaatgaagag attttcttat agatgagaga ggaatgtgtg
    23221 acaaatggca aacaaaaaag caccgatcga cttccaagca ctgctagatg aagtcaatgc
    23281 agatttccca gtatatcaag cacttgatca agatggaaac gtagttaaca aagatttagt
    23341 acctgattta tccgatgatg aactcgttga attaatgact catatggtat ggtctcgtgt
    23401 attagaccaa cgttcaacag cgctgaaccg ccaaggacgc ctaggctttt ttgcaccaac
    23461 tgctggacaa gaggcaagtc agctggctag tgcttacgca tttgataaag aagatgttct
    23521 tcttccaggt tatcgggatg tacctcaact agtaaaacat ggtttacctt tatctcaagc
    23581 ttttttatgg tctcgaggac atgctgcagg taattcttat ccggaagaat tgaaagctct
    23641 accaccacaa attatcatcg gtgcacaata tgtacaagca gccggtgttg cattaggttt
    23701 gaagaaacga aacaagaaaa atgtcgtctt cacttatact ggtgatggcg gttcatcaca
    23761 aggtgatttt tacgaagcaa tcaatttcgc tggcgcttac catgcaaatg ccgtatttta
    23821 tatccaaaac aacgggtatg cgatctctac acctcgtgaa aaacaaactg cagcaaaaac
    23881 acttgcacaa aaagctgtcg cagctgggat tcctggtatt caagtcgatg gaatggatcc
    23941 gcttgcagta tatactgtat ctaaaatggc acgggaatgg gcgatcagtg gaaatggacc
    24001 agtcctaatc gaaacactga cttatcgtta tggaccacat acactatctg gtgacgatcc
    24061 aacccgctac cgtacaaaag acacagatga cgattggcag aaaaaagatc cattgatccg
    24121 cttccgtaaa tatttgacgg aaaaaggact ttggtctgaa gaaaaagaag aacaagtcat
    24181 cgaagcaact aaagaagaaa tcaaagcagc tattgctgaa gccgacaaag taccaaaaca
    24241 aaaggtttca gatttcttga aaaacatgtt cgaagtatct ccacaatcaa tcaaagaaca
    24301 aattgcaatt tatgaagcga aggagtcgaa ataatcatgg cacaaaaaac aatgatccaa
    24361 gcaatcacag atgccttagc acttgaacta gaaaatgacg agaatgtcgt tgtttttggt
    24421 gaagatgttg ggaaaaacgg aggagttttc cgggcaactg aaggattgca ggaaaagttc
    24481 ggagaagacc gagtattcga tactccttta gctgaatctg gaatcgcagg attgagtttc
    24541 ggtcttgcgt tagaaggatt tcgtccagtt cctgaaatcc aattctttgg ttttattttc
    24601 gaagcaatgg acgaagtagt agctcaaatg gctcgtacaa gatatcgaat gagcggcact
    24661 agaaatctac ccatcacaat tcgttcgcca tttggtggcg gtgttcatac accagaattg
    24721 cattcggata atttagaagg tttgatcgct cagtctcctg gtattcgagt agtgattcct
    24781 tccaaccctt atgatgcaaa aggactattg atttcttcta ttagaagtaa cgatccggtt
    24841 gttttcctag aacacatgaa actatatcgc tcattccgag aagaagtgcc ggatgaagct
    24901 tacgaagttc ctttggataa agcagcagtt actcgtgagg gaacagatgt atctattatc
    24961 acatacggag caatggtgcg tgaagcaatc aaagcagcag acaatcttgc aaaagaaaat
    25021 atatctgttg aaatcattga tcttcgtaca gttgcgccat tagatgtaga aacgatcatt
    25081 caatccgtgg aaaaaactgg tcgcgtagtt gttgtccaag aagcacaacg acaagcgggc
    25141 gttgccgcgc aagtagtttc tgagatctca gaacgcgcta tcctttcatt agaagcccca
    25201 atcggacgag tttctgcacc tgatacagtc ttcccatttg gacaagcaga aaatgtctgg
    25261 ttgccaaatg caaaagatat cgaagacaaa gtaaaagaaa tcgcggaatt ttaagaaaag
    25321 aagggacgaa acaaagtcat ggcttatcaa tttaaatt
//
LOCUS       DAFLWQ010000038        24258 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.039, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000038 DAFLWQ010000000
VERSION     DAFLWQ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.039"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(45..1340)
                     /gene="purB"
                     /locus_tag="L1V16_001549"
     CDS             complement(45..1340)
                     /gene="purB"
                     /locus_tag="L1V16_001549"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBN1275892.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1353..2477)
                     /gene="purK"
                     /locus_tag="L1V16_001550"
     CDS             complement(1353..2477)
                     /gene="purK"
                     /locus_tag="L1V16_001550"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBN1275893.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2470..2958)
                     /gene="purE"
                     /locus_tag="L1V16_001551"
     CDS             complement(2470..2958)
                     /gene="purE"
                     /locus_tag="L1V16_001551"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBN1275894.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3374..4681)
                     /locus_tag="L1V16_001552"
     CDS             complement(3374..4681)
                     /locus_tag="L1V16_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBN1275895.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4684..5265)
                     /locus_tag="L1V16_001553"
     CDS             complement(4684..5265)
                     /locus_tag="L1V16_001553"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBN1275896.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5381..5478)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5837..7129)
                     /locus_tag="L1V16_001554"
     CDS             complement(5837..7129)
                     /locus_tag="L1V16_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1275897.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7126..7749)
                     /locus_tag="L1V16_001555"
     CDS             complement(7126..7749)
                     /locus_tag="L1V16_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275898.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7752..8588)
                     /locus_tag="L1V16_001556"
     CDS             complement(7752..8588)
                     /locus_tag="L1V16_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1275899.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8605..9492)
                     /locus_tag="L1V16_001557"
     CDS             complement(8605..9492)
                     /locus_tag="L1V16_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1275900.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9508..10791)
                     /locus_tag="L1V16_001558"
     CDS             complement(9508..10791)
                     /locus_tag="L1V16_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1275901.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11474..12157)
                     /locus_tag="L1V16_001559"
     CDS             complement(11474..12157)
                     /locus_tag="L1V16_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBN1275902.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12175..12792)
                     /locus_tag="L1V16_001560"
     CDS             complement(12175..12792)
                     /locus_tag="L1V16_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBN1275903.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12802..13626)
                     /locus_tag="L1V16_001561"
     CDS             complement(12802..13626)
                     /locus_tag="L1V16_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBN1275904.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13619..14179)
                     /locus_tag="L1V16_001562"
     CDS             complement(13619..14179)
                     /locus_tag="L1V16_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275905.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14353..15309
                     /locus_tag="L1V16_001563"
     CDS             14353..15309
                     /locus_tag="L1V16_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1275906.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15614..16570)
                     /locus_tag="L1V16_001564"
     CDS             complement(15614..16570)
                     /locus_tag="L1V16_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HBN1275907.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16674..17276
                     /locus_tag="L1V16_001565"
     CDS             16674..17276
                     /locus_tag="L1V16_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBN1275908.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17364..18863)
                     /locus_tag="L1V16_001566"
     CDS             complement(17364..18863)
                     /locus_tag="L1V16_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBN1275909.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18879..19403)
                     /locus_tag="L1V16_001567"
     CDS             complement(18879..19403)
                     /locus_tag="L1V16_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBN1275910.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19701..20450
                     /locus_tag="L1V16_001568"
     CDS             19701..20450
                     /locus_tag="L1V16_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBN1275911.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20441..21226
                     /locus_tag="L1V16_001569"
     CDS             20441..21226
                     /locus_tag="L1V16_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HBN1275912.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21195..21911
                     /locus_tag="L1V16_001570"
     CDS             21195..21911
                     /locus_tag="L1V16_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBN1275913.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22013..23047)
                     /locus_tag="L1V16_001571"
     CDS             complement(22013..23047)
                     /locus_tag="L1V16_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBN1275914.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(23051..24109)
                     /locus_tag="L1V16_001572"
     CDS             complement(23051..24109)
                     /locus_tag="L1V16_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBN1275915.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
BASE COUNT         7188 a         5222 c         4225 g         7623 t
ORIGIN      
        1 tttttgctat tctattttaa ttgaattttg caactcactc ttctttattc caaacctact
       61 cgtttgaata tcacgtcaac gtttttcaaa tgatgatgat aatcaaaggc atcgtctatt
      121 tcttctttag ataataccga tgtgatggtt ggatcttctt ctaacagcgg gcggaactgc
      181 acttggttgt cccaagcgta cgcagttttt ggctgaacaa gatcataagc ttcttctctt
      241 gtcattccct tatcgatcaa tttcagcata acgcgctggc tataaatcaa accaaatgtt
      301 gcagacatat tccgcttcat gttttcagga aagaccgtta gatttttaac gatattgcca
      361 aaacgattta acatgtaatt caataaaatc gtggtatcag gcaagatgat tcgttctgct
      421 gaagaatgag aaatatctct ttcatgccat aatgtgacat tttcataggc agtgaccatg
      481 tgtccgcgca ccactctggc tagaccagcc atattttctg aaccgatcgg attccttttg
      541 tgcggcatag cagaagaacc tttttgacct ttcgcaaaaa attcttctac ttcacgtgtt
      601 tcggattttt gcaatccgcg tatctctgtt gcaaaacgtt caatacttgt agcaataagc
      661 gccatcgctg agaaatattc agcatgtaga tcccgaggga gaacttgagt agagatttct
      721 tgtggacgga tccccaattg tttacataca tactcttcaa taaatggcgg gatatttgcg
      781 aacgttccca ctgctcctga gatttttcct gcttctactc cttttgccgc atgttcaaat
      841 cgttcgatgt tccgtttcat ttctgaatac catgtggcaa gtttcaatcc aaaagtagtt
      901 ggttcagcat ggacaccgtg tgtccgaccc atcatcactg tatatttgtg ttcttttgct
      961 ttttcgccaa tgatttccgt aaaacgtttc aagtcttccc gtaaaatatc atttgcttgc
     1021 ttgatgagat agccataagc agtatctacg acatccgtac ttgttagacc ataatggacc
     1081 cattttcttt cttctcccaa tgtttcagaa accgctcgtg taaacgcaac gacatcatgg
     1141 cgtgttaatt tttcgatttc caagatccga tcgatatcaa atgatgcatg ctcacgaatt
     1201 tttttcacat cttcttgcgg gatttcacca agttctgccc aagcttcatc tgctaaaatc
     1261 tcgacttcga gccacgcacg gtatttgttc tcttccgtcc agatattccc catttcaggg
     1321 cgtgtataac gttctaacat gttttttctc ctctaatccc aaatattcgt ttgtttgatt
     1381 tcttccagcg tttgctggat gtcttctgtc aagatagtga tatgtcccat cttgcgacct
     1441 ttttttgctt gtttttttcc atagaaatgg aattgccagt ctggcttatt ctcaatcaag
     1501 cgatagcttt ccagcagttg ttctcccaaa acattgacca ttactgcatt gcttatcaaa
     1561 cgtacttttt ctcctaatgg ccaaccacaa atacctcgaa tatgggcatc gaactgactc
     1621 atagaacaag cttcaataga ataatgtcca gaattgtgag gacgaggagc taattcattc
     1681 acatatagcc cgcctgtttt tgttaaaaac atttctaccc ctaaaacacc tgaaaggctc
     1741 actgcttctg caatcacacg ggcaatacgc tcagcctcct cgatcacatc ctgatcaatc
     1801 gcggctggag caatcgtttc atgaagaata ttgttgtggt ggatgttttc cacgaccgga
     1861 aaagtcgtga aatctccttg accatttcct gccaccatga tcgaaatctc tttttcaaac
     1921 gggatccatg cttctaaaac acaggttcct tctcttaaaa ggtccatggc aggagctaga
     1981 tccgcccgac ttttcaaaac atactgcccc ttgccatcat agccgcctcg agtggttttc
     2041 aaaacacaag gatagccgat cccgtcaatc gcatcttgga tatccgtcgg actgacgatc
     2101 gttgcataag gagcaatcac gatgttattc gtttccaaaa aagatttttc taacaggcgg
     2161 tcttgcgtaa tcgcaagcaa gtctgtccct tgaggaataa atgacatggg taaaatcgca
     2221 tttaacgcct ctacactgac gttttcgaat tcataggtaa tgacatctgt tcttctggca
     2281 agctctttca gcgcaaaggt gtcatcatag acactttcaa tgtgccaatc tgcaacttgt
     2341 gcggctggac aatcgctcac aggatccagc acacctactt taaagcccat ttcttttgca
     2401 ctaatcgcca tcatacgacc taattgaccg ccaccgacga tcccgatcgt tgaaccaggc
     2461 aacaaaggtt taaccaagtt gatcactact ttctataaca gttttagcca acattgaacg
     2521 tctttcagcc aatttagcct ccaattctaa atcatacatg gaaagcatct gtatcgcaag
     2581 tagtccagca ttaattgctc ccgcttttcc gattgctgta gtagctacag gtactcctcc
     2641 aggcatttgg acaatcgaaa gaagcgaatc caaaccattt aatgttcgtg attggaccgg
     2701 tacaccgata accggcaaag ttgtttttga tgcgaccata cccggcagat gcgcggctcc
     2761 ccctgctcct gcaataatga ttttgattcc tttttttcga gcgttttgtg catattcaaa
     2821 catcaaatct ggggttcgat gagcagaaac gacctttttt tcataagaca caccgaattc
     2881 atccaatatt tgacatgctt ctttcattgt ttcccaatct gaagtactcc ccataatcac
     2941 agagattttt gctgtcattg tttttcctcc cagtttttct acattcatat tttaacaatc
     3001 actttttttg atgtcaaaga aatttcgaat gttaacaaag aaaaacattt tattgttcgt
     3061 gtttattaaa gataaaaaaa aggaatgtga caaaagttag gtcacattcc tttttatgga
     3121 taaacggtgt tctcctgcca actcctcggt cacaaggaac aatattcaac aaacatgaga
     3181 agcttttttt tgaaattgtt ccttgtgact cggagatgaa cggcaggctc acgacctctt
     3241 ccttcaacgg tgttcaatca gctgaccctc ggtattagct caaacaaacg gcaaaatacg
     3301 aggaactatt tttccgtttg tttctctaac aatcaggtca aaacgctgat ttcacaacct
     3361 ttcttttgct ctattacttc ttgaaggctt cttccaatat ttcttcatct tttttcaatc
     3421 cattaaagat caaattcaat atgatagccg taatgctact cattacgatg ccatttccag
     3481 tgaacatttg caatgtttgc ggcatttgac tgaataatgt cggcgtaaca ttgaaaccca
     3541 gcccaaatcc aacagaaaca gcaacaatca atagattttt atcattgctg aaatcaactt
     3601 ccaacagcat acggattcct tggactgcca ccatcccgaa catgactaac attcctccac
     3661 caagtaccgg ctcagggatg atttgtgcta acgcaccgat tttagggaat aatcctaaaa
     3721 caatcaagaa gaatgcagag aaatagatgg gttttcttgt tttgattccc gaaagttgaa
     3781 ccaatccgac attttgagaa aagccagtat aagggaatgt attgaaaata ccgcctaaga
     3841 taacggcaag tccttctgca cgatatccct ttttcaattc ttcttctcca acatttttcc
     3901 cagtaatgtc accaagtgca aaatatacac ctgttgattc taccatgctg accatggaaa
     3961 tgatgatcat tagtaaaatc gaccatacgt cgaaagttgg tttaccaaaa taaaagggtt
     4021 gtggaacatg gaacaacggc gcatctccaa tcgcgctcag atcaatcatt cccatgaaag
     4081 cagctaagat gcttcctccg actaaaccaa tcaataccgc gattgaacga atgaaccctt
     4141 ttgccagcat ttgcacgcct acaattagga gaatcgtcac aaatgcaagt agcagatttg
     4201 ttttgtcacc aaaatcagct gctgttgcat tacctccacc cattttctcg attgctacag
     4261 gaatcaaagt caaaccaata acggtgataa ccgttcctgt tactatagga gggaatagtt
     4321 ttttaatttt agaaaagaca ccagaaacta acacaacaaa gatcccagaa gcgataatag
     4381 atccgtagat agctcctact ccttcattgg ttccgatcaa gatcagtgga gctactgctt
     4441 ggatcgcaca tcctaaaacg acaggcaagc caattccgaa aaatcggtta actgtcaatt
     4501 gcaataatgt cgctaatcca cacataaaga tatcaattga aatcaaataa gtcatctgtt
     4561 cttgattaaa gcctagtcct gtaccgatca aaagaggcac cgctactgct cctgcataca
     4621 tcgctagcag atgctgcagc cctaaaaccg cagcttttcc attttgtgtt tctttttcca
     4681 cgattatgcg tcctcctcaa gaaactcaac ttgtccattc gtcaaggaag caatacgcgc
     4741 aagagaaacg actctcaatc ccatttcttc aagtaactga cgtccatctt ggaaagactt
     4801 ttcgatgacg atcccgattc cttctacttg cgctccagct tgctggcata attcgatcaa
     4861 tccttttgcc gcttgtccgt ttgccaagaa atcgtcgata atcaatactt tgtcttctga
     4921 agataaaaat ttacgagaaa tagaaatcgt acttgtcact tgtttcgtaa aagaataaac
     4981 agaagctgtc aataattctt catccatcgt caaacttttt gcttttctag cgaagatcat
     5041 tggaacatct aattctcttg cagcaaataa agctggtgcg atcccagaag cttcaatggt
     5101 cacaactttc gtgattcctt gttctttaaa tacttctgca aaccgttttc ccatttgttc
     5161 catcaataca gggtctactt ggtgagtgac gaagctgtcg acttttaata cgccctcgcc
     5221 taatatacgt ccgtcttttt gaatacgttc aactaattct ttcactttat ttgctccttt
     5281 atcatttatt aataccgaaa taaccgcttt tgtgcaaaaa cctactatgt ttctgttaaa
     5341 gaaaaacacc ctccacttta tcataagaaa agaagggtga aatagccaat cttttactta
     5401 tagtccagca tttacggtac tggctagaaa ctgtcatcca tattatgacg atatataagt
     5461 aggtatgtaa aactaataat agtgtaaatt cattttcttg caactgtttt gcacgtgaag
     5521 gcagtttgcc atatttgaat aaaaaatgtt gtttcaaata ttgaaaacag tctaacacta
     5581 ctttctgaaa ctgacaacgt ggtttactta tttttttgta aaatctaatg atttttaatg
     5641 cattattcct ttttgttcgg gtttaaatag ttatttttat tttctcctat ctaaaaaagc
     5701 agcccacata aaaagaaggc atgacaaaaa gcatgtcata gccccttttt ccgaataaat
     5761 agtgttcaaa agacagccta tcggcaataa ggcaagattt tataaactac gggaagtaat
     5821 ttccgtaaat ctattcttat tcttttaagc tgacaagctc gtcaatcact actgcttttc
     5881 ctgaagcaat agaatgattt gctgcgattc ctgtcaaaat cgacaaaata ccatctacgt
     5941 gagttgctgc ccgattccac ggatcttctt ctttttcttc accaaataga tcatctaata
     6001 aacgcggatc tcctccgcca tgtccgcccg cttcttgttc gacgattacc tcatatggct
     6061 caccgaacat cggatagaca tggatggact gaagaacggc tgctccttca tcctttttat
     6121 ctccacctgc attgatgtaa gacttttcga tcactttcat ttcgatccgt cctttgctgc
     6181 cattgaaaga aacattgaat ccttcccacg gcatatacgc gtttagcgaa tacgtcaaaa
     6241 tcgcaccagt ttcatatttg accgttacgc ctagtgtatc ttcaatagag atatcatcgg
     6301 aaaatacact gcggtcacga atatatccac tgtctttttc tgcttctaaa tacatttctc
     6361 gcaattcctc attggctgac aggtctatag caaatggatc agctttagct agttcgcttc
     6421 catagcatcg actgtaaaat atttctactc cgcgtttctc cgcattatgc atcccataaa
     6481 agtttaatcc accgaatgca aatacctttt ggggacggct gttcaaccaa aaattcacta
     6541 gatcaaaatg atgggtagat ttatgaacaa gaagcccgcc gctattgtgc ttatttcgat
     6601 gccatcttct gaaataatct gccccgtgtt gcgtatttaa cagccattcg aagtggatag
     6661 aaaacacatc accaatcaca tcactttcta tcagttcctt tatcttcgtg tgatacggtg
     6721 cataacgata attaaaagtg actcgcaggc ttcttcccgt ctgtttttgg accgttatta
     6781 tttcttgagc tttttcctca tcgatagtca gaggtttttc gcaaataaca tcatatcctt
     6841 ttttcattgc acgaatgata taatcatgat gcgttcgatc tactgacgta ataatgactt
     6901 cagccggccg tacgtcatcc agtagttgct caaattgtga tggcatacat gtctttactt
     6961 ttttctgtcc atacttgttc acaagtatcc gatttgcata atccatcctt gtttgagata
     7021 catcacaaaa accgactagt tcacaagttt gatgatacgt agaggcaatt gcctcataaa
     7081 aaaaacgcgc tctcccacca agtccgactt gtacatattt tttcttcatt taaagtcatt
     7141 ctccttttct tttaagcaaa atactgtgac aaatggcagc cctggataca gtaatgcagt
     7201 gagtaaaaaa tcatgctgta tacaccagaa cagtccatac aaaaggcata aataccacag
     7261 aaaccccttg acgttttttg acaacagcca gatattcctt ttgatcaaat aaacaagact
     7321 atctgcttta tcttctttgc agatatcaat tagcgtacta aaaaaactat gggatacaaa
     7381 aagcaacaga cacaatagaa aaggaatcag ataccaagct ccaatctttc ccactaataa
     7441 ataccaatca actgcaaaaa taatgacaaa cagctgaaac aacgtaatga tgaaacacat
     7501 ccgtttgatt tttcctttcc tccaacatac ctttttttct gccaagtaat ggacagatag
     7561 ataataagaa ggatacatca tcaaaaaata aatcagatag acaacacgag cagacagcac
     7621 taatcctaaa gtgaacaaac atcctagaac taaagcgaaa agagcattac tgataagact
     7681 ggttaaaaaa atccgacaga catagtagtt gagcttgtaa agaaacatct cttctattgg
     7741 ctttttcata ttcagccctt cagaccgctt gtactgatcc cctggacaag atatttattg
     7801 aagaataaga aaatcagaaa aaccggtagc agcgacaacg tagacatcgc aaacatactc
     7861 gcgtaagtcg tactagatcc agcgtctgca aataatttga tggcaatcga taccgtgtaa
     7921 gatctcggct tgtttaaata aatcaatggt cccatgaagt cgtcccattt ccaataaaac
     7981 tggatgatga tcgtcgtgat gatcgaaggt ttcagcaaag gaaaaataat tttggtaaag
     8041 acactatact tgctgcatcc gtcaataatc gctgattcat ctaactcttt ggggatgctg
     8101 accatgaatt gcatgatctg gtaaatgaaa aatgcttgtc caaaaaaatg tggtaaaatc
     8161 agcggcacat acgtcccaac caaattcagc cgattgtaaa taataaactg cggaatcaaa
     8221 atcacttgtg caggaatcat catcgttact aacatgacga cgaaccagaa tctttttcct
     8281 ttgaaatcga ttctcgataa tgcgtaagca atacaagtcg agctcagaac tgtccctatc
     8341 gtcgaaactg cagagatgac aaacgaattc ctaaagaaag taaaaaatga aattccagca
     8401 aaccccgccc atccttttgc gtaattttcc cattgaaaag tctctggaat caaattcagc
     8461 gaaccactca taatctcttg atccgtttta aaagaacctg cgatcatcca taagaccgga
     8521 taaatcatga ctagacctaa tagcaaaata aaaccgtatt gaaaccattt cgttactgta
     8581 ttattcattt cttcctcctc tcattcacac aacgacccat ttttttgatg atttgaaaat
     8641 cagaaaggtg acagctccca taatcaacag catgatccac gaaatagcac tagcataccc
     8701 catagaatta aaagaaaaag cttggttata cacataaaga gcataaaagt tcgtggcatc
     8761 attcggacca ccttgggtaa tgataaatgc ctgcgtaaaa gtcataaacg ccgcgattgt
     8821 ctgcataacc aagttataca aaatgatcgg cgaaagaaga ggtaacgtga tcttgtaaaa
     8881 cgtctgccat ttgttcgctc catcgatctc tgccgcttca taatacgagc ctgggatctc
     8941 tttgatacct gcagcaaaga tgatcattgc cgaaccgaat tgccaagcag acatcaaaac
     9001 aagagggatc atgaccagtt tttgatcgct aaaccaggaa agcgcaggtg cgcctaatcg
     9061 ttccaggaaa atattcacta acccgttttt agaaaacaac tcccgccaaa ctagagcgat
     9121 agaaatactg ccaccgatca aactaggcac ataatacaaa gaacgaaaga aagtcgttcc
     9181 tttgatattc ctcgttaaaa gataagcaat caatagacca aagatcagtt tcacaggtac
     9241 agatgcaaat acatagagaa aagtgactcg gatggagttc aaaaaacggg catcactcag
     9301 catctttata taattatcca agccgatcca tgagactgga tttcccaaac gataatcggt
     9361 gaacgaataa taaagtgaca agatcatcgg tatcactgtt atcaatagaa atcctaggat
     9421 gaatggagaa gcaaatacgt aaccgaccac attgtcttga tccaagaacc gttttagttt
     9481 ttcttttttc atgccttcct cctgctgcta tcctagaatg tttgacgcaa actcataaag
     9541 actctctgct gcttcttctg ctgttacttc ttcataaatg actttttcaa ctaaaagatt
     9601 gtattggtct tgaatttccg gattcaaagc actatcaaag acattcactt cgccgttgtc
     9661 catatcggaa atcatttcta aataatcaaa tgtcgcttgc aaagttgcat catctgcacg
     9721 agcgagctgt tctcgaatat tcgacatgat tggtacacca cgttctcctt ttaaaatttc
     9781 attggcttct tcactgtttt gaaagaaatc aataaactta gcagcttctt ctttatgggc
     9841 tgagcttttt gccatactca gcatttgcga agaacgtaaa gggataccag attctccatc
     9901 tgcttttctg cgaggtggat taatcaactg aatctccata tcttcaggag cccctgacaa
     9961 tatttctgtc aactggttac ttgatagaaa caccattgcc gcttctctat ccctaaccgc
    10021 ctgaaaagac agatccgtcg tacttgcagc tccaccacct ggttctggat gggccccttt
    10081 gtctaccaga tttttacgca gctggaaaaa atctgttaga tagtctggat tttcaaatcc
    10141 caagctgtta gatagatctt cccgattata aaaattcaat cctttctcaa cttgtggtat
    10201 ttgaataata cagccagcta taaaatcttc gaatcttgaa atagcataga ttcctaattc
    10261 ttcagtgatt tgatagctga tttgttcaaa ttcatcccat gtccaatttg aagctggttc
    10321 agggatattt aattgttcaa atatattttt attgtaagca atcgcaaacg aattcacccc
    10381 gttagacagt ccaactaatt gcccgtcgta agtcgtcgtt gctaaatagg attcatctgc
    10441 attagaaata tcaattatcc cttgctccac atattcatct aatggttcaa tctgattgat
    10501 gtattgagga aattgattgt tcagttggaa aatgtcccag atatcatctg atgctgctag
    10561 tgtacctaat tttgtgtaat atccttcata atcataaaat tcataatcga tcgtcacatg
    10621 gggatttttt tcttcataaa gctcgattac ttttactgtt gcatcgtgtc ggacttgcga
    10681 accccaccaa gccatgttca gcgtgatttt tttgtcatct tcttgcccac aagccgtcaa
    10741 gaagaataac ataacactta aagctaagat gattctcatt cttttcttca ttctctgcac
    10801 ctctacttcc attgttattt ttcaatatac tgtattttta tacagaacat atttattaaa
    10861 cgatcttttt caaggggaat aaaaaccaag acttgcctta tcgttctgcc taggatgaac
    10921 aactcaatac tttcaagaaa aattagatag tgctgattct tctttcatcg ctaaaaacac
    10981 ttcttgcttc aatgatggga ggataattac gcaaagaaaa aaggatatca gacaactgcc
    11041 caatatcctt gacatagcta aataagcatg cttcttcgtg tgcgctcttc cctaaaaaac
    11101 agaaaaataa ctagtaattc tgtatgaaat taggtacaat atacacgtcg atgcacaagc
    11161 attgactatg gcaacttgat tggtcagttc ccgctgactt ttcaagcccc gacaatttag
    11221 ctgctactaa attgtcgggt gcctttttta gtttttattc gtttttcatt ctatagaaag
    11281 cgcttcaata aatcaagaca tttttttgtt agaatgctaa taataacaaa aggttttaac
    11341 tcttcttatg tacattacag gtaaaaaaac aaaaaaattt ctcttttttt tgaattctga
    11401 acaaatagta ctggagtaca aaagacgagg aagagccact atctgctctt cctcgtcttt
    11461 tgattctcac ctgttattca tgattctttt tctcagtttc ccgatatttt tccattttac
    11521 gactaaaaag ctctccgcta cttggtggcg tatatgtgat ggcatttgct cctgcttgaa
    11581 tggtctcagc aatactttct tccgttggac cacctgtcgc aatgatagga agttcaggat
    11641 attttttacg aaaatggcgt actgcttctg cagtttcttt acctgcactg atattgataa
    11701 tcgaaatacc agctgctaac ttttcatcta tttctgtata tttcgacgtt accgtactga
    11761 taactggaat atcaactact cgacaaactt cttttactgt ctctaaaggc gtaggaccgt
    11821 tcaaaacgac ccctaacgaa ccttgcgctt ctgcgaacat gctcatgtag gaagaacgag
    11881 caccttgtgt caaaccacca cctacaccgg agaaaactgg aatgtcagct gcctcaataa
    11941 tgcttttagt aatcgctgga tgaggtgtaa aaggatacac agcaattact gcattcgcat
    12001 ttgtattacg tatgatcgca atatccgtag taaagatgat cgaacggatc aattttccaa
    12061 atatcttgat cccgcttgct tctaaaatga tttccggtac tcttacgata tcttttctca
    12121 attccgtcat gatttctggc gtaaattgtt ctgccatcag ccacttctcc tttgctatct
    12181 ccggtcatac tgattcaatt gatacgtctc gatgacctgg atgatttttt gcgcataacc
    12241 ggggtctgtc gcataacctg catcttgcaa tgcttgtgcg gcttcctgat agttggtggc
    12301 cgtaatcact ttttcataca gcgcaggatt ccaatctact ccttggacga acagttgtgt
    12361 atggtcatcc atggactgtt cccatgaatc atacactttg aagtctcctt ggatagttat
    12421 ccattcttcg ttaacaaatt cctttgtttc caggcttact ttcttctgat ccccataagc
    12481 cttgatcccg aaaagattat tgtatttgct agccaaggta ctttttcccc aatttgattc
    12541 taatatagct tgtcctaaaa tgatactagg aagcactcca taaccatctt gtagttcttg
    12601 ggcatgcgga acaagccgtt caataaattg ctgatgggat tgcgcttcat tttcttgctg
    12661 attatcagta aaaggagaag acagattctt caaggaaaaa acaaaggcta agagtatcac
    12721 tgctacaccg gcaaccactg ctggccaacg gatattcttg cgcttttgct ttttccactt
    12781 ttttttcgcc atgatcaatt cctacttttc atttaattca ttcagatatt cttctagcgt
    12841 caattggtgt ttggtgatat actcagcgtt ttctttaccg acataacgta agtgccaagg
    12901 ttcatatgtg atcttagtta tatcttcgtg tccttttgga taacgaacga taaatccata
    12961 ctgcgcagca ttatctgcga tccatttagc tccaggctga tctccgtaac ttgcatccaa
    13021 tacagtagaa ggataactgt tgtaccagtt ttgatcgacg acatcgactg ccagacctgt
    13081 gtggtgttcg ctgtatcctg gctccgtaat cgtttcttta gtaatctttg tcgcctcctc
    13141 ttctgataca ccttgacgac tcatcacatc ttggacattt tgttcgaaaa cttgttgttg
    13201 ggatgataca gaccggtaag ctgagaccat cactaatgga aatccagctg cttcagcagc
    13261 cttggcaaat gcttcatatt ctggagcaat gcgtttgtcg atcaagtatc cgttacttaa
    13321 tgatgccaat tgagtagact catcaatttc tttttctaat ttgtgatctg gaccaaccaa
    13381 aactagcttc caatcgtctg ttttaacatc tggcaattgt ttggacgtac gatcttttgt
    13441 ttctttgtcc tttaccttgc tgctggttgt ttgactgttc ttttctttac tagcagttgt
    13501 tttggtgctt gttcgttcga ctgcttgatt gccggcttga acatgcgaat catcatcgct
    13561 aaaaataaca tagcccattg ctgcgatcat aatcacaact gctccaaatc ctaaaaattt
    13621 attcacttga aaaatccttt cgttgttctt cacgttcccc attcgcctca tgaacgtaag
    13681 tttcttccag attttcattc acccaatcga gaagttcgat tttttctcct tcgatctgtt
    13741 tttgaacatc tgctggcaga cgaaaattca aaatatcatc atagccccat tcatcatatt
    13801 gaatacttac tttcaagtca aggtatctac cagcctgctg attatttttc aaagggatca
    13861 gctcgacttt tgctgctttg ctgctaagcc atttttgcgc gatgcgtgtt ttgatttgct
    13921 tgtactctgc aacggcaacg tttcgttttt cgggaaaaat aatcgtttga cgcaaaatct
    13981 tttgcgttag catccattca taatcagtga aaagattttt tactttctgc atcgcttcag
    14041 atggcagatt tttctcgcca tctttccatt tttgccattg ttctggactg atcagcaagt
    14101 attcatctaa aaaatttttt tcagtttcaa actgttctaa taatacactc ataataagat
    14161 caatatatac ttgatgcacg tttatcccct ccttttaact attctactta agttttgatc
    14221 aaaaagcacc tcttaaatcg ctgctttcat tttttttaat gtttcaagtc ctctcctctt
    14281 tattcttcgt gatttttgtt ataataatag acagacaaga aactcaatcc aactatgaag
    14341 gagcgttttc agatgaaaaa atatcaatgg ggaatcgttg gtcttggtac catcgcacat
    14401 gagtttgccg aaagcttcaa tcaagagacg agcgaactaa cagcagttgc ttccagaact
    14461 tcagaaaaag cggaaaactt cgctcaccgt tacaatattc caaaagctta cggaagctat
    14521 caagaaatgt tagacgatgc tgaaatcgac atcgtgtaca ttgctgtacc aaatagacag
    14581 catatcgacc atatcttggc agcattggaa gcaggcaaac acgttctatg tgaaaaagcc
    14641 atcacgatga ataaaaaaga actggctgac gctatgcgct tagcagaaga aaagaatttg
    14701 atcttagcag aagcgatgac aatcttcaac atgccacttt atcagcagtt acgctcaata
    14761 atggatacag gaaaactggg ggctttaaaa atgatccaag cacctttcgg cagttacaaa
    14821 gaaccagacc ctaaaaaccg gttcttcaat ccagaattag ctggaggagc tctgttggat
    14881 atcggtacgt atgctgtatc tttcgctcgt ttctttttga gctctcaacc tgaagtagtt
    14941 gcctctacaa tggttccttt tgaaacaggc gtggacgaac aatccgtcac tatcttgcgt
    15001 aacaaagaaa atgaacttgc tgctgtcagc ttgacttttc aggcaaaaat gccaaaagtc
    15061 ggtatcgttg cctttgagaa cggttatgtg acgattgctg attacccgcg tgctgatcgt
    15121 gcggagatct tatttacaga tggtacaaag gaattcatcg aaagcgggaa tacatctgaa
    15181 gcaatgaatt acgaaataaa gaatatggta cacatgattg aaggtgactt gcccaatcgc
    15241 tctctcttct tgacaaaaga tgtcatcgaa atcttggatc aaatgcaagt tctatggaaa
    15301 aatatgtaat tttaaaaggt tgtgaaaaag ctgttctgca tcaagtaata agaacagcca
    15361 aacaaaaata gctcctccta tttttcgttt ggctggactt attaccgcag aggaaagctt
    15421 ttgaacaccg tttaagaaag aggttgtgag cctaccgttc agctccgagt cacaaggagc
    15481 aatttcaaaa aacagcttct catgtttgtt gaatattgtg acttgtgacc gaggagttga
    15541 caggagaaca ccgtttaaag aagaggttgt gaaatcagct ttttgacctg aatattagct
    15601 gaattcacaa cctctatttt tggatttttt gttgggagaa ttctgccttg atttcaataa
    15661 aacttttaaa agactgcaaa aactggaaca attctgctcg atcctcgaat tcagggcgac
    15721 tagtcggcag aggcatttgc cgatacaata cataaacttc ttcaatacgt gttaaaattt
    15781 gtctgccatc atttgactct gaaaatgttt ctgcagtata aatcaataaa ccatagatat
    15841 gttttccata ataagctggt tgctggattc tctctagatt ttccagcatg tctttaatca
    15901 cattggcctg tgctcttctc atagagaagt aagtttcgta gtatagcggc tgtctgagcc
    15961 agtagttttc ttgatgttct ctggcatctt cttggctttc gcgaatgaat gtcagtaaat
    16021 gttcgcattt gatctgcaca tcttctttat tttctgataa aagaaattct gccatttgtc
    16081 tcaaaatatt tcgaaattct ttttcgatct gtatttggtt ttccttcagc tgcttcgtac
    16141 gatctggcat gtaaacattt gcaagcaaag caaatactaa tccaatcgcc attaatcccg
    16201 cttcattgcc gatcagctgc caagacatgt tttcctccac taaataatga gtgaccaaaa
    16261 ccgaatttac tactatccct tcggttaatt tgaagcgaga ggcaagcggg atgaacagga
    16321 ataaaaaaag actgaagcca aaaatagtat acccaacagc aaaaaaactg aacagtgctg
    16381 ttgccgtagc taatataaag gctgcgattc gattcatgcc cgtacgcaat gtagagcgct
    16441 tggtatttcc tacacttaat aatgcaatga tccctgcagc tggccaatac aacagcgata
    16501 agctacccgc tgtgaccatc gaaaagaaga cactgatcac tgttttgact gttcgcattc
    16561 ctatacgcat ttacttcccc cttttttatt ttaattatac ttgaataatg aaaaactagc
    16621 tatcagacaa aagtttaggt atgatagtaa aaagaccaaa aaggagaatc tctatgcaat
    16681 ttggccgttt tcgactaggt atgcgtacga tcaaaagtgc cttagctgtt tttttatgta
    16741 tcttgttttt tcatttgact caacgaggaa tcccgatgat tgctgcatta tctgctgttt
    16801 tttctttgcg tcaggacttg actacaaccg tttcttttgg aaagtctagg atcatcggca
    16861 atacattagg tggtacatta gctatcattt atttttttgt caaaagctat tttcacaatg
    16921 attttttggt agaattgatc ttgcttccta ttctagttat tattgtgatc gtcgtgtcag
    16981 atggtattaa caataattcc ggtatcattt ccgcaatagc tacgttgttg ctgattgcgt
    17041 tgagcatccc tcaaggcgaa tccgctttgt atgctatcca acgtgtacta gatactttta
    17101 tagggacatt cattgcaatc ggtatcaatt tctttcttcg tcctcctgaa acagaaaaga
    17161 aggaagaact atcagaagat ttggtcgaac tccaaaagaa agaacgattg ctaagaacaa
    17221 atttacaaga gatagaagct aagatccaaa aacaaaagaa aaatagcgag gactaatttt
    17281 cttttgcaat aaaataaaaa aatggagaga agaactttaa aaagtcttcc tccatttttg
    17341 attgaacggt gaagtgtact actttattct tccttcatcg agttttgttc tgcctctttt
    17401 ggcgcttcat acatatttac ttggctagta gtcccacgtg tcgacaaatt ctctacgatt
    17461 tccttcaagt caagtcctgt tgtcgctttt agtgtttctt gagtagaaga aagcaaattt
    17521 gtggcataat ttgtcactcg gttcgctcca ctggtttctc ctgaactgct tcctgtatcg
    17581 acaacagaga ttttttcgat atttcctagc ggctgtgctg cttcgcgcat caattgcggt
    17641 agcatatcga taaccatact caagacagct gcttcgccat attccttgaa ggcattggcg
    17701 atcttttgtt ttgcttcggc ttctgctttt ccttttgcta gtgctgcttc ggcttctgct
    17761 tgtccagcta aacgtgtctt attggcttcc gcttctgcca gtgcttccac acggaatcgt
    17821 tctgcttcgg cttcagtcac ttctttgact ttttgagctt gtgcttcttg ttctttagcg
    17881 taccgatcgg catctgcttt tttcttcact tccgaatcat attgcttttc acgacgtgtg
    17941 atttcttttt cttccagttc gatttgtttt tgacgttcta cgattttaat ctgcatttcc
    18001 tgttcgatta cttgttgttg tgctcgggca ctttctaaat tgtaggcttg gtctgctttt
    18061 gctttagcaa catcttgttc ttgtttgtag gttgctaatt tcagttcttt ttcttttaat
    18121 gattctgcga tctctgtttg tcgctgtaat tcagctgctt gtgattcttt ttctgcttga
    18181 gcttttttga tacgcgtttc ttttagagct tccgcttctg ctatatctgc atctcttttg
    18241 acttgggcga ttcttggttt ccctaaagag tcaagataac cgtttttgtc tctgacctct
    18301 ttgatagtga aagaaacgat gatcaacccc atttttgcaa ggtctacaga agcgacttct
    18361 tgtacgcttt gactgaactt atcgcgattt tgatagattt cttctacagt catagaacca
    18421 agaatcgagc gcaagtgtcc ttctaatact tctcttgctt cattttccag ttcttctctt
    18481 gtcttgccta aaaactgttc tgctgctgta gcaatctctt ctacagatga accgattttg
    18541 atgatcgaag taccatcaca catcaccggt acgccttgtt ccgtatacac ttcaggggtg
    18601 gagacgtcca atttactcga taatagactg atccgattcg aacgttgaaa aactggcaag
    18661 acgaatgcgc cacctccacg cacaattttg attttgttat tgctttcatc aatgtgcaca
    18721 tttttgcttc ctaaataact tccactgatg atcaacgctt catccggttt tgctgtctgg
    18781 tacttcgcta caaagacgat cagcaacatc agtaaaatca aagctgcgat tgcgatcgcg
    18841 ataaaaacaa ctggtatttc catttaacac acgctccttt aagcttttat catgctttca
    18901 taaggcatga cataacagat tctttccttg atctcaatga tcaatacttt cgttccccgc
    18961 tcagctgtct gttcttgggg gctgtaaaaa caagctggac gactaatgga accggtaaca
    19021 cttttcaact gaatttctcc catacctcgt acagggatcg gtgtgatcac aacagctact
    19081 tgtccttcca gagttttttc agaagacgac atcgttgatt cggcatgttt catcggcatc
    19141 aatatataga aattaagcaa aaataccaac actatcgata tgcctccact agcaataaat
    19201 aaaaataaag atgattgatc tgttaaacgc tcacctagaa aaccaaataa gcttgtgaaa
    19261 gttaaccaag ggataataag catcggatca agcgggccat caaaatcgaa tacatctcca
    19321 aaaataatca ataggactgc caatcctgca caaatcagca atgtatacca ataaatcgtc
    19381 tcaagtgcga ttccccctat catatacacg cctccttcca tttctacgtc tatcatacca
    19441 atgtttgaaa attctgtata gcttctttta ccgactcagt ggtgtttttt ataggaaggt
    19501 tgtgtttatc gttgacaatt tgttaaattt ttgttttcat gttaaaattt tcacaataaa
    19561 ttctttcgag gtagcctatg tttccttttt ttaagaaaaa accattaaag ctccagaaca
    19621 cgatcatcct tgtcgtttgt ttctccacat tcgtttcttt gattgtttct gccatattga
    19681 tcaggaattt tattctttcg atgaaccgat ctagtgtgtc agataaaatc tctagcattg
    19741 ctaaaatcgt tgccaatgat aaactcatcc aaaaaaagct gcagactggt gacccgacac
    19801 atgcgattca aggaataaca aatgaaatca tgattgcatc gaatttagat tttatcgttg
    19861 tcatggaccc tgaaggcatt cgatattctc acgcagaccc aagttacatc ggtcttcctt
    19921 tctcaagtca tgaagatgtg aaaaaagtga ttggaggaca agaatttttc tctgaaaaag
    19981 aaggaatgtt agggttcggc ttccgctatt tcgtccctat ttattatgat caagagatta
    20041 ttggtgcagt ttgtgttggc ttaacaaaca acacgattga caatcaagtc aaagatggac
    20101 aaaaaatgat tgttttttca ttgattattg gacttagcgt aggcatcata ggcgccgttt
    20161 ttcttgccca aaaaatgaaa aaagtactgc ttggacttga accacaagaa atagcagaac
    20221 agttaagtga aaaaacgatt atcgaaaatg aagtagatga aggaatctta gccatctctt
    20281 ctgataaaac tatcctcttg atcaatacac ctgcaaaaaa cattttctac caaacagagc
    20341 agctattgga tttcgaagta ggaaaaaaat cagtgataat ctatatgacg ttttgtttaa
    20401 agagacgatt gagcatcaaa cgaccgttcg gactcaatcc atgtatttaa atgggataga
    20461 aactatttct agcgttacac ctctttttag caatgaccgt tttttaggag cagtcgcaac
    20521 tttacgaaat cgatcagaag taatgaaatt aatggaggag cttgggggga cgaaacaata
    20581 tataaactcc atgagagctc aaacccatga attcatgaat aaacttcatg tcatttctgg
    20641 tttgattgat ttgaagaagt atgaagaagt cacccatttt atccagcagc taaatcaaaa
    20701 ttataaaaaa gagattggcc aagtctcaag tctgatcaaa gtacctgcaa ttgccggttt
    20761 tttattaggc aaaataaacg aagccaaaga acaatctgtt gaaatgctgt tagaaagcga
    20821 ttcttttatc cctaaaatgg agatggatga ctccatccat tcacttttgc aagtgttagg
    20881 gaacttactt gataatgcaa aagaagccgt gctacaaaaa catgaaagaa acggacaggt
    20941 ccggattcat ttaaactatg acacagaagc tgaagtattc atcgtgaccg tctgcgatga
    21001 cggtgtcggg atatcagaag aaatctcaga aaaaatattt acgctaggtt tttcgacgaa
    21061 gggaatcaat cgtgggtttg gattgaatct catccattca atcgtcaaac gccacggtgg
    21121 atttttagaa ttttccaaac aaacaaatgg cggtacaatc gtctatctag aattaccaaa
    21181 aaaggaagat caaaatgatg acaaatgtcc tgataatcga agatgatcca atggttgcag
    21241 aattgaatcg tacttttgtg gaaagcatcc ctaatatgaa cgtaatcgaa agtttcagaa
    21301 atgtagaaga aggaaaaaaa tatttcagac aaaaaaacgc agatctgctg ctgcttgatg
    21361 tatacatgcc tggcgaaagt ggtatccatt ttttatcttg gcttagacag caaggaaatg
    21421 atatcccagt gattttgatc actgctgcag atgatatcga aaccataaag aatgtgatcc
    21481 gctacggtgc cttagattat ttgatcaaac cgttcacttt gcaacgtttt cagctggcga
    21541 tcgaaaagta tcttgctttc tctcagacaa tccaaacgac tgaaaaagcc gatcagaaat
    21601 tgatcgatca agtattcaac cacaccactc ccattcacga aataccatca ttcatcgatt
    21661 tgcctaaagg tctgtcaaaa ctgactttaa aaaaaataag tgcatttatt ctaaaagaag
    21721 atactatttt ttcaacaaaa gaactggctc aaaaaagctc actgtcacgt atatccgtca
    21781 agaaatattt gaatttttta gtagaacaag atatattgaa cgaaagaatc aaatatttgg
    21841 aaatcggccg gccgctaacc tgttatgaat tgacaaagaa tgggcggaaa aagctcacag
    21901 attactgttg agtcatcgaa ttatcccata caaaatagtc caagtataca gaagtaacaa
    21961 ctgtttactt ggactatttt taaacatttt attgacgaat atccatgttt tcttatctta
    22021 attgacgggc tttaggaaga gatacctcat ttttcgtttt tccagtttct attatttcac
    22081 gaaagttctc gaaacttgtc gaaatcatat ttgataatgc ctcatctgta tttgaaccta
    22141 catgcggggt tacaagaact ctagggtaca tttctactaa ttgctggata gcagggtctg
    22201 gaatcgtctc ccatggcttg aaggatcgga aaaaaacctc tgtttcattt gcaaaaacat
    22261 cggttgcaaa accagctaaa tgattgcttt tcaaagctct taaaatagct tcattatctt
    22321 gaagctctcc acgggctgta ttaatcaaga tgctaccttt tttcatttga gctaaaaatc
    22381 cttcattgat catttgatcg ttttcacctg ggatatgagg tacatgaata ctgacaatat
    22441 cgcttttggc taataactct tcaagcgagt ggaacgtcaa tactttttta gcagcttctg
    22501 tctgatgaat atcgtagccg atcactttgg ctcctagtcc cttaaacaaa acagcttccg
    22561 tcaaccctat cctgcctgtt cctatgatcc ctactgtgca atttctgatt tcacgactaa
    22621 acatttgctc atccactcga aaatctttga aagatgttcg gatcgtcgta tacgcagtat
    22681 ttctcaaaag catcatggca aaagtcaaag ataactctgc tatcgcattt ggcgaatacg
    22741 atggtacacg ggctactgtc ataccaaaat cagctgccgc ttgtagatcg atatgattga
    22801 ctcccacagt ccgtgtaaaa acataacgaa tcccatattc ctgcattttt gcaagattgg
    22861 tctcatctgc tatacaattt cccctcaaca atacagcatc atggtccttt gctgacacga
    22921 tattgtcatg tgtcaacagt tcttcataaa gactgagatc ataatggtaa atattcaatt
    22981 tttcaaaaaa atctatctcg ttcggacgaa caccgtaaca tgcgattctc atactttctt
    23041 cctccatttc ttatgaaaat aaacctatgc catgaatcat ttgtaataca acgatccata
    23101 caggtgtcag taccacagca aaaatagttg acagtaagga tgcattggag gctaaaagtg
    23161 cctccctatc aaaactgata gcataggctg ctgccactgt tgcagctggt gtagccatca
    23221 tgataacgat tgttgccagt gcttcaaaat tgactggtag aatattcgtt gccgtcaaaa
    23281 ctgctagaat cacgatattc aatgcaggta caaataccac tttgactaga ctgtaatacc
    23341 atgaagtttt ttcagatgca gcttttttga agcttacttc acctaatgtt gcgccgattg
    23401 ctagccacgc caatggtgaa cttaaaccag ctaaataatc catcggctga aatagccacg
    23461 gtgcagtctg gtcaattcgc aaaaacgcta cttggcttat ctctccttct gcacctgtaa
    23521 ctgacacttg tggcagatac ccttggaaca gccaaatgaa aaggccggca aaagtagcga
    23581 taatgattgg attgacgaac atcgctttga tatttttagc ttccatcttc aagccactca
    23641 tttttatgta tccataagaa tacaaaaaga ttcggtagcc aatattgaaa attgaggaat
    23701 acatcacgcc gacaggacca taaatcgcac tgacgatagg cgttccgaaa aaggtcgtag
    23761 aaccaaagat cgtcaggaca cgcaacgttg tttgcttatc ccctttatag cttaagaaaa
    23821 aaggttttga aactagaata agaataatat aaataactaa tccccaaatc aagacattga
    23881 ttccttgcat cagtaattct gtattgatat cttgcatgaa agctcgaaat gccagtgctg
    23941 gcaaagccac tgttaagacg actttcgata gaatttttcc aacagattca gaaaaaatcc
    24001 ccttttttct acaaacaaac cctaataata taataaaaac tgttgaagtg attgcactga
    24061 caatcgacat atctgtcaaa gtcgatcgaa aaatgtcaaa taagttcatc tttctcctcc
    24121 taattatgtt catttattca caataaaaaa agcttttatt ttgctaatac gtattaacat
    24181 ttttaatttt atctttacat tgttacttat tgaacaatag gaaattaaag aaacttttga
    24241 aacttatgta aagtgatt
//
LOCUS       DAFLWQ010000039        23938 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.040, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000039 DAFLWQ010000000
VERSION     DAFLWQ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23938
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.040"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            125..2722
                     /gene="adhE"
                     /locus_tag="L1V16_001573"
                     /gene_synonym="adhC"
     CDS             125..2722
                     /gene="adhE"
                     /locus_tag="L1V16_001573"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBN1275916.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            2951..4057
                     /locus_tag="L1V16_001574"
     CDS             2951..4057
                     /locus_tag="L1V16_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBN1275917.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            4074..5102
                     /locus_tag="L1V16_001575"
     CDS             4074..5102
                     /locus_tag="L1V16_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HBN1275918.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLEGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            5108..5587
                     /locus_tag="L1V16_001576"
     CDS             5108..5587
                     /locus_tag="L1V16_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBN1275919.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            5603..6898
                     /locus_tag="L1V16_001577"
     CDS             5603..6898
                     /locus_tag="L1V16_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HBN1275920.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            6909..7733
                     /locus_tag="L1V16_001578"
     CDS             6909..7733
                     /locus_tag="L1V16_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBN1275921.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPETP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            7898..8797
                     /locus_tag="L1V16_001579"
     CDS             7898..8797
                     /locus_tag="L1V16_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1275922.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(8923..9792)
                     /locus_tag="L1V16_001580"
     CDS             complement(8923..9792)
                     /locus_tag="L1V16_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HBN1275923.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            9945..11405
                     /gene="rhaB"
                     /locus_tag="L1V16_001581"
     CDS             9945..11405
                     /gene="rhaB"
                     /locus_tag="L1V16_001581"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HBN1275924.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            11402..12658
                     /gene="rhaA"
                     /locus_tag="L1V16_001582"
     CDS             11402..12658
                     /gene="rhaA"
                     /locus_tag="L1V16_001582"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HBN1275925.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            12672..13517
                     /gene="rhaD"
                     /locus_tag="L1V16_001583"
     CDS             12672..13517
                     /gene="rhaD"
                     /locus_tag="L1V16_001583"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HBN1275926.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            13519..13830
                     /gene="rhaM"
                     /locus_tag="L1V16_001584"
     CDS             13519..13830
                     /gene="rhaM"
                     /locus_tag="L1V16_001584"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HBN1275927.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            13912..15063
                     /gene="fucO"
                     /locus_tag="L1V16_001585"
     CDS             13912..15063
                     /gene="fucO"
                     /locus_tag="L1V16_001585"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HBN1275928.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEVSVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            15190..15948
                     /locus_tag="L1V16_001586"
     CDS             15190..15948
                     /locus_tag="L1V16_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBN1275929.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            16048..16692
                     /locus_tag="L1V16_001587"
     CDS             16048..16692
                     /locus_tag="L1V16_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HBN1275930.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            16699..17706
                     /locus_tag="L1V16_001588"
     CDS             16699..17706
                     /locus_tag="L1V16_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBN1275931.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            17722..18564
                     /gene="kduI"
                     /locus_tag="L1V16_001589"
     CDS             17722..18564
                     /gene="kduI"
                     /locus_tag="L1V16_001589"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HBN1275932.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            18584..19387
                     /locus_tag="L1V16_001590"
     CDS             18584..19387
                     /locus_tag="L1V16_001590"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HBN1275933.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(19636..20700)
                     /locus_tag="L1V16_001591"
     CDS             complement(19636..20700)
                     /locus_tag="L1V16_001591"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBN1275934.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(20697..21782)
                     /locus_tag="L1V16_001592"
     CDS             complement(20697..21782)
                     /locus_tag="L1V16_001592"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HBN1275935.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(21795..22772)
                     /gene="mvaD"
                     /locus_tag="L1V16_001593"
     CDS             complement(21795..22772)
                     /gene="mvaD"
                     /locus_tag="L1V16_001593"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HBN1275936.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(22765..23709)
                     /gene="mvk"
                     /locus_tag="L1V16_001594"
     CDS             complement(22765..23709)
                     /gene="mvk"
                     /locus_tag="L1V16_001594"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HBN1275937.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
BASE COUNT         7545 a         4337 c         5298 g         6758 t
ORIGIN      
        1 aattttatat ttaaaaataa ctgtgaaaaa aatcacaaaa aagtgtttac atagaaaaat
       61 aaatattgta tgatatacat gtgaattatt taacaaataa ccatgaccca ttaggaggat
      121 aatgatggct aaagtaatag aaaaagaaaa aacgaagaca attgacgtac aagcaatgat
      181 tgatgatttg gcagaaaaag caaatgcagc attgaaagaa atggaaagct ttgatcaaga
      241 aaaagtagac catatcgtgc atgaaatggc aatggcagct ttggatcaac atatgccatt
      301 agcgaagatg gctgtagagg aaacaggccg cggtgtttac gaagataaag caatcaaaaa
      361 tatgtatgcg tccgaatata tttggcataa tatcaaacat gataaaacag ttggtgtgat
      421 caatgaagat gtccaaaaag ggttgattga aattgctgaa ccagtcggtg tggtttgcgg
      481 agtaactcca acaacgaatc cgacttccac aacgattttc aaatcaatga tcgcgttgaa
      541 aacaagaaat ccaatcgttt ttgctttcca tccaagtgcc caaaaatctt ctgcagaagc
      601 agcacgagtg gtacgtgatg ctgctatcgc tgccggagct cctgaaaatt gtatccaatg
      661 gatcgaacat ccttcgatcg aagcgacttc tatgctaatg aaccatccag gtatcgcgat
      721 cgtcttagcg acaggtggag ctggaatggt caagtctgct tactctacag gaaaaccagc
      781 tttaggtgta ggtccaggta acgtaccagc ttatattgaa aaaacagcaa aaattaaacg
      841 tgcagtgaac gatttgatcg tttcgaaaac atttgataat ggaatgattt gtgcttctga
      901 acaagctgtg atcgtggata aagaaatcta tgcagcagta aaagcagaat tccaagcaca
      961 ccaagtttat atcgtaaaac cagatgaatt gcaaaaatta gaagatgcag tgatgaacga
     1021 aggaaaatat gcggtcaatc catcaatcgt tggacattct gcgatggaaa tcgcaaaatt
     1081 ggcaggaatc agtgtaccaa aaggaacgaa aatgctgatt gctgaattgg aaggcgtagg
     1141 cccagattat ccgctatcaa gagaaaaact ttctccagtt cttgccatga tcaaagctaa
     1201 caacacggac catgcgtttg atttgtgtga aggtatgttg aatcttggag gattaggaca
     1261 tacagcagtt atccattcag aaaacgaaga gttgcatgtc aaattcggtc ttcgaatgaa
     1321 agcttgtcgt attttagtga atacaccatc tgcagaaggc ggcatcggtg atatctataa
     1381 cgaaatgatt ccgtcattga ctttgggatg cggttcttat ggtaagaact ctgtttctcg
     1441 taacgtctct gctgtaaact taatcaatgt caaaactgta gcgaaacgga gaaataacat
     1501 gcaatggttc aaattaccgc caaaaatctt ctttgaaaag aactctctat tgtacttaga
     1561 gaaaatggaa aacgttgaac gtgtcatgat cgtttgtgac cctggtatgg tccaattcgg
     1621 ttactgcgat acagttcgtg aagtattggc acgacgtaaa aatgatgtga agatcgaagt
     1681 cttctcagat gttgaaccga acccatcgac aaataccgta tacgcaggaa cgaaactgat
     1741 ggcagacttc aagccagata cagtaatcgc tcttggaggc ggttctgcaa tggacgcagc
     1801 taagggaatg tggatgttct atgaacaccc agacacatct ttctttggtg caaaacaaaa
     1861 attcttggat atccgtaaac ggacatataa gatcgacaaa ccagaaaaaa cacaattcgt
     1921 atgtatcccg acaacatcag ggactggttc tgaagtaacg ccatttgcgg tcatcactga
     1981 cagtgaaaca catgtgaaat atccgttagc agattatgca ttgacgccag atgtcgcaat
     2041 cgtcgatcct caattcgtca tgtcagttcc agcatctgtc acagcagata ccgggatgga
     2101 tgtgttaaca catgcaatcg aatcctatgt ttcagtcatg gcttcagatt atacacgtgg
     2161 attgagccta caagcaatca agttagtctt tgactattta gaaaaatcag taaaaacacc
     2221 tgatatggaa tcacgtgaaa aaatgcacaa cgcttctaca atggctggta tggcgtttgc
     2281 taacgcattc ctaggtattt gtcactcagt cgcacataaa atcggcgggg aatacgggat
     2341 ccctcatgga cggacaaatg cgattctttt accgcatatt atccgctata atgcaaaaga
     2401 tccacaaaaa catgcgatgt tccctaaata tgactatttc cgtgcagata cagattacgc
     2461 agatatcgca aaattcttag gtctgaaagg cgaaacaaca gaggaattag tcgaagcttt
     2521 agcaacggct gtttatgaat taggaaaatc tgtcggcatc aacatgagtc taaaagctca
     2581 aggagtcaca caagaaacac tagatacaac cgtagaccgt atggctgaat tagcttacga
     2641 agaccaatgt acgacagcta atccgaaaga accattgatc tctgaattga aacagatcat
     2701 cattgatgct tacaacggat aagcaaaaga aagcgtagaa aaaagataag aaaatagatg
     2761 aaaaagaact tggaaaacgt tgtttctcca agttcttttt ttaatttcca agtaactgaa
     2821 agttactttt gttatttaac atttaggtca attttagaca gtttttgttc aaaaagcgat
     2881 atttatagtg gacggtatta ctgctatatt aaggatataa aatgaaagcg tttaaaaagg
     2941 tggcgtaaag atgattatta aagaagagat ttttgtacct aaagaattag tgaaagaaaa
     3001 aattgacctg ctcgttgaaa acctgacaac gatcaaagac gataatggtg aatttttgtt
     3061 ggactttgat ggactgaaag tagatgacaa aagctggaca gtgtggaatt ggccacaagg
     3121 tgtcggtcta tatggtattt ataaaaatta ccagatgaca aaaaatcctc gcgcttatca
     3181 agtggtcaat gaatggtttg aggatcgtat ggaagaaggc gctccgccca aaaacgtcaa
     3241 tacaatggca ccgctattga ctatggctta cttgtatgaa gacacgaaag attcacgcta
     3301 tttgccttat ttagaacaat gggcagaatg ggtcatgaat gacatgcctc ggacaaatga
     3361 agacgggtta cagcatgcca catatggacc ggaaaataag aatcagttgt gggacgatac
     3421 attgatgatg acagtgcttc ctttggcaaa aatcgggaaa ctgttgaatc gcccagaata
     3481 tttagaagaa gctcgttacc agtttatgat ccatatcaaa tacttgatgg ataaacgaac
     3541 aggattgtgg tatcacggct ggacgtttga aggaaatcat aactatgccg aagcattttg
     3601 ggctcgtgga aactgctggt tgacgattgc tattccagag atcattgaaa tcttagaatt
     3661 atcgaaagaa gatgcattgc gcaaattatt gatcgaaaca cttgaagcac aagtgcgtgc
     3721 attaaaaact tatcagtctg aaagcggttt atggcatacg ttgttggatg atccttcttc
     3781 ttacgtagaa tcttctgcaa ctgcaggatt tgcttacggt attttgaaag cggtccataa
     3841 acgttattta ccacaagaat ataaagaagt cgcttatcgt gctatccaag gattgcttga
     3901 acaaatcgat gaaaaaggag aagttcaaaa cgtttcaatc gggacaggaa tgggggacag
     3961 tttagatttt tatcggaata tcggaatcac agcaatgcct tatggacagt cgttaacggt
     4021 gctttgtttg acagaattgc tcgtctctta ttgttaaaag aaaggaaacc catatgaaaa
     4081 aaacatcact gctgtttgca gcaagttcgc ttagcctagg tctgctaggt ctaagcggct
     4141 gcggaaataa ttctagtgtg gcaactgtcg cagatgcaga tgtaaatgag atagttacct
     4201 tgcgctttgc ttatgcaagc aacagccagc cagtaattga tgcaatgaat gaatttgggc
     4261 gtttagtaaa agaaaaaaca gatggttccg tacagatcca gtatttccca gatggacaac
     4321 tgggtggaga acgtgaactg atcgaattga cacagtcagg agcagtagat ttcacaaaag
     4381 taagtgcctc agcgttggaa agtttctcta aagattattc gattttttca gttccttatc
     4441 tattcaatga tgaagaacat ttctttaagg tgatggataa tgaagaaata atggagccaa
     4501 tctaccaatc gaccaaaaat ttaggattta ccggattgac ctattatgat tctggtcagc
     4561 gcagctttta tatggtagac ggtccgatcc atacgccgga agatttggag ggaaagaaga
     4621 tccgtgtgat gcaaagcgaa accgctatca aaatggtaga gcttttaggc ggttcgcccg
     4681 tacctatggg aagtgatgaa gtgtacacgt ctcttcaatc caatttgatc aacggatcag
     4741 aaaacaatga atttgtcttg tatacagctg gacatggtgg tgtggctaaa tactattcct
     4801 atgatgagca tacacgtgtg ccagatatca tcatcatgaa tgatgccatc aaagaacagc
     4861 taactgatga gcaggaaaaa gccattgaag aagcagcgaa agaatcaacg gtttttgaaa
     4921 ttgaagcttt tgcaaaagca attgaagaag aaaaagcttt agcacaagaa gaacatggag
     4981 tccaattcaa tgatgtagat aatacaccgt ttcgagaggc agttgcccca cttcatgata
     5041 tattcaaaaa cgatcctacc tacaaagacc tttatcaaaa gatccaagag caaggagcgt
     5101 agctgtgatg aaaatgattt taaacaaggt attagagatc ctgggagctg ttttgcttgt
     5161 tgggatggtc gctgttgttt tatggcaagt attttccaga acggttttag gaaatccaaa
     5221 tacggtcacg gaagagcttg ttcgattcgg tcttgtctgg tttgccatgt tgtcttccgc
     5281 gtatgttgtg ggacaaaaag cacatttagc cgtaacggtt ttaagtgaaa aattaactgg
     5341 caaaaaaagt aaaattttag aagttgttgt tcaaagttta tttctggtat ttgctgcgat
     5401 gatcatggtg tatggcggat ggaatgctgt cacattgaca atggggcaga tctcgccttc
     5461 tttaagtatt cctatgggat atgtttatct gtcagtacct gtatcggggg tactcatcat
     5521 tatctatagc ctgatcaatc taatcgatac attaagcaac aagccagcaa ttcaagaaaa
     5581 aatataaaaa tggaggaata aaatggcaat agaagccgga ttagtgttat tttttgtatt
     5641 tgttgtgttg cttgtattag ggatgccgat tgctataagt attgcattct catcgatgat
     5701 gactttattg ttagttatac cgtttgatgt ttctgctttt agttcagctc aaaaaatggt
     5761 gggaagtatc aatagttttt cgctgatcgc tattccgttt ttcgttctct cgggcattat
     5821 catgaataat ggagggatag ctaagaaact agtggatttt gcgatgttgt tcgtcgggcg
     5881 cgtgccgggg gctttggctc atacgaatgt gttagggaat gctttatttg gttccatctc
     5941 tagctcggcc attgccgctt ctaccgcgat tggcggagtg ttgatccctc agcaagtgga
     6001 agaaggatat gaccggaagt ttgcgacagc ggtcaatatc gcgtcagctc cgacaggtat
     6061 ggtcattcct ccaagtactg cttttatcat gtattcactt gttgctggtg gtgcttcgat
     6121 ctctgctttg tttatgggag gttatctcgt aggcgctttg tgggcgctag gaatcatgct
     6181 agtagcattc atcgttgcta aaaagaataa ataccctgtt gtcgaaaaag gacagatggc
     6241 tcatgctgga aaaataataa aagaggcgat tcctagcctt ctattgattg tcatcattat
     6301 cggtggtatc ttgacgggga tatttacagc agtagaagct tcagcgatag ctgtcattta
     6361 ctccctgttg attgctatgt tttactataa aacggtaaaa ctaaaagata tacctaatat
     6421 gttgtttcaa tcagtagcaa tgtcagggac gatcatgttc ttattggcta cttcttccat
     6481 gatgtctttc gccatggcgt ttaccggtat tcctcaggca attagttcgt tgattatggg
     6541 cgtaacggat aataaattta ttattctgtt attagtcaat cttgtgttat tactggtggg
     6601 tatgtttatg gatgtggcgc ctgctatctt gatttttaca ccaatatttt taccaatcgt
     6661 cacaagtgta ggggttgatc ctgtacatta cgggttgttt tcaatcatga atctgtgtgt
     6721 aggctccatc acgccgccag taggtacagg actatatgtc ggtgcaagtg taggaggcgt
     6781 aaaagcagag gcaatgctga aaccgcttct tcctttttat ggggttatct tagtcgtctt
     6841 gtttttgatt acttacttcc cgcaaatcgt catgtggcta cccaatatgc tgagttagga
     6901 gaatagttat gttgaacatt acaattagag gacatgatct ttccgaagtc caaacgatag
     6961 aagatcttgc agaaaaaaca aaagaacaag ggattcatac actgcagctc gccttaggtc
     7021 tttcgtttcc tgaaacacct tctggcgcaa atgagatcaa ttctgggatg ggaaattatg
     7081 tcaaacgagt tttagaaaag caagaagtga ccgtaggaat tttaagttgc tatatcaata
     7141 tgattcatcc agatttaacg atacgacaag agttgctgac aaagttcgag cagtatcttc
     7201 gctatgcttc ttcctttggt gcgtcgatgg ttgcttcgga aactggatgt gttttgccgg
     7261 aaatccaata tacggaagaa aatttcacag atgaagcatt tgctgaagct gtgtccgtta
     7321 tccgtcgctt ggtaaaagct ggagaaaaat accaaatgat ggtggggata gaaccaggtt
     7381 tgaatcatcc ggtgtattct ttagcaaggg tagagcagct gatccaagca gtagattcgg
     7441 actatctagg aatcatttta gatccgacca atttgatcac aagtagtgat tatcaagaac
     7501 aagtccaatt ggtagaagaa gcttttgaac gttttggtga aaagatatgt gcggttcatt
     7561 tgaaagattt tcgtgtcgaa caggaaaaaa tcgtgccggt aaatttggga gacggtgtga
     7621 tcgagtacac aaaaatcaaa gaaatcatca tgaagaatcg tccgtacctg tatgtggttc
     7681 ttgaagaaac aaaagatgat gggattcgtt atggaagaag tcttcttgaa taatgtaaag
     7741 aagacgttgg ttaactaata tttagaatgg agggggcggg gctagaagat gccacgtctc
     7801 ttctttttta taagagtata taaaagcagc tctttttgat tacaaaaaac gtggtataat
     7861 aaaattgtgc ataagtgaac aaaaggaggt gcggcacatg ctccaaaaga aaatcagcgg
     7921 tgaacaagtc aatacgatgg tttctgatca gtatgaaatc tatcatgtca aagatgtcgt
     7981 cagccaaaat aaaacgatct atcatcatca tgatttctat gagatccatg ctacattaaa
     8041 gggagaagcg actttttatt tgaacggacg acaatttacg atcaaagcag gaagtgtgct
     8101 gctcatccat tccaatgatt tgcatcgtat cgtccgccaa tcttcagatg tattcgagcg
     8161 tgtctatatc tttgtcaccc cttcttttct agaaagtcgt tccacgccat ggtctaatct
     8221 atcggcttgt tttcaaccaa tgggagagaa gaggagtcgt gtattgcaaa tagaacagga
     8281 agtattgaag caaaaattat catttatcga ccatcctcct gataaaaaaa tttacggtga
     8341 agacataaaa tatgaacaag ctctggtaga atacttgatt tttctcaatc aagttgtaca
     8401 aaaagaagag agtgcgcaag aacagaatgc tgtagttcct aatgagcgtg tggaacaaat
     8461 gttacaatat atctcaaaaa atttatctca tccgctttct ttagaggaaa tggaaaagca
     8521 gttttttgtc agcaaatacc atatcacacg agaatttaaa aagtacactg gatttacgtt
     8581 tcatcagtat gtaatgaaga aaaagctgat ctatgccaag cacttgttgc gagaataccg
     8641 cagctctagt gctgtatata gtaaaagtgg tttttcttct tatccgcatt ttctgaaagc
     8701 attcaagaga gagttcggca taacgcctaa agaatttttg aaacgtgata cacagaaaca
     8761 gttggttcat tatgaacatt ttgaagatga acaatgagaa tgatcactaa aaaataaccg
     8821 cagtagctgc tgttgtttac atagaagcag aaactgcggt tattttattt ttatctatat
     8881 atttcaaaat attttgaaaa aatgacgtac atattatatg aatcagctga atttacgaaa
     8941 gtctctcggc gatagtcctg tttttgcttt gaacaggcgg ctaaagtaag caaaattctc
     9001 aatccctatt tcttcggaaa tcattcgaac cgtaaattct gtataccgaa gaaggtcttt
     9061 agcgtaagaa agttttttgc tgatcaaata atcgattggt ggagaaccga taaatttgga
     9121 aaaatctttg ctcagctgat atttattcaa taagaattgt tgttctaatt gatcaagtgt
     9181 aatcgtttct ttgaaatgtt cgtctaagta ttgcttcagt ttgtaaacgt aggcgggaat
     9241 atcctcttct tcgaaatcta gctgatactt ttgcaaaatc agttcattca gcaactcgtg
     9301 gatagctaca gaggactgga aatcggtacg ggcattcgtg ccttgttgca tgtggatcaa
     9361 ttctgtgatc aaatggtgga tcttgttttc tgatggatcc cctgttgaat ggaaggtgtt
     9421 atggccgtct tttgtgaact cctgataaaa tgattggacg ttctgaccat tcaaatggat
     9481 ccaatccatt tcccatggtt cttcgctgat cgtttgataa cgctgatatt cttggcagtc
     9541 aataaaaaat aagtctccag cttttagctg ttgctgatta tcattatatg taagcgaacc
     9601 tttgccagac aaagtaaact ttatcaagta agaaggtaaa tgtgctcgtt cagtatagta
     9661 agggattggt gctttgaagt aaccgatttc ttggatataa aaaaataaat tcctgcttct
     9721 ttgtgtaggc gtcaagatca ctctttttga gtcttccgac catgagtggt tggctttttc
     9781 ccagtaatcc atgtaaacac tcccaacttg tcaagataat gcaattatat accaaaatag
     9841 tgtgaagcaa aatataagat tctgtattat gatagcattg ttaataaatg ataacgcttt
     9901 attaataaag tgctaatcaa caataaagta aaagaggtgg agaaatgaat ccaacatttg
     9961 ttgccatcga tatcggtgca tcaagcggac gactaatgaa aagtacgagg gatgcaaaag
    10021 gttctttgat cttggaagaa gtacaccggt tcaaaaacgg ctttcggaac aaagacggtc
    10081 acgatcgctg gaagatcgat tatcttatca aagagatttt gattggattt gaaaaattaa
    10141 agcagacagg gattgatcgc ctttttgcgg ggatcgatac atgggcagtc gattactgtc
    10201 tgattgatga acaaggggat cggataaatg atccgattgc ttatcgggac aagcgtacca
    10261 atggagcagt agaacagttt tctgaaatct attctctaga taagttgtat gagcagacag
    10321 ggattcagat ccagcctttc aataccttgt tccaattgtt tgctgaagaa aaagaaaatt
    10381 tggcaaaagc acataaattg ttactgatac ctgattattt agggtatgtc tttactggta
    10441 acatggtgac ggagaaaact aatgcatcta ctatgcagct gctgaatgca gggacaaaag
    10501 aatgggaaat agaacttctt gaaaaaatcg gtgtctcgaa ggaattattt ccaccattga
    10561 cagagccggg aacgatacta ggagatctgc aaaaagaaca attttcaaaa tatgatttgc
    10621 cagatgtgac ctttatcaca gtagcaagtc atgatacggc gtcagctgta ttaggaacgc
    10681 caggtcaagg agaacgttgg ggttatatca gcagtgggac atggtcgctt ttagggattg
    10741 aaacaaagat cgccaatgtt tctcgcaatg ctttttctga aaattatacg aatgaatggg
    10801 gtgcccataa cacggtgcgt tttttgaaaa acatcatggg gatgtggttg atccaggaag
    10861 ttgcccgaat gcaagagtac gagtacagtt atgcggaatt ggcagagctt gctgcaaaag
    10921 aaaaaccgct gcagcaagtg atggaaatca atgaccctcg atttttgaat cccccaaata
    10981 tgatagaaga gattcagcaa tactgttttg aaacagagca gccagtccct gtctcatcgg
    11041 gagctatcgc tcgttgtgtg tatgataatc ttgctctttg ttacgcacaa gagctgatca
    11101 aagtagaaca cttaactgga acgaaattgg aaaagctgca catcgtaggg ggcggatcga
    11161 ataatcgtct actgaatcaa ttgacagcag attatgccgg aatcattgta gaagcaggac
    11221 ctagtgaagc cacagcaatc gggaatgttg ccatgcaaat gctcagtaca ggtcagtttt
    11281 cgaatataga acaagcaaga aatgtaatca aacagtcgtt tccatgtgaa actttttacc
    11341 cagatgaaaa taagcaaaac acgatggaat ggtacgtgaa taaaatcaaa ggagtaatcg
    11401 tatgaacacg attgaaagaa attacgaaca agcaaaagaa aaatatgcaa ctatcggtgt
    11461 agatacagat gctgtactag aaaagataca ggacatcaaa atttctatgc attgctggca
    11521 aggagatgat gtcaaaggtt tcttgacacc ggatggcgaa ttgaccggtg gaatcatggc
    11581 gacagggaat tttccaggag ccgcacgaac acctgaagag cttagacaag atctggagaa
    11641 ggcttattcg ttgataccgg gcaaacacaa attgaacctt catgctatct atttggatac
    11701 agaagaatct gtcgatctaa atgaaattga gccgaaacat tttgaaaaat gggtagagtg
    11761 ggcaaaaaaa gaagaaatcg gtcttgactt caatccgact ttcttttcgc atccaatgat
    11821 gaaagacggc tttacattgg ctcatccaga taaagaagtt cgtgaatact ggatcgaaca
    11881 cgggaaaaga agccgcaaaa tcgcggagta ctttgggaaa gaaactgggc aaacaagtat
    11941 caataacttt tgggtacctg atgggatgaa agataatccg attgatcgtt ttaccccacg
    12001 ggaacgttta atggaatcac tcgatgaaat ttttacagaa gagttagatg aacggtatgt
    12061 acaagatgca gtagaaagca aactatttgg tttaggcgct gaagcttata cagtcggttc
    12121 ccatgaattt tatatgggtt acgggttgac tcgtgacaaa cttgtttgtc tagatgctgg
    12181 acattttcat ccaacagaag tgatttccaa taaattatct tcattagctt tattcagcaa
    12241 aggaatcatg ttgcatgttt cccgtccagt gcgttgggat tcagaccatg tggttttgat
    12301 ggatgatgaa ttgcaggaaa tcgctaaaga attagtccgt aacgaattgt tggaaaaaac
    12361 aaatatcggt ctggatttct ttgatgcaac gatcaaccgt atcgctgctt gggtcatcgg
    12421 tacgagaaat acacaaaaag cactgctgaa agctatgctg gaaccagttg agcgattgaa
    12481 agaaatggag ctggcttttg actttacttc aagaatggct tatacggaag aattgaaaga
    12541 tttcccgtat gccgatgtat ggaattattt ctgttacaaa aatcaagttc cagttggttt
    12601 ggattggctg gaagaagtcc aggaatatca aaaagacgtg ttggaattaa gaaaatagga
    12661 gtgtggctat attgaaaaaa atagatattt tacaagcgcc ttatgtgaaa gaaatgatcg
    12721 aaacgacgtc gaatctttat cgcttgggat gggatgaaag aaatggcggg aatatttctt
    12781 atttactaaa agaagaagag atcacaccgt tcttggatcc tgaaaaagtg atccgccgca
    12841 tctcgatgat ttttgatgcc agccgtttag caggatgcta ttttattgta actggttcag
    12901 gaagatattt taaaaatgta gcgagcgaac ctgccgagaa tcttggaatc gttcgagttg
    12961 ctgaagatgg caaaacactg gaacttttgt gggggctgga aaacgaatgc cttcctacaa
    13021 gcgagttgcc aagtcatttc atgagtcata tcgcccgttt agaagtagac ccagataatc
    13081 ggatcgttat gcattgccat gctagtcatc tattagcgat gagttttacg catgaattag
    13141 acgaacgttc ctttagtcgt acgctatggc aaatgtgtac ggaatgctta gttgtttttc
    13201 cagaaggaat ttccatcatt ccgtggatgg ttccgggaac aaatgagatt ggggaagcaa
    13261 cagctgaaaa aatgaaagaa actcgattgg ttttatggcc acaacatgga atctacgggt
    13321 caggaaaaga catggatgaa gtctttggtt tgatcgagac agcagaaaag gcagcagaag
    13381 tctatacgta cgtcaaagcg caaggaccaa tcttgcaaac aatcacggac gaaaacctgt
    13441 ggcatttagc agatgcgttt ggtgtcactc caaaagcagg ttatttggag gaagttcata
    13501 cgaaagcagg tgtctgacat ggtgaaaaaa gctttttgca tgaaagttta cccagaaaaa
    13561 caagaagaat acaaaaaaag acatgatgaa ctttggccag aaatgcgtac agcacttcgt
    13621 gaacacgggg tcatcgacta ttcgatctat cttgatccga gtacaagttt gttatttggt
    13681 tacttagtga tcgaagatga aaagttatgg gaaaaaatgg caaatacatc tatcaatcaa
    13741 aaatggtgga agtacatgga agatatcatg gagacaaatc cagatgcctc tccagtcagt
    13801 tgggaattga tgccagtctt tgaactgtag caacaagcaa ctgggcaacc ggttgcttgg
    13861 ggttctttcg tttttattgt gaaaaaaaat acaaattagg aggaatagaa aatgagtaat
    13921 cgaatgattt taaatgaaac atcgtatttt ggaaaaggag cgattgagtc gatcgtccct
    13981 gaatttcagc agcgaggatt cggcaaagca gctgtcatta ctgacaaagg attgatcgag
    14041 cacggtatag caacaaaagt aacagaactt ctagataaag cagcaatcgc ttatgcttta
    14101 tacgacggga tcgtacctaa tccaacgatc caaaatgtaa aagatggagt ggcttttgtt
    14161 aaagaggcag aggcagactg tttgatcgca atcggtggag gttcgccaat cgatacggca
    14221 aaagccattg ggattatttt gacgaatcca gagttttcag acgtcattag tttagaaggt
    14281 gttgctgata cgaaaaatcc atgtttacct atattagcta taccaacgac ttctggaaca
    14341 gcagcagaag taacgatcaa ctacgtcatc acagatgaag taaatcaccg aaaatttgtt
    14401 tgtgttgatc ctcatgatat cccaatcgtc gcgttcatcg acagcgatat gatgatggga
    14461 atgccgaaaa aattggctgc atcaacaggt atggatgcta tgacgcatgc tattgaaggg
    14521 tttatcacaa aaggcgcttg ggaaatgact gatatgctgc atttaaaagc aatcgaaatc
    14581 atcggccatt ctttggaagt ttctgtagat ggcgatcaaa atgggcgaga aaaaatggca
    14641 ttaggacagt atattgcggg aatgggcttc tcaaatgtcg gtttaggact ggtacacggg
    14701 atggctcacc cgttaagtgc atggtacaac attcctcatg gcgtagcgtg tgcagcactt
    14761 ttgccaactg tcatgaaata taacaaagaa tatactggag aaaagtaccg tgagatcgct
    14821 cttgttctag ggattaaagg agcagctgaa atgtctttag aagatgtaag agaagcggct
    14881 tgtggtgaga tcgatcggtt gagcaaagcg gttggaatcc cagaaaccat ttctgaatta
    14941 ggtgtaaaag aagcagatat tccagcaatt gcagaagatg ctttgcgaga tgtatgcaca
    15001 ccaggaaatc caagagaaac gacagtagaa gaaatcattg ctttatatca aagtttgatg
    15061 taaaaacgaa gcggatcttc aacattaaat tgcctgtaaa gagaaatggt agtttatatc
    15121 tggatatctc ttttaaattg atggtatttc cgctataatt tttcttataa agaaatagga
    15181 gaatattata tggaaaataa aaagccttat ggaactgtat tgatcaaagc ctctaaaata
    15241 ctagactatt tagcggaaaa ccaagatgtc tctttgcaga cgatcgcaaa gggtgtggga
    15301 atgacctctt ctacagtctt gaaaatacta gatactttgt tgatgatcgg ctacgtaaat
    15361 aaaaattcag agaaaaacta tcgtttaggt gcaaagctta ttcgctacgc gaataaaaac
    15421 attgaacaaa tcgatttggt agagttgact ttaccgtttt tagaacagct gcagcaaaag
    15481 atcgatgaga ctatccactt aggggtattg gacaacaatg agatcttgta cgtgaacaaa
    15541 ctagatccaa aacatcaaac gatccgcatg tcttcaaaaa tcggaatcac ccgaccatta
    15601 tacaattctg cgatgggcaa agccgtatta gcagaattca gtgaagagca gtacactgat
    15661 tatcttgaaa agcatccgtt gatcccttac acagaatata cgatcaccaa tgcattacgg
    15721 ttgaaaaagg aaatccaaac ggtaaaagaa acccacatcg catttgacga tgaagaaatc
    15781 gaacgtgata ttttttgtat aggagcctca atcgtgaaaa acgaacaaat cattggtgca
    15841 tttagtgtaa gtatgccgaa atatcgttta acagatgaga caaaagaaca aataatcagt
    15901 gccctcaagc aaacaaaaag cgaaatcgag caaagaattc aaaaataatg aaaaaagcgt
    15961 ttgcaatttt tcttttctgc cgtataatat gggtatagat ttccaagtta taaaataaaa
    16021 tttctaaata ggaaataggt ggagaagatg aaaaaaattg atattttatc tcgattgaaa
    16081 aacgccggag tgattgcggt ggtacgcgga aaaagcaaag aagaagcttt gaatgcttgc
    16141 cacgcaatca tcaaaggtgg tctaactggt attgagttga cttttacagt ccctcaagca
    16201 gatcaagtaa tcaaagaact tttgtcattc tacaaagacc aaccagaaat agtgattggc
    16261 gcaggcacag tattagacgc tgtcacagct cgcttggcta tcttagctgg cgcagagtat
    16321 attgttagcc cttcctttga tcaagaaacg gcagagatgt gcaatctgta tcaaattcct
    16381 tacttaccag gatgtatgac tattaccgag atcaaaacag cgctgaaaag cggggtagat
    16441 atcgtcaaac tatttcctgg aagcgcttat ggaccaagta tcatttctgc cttcaaggcg
    16501 ccgatgcctc aagtcaatat catgccaact ggcggtgtga gtctggacaa tatgaaagag
    16561 tggttcgatg ctggtgtcgt aacagtcgga gtaggtggga accttttagc acccgcagct
    16621 acaggagatt ttgacaaagt aacggaagtc gcgcaacagt atgcagcaaa aatgaaagaa
    16681 atcaagaggt agctgcttat gggaaaagta gtgacactcg gagaaatcat gttgcgattg
    16741 tccacagagc agggaacccg tatcgattca agtgaacgat tcgctgccca ttatggcgga
    16801 ggggaagcaa acgtagcaat ttctttagct aattacggac atgaagcgat ttttgctaca
    16861 aaagtacctg ataacgcatt gggaaaagca gtcaaaaagc acttgcaatg ttatggagta
    16921 gatacgaaac aggtattatc tggtggatca agactaggta cttattatat ggaaactggt
    16981 agtggcgaac gcgccgcctc agtgatctat gatcgtgccg gatcaagttt tgctgaaatg
    17041 gatcatttgg aatggtcgct agaggagtta ttccaaggaa tagatatatt tcatgtttca
    17101 ggaatcaccc cagctttgtc taaaaaatgg caaaaaatga cgaaacaggt gatagaagct
    17161 gcaaaaaaag ctggctgcct gatcagcttc gatatcaact atcgtggaaa attatggaca
    17221 cagcaagaag ccagcgaagt aatccatcag cttttacctt tagtagatat ctgctcagct
    17281 ggaaaaatgg atgctcttta tttgttaggt atcgagaaag cgccagaagc agaagaacaa
    17341 cctctaattt attattatca aaaaatgcag gaaaagttcc cgaatattca ggtgttttat
    17401 tcgaccaagc gtaccgttca ttcagcaagt gaaaatgaat tgaaggggac attgtggatg
    17461 aaccatgaat atgtggaatc ccaagtccat agaatcaccc caatcgtgga tcgagtaggt
    17521 ggcggagatg cttttgcagg tggcgtgctc catgggattt tatccaatat gtctccgcaa
    17581 gaaatcattg attttgctac ggcagcttct gccttgaagc atacgatcca tggggactgc
    17641 aaccaattta gtcaagaaga agtcgcacaa tttttagcat gcggctctgg aaaaatcatt
    17701 cgatagaagg agtagaagaa aatgcaagaa atggaaacac gttatacaca cagtccagaa
    17761 gatatccgtc attattcaac ggaacaattg agaaaagaat ttttagtaga aaaggtattt
    17821 gaaccaggga aaatcagttt gacttatacg cacaacgatc gaatgatctt tggtggagtg
    17881 acacctactg aaaaagaatt agaaatcaca ttagacaaag aactaggtgt tgattacttc
    17941 ttagagcgtc gtgaactagg tgtgatcaat atcggtggac caggattcat cgagatcgat
    18001 gggcaaaaag aagaaatgaa aaaacaagac ggatactata tcggaaaaga aacacgacat
    18061 gttgtatttt cttctcaaga tgctgaaaac ccagctaaat tctatattag ttctgttcca
    18121 gctcatcata aatatccaaa tgtaaaaatc agtatcgacc aagtaaaacc aatggagact
    18181 ggtgaaggcc tgacactgaa tgaacgtaaa atctaccaat acatccatcc aaatgtatgc
    18241 gaaagctgtc aattacaaat gggttatacg attttagaac caggaagcgc ttggaatacg
    18301 atgccttgtc atacacatga acgtcgtatg gaagcttatg tctactttga ttatgccaat
    18361 gaagatacac gtgtgttcca catgatgggc aaaccagatg aaacaaaaca tttagttgta
    18421 gacaatgaac aagccattat ttcgccaagc tggtcgatcc attcaggtgt aggtacaagc
    18481 aattactcat tcatctgggc aatgtgcgga gaaaatatca cctatacaga catggatatg
    18541 gtgcaaatgg atcaattaaa ataagcataa gggagagaaa atgatggaat ttagtatgga
    18601 tatgtttcgt ttagatggaa aagtagcatt agtcaccggt gctgtctatg gtattggatt
    18661 tgagattgca cgctctttag ctacagcagg agcaaaaatc gtatttaata acttgaatca
    18721 agaatcagtt gatgaaggta tagcgcatta taaagaagca ggcatcgatg caaaaggtta
    18781 tgtctgcgat gtgaccgatg aagaagcggt tcaagcgatg gttcaacaga tcaaagaaga
    18841 tgtaggttca gttgatattc tagtcaacaa tgcagggatc atcaaacgga caccgatgat
    18901 cgaaatggat gcggcagact tccgccaagt aatcgacgtg gatttaaatg ccccattcat
    18961 cgtttcaaaa gcagttattc cggatatgat cgaaaaaggc ggcggtaaaa tcatcaatat
    19021 ctgctccatg atgagtgaat taggacgcga aacggtcagt gcttatgctg cggcaaaagg
    19081 cggattaaaa atgctgacga aaaacatcgc ttctgaatac ggtcaataca atatccaatg
    19141 taatggaatt ggaccaggtt atattgctac accgcaaact gctccattac gcgaaacaca
    19201 agaaaacggt gaacgtcatc cattcgatca atttatcgtt ggacgtacgc cagcagcacg
    19261 ctggggcgag ccaatcgatt tggctggacc atctgtcttc ttggcttcta gcgcatctga
    19321 tttcgttaac ggccatgtct tgtatgtgga cggaggcata cttgcctata tcggaaaaca
    19381 accttaaaag agctttagta cactgtttag tggagaggtt gtgaaatcag cggattgaac
    19441 gaataccgaa ggacagctga ttaaacatca tttattcgaa aaaagaggct gggacagaag
    19501 catttaactc caagaaataa gaaggaattc acgaaaattg cttttcaaat ttttgtgaat
    19561 ttcagcttat ttccgaagga gttgctttta cttccgccgt ttgtacgtgt ttagagcgtg
    19621 agacaaaagt gttctttact tttgtcccac gctcttttct gtgcgtcttc catacttcac
    19681 taagtcgatc cctcttgctt cgcaccaatc cttcactggt ccggaaaaga tcagagattg
    19741 ttggtgtagg gccgcggtat tcgttgcgcc gaccatagta taaagcagac gaagctcttc
    19801 ttgccattgc ttcatcagta taatagtttc ttctacgccg tgattcatca gatgcgtcag
    19861 tacggttcct gaagtaccca cggcatttgc gccgagacaa agggctttaa atatgtcata
    19921 ggcattgcgg atacctccgg aggctaggat ttccatagaa gtgtctgctt catttgcttc
    19981 aagcaatgaa gagactgtcg attgccccca gtcagctaaa taactcagtt cccgcttgga
    20041 gcgacgggcg ttttcgatct gggtgaagct tgttccgctt cgaccgctga tatcaactgt
    20101 atgaactcct aaagcagcta gatcattgag cgtttctctt gtcatgccaa aaccgacttc
    20161 ttttacgatg agggggacgt caatggctgt ttgagtttct tgaataagta ctttccaatt
    20221 ggtaaaatca cggtctccct caggcataac caactcttga ggtgcattca aatgaatctg
    20281 taaggcatct gcgtgaaaca atcggatagc ttctttggct ctttcgacag aagtccctgc
    20341 accgatgttg gcaatgattt tcccgtgagg atattcttgt cgcataatcg tataagtatc
    20401 ggctaaagaa gggactttca aggcagcgct gactgaacca gtggcaatca tcaaatctgc
    20461 ttctcttgcg acgattgcaa gatcttggtt gatttttttt gttttttcgc ttccgccagt
    20521 catcgcattg atataaaatg ggctgcttag tgtaaaccca actgcctgtg tacttagatc
    20581 gacatcagaa actgctattt gcggcaaagg gttatggatg atccgtacga agtcaaattc
    20641 gtttttttgt ttatcatgaa aggctttagc tagtgaaaca tgttcgtctt ttcgattcat
    20701 cggttttcct ttctttgatc gctatagaca tgtaacggca gtggagtgat ttctgctttt
    20761 tcccatgcac tcattaaagg aagaatgcca gatttctggt caacaattac gattccgcaa
    20821 tcgcccccac ctgcaccaga agattttgcg gctccttcat actgttcagc taaattacac
    20881 aatttgttca aagcaggcgt ttcgatgacg accccagtga ttgcagataa atcatgcagt
    20941 aattgtcggt tttttcgaat catctgttgg atcaacgtta cattattttc tttaaaccct
    21001 ttgatcattt cgttgacaca ttctgtacta ttttttaaga aaagctgata agccaccatt
    21061 ttatcttctc tcgaacggtg aacttgatcg accaaatcag aagtagaggc agggctaccc
    21121 gtccaaccaa tcaataaacg taaatcttca ggagcaatca atggctcaat ggatagacct
    21181 ggccaatcca gggcaagtaa ctcactgata gaatgctgag tttcttgttc ttggagccaa
    21241 ggatggtcga aggttgagaa agcgatccag ccaccataac agctagcagc gatgtcgccg
    21301 caggaaccat tatcttgaac tgctaaattg gctagtgctg caatcttgaa aatctccaac
    21361 tgagataaat tcaacgcgta aaaaacattc aaggctttga ccgttgcaac ggtcacggca
    21421 ccgctagaac ccaatccata tttccggcca tttgaactgt ctaactcact tgttactttc
    21481 agatcataaa aggataaaag aatgtttttt tcttgtgcat acttttcagt caagcgaata
    21541 gcagcaagga tataatgaaa aggattttcc cgaatatcta aaactaattc tccgttgcgt
    21601 cttgtccaac gtacaggcat cccactatat tgtgcagatt ggatacttcc gacttttcgt
    21661 gcagattcta cagtgactgt cacgaattga tcgactgcag cgataactgc tggatggcct
    21721 gtttcaacaa ctgcatattc tccggcaata tagagtttgc ctggtgcaga tacttcaatc
    21781 ataaaaatct ccctttattc aataatcgca attcctggac cagcatgtgc agtaattact
    21841 tgttctttgc taaataattt ggtaaatgtt tcttgtacct cagataaatg gctgttttcc
    21901 actaaaactt tgacattagg gccagcatcc atcgtaaagt agcatggaat gccttgcttt
    21961 ctcaattgtc gcaccgcatc catcgctttt aagctgtcag gagaccagta agtgaatgga
    22021 ggctgggcag ctaaagtcgt tccatgcatt tttagtccgt ttctttccat cgtttctccg
    22081 agaagttgga aatcttttgt tttgattgct tgtttcaatt gatatagatc cccttcaacg
    22141 gaatctaacc agccttgata aaaactggat gtttcgactg tccgacgcat cccatttctg
    22201 ctggacactt cttttttctg gtcgttgatc aaaacgaaaa ccattgctaa atcgtcttcg
    22261 aaagaatcgg aagggactgg cttagcgtaa gaacttaagt cgtcatggcc tttttcccat
    22321 tcgacgaaac caccgaaaat acttcggcaa gctgaaccag acccgcgtcg agcaaatctt
    22381 gaaagagaga gatcatctaa tccaagctta agagcagtat tgcaagcgcc tgctaaagca
    22441 gctagcccgc tggcagagga ggctaatcca gctgcggtag gaacgaaatt ctgactgatt
    22501 actgaagctt ttagtgagag gccggcttct ttacgaaaaa ggtcaagaaa ctgactgact
    22561 ttttttgttg ctttttcgtc ttgcaaggtg ccatctagat aaaattcatc taccatatag
    22621 ctatcagaaa agatgacttc tgtctctgta taaaatgcat ccaatgttaa cgaaaggctg
    22681 ttgttcattg gaaggatgag ttcttcattt ttcttacccc aatatttgat tagagcaatg
    22741 ttggtatatg cgcgtgcttt gcctttaaac ataggtatgt actcctaatc cttgtatcca
    22801 agtttcagca gcacccgcat cttcaagtgc ttgactgatt tcttgggctt ttgtttttgt
    22861 ttgtgctaat gcaatcatac agccaccgcg tccaccgcca gttaatttgg cacccaatgc
    22921 cccggtatct tttgctgttt ggatcaatag attaagaaaa tcattgctga ttgtcagctt
    22981 ttccagaagt gattgtgatt catccattgt ctgtgccaac gtttctggtg aattttcaat
    23041 gattgcttgt tttgcttgct tcgtcaagta tcctaatttt tggatcattt gtccagtttc
    23101 atgaggctgg gtttcaaaga ggtgagcgac atctttgacg gcttctcttg tttgtccttt
    23161 gattcctgta tcagcgacaa tcaaaaaagc atcgatgttc aaagaaaagt agtcgaaagg
    23221 atgccctttt gtaaaataaa tcggctgcaa gctgctagta gcggctgcat cgattccact
    23281 aggattaccg tgggcgattt tttccgaaag ctggacattt tctaatagta tttcacgaga
    23341 caaaggaaat gctaagtaat cataaaaagc acgagtgact gctgtggcga ctgcagcgct
    23401 tgatcccatt ccacgttcag caggaatcgt gctttcaatg gtcagttgca agtttttttg
    23461 gatgtcatgc tgttttttta agtgaatgaa taattttttg atatttttta atgcatgagg
    23521 agcttcggct aaatttcctg aatagtagga agaaaccagt tgatcgtcca ttgcatccag
    23581 ctcttcaagg aatgcggtga cttttgttgc atagaaagga aaggcaatcg ctggttctcc
    23641 ataaacaacc gcgtgctcgc ccatcaatat gatctttccg cttgattctc cttggccata
    23701 gtttgccata atctaactcc ttctcacgta aaagtgattt ttaagcaaaa aataaagcgc
    23761 ccaaaacgag ttgcgctgct tcacgaattt ttttgtccac taagggtctc aaaaaacatt
    23821 cctcctttat tttactaaaa ccatctcaga agtaaaacta agaatacgtt ttctaaagaa
    23881 aaaacacttt tttcttaaga attttttgac tttttttctt ctttgactag aaaaaaat
//
LOCUS       DAFLWQ010000040        23828 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.041, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000040 DAFLWQ010000000
VERSION     DAFLWQ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23828
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.041"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(54..788)
                     /locus_tag="L1V16_001595"
     CDS             complement(54..788)
                     /locus_tag="L1V16_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBN1275938.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1120..1524
                     /locus_tag="L1V16_001596"
     CDS             1120..1524
                     /locus_tag="L1V16_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBN1275939.1"
                     /translation="MFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEMHL
                     VDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVAAG
                     KTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="L1V16_001597"
     CDS             1517..2218
                     /locus_tag="L1V16_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBN1275940.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="L1V16_001598"
     CDS             2218..3804
                     /locus_tag="L1V16_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1275941.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="L1V16_001599"
     CDS             3823..4044
                     /locus_tag="L1V16_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HBN1275942.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="L1V16_001600"
     CDS             4041..4802
                     /locus_tag="L1V16_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HBN1275943.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="L1V16_001601"
     CDS             5182..5691
                     /locus_tag="L1V16_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBN1275944.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="L1V16_001602"
     CDS             complement(5766..6305)
                     /locus_tag="L1V16_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBN1275945.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="L1V16_001603"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="L1V16_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBN1275946.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="L1V16_001604"
     CDS             7318..8169
                     /locus_tag="L1V16_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBN1275947.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="L1V16_001605"
     CDS             8197..8832
                     /locus_tag="L1V16_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBN1275948.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="L1V16_001606"
     CDS             8852..9625
                     /locus_tag="L1V16_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1275949.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="L1V16_001607"
     CDS             10033..10830
                     /locus_tag="L1V16_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HBN1275950.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="L1V16_001608"
     CDS             10808..11221
                     /locus_tag="L1V16_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBN1275951.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="L1V16_001609"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="L1V16_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBN1275952.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="L1V16_001610"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="L1V16_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBN1275953.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /gene="maf"
                     /locus_tag="L1V16_001611"
     CDS             15998..16558
                     /gene="maf"
                     /locus_tag="L1V16_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBN1275954.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="L1V16_001612"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="L1V16_001612"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HBN1275955.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="L1V16_001613"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="L1V16_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HBN1275956.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="L1V16_001614"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="L1V16_001614"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBN1275957.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="L1V16_001615"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="L1V16_001615"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBN1275958.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="L1V16_001616"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="L1V16_001616"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBN1275959.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="L1V16_001617"
     CDS             21905..22483
                     /locus_tag="L1V16_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1275960.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="L1V16_001618"
     CDS             22535..23017
                     /locus_tag="L1V16_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HBN1275961.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="L1V16_001619"
     CDS             23134..23508
                     /locus_tag="L1V16_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275962.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7781 a         4286 c         5115 g         6646 t
ORIGIN      
        1 taaaaaaact tggtacgcaa tcgctgtacc aagttttttt atttagcttt tgattaagcc
       61 ataaataata atttatataa gaatactgct acgacaccag cacagatagg tgctacaact
      121 ggtacccatg catatcccca ttgagaagaa cctttatgtt tcaatggaag aagtgcgtgt
      181 acaagacgtg gagcaaagtc gcgggctggg tttagtccag gacctgtagg accaccaagt
      241 gaagcaacta atgtccatac aaggaaacca agtgctaagt gagctgtacc aagattatct
      301 tggaagaatg gtgcttttgt aatacctagg gcaccaaaga ataaaacgaa tgaaccaaag
      361 aattcattga cgaaaccatt gaatttagaa ccaacgctgt tgattgttga gaatgtacct
      421 aacacatggt ttacgtcttc tgtttggtcg tagtaaggtt tgtaacaagc tactacgatc
      481 aattgtccaa tcgctgcacc aatcaattgt gcaatgatat aaggaacaac ttcagcccaa
      541 gggaatagac cattagatgc taaagcaatt gtaaatgctg ggttgatgtg gttaccgctg
      601 attccaccaa aaatcattgc tggcatcata accccgaatc catacccgac agcaatcagc
      661 atccagtcac tgccatatcc ttttgtacct tttaaatcta cgtttgctac agcaccgtta
      721 cctagaacga ttagtaatgc tgtaccaatc atttccgccg caagacgggt cattagtgag
      781 taatccataa atacctccaa aagttataaa aatgcaaaaa aaaaagaaac atcaacacga
      841 aaagcatcgg tgcagtgttt cgtgtcggaa ggatttctgc agtcttaaca aatgtgaata
      901 aaaaaatgaa ttccattact tataagaaac cagaccaaca gtaaaactcc aactcttttt
      961 aaaagttctc cacaaatcac caagcttaac tataaatata ccaaaaaaaa aacgtttttt
     1021 ttctcaaaaa ttgtatctta gaaacagcat gttttgaaac tttcagaaaa ggtttgttag
     1081 taaaatgaaa gctatacgta aggagtgttg tttgatgaaa tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaca
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcaccgggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaacaa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagttt
//
LOCUS       DAFLWQ010000041        23170 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.042, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000041 DAFLWQ010000000
VERSION     DAFLWQ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23170
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.042"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..872)
                     /locus_tag="L1V16_001620"
     CDS             complement(<1..872)
                     /locus_tag="L1V16_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275963.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPL"
     gene            complement(896..1867)
                     /locus_tag="L1V16_001621"
     CDS             complement(896..1867)
                     /locus_tag="L1V16_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBN1275964.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            2573..3952
                     /gene="brnQ"
                     /locus_tag="L1V16_001622"
     CDS             2573..3952
                     /gene="brnQ"
                     /locus_tag="L1V16_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBN1275965.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            complement(4108..4554)
                     /locus_tag="L1V16_001623"
     CDS             complement(4108..4554)
                     /locus_tag="L1V16_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBN1275966.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(4581..4757)
                     /locus_tag="L1V16_001624"
     CDS             complement(4581..4757)
                     /locus_tag="L1V16_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBN1275967.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(4919..5347)
                     /locus_tag="L1V16_001625"
     CDS             complement(4919..5347)
                     /locus_tag="L1V16_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBN1275968.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            5439..6299
                     /locus_tag="L1V16_001626"
     CDS             5439..6299
                     /locus_tag="L1V16_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBN1275969.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPSVEFNLFRRT
                     FVTDEKTLMQALQDALEEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            complement(6383..6733)
                     /locus_tag="L1V16_001627"
     CDS             complement(6383..6733)
                     /locus_tag="L1V16_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBN1275970.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAIIQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(6749..8476)
                     /locus_tag="L1V16_001628"
     CDS             complement(6749..8476)
                     /locus_tag="L1V16_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBN1275971.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     TIIQKMTEE"
     gene            complement(8689..9615)
                     /gene="trxB"
                     /locus_tag="L1V16_001629"
     CDS             complement(8689..9615)
                     /gene="trxB"
                     /locus_tag="L1V16_001629"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBN1275972.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(9760..11196)
                     /locus_tag="L1V16_001630"
     CDS             complement(9760..11196)
                     /locus_tag="L1V16_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBN1275973.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     EKEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(11193..12596)
                     /locus_tag="L1V16_001631"
     CDS             complement(11193..12596)
                     /locus_tag="L1V16_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBN1275974.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMNELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            12826..13728
                     /locus_tag="L1V16_001632"
     CDS             12826..13728
                     /locus_tag="L1V16_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1275975.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            complement(13769..15655)
                     /locus_tag="L1V16_001633"
     CDS             complement(13769..15655)
                     /locus_tag="L1V16_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1275976.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGVVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNPGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(15752..16603)
                     /locus_tag="L1V16_001634"
     CDS             complement(15752..16603)
                     /locus_tag="L1V16_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1275977.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELYQVIQKKYKDTFGCVEKIADFLAEIFNYQMSTDEKMYLTIHIARL
                     VHENRCK"
     gene            complement(17061..18845)
                     /locus_tag="L1V16_001635"
     CDS             complement(17061..18845)
                     /locus_tag="L1V16_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1275978.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPTITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLTKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            complement(18845..20596)
                     /locus_tag="L1V16_001636"
     CDS             complement(18845..20596)
                     /locus_tag="L1V16_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1275979.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLAPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAALLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGCSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQKLEAKIEGGEA"
     gene            complement(20738..20962)
                     /locus_tag="L1V16_001637"
     CDS             complement(20738..20962)
                     /locus_tag="L1V16_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HBN1275980.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            21213..22799
                     /locus_tag="L1V16_001638"
     CDS             21213..22799
                     /locus_tag="L1V16_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBN1275981.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
BASE COUNT         6508 a         4977 c         4115 g         7570 t
ORIGIN      
        1 agtgggaaaa tcgaagtcgt ttgattcgtc aatcctagta attccaattt tttcatcgct
       61 gaagcatcaa tttgatttcc ttcgcgaaca atgatttctc cttggaagat catcactggt
      121 tgtacagctt ctcgtgcaga ttgttttaat tcttctgtct ttttctcatt caatacatca
      181 ttgactacaa tgccttgatc cactaagtag cgaatcattt gttgctgctc tgttgtgaca
      241 ttcaaatact gaatctgatc ttctgcttct tgtttaaaag cttccaattc gctttcacga
      301 acttgtttac tcatctgttc gtcaatgagc ttcaaacttt catccctaac cgtgtgaatt
      361 tccgtttcag tcatttcaaa tatcgtcgaa taaaaattgt tcggcagttt ttggtaaaac
      421 gcaacgtttt ctgcattcac gttttcaaaa tttttcttca gtgtagcaat ccgctcttct
      481 gtagtaggtt tcgggatatt ttcatcttcc ttcgccttat ctaccttgtc attataagat
      541 ttgttgatgg tatcattcgt cttatcgatc aattcgaata attgcttgat ccgattgttc
      601 tggtcatctg ccagatcttt ttgataagta tattctggag tcactgcttc tgctgccagt
      661 tttcttcttt gttcggtttc ttccgtgttc tcgatcgttt tattcgcacg gatactctct
      721 tctgctactt ggccttctct gaaatcattg gccttttgtt tgacactact aaatgtaacg
      781 ccgcagacaa tgataaaaaa caagaacaga aggaaaggca atgctgcctt tccgagtttt
      841 tcttgtagtt tctgcagtgt tttattcaac atgtgcttat cctcctaagc aaagcttatt
      901 cttgatgaag atccgccttt tcataagctt tgatgatttc ggcaactaca gggtgccgaa
      961 caacgtcact tgcttcaaaa ttaacaaaat cgattttttt gatttgcttt agtgttcgtt
     1021 ctgcatgaac aagaccactt gtcgtccctc gaggcaagtc tatctgactt gtatccccat
     1081 tgacaatcat ttttgattga taaccgagac gggtcaagaa cattttcatc tgagcgactg
     1141 tcgtgttttg tgcttcgtcc aagataacga atgcatcatc caatgtccgc ccccgcatgt
     1201 aagctaatgg tgcgatttcg attacgcctc gttccatcaa tcggttcgta tgatccaatc
     1261 caaaaatttg gtataaagca tcataaacag gccgcagata aggatccact ttttctttca
     1321 gatccccggg tagaaagcct aggttttccc ctgcctctac agcgggccgc gtcaaaatga
     1381 ttttttgcac ttcgcctttt tttagggcag caattgctaa tactacggca agaaacgttt
     1441 tccctgttcc ggctggccct acaccaaata cgatgtcatg tttggctacc gattcaacgt
     1501 atttcttttg accgctgttt tttacccgta taggttttcc attacggtct ttgacgatct
     1561 cttcctcata catctcaaca aaataatcta atgtaccttt ttgccccatt ttcaatgccg
     1621 tcacgacatc tggtgtactt acgtggattc ctcgtttgat caattcctgt aatgtccgaa
     1681 tgactgaggc agccaaggaa atctgggatt gttcaccaat gatctgaatg atttctccac
     1741 gtgtatggat ggttgtttcc gttgtttcct cgatcagttt tatatgcttg tcgtgtgcac
     1801 ctaaaagcat gctgacatca tcagcagctg tcaatctaat ctctaaagaa ctagactctt
     1861 ccgtcaaaaa tagacatccc ctttttttcg attcattctt tcctatttta ccatactcag
     1921 aagaaactat atagcaaata agaaaaggtt gtaaaagagt cgtttaacca tacgtaccaa
     1981 gaaacgttaa aaaatagctg tttccattcg ctaaaggtct cgttttgata aaaagaatct
     2041 gagaatgtaa gttatatgaa agtggagaac aaaatattcc gtttcattca gaggtattct
     2101 ctaggtattt ttcttgtttc aaaaaaagaa aacaaaatag ttaaaatatt cttgcatttc
     2161 aaaaaaaaca ggtgtattat tacgtcaaca aataaacata cagcaaagcg tcgaggaaaa
     2221 cagtaggcta ttcaacgatt tattcccagt gagtcatgta agtgagaaat gacaataaat
     2281 cgaatagacg aacatcattt ccgagtcaat gtcgaaaacg tagatcattg tggctgcctc
     2341 cattatcagg ctagcggata actttatcaa aaagcgtccg tgaatgaaga agctttttta
     2401 agcgaaaaaa ggtggtaccg ttctagaatc tagagccctt ttcccaagtg gaaaagggct
     2461 tttttttata ttttaaggtg gtggttttca tggaatctga tattagtggc attactaatt
     2521 gctgcaacgt ttatatcgtc aatcaaaatg ataattattg gaggaaaaat ttatggaaga
     2581 aacaaaaact tattcatgga aacaactatt gatggtcagt tcacttatct tcgggatgtt
     2641 tttcgggtca ggtaatctaa tctttcctgt ccacttaggt caaatggctg gcgcaaactg
     2701 ggtcagtgct ggcgtaggat ttgccatctc aggcgctctt ttcccattac tagctatctt
     2761 agctgtagta gtgacaaaaa gtgatggtct gtatgactta gctaaacctg tcggaaaatg
     2821 gtatgctgcc ttgttcttaa tccttgttca tttgacgatc ggaccatttt tcggtacacc
     2881 acggacagct gctactgctt ttgaaatggc tgctaaacca tttttgcctg aaaaatataa
     2941 ttcattaggt atgtttttat tctctgctct tttcttttta cttgcttatt tccttactgt
     3001 ccatcccaca cggttggtca aatacgtcgg aaagtatcta aactccttgt ttcttgcatt
     3061 attagcaatc atttttgtcg tttctttatt ccacccaatg ggaaatctaa atcaatctgc
     3121 tgcagatact taccaaacaa acgctttaac aaatggtgtc ctagaaggtt ataacacggt
     3181 tgatgcagta gccttgcttg ccttaagtgt cacttttgtc catgcagtcc gtgaccttgg
     3241 tttcaaagat aaaaaagtca cagaattaac agcaaaagct ggtagcctga gcgttgcgct
     3301 agaagtcatg atctattttg gtcttgttct tctcggtgcg atgagtttga ataagatgtc
     3361 tttatcagaa aatggcggaa ctgcactttc tcagatcact aatttttatt taggtaactt
     3421 cggcgctagc ttcttaggag tgatggtcac attaggtgtc ttcactaccg ctatgggact
     3481 cgttgtttct tttgcacaag atttccataa actgttccct aaagtcagtt atatgacatg
     3541 gctgcggtta acgactttcg tctcttttgt cgttgcaaat gctggtttgg acaatatcat
     3601 ccaatggtct ttaccagtat tgatgctttt gtatccattg tcgcttgcgt tgattttgct
     3661 ttccttaaca gcaaaatttt tccaaaagac accatttgtc tatcaagtaa cgatgttgtt
     3721 tgctgctgtt cccgccgtat tggatatgct ggcaaattcg cctgctttag tgagtcaaca
     3781 aagagttgta gcaagcatgc tcgaatttta tcatcatcac gttccttttg ctgcattggg
     3841 acttggctgg atggtcccaa cgttacttgg gtatgctggc agcttactct tctattacgc
     3901 ctatcgccta tcagggtata aacaagaagc aaatgaacta ccagaagaat aaccagatca
     3961 aacacaattt aacataagaa atattaaaca ggaaaaaaac agctagatga aagaatccta
     4021 ttctttcgtc tagctatttt ttagatctct tttttacgag cacaaaaaaa ctgcggacaa
     4081 tgattgtccg cagtttaaat gataaaatta agattgtaat agttctttca caatggcatt
     4141 tacttggttt ccatctgctt ttcctttgac tttaggcatg atcgcaccca tgactttgcc
     4201 aaattctttc attgatgaag caccagtttg cgtgattgct tcttgaacaa gttgtcgaat
     4261 ttcttcgtcg gaaagttgtt ccggcatgta tttttcgact atcacaattt cactttttac
     4321 tttttcagct aaatcgtcac gtcctgcttc ttcaaactca tgcaaagaat cacgtcgctg
     4381 tttcatttcg cgagacaaca ccgttaattc ttcttcttct gtcaagtcgt gaccttcttt
     4441 aatctgctcg ttttgtatag atgacttgat cattcggatg acttgtaaag attccttatc
     4501 tttcgctttc atcgctgttt tcatgtcatc gtttaatcta cttagtagtg acacactacc
     4561 aactccaatt catcacagaa ctagaatttt ttgcgttttc tagctgcttc agattttttc
     4621 ttgcgtctta cacttggttt ttcgtagaat tcacgtttac gagattcttg taaagtaccc
     4681 gcttttgaca cggaacgttt gaagcgacga agagcatcgt caagtgattc gtttttgcga
     4741 acgactgttt ttgacatgtt aattccctcc ctccgagctt aaaaagtaac cgtaattgtt
     4801 attgaaatat atctcaaaaa acaagactgt cctgtaaata ttatatctaa tgctgttttg
     4861 accgtcaagg aaatcttgct tttttttaaa attatcaaat gttattttat ttaaatcctt
     4921 attgacaatt ttcacatctt ccgaaaatct cgaatctatg cccttcgatc gtacatccac
     4981 cgagctgttc ttcgaaataa ttcattggac acatatggat ttctttcgtt gttccgcaca
     5041 ccgtacagat aaagtgatgg tgatggccga tttccccttg acagcaatga aaacgaaact
     5101 tcatctctcc atttaaatcg gtttcttcca gtaaatcgat ttctgcaaaa tcatggagat
     5161 ttcgataaat cgtatcgtaa cttactcctt tgaattcctg attcatatag tcaaaaactt
     5221 ctttagcgga tacgtagcga ttgcgcttca ctaaataagt taacaatgct tctctttttt
     5281 tagtatattt aaaaccgtta tttttcaatg tttctagtga ttgttcgatc aacgtctgtt
     5341 ttttcatgac ttattcctcc aaatcaaaat gattacgaag tacacattct agagtatggt
     5401 ataataaaca taaaaaaaat gcaagtgagg ttttatccat gtcttccgat tctacagaaa
     5461 tcgttacttt ttttgtcatc tccgactctg ctggagaaac tgcgacaaaa ctagcgcaag
     5521 ccactatggc ccaatatcct agcgttgagt tcaatttatt ccgcagaaca tttgtgacag
     5581 atgagaaaac attgatgcag gcactgcaag atgcactaga agaaaaagct cttgtcctgc
     5641 acacattgat caatcaagaa ttgatcgaga tgacgcgttc tttttgtgaa gaacatcaat
     5701 tatttagttt tgatgtgatg actccgccga tatcagaaat cgagcgctta actggtatca
     5761 agcccattcg gcaacctggc gcccttcatt tattgaatga gaactatttc aaacggatca
     5821 aagcaatgga atttgctgta aaatacgatg acgggaaaga tcctcgtggg tttctagaag
     5881 cagatgtcgt tttgctaggc gtatcccgaa cttccaaaac gcctttgagc ttgtttttag
     5941 ctaacaaaaa tttaaaagtt gccaatctac ctttgatccc acaagcacat attcccaaac
     6001 agctttggga gatcgatcct aaaaaaatcg tgggactgac gaataaccca gatattttaa
     6061 acaatatccg taaagaacgg atgcgctctt acggattaaa tcctgatact gcttattccg
     6121 atatcgaaaa aatacgagct gaactcgatt ttgcgaatga tctttatgaa aaattgggct
     6181 gcgtagtaat caatgtcgct tctttatcta ttgaagaaac agcttcgctt attttgaatg
     6241 ctttagacct agaagaccat agttattatg gaactgaaac caccgaagaa acagactaac
     6301 aatttttctt taaaaaaact ggactgtgtc agcgaagaag attcgttgac acagtccagt
     6361 ttgtctctat ttgcacctat cgttattgat gttccacatg tttgagtgtc tggttcaaaa
     6421 tatccagtac gtgagaatca tcaagactat acaaaatcgc ttttccctca cgatgggact
     6481 tgacgacatg gttttctctt aataaacgca gttgatgcga tacagcagat tgttccattt
     6541 ccactgcttg gatgattgct gtcacatttt gttccccgtc tttcagatac agcagaattt
     6601 tgagacgagt ggggtcactc aacattttga atagttggct gactttctct acttttgttt
     6661 tttgcgtgtc tggcaatcca ttcacctcca acttgaaaaa agactgactt ctaaagttta
     6721 ccactttttc catcagtctc aagttttttt attcttctgt catcttttgg ataatcgttt
     6781 cataagcggc tactttttca gctgcgtctt ctgaagagtt tccttttaca ccgatataaa
     6841 atttgatttt cggctcagtt cctgaaggac ggatagcgat ccagccattt tcttccagcg
     6901 tatacttcaa tacgtcagat ggcggtgtcg ttagtttttc tacgtttcct tcacggtctg
     6961 ttctcgtcaa ctctttgaag tcttctgttt ggatgacttt tgctccggca aattctgttg
     7021 gtgcttcttc acggaatttt tccatcaaag cagagatttt cgcagaacct tcttgtccgc
     7081 tcattgtcac agaaatcgtt ttttctgcgt agtagccata ggtttcaaaa atcgtttgca
     7141 agccatcata caacgttttg ccttgttttt tatagtaagc tgctacttct gctaataaga
     7201 gcaatgcttg gatcgcgtct ttgtcgcgaa cgaaaggttt aactaaataa ccgtaacttt
     7261 cttcgaatcc gaacataaaa gtatgggaat gatcttcttc aaattgttga attttttcag
     7321 caatgaattt gaatcctgtc aatacattga acatggtagc cccatagtgt tccgcaattg
     7381 ctgtaggtaa ttcgctagaa acgatcgatt tcaataccgc tgcgttttca ggtaaagtgc
     7441 ctcgcgattg gtgtgcttcc aaaatatatt gagcaaacag tgctccgatt tggtttccgg
     7501 tcaatacttc ataggagcca tttggcaaac gaacggctgc acctaaacgg tctgcatcag
     7561 gatctgttgc aatcagcaaa tcagcgcctt ctttctcgcc aagtcgtatc gcatactcaa
     7621 aagcagagtg ttcttctgga tttggtgatt tgactgtagt gaaatctggg tctgcgacag
     7681 cttgttctgg aactagtacg aattgttcga atccagcttg tttcaacgca cgttcgccca
     7741 acatttttcc tgttccgtga agtggtgtgt acacaagttt caaatctttc cccattgttt
     7801 ccaccaattc atgatcaatc gttactgctt tgatttcttc tagataagcg gcatccactt
     7861 cttctccgat gatcgtgatc aatccgctat gttcagcttc ttcgtcagat aatacttcaa
     7921 cttttaacgg attgctgact tcacggacat atttcgtcaa tgcatctgcg tctgcaggag
     7981 gcatttgtcc cccatcttct ccgtagactt tatatccgtt gtaagctgct ggattgtggg
     8041 atgcggttac catgattccc gcaaacgtct tcaaatgacg gactgcaaaa gaaagctctg
     8101 gtgttggacg tagactttcg aatacataag atgggatatt gtgatgtgct aatgttttgg
     8161 ctgcttccat ggcaaattct ggtgattgat ggcgtgagtc ataagcgata gcgacacctc
     8221 ggcgttttgt ttcttcgcct tgtgtatcca tgaaacgtgc aagtccttct gttgcttgtc
     8281 ttaccgtata gatgttcatt cgattgatcc caggccctaa gattccccgc atgcctgcag
     8341 taccgaattc caacggtgca taaaaagcat cttcaagttt ttcaggatct tcacccagat
     8401 catttaattg tttttttaag ttttcttcta aattttcttc atgtacccat tgttcataca
     8461 cttgttccca agacatgaaa ataacacctc tttctgaaat atggttctta ataagtatag
     8521 cattcactta ttagatatga aagtatgagg accaaaaaac gcttaaatca agaaaggatt
     8581 cttttatcaa gcacggttgc aagtattcgc ataaatcgga ttcagtagat ttcacgcgaa
     8641 aaaaaagagt aaaagaacaa ttaaaccgtt cttccactct ttttaaactt atgcagttgt
     8701 ttcttctaaa gattccaagt atttatacac ttgttgtcca gcgatcccac catcaccaac
     8761 agcagtagtg atttgtcgca aatctttttc acgaacatct ccgatggcaa aaacgcctgg
     8821 tatattcgtc ttcatttcgt tgtctgttgg aatccagcca gcttcgttcg tcaaccctgc
     8881 ttctctaaat ggtgcagtta atggatccag tccaacatag atgaatactc cgtctgctgc
     8941 caaatcaaac tcattgccgg ttttgacatt acgtgctttc acacctgtca ctaccatttc
     9001 attcccaacg atttcgtcaa cgactgtatc ccacataaag gaaatttttt cattcgcaaa
     9061 tgcacggtct tggatgatct tttgtgcacg taattcatct ctacggtgga cgatgactac
     9121 ttcagaagca aattgtgtca aatagatggc ttcttctact gctgagtctc ctcctccgat
     9181 cactactaga cgtttgttac ggaaaaacgc accatcacaa actgcacagt aagaaacgcc
     9241 acgtccagca aattcttcct cgccaggtac gcctaattta cggtggatac agcctgttgc
     9301 gataatgact gtttttcctt cgtaagtttt atcttcacaa ataacttctt tgtggctgcc
     9361 gtgatccttg atatcttgca cgattccata agcattttct gtcccaaatc ttgaaacacc
     9421 ttcatacatc ttataagcta gatcaggacc cattattgaa tcgaaaccag gatagttttc
     9481 gatttctgcc gtattgttca tttggccgcc aggggcgcct tgttcgatca tcaatacgga
     9541 taagtttgaa cgtgaagcat ataaagcagc agtcatccca gcaggacctg cgccaataac
     9601 gattacatca tacatatgta gattctcctt tacttaatca agtaagcata ctttacagcc
     9661 aatgcgaaaa aaagtctatt gttctgcttg cgtttctcga atagctttat tatactcgaa
     9721 aaatccgctg aaaaacaata gacttttata aatcattgat caatcattcg aaagattttc
     9781 tccatttgaa tcaattactt ttttatacca gttgaatgat ttcttcttcg aacgggctaa
     9841 tgtgccattt ccttcgttgt cacgatcgac ataaatgaat ccgtaccttt tcttcatctc
     9901 acctgtacca gctgatacta aatcaataca tccccaagtc gtatagccta atagatcgac
     9961 tccatctaat tctactgcat ctttcattgc ctggatatgt gctgccagat agtcgattcg
    10021 atagtcatct tccacataac cattctcatc gggcgtatcg actgcaccta agccgttttc
    10081 tacaataaat agtggttttt gataacgatc ataaatatca ttcatcgtta ttctcaagcc
    10141 taatggatca atttgccaac cccattcact tgcttccaga tatggatttt tgacagaagc
    10201 aaagatattt cctgcagtct gttccaagag ttcgttgtca gtagtcgaaa ctcgagaaga
    10261 ataataagaa aaggagataa aatcaacagt atgttctttc agcaatgcgg catccccagg
    10321 ttccattttg atctgaatgc catttcgttc catttctttc aatgcataag caggatattc
    10381 tcctcgtgac tggacatcaa tgaagaaata attttctcga tctgattttc tagaagccca
    10441 aacatcttca ggattgcaag tgtatggata atatgctcct gctgccagca tacagcctac
    10501 tttgttctcc ggatctactt catgagcaat cttcgttgcg atggcacttg caaccaactc
    10561 atgatgtgcc gcttgatatt tgatttgttc ttcattttct ccttcttcaa aatacagccc
    10621 tgcgcccatg aatggtgcat gaaggatcat attgatctca ttgaatgtca accaatattt
    10681 gacaagtcct ttatagcgat tgaagatgac tcggcacaga ttttcataaa aaccaacgag
    10741 ttctctggaa cgccacgcac catattcttt gatcaaatgc atcggacaat caaaatgtgt
    10801 aatcgtcaca agcggctcga tcccgtactt ttgacattct ttaaagacat cctcataaaa
    10861 tttcaaacca gattcatttg gctctttttc atcgcccatt ggaaaaatac gactccaagc
    10921 aatggacatc cgataagtct tgaaccccat ttctgcaaat aaagcaatat cttccttata
    10981 atgatgatac atatcgatcg caatttttgc tggataaaaa tgattttcat caaattcaaa
    11041 cattttcttt tttccagtaa tgacaggaaa acggtcttct ccgattggca caacatctac
    11101 gttcgctaac ccacgtccgc cttcatcata accgccctcg cattgattgg ctgctgtagc
    11161 tccgccccat aaaaaatctt ttctgaatcc catcatactt cctccattac atgtgtattg
    11221 cttgataatt ctcttgccag ttcatcttgg acttcgattc cttctgcttt taaccggctg
    11281 attgtttcct tgaattgcgg taaatactgc tgatgtgcaa taaacaactc attcatgatc
    11341 cgttttgctg tctttcctga tcgtataagc ggattgatcg taaacgcttg taaagctgtt
    11401 ccataatcac cagtcacagc tgcttcgatc gtcagcaatt ccatattctt cattacttgc
    11461 aaccagcctc tttcagcagc aggaagggaa ccaaacgcta catttcgtgc gccttgtgcg
    11521 ccaacatagg cagtgacttc tactacacaa tctgccggca gatcaggaac agctccatca
    11581 ttctttgtag ataccacgat ctgtgtttct ttatttccat agatcgaagc aatcgtttca
    11641 caggcagcat ctgaataata agcaccacct cgtttttgca attgttcagg tttatgatcc
    11701 aattctggat ctttgtataa ttcaaacagc tctgcttctg tttctttcac ttgctgcgct
    11761 cttgtaccaa tcgtttgata ttcttctaaa gcatgttcca gcatttcttc ttcacggtag
    11821 taatagcggt ggtagccaca agggatcatg ttcatttgtt ttaattgttc tttgaaaaac
    11881 gggatatcaa agatattttt cggcaatcca ttgtcttcat cgtataaacg atcaatcaat
    11941 tctgccgtgc ggtcatttcc tttattatct gctactttgt gccaatggaa gtgatttaga
    12001 ccggcaaact tgtagatcag ctcttctttt ttcttgccaa gcattgttgg ttctgtcatc
    12061 atcgccatta ctggcacatt gcataatcct atcactttat cccatttgcc atatctgata
    12121 actgcttctg tcaccatccc gcttgggttc gcgaaattga tcagccaagc atttggacat
    12181 aaacgcttca tgtcttcaac gattgccaaa accactggaa cggtacgaaa agctttgaat
    12241 atcccgccag caccatttgt ttcttgccca atcatcccat aataactagg gatccgctcg
    12301 tctttgattc gtgcatctaa ttgaccgaca cgaaactgag tcgtaacaaa atccgcatct
    12361 ttcaatgctt cttcccgatc cagagttgca tagattttga cttcatacgg agaagcatcc
    12421 cacatacgct gagacatctg actgacgatc tcaagctttt cttttccttc ttctacatct
    12481 acgagccaga tttctcgtat cggtaattcc tcatatcttt tgataaatcc ttccatcaac
    12541 tcgggggtgt aactgctgcc tccaccaatc gtagcgattt tgattccttt tgccatgttc
    12601 tcactccttt actttttaca cttttattat cttttttgta aacaaaacaa acaatagaaa
    12661 ttcgtttctt tccagtaaca tttacaaaag ttagtgtttt ctactggatt tttgtaaata
    12721 tcttgtcaaa aaatgtcttt attaagctat ataacataaa tccgtttaca aatcattttc
    12781 aaaaaagtta taatttacgt aaaaaaacaa gaagaaggta tctacatgtt attacgtgaa
    12841 aaaatcaaag aaatctcctt ttctccttca gaaaatgaag tgattcagtt tctcttaagc
    12901 gattctccag cacttggcga aatgaccatc caagagattg ctgagcgatg ttatgtccac
    12961 ccgtccacac tcatccgtgt agcaaaaaaa atgggttttg atggctgggt cagttttcgt
    13021 aatgcttttt tagctgaaac agcctatctt gaagggaatt ttcaagacgt agatgcgaat
    13081 cttccttttt ccaccacaga cggtattatg acgatcgcaa ataaaatggc ttctttagaa
    13141 cagatgacga ttcaagatac actttctctc attcatcatg accaactgca aaaagccaaa
    13201 caactaatgc ttcaagcaaa aaaaatcgtg attttcgcca gtaactcgaa tactttgatt
    13261 tctcaagatt tcatgctgaa aatgaagcgc atcaaaatgg atgtcacgat tgtcaccact
    13321 tttggtgaat cgttctatga agcgtacaat tgcacgagtg atatgtgcgg gattctgatt
    13381 tcttatacgg gtgaaaacaa tgtgatcctt cgtaccgcag aaatattgaa acaaaatcat
    13441 gttccaattt tagctttgac cagtatcggt gattcaacgc tatcttcaat gagtacagcc
    13501 gctttgcgac ttacgacacg cgaacgactg tattcgaaaa ttggtaattt tacgatcaat
    13561 acatcgattt gttatcttct agacgtgtta tatagttgtg tttttgcaga aaattatcaa
    13621 cagaatttag tccatctaat ttctgtagga caaaaatttg ataaacgccc tatcagctca
    13681 gccatcatga aagagccttt caattttgaa aataaagaag tggactaaaa agaataatta
    13741 agcctagtcc attctttcac ctaaccgttc aggtcagtgc ggtgataagt gcatcgtctg
    13801 gcccgaccgt ctccccttga ttttccaaaa tatccaaata atccgtgtaa ttggtgacga
    13861 tcacaggtgt ttctaaactg tatccttcct cttcgatttt ctttttgtcg aagcggagca
    13921 acagatcgcc ttgtttcact ctttctcctt gctgcaccaa gctttcaaaa tatttccctt
    13981 ccaactgaac agtatccaat ccgacatgaa tcagcaattc cagacctgct tcagaaacca
    14041 ttccgattgc atgtttcgtc gggaacaggg tcatgactgt tccgtcaaaa ggggcacgta
    14101 cttctccttt ttcagggtag atcaagattc ctcgacctag tgttccttgt gcaaaagctg
    14161 catcctttgc tgcattcagt ggagcgattt gtccttgtat cggtgttttt acaatttctt
    14221 tacctgatct tttctgtcta tcatctgttt cacctgcttc ctccttccaa aagaaaaaag
    14281 tcagcgcaaa ggataccacc atcgcaatgg cgattccaat caatacatta atcacatccg
    14341 ttaaatcacc atctggtcta atatagttgg gaattgtaaa gatgcctaat ccacctggat
    14401 tccaagaagt taaattcatt aatccactat acgcgccccc taacgcacca ccgacacagg
    14461 taaaaataaa tattttttta cgtggcaatg taaacccata aatagctggc tctgtaatcc
    14521 ccacaatacc agaaacaatg gctggtattg cgattgcttt gtcttttggg tttctaagct
    14581 taaagtagag tgcagtaagt gctgcagttt gtccaaaaga cactactgca acaggtgtca
    14641 tgatattttg ccaaccattc acagaaaatt gcatcaatcc cattggtacg attgcccaat
    14701 ggagaccaaa catcactaga atttgccaga agaagcctac gattgctcca taaataactg
    14761 gcgaaagtgc taaaagtgtt tcaaatccag ccattaaaat atcagttgcg aatgtgaatg
    14821 ctggtccaac gagtaaaaaa cctaagggca ttgtaataag aacggtgaag aatggaacga
    14881 agaaattcgc gatcatctca ggtactaact ttttaattgg tttctgaatt tggctagcta
    14941 acaacacaat aaagataatg ggaatgacag aagaagcgta gttacgcgca atccagggaa
    15001 tgccgaatac tgtttgataa ataggtgctt caaaaatagt gccagaaaat atggtagtca
    15061 gtggtgcttc tgctgcacca ctcaaagctt ccagcgacaa gctaggattc attaatgctg
    15121 ccccaagcaa catccctacg aattcattta ctttaaattt acgggcagct gttaaaccga
    15181 taataacagg cataaattgg aatacagaat caccgatatt atcaaacata acaaatgtgc
    15241 cagaaccgcg gtcaaatgcg cctaagaaga caagtaatgc tgtcagtcca cgaatcatcc
    15301 caccagcagc tagaatagca aggaatggct ggaaacagcc cgatattcca tcaataagca
    15361 tatcaaacgg tctcattttt tctgttgaaa cagcctcatc aaaagtaagg tttcctgctt
    15421 ttataacctc ttcaaacacg actggcacat gattcccgat gacaacttgg tactgtcctc
    15481 ccgctcgcat taccgtcaca acaccgtcca tatttttcaa gatctcatca tttgcttttt
    15541 cttcgttttt taatttgaaa cgaagccttg tgatacaatg tgtcaaacca ttgatatttt
    15601 ccttcccgcc gacattttct acaattttgc tcgctaattc ttgatatttt cccatttcta
    15661 ttccctccaa tttattagtg gaaggtttag ccaactgaat gtcactaccc ttatttcatg
    15721 cgttcttgtt aatttatcct ccttttttta tttatttaca acgattctca tgcactaaac
    15781 gcgcaatatg gatcgttaaa tacatttttt cgtccgtgga catctggtag ttgaatatct
    15841 cggctaaaaa gtctgctatt ttctcaacgc aaccaaacgt atccttatat tttttttgaa
    15901 taacctggta caattcctca gaaacttctc ccacttctga tttttctcca tctaggacgc
    15961 gtgtcagaaa aaaacgtagg tgtgtgacga atcgaaaaaa atggactgaa tcttcatcaa
    16021 atgtaatctt atagtaatag cggacgatat ttagaatatc ctgtattgtt gtagtaaaca
    16081 ggtaggtatt gtcttgttgg ctttgaatgc cttgtgcatt gactaaatgc aatgcgataa
    16141 atccggcttc atcttctgat aacttgatgt ggtatttatc cgagattttc ttcactgttt
    16201 ttttcccgat ggcatactct ttaggaaata gttgtttgat atcatacagc aatacatttg
    16261 gtacaaatat tcccattttg tgacgttcga tagccgtata caaatgatcc gtcaatgcaa
    16321 tatacaccga atcattcaac tggacttgta gagcctcttt tgtatattca atgatttcac
    16381 aagaaatttc taagtactca agaggaatcg cttgtgccaa ttcttggaac tgttgtgaaa
    16441 gtccgtcatt tgtcaactga aattttttgt cgatgcatga gtcaaaaatc gggtcaccca
    16501 ctttcttttt gaatgccaaa ccttttccca tcacgatcat ttcctgattt ctttcatccc
    16561 tggttattac gacgttgtta ttcagtactt tctcaatcag catgttttac tcctttccat
    16621 gatatatagg gctgtatcca aaacaaaaag aaaaacccaa aaagccgtcc atggaaccat
    16681 gggagactca tcaggtttag cttgcatcag gcaatcacta tccaagttgt atcgttttct
    16741 ttatattatc gaaagcaagc acttttgtca acgctttctt agcggctatt gggcacttct
    16801 gactagctgt cgtgattttt tttaaatctg gtaattacga cactaacgct cacagatgaa
    16861 gaatctggga agctctgttt tattttcact ctagcgctta ggtcaaaatg ctactatgct
    16921 actgtcccaa cttctaatat acggtgttcc agtaccagct tatcggtgat aagccaaatt
    16981 tatgcaaaaa tctggaaagc cttttttaca atttttttct tatcacctaa agctgaacgg
    17041 agccctgtca caaccacttt ttacacacca ctgctttgca gtttgtacat atctgcatac
    17101 aaaccatttt gcgctagaag tgtttcatga ttcccacgtt ctactatatg acctttgtct
    17161 aaaactaaaa tcaattctgc atcccgaatc gtggacagcc gatgggcaat cgcaatcgtt
    17221 gtccgtcctt gtcgcatttt tgtcaatcct tcttggatca atccttctgt ttcagtatcg
    17281 atatttgctg tcgcttcatc caatactagt attttaggat ctgtcacgat tgttcgcgca
    17341 aaagtgatca gctgtcgttg tccgctagaa tagctggcac cgtgttcgat cacttttgag
    17401 tgatatcctt ttggtaattc atcgatgaac ttgtttgctt gaacaaactc agctgcatgg
    17461 cgaatctgtt cgtctgtgat agttggattc atcatccgga tatttcctgc gatatctcca
    17521 taaaacaaga aggcatcttg caagaccaat cccattttct tacgtaactc ttccattgga
    17581 tattctcgaa tgtcatgatc atcaatcaag atctggcctt cataaaattc gtaaaaccgc
    17641 atcaatacgt tgatgatcga gctttttccg cttccggtgt gccccactaa tgcaacggtc
    17701 tctcccggat tagcgacaaa agagatattg ttcaatacat tgtgctctcc atcataagaa
    17761 aagcttacat tgcgaaactc gatcttacct gaagtaatcg cttgatctgc tccaggattt
    17821 tgttgcggtg catattcttc tgtatccatg attttcaaaa tacgactacc ggcaaccatt
    17881 ccatctgtaa aggtgctcaa aaagtccatc atttgagaca ttggattaaa aaatccctgg
    17941 acataggtcg taaatgcata gatcagtcca acttctacgg gagaatgcag cgcatcgatc
    18001 ccaaacaaag tcaacgccaa cgcaatcgcc aatgcatata gaaaattgat gatcggactt
    18061 aacagaatcg aatttgtttt gatcatcgca tagcgcgtgt ctaaatactc gttgttcact
    18121 tgttcaaatt ctttagctaa acgagcttct tggcgaaact gctggataat acgcatgccg
    18181 gaaatcgatt cattcaattt cgtgttcagc tgacttaatt tttcccgcat attccggtaa
    18241 atacgagaac tgaatttctg gtaataccag atgacgattc ctaaaatcgg caagaacacc
    18301 aaagtccaca aggcaatttc tccattgatt tgaaacatgg caatgaagga agaaacgact
    18361 gcaaagatcc cagtcaatac catcaaaaag acataccaaa attcaaatag cgtttctgtg
    18421 tcatttgtca ctcgagaaac agtcgatcct gccggtgtct gatcaaaata acgcatacct
    18481 agtgtatgca gcttttcaaa taatcttacc cgaacatact gataggtctt caatgaagcc
    18541 atggaataca aataccattg gaaaaaccaa atgatacttt tgactatgac tccaaacaag
    18601 tacataccag caaaaaacaa aataacttgt gtcgtagccg actgtttagc cagatgatca
    18661 tccataaaag tttggatgat ccttggcaat aggacattga tcacagacag ggcaaacgca
    18721 aataagatag caacgatgaa cgttcttcta aaaggtttgg cgaacttcat cagtcgtttg
    18781 atgatcttct tctgttcttt aagtggaatc gattttgtcc attccgattg ataattttca
    18841 tccatcaggc ctcgcctcct tctatcttcg cttctaattt ctgtttctcc cacattcgtt
    18901 cataccagcc gcctaatgca agcagctcat gatgggttcc tcgttcaatg attttccctt
    18961 gatcgacaac aatgatttct tttgcatgca tcacgctgct taaacggtga gctgcaatga
    19021 tggttgtttt ctcttttctt atttctttta aattatgcaa gatagcttct tctgttttgg
    19081 catctactgc agaaagtgca tcatctaaga tcagcaattc aggatttttg atcaatgctc
    19141 gagcaatcga aatcctttgt ttctgtccgc cagataaaga gactccacgt tctccaacta
    19201 aggtatcata accttttggt aattccttga tttcattgtt gataaatgct aaagaagccg
    19261 catgctctac ttcttcttct gaaagttttg gattagaaaa acggatatta tctcgaatgg
    19321 tcatcgaaaa caagaagtga tcttgaggca catagccgat tgatcctaat aaagcattca
    19381 atgaatattc tttgatcgaa catccgccaa attgaatttt tccttgataa tcatcgtatt
    19441 cacgcatcag taatttgatg attgtcgttt ttcccgcacc agttttccca acaataccta
    19501 atgtttctcc ttcttggatc gcaaatttga tttgttctaa tgctggtgat tcttctttcg
    19561 gatagttaaa agaggaaata gctacattca gctcgccttt tgccggagtc tgcactgcac
    19621 ccagttgttc cacgatatgc gtcttttcat gcaaaagttc attgacgcga tcataagaag
    19681 catttcctct ttccaatacg ttgaacaatc gaccaatcgc aaacatcggc caaacaagca
    19741 taccgatata gctaataaat gagaccatct gcccgattga gatcgtgcct tccaagacat
    19801 actttccacc taaaataatt gttgcaacat aagacagacc gataatcaag gtaatgaatg
    19861 gatcaaataa ggagtctaaa aaattgactc gtttgttttt aataattgca tcttcaatct
    19921 tttcttcaaa atccgcgaga tcttcttttt cttgtccaaa tgttttaatg actttgatcc
    19981 cagtaatact ttcttgtgtc ttatcattga tactagaaaa agcttcttgc gaatcacgaa
    20041 aagcatcgtg gagttttgac cccagcactc gtgaagtaac ggctagtaaa ggcagaggaa
    20101 tcagcgcaat cagtgttaag cgccaatcaa taaacaaaat catcgcaatg atcgttgttc
    20161 cgcccgtgat cactgaatct gcaaaggtca agataccagc tcctgctaca ttttggattg
    20221 cattcaaatc attcgttgca tgagccatca aatctccagt ccgatatttt tggtaaaaga
    20281 gattgtccat ttctgtaaaa tgtttgaata gctgctgccg aagttctttc tccaaccgag
    20341 ctgcacttcc ccaaatattc gtccgccaga tataacgaaa aagatattgt aagagagctg
    20401 caaggatcaa taataagatc caccaggaaa tgatctttat tgataaattt ttatcggcga
    20461 tctcatcaat gatgatccca atcacttttg gaggagctaa ctgtaccaag gccactgcga
    20521 atagggagaa aatcccaatt aaataatgtt tcttttcctg tcgaaaaaac caacctaatt
    20581 ttctaaaaat cgacatttta ctcctccttt gtctttatca agagcatagg attgtctgtg
    20641 cttgtctttt ttgctgaata gtctgaatag tctaacaaat tacgaaataa aaaacggact
    20701 gaaaaaatca gcccgcaaaa agtctttggg tcagaaccta ttttttccct tggttcttca
    20761 tttgctgcat catctggcga attttcttct cagatggttt ttgccccatt gacatcatca
    20821 ttgatcgcaa catgtcctca ttaacgggag gatttttttc taaatagtct ttcatatatt
    20881 tacgcgctag gaaaaagcca cctactgcgc cgattagcaa agcaataata gcaataagta
    20941 cgacaatacc tgttgatacc atataaatct ctcctttcta tttccgaatt gctctcaatg
    21001 atttatttta ctaaagttta ttgaaaaaag aaaggcgtat tctttagttt catgcaaaaa
    21061 atagtggttt ttttagagaa gaacaaaatt tctttcatta accagcaaga cacgccacga
    21121 aaaaaaatta ggcataccaa atctttttct ttaatttttt ctttctgagg tgtagaatgt
    21181 aatcgtagat aaataggaaa ggtggttttt tcttgaataa tcaatccaac aaacaatttc
    21241 ataagcatcg acttattgaa catacaaatg gtttatcttt agctgaagta aatggaacag
    21301 tggatgtacc caagggaaaa agttttttta aaacacttct tgcttactct ggaccaggtg
    21361 cattagtagc agttggttat atggatccag gtaactggtc cacttcgatc actggtggac
    21421 aaaatttcca atatttattg atgtcagtta ttttgatgtc tagtctgatt gctatgcttt
    21481 tacaatatat ggcagcaaaa ttaggaatcg tgacccaaat ggatttggcc caagcaatcc
    21541 gagcacggac aagtaagaca ttgggtgtca ttttatggat cttgactgaa ttagccatta
    21601 tggcaacaga catcgcagaa gtcattggtg cagcaatcgc cctctacctg ctttttgata
    21661 ttccattggt aattgccgta tttatcactg tgttagatgt tttcgtcctt ttattgctga
    21721 caaaagtcgg gtttcgtaaa atcgaagctt tggttgtctg cttgattttc gtcattttat
    21781 tcgttttcgt ctatcaagtt ggcttgtcta accctgattg gcacagtttg tttgccggat
    21841 ttatccctaa cagtcacaca ttctcagact caccggtcat cggcggcgaa actccgctga
    21901 ctggagcttt agggattatt ggtgcaacag tcatgccgca taacttatat cttcattcag
    21961 cagtttctca aactcggaag atcgatcacc aagacgaaga agatgtagca caagcggtac
    22021 gcttttctac ttgggattct aatatccagt tgtcaatggc ttttctagtc aatgcactgc
    22081 tattgatcat gggtgtggct gtattcaaaa ccggttctgt ccaagatcct tccttttttg
    22141 gtctgtatga agctttatct gatccatcag ctatgagcaa tggtatcttg attgctgtag
    22201 caaaatctgg tatcttgtct actttatttg ctgtagcact tcttgcttct ggccagaact
    22261 ctactattac tggtacgttg accggtcaag tcatcatgga aggcttcatc catatgcgta
    22321 tcccaatttg gctaagaaga ctagtcacac gattgctttc tgtgattcct gtattgattt
    22381 gtgttttgtt tacaagtaca aaaggaacga tcgaagaaca taccgctttg aataacttga
    22441 tgaatgaatc ccaagttttt ctggcttttg cattgccatt ctcgatgatt cctttactga
    22501 tgatgaccaa tagccaagcg gagatgggga gccgattcaa aaattcattt gttgtaaaac
    22561 tacttggctg gttctctgtg attagtctga cttacttgaa tttacgagga ttaccaggtc
    22621 aaatcgaaag tttcttcggc gagcaagcca cctcagctca actagcattg gctgatcaaa
    22681 tcgcttatgt aatcattgtt cttgtccttc tcctgttggc atggacgatt ggtgatttat
    22741 ataaaggaaa caaaaaatat gaacagcgtt tgcaggaaac gatagaagaa atcgagtaga
    22801 aactgattct tttacacaaa ggaggttgtg tcagaagtgg gcagcttcaa gaaataagaa
    22861 ggaatttaag aaaattgctt ttcaaatttt tgtgaaattt cggcttattt ccgaagaagt
    22921 tacttctgga acaccgtgta tcagaggttg tgaaaaagct gccttgcatc aagtaataag
    22981 aacagccaag taaaaacagc tttttatgtt tttaacttgg ttggacttat taccgcagat
    23041 gcaagctttt gagcaccgtt tattcggaaa aaggaactgc gacaagactt ttgtcacagt
    23101 tccctttcct acgattagtc aagtaaaagg tgtaagaaaa atagctcata aacgaaagcg
    23161 acaaaatcaa
//
LOCUS       DAFLWQ010000042        23165 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.043, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000042 DAFLWQ010000000
VERSION     DAFLWQ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23165
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.043"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            38..895
                     /locus_tag="L1V16_001639"
     CDS             38..895
                     /locus_tag="L1V16_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBN1275982.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1010..1930
                     /gene="pstC"
                     /locus_tag="L1V16_001640"
     CDS             1010..1930
                     /gene="pstC"
                     /locus_tag="L1V16_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBN1275983.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            1930..2814
                     /gene="pstA"
                     /locus_tag="L1V16_001641"
     CDS             1930..2814
                     /gene="pstA"
                     /locus_tag="L1V16_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBN1275984.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            2829..3635
                     /gene="pstB"
                     /locus_tag="L1V16_001642"
     CDS             2829..3635
                     /gene="pstB"
                     /locus_tag="L1V16_001642"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBN1275985.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3651..4409
                     /locus_tag="L1V16_001643"
     CDS             3651..4409
                     /locus_tag="L1V16_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBN1275986.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGINLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4422..5099
                     /gene="phoU"
                     /locus_tag="L1V16_001644"
     CDS             4422..5099
                     /gene="phoU"
                     /locus_tag="L1V16_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBN1275987.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5337..5636
                     /locus_tag="L1V16_001645"
     CDS             5337..5636
                     /locus_tag="L1V16_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1275988.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKK"
     gene            5662..6369
                     /locus_tag="L1V16_001646"
     CDS             5662..6369
                     /locus_tag="L1V16_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBN1275989.1"
                     /translation="MSIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLL
                     NISILFVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYE
                     ELNYLTRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQV
                     GRDVIGSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVL
                     SIPISVLFFLTVRRLKR"
     gene            6366..7133
                     /locus_tag="L1V16_001647"
     CDS             6366..7133
                     /locus_tag="L1V16_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBN1275990.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7233..8801
                     /gene="liaX"
                     /locus_tag="L1V16_001648"
     CDS             7233..8801
                     /gene="liaX"
                     /locus_tag="L1V16_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HBN1275991.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEITQVQL
                     STTTGSIYLKDTDK"
     gene            9098..9418
                     /locus_tag="L1V16_001649"
     CDS             9098..9418
                     /locus_tag="L1V16_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HBN1275992.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            9418..9768
                     /locus_tag="L1V16_001650"
     CDS             9418..9768
                     /locus_tag="L1V16_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBN1275993.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            9935..10873
                     /locus_tag="L1V16_001651"
     CDS             9935..10873
                     /locus_tag="L1V16_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBN1275994.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            10888..11718
                     /locus_tag="L1V16_001652"
     CDS             10888..11718
                     /locus_tag="L1V16_001652"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBN1275995.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11762..12787
                     /locus_tag="L1V16_001653"
     CDS             11762..12787
                     /locus_tag="L1V16_001653"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBN1275996.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12802..13740
                     /gene="galU"
                     /locus_tag="L1V16_001654"
     CDS             12802..13740
                     /gene="galU"
                     /locus_tag="L1V16_001654"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBN1275997.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKKLEAEGSKIDHNPKGITEIKEEKKK"
     gene            13865..14305
                     /locus_tag="L1V16_001655"
     CDS             13865..14305
                     /locus_tag="L1V16_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBN1275998.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14308..14910
                     /locus_tag="L1V16_001656"
     CDS             14308..14910
                     /locus_tag="L1V16_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBN1275999.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDTKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(14978..16084)
                     /locus_tag="L1V16_001657"
     CDS             complement(14978..16084)
                     /locus_tag="L1V16_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBN1276000.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLASIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16294..17295
                     /gene="ccpA"
                     /locus_tag="L1V16_001658"
     CDS             16294..17295
                     /gene="ccpA"
                     /locus_tag="L1V16_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HBN1276001.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(17631..19976)
                     /locus_tag="L1V16_001659"
     CDS             complement(17631..19976)
                     /locus_tag="L1V16_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBN1276002.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            20255..21157
                     /locus_tag="L1V16_001660"
     CDS             20255..21157
                     /locus_tag="L1V16_001660"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBN1276003.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            21370..23145
                     /locus_tag="L1V16_001661"
     CDS             21370..23145
                     /locus_tag="L1V16_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBN1276004.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYSSSKKMLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYSIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHAVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFAFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTAFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
BASE COUNT         7377 a         4123 c         4894 g         6771 t
ORIGIN      
        1 taaaataaac atactttagg attaaaggag atttctaatg aaaaaactta aattattctt
       61 accaataata ggattagcca ttcttttatc aggctgttca aagtggattg atcgaggaga
      121 atccattacg gctgttggct cttctgcttt acagccttta gtagaaacag ttgctgaaac
      181 ttaccagaca gaaaatcctg gaaaattcat caatgtacaa gggggcggaa gcggaactgg
      241 tttgtctcaa gtacagtcag gagcagtcga catcggaaac tctgatttgt ttgcggaaga
      301 aaaatcgggg atcgatgcct cagcattagt cgatcatcga gtagcagttg ttgggatcac
      361 tcctattgtg aacaaggata ttggcgtaaa agacatcagt atggaaaacc tgaaaaaact
      421 atttacaggc gagatcaaaa actggagtga agtcggtgga aaagatcagc cagtagttat
      481 attgaaccgc gcttcaggaa gcggaacccg tagcacgttt gaaaaatggg tattggacgg
      541 agaaacagct gttcaggcac aagaacaaga ttcaagcgga atggtgcgcc agatcgttgc
      601 cgacacaccc ggtgcaatca gctatgttgc tttttcttat gtttccgatg atgtagatac
      661 gttgaatgtt aacggtgtag aaccgacaga tgaaaatgtg acaacgaaca aatggacgat
      721 ttgggcatat gagcatatgt acacaagaga tcatccaaaa aaactgacaa aagaattttt
      781 agactatatc ttatctgatg aagtacaaga taacatcgtt ggagaactag gttatatccc
      841 tgtttctcat atgaaagtcg aacgtgattg gcaaggaaat atcgttaaag agtaatcttt
      901 acacaaaatt tacaaactta gctaaacttt tacatgttat taaaaccaaa ttgatgttca
      961 atttgtacac tgagtgagta tgttaaacct gattaagggg gagtcatctg tggaagatgt
     1021 gaaaaaagta ttattaacaa aatcaaaacg ttcaaaaatg gaacagcgtg gaaaattcat
     1081 cagtttttta tgtatcgcgc tgatcgtgtt ggttgtatta tctatttttt attttgtagc
     1141 tagtaaagga ttggccacct tttttactga taagatcaat gtatttgatt ttctgtttgg
     1201 tacagattgg aatccaagcc aaatcggagc aaatgggaaa ccaatggtag gggcattgcc
     1261 tatgatcaca ggttcgttta ttgtgacctt tttatctgct atcgttgcca cgccatttgc
     1321 cattggtgca gcagtattca tgacggagat ctctcctaaa aacggaacga agatcttaca
     1381 gccggtcatc gagctgcttg taggtattcc ttctgtcgtt tatggtttta tcggtttatc
     1441 agttatcgtg ccttttgtca gaagtatttt tggcgggaca gggtttggta tcttagctgg
     1501 tacatttgtg ttgttcgtta tgatcttgcc gactgtcaca acgatgactg ttgatgcatt
     1561 aaaggcagtg ccacggcact atcgggaagc ttcattagcg cttggtgcca caagatggca
     1621 aacaatctac aaagtcgtgc tacgagcagc cgtgcccggg attttaacag cagtcgtttt
     1681 tggtatggct cgtgcgtttg gtgaagcctt agctatccaa atggtcatcg gtaatgcagc
     1741 attgatgcca acaggactta ctactcctgc ttctacattg acgtccatct taacaatggg
     1801 aatcggaaat acaatcatgg gaacagttga aaataatgtg ttatggtcat tagcgctgat
     1861 cttgctattg atgtcattat tctttaatat cgtgatccgt atgattggga agaaaggaga
     1921 gctgaaataa tgaacgcaaa acgctcagat aaaattgcta caggtgtttt atatatagtt
     1981 tcggggatca tcgtattgat tttagcagct ttactacttt atatcttagt tcggggaata
     2041 ccgcatattt catggtcctt cttgaccgaa ccttccaaag cctaccaaga aggcggtgga
     2101 atcgggatcc agctatttaa ctcgatttat ttgcttttga tcacgatgat catcagtttt
     2161 cctatttctt taggtgcggg tatctatctt tcagaatatg ctggaaaaaa ctggctaaca
     2221 gatgtgattc gcacgtcgat tgaaatcttg agctcgttgc cttctgtcgt tgtcggttta
     2281 ttcggtttct tggttttcgt tattcaattc cagtatggtt tctcgattat ttctggtgca
     2341 ttggctttga ctgtattcaa cttgcctctt ttgactagaa cagttgagga gtctttacaa
     2401 gcggtccatt acacacaacg agaagcagga ttggccttag gtttgtcacg ctgggaaaca
     2461 gtgataaaag tggtggttcc agaagcgaca ccagggattt tgactggtgt gatcctaagt
     2521 tctggaagaa tttttggtga agcagctgca ttgatctata cggctggaca aagtgcacct
     2581 gcgttagatt ttacgaactg gaatccatta agtgtttcaa gcccgatcag cattttccgt
     2641 caagctgaaa cattagctgt ccatatttgg aagatcaata cagaaggcac gatgcctgat
     2701 ggtgtttctg tttcggctgg cgcttctgcc gtgttgatca ttgctgtttt actgttcaac
     2761 ttcggcgctc gtgcgattgg caaacgatta taccgaaaaa tgacttcagc ctaaggagaa
     2821 gaagcaaaat gaaaaaatat aactggaatg aaacaaatgt catcaccatg ccaaaagaga
     2881 aagaagtagc actatatacg gatgatctac atgtctggta tggcgacaat gaagcaatca
     2941 aaggagtgga tctggaattt gaaaaaaata agatcactgc actgattggt ccttccggct
     3001 gcggaaaatc tacgtatctt cgttcgttga atcgaatgaa tgatgggatc gctaatacga
     3061 aaatcactgg gaaaatcatg tatcaaggcg tagatattaa tgcgcctcaa gtggatgttt
     3121 atgagatgcg caaacggatt ggcatggttt ttcaacgtcc taatccgttc agcaagtcga
     3181 tttatgacaa tattacattt gctttgaaac agcacggcga aaaaaacaaa aagaaattag
     3241 atgaaatcgt tgaaacaagc ttgaaacaag ctgccttgtg ggaccaagta aaagacagct
     3301 tggacaaaag tgccttggct ttatctggcg ggcaacagca acgtttatgt attgctcgtg
     3361 cgatcgcgat gaaacctgat atcttgctgc tagacgagcc ggcaagtgct ttggacccta
     3421 tttcgacagg aacggttgaa gaaacacttg taaacttgaa agaagactat acgatcatca
     3481 tcgtgacgca taacatgcaa caagcagctc gtatcagcga ctatactgcc tttttctatc
     3541 taggaaaagt aatggaatat gacaaaacta acaagatatt taccagacca aaaattcagg
     3601 caaccgaaga ttatgtgtcc ggtcattttg gttaagacgg aggcctcaac atgacaaaag
     3661 aaattatttc atctaaagat cttcatctgt attatggaaa gaaagaagca ctaaaaggga
     3721 tcaatctaag tttcaatcaa ggggaaatca ctgcgatgat cggtccttct ggttgcggga
     3781 aatccactta tctgcgttct ttgaaccgga tgaatgacct gattccgaat gtaacgatca
     3841 ccggaagtgt tttatataaa gacaaagaca tctatggtcc aaaaacagat gttgttgaac
     3901 taagaaaaga aatcggcatg gtattccagc agccaaaccc atttcctttt tctatctatg
     3961 aaaatgtcat ctatggattg aaattaaaag gggaaaaaga taaaaaagtc cttgatcaag
     4021 tagttgaaga aagcctgaag gcagcgtctg tttgggatga tgtgaaagac aaattgcata
     4081 aaagtgcttt atctttatcc ggtgggcagc agcagcgtgt atgtatcgca cgtgttttgg
     4141 cagttaatcc ggaaatcatc ttattggatg aaccaacaag tgcgcttgat cctgtttcta
     4201 ctgggaaaat cgaaagtatg ctgttagaat taagagagcg gtatacgatg atcatcgtga
     4261 cccataatat gtctcaagct tcacgtattt cagataagac ggcattcttt ttagatggtc
     4321 acttgatcga atacaacgat acgaagaaga tattcatgaa tccagaaaaa caagagacag
     4381 aagattatat ttcaggtcga tttggataag gaggaaacgg aatgctacgt acacaatttg
     4441 aagaagaatt gctgaatctc cataatcagt tctacgaaat ggggatgatg gtgagcagcg
     4501 ccgtgcacaa gtcagttcgt gcatacatca aacacgataa aatcttagcc caagaagtta
     4561 tcgaaaacga tataaatatc aataacatgg aaacacgctt ggagaagaaa agttttgaaa
     4621 tgatcgcatt gcaacagcca gttacaactg atttgcgtat gatcattacg gtcatgaaag
     4681 ctagctcgga tttagaacgt atggccgatc atgcggtgtc tgttgctaaa tccacgattc
     4741 gcgtaaaagg gcagacgaga ataccggaaa tcgaaaaaga gatctccgat atgtccgatt
     4801 atgtgaaaaa aatggtggac aacgtcctag ttgcttatgt caaaacagac gaaaaagacg
     4861 cacgtacgat cgccaatatg gatcaaagag tcaatgacta tttcaatcga atctataatg
     4921 caacaatcaa aaatatgcag gaaaatcctg agacagtcat cagtggaaca gactacttga
     4981 atgttgccag ttatctagaa cggatcggag actatgtgac aaacatctgt gaatggatcg
     5041 tctacttggc tacagggaaa atcactgagt taaatacgaa ccacaatgag attttctaaa
     5101 ctgaagctgt gattatgccg tttgtttagg aaaagaggtt gtgaaatcag cggttgtgaa
     5161 aaagctgttc tgcatcaagt aataagaaca gtcaaacaaa aaatagctcc tcatattttt
     5221 cgtttggctg gacttattac cgcagatgca agcttttgaa caccgtttat tcgggaaagg
     5281 gtttgtgaca aaacatgtca caaacccttt tcatcatttc atagaaagga taaagaatgc
     5341 aaaaaaaaat tagcatcatc actatatttt ttatttgtgt gcttacttca tgggttattc
     5401 agcatcaagc tgctttatat gaagtacctg tcatcgagat cgaaaaagta cgaataaaag
     5461 aggatcatca attgattaca ggaagactga tgaacacgga tcaaaaagga gaatcgattt
     5521 atttatcggt tccttatcaa aaaaatcaaa tagaaacagc aaatataaaa gcgagacaaa
     5581 tgtatctagt ccaaatgcat ggagatgaat ggcagctagt agcaaaaaaa aaatgatggc
     5641 tggcttttct tcttcacaag tatctccatt ggcgccatgt tgcttattgg cggaaaacag
     5701 ggtctatttg ctttaggaag tctcatcatc aatatcgttt tacttttact tttgttgctc
     5761 atctttacta aaacagaagg gatttctcta ttaaatatat ctatcctgtt cgtcgttata
     5821 gggatgatta ttagcatatt ggctttagat ggatggaata gaagcagtat aatcaaaatt
     5881 tcagctgcag ttacgagtgt ttttttagca ttttttattt gtcttttgac aatgaatcat
     5941 tggaaagacc aaggactgcg ctatgaggaa ctgaattatc tgacacgacc gtatcgttct
     6001 gtttttcttt ctagcgtact gattggaaca gctggaggaa cactcgatac cgttatcaca
     6061 gtcattgcga cattagaaga attgactaag cgacaaccag aaataacagc gaaacagtta
     6121 tggctttcag gaaggcaagt gggtcgagat gtgattggct cgatgaccaa tatccttttg
     6181 ttcgtctata tcagtgggtc agttccatcg cttcttttat atttaggaaa tcaatggtcg
     6241 ttcaaagaaa cgatagaaca gcatttatca ttggaatttt tacgcgtcat tgctggcagc
     6301 ttaggaatag tattatcgat ccctatctcg gtcctctttt ttctgactgt aaggaggctg
     6361 aaacgatgaa tgtacttatt atacttgttg ggattttagc aatcagcgtg ctacttattg
     6421 gcggtacgca aggtatgtat attcttttag gcttattcat caatttaggg atctttttcc
     6481 tgttgttatt cggttatcat cagaagtggc cgatactggc attgtcggtc ataggatttt
     6541 tattgattgc tgtggttatc ttatttttta tcaacggtta taatctaaaa atgcgtgcag
     6601 cttttgtgag tatactgatc tttttatttt gtttcctact attgcttcct atcactgatt
     6661 ttttagcgat ccaaggtttt acatcggtag aactagaaga attatctggc ttagataaga
     6721 ctttagcgat tgattttaga ttacttacga gatcgttgct tctgattagt cttagtggtg
     6781 ctgttttaga tgctagtgta gcaatttcta gtgggacatt cgaagtatat caggcaaatc
     6841 cgcaattatc tttttaccaa ttgcgccatt ctagtttcgc tattgctaaa aaaatattgg
     6901 cgtcaacagt aatgacactt ctttttgcat tcatgggaag ttctttagcg ttgatcctct
     6961 ggtttattga tttagacatt ccttttcagc aagtgatcaa tgaaaaatca tttgttctag
     7021 aatatacgat ggctattctt accacattgt ctgcactact tgttcttcct ttaacctgcg
     7081 tgactacagc atatctcttt acaaaaaaga aagaacaact caagatggag taaaagttac
     7141 aacttaagtc ctatgacatt tttactgaat cagtgcataa tatggatgta aggaaaagct
     7201 tgcaaacaat tttgcttaag gaggcaattt ccatgaaaga aagagaacgt attttagatt
     7261 tagtgaaaaa aggaatcctt tcgactgaag aaggcttaga tttattagaa agcatggcaa
     7321 ctgaaaaaga cgaaaagcaa ataaaaaaag aagcagacaa ggtaactgct agtcataaag
     7381 aaaaagatca ggcaagtcaa ttgatcgata aacttgaaaa cggcgaagaa gaaatttctg
     7441 agccagttga tccaaaggaa agagaaaggc aagatcaaga aaacttagaa aagatcttag
     7501 atgaactagc aactgaagcg aataaaactt cggcgcgtct agatgaagta aatgctcaat
     7561 tcgctgacaa taaggcagca cgcaatgaga aacaggaagc attgatgcag ctgaatacaa
     7621 aagaagaatt aggcgagttg acagaagaag aattagcaca gcgtcagacg ttagaagcag
     7681 aaatcaaaga attagaagct agtggcgata cactgttaga agaacaattg aaattagaag
     7741 cagaattaaa agatatccgt aagaatcaat ggtctgagaa aaaagaaacg tttactgata
     7801 agtttgaatt gccagatgat tggaaagatc aagcaacaga tacactgaat caagtaggcg
     7861 aaaaaatgtc agaagctgga tcacagttag gcaaattctt gaagaaaaca ttccaaactg
     7921 tttcagaaac agtgaatgac aacatggaat ggaaagatgt cagcttacgt gtccctggga
     7981 ttgcgacaac gaaatttgag catgaatttt actatgaagc tcctgcagca agtatccttg
     8041 atatcaaggc agcaaacgga aacgtgacgt taaaaacgtg ggacagcaac gatgtgaaag
     8101 ttgaagctaa gatcaaactt tacggaaaaa tgggtgctga accatttgaa gcattctctg
     8161 aacggagcca gattgaggtt aatgaagatc atatctcctt ccaaattcca aataaacgtg
     8221 tgcgtgcaga ccttgttttc tacttaccta aacgagtata cgaccacgca gctattaaac
     8281 ttctaaatgg caacatcatg attgaaacat tggaagctaa agatatttat acaaaatcta
     8341 cgaatggtaa catcatcgtg gaccaattaa ctgcaacgat gctggaagta gaaggtgtaa
     8401 acggcaatat cgatattcga aacgggaaca tcttagattc tattatcgaa acagtaaatg
     8461 gtacagtgac atttggtgcg acagcagaaa acctttctgt gtctttggta aatggtgatg
     8521 tacgtcttac gattaaagaa gataatttga aaaaagtaga agcaagttca gtgaacggaa
     8581 atgtcaaagt cgctttacca gatggcatcg gtttggaagg acatgctaaa acaagtcttg
     8641 gaagtatcaa cagccgtctg tccaattacg aagtagttcg tgagaaaaaa gaacggacaa
     8701 accaaatgtt gcaattccgt cgtgtttcag atggtgaaat cacgcaagtg caactttcaa
     8761 cgacaacagg aagtatctat ttaaaagata cagataaata aagaggttgt gaaagagatg
     8821 ttcagccttg agcaataaga agcgattttg taaaatagct tcccctattt tacaaaattg
     8881 tgccttattg ccgataggct atctcttgaa caccgtttac caagagatta tgaacctgcc
     8941 aattatcgcc gagtcacaag gaataatttc agaaaaagct cgtcacgttt tatgaatatg
     9001 gtaatttgtg accgagaatt ttgcagaaag acaccgatta agaagaaggt tgtcacaacg
     9061 attttcttca tttaaaatag tagaacagag gtgagacatg atgaaaaaaa agttgacaaa
     9121 atccaataaa aatgttgttt tgacagggac tttagcagga ataggagaat acatcgggat
     9181 tgatccgact gttatccgtg tgctttatgt attcctgagc ttagttgctt ttggaagtcc
     9241 aatcatttta tacattttat tagctttgat tatcccatct gcgcgttctg cacgaacaaa
     9301 ctatggacat aacaatgcat attatgaaaa aaacaattat cgtgaacaaa ctcgtgaaca
     9361 aacaaaaaaa cgcaaagaag cggaaaaaat cgatgatgac gaatggagtg acttttaatg
     9421 tcgtactttc aacgtatttt agttaatacg ttaacattca tatcattggc tgttcttttt
     9481 cctgcgatgg tccatgtgag cagtatttgg acggccgttc ttgccagctt cgtattgtct
     9541 gtgttgaata tgtttgtcaa accgattttg acgatactgt ccctgccctt tacattagtc
     9601 acattgggat tgtttacgtt tgttatcaat gcagcgattc ttaaaatgac ctcctttttt
     9661 gtgggagcag aacattttag tttttcttca ttcggtgcag cgttgttagt agctatcttg
     9721 atgtcgcttg tcaatgtaat tgtcagtgaa cataacagta gaaaataaaa gaaagctgtg
     9781 ccgaactatc ggcgcagttt ttttatttag aatcaggaat gcgttttcta ttacattggt
     9841 aattaaataa aaacgttttt tttaattggt agtacttttg gctagacaat gataaaatga
     9901 tagagaacac tctaatagaa atgaggtagc atgaatgtca gaagttgtaa aagttagcca
     9961 attagtgaaa aaattatctt tggaaatcgt gacaggcgac gagaaaagct tagaccgtgt
    10021 catcgtaact ggggacatct cacgcccagg actagagttg actggttatt ttaattatta
    10081 ttcccataat cgtttacagc tatttggcag taaagaaatc agttttgcgg aacggatgat
    10141 cccagaagag cgtttgatca tcatgagaag attatgtagt gaagatatgc ccgcatttat
    10201 tatttcaaga ggattaccgg ctccagaaga aatgatccag gcagcaaatg aaaatgggat
    10261 agctgtactg cgttctccca tctcaacttc tcgtttatta ggagaattat ccagttattt
    10321 agatggtcgc cttgcccctc gaacaagtgt ccacggtgtt ttagtggatg tttacggatt
    10381 aggtgtactg attcaaggtg acagtgggat aggaaaaagt gaaacagcgt tggagttgat
    10441 caaacgcggt catcgattga tcgcagacga tcgagtagat gtttatcagc aagatgaatt
    10501 aacggtgatc ggagaaccgc ctaaaatcct ggaacatcta attgaaatcc gaggaatcgg
    10561 gatcattgat gtaatgaatc tttttggtgc gagtgcggta cgtggctcta tgcaagtcca
    10621 gttggctgtt tatctggaag catgggcaaa agataagaaa tacgaccgtc tgggctctga
    10681 agacacgacc gttgaaatcg cggaagtggg cattccacaa ataaaaatcc ctgtcaaaac
    10741 aggacgaaac gttgcaatca tcattgaagt agccgcgatg aatttccgtg cacgtacaat
    10801 gggctttgac gcaacgaaaa catttgaaga aagattaagt cgcttgattg aagaaaactc
    10861 aggcaacgac tagcaaggag tgacaatatg ttagcacaaa tcaatcgagt tgcttttgag
    10921 cttgtaggga ttcctatcta ctggtatgca ttgatcatcg tatcaggtat cattatcgcc
    10981 atgtggctta gcagcagaga ggctgttcgg gtaggattaa aagcagatga tgtgacagat
    11041 tttatgttgt ggggattgcc tatctccatt attggtgctc gcttatatta tgttttattt
    11101 gatcttcccc agtatatagc tgatccaatc caaatattca atatccgttc aggaggctta
    11161 gctatttatg gcggactgat tgcaggcgcg atcacgctgt atttttttac taaatatcat
    11221 tttatttctt tgtggacttt tttagatatc gctgcaccaa gtgtattatt agcacaggca
    11281 atcggtcgtt ggggaaattt catgaaccac gaagcatatg gaccagacac gacgcgaagc
    11341 ttcttagaaa gtctgcattt accgcaattc atcattgata atatgtatat cgaagggatc
    11401 tatcgtcaac caacatttct ttatgaatca ctttggagtt tgattggatt tattttgctt
    11461 ttgtttttac gaaagaaacc acaccttttg aaaaaaggcg aagtcctttt atgttatcta
    11521 atgtggtata gtttcgggcg tttctttatt gaaggattac gtacagacag tctttacttt
    11581 ttaggtgtga tccgtatttc tcaattatta tctgctgtgt tatttgtcgg tacattgatt
    11641 ctatttattt ggcgcagaaa aaaaggaaat ttaccggatt atgaccgctc attaggaaaa
    11701 aatcaacaaa ttatctgatt tttagagcgt taaaaatgaa aaaaatttca ggagtggtaa
    11761 aatgaattat agagtagcgg ttttaggacc aggctcttgg ggtactgctt tggcacaagt
    11821 cctcgccgaa aacggacatg acgttcggat ttggggacat cgtgcttcac aagtagaaga
    11881 aatcaacacc caacacacga atcaacgtta tttaccagat cattatctac ccgattccat
    11941 ccaagcattc accaatatgg aagatgcagt aaaagacgca gatgcggtgc tattcgtcat
    12001 tccaacgaaa gcaatacgtt ctgttgcaaa agaactagtg cctaaattga atacaaagcc
    12061 agtgatcatc catgcaagta aaggattaga acagggaaca cataaaagga tctctgacat
    12121 cttgttagag gaaatcccag cagaaaaaag aaaagctgtt gttgttcttt ctggaccaag
    12181 ccatgcagaa gaagtagcga aacatgacat cactacgatc acagctgcaa gtacagatgc
    12241 aaaagcagca aaatatgtac aagagctgtt catgaataat tattttcgga tctataccaa
    12301 tcctgatgtg atcggtgtag agatgggggc agctttgaaa aatattattg ctattggtgc
    12361 tggcgctatt cacggcttag ggtttggcga taatgcaaag gcagcaatca tgacgcgcgg
    12421 attagctgag atcagccgtt taggtgtagc aatgggtgcc aacccgctga cctttatcgg
    12481 attaagcgga gtaggcgatc tagtcgttac ttgcacaagt gttcattcta ggaactggcg
    12541 cgcaggcaac ttgttaggac aagggcagcc cctagaagag gtgctagcca atatgggaat
    12601 ggtcgttgaa ggtgtgaata ctactcaagc agcgatggaa ctagcccaaa taatggaaat
    12661 cgaaatgccc atcactcaaa caatctatga agtgctgtat gaacaaaaag aaatcaaaac
    12721 agccgcaaaa gaaatcatgt tacgtgatgg gaaaaaagaa aatgaattct cattaacaat
    12781 tttttgaagg agcgaatgta tatgaaagtc aaaaaagcag ttattccagc ggcaggatta
    12841 ggaacaagat ttttaccagc aacaaaagct atggcaaagg aaatgttgcc aattgttgat
    12901 aaaccaacaa tccagttcat cgttgaagaa gcgttgaaat caggaatcga agacatcttg
    12961 atcgttacag gaaaagctaa acgaccaatc gaagatcact ttgattcaaa tattgaatta
    13021 gaaacaaacc taagtgaaaa aggaaagacc gaattattga aattagtaga agaaacgaca
    13081 gatgtcaact tgcatttcat ccgtcaatct catccaaagg gtttaggaca tgccgttctt
    13141 caagcaagag cctttattgg aaatgaaccg tttgtcgtta tgctaggcga tgatatcatg
    13201 gaagatgaag taccattgac acagcaatta atcgatgatt acgaacgtac tcatgcttct
    13261 acgatcgccg ttatgcaagt tcctcatgat gaaacttcaa aatacggaat tatcaatcca
    13321 ggagaagtat tggaagatgg gttatacaat gtcaaaaact ttgttgaaaa accagatcca
    13381 agcaaagcac caagtgattt agctattatt ggacgttact tattgactcc agaaattttt
    13441 gatgtattgt ccgagcaaca accaggagcc ggaaatgaaa tccaactaac tgacgcaatc
    13501 gatacattga ataaaacaca acgcgtattt gcccgtaaat tcacaggtaa acgttacgat
    13561 gtcggtgaca aatttggttt tatgaaaaca agtattgaat atggtctaac acatccagaa
    13621 gtaggtgcac ctttacgtga gtatatcctg tctttaggta aaaaattaga agcagaagga
    13681 agcaagatcg atcataatcc aaaaggaata acagaaatca aagaagaaaa gaaaaaataa
    13741 cccttttttc taacgagctt cagctgctaa ttgaataaaa agtagttgaa gctcgttttt
    13801 atttgtttaa aaaacacgaa aatgctatcc ttatagaaaa gagagacaag aagggagttt
    13861 gatcatgtca ggaggagaaa ttgcaggatt gatcgcagca atcgcctttg cgatacttgt
    13921 cgtttttatc gttcgtgtgt tgttgcaagt ttctaaaact ttagaaaaag tagatcagac
    13981 tgtagcagaa gcaaatacga cgatcgaaat cgtcacaaaa gacgtagatc ttttgtctag
    14041 acaagtagaa ggcttgctgg tcaaaagtaa tgaactgctc ttggatatca atggaaaagt
    14101 cgcaacgatc gatccattgt tcacagcagt tgctgattta agtgaaagtg tatcagaact
    14161 taatcattct agtaaaaaca tcgcgacgaa agtcggcgga atcggtaaaa cgacagctaa
    14221 agcgacggtt gccggaaaag tcggtgggac agcgatgaaa ttttttaaaa acaaaaaaca
    14281 tactgaaacg acaggaggaa aataaaaatg gctaaaaaag gtggattttt attaggtgca
    14341 gtagtcggag gaacagccgc agcaatcgcc gcgttattgt tagcaccaaa atctggtaaa
    14401 gaacttcggg atgaattagc tgcccaagcg gatgatttga tggatatggc ttcagattac
    14461 acagatatgg cgaaagaaaa atcgactgag ttaacaggta ttgcaaaaga aaaagcgcaa
    14521 gatctttctc aacaagcagg tgatctagca ggtagtgtca aacaaaaagt aagtgaatca
    14581 gcagatgaag caggaagtga atctgacgat atcttgttaa atcttaaaga acaatcagct
    14641 gacttatcta atcgtttcaa aaaaacggca gaagatatga aaaaacctgc agatgaatta
    14701 ggaagtattg ctaaagatac ttcagaagat atcatgattg atgtaaaaga cgctgctggt
    14761 aaagcaggag atactgtcaa tgaaggaatg tcagaagcaa aaccagttgc agatgacaca
    14821 aaagaaatga tgaaaatggc aaaagaagat gcgaaagaag ctaaaaaaga aataaaagat
    14881 acaatgacag attcatctac aaatcactaa aatcactaaa atcacaaatt tatagaataa
    14941 aaaggtggga gcggactagc tctcaccttt tttactctta tttttctaaa actagtaatt
    15001 cttttggtgt agtcgtgaat ggcacacagc catcgcttgt cacatataca cagtcttcga
    15061 tacgtacccc tactttttca ggaatataga ttcctggttc aagagagaag cacatccctt
    15121 cttcgattac taagtcattt ccttctacaa gggaagggaa ttcgtggacg gttgttccga
    15181 tcccgtgacc taaacggtga ttgaaatatt cgccgtagcc atagctgttg atcacgtttc
    15241 gtgcgatttg atcaagttca cctgctgtca cacctggacg gacggcttct tgtgcggcaa
    15301 gctgtgcttc aagagtgatg ttgtatattt tttcttggaa gtcggttggt ttttgataag
    15361 caattgtacg agtagcatca ctgcaatagc cattccaaac aacgccaaga tcgaataaca
    15421 caagttcatt cggtgaaatc ttcgtgtttc ctggtgtacc atgagggctt gcagcatttg
    15481 ctcctgcaag gactaatgtg tcgaaagaca tttgtgaaac accttgtttt ttcaattggt
    15541 attcgatttc tgcaatgatc gcttgttcag tcacgccttc tttcactgct ttaaagccaa
    15601 tctcaaatgc aacatcggcc catttaccag cttcgatcag tttgtctttt tcctctagag
    15661 ttttgatcag ttgtagacgt tggatgatgg aagctagatc agtgtaagaa tccgttcccg
    15721 tcaagatatc agagatagca tcgaagcgct cgacagtcaa ggcgttcttt tcaatcccta
    15781 cattgccagg ctgaccatag cgagcacgaa gttcttttcc gatgatctcc caagggtttt
    15841 cgctgtctaa atagccacgg acatcatacg cccaactact gttttgagca tcttcaactt
    15901 ccaaagcagg agtgaaaagg aaaggatctt gttcaagagg gataaaaaga gctagtacac
    15961 gctcatgagg atcactttcg tatccggaaa agtaagcgat gtggccaggg tcgctgatat
    16021 aagccaattc gacttggtgt tgtgccatcc attgacgtag ttcattgatt tttacgttat
    16081 tcatttggca acctactttc taaattaatt ttgtattcaa taattgtacc actgatttat
    16141 taaaagacca acgttctaaa aactgaaaaa agtaaaaatt ttcatgaaaa cagagataaa
    16201 acggttgcaa ttcttgagat tatttgatat tctattttag aaatgtaaga cgtattttca
    16261 gaaaacatat aaaatatgaa taggagaaca caaatggaaa agcaaacaat cactatctat
    16321 gatgtagcga gagaggcaaa tgtttcgatg gctactgttt cacgtgtcgt aaatggcaat
    16381 ccaaacgtca aaccagcaac aagaaaaaaa gtcttggaag ttatcgatcg cttggattat
    16441 cgtccaaacg cagttgcgcg tggcttggca agtaagaaaa caacaacagt tggggtaatc
    16501 atccctgatg tcagcaatat gttctttgct tctttagcac gtggtatcga tgatgtggca
    16561 acaatgtaca aatacaatat tatcttagca aattcagatg gtaacgacca aaaagaagtc
    16621 aatgtattga ataacttact ggctaagcaa gtggacggcg tgatcttcat gggtcaccat
    16681 atcacagacg aaatccgtgg agaattttca cgttcaaaaa ctcctgttgt attagctggc
    16741 tctattgatc cagatgaaca agtaggtagc gtaaacattg attatgtatc agcaacaaaa
    16801 gatgcagtaa acaaattggc aaaaagcggc aataaaaaaa tcgcttttgt cagtggtgcg
    16861 ttgatcgatc ctatcaatgg acaaaatcgt ctgaaaggct ataaagaagc attaagcgaa
    16921 aataacctac catatagcga aggattgatc tttgaagcac aatacaactt caaagatggt
    16981 ctatctctag tcgatcggat ccataatagc ggtgcaacag ctgtctatgt ttcagatgat
    17041 gaattagcca tcggtatttt ggatggttta ttagaccgtg gcgtgaaagt accggaagaa
    17101 ttcgaaatca tcacaagtaa caattcacta ctgacagaag tagctcgtcc tcgtttaaca
    17161 agtatcacac aaccattata cgatttaggg gcggtatcta tgcgcctatt gacgaaaatg
    17221 atgaataaag aagaagtcga agaaaaaacg attatcttgc cttatggaat cgaagaaaaa
    17281 ggatctacaa aataataaaa ggacaaccat tcagaggttg tgagcctgcc gtttaactct
    17341 gcgttacaag gagcaatttc aaaaaacagc atttcatgtt tgatgaatat tgtgactcgt
    17401 gattcggagt tggcaggaga acaccgttta ttcgggaaaa ggggttatga caaaattttg
    17461 tttaatcctt tttttttgtc ttaaaaaaga gagaaagtgg ttgaaattac atttatcgta
    17521 tataaaacaa tccgtgtata gatgctgcat tatgttcacc accatcaaaa aaataaggga
    17581 ctgtgacaat actattgtca cagtccctta ttactgtgta ttctattaaa tcaatcatct
    17641 ttctcatctg attctttggt tgcttgattc gctcttgcat aagctgaagc ggtgttccag
    17701 taatctgtat agttttcatc ggtaccgcca acgccaaatt taaaggcgct tttcttcggt
    17761 ccatttttcg cccatagcga ttcaactgtt tttcctggtg tttggatgga ttttttattg
    17821 acagtaactt ttccaggtgt ttgaccagta aatccagata cttttttctt catcacatca
    17881 gatgataatt cgaatttctc atcagtgcca aaaatgtcag gttttgcttg gtaagcttga
    17941 ttgatcagat tggcaagata attagccgaa cgtatccttg ctttgctgtc cattccagta
    18001 ttgtcatcgt gccctgccca gctactgatg gtaatagacg gagtagagac aattagccat
    18061 gaatctcggt attcattggt agaaccagtt tttccgaccc aatctgcttt tcctagattt
    18121 ccgtttaagc ttgagatggc atctttgaat ggtgtagtga tttttgcatt gatcacactg
    18181 cgcatcatgt cattcatgat cgatgccgtt gcttccgaat agatccggac agagttgctt
    18241 tcgtgtttat aaattacatt tcctgcgtta tctgtgatgg aatcgatgat atagccttct
    18301 tcatagacgc cgccgtttgc taaagcctga aatccattgg tctgttgaag cgtcgtgaca
    18361 tctactgtac ctaaaggagc agattcaacg ccccaattgt catttgccgg gtagttcatc
    18421 tttgccaagt agtgctcgta agcatattgt ttcgatccac cggaattcaa cacatcttga
    18481 tataagtgat aagccgggat attgttggac cattctagtg actcacggac ggtttggaag
    18541 gtgttcgatc cttcgttagt agcattgacg attttctcgc cagcattttc tccttcttgc
    18601 caagttgttg cataatctga tacacgggat tctgatccga taagccccat gtcgattgca
    18661 ggtccataaa caagaactgg tttgattgat gagccagctt gacgttctgt atcgaaggca
    18721 tggttatttt gattctgact gtaattccgt ccgccaacga atccgtagat gcggccagtt
    18781 ctgttatcca tcaatacatt tccggtttct acttgactgc cagcaccatc atctaacatg
    18841 tatccataat tttctacgcc attttgcaat gcagcataga catctttatc gattgtcgaa
    18901 tggattgtat atcctttatt ttggatcgtt tgctgtgcct tttgataata agcgtcactg
    18961 accgatgaat cagacatatc agcgttgtct ttttcagcca attgttgtgc aatgattctt
    19021 gttgcttcat tcatcacagt ataatacaag aattctctgt cagtctgttc tgcgatttgt
    19081 tgtggtagaa agtcttttgt aaggtcatag gcttttgctt cttcgtattg ttctttcgta
    19141 atttggcctt cacgatacat actgaataaa acaaaatctt ttctggcaag gccggcagaa
    19201 agatcttctt ttagcgcacc tgtgttcgtg tatggactat acgtgatcgg gctttggggt
    19261 aatccagcga tataagcagc ttgcggcagc gtcacatctt ttgcatctac accaaagatt
    19321 cctcttgcag cttcctggac tccagcaatg ttttgtccct tattattacg accaaatggt
    19381 gagacattca aatacgtagc aatgatctca tcttttgaaa agtatttttc tacttgtgca
    19441 gaaagaatga tctcgtttgc tttacgtttg aatgttgttt catctgtaag gatctgctgt
    19501 ttgactaatt gctgtgtcaa agttgatcca ccagaagagc caataccagt agcttcagat
    19561 actaatgctc gtaaaacagc tttaggaacg taaccttggt gtttatcgaa gtattcatcc
    19621 tctgtgctga taattgcagt tttcaataaa ggtgaaattt tatcagatga aatagtcgtg
    19681 cgcatcagat ctgtctggat ttttgatatc tctgtattat ctgcataaac aatctttgac
    19741 gtttctgtaa tgtttcctag ttctgtctgc agtgcttttt tagtcggcaa ttgtgtgtct
    19801 tcgacgagat aggcaaaata gccagcgcct attccaatac ctagagctgc gaacatcaaa
    19861 agaagaacag taataaaaac agtcaatgat tgaaaaactc taaaaataat cttaggaaca
    19921 aaccattttt ctttttttct tctattctgt ttttttcgag tatttttgcg tggcaaaagg
    19981 gtcacctcaa ctaatggttt tatttcgcta attatagcaa ataatagaac aaaaaaacag
    20041 acaaggctgt ttttggcagg aatttctttt ttaaaagagt taaaacgtga gaaaatgatc
    20101 ttttttataa aagagttctt aagcttttct ttagagaaaa tttcagttac tatggagaac
    20161 agggcaaaga aaaatcaatc attttctttg tatatcatct taccaatata taggaattgt
    20221 tagtaacaat tgcctttcaa ggaggaatcc atccatgtta ttaggctcac acgtcagcat
    20281 gagcggaaag aaaatgctgt taggagcagc agaagaagca gccagttatg gatcttcgac
    20341 ttttatgatc tatacaggcg cccctcaaaa cactagaaga aaagccatcg aagagatgaa
    20401 tattgatgcc ggaaaagcgt acatggcaga aaacggtcta acaaatatcg tcgttcatgc
    20461 cccttatatc attaatttgg ggaatacgat caaaccagaa atgtttcctt ttgccgtcca
    20521 atttctgaga gaagagattg ttcgtgcgga agctttaggc gctactcaaa ttacacttca
    20581 cccaggtgct catgtagggg caggaacaga agccggaatt gctagaatta ttgaaggctt
    20641 gaatgaagtt ttgacaaaag aacagacggc acaaatcgct ttggagacaa tggcaggtaa
    20701 aggtacggaa atcggtcgaa catttgagga attagcgcaa atcatcgatg gagtaaaatt
    20761 gaatgaaaaa ttatccgtta cttttgacac ctgtcatacg aatgatgccg gttataatat
    20821 taaagaagac ttttcaggtg taatggaaga gtttgataag atcatcgggt tagatcggct
    20881 taaagtactc catatcaatg attctaaaaa tccgcaaggt tcgcataaag accggcacgc
    20941 caatattggt tttggaacaa tcggattcga cacgctgaat aagatcgtcc atgatccaat
    21001 gtttgacaat atttcgaaaa tcttggaaac tccctatgtc ggcaaagata aaaagaaagc
    21061 ttacgcacca tatggaaaag aaatcgccat gttcaaagca caaatattcg atccagaagt
    21121 gtttcctgag ttattagcag aagaagtgat actctaagat tttctatctg acagcagcaa
    21181 aaaaggacca ggcacattgc cttgtccttt tttgtttaag aaacaaagga gtgctttttg
    21241 cagtcttttt catcatgcat cttctccccc ctctttttaa atttagacaa acagggtata
    21301 ctggtagaaa agtaaaaaaa cgaaaagttt cacaagcaag tggcaaaacg tgattggaag
    21361 gacgaaaaga tgctgaacac tttaaaaccc ttgatcaacc aactaaaaaa gaaacataca
    21421 tactttattc ttggcatagc cctattattt acaattattc gtttgtattt atatagtaaa
    21481 gcaatctatg gaacagacat gtcggcaacc tatgatgacc agctgctgat tcgctatgct
    21541 caaaatattt tggacggtaa atggctaggg gagtatacga ctacaacact ttccaaagga
    21601 atctcctaca gcttattttt agtacttgca cataaactgc atctttctta tgcagttttg
    21661 ttcggcatgt tcagtatttt tgccagtata ttggttgcac tcgcgtttaa accgatcgtg
    21721 aagaacaagt atcttctttt aagtttctat ttttattttt tgttttctcc gattagtttt
    21781 acacatgaat attccactcg aacgtatcgt aatgccctcg tgattccggc tgttgagatc
    21841 attatcgctt gtttactagc tatttattac cgtaaatata gttccagcaa aaaaatgctg
    21901 ccgtggtttt tagggctagc tgtttctttt cctttctttt ggttcattcg cgaagattcc
    21961 atctggcttc ttccttttac tgtagtcgcg ttaggcatca gtttcgtcca gatcttgcta
    22021 ggacaagact tttctttcaa agaagcaaag aagttaaaag aacgaccatt tctcctttcg
    22081 aaacaagaat ggctgaaact ttcattgttt ttactccctc tagtcggttt ctccatcgtc
    22141 tatcagtgga tcgaatataa aaacgagaca acatatagta ttgccgccat caatgaccgt
    22201 tcgagtggcg aatttggacg tttgatgaaa cagctgatcc gaatagatga cgaaacgaac
    22261 ttaaataaag aaaacagtga gatatgggtc tcgcatgctg cattaaataa agcattagac
    22321 gcatctccta catttcatgc tgtttctact cgtattgacg aattgtatac gactcatgcg
    22381 tggacccaag gtggaaaagt aaaagaatta ccaggagata tcattttttg ggcattgcga
    22441 gatgtggtaa gcgaatctgg ttattaccaa aacaatgcaa aagaaaccaa tgatttttgg
    22501 aaaaaagtca atcaagaatt agaagaagcc tatcaaaagg gaactatcaa aaagaaaaaa
    22561 gaattctatc tgatgggatc aggggatgga aagacgatga atgatctgcc aatcgtattt
    22621 gcttttctga aatcaggata tgcctatgca tggcgataca aagatttcca tcaagggggg
    22681 aattatagtt tcggtacgca agaacaagtc gaacaggccc aagaattatt gaatcttcca
    22741 ctaatggata attggatcga tagcagtgat ccgagaacac ctgatttcca gttgacaaaa
    22801 acagcaaaag tcgcgaatgt catgataaaa atttaccaag ttctggccat tcccgtgctg
    22861 attgcttcaa tagcagggat attacttatg atactaggaa ccgcatttgc aaaagctgat
    22921 cgtgcctatt atagttcctc tttgattgta gtcaccggat taatactgac acaattggtt
    22981 tttcttttcg gcgtctcgtg gttttgttct tatgcgccag aaaaaaagga ttatttttta
    23041 agtgtctaca ctggcgcagg cgtgccatta acgcaattca tcgtagtaac aagcatgcta
    23101 gttttcagta aattgaatct gaaaaaagct ttatcttcca aataaaaaca tactaagatt
    23161 agagg
//
LOCUS       DAFLWQ010000043        22639 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.044, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000043 DAFLWQ010000000
VERSION     DAFLWQ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.044"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(228..1115)
                     /locus_tag="L1V16_001662"
     CDS             complement(228..1115)
                     /locus_tag="L1V16_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1276005.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(1112..1981)
                     /locus_tag="L1V16_001663"
     CDS             complement(1112..1981)
                     /locus_tag="L1V16_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1276006.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(2118..3404)
                     /locus_tag="L1V16_001664"
     CDS             complement(2118..3404)
                     /locus_tag="L1V16_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1276007.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3677..4255
                     /locus_tag="L1V16_001665"
     CDS             3677..4255
                     /locus_tag="L1V16_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBN1276008.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            4255..5184
                     /locus_tag="L1V16_001666"
     CDS             4255..5184
                     /locus_tag="L1V16_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1276009.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            5181..6917
                     /locus_tag="L1V16_001667"
     CDS             5181..6917
                     /locus_tag="L1V16_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBN1276010.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(6980..7816)
                     /gene="pheA"
                     /locus_tag="L1V16_001668"
     CDS             complement(6980..7816)
                     /gene="pheA"
                     /locus_tag="L1V16_001668"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBN1276011.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(7813..8322)
                     /locus_tag="L1V16_001669"
     CDS             complement(7813..8322)
                     /locus_tag="L1V16_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBN1276012.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(8315..9610)
                     /gene="aroA"
                     /locus_tag="L1V16_001670"
     CDS             complement(8315..9610)
                     /gene="aroA"
                     /locus_tag="L1V16_001670"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBN1276013.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(9623..10714)
                     /locus_tag="L1V16_001671"
     CDS             complement(9623..10714)
                     /locus_tag="L1V16_001671"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBN1276014.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(10731..11897)
                     /gene="aroC"
                     /locus_tag="L1V16_001672"
     CDS             complement(10731..11897)
                     /gene="aroC"
                     /locus_tag="L1V16_001672"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBN1276015.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(11899..12963)
                     /gene="aroB"
                     /locus_tag="L1V16_001673"
     CDS             complement(11899..12963)
                     /gene="aroB"
                     /locus_tag="L1V16_001673"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBN1276016.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(12996..14018)
                     /gene="aroF"
                     /locus_tag="L1V16_001674"
     CDS             complement(12996..14018)
                     /gene="aroF"
                     /locus_tag="L1V16_001674"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBN1276017.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(14677..15651)
                     /locus_tag="L1V16_001675"
     CDS             complement(14677..15651)
                     /locus_tag="L1V16_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HBN1276018.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(15632..17515)
                     /locus_tag="L1V16_001676"
     CDS             complement(15632..17515)
                     /locus_tag="L1V16_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HBN1276019.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(17533..19758)
                     /locus_tag="L1V16_001677"
     CDS             complement(17533..19758)
                     /locus_tag="L1V16_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBN1276020.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            19873..20907
                     /locus_tag="L1V16_001678"
     CDS             19873..20907
                     /locus_tag="L1V16_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1276021.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(20974..21987)
                     /locus_tag="L1V16_001679"
     CDS             complement(20974..21987)
                     /locus_tag="L1V16_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1276022.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(22065..22253)
                     /locus_tag="L1V16_001680"
     CDS             complement(22065..22253)
                     /locus_tag="L1V16_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HBN1276023.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         6450 a         4863 c         4096 g         7230 t
ORIGIN      
        1 tgacaatcag gacagtcatc ggcaatatag cagcaatcac ttctttaaaa ttttttagca
       61 tgtatcctcc tcctttactc tttaagttta ccttaaaatg aaagagtttt cgagcacaaa
      121 cttaaaacgt tatcatttaa tttttctcaa cataaaataa cacacgtccc aaaagtatct
      181 ttttacttgg aaaaatgact ttgaaggaac gcgcttattg tgttttttta ttttacagag
      241 ccgatcattc cttgaacgaa ttgcttttgc aaaacaaaaa atacgatggc agttggtaaa
      301 gtagcgatga ctaatccagc catgatcatt ccatagtctg gtgtatagga agcacccata
      361 gcagataaaa caagcggaac cgtccgttta tcaggagatt gcaaagctac taagggccat
      421 aaataattgt tccagctact catgaatgtg atgattgcag ccgcggcata ggtattttta
      481 gccgtcggca tatacactct aaaaaaaata cttagttctt ttagaccgtc taatcgagcg
      541 gcttctacta gatcttttgg aaaagattta acattttgtc gaaagaagaa gatcaaaaaa
      601 gcagtgctaa cagatggcag gatgacaacc aagaaactgt tgattcccaa aaccgttccg
      661 ttcaattgtg aaaacattcg atataaaggg atcatcaatg ccgcaaaagg aaccatcatc
      721 gatagcagta gaatattgaa aattaggtct tttcgtttac tttgataaat ctcaaatcca
      781 tatcctgcca ttgacgaaat cagcaatgca aacacagtgg tcaccaaagc gatcatcgct
      841 gaattccaaa gggaacgagt aaaattcagc tcattggaaa acaaattttg aaaattgatg
      901 atcaagttac tgccaatctt tatttttccc gatgtgatat ccacgggtgt attcgtcatt
      961 cccaaaacca tccagacaaa agggaaaatg gaaataaatg ataggatgct taatgctgta
     1021 tactttaata ctgacccaat tgtcgaacga agttctaatg cttgtttttt gacgttgggg
     1081 cgttcgattg tttctttttc taccatattt ttcatcgact ttctcctcct actttcgttt
     1141 ggattatcga caatatcaca ataaaggaaa caataacaaa ggaaactgct gccgcatatc
     1201 caaaattagg cgtgaattta taactcaaat tatagatgta ttgagatagg gtggtcgttg
     1261 catttgctgg tcccccgcca gtaatatttt gtacttcatc aaaaagctgc aatgtcccga
     1321 tcgtcgaagt aatggaagta aacaaaatga ttggttttaa atttgggatc gtcactttga
     1381 taaactgctg ccatttagaa gcaccgtcaa tagatgctgc ttcataaatc tccgaatcaa
     1441 tattttgcat gcctgaaagg aaaaaaatca tattgtatcc agtccaacgc caagtgatcg
     1501 aaagaatgat cagaactctc gcccaaattg gatgagtcaa ccagccaatc ggtgtgtcaa
     1561 tcataccaat gcccaacaac aagttgttta caaggccaga ttgagaaaat agacttttca
     1621 tgatcagaga ataactgacc atcgaagtga tacatggaag aaagatagcg gttcgaaaca
     1681 accctttata tttcaacttt ttatcattta aaaggttgga aataaaaagt gctagaaaca
     1741 acatgatcgg tacttgtaca agtaaataca ggaatgtatt aaaaaaagct tttttaaaag
     1801 ttgcatctgt caacatccgc tgataattac ctaacccgtt aaatgtcata ttgacagggg
     1861 gaccactttg aaaagacgtg atcaaagcca aaaccatcgg aataaaaacc atgattgata
     1921 tcaaaatgac tggcaagatt aaaaaagcat gcccgttttt gaataaatct ttctgcttca
     1981 ttcttttccc tccaattcta tcattgatta tctacatgaa aagacaagaa agacaatatc
     2041 tgtaaggcag acgtgatctt ttttgtcttt tcgtttgtct gatgaaaaag cgaagaaatt
     2101 cactttttta ccaccgatca attagccaat tgtgcttcta cttgtttttg tgtatctgct
     2161 agtaccttgt ctgtctcttc tccattgatg attcgatgaa gagcttcagc tacgactgct
     2221 tcaattgcat aggtctcatg tccgtaattc acttctggta tttcagatgt ccatgttgaa
     2281 aaatcgtcaa agatcttttg accactgtaa aattcagaag cttcttgata agcttcttgt
     2341 tcattcgcgc taagcatcgt agatactagt ccgatttctt tcgcaagagt gcccatcagt
     2401 tcttcattcg aagcaaacgt tgcttctagg aaatctttcg ctgaatcttc tccagctact
     2461 cctttgatca cataccagcc agcgccgcca aggttagaag cttgcgcttt ttgcagattt
     2521 tctggaagtg caggtattgg tgcaatcttc cattttccag attggttttc tgctccttgg
     2581 atcgttgaag aataccaagc gccagttggg ctagaagcta ctgctcctga ttgtatcgca
     2641 gttactccag cattccagtc agaggtttgt tcgactagat cttctttcaa aagagtggca
     2701 aacaattcaa gaccatactt taaagatgca ttgtcttgga tcgtgactgt ctccccatct
     2761 tcagatgtat accattctcc tgcctgttgc ataatcatcc ttactcgacc aaggtcagaa
     2821 ggattgactt cagcgatttt ctttcccgtc ttttctttga catctcgcgc tacttgaata
     2881 tactcgtccc acttcagatt ctccatatcc tcttctgtat aacctgcttc tgccatcaga
     2941 tccgtacgat agaagtttgc tgttacgccc gaatcgaaag gaacaccgta tattttatct
     3001 cctactttgt ttaccgcaaa tttatacggt gcaaaatgat cttcctttac aatagcagac
     3061 aaattagcga atgcatctgg ataagaagtc aaatagcctt gtatcctata atcttcaatc
     3121 aagacgatat tgggcaatcc ttctgtattc ccgctcgcta aagcggtgtt cagtttctga
     3181 acgatatcat cctgagacat cgtaacaact tctatctctg tttcttcgtt ctcataaact
     3241 ttttttgctt cattcactgc tttgatattg aatgtctcat cccacgccca gacagtgact
     3301 ttttcttctt tgtctgctgt actactagca cttccgcatc ctgttaagaa acctgatgct
     3361 gccgctaaac aaacgactcc agcaattaac tttctgatgt tcatttttat ccgctccttt
     3421 tccatccatt agttgtttac gtttgctaca ttcatcatac caaaatttga aaacggtttc
     3481 tttattattc agatacttca aaaatttctc ctaaaataat aaaaaaatac aaatcaacta
     3541 tgacaaaagg aataatctta gcatctagac caaagatcga aatggtgagg tttctttaaa
     3601 ataaaaatat ccttgcattt tctcctagaa ataagtattt ttaaattaca agactattct
     3661 taaggcgggt aaaaaaatgc caatacgcgt aattcttatc gatgatgaac agacgatttt
     3721 agatggaatg aaacagttga tcaattggtc tgagcacggg tttcaattaa tagggacttt
     3781 ttccagtccg ctgaaagcgc ttgatttttc tttggtacat gcaatcgata tcgtggtcac
     3841 agatgtaatg atgcctgaat taaatggaat cgaattatcg cggctattaa aacagcaaca
     3901 acctgaaaca cagatcctta tcctctctag ctatgatgaa tttgatatgg ttaaagattc
     3961 ttttaaagaa ggcgtcgctg attatctttt aaagcctcga ttgagtcctg atttttttct
     4021 aaattcctta actgccgttt cacaaaaaat caaaaaaaag cccaacaaaa gcccaatcac
     4081 caatcgttat gagcagatct gcgagaatct ttcacagcag attgctggac aaactcgtcc
     4141 attgcttgac cctcttcttt ttgaacacac cttgtttttc tgttatatac cgaaaaacgg
     4201 ccattcagtt caaaacaagg ctctaaacaa aaacagtcga tcacccattc attgatggat
     4261 agcgacgatt cgtttactat ttatcctgtt tctacctttt cggaagaatc cggctatgta
     4321 atcaatactg attccaaaga tacacttagg aagtttgttc aaaagtttcg tcaagaagtt
     4381 tttccaggtg atttttttgt tgtttctgat tcttttgcaa tccaagatat caatgaaata
     4441 ttccaagaga tcagaaattg caccaaagga caacgtttct atcataaggg aaagaacctt
     4501 gcttatcagc atgaacttct tccgttatta accaaccacg agcagcaagc aagtagttat
     4561 ttaacaaaaa tcgttcataa agactacgct ttagctgtca aagaacttga gaatttcttc
     4621 acgacgatat tggaacagcc tattgatcca gcttatttga aacatgaggc aatcaatcgt
     4681 ttctatgcat tactcaacgc tttggctgac gagcatgttg ggaatgaaga actttctttg
     4741 ctcaagatcg cccttccttc tttattagcc gatgctgagt atttcgaaga tttttctatt
     4801 cttgtcaaag aaacacttga gaaactcacc cacttttctg caaatgcaaa aaaagacaat
     4861 ttcgatatct tgactttgat ctacgagttc gtccaggaaa attatgagaa agaaatcaat
     4921 ttacaacttt tatccgaaaa atatcatttt tcatatagct atctctcagc catctttact
     4981 gaaaaatttg gtatcaactt ttcaaaatat ctaaaaaaag tccgtatcag taaagccaag
     5041 ctctttttga cggaaacacg gcttactttg acggaaatct gtgagaaagt cggctatacc
     5101 gaactgggtt atttctccag agtttttaaa gaagagacag gaatgacacc ttctcaatac
     5161 cgtaaaggaa cttttgtaaa atgagaaaaa aaatcaaaga gcatgaactc tttgccaaac
     5221 ttctgttcat tttgttcatc ggtctttttc tgcaagccat cgtcatttct ttgtttattt
     5281 atcatcgatc aagggatgcc tatatccagc tgttcaatca atcgaatgat gtggtactaa
     5341 aaaagattca atctgaattt gaaagtttga atgatacaat cgagaataca ttagccgctt
     5401 ttgattctaa tccagctgtc aaaagctatt tttccaatga tccagcccaa catatggaac
     5461 agcttcagca actaagaaca atccaaaaaa tgaatgactc tctttcaaaa atccatccaa
     5521 tgatcgatta cgatgtattg atctttggag aaaatggaag aacttttgtc ggaaacgaca
     5581 tgctcactgc cgtatctgcc gattcttttt ttcaatctgc gattgctcag agagtgaatg
     5641 aacgtgctgc tgatacacaa atgctttttg cacaccacgg attgactctt cgcgataaga
     5701 aagcacccag cgtcttcttt gtcaaaaaac tgaaaaatac attgaatcac gtttacggat
     5761 atgctgtttt atcgatctca tccaagcaac tagcgaatct ttttcaatct gtagtaaatc
     5821 ctgagatatc gaagatctcc ttcatgaacg aagaacagac gatcatcgca tcaaatgaag
     5881 aaaatacaat tgggagccga tcaatgattt tcaaaaaact aacagtaggt gaaacaacga
     5941 tttcaaatgg acagcagttg acccgtcttc ctctgtaccg ccaggattgt acattactca
     6001 gtcaagtcga tcttcattct ttatctaacc aaatgggcgt gatttttccg attattttgt
     6061 ataatatcgt gacacttgct tttgctggct cattggtatt tatgtatttg gatcgacaca
     6121 caaaatcgat ctaccgcttg attgattcgc taaaacggct agaggaagat ggcttaaaag
     6181 ctactgttcc tgtacaagga agccatgaag tccaattgct agggaatacg atcaatcaat
     6241 tgctaagtaa tgctcagcat cattatgaac agacgatcca agacgaaaag aagaaacgtt
     6301 cgcttgaaat ccaaactatg caagcacaga tacagcccca ttttatttat aatacgctga
     6361 ctagcttgaa atttttgatt tggcagaaaa aaacagatga agcagttcaa ggaatcgaca
     6421 gtttcattac tttactaaga agtacgattg ggaaaaaaga agaagtgatt ccagtcaagg
     6481 aagaaatcaa aagcgtacaa agttacatcg atcttttgag tatgcgatat ggcgaaagaa
     6541 tctcggctaa aataatgatt cctgatgaac tgcagtcatt atctatgccg aatatgatcc
     6601 ttcaaccaat tatcgaaaac gcctatcttc atgcttttca caataaaacg caaggattca
     6661 tcacggtgta cggcaaaaca aaaaatcagc ttcttttatt cgaagtgatt gataacggcg
     6721 atggcttcga tactgaaaat accaaacaaa aaaatgatca tttttcagga atcggcatca
     6781 gccatgtaga tgagcggata cgcctaatgt atggcgatgc atatggctta acgatccaat
     6841 cagtgattgg gacaggaacg actgtaacga tttgtctacc gcttcttcct aaaaatcaat
     6901 cagaatatca aaaataaaga atagccaagc gctgattttt ttattttaag ttaaataaat
     6961 caatcagtat tcttgacttt catctacgcg tctcttctac tgtcagcact ggataacagc
     7021 ccaatatttg actttctcct ccgagcatct tgatttcttg gagcgcattc tctactaatg
     7081 tcattggacg gtccaacaac aaatcgatca cgaaaaaata ttctcccaag ctagttttca
     7141 atggtcggga ttcaatctta cttaagttga tttcccgcca gccaaaagct gccagcattt
     7201 tatgaagcat ccctggccga ttagcaggta gtgtcaagat gacactcatt tttactggag
     7261 ctgactgctg gctggtcatc tttcggtcac cgacgatcca aaaacgtgtc tggttcaact
     7321 cattatcttg gatattctca gctaagatct ccaatccaac atgctgtgct gtttctaatg
     7381 aagcaatcgc tgctgcgtct tctttcggat gttctgctac atacattgct gcagcagttg
     7441 ttgattctgt tgctactaaa ggaacattag gataatgcgt ttctaaaaac tgttgtgatt
     7501 gtgctagtgc ttgtggatgt gaaaggattt ttgtaatctt tgttgctgga ttgcctaaaa
     7561 gctgctgctt gataggaaga acgatttcac ttttaacttc gacttctgga tgtttggaaa
     7621 gaagatcgat tgtgtgatga acagctcctt ccaatgaatt ctctacagga acgacagcca
     7681 gatcgacttg tttgcgaaac aaagcgcgca aacaaacagg gatggaagca tacgcagtca
     7741 attgttctgt aggaaatagc tgacaagccg cctgataagt gaatgaactt tctggcccta
     7801 gatagctgac gttcatatgc ttttgatcct ttctataatg gtatcgatga tcttttctgg
     7861 tgtttgattg gtcgtgttga ttcgatgtgt cgcactttct tcataccaag aaagtcgttg
     7921 tgccaataat gcttttattt cttctcttgt ttttccaaga gctaaaggtc gaatagacgt
     7981 ttcatcttgt tggatacgat caactagaca gtccgcttct gcctctaagt aaagaacaat
     8041 cggctgtgtt tttaaaaaac gccgattttc tgcactttgg acaatccctc caccagtcgc
     8101 gataattttg tcttcatttg acagctttct taaaatatct gactccactt ttcgaaagct
     8161 tttttcaccg taatagtgaa aatattcggc aatcgacaat tggatatgtt cctcaatctt
     8221 tgtatctaaa tctacatact ctttttgtaa acattgagct aaccctttac cgattgttgt
     8281 ttttccagcg cccatgaaac caatcagcaa aatgctagcc atgagcttct cctcctgaca
     8341 caagttctgc taaatcgtca aaaaatgccg gataagagat tgaaacagct tcagctcctt
     8401 ctagttcgca aggtccatca gctatcaaag cagctacttg cagcatcata ccgattcgat
     8461 gatcgcctct gctggacact tttgcgccat gcagaggtgt cggcccatgg atgatcagac
     8521 cgtctgctgt cgcttttatc tttgctccca ttttctgtaa ttcttctgcc accgcatcaa
     8581 ttctgttggt ttcttttact tttaattctt ctgcgtcttt gatgatcgtg attccttctg
     8641 cttgagtagc cactaaagct agaatgggca attcatcaat cagacgcgga atgatttctc
     8701 caccaatcgt tgctttcttc aaatgactcg tcttgacact taaatcagcc gattggttct
     8761 gttcattgtg attcgtctgg gtaatcgctg cgcccatctc ctccaacaca tctaagatac
     8821 cagttcttgt tggattgacc ccgacatttt ttaacaacag ttggctttcc ggaacaagaa
     8881 gtcctgctgc tagaaagaaa gcagctgatg aaatatcacc tggaacagtt atctgttgac
     8941 cagttaattt ttgcggtccg gtcactatga tcgttttatc ttccactgtg atccttccgc
     9001 caaattgacg aatcatttct tccgtatggt tacgggaacg ttctttttca acgattacgg
     9061 atgtgccttc tgcttgtaat gccgcaaaca gcaaagcaga tttgacttgc gcactggcta
     9121 caggcatatt gtatcggata ggtgataaag agcgggttcc tgtcacagtg attggtagat
     9181 actggtcatt ttcttctcct tgcaagtcag cgcccatctc gcgtaaaggt tccatcactc
     9241 gccccattgg acgtttagac aacgaagcat ccccgaacag agtagtcgta aaaggctgtc
     9301 cagccaaaat acccatcaat aaacgtatgg tcgtaccgga gtttcccatg tcaattgatt
     9361 cggttggttg gacaaatgag tggctaccgc gaccatgaat cttgatcacc tcttcctctt
     9421 cttcgatctc gacacctaat tgttggaagg catgtaaagt actcagacaa tcttctgcgc
     9481 gcaaaaaatt ttgtatagtc gtcgttcctt cagcaattgc tccaaacatg atgctgcgat
     9541 gggaaattga tttatctgct ggtatcctaa cagtccctct taatccatgt atttgttgta
     9601 ataattgcat ttatccagcc tcctatttga tccagcaatg ataactggta ttagacataa
     9661 tgattctttt tgcttgtaac aaatcctgtt ggtttttaaa actgatttgc agtattccta
     9721 aaatatcttc cctggtctct tggatcttca aattaatcaa agaaactccc gcttttccga
     9781 tcagtccagt tacttctgca ataacgccag gttcatctgg cacatcgata aataaatcaa
     9841 aaaaggcagg aatcgcgcct tgcttatgga caggcaactg gtctcgactt tcttttgccc
     9901 gattgaaaaa agaaaagatt tccgattggt tctcagtcat gatccattct gctatttgtg
     9961 tcatttcttg ttgccaatct gccaatcgtt ccaataatat ctgcttattg ctcaacaaaa
    10021 tatctgtcca catgacagga tctgaggaag cgatcctagt gatatctcga aagcctcctg
    10081 ctgccagttg tttggctcgc ggatactctt gattgaattg ttctgcctga ttgactaagc
    10141 cagctgccag aatatgtgga aaatgactta gcattcctgt tatacggtca tgttctcttg
    10201 ctgtaagagt tacatatttt gctttggttc cgcaaaatag ttcttgcagt ttttcaacat
    10261 cttttttcgt cttttccaaa ggtgtaaaga tgtaataggc attttcaaat agtttagcat
    10321 ctgctgcctg tatacctgat ttatgagaac cagccattgg atgtccaccg acaaaccgaa
    10381 gatttttctg ctcagcggat gtcacgactt gctgcttcgt actgctgaca tccgtaatga
    10441 tgacgtgatc agacaagttg attctttcaa ggacatcaag ataagctaag gttgtacgga
    10501 cgggaacggc taataagata acgtctgctt gttctgcacc tgtttcaaaa tcacttgcaa
    10561 cgtaatcaac gatctgctgt tctactgctt gctcacgggt ttttgactga ctatcccaac
    10621 caactactat cagttctgga ttggtctgac gaatacaaag tgccatagaa gcaccaatca
    10681 gtccaagccc cacgataaaa acatgttgtg ccatcttatt tgcccccttt ttagtaatgt
    10741 ttcaagtagt cacggtactc cttcactgca gctttcaact caacaagcga atcacttggg
    10801 aattttgaca atagctctgt cgctaccaca gtggctacaa cattttccgc aacgacgcta
    10861 gctgcaggaa ctgctgtact atccgaacgt tctacacttg ctttgtaagg ttcttttgta
    10921 tcgatatcaa cactttgaag tggcttgtac aatgtaggaa tgggtttcat gaccccgcga
    10981 atgacaagtg gttcgccatt ggtcattccg ccttcgaagc cgcctagatt attggtacgt
    11041 cggaaatagc ctctttcttc ttcccatagg atctcatcca tcacttctga gcctggtaat
    11101 gaaccagaag tgaatccgac cccaaattct acgcctttaa aggcattgat actaaccaca
    11161 gcttgtgcga ttttggcatc tagcttcgtg tcccattgta cgtagcttcc taatccagct
    11221 ggaacgcctc caacgagcac ttctacaatt cctccgatcg tatctccatt tttctttgtc
    11281 tgatcgatca aatcttttat tctttgctca actgctggat caacaactcg tacttctgac
    11341 gcttcagaaa tttctttgat ttcttgaatc gagatatttc caggtatttc tgcttggatt
    11401 ccaccaagac aaatcacgtg tcctgctacg atgatgtcaa gttcttccag aattttcttg
    11461 gcaattgcgc cgattgctac acgcatggtc gtctctcttg cagaggaccg ttcaagcaca
    11521 ttccgaagat ctcgatgatg gtatttcata ccgcctacca aatccgcgtg tcctggacgc
    11581 ggacgtgcaa ctcgccgcag tgattggtct ttttcaggca cttctgctac agacatgaca
    11641 gttgtccaat ttttccaatc tttattttct accactaaag tgacaggtga accaattgtt
    11701 ttgccgtgac ggatgccaga cgtgatccga acacgatctt tttcgatctt catccttcct
    11761 cctctgccgt aaccagcttg tctgcgagcg agttcgtgat tgatttcttc ttctgacaga
    11821 ggtaatcctg ctggtagtcc ttcaataatg gctgttaatt ctggtccatg ggattctccc
    11881 gcagtcatat aacgcatctt acagtcctcc taagtaatct ttgaatgtct ctgtgggaac
    11941 aggaacgatt tttgcttgcc caatcttttc tagcaagatg atattcaatt ggcttcctct
    12001 tgctttctta tcatgggtta tcgcgtggaa taattcatct ggatgactta gatcgtacgt
    12061 aatcggcaga tggaattttt gaagtatcct ttctaaagca gctgtcgatc cagttggaga
    12121 caagccgatt ttttctgcat gagaagtgat ggctaccatt ccaatagcta ctccttctcc
    12181 atgactgact accccatatc ctgctgtatt ttcaattgca tggccaattg tatgaccaaa
    12241 atttaaaata agtcgatttc cttggtcaaa gacatcttct tccactactt ttcgtttgat
    12301 ttccaacgta gcagtaatga ttggaacagc atgttccaga agatcttttt cgtctttcag
    12361 ctcgttcagc tgtttccaaa gcgttgcatc tgctatagct gctgatttga tgatttcagc
    12421 gattccttct cgtaaacgac gtaccggcaa agtttttaga acctcaggat caatcaatac
    12481 accagctggc tggctaaatg ttccgacaag gtttttcgct ttgtttgtat tgactgctgt
    12541 cttcccgcca atactagaat ctacttgtgc aagtagcgta gtcggaattt gaacgaaatg
    12601 gatcccacgc atgaacgtcg aggccacgaa tgctgctaga tcacccacca ttcctccacc
    12661 aagtgcaagt atcccatcgc tgcgggtaaa atcattatct gctaaaaaat cgtataactc
    12721 agctgcttgt tctaaagatt tactggtctc acccgccggt acgattgaaa ggactggttc
    12781 aaaattagct tgtctcaatt ggaacatgat tttttctgca tatagtggag caacgtttgt
    12841 atcagtgatc acagctactt tttgaggtct ccaaatcgtt tgaagccatg atccagcctg
    12901 ttctagtgcg cctttttcaa tatgaatatc gtatttttgg ttatcaacat gtacagtaag
    12961 cattcgtttc acttctttct tttaaaaagc tggaattaat cgagtgtctg aatcttttcc
    13021 attgcttctt tcatgatcgc aacttctttc atcatgcgtg agtaagtctt ttcattcaac
    13081 gattggggac cgtctgacca agcatttgca ggatcaggat ggatctctac gatcatgcca
    13141 tctgctccgc ttgccacacc cgcacgagcc attggtggta caagttccca aattcctgta
    13201 ccatgacttg gatcaacaat cacagggaaa tgagttaatt ttttcatcaa tgggacagca
    13261 cttaaatcaa acgtattacg tgtcgctgtt tcgtaagtcc gaatcccacg ttcgataaaa
    13321 atgacaggag atttgtcttc gactgcaatg tattctgcag cattaagcca ttcattgatc
    13381 gtaccggaaa ttccacgttt caatccaaca ggtttacctg ttttaccgac agcagatagc
    13441 agtttaaaat tttgcatatt acgtgcgcca atctgtagga tatcgctgta ctcagccacc
    13501 atatcgatat gcccttcatc catcacttca gtaatcactt tcattccaaa ttcatcagcc
    13561 gcttgacgga tgtatttcaa tccttcttct tctaaacctt ggaaagcata tggagaagta
    13621 cgtggtttga aggcaccacc tcgcagaatt tttgcgcccc cggctttggc cattcgcgca
    13681 cattctctga tttggtctaa tccttcgata gaacaaggac cagccatcgt cacgaaactg
    13741 ccgtcaccaa tttttactcc gtctacatcc acgactgtat tgccaggatg gaattctcga
    13801 gaagtcaatt tgtatgtgtt taaaatacgc acagcatttt ctactccttc atagcgtgta
    13861 aatgctcctt cttgtaaact tcgcgtatca ccttttagtc caatcactac tcgttctgtt
    13921 ccttgatcga ttgagacttt gaatccttct ttttcgatat gatcgacgac tttttttatt
    13981 tgttcttccg ttgcttcttt tttcataatt actatcattg tttttcccgc tttcttttgt
    14041 ttacttatct atcttggctg attttctcta ctttttcaag gtggttttac attaattcct
    14101 actaaatgac cgtgtcctgt tgttctcatt ttcgctcctt ctttcctact tatgacccag
    14161 ataatcaaca aaaaaagatg tccctgtagg aaattgcctc tacagtgaac atcttcaacg
    14221 agccttaaaa agcgctgcaa aaatataaaa tagccactat agatgaattt ctctacgtgg
    14281 ctgtaagtcg tgtttaaaaa tctttagcca tcatagatac aaacctggtt tgtttgtacc
    14341 cacgaagtca tgaatacaaa cctatctaaa atagctaaag taatacgtat tcagttttgt
    14401 aagttttcta gatttcataa aaaatcgctc caaactgatg taagaattgt acctagtata
    14461 gacataaaaa aatcgactgt caatcatttt tatgaaactt tttttaattt tctgatagtt
    14521 aactttgttt ttcagaaaaa taacaattgg ttttattgaa gaaaatagtc atgaacaaaa
    14581 gtatctgaga acttttttac tctcttgttc atgacatata gaataaagca gctttgtctt
    14641 gtaaactccg tttttcaaat aataatctaa agattgctac tgaataataa agccgatttc
    14701 atggtcctct tcgctgctga ttcggtaagg tgactcaaca tccgctcccc agctattgat
    14761 acccccgact cctcttactt ttgcaaaaat cgtaagaacc gttcgtcttt ctggcggtag
    14821 ttcttctata tgtgttgcct gttccagttc ttctgctttg aatggtaaag cggaaaaagc
    14881 aaatggcgta tcctgctgtt caaatcgcaa cgaaaaatct tcttgatctt tatccgtatt
    14941 atccaacgtt tgatttcttg ttagttctac ccatttcgtt tccatatgca tgccgcattc
    15001 ttggggaaca aggtatgggg aaacggggag tcctgccact ttataaatac cttcgacacc
    15061 accagccatc cgatccggat atgtttcccc tgataggcct tcatactcaa aaaattttgc
    15121 tttcgttggc ataatgaacc ttaaacccaa tgcgggtaat tccggtaatc ctttttgtcc
    15181 ataataatgc atattgacaa gcattttacc ctctccagcg atttggtagg aaattgtcac
    15241 ttgggttttt ggtactgtgt tgatttccag tgtaaaaatg atttcaaccg tttcagcgta
    15301 ttcattactt gaatattgat tatttactgg agcaatcggc aaatcgatct ttttattgtc
    15361 caccagtact tctatttctt tgacttttgg atacaatccg gctcctaacc acataccgga
    15421 tttaaatcca aatccgctac ctctgtcatt atcggtcgtt gctcgccaaa aaactggaag
    15481 tgtttcccgg tatagccatt cttttccgtt tttattgagc gattccagtc cgcctcttgt
    15541 ataagaaaaa atataatgcg tattccccga tttgacacct aatgtacagt cgccgaagac
    15601 gattgcaact ttttccgtat ccatatgact tttatttact gtatttttca taataatatc
    15661 ttacctcctg catggcgggt ttttcttgtc catctgcaaa aacgatccca ttccctgaga
    15721 attcatagtc acttggttta tcgtcaaagt caccgccata gcgcatcact tctctgcctg
    15781 tgattggatc agtcacttgg atcgcctgat ctttaaaatc ccatatatag cctccttggt
    15841 acatttcata acgatcaagc aacgtcatgt aagaatccat tccacctaac gaattcccca
    15901 tgtcatgcat atattcacat aagatgaacg gtttttccgc tttattttca aggtagtcaa
    15961 tgatctcttc tggtggcgca tacatgcagc tttttacatc tgaaatcgaa tcttcgaatg
    16021 ctggatttgg aaaattccct tcataatgga caagtcgatc ggggtctact tttttgaagt
    16081 aatcgttcat ttgtcgaatg ttttcttccg cataagattc atttccaaga gaccaaaaaa
    16141 gaatacttgg atggtttttt aatgtttcga aattcgtttt tgctcgatca agaacagccg
    16201 cctgccactg aggtactgca cctggtacgt tgtaagaagg ctcaaatgcg cccatttttt
    16261 gccatgagcc atgggattcg aggttcgttt ccgccatcac atggattcct gcttggtcgc
    16321 ataaataata ccaagtgatc tggttggggt aatgagatgt ccgtacgccg ttgatctttg
    16381 cattttttat gatagccaaa tctttttcca tatcttctat agtgatggcg cgtccttttt
    16441 tcggatgcca ctcatgtcga tttaccccgt tgataatcat ccgttttcca ttgaagtaga
    16501 tgattttatc tttgatttcg attttacgaa aaccgaagga atagtcaata tactccgtta
    16561 ctcttttttc ttcgtctatc gtctccaatt caagcttata taaattgggc tgaaaatgcc
    16621 cccacagtgc cacattttca aatccatcga tgcgaatcgt catttgctct tttaacggat
    16681 attgctgttg atagatttcc ttcccatcag gatctagtat cgctacattc agctgactgt
    16741 ttttggctac ttgctcaaaa gacaaatcta cttcaagttt gccattttga catttgtcat
    16801 ctaagcgagg tttgatccaa agatcttcta aatggttttg tcctcgagca actaagaaga
    16861 catctctgaa gatcccaaaa aatcggaaaa agtcctgatc ttccaagaat gcagctgtac
    16921 ttcttttgta aacctccaca gctagaatat tttcttcttc caaataaggt gttaaatcaa
    16981 attcagacgg agtgaacgaa tcttcggcat acccgataaa atgaccattc aaccaaataa
    17041 acattgcttg ttctacacca gcaaaatgaa tcgagatttg ttttcccttt agaccttctt
    17101 ctaatcgaaa agtcgtcaaa tacgaaccaa ccggattgtc tttagcagct gaaaagatcc
    17161 cttccgcctc tttctcaggg cttgtcgtga aagggggacg gcgaaataca tgtccctccc
    17221 acggatacat cgtattgatg taatggatct tgtcataatt tgctaattca atatgactag
    17281 gaacagtgat ttcatcaaaa gaacaggcat caaaatcttt tttataaaat gtttttggtc
    17341 gtaccgaagg atttggcgaa taacaaaaac gccatgatcc atttaaagac tgtttaaggg
    17401 aggatgtggt ttctacttct tcccttgttg cataacaaac atgatcgcta tgtgcatttg
    17461 attggttcac tctaaaaact tgtggatcat ctaaccattt tatatttgct ttcatacttt
    17521 tttccttctc tctcataact ttttgaaatg aagcagttct gtttggaaat caccttgaaa
    17581 atcggggaag taaagtccaa ctgtcatcaa ttcggccccc gaaaatatcc gcttcgaggt
    17641 ctgttcctga taaagtgcct catcatctaa ccccatcaga tatacttcat ggaacgctgg
    17701 ttgagctgaa gctagtatcc tccctaaaaa cacaatagct tcatcttgtt taggagacac
    17761 aaacatccat gcggcaatat tttcttcaaa aggactcgcc aaacgataat aatggccata
    17821 ctggatcacc ggacgaatcg tttgatagga tataatttgg tcttttactt gctttttttc
    17881 ttcaggagac agctttgtca aatccagttc ataaccaaaa acagcgctca tagctgtttc
    17941 tcctcttgtt ttcaacgaag tagatctgtc ggtctgatga tttggtacag ctgatacatg
    18001 agctgtgatg gacgaaatcg gataagcaag gcttgttcca tattggattt tcatacgctc
    18061 cactgcatcc gtgttatcac ttgtccatga ctgcggcata taataaataa acccggcatc
    18121 aaaccgtcca cctccaccag aacagccttc ccataagatt tccggataat cagttgtcaa
    18181 atgttcaagt agttcataaa gcccgagcat ataacgatgc gctacttctc cttgtctctg
    18241 tgggtcaagg gtaatcgaat agacatctga aagcgaacgg ttcatatccc atttgatgta
    18301 gtcaagagga atcgtatcta aaatctttct catttgtttc tcaatcgtct gccgaacatc
    18361 taaccttgta aaatccagta catgttgtga tctggaagca gaaggcattc tacctggctc
    18421 ctgcataaga aaatcaggat gtgttcgata cagttcagaa tcaaccgaga tcatttcagg
    18481 ttcaaaccat aaaccaaatt tcaatccttt gctatgagca taatctgcta tttcacgtaa
    18541 tccatttgtc aacttgcctt catactcgaa ccagtctcct aatgaagaat tgtccgcatc
    18601 tctttttcca aaccagccat catctaatac gaacatttcg atgcctagct cctttgcttc
    18661 atcaatgatc gccttgattt tttcactatt gaagtcaaag taagtggctt cccagttatt
    18721 gaccagaatc ggccgttcag caaattgatg acgacctctt gcgattcttt cacgtagcaa
    18781 ctcatggtgg atctgactca ttttgttcaa tccctgactt gagtaagaaa ggatcatttc
    18841 aggtgtttga aaagactggc ctgcattcaa ttcccacgaa aaacgatggc tgttgatccc
    18901 accgacgact ctcaattgat tgatctgatc tttttcaagt tcgaaagaat ggttgccgga
    18961 ataaacaaat tgaagtccga tcgcttctcc agtattttct gtcgtatgat gatgaactaa
    19021 agcaataaag ttattcatat ggtgactgct cgttcctcga cggctttcaa atacttttgt
    19081 tccagataaa acagattgcc gtgaaatctg tctttcattg acatgtgctc ctggcaaagc
    19141 aatgacttca tcaaatcgcc tagtatgggc aaagtctagc tggaaactag ccgctttttc
    19201 tagtttgatt gtttctccgg tttcatttct tatctttaca gatcgtgtga tcactgctct
    19261 atcagtaaat atggtataga acaaatcgaa ataaatcgct gtttctctat ccttaagtga
    19321 aatcaccaac gtttgtgcct ctgacttgtc catcacataa gtttgaggca agccttcgat
    19381 ctctggcttc ccatctgtaa tataatggct gtcatatctc agatccagta agtctgatcc
    19441 attcttgcgc tgaatgatcg atgcgggcgt tcgaaagtcc atgctgccat gagaagagta
    19501 ttcttgcggt agtgtatctt tcgacagaga ccggtcagga tttaagggaa catttcctga
    19561 aaatccacga tctcttcggg gataattttt attgtctttg tactgcttga ctggtttgcc
    19621 aaaataaata tgcgccaata cattgctttc ttctatcttt atcagataag aaagaaatgt
    19681 atttcgtaaa tggaagactc ggctcttttc atcaaataag atgaaatttt tatctgtttt
    19741 tctatgcgta atatccatca tttcactccc aacaaaacgg aaaccgttta ctttttttta
    19801 taattcctgt atactgttta ctaaacaatt ttgtcaataa aaatttttta tttttttgag
    19861 gagtgtgtaa aaatggttgg aattagagat gtcgcacgaa aggcaaatgt ctctcctgct
    19921 acagtttccc gtgtgttgaa taacgatcag acgatccatg tggctcagac tactcggcaa
    19981 cggatagtag aggcagctgc tgcgttggat tatgacatca gtactcgtaa atatatcaaa
    20041 aagagaatgc cttcgattgg tgtgatctct acgatcggca aagcgagcga agaacaggat
    20101 atctattaca aacatttgcg agtagggatg gaagaagaag ctcgacgtct gcatttaggg
    20161 atgaatcgaa tctataatct atctgataat cctaaacaat gggaagatct agatcagtta
    20221 ggtgcggtga tcgttgttgg gactgttacg aaagaatcga ttaccgcctt gttaaaacaa
    20281 aacatgcaaa tagtcgtcgt ggataaccct gacatccagc aagaggtcga tatggtgtat
    20341 gcagatcttg aacggatgac taaaaccgta ctggaattgt tcttagaaaa tggtcataaa
    20401 agaatagcct atatcggggg atataaagtc gatatggatg aattcggtgg gaagcagatt
    20461 tctataaatg aaaagaggat gcgtgcctat cagcatttta tgatcgatca tcacttagaa
    20521 aaatatatgt cttatcatct aggtggctgg acagaaaaac aaggtgaggt acttgcgact
    20581 aatctattag aaaatgaatc ccctcttcct actgccattc ttgtcgggag cgatccaatg
    20641 gcaattggtg tctatcgggc attgaaacaa aaaaatatcc aaattggaga agagattgtt
    20701 gtagcaagct ttgataatat cgagacaatc gcaaacctct cccctggctt gaccagtgtt
    20761 caaatcaatg cgaaatcaat tgggcaagca gctgttcgaa tggcattgga gcgaattgac
    20821 ggtatacggg acgaaccaat cattttgact tatcctgcac gattgattgt tagggaaagt
    20881 tttatcccaa gaacaaaaag gtattgaaag agaggttgtg aaaagccgct tcgtttcttc
    20941 atactcaaaa cgaaacggct ttttcacaac ctcttactta tacttattca caaaatccaa
    21001 tgtctgctgg taacaatttt gcgattcttt tagcgtgtaa tcaaattggt attcatgggt
    21061 aatctctttt tttgtatctg tataaaacaa ggattgcacg ggtaccttta attctgtcaa
    21121 ccgattttct aatgcttgac cttgctcctg gaatgagtat gcatttccgt cagttatata
    21181 cgttggcgga aattccttag aaacatggtc agccacacta gcttctttca attgctcact
    21241 cgttttccaa tcttttgttc caatcaacga ccacgcaacg gttttgacga aaaacttcat
    21301 aaatcgatca tccgaatgct gctgtgctgt tagcttcaaa tcaacaggtc cgcaataaga
    21361 aatggttcct ttcagactat cttttggaag tagctgtttg attttcattt gtttagcata
    21421 cgcatcattc gtttgtatag ctgcatattg caatgcgatt tgtgaacctg cactatctcc
    21481 accaaaaaat aattgttcca tgtctagcaa tttgtcgtct ttttcttcag ctaataaatc
    21541 tttgatcagt tcattcactt gaagaacttg attagggtat tctgaatcag gcgctaattc
    21601 ataattcatc gcaaccactg cgatgttggc gtctgaaact aattttgtcg caaattcttt
    21661 gacacccgat ttatctccgc cgacgaatcc tccaccatgt acccaaaata gaacaggaac
    21721 aggccccttg ctgttttttg gatagtagat gtcataagta ttctctttat acttggactc
    21781 atacgtcaaa tctgtttttt tcgccacgtt tttttctgct tgatcgaacg tttttttatc
    21841 agtgatttga acagtatttg aaaacatatg gttgatcaag aatgctccag gtctggggga
    21901 aagctggaag gcaagaaaga ttgcaaacgc gatcccaaga atgattccga agaaccatcc
    21961 gataaattta agaattttct ttttcataag gctccctcag tagttagtat taagcattct
    22021 gattatacca tagtgttatt tcctatcaag ctctcctaga tgatttaatg attttcccca
    22081 aacttcttct gcaatgcttt tgacaaaaga aattttttcc attgttcttc aaacaaaaca
    22141 ttttcttctt ctgttgaagc aaatccacat tgaggactta agcacaaacg atccaaaggc
    22201 agatatcgtg tcgcttcgta gatccggtca atcacttgct ggtgctcttc catttcgcca
    22261 tttttcgtta cagtcaaaat ctaagacaac taatttatct tcagagactt tctctaaaag
    22321 aacaaaactc ccagcacgtt cactatcgta ttctaaataa taggcacgga cattttcttg
    22381 agtaaaataa tgggtctgct acgtcgtcat cccccctgat gccgccaaaa tcgaataata
    22441 atttccgcgt caaacatgta tatttagtgt tgaatcattt gagaatatga aaataaaaat
    22501 ctttttgatc aatcagttaa tcaaattgaa ataacgaaaa atctgagaca gaatgacgtt
    22561 cattctgacc cagatttgat tttgcacaac tcaacagtcc ttattggcaa atcgccaaaa
    22621 taatgtagac taactaaaa
//
LOCUS       DAFLWQ010000044        21862 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.045, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000044 DAFLWQ010000000
VERSION     DAFLWQ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.045"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            209..2884
                     /locus_tag="L1V16_001681"
     CDS             209..2884
                     /locus_tag="L1V16_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HBN1276024.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGIAKIEATFVEAQKKIWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            3066..3305
                     /locus_tag="L1V16_001682"
     CDS             3066..3305
                     /locus_tag="L1V16_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276025.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLAFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNGRVAKEWYLVHS"
     gene            3321..4694
                     /locus_tag="L1V16_001683"
     CDS             3321..4694
                     /locus_tag="L1V16_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1276026.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGGKADRPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLAYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEAHEAKVVRHIFQLYLTKKYGYKKLCQRLTQQKFFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKTIFLQAQEIRQSRCTAKKDTYPYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKHKVIQQKKQEAQWLKAFEEGNCSLEELKQQLQALQ
                     KPRSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDHVCRIEVTKEKTVCGIYFRQMTQ
                     NILEGNE"
     gene            4698..6335
                     /locus_tag="L1V16_001684"
     CDS             4698..6335
                     /locus_tag="L1V16_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1276027.1"
                     /translation="METTPTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMSYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPKPILVKGTHEPIISEEDY
                     QKVQERLVLEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQQGEPIQVKDVQRILTSLDRFLAQSEKKQVKALYRTFIEKITFDPNYKEILEITM
                     KFTPAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            6498..7430
                     /locus_tag="L1V16_001685"
     CDS             6498..7430
                     /locus_tag="L1V16_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276028.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYYTLCSKCNSFFGSEYVEEYIRFAEDNKNFLYNNTSLK
                     NGKSDLTHSIKKMNSLRVAKAIVAMFFSLNGDEDSMDKPFLDSVREYLSNPKSTLFPH
                     EDYKIIMNYYLPIGAPQNSKIKIPNDIVNDGDTHNVIKGFMPLDLSTGRKIRFSEIQY
                     EGIGFTLIDLKNSTFEIKEGLDLKNLLCADDKIKKIQLYKVPILTPTVLTMLEMENNI
                     NYIDSGSDLLIRWQVITNFLMELKKYSNTQTKFS"
     gene            7555..7812
                     /locus_tag="L1V16_001686"
     CDS             7555..7812
                     /locus_tag="L1V16_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBN1276029.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKALYHTFIEKITFDPNQK"
     gene            8044..8448
                     /locus_tag="L1V16_001687"
     CDS             8044..8448
                     /locus_tag="L1V16_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
                     /protein_id="HBN1276030.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFLASHIYGKILSAKFE"
     gene            8467..11124
                     /locus_tag="L1V16_001688"
     CDS             8467..11124
                     /locus_tag="L1V16_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1276031.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKK
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLEDVEFFSIED
                     MILGMNISKFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLLERVSDA
                     IYILQNDLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQTHFK
                     QSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
     gene            11196..11672
                     /locus_tag="L1V16_001689"
     CDS             11196..11672
                     /locus_tag="L1V16_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1276032.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            11686..12474
                     /locus_tag="L1V16_001690"
     CDS             11686..12474
                     /locus_tag="L1V16_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1276033.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            12467..13273
                     /locus_tag="L1V16_001691"
     CDS             12467..13273
                     /locus_tag="L1V16_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1276034.1"
                     /translation="MNKMSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALS
                     PILRKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKV
                     GTMGPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEF
                     GYKQGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQP
                     MLDKILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            13292..13687
                     /locus_tag="L1V16_001692"
     CDS             13292..13687
                     /locus_tag="L1V16_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBN1276035.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            13689..14810
                     /locus_tag="L1V16_001693"
     CDS             13689..14810
                     /locus_tag="L1V16_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBN1276036.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            14830..15699
                     /locus_tag="L1V16_001694"
     CDS             14830..15699
                     /locus_tag="L1V16_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1276037.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            15900..16409
                     /locus_tag="L1V16_001695"
     CDS             15900..16409
                     /locus_tag="L1V16_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HBN1276038.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            16509..17159
                     /locus_tag="L1V16_001696"
     CDS             16509..17159
                     /locus_tag="L1V16_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276039.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            17610..18548
                     /locus_tag="L1V16_001697"
     CDS             17610..18548
                     /locus_tag="L1V16_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBN1276040.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            18561..19613
                     /locus_tag="L1V16_001698"
     CDS             18561..19613
                     /locus_tag="L1V16_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1276041.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            19879..20514
                     /locus_tag="L1V16_001699"
     CDS             19879..20514
                     /locus_tag="L1V16_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBN1276042.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            20705..21496
                     /gene="msrA"
                     /locus_tag="L1V16_001700"
     CDS             20705..21496
                     /gene="msrA"
                     /locus_tag="L1V16_001700"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBN1276043.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
BASE COUNT         7436 a         3244 c         4449 g         6733 t
ORIGIN      
        1 taattgaaca atattttcct aaataattta ataaggattg atttattgta aaagaaaaaa
       61 gttgtgattt tggaaatcac aacttttttc ttttgtcaag attttgagtg ggatatattt
      121 ttgtagaact gaagatcatg aaattatgag aggttggagg taatgtagtc atacaaataa
      181 aaatttttta gaaagtgagt ggtaattaat gaaaatgaat cacacttcaa ttcagaagca
      241 tttacaactg ttaaatacac tggggatttc ttatgttaat ttgagaactt tttctacatt
      301 aaacaagaaa accgtttctc atattttttc tactgcagat tctcaagcaa ttattaacta
      361 tttagaaaaa cagaaattgt ctgaaggtac agtaaacata acttataatc ctattaaaca
      421 agaggtgatt acacaaaaaa agcattctgt gagagacaat gatattgaaa aaattcggtt
      481 tgtatttatt gatattgacc ctaaaaggaa agagggaagt gcaacagata gcgaaaagaa
      541 aaaggcagaa aatgttatgg aacaagtaga acgttatttg aaagaaaaga gaatagaatc
      601 atttgtaaaa gttgatagtg ggaatggcta ccatattttt cttcccataa atgaacaacc
      661 aaataatcac gagacgattc ttactattca gaattttctt caattacttc accgaagatt
      721 tggagtagaa gatgaagttg atattgatac ttctgtttat aatccttcaa gattatgcaa
      781 attagttggt acaccagcgg tcaaaggaaa gtccacaaaa gagcgtccgc atcgtttatc
      841 tagtttcctt tctattcccg ataacataga tagaagtaat tgttttaaaa ttcttgaaca
      901 gatagttgaa gaaaattcca tgatgtcaac ctctagagta aaaagccatc catcttttag
      961 agaagtgtta ccttttattc aagcagacta taaacaatgg ttagctcact atcctgaatt
     1021 aacttatacc ataaaagagg gcgatcataa aggagttacc ttacttatat ttgacgaatg
     1081 tccattaaga aaacacacga ataattctaa tggttcttgt ttgtctgtta cggctgataa
     1141 taagattcga tttcattgtc tgcatgcttc ggataaaaat aaagatattc aagactttgt
     1201 aaaaaaatat ccgttgccaa aacctgtaaa tccttctgta gaatcattag aatccaatca
     1261 agaatattat tttgaccagt ttaaactgaa tcaagaagga gtatttttgg tgaaagaagg
     1321 tcaagaagaa aaagttgctt gtccgatgtt tattaagcaa atacgcaaaa atatcgaaca
     1381 aaaagtcatt acacttgttc ttgcctatta tgtcgatcat tgttgggatg aaatagaaat
     1441 agaaggtgga tgtttacaaa ctaataattt taaacaatta gcaaaacatg gcttaatcat
     1501 taaagctaga agagaagctg aagtcgttga ctttttacag attcaacggg agaatgctcc
     1561 aatctttttt gaacatgaat ctcttggctg gaaaaaagaa aatgaagcaa tgatttttca
     1621 gttacaagat tcttttggac gtgaaattcc ttctgtatta actaaaaact catgctacca
     1681 attaacaact aatggtacag aagcggaatt tgacgcattg gttcataagt atgttttagg
     1741 aacgaactta gaacttgctt ggtcgattgg tattgcttct attgtgttag gctatttaaa
     1801 cgttacgaag gctaatactt ttttgagttt actaattaac ctacagggca agagcacaac
     1861 gggtaaaacc actacgttac actttattgc ctctttattt ggaaatccaa ctacggttct
     1921 tagaaatatg aatgctacca ataaagccat tataaagcta gcatcaaaca atcagggagg
     1981 tgttccacta atactagatg agttaggagc agcaactcaa aataacttta gctcgttgat
     2041 ctatcaatta gcttcaggag aagaaaggct aagattagat tctaattgtc agcttatgcc
     2101 acaagagact ttttctgttt tgacccttac ctcttctgaa gagcgtttgg aaaattattt
     2161 caatgagaaa ttaactggtt tgaaagttcg atatatcgaa ttttctgata tcaagtttac
     2221 aaaggatgcg aatcacgcag agaaagttaa aagtctttct tctaatactt ttggttgggg
     2281 tataaagtta tttcttttga aactctttga acaagggatt gcaaaaattg aagcaacttt
     2341 tgtcgaagct caaaaaaaaa tatgggctgt tttacctgaa cattctttga agcaacgcat
     2401 tggtaataat ctagctttga tttatagtgg agctctccta attcaagata tactgggcta
     2461 tcctttacga ttagagcata tacagacggt gcttattaat tcgtacgaac agttaattgt
     2521 agatactagt ttaggaagtg agcaaacggt atttgaccga gtgaaaacgt tgttggtgat
     2581 gaatagccat aaatttttaa caaacagtga caacaaacat acgcccagta cgatttgggg
     2641 aaaagtatca attcaaaaaa atggggatat taaggtaaat atttttccta tcccgtttga
     2701 ggacttgtta aggcgagaat ttcaagtaaa ggatctaacc tatcttttta gacaattgct
     2761 tgattcgggt aatatgtgtg cagaaaaagg gagaagaacg aaacgtattc acatgaatcg
     2821 tcaagttctt ccaacatacg agattctatt accttcttca ctcaaatcgt attttcgatt
     2881 gtaatttaga ataaaccaaa gtatgaaagt gaggcaccat gttatggaaa tatttcttat
     2941 tgatttagca aaacaactga ttacttatct gtatgatgac gagcaaaccc aaacggaagt
     3001 aaatgaagct tgatctatgc ttcatttact tcattcaatc aaacatttaa gaaaggggaa
     3061 ttctaatgac taaaaataaa atgacactaa aagcagaggt tcttctgtat attcaagaac
     3121 atttttctaa tcaagccttt tttacaaaac caatttactt ggctttcgaa ataagagggg
     3181 tatctgctgg atctattgga ggtactcttc aagcgttgaa gaacgaagga tatttagaaa
     3241 atcactttgt gcaacgttcg ttcaatggaa gagtcgcgaa agaatggtat ttagttcatt
     3301 catagagagg tgattcaagc atgcgtgtgg cttgttatga tcgaacgtct gtttatgaag
     3361 aagcgaaaat cagtaatgac gctcaatatg atgcagtgaa agagtatgtt ttagagaaat
     3421 atgaacaaat tcctcaacga ttttcagaca aaggagaatc aggtggaaaa gcggatcgtc
     3481 cagcttttcg acagcttaga gcttgggttt gtgcgtcaga agaagagggg gtgatctatg
     3541 tctggcgtta tgatcgattg gcacgtcaag ccaaaatagc cttagaattt attgagttgt
     3601 gccaacaaca tcaggttcaa gtttattcga tttctgaacc tcttcctgct tctttctcgc
     3661 acgcgtcaac gaataaacta tttgtgcaat tattgttcac ttttgcagaa caacaacgaa
     3721 acgtcattat tgaaaatgtt cgtgccggac ttgcctataa aaagcaacaa cggcaatatt
     3781 tgtcttctgc ggttccatat gggtatcgtt tagtgaatgg gaaaatccaa caagaagcac
     3841 atgaagcaaa agttgtccgc catatctttc aactttattt gactaaaaaa tatggctaca
     3901 aaaagctttg tcaacgattg acgcaacaaa agttcttctt ccgtgaacgt ccttttcagc
     3961 cctatcatat ttatagtatc ctaaaaaatc cattgtacta tggcgaaatc aaaggaggat
     4021 ctttggggaa gtatctagga acctttgaac cgattctctc gaaaacaatc tttttacaag
     4081 cccaagagat tcgccaatca aggtgtacag ctaaaaaaga tacgtatccg tacttattac
     4141 gtcaaaaaat tcggtgtccc ttctgtggtc gtcatctgag ttcgaagtat caatggaata
     4201 caaagaagac gaagacgctt cattattatc attgtaccga ccgaagctgc caaggaatct
     4261 ttcttcgggc agaaagggtt gagtcagaag tattggaaaa gatacaggct ttttttcaat
     4321 acgaaggcgt ctatcaagcc ttgattgccc aattgacgca acaattagcc gaaaagcgaa
     4381 aagatgaaaa acacaaagta atccaacaaa agaaacaaga agcacaatgg ctcaaggcat
     4441 ttgaagaggg caattgttca ctggaagaac tcaagcaaca gctgcaagct cttcaaaagc
     4501 cgaggtctac ttcttcgttt ctttcactcc aacagtgtga agcaaaagtg aaagaatggc
     4561 ttcaactaaa agacctctct agtcgacaat tgttatgtga ccatgtttgt cggatcgagg
     4621 taacaaagga aaaaacagtc tgtgggattt acttccgaca aatgacacaa aatattttag
     4681 aagggaacga atgatctatg gaaacgacac caaccaaacg agtcgcattg tatattcggg
     4741 tgagtaccca agaacaagct ttagaaggac atagtattca agcacaagaa caaaatggac
     4801 gacagtttgc cgaacggatg agctatgaag tggtagaagt ttatgccgat gaagggatta
     4861 gtgggaaatc cacaaaaaat cggttcgcct atcaacgaat gatgaacgat gctcggaacc
     4921 atcgttttga tctactagtg atttggaaat tgacccgtct cggacgcaat atgttagatg
     4981 tcttacaaac cgtcgaggaa ctgttgcgat atgatgtggg gttacattcg atctcggaac
     5041 aatttgacgt gactacttcg acaggaaaac taatgttaca actccttggg agtttcggtg
     5101 aatttgaacg caaccaaatt gcggagaatg ttcagatgtc aatgcaaagc ttagtgaaag
     5161 ataaaaagcg ttatgcaggt ggacgacgtt taggctatgt cagtggtatt gacacgaatg
     5221 gtcaaaaaca attggtcatt gaaccagaag aggcgaaaat tgttcgtctg atctatgcaa
     5281 aatatttagg cggagcaggg tatcgagcga ttgccaattt tttgaatcgt caaggatatc
     5341 aaacagtcaa aaagaatgct ttttctacca cggcagtcaa agatatctta cgcaataaaa
     5401 tttatgcagg gtatttagaa tatgcacgct atatcaattg ggaaaccaaa cgacgaaagg
     5461 gcaagaaccc aaaaccgatt ttagtgaaag gtacccatga accgattatt tcggaagaag
     5521 attatcaaaa agtgcaagaa cgccttgttt tagaaggcaa acagcccaaa tggaaccata
     5581 caggtgaaaa tgtattgaca ggcttgttac gttgtccaga atgtggggca ccgatggcag
     5641 cgagtaatgt cacaaatact ctaaaggatg gcacaaagaa acgaattcgg tattattctt
     5701 gttcagtctt tcggaataaa ggagcaagtg tgtgtcatgc caattcgatt cgtgccgaac
     5761 aagcggaaac atttgtcgcc gaccgattaa aggagatcgt tcagctacca gaagttcttc
     5821 cccgattggt ggcagcgtta aatgaagaaa tagtgcgaca aagccaacca ttggaacaag
     5881 aactcgtggt gttactggaa cgaaaggaag aattgaagac taaaattgaa aaatgggaag
     5941 ctgctttgga agatagtcct gaattgtttc cgatgttaaa agaccgctta gacgaattga
     6001 ctgaaaaacg acgacagttg cacattcgag aaaatgaaat cttagggatc tttcaacaac
     6061 aaggagagcc gattcaagtc aaagatgtcc aacggatatt gactagtttg gatcgttttc
     6121 ttgcccagag tgagaagaag caagtcaaag ccttgtatcg tacctttatt gagaaaataa
     6181 cctttgatcc taactataag gagatattgg agattacaat gaaattcacg cctgccgtgg
     6241 tacaacaatt gaatgagcaa tatcaaatag ccgtatccaa aacaaaggat acggctattt
     6301 ttgtgttaaa gacacccttt acgttaacga tctagtctag gttatatcaa acaacgttag
     6361 aggggcgcta acgcttctct agcgatttga aatcgttaga tgagtcgtta gggaggtcct
     6421 tatcataaat agggatattt attaatgaat atttgaaata taattgtata taagaattaa
     6481 aaagagtggg gatagatatg aaaaagatgg gtaagtgtat tttatgtgaa aaatacactg
     6541 aacttactaa agaacatgta ccacctaaaa aatcagggaa tactggaggt aaaaagacca
     6601 gaactggtaa tttagatgat ttccttaaga gcgattttac aaaaggtgat tttccgaagg
     6661 ggattaaaag gaaacctcaa ggaaatgttt attatacgtt atgtagtaaa tgtaatagtt
     6721 tttttggtag tgagtatgtt gaggaatata ttagatttgc agaagacaat aaaaatttcc
     6781 tttataacaa tacaagttta aagaatggta agtctgattt aacacattca ataaagaaaa
     6841 tgaattcact tagagttgca aaagcaattg tagcaatgtt ttttagttta aatggggatg
     6901 aagattcaat ggataagcca ttcttagatt cggtacgaga atatcttagc aatcctaaaa
     6961 gtactttatt tcctcatgaa gactacaaaa ttataatgaa ttattatctt ccaataggtg
     7021 ctccacagaa ttctaaaatc aaaattccta atgacattgt aaatgatggt gacactcaca
     7081 atgtaataaa aggttttatg ccccttgatc tatcaactgg gagaaaaatt cgattttcag
     7141 aaattcagta tgaaggaatt ggttttactc ttatagattt aaaaaattca acttttgaaa
     7201 taaaagaagg attagattta aaaaatctcc tttgtgcaga tgataaaatc aaaaaaatac
     7261 aattgtacaa agtccctata ttaacaccaa cagtacttac aatgttggag atggaaaata
     7321 atattaatta tattgactca ggttcagatt tgctgattag gtggcaggta ataactaatt
     7381 ttcttatgga attaaaaaaa tacagtaata ctcaaacgaa gttctcttga agttataaag
     7441 aatacaataa atataaattt cctttagact atattaaaat cagcaatcga aggaaaataa
     7501 acgaagaaaa tggtacgcaa aatctaacta ttagagcaaa aacaggaagc tgctttggaa
     7561 gatagtcccg aattgtttcc gatgttaaaa gatcgtttaa atgaattgac tgaaaaacga
     7621 agacagttac aaattcgaga gaatgaaatc ttagggatct ttcaacaaca aggggaaccg
     7681 attcaagtca aagatgtcca acagatattg actagtttgg attgctttct tatccagagt
     7741 gagaagaagc aagttaaagc tttgtatcac acctttattg agaaaatcac ctttgatcct
     7801 aatcagaagt agatattgcc gatcccgatg agattcacac ctactgtgat ttgataattg
     7861 aatgagtaat atcaaatagc cgtatccaaa ccaaaggata tggctatttt tgtgttaggg
     7921 atatacgtca cgtagcttgt tatcaagaat aagtttcttt atttttttgc tttttctaaa
     7981 actgagtatg ctaaaataag agggtatata gcaactttaa ataagagata ggagtgtatc
     8041 tttttgggtg cagaattaaa tcagaagtta tttagtgcgg cagataatct ccgtagtaaa
     8101 atggatgcgt cagaatataa aaattattta ttggggctga ttttctataa atatttatcc
     8161 gaccgtttgt tggaacaagt ggttctttta gcagatgaat ccttagagga atatgacaca
     8221 gtaagcaaac aaacgatgtt gtatcgtgaa ttactttcag atgaagaatc aaaagaagat
     8281 ctgattgcaa caatcgttga tattttgggg tatgcgattt cgccagagta tcttttcaac
     8341 gtcttagcgg atcaagcaaa acaagcaacg ttccaattga atgatctaaa caaagccttt
     8401 ttagcaagtc atatttatgg aaaaatactg tcggcaaaat tcgaatagtg tcgaggaggt
     8461 gctgtgatgg aagaattaaa agaacgcatt gtcaattatg tcatagagaa ctctgagatt
     8521 aaaaataaat gggggaacaa tacagcacag aaaatatctg aaaaattaaa tgttagtcgt
     8581 aatattgtct ctcaatattt gaatgaattc gtaaaagatg gagaatttgg aaaaatcaat
     8641 actcgtccag taatcttctt ttctttaccg gagaaagttc caaatcaaca aatttttagc
     8701 tcttcagagg aagcggaaaa atggtatgat agctctttta gggttggaat agaaagggtt
     8761 atcggaagtc aaggaagtct gcgaaatgta attgctcaaa ttaaagcagc aatctactat
     8821 ccgccaaatg gcttacccat tttacttcat ggcgagactg gaactggaaa aagctattta
     8881 gcaaattatg tgtataagga tttgttggcc aataattata tagaagagaa ggcatctttc
     8941 atttcagtta attgtagtga atatgccaat aatccagaac ttttcttgtc caattttttt
     9001 gggcatgtaa aaggtgcata tacaggagcc gaagatggaa gaaagggttt agcagaatta
     9061 gctaataatg gagtcttatt tttagatgaa attcatgcat tgagcaatga atgtcaggag
     9121 aaactttttc agtttatgga tacgaggaaa tttcatcgga tgggtgataa tgaaaactgg
     9181 tacacatcaa gttgctggat tatatttgca acatcagaac cacctgagga taaactatta
     9241 tcaactttgt tgagaagaat acctgtaaag ctaacacttc caacattaga cagtcgttct
     9301 ctttatgaaa gaaaacagtt aatcaagata ttttttaaat cagaagaaga aagactagca
     9361 aagaaaatac tgatatctca acaattatta gattttttat taaactatcg ctttagtgaa
     9421 aatgttggca atttgaaaaa tatcattcaa ttgacctgtg ccaatgcctt ttatttctta
     9481 gatgatttgg aagaacttta tattcagatg tatcatttac cacaatgggt gaatttcaac
     9541 ggcatgaagg ttatgaaaag acagaatgaa ttaaaatata ttcaaatgga tgatttggaa
     9601 aaagtagacg aagtttttaa tatcaacgaa cttatagagt atctttatca aacgtggaag
     9661 aaagacactg ataagcagca gctttttgag aaatatgata gatattttag acaaaagaat
     9721 gttgatatcc aaaataattc agctttaaca tatcccacct atcaagagat tcgatttaga
     9781 cagtatgtta aggaaataga gagagatttt caaatagaat ttgactatta ttatcttcaa
     9841 ataacgtcta tctttttgaa ttcttggatt tatcaaatcc aattaacatc ggacgataaa
     9901 ttatattcct tcatcaatga tattaatagt tggtgtagtc gagaagttca attagtcaat
     9961 cgttttattc aaatagggga tatttattta acaaaaattc aaaaaaatgt tttggttatt
    10021 ttatttaagt taatgtgtag taaagaattt cagcaaaaac gtttagcact gattttggct
    10081 catggagatc taacggcaac ctgtatagca agtactgcta ataggatcgt tgagagatat
    10141 atatacgacg ccattgatat gccactaatg acttcaagta gtgagattgc agacaaaatt
    10201 aatagatact tacaagagtg taccggatat gaagaaatta ttttacttgt tgatatgggt
    10261 tcactggaga aaatttatct aaatttggaa ctagacgctc aaaaaaaatt cggactacta
    10321 aacaatgttt caacaagaat ggctattgat gttgcaaatc agatattatt agatttaccg
    10381 cttaaacaga ttcttgaaca agtaaaagaa aatcaaaatg tggattatat ttatgaatca
    10441 tcaaatatta agaaggatat gattgtctgt tcttgtgcaa gcggattagg aacttcgttt
    10501 aaattaaaaa agatacttga agatagcttt ccaagggata ctgatcttgt catagaaacg
    10561 tgtgactatt actctttagt gaatgaaaac tatttatcgg agcttcgtaa agagaacaat
    10621 attcttttta ttgttggaac actaaatcca catctagaag atgtagaatt cttttcaatt
    10681 gaagatatga ttttaggaat gaatataagt aaattctcca atcaattgaa tagacacttt
    10741 aatgataatg aactgaaagt tttgaacaat aatattctga agaattttag tctaacgaat
    10801 ttaatggagc aattgaccat attaaatccg actaaattat tagaacgggt ttcagatgct
    10861 atatacatct tacaaaatga tctaggaatt tcatttgata ataatacgtg tttcggatta
    10921 tatgttcaca ttagttgctt aattgaacga ttagtaaaac aaaatacttt ggaagatgaa
    10981 atttatttca atgaaacgag tgaggaattt caaaaatttc agacacattt taagcaatct
    11041 ttcagtgtcg ttgaacatta ttatagtgtc gacatcccga ttcatgaggt taaatacgtt
    11101 tatgattatg taaaaagagc ttgatttatc aagttctttt tgttttggca tggtaattgc
    11161 ttgtaagaaa atgaaagata aaggaggaag tatttatgag tattgttatg tcgagagttg
    11221 ataaccgttt attgcatggg attattgtca cgcaatgggc accaatgtct aaagcaaaca
    11281 gagtgatggt gatcgatgat tctgtcgcaa ataacgacat ccaaaaatca agtatgcgtt
    11341 tagctagacc tgctggaatg gctgtatcaa ttatcactga agaaacagcg attgcgaatt
    11401 ttaaaaaggg gaaatacgat caggaaaaag tatttgtcat cgtgaaagag ccggaaacaa
    11461 tccttcattt agtagataac ggtattagaa ttgaccgact aattgttggc ggtactgttg
    11521 ttaaagataa tgcattacag ctatcttcta gagcctatgc atcagatgaa aatatcagca
    11581 cgtataaaaa attgttggat tctggtgtag aaattgttac acaatttgtt ccggcggata
    11641 aggcacagga aattcaatca aaattaggat aaaggagtaa ggataatgca ttttactatt
    11701 tttcaaatta ttatgctgac tatattagca tttattaaac atgttgatta ttatgggatt
    11761 ccgatgatct ttgtaaatta cgcagttttt tggggattat tcacaggaat tttgatgggt
    11821 gatataaaaa caggtttgat agttggcggt acagttcaat tgatgtcatt aggagttgcc
    11881 ggttttggtg gctcatctgt accggactat ggaacgtgcg caattattgc aacggcattt
    11941 ggtagccagc ttggagtaga agccggatta gcaataggac tacctgtagg tatgttaggg
    12001 gtgcaactag atgtaattgt caaaatctta aatggttttg ttgttcgcaa atcacaggaa
    12061 tatgcgaata aacgagaatt taagaaaatg aatagtgttt tgtggttggg gccaattttc
    12121 tttggtttat ctgcagcaat tccagtattt attgccgtta ctttaggaca gtctgctgtt
    12181 aattacgttt tggatgtttt acctaattgg tttatggatg ggctaacatt agccggaaaa
    12241 atgttgcctg ctgttggtat tgcgatgttg ttacgcttta tgcctacagg tcgatacatt
    12301 agttatttac ttgttggatt tttcttagcc gcttttttga aggtacctat tattggagcg
    12361 gcgatcatag gattcgcttt agcatttaat gtgtatcata gagctgaaaa agatgcacaa
    12421 atcactgctt ctgcgggagc ttctgatgtt gggtttattg gggaggatga ataaaatgag
    12481 cgaaaaatat caagtaacga aaaaggatct taggaaagcg aactatcgtt ggttgatgtc
    12541 agtttgtacc tttaattatc aaacacagca aggtgcatct gtgacttacg cattgtcacc
    12601 tattttaaga aaattataca aagatgatga tgaatacatc gaagctttaa ataatcactt
    12661 tcagtattac aatacacagc cttggctggc agccattatt ttaggtgctt gtgttgcaat
    12721 ggaggaaaag caaggattag aagcaaaaga tgcgattaat gactttaaag ttggtacgat
    12781 gggtccaatt gctggtattg gggactctct tttgatgacg atgatcccaa ccatcatggg
    12841 atcaattgcg gcttatatgg ctttagaaaa taatcctgta ggaatctttt tatggttcat
    12901 tttaatcatg gtaatcttct ttttccgaat gagaggcttt gaatttggtt ataagcaggg
    12961 aatgaagatt gttactgaat acggtgaaaa gattaattat ttaactgaag ctgcttcagt
    13021 attggggcta acagtagttg gatcattaat tgcttcagtt atcagtgttt caacgccact
    13081 taaattcact tttggtgaag ttagtatgaa aatccaacca atgttggaca aaattttacc
    13141 aacattaatt ccagtaatta ttactgctgc agcatattat ctactcagta agaaaaaaat
    13201 cagtatgacc attttgattc tactcgttat tgtttttgcg atggttatgg ctgcatttgg
    13261 aatattagcg taaaggaaaa ggatttgaat tatgagaaga ttgatcattg ctagccattc
    13321 aatactagct gagggtttta aagagacact agagttttta acaggtatgc ataatcaaat
    13381 tagtagctta tgtgcatatg tcgaagaaat tgatgatata gatgaacaaa ttaaagagtt
    13441 agtggatact acagacgaaa taattgtttt aactgacatg gctggaggaa gtgtaaatca
    13501 aaagtttttt acctatattt ctgacagagt gcacgtaatt gcaggaatga atcttccctt
    13561 ggcaatgtca atcgctttgc agttaggaaa tgataattta gatattggag caattattgc
    13621 ggaggcacaa caacaaatca tctatatgaa taatcaaaaa agtgaagaaa ggatagagga
    13681 cgaataaaat gaattgttta aataatatat ggctccacaa gggagaggaa agtagaacta
    13741 tttcaccaga aaataaaaat ggtgaaaaag ggaaagcggc aatgacagcg agtcatctag
    13801 gaattgggag aaaagggtca ccttctgttc cgataaatgc tggagagaca attactttag
    13861 cagaaatgga aggccctgga attttacgtc atttttggat gacagtgaca gacaaaacaa
    13921 tcgctgggag tttcgtctta cgtgatttaa ttttgcgtat ttattgggat gatgaatcca
    13981 ctccttctgt agaaagtcca ttaggagatt ttttttgtaa tgggtttggg acaagatgcg
    14041 aagtgaattc cttaccaatc gtagtgaatc caacatcagg gatgaattgc tattttgaga
    14101 tgccatttcg aaaaaaagct aagattactt taacgaatga acatcctgag tttattaagc
    14161 acatttttta tacatttaat tatgcattga ctgaagtacc ggatgatgcg atgtattttc
    14221 atgctaaatg gaaccgtgaa cccatcacga caaaaggaaa agattacacc cttattgatg
    14281 gaatcaaagg cactgggtat tatgtaggaa cctactttgc tttgtgcgca ttggaaagat
    14341 actggtgggg ggaaggagaa tttaagtttt atatagatgg agatgaagat ttccctacaa
    14401 taacatctac aggagcagaa gattattttg gcggcgcttg ggctttccat aaaaagaact
    14461 ttggagaaag ggcatatgct caaaatttta atacgctatt tatgggctat ccttttcaat
    14521 ctaaaagaga tcacacccgg gattatttta gtgctggaaa acctaatcca aatccagttc
    14581 atggttttgg cgatgatgct ttaccgatgc atgggttgta ccgctggcat ttacccgacc
    14641 ccattagttt caaagaaaat ttacgtgtta ctttccaaac cctaggaaat gatgacatca
    14701 agctttatga gcgtcaagac gatatttctt ctgttgccta ttggtaccaa aaggaaccac
    14761 atgagttttt cgaaaaacta ttagacaggg aagaacgaat tcctagataa aaggacggtg
    14821 gagtaagaaa tgtatggctc aatagaagca ggtgggacta aatttgtttg tgccattggc
    14881 aatgatgatt taaaggtttt agaaagagtg agttttccta caactacacc gaatgaaaca
    14941 atgagtttgg taattgattt ctttaatcac tataaagaac aattagaaag cattggagta
    15001 gggtcatttg gaccgattga tatccatcgt gaatcaaaga cctatggaca tatcacctct
    15061 actccaaaaa ctgcctggaa aaattttgat tttgttggaa cgttgaataa gcatttcgaa
    15121 attccaattg cctggacaac cgatgtgaat gctgcttgtt acggggagta tgtttcaggt
    15181 catggaaaag gtttatccag tgttgtttat tacactgttg gaactggaat tggtggagga
    15241 gctatacaag atgggatttt tgttgaaggg tttagccatc cagaaatggg gcatacgtta
    15301 gttaagagac attcaggaga tactttctct ggtacttgtc cttttcatca tgattgtctc
    15361 gaagggttgg catctggacc cgctatcgag atgcgtacgg gaaccaaggg acaagatctt
    15421 tctatagaag atccgttctg ggaaatcgag gcggattata ttgcacaatg tgcctgtaat
    15481 acgaccctga tgctttcacc agatattata atttttggtg gtggtgtcat gcaacaagaa
    15541 catctgaaaa agaaagtaca aagacgtttt ttagaactaa ttaacggcta tgtcgatacg
    15601 ccaaatatcg aagaatacat tgtcacacct aagttagcag ataatgcagg aactatagga
    15661 tgcttaactt tagcaaaaga tgttagaatc aattcttaag caaaaaagta ttagtcaata
    15721 aaatgcttat gaagtccgat caacttaatg tggtcggact atttgtattc agcaatatca
    15781 ttcactcatg atacccagcg ccttatcata agtgatgcgg tttttatcat tgatcctaaa
    15841 aatcttagca agacaaaaag tacgtaagaa agtaaagact aaatacttcg gaggaacaaa
    15901 tgaataacaa tgataggtta ttgcgattgc gttatgcgat tgatttgaaa gatacggatt
    15961 tgattaaagc ttttgagcta ggcggtgtac cactgactaa agaagaagct caggcggtac
    16021 tgaccaaagt acaggataag aacaaagata atgcagaaaa taatgtgtat gaaaaaacca
    16081 tcaacaacca agtttttgac gcattcctaa atggcctgat tctcttggcg cgtggtccgc
    16141 aaaaagataa gccgatagta gacacgccgc aaaaaagcaa ggaaatcaaa tatatcaaca
    16201 atgtgttgct aaaaaaatta aaaatcgcct tgtctatgac cactgatgat attttagacg
    16261 tttttgctga ggcagaaatc tatccatcaa aaggcgaaat cggggcattt ttgagaaaag
    16321 aaggccaacg aaattttaag ccttgcggag ataaatatat gcgtaatttt ctcaaggggt
    16381 taggaattta taatcggaga aaagtataaa gaaatttcat gagaaatcaa aacaatggtt
    16441 gttttgatga gagctagttt ttgtatgaga ttaaaatatt atcttaatcg aggagctgga
    16501 ttggttttat gaatgatgaa tataagaatg atgaagataa gatgcttttt gaagagatag
    16561 agaatcgatg taggctcaat tttgagcttc ggggaaagat gtctttaata caacaaaaaa
    16621 agtatttagc gaataaatca gagtttactc tgggacatgt tgaaaaatta atctcggatt
    16681 ggattagtag tagaagcgaa tttacaaaaa taaaacagcc gattaaattt gacatgaaaa
    16741 aacttttgtt aaataagagt gagataggta atagagatca atatattaga gctaaagggc
    16801 aagaaataat tgattcatta ggtgaaatga ggtcatacaa ttatttgtat gtaacacata
    16861 gagctgatgg aatggtcatt actgtgggga aatcttcttc taatgatatt tttttagatg
    16921 gagatctttt ttatcaactc aatacaaatc acttgtctgg cactgaaaat ataattttaa
    16981 ggacggaata tggcaatgaa atatttgcaa aatatgatga gattttaaaa aattatttgg
    17041 actgggcttg gataattccg gttgagtcag gagatgctaa gaaactggag agattattgg
    17101 gcgatgaact aattaataaa aaagtaccaa ttttaaatta ttattcccat agacaataaa
    17161 aggctatttt tcatgataat actagttata actgtaaaaa tggaagaaaa tctgggaaag
    17221 aagtttttaa ataagtgtat tgttcgattt taataaataa taagcaatac catccgtctg
    17281 tgttgcgcaa catcgtacta caatgaatat tttttcacaa aaagaaaatc atccatcgaa
    17341 tgaatggaag gttttagtat acacgaggtt aatgccccct cttttataat cagaggagtg
    17401 aggttttttc tatgaatgtt tctattttct tattgctagt ctagtttctc ttacgatgaa
    17461 attgggattc tattccagtt tttattgatt tgctgataaa ataacttgaa tggtggatat
    17521 aaacatgata aataagagaa gaataacaaa acaaggttgt gaaatgattc tcaaatgaat
    17581 ataatagaaa gaaaaaggag gaagaatcaa tgaaaatagc aattgcaggc gctggcgcaa
    17641 tgggaagtcg ctttgggtta atgcttcacc aaagtgggaa cgaagtatta ttaatcgatg
    17701 gctgggcaga acatgtccaa caaatcaaag agcatggatt acaagcaaat tttaatggta
    17761 aagaggtaga agcaaaacta ccaatcgttc ttcaatccga agtagaaaaa gaagatcaag
    17821 ttgatctgat tattctattt accaaagcga tgcagctgga aaaaatgctg caggatatcc
    17881 aatcattaat caaaaaagat acagaggtct tatgtctatt aaatggtatc gggcatgaag
    17941 atattattga gaaatttgta ccaatggaaa atatctatat tggaaatacc atgtggacgg
    18001 caggtcttga aggtcctggt caggtcaaat tatttggaag tggttcagta gaattacaaa
    18061 atttaggtga tggaaaagaa gcagctgcaa aaaaattagc agacaaattg tctgaatcag
    18121 gattaaatgc tcatttttct gacaatattc actattctat ttatcgcaaa gcatgtgtga
    18181 acggaacaat gaacggacta tgcacaatct tagacgttaa tatggctgag ctaggaaaaa
    18241 catcgactgc tcataaaatg gtggcgacga ttgtcaatga gtttgccaaa gtagcagcag
    18301 tagagaagat tgaactagat gtcccagaag tcattgcaca ttgtgaatct tgttttgacc
    18361 cggaaacaat tgggttacat tatccttcaa tgtatcaaga cttgattaag aaccatcgat
    18421 taacagaaat cgattatatc aatggcgcaa tttctagaaa agggaagaaa tatggtgttg
    18481 cgacgcctta ttgtgatttc ttgactgagc ttgtccatgc aaaagaagat agtttgaacg
    18541 taaaataaag gagagattga atggaaactt cacaaaaaat atcaccgaaa atttttctga
    18601 ataaagtcct cgctggtaca gcaacaggaa tcattattgg attgattcct aatgcagtat
    18661 taggtgccat tttaaaatat tttagtgcgt atccctttgc ggtaacgatc gcacagttag
    18721 cagttatttt tcaactagca acacctttga tcattggtgg tttgattgcc ttacaatttg
    18781 gatttgatcc gatgagaatg atggttgtag ccggagcttc ttttgttggt tctggtgtag
    18841 tcaaattcac acctgatttg ggtgaaacgg gtgtttacgt tggtgctggt acaggcgata
    18901 ttattaatac gatgctgaca gcatcgattg ctgtcgggct gattttactg attggaaata
    18961 gttttgggtc agtgtcgatt gtgttaacac cgattgttgt aggtgtaggt gcaggtttac
    19021 ttggttttta tttattccct tttgtaacag caattacttc tgcaattgga tcattgatta
    19081 ataacttcac taccttacaa ccgctgttaa tgtctatctt gattggttgt tcctttgcct
    19141 ttttgattat ctctcctatt tcaacagtag caatcggaat ggcaatccaa ctagatggtg
    19201 tttctgctgg tgcggctgcg atgggcgtag ctgcaaccac ttttgtttta gtagtgaact
    19261 cttggaaggt taataagtca ggtgtgacaa ttgcgattgc tttaggcgct atgaagatga
    19321 tgatgcctaa tctatttaga aaacctgtga ttcttattcc ttgtttagtt agtgcagtga
    19381 ttacagctat tcctgtcgct ctattttcta tttcaggtac gcctgcttct gctggtttcg
    19441 gcgtggtcgg acttgttggt ccgttggctt ctttagatgc agggctaaat ggctttcttg
    19501 ttgttctttg ttggttagtc atccctgttt ttgcggcact aattactcaa tttttatgcg
    19561 agaaagtatt taaactgtat gatcgagaag aagtcttcaa atttttaggc tagtagattt
    19621 tactaagaaa ttttcaatca atggatgcgt aagtgagatg tcaacaacat ctgacttacg
    19681 tttttttgcc tttttgagta ggagattgat gctgacaact gaactcttca gtgccattcg
    19741 attttttaaa atgtagaaga aactcacctt tatgttattg attgttcaaa aggcaactag
    19801 aataaaaata tgtgttaaaa tgagaaaaaa tttgattgtt ggatgtatcg aataatcact
    19861 aaaaagtagg agaagaaaat gatttttttg caaaaatatg gtttttattt tttattatta
    19921 ggtgtgatta gtgatttatc gacaccgtat atccttggcc ttttttatcc caaactgaat
    19981 caaatgacta ccgtaattag tgtgtttggt gacgtagata gtccagtcag acgtgctttc
    20041 ttggtctggt cagttgtatc tggacttttt tttgttcttt cgttgcctgc gttgtatcac
    20101 ctatttattg gaacatcaaa aacacttgca atacttgctg ttgcaacagt tggtttatat
    20161 gggataggtg attgtatttt tactgggtta ttcagtatca atacgaatga aagctcttgg
    20221 aatctatcga cttggatcca taatataggt tctgggctag gctatgcagg ctttctactt
    20281 ttcccattgt tacttgttct gctttatcgt caaagtggtc aaggtacgct tagccatttt
    20341 tatcttgttt taacagttat tagtttacta attgcaggtc tttacggatt agcacggatt
    20401 ccgtcgatta gtcagtttgc cttctttaag caattgggct tctttcaacg cttaagtttt
    20461 ttctttaact atttgccgat gatttgttta agtttttttc aactacgaaa gtagaaaaag
    20521 cagtgtgaag ctgattaagt aaaagaattt ctctatgggt aaccattcgt gtggatgtgt
    20581 tcgactaaga atagagatga ggagagcgaa aagcaagtta gtcttaactt gttatgcgtt
    20641 gtgctaaatt tcaggtagtc attttttgaa tgaataagaa gaaaacttga aagagggtga
    20701 cttcatgtta gatgtggagc agatggaaat agacctttat aatattattt taaatcgaaa
    20761 tacaagagaa tgggaaagaa cacaatttga agaggcaaaa gaagacctag caaaaatgtc
    20821 gataaagcag gtgatagaaa aactagaggt caacttgcgt ccgctagcac tacgagataa
    20881 tttgacacca gatgcgatgg atttttattt aagaatcaca ggggagtcag cgagtgcaaa
    20941 ggcttatgat tatgccaaac ataagataac ttcaccctta taccaagaac gggcgatttt
    21001 tgccggtggc tgtttctggt gtatggttga gccttttgaa acaaaaccag gtgtaatctc
    21061 agtgttatct ggttatacag gtggagagac caaaaaacca aattacgatc aagtcagtgg
    21121 tggatatact gggcatgttg aagctgttga gatcatattt gatacacgtc aaataaccta
    21181 tgaagagctg ttggagattt attggcaaat ttcagaccct acagatgcct ttggtcaatt
    21241 tcaagatcgg gggaaacaat atcgttcaat tctatttgtt gttaatgaaa agcaaaggca
    21301 attggctgaa aaatcaagag aacaactgat tcaatctaac cgatttagcc gtcctatcgt
    21361 tacagagatt cgccaagcaa agactttttg gccagctgaa aatcatcatc aacaatttta
    21421 tcagaagcaa cctaaaagat ataaaaagat caagcattcg catcagcttc atttattttt
    21481 tcagcgacat agatagagga aggttgtggc gcaaagcgtt cagctccgac aaaataatga
    21541 gcaactgaca aaaatagctt ttcatatttt tggacagtta tgaattattt cgaggagttg
    21601 ctttgagaac accgaggaaa aggttgtggc gcaaagcatt cagcttcaag tcgcaaggaa
    21661 acaggaggta tgacaagtct tttgtcacaa ctcctgtttt tttactagcc tttatttcca
    21721 tgtgaaagag aattcgaatt gtagaatctt gatttttcta tggaattttg tagagaatca
    21781 tcttgataat taatagacac ctaatcgaat tccacattaa tgatgaacta aattccgtat
    21841 aaaagcgcaa acaataacta ta
//
LOCUS       DAFLWQ010000045        21457 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.046, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000045 DAFLWQ010000000
VERSION     DAFLWQ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.046"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            5..403
                     /locus_tag="L1V16_001701"
     CDS             5..403
                     /locus_tag="L1V16_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBN1276044.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            387..1082
                     /locus_tag="L1V16_001702"
     CDS             387..1082
                     /locus_tag="L1V16_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBN1276045.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1676..2563)
                     /locus_tag="L1V16_001703"
     CDS             complement(1676..2563)
                     /locus_tag="L1V16_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBN1276046.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2748..3587
                     /locus_tag="L1V16_001704"
     CDS             2748..3587
                     /locus_tag="L1V16_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBN1276047.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3783..4757
                     /gene="sgrA"
                     /locus_tag="L1V16_001705"
     CDS             3783..4757
                     /gene="sgrA"
                     /locus_tag="L1V16_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HBN1276048.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5055..5411
                     /locus_tag="L1V16_001706"
     CDS             5055..5411
                     /locus_tag="L1V16_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276049.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5414..6571
                     /locus_tag="L1V16_001707"
     CDS             5414..6571
                     /locus_tag="L1V16_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1276050.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6597..7037)
                     /locus_tag="L1V16_001708"
     CDS             complement(6597..7037)
                     /locus_tag="L1V16_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBN1276051.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7197..7703
                     /locus_tag="L1V16_001709"
     CDS             7197..7703
                     /locus_tag="L1V16_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBN1276052.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7871..9784
                     /locus_tag="L1V16_001710"
     CDS             7871..9784
                     /locus_tag="L1V16_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBN1276053.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9789..10790
                     /locus_tag="L1V16_001711"
     CDS             9789..10790
                     /locus_tag="L1V16_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1276054.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(10992..11198)
                     /locus_tag="L1V16_001712"
     CDS             complement(10992..11198)
                     /locus_tag="L1V16_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HBN1276055.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11844..12692)
                     /locus_tag="L1V16_001713"
     CDS             complement(11844..12692)
                     /locus_tag="L1V16_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1276056.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12691..13758
                     /gene="gnd"
                     /locus_tag="L1V16_001714"
     CDS             12691..13758
                     /gene="gnd"
                     /locus_tag="L1V16_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HBN1276057.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13760..14761
                     /locus_tag="L1V16_001715"
     CDS             13760..14761
                     /locus_tag="L1V16_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBN1276058.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFNVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMCEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14758..15042
                     /locus_tag="L1V16_001716"
     CDS             14758..15042
                     /locus_tag="L1V16_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBN1276059.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15075..15872
                     /locus_tag="L1V16_001717"
     CDS             15075..15872
                     /locus_tag="L1V16_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBN1276060.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLSSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15886..16719
                     /locus_tag="L1V16_001718"
     CDS             15886..16719
                     /locus_tag="L1V16_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1276061.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16737..17594
                     /locus_tag="L1V16_001719"
     CDS             16737..17594
                     /locus_tag="L1V16_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1276062.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17616..18125
                     /locus_tag="L1V16_001720"
     CDS             17616..18125
                     /locus_tag="L1V16_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1276063.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18162..18563
                     /locus_tag="L1V16_001721"
     CDS             18162..18563
                     /locus_tag="L1V16_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276064.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18675..19028
                     /locus_tag="L1V16_001722"
     CDS             18675..19028
                     /locus_tag="L1V16_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276065.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19062..19505
                     /locus_tag="L1V16_001723"
     CDS             19062..19505
                     /locus_tag="L1V16_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBN1276066.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19522..20607
                     /gene="uxuA"
                     /locus_tag="L1V16_001724"
     CDS             19522..20607
                     /gene="uxuA"
                     /locus_tag="L1V16_001724"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBN1276067.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20600..21313
                     /locus_tag="L1V16_001725"
     CDS             20600..21313
                     /locus_tag="L1V16_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBN1276068.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         7386 a         3292 c         4475 g         6304 t
ORIGIN      
        1 agagatgacg atctttgaaa cggttgtaac agatgttggt atagaagcag aagtattcag
       61 gaaagaaaaa ataatgattt tatttggaga tgaagcaccg gaaacattaa cagattattg
      121 ttataagatt gaattgaatc aggtaagaaa agaaataact tgtgatatga agctctgttt
      181 tgataaacaa atgtatgtaa tcacagcagt aggagatgtt gtccaaacta atttgaatga
      241 attaggacat atcacgataa aatttgatgg atctcatgag ccggaacttc caggaacaat
      301 gtatgtagaa gataaggaaa tgccgcattt aagaaagggg acaatcatta aaatcgatca
      361 agaggatcag aatgggggaa agctatatgg aaatcatgct tgatacagca aatacaaaaa
      421 gtatttattc ttgtcaacag tttttgaatt taacaggcgt aacaacaaat cctacaattc
      481 tgaaaaaaga aggagcgtca aacttcttct cgcatatgaa agaaatcaaa aaaataatcg
      541 gacagattcc tatccatatt cagacaatag gaagaacgga agaagaaatg atagaggatg
      601 ctcgagttat catagaagaa ctgggaaaag atacgtttat caaggtgccg gtgaatcaag
      661 caggccttca agcgatcaaa aagttgaaaa aagaaggtta tttgattacc ggtacagcta
      721 tttacacaga attacaaggg tatttagcta ttaataatgg agcagattat attgcacctt
      781 attataacag gatgcaaaat caaggcattg atgctatgaa agtgattgat tcgttgcgga
      841 ctgagatcga acgtacgcaa agaccaacaa aaatattagc agctagtttc aaaaattgtg
      901 aacaagtcac tacagccatt cgatctggag ctcatgcgat aacgttaggt aaagagctac
      961 tagatcaagt attagagatg ccctcgattg ataaagcagt gaggggcttc caagaagatt
     1021 gggtgcaaac tttccaagca gaaacgattg gtgaactaaa aaaggtcgct gattacttct
     1081 gaatcaattt ctccataaaa taaacgatag ccttctcgaa aactcgagga ggctatctga
     1141 cgattcaata ttcattaatt taaagtttgg gtgactatta ctaactatta cttatttctc
     1201 atttaaacga tgtattccct aacctctaat acatccttgt aactctgaag ttacgccagt
     1261 tttgaataaa tttcataaaa acaaatgaaa agtgtcgcat aaaaatatct ttcgtgtttc
     1321 tctagtataa cagaataaga agaacaagtc cagaagggat atttttagtc ttttttaaaa
     1381 taacttttca gtcgagtttg agtttatgat agttgttttt gaagcgatac ggcaagtgaa
     1441 aaaataggga agcatgaaag aatctactta atggcgcatt gattcatgtg atagaaataa
     1501 aaaacttttt taaattatat cctcatgatt gtaacaaatc cagtgatttg ttttggtaca
     1561 aataaaaaaa ggccccgatg aagttgtggc aaaagtggtt tgcctcaaaa ataagaagga
     1621 atttccaaaa atcacttctc aaattttgcc acatccccaa ttgggtcaaa tttgtttatt
     1681 tgaatatatt ttttacataa ggatctttaa tagttacatt gtcttttttc atcactttac
     1741 ggattgtttt atccatgaat tccgtatcaa gagtttttgc ttcggtagca attttttcta
     1801 gctcagattt gtatttgtct ttattagaac ctttatcctg tttttttacc atttttacta
     1861 gataatagct ttgctgataa gtcgttggat ctgttacagg aatgatatca gaaacttccc
     1921 cgttttttag tttaaatgct gcttttttta cttcagtagg aatctctgga ttggttgaat
     1981 caaaattcat ttttccatca gtttccttta atgttttatt ttttccataa gcttgaacaa
     2041 gcttggagaa attttctcct tcatttgctt ctttttttgc tttatctgct tcttctttag
     2101 tcgaaaatag aatgatctgt gtactaactt ctggatagaa ttctttccaa gcagtgtcta
     2161 gatctttatc tgttaatttt acattggctt tcaaaccgta ttggaaagcc agcatctgtt
     2221 taaagagttt cttatatgtc tcttctgttt ggccaactgc ttttaattgt tccttgtagt
     2281 ttggaccgag ttttttgatt tgttcattat attcttttgt tacttccttt gaagaaatct
     2341 cttttccgta tacatcatca aatgctttga agacaatcat tttttttaat agtgtttgat
     2401 tatttgattt aacttttggg ttatcataaa aatcctgaac tgtaagtgtt ccacctttaa
     2461 acgttgcaat cgtttcattg gacttgctac aacctgagaa tagtaaaatt gcacatgctg
     2521 aaaggcacat aattagtagt tgttttttca aaaaatttcc catcctttcc ttattaaaaa
     2581 cagtctaaca gaagaattag ggagacagtc tttcattttc gtaaggttgc tgtagatatt
     2641 cttagttcgt aaaaatctat tctctctatg atggagaaca tttacatagt tttcacgaga
     2701 caagaaagaa aagggttgtt aaacttaata taaaggaggg atgaaagatg atcaggatta
     2761 ttcggttgat tggatctgtt ttaatagtct tagttggttt tgttttagga attcttgtca
     2821 ataatgcact tgcggatatg tttattggaa atagtgaatg gattggagca attgccggta
     2881 cggtcggaca tttagctgtt tttttactag ctttatttct tgctagtaag gtcgaaggaa
     2941 aaagaataga agattatggt gtttctgttc gaggaaaaga ctgggggtat ttagcgggag
     3001 gtctcgttgt tggaattgga gtgtttctgc ttattactag tccattatat ttgacggggg
     3061 cgtatcggtt agattcagga aacgcaaaca ttgtgccgct gataacgagt tttattttat
     3121 ttattgcagt gggggcatca gaagagcttt tattccgtgg cttttttcag catcagatgc
     3181 ttagatttgg tccgttaata gcaatgattg gatctgctgc attatttgct cttttgcacg
     3241 gattgaatcc taacatgaca tttctggcag ttttcaatat ctttttagca ggttgctttt
     3301 tcagcgcact tatctacagt acaggaagtt tatttacggc tattggtgct catattactt
     3361 ggaattggac acaaggagct attttgggta taccagtcag cggaacgcaa gaacaaggtt
     3421 ttttctccac tctgatccaa tcgcaaaata caataattac tgggggaaac tttggggctg
     3481 aagcatctat atcaactaca ttattcttgt tagtcttgat tgttggtttg ttactctatg
     3541 catataaaac aaagcggatg aagaaataca ctgctgttta tcaataaaag atgaagaaag
     3601 caaggctgat atcggtcttg cttttttaag tctgtcattg attaaacgaa aaagtaaaca
     3661 aattcaagcg aatacacgac atcttttgtt agattttcac aactgactgt cgtgttctca
     3721 tcattttcat tttatataat tcctttatca aatagaaggt aattatatgg agagtgatag
     3781 aaatgaagaa aacagcgacc gtattatttg ttattcttgg gctgagtata attgcagcaa
     3841 tgattggaat cagtacttct gcaaatgaac gggcaaatga gaatctttca tttactgtga
     3901 aaactgatcg gattgtttat gacatgacac aacaagtcat tactattcca gtcaaaccaa
     3961 acaaaagcgt gaatgctagt gatgtacatg ctgttctaac atatggttgg gatggtaatg
     4021 gaagttcaga aaaagttatt ggggaagttt atttaaaaga cgtacaatgg accgctggta
     4081 ttgagtatac aataatgatt tctgcagaac tatcgattga tgagatcaag agtaaagata
     4141 aagttgattt gattgttttt tatgatggac agatgacgat cacggagaat ttgaaaccaa
     4201 gcagttggac agttgttgga ccgccaagca gtacggatag cacaagtagt gaaagcagta
     4261 cagaaaacac gagcggtgaa agcagtacag agagtacgag cagtgaaagt agcacagaaa
     4321 acacgagcag cgaaagcagt acggagagta cgagtagtga aagtagcaca ggaagcacga
     4381 gcagcgaaag cagtacggag agtacgagta gtgaaagtag cacaggaagc atgagtagtg
     4441 agagtagcac aggaagcacg agcagcgaaa gcagcacagg aaaagtaaat aatgaacttg
     4501 atttggtacc tatcatacca actaaggaac aaaagagaaa tgcagggagc aacctaaaaa
     4561 gtgtgctaaa acagcctgat tttgtttctc gtggaattga tcatcaagaa aaagcgaaag
     4621 aaacagataa tagaaaaagc gatttaccag aaactggtag tagaaccttg aacaagctaa
     4681 ttacatggat gggtgtgtta ctcattttga ttgtaggagc aagctatttt cgttctctct
     4741 tccatcgagt gaaataaaga ataaaagcaa cagatctaaa attgaataaa acgatagatt
     4801 tttgagtgaa tatttcattc gagagtgctg tattgcctgg cgaagttgta gctttgccag
     4861 atctattttt gtttactaac atatttgaga aacaggaaat aacaggaaca caaatggaaa
     4921 ataagagcaa gaataattga caatgcacac tgcgcatggt agtatctctg aaaaatcagt
     4981 aacgaatcta tttgtacgtt attcatgtag ctgtcggaat aagtctaaat aatagataaa
     5041 aaggagtatg tactttgttt gaagaattta ttgatatcaa tgaaaggcaa gtatatcaat
     5101 ttttgaacta ttgttatgaa agagacgaga aattatatgt ggtgaaggat atcgctttag
     5161 atctaaacta caccctggct aagatgaatt cggtgattca acaagcagaa tcgttttgcg
     5221 aaaggtatcc agaatataaa ttatcttttc tttcagaaaa caagatgata aaagtcgagt
     5281 tttcttctca gtttttactg agtaaagttt attctatact tttagaggga acgattggtt
     5341 atattttact ggattcactt tacaaaggta cttatcaatc cttagaaaat cttagtcaaa
     5401 aaattatata agtttgcgta cgattcaaag aaaattaaga gaacttaata ctattttgaa
     5461 aaactatcat ttatcttgca gcttgaaaaa aggtaatccg atagaaggag aagaataccg
     5521 tatccgatac ttttttcact tgatgtattg gcagtcattc gacgaaaatc attctgatat
     5581 attatcaagt ataaaaaata aacgtcaact attagaaaaa tttgcgaaac atgcgccata
     5641 tacgcgtagt atagatagaa agaaatggat cagcctacta agaatttcgt tgcaacgaat
     5701 gaaacaaggc cactcgatta cgtatgtccc agaagagatg aacaaatttg tgcatccatt
     5761 gataacaaaa gaagagttta cgcattacat actagagcct ttttttgaag caaacttctg
     5821 gtcgatgaat cacatcactc caacagagca agcttacctt tattttatgt ttggtgtaat
     5881 gaacacctat ttggaagaag atttgttgga tactccagat aaagtacaag aaagttgggg
     5941 ctggattgaa tcgtctattg tagaaaattt tgaaaaaaac ttcaagattt gttttacaac
     6001 ttcagaaaaa aattatctat atgtcaattt ggcaatgatc catttgtatt caagggtttt
     6061 tgggacaaaa aagaaggtgg atgcttttgg aaaatcagca gaagacagag attttcagca
     6121 tatatttcca gtgatgtatc caatcatgca acagtttttt agtggggtag ctcgcagaat
     6181 tccagagctt aatacttatt atgaaaagaa cagacggttg atttttcaat actgtatgtt
     6241 agtcagggat atttttataa aacacgaaca acctgtcata ttctatattc aatcaaagta
     6301 tggtaaaaca caggaattat gggcaaagaa aaggatatta tctatgactg aacgcccaat
     6361 aaaatatagt gcatccgctg atcagttacc tgatattgtc attagcgatt atcctatcga
     6421 caaaaaggca tatgatcaaa cgaatacaca gatattttac tggaatggac aacctacaaa
     6481 aaatgattgg gcgcgtctga aagctgaaat cataaaaatc aggaatgaga aaaatagatc
     6541 catattggaa aaattggatt tcgttaatta agaaaagcag attgtttatg ccaaaattaa
     6601 gacattgcaa aaagattatt ttctttaaaa tcgacaagat gaccagaaag caagagttcg
     6661 ttgagctctt gctttctttt agttttagaa aggaacatcc tgattttatc ttcgctaaat
     6721 ccagtcaaaa gttttgcaga ttggtcgtag ataatcggtt ttttcaataa agaaggggat
     6781 gtacgaatct caatatatag ttcactcaaa ctgagttcat ctattctgtg aacaagattt
     6841 ttataactaa tagaatgagt agagagcatt tcggtcacgc cgttgtttgt caattttagt
     6901 aagtggataa attcattttt ggttagtggt tgacgaatta agttctgttc gataaacggt
     6961 atatcatgga cgataagcca acgttttgcg cgtcttgaag acgagcagcc agaacctgta
     7021 tacaatttaa tcatcataca ttcctccaat agctaagtat ttatgaaata ataacatgaa
     7081 gaaatagtcg aaaagtgcca tttagaggtg taaaataaga aaatgttgtc acgtataatg
     7141 gaactagcta gataagaaat actattaaat caagaaaaaa gaaagaaggc acaagtatgt
     7201 caaacacagc cgacgcaata gtagtgatcg atttacaaaa aggggtatgt tttgattctt
     7261 cgccgataca cgaattagaa acagtgacag cattagtgaa taaaagaatc aaaacatacg
     7321 aaacgattgg gaaaccagtt attttcgttc aacacgaaga tgctcaatta gtgccacaaa
     7381 caaaaccatg ggagctattg tcggaattat ctattcctga gcacagttat tttgtgagaa
     7441 aaacccatgc gaattcattt tataagacta atttgagtgt tttattaact gaattggact
     7501 gtcattcgat cgaattatgt ggggcacaag cagagtattg tatagatacg actgtgaagt
     7561 ttgctcatgg attaggatac cagcttatga tgtgtagagg agcaacgaca acttatgata
     7621 atccttttat gaaagcaaag gaaacaatcg ctttttacga gaaaatttgg gataaacgat
     7681 ttctgacatt tttggagcaa taagttgttt cttcgtttaa aaaaagcaga atggatactg
     7741 gtttatccat tctgctttat tacgtaaaat gagaaaataa tcctgttcta tttttatggg
     7801 ataaaccatt tattttttgt ataaaaaatg tttgcgttta catataattc tcctagaaac
     7861 ataaaaagga gtgaatagct tgagaacaaa acaagtatta aagggagcgt tggtcatctt
     7921 atttgctgta agtacaagcg tcccgcaatg gacagtatat ggagagagca tttcttccga
     7981 atcggaatct cgggaggtag aaaccacaga aactactgat gctggaaatg aaacgaaatc
     8041 gagtacttca caaacagaaa caaatactga aacaacggtt gagacatctg ttactagcac
     8101 agatcaagaa acgaccgcta ccacagataa ccaacaaaca gaagaagcaa cagctacaaa
     8161 aatgtcaaac gacgaatcct cttctgctaa agtaagtgac aaagagaatg ggacagaaaa
     8221 tgatgatatc ggtaaaggtg aaaatttcaa tggtaaagaa tatttgaatt acttcggtaa
     8281 acagatgaca gaaatactta atggaccaac agaagacatc aagtcaaaat taatagagtt
     8341 attagtcact gagcttgctg ttaatgatta tggtgtagat aaagagatta tcaaacatct
     8401 gattgctact tatctattgt acgatatcgc ttttgcaaaa aacagtgtgt tgatgtcgat
     8461 gcttggaggt acagatgatg ggacaacgcc tacagaaaac acaggcttct atccaaatac
     8521 aaaacaactt catcaaactg tactaaacaa acaagatggc aaaatgatgg atgtatatgc
     8581 atattatgtc gatcaaggtt cagataaaac agtcatgatc catggcggat ttcgagggaa
     8641 ttggaataac gggatcgtta cagaagaata caatgatttt tataaggccg ggtataattt
     8701 attatttgtt gattccagag cgactggtaa tagcggaggc gattatgtga cctatggaca
     8761 atatgagtca gatgacgtcc tttactggat aaatcaagaa gttcgagagc ggccatctca
     8821 aaagatttta ctttatggtg gttcgatggg agcagctacg atgatgtctg tattagcgaa
     8881 agatattcct gtcaatgtca aaggaattat tgaaaattgc ggatttgcat caattgatga
     8941 acaactacgt tttacgtaca gccagacagt agcccccgca ctaccggatg ccataaaaaa
     9001 tcagttagac atcattgggg atcaagagca tgaagattta tttatgggcc ttttgaaaca
     9061 atactatttt gatcaggaga tgcatttgga tacaaaagct gctctaccta cgattggaat
     9121 gtcagattca ttgcctaaat tgattatcca tggaacagca gatgatgtag tacctgtgtc
     9181 taacgcgcaa aaattatatg agttatcagg agggtataaa gatcttttat tagtagaagg
     9241 agcagggcat ggaaaggcac aggaagttga ccatgctgcc tacacgaaac atgtaacgga
     9301 ctttttgaaa gtagtgttcc atgatcagat aaacgtaaag tatgtggatg aaaacaataa
     9361 aagtctactc aaagaccagg acgaaatcca gctttacgga gcttatggag aaaattatat
     9421 gacagagcaa aagacattcg aaggatacga attagcaaat gttgaaggac cgactgaagg
     9481 gatttttaat gagacgatac caactattat tttctattac aaaaaaatcc cagtagctcc
     9541 accaaaaaag caagatccga cagagaatgc agacaataag ggaaagaatg aacctcgaga
     9601 ggatcaatca agtgatgata cgcaaccgat tcagatgaca gtgaaagtac aaaaaaagac
     9661 agatgcaaaa aaaagaatgt tgccgaaaac tggagaaaag aaacattcgc ttctcattta
     9721 ttcaggtgga tttttatctg ttagcacgat tatcacatgg atttggcgaa gaaagagagg
     9781 gtaaatgaat gaaatggttc aagcgaatag tgattgcagt accagttatc atcgtagtta
     9841 ttttagtcac tgtatttttg attaatcaaa tcacaccaaa gccgattagc ttgcttgtta
     9901 gaaaacaatt tgacacaagt gaaaaagaac aagtatatgc ccgaccagat gatttccagc
     9961 aaaaaatcga acaaatcgat ataaaaaaag aaatatccta tccttcaaag tacaaaaata
    10021 ataatatgga tatctacaca ccgaaagtgg aaaagaaaaa attaccgatt cttttctgga
    10081 tgcatggagg cgcatatgta ggaggggata aaaatgattg tcgtgattat ttggaatatc
    10141 tatgttcaga cacgcagcaa atcatcgtaa atatagatta tgaacgatca ccggaagcaa
    10201 aacatcctac accagttatc caattgaacg aagccattca agcagctaaa aaagagataa
    10261 aagatcaagc agattggtcg aatatttcga ttggtggaaa ttcggcaggt gcacaaatta
    10321 gtggagaata tttgttagca cttcaaaatg aagaaattaa aaaagctgat catcttgatc
    10381 cgactttgga gaacaagcag attacgaagt ttatttcttt gtctggtctg ttggatcctt
    10441 ctgcacttac tcaagtaagt gataaaatct ctagctttct ttatgaaaaa tgtggatggg
    10501 cttactttga taataaggac tttgaacaat cagagaaggt caaaagttta gccttggtca
    10561 gacatgcgga tcgttggacg caaaacacat tcttaacgga tggaaataca aatacgttta
    10621 cgaaacaaat ggaagaagta acttctgtat ttgagaaagc gggggtgaaa gtcacaaaag
    10681 tagattatgc ggagaaaaat gctgttttga accatgaata tcagtttgat ttcagcaata
    10741 aacaagcgca agaaacatat caaaagttag taatgttttt caaggagtaa agtcttatga
    10801 tgcaaaagag gttgtaatct gtcacttagc tccaagtcac aaggagcaat ttcaataaac
    10861 aagcttttca tggtttatga atattgtaac ttgtgactga ggagttagag atggcaaggg
    10921 gcacctttta ttcgaaattt gggaatatca cacgattatt gtcacgatct cttttacgta
    10981 aattttataa gtcagatttg ttgttttgat cgtttaaaaa aagcaacaaa tccgaagcct
    11041 gcggaggcaa gaagggacaa aaagccgagt ggtaagcaaa agaatgctgg ttccactaat
    11101 attccgttgt tattgatata aggctgggaa caaagatgaa tagcaaataa aatcaatgca
    11161 ctagcgaaaa aaagcaaaga aatatggata gctttcataa gcagcacctc cttttttata
    11221 attgtatgat aaatagatta agaatctata aatgtgacaa gtttgttagg atgtgaataa
    11281 aatgatcatc tagcgaactt gaaacaaaga tggctaatga taagcaatta atgattcagc
    11341 aatcagatag gtacaaagtt taccatcata cgtctagacc aataatagaa aatatgggaa
    11401 tataatagaa aagatttagg atacccccaa aagaatttcc ccaaaaattc gatgtatcct
    11461 aaactttttt attttacata acaatcatat caactgtgaa ataaaattac aaatgataac
    11521 ctaaaatgag gccaaaagcc agtgttatca aggaaatact taattcacca aaattttttt
    11581 taatttttta gaaaataaga aacaaaaata ataaaaaaaa gaaaagataa attttttact
    11641 actgtatact aactttgtta tcgcatctaa caagtaactc gaataatacc aatacaacct
    11701 tctccaaaga tgcgatgaca tacgttctaa cccaccgact attgatgttc tgtaccaccc
    11761 ttgcagaacc aaaaaagcca ctaccaaata tttggtagtg gctttttttg ttttatggat
    11821 ttttcgcttt ttctgttatg gtgctattct ttgatttcag aaatagtatg tcgaacttta
    11881 gcgatagaac gacgtgattc tttttcgttg taaaacatca aaatcacata tagagagtcc
    11941 aaaatgctta gttgagaaat acgggaagct aaagcttcag atcggaattc tgtttcttca
    12001 gaaatagaaa taaaaacgac atcgccaagt ttagcaaggg aagaattagc ttggctagta
    12061 ataacgattg tttttgctcc agtttttctt acggtttcag caatatggat tgtttctttt
    12121 gattgccctg tgtgagaaat caaaacagca cagtcttttt ccgtcaataa agaagcttcc
    12181 atcaattgaa tatggtaatc cgtgctgtga gaagttgcga taggggaacg caaaaattta
    12241 tgataagcgt cagttgctac aatctctgaa ccgccaacac cgaaaaaata gacacgttta
    12301 gattcattga taatagtagc cgcttttttt agatcctttt gttgtaacaa cttttttgtg
    12361 tcatttaaag ttgaaatact agactcgaac accttttgcg ccatagtgag ctcagtatct
    12421 gttttctgaa tattttcgtg gatagaaata gcagatagat cattttcttg gatcaacatg
    12481 gccattttaa aatctttaaa tccattataa ccaagttttt ttgtaaattg aaaaaaagta
    12541 gagtcagcaa tgcccagttc acttgctaaa ttgctaatag gactatgact tactttgctt
    12601 ggattttcta aaatataatc ggcgatagcc tgttcttttg ggctgaagtc gttgtacatt
    12661 gttttgattt gtagtcttat ggagacgctc atgagaattc ctcattttca taataagatt
    12721 atcatttttt ccgttctcat taatgttaaa gatacaagga gagtaggaaa aaatcaaaca
    12781 aaaaatattt ttgtaaaatc tatttacaaa aaaatttttt tgtataatga gggtataaga
    12841 aatggaggcg ctatcatgga aattggtgta attggtttgg gaaaaatggg attgaattta
    12901 gctttaaact taaaagagca ccatcacaaa gtacaaggac tcgacatttc aagtacagct
    12961 gttagtcagg caagagaaaa tgacattcct gcttatcaag agatctctga atttctagct
    13021 acttttgagc agaaaaaaat catctggtta atgcttcctg ctggagagat aaccgaaaac
    13081 atgttaagaa aactttttcc aaaactcgga ccaggagaca ttattattga aggcggaaac
    13141 tcttattata aagattcaat ccgtcgagca gaagagtttc agaaaaatga aatcggttac
    13201 ttggattgtg ggacttctgg aggaatcgaa ggagcacgac atcaagcctg cttaatgatt
    13261 ggaggagata aagaaacttt tctatccgtg gaacaattat tcaaagatgt agcaattgaa
    13321 agaggatatc tgtatgctgg tgcatccgga agcggacact tcttgaaaat gatccataat
    13381 ggaatcgaat atggaatgat gcaagcaatc ggtgaaggat tccaacttgt acaaaaaagt
    13441 gagtatgctt ttgacttgga acaagtcgca cgtgtttgga atcatggttc ggtgattcgc
    13501 ggctggctga tggaaatcat ggaagatcag ttaaacgaac atcccaattt aagtaattat
    13561 cggggaatcg tttctgcatc aggtgaagca aaatggacgg ttgaaacagc gctagaaatg
    13621 gctgttccag ttccagtaat tgcaactagt ttgttcatga ggaatctttc acaggaagaa
    13681 gatagttttt cagcaaaagt agtttcagca ctaagaaatg ggtttggcgg acatgaaata
    13741 gttgaaaagg gtgagtaaaa tgccagatta tcatatagca atcgttaatt ccagcagttt
    13801 cggaagagtc tttccacacc acttggaaag attaaagtca gttggagacg ttcatttctt
    13861 taatgttgat caagagattc caggaaaaga actagcggag ttacttaaag gattcaatat
    13921 cattattgca agtgttacgc cattttttcg acgagatttt tttgaaaaca aagatgaact
    13981 gctattgatt tcccgacatg gtattggtta caacaatatt gatttaaaag cagcaaaaga
    14041 acaccagaca atcgtatcta tcatacctgc tttagttgaa cgaaatgctg tagcagaaaa
    14101 taatataact aatttgttgt ccatgcttcg acgcacgaca caagcacaag caagagtcaa
    14161 ggacgatcga tgggaagatc gggcggagtt cgtcggtagg acgctgttta acaaaacagt
    14221 tggtgtgatt ggtgcaggaa ataccggaag cggagtaatc gaaattttgc gtaacggttt
    14281 tcgctgtgat gttctagctt atgatcctta caaatcagat ttatacatcg aaagctttgg
    14341 tgcaaaaaaa gtagaacttc aagaattact ggaacaatca gatatcattt gtttatgtgc
    14401 gaatttgaca gaagagaact atcacatgat ttctgataaa gaagtcgatc agatgaaaga
    14461 aaatgtttat ctatctaata gtgcaagagg cgctctagtt gatgaagaag cgatgattaa
    14521 tggtctgaaa agcggaaaga tcgcaggata tgccacagat gttttagaag aagaaccggg
    14581 acgtcaagat catccgtatt tagcgtttga acaagtagtg attacgccac atatatcggc
    14641 ctacacaagg gaatgtttag aagcaatgtg tgaaaaatgt gtcagagatg tcgaacagat
    14701 cagtcagcac cttcttcctg aacgttctgt ccagacaaag agcaactata taaaaggatg
    14761 atgaagaaaa tggtgaacgg tttaaaagtg aaaacaggcc ctcaatttta tttatatgaa
    14821 gaaggtggta tttcaaaagt ttctgatctc ttgaaatcat acggcgcgaa aagagtactg
    14881 gtcacccacg gaacggtatc atgggaaaag gcgctaccta aattagtatt tttgaatgac
    14941 gaaacgattc aattttttta tcatcgttat tctggagaat gtagttatgc tgaagccaga
    15001 cgaatagcta caatcatcaa aaaaatgaaa tcgatttcgt agttggcgtt ggcggaggaa
    15061 aactgaccga tctagtgggt tatagtgcca atcttgcaag aatcgatttc ggagtcatcc
    15121 ctactttagc tagtaattgt gctccatgga cacctcttgc tgtcatgtat aaggagaatg
    15181 gacaagcaga agggaaaaca gaacactttt acagacaagc tgcttttttt ataacagatc
    15241 cccaattagt gattgattcc cctgttccat atttcattgc cgggttagca gatacactag
    15301 caaaatggta tgaatctgag ctcatcttag aacaagattt tttgcaagat gaatcatttt
    15361 tgaagctagc acaagatact gcgaagatct gcaaagaaga gattttgaat cattctgcta
    15421 aagcaatcca agatatggca caaagaaaac tgtcatcgga gttcaaacag ctttcagaga
    15481 ttatctttgc tgttgctggt ttagttggag gattaggaga taaatacgca agaaatgtgg
    15541 cagcacatgc tatgcatgac gctatcagta aatatattcc ggaaagccat cgttttctac
    15601 atggagaaaa agtagcgtat gggattttct atcaactggc actagaaggt cgctgggaaa
    15661 aaatagacga gttatatcct ttgtatcggg aattagaact gccggtttct ctagaacaaa
    15721 tgggattatt tccgaaagat aaacagataa tagataaaat ggctgaattt attgattcga
    15781 aagagaaagt gcatttgatt cctatagagg taacacagaa atcactgata cagtcaatga
    15841 tggaactgga aggttatatc agaaagatct gaaggaggag gacacatgga aacattaagt
    15901 gtagtacaaa gtttgttgat tgctttatgg gtagccgcgg ttatgtcccg ctggttaggt
    15961 ggaggagcca cgttgacctt acgtttttct cctttgatga ctggattagt cgtcgggttg
    16021 atcatggggg aagttgcaca agcgatgatt gttacagccg ctttgcaaat gatttatatg
    16081 ggggtttttt ctccaggagg atcaatgcca gctgaaccat ctattgcagc agctatcgca
    16141 gtaccagtcg cattattagg ggatctgtcg ccagaagcag cgattgccgt tgcggtgcca
    16201 gtcggattgc tcggaagtta cttgtatcag tttcgttttt tcatcaatac ttttttaggt
    16261 aaatatacag acaaagctgt agaagatttg aatacaaaag ctatggcccg atcaattatt
    16321 ctttatccaa cggttgcctc atttttatta ttcgttccgc ttgttttcat tgctttatat
    16381 ttaggggcgc cattgatcgc tgatgtaatc aaagctttag agggaacagt cgttatccac
    16441 attcttgaag tagtaggtgg agggttagcg gcaatcggta tcgcgacaac tgtatacgtt
    16501 atcggtcgaa aagattatct ggtctttttc ttccttgctt attttatgag tgttgttttg
    16561 aaatctttag atattacgat ggttacttat gccatttttg ggattattat cgctttgatc
    16621 tttgtccagt cgcaaaaagg gaaacaagta cagcctgcca caagcaataa caattcagca
    16681 tcttttgatg acgaagatga ctatgatgac ggattttaat ttaggaggaa tgggaaatgg
    16741 ctgaaataat ggataatcaa acaggtgctc ctgaagaaat cacgaaaaaa gatgtaacaa
    16801 aagcctatct gagatggcat tttgcaaacg aaattcctca ctcttttgaa cgttacttgg
    16861 cgccatcact actatacgga atgatgccaa tcttgaaaaa actttataaa gatgaagact
    16921 ctttaaaagc agcatataaa cggcagttac tgttcttcaa cactcaatta agctggggtg
    16981 gcggtgtgat tactggccta atgtcttcta tggaacagca aagagcagaa gaagagtatg
    17041 aagaaaaaga gatcttgatg caggatgact tgatgtataa cacgaaagcg ggattgatgg
    17101 gggcactagc aggaatcgga gatgcaatcg attcaggaac cgtccaatat atttttatcg
    17161 caatcgcggt accttgggca caacagggaa gtcctttagg cgcacttttt ccttttatct
    17221 gctttgggtt gtatcaggtt ttactagggg tatttttcgc aagacaagct ttcactatgg
    17281 gccgtaatgc tacaggccta aagcaaaaca ctggtgttca gacagcgatt gaaatgctat
    17341 cagttttagg gttgtttatg atgggggtgc ttgcgggaaa ctatgtaaaa gtagaatctt
    17401 cattgaaatt tgcgatatcc ggacgtgagt ttgttatcca ggaaattctt gatcaaatcg
    17461 tgccagggat attaccttta gctgtcgtaa tgggtgtgta cttgttctat acgaaaaaag
    17521 gattgaaagt cacacaagca ttattatggc tgactggaat attaattgtg ctagcaggaa
    17581 tcggtatttt ataaaaagaa gggaacgtga ataagatggg tgtagtcaat ttagcgcgtg
    17641 tggatgagcg tttgatccat gggcaagtaa tggtaacgtt atctcaaaaa agtggagtga
    17701 attccatttt tgttgtagac gaagttgtag caaaagataa atttatgaga gatctttaca
    17761 aaaatgcagg aagccgtaca ggacaaaaaa caattgtcat tacaccagag aaagctaaat
    17821 tctattggga tgaatatcaa tttaaagaat acaattgtat tttgatcgca aaaacagtcc
    17881 aaacgattta cgacttagta aaacacggaa tccccatgga agaattgaat attggaggga
    17941 ttgctcaaaa aaatcctgat acagatcttt tagtgacgaa atctgtttat ttaaataaat
    18001 cagatgctga aaaattgaaa gaaatgaatg aacaatatgg cgtaaagaat atttattttc
    18061 aagccactcc atctgcacct aaaacaggat taaaagatgt attgaacaag tttgatttgt
    18121 cataaacaaa tgcttagaaa aaagataaag agggcgaaaa aatgaagaag aacgagctgt
    18181 ttcgtgattg ggaatttcgt tatcgctata tttaccgtaa gcgccgtaca aaaaagagta
    18241 aacagcgttt tctttcagca ttagtatcag atatttacag tatgagaaca gatgtgacag
    18301 tcattgctta cgatacgcta gcctaccgat caaaaaatat ttatgttgga gatatcgaaa
    18361 aagcagagaa agttatctgt acttattacg atacacccgt tcatgcatta ggaagttatt
    18421 tcatgtttga ttggaaagac caaaggaaaa aaacaatcta ctctatatta ttgtccttca
    18481 ttttgttgtt cagtttaggt tggtggggaa tgatgatata taacaaaaat cctcatcacg
    18541 tattcgatct gctatccgta taaacaggta tcactgtact agcatttggg agctactttt
    18601 tcttattggg aaaagcagct cgcggatggc ctagcagaca aacttttatt cgaaatactt
    18661 catccatatt aacgatgcta gaaatgatcc gtacgattga tgatccgagt gtagcgtatg
    18721 cgtttgttga tgaaggctgt tatggagaaa agggcttaga cagcgtgaga tcgggtatga
    18781 aaaaagaggc tattcttttt tatctagact ctgttggggc agatacaccg ctacagtttt
    18841 cgggaaatta tttttcaaat aaagaacagt ggctgaaaca agttgataag ttgaaagaaa
    18901 aaaacgtcaa ttatattttt agtgcaagaa aaaagcaagc gcagttcttc tatttgacca
    18961 aaacagattt acgagggaaa acatttaatt ggcaaaatgc caatcagatt attgctcttt
    19021 ttcgataagt aaaaagtgca aaacaaggag tgagaagact aatgttggaa atcatgatcg
    19081 ttacacatgg taagttgagc gaaggactga aagatgcggc ggaagtaatt gtcgggacat
    19141 cgagccatat tgaaacaatg tgcttagagt ctggggagga catccaaaca ttcggagaga
    19201 aggtcaaaga aaaattaact atgatcaaca cagcagaacc catgctagta tttgttgatc
    19261 taattagcgc aagtccgtac aatcaagcgc tcttggcagt caatgaactg actgaagaaa
    19321 agaaagcagc cacttatgtc atagggggcg tgaatctgcc aatgttgtta gaagcaatca
    19381 atcatcagat gcttcacaca ccgatagaag aagcggtgga acaaattgtc aaacaaggaa
    19441 aagataattt aactgtttgg catgcttcag cggaagaaaa aaaattagat gaggacgatt
    19501 tttagaagga aggctgaaaa gatgaagtgg ggatttagat ggtatggtga aaaaggggat
    19561 tcgatcccat taaaatatgt tcgccaaata ccgggaataa atgggataat tggaactttg
    19621 ctgactaaaa tgcctggaga tgtttgggag atttcagaaa ttgaggagtt gaaagcatct
    19681 gttgagagcc aaggactgga actgcttgga attgaaagtg tagcgatcca cgatgcaatc
    19741 aaggcaggga cagatgaacg agattactat attgataact atatacgaac aatcaaaaac
    19801 ttgtctcgat gtggggttcg attgatttgt tatagcttca aaccaatttt tggatgggcg
    19861 aaaactgatt tgtttaatga aaacaacgat ggaagctatt ctcttttata cgatcagaaa
    19921 atcgtcgatc agatggagcc aggagaaatg tatcaattga tacacagcca gtcaaaggga
    19981 ttcaaattgc cgggttggga agaagaacgg ttgaaaaaat tcgctcagct ggaaaaactg
    20041 tatgaaggaa tgaccgaaga agaattattt gaaaatctga cttatttttt agaaaaagtg
    20101 attccagtgt gcgaaaaagc agatgtaaaa atggctatcc atccagatga tccgccatgg
    20161 gaactttttg gttttcctag agtgacgaaa aatcttggcg acttgaagaa aattctaaat
    20221 gcagtagatt ctccatataa tggactaacg ctgtgcacag gatctttagg ggcaaatccg
    20281 gaaaacgatt tagttgaaat catccatgag gtaggttcgc gcatccattt tgtccacttc
    20341 agaaacgtgg agtttttagg agaaagaaag ttcaaagaaa cggcacatcc ctctacagaa
    20401 ggctcccttg atatgtatca tattatgaaa gcgttggtgc aagaagggtt cgacggtcct
    20461 atacgccctg atcatggtag aaccgtgtgg ggtgaagtgg ctatgcctgg atatggcctg
    20521 tatgatcgtg caatgggact cacttacatg caaggtctat atgaggcgat aagtaaggaa
    20581 aaaccactgg gagagcatta tgaataaaat caagctcttc atctttgata tggatggcct
    20641 tttattagaa actggacgtt tagcttatcg tgcttatgta aaatcagcac aaaagtatga
    20701 ttatgaaatg cgtaaggaag tctattattt actaactggc caaacagaaa tggcgataag
    20761 agaacaaatg ggcattttgt acggagaaga tgttccatat atcaaatggc gagaagcaat
    20821 caatcaatat aaagaaaaaa tcgtgaaaga agataagaga gtatatacga aaaaaggagc
    20881 agaagaaatt ttatcttttg caaaagaaag aggaatccat acaatcgtgg cttcgtctaa
    20941 tacacgggta aaagtagaaa tgtatttaaa aatggaaaat ctatatgcct tgtttgatca
    21001 aatcatttca ggggatgatg taaaaaaagg aaagccggaa ccagagatct ttttgaaagc
    21061 ttgttcaaaa atgaatattc ctccaagtga agcacttgta tttgaagact cgattgcagg
    21121 gatcgaagca gcaaggcgag cgggcatttt gtcttttctc atcaaagatc atttgatagg
    21181 gttgcccgat cataatggga agcataagtt gaaagtagat gtaagtttat atgaatccaa
    21241 taaagcagac tatgaatttt atgacctgca tcaagcaaaa cgatttttag aaagtaaagg
    21301 gttgtatctc taataaagag gactattttc tagtcctctt tatttattgt cctgcacgac
    21361 tgagggaaca gatgaaaaag aagtaatttt ttattttgaa gtatctacct tatttgtagt
    21421 gaacaattta gaacaaacac aaaacgcatc tactgtt
//
LOCUS       DAFLWQ010000046        20717 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.047, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000046 DAFLWQ010000000
VERSION     DAFLWQ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20717
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.047"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            352..1041
                     /locus_tag="L1V16_001726"
     CDS             352..1041
                     /locus_tag="L1V16_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1276069.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1028..2236
                     /locus_tag="L1V16_001727"
     CDS             1028..2236
                     /locus_tag="L1V16_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1276070.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2530..3801
                     /gene="serS"
                     /locus_tag="L1V16_001728"
     CDS             2530..3801
                     /gene="serS"
                     /locus_tag="L1V16_001728"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBN1276071.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="L1V16_001729"
     CDS             complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="L1V16_001729"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBN1276072.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6339..7034)
                     /locus_tag="L1V16_001730"
     CDS             complement(6339..7034)
                     /locus_tag="L1V16_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HBN1276073.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7124..8224)
                     /gene="ychF"
                     /locus_tag="L1V16_001731"
     CDS             complement(7124..8224)
                     /gene="ychF"
                     /locus_tag="L1V16_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBN1276074.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8233..8424)
                     /locus_tag="L1V16_001732"
     CDS             complement(8233..8424)
                     /locus_tag="L1V16_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBN1276075.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8445..9335)
                     /locus_tag="L1V16_001733"
     CDS             complement(8445..9335)
                     /locus_tag="L1V16_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBN1276076.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9322..10089)
                     /locus_tag="L1V16_001734"
     CDS             complement(9322..10089)
                     /locus_tag="L1V16_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1276077.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10101..10814)
                     /gene="rsmG"
                     /locus_tag="L1V16_001735"
     CDS             complement(10101..10814)
                     /gene="rsmG"
                     /locus_tag="L1V16_001735"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBN1276078.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11046..12947)
                     /gene="mnmG"
                     /locus_tag="L1V16_001736"
     CDS             complement(11046..12947)
                     /gene="mnmG"
                     /locus_tag="L1V16_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBN1276079.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(12964..14361)
                     /gene="mnmE"
                     /locus_tag="L1V16_001737"
     CDS             complement(12964..14361)
                     /gene="mnmE"
                     /locus_tag="L1V16_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBN1276080.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14660..15043
                     /locus_tag="L1V16_001738"
     CDS             14660..15043
                     /locus_tag="L1V16_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276081.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15211..15969)
                     /locus_tag="L1V16_001739"
     CDS             complement(15211..15969)
                     /locus_tag="L1V16_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HBN1276082.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(15987..16805)
                     /locus_tag="L1V16_001740"
     CDS             complement(15987..16805)
                     /locus_tag="L1V16_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBN1276083.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(16802..17158)
                     /gene="rnpA"
                     /locus_tag="L1V16_001741"
     CDS             complement(16802..17158)
                     /gene="rnpA"
                     /locus_tag="L1V16_001741"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBN1276084.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17276..17410)
                     /gene="rpmH"
                     /locus_tag="L1V16_001742"
     CDS             complement(17276..17410)
                     /gene="rpmH"
                     /locus_tag="L1V16_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBN1276085.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            17934..19268
                     /gene="dnaA"
                     /locus_tag="L1V16_001743"
     CDS             17934..19268
                     /gene="dnaA"
                     /locus_tag="L1V16_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBN1276086.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDIKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19466..20596
                     /gene="dnaN"
                     /locus_tag="L1V16_001744"
     CDS             19466..20596
                     /gene="dnaN"
                     /locus_tag="L1V16_001744"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBN1276087.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
BASE COUNT         5928 a         4221 c         3802 g         6766 t
ORIGIN      
        1 tttccaacat gtcaacaact tattttttat tatttaataa gttattggtg ttcttttgaa
       61 caaataataa tatatcaaca tcacatgtga aagtcaataa gaaaatgctt atttatcaac
      121 atttctagct tacatgatca ttggttagtt ctggtccttt ttcgttcgtc tttataactc
      181 cgagagacgt aaaatccttt tgttttcagt ttaatgttca tgttcttgtc ttattcacac
      241 caactagatg tctcaccttc taaaattttc cttaacaaag tgctgctttt atctatttct
      301 gctttttttt gctagaataa tagtaacaat atgactctgg aggatttatt tatgaaaatt
      361 ttgattgctg acgatgataa agaaatcgtt gaattattaa gtatctatgt tcacaatgag
      421 gggtatgaag cagtaaaggc ttatgatggg aaagaagcat tatctaaaat cagaacaatc
      481 cctgatattg aattacttat tttagatatc atgatgcctg agatggatgg gatgcaagta
      541 gtgaaagagc tacgaaaaga atcccaaata ccaatcatta tgctgacagc aaaaactact
      601 gatatggata agatcaaagg actggtcgct ggtgcagatg attatgtgac caagccattt
      661 aatccgttag aagtaatggc tagagtaaag tctttattac ggcgtacaaa aatgcagatt
      721 gccccagatc agcctgatgt attagaagta aatgcattaa tcatcaataa agactctcat
      781 gaagttaaaa caatcgatgg gaaagaaatc cagttaacag ctttggaatt cggtatcctc
      841 tacttgcttg ctagtcatcc taatcgagta tttagcgcgg atgaaatttt tgagcgtgtt
      901 tggaaacaag aaagtattgt ctctgctaaa actgtcatgg ttcacgttag tcatttaaga
      961 gataagattg aagaagcaac tggtggtgaa aaagtcattc aaaccgtttg gggagtgggc
     1021 tataaaattg acgcaagata gtaaacgagc aactgaaaaa cgccgtcgga tcaatttgac
     1081 ttcaaaagaa atcagcgaat tgttagcgga aggaatcatc acgattatcc ttttgcttct
     1141 attaaatgtt tctattctgg ttgttatcag ttcggtgatc aacagttcac cttctttgac
     1201 gaatgcgatt tgggattcaa agaatatttt tgcagaacga ttgaacactg atttgttctg
     1261 gaacggccgg aattttatta ttcccttttt ctttctatta gatattggtg ttttgtattg
     1321 gcgcttgatt cgaagatatc gccaaatgca attgcggcat atcatcagcg aacttcacta
     1381 catcgcaaac ggaaattatg atcatcgtat cccttttgaa ctgagtggtg acttaagccg
     1441 agtggtaaca agtatcaatg gattggtgga tagtaccgta gcagcgattg aagacgaacg
     1501 taaaatcgaa aaatcaaaag atgaattgat cacgaatgtc agtcatgata tccgtacccc
     1561 actcacgtcc atcattggat acctaggact gatagaagat ggccagtatc actcagaaga
     1621 agatctttta aagtatacgc atactgctta tatcaaagca aagcagatga aatctttagt
     1681 ggacgactta tttgaataca ctaaggtacg ccagcctgct gtcccggtga atttttctgc
     1741 ctttgacatg atccagttga tcgaacagtt agcagctgat tttgagttgg aagcttctaa
     1801 aaaaaatatc caaatacttg ttcaatcaaa agtagactcc cttatcatgg atggcgatac
     1861 cgaaaaactt gtacgtgtct tcaataatct tttgacgaat gcgttgaaat acggaaaagg
     1921 agcaacgaag atcgtaatcg aagtagaacg tatcggttca gaagttgttg caacagtcaa
     1981 aaataacgga gcaatgatcc cacaacaggc aatcgataat ctattcgacc gtttttatcg
     2041 tgtagaagaa tctcgttcac aagcaactgg aggaactgga cttggtttag caatcgctca
     2101 aagcattgtg gctttgcacg gcggatacat ttatgcaaaa tcagataagc aatggacttc
     2161 tttcatcatg caccttccaa tcaagaaaaa tgaaaaatta cctattgata cacaggaagt
     2221 tattgacgaa agctgaaata ttcgctattc ttattacaat tattagaata aatgaaaaac
     2281 acagaaccca gtacacttta ttctttttca gagagctgat ggcaggtgta aatcagcaaa
     2341 ggataatttg gaagttccag ttcgtttacg tgccctttcg aaataagaaa ggtcggttca
     2401 acagccgtta tgtgttcaac aagtgcagct gacgctgaac ttgggtggta ccgcgaattt
     2461 cagactgatt cgtcccaaga ataatgggat ggatcagtct ttttttattt tcaaaaagga
     2521 ggaaatcata tgttagatgt aaaaatgatg cgacaaaata ttgaagaagt acaagaaaaa
     2581 ttgatgactc ggggcgtaaa aaaagaaaca ttagctgaat tcatggaact agatgaaaat
     2641 cgtcgtaagc tactagtcaa aagtgaagaa ttaaaaaaat atcgaaatga tgtttctgct
     2701 gagatcgccc aattgaagcg tgcaaaagaa gatgcttctg ctaaaatcgc tgaaatgaaa
     2761 gaagtcggtg gcaacatcaa agcattggat actgaaattg ctgaagtgga tgaaaaattg
     2821 aaacaaattg caactacttt gccaaacctt ccccatgatt ctgtgccagt tggaacagat
     2881 gaagaggaca atgtagaaat ccgtcgttgg agcgaaccac gtacatttgc ttttgaacca
     2941 aaaccacact gggaaattgc agaaaatctt gatattttag attttgaacg tggcgcaaaa
     3001 gtagccggta gccgttttgt ctattacaaa ggattaggtg ctcgattaga acgtgctgtc
     3061 tacaacttca tgcttgatca gcatatttac gaacacggct atactgaaat gatcactcct
     3121 tatatcgtca acagtaaagc gatgtttggt acgggacaat ttccaaaatt caaagaagat
     3181 gttttccaat tggagaatac tgatctaaca ttaatcccaa cagctgaagt accattaact
     3241 aactattata atgatgaaat tttagatggt gcagatttac ctatttattt cactgcacta
     3301 agccctgctt ttcgttctga agccggaagt gctggtcggg atacacgagg actgattcgt
     3361 cttcaccaat tcaataaagt agaaatggtc aaattttcgg atgtagagca ttcttacgaa
     3421 gaattggaaa aaatgacagc tgatgcagaa gatatcttga aaaaattgca tttgccttat
     3481 cgtgtgatgg ccttatcaac tggagacatg ggcttttctg cagctaaaac ttatgactta
     3541 gaagtatgga tacctgcaca agatacttat cgtgaaatca gttcttgttc taactgtgaa
     3601 gatttccaag cacgccgcgc aatgatccgt tatcgcgata atgatggaaa aatccactat
     3661 actcatactc tgaatggttc aggacttgca gttggccgta cagtagctgc cattttggaa
     3721 aactaccaaa atgaagatgg ttctgtcaca gttccagaag cgctcgttcc ttatatgggg
     3781 aatctgaaag ttattaaata aagaggctgt gaaaaagccg cttagtttcg agtattaaga
     3841 aaaattttgt gaaaatggct ttccacattt ttgcataaat tggacttaat accgagaaac
     3901 tggcttttga acaccattta tcgagaggtt gtgaaatcag cgaattaacc tgagtattag
     3961 agaaaaaaat ggaaaaatag tccctcatat tttaccgttt gttgaactaa taccgagggt
     4021 cagctgattg aacaccgttt agtggagagg tcgtaagcct accccccagc tcctagttac
     4081 aaggacaaat tcaaaaaaca gctcttcata ttttatgaat gttgtacttg tgattcggag
     4141 gtggcaaggg aacactgttt attcaaaaag aggctgggac agaagcgttt aactccaaga
     4201 aataagaaga aattcacgaa aattgctttt caaatttttg tgaatttctt cttatttccg
     4261 aaggagttgc ttctacttcc gccgtttata cgtgtttaga gcgtgagaca aaagtgttct
     4321 ttacttttgt cccacgctct ttaatgtttt taagattcaa ctgaatagtt tggtgcttct
     4381 tttgtgattt gtacatcatg agggtgtgat tcttttaatc cactgccgct catttggata
     4441 aattgcgctt catcacgtaa ttgctgtaga ttggctgccc caacataacc cattcctgaa
     4501 cgcaaaccgc cgatcatttg gaaaataata tctgcaacac ttcctttata agcaacccga
     4561 ccttcgattc cttctggtac taatttattt gcttcattga cactaccttg gaagtaacgg
     4621 tcttttgaac ctttttccat cgcgcctaat gagcccatac ctcggtatgt tttgaatcga
     4681 cgtccttgga agatttcgaa ttcacctggt gattcatctg tccctgccaa catacttcct
     4741 agcatcactg catgtccgcc ggcagctaat gctttgacga tgtcaccaga atatttgatc
     4801 cctccgtctg caataatcgc tttgccatat tgacgagcaa ctgatgctgc atcataaata
     4861 gctgtgagct gaggtacacc tacaccggct accacacgtg tcgtacaaat cgatcctggt
     4921 ccgataccaa cttttacgac atctacacct gcatcatata aagcttttgt cgcttcagcc
     4981 gtcgcaacgt ttcctgcaat caatgttgca tctgcaaaag ttgaacggat ttcttgaatt
     5041 tttcggatca cacctgcact atgtccatga gctgtatcga tgatgattgc atctgcccct
     5101 gcttctaata aagcattcgc acgctcaaat gtatcgcttg ttacaccaac ggctgctgct
     5161 acaagcaatc gaccatgttc atcttttgct gcatttggaa attcgatcac tttctcgatg
     5221 tctttgatcg tgatcaatcc gcttaaacga ccttcgttat ctacgattgg taatttttcg
     5281 attttatgtt tttgcaaaat cttttctgca tcttttagag aggtacctac tggggcagtc
     5341 actaagttgt cttttgtcat cacatcagca atcggcatgt gataatctgt tacaaaacgc
     5401 atgtcgcggt ttgtaattat ccctaccaat tttctgtttt caagtgtttc aacgattggc
     5461 acaccactga tacgatattt gctcatcaat tcttctgcgt ctgctacaag atgctgcggc
     5521 gttaagaaga acggatcaat gattacgcca ctttcagaac gtttgacttt tcttacttca
     5581 tccgcttgct ggctgatcgt catgttttta tggatcacac ctagtccgcc ttgtcttgcc
     5641 atagcaatgg ccatcttgct gtcggtaaca gtatccatac ttgcactgat gattggaata
     5701 ttcaacttaa tatttttagc taattgtacg ctcatatcca cttcgtttgg taacacgtga
     5761 ctttctgctg gtatcaataa gacatcatca aaagtaaatc cttttttcgt gaactttgtt
     5821 tcccagttgg acatttttag taccactcct ctaatttagt ttatctatta aaataattga
     5881 ttttttcatt taagtcaatg atctacttgg aatcaagtta gctttctcat agaataccaa
     5941 tataaagcgt ttacatctgt gtgtattaaa agagattgta aaaaagctgt cctgcatcaa
     6001 gtaataagaa cagccaatca aaaacagctt ctcatgtttt tgaattggtt gggtttatta
     6061 ccgcagatgc aaacttttga acaccgttta gtggagaggc tgtgaaaaag ctgcttagtt
     6121 tcgagtagta agaaaaattt tgtgaaaatg gctttccaca tttttgcata aattggactt
     6181 aataccgaga aactggcttt tgaacaccgt ttatcgtaaa aagggactgt gacaagactt
     6241 ttgtcacagt cccttactat tatttaacta tggataaaca aaatgaggtt ctttactacc
     6301 cctagatatc tagcaaaata gctgatcttt ttgctagttt atcttcttgg gacggataaa
     6361 cttccaataa tcccgtattt tttcttcaag tagtaacgga ttgctaaagc agttgccccg
     6421 ataatgataa ctactactgg atctaatact ggattgataa ctggtggcaa tagtgttgtc
     6481 gcagaaaaca gtacgaccca aagaagtgtc gttccaccta ggataagcaa tgtcttaccc
     6541 attcctggtt tcttgcttcg atctgctccg ggatattcat attgatagat gtatttgtac
     6601 atcatataaa agacccagcc accgattgca gaacctagaa cgagtgtaga aaagccataa
     6661 gctggcgttg ttccacgtga aaacaatccg gtaatcgcaa tcatgatact taatagacca
     6721 agcaacagca acgtattatc taaccacatc aataaagggg tggatgaatt ttttacttct
     6781 gctggcttat tgatgattgc ttccgttctt tcagagactg tcccaaacaa ttgacgggct
     6841 gttcttccgc ctttttgttc tgcaactaaa gtaggcagaa tgtcatgaag ggcttttact
     6901 ttttcttctt cagacaaatt cgctgcttct aaagattttt tcaaatcaaa aatgtactgt
     6961 tgatttcttt tggttaattt tgtttctaaa ctattgtttt cttttacgat tgctcgtaat
     7021 tgttctggtt ccattatcta atagtcctcc ttagccgttc cttttctcaa cggtcgtcac
     7081 aaaagacatt ctaccatatt ctacagctag tttgatagcc cttttacaca ttaaagcgga
     7141 ataacattac gtcgccgtct tgtacgacat aatcttttcc ttctaatcga acacgtccag
     7201 cttcttttgc tgcatgcatg tttccgtaat gatccaagtc ttcaaaagag acagtttctg
     7261 cacggataaa tccgcgttcg aaatctgaat ggatgattcc tgctgcttgt ggtgctttga
     7321 ttcctttttt gaatgtccaa gcacgtactt cttgttcccc agcagtaaag taagtagcta
     7381 agcctaacaa atcataagca gcacggatca actgatccaa acctgattct tcgattccta
     7441 aagcttctaa aaattccgct ttgtcttctt catctaattc tgcgatttct tcttctgcac
     7501 gagcactgac cacgatcact tctgcatttt cttctgcagc aaagttgcgc acttcttgta
     7561 cataatgatt cgcgtctgca tctgctacgt catcttctga gacattggct acataaagaa
     7621 ttggttttgt cgtcaataaa aatagtgatt taacgatttt ttgttcttct tcagtaaatt
     7681 cgatcgttcg ggcagatttt ccttcttcca gtacaggttt gattttatcc agtacagcta
     7741 gttctgccac tgcatcttta tctttggttt tagcaacttt tgctacacga gtatagcgtt
     7801 tgttgataga ttctaagtct gctaacacta gttccaagtt gatcgtatca atatcttcta
     7861 gtggatcaac acgtccttct acgtgagtaa tattatcatc atcaaaacag cgaacaacgt
     7921 gacaaatagc gtctacttgg cggatatggc ttaagaattg atttcccaaa ccttctcctt
     7981 tacttgcgcc ttttacgatt ccagcaatat ctgtaaattc aaaagtcgtc ggaacagttt
     8041 ttttcggatg tacaagttct gttaagcgtt gcaaacgcca gtcaggtact tctaccatcc
     8101 ctacgttggg gtcgatcgtc gcaaagggat agtttgctgc ttctgctcct gcttttgtga
     8161 tcgcattaaa caaagttgat tttcctacgt tgggcaaccc aacaattcca gcagtcaatg
     8221 ccataaattt attcactctt tctctgcatt tttttcaatt acttttttta atttcttttc
     8281 aaaatctcga cgggtcatca tgacgatatg tccgcaattc atacatctga ttttgatatc
     8341 tgcgcccatt cgaatgactt cccagcgatt cgtctggcaa gcgtgaggtt ttttcatttc
     8401 aacgatatcg tgcaagtcgt acataaaaat agcctccttt ttgtttattc ttcatcaaat
     8461 tgaatattca agatatcaag aattcgagtc aaatcttttt gagaaagata ttcaatctcg
     8521 atcttacctt tcccattttt ttcttggata gctacacttg taccaaattt atccatcaaa
     8581 cgatcttcgc tttctcggat ataatatggt ttttcctttg ctagccttgg gatttttttc
     8641 ttttcttttc catcattttg atttaactca gaaacaagct gttccagttg gcggacagtt
     8701 aaattttcag ttactgcacg attggctaat ttcaagatca atgttttatt ttttaaacct
     8761 aacagcgtac gggcttgtcc catagataaa cgctgatctt gtaccatttc cttgacaaga
     8821 tccggtaaag aaagcaagcg caaataattg gcgatataag gtctgctctt tcctaaacga
     8881 ctagctactt ctgcttgtgt tagtttcagg tttttcatca gcatctcata tgcttctgct
     8941 tcttctaacg gattcagatc ttctcgctgc aagttttcca gcactgctac ttgcatcatc
     9001 gcttcttcgt caaagtctct aacgatagca gggatcgttt ctttttcagc tagtttggac
     9061 gctcgaaaac gtcgctcccc tgcaataatc tcatatcctt ttactgcgga acggcgtacg
     9121 atgatgggtt gaaagacacc tgattgttca atagaattag ctagttcctg caaagatact
     9181 tcttcaaatg ttttacgggg ctgatacgga tttggtcgca gctcattcaa tggtagctgg
     9241 acaacggtat catcttttac atccaccgtc tctaagtttt ctaaatcttg aaacagtgca
     9301 tcgattcctc ggcctaatcc tttacttttc ttcacgactt accacttcct ttgccaatgc
     9361 ttggtagact tcagctcctc gagaacgtgg atcgtagtcg atgatcggtt ttccatgact
     9421 aggtgcttct gataaacgaa tatttcttgg aatgatcgtt tcgtaaactt tttcgcggaa
     9481 gtatttacgt acttcttcta cgacttcatt tcccagattt gttcgtgcat catacattgt
     9541 cagtaagact ccctcgatct ctaattctgg attaaagtgt ttttggacta aacgaaccgt
     9601 attcagtaat tggcttaatc cttccaatgc gtaatactca cactgaacag gtatcaaaat
     9661 cgaatcactt gctgtaaatg aattgattgt cagatggcca agagaaggcg ggcaatcgat
     9721 caaaatataa tcatactgac tgcttacttc tgctaaagat ccttttaatc ttgattctct
     9781 tgccatcatt gacgtcaatt cgatctctgc tcctgctaat tggagagtcg caggcacaat
     9841 actcaaattt tcgtgttcag tgatcaaagt tgcctcatca attggcaatt cattgactag
     9901 aacatcatag atgtctcttg tcacatcagg ttttctgatc ccgacaccac tggtagcatt
     9961 tccttgtgca tccatatcca ctagcaatac ttttttgcca aggctagcaa gacaagcacc
    10021 tagattcacc gtcgtcgttg ttttgccgac gccacctttt tggttcgcaa cagatattat
    10081 ttgtgccatc tcttctcctc ctatttgatt ggctgcttat taggcagtcc gggctttctt
    10141 gggtatttct ttggggttgg tttctttttt tgaataacga tgatatgccg ttgatcagag
    10201 acattcggca aggtaaccgc ctcttctttg aggaatttac cacctaataa agcaatcgct
    10261 tgttttgctt ctgtcaattc ctcttcactt tttgctgctt tcaatgcata aaaatagcct
    10321 tcttgtttag ccaagggcaa acacaattcc gctaacacat tcaaacgagc aaccgcacga
    10381 gcagtgacaa ggtcaaatga tgcacgaaag tgaggatttt gcccaaatgt ttctgcccgg
    10441 tcatgatata aggaagcatc gattcctaat aatcgggtta actcagataa gaaggttatt
    10501 cgtttattca gagaatcaac gatcgttatc tgcagttctg gaaaggcaat ttttaaaggt
    10561 atgctaggaa accctgcccc cgaaccaaca tcgcataaag ataaaggttg cgtaaagtct
    10621 acttcaaatg ctaatgtaag tgaatcgtaa aaatgcttca gatatacgtc tttttcatcc
    10681 gtaatagctg taaggttcat cttttcgttc cattcgacta atgtccgata ataaatagcg
    10741 aattgattca tttgatgatc ggtaagctct atcccttttt ctgccaagga ttggcgaaat
    10801 tcttctggta tcataaatat tcctttcatt gtgaaacagc aattgtttca cagattctct
    10861 ccctacttta acgcaaaatc tctagacatg caatccttcc atatggattc ttaaaaattt
    10921 gaaaagtaag aaaagccgat agactttttc tttctagtat gactcataaa atatacacag
    10981 aagagagaac tagctttgag caatttctgc aaaaactagt tctctcttct atttattatt
    11041 acgtattacg ctggttcact gactttcgca atcttccctt gttcgatata gaccattagg
    11101 atacttaggt ctgcagggtt tacgccactg attcggctag cttgggcaat tgtttctggt
    11161 tggattttct gcaatttttg ttttgcttct gttgctaatc cgttgattgc tgcgtagtcg
    11221 atgttttctg gaatcttttt cgcttccatg cgttttaatt tttctacttt ttccatggct
    11281 tttttgatgt agccttcata tttgatttgg atttctactt gttcgatttc ttttcgtgtc
    11341 aattcttcat tttctggaat aaaccgtaga agttctgcat aagtaatctc aggacgtctt
    11401 aaaaagtcgc ttgctagtac accatctttt aatggtgccg cattaatcgt tgctaaaaag
    11461 tcttggactt cttctgttgg tttgattcgt acattcatca aacgtttgat ttcttgttca
    11521 actgcttctt ttttcttcaa ataattcttg tattgatctt cttttactaa gcctacacgg
    11581 tgacccattt ctgttaatcg caaatctgca ttatcatgac gtaaaagcag acggtattca
    11641 gcacgtgaag tcagcaaacg ataaggttcg ttcgttcctt ttgttaccaa atcatcgatc
    11701 atgacaccga tgtaaccgtc acttcgtttg atcactaaag gttcttttcc ctgaactttc
    11761 aaagctgcat tgataccggc aatcagccct tgtccagccg cttcttcata accgcttgta
    11821 ccatttgttt gtccagctgt ataaagattt tcaacgactt tagtttctaa tgtcggacgg
    11881 agctggtgtg gctctactac gtcatattcg atagcatatc ctgtacgcat catttctact
    11941 ttttctaatc cagcaataga atgaagcatg ttgacttgaa catcctctgg taaagaagta
    12001 gataaacctt gaacatagac ttcttccgta tttaagcctt ctggttccaa aaataattga
    12061 tgacgtggtt tgtctgcaaa acgcacgatc ttatcttcga tggatggaca atagcgagcg
    12121 cctacccctt caacgatccc tgtaaacatt ggggcacgat gtaagttgtc tcgaataatt
    12181 tggtgagtcg tctcacctgt ataggtcagc cagcaagatt cctgatctag tttataggca
    12241 ctatctggtg tgctgaagct aaaatgattc ggctctttgt caccaggctg ctcttctgta
    12301 acagaatagt cgatcgtact tgattttact cgaggcggtg ttcctgtttt gaaccgttcg
    12361 atagcaaagc caagttcttt tagatgattc gctagtccaa tagaaggttg agagttattc
    12421 ggacctgatg aatatttcaa ttcaccgata atgatttctc cgcgaagtgc tgttccggct
    12481 gtaataacaa ctgctttggc ccggtagctc gctcctgtgg acgtcactac tccatgacaa
    12541 acaccatctt cgacgatcag ttcttcgacg attccttgtc ttagcgtcaa atttggttct
    12601 ttttcgatcg tatgtttcat ttctgttgaa taagcatgtt tgtctgcttg tgctcgcaat
    12661 gctcggacag ctgggccttt tcctgtgttc aacatacgca tttggatata ggttttatcg
    12721 atattcttac ccatttctcc gcctaacgca tcgatttctc gaacgacaac gcctttagct
    12781 ggtccgccta cagaaggatt acatggcatg aatgctacca tgtccaaatt tattgtcagt
    12841 aataatgttt ttgatcccat acgtgcagca gcaagtgcag cttctgaacc ggcgtgtcct
    12901 gcgccaacaa cgatcacgtc atacgcatct gcttcataat gttccaatcg tttgttcctc
    12961 cttttatttt cctaaacaaa attgactgaa taattgagtg attagctcat cttgtacact
    13021 gtcgccgaca acttctccta gatagtccca gcaacgcgtc atatctattt gaacgagatc
    13081 cacaggcatt cctgaatcaa tacctgcaat gacttcttca agtgagaggg aagctttttc
    13141 taacaacgcg atatggcggg tattagaaac ataagtagcg tctctttctc ctgtttctcc
    13201 gctgaagaat aaatcagaaa tagctgattc caaacgatct agtccgtcgt ttttagctac
    13261 ggaaattgaa aaaactggtt cattttcgat caatttcttc aatttttctt gttccagctg
    13321 tgctggcaaa tctgttttat ttagaagaat gatccgtttc aatccacttg tcgcttccaa
    13381 taattgttca tcttctgctg tcagtggttc gctttggttt agaacaagta agatcaagtc
    13441 tgcttctgct aatgcttttc ggcttctttc gaccccgatc cgttccacca catcttctgt
    13501 ttcccgaatt ccagctgtat cgattagctt gagcggtacc ccccgaacat tgacatactc
    13561 ttcgattaca tctcgagtcg ttcctgcaat atccgtaacg attgcttttt cttctcttaa
    13621 caaatggttt aacaaacttg atttgccgac atttggccgg ccgatgattg ccgtacttaa
    13681 cccttcccgc agaaccttcc cttgcttgga tgtagcaagt agcgcttgga ttctttgttg
    13741 gatcatctgc gctttttcaa gcaataactt cgtagtcaat tcttcgacat catcatattc
    13801 tggataatca atatttactt ctacttgtgc taatgtctct aaaatctctt gtctcaatga
    13861 gcggatcaaa gcagacagat tgccgtctaa ctgattaaga gctagtccca ttgctttgtc
    13921 tgtttttgcc cgaatcaaat ccatcacagc ttctgcctgt gaaaggtcaa cacgaccatt
    13981 caagaatgct cgttttgtga attcgcctgg ctcagctaat cttgcacctt ctcttaacaa
    14041 tagctgcaaa atttgattga ctacaacgat cccaccgtga caattgattt ctactacatc
    14101 ttcccgcgta aatgtctttg gtgctctcat cacggagacc atgacttcat cgacaagctg
    14161 attgctcttg ggatcaacga tatgtccata atggatcgta tgacttggta cttctgataa
    14221 tcgtttgttt ccagattgat aaactttatc tgctagttgc acagcttgat cgccacttaa
    14281 acgaacgata ctgattgcac cttctccagg tggggtagaa attgccgcaa tcgtatcaaa
    14341 ttctaaagta atttcagcca ttttttcact tcctttttca ttttgcgcac aaaaaaagtg
    14401 cccactccac cctttatgca caataaacgg tgaacttcgc actttgactg cttgttcttg
    14461 attaaattct ggtcatagat tatcacactt gctataagga atcaagtgtt taaaacaatt
    14521 agatgaagtt gagcctgttc tgcttccatt accttatatt taattgtcct tggatgtctc
    14581 tttgcgttct ttggtttatt cgaagagaag atactgtata aacaaggctt tatctttctt
    14641 aaaaaaaacg gtacactaaa tggtagcgct atctaaacta tacacttttg aaaggagaaa
    14701 atatgtgagc ccgttcagat ctgctgcatt ggaagaagaa agtgaccctc ggatcaacga
    14761 tgtcgtttta tctacaggga atatcaacca gaaatatatc gtccgcgata tcgtttttgt
    14821 tgtggaatgc ttagaagctg atttgtttga cccatctttt cccaaagatg accttttctt
    14881 aacaacgaag aggaaattaa agacgaaggt acttgaatat ggtgcgaatg cagtaatcaa
    14941 ctgtcatttt gagtatcagc aaaaaaaacg cgacggaaag tattttctgg aactttttgc
    15001 ttatggaaca gtgatccaat ttatccaaac aacgattggt taaatgaaac agacaaaaaa
    15061 agcggatcaa aactgaagac agtttcgatc cgcttttttc tatcaaagtt agtgactact
    15121 tcatcgtata ctctgataag aatgatttct agtaaaatat acttggtttg aaaaactttg
    15181 tcaacgtgat ttattcaaaa agtaatggaa tcaataatat tttttagcag gttctactac
    15241 taaataacga taaggttcct caccttccga atgtgttttt acatgttcat ctttgcttaa
    15301 tgcagcatgg atttgtttac gttcaaatgc aggcattggt tctaagaaaa caggctgccc
    15361 tgtccgtttt actttttcag ccgtgcgatc agctaaacgc tgaatgatct cttggcgctt
    15421 ttcacggtaa ttgcctacat tgactactac agacagctta tttcttgcta aacgatggat
    15481 gaagacttgt gccagatatt gcaatgcatt cagtgttttt ccatgtttcc caatcagtat
    15541 gccttgcttt tgtgtttcta aatggaaaac aaccatatta tttgattctc tttccatttt
    15601 gacaagagct ggagcatcaa gctgttttga aatttcagta agataaactg ccaattccgt
    15661 taaagctgct tcatcaccta gctcacttac ttcttctgtt ttttcttcaa gaatcgtttc
    15721 gttgactacc tcgatctcag ctgttggttc ttcttccaaa atttcttcta cagtctgttc
    15781 tactgtttca gaaacttttt cgctgatact tggctggatc gaaagccgtg cattctttcg
    15841 acccattcct aggaaacctt tttttccttc ttccagtatt tcgatttcga cttggtcttt
    15901 ggccaaaccc aaatcagcca gacctagttg gacagcttcg tctattgttg cagcttcata
    15961 aatcggcatt agcattacct cccctattat ttccgttttt tcttaggatt cattgctttc
    16021 ttaagagcac gttctctttc gcggattctc cgtgcttctt cttcacgctc ttttcgaatt
    16081 ttgaaagggt tgttgatcag cagcgtttgt acaacttgga aggcattgga aactacccag
    16141 tataatgaaa gaccgctggc taaattgaca cccatcacta aaatcattac aggcatcacg
    16201 aaattcatga tcttcattga tgcattcgat tcaatttgac tcatgctaga taaatacgta
    16261 cttgcaaaag taaagattgc tgctaaaatc ggcaaaataa atgttggatc cgcgttccct
    16321 aagttcaacc ataagaaatg cccttgtttc aactctggta cacgtgaaat agattgccat
    16381 aacgccatca agattggcat ttgtactaat aaaggaagac aaccagcata tggattgacg
    16441 ccattttctg catataaacg ctgctgctct tctcttaact tactttgtgt ttccggatct
    16501 cttgaactat attgttgctg cagtgctttt aatttcggtt gtaattcttg cgttttacgc
    16561 atgctctttg tttggaaatg catcaacggc aataggatca cgcggatgat cagtgtaaat
    16621 aaaatgatcc ctatccctgc attaccaaat gacaacgcct tgatcgcctc agcaaagtaa
    16681 taaacaatat aacgatccca aattcctgta ctctgtgcgc tgacttcccc agttccgcaa
    16741 ccggataaga cgatgaccaa actaacgata ccggccatca aaagtaaacg tttgtatttc
    16801 ttcacttact cttttcctct ctgtcgatta tttttgcaag ttttaagacg tggactaaat
    16861 tggagcgaac ctcatcataa gtcaacccct tcacacttgg tctagcaatc acaataaaat
    16921 ccaactccgg atcaatttct tcttttatag aataaactgc tgctcggatt tttcgtttga
    16981 cttcattgcg gtttaccgcg ttgccgacct tttttcctac agataaacca actcgaaaat
    17041 gaggctgtcc cggtttttcc aaacggtaaa cgacgaattt gcggttagca aaagaatctc
    17101 ccgtatggaa cacggcttga aactctcgtt ctttttttac tcgatacgct tttctcatta
    17161 gttttctttc cttttctatc tctcacttac gctcataatc ataccataat tacgattgtc
    17221 ctttcatcat ttccctaaaa aagagtataa aaaaaaccac tgaaacccca gtggcctaag
    17281 ctgaaagaac ttttcttcct ttgcgacgac ggctagctaa cacacgacgt ccatttttag
    17341 tactcatacg tttacggaat ccgtgaactt tttgacgttt acgtttattt ggttggtatg
    17401 ttcttttcat atattccacc tccaaaatgt tcttatctat tttataaaca cagacatact
    17461 ttgatagtat aacgacaaag tagtgatttt gtcaatataa aatagaagat cgattgttaa
    17521 aacttatcca caagattatt tttttctatg ggagtcctat gtggaaaaag ttatgcacag
    17581 ggattatcca cagataataa atggctggtt ttacacagaa aacacacgtg taaaaaaagt
    17641 aatccacaat caggtgattt cctgtgtatt ccgtctccta actattggta tatctatatt
    17701 ttttatccac agatgcaaga ggaaatctat tgatttttac gagttttcca cctgtgcatt
    17761 agtggtgtgg aaaacttttt tttgacaact gtgtttttct cttttttctt tttgtcgatt
    17821 gtgtggataa ttgtaattaa aaaatttttt tcttcggttt ctgtggaaaa ctattgaaaa
    17881 aaatgctaaa ttagtactag ttattcactt tttaatgaag gaggaggcct tatatggtat
    17941 ccctcgatgc tttatggaat gaattaaaag caacatacca aaaggattta tcgcctgcta
    18001 gctataatac atggatcgaa acagcgaacc ctcgaaccct tgatcaaaac cagctcgttg
    18061 ttgaggttcc tagcaagatt cataaagaat attgggaaaa aaacctggcg acaaaaatcg
    18121 ttgaagtcgg ttatatgtta tcaggaaatg agattatccc tcgctttatt actggcgaag
    18181 aagcagagca agaagaagtt atagaagaaa aaaatccaaa agttgtggca cctagtccgc
    18241 taaaaaaagc catgctgaac cctaaatata cctttgatac gtttgtcatt ggtaaaggaa
    18301 accagatggc tcatgcagca gcgctcgttg tagcagaaga tccaggttct atttataacc
    18361 cgctcttctt ttatggaggc gtgggacttg gtaagactca cttgatgcat gcaattggtc
    18421 atcaaatgct gcaaagtcag cctaatgcca aagtaaaata tgtaagcagt gaaacttttg
    18481 ctaatgattt catcaattcg atccaaaaca aaacagcaga agagttccgt caagaatatc
    18541 gaaatgttga tttactgcta gtggatgaca ttcaattttt tgcagaaaaa gaagctacgc
    18601 aagaagagtt tttccatact ttcaatgcct tgtacaatga agggaaacaa atcgtactaa
    18661 ccagtgatcg gttgccaaac gagattccga aactgcaaga acgcctcgtt tctcgctttg
    18721 catgggggct gtctgttgat attacaccgc cggatcttga aacaagaaca gcgattttac
    18781 gtaaaaaagc ggcggctgaa cgtctagaga tcccagatga cacactaagc tacatcgcag
    18841 gacaaattga ttctaacatt cgtgaattag aaggtgcgct tgttcgagtg caagcttttg
    18901 ctgcgatgaa tagtgaagat atttcgacta gtctagctgc agacgcactg aaaacgttaa
    18961 aatcaggaaa aggacatcct caattgtcaa tcctgcagat ccaagaagaa gtggcaaagt
    19021 attatcacat ccaattgaaa gatatcaaag gaaagaaacg cgtcaaatct attgttgttc
    19081 ctagacaaat cgctatgtat ttggcacgtg agctcacaga taattcttta ccgaaaatcg
    19141 gagctgaatt cggtggcaag gatcatacaa cggttatcca tgctcatgaa aaaatccagc
    19201 agctgatgga ttctagtgtc agtatgcaaa atgaagtatc agaaatcaaa aactttttac
    19261 taaattaatt tgtcgattct atcaactgaa aatagcatgt ggataaaaga aaaaaacgtt
    19321 caaaagttat gcacactttt tccacagctg ttttttcgtt tctctcttac gttttttgag
    19381 ttttccacag aatcaacatg ccctattact tttattattc tttttaacta ataataaata
    19441 aacaaacatt caaaggagat acatcatgaa agttacttta aaccgagcta gctttatgca
    19501 ggaattgcaa actgttcaac gagctatttc aagcaaaacc acgatcccta ttttgacagg
    19561 tgtaaaaatc acactgacac aagaaggttt gactttgacg gggagcaacg ctgatatatc
    19621 aattgaaact tttttgtctg ttgaaaacga aaaagcaaat atgcaaatcg aatctactgg
    19681 ttccattgtt ttacaagcac gtttctttag cgaaatcatt cggagacttc ctgaagaaac
    19741 atttacttta gaagttttag aaaataaaca agtagcgatt acttctggaa aagcgaattt
    19801 tatcgtaaat ggattagatg cagataacta tcctcatctt cctgttgtcg aaagccataa
    19861 ccagatgaaa ttacctgtac acgtattgac taaactaatc aacgaaacag tttttgctgt
    19921 ctcacaacat gagagtcgtc caatcttgac aggtgtgcat ttcattttat ctgataattc
    19981 tttattggct gtagctactg attctcaccg tctaagtcaa cgcgtgattc cagtagaaca
    20041 agcggctgat cattttgata ttgttattcc tggaaaaagt ttgatcgaat tatctcgctc
    20101 attaacaaat gaagaagaaa tcgtcgaaat cagcattatg gaaaaccaag tgttgttcaa
    20161 aacagaaacg atgtatttct attcccgttt gctagaagga aactatcctg ataccaatcg
    20221 tttgattcct tcaagtttta atacagaggt tgaattttct gttcctagct ttttagcggc
    20281 gatcgaacgg gcttctttac tttctcatga aggccgtaac aacatcgttc gtttatctat
    20341 tcgtccagat gcggttgttt tatacggaaa ttcgccagaa atcgggaaag tagaagaaag
    20401 cttgagttat acagcaagca gtggcgatcc attagatatt tctttcaatc cggattatat
    20461 gaaagcagcg ttgcgtgcat ttggagatat gagcatcaaa gtgaaattta tctctgctat
    20521 tcgtccattt acattggaac caacggaaga tggcgttcaa tttattcagc tgattactcc
    20581 tgtacgtaca aattaacaat gattttcatt gttcttgaaa atttaattga aaagaaatag
    20641 aaaaaataaa attttaaaca gaaggcccta aaatctcttt taaggctttc tgtttatttt
    20701 tgtttaaatc acctttt
//
LOCUS       DAFLWQ010000047        19562 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.048, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000047 DAFLWQ010000000
VERSION     DAFLWQ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19562
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.048"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            56..715
                     /locus_tag="L1V16_001745"
     CDS             56..715
                     /locus_tag="L1V16_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBN1276088.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            800..1705
                     /locus_tag="L1V16_001746"
     CDS             800..1705
                     /locus_tag="L1V16_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBN1276089.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(1707..2339)
                     /locus_tag="L1V16_001747"
     CDS             complement(1707..2339)
                     /locus_tag="L1V16_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBN1276090.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    2490..2615
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            2659..3183
                     /gene="infC"
                     /locus_tag="L1V16_001748"
     CDS             2659..3183
                     /gene="infC"
                     /locus_tag="L1V16_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBN1276091.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            3255..3455
                     /gene="rpmI"
                     /locus_tag="L1V16_001749"
     CDS             3255..3455
                     /gene="rpmI"
                     /locus_tag="L1V16_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBN1276092.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            3508..3867
                     /gene="rplT"
                     /locus_tag="L1V16_001750"
     CDS             3508..3867
                     /gene="rplT"
                     /locus_tag="L1V16_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBN1276093.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            4119..5456
                     /locus_tag="L1V16_001751"
     CDS             4119..5456
                     /locus_tag="L1V16_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBN1276094.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            5504..7633
                     /locus_tag="L1V16_001752"
     CDS             5504..7633
                     /locus_tag="L1V16_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBN1276095.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            7608..8297
                     /locus_tag="L1V16_001753"
     CDS             7608..8297
                     /locus_tag="L1V16_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276096.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(8705..9318)
                     /locus_tag="L1V16_001754"
                     /pseudo
     CDS             complement(8705..9318)
                     /locus_tag="L1V16_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(9454..9648)
                     /locus_tag="L1V16_001755"
     CDS             complement(9454..9648)
                     /locus_tag="L1V16_001755"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276097.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(9698..10138)
                     /locus_tag="L1V16_001756"
     CDS             complement(9698..10138)
                     /locus_tag="L1V16_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HBN1276098.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(10142..10987)
                     /locus_tag="L1V16_001757"
     CDS             complement(10142..10987)
                     /locus_tag="L1V16_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HBN1276099.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            11136..12554
                     /gene="pepV"
                     /locus_tag="L1V16_001758"
     CDS             11136..12554
                     /gene="pepV"
                     /locus_tag="L1V16_001758"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBN1276100.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(12611..13558)
                     /locus_tag="L1V16_001759"
     CDS             complement(12611..13558)
                     /locus_tag="L1V16_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1276101.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(13781..14131)
                     /locus_tag="L1V16_001760"
     CDS             complement(13781..14131)
                     /locus_tag="L1V16_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBN1276102.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            14331..15410
                     /gene="pepA"
                     /locus_tag="L1V16_001761"
     CDS             14331..15410
                     /gene="pepA"
                     /locus_tag="L1V16_001761"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HBN1276103.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            15554..15874
                     /locus_tag="L1V16_001762"
     CDS             15554..15874
                     /locus_tag="L1V16_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBN1276104.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            15896..16360
                     /locus_tag="L1V16_001763"
     CDS             15896..16360
                     /locus_tag="L1V16_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBN1276105.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            16565..17170
                     /locus_tag="L1V16_001764"
     CDS             16565..17170
                     /locus_tag="L1V16_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HBN1276106.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(17209..18498)
                     /locus_tag="L1V16_001765"
     CDS             complement(17209..18498)
                     /locus_tag="L1V16_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBN1276107.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            18926..19405
                     /gene="rlmH"
                     /locus_tag="L1V16_001766"
     CDS             18926..19405
                     /gene="rlmH"
                     /locus_tag="L1V16_001766"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBN1276108.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
BASE COUNT         6230 a         3598 c         4014 g         5720 t
ORIGIN      
        1 tttaaaaagg ttggagttaa acacaatatt tagtgatgaa gtgagctgga ggtaaatgag
       61 cgtgatcgtt ttagcaggta caattggtgc cggaaaatca agtttaacag aaatgatggc
      121 tgaacacttt gatagtcagg cattttatga atcgattgat gataatgaag tcttgccctt
      181 attttatgca aaccctgaac agtatgcttt tttgctgcaa atttattttt tgaataaacg
      241 ttttgcaagc atcaaacaag caatgaaaga tgacaataat gtattggacc gttcgattta
      301 tgaagattca ctgcttttcc atctaaatgc agatctagga agagcaacag aaacagaagt
      361 tcgtgtgtat gatgaactgc tggaaaacat gatggaagaa cttccctatg ctgcccataa
      421 aaaacatccg gatttattag ttcatattcg tgtatctttt gatacgatgt tggagcgtat
      481 cgaaaaacgt ggtcgttcgt atgaacaatt gtcctttgat ccaagtctat acgattatta
      541 caaagaattg aacagacgtt acgatcaatg gtatgaagaa tacaaagaaa gtccaaaaat
      601 ccaaatcgat ggagaccgct ataattttgt ggaagatcct caagcaaaag aagaagtctt
      661 gaaaatgatc gaagaaaaat tagcagagat tcgccaaacc aaagtagcca tttgatttac
      721 agttgctcaa ataaagggta aacctttatt tgagcgactt ttttctttat actggaaaca
      781 aatgtcagga ggatagagta tgcgggaaaa acactatttt aatcaagacc gtaatttttg
      841 gatcaatgta cagcaaaacg atgtgctagc tgttaaaaac ttaaaagaag aatatggcat
      901 tagtgacgag atgctgactt attctctaga taaaaatgaa cgggcgcgcg tagagtacga
      961 ttcttttgat gaagcgttac tgcttgtatc aaatgttccg caccagcaaa aagtcgataa
     1021 tcattatgaa actagtccta tcgcttttat tttaaaagaa gacggtttgt ttacatttac
     1081 cacgccgaat accgagtacg tgattcgact aattcgatcg cttttggaac gaatgccaga
     1141 catgagtgta tacagtttat tgtttcgtac attgtttttg atttctgatt ccttttttcc
     1201 tttaatcgag gaagtgaata gtgaacgtca gcggcttaat ctgaaattaa gagaaaaaac
     1261 aacgaacaag aatctgctgc aactttcaga tttagagatc ggtttggttt acttagttac
     1321 aggaacaaaa caaaatgtag tacttttaga acaaatcaag gcattggcta tttatcgcaa
     1381 gttgtcagaa aaggaaaaag aagagttgga cgatgcgctg atcgaagcac gacaagcagt
     1441 tgaaatgacg aacttagctt cgcagatttt agaccagctc tctggcactt ataataattt
     1501 gctgaataac aacttgaatg acacgatgaa atttttgacg gtctggtcgc tgatcttgac
     1561 cgttccaact attgtgacag gattcttcgg aatgaatctc cagttaccct ttacccattc
     1621 cgttttcgga tggggaatcg ccttgatcat cagtttggtc ttatctattt ggatgcttat
     1681 tgcactgtgg cggcggattc gttgatctag tctttgatct gcaaaccaag ggcttgggcg
     1741 atcacaagtg cttgctcttg gttgacgatt agtcccgcca aagaatcttg agataaagcg
     1801 attgctgtga agaaattagt cgtaaagtct aatcccttca gagaagttcg aaaccagttc
     1861 gaaccggtca actgattgtc agacaaaaaa aggtttttcc aagtgacctc ataaaattcg
     1921 ctgtcttcta attgacaatg atcgaaggag acagctttca agtttgtact actaaaggaa
     1981 gccatcgaag caatacaatc agtgaaagta cagtctcgaa gataactttc ggcaaaattc
     2041 gtacctgtta atttacattg atgaaacacg acttggtgga aactgccacc aatccactcc
     2101 agattggaaa aatcacattt ttcaaaaatg acattactgc attcaaaatg acgtaaaact
     2161 gttttttgca tcgtaagttt ttggatatga ctctctctta ataccatatt tttggcatcg
     2221 agatagcttt ggtcaccccc gttgatcaga agaccagaga agatctcctc atcttctaaa
     2281 taaaactctc cctttgtaag aagaggaaga gaaggtggaa taggttcgat ttttttcatg
     2341 tgggttcacc tcgtttttct ttagtatagc aaagaagcgg gaatcactgc tagaaagtct
     2401 gctaatctaa tcattttcag aaaaggaaga caaactgtat gaaaaacatt gacaaaaaga
     2461 ttagtttttg ctatactatg atggttgaga aataaaagca gaagcacccg cttctcgcct
     2521 tagttgataa tgtcactggg ctagatagtt ttcactggtt ctattaggtg aagtacgcgc
     2581 gggttctgta agagaactcg tttttttatt gccgtttatt cggtaagctt ttctttctct
     2641 cataatattt ggaggtgaat gaccatagca aaggatatga tggttaacga cggcattcgt
     2701 gcacgagagt tacgattgat cggttcagat ggtgagcaat taggagttaa gacaaaagca
     2761 gaagcattga atattgcaga acaagcaaac ttggatcttg tgttagttgc ccctggtgcg
     2821 aaaccaccag ttgcgcgaat catggactac ggtaaatacc gtttcgaaca acaaaagaaa
     2881 gaccgcgaag cgcgtaaaaa acaaaaagtg atcaatgtaa aagaagttcg cttaagtcct
     2941 acgatcgact tgaatgactt caatacaaaa cttcgtaatg cacgtaagtt cttggaaaag
     3001 ggcgataaag tgaaagcttc tatccgtttc aaaggccgtg ccattaccca taaagaaatt
     3061 ggtcaaaaag tcttgaatcg cttagctgaa gaaactgcgg atattgcaac agtggaacaa
     3121 aaagcgaaaa tggacggacg cagcatgttc ttgacgctgg caccgaaaaa cgacagtaag
     3181 taatttgaat gactaactgg ctgttggaca gccgatagtc ggataacgaa agattttgag
     3241 gaggaaatat agtcatgcca aaacaaaaaa cacaccgcgg atcagcaaaa cgtttcaaac
     3301 gtactggtaa aggcggattg aaacgcttcc gcgcgtttac aagtcaccgt ttccacggca
     3361 aaacaaaaaa acaacgccgt caattgcgta aagcaagcat ggtttctagt ggcgacttca
     3421 aacgtattcg ccaacaacta gcaaaaatga aataagaagt acaaataaca gaatctgaag
     3481 atttattttt attaggagga attatacatg gcacgtgtta aaggtggaac agtaactcgt
     3541 aaacgtcgta aaagagtgct aaaattagca aaaggttact acggttcaaa acacacttta
     3601 tttaaaacag caaaagaaca agtaatgaat tcatacaact acgcatatcg cgatcgtcgt
     3661 caaaagaaac gcgacttccg taaattgtgg attgctcgta tcaacgcagc agctcgtatg
     3721 aatggcttga gctactcaaa attaatgcac ggtttgaaag ttgctgaaat cgacatcaac
     3781 cgtaaaatgt tagctgactt ggctgttaac gatgcagcag catttactgc attggctgac
     3841 caagcaaaag aagctttggc taaataagct aaacaattat aaagaggaaa gaagataacg
     3901 aaaagttatg ttctttcctc tttttttatt tacaatcctc catcaaatga aacaggacaa
     3961 taacgtataa gtctaaaata gcataattaa ggttttttaa ttgaaaactg aacatttatg
     4021 gtcacccttt aatgaaagcg ctaactacat aagttagaat gagtttgact gatatattag
     4081 tttgcttatc agaaaaacaa aatggacgga ggaataacat gagtgatatt attattggta
     4141 ttttgttagt tatctcattc tttttcatgg tctggtactg tgtaaaaggc tacaacttga
     4201 tggtcggctt tgccatcatg gctactgtat ggatgggatt agcgctagtc ggaaacacgt
     4261 tttcaccaaa cccggcgatg gaagggcaag gagtaattga tgtgttgacg catatctata
     4321 cgacggggcc agctgagtac gccaaatcga tcttggtaaa tgtcttcttt ggtgcctttt
     4381 tcgggcgtgt tctagtagat agcggaatcg cagctaccct gattcgaaag gtagttgaac
     4441 ttggagggga caagccaaga atcacgatga gcttactatg tattgtaacc gctgttatat
     4501 tcatgtcgat gacaggaatc ggaccagtga tttctattgc agttattgtg ttgccaatct
     4561 tgatgtcatt aggtatttca gtaccggttg cactgttctc atttatgggc tcgattatgg
     4621 ctggaatctt tgctaatatc gtcaatttca aacaatatca aacgatttat gctggtttca
     4681 atccagcggc tgaaagctat acttataatg actatttcca aattggtatg attgggatga
     4741 ttgtaagctt agttgtggta ctaacggtcg ctaatatatc aatgaacaaa aagaaacgct
     4801 atgcaatggc agcaaacgta ccagctgaag gtggcgacgc accaatgatc tcatggttag
     4861 ccgtattatt accagtttta ggggtcgttc ttttagatct tccaatcatc ttaggtttta
     4921 ttctagcagg tatctgggca ttgctgttta ctggaaaatt gcgcggaggt tataaagaaa
     4981 tctgtcgtca gtttgcgaaa ttatttacag atggcgcagt agatgttgca ccaatggttg
     5041 gtttcttgat gaccttagcg atgttcaata attcagctgc gtatgcttct ccttattttt
     5101 cagctatttt tggagattgg ataccgcaat caccattagt cttggcaatc gtatttgcta
     5161 tattgacacc actaggattt ttccgcggtc caatgaatct agtcggttca ggctcagcta
     5221 ttttagctgt cgtattagct gttaatccaa cgatgtcgcc agcctttttg ttcccgttat
     5281 ttgcaatcac aacgattgct cctcagcatt tagatattac acaatcttgg gttgcttggg
     5341 gattaggtta tacaaaagta acttctcgag aatatatgaa gaaatccatc ccaactggtt
     5401 ggatcatcgg agcgatctta tgcctgatca cgttcttatt gtacgggaac gcctagtaaa
     5461 caaaacgtcg ataaaaacga ttagatgaat ggaggaaaag aaaatgaaac gttttgtgcg
     5521 aatgggaatt gatgttggcg gtacacatac gaaagcagtc gcaatcgata atgcgacgca
     5581 cgaaatcatc ggaaaatctt cagtgaaaac aacccacgat gatgtccgtg gagtagccgc
     5641 aggtgtcgtt cagtcttttc aaaattgttt gcgggaaaat aatatcagtc cagaagatgt
     5701 tgtgtttgtt gcacattcta ccacacaagc gactaatgca ctgattgaag gagacgtagc
     5761 aaaagtcggc gtaatcggga tggcaaaagg tggattagaa ggttttttag caaaacgaca
     5821 aactagattg aacgatatcg atttagggaa taagaaaaaa atagagattg tcaatgcatt
     5881 cttacctgtc aaacacttaa atgtagaccg tgtttcagaa acgatttctt ctttagaaag
     5941 agaaagagcg gaggtcttgg tttcttctat ggcatttgga gtagataatg gggaaccaga
     6001 acgagttgtt tatgaagcag catcggtaaa atcgatccct acaacgatgg cttctgacat
     6061 cacaaaatta tatggattga caagaagaac tcggacagca gcaatcaatg catctatttt
     6121 accaaaaatg ctagatacgg caacctctac agaagattcc gtacgagaag caggggtcaa
     6181 tgtttctttg atgattatgc gcggagacgg cggagtaatg gaaatcaatg aaatgaaaaa
     6241 acgacctgtt ttaaccatgc tttccggtcc agcagcatca gtcatgggct ctttgatgta
     6301 cttgagagcg tctaatggtg tttattttga agtaggcgga acaacaacca atatcggggt
     6361 cattaaaaat ggacgtccag caatcgatta ttcaattgta ggtggccacc caacatatat
     6421 ctcttcatta gatgttcggg ttctaggtgt ggcaggcggt tcgatggtac gggctaatca
     6481 gtcaggaatc atcgatgtcg gtccacgttc tgcacatatt gccggtctag attatgcagt
     6541 atttacggag acagaaaaaa tcaaaggtcc taaggttgaa tttttctctc ctaaagaagg
     6601 agaccctgct gattacgtca aggtagtgat ggaagacgga gaagaagtga ctattacaaa
     6661 tacatgtgca gccaatgtcc ttggattagt gcaagaagaa catttttctt atggaaatgt
     6721 cccatctgca cgaaaagcca tccaagcatt agctgattat tgtcatacga cggttgaaga
     6781 catcgcagaa cagatcatgg aaaaatccta tgctaagatt gaaccggtga ttttagaatt
     6841 ggcagacaag tatcacttgg agaaagatca gatttctctt gtaggtgtag ggggcggcgc
     6901 tgcctcattg attacttact ttagtaataa aatgggtgtg aaatattcga ttcctgaaaa
     6961 cgccgaagtg atttcttcta ttggtgtagc acttgcaatg gtccgagatg ttgtagaacg
     7021 tatcatccct tcgccaagta aagaagatat acgatcgttg aaaaatgaag cgatgaataa
     7081 agcgattgaa tcaggcgcta caccagaatc gatcgaagtc cacgtagaaa tcgatccaca
     7141 gacttcaaaa gtaacggcta tcgctactgg ttctacggaa gtgaaagcaa ccgatctaac
     7201 caaggagatc acaacagaag aagcactaga gcttgctgca gaggatatgc gattaaataa
     7261 aaatgaagtt tgcttattgg aaaatacacc tttcttttat gtatgcggcg aacagaatcg
     7321 ttcaaaaaat gctggaagtc ttcggatcat cgatcaaaaa ggatttatca aggtccaacg
     7381 tggacatgct tcatgtatga aaacaactgc agccaattat atgacagctg tcgaacaact
     7441 ttgggaagat atggcagttt atcaaactga attgattgcc cgaccagaat tttatctctg
     7501 cttaggagca agagtctctg attttacagc gacggatctg gaacaactac agcttttgat
     7561 ggatctggaa gtatctacta tggaaccgga ggaagaagtg atcgtcgttg ccggaaatat
     7621 caaacaaaca taagttagaa gagttactaa acgaattaca acagatcccc gaagaaattt
     7681 ggggattcta ccagtttcgg cgagatttat tttggaaaaa gattcctttg tccaagcaga
     7741 aaattcttat acaacaatca atcgattgtg gtatcgaaac ggcatgtagc atcaaaaaaa
     7801 agtacccttt tgccgatgta ggagaaattt gtgaacaaat ggctgttcca atcgtttcct
     7861 gtgaatcaga gcaaataaac gaacgaatca cttttgcaac ttatgcagaa gatgaaggga
     7921 ttcgattgat gacggagccg ttagaaaaat taaaatgttc aggactagct tcgatctcta
     7981 aagaaacagc gcaagctttg attattggac atgaactatt tcaccacatc gaagcttctg
     8041 ttaagggaat ttatacgcaa agcgaaaaaa ttgtgctgtg gcggttgcct ttttatacac
     8101 atcaatcaaa cattcgtgca ttgagcgaga tagcagcgat gagtttttca aaagagatga
     8161 atcaaagcga tttttcgcct tatgtattag aggcagtctt actttggcca tataatgaaa
     8221 ttcgtagcca agggatctta gaagaaataa aaaaaataga aaaaagatgt acggagtatg
     8281 atttagatta caaataaaga gactgtgaca aaagtcgtgt cacagtcctt tttttccgaa
     8341 taaacgatgt tctcctgtca actcctcggt cacaagtcaa aatattcaac aaacatgaga
     8401 agctgttttt tgaaattgtt ccttgtgact cggagatgaa cggcaggctc acgacctctt
     8461 ggaaaacggt gttcaaaagc ttgcatctgc ggtaataagt ccagccaagt taaaaacata
     8521 agaagctatt tttacttggc tgttcttatt acttgatgca gggcagcttt ttcacaacct
     8581 ctcaataaac ggtgtgcaat cagctgaccc tcggtattag ctcaaaaaaa acggcaaaat
     8641 atgaggaact attttgccgt ttctttctct aatactcagg tcaaaacgct gattccaaaa
     8701 cctcttattt gatgggtctg tcctgaatat cttcaaaata atcggggtaa ttatgaatca
     8761 cgtattcttg ctcctcgata atcatatgta aatgcatcgt gcaaagaaat ccgacttcat
     8821 caaagttatg atcaatcatt gattgaagca ttgtctgatg ttcatctaat actcgacccc
     8881 agtctaattc tgaaatcgtc aaacgtaacc atctgaaacg gttcaagtgc gtactataac
     8941 tttctagcca atcccaaatt tctcgttttc cagcaatttc ataacaagtt cggtgaaaat
     9001 cagtatccaa atcaaaaaaa gcttttttat tttgagcgat tactgcctga tcggtttttc
     9061 caacttttcc cgcgtataac gggctaatga agcagatcgg atatcgattt ttgaaacata
     9121 agtgccggac tgtggaatgg tttttacaag ctcttgattg cgcagttgga tcagtgcttc
     9181 tcgaatcggt gtacgcccga tagctagttg ttcttctaac actttatcgg agattttact
     9241 tccaggtgct aactcggaat aaatgatttg tttacgtata gattcataag cttgctgttg
     9301 caaattattg ataaccattt aaccttcctt tctatgcaga tataatctat tataacataa
     9361 atcgcttaca aatcgtgtgg gcataaaaac acagtctgca aaaaaagccc tgataggcat
     9421 gcctattaga gcctcgaaaa gaaaaatatt gaatcaatct ggtcgtacct cttgtatcgg
     9481 tttgacacga ccgccgattc ttttagcaaa agcttcggat tcttttttgt ctttgaaaat
     9541 gagcagattg tctaagtttt tttcccgagt gcgacagcca gttttatcga tgtaaccgtg
     9601 cattacttta acgacataca tggggatcac ctgctttttt cttttcatta tacgaactac
     9661 tcgacacaat acaagaaaaa tgcttagacg gtctttatta agaatttaca tcatccaaag
     9721 aagcgtacgc ttggaataac tgatctaact ccggattgac tttgctcagc ttcactaatc
     9781 gttgcgaatc agaaagtaaa aaacagtgtt tactactgcc agtagttttt aattttttgt
     9841 cttcagttcc cacaatttcg tagctaaaat ccaaccgtgt ccccgtatac ttttggatag
     9901 ttggatggat gctcactttt tctccgtaat ggatcatttc tttatagctg caatttactt
     9961 ccagaacggg gatgatgatc ccagattctt cgattttttt atagggaaac cctagatgta
    10021 ccaataaggc tacccgagcc tcttcaaacc agcggatata attgctgtga tgaataatcc
    10081 ccatttgatc tgtttcataa taaaaaggtt ctcgcacata acctgtaaat ttctccatga
    10141 ctcatgcctc gttttccatt gattttttac aaaaataatt catccatttc ggaagtgctt
    10201 cgctgatttg tgtcggcaaa acaatatatt gttcttttgc cagctggtct ccaatgaaac
    10261 tatgaagata aatagctgct gcaatcgttt ggtcattttg aggaaactgg gctaaaaatc
    10321 ctgtgatcat cccagctaaa gtgtcaccca tgccgcccgt tgccatagca gcagaaccta
    10381 aaggattggt gtagaagtgc tggtgaccat aaatttttgt ctcatgactt ttcaaaacga
    10441 gcacagcacc gatttcctgt tgcttctttt tgttttcttt atcccgttgt tcttgtatcg
    10501 gtagagaact caaccgttgc cactccattt gatgaggtgt aagtacagtt tgttcgggat
    10561 agggtagcaa aagatgatta gcagcaagta aacttaaagc agagccatca atcaccagcc
    10621 attgttcttt tgattggttt tctagtactt gtttgaaacg ttccaaactc ttagaagaag
    10681 tacccaatcc gggaccaatc aagagtacat ctgcttgctt tattacggaa agaaactggt
    10741 cagtatccgt ccaaactaca atcattgctt ctggcagatg actgtgaaga gcactccgat
    10801 ttttttcatc agttactaca gtcgtgagac ccgctccgct gtgtacggca gctaaagcac
    10861 tcataatgat tgctccgcca tattgttcat tgccgccaat caaaacgata cgtccaaatg
    10921 ttcctttatg tgaaattttt ggacgaggtg tgatgactct tttcactagt tgttcgttta
    10981 tcagcatcta aaaacctcct tttactcatt atagcgtata ttttttttag agaaaaacag
    11041 ataagaaaag gaattgtcag attttttgaa ctattttttt ctgtaatttg tggtatcatg
    11101 aacacgaaga cttaaataag tggaggatta actttatgac aattgattgg caaaaagaag
    11161 tagaagcacg taaagaagac ttgcttgaag acttgaaaaa tcttttacgt gtcaacagcg
    11221 agcgcgatga ctcaaaagta acaccagatg caccatttgg acctggacct cgcgacgcat
    11281 tgaaacatat gttagcttat ggcgaacgtg atggatttaa agtaaaaaat gtcgataact
    11341 atgcagggca tattgatctt ggcgaaggag acgaaacgct agggatattt ggacacatgg
    11401 atgtcgttcc tgcaggagat ggctgggaca cagatcctta tgaaccagta atcaaggatg
    11461 gaaagatctt tgcacgcgga tcaagcgatg acaaaggtcc aagtatggca gcttactatg
    11521 cgatgaagat cattaaagaa cttgacttga aactatcaaa aaaagttcgc ttcgtagtcg
    11581 gcagcgatga agaaagcggc tggggcgata tggcttatta tttcgaacat gaagaagaac
    11641 cagattttgg tttctcacca gatgctgaat tcccaatcat caatggtgaa aaaggaaatg
    11701 tttctttagc tttacgcttc aaaggcgaca atgcaggaga ttatgtcttg aaatcttttg
    11761 tttccggact tcgcgaaaat atggtgccag gaacagcaac tgcagcactt caagtaccaa
    11821 gtgcagatgc agctatcgcg atggaagaag cattttacca attcatcgaa gcaaatccag
    11881 taagcggaac gattgaagcg gacaatacgt atgtaaaaat cgaattagtt ggtaaaggcg
    11941 cacatggtgc aagcccacaa tctggtatca atgcaggttc tttcttggca ttgttcttag
    12001 ataactatga attcctagga tctgctaaac aatttatcca tgtagcagct gcttatgtcc
    12061 atgaagattt ttatggagaa aaactaggag tcgcttatga agatgaaaaa atgggcaaat
    12121 tgacaatgaa tgctggacta tttgcttttg aagaaaatgg tacagaggaa gcgaacttca
    12181 tcaatatgaa tttccgtttt ccaaaaggtg taacagtaga cggattgcaa agtgacatcg
    12241 aacaaacagt ggggcaagaa ggcgcaacag ttactcgagg tgctcgcgta atggaaccac
    12301 attacgtacc aatggatgat ccattggtgg ctacattatt gcaagtctat gaagaccaca
    12361 ctggagaaaa aggctacgaa caaatcatcg gtggcggaac ttacggacgt ttgttgaaac
    12421 gtggcgttgc ttatggagcg atgttcccag gatatactga tacaatgcat caagcaaacg
    12481 aatttatgag tcttgatgac ttgttcagag caacagcaat ctatgcagat gccatctatc
    12541 gtttggcgaa ataattaatt aaaaagagga tcaagaattg caaattattt ttgcagtctt
    12601 gatccttttt ttactttcta ctgtggtatt catgataaac atgatataga ttcaattcat
    12661 attctttctt agcgttcgtg acgactgtat ccaaaatcaa ccctgttact aatgaaagaa
    12721 gtgctaaagt catcaatcca gtacttaaaa tcgcagaagg gatgcgtgta ataaagcttg
    12781 tcagcatata ttcgcgaatc acaggaatcc ccgtgaccaa tccaaataaa aagaagaaga
    12841 tggtccaaat cccaaagaaa agcaaaggct tataatcttt aaacatttta ataatcatca
    12901 tgatcacttt gaatccgtca gagaatgtat tcaattttga ttcgctgcct tcaggacgat
    12961 cacgataatc gattgggatt tcaacgaact tgaatttttt atctaaagca tggatcgtca
    13021 attccgtttc gatttgaaaa ccagaactca taataggaaa acttttgaca aagatacgat
    13081 tgaatcctcg atagccggtc atgacatcaa gaatttttgt tttatacatt ctagtaattg
    13141 tatttctaac aaggttattt ccaaaatcgt ggaaaggtct cttattctca tcaaagtagg
    13201 ttccatttga taggcgatca ccaatgacca tatctgcttc accagaacgt aatttctcga
    13261 gcaaaccatg tacagcttct gcaggataag tatcatcgcc atctaccatt aaataatagt
    13321 cggcatcgat atcaaagaac atttggcgga tcacatttcc ttttccttga cgaggttctt
    13381 tttttacgat tgctccacct tgaacggcca attcgtatgt tcgatcggtc gaattattat
    13441 catagacata aatatctgct tctggtaatt ctcgtttaaa gtctgcaatg actgttgaaa
    13501 ttgttgcttc ctcattgtaa caaggaatca gaacagcaat tttttcttgt tgttccattt
    13561 ttcactctcc ttaactatag aaaacaaaag ctaaattaaa aatacctcat aatcaaagga
    13621 aatgctagtt tttcccgcta aatatcattt atttaaaaag aaaatactgg aatatatgtt
    13681 tggaaagctc tatctaaaaa accacccact acaaaagaag gacatgatac ctctcttttg
    13741 aatagtgggt gcgtattcgt tctctcactt ttttgacgta ttaatctgtt gcaccttttt
    13801 ttcttgaaat ttctaatacg gttcctgtat gagcatctgc taaaaattca taataaacag
    13861 tttcgccatc ttctattcga gaaagacctc cccgataagc actcgaccga acggcgaatt
    13921 tcctaatagg ttccttttca aaagagatcc aagaaccttc gattgcacct tcttttagaa
    13981 aagatgactt gatattttca agtacttggt ctgctgacaa tacttttttg cgatgatacc
    14041 aaatcgttga agctaccccg ctcaataatc ctagaccgat tccaactgct aacccgcctt
    14101 taaaatagct tagttcgctt tcttcataca tgtggacata cctccttctt ctcacttgtt
    14161 actccttgtg cttattttac cacactctca tattttcttt gaaataaata accgctacca
    14221 gaaaaaataa gctataataa atacgatcgg tctgcagaaa aaatcatatt ttatccgcag
    14281 atcaatataa gtctgagagg agtttagtct gaaatttaga cgaatagcat atggaagaaa
    14341 aaacatttca acgaatcaaa gagttaacag aattacaagg aacaagcggt tttgaacaag
    14401 atgttcgcgc ttatatggaa agtcatatgg aaccgctggt agatgagtta cagttagatg
    14461 gtttgggcgg catttttggt ctgcgccatc atgaagaagc ggatgcaccc cgtgtaatgg
    14521 tcgcagcaca tatggatgaa gtcggattca tgctgacaca aatccaagaa aacgggcttt
    14581 ttaaagtcgt acctctaggc ggctggaatc cttacgttgt ttctgctcag cgttttacac
    14641 ttaaaacctc tactggtaag aattatccat gtatttcttc ttccgttccc ccacatttat
    14701 tgcgaggaac aagcggacaa aaatcagtag aagtaaccga tattttgttc gatgctgggt
    14761 ttgaatcaag agaagaggca atgagttacg gtgtccttcc aggagacaca atcgttcctt
    14821 acgctgaaac gatcaaaaca gccaacggaa agaatattat cagtaaatca tgggacaacc
    14881 gctatggctg tacaatggta ttagaagctt tagaagcgtt gcaaaatgaa acattaggtc
    14941 atacattgat tgcaggcgcg aatgtccagg aagaagtagg cttgcgtggt tctaaagctt
    15001 ctgtcaataa attcaagcca gatctgttct ttgcagtaga ctgctctgca gcagatgata
    15061 cagtgacgaa aaatggcaca ttcggacatt taggagaagg tacattgatg cgtatccaag
    15121 atccaggttt gatcatgctt cctcgtttgc gcgagtactt gctggatatc gctgaaacaa
    15181 acaatatccc ttatcaatac tttgtttcaa aaggcggtac agatgcaggt gctgctcata
    15241 cacaaaacga aggaatccca agtacagtga ttggcgtagt gggacgttat atccatacgc
    15301 atcaaacgat gttcagtatt cgcgattttg aagctgcacg agaaatgttg attcaaacac
    15361 tgaaaggttt ggataaatca acagtgaata cgatcgtata cggaaaataa tgcgatagtg
    15421 aaactataaa atctggcaaa agattgcttt ttgccagatt ttttttataa aaagaggatc
    15481 aatgtttgtt agttcgaaag aaaggtgtat aatttaattg aaaaatacat aaacagaaag
    15541 tagaggacaa agaatgatta tcccaaatag tttagaagaa ttagcaggct acgtagaaac
    15601 tggaaagagt gtatttttct ttactgccgg ctggtgcgga gactgccgtt ttatcaaacc
    15661 gcaaatgcct gaaattgaaa atgacttttc tgattggcaa tttattgaag tagaccgtga
    15721 caagtacata gatgtagccg ctgaatggaa catttttggt atcccaagtt ttgtcgtgat
    15781 ccaagacgga aaagaattag gtcgtctagt gaataaagat cgtaaaacaa aacaggaaat
    15841 cgaatcgttc ctagaaagtg taacaaaagg ctgacatctg ttaggagggg tcaagatgaa
    15901 tcaagaatat aagaatattt tagtaggtat cgacggtagt gaacaagcac ttgctgcttt
    15961 caaaaaagcg gtagaagtgg ctcgccgtaa taatgggaaa gtatatgtag caaacgtaat
    16021 cgatcagcaa ttttataact ttatgggcta tgcacctatt gatcaaaatc tagtcgatca
    16081 gcaaactgaa acagccaagg aaatgatcga agaatgtaaa gaatatggga aatctgttga
    16141 ttacacaaat atagaaggaa ttattgcata tggttctgtt cgtgaatcca tggcagtcaa
    16201 attgccaaaa aaatatgaga tcgatctaat catggttggg cagtcaggtc taaatgcagt
    16261 cgaacgcttt atgacaggaa gtgtagccag ctacgtgata cgtcattcac cttgtgatgt
    16321 cttgatcgtt tctgacgaag aagaacagcc aagtaattaa gcaagtggaa cttgtacgac
    16381 ctttttaatc aattaactaa aacagtaaag ggactgtgac aaaagtcttg tcacagtccc
    16441 ttgttacgaa taaatggtgt tccagaagag gcttcttcgg aaataaagca tgaaaaaaat
    16501 ttcatgcagt gaatgcaatt ttttgttaag ataaatctca gcaaaggata atggaggaaa
    16561 gaacatgatt tttgcttata acaaagcaca cgtcggagac accttgatgg ttattatagc
    16621 cgacgataaa ggaacagaaa acactgttga acgcaaatgg aatgttgctc ggatcaaaga
    16681 tgaacaaggt caagttgttg cttggaactt tttccatatc tccgatcatc taacaatcga
    16741 agggaacggc caagtaagct taacagatga ggaattagcg aaattgaatc gattgatcaa
    16801 agaagcagga ttcgaagaac agcttgaagc tgatcatgaa ccgaagatcg ttgtcgggta
    16861 cgtaaaaaca tgcgtcccac atcctgattc tgaccattta tcgattactg agacagaagt
    16921 agacaatggt acagtattgc aaatcgtttg cggtgcaccc aatatcgaag ctggacaaaa
    16981 agttgtcgtt gcaaaaccag gagctatgat gccagatgga atgatgatct ggccaggaac
    17041 tttgcgaggg gtagatagct atggaatgat ctgttccgct cgtgaattgc atttgccaaa
    17101 tgctccagca aaaaaaggaa tcttagtatt gcctgaggat gccgtagtcg gagaagcatt
    17161 tccaaaataa agaggttgtg acaagtcttt gtcacaacct cttttttatt aattttcact
    17221 attttgattt tgttttaatg ccgattgatc gatcgtcaat tcaacagtag ttgttttttc
    17281 tttcgagcct tcatagtaag tgattttgac agaatctccc acttttttct tatacaaagc
    17341 agattgaagt tctacaccag aagaaacttc tttgtcatcg atcttagtaa tgacgtcgta
    17401 ttgtttcaat ccagcttttt cagccggtgt agctgtttgg acatttgtca cgatgacacc
    17461 gttagttaca gatgaaggaa tcttcaagat ttgttcttgt tgctgagtag aaacggcaga
    17521 taagtcgacc attgtgatac ctagagctgg acgtgtcact tttccgtctt tttccagttg
    17581 attgatgata ttcactacat cgttacttgg aatagcaaat cccattcctt ctacgcttac
    17641 attagaagta gattcagaag tacttgcgat cttacttgag ttgataccga taacttgtcc
    17701 ttcgatatta actaaaggac caccagaatt tccagggttg attgctgcat ctgtttggat
    17761 cgcattgata ttgactgttt cgttcgattc attcgtactt gtcacttgtc ggttcaagga
    17821 agaaatgatt cctgaagtga cagaatttgc atattcagat cctagtgggg aaccaatcgc
    17881 aatcgcaggc tcaccaacct tcagagcact tgagtcacca aaagaggcaa ctgtttcgac
    17941 tttgtctgaa ttgatcttca acaccgctaa atctgaataa gcatctgttc caactaattc
    18001 agcttttacc ttcgtaccgt ctttcatcaa gacttcaaga ccttgctggc catctactac
    18061 gtgattattc gtgactacat aagcagtatt cccgtctttt ttgtagatca cgccgcttcc
    18121 ttcactataa gcttccaaat tactatcatc tgagctgcta ctttcttctt gctgcccgaa
    18181 tagtccgcca aaaccgcttg attggttttg actttgtaag ttgataacag aaacgacagc
    18241 gtcttgaact ttatctaccg ctttggtgat atcagaatct acattgactt tgacattttc
    18301 cacaactgtt tcaccggcag aattctgatt gccgcttgta gcagtagaac tattgttgcc
    18361 agtgcccatc gctgcataaa aaatgccagc tgtcagtagt cctccaacga tccctccaac
    18421 aagccccaga cctaacttac gccagaggct attattttta ctttttttca tctttggtgt
    18481 cacatttttt ctatccatgt gttcctcctc caattacatt catttatcta ctgttagtat
    18541 agtcttattt gttgacttta gtctactttg agactgtgaa ctttttatga aaaactttag
    18601 gaaaaatcat tgttttcaga tgaaaatatt tgattttctt tttccacaga tactgtgtaa
    18661 aactacgcgg ataggattgg aaaaataagg gataaaacat atccacagcc tgtgtataaa
    18721 gtggataaat tcttataaaa cgtatgtttg cctaatgaat gtgatgaaat aaggtaaaat
    18781 aacactgttt tctgtggata aacctgtgga tgttgtgcat aactgttggg gaaatctttt
    18841 taacaaaaat agccaaaata aacatataga cgaaaaaatt gattataata aacaaagtga
    18901 gcatgaagac caaaggagag aaaacatgaa tatcaaaatt atctcagtag gaaaattaaa
    18961 agaaaaatac ctgatccaag gtatcaatga gtatgtcaaa cggctgaatg cctatgcaaa
    19021 aatcgaattg atcgaagttc ctgacgaaaa agccccggag aatttaagcg aagcgcaaat
    19081 gagacaagta aaagaaaaag aaggggaacg gatcttagcg aaaatcaaag aacaagaata
    19141 cgtctatgcc ttagcaattg aagggaaaaa tcctacaagt gaatcttttg ctaaacaaat
    19201 cgaccaatta ggtatccaag gaaaaagcca ccttgttttt gttatcggcg gctctttagg
    19261 actcagcgaa gccgtcatga aaagaagcaa tgctcagatc tcttttggaa aaatgacgta
    19321 tccacatcaa ttgatgcgtc tgatccttgt cgagcaaatc taccgtgcct tccggatcaa
    19381 tgcgggggct ccgtatcata aataatgata tttaagattg aatgctcctg aacactaagt
    19441 tagcttttca ttgaaattta tatataaaaa agttaacttg aaaatcgttg agaatttcaa
    19501 aaaaataata ataactttat tatgtattca aatttgttac aaaaaattga agatgaagag
    19561 cg
//
LOCUS       DAFLWQ010000048        19545 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.049, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000048 DAFLWQ010000000
VERSION     DAFLWQ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19545
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.049"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(462..1091)
                     /gene="udk"
                     /locus_tag="L1V16_001767"
     CDS             complement(462..1091)
                     /gene="udk"
                     /locus_tag="L1V16_001767"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBN1276109.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1175..1870)
                     /locus_tag="L1V16_001768"
     CDS             complement(1175..1870)
                     /locus_tag="L1V16_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBN1276110.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1883..2599)
                     /locus_tag="L1V16_001769"
     CDS             complement(1883..2599)
                     /locus_tag="L1V16_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HBN1276111.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2929..3534
                     /locus_tag="L1V16_001770"
     CDS             2929..3534
                     /locus_tag="L1V16_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HBN1276112.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3859..4182
                     /locus_tag="L1V16_001771"
     CDS             3859..4182
                     /locus_tag="L1V16_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBN1276113.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4364..5734
                     /locus_tag="L1V16_001772"
     CDS             4364..5734
                     /locus_tag="L1V16_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBN1276114.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5864..7165)
                     /locus_tag="L1V16_001773"
     CDS             complement(5864..7165)
                     /locus_tag="L1V16_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBN1276115.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7395..9353)
                     /locus_tag="L1V16_001774"
     CDS             complement(7395..9353)
                     /locus_tag="L1V16_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HBN1276116.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9530..9796)
                     /locus_tag="L1V16_001775"
     CDS             complement(9530..9796)
                     /locus_tag="L1V16_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBN1276117.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10306..12432)
                     /gene="pnp"
                     /locus_tag="L1V16_001776"
     CDS             complement(10306..12432)
                     /gene="pnp"
                     /locus_tag="L1V16_001776"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBN1276118.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12620..12889)
                     /gene="rpsO"
                     /locus_tag="L1V16_001777"
     CDS             complement(12620..12889)
                     /gene="rpsO"
                     /locus_tag="L1V16_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBN1276119.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13140..13703
                     /locus_tag="L1V16_001778"
     CDS             13140..13703
                     /locus_tag="L1V16_001778"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBN1276120.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13956..14477)
                     /locus_tag="L1V16_001779"
     CDS             complement(13956..14477)
                     /locus_tag="L1V16_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBN1276121.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14480..15322)
                     /locus_tag="L1V16_001780"
     CDS             complement(14480..15322)
                     /locus_tag="L1V16_001780"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HBN1276122.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15315..16040)
                     /locus_tag="L1V16_001781"
     CDS             complement(15315..16040)
                     /locus_tag="L1V16_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBN1276123.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16216..16512
                     /locus_tag="L1V16_001782"
     CDS             16216..16512
                     /locus_tag="L1V16_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276124.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17080..18672
                     /locus_tag="L1V16_001783"
     CDS             17080..18672
                     /locus_tag="L1V16_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBN1276125.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18685..19425
                     /locus_tag="L1V16_001784"
     CDS             18685..19425
                     /locus_tag="L1V16_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBN1276126.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5590 a         4006 c         3712 g         6237 t
ORIGIN      
        1 tagggggtgc gacaaaagag cttcttcaaa aaaataagtc gaaatctcac acaaattcga
       61 gaaataattt tcgtaagttt cttcttattt attgcatctg accacttctg ttacaacctc
      121 tcgttaaacg gtgttcaaaa gcttgcatct acgataataa gcccaaccca acgaaaaacg
      181 tgaggagctg ttttatttgg atgctcttat cgcttgatgc aaagacagct tttttacaac
      241 ctctacttca cggtgctcaa tcagctgacc ttcggtatta gctcaaaaaa cggtaaaata
      301 taaacagcta ttttccgttt cttcttttta atacttaggt caagatgctg ttttcacaac
      361 ctcttgttat aaataaaaaa aacagttggc tggtgactgt tcaaaaagca gaatccttgc
      421 ttttcaaacg gtcgcagtcc gttcaactgt ttcgctgcgc actatttatg gtttaagaaa
      481 ctagctactt ttgttgtaat caaatcaata gcaacgtggt tttctccgcc ttctggaaca
      541 atgatatccg catagcgctt cgttggttcg ataaattgat gatacatcgg tttaacaact
      601 gtcaaatatt gttcgatcac ggagtccaat gtgcgtcccc gttcttccat atcccgtttg
      661 atacgacgaa tgatacgaat gtcatcatct gtatctacgt atactttgat atccatcaag
      721 tcacgcagac gttcgtcttc taaaatcagg attccttcta gaatgatcac ttcttttggt
      781 tcctgaatga tcgttgcctg acttcttgta tgcgctacat agtcatacac gggtttttca
      841 atggctttat agttcagtaa gtcgcctaca tgctgaatca gcagatcatt atcaaaggca
      901 aatgggtgat cgtaatttgt gttcaatcgt tcttcaaaac tcaaatggct ctgatccttg
      961 taataagaat cttgttcaag catcatgatg gaatggtccg ggaagttgtt gaaaatcgca
     1021 cggctgacac ttgtctttcc gcttccggat ccacccgtca caccaatgat aattggcttg
     1081 ctttttgtca ttgactaaaa cctctttcgt atccgttttt tcattctaat ctattatagc
     1141 gaaaaaacac gaaaatgcta tatttttctg aaaattaatc cttttcaatt tccaataatg
     1201 aataaagttc ctctaatgaa tcgattcgat aagtaggctg gatttcttcg atttctggta
     1261 atttatttct attgaaccaa atcgtatcga tccctgccat atttcctcct ttgatatcag
     1321 aagtcaaaga atcaccaatg atcacagttt gctttttatc aaaattagga atgtgggaaa
     1381 agacatgatc aaaaaattct ttcatcggct tttgcgctcc gacagcttct gagacaaaga
     1441 tatccttgaa gtaatcaagc attcctgcat ctgttaatcg ccgatgttgc gtgtgcgaca
     1501 caccgttcgt cacaatataa agatcagcat gcggatggac ctttttcagg atttctagac
     1561 ttcctggaac aagatcatga ccttggttca agtagtggcg gtagcgtttt tccatttgat
     1621 cactatctac tgttttccca aattgctgga aaagtaaccc aaaacgactg cctattattt
     1681 cttctcgtga tagtctgcct ttttcaaact cctgccataa atgatgattc aaagccttat
     1741 agctggtttc gatttctggt gtcaatgtga ttccttgttc tgcaaacaaa gcacttaaag
     1801 cattggcttc agttaattga aaatctaaca atgtatcatc tacatcgaac aataaagttt
     1861 tatatttcat ctttttgacc tcctatttaa aataaatact taactttttc atctctgcta
     1921 atgtcaacga tcgatactcg cctactccta gctgttcatc taattccaat ggtcccatgc
     1981 ttagccgttt caatgcggtc actttctttc cttgggctaa gaacatcttt ttgacttgat
     2041 ggaattttcc ttcttggatc gtcaataaaa ccgtactttg gtgcttgtct gctttgagta
     2101 tttttaaatc agccggctta cattgatacc catcagcgaa tacgattcca ttttcaaatg
     2161 ctgttacgtc tgccggtgtc accctttcgt tcacaactac ttgataagtc tttgaaacct
     2221 ttttttctgg aagtagcatt tcatatccca attgtccatt cgaagtgatc agcaatagtc
     2281 ctgttgtatc tctatctagt cttcccactg gatataatgg ttggaaacga tcggcacttg
     2341 caatcagatc gattactgtc gtcttttctg gatctgatac agctgtaaca gctttttcag
     2401 gtttattgag aagataatag gactcatttg tttctaagtg ttcacctgct acttcgattt
     2461 gatgcagtaa actatctaca tttcgatttt gtcgaaattc gactgtgcca tctatcatca
     2521 cttgcttcaa agcaaacagc cgcttcattt ccttgcgtgt cgtttctaat ttttcttcta
     2581 ttaatttatc taaacgcatg ctgtttcctt tcttattact actaattaat tataccttga
     2641 atattcttgc ttgcaaatac atcatcatag ttattccttg acttaattaa cagttcacgt
     2701 tacggttaaa tagtaaagtg aattggattt ctcatacaca gcgtaatgac ctggtggaga
     2761 aaagttgaat cctgactttc taaggggaga tgcgcgcatc tctccttttg cgctttttta
     2821 agcgccctgc cttcgatgat gtgcacgaga ttagccttta gaattcactt aaataaaatc
     2881 tgtccgttac caaagcagac agtcacattt taaggaggaa ttttggttat gtcagtatca
     2941 ttagaagtaa gtaaaagaga agtacgtccc cgttcattaa gaaacaaact tcgtcacgaa
     3001 gggaaagttc cagctgttgt ttatgggtat aaagtagaaa gtacccctat ctcattcgat
     3061 ggtttgacac taagcaaatt gttgcgtgaa catggagcga acacagtcat cacgatggac
     3121 atcgatggac aaaaagtcaa tacattggtt cacaagatcc aaacgaacac ttttaccaat
     3181 catttcgaac atgcagaatt tctatctgta aacatgtcgg aagaaacaga agtcgaaaca
     3241 gaagtcgttc ttgttggcga atcagtgggt gctaaatctg gtggagtgtt agctcaaaac
     3301 ttgtatacag tagtcgtatc tgctacacca gacaaattgc ctgaacgaat tgaagttgac
     3361 gtgacaaact tggaattagg tgattctatt acagtagccg atcttccaaa aaacgacgat
     3421 tacaaattcg tgaccgacag tgaagagcaa atcgctgctg tagtcgctca aagtgaagaa
     3481 gaaagcacag gtgaaggtgg cgaaccagaa gtgatcggtt caacagaaga ataatactga
     3541 aacaatcagg tggtgttaga agcggcgggt cagcagcttt taacacgcct tttttatttc
     3601 taatcgttta ttttcatatg gggcttccac ttttgtaaat ggctttacaa acgaaaaatc
     3661 ctaatttacc aagcttttcc tcgcatactt ttatcgtacc tttataaaaa tttatacttt
     3721 gaaaaaaagt attcaattat tgttgcattt ttcctgattc tttattagaa tgaaccctcg
     3781 ttgaagtaag tatttctagt ttatcctagg attaattata aaaataaaac attcgttgat
     3841 tcgaaggagg ttaaacagat gtttgaaagt tttgatagca gccgcaaccg ttacgcttca
     3901 gttggtgtcg tatcaagttt gccagatgaa ttgattgaca gtatatggtt tattattgac
     3961 ctagatctta agggagtcat tccattagaa aatatattaa cctttgattt gatcgaaaat
     4021 cgtggaaaag tgacgatgca tttttctcaa gcaggaagca atgtggaaat ggatattgat
     4081 ttgccgtttg cctattcgaa ccaatttcct gctcaagtat acgcctatga tgacggtacg
     4141 agagaaacga tccttttacc aagtgagatt agacaatatt aaggtgatag ataaacgtgg
     4201 atgtccctta ttttacagac caggccaagt tgttgattct ttgactcaat tcttggcttc
     4261 tttttatgga gtttcataaa ttatcattga tttctaattg gtattctcag gataaacgct
     4321 atatactact aactaaattt taaagatata aggagtttaa aagatgcgcg atttaacaaa
     4381 aggaagcccc gctaaactga ttttgatgtt cactgttcct ttactgatcg gaaatgtttt
     4441 tcagcagttc tacaatatga tcgatatgat catcgtgggt cagacgctag gtaaaaatgc
     4501 gctggcagcg gttggtgcaa ctggaagcct gacatttttg atcattggct ttgcccaagg
     4561 tttaacagct ggtttagcca ttattaccgc acaacgttac ggtgcaaaag attatcgggg
     4621 tctgaagaaa agttttgctg ctagtgttgt cattagtctt gtcgtcactg tgattttaac
     4681 tgtcctaagt ctcctgttta ttcgtccgat gcttcaattg atgcaaactc ctcctgaaat
     4741 acttgatcaa gcacaaacat ttatttcaat tattttatta gggatctttg catcagtcag
     4801 tttcaatttg ctttctaatg tcattcgcgc acttggtgac agccgcacac cactattctt
     4861 tctgatcatt gcggtcatca tcaacgtcgt acttgatttg atctttatta tctattttgg
     4921 catgggtgtg gaaggtgcag ctattgctac agtaatcgca caagtttctt ccagcgtact
     4981 gtgtctagtg tatatcaaga aaaaaatgcc tttgttacag ttacgcaaaa aagatttcaa
     5041 atttgaaaaa gaagagtttg ctgtacacct aaatgctgct ttgccaatgg cgtttcaatc
     5101 ttcgatcatc gctgttggtg ctatcgtgtt acaagcagca ctaaatagtc tagggacaga
     5161 tgtcgtagct gctcaagccg ctgctggtcg tatcgaccaa tttgcaaatc agccgatgat
     5221 gtcatttggt attgcaatgg caactttcac tgcacaaaac tatggtgcga aagaatatgg
     5281 ccgaatcttg caaggggtac gtcaaacttt actgatgagt gtcggattta gtctcttagc
     5341 aggtgctatc gtcattttct tcggtcattt ctttgttcaa ttgtttgtta gcccatcaga
     5401 aacacgtgta tttgaattag cacaaaccta cttcaatatc aatgggtctc tttactggat
     5461 cttagcagtc ctgttcattt tacgctacac acttcaaggg cttggacaaa gcaagatccc
     5521 tacgatcgcc ggtatgatgg aattgcttat gcgttctttt gcagctatcg ttcttacagg
     5581 aatgtgggga tacccaggag cagcagcagc ttctccttta gcttggatcg gttctgttgc
     5641 cgtgttgctt tactcttata tgcgttcgat gaaacaattg aaacacatgg gtgaagagga
     5701 acatttcaca ttagaacatg cagaagcaag atagccttga ttaaaagaaa tcgttgcggc
     5761 taaaaatgaa aacttttatt gaaaatatct tcttcgttta ccgaaaacag gttttttaga
     5821 taacaaaaag gctgtgacaa aaaatgtcac agcctttttt cttttattct atttttcttt
     5881 ccgtggactc tactttgaaa taatcgatat gtgcatgctg gtattctaat accgtgaaac
     5941 ggaatgatgc aatctcaatg attgttcctg cttttatttc tttatatcgg ctagaagcaa
     6001 agcccgcaag tgtagtaaaa ttcgtttctt caaactctgg aatctctaca tgaaaataac
     6061 gctggaaatc atctaatgtt agtttgccgg agatgatata agagccatct gactgttccg
     6121 ctatcaatgc ttcgtccaaa tctgtctcat ctcggatttc cccgacgatt tcttctaaaa
     6181 tatcttcaat cgtcactaag ccgcttgtcc ctccgtattc atcttttaag atagcaatat
     6241 gctttccctt ttttcgcatg atcgtcaata atttttttat agggatcgtt tcagttgtta
     6301 cgatcggctc ttcaatcaac tgttctactg tcagctggtc atctttataa gattgcttga
     6361 tcaaatctgg caaggtgaca taacctaaaa cattgtcttt tgattctaag ataaccggat
     6421 agcgagtatg tccttgttca atcgaagctt ttatcgcttc tttgacggtt tctgaagctt
     6481 cgaatacttg catggacgta cggtctactt gtatatcttt tgccaaggta tcatcaaatt
     6541 caaacacgtt ttccaaataa tgatattctt ctttggtcaa ctctcctttt tcataagaat
     6601 tcaatgcgac taatgtcagc tcttcttgag acaatgtctc ttctccttca gatacgagac
     6661 gcacacctaa tagcttccct agccctgcag ctgaatgatt caatacccaa ataaaaggaa
     6721 acattacttt ataaaaataa tgaagtggtt taactacgaa caagacgacc ttctccgtat
     6781 tgacgatact atagctctta ggaagcagtt cgccaataac cacatcgata tacgtaacta
     6841 aaataaatcc cagcgccaca gagattgtac tgctaatagc cgaactaaaa ggtagtttac
     6901 cgatcactgg ttctagtaaa gccgcgacag atccttcacc gacccacccg atgatcaaac
     6961 cggttagcgt aattcctaat tgactagctg ataaatagtt atctaaatgg tgtgtaacat
     7021 gaagagctag cttggcgttc tttacatttt ccttttctag ttgttccaat cttgatcgtc
     7081 tgattttcac taaagcaaat tcacttgcta caaaaaatga agtaattgca atcatcaaaa
     7141 ataaaataat gaaattgata accatattct cccgcctttc tctttttcta ttgtaccctt
     7201 tttctacaaa aagattgaaa ataatgcgta ttcatattta ggaataaaaa aggagatgcg
     7261 gcatttttca gccacatctc cttatcactt caaaatcatt gcgttacttg ttgctaaaca
     7321 gctttttcat gacctctgat aaacggtgtt caagtagctg acattcgaca ttagttcagg
     7381 tcaaagcgct actttcacaa ccgctctttc aaccatgttt tccgagtatt tccaatgata
     7441 agcggaacag tttcatgttt tacttcgctg tactctagcc caaaccatgt ttctggcgag
     7501 gtagcgattt ttttgattgc cagttttgcc tgcatgattt gacgttgcca ttttcctaga
     7561 gttgtcacat tggaaactac ttcatcaatc aggacaaatt ggaaatcgcc aacttctcgc
     7621 cctggtgtca gagagtatct ttgtggctgt tttggcaaac ggccttgttt catcaaatca
     7681 tggatgactt ggcgaacata tacgttgatt tcctgttgga ccctgaaacc taagaacaga
     7741 ttcacttgga caataaaatc agtgtccatc atatctactt gatattcttt cgtatatggc
     7801 tcatccgtca cttccacatg aacaaaccaa tagactcgtg ctcttttagg ccgtttatct
     7861 aaaatcgaat agatgaactg tcggccaact ttatcttcag ccatatcagg aaccaagaag
     7921 accacatttg tctgatagat tggtaaagaa gtatcatcac gtaattctct aagctgcggg
     7981 atataatctc tcaaagacac atcctcggtt gacgattcgc gaataatgtt cccttgttcc
     8041 caaataaaca tcacgactaa gatgatcaaa ccaatcagaa cggctacaaa accgcctcgg
     8101 aagaatttga caacacttga gataaagaaa acgacttcta tcgcaccgaa gaaaaaggta
     8161 actaaatatg caagccaacg agaatgccca ttttggataa gataaaagta aagcagtgct
     8221 gttgtcatca acatcgtcac agtgatcgat agaccgtaag cagcttccat atgatgagac
     8281 gttcggaatg tgacaaccac tagagaacag gcgatccata aaatcagatt gactgctggg
     8341 atatacattt gcccgatact gttcccagga tacatgatct ttaaccgagg cagcagtttc
     8401 aacttgattg cttctgaaac tagcgtaaac gaacctgtaa tcaatgcttg cgaagcaatg
     8461 actgcagcga ctgttgcaaa agcaacgccg atcacgatcc aactttgagg catcatttgg
     8521 aagaatggat tcaggttctt gatttgctgt gcttcagggt tttgataaac attcaacaac
     8581 cacgcagcct gcccaaaata attgataacc aaacaaattt tgacgtaagg ccagctcaga
     8641 cgaatatttc gtttgccgac atgtccaaga tcggaataaa gcgcctctgc acctgtcgta
     8701 gccaggaaaa tatttccaag aatgaacaag cctaatttgt tatctgcact aaaaagcagc
     8761 tggatagcat aataaggatt cagtgcacgg ataactgtcc agtcttgact gaagttcatt
     8821 aatcccatta cgcctaaaaa agtaaaccaa gcgaacatga ttggtccgaa tgcttttccg
     8881 acaatatctg taccaaagcg ttggaccatg aataaaacaa aaataataac taaagtgata
     8941 atgacgatca cgttctggtt attaccgaac cggtcaaaaa actgcggaat tcctcgcaag
     9001 ccttcaatcg cagtcgttac cgtcacagca ggggtcaata ccccatctgc tagtaaggca
     9061 gctcctccga tcattgcagg aatgatcaaa tatttcccac cttttcggac aagtgtgtag
     9121 agtgagaaaa ttccaccttc accatggtta tctgcattca atgcaatcac gacatatttg
     9181 attgttgtca gtagagtcaa tgtccaaaaa atcaatgaga ctgatccgat aacaaaatca
     9241 ggattgattc ctgacaatcc gccattatct tcaacaatcg atttcataac gtaaagcgga
     9301 cttgtcccga tgtctccgta gacgactccc atcgctacaa gcaggccagc cattgatatc
     9361 tttttggtat tgtgcgttgt tgccacgttt ttccctcatt tcttgttata tggatatcct
     9421 ttaggtaagc ttgaatgata gatgatattc ttatccatga cacccgcttt cctaaattgc
     9481 ttctaattat ccaagtaaca cactgaagtg tcaacttatt tgaataaaat tattctttct
     9541 ttggacgttc tctgatacgt cttgccacaa atgaataaag agcaaggcaa aaaattgcac
     9601 ccaataatgc tggtatcaaa taaaaaccgc cgagttccgg tcccagtggt cctagtaaaa
     9661 attcgccgag ccaactacct aaaaaaccga taatgatatt tccagatacg cctcccggga
     9721 cttcctttcc taaaattgcg ccagctatca aacctaatat accgccgata aataacgacc
     9781 ataaaaaatt cagcatctcc tttccctcct ttatccatat ttctcacttt tattttacgc
     9841 tttattcaga aggactccaa aaatatgcgc caagaaactc cagaaaaaaa gaagttgtaa
     9901 caaaagtgtt cagcttattt ccgtagaagc tgcttctgga acaccgtgaa tcagaggttg
     9961 tgaaatcagc ggtttgacct gagtattaga gaaacaaacg gaaaaatagt tcctcatatt
    10021 ttgccgtttt ttgagctaat atcgagggac agctgattga acatcgttta ttggagaggt
    10081 tgtaaaaaag ctgttctgca tcaagtaata agaacagcca agtaaaaaca gctcctaatg
    10141 tttttaactt ggctggactt attaccgcag atgcaagctt ttgaacaccg tttattcgaa
    10201 aaaaaaggac tgtgacacgg cttttgtcac agtccccttt tttcgaataa ttattgtccc
    10261 cctgtcacct tcacgatcac aagtacatta ttcctatgaa ttaaattatt tttcttcatt
    10321 tttcgttgaa ccatcttcgt tcaacattgc ttttcttgac agatttacgc gtccttgttt
    10381 atcgatttca gttactttca caaggatctc atcacctagt ttaacaacat cttcgacttt
    10441 attgacacga tcgtttgcta attgggaaat atggacaagt ccatcttttc ctttgatcaa
    10501 gttgacgaat gcaccgaatt tttcgatacg gacaactttc cctagataaa cttcaccaac
    10561 tttgacttct ttggtcaaat cttcgatgat cttgatagct tttttgatca tttctgcatc
    10621 agctgaagca atacttactt ttccatcttg atcgatatcg attttcacac cagtttcatc
    10681 gatgattccg ttgatcgtat cgccgccttt accgataaca tctttgattt tagcaggttc
    10741 gatctggatc atttcgattt ttggtgcata ttggcttaat tcttcacgtg gagcagcaat
    10801 cgttgaagtc aattcttcta agatttccat acgtgcttgt tttgcttgag ttaatgcttc
    10861 agttaggatt tgttctgtga ttccttgaat cttgatatcc atctgtaaag cagtgatacc
    10921 atcttttgta ccggcaactt taaagtccat atcgccaaga tgatcttcca gcccttggat
    10981 atcagttagg atcgtatagt tttcaccatc agaaacaagt cccatcgcaa taccggcgac
    11041 tggcgctttg attggtacac ctgcatccat caatgctaat gtgccagcac agatacttgc
    11101 ttgggaagaa gaaccatttg attccaatac ttctgctact aaacggatcg tataaggaaa
    11161 ttcttcttct gaagggatta cttgtgctaa cgcacgttca cctaatgcgc catgtccgat
    11221 ttcccgacgc cctggagagc ctgcacgtcc tgtagaacca acagaaaatt gagggaaatt
    11281 gtagtggtgg atgaatcgtt tgctgacttc cacccctaaa ccatcaatga tttggtgctc
    11341 tcctagaggt gcgagtgtac aagctgataa agcttgtgtt tgtcctcgtg tgaacaaacc
    11401 tgatccatgt acacgtggca ataagctgac ctctgatgac aatggacgga tttcatccaa
    11461 tttacgcccg tcaggacgga tcttatcgat ggtgatcaat tcacgtacga catctttttc
    11521 aagatcttct gtgatttgtt taacttcttt caacaagtga tcttcatctt catgacctgc
    11581 aaatttctca gcataagctt cgcggatatc gatcttcacc tgctcgatat tatcttcgcg
    11641 agcaagtttt tcttcagtca ttactgctgc tttcattgta gcgtaagaag catcaaagat
    11701 ttcttttttc aatacttcat caacttgcag taaagtcact tccatttttt ctttccctac
    11761 tgcttgaacg atttcttctt ggaaagcaac taactctttg atagcgtcaa aaccaaacag
    11821 caatgcacca agcatgtctt cttctgaaac ttctttcgcg ccgctttcaa ccatattgat
    11881 ggcttgtttc gttccggcaa cagtcaattc gatatctgtt tgttctgctt gttctactgt
    11941 tggattcaag acgtactcgc catttacacg accaacttct acgcctgcga ttgggccgtc
    12001 aaatgggata tctgagattg atagtgctaa agaagaacct agcattgctg ccatagctgg
    12061 cgagcagtct gtttctacac tcatcacgat gttcgttact tggacttcat tacggaagcc
    12121 ttctgcaaac atcgggcgaa ttggacggtc gatcaaacgg gcagtcaatg ttgcttccgt
    12181 acttggacgg ccttctcgtt tgatgaaacc tccagggatt ttccctgctg catacatttt
    12241 ttcttcataa ttgatcgtta atgggaaaaa gtctgtatct tttgcttctt tagaggccac
    12301 agctgcactt aagactactg tatctccata acggactaaa acggctccgt ttgcttgttt
    12361 tgctagctga ccgacttcga tttgtaaggg acggccgccc catgtcgttt tgaatacttg
    12421 tttttctgac ataacttctc cttttccttc tcgtgaaagc aagacgctac taaacaaatg
    12481 aaaactgccg aaagccgtct tttgagcagc tttcatttgg ttagtaggag tccatctagc
    12541 ttgatcacgg aattttactt aattgatata cgagtaaaaa aagtgagatt catgtgaatc
    12601 ccactctttt tgactaaaat taacgacgca agcctaaacg tttgatcaat tcgcggtaac
    12661 gttgaacgtc agttttacgt aagtaagcta acaagttacg gcggtgacca acttttttca
    12721 ttaggccgcg gtatgaatga tggtcttttt tgtgcacgcg tgcatgttca ttcaagtggt
    12781 tgatttcttc agttaataca gcgatttgta cttctggaga accagtatcc ccttcatggc
    12841 gagcgtattc gttgatgatt tcattcttgc gttcttttga aattgccatt tctttcacct
    12901 ctttcgatta ttcccctgcg actgagtaaa acgttggtga ttcgcttaac caagtggcag
    12961 gtcatgtgcc tagagcacac agctatactt tacctgaaac cgggttgaaa atcaagtagt
    13021 taatcattaa gaaaaggtag ttttcaaaca atcttactac tacttttcca tttttgtggt
    13081 aaactataat gcgaaaatag acttgaaaca cagtctttta agaaaggggt acatattcca
    13141 tgattacaat ggatgatatc attcgtgaag gaaatccgac cttacgcgaa gttgcaaaag
    13201 aagtttctct tccattaagc gaagaagata tctctttagg aaaagagatg cttgagttct
    13261 taaaaaacag ccaagatcca atcaaagctg aagaactaca cttacgaggc ggtgttggct
    13321 tagctgctcc tcaattagat atttctaaaa gaatcattgc tgttcacgta ccaagtcctg
    13381 acccagaggc agatggacct tctctaagta ctgttatgta taatcctaaa attttgagcc
    13441 attctgttca agatgcttgt ttaggggaag gtgaaggctg tttatctgtt gatcgagaag
    13501 taccaggata tgttgttcgc catgccaaaa tcactgtgtc ttattatgat atgaatggtg
    13561 aaaaacacaa gattcgtttg aagaattatg aatcgatcgt cgttcaacat gaaatcgacc
    13621 atatcaacgg tgtgatgttc tatgaccaca tcaacgatca aaatccattt gcactaaaag
    13681 aaggcgtatt ggtgatcgag tagagaattg gcaggttcct tcgatactat gctacaagaa
    13741 agctttataa aaaaggggag tgctcaaaag ctgcacttcc cttttttatg tttctccact
    13801 aatcgaaatt tagatagaca tctagaaatc gcaattccaa aaaattctgt gtattggata
    13861 cgcatctttt cttatttttt cttatttctt ccatatgggt gtttatctca gagatgatag
    13921 aatagtttct aggataaaaa gtagcagcta cgatgttatc cttcgtagag gattcctgct
    13981 tcagctagtt tttgtttgat gtttttcagc atatgctttt ctgggtagcg gatcgtatgc
    14041 agatggatgc cgcctgttaa ttcggataac aaagtagcat tacttttttg ataacgtctc
    14101 ataaaggaat cgatatcttg tggcgttttg atgtgcaaag ttcctgctaa ctcaccgtaa
    14161 aggggatgtt ccacaattac atcaatgatt tcaccaccat tttcaacgat tagtctcagt
    14221 tcttcttctg tttgatcttt tccatgctgg acagcgattt tactgatgtg cccagtattg
    14281 gtttcttctg tttcgaggat ataacctctt gctgttgcca cgatactttt acctgcagct
    14341 cgtagtaaag caatatcgcc tacaatgatc tgacggctga ctccaaaagt tttcgcaaac
    14401 ttgctagcac tcactggttt ttctgtattt gccaaggttt gcatgatttg ttttcgccgt
    14461 gtctctcctt cgatcacact tattcctcct tcattttgtt ttggtattcg cgcgagtgtt
    14521 tcatcaaatc aacatacgtg tctgttattg tttccttata tcccttattt ttcagcagac
    14581 taacaacttt atccaatact tgctgctctc tttttgcatc ataaactgct tggttttctt
    14641 cttttttcac ttgtcctatt ttagttaccg tatccattct tttttctaat aaagcaacca
    14701 actctcgatc gatcatatcg atcttatgac gtaatgtttc aagagactct tctgttagtt
    14761 cttcctctac tgtcttgatg atacgagcag gatttcctgc aatcactaca ttgtcgggaa
    14821 aagatttggt cacaaccgaa cctgcgccga ctactacgtt gtcccctaga gtgacacccg
    14881 gcgtgacgat aactcctccg cctaaccaaa cattattacc gattttaatg ggttttgcgt
    14941 actccagacc gctgttacgt ttcactggat gtagtggatg cgtcgccgtg taaagctgga
    15001 cattcggagc gaacatgcag ttatcaccga tttcaatcgt gctgacatct aaaaatgtac
    15061 aattgaaatt tgcataaaaa ttctccccaa caaatatatt atatccgtaa tcaaaattga
    15121 taactggctc catatagatt tttttccctg tacggccaaa agtctctttc aacaattggg
    15181 atcgcagttc cgctgattct gcttggttga tgatttggct ttgacttctt gcaaacatac
    15241 ggtcggcaac cagctcagga tcattggcaa aataaagctc gcctgcaatc attttttctt
    15301 tttcggtttt gaattcagtc ataatctgct cctaattctt gtattttttt gaaaacaacc
    15361 gctccgtctt cttgaataaa cgtataaggc tccgctaaat aaacaggcgt ttgattgatt
    15421 actaagattt tggctgacgg ctggcgaaac tgtaccagat cacaaaacgg atgaacttga
    15481 aaactcgttc caacaatgac gatcagctct gcttggctga cggcataagc cgcctgctcc
    15541 atgactccat cttgaaaccc ttcaccatat aacacgatgt ctgggcgtat ttgtcctccg
    15601 catgcttgat gtttgtcgct gtgaagatat tctttccagt ctaccgtttg ttgacatttt
    15661 cgacaatgac attgatacag actcccatga aaattgacga gttgcgggct tttagccttt
    15721 gcgtgcaaac cgtcgatgtt ttgggaaaca acccaaacat ttttttcttt cgctagatgt
    15781 gctatttcca aatgaatgat attgggtttt gcttcaggat gataaatctt tttgacaaat
    15841 tgatagaatt tatccggttc attcaccatt gcttgatgac tcagcaagta ttccggctgc
    15901 tccatcccgt ggtagattcc tgacaaagat cgatagtctg gcactccaga aggtgtggat
    15961 acccctgcac cggtcaaaaa tgtaatttgc tgataagcta atatctcttt tgctgcttcg
    16021 tctactgtta attgtttcat gttttgtcac ctcactttcc attatagccc atactcgaac
    16081 aaatttattg ttgaaaagtc agaaaaatgg gaataaaaaa gtgttatggg catttgagca
    16141 atttatcaca atgttcactg acaaaagaat gaaaacgtgt tacaatactg ctgtataaaa
    16201 gtgaggtgaa tcgatatgtt accattcttt atttattggg gcgttattct ggcttgtatc
    16261 gcctggttag cgttaagcgt ttatttctct gttttttatc ttgtacgcaa agaaaatgga
    16321 aatctttggg cttttgcttt attcaacgtg attgccgcaa ttgttttagc cattacatta
    16381 gccgtatatc gaacatgggg ctggggaatc acccaatact caagtttgat ttatctaata
    16441 ttagccattt atggcgtcgt tgttcttttg caagcgatcc taggacgtga gccaaagaaa
    16501 gcggcagctt aaatgatcga gatggaactg gacacaggaa attttctgtt ctagttcttt
    16561 ttttattgta ttacatacat ttttgtgtat aattatacta tcgtttgcaa tggatagatg
    16621 attcacattt tgattgtttt ttcggtaaaa gtaaagattt ctatatttat cagtattttt
    16681 tcaaaaacca gcagttatag attgacaaag cctctcgagt atcgtaaact ttttttgtat
    16741 aaataactga atacgagatg cctcaatcaa tgaggtagag gtcgcgagaa tcattaaccc
    16801 tgtggagtga agcaaacatg gagaagcagg aatagggagg atcgccgaaa tgtgcacttt
    16861 tttgcttgga gtgtatgttg ggacgcaagt taagagcttg cggactgtct tagcagtgat
    16921 gctaagttgc gctatgtttt gtgagaggtt tatcacctta tggaatttta gcggcctttt
    16981 tatatctata aatcggtcgc tttttatttt ttcagataaa gctttaccgc atttcatcta
    17041 gaccgctcgt gtatcatata atcagaaagg gagaaaaaaa tgaaaaaaaa tatggtttca
    17101 gttgccgtac tatttgcttt tgtcttctca ctattcagtg tgggatctct ggcaaatgca
    17161 gatgaaaaaa caccgagcga tgagtttcgc gtaggtatgg aggctgggta tgcacccttc
    17221 aactggtctc aacaaacaga tgagaataat gccttgccaa ttcaaggcca aaatagttac
    17281 gccggcggtt atgatgttca aatcgctaaa aaagtagcag atggtttagg gaaaaaatta
    17341 gtcatcgtcc aaacgaaatg ggatggtctg gctcctgccc ttcaatcagg caagatcgac
    17401 gcgatcatcg ccggaatgag ccctactgct gaacgacgaa aagaaattga ttttaccgat
    17461 ccttattacg aatcacaatt agtagtagta gttcaaaaag atagcaaata tgcaaaagca
    17521 aaaagtttag cagatctttc tggagcaaag atcactgctc agttaaatac attccactat
    17581 actgtgatcg atcagatacc agatgtgcag aaacaacaag caatggataa tttctcagca
    17641 atgagaacag ctttagcttc tggaatgatc gatggttatg tcagcgaacg tccggaaggt
    17701 gtaacggcaa ctagtgtgaa caaagacttg gaaatgcttg aattcagcgg tgcagatggc
    17761 ttccagacaa acccggaaga tgttcagatt tctgttggta tgcgtaaagg cgacccggat
    17821 atccaaaaag taaaccagat tctttctggc atctctaacg atgaacgaac caaaattatg
    17881 gaccaagcag tcaaagatca gcctgctgca actgatagtg aagaaaaacc tggcatcatt
    17941 tctgatttca ctacgatttg gaaacaatac ggcaatatgt tcttacgagg tgctggactt
    18001 accttgttca tcgcattgat cgggacagtt gtcggtacta cacttggatt actgattggt
    18061 gtcttccgtt cggtacctga atcaggaaat gcactgactc gcttcttcca aaaaatcgga
    18121 aatgcacttc tttctatcta tgtcgaagta ttccgcggaa caccgatgat ggtacaagca
    18181 atggtcatct tctacggtct ggcactcgct tttggcattt cattgaaccg aacgattgcc
    18241 gctttgttta ttgtctctct caatactgga gcttacatga cagagatcgt tcgtgggggg
    18301 atttttgcag tagatgaagg gcagttcgaa gctgcgcaag ccattggtat gacccatggc
    18361 caaacgatga gaaaagttgt tattccacaa gttttacgga atatcttgcc agcaacagga
    18421 aatgagtttg ttatcaatat caaagataca gcagttttaa gtgtaatcgg cgtagctgat
    18481 ttgttcttcc aaggaaactc tgcttccggt gcgaatttcc aattcttcca aacatttacg
    18541 atcgtcggga tcatctactt agtcatgacc tttacgatca ccagaatcct gcgggcggta
    18601 gaaaagaaaa tcgatggtcc ttcagcttat accaagcttg aagaaatcga caattcaaat
    18661 ttgcaggaat aaggaggaag aatcatgaat gaaaaaatta ttgaaatcaa acatctaaga
    18721 aaaagcttcg gtgaaaatga agtattgaaa gatatcagcg taacagtcaa taaaggtgaa
    18781 gttgtgacga tcatcggttc ttccggttct ggtaaatcta ctttcttgcg ctgtatcaat
    18841 ttactggaaa aaccaacagg cggcgagatc atttataatg gagaaaatgt attagctcct
    18901 aaatataatt tacctaaata tcgaacgaat ctaggtatgg ttttccaatc cttcaacctg
    18961 ttcaacaata tgaatgtctt ggaaaactgt atgtctggtc aaacaactgt cctgaaacga
    19021 gataaagaaa ctgccaaaaa agtagcaatc gaaaatctgg aaaaagttgg tatggatcgt
    19081 tatatcgaag ccaaaccagc acaattatct ggtggacaga aacagcgtgt cgcaattgct
    19141 cgggcattat caatgaatcc agatgtattg ctattcgacg aacctacttc ggcgttagac
    19201 cctgaaatgg ttggcgaagt gcttaatacg atcaaagact tagcacatac tggcttgaca
    19261 atgcttatcg tgacgcatga gatggaattt gcaaaagatg tatctgaccg tgtcattttt
    19321 atggataaag gtgtgattgc agaagaaggt acaccagaag atatctttgt ccatccgaaa
    19381 gaagaacgta caaaagaatt cctttcacgt attttaaatg cttaggatca atagctgatt
    19441 gggacaaaga gctgcggtgt ttaccgcagt tcttttttat gaattactca taaaaggtaa
    19501 atttctgaaa attggctctt tgtcaataag gactgatgag ttgtg
//
LOCUS       DAFLWQ010000049        19457 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.050, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000049 DAFLWQ010000000
VERSION     DAFLWQ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.050"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            133..3660
                     /locus_tag="L1V16_001785"
     CDS             133..3660
                     /locus_tag="L1V16_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBN1276127.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="L1V16_001786"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="L1V16_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBN1276128.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="L1V16_001787"
     CDS             7448..7789
                     /locus_tag="L1V16_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1276129.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="L1V16_001788"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="L1V16_001788"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBN1276130.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="L1V16_001789"
     CDS             9146..11566
                     /locus_tag="L1V16_001789"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBN1276131.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="L1V16_001790"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="L1V16_001790"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBN1276132.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="L1V16_001791"
     CDS             13000..13737
                     /locus_tag="L1V16_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBN1276133.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="L1V16_001792"
     CDS             13751..14566
                     /locus_tag="L1V16_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBN1276134.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="L1V16_001793"
     CDS             14579..15226
                     /locus_tag="L1V16_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBN1276135.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="L1V16_001794"
     CDS             15242..15898
                     /locus_tag="L1V16_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBN1276136.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="L1V16_001795"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="L1V16_001795"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBN1276137.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="L1V16_001796"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="L1V16_001796"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBN1276138.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="L1V16_001797"
     CDS             18240..18758
                     /locus_tag="L1V16_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBN1276139.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /locus_tag="L1V16_001798"
     CDS             18865..19365
                     /locus_tag="L1V16_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBN1276140.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
BASE COUNT         6541 a         3341 c         4178 g         5397 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagc
//
LOCUS       DAFLWQ010000050        19173 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.051, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000050 DAFLWQ010000000
VERSION     DAFLWQ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.051"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(56..1624)
                     /locus_tag="L1V16_001799"
     CDS             complement(56..1624)
                     /locus_tag="L1V16_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBN1276141.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(1628..2038)
                     /locus_tag="L1V16_001800"
     CDS             complement(1628..2038)
                     /locus_tag="L1V16_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBN1276142.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(2035..2958)
                     /locus_tag="L1V16_001801"
     CDS             complement(2035..2958)
                     /locus_tag="L1V16_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HBN1276143.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(2955..3833)
                     /locus_tag="L1V16_001802"
     CDS             complement(2955..3833)
                     /locus_tag="L1V16_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HBN1276144.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(3820..5157)
                     /locus_tag="L1V16_001803"
     CDS             complement(3820..5157)
                     /locus_tag="L1V16_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBN1276145.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(5160..6263)
                     /locus_tag="L1V16_001804"
     CDS             complement(5160..6263)
                     /locus_tag="L1V16_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBN1276146.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(6337..7845)
                     /locus_tag="L1V16_001805"
     CDS             complement(6337..7845)
                     /locus_tag="L1V16_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBN1276147.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(7811..8503)
                     /locus_tag="L1V16_001806"
     CDS             complement(7811..8503)
                     /locus_tag="L1V16_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBN1276148.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(8525..9499)
                     /locus_tag="L1V16_001807"
     CDS             complement(8525..9499)
                     /locus_tag="L1V16_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1276149.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            9799..10671
                     /locus_tag="L1V16_001808"
     CDS             9799..10671
                     /locus_tag="L1V16_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1276150.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(11253..13451)
                     /locus_tag="L1V16_001809"
     CDS             complement(11253..13451)
                     /locus_tag="L1V16_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1276151.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLFSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            13683..14675
                     /locus_tag="L1V16_001810"
     CDS             13683..14675
                     /locus_tag="L1V16_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1276152.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNLAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            14735..16156
                     /locus_tag="L1V16_001811"
     CDS             14735..16156
                     /locus_tag="L1V16_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBN1276153.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            16149..17648
                     /locus_tag="L1V16_001812"
     CDS             16149..17648
                     /locus_tag="L1V16_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBN1276154.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            17687..19081
                     /gene="uxaC"
                     /locus_tag="L1V16_001813"
     CDS             17687..19081
                     /gene="uxaC"
                     /locus_tag="L1V16_001813"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBN1276155.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYLTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
BASE COUNT         5776 a         3902 c         3387 g         6108 t
ORIGIN      
        1 aaattcacta actagtgaaa ataagttagt gaacctcatt tattaaagaa ttaaattaca
       61 gatgatcttt tccatcatac ttgaaaaact caaaatcagc ataacttcct ctttttttat
      121 ttagatcatg cactgctatc ccgataaaat ttccagtaaa ccctcctgag agtatacaca
      181 tgtttttttg cggacctact ttcttccatt cttcagttga tacgtctttc aaatgaaact
      241 gtgctgtctc tttctttaca gtgactttca aaaaagtctt cttttctgtg agtggaatcg
      301 tccaatcttc tatttgtgct actccgtttt ctgattctat catacgtagg cattttccct
      361 tgtcctcatt ccaagtaaca taacaataaa tataattgga ttcatttaag tacagtacca
      421 gtccagccat ctgattaaaa ttattaggca tgtattcaaa tgctgtctcc gcatcaaaag
      481 taaaatccgt ttgccgaata gctaacaaat gatgttcgaa ggtagattga agagattcac
      541 cggaaatcag acgtaaaaaa cctggtctac attttgtatc acaccaatca gcatttggca
      601 aaatgcgtct ggcattccag ttcttcttta gctctccttc aaatgtatcc ataaactgat
      661 gatctttttc ttgttgtacc tcttcatttg tctcaatcat tatttcttcc atcggagttg
      721 tctggctatc tttaagtctt aaccaatcgt cggacgtcca atacacttct tgaatagcgg
      781 tttctcttcc caaaatagcc gcaccgttta atggtctggt acaaagatat gtcatgtacc
      841 atcttcctga cggggtttgt actaagctcc catgtcctgt acattgcaat gtagaagcag
      901 gtttgtcact agctgtcagc ataggaaaac caggatcaag ctcgtaagga ccagtaatat
      961 tctttgctcg gcaaactgta actgaatgtc ctcttcctgt accgccttct gccgtcatca
     1021 aataataata cccgttacga aaatacaaat gtggtgcctc cgttttcgct aattctgtac
     1081 ctgcaaatat tttatagatg ggaccatcaa gcttcttctt ctctgcatca tattcttgta
     1141 atacgatacc gctggattta ttcggtgtgt ccagacgata atcccatagt tcattgacaa
     1201 gccatttttt tcccgtttca agatcatgga acaaagaagg atcaaagccg ttactattta
     1261 aataaattgg ttcggaccaa ggacctgtga tctcagatgc agtgatcaaa taattgtgga
     1321 catctttaaa cggacggcct gcacttttga catctgtgta aacaagataa aacaatccat
     1381 cagcataact gatttgtggc gcccatatac ttccatttgt aggatttcct tgcaaagata
     1441 cttgagtggt caaaatatcc gttgtatgtg accagttgac taaatttttc gactcatata
     1501 ctcggattcc tggaagccat tcaaaagagg agacaataat gtaataccgc tctttcactc
     1561 ttaatatatt aggatctgga ttgaatcctc ttaaaatagg atttttcact ttgatagtct
     1621 gcatgattca ggctcctttt ctcattctta ctcgatataa actgaatgcc ccagctgcga
     1681 aataaaaaaa tgcaaaagga aacgcaataa actgagtgcc aatcaacaat atgaatcctg
     1741 ttataaaata caaaccagtg gcagttgtta agtattttcc tttagcagtc aaaaacaatg
     1801 ctactgctaa aaaagcaagt gaaataaaca acacaacggc aaacagacca gtcatgtcct
     1861 gtaataatcc aaatgtattt tctaaagaca aagttgaatg atctacagca agcgactgat
     1921 aacttttttt aaactctgac gcagacatat tacttaaagt aactgctaac ccgccaaaga
     1981 aaatcaaaga tagactgcca ccgaccattc ctagcaatag ttcccatttt cttttcattt
     2041 ctgaaccccc tgcttttcta aatgtatcca ttcaggtctt ttgatcgatg tttcataatt
     2101 gttattacgt tcagagaatt tgacagtctg ttcatttttc ttgtcatccc aattatccca
     2161 accagttggg tgaacatgcc cacctatctt acacgcttca aataagacat ttgcatacgg
     2221 acgccacggt cttcctaaat agacgtttct agtatcaggt tctgcagtca aggtacagct
     2281 ttcaaaacga taccctgttt tttgattttt cggcgtagat gctgctgtga tgtatccagg
     2341 atttttactg gctaagctat ggatatgaca ctgatgaaaa acggcatctg ccccaccaaa
     2401 tatgaaatcc accgttcctt caatccagca atattcatag gtctgacgac aatactcagg
     2461 attggcagaa gccggtgtac aaaaaggagt accatctttt tgcaaatcag gcaacggacc
     2521 cgtgcataag gtatcctgat aaccagatag tcgacagttt tttaaagata cgcgatctcc
     2581 tgaattgaat aaagcaacag cctgtcctac cttttctcct ggacctgctg tattttcgat
     2641 gtgaagattt tctaatacga cattcgatcc ttctaagaaa aaagtagcac ttcggaaagt
     2701 ccctaactgg ctaccgtcaa gatactcctg ttttgcaaaa cgattaccgg agataactac
     2761 tgttcctgct cccacaagtt taaaattgga taatctgctt tctatatatt catcatatct
     2821 tccttctttt actatcaaga cctttggatg gctatccggc aggcctgcca aataatcgat
     2881 tccttcttgg atagtttcaa aatccgtcgg ggtatctata gcattctttc caattatcag
     2941 tttgtctttc atcctcataa atgctccctt atgaattgtt tccaaatatt tctcatttct
     3001 tgtgtttcca tatgaccgcc tgttaaagaa aaagaagaaa agttttctgg actacccatt
     3061 gattgatact ttttgtccag cccttttctc agcttcagta cgccttcgtc caagcacatc
     3121 gtatcgtttt ttccaactaa gctaagacga gggcgcggag cgattttttc ttggattgct
     3181 aacgttgtat aagctgtcaa tagatttggc acatagtaat aaaacccatg atgatctagg
     3241 cggcgatgta gcaaaagtat ttcgatgtcc acctgtgccg ctagatcaat acaaactttg
     3301 acacgagaat ccaatgctgt cacccaccag cttaataagc ctcccataga aagaccaatc
     3361 gttgcgagcc gttgagtatc tgtgtcttcc cttgtctcca aataatcgat caagctgatc
     3421 acatcataaa tacgcattcc ccataacgtt tttcctgtta ataaaaattg tttgaacaac
     3481 tcgctttcag aaatacctcc gcgttcttca aatccccaag catcaatcga ccaaacagca
     3541 tatcccattc ctgtcagtac ttctgcaaaa gatggagaag ctaagtaagg agcaccatgg
     3601 atcaattcac ttttcccgac tgaaaaatct ccgccgtgag aatgcaggta aaggaccggc
     3661 ggaaacggtc cttctttttc tggataagca tagagggctg gtactgtttc caattcattt
     3721 aagtacaatt gatagtattc aagcataaaa ccgttttgtt tttctcggta taatcgtttt
     3781 ccactagggg tatgtctgct agatggagca cctaaaaaat cattcaactg cataagcaaa
     3841 gtttttacga acaaccagtt catccatatt ttctgattga tttgattgga atttctcaat
     3901 actgatttct ttagtatttt ctaatagaaa tgctggtccc tcgtgatttt caatcgacat
     3961 ctggttaaag gaaaccttac ccgcaaagcc aatataaaat ccttgtctgc tcatttcctc
     4021 tattcctgtc atcatagcag gaacaccggg aactgcatct tgggccatcg agacatcgat
     4081 attgtcaaat gtgatttctt gtatgaattg ttccgctaat ccataaataa aacctgcaga
     4141 agcatggaca ttccttgccg tgatattcga aaaatggatc cttctgaatg ctggtgtccg
     4201 ttcatctatc ggataagcct ttttttccca tacatacggt tctttccctc gcggaccaca
     4261 gaaataataa agattcagta taaatggaca catcacatta tccatgacta tattggatac
     4321 tcgaatatct tcaacgatcc cgcctcgacc tcgtctagat ttcaatcgta ttcctcgatc
     4381 agtttcttgg aagatacaat ttgaaatggt aatattacga atactaccac tcatttcact
     4441 tcctaatacg acaccgccat gtccatggac catcgtgcaa tttgtgatcg tgatattttc
     4501 gcaagcgatc ctttcgtacg tatcttcagt ccctgccttg attgcaatac agtcatctcc
     4561 cacgtcaata tggcaattac taatacgcac atttttgcat gattctggat caattccgtc
     4621 tgtatttggt gaatccgctg ggttcaagat cgtcaagtta tcaaacgttg cattactgca
     4681 aagaatcggg ttgatcgtcc aacttggtga ctggatcaat ttaatatctt tcacagtaat
     4741 tcgatgacag ttatggaaac tcatcaattt aggacgagga taagcgagat tatctggttc
     4801 atttctaaaa gtatgccacc atttttttcc atttccatct aatgtaccga aaccagtgac
     4861 agagatgttc tctacatttt gagcatagat acaggaagca taaacttttc gatggactcc
     4921 ttcccaacgt gaatgaacaa caggataatc ttttggatcg tcagagaatt tcagaaccgc
     4981 tcctgcgctt aaatgaagtt cgacattgct ttttaaaaat aaagctcctg ttagaaattc
     5041 acctgctgga acaactacgg tcccgcctcc gtcacttgct gcagcatcaa tggcttgttg
     5101 tattgcttca gtattcaatt catcaattga tgcgccaaat gtcaaaatat catacatatt
     5161 tataatgcct ccacttcaat caatgcttgc aagaatgcac caacgccttt ttgatcatta
     5221 caaataattg gttcactgat gtagtaagca tatgaaccat ctcgctgatc tgctccgcct
     5281 aaccctgcta cttgacagtt tttattcaag ttcagccagc cttcttttgt ttccagaaca
     5341 aattcatcaa gtaatccttg atgtgatttc ttcacttgtg gaagccattc ttctttgttc
     5401 agcagtccca aacgtattcc tttagccatt gcgtaaacaa acatactact gccggaagct
     5461 tccagataat ttcctttccg ttttgtttct gttgttactt gataccatgt cccgctgttt
     5521 tcttcttgat atggaagtaa tgcagccagt gtcttttcta gaatttcttt cagcaaagaa
     5581 caatctgttt cttcatgaag taattcatag gtatctgctg cagccatcaa ataccagcca
     5641 atcgatcggc tccaaaaatg atgggataga cctgtttttg gatcagccca tggttggacc
     5701 ttcttttcat cccatgcatg aatcagcaaa tttgtttttg gatcgaatag atgtttataa
     5761 ctgatttcaa actgtctcaa aacatcttgg taatcttttt cttcactaaa attctggata
     5821 aattcagcat aaaaaggaga acccatatat aagccatcca accaaatttg ataaggataa
     5881 atttctttat gccaaaaagc tccttcggat gtgcgtggat ggtttgccaa ctgctgggaa
     5941 aggagttctg ctgctttttt atatttttct tcgcctgttt ctttgtacaa taaaaagaaa
     6001 agctttcctg tatttacatg gtcgatattg tattcttcaa cgctgtagcc acggatcgtt
     6061 ccatcttctt gcacgaaata gtcgatattg tcttttatga aatcaaaata aattttttct
     6121 tgggttcgtt cccaaagtaa ttggaaccct ttaagtacga cgccatagtc ataagaccat
     6181 tttcctttat accacttttc ttcatataag cgaggtgttc tttccatgat actttttgct
     6241 aatttctttg accagttttc cattatttgc tctcctttaa aaattaaaat aggatttggg
     6301 acaaatacca agaagtattt gtcccaatcg tctatattac tgtgccgctg ctttgtatgc
     6361 ttcctcgtac tcttgtgtga ttcgatcgcc tccttgtgct ttccagtctt ctacagcttt
     6421 tttgaatcca tcttcgtcaa gctgtcccat gatgtattgc accgtagcat caatgacgat
     6481 tttttcaatt tctgatccta cttcattgtt cgtcggtgaa tccaatggca cagaaggatc
     6541 cattacagca aattcttcat tttctttgat caattgatta gagaattctt tttcagggtc
     6601 tgtatctttg aaagagaacg tcacttcact aggacgagag cttgataacg gttgcacctc
     6661 ttgttgccaa agatccatat cgataaattc gatagaacca tcatcattca attcataatg
     6721 cgttccttcg ataccgccag tcatcaattt atacacatct tcttctaaaa gatcatcaac
     6781 aaattgaagt aatttcttca attgtgcttc gtcttttact tgagatttgg gaaatgctag
     6841 caagccgcca ataccatttc cttctgacca aacatgataa ccgccgcctt caccatctga
     6901 gatcttgttt acaggcacta attccatatc atcttgaata ccttgaccca tcgtcttcag
     6961 attcttgata tccaccattc cagtgtagat tccagttctt ccttgtgcaa attgttcttg
     7021 ctgatcagtc ttttgggtaa ctgcaaagtc ttgtgccaaa tagccattct caaatagatc
     7081 tcttgaaaaa ttcaaagctt tcatatactc ttctgtatca aattctggag tgaatttgcc
     7141 attatcgtct acagcccagc catttggtgc tccaaaataa gaagtgaaaa gtttaaagct
     7201 ggtataacga atatcactag gcgcacgatc gccaaaacca actgtgtcgt ccacaccatt
     7261 tccatcagga tcgttttctg taaattgttt agctacttca taaagctcat ccatggtagt
     7321 tggaacatct agtcctagat tatccaacca gtcttttcga atgactaagc cagcacgagc
     7381 gtagtctttt tgtatcggta cgccgtacaa ggcaccgtcg atactcgcag cttcgattct
     7441 atcttcagaa atttgactta aatttttata gtcttttaaa tattctgata catcccagaa
     7501 tacgcctgat tttaacgcat tgcggacaga agagtttttc aacatcgcaa tttgaagtgt
     7561 aacgatatct cctagttcat cagaagccaa tgcagttgtt aatctttctt cttttgaagc
     7621 atcaggaatc cagttgaatg tcagttccgt atcggttttt tcttcgatca agttcacaat
     7681 cgtgtctgta ggcggtgaag catgatgcaa aatatttaac caagtgattt tagcttttcc
     7741 atcttctgtc tctgaagaac tgttacttga actgctgccg catgcggcaa gtgctagaat
     7801 tcctgcaaaa ctaagaccta attttacgag cgttgctttt ttcataaatt ttctccttca
     7861 ctgttttaat aatatttttg ttttcttctg ttttttctgt atatgagttc ttccattcca
     7921 aatggcaaaa tatagaattt gctgtccacg tgactgcgga aaagaagaga ctgccaccga
     7981 taaaggttaa aacacctggc attgtttgga tgatcatcag ataaatccct accatactta
     8041 atatcaacac taatgagtaa tgaagatgtg agaatccgaa taaaaatgcc attttcattt
     8101 tgaaaaaata tcctttccaa tcataatgag ccatgattgg gaaaatatag agtgctgaga
     8161 gcacatatat gaacgcagca atatacaaag cgatcctaag ataccaattg tgtatgaaag
     8221 aaagatccac aagtaaaaca atcccgatgg cgccatatat ccagctcatc agcaaggttt
     8281 cacgatagtt ttctttaaaa tatgtgaagt acgttttcgt caaaggaaac gtttcttttg
     8341 agcgcagcca ttttctaatc actgcaacca tcgcatacga tgcaggaccg aaagtaaaaa
     8401 ctcccaaacc tgcgatgact aaaccgcccc acagaaaatt caaataaacc aactgtaaaa
     8461 tacgatttag ccttccgttt attttatcta atgactgcag catatctttc cctctctttc
     8521 tatcttagta aacgccgtct tctcctagct ttttggcaat cttattagct aaaattacca
     8581 taaacaatcc tacgacccct ttaaacaatc ccattgctgt actgaaactt aactgtccat
     8641 tcttcaatcc agctgtataa atataggtgt cgaaaatttc tgcaacgctt cgattcaatg
     8701 aattcaataa caagtacata tgctcgaacc ctaagtctaa tgtctgaccg atttttagaa
     8761 tcagcaaggt aatgattact ggacgaattg ccggcaatgt aacatgccat gttttgcgta
     8821 agcgtcctgc tccatccatt tctgcagctt catacaactg tgtatcgact gcagttatcg
     8881 ctgaaaggta gatgatcgta gaccagccca actctttcca gatcacttgt ccgatatata
     8941 ctgtgcgtgt ccattcaggg gatgttagaa aactgatttt ttcaaatccc attgttgcaa
     9001 ggaattcatt caatacccct ccgtcaacat tcaaaaatac ataagtaatc gaaacaatga
     9061 ttacccaaga catgaagtga gggatgtaaa tgatcgtttg aatcccgttt ttcaatcgtt
     9121 tgttcgttac ttcatttaat agtaaagaca aaatgattgg catcggaaaa aacacgaaga
     9181 tatttaatcc gaacaagatc aacgtatttc ttaataatgt aaagaatgtc ggttctgtaa
     9241 acaaacgaat gaaatgtttg aaaccgaccc aaggacttcc cattattcct aaaaatggtt
     9301 gataatcttg aaaagcaata acgagtcccc ccataggaag atacctaaaa atcaagaaat
     9361 aaaggactcc cggcagaatc atcacatata aaaatttatt cgttttgatt cctgcaatta
     9421 ttttttttcg tcttctgagc ttttcttctt ttttcgatag cgtcagttga aatggttctt
     9481 gtttctttac actttccata agcccctcct tagttttgtg aatgtttgct gcttatgact
     9541 tcatgataga taactatctg aattacgtat ataatcattt ttaccgtaag taaaaacgct
     9601 tacatagcaa tgatttttgt gctatacaaa acgataaagt gtattttttc acaaataaac
     9661 tacgcatagc aaaccttcta tttttttcta tctgacactt agcataggaa atgattatat
     9721 acgtaatctt tcaccgatga taaattgaac atatagaaac agaaacattt aatttatttt
     9781 gaggaggagc ctatctatat gaaaaagaaa gtctctatag gagaaagaag ttttacactt
     9841 ttcaacaata cgtttctaat tttgctagct ttgatctgta tcgttccttt tttaaatatc
     9901 atcgctacat cttttgcttc tacacaagaa gtcgtcgcga aaaagtttat cctttttcct
     9961 actacctttt ctttagacgc gtatcgctac attctttcta cgccgaccat ttttagagca
    10021 cttgctgttt cgattggtgt tacaggtgtc ggaacgatcg tcagtatgtg tgcaacttca
    10081 ctgatggcct acggtctttc cagaaagtat ttgtttggtc gaggtttcgt caactttctt
    10141 gttgtatttt ctatgttgtt cagcgggggg atgattccaa cgttcttagt tgttcgttct
    10201 ctagggctgg tcaattctta ctgggccatg atcctgcctg tggctgttaa tgcaatgaat
    10261 atgatcatta tgagaaactt tttccaagcc ttgccggata gtttggaaga atcagcaaaa
    10321 atggatggtt gcacagattt tggtgtattt ttcaaaatta tgctgccatt agctttaccg
    10381 tctattgcta ctatctcgct tttttatgct gttacttact ggaacactta tatgactgct
    10441 attttgtata tcaacgattc atctaaatgg ccgatacaga ttcttttacg ccaaatcgtc
    10501 attgtatcaa gtgggatgca agcagaaagt agtgccgttg atgtgattcc accagcacaa
    10561 acagttaaaa tggctgttat cgttattgca acagtgccta tgctgattgt ttatcctttt
    10621 gttcagaaat attttgtcaa aggagcactc gtaggttctg tcaaagggtg attatgtact
    10681 gaacgcaaaa tggtagttgt gtcagaagtg gtcagcttca agaaataaga aggcatttac
    10741 gaaaattgct tcttaaattt ttgtgaaatt tcggcttatt tttcgaagaa tctactcctg
    10801 gaacaccgtg tatcagaggt tgtgaaagag acgttcagcc ttgagcgatg ataaaaactc
    10861 tcacaaacat tgcgacgagt aacccacagg agcaataaga agcgattttg aaaaatagct
    10921 tcccatattt cacaaaatta tgccttattg tcgatagcct gtctcttgaa cgccatttat
    10981 tcgtaaaaaa gaactgtgac aagacttttg tcacagttct ttttgcgtgc ttagccttga
    11041 aatttaacta tccataaata caaatactag ggttattcta acttctttta ttgcttgaat
    11101 cagtccacaa gaaaaacagc ctcttgatta aacggcgttt atcttgttga ttctgcggca
    11161 ataaaatcag ccagcagcaa aacatgaagt gctgtttttt gctgtcctct tttattgctt
    11221 gaatcagatc acaagaaaaa cagcctcttg attcacaaat atttttttcg atattctccc
    11281 ggcgtaatcg attccttctt tttaaagaaa cgaataaaat tttgcggatt tcgatattgc
    11341 aatctttctg caatctcttt tacggagagg ttagtctctt tcaaccattt ttttgctacc
    11401 tctaaacgat gattttgaac aaaatcacca aatttttctc ctgtttcctt tttaaataca
    11461 ttacttaaat agttagggtt ataatgcaac ctatcagcga tcacatctaa agacagatca
    11521 cgatcatatt ctgtgtagac gatatgcata atattctccg acaaattttt aaattcatga
    11581 tcagtgattg cttgagagca ttctgtgatt ggcagaacta attgttctaa aacaagtttt
    11641 tctagttctt tgggatgata attgttcagt gcttttacat aaatttgttt catgttatca
    11701 aagttttttg aatctactcc caataactgt cctaattgaa cgagttcatt gatcaagcgg
    11761 accgaaacta cttcccgact caaaggattt ttattttgtg caaacaatgc atcaatcaat
    11821 tcatgtacta aattcttcac ttcctgattt ccagaacgaa tggcttcaaa caatcgattt
    11881 tgttcttcta tcggatatct aataagtgtt ttttcatgag cagcaggaac gatttcctga
    11941 taaaaaataa ttgaacttgg accagtattt acacgataat acagggcttc ttttgcccga
    12001 tcaaccgatt gcttgctttc attcagcgtt tcgaaccggt tactgatgcc tatactgata
    12061 gttaaattca agtattcttt tacacgtttt tgaatgagtc ggcaatactc catgactttt
    12121 ttgcttgctt ctgcatcatc tttatccatt cgataaatag tggcttgcat ttcttcattc
    12181 aaaacgatcg gcagcattcg attttccttt ggcacaattt ccgtgatcat gttgttgatc
    12241 gctaaaagta gcaaatcacg ctccccaccg tgactatctt ctaacagatc gatttgaacc
    12301 aaagctgtat aatagcagtc attttgagaa ctataaccaa attgctgcaa ccgctgatct
    12361 agttctcgcc tttctactcg atttctaaat aaactaagta caaatagcgt ttccagctgt
    12421 ggcttttggg taactaagtg tgcacttaac gcttcttttt ctcctatgat ccgactgact
    12481 gattgagcga ccaaatctag ttctttccca ctgaatcctt ttgatttaag attcagacgt
    12541 tcctgtattt gagaaatcgg acgggcaaat ctgtccgaaa ataagtagga aaaaagacca
    12601 atgagtccta ccagtgttaa agacactgca actagcccga ttctcagatt gcggatcatt
    12661 gcgccaattg cactagagtc aacttctaat ctgtaaatcc aattattata atctgatttc
    12721 agtactatat acgttttatc tttttctctt atcactttca gctgattgta atctagatcc
    12781 acgtccgtta atacagttgg ttgctcttta ttttttactg tctgagtagt aaaaaggttg
    12841 ccaacttcgt tttcaataga aagtatgtct tctccacttt caccaacaac ttgttctatt
    12901 gtatgtttct ctatcgtagc aattcccaat gcatattttt ctttttcaaa cattggcaaa
    12961 gaaatcacca tttcgattcc tttgtttttc ttttgccaaa ataaattatt tttgttattt
    13021 atgtacttct gttgatactt ttcaacttcc tcttcggtca gttgactcaa cgatccattg
    13081 attactcccc atttaccagc caaactgact aaatcataat tattatcatc cataacaatc
    13141 gtttctataa aatttagttc tttcctgatt tcagaataag tggagtaatc tgtatatgtc
    13201 agcggatgct tgaatatgtc cgagaaattt ttggtcgaac catacgtaga aaacgaatat
    13261 tcaatcgttc taattttcca ttcaacgtta gttttaactt gcctgagcaa attctttttg
    13321 tctgttaaat aactcgattc gatcgattca taggtattct ggtaaatgaa taaactaaat
    13381 cctatgacaa gtacggctcc taataaaaac atcggtaaaa atattttata aaatactgta
    13441 cttttcttca ttttcttcct ctcctccttt taaaataaaa ggctttcatt tttctgtaaa
    13501 attgatactc atctaattaa atgagcattc cccgctttca agaatagcat aattaaaaat
    13561 aaaaatccaa gtaattttta acgtgtgcaa tcttttcata tcaaagatct attgacttat
    13621 cgtagttatc gtaatatgat gaatgcgtta acaaaaagtg aaaaagtaag gaaaatgatg
    13681 gaatggtaac gatcaaagat atcgctaaag cagctggcgt ttctcatacg acagtttctc
    13741 gtgctttgaa taacagcagt ttaataaaaa atgaaacaaa acaaaaaata cgacaactag
    13801 ctaaggaaat gaattattcg ccaaactata gtgcaaaagg tttagtgaat caaaaaaaat
    13861 atctaatcgg actatttttc tcaagtttgc ataaaggaac ttcatcaaat ttcctagcag
    13921 attccattgc aggcatccat tcagtattag acacaaatta cagtttatct gttgaaagta
    13981 tcgatgttgt tgatttaaca gaaatcaacc tgcaacgcta cgatggactg atcgttatga
    14041 gtcaaagtga tgatgatcag cctttcatcg actatctcaa agaaaaagaa tttcctttcg
    14101 ttgttgtcaa tcgtcacatc aatgatccag cggttatcaa cgtcactgcc gatgatgcgg
    14161 ccggtgttat gcaggcagta gattacggta ttggatgcgg acatacgaag atcgcttata
    14221 ttggcggaaa gaaaaatttt cgttcgacaa aagaacggga aaaaggggta ttgaaaagtc
    14281 taaaaaaagc gagcatccct gtcaatctag cctatttttt aacaggagat tacagcttag
    14341 aaagcggcct ccaaaacatg gaatacctat tatcactttc tgacctgcct actctggttt
    14401 tttgcggcaa cgacgacata gcgattggtg cattgagagc tgtacattta gctggcctcc
    14461 gtgttcccca gaacatttct ctgatcgggt tcgatgattc tccagtcgtc tcctatctca
    14521 atccgccgct taccaccgta cgtaagcctt tgaaagaaat gtgtcaagaa ggaacaaagc
    14581 ttttactaga tttgatcgaa ggcaggacga tcgaacaatc taaaattgag ctctccacct
    14641 tgttgatcct tcgtgagtcg atcaattact tgtaaactac aagtaatttt atataaaaat
    14701 gttaacgtgt gcataacaca gaaaggaagt ttatatgaaa aaactgacaa aagaattagt
    14761 gaaaaaaaac gaagcacctg taaaagttct tcagtttggt gaaggcaatt ttatgcgtgg
    14821 atttattgat tggcagattc agcagctgaa taaccaacaa ttgtttaaag gtaatgttgc
    14881 aatcattcaa cctttagaac aaggtcttgg aaatatgatg aaccagcaag ataatttata
    14941 tacggtcatt ttacaaggac tcagcaatgg cgaaatcgtt gatacttccg agattatcac
    15001 cgtagtagaa caaatgatca atccttatga tgaatgggat gcttatctat ctctagcaga
    15061 aaatgacgac ttggcctata tcgtctccaa tacaacagag gcaggaatcc aattcgtgga
    15121 gactgataat ttaacagata ctcccccaca gagcttcccg ggcaaactga cagccttttt
    15181 ataccgacgt ttcaaattaa acaaagctgg ctttaccatc attccttgcg aactgattga
    15241 cagaaacggc gaacgtctaa aagaaatcat tttacgctac gcagaaaaat gggatttaga
    15301 acctgctttt gttgagtggt tagaaaaaga aaatgttttc tgttgtagtt tagttgatcg
    15361 catcgtccca ggttatcctc gcgaagatgc aggtgttttc aatcaacggc ataactatga
    15421 agatcaattg atggtcaaag cagaaccatt catgctttgg gtgatcgaag ggcctaaaga
    15481 attggagaat caactaccat tcaaacaggc tggcttgaat gtcatcatca cagatgatat
    15541 gactccttat cgtgaacgta aggtgcattt gcttaatgga ccgcatacag cgatggtccc
    15601 tcttgctttg ttggcggaat tggaaactgt agaagaagta atgaaagatc ctttattctc
    15661 cgcatatgtt gatcagttat tcaatctaga attgattcct atgctttctt tacctaaaga
    15721 tgaattagcc atttatgctg accaaatcaa agaacgtttc ttgaatcctt ttgcccatca
    15781 caaattagaa gcgatttcat taaatagtgt ttcaaagttc agcacccgtc tgcttccagt
    15841 gttcaagaag tatatcgaag aacaaaatca ggtaccaccg ttaatcactg tttcactagc
    15901 tgcgctactt cttatgtatc gaggcgatca agtaaagcca catgatgatg aaaagacgat
    15961 aagcgaattt actgatgctt ggtctgataa tggaacagct attcctcgat tattgcaaaa
    16021 cgctgcgctt tggggagaag atttgtctca aataccgaat gtgacagata cagttcaaga
    16081 aatagctgca aagatcgatc aaaaaggtgt ccggtcagta ttacaagaaa tgaaaggaac
    16141 gatggtccat gcttgaaacc ctgcaaccaa caatgaaatt aaatcgacga gacagtgtgg
    16201 tcgtcgcatt aacccctatt ccaaaacaaa cacaactgac gattgatcag caaacgatca
    16261 ccactcttga agatatcccg caaggtcata agattgcatt gggtgatttg aaagctggag
    16321 acaacgtgat caaatatggc tatccaatcg gtcatgtgac gacagacgta actgccggtc
    16381 aatggctgca cactcataat gtaaaaacca atctttctgg tgaattggat tatcgatatg
    16441 aaaaagatgt ccatccaagt cattaccttt ttgagaaccg aacatttcaa ggttacttgc
    16501 gaaaaaatgg aaaagtaggg attcgtaatg atttgttttt agtacctacc gttgggtgtg
    16561 tgaatggcat tgctgaactg atcgtcaaac agttcaagga aaaacatcca gatctgggac
    16621 agtttgacca tattacgatt ttaaagcatc cttatggctg ttcgcagctt ggaaaagatc
    16681 atcaaaatac tcgagaaatt ttagcggacg cagtaaatca tcccaatgcc ggaggagttt
    16741 tagtatttgg attaggttgt gagaacaata cagttcctga attcaaaaaa attttaggtg
    16801 aatatgatga agaacgagtg aaatttctag tggctcaaga tgtttacgat gagatcgaac
    16861 aaggtgtggc tctattagaa gagcttttaa cagcggcgga aaatgaccag cgcatatcag
    16921 tcccgctctc taagttgaat gtcggtttga aatgcggcgg ttctgatggt ctatcgggaa
    16981 taactgctaa tcctttactt ggtgcatttt ctgactactt gattgctcaa ggaggcagca
    17041 cgatcttaac agaagtgcca gaaatgtttg gcgcagaaca agtattgatg gcacgagcgg
    17101 aaaatgaaga agtttttgac tcaatcgttg acttgatcaa tgacttcaaa cagtatttct
    17161 tgtcttacgg ggaaccagtt tacgaaaacc catctcctgg taataaagca ggtgggatca
    17221 ctacattaga agataagtct ttaggctgca cgcaaaaatc aggaagctct cctgtcgttg
    17281 atgtgctaca atatggcgaa aaaatcagaa aaccagggct tagtttattg caagctcccg
    17341 ggaatgatct tgtagctgcc tctgctcttg cttcatccga ttgccagttg gtcttgttta
    17401 ccacaggaag agggactccg tttggctcat atgtcccaac ggtcaaggta tctacgaata
    17461 caactctttt tgaacgcaaa ggtcattgga tggattttaa tgcaggcgtc ttattagaac
    17521 aaccaatgga agtaatctta gaatcgtttg ttcaaaaaat catcgctgta gctagtggag
    17581 aagaaacgaa aaatgaacaa aatgacgttc gagaaattgc catttttaaa aacggagtaa
    17641 cactttgatt ttcataaaac agtataaaaa gaaagaagga agatttatgt ttttatctga
    17701 tgatttttta ttaaaagacg attgggcgaa aaagctttac cattcctacg caaaaaacat
    17761 gcccattatt gattatcact gtcacttaga tccaaaagaa atttacgaaa acaacaattt
    17821 cagcaatctg acagaagctt ggttaggagg cgatcattac aaatggcgct tgatgcgagc
    17881 ttgcggcgtg cctgaagaaa aaatcacagg aaatgcttct gattttgaaa aatttttagc
    17941 ttggtgtcaa accgtaccaa aaattatcgg aaatccgctt tacagttggt cacatcttga
    18001 attgaagcgt ttcttcggta ttgacttgtt gataaatgaa gaaaatgcag agaaaatttg
    18061 gacacaagca aatgaaattt tggcagctcc tgattttcgc cgtcgggaaa tcgcaaaaaa
    18121 atcgaatgta gaagtgattt gtacaacaga tgatcccgca gacgacttgc actatcatca
    18181 gttgcttgct catgaagaac cagatttgaa ggttctacct tcattccgtc cagataaagc
    18241 actcaatatt gaaaaagaag gatttaatgc atgggtcaca ctactggaag aagcagctga
    18301 ccaaacgatc accacctatc aagaactgat agaagtctta gggcagcgga tagaatactt
    18361 ccatcaacat ggatgtcgtg tttccgacca cgctttagac atcttacgct ataaagaagc
    18421 ggatgaaaca gtattagaag agatttttca aaaagcacga gctaacaaac tattatcttc
    18481 agatgaaatc gatgcttatc ttacagaaac actgatacat ttgacccact tctatcattc
    18541 tcataattgg acgatgcagc tgcacatcca tgcttatcgt aactgtaata cacaaatgtt
    18601 ggaaaaatta gggcccgata ccggctatga tggaatgaat gatctttctt tgactattcc
    18661 tctgcaaaaa ttattgaacc gtgcagaaga aacggatcag ttgccaaaga cgatccttta
    18721 ttcattgaat ccgaatgact atcctgcgat tttagctttg atgggctgtt tccaaaaaga
    18781 acagaatgga aaactgcagt taggttctgg atggtggtac aacgatactc gagctggtat
    18841 gcgcgatcaa ttgacacaat ttgctgatgg tagtgctttg gggaattttg tcggcatgct
    18901 gacagattca agaagtttcc tgtcctacac tagacatgaa tatttccgtc gtgttctttg
    18961 tgaattttta ggcgaaatgg tcatgcgagg agaagcacct gaagatgaac aacttttagg
    19021 aagtctagtt caagcgatta gttatacaaa tgctaaaaat tactttggct tttttgccta
    19081 attgattaat agtaacagta acgaatcaaa aacaggatag tgaaataacg gaatccgttt
    19141 atccacgttt tagagaagaa gacggaccaa att
//
LOCUS       DAFLWQ010000051        18915 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.052, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000051 DAFLWQ010000000
VERSION     DAFLWQ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18915
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.052"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(27..602)
                     /locus_tag="L1V16_001814"
     CDS             complement(27..602)
                     /locus_tag="L1V16_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBN1276156.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(607..1581)
                     /locus_tag="L1V16_001815"
     CDS             complement(607..1581)
                     /locus_tag="L1V16_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HBN1276157.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(1605..1649)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1864..2832
                     /locus_tag="L1V16_001816"
     CDS             1864..2832
                     /locus_tag="L1V16_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1276158.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            2929..3222
                     /locus_tag="L1V16_001817"
     CDS             2929..3222
                     /locus_tag="L1V16_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBN1276159.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIVDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            3340..3576
                     /gene="secG"
                     /locus_tag="L1V16_001818"
     CDS             3340..3576
                     /gene="secG"
                     /locus_tag="L1V16_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBN1276160.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3679..4434
                     /locus_tag="L1V16_001819"
     CDS             3679..4434
                     /locus_tag="L1V16_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBN1276161.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            4437..6794
                     /gene="rnr"
                     /locus_tag="L1V16_001820"
     CDS             4437..6794
                     /gene="rnr"
                     /locus_tag="L1V16_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBN1276162.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            6816..7280
                     /gene="smpB"
                     /locus_tag="L1V16_001821"
     CDS             6816..7280
                     /gene="smpB"
                     /locus_tag="L1V16_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBN1276163.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            7582..8301
                     /gene="atpB"
                     /locus_tag="L1V16_001822"
     CDS             7582..8301
                     /gene="atpB"
                     /locus_tag="L1V16_001822"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBN1276164.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            8354..8569
                     /gene="atpE"
                     /locus_tag="L1V16_001823"
     CDS             8354..8569
                     /gene="atpE"
                     /locus_tag="L1V16_001823"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBN1276165.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            8660..9184
                     /gene="atpF"
                     /locus_tag="L1V16_001824"
     CDS             8660..9184
                     /gene="atpF"
                     /locus_tag="L1V16_001824"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBN1276166.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            9171..9713
                     /locus_tag="L1V16_001825"
     CDS             9171..9713
                     /locus_tag="L1V16_001825"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBN1276167.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9736..11292
                     /locus_tag="L1V16_001826"
     CDS             9736..11292
                     /locus_tag="L1V16_001826"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBN1276168.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            11306..12208
                     /locus_tag="L1V16_001827"
     CDS             11306..12208
                     /locus_tag="L1V16_001827"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBN1276169.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            12231..13637
                     /gene="atpD"
                     /locus_tag="L1V16_001828"
     CDS             12231..13637
                     /gene="atpD"
                     /locus_tag="L1V16_001828"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBN1276170.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            13651..14073
                     /locus_tag="L1V16_001829"
     CDS             13651..14073
                     /locus_tag="L1V16_001829"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBN1276171.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            14542..14772
                     /locus_tag="L1V16_001830"
     CDS             14542..14772
                     /locus_tag="L1V16_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HBN1276172.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            14869..16170
                     /gene="murA"
                     /locus_tag="L1V16_001831"
     CDS             14869..16170
                     /gene="murA"
                     /locus_tag="L1V16_001831"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBN1276173.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            16183..16359
                     /locus_tag="L1V16_001832"
     CDS             16183..16359
                     /locus_tag="L1V16_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBN1276174.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            16494..16790
                     /gene="yidD"
                     /locus_tag="L1V16_001833"
     CDS             16494..16790
                     /gene="yidD"
                     /locus_tag="L1V16_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBN1276175.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            16854..17321
                     /locus_tag="L1V16_001834"
     CDS             16854..17321
                     /locus_tag="L1V16_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1276176.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            17406..18290
                     /locus_tag="L1V16_001835"
     CDS             17406..18290
                     /locus_tag="L1V16_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1276177.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLIGAAANYLAVRQGEN"
     gene            18404..18640
                     /locus_tag="L1V16_001836"
     CDS             18404..18640
                     /locus_tag="L1V16_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HBN1276178.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            18728..18808
                     /locus_tag="L1V16_001837"
     tRNA            18728..18808
                     /locus_tag="L1V16_001837"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18762..18764,aa:Tyr,seq:gta)
     gene            18815..18886
                     /locus_tag="L1V16_001838"
     tRNA            18815..18886
                     /locus_tag="L1V16_001838"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18847..18849,aa:Gln,seq:ttg)
BASE COUNT         6281 a         3306 c         4097 g         5231 t
ORIGIN      
        1 tattttgcta atccagctct gtttattcag cctatttttc tttttgaata tatcaagcgt
       61 tgtggcaaca tagtgatgac taatgaaaca acgacgatag acaacaaacg atcaaggtag
      121 tctgtacctg cctgtaccaa gatcacactt gttgtctgac ttaaacctaa cccatgtaat
      181 agctgaacga tcatactgga tcctgaggag gtgatcccgc caaataactg aacggtaatg
      241 atcgaagaaa cgatcgttcc aggtaccgac aaaatcaaag cgagtaataa cagtttcaag
      301 ctgtttttat ctttgccgag atatcttggc aaaatcaatc cagcaagcaa gcctgtgaga
      361 atttggattg gcgaataata cagagaaaaa atatctgtag tcactccact taaaataccg
      421 ctggacaatc ctgtcagcat tccaggtaca ggcccaagca atgcaccagc aaaaatcgtt
      481 ccgatagaat cgagatagat tggcaaacga agccataaag caatcgttcc tccaatataa
      541 ttgatcccaa tacacaaagc catcactgta agtacgcgag ttgccatttt gtttttattc
      601 attttgttag cccatcttta acctttccaa atctttcata atcgtttctt cttgtgcatt
      661 taaaagaacg gttaaaaact ttcggaaaaa aagacgagta tctacttttg tcataatttt
      721 actgttagca ggtttctgcc aaaattcata acgatcaacc aatgtttgtc cacgacttat
      781 tccttgagtt tccacagcag tgaagctttt gaaaccttca cagatggcct cctcgataaa
      841 ataagcaaca gctaacggat cattgatgac acatcctaaa attctttctt gtttccagtg
      901 gaagtcaaaa taaaaacgag tgatcgcttt tagatactct ccctcttcag gattcatttg
      961 acagcagtat tcgaggatag tcggtgtcaa gacgatttct cttgtcacat ctaacccaac
     1021 catttctatc gtttgtttga gattctcgaa tacataagaa gctgcttcag gatcacacca
     1081 gtaattgtat tcagcaactg gcgaacagtt accatggctt ttgtaagttc cacccatcga
     1141 gacaaaacgt tccatatgtt tcccaatatt tgggttgact ttcaaagcag aagcgatatt
     1201 ggtcaaagga cccaaagcaa tgactgatgt atttgtcttt tctttgaaat aatcagccaa
     1261 aaaatcaacg gcatggagag gttctgcctg ttttctcaag atcatcggga aatttgtttc
     1321 ccctaaacca tccataccat gagtgtcttg tgcactgatg aaaggttgct tcaaaggttt
     1381 ttccattcct tgataaacag gaatgtctaa acgatcacag cgttccaggc atttcagcac
     1441 attctgcgta cctatatctg cagggacatt cccacaaact acggtaatag caactacttc
     1501 gatatcaggg gatttgacag ctaatgataa agctaaagtg tcgtcgatcc ctggatcgca
     1561 atcaataatt acttttcgca ttatttccaa tctcctttct ttagagatac ttagtttttt
     1621 attctgggaa gtttccgaac cagtccaaga cgagcgtctt gattataatg cacgaaatta
     1681 gtatactggc ttttattgcg aatgtaaatg ctctcttaca agtaaatcta ttgaggagaa
     1741 ctttaagtaa atgatacaat gaaaaagaaa tggaatttac gtgtgccgaa aataaagaat
     1801 cctatggatc ggtacattgg ataatagata gattatagtt tggcagaaag cggcgggtgt
     1861 acaatggtta ttttttattt cattcttatt ctgataatta tagggatcag ttaccatttt
     1921 ctttcttatt tttatgcaaa gaaattagta agagcgggag tacagagagg atatgactgg
     1981 tatgaagaca ctggtcatcg tttgatggac cctgctgcag tcacgtcagt agaaaaaaaa
     2041 cgacaaaaat tagaagaaga gtgtgaaagc ttttgggagc agggaacacc caaaacaatc
     2101 aaaagttatg acgggttgaa actagctggt cagatgttca tccatccaaa taagcagaat
     2161 aaatgggtca tttgcgtaca tgattaccga agcacaggga aaagagacat gtctcatata
     2221 ggtaaaagat atgcagagaa aggattcaac gttcttgtac ctgatttacg tgcgcacgga
     2281 gaaagtgaag gagaaatcat cggaatggga tggctagatc ggctagattt aattgcctgg
     2341 atccaactca tcttagatga acagccgaat gcgtccatta ttttacacgg cggatcaatg
     2401 ggagcttcta cgatcatgat ggcaagtggt gaaaaacttc catcagcggt caaaggattt
     2461 attttagaca gcggatatgt ttctgtttat gcagaattcc gatatatgtt aagtaaaatc
     2521 actgtctttc ctaaaaaaat ggtcatgaga tatgcgaatc attatgccca gaaatacgcc
     2581 ggttactcct taaagcaagc atcagctacg agacagcttg gcagcaatca tctgccttta
     2641 ttagtcatcc atggtgaaag agatcatttt gtccctacag aagcagcgta cacgattcaa
     2701 aatgctacgg caggggataa agcactgctg cttgttccgg aagcagaaca cttggaagca
     2761 tcgatgaaag atccgaaaac ctattggaca gtgatttttt catttattga acaaagaata
     2821 acgatgaatt aattttctct tcttttttgt aagtaattcg aggataaata attgtttata
     2881 gatcaggaga ctgctaaaat aaggtaggaa taaaaaaata tcagttattt gaggagtgcg
     2941 gcatatggaa atcaaagaag aaaaaatcgt cttgctttat tcaatgatga acaacaagag
     3001 atcggagaaa tgacatggtc agatgcgggc ccagacatca tgatcgttga ccatacattt
     3061 gtagatccag catatcgtgg tcaaaagtta gctgaaaagc tagtgtatac tggagtagaa
     3121 ttagcaagac gagacgggaa aaagatcatt cctttatgcc cttatgcaaa aaaagagttt
     3181 gaaaagaaac cagaatatca agacgtctta cgtcagtcat aagaataaca gctgaaagtt
     3241 ttgaactttc agctgttatt ccatttatat agagttgtca cggactttta tctatgataa
     3301 agttaaagag acgatatctt ttgggaagga ggctgcgata tgtataattt aattttggga
     3361 atcgtgatcg ttttatcgat tgttatggtc attgcgatta tgatgcagcc aagcaagcaa
     3421 aatagtgcag cgagtgcatt taccggcggt gcggatcaac tattcggcaa acaaaaagct
     3481 cgcggctttg aagctgtcat gcagcgatca actgcagtta tgggagctat ctggatgatc
     3541 ttattatttg tcctagcata tttatcttcg aagtagttga ataagcctct cgcaaaacgg
     3601 cgggcggctt tttttattgc aaagagaacg cttaagaaga agttatgaaa gaaactatgg
     3661 taaaatgagg cgaaagaggt gagacgagtg agacaattac caaaacccct ttatgcaaaa
     3721 catggaaagc gagcggtttt gctgcttcac gcttactcag gaagtccaaa cgatgttcga
     3781 atgctcgcac gatttttgga aaaagcagat tatacagttt atgcgccgct ttttaaagga
     3841 cacggaacaa tggagccata tgatatcttg caagaaaaag cagaaagctg gtgggcagac
     3901 actaaaaaag ccatccattt tttacagtct gagcagtttt ctgatattgc cgtattagga
     3961 ttatcaatgg gcggcatctt tgctgtacga gcactagaag aagaatcagt gattggcggc
     4021 ggttttttct gttcgccttt gtctcctgta aaaacaaacg tgcctgaaaa ctttgaaaaa
     4081 tacgtacgtc aagtgctgaa gacagcaggt aaatcagaga aagaaatcaa tgaaaaagca
     4141 gttgcttacc gctcgttagc tgaacaacaa ttaatggata tacaagatca ggcagcaatc
     4201 gtagaaagta ggttgtcaga tatccaacag ccgatatttt tagctcaagc tgggaaagat
     4261 gaaatgatcg accctaatgg cgtatttgaa actgcacgca agttgagccg tcagcgagtg
     4321 acacttcaat ggtatcctga aagtggtcat gtgattacag ttggtacagc aagacgcgaa
     4381 ttagaaaaag acgtcttgga atttttagaa aaattacctt ggaatgagga ataaatatga
     4441 caaaagaaac gataaaagag aaaattctct ttttcatgga aagcagtcgc aaacgcagtt
     4501 tttctatgga agaaatcgct gaaggtttag ggttccaaaa aagcgatgat tttaaattac
     4561 tagtacaaac gattgctcaa atggaaagag aacagagtat agttttcaat aaaaaaggaa
     4621 aagtgaaact tcctttaaaa ccaatcctga tcgaaggaac atttcgagca aatgaacgag
     4681 gatttggatt tgtaacgatt gatcccgaag aagatgacat ctatatccca aaagaagcga
     4741 ctggttttgc aatggatgga gacaccgtag caatcgatat catgaagcga gcaaatacag
     4801 atatggatcg cggagcagag gggaaagtag tcgagattcg agaccgggcg actactcagt
     4861 tagcagggga attcgttgct tattcagaag aagaaataca agaaacagat ctttacggcg
     4921 ttgttatccc gaaagataga aagctcaacc aatttaaagt atatgcagca gcagagggag
     4981 ttcgtccagt tgacggaagt attgtgctga tcgaactgac ccattaccct gaaaaagggt
     5041 atgcgactag tttagaaggg ataatcaagc aagtgattgg tcataagaat gaccctggca
     5101 tggatatcct ctcaattgtc gtggctaatg gtatccctac gaaatttcct gatgatgtat
     5161 tgtctgaagc agatgaagtt ccagatcaaa tcagcgaaaa ggatataact ggacgtagag
     5221 atttaagaaa tcagctcatt gttacgattg atggagaaga tgcaaaagat ctagatgatg
     5281 cagttacggt taaaaaatta gataacggta attattttct tggagtacac attgcagatg
     5341 tttcttacta tgtgacacaa ggcagtcaat tggacagaga agcatatgaa agagggacaa
     5401 gtgtatattt gactgatcga gtaattccga tgatcccgca acgtttatcg aatggtatct
     5461 gttcactgaa tccccatgtt ccaaggctga ccatgagttg cgaaatggag attgatccaa
     5521 atggacaagt agtctctcat gatattttcc caagtgtgat ccaaacaaca gaacggatga
     5581 cctacacagc tgtcaatcaa atcttagaag atcaagacga agaaacgatg caacgctatg
     5641 ctcagctcgt acctatgttc caagaaatgg gtgaattgca ccgaatcctt gaaacgatgc
     5701 gaatcaaacg tggcgcgatt tcttttgagg atcgcgaagc gaaaatcctt gttgatgctg
     5761 aaggacaccc aaatgacatc cagctaagaa gcagaggaat tggtgaacgc ttgatcgaat
     5821 ctttcatgct tgcggccaat gaaacggtag ctgaacatta taataaatta aatctgccgt
     5881 ttatttaccg aatccatgaa cagccaaaag aagaaaaaat gcagcgcttc tttgattttg
     5941 cttcagcttt gggcattctg gtccgaggaa cgaaaggaac gatcacacca aaagatttac
     6001 agcatgtgat cgaaggagta gaagacaaac cagaagctgc agttatcaat actatgttgc
     6061 taagaagcat gcaacaagca cgctattcag aagacaattt tgggcattat ggcttagcgg
     6121 cagattacta cacacacttt acatctccta ttcgacgcta tcccgatcta atcgtccatc
     6181 gtctgatccg ttcttacagt gaagataaaa gtgaaagcaa tcaaagttcg tgggctgcgg
     6241 aacttcctga aattgcagat catagttcta agatggaacg tcgtgcagta gaaacagaac
     6301 gtgaagtaga ttccatgaag aaagcagaat tcatgatgga caaagtggga gaagaattcg
     6361 atgggatcat cagctctgtt gtgaaattcg gcctgtttat cgaactgccg aatacagtag
     6421 agggattgat ccatatcaat gaattgaaac aggactactt ccattttgtt gaaaatcatt
     6481 tagctcttgt aggtgaaaga actggtctga cttttaaaat cggacagaaa gtgcgagtaa
     6541 aagtagtcaa agctgatcca gatgaacgag cagtagattt tgaacttgtt tccgcagaag
     6601 aggttacagc gttggaacgg ccaaaaacac gaaatggaaa atcaggaaaa cgcgaaggaa
     6661 aacaagcagg aaaacgccca gaaagaaatg gcaagaagaa caaacgatat agcgatagta
     6721 agcaaacgtt cggtaagaaa aaagggaaga agccatttta caaaggtgtt aaaaagaaga
     6781 aaaagaaaaa ataaaatgag ttggaggaaa cagctatgcc aaaaggcgag ggaaaattaa
     6841 ttgcacaaaa caagaaagct cgccatgatt attcgatcat cgacacgatg gaagcaggga
     6901 tggtcttgca aggaaccgag atcaagtcga tacgaaacag ccggatcaat ctaaaagatg
     6961 gatttattcg cgtccgcaac ggagaagctt tcttgcataa tgttcatatc agtccttatg
     7021 aacaaggaaa tatttttaat catgatccgt tgcgcacgag aaagttatta ttacacaaaa
     7081 aacaaatcat ccggcttgaa aatgaattga aaaatactgg aatcactgtt gttcctttaa
     7141 aagtctatat tcgtaacggc tatgccaagg tattgattgg tctggcgaaa gggaaaaaat
     7201 cttatgataa acgggaagat ttgaaacgaa aagatatcga tcgacaaatt gatcgaacat
     7261 taaaaaattt ctctagataa tttcattatc ctttttcgca tattcggtgc ttttgctttt
     7321 acttaatgat aaaatttgtt agcatttaat ctgataaaac atgattatca taggtttttt
     7381 cttagatcag gagcaccgtg tataaagaaa aattcgcttc gtttttgact gaaataaaaa
     7441 agtgtctaat tttcatgaaa atgttttgaa ttttctgttt catggtggta tgataccgtg
     7501 tggttagaaa ccgattggaa aaaaccagat acgcacatga attgatttta tgtgaatttc
     7561 ggggaaaaga ggtgaaatgg attggatgaa cgctcgctaa cgttccacat tggaccaatt
     7621 tggtttgatg gtacagtttg tataatggtg ttactgacct gtttgattgt tttcttctta
     7681 gcttactttt ttacaagaaa tcttaagttg aaaccaacag gcaaacaaaa tgcgatagaa
     7741 tgggtcattg attttagtcg aggaatcgta acagataatc tgcctagaaa agaattgagc
     7801 aatttccatt tgttggcatt tacattgttt ttatttgttt ttgttgcaaa caacatcggt
     7861 ttagtaacaa aaatcgtttt acctaacgaa acaacacttt ggaaaagccc gacagcagac
     7921 ccgtttgtta ctttaacttt ggcatttata atgatcttac ttactcactt attcggggtg
     7981 aaaaagttag gcttcaaagg atatttcgta aattcgttct tgaaacccta tagttttatg
     8041 tttccgatga aactgattga agaatttaca aacttattaa cacttgcttt acgtctttat
     8101 gggaatattt atgcggggga agttttgcta accttgattg caaaaatgat gacaagctta
     8161 ggctggttct cattaccatt agcaattcca ttagagatgg tctggatcgc gttctccttg
     8221 tttattggga gcatccaagc atttgtcttt gtcactttgt caatggttta tatgagccat
     8281 aagattgaag tagaagaata atactcggtt aaaaaacaaa ctactattta tctattttag
     8341 gaggaaaaca attatgaatt atatcgcagc agcaatcgca atcatgggag cagcaatcgg
     8401 agccggttat ggtaacggtc aagttatctc taaaacaatc gaatcaatgg ctcgccaacc
     8461 tgaaatgtct ggtcaattcc gtacaacaat gtttatcggg gtagctctag ttgaagctgt
     8521 tcctatctta ggggtagtta tcgccttgat tctagttttt gccgtttaat tgaatcagta
     8581 ttaaggcaga aacaacatcg tttgttactg cttttttaca tggaaactag aaatactcca
     8641 aagaaaggaa ggctcgccta tgctgaatca attggcaatt gcagaagttg gcaatgcgat
     8701 gttaggtaat atcatcgttg tcagcggctc atttttgata ctactggctc tcttgaagca
     8761 ctttgcttgg ggaccaatca gcgatatttt gaaaaaacgt gaagacaaga tcgccaatga
     8821 tttagattct gcagaacaat ctcgcatcaa ctcagcgaaa atggaacaag aacgcgaaca
     8881 acaattgtta gcctctcgtt ctgatgcagc tgatatcatc aaaaatgcga aagaaagtgg
     8941 agaattaagc cgccaaaata ttttgaagga tgctcaagaa gaagcagctc gtctaaaaag
     9001 caaagcccaa gctgatatca ctgtagaacg tgattcagcg ctgaactctg taaaagacga
     9061 cgttgcagaa ctctctcttc aaatcgcgga aaaaatcttg aacaaagaat tatctccaga
     9121 aatgcatgaa tcattaatca atcaatacat tgaaggtcta ggttcttcaa atgaaactag
     9181 ataaatatac agtaggaaga cgttacggga aagctttatt tgaactggcg atcgattcaa
     9241 atcaagcaga agaaatctat caagatctcg taagtttacg tcaaatctat gaacaagtac
     9301 ctggattagg gaatatgtta agtgatgttc gtctagaacc tcatgaaaaa cgagaaatca
     9361 tggacaagct tgtcagcggt tatgatggga tcgttaaaaa ctttttagaa gttgtttatg
     9421 agtataaccg aatggatgac cttttgttca tgatcgaaga atatgaacgt cgatatgatg
     9481 aacatcaagg gttactattg ggaagtgtca caacagcagt cccactttca gacgaacaac
     9541 gaatacaatt agaaaagaat gttgcaaaaa caatggacta tcaatcagtt gaattaaaac
     9601 aaatcgttga ttcttctatt attggtggcg cgattgttga agccaaccat cgagtaatcg
     9661 acggaagcat tcgcacgcaa ttagaaaaaa tgcgtaatca attaaacaga tagtacaaag
     9721 aggtaggtga atcgaatggc catcaaagca gaagaaatta gtgccttgat taaagaacaa
     9781 attgaaaatt atcaaaacgt gctttcagtc gaagaaatcg gtaccgtaac ttatgtaggt
     9841 gacgggatcg ctcgtgcaca tggtttagaa aacgcgatga gtggtgagtt gcttgaattt
     9901 tcaaacggct catacggaat ggcgcaaaac ttagagtcaa atgatgtagg tatcattatc
     9961 cttggcgatt tcgagtccat tcgtgaagga gataaagtaa aacgaacagg taagatcatg
    10021 gaagttccag ttggagaggc cttgatcggt cgggtagtca atccgctagg tcaaccaatc
    10081 gacggactag gtgaaatcgt tactgacaaa gctcgtccag tagaagcgat ggcaccaggt
    10141 gttatgcaac gtaaatctgt taacgaacca atgcaaacag ggctaaaagc gatcgacgcc
    10201 cttgtgccaa tcggacgcgg acaacgtgaa ttagtcatcg gtgaccgtaa aacagggaaa
    10261 acttctattg cgatcgatac gatcatcaac caaaaaggtc aagatatgat ctgtatctat
    10321 gtagcaatcg gacaaaaaga ttctacagtt cgtacacaag ttgaaacatt gaaaaaatat
    10381 ggcgcaatgg attacacaat cgttgtgaat gccggtgcgt ctcaaccagc accattgctt
    10441 tatatcgcac catatgctgg tactgcaatg ggtgaagaat tcatgtacaa cggtaaacat
    10501 gtattgatca tttttgatga tctttcaaaa caagctgttg cttatcgtga actttccttg
    10561 ctacttcgcc gtccaccagg tcgtgaagct tatcctgggg atgttttcta cttgcactca
    10621 cgtttattag aacgtgcagc aaaattaagt gatgatttag gtggcggttc aatgactgcc
    10681 ttaccatttg ttgaaacaca agctggagat atctctgctt atatcccaac aaacgttatt
    10741 tcgatcactg atggacaaat cttcttagaa agcgacttgt tctacgcagg tactcgtcca
    10801 gcggttgatg ccggactatc tgtatctcgt gtaggaggtt ctgcgcaaat caaagcaatg
    10861 aaaaaagttg ctgggacttt acgcctagac ttagcaagtt accgtgaatt agaagcattt
    10921 acacaattcg gttctgactt ggatgcagca acacaagcaa aactaaatcg tggacgccgt
    10981 acagtagaaa tcttgaaaca aaaattgcat gcaccgctag ctgttgaaaa acaagtagtg
    11041 attttgtatg ctttgacaca tggattctta gatagtatcc ctgtagacag tattttagac
    11101 ttcgaacatg aattattcga atatctggat accaatcatt cagatatctt tgaaacaatc
    11161 cgtacaacaa aagatcttcc agaagaagaa gcgttgaaca gtgcgattca ggaatataaa
    11221 gacatgttct tagctacaaa aggaagtaat tcctctacag aagataaatt gaaatccatt
    11281 caaaatgcat agtgaggtga gatgaatggg tgcttcatta aatgaaatca agacacgtat
    11341 cgcttcaacg aaaaaaacga gccaaatcac gcgggcaatg cagatggtgt ctgcttctaa
    11401 gttgacaaaa tctgaagctt cttcacagaa gtttcaggtt tatgcaacaa aagtaagaga
    11461 aatcgttacg catttgactg ctactcagtt aaatgatatt gcctcagaaa atcctagagg
    11521 ggatatcaat tacaacagca tgctgctcag ccgtcctgtg aagaaaactg gttatatcgt
    11581 catcactgca gatggcggtt tagtcggtgg atataacagc tcgatattga aacaaacgat
    11641 gtctatttta gaagaagacc accaatcacc cgatgattac gtgatgatcg caattggcgg
    11701 aactggtgca gacttcttta aagcacgcgg tatcaatcta gcatatgagc tgcgcaatct
    11761 atctgatcag ccaagctttg atgaagtccg caaaattgta aatatggcaa caactatgtt
    11821 ccaaaacgaa gtattcgatg aattatacgt atgttataac catcatatca attcgctaac
    11881 tagtcagttt cgtgtagaaa aaatgctgcc aatctcagac ttagatccag aagaagcaac
    11941 gactttcgaa caagaatata tttttgaacc ttcaaaagaa gaaatcttgt ctcagttatt
    12001 gcctcagtat gctgaaagtt tgatctacgg tgcgatcgtt gacgccaaaa cagcagaaca
    12061 tgctgctggt atgacagcaa tgaaaacagc aactgataat gctgctaata tcattgatga
    12121 gctgacggtt tcttataacc gtgcaagaca aggggctatt acccaagaaa ttaccgaaat
    12181 tgttgccgga gcttcggcac tagaatagta ttgagattgg aggaaaaaag atgagttcag
    12241 gcaagattgt tcaagtaatc ggtcccgttg tcgacgtgga attttcttta gaccaatcct
    12301 taccagatat caacaacgca ttagttgttt ataaaaatga cgaaaataaa tcaaaagttg
    12361 ttcttgaagc agcgttagaa ttaggggacg gagtgatccg gaccattgcg atggaatcaa
    12421 cagatggttt acaaagagga atggaagtca ttgatacagg caaagcaatc tctgttcctg
    12481 taggtaaaga aacattaggt cgcgtattca acgtactagg agatacgatc gatttagaaa
    12541 cacctttccc agaagatgcg gaaagaagcg aaattcataa aaaagcacca gcctttgacg
    12601 aattaagtac aagtacagaa attttggaaa cagggatcaa agttatcgat ttgcttgccc
    12661 catatttaaa aggtgggaaa gtcggactat tcggtggtgc cggtgttggt aaaaccgtac
    12721 tgatccaaga actgatccat aatatcgccc aagaacatgg tggtatttct gtatttaccg
    12781 gtgtaggtga acgtactcgt gaaggtaatg acttgtatta tgaaatgaaa gattcaggag
    12841 ttatcgaaaa aacagccatg gtgttcggac aaatgaacga accaccaggt gcacgtatgc
    12901 gtgttgcttt gactggtttg acgattgcgg aatatttccg tgatgtagaa ggtcaagatg
    12961 tactgttgtt tatcgacaac attttccgtt tcactcaagc tggatctgaa gtatcagcct
    13021 tgttaggacg gatgccttct gcggttggtt atcaaccaac attggcaaca gaaatgggtc
    13081 aattgcaaga acgtatcaca tctacgaaaa aaggttcgat cacatcgatc caagcaatct
    13141 atgtgccagc cgatgactac actgacccgg cgccggcaac agcattcgcc catttggatg
    13201 cgacaaccaa cttggaacgt aaattaacag aacaagggat ttatccagcg gtagatccat
    13261 tggcttcttc ttcaagtgct ttagcacctg aaatcgtggg agaagaacat tataaagtag
    13321 caacagaagt ccaacacgta ttgcaacgat atcgtgaatt acaagatatc attgctatct
    13381 taggtatgga tgaattatcc gatcaagaaa aagtgttagt ttctcgtgcc cgcagagtcc
    13441 aattcttctt gtcacaaaac tttaacgtgg ctgaacaatt tactggtctt ccaggttcat
    13501 atgtccctgt agaagaaaca gtgaaaggat tccgcgaaat cttggaaggc aaatacgatg
    13561 atcttcctga agaagctttc cgaagtgttg gccgaatcga agacgtcgta gaaaaagcga
    13621 aaacactagg ctactagaaa ggggtgcccc atggatcaat atttaacagt aaatgtggta
    13681 actcctgccg gtttggtcta tgatcaccat gcagctatcg tcgttgcacg tacgacagct
    13741 ggtgagcttg ggattttgcc taaacatgca ccaatcatcg ttccattgac gattgatgaa
    13801 gttcgtgtaa aacgaacaga ttcagatacc cacgtcgatt ggatcgctgt taatggcgga
    13861 atcatggaag ttcgtgataa tgttgtttca atcgttgctg atagtgcgga acgtgaacgt
    13921 gatatcgatg tatctcgtgc ggaacgtgca aaacaacgcg cagaacgcca aatcgaagaa
    13981 gcaaaagcaa aacaagatac gaacgaattg aaacgggcaa ctgttgcgtt gcaccgagca
    14041 atcaatcgta tcaaagtatc taagcactca taaaatgaga tgcggatgtt tatccgtgtt
    14101 taagaacagt aaaaagaggt tatgacagaa gtggtcagct tcaagacata agaaggaatt
    14161 tacgaaaatt gcttctcaaa tttttgtgaa atctcagctt atttttcgaa gaagctactt
    14221 ctggaacacc gtatatcaga ggttgtgaaa tcagcgtttt gtcctgagta ttagagaaac
    14281 aaatggaaaa tagttcctca tattttgccg ttttttgagc taataccgag ggtcagatga
    14341 ttgaacaccg tttatttgga ataagggact gcgacaagac ttttgtctca gtcccttttt
    14401 ttgcatattt ttagcattta tttcctaaaa aatgtaaggg gattcctata tttttaagta
    14461 tacttgtttt tccttttata cattttatgg tattatcatt ttattagtta ttataaaaca
    14521 atcgttagaa aggacgtcat tatgcaagta tacggaattg atgcggtgct tcgaatcgtg
    14581 agtcatttgg cgtttatcta cttagccttc tggtctttac gttcgttacg cattgaaact
    14641 tttttcagac caatgcataa tacgcaaatt agaatggcaa tcgtactttt ttcaattttt
    14701 ttagggtaca ctgcaagtaa ttttttctta gaggttatcg ctttatgccg aaatcttttc
    14761 gttagcctgt aaattttaaa aaaaggtact attttaaaag caaggatgtt ataatagaaa
    14821 agattttgag taagtgtatg ctcattggaa ttttttggag ggaacaacat ggaagagatc
    14881 atcgtaagag gtggcaatca attaaatgga acagtaagaa ttgaaggagc taaaaatgct
    14941 gttttgccta ttttagctgc tagtttgtta gcagaagaag gtattacgac attagacaac
    15001 gttccgattc tttctgatgt cttcactatg aatcaagtga ttcgtcactt aaacgtagat
    15061 gtagattttg atgaacaaaa gaatcaagta acaatcgacg cttcaagaca attagaaatc
    15121 gaagcgcctt atgagtatgt tagtcaaatg cgtgcttcaa tcgttgtgat gggtccgcta
    15181 cttgccagaa atggacatgc aaaagtagct atgcctggtg gatgtgcgat tggtaaacga
    15241 ccaatcgatt tgcatttaaa aggatttcaa gctttaggag caaaaattat tcaaaaaaac
    15301 ggctatatcg aagcaattgc ggatgaattg atcggtaaca cgatttattt agatttccct
    15361 agtgtaggtg ctactcaaaa tatcatgatg gctgccgtaa aagcaaaagg aacaaccatc
    15421 attgaaaacg tagctcgcga accagaaatc gttgatttag caaacatttt gaataaaatg
    15481 ggcgctcaag tctatggagc tggtactgaa acaatgcgta ttgaaggcgt ggatcattta
    15541 catgcagtca accactcaat cgtacaagat cgtatcgaag caggtacctt tatggttgct
    15601 gctgcaatga cacaaggcaa tgtgctgatt gcagatgcta tctctgaaca taaccgccca
    15661 ttgatttcta aattgatcga aatgggtgca gaaatcattg aagaagaagg cggagtccgt
    15721 gtcatcggac caaaacatat cttacctaca gatgtaaaaa cgatgcctca tcctggtttc
    15781 cctacagata tgcaagctca aatgacagct atccaattag ttgcagaagg tacaagtgtg
    15841 gtgactgaaa cagtgtttga aaatcgtttc caacatttag aagagatgcg ccgtatgaac
    15901 gctcatgtca aaatcgacgg aaatgtagca atcatggatg gaaaccatga attgcaaggt
    15961 gcagaagtat atgcaacaga cttgcgggca gcagcagcat tagttttagc tggcttgaaa
    16021 gcaaatggaa tcacacgtgt gcgtaacttg aattatctag accgtggata ttataatttc
    16081 catatcaaac tacagcaatt aggtgcagac gtcgaacgtg tagacatgga tcaaacttct
    16141 gctgaaaaaa cagcacaaac gattgcttaa ggaagtggct gaatgagtaa ccaacgatat
    16201 atcttattaa ctttgataaa gattttagtg gtgatcttat tgcttatcct tctttttgtg
    16261 gccggaacga tgatcggata tggtgtcatc ggtggcggca atccatttaa agtattccag
    16321 ccaagtttgt ggattcatat tcgagacttt tttcattgat aaataagaat cacagtggtt
    16381 ctagtcgata tgaagtgagc catgaagcag aacatgataa aagaaaacag aagggaacgt
    16441 tgacgttagt cgcgatccct ttttttagta aaagaaaaga aggaatctaa ttgatgaaga
    16501 agatattgat ttatttagtt agaggatatc agcgctttat ttcgcctgca tttccaccta
    16561 gctgccgtta ttacccaacc tgttccaatt atatgataaa agcaattcaa acccatggtg
    16621 cgctaaaagg gacggtaatg gggactgcac ggatcttacg ctgtcatcct tttgtcaaag
    16681 gcggtatcga ttatgtacca ttgacattcc gattaacgcg aaataagaaa gataaaaaag
    16741 aaccagatta taaaaaggtt gtgaaaaata cgggtagcac tgagcgataa agaaaaagag
    16801 gaaatttatt gtcaaagtaa caactccgca actacttata tgggggacaa aaaatgatcg
    16861 aagaactaaa caagaaagat ttaccatggt ccttgttatt agatgcagat cctgataaag
    16921 aaaaagttca agtatatgtt tccagaggga gtggctggat atggaaagaa aaagaaaaaa
    16981 caataggtgt actgatctat gtggcaaggg aaaaagaata cgaaatcgtc aatgtagcag
    17041 taaccccaac gtatcaagga aaggggattg gcggaaaatt acttgagaca gcttttcaga
    17101 agctttcaca gctagcttca aaccaaactc ggatcattat acgtactggc actactagta
    17161 gcgctgcgtt acacctctat caaaaaatgg gctatgtgga gattggtcga gtcaaagact
    17221 attttatcca tcattactct gagcccattt ttgaaaatgg agatcaatta agggatcaag
    17281 tgattttagc aattcactta cctaaaaata gctttaacta ataaactttc aattcgagaa
    17341 aatgctttca aatgctaaat agatacatta caatagcttt agcaaacaaa aaggagaata
    17401 tttttatggg aatattagtt tttgattttg gtggatcggc tgtcaaatat ggttgttggg
    17461 atggcaaaga gattaaaggt aagggacaat ttgcaacgcc tgaatcttgg gaagaaatga
    17521 aaacgcaatt atttcaagtt tataaaaaaa tactcgtttc ttttgaagtc gaaggaattg
    17581 gaatcagctc tcctggagta gtgaataatg agaaacaggt gattgaggga atcagtgcga
    17641 ttccttatat tcatggattt aatattttcc gagatttgga aactctgttt caactcccag
    17701 taacgattga aaatgacgcc aactgtgccg gaatggctga attttatgaa ggtgctgccc
    17761 gtgattatca agatgttgct tttgttgtgg caggaactgg gattggcggg gcgttgttca
    17821 cgaaaggaca aataaataaa ggggcacatc tttacggtgg agaatttggg ttgatgttct
    17881 tagatggcga taagacattc agtaaacttg gtacagcggt acagatggct tggcgttatt
    17941 gtgaacgcaa aggtctcgat aaaaatgctt ataccggaaa agatgtcttt gaattagcag
    18001 aaactggaga tgcaatagca aaagaagaag ttgagagttt ttatacgtat cttacaaagg
    18061 gattattcag tattcaattt tcgtttgatc cagaagtgat cgtattaggc ggcggggttt
    18121 ctgcaaaaga agggctcatt gatgagatca aaagccgaat gaagaagctg acagaacaat
    18181 tcgatctgca tgatttcgaa ccgcagattt tattatgtga gtacagaaac gatgctaatc
    18241 ttataggtgc agcagcaaac tatctcgctg tacgtcaagg agagaattaa gagctttaga
    18301 gaaggtgcag cttgcataaa agaagagaat gaaatgaata ggagattttt acctaaggaa
    18361 tgttttattt gctgcagtat gataaaatat ctgagaggtg aaaatgatgt caaaaaaaaa
    18421 taaagatatt gaagtgcgta tagaagaagt gaaaaaagat atcaaaggta agaattatga
    18481 agtcactcag ttatttatag ggaaaaaaat gattggtgag atcttagcct atgggccaaa
    18541 agaatatgaa attttctttg gtgaagaaga ttttggaaaa gaaaaaagtc ttgaaaatgc
    18601 gatagaaaca gtgattcgac actggaatct gcacgaataa aaaaatatca aaaaaacttt
    18661 caataaaggg ttgcaaaaat ctggaaaatt aggtattata actaagtcag gttgatacaa
    18721 acctttcgga ggagtagcga agtggctaaa cgcgacggac tgtaaatccg ttccttaggg
    18781 ttcagtggtt cgaatccact ctcctccatt tcattggggt atagccaagc ggtaaggcaa
    18841 gggactttga ctccctcatg cgttggttcg aatccagcta ccccagtata ccacaatcgt
    18901 aagctctcgt tagtt
//
LOCUS       DAFLWQ010000052        18770 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.053, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000052 DAFLWQ010000000
VERSION     DAFLWQ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18770
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.053"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..176
                     /locus_tag="L1V16_001839"
     CDS             <1..176
                     /locus_tag="L1V16_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBN1276179.1"
                     /translation="LISRQILYYSFCVPDSFSNYRISREVGYSERSIQRMKSEALIEF
                     AEAYKHGRIIAYK"
     gene            860..1027
                     /locus_tag="L1V16_001840"
     CDS             860..1027
                     /locus_tag="L1V16_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276180.1"
                     /translation="MYRPQYLEQKYEVITVQNGNGEIVRKYRRPIKSDTYKRKESNEV
                     IPLYGKRIAKH"
     gene            1053..1397
                     /locus_tag="L1V16_001841"
     CDS             1053..1397
                     /locus_tag="L1V16_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBN1276181.1"
                     /translation="MTEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            1402..1683
                     /locus_tag="L1V16_001842"
     CDS             1402..1683
                     /locus_tag="L1V16_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276182.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            1786..2100
                     /locus_tag="L1V16_001843"
     CDS             1786..2100
                     /locus_tag="L1V16_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HBN1276183.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            2078..3772
                     /locus_tag="L1V16_001844"
     CDS             2078..3772
                     /locus_tag="L1V16_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBN1276184.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            3792..4970
                     /locus_tag="L1V16_001845"
     CDS             3792..4970
                     /locus_tag="L1V16_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBN1276185.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            4933..5619
                     /locus_tag="L1V16_001846"
     CDS             4933..5619
                     /locus_tag="L1V16_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBN1276186.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            5619..6779
                     /locus_tag="L1V16_001847"
     CDS             5619..6779
                     /locus_tag="L1V16_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBN1276187.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            6789..7664
                     /locus_tag="L1V16_001848"
     CDS             6789..7664
                     /locus_tag="L1V16_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276188.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIKIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            7661..7972
                     /locus_tag="L1V16_001849"
     CDS             7661..7972
                     /locus_tag="L1V16_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276189.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            7962..8315
                     /locus_tag="L1V16_001850"
     CDS             7962..8315
                     /locus_tag="L1V16_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBN1276190.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            8305..8706
                     /locus_tag="L1V16_001851"
     CDS             8305..8706
                     /locus_tag="L1V16_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276191.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            8699..9103
                     /locus_tag="L1V16_001852"
     CDS             8699..9103
                     /locus_tag="L1V16_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276192.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            9115..9720
                     /locus_tag="L1V16_001853"
     CDS             9115..9720
                     /locus_tag="L1V16_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1276193.1"
                     /translation="MAKTTTVTTFDNISIKRISFNFKNATNAISTDCNGQLDGETEMQ
                     RIVKKCGSTEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDERIKSGIYSYGPDSVG
                     EDFSLAAEIVDDFEEKNKLIGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFGK
                     FYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            9740..10102
                     /locus_tag="L1V16_001854"
     CDS             9740..10102
                     /locus_tag="L1V16_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276194.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            10105..10287
                     /locus_tag="L1V16_001855"
     CDS             10105..10287
                     /locus_tag="L1V16_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276195.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            10304..13723
                     /locus_tag="L1V16_001856"
     CDS             10304..13723
                     /locus_tag="L1V16_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBN1276196.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASESEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLTKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITVIAGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQAFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWVSIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISSIFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
     gene            13774..14511
                     /locus_tag="L1V16_001857"
     CDS             13774..14511
                     /locus_tag="L1V16_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1276197.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVVGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINYFNCTGLSKIQIYRNGLR"
     gene            14521..16812
                     /locus_tag="L1V16_001858"
     CDS             14521..16812
                     /locus_tag="L1V16_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1276198.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYPISGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITASQAWQNAKTLAKPVIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKRLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            16836..>18770
                     /locus_tag="L1V16_001859"
     CDS             16836..>18770
                     /locus_tag="L1V16_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276199.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGEYDYSGNPNLMSKLKSSDFN
                     VGYHGSLTSDNEKLHFTSDGTGSIIMFTRINTPQLASGKTYTLSAKVRFDEGTTGAID
                     KLRLVYRTSPGEKILLEANSTNITTDDVGKEITIKGTANVNYQITNLDRFYMSISFVD
                     RDKINGGFKLYDIKIEEGSTATPYQPNLLDDPYWLGKAPLGENIANKSVTFPIKSSAY
                     SLYQANMEEEFVLGQTYTITMKATKPPIQTFIVYNEDSGDYRYGNLEPVEGLVDTWGL
                     TFTPQKVGVNYPKRLTIIQYPQSTVGACRIDWLKIEKGDTRTPNISEYKYRGTGMRDS
                     NNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINSQLTASINEVDTTA
                     KDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREGKTVSIYFVA
                     LNGKSSGGNDSTILTIPEGYR"
BASE COUNT         6635 a         2777 c         3955 g         5403 t
ORIGIN      
        1 gtctgattag ccgtcagata ctctactaca gcttttgtgt gccagatagc ttctcaaact
       61 acagaattag ccgtgaagtg ggttattcag aaagaagtat acaacggatg aagtcggaag
      121 ctctaataga gtttgcagaa gcatataaac acggaagaat aattgcttat aaataatttg
      181 gcggtttttt ggcggaatga tggcggtttt tagctattta ccagtgatat tatggtagtg
      241 tcgaaagatt agtgataggt ctgagacaaa ataataataa aaggaacatc gttttattat
      301 tgtttcacaa ttaagcttcg atagacagca acggaaatat taagaataag gatgtgaatt
      361 tcaactcctt ctaaattgtt cttattatct atcatccgtt gctgtctatt gtttttttaa
      421 ttattcacac gataactaaa ggtgagtgaa gagaaatgat tccattaata atttcaattt
      481 ttgcgctctg tcttaatgtc tatatgattg gatttaaaaa tgggcaaaat aaaaaatagt
      541 agcagccaag aataatttta tagtgtcact gtggcggaaa gggtagacgc ttaaaaataa
      601 ggtcaatacg tcgagggata gccttaacgt tttatgattt gaccatgcaa tgttcgattc
      661 attgccagtg actttggcaa ccgagggttg gaaatgggcg ctcaaagtac acgagcaagg
      721 cgaggtcgat agtaatcgat ggaatcggtg taggttgctt gatagagcta taactgcatc
      781 tcgtttatga ggtgtagttt ttacagatta gatcactctt tgagtggtct ttttatttta
      841 cacaaaggag gtaacaagaa tgtatagacc acaatactta gaacagaagt atgaagtaat
      901 cactgtgcaa aacggtaacg gtgagatagt acgaaagtat agaagaccaa taaagagcga
      961 tacatacaaa cgaaaggaaa gcaatgaagt tattccattg tatggcaaaa gaatagctaa
     1021 gcattaaata agattgcgaa aggagacgga atatgaccga ggaattctat agatggctat
     1081 tacagttgat aagagaagat cgtttggtta agttctatca gtctcctaaa tggcgcaggc
     1141 ttagagagaa agcgatgaaa cgagatcact atgaatgcca agagtgtaga agactaggta
     1201 agtatcatag agtagagaac gttcatcata taaaggaagt caaggataga cctgacttag
     1261 ctttagattt agataatctt atttgtttat gtgttgaaca tcataatgaa gttcatggca
     1321 gatatcttac agcgttagat aaacaagaga agaagataga aagcttcgct aacttcgatg
     1381 caagtgaaag gtggtaagtg catgatcatc aatgacaatg gcagagagta tgatacagaa
     1441 aagattgaag agtattcatc ttatactcag ggattaatta aacgtttgat atacgttcgc
     1501 tatgtaggta ttagggatct gttatcagat aactgttgta gtaaatacaa agtgaatcaa
     1561 gtaagagaag cgttgaataa agataataac gtcgaaagaa taaaaaatgt ttttggatat
     1621 agtattgaag agattaatta ttacattgac ttcgctgaag ctttcattcc gatggtgaga
     1681 taaccccccc ttaaaataaa tcgcaaattt tttgggggtg atgaaacgga gggggctgtc
     1741 aggaaaagag attttttcga actttatcat gaaaggaggg ctaaaatgtt taaaaacgaa
     1801 ttgtctcaaa atcgctacag agaaaaatta cgccgctctt taataagcca attggaaagt
     1861 cagaaaacaa atattgagcc attcttagat aatgttgatc gttatatcag tttatgggaa
     1921 acggcgatat cactggaaga agatatatcc gagaacggca ttagactgga gaatggtaaa
     1981 aagaatgaat cagtagcgtt gcttgtttct gtcaacaaac aaatgggatt gatgttggat
     2041 aaacttgcca ttactcctga attggtaggt gaagcaaatg aatcaattcc tgagttataa
     2101 gcatattgaa aattggttca aagctataga agaaggcact atcaaggtat gcaaagagca
     2161 attattgcta aaaaattatc tagaagaaag agtctttact agagaagata tttacttcga
     2221 taagcagatg gtagaggatt caatcaatat accagcacaa tactttccat tcgaattaat
     2281 tccgtgggaa aaatttctac aatgttttat ttatggtgtt cgatggaaaa aagataaaac
     2341 actagtgttc aatagatatc tttcattaat gggacgtggt aatggtaaaa ctggttttgc
     2401 ttcttggaac aacttctttc tactaaccgc taaacacggt attaaaaatt atgatattga
     2461 tatctatgcc aataatgaaa gccaagcaaa gactagtttt gatgatgtat ttaaagtaat
     2521 taaagatcat cctgatttag ataaaaaagt atttaaagct acgaaggaag ttattcaaaa
     2581 tatcgctaca aacagcaaac ttcgttataa cacggcaaat gctagaacaa aagatgggaa
     2641 gcgaccaggt gcaaaccgct ttgatgaaat tcacgaaaat gaagattatt caatgataaa
     2701 tgtggctact tctggtggtg gtaaaattcg agattataga gaattttatg atacaactaa
     2761 tggtcatgtt cgtggtggtc cgcttgatga cattatagaa gaatcaaaaa tgattctttc
     2821 tggagaactt ggaattgaca aggatggagc agaattttct agtttgtttc catttatttg
     2881 tcgcttggat aacgataatg aagttgatga tcccgacatg tgggaaaaag cttgtccaac
     2941 tattaattac aatgcagatt taaaacggaa aatgtttcaa gaatactctc aaatgcaacg
     3001 taatgctggt ttaagactta cgttcatgac caaacgaatg aacagaccta tggaagatac
     3061 acgatttgct gttgcttcat atgatgatgt tctgcatacg aaagaaaaag aatttcctga
     3121 aaaaatggat gaagtgatag gaacagtcga ttttgctgat agacgagatt ttgccagcgt
     3181 tgggttgcta ggaaaatacg ataaagatgt ttattttaca caacatactt ttatccacga
     3241 atcagccctt cgattacaaa acatcaaacg agaggttata gatatttcta tagatcaagg
     3301 aaaatcacag atcgttcatg gaaaaaatat agaagctgat tatattgtag gttggtttct
     3361 tgaaatgagt aataaatatt atattaaaaa aatcgctatg gatatgtacc gtgcaaaaat
     3421 attgaagccc gctttagaag aagcaggttt tactgtggaa attgttcgaa gcggatctgt
     3481 tacacatggt atgttaaaag atctggttga tgaccttttt attaatcaac gtttattttt
     3541 tggtgacgat gcgattatgc gttggtattg catgaatgta tatgaagagc atatttctaa
     3601 tggaaatata cgctatgaaa aaatagaacc tgaaactaga aaaacggatg gctttttttc
     3661 attccttcat ggtttgaatt ttttagatga tatttatgat tctgctcctg taacagtcac
     3721 aaatagctca gtagaaaata caggaactgg atttactcct ctagtattct aacttgaaag
     3781 gaggtgagaa agtggggatt tttcaaaagg cggtaggata cttcacaaaa aaagcaacgg
     3841 ttcctttaga agaatacttt tgtaaattgc aagttgattt tgtgtatcga aaatttgcga
     3901 ttgaaacttg tattgatttg attgcaaatg cgatgagtaa agcggaattc aagtcatatg
     3961 aagatggaaa aaataaaaag aatgatcttt actataggct gaatgtagct cctaataaga
     4021 aaaataatgc aacagaattt agaaaaaaac tgatcaggag attaatattc tacaatgaag
     4081 tattgatcgt ttctccgtct aataattcta gcgaaatatt tattgcggat agttgggatg
     4141 tcacagaata tgcattgaaa gatgatgtgt tttctcaagt gcaaattaac aacatagtcc
     4201 ttgatagaga atttctagaa agtgatgtta tctatataaa atacgcagat caacaaatta
     4261 ggcaactagt cgatgcgtat tatcaagcgt atgggaaact catttctagt gccatgaatg
     4321 tttacaagcg ctctaacgct cgtagatacg tactgaaagg gaatttattc cgaccgcaag
     4381 acaatacaac acaagatcaa atcaataaaa tgatgacatc acaatttaag gcttttatgg
     4441 aagctgataa tgcaggtgcg gtatttcaat tacaaaatga gtacacatta gaagatttca
     4501 gcggaaactt ccaaagcaat tcaagagata taaaaaactt aatagacgac atctttgaga
     4561 tgacagcagc agcgtttcac gttccgaaaa acctactaaa gggagacatg agtgggttat
     4621 cggatcaagt ggacgctttt ttaatgttcg aaatcatacc gattgctgaa cttattcagg
     4681 atgcgtttaa cgctagtctc tatgaagtag aagaatactt gtcagggaat tttgtacgtg
     4741 tggatacaac tatgatcaag attactagct tcaaagattt ggttgacgct attgatgtag
     4801 gcattagaaa tggagtattt acaatcaacg aaggaagaga gcgcgttgga aatgatcgct
     4861 ctgataaggc gatggcagat gaaatattta taactaaaaa caatcaacaa gtatcgaaag
     4921 gaggtgaggc gaatgacgac aatgaaaaca tttctagcag taaagaatga aggcgcagta
     4981 ccgcaaattt ttattcaggg atttattggt tctagttggt tctttgaagg gaatactgac
     5041 aagggaatca aaaatatttt ggatagtcta ggtgatcaag aagaaattga agtagtaatt
     5101 aattcaaacg gtggagacgt atttcaaggg attgctattg ggaacttact taagtcaaat
     5161 aaagcaaaag ttaacgttgt gattaacggc ttagccgcta gtgctgcttc aattatcgca
     5221 atggctggcg atactataaa aatctacaac aatgcacaat tgatgattca ccgcgcttcc
     5281 acatacggag aaggaaatgt cgatgacttc cgtacgattg ctgaccaact ggaatcaatt
     5341 gataaatcgg taaaggcttc atataaaaca cgattcaatg gcacagatga agcattgcaa
     5401 gaacttcttg aaaaagaatc gtttatggat gcagaaacag ctttgagtta tggattggtc
     5461 gatgaaatta tcgatgcaga aaatagctca ggtactgaag ctaaaaaaga acaaagcgtt
     5521 gaagaaattt tgaatgacgt taaagaaaaa agagcagaaa aaattgctgc atttacagca
     5581 gcattaaata aaacatttgg acaaggagat gtaaaataat gacagttaaa aatttaaaag
     5641 gtgtaacagc tgcaagcgac caattgatga aagcttttaa agatggtaac gaagaatctt
     5701 ttagcgcagc tatggtaagc ttatctaagg aaattcagga taaaatttta gaagaagcaa
     5761 cagcaaaaaa tcaagatcaa ttagtattaa tgaaccgtgg tcagcgtgta ttaactacac
     5821 aagaaacaaa attctataac gaagtagtga aaaacgaagg ttttgcaggg gtcgaagaat
     5881 tagtgccagc tactgtattt gaacgtgtat ttgaagattt agaacaatct catccactat
     5941 tgcaaaaaat tacttttgtt aacacaactg gtgtaacaga atggattgtg tcacgtggag
     6001 tcaatccagc atggtggggt aaactttgcg aagctgttaa aaaagtttta gataatggct
     6061 ttgatgtaat taacatgaag cagttcaagc tatcaggtta tattcctgta tgtaaggcaa
     6121 tgcttgattt aggtccagta tggttagatc gttatgtccg tactgtttta gtagaatcat
     6181 tgagaattgc attagaacaa gcaattgttg atggtactgg taaagatatg ccagtcggaa
     6241 tgatgcgtga catgagcaaa caaactagcg gagaatatgc tgaaaaaaaa gcagaaccta
     6301 ttacagcttt agatgctgta actatgggcg gtttgatggc gcgactatca aaattcaata
     6361 tcgaaggtgt gaatgatccg atttatcgta atgtgaatcc ttctgatgtg gtcctaattg
     6421 tgaatccaac tgattactgg tctaaagtat tcccagctaa gactgtacta actgctaatg
     6481 gagaatacgt acaagtattg ccagtaccag tttcagattt gcagtcaacg gctgtgccag
     6541 aaggaaaagc agttattggg gtagcctcag attacttcat gggtgtagga tctacactaa
     6601 aaattgaagc ttcagatgaa taccattttg ttgaagacga acgcatttat ctagctaaac
     6661 aatatgcaaa cggtcaacct aaacgtaacg atagtttcat tgtattagat attagcgctt
     6721 tgggaactac tactacaact acaaaaccaa caaccacaac aactacaaca caagcgtagg
     6781 tgatcagaat gaagtatatt ctttgtcagc cggcaatcaa tcggtttaaa tgggagcttg
     6841 aagtttgttt aactaatctg aagaaactag gaatcaaaga tatcgtattg cttttcagca
     6901 gacacgatga tcagattcct attttttttg agaaggaata tggtgttgaa gttcatgtgt
     6961 acgatgatct gcgggacgac aaagagtata ttccttcgat taaaccatat ttatggtgga
     7021 aatatttaga agaagatcat tcgcgtgagg acgaccgata tttctatatc gattcggatg
     7081 tcattttcaa taaaagaatt aatttgcgca aattgccttc taaagatgat gtttggtatt
     7141 gtagcgactg ctgtagttat ctaagtcttg attatattag aagctgtgaa aacggagaaa
     7201 atattctaaa agatatggca aacattgtaa atgttacagt agaatctttg gaaactataa
     7261 acactaattc aggaggcgca cagtgggtta ttaaccgccc taaagcgaat tattggaaaa
     7321 aggtttatct ggattctaat cggctatatc gctaccttag agggcaaaaa acaaatataa
     7381 aaatctggac agccgagatg tgggcacagc tttggaacat gatgtatttc aatattggtc
     7441 ctaaagttca cgaggaatta gacttttgtt ttgctactga tccaatagaa aaagttaaag
     7501 aagtaaaaat cttacacaat gctggagtaa caacaaacga tgaagattta tttttcaaag
     7561 ggagatacgt gacttctacg ccttttgatg aagatttatc atttgtaaac aagaaaaaat
     7621 gctcttacgc atatgttaaa gcaattaagg cggtggttag atgacgcctg aacaagtgac
     7681 tgaagaattg ctaatagctg tgaaggataa tatttacgtt acctggaacg aagaagatga
     7741 gtcaattaaa aagatgatag ctaaaaatgc tgtttatctt caaagtaaag tgagtacaac
     7801 actttctttt tctcctgaaa gcttagaata cggattgcta atcgaaagat gtagatacga
     7861 ctggaatcgt gctttagatg agtttgaaca aaatttcgct agtgagttat taggtttcat
     7921 tcaacattat gcgctacaag aatatattgc aggtgatgtg aatggcgaat aatcgtagac
     7981 tcgaagaaac attcaacgat ggttggttaa agattttgac gcaaactacc aaaagaaatg
     8041 aactaggaaa aaagattggt gtagaagata cagaaatcac ttctttaaaa tttagaaatc
     8101 tttccatgag agatagtgat ataacagcta tggatgcgat gggatcgaaa ttaactaaga
     8161 aagtaaagac tccatttcat ccaatcgcca agaaatttaa taaagatcaa tattttatcg
     8221 taatcgatag tatgcgttac aacgttatct atgccgatta cgataatttt tatatctatt
     8281 tttatcttga aagtgtgggt gaatatggtg attgataatt ctaaagaaaa agaacgttta
     8341 aataagcaaa tttctgctat caaaacttcc ttagaagagc attttggcct caaactcttt
     8401 caagactccg taggcgagga tgagctacct gatgatttta attacttcat tctcgaaaca
     8461 ggagaaatag aaatgatcac tgagccaaaa tatagcgtgg gtcaaaatct atatctaact
     8521 ttctattcag aaaatagaga agatttaaca ggagattcac tagatattat ttcattgatt
     8581 caaaatcgtt cgattcgttt tcagagaatg gatcccaatc atttaaaact agagaaccaa
     8641 gatcgctata tcgatcaatt ggtatttacg tttagacgat tattgaagag tgattgtcat
     8701 ggctaaaaat agttgggagc taaaaataaa tggacatgat gaacttcttg tgcggatgga
     8761 acgctattca agcgagagcg aacgactgat taacgaagca ttgaaatcaa aaggttcggc
     8821 tattgcagtg gataggatta cagaaaaaat tcctgtttct gaagcagatt taagaagagg
     8881 gcaccaacac gcaaaaaata gtcgtccact taagactcaa tacattaatt tgggtttcat
     8941 cattagacct acaagaaaat ttgagtattt aaaatatcct gatttgggga taggtacttc
     9001 taaaagaaat cagccggacg aatttatgag aagaggatta ggtcttgcac ttgatccaat
     9061 tacagaactt ctgattcgtc aattcgataa attaaataaa taggaggaac aacaatggct
     9121 aaaacaacaa cagtaacaac ttttgacaat ataagtatta aaagaatttc ttttaatttt
     9181 aagaatgcaa caaatgcaat ttcaactgat tgtaatggac aattagatgg cgaaacagaa
     9241 atgcagagaa ttgtaaaaaa atgcggttca acagaagtaa aatcgaaatc taaaccaatc
     9301 aatatgacgg taacaattac tgcacatgta ccgatggaag tttatcgacg cttcaatggg
     9361 ttgaaacaag atgaacgtat taaatcggga atttactctt atggtcctga ttccgtaggg
     9421 gaagatttct ctcttgctgc agagatcgtg gatgatttcg aagaaaaaaa taagctgatt
     9481 ggtatgttag catgcacttc gaatacagga ttaacattct ctattgaaaa tggtgcggat
     9541 gaagtagctg cgttagaact agaaacaaaa gttatgcaag atgaatttgg taaattttat
     9601 catgaagcaa ttgttgcaga acttgaagaa gacttaacag atcaatggat gacgaatcta
     9661 tctgctgatg tgattaaaaa aacttcagtt gtgacaacta cggccactca atcacagtaa
     9721 aaaaaacgga ggtagcgaaa tgaacgaaga ttactcaaaa attgaactaa acgatggaac
     9781 aattttgaat ttagaaccta aactgaatat caagaaatta ttgatgatca atagagattt
     9841 taacacagac gagtttgcaa aaatgactgt gggaaaagga tccatggata tttctgttat
     9901 tcaaggtgca aaggctgtgt atattgctta ccgccaagcg aacatgactg attatatttc
     9961 attcgatgaa tttatcgata aatgggattt tgatatggct actgccagct atatttatca
    10021 attgatgatg ttcaaacaag cacgcgatgc ttatcaaaaa gaatttgaaa aagcaaataa
    10081 ggaaaaaaag cttcaaaagt aaaaatgcca aagctcttag ttgaaacgtg ggtcgatgtc
    10141 tattcgatgt tgaccgacgt tttttctatg ccttcagatt tggttttaag cgatatctgt
    10201 ttagatgaca ttttgcaaat ggcttacaac aagagtgctt atgaaggatg gaaaaactat
    10261 gcaataaacc aatcccagaa aaactaaaga aaggaggtaa aaaatggcta aaaagagaac
    10321 agaagcagaa gtaacattca tagctaacga tgacggattg aaatctacgt taaaagaaat
    10381 cagtgctgaa ttaactaaaa atagagcaga attaaaacta gaacaagctc aattacaaca
    10441 gactggttct gaatcagaca agttaggaag taaattatct tctttagaaa agcagtatga
    10501 attacaaagt caaaaagttg aagtaactag ccaacgttta gccaatgcca aaaaatatta
    10561 tggagaaaat tccaccgaag ttcagaaact tgagagagaa ctgattaacc aacaaacagc
    10621 gcaacaacgt ttgtcaaacg aaattgataa aacgagtaat gcactagctc aagcaaaagg
    10681 cgaaatacag acgtacgagt ctacaatgca acagttggat agtgaacaaa aaaatgttca
    10741 agctagtgct tctctgattg aatccgaata caaaaaatgg caagcaactg ctggtcaatc
    10801 agcttctgaa tccgagaaat tagcgaaagc ccaagaatat gtttctcaac aatctgaaaa
    10861 tgcagagaaa acgatagata tcctgagacg acagttagaa gctacacagt ctgagtttgg
    10921 cgctacatcc acagaagcaa tgcagatgga ggcgaagctt aatgatgctg aacgtgaatt
    10981 tgaagagtta ggacaagctg ctaaaaatgt agatacaact aacttggacg atatcggaag
    11041 caaaatagat atgaataatc taatggaagc ttctgacgtt ttaagcgaca ttggcgataa
    11101 gcttacagaa ttagggaaac aagcagtgga ctctgctaat agtgtaggta gttcccagag
    11161 taaaatacaa gctaattttg gtttgactaa acaagaggct gaagaattaa cgaatgtagc
    11221 cagagacatt tattataaag gttttggaga atcgttagat cagtccacag atgcattgat
    11281 tttggtaaag cgtaatttag gcgatttaaa taatcaagat ttacaaaata tcacggaaca
    11341 agctatggtc ctagaaaaca ccatgggcgc tgatatggat gaaacgttac gtggtgtaaa
    11401 tggcttaatg gtcaatttcg gcttgagcgc tcaagatgca atggatttaa tggtttcggg
    11461 tactcaaaac ggtttagata aaacgcacga attaggcgac aatatggcag aatatagcca
    11521 attatggagt caaatgggat attcagctga tgaaacgttc ggaatgcttc aaaatggttt
    11581 agatgcgggt gcttataacc ttgataaagt caatgactta gttaaggaaa tgggaatatc
    11641 gttaacagat ggtcgatttg agcaaaacat ggatatgttt agtgaaagta ctagaaaagc
    11701 ttttgaagag tggaaaaatg gcggaggaac acaaaaagac gttattaatt ccatgattca
    11761 agattttagc aatatggatg gtcaatacga ccaattaaat aaagcttcta caatttggtc
    11821 tgcacttggc gaagataacg cgatgaaagt tgtccaatct ttgactgatg ttaaccatac
    11881 atttgatgat gttagtggat ctgcacaaaa aatgaatgaa gattctacta ctccgttaca
    11941 agaattaaac ggaaaaatag ctgaattaaa ggattcatta gctcctatag gcaacacaat
    12001 catagatgca ctcgaaccag taattgattt tctaggaaag atggctgatg cgtttaataa
    12061 tcttccacaa ccagtacagg attatgccgt agcgattggc ggattgactg ctgcatttac
    12121 tttattaatg ccaataatag ttggcttcat ggctctaggt ggtcctacta cattaataat
    12181 aggagcagtt attactgtta ttgctggagt tatagcaatt ataaaaaact ggggcgcaat
    12241 tactgactgg tttaagggaa tatggagtaa attcactgat tggttgggtg gtacttggga
    12301 aagtataaaa gaaggtgcct catcagtttg ggatggagtt aaagaaacct ggtctggatt
    12361 tgtagattgg gttcaagata tttggcaagg agtttctgat tggtttggag agctatggag
    12421 cggattagtt gaaggagctt ccaacatctg gcaaggagtc caagagactt ggcaagcatt
    12481 cgttgattgg gtttcaaata tttggaacgg agtcaaagaa gtatggtcga ttatttgggc
    12541 agacattgta ggaattgttc aaataccatg gaccttaata acgtcattga ttcaagccgg
    12601 tattaatatt atcgtgggta tttttgatgt agctggacag ttattaggcg cagcttggca
    12661 agctgtttgg acacctattt ctgatttcct taaaaacact tgggatacta tgacacaatg
    12721 ggtaagcatc gcttggaatg gaattgtaac tacattccat actatatttg atccagtagt
    12781 ggcatggtgg aatggtatat ggacagctat tagtactacg gcttcaaata tttggaattc
    12841 aattagtgca acagcttcta gtatttggaa cagtatcaag aatacaatca ctagcttggt
    12901 acaagcagct gctacagtaa ttcaaaatat ttggtcaact gtatctagtt ggttaggtgg
    12961 aatttggaat tcaatcagct ctacagcatc aaatatctgg aatagcgtga ctagtagtat
    13021 aagcaatgct ataaacgcag ctaaaagtgc cattcaaagt gtttggaata gtatatcttc
    13081 gtggatcagc ggaatttgga acggtatcaa aaacactgct ttgaatcttt ggaatggaat
    13141 tacaagcact attagctcta aagtaaacga tggaaaaaat gcaatttcaa gcggttggtc
    13201 caatctaaca ggtattgttt ccgacatatt caataatgtt aaaagtacaa ttgctaacat
    13261 ttgggaaggt atcaaaaaga ctgttagcgc tccaattgat tggatcagag ataaaatcag
    13321 tagtatcttt gataatttga atatttctat accacatatt ccgttaccac attttaaatt
    13381 gagcggagaa ttcaatccat tgaaggggaa aatcccaacg ttgggtgttg attggtatgc
    13441 gaaaggtagt gtgtttaatt ctccgaatat tatcggtgtc ggcgaagcag gacctgaagc
    13501 agttttacct ttgaaaagat ctgtgctgca agaaattggt gatcgtatct tgagtagcac
    13561 atcagtttca tctagggcac aaacgattca acctgtgaat aactacgaat tcaatttcac
    13621 aattgatggt aacgcagatg aggttactat gaagcaaaca actcaacaaa tcattgatag
    13681 cattacaaaa gttcaaaatg ataatgcttc ggcatggcgt taaacaggag agtatttctc
    13741 ctgttttttt agtattaaaa aggatgtgaa aaaatgactg attgtataca ttctataatc
    13801 gatggatttc ctgattattt gcataaattg gctttagctg aaagaccaac cataccttct
    13861 ccaaaaagac agagagttga aacttctgtt ttaggaaggt taggtggctt agtacaagat
    13921 tactcgtttg aagacatgtc gtttacattg cactataact atttagagga tgtggaagac
    13981 catcaagcgt tcaagcaatc gttttatatc atgcgtcatt ggttaaatta tgcaaagaaa
    14041 ttagaattct ctgatgatcc caacgtctat tatgttatcc agactatcga tattggggat
    14101 gcagaaaacg atattgttga atggggagag ttcgatgtaa atattactgc gaaaccattc
    14161 gcaagagttc aagaagatgt acctataacc gtagataaac cacagtcatt taacttgctg
    14221 aataatagtt tagaagaaag ttttccaaag attatcatca ctccttcagc tacttcatgc
    14281 cagttcatct taaatgatta tgtgtttagt tttgaaggct tagtagtagg aactgacgta
    14341 gtcattgata gtgatttgat gctttgctac gaagagcaat cggacggaga tattttagat
    14401 cggtccaaca aaatgaagac catgcaatat ccgacattgc aagtggatat taattatttt
    14461 aattgtactg gtttgagcaa aatacaaatt tatcgtaatg ggttaaggta ggtgaaatag
    14521 atgatcgata atttaataac tatttacgat aaaaacgacg cgaataattt agctgaacat
    14581 ttatatgata cgcaaggttt aggcgctttg tcagactggt taacagctac tgttagcaat
    14641 aaattaaacg gagccgagat atttcagggt acttatccaa taagcggaac taatgcagat
    14701 ttgattgtag aaggacgtat tattcagtgt tatgtagatg aaaatcgagc aaaacagcgt
    14761 ctacggattt attatgcaaa gacttctgta ataggcaata cgatagaagt aaaagctgaa
    14821 cctattttca atgatataag aaaatcggtg ttgaataaat atgacagtgg aacagaaaag
    14881 atcactgcta gtcaggcatg gcaaaacgca aaaactttag cgaaaccagt tattccttca
    14941 cagttttctt tctcgtcatt agtagatacg cttgctaatg tgaagataga aaaggcgaat
    15001 tttttagaat tctttggtgg aaaagaggga tctattctag atcgatttca tggggaattt
    15061 ctaaaagata ataacacatt acgtcatgaa aaaaggctag gcacggatca taaaatcaaa
    15121 gcgatttata ctaaaaactt aactggtctt gacttagaga ttgatgctca aagtgtttta
    15181 gttggagttt atccattcat tagcagctct tcagaaggag aagacgagat cactctacca
    15241 gaagaagtta ttttcacgga ttacgtggat gattatcctg ctggatatgt ttcttttgtt
    15301 gattttaaag acaaagcgac tgatgtagcc acattaaggg aagctgctaa agactggttg
    15361 aaaacaaaca tagataaaca aaaaccacaa gtgagtggtt cgattgaatt agtaccattg
    15421 aggcatcaaa gaggctatga aaaatttgtt gatctagaaa aagtttcgat gggtgacgga
    15481 gtagatgtgt atcatccaca gttaaaagtg aatatgtcag cgagaattgt ggaatatacg
    15541 tttaatgttc taaccaattc atacgataaa ttagttgtag gaaacgtcaa aacaaacttc
    15601 ttagaaaaca cagagaataa tgtcagcaat ttgattaatg atgccattga tcaattgaaa
    15661 aacggtggcg aaatcagtga tttactcaat gatattgtag atcatcaaac tgatatgatt
    15721 actggtcaaa atggtggtta tgttttatta gatcctaaag aagcgcctag tcgtattttg
    15781 attatggaca caccagataa gaataccgca aggaatgttt tacaaatcaa caatgctggt
    15841 attggttttt ctaaaactgg cattaatgga acatatgaaa cggcatggac gttagatggc
    15901 ggattcaatg cctcgtttat tacggctggt gaaatagtag gaattactat tagaggtact
    15961 acattaatta gtgatggtgc tgattataga acaagtattg ctaatggcaa aatgacttgg
    16021 tactcaaaaa aagttaacaa agatattatg gagctagaag cacgtgatta tgtaagtgct
    16081 gatgccggta ttgtatcata caccatgaaa actggtggtg gtttcatgat tagaaatcca
    16141 cagggtaact tggtttttag tacgtgggat aatggtaata acagaccgtt tctatctttt
    16201 ggtgcgccca atttcaggta tagcaatgct agttatgtaa cttctggcga cggtagttct
    16261 ttaagcatta atggtagtgc gggtaactca tgggaattta aggtagctgg taggactatg
    16321 aaatttacta gtgatggtat gctaacgtta ccaggttgtt tttttggttc atgggaagat
    16381 gggaaacttg ctaggtttga acaatcaacg gtacaagtat ataaagattt tactgttaga
    16441 ggtactaaaa actcaactgt accaacagaa cattatggac aacgactatt gaacgcttat
    16501 gaaactccag aatattattt cgctgattat ggggaagccg ttacaggtga cgatggtaaa
    16561 gttcgtgttg atattgaccc catgtttgct gaaacagtaa atctaagtcg gtatatgaca
    16621 catgtgacac ctacagaact agttttgtgt gctgttactc atgaagatat tgaccatttc
    16681 atcattgaaa ctagtaagcc aaacgtatta gttagatgga atttagtggc acaccgtcta
    16741 gggtatgaag atattagatt aaaagaggat acagcatatg atagcacagt gcttgaccaa
    16801 aaacgttttt aaaacgaaga caaggaggta tataaatggc tagcagttta tataatttgg
    16861 ctttagattt cagcaaagaa ttaaactaca ccaaagctat tatggctcgt caaggtgata
    16921 aagggattac ggtgacggtt aaaccgtttc taaatggctt gcagatggat acgagtggcg
    16981 gaacatttac tttaaaagga acaacaccat ctaaccgtta cgtagataat gttgcaacta
    17041 gtgtaactag tgaagaagtc acgttttctc ttgatggcac atttatgagt gaagcaggat
    17101 attataaaca ctgctacgta gaatatagaa aagacaatca aattttaaca acgcaagata
    17161 tcattttttt ctcactagga gtgtctgaca tttcgcaagg ccaagccgat gaatatgttt
    17221 cgcaattaga agagttgatt cgaaagtaca acgaaacttt tgatgctttt atggctgaaa
    17281 tcaaaggtag agtggatagc ttaaatcaac agattactga tttaactggt caagctaaaa
    17341 cgctacaaga caagttagat gctctgaaag aagaaatttc taagttaggt aacttacaag
    17401 tgatgtacag taacagcatc gatttcgggg aatatgatta tagtgggaat ccgaatttaa
    17461 tgtccaaact aaaatcgagc gattttaacg ttggttacca cgggtcacta acttcggata
    17521 acgaaaagct acattttact tctgatggta caggaagcat tattatgttt acgcgtatta
    17581 atacacctca gcttgctagt gggaaaacct atactctgag tgcgaaagtt cgatttgatg
    17641 aaggaactac aggagctatt gataaattac gtttggtgta tcgtacatca ccaggagaaa
    17701 agatattatt ggaagcaaat agtacaaata ttacaacaga tgatgtaggg aaagaaataa
    17761 caatcaaagg tacagctaac gttaattatc aaatcacaaa tttagatcga ttttatatga
    17821 gtattagctt tgttgacagg gataaaataa atggcggatt taagttgtac gacatcaaaa
    17881 tcgaagaagg ctcaacagcc accccatatc agccaaactt acttgatgac ccttactggc
    17941 taggtaaagc gcctttgggt gagaatattg ctaataagtc tgttacgttt ccaatcaaat
    18001 ctagcgccta cagcctatac caagctaaca tggaagaaga atttgtttta ggtcaaacct
    18061 atacaattac catgaaggca accaaaccac ctatccaaac gttcattgtt tacaacgagg
    18121 atagtggaga ttatagatat ggtaacttag agccagtaga agggttagtt gatacatggg
    18181 gtctgacttt tacaccgcag aaggttggag ttaactaccc caaacggtta actattatcc
    18241 agtatccaca atcaacagta ggcgcatgcc ggatcgactg gctcaagatt gaaaaaggcg
    18301 acacacgaac cccgaatatt agtgagtata aatatcgtgg tactggtatg cgtgattcaa
    18361 acaatccaaa agattatgtt tgggatctag caccagaata tgtcgaagat aacttggcca
    18421 cagatattaa aatttctgaa attactggta aagcaaacaa ttataccgat gggaaagtat
    18481 cggagattaa ttcgcagttg actgcttcaa ttaatgaagt agacaccaca gctaaggatg
    18541 ctcaaacaaa agcgaatgct aatgcgactg ctatagatga attagacaat aagatcgatg
    18601 aacgcattaa tgatacagct actaccacat taacagttac aaacgggaat accggatcag
    18661 caaagcttta tcgtgaagga aaaacagttt ctatatattt tgtggcttta aacggaaaaa
    18721 gcagtggtgg aaatgattca acgatactaa caattccaga aggctatcgg
//
LOCUS       DAFLWQ010000053        18547 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.054, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000053 DAFLWQ010000000
VERSION     DAFLWQ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18547
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.054"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            96..530
                     /locus_tag="L1V16_001860"
     CDS             96..530
                     /locus_tag="L1V16_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1276200.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(608..1141)
                     /locus_tag="L1V16_001861"
     CDS             complement(608..1141)
                     /locus_tag="L1V16_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HBN1276201.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(1235..2413)
                     /gene="mutY"
                     /locus_tag="L1V16_001862"
     CDS             complement(1235..2413)
                     /gene="mutY"
                     /locus_tag="L1V16_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBN1276202.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(2406..3203)
                     /gene="recX"
                     /locus_tag="L1V16_001863"
     CDS             complement(2406..3203)
                     /gene="recX"
                     /locus_tag="L1V16_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBN1276203.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            3310..4692
                     /gene="rlmD"
                     /locus_tag="L1V16_001864"
     CDS             3310..4692
                     /gene="rlmD"
                     /locus_tag="L1V16_001864"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBN1276204.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(4866..5444)
                     /locus_tag="L1V16_001865"
     CDS             complement(4866..5444)
                     /locus_tag="L1V16_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HBN1276205.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            5766..6236
                     /locus_tag="L1V16_001866"
     CDS             5766..6236
                     /locus_tag="L1V16_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBN1276206.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(6344..7570)
                     /locus_tag="L1V16_001867"
     CDS             complement(6344..7570)
                     /locus_tag="L1V16_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBN1276207.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(8324..8524)
                     /locus_tag="L1V16_001868"
     CDS             complement(8324..8524)
                     /locus_tag="L1V16_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBN1276208.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(8658..9266)
                     /locus_tag="L1V16_001869"
     CDS             complement(8658..9266)
                     /locus_tag="L1V16_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBN1276209.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(9351..9821)
                     /locus_tag="L1V16_001870"
     CDS             complement(9351..9821)
                     /locus_tag="L1V16_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBN1276210.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(9869..10783)
                     /locus_tag="L1V16_001871"
     CDS             complement(9869..10783)
                     /locus_tag="L1V16_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBN1276211.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            10929..11732
                     /locus_tag="L1V16_001872"
     CDS             10929..11732
                     /locus_tag="L1V16_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HBN1276212.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            11910..12857
                     /locus_tag="L1V16_001873"
     CDS             11910..12857
                     /locus_tag="L1V16_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBN1276213.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(12925..13218)
                     /locus_tag="L1V16_001874"
     CDS             complement(12925..13218)
                     /locus_tag="L1V16_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HBN1276214.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(13246..13911)
                     /locus_tag="L1V16_001875"
     CDS             complement(13246..13911)
                     /locus_tag="L1V16_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBN1276215.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(14051..14683)
                     /locus_tag="L1V16_001876"
     CDS             complement(14051..14683)
                     /locus_tag="L1V16_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1276216.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(14690..15757)
                     /locus_tag="L1V16_001877"
     CDS             complement(14690..15757)
                     /locus_tag="L1V16_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBN1276217.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(15754..16485)
                     /locus_tag="L1V16_001878"
     CDS             complement(15754..16485)
                     /locus_tag="L1V16_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HBN1276218.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(16654..17133)
                     /gene="greA"
                     /locus_tag="L1V16_001879"
     CDS             complement(16654..17133)
                     /gene="greA"
                     /locus_tag="L1V16_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBN1276219.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(17269..18444)
                     /gene="mltG"
                     /locus_tag="L1V16_001880"
     CDS             complement(17269..18444)
                     /gene="mltG"
                     /locus_tag="L1V16_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBN1276220.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
BASE COUNT         5520 a         3743 c         2980 g         6304 t
ORIGIN      
        1 aaattctttt attctttttt tatttttgaa aacttgccat actttttatt tgttttattt
       61 tccagtatac tatacgaaag gaaggtggct agaccatgaa agttgtacaa acaaaagata
      121 caatgagcaa tatttactta gatgctgtac ggatcaggca tcaagttttt gtagtcgaac
      181 agggtgtgcc tttgtctcga gaaatagaca aagatgaagc ccattgtatc cacttcgtcc
      241 tgtactcaga taaaaaagaa ccgcaaggaa ctgtacgtct tttgccttta gaaaacggaa
      301 aaatgaaatt acagcggatg gcgattcttt ctgaatacag acaccaaggg ttaggaaaaa
      361 tattgattga agaagcagaa aactttgcta agaatcaagg ctataatacg attttattag
      421 gggcacagtc cacagctgaa actttttacg aaaaactagg atatacagct tacggcgatc
      481 cttttgaaga tgctggcatg cctcatattt atatgaaaaa gactttataa aaatttattt
      541 cgaaaaaagc aaaaaacagc aagcttttga gaaaaatctc tcactggctt actgttcttt
      601 tttgtgttta cttacgcgac aattgcttgt aacggttata ccaaatatca atatagcctt
      661 ccgagaacgg gccatctcca ttattgatcc agtcaaccag aatcttcaca ttttctttta
      721 ggatgaagtc aatatcgttc gggtaattca tcattttgct gtgcatctca tattcatcga
      781 catccaatag tcgtttctcg ccgtcaggaa ataccttgat atccaagtca tagtcgatat
      841 atttcaaggc ctcatcgtcc agcaaaaaag gtgaagctag attacaataa taggaaaccc
      901 ccttttctct gatcattgct attacattga accagtattt tttatgaaaa taaacaatcg
      961 ctggttcgcg cgttacccat cggcgtccat cagattcagt gactaatgtg tgatcattca
     1021 cgccgatcat agagtgttcg cttgttttta ataccatggt atctcgccac gttcgatgca
     1081 atttgccgtc gtgcttgtaa ctttggatcg tcacaaactc tccttctttt ggaactccca
     1141 tagcaaccct tccttaagca gcattttgtg ctttgtgttt gggtgttcat tacaccgaca
     1201 tcataattat tatatcaata aaaatgagct ttgcctagaa aggattccta ttgtttcgat
     1261 ttttctctaa ctgatctacc agtttcattt ggaccttagg aaaaacgacc gaatcaaatg
     1321 catcaggctt caaccacttc gaagttttgt tctcggtaaa ttcttgttct gctccctcgg
     1381 ttgcccgtcc gtaaaaaagg agaacatgcc atttcagatg actaaaaata tgagtaactt
     1441 ctcctaaatg tcgtgtctgc caaacaaaga gttcctgctt ttcaaatggg agattttgct
     1501 cttcttctgc tactaggtca tcaaacagat cgatttctgg ctttgtttcc cattcttttt
     1561 tcaatcgctc atactcctct tgtgtcactt ccatcattgg aaatgtccac atattcgcca
     1621 gcaatttttg gctatctctt tcttcaaaat aatacgctcc agaatgattt tgaagagctg
     1681 cactgatata ataaacgtct tttggctttg ctttttttgt ttttacagga aaactcgttt
     1741 ggattcctcg tttgttagct aaacaaaagg cttggatcgg acaagtctca cactttggag
     1801 aagttggtgt acagatagct gaacctagat ccatcattgc ttggttgaat tcacctggat
     1861 gcttttcatc aatgattttc cgcatcgctt catcaaagat tttcctgcta gaagcttttg
     1921 cgatgtctgc ttcaatgcaa aacaatctgc tgactactcg catcacgttg ccgtcaactg
     1981 caggttctgg aagtccaaat gcgatacttg caatcgcgcc tgtcgtatat ggtcctattc
     2041 ccttcaatga gctaatttct tcaggcgttt gcggcatttc cccatcaaat tctgacatga
     2101 tctgtttagc agcagcttgg atgttccggg ctcttgagta ataaccaagg ccctcccatg
     2161 cttttaaaag cttttcttct ggagcatttg ctagctcttc aattgtagga aaccattcca
     2221 tgaaacgata aaaataatcg atcactgtgt ctactctggt ttgctgaagc atgatctcag
     2281 agatccagat acgataagga tcacgattat agcgccaagg caggtttctt ttttcttgtt
     2341 cataccattg aatgaactga tcttgaaatt cttttgtttc tttatctgtc catttttccc
     2401 attctttatt cactttcctc ttccttttcc gtaatgaatc gctggatcat atccaaatca
     2461 aatccttttt gatataagct ttgctttact tttagatttc tttttttagg ttcaaacctt
     2521 aaatttcttc gccatagttt atctccttgt ttgactaaat aatcatattc tatttcttga
     2581 tctgcttctt gcggaagatc agctatcgct tgttggatca cttcttgaga aaagcctttc
     2641 gtcatcaatg tttgttggat ttttctcaat aattcttttt ggctttttcc gtgatttttt
     2701 ccaaacgctt tttcggctgt ctgatgtgca ttttgaactt ggtcttcaaa tgtatattgg
     2761 ctgagcgctt gttcaatgat ttcaggtttc aaaccttttt gctgcatctg ctgcgctaat
     2821 ttctttggtc ctttgtcact taagcgcata ttcgtgcgca cataactttc cccatagacc
     2881 aaatcatcga caaggtccaa ttcttttaag cgggctacga ttttatttcg atcttcttga
     2941 aggatttcct tttcttttaa gtatgttcgg atttcttttt ccgatcgcaa ctgataactt
     3001 aagtaattca ttgctaggtg aaaaccgaaa tcagctccgc tactcttctt gatctcttgg
     3061 atagtttctt cgtctaattc ccgtcctttt aataatcgat agcgtactaa tacatcttca
     3121 gatacttgta aagcttctcc ttcagataaa tctacgcgat agaaagggcc tttgccttta
     3181 ctgattctcg taacggttaa cataaacatc ctcctcgaac atatattctc tatcatacca
     3241 cagaaaatcc ccgtaatcag gtattatatg ttagaataaa ccacagaaaa aagaaaaagg
     3301 gagatactta tggcagaaac aattgtcaaa actggacaaa cggttccttt gaaaatcaag
     3361 cgtttaggca taaatggtga aggaatcggt tatttcaaac ggttgatcat atttgttcca
     3421 tatgcactac caaaagaaga agtactagtg aaaatcacga aagcaactcc tcgctatgca
     3481 gaaggagaat taataaaagt caaaaaaaca agcaaagatc gcgtagtggc accatgtcct
     3541 gtttactatg aatgcggtgg ctgtcaatta caacacttag cttatcaagc tcaattggat
     3601 tttaaaaagg atctgctttt gcaagcattg gaaaaattca aaccagcagg ctttcgatct
     3661 tatcaacttt tgccgacgat cgggatggat gagccttggc attatagaaa caaagcacaa
     3721 tttcagttac gaaaaaataa gcagactcaa aaaattgaag ctggtttata cgaagcaaac
     3781 tctcatcagt tagtccctat aacagactgc ttggttcaag aacctcgaac acaaaaagta
     3841 atgaatactg ttgttcaact attgaataaa tttgatgcac ccatctatga tgaacggaca
     3901 aacagtggaa tcttccgcac aatcatggtt agaatcggtg ttaaaactgg ggagttacaa
     3961 gttgttttta ttactcgcag taaaaaattc ccgcaaaaaa acgcaatgat ccgtgagatc
     4021 aatgaacgac tgcccgaagt tgtttcaatc atgcaaaatg tccaggcaca aaaaacgtct
     4081 ctcgtgatgg gggatgaaac gatccactta tggggaaaag aagccattga agaacaaatc
     4141 aatgaagtga ctttcgatct ttctcctcgt gccttctttc aactcaatcc tcagcagacc
     4201 gaattgcttt atggcgaagg aatcaaagca ttagatgtcc agcctaatga aacgatcgtg
     4261 gatgcttatt gcggagttgg gacgatcggc ttaagtgtag caaaacaagc caaagaagta
     4321 cggggaatgg ataccgttcc tcaagcaatc gctgatgcaa aaaaaaatgc ggaaagatta
     4381 ggatatcaca acactcgata tgaagtcggg acagcagagc aagttctgcc taaatggttg
     4441 aatgaaggtt ttcagcctga tggtatcatc gtagatccac cacgtacggg tttggataac
     4501 gcattgatcc aatcattatt gaaataccct ccaaaaaaac ttgtttatat ctcctgtaat
     4561 gtttctacac ttgccagaga tctggttaat ttaagtaaaa agttcaagat tgaatattta
     4621 cagtccgtcg acatgtttcc tcagactgca cgttgtgaag ttgtcgtgaa gatgacgaga
     4681 ctcgctgact aaatgaaaga ggttgtgaaa aagtctgccc tgtatcaagt aataagaaca
     4741 gccaaacaaa aatagctctt catgttttat gaatactgta cttgtgaccg aagagttaac
     4801 aggaggacac tatttattta aaaaaagggt tgtgacatag tttttgtcac agcccttttt
     4861 gattattatt ggatattcac gtctatcact tgataaaatg catttgtcgt atcgctgata
     4921 ttccatactg ctaaaatcac attatatcct tttcgatcct gcggaagtgt gatcgtttgg
     4981 ttgactgttt ttggtggaac agttgctttg tcgtctattt ttgtgatcaa ttcaaaatca
     5041 ctaaatttca aaggttgatt aggattccaa gttggtttgg taatgtagta atcccaagta
     5101 cttgtccgat gttgtgctgt taaattccaa gtaatattta atgttcctgg attaaccatg
     5161 tttttatgcc atctgttaga tgtctgttca tctaaaggct caaagccgct gactcctgca
     5221 ctagcaattt ttccatcaat gaatgtattt ttggtagctt cgatactttg cggttcccat
     5281 tgtgctcttc cgacattttg atttaagttt cctgctgctg atgttcctag gtatgcacgg
     5341 cttcctggag aagtaatata accatgcgca aaacctggaa tgctaaaacc gaacaaccct
     5401 aaactaacta acccaataaa caataacgta ctaatctttt tcatgtagaa acctccttca
     5461 tttgataacc acattgtaaa cgctttattg tattaacaca aacattatgc ttttataatt
     5521 ttatgttgaa gtaaaaaagg tgaaaaaagt aagatgcaga ttataacaga agtagacgag
     5581 aaaagtacaa atagaaaaca tgagaatcaa atcatatgat ctttttcaaa aacatcattc
     5641 atataaacaa atgttcaact ttttaataac aacaattatc aatttttttc ttacttcaca
     5701 aactaaatac aggtcttgct gtgagccttc atggtaaact aatattatag aaaggagtta
     5761 gtaaaatgaa gatgataaaa gatattcgtt tttgggtttg tgttatagga attgtcatat
     5821 taggcttttt atcagggttg cttagcggaa atcccggaaa atattactat tctttgcaac
     5881 ttccaccatt tgcaccacct agctggatat ttgggccgat gtggacctta ctgtatatat
     5941 tgatgggtat ttctctttat ttgttactta atcacaacaa caaaaaacag cgaaacaatc
     6001 ttgtcggtct ttttgtgatt cagttcattt ttaattttat atggtctgct ctatttttta
     6061 atttaagaaa tattttcatt gcagcaatcg atattacact tttagttatt ttcttgtcag
     6121 tgcttatgta tcagttgtgg ctgcatcatc gcctggcaat gtggctcatg attccttatt
     6181 atttatgggt actattcgca actctattga attattcaat ttatttttta aactaagcgc
     6241 taaaaagaga cgtcctgtaa tttaacacat agaaaaagtg ccacctaagt tagatttttt
     6301 gtctaattta ggtggcactc tttattaacc aaactatttt tttctagtac ccacttgttg
     6361 ttccatactc attattctgg tcataaccat aaccattttg ttcctgtcca gcgtaaggat
     6421 cataactttg agtatcttga cttggtgtat agtactgact tgtatcttct gtttgctgat
     6481 aataggtatt cggatcttgg tactgatcat atgtgttttc tgaataggaa gaataatcgg
     6541 tgtacccttc actattcgat ccatcaccgt ttgtcgaatc gccatcttcc gaatcatcaa
     6601 agaacatcat tgaagcattc tcatttttca aattaggtaa tgtatcgctt gtttttatat
     6661 ttaattgttt cttcagttca ttttggatcg aaagaagatc attttttcct aaaatttgat
     6721 agtagatatc attgatcatt tgtccttcgc cttgcaactg gtcttgtttg attgtttcaa
     6781 acgccggggt gtagttcgtc gctacatcaa gcatgtcatc ccaatctaag tccgtcgtca
     6841 cattgttctc aactgctttt aaaatttttc tataattgct tacgccatct aaacttaaaa
     6901 ctttattgac gattttcgtc actacttccc gctgacgacg ttgtcgaccg atatcgcctt
     6961 ctggatcttc gtgtcgcatt cgagaatagg ctaaaccttt ttctccattc aatgtttgtt
     7021 cacctactgg tacatggaca ccatccaaag taaagtcaat tttattattc actttgatgc
     7081 caccgaccgc attgatcaaa tcttccatgc catccaaatt gatcgttaca taatgatcaa
     7141 taggaatatc gagcagttgc tcaattgaat ccatggccat ttcgacacca ccaaatgcgt
     7201 aggcatgatt taatttatct accgttccat aacctacgat attcgtataa atatctcggt
     7261 ccaaactgat gatcgttgat tttttttgtt tcggattaac tgttactacc atcatcgtat
     7321 cagaacgtcc ttgttccgtt cttcctaatc caccggtatc taaacctaat agcaaaaccg
     7381 aaaaaggttc tttgtcatca atgcttactc tctcagaacg tttggaggat attcgattag
     7441 agtttttaga aattttgttt actgtttggc tcgcttctcc cataaatctg attccgtatg
     7501 ctgataatcc ggcaatcagc aaaacgaata cccctaacaa ggttaataga actttttgcc
     7561 atcgcttcat aatacacctc tgtttcacat tttctaaaat attgtctcat ataactgttc
     7621 aatcagcaaa ttcacttttt aatcataaga aaactttaaa aaacattttt gtgtaacgat
     7681 tattattttt taaaatttct caaaattctt aactatcata ccataccgtg aaaaagatcg
     7741 aaagaccgaa tacacgcagt tcgcaatcgt tttatctttt tttatgtatt ttttccagaa
     7801 aaagcgaaca acaaggtatt ttccaaataa tcgtgcagta aaatgatcgc acataccttt
     7861 cccatctttt taacagtctt tgcctaccgt tcagattatc attcgatttc acgacaattt
     7921 cttcctatga ctggtccttt tgttaaaccc atcttctatt cgttttattt ccagctcact
     7981 gcatggctct taaaatgact cgaactagtg attgcattac catcatcttt taatggatag
     8041 atatgctcct cttcaaagta aaacgatttt cttttaaagt aatagaattg acatggtaat
     8101 gagtatgtat actagtggtt tcacaaatgg tcttttattc aacatccaaa aactgaaatt
     8161 tctttaaaat ccattactaa cgaagaaaat gttccttgct tgataattag ttaggacatg
     8221 tcaagtgaac aaatgcattt acttagccaa aaaatctaaa aacttcataa atagacaaaa
     8281 agacacgact ctctaagaag tcgtgtcttt attcaacaaa ttattataat ttagtcactt
     8341 cagcagcttg aggtccgcgt gcaccttcaa caatcgtgaa ttctacttct tgaccttctt
     8401 ctaggctctt gaagccgtct ccttgaattg ctgagaaatg aacaaatacg tcatctccgc
     8461 cgtctactgt aataaaccca aatccttttt cattgttgaa ccatttaacc gttccgtgtt
     8521 ccataaatgt atatcctcca aaaaagttct tgcaagtaac cttgcaagaa cattataccc
     8581 aatttagaaa acgctagcaa gctttcgctc ttttattttc caaattattt ttaagactga
     8641 tatgacggag gaaatggtta ttttgctgct tcgaaacgtt tgtttacttc atcccaatta
     8701 ataacattcc agaatgctgc aatataatct ggtcggacat ttttatattt caaataataa
     8761 gcatgttccc aaacgtccaa acctagaatt ggtgtctttc cttccatcaa tggagaatct
     8821 tgatttgcag tagaggtaat agctaatttt ccattttcca ttacaagcca agcccatcca
     8881 gaaccaaatc gtccagcggc tgcttttttg aattcttctt taaaagaaga aaaatcacca
     8941 aaagcttcat taatcgcttc ttttatttct cctgtaggtt cgccaccagc atttggtgcc
     9001 atgatttccc agaaaaatga atggttagca tgtccgccac cattgttacg tacagctgtc
     9061 ttgatatctg ttggaatagc gtccatatca gataataatt cttctattgt tttttcgcct
     9121 aattctgggt atttctcaat tgctgaattt aaattcgtca cataagtatt gtgatgctta
     9181 tcatgatgca gatgcatcgt ttcttcgtca atataaggtt ccaatgcgtc atatgcataa
     9241 ggtagatctg gtaatgtgta agtcataaaa aaattcctcc tcaatgtttt cttaataatg
     9301 tctacattac aaagagtaac aaagagaagg aaattcttca attgttatgc ctagtcgtct
     9361 ttttcacttt gacctacttc ttcttcaaaa acctcagttt ctttaaaaat aaacaacttg
     9421 ctgaaaatat agttcgcaag gataacaata atttgagtga tgattttcgc cacatactca
     9481 ttgctgttca taacattgat caacaatacc attgccccca tgtccaatcc gtaagaaagg
     9541 atacggtaga agaagaactt accgcattca ataagtgcat gtgtaaaatt cggtgatttt
     9601 gaatggaata cccaaagttt gttcgttaca aaagcaaaca atacagaaca aaaccacgaa
     9661 atagaattgg ataaggccat acttaaatca aaatattggc gtgcgagagc aaaactaaca
     9721 aaatttacaa tcgtagccaa accaccaaaa aagagataga ctagtatctc ccaatatcct
     9781 tttgcttcta aatatccttt taactgtcga tactgcttca tgagccaacc taccttatta
     9841 aaaattctta tttatcatac tctatatttc aataactttc atctttattt aaaaaaatta
     9901 attttttttg atcctttgcc tttgtctctg cttggatcgt cacatgtgta ataccatatt
     9961 ttaattttaa taaagaaatt atacgaggat atatcttttc aatctcgctt agtagctgat
    10021 cttcaaaatc aatatgtccg tcgaaaataa ttatcttttc gctatactgc caaatatgga
    10081 catgatgaac atcctttacc ccatcgattg cttcaatttc ttgttccatt ttttcatagt
    10141 cgatagcagg tgcactttgt atcaaaatag cggcagcttt tttgatcacc attatcgctt
    10201 ctatcaatat atatatcgaa atgatcagtg taataactgg atcgatccag tagatatcga
    10261 aaaaacggat caaaattgct ccgataatca cacttaccga agacagtgta tcacttaaca
    10321 aatgcaaata actagatttt atattcaaac tttcatctgc ttcttgtcgt aataataata
    10381 ctgagaacaa attcgcgagc aatccaataa ctgctactgt tagcatcaaa tgactattta
    10441 tcttttctgg tgaagtgaac cgcttgaatg cttcaacggt taaaaacaag gataatatga
    10501 tcaatatgaa tgagttgatg aaagcactca atatttctaa acgctggtag ccatacgtac
    10561 gttttttatt tgcttctttt cgggccattt tttgtgcccc gtaagaaaaa ataattgcca
    10621 atgtatcact aaggttatgg aaagcatctg aaacaagaga caaactccct gacataatcc
    10681 ctccaataaa ttctgataaa gtgatcaccg cattcaaaac cactactcca aatagttttt
    10741 ttgatgatct ctgtggctgt gtaggcacta ttccttcctc cattttattt atattggata
    10801 gtctttagac aagaataaca tttttttgat atttcaccaa tcattcagct gtttccttaa
    10861 agcacttgta tttcacttga tacttcgcta gaattgcaag tgatgacact actagatgag
    10921 gagtacttat gacaacaaaa caattaatta tcagttcctt tatacgattc aaagacctaa
    10981 aggaggcgag aaatgtccca ttttggaaag ccattgtcta tcttttagtt ttgagtataa
    11041 ttatggcttt gccaatctct tttcaagttt ttcaagtctt aaacaacatt caattggatg
    11101 ggcaaaagat tgctactcgc attcctgatt ttacaatcca aaacgggcag cttcaaaccg
    11161 aagaaaaaga aggattcatt taccaaacaa actccattat cttcacattt gatccagagg
    11221 gaaaacgaac agaacaggac atctctactg atttgatggg gaattttgtt agtgtcggga
    11281 tgttaaaaaa caaacttatc atagctcttc ctaatacagg cacgacttct gctttgttga
    11341 acaataacca attagaactt ccctacacca atgaatcttt aaaaaactta acaggtaagc
    11401 agctccgttc ttttttaagt gaagcatcta taccactttg gataaaagtc ctgacattta
    11461 tattttctat ttatcctagt tttctgaatc tgctgatcac tttgctattt accaacattg
    11521 ctgcttttct ctatgcacgc tttcgactaa caaaagctac ttttcttgat tgtttaaaaa
    11581 cattgatcta ttcaatttca ttgcctacta taattgcaac aatcttgatg gtctttcttc
    11641 cttcttttga cactagcgcc ttcattgctt ttgcaggaat ctttattttt gctcaagctg
    11701 tcaaaggatg ggcaaaaata tcgatcaatt aagaaataaa gacaactcgt tatttctact
    11761 tcaatagacc cttttagagg ttgtgacatt tttttgtcac agcccctttt ttatttgaaa
    11821 aatatttctt tctcaaaaaa caagcaaggc gcttcaaagt tcttcttgta tgcgctacac
    11881 ttagagtaaa gaaaggcggg aaattaacta tgtcagaaag aatcatttat gcagatcgtc
    11941 catttcgtga tgaatttatc gaagaaatcc atactatagc gcctggttat atctttaaaa
    12001 cagaattaca accagaggat ctacaaaatg tagagatcag tttgggctgg aactcagact
    12061 accaagaaaa actattagcc tcttctacct tgaaatgggt ccaatctatc tcagctggtg
    12121 ttgatcagct accccttgag actttttcaa agaaacatat tttactttca aatggtagtg
    12181 gcatccacag tgaatcgatt acggagcatg tcttaggaat catccttggg tattctcgtg
    12241 gtctttttca agcacaaaag gcacagagtg acatgaaatg gttaggttca tcggtccatt
    12301 accaatctat ccaagggaaa aaaatactaa tcattggaac tggccatatt ggaaaaatga
    12361 ttgcaaaaaa atgcaaagca ttagacatga actgctatgg aatcaataca tccggtcatc
    12421 cagcagaagg aatggaaaag actttttctt taaatcaact aaaggaagtt cttcctgaag
    12481 tagatttcgt agtcaatatc ttacctctaa cggaggaaac aactgggctc tttgatcagc
    12541 atatgtttga acactttgat ccaaaatctg tattcatcaa tgttggccgt ggtgcttctg
    12601 ttaagacaca agatctggtg caggctttaa ataaccagca actttccttt gcagcattag
    12661 acgtttttga ggaagagcct cttccacaag atcatcctct ttggaaaatg gacaatgtac
    12721 tgattacttc ccacattgca ggtttgacac ctgattttca aaagaaatta atggctattt
    12781 ttttaaccaa tctgaaaagc tactttgcca cccatgagct tcaaaccaat caagtaaaat
    12841 tgtctgcagg atattaatag ctgaaaacaa tattttcaaa agaaaaaaga gaaggtgaca
    12901 aaaattgtgt caccctctct ttttttattg ttttttaaag tgataggttg gctcctccag
    12961 gttgggatca taatcaacaa gtaaatcata tcctttaaag aaccattcat ctgcttcctc
    13021 gataaaaaaa agtgtcccat caatttccac tttctttaca ggatgttctg gctgttcaac
    13081 tgacattcca atcgaaaaac catcatgaac ctctgttttg ccgtagactt ttccaaaaaa
    13141 acgtattccg taagtttctg gcagatcaat ttctgagtca aaccactttt gtgcttttgg
    13201 cgttaccgtt aatttcatcc caacaaccta ctttctcttt tctttctatt gattcatctt
    13261 atcgtctaga atatccacat cgcctgtctc tccaataacc agtagattat cattttcacg
    13321 aacatattca tctgctgcag gagaagcgat aaccgtttga tctactcttc gtatggcgac
    13381 tactgttaag tcaaaacgtt gcctgaaatt taattcagct aatgttttgt tgaaaaattt
    13441 aggattggag actcggattt ctgctaaaga atatttatct gacaactcta ggtaatctaa
    13501 aatattcttt gacactaaat tatgcgcaat ccttattccc atgtctcgct cgggatggac
    13561 gacgcgatca gctccgatct tttcaagtac tctggcatga tactcatttt gggcttttgc
    13621 taaaatattt ggtacgccca tttcctttac catcagagta actaagatac tggcttgaat
    13681 atcttctcca atagcgacaa ttacatgatc gaaatttctt atgcctaatg atcgaagtgt
    13741 catttcatcc tgtgcatttg ccacaacagc atgagtggct atattcatat attcattgac
    13801 ccgatcttca ttactatcaa tagccagtac ttcttgacca gcttcgatca gtgttcggca
    13861 gatacttccg ccaaatcgtc caagacctac aattgcaaaa ttttgtttca ccgttttcct
    13921 cctttagtat cttcttttct cagtataaca aagcctttac aaaaacaaaa gcaagcatca
    13981 ttattgtaaa aaagccaaga aaaataatag ttattttctc agcttttgat tatcctcttt
    14041 atcatcgttt ttatttcacc aaaccatgtt tgaatgcata gatagcggct tgtgtacggt
    14101 cttccacttc tagcttagcc aatatattgg aaacatgtgt ttttactgtt ttcagtgtaa
    14161 taaacaattc gtccgctatt tcctgattac tttttccttc agaaatcagc attaaaattt
    14221 cattttcccg attcgttagt tcttcatgta atacaggctc atttcgccga ctcatttttt
    14281 ccatcatttt tgttgtcact tctggttcta atactcgctc gccacgttgc gttgccctta
    14341 tagcatcagc aatttcatgt gcggtagagg tcttcaacaa ataccctgct gcacctgctt
    14401 caatggcagg ataaactttt tcgtcatcaa taaaactggt tacgataatg attttagctt
    14461 ctggccaatc ttttaagatt gcttttgttg attcgatacc atccatttct tccatgacta
    14521 agtccattaa aatgacgtcc ggtcgaagtg tcatcgcctt ctcatagcct tgtcgtccat
    14581 tttcagcttc tccaattact tcaatgtctt cttgaataga taaataaaaa gagacgccta
    14641 agcgcaccat ttcatggtca tctactaata aaacttttat catccttatc tatgcctcct
    14701 tcatcaaagg gaccttgatt tctacacttg taccttgacc tttaaaacta atgattttta
    14761 ctgttccacc aataccagct actcgttctt tgatattgtt caatccataa cttcccgttt
    14821 tcgtttcatt catattaaac cctgttccgt cgtcaataat acgtaacaaa agattattgt
    14881 ctattttgtg caaatatacc tctaattcat tggctttagc atgtcttaat gtatttgata
    14941 acaattcttg aacgattcgg aacaagtgat cctcaatgga actagatagt tttacatctt
    15001 ctacatccca tttcagcgaa atctggattt tattttgcaa ttccttcaat aactgctcga
    15061 taccttgctt taaacttttc tcttctaaat tgactggacg tagatgaaga agcagcgcac
    15121 gcatctcaga ctgggaagcg ttgatgatct ctgctaccat tttcaactgc ttgcgaaaca
    15181 tttctggtgt ctcgcttttt tctgcttgct ccgtcaatgc cgacatcatc atcattgctg
    15241 caaacaattg ttgcgaaact gaatcatgca gctcacgggc taatcgatgt ctttctaatt
    15301 ctaaaatttc ttctttggtt tgtccatcta catattgggg acggctcgtt acaatttgta
    15361 attcactaga tacttcaatc attttttctt ttatcttagt gatttcctta tcaatatctt
    15421 tgatgtataa atcgtccgat gcacttggga tcggaagaag caacaatttg gattcataat
    15481 tgccagaaga aagtgcacgc agcttttctt cgattttccc gtattttgtc ttttgaataa
    15541 gtgataataa tagaaagaca attaatccta cacctaagga aatggctaac aaatggaaga
    15601 taagcggaac atataataaa cgtgcacgca gtaattctcc ccaccaatga ctttgattgc
    15661 tggcataaaa ataagtgaaa agtgaaaata gaataataag gaaagccgca atccccgaat
    15721 aaacagctag catcgctctg gatatttttc ccatcatatt cgtatcacct cgacatctcc
    15781 aatcaaggta ttagtaataa tcttcaatct acgagggttt tcatcataat cactgctgta
    15841 gattttgatt tgttcatttt tcaaagaaaa ttgctcttct tcaaacaaga catttcctac
    15901 taatgtcgca tgctctaatc ggatggctac gcccaaaggt actaagatcc gtgttctgcc
    15961 tatccctttt cttacaatca caatattatc atcttttggc aaaagcgtat tgcccaaatc
    16021 tatgatagta tcaccagaaa tgacggcgat gttgatatcg tcccattcat agacgtcgtt
    16081 tccaatacgt tggttaccga ataattgctg tcttttccgc tcattattat gtgtttttaa
    16141 ttgctctgtt tggatcatca tgatctgttt ctttcgccaa aaagcatttt tggttaaatc
    16201 tatccctgaa atctctacac ctttcagacc aataaataaa acggcaaata cagccatcat
    16261 ccataaagca ggactgttga ctaagctaaa aaaaatgacc aaacttccta atatcaattg
    16321 aaaattttga aatttagtac gaggatgttt gcgcatagct agatatatat tgaaaatacc
    16381 gaatatcact aaaagcaaaa gtccagtatt gtttacgatt tgccaaacag caaataacag
    16441 cagtagtgct tcaactacca caaaaaaacg ccaagaacta ttcatcgctc tttctccctc
    16501 ctgacacatt ctcatttcat catacctatt tttttaactg ttggctatag gactttagat
    16561 gtaagatcgt ttgttgaaat ctaaaataca caaagagaaa aagatctaga gtgtatcatc
    16621 agtaagatga actctctaga tctttcagtc agactacgct tgttctactt tgacgatttt
    16681 aactaacata tcgccacctg gagtagcaat agttacttca tcatttttac gtttgccaat
    16741 caatgcttgc gcaataggag aatcattgga aattttgcca gaaaacggat ctgcttcagc
    16801 gcttccgaca atcgtgtact cttcttcttc tccatctggt agttcgatga atgtaactgt
    16861 tttaccaatt gatacctcat ctgcatctac accgtcgtta tcgatgattt gagcaaaacg
    16921 aatcatattt tcaattgttg tgattcttcc ttcaacaaat gcttgttcat ctttcgctga
    16981 ttcatattca gagttttcgg aaagatctcc gaaaccgcgg gcaattttga ttcgttcaat
    17041 gatttctccg cgtttgactg tttttagttc ttctaattct ttttctaatt tttctttacc
    17101 ttctagagtc attggataaa ctttctctac catgtgtaac gtctcctttt ttcgataaaa
    17161 taccgcaaaa ggtaatcttt tgaggaatat agtccaaaaa agattaccac gcttttcttc
    17221 aaatgtaaat gtttttctaa aaatgatcaa tgtctagagc ctgtttttct aagaattatt
    17281 tacatatttt tccactaatt ccatatgttc ttcataagtt ttagcgaaat aaacatttcc
    17341 agtgctcgta tctgctacga aataataata gtcattttct gctggttcta atactgcctt
    17401 gattgcctct tcgcttggat tgtcaaaagg tccaggtcca tagccggtat tggtatacaa
    17461 attatatggt gaatctacag ctgtatcttc atacgtcact aattctttgt gttcacctaa
    17521 tgcgtataaa acagagatat ctgactgaag tggcatattt gctttgattc ggttaaagaa
    17581 gacttgtgca atgtttttac gatcattttc ttttacgcct tctttttcaa ctagagaagc
    17641 tagagttaaa acttcttgta cagtcaaatt tttctgcttg atagctgaat aatagttttg
    17701 catgaccgta ttcgtcttgt tcaccatttc aatcactaga tccttaagcg aagtactcgt
    17761 gtaataatca tatgtggctg ggaataagta accttccaaa cggtattttg tgttctcagc
    17821 tttagatgca ctttccaaca gttctgggaa tttttggtgc aactcgttaa agaaagtctc
    17881 atcattcact aaatctaaaa attctttctt gtctttacca gttaccttcg ctacccgttc
    17941 agcaatctga tcgatatcgt acccttctgg aatggcaatt ttcccatctg caacttttgt
    18001 tggctcagaa gtaccgcctt cttgcaactg tttgccaatc tcgtcaagag tcatattagg
    18061 cgctaactga taatagccag cttgaaagcc agttaaattt ttaaattttg tataataatt
    18121 gaaaacaatc ccgcttttaa taatattgtc cttctccaaa atctcaccaa tctgcttgtt
    18181 agaagagcca ctcgggatct cgacttggac taattggtca tctgatttat ctaaaggctt
    18241 caacccgcta tctacataac gatacacggt aaatccaaga aatccgccaa taatcaataa
    18301 tgtaagagca atcactaaaa tgatcttcct cacaatctta tcttcttttt tacgcagatt
    18361 tctccgcttg tcgattatat ctgctgtagc tgccttactg gcttcttttt tatctttact
    18421 tgggtgttgt ttgtttcctg acaaaacaac tcctccttac tatcaagttc gtaactttat
    18481 tcattataca tgatatttga attggcgtga atgattttat ttaaatattc tatcaaaaat
    18541 gtaagta
//
LOCUS       DAFLWQ010000054        18504 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.055, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000054 DAFLWQ010000000
VERSION     DAFLWQ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.055"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            99..746
                     /locus_tag="L1V16_001881"
     CDS             99..746
                     /locus_tag="L1V16_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBN1276221.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    875..1091
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1139..3784
                     /locus_tag="L1V16_001882"
     CDS             1139..3784
                     /locus_tag="L1V16_001882"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBN1276222.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            4094..5407
                     /locus_tag="L1V16_001883"
     CDS             4094..5407
                     /locus_tag="L1V16_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBN1276223.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            5397..6050
                     /locus_tag="L1V16_001884"
     CDS             5397..6050
                     /locus_tag="L1V16_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBN1276224.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            6105..6797
                     /gene="radC"
                     /locus_tag="L1V16_001885"
     CDS             6105..6797
                     /gene="radC"
                     /locus_tag="L1V16_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBN1276225.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            6947..7147
                     /locus_tag="L1V16_001886"
     CDS             6947..7147
                     /locus_tag="L1V16_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBN1276226.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(7401..9080)
                     /locus_tag="L1V16_001887"
     CDS             complement(7401..9080)
                     /locus_tag="L1V16_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBN1276227.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(9082..9294)
                     /locus_tag="L1V16_001888"
     CDS             complement(9082..9294)
                     /locus_tag="L1V16_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HBN1276228.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9687..11417
                     /gene="efrA"
                     /locus_tag="L1V16_001889"
     CDS             9687..11417
                     /gene="efrA"
                     /locus_tag="L1V16_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HBN1276229.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            11414..13174
                     /gene="efrB"
                     /locus_tag="L1V16_001890"
     CDS             11414..13174
                     /gene="efrB"
                     /locus_tag="L1V16_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HBN1276230.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            13269..13466
                     /locus_tag="L1V16_001891"
     CDS             13269..13466
                     /locus_tag="L1V16_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276231.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            13619..14104
                     /locus_tag="L1V16_001892"
     CDS             13619..14104
                     /locus_tag="L1V16_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBN1276232.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(14208..14801)
                     /gene="clpP"
                     /locus_tag="L1V16_001893"
     CDS             complement(14208..14801)
                     /gene="clpP"
                     /locus_tag="L1V16_001893"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBN1276233.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            14981..15508
                     /locus_tag="L1V16_001894"
     CDS             14981..15508
                     /locus_tag="L1V16_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276234.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            15599..16336
                     /locus_tag="L1V16_001895"
     CDS             15599..16336
                     /locus_tag="L1V16_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBN1276235.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            16340..17257
                     /gene="miaA"
                     /locus_tag="L1V16_001896"
     CDS             16340..17257
                     /gene="miaA"
                     /locus_tag="L1V16_001896"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBN1276236.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            17259..18488
                     /gene="hflX"
                     /locus_tag="L1V16_001897"
     CDS             17259..18488
                     /gene="hflX"
                     /locus_tag="L1V16_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBN1276237.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT         5984 a         3200 c         4022 g         5298 t
ORIGIN      
        1 atttgtctca cacccttttc cttcctactt gtaaccttgc tcccgtgtta gaaacatgtt
       61 acactaaata tgtgaaatta ttaacaagga gcgtcgttat gcgagaaaaa acagatacac
      121 tgccaaaagc aactgcgaaa agattacctt tatatttacg ctacttgaag atgctggatg
      181 actcaggtat aagtagaatc aaatcaaatg agttcagcga aatcacccaa attccttctg
      241 caacgatccg cagagacttc tcgcaattag gcgagctagg cagaagcgga tatggctatg
      301 atgtcccttt tcttatcgat gtattcaata atatccttaa tactaaagaa gaaaaacgaa
      361 tcgcattagt aggatatgga aatcttggca aagcattgaa acacaacaat tttagaagaa
      421 atgaaaatct aaatatcgtg tgcgtctttg ataatgatcc agcactgatc aatcgagtaa
      481 ttgatggaga aatgatctat ccgattgatc gtttcgcgga gatagccaaa gcaaaaaatg
      541 tgacagtagc aatctctacg gtaccaagta aatattcaca atctgctatt gatgaaattg
      601 tcaaaggaaa tgtaaccgct atacttaatt ttgcgcctga cagagtaact gtcccagctt
      661 atgtcaatgt tcaatacatt gatttgacaa ccgagttgca gacgcttatt tactttgatg
      721 agaattactc agaagttttt tcttaggaaa atttgagtag gcttattgat cttgcgagaa
      781 ctcgtcgtaa ttctttcaaa aattttttag tactaaatga agtggttttt tcacgaccac
      841 ttgttgacta aaaaaaaaaa ccattgtaga atgaagcata acgctgaaca agaggagtaa
      901 ctggcacatt cattcttaga gagagaacta tctgctgaaa ggttctcaat gacaaccagt
      961 gaaggtagct tgggagtttc tgtcttgaat ggagtagaga tagacgagtc gtgatcgtta
     1021 actcacttga gaggcaataa tgattgatta ttgcaattta ggtggtaccg cgtaaatcat
     1081 acgtcctaga atacgaaagt attttaggac gttttttagt ttaaaggagg aaaacagcat
     1141 gacggaagaa aataacctat caacaaaata taatccgcaa gaagttgaag ctggacgtta
     1201 tcagcattgg ttagaacaag atttgtttaa accgagcgga gataaaaaag caaaacctta
     1261 ttcaatcgta atcccgcccc caaatgttac tggaaaactt catttagggc atgcttggga
     1321 tacgaccttg caagatatgc tgattcgtca aaagagaatg caaggatatg atactttatg
     1381 gctgcctggt atggaccatg caggaatcgc gacacaagca aaagtagaag cgaagcttag
     1441 agagcaaggg atttctcgtt atgatctagg tcgtgaaaag ttcatcgatc aagtgtggga
     1501 atggaaagaa gagtatgcga gccacatccg cgaacagtgg gctaaaatgg gcttatcttt
     1561 agattacagt agggaacgtt ttacattaga tgatggatta tctgaagcag tacgtaaagt
     1621 ttttgttacc ttatacgaaa aaggtttgat ttatcgtggt gaatatatca tcaactggga
     1681 tcctcaagca cgaacagctc tatctgatat cgaagttatt cataaagata tcgaaggcgc
     1741 cttttatcat atgagctatg aactagcaga tggatcaggc gtagtagaaa ttgcgacaac
     1801 ccgtccagaa acgatgttgg gagatacggc gattgctgtt catccagaag acgagcgtta
     1861 tcaagcgctc atcggcaaaa aagtgattct acctttagtc aataaacaaa tcccaatcat
     1921 tgcagatgaa tatgtagata tggaattcgg gacaggtgta gtaaaaatca ctccagcaca
     1981 tgatccaaac gactttgagg taggtaatcg tcatgatctt ccacgcgtaa atgttatgga
     2041 tgatgatggt acgatgaatg aactagcagg aaaatatgct ggaatggaac gttttgctgc
     2101 tcgtaaagca atcgtgcaag atctgaaaga aatcggtcga ttgattaaaa tcgatacgat
     2161 gatccacagt gtgggtcatt ccgagcggac aggtgtcgtt gttgaacctc ggctgtctac
     2221 tcaatggttt gtaaaaatgg cgccgttagc gaaaaaagcc attgataacc aagaaacaga
     2281 tcaagcagtg gaattcttcc ctccaagatt caatcaaacg tttttacgtt ggatggaaaa
     2341 tgtccatgat tgggtaatct cacgacaatt atggtgggga catcaaattc ctgcatggta
     2401 tcacaaagaa acaggtgaaa tgtatgtagg gatggaagca ccagcggata gtgaaaactg
     2461 ggtacaagat cctgatgttt tagacacttg gtttagttca gctttgtggc ctttctcaac
     2521 aatgggctgg ccagatacgg aaagcgaaga ttataagcga tacttcccta ctagcacttt
     2581 agtaaccggt tatgacatca ttttcttctg ggtaagcaga atgattttcc aaagcttgga
     2641 atttactggc gaacgtccat ttgagaatgt cttgattcat ggattgattc gtgacgaaca
     2701 agggcggaag atgagtaaat cattaggtaa tggaatcgat ccgatggaag taatcgaaaa
     2761 gtatggagca gatgctctcc gctggttctt atcgaatggt tctgcaccag gacaagatgt
     2821 ccgcttcagc tatgaaaaaa tggatgcttc ttggaacttt atcaacaaaa tctggaatgc
     2881 ttcacgtttc gttatcatga atatcgaagg aatgaccgta gaagagatcg atttatctgg
     2941 agaaaaatca gtggctgacc ggtggatcct tactcgtttg aatgaaacga tcgaacgagt
     3001 aactgagcta tttgatcgtt ttgaatttgg tgaagcaggt cgacaactgt ataactttat
     3061 ctgggatgat ttttgtgact ggtacatcga aatgagtaaa gaagtacttt atggagatga
     3121 tgctgtttca aaacaaacca cccgtagcat cttagtccat acacttgatc agatcctacg
     3181 tttattgcat ccaatcatgc cattcgttac agaagaaata tgggaacata ttcctcatca
     3241 gggaaattct ctagtagtgg cagaatatcc tgttgtacgt ccagagtttg atgatgaaac
     3301 agcttctaaa gggatggaag tattgaaaga attgattcga gccgttcgaa atattcgttc
     3361 agaagtgaat acaccattgt ctaaaccaat tacgttgcta attaaaacaa acgatgctaa
     3421 aatcgatcaa tttttagttg aaaatacaag ctatatcgaa cgcttctgta atcccgaaga
     3481 gttgacgata tcaagtgaga tcactgcgcc agatctagcg atgtcagctg ttctgacagg
     3541 tgcagaaatc ttcttgccgt tagcaggatt gatcaatatt gaagaagaaa tcaaacgatt
     3601 agaaaaagaa ctggaaaagt ggacaagcga agtaaaacgt gtccaaggaa aactttctaa
     3661 tgaacgtttt gtttctaacg cgccggaaga agtagtagag gcagagcgtg caaaagaaaa
     3721 agattattta gagaagcaaa cggctgtcaa agaacgaatc gaaagtttgc gtactattca
     3781 ataagaatag aaaaagagag tgtgaaatca gctagctatt actaaaagct agctgattga
     3841 acatcgttac aggaaagagt ttgagcctca ctcttagctt cgattcataa ggagatgtga
     3901 cataaatttt gtcgcatctc ttttttagtc tactcttatt atgtaggaga aggagggagg
     3961 tggatcatgt atcaagagtc aataaagtag ttgataaaat cgttcctctc tctgtttctt
     4021 ttctctttgt catactttta tttttcttat gtgttctatt tgttataata aaagagaaat
     4081 gggggaattg ttgatgacga ttgaagaagc aatagaatgg atccatagtc gattaccatt
     4141 tggttcacgt cctggccttg accgagtcga agctttatta gaagtggtag ggcatccaga
     4201 gagaaaagta aaaacgatcc atatcgctgg aacaaacgga aaaggttcta ctgtagctta
     4261 tttgagaagc ctattagaag aggctgggct gacagtaggt acatttactt caccttatat
     4321 cgaaacgttc aatgaacgga tcgcaatcaa tggcaaaagc attccagaca atgatttgat
     4381 ccagcttgta aaaaaatatc agccactgat caaacaactt gatcaatttg aagcagtagc
     4441 tggtattact gaattcgaga cattaacagc aatggcattt gattattttt tgatgaagaa
     4501 agtggacgta gcgattatcg aagttggctt aggcggctta ttggattcta ccaatgtagc
     4561 tgtaccaatg ctgacgggaa taacaacgat tggacttgat cataccgaaa tacttggaga
     4621 tacaattgaa gaaatcgctg cacaaaaagc tggaatcatc aaacaaggcg ttccagtagt
     4681 aacaggaaat attgccccag aagcttttac tgtcatccaa caaacagcta aagcaaaaaa
     4741 tgcaccgctt tatgtatacg gggaaaatta taaaataaac tatctgcatc ctgatgagat
     4801 gtggggagaa gtatttgaat tttttaatga aataggaaag atccctcaat taaccactcc
     4861 gcttttaggg caacatcaag ctgaaaatgc aggagtagcc atcgaattgt attttgttta
     4921 ctgtcaattg gaaaagctgc ctttccgaga aaaagatgtt ttgaagggat tgaagaaatc
     4981 tcgatggcca ggaagaatgg agcgtttgag taacgagcca ttagttgttt tagatggtgc
     5041 ccataatacg catgcaatga accggcttgt tgagaatttg aaaaaagaat tcaaaggata
     5101 tcaaatcaac attttgtttt ccgccttacg aactaaaaat gttagagaaa tgctagaacg
     5161 attgcagcaa gtaccaaatg tccatattta tttgacgacc tttgaacatc caaaagccat
     5221 cgaattaagt gaagtatcag atttagcaag tgagagagta tcaatcgttt cattgtggca
     5281 attcggatta gcagatatat tggaaaagat gacaaatgaa gacgtattag ttgtgaccgg
     5341 ttcactttat ttcatttcag aagttcgcca tttattaata caattaggag gagatcatga
     5401 agtataatgc agtgattttt gacatggatg gtttgctgtt cgacacagag ttagtgtatt
     5461 acgaagccac acaagtagta gcagacaaga tgggttttcc ttatgataaa gacctgtatt
     5521 taaaattctt aggtgtttca gatgaagaag tatgggcgaa ttatcatatg attttctcgg
     5581 aatttggcaa aacaagtgta caaagattca tagatgattc ataccaggaa acgcttgaac
     5641 gtttttcgca aggagcggta caaatgaagc ccggtgtgtt ggaactcctc tcttttttag
     5701 aagaacatca gattcccaaa gttgtcgctt ccagtaacca acgagcagtc attgaacttt
     5761 tattgaagaa gaacaatctg tttgaacgat ttgagacgat tgtttctgca gaaaatgttc
     5821 aacgagcaaa accagaccca gaaattttct tgttagctaa tcagaagcta ggtacagcga
     5881 agaaagaaac attgatttta gaagattcac aaaatggtat tttagcagct tctgcggctg
     5941 agatcccggt agtcatggta ccagatctgc ttccaccatc ccaagaattg atcaaaaaaa
     6001 cagctggggt tgtttcttct ttacatgaaa tccctgcatt gttaaaataa aaatccatct
     6061 cttttcgtat cttattttag ataagataga aaggagatgt ttttttggga aaacgattga
     6121 tcaaagaagt acctactagc tctttaccaa gggaacgtat ggaaatttat ggcgcggaag
     6181 ctttatcgga tcaggagctt ttggcaatct tactgcgtac cggtcaacac ccttatagtg
     6241 tgatgtcgat tgctggaaat ctgttaaaaa cgtttggagg actggcctct ttacgacagg
     6301 ctactttgca tgagttagaa gagattcgag ggataggacg cgtgaaagca atcgaaatca
     6361 aagccttgat cgaattaggt cgacgaattc agacggatca tgaaagagcg gctccaccgg
     6421 ttcgtaccag ctacgaattg gcccagcaat tgattctgga aatgaaagat cacaaacaag
     6481 aacatttggt ttgtatttat ttggacacga agaatcaagt gatcttaaaa aaaacagtgt
     6541 tcatcggttc gctgaatcag tcagtcgctc atcctagaga aattttccat tatgctgtac
     6601 gttattgtgc agcaaggatc gttttagcgc ataatcatcc ttctggtaat gttattccat
     6661 cgcagcagga tatgaatttt accaaaagga tacaaaagtg tggagaaatg atggggatca
     6721 ctgtactgga ccacttgatc atcggacgca aacgatattt tagtttgaga gaagaaggaa
     6781 tgatggaaga gaagtaagtt gctttcttgc aaaaaaaatg aagcaagtgt acaattatat
     6841 tgtaattttg tttgggaata gaagttgaaa catctgttgc acctctatcg tacacgagca
     6901 atgttacaat ttaaattagt gcttttggca cgaggaggat attattatgg aaaacggaac
     6961 agtaaaatgg ttcaacgctg aaaaaggatt tggatttatc tcacgtgaag atggaagcga
     7021 cgtattcgtt cacttctcag ctatccaagg tgacggattc aaaacattag aagaaggtca
     7081 agcagtgact ttcgacgttg aagaatcaga ccgcggccca caagctgcaa acgttgtaaa
     7141 agcttaattt tatctgtaaa tcaaattgat ggtagacatc aatttttacg agagaacaaa
     7201 gcgagtaaca aaaatacctg ccacaagaga caatttctct tgtggcaggt atttttttgt
     7261 atgaaaaagt aaataaattt aagaggctat gaaagagcca ccttgtatca aggaataaga
     7321 acaaacaaaa atggcttctc atgtttttca tttgttttct cttatattca ggacaaggtg
     7381 ctgatttcat aacctcttat ttattcttca tctggtgtca ttaccattgg caaaatcatt
     7441 ggatgtcttt ctgtacgttc gaataagaaa ggctgaagcg cgccagtcat cgcttctttc
     7501 aatttatatt ctgaacagtc aggtccattc aaacattctc ttaaagcgtg gaataagatt
     7561 cgctgagctt cattgatcat ttctcctgat tctcgcatgt agacaaatcc acgagagaga
     7621 atatctggac cagccaagat ttcttttttc ttgatatcca ctgtcgcgac agctaataca
     7681 agaccttctt ctgaaagcag gtgacggtca cgtaaaacga cattaccaat atcaccgatc
     7741 ccgctaccat cgatatacac atctccagcc acaaaatgcc cagcaggacg cgcagaatcg
     7801 ctagttaacg ctaaaacatc gccattttcc atgatgaagc agttttctgc aggaacacct
     7861 acatcttgtg ctagagaagc atgtactttc aacatgcgga attctccgtg gacaggaata
     7921 aaatattttg gcttcatcaa acgaagcatt aatttttgtt cttcttgtcc accgtgaccg
     7981 gaagtatgga tgttattgat ttttccgtga atcacttctg caccagcttc agacagcaaa
     8041 ttgatcaaat gattgacact tgttgtatta ccaggaatag gtgaacttga aaagatcact
     8101 gtatcgtctg gctggatttg gatttgacgg tgagtaccat tcgcgatgcg gctcaacgcg
     8161 gccatcgctt ctccttgaga acctgtacat aggatcatcg tttcattggc aggcaagcga
     8221 ttgatttcgt gtgcatctac aaatgtgccg tctggaactt tgatatatcc taaacgttga
     8281 ccgttgacga tggcattttc catgcttcgt ccgaaaacag cgattttacg accagttgcc
     8341 acagcggcat ctgctgcttg ctgcaaacgg aagatgttag aagcaaagct ggcaaaaatg
     8401 atacgtcctt cgatttttga aaagatcttc aaaatagaat gcccaatcgt tttttctgat
     8461 ttagtaaatg ttggaatctc agcatttgta ctatcagata aaaggcacaa gactccttct
     8521 tccccgatac gagccatttt atgcaagttt gctggttcgc caacaggagt gaaatcgaat
     8581 ttgaagtctc cagtcgctac gatatttcca gaaggtgttt tcaccacgat ccctaatgca
     8641 tctgggatac tatgggtcgt tctgaaaaag ctgacagaag tctttctaaa acggatgatc
     8701 gtatcttcat tgatctcatg gagctctgca tctcgaagca agccatgctc atctaatttg
     8761 tttgtgatca acgctaatgc gagaggacca gcatagatag gaatatttgc ttgtttcagc
     8821 aagtagggta ttccgccgat gtggtcttcg tgcccgtgag taatcaccaa ggcttttact
     8881 ttgtgtaagt tttgtatgat gtagctgtag tcgggaatga catagtcaat tccaagtaaa
     8941 tcgtcttccg ggaatttgat cccggcatca atcaaaatga tttcatcttg gaattgtacc
     9001 ccatacgtat ttttcccgat ttcacctaat ccaccaatag caaagacgcc tgtctcgtta
     9061 tttttgatgg aaagtttcat attaaaactc cactaatgag aaatcagcat tttctttttc
     9121 gtactctaga tgacttcctt ctagaagttg aacgaattca atattgtatg gggtattttc
     9181 ttccacacgt tggcgagcgt ctacatcgct ttttgcctca atgtaaagag attttgtttc
     9241 ttcccgttta gggttgcgta cttttgtttc ttgataataa actttataga tcattgtttt
     9301 gtctccttta tctgcgtaaa gcagtgattt agctagttga tttttttaga caacacaaaa
     9361 cgaggggaca agccacctgg tttttcatat gctttgacta gaatactgga ttcgagtcaa
     9421 agagacaagc ctcgtttttg cttatctgtt cggatatttt ttcaaccgta ccttctgtat
     9481 aaaaaatata caacaattaa ttgttattct agcataaaac agcaaataag tatagaaatc
     9541 aactagattg aaagaaaaaa tcaatgttta tcatcccgct ataatcataa tgactttttt
     9601 atgagagaag tgttctatta ataggctcgt tgtgctatca tttttagtaa tgaaaatgta
     9661 acaaaagatt aaaaggagat gagaaagtga aactaatgtg gcattatacc atgcgttata
     9721 agaaattctt gtttttcaat ttcatatgcg tatttggttt tattttgatt gaattaggac
     9781 ttcctacgat tttagcacgt atgatcgatg taggaatccg caatgatgat tttgattatg
     9841 tgaagcaaca agggatattt atgatcgtta ttactgtaat cggtattatt ttgaatatct
     9901 tgttaggtta ttttggttcg aggattacga ctaatatcgt agcagatatt cgagatgatt
     9961 tgttcgaaaa gatccaaagt tattcgcatc aggaatacga aaatctaggc gtatcttcat
    10021 tgatcactcg tacaacaaac gatgcttatc agatcatgtt gttcctgcaa aatattttac
    10081 gtatcggttt tatggcacca atgatgttca ttgtcagttt gtacatggtc atgcgtacaa
    10141 gtgtgacact cagtttgtat gtagtaggtg cattaccttt actattattg gcagtcgtag
    10201 cgattgctaa ggtgtctgaa ccgttatcta aaaagcaaca aaaaaactta gataaaatca
    10261 acagtatctt gcgggaaaat ctttcaggat tgcgtgtgat tcgtgcattc gtcaatgaaa
    10321 agtttgaaga aaaacgtttt gctgtagtca atgagaatta tgcttctagt tcaaaaagct
    10381 tattccgttt gatggctgtt gcacaaccgg gtttttattt cttatttaat atcgtaatgg
    10441 tattgatcat ctggagcggg gcagtgcaaa tcgatgcagg cgagcttcgt gtaggagatt
    10501 tgattgcgtt tatcgagtat atattccatg ccttgttctc attcatgtta tttgctagtg
    10561 tgttcatgat gtatccaaga gcagctgttt cagctggacg tatccaagaa gccctagatg
    10621 ccaaaccttc gattgtagaa gatccaaatg gtatatctga tacaaaaact aaagggtata
    10681 tcgaatttca aaatgtaaca tttgcttatc caggccattc gcaagagcca gtgatacgaa
    10741 atgtcagttt tacagcctct ccaggagaga ccgttgcttt tattggaagt accggtagcg
    10801 gaaaatctac gttgatccaa ttgatccctc gcttttatga tgtgagtgaa ggaaagatct
    10861 tgatcgatgg agtagacgtg agagattatc ggctaagcaa gttgcgagat aagattgggt
    10921 ttattccgca aaaagcgctg ctatttactg gaacgattgc agataatttg cgatacggga
    10981 aagaagatgc tacgcaagaa gaaatggaac gtgcagctga gattgctcaa gcttcagaat
    11041 tcatttctcg aaaaccagat ggatttaatg aacatttatc agaaggtggt tccaattttt
    11101 caggtggaca aaaacaacga ttggcaatag ccagagccat catacgccgt ccggaaatct
    11161 atatttttga tgacagcttt tctgcattag attatcaaac ggatgcgaag ttacgtgctc
    11221 gtctgaaaaa agaaacgaca gaatctactg tattgatcgt agcacaacgt gtgggaacga
    11281 tcatgcatgc agataagatc atcgtattaa atgaaggaga agtcgtcggt atggggacgc
    11341 atcgggagtt gttggaaaaa tgcccgattt attatgatat tgccgcttct caattatcaa
    11401 aggaggaatt agcatgaaaa aaaccttttc ttccttaaaa cgtttagctc gatatatcag
    11461 accgtatcgt gagacttttc ttttagtgat cctatttaca gttctgacag tggctttcaa
    11521 cgtggctttg ccatatgtta caggacttcc tactacagaa atcagccgta atattgccaa
    11581 tggcgaatca atcaattttt cttatatatt caaatgtctc atttggatca cagttgttgg
    11641 aatagggtat tgtatttcgc aattactttc tggtgttttg atgacaaatg tcgttcaaag
    11701 tgccatgcat gatttgagaa gagacataga agaaaaaatc aatcgtcttc cggtttcata
    11761 tttcgataaa aaccagcaag gaaatatttt gtctcgtgtg acgaatgatg tagatgcagt
    11821 cagcggtgct ttacaacaag cttttattgg tatcgtaaat gcgatattgg gaattacgtt
    11881 ggctgcagca atgatgtttt atatccagcc gatgatggcg ctgatctcta tgatcatgat
    11941 tccaacatcg atctggatct caaaacgagt gatcaatgct tcgcagaaat attttcaaag
    12001 catgcagaat tctcttggtg agctaaacgg ctacgtccaa gaaaatatga caggttttag
    12061 tgtattgaaa gtatatggac gcgaaaaaga aacattggaa ggattcaaaa aagttaatca
    12121 cagcttgaaa tactttgggt ttcgtgcagc attcatttct ggcttgatga tgcctctagt
    12181 tcaattaact gcctatgcta cttatattgg tatggctgtt ctaggaagct tttatgttat
    12241 tactggggcg atcgttgtcg gtcaactaca agcattcatc caatatattt ggcaaatcag
    12301 tcagccaatg gggaacgtga cacaattgtc ttcagttttg caaagtgcat cagcggcaac
    12361 gaaacgtgta ttcgagattt tagatgagcc agaagaaaaa gaaaacaaag tagatgcttc
    12421 actgccagaa acgattttag gagatgtgac attcgatcat gtcgattttg catatgatcc
    12481 gaagaaacca ttaatccaag atttgaattt tgaagtgaaa gctggtcaaa ccgtagctgt
    12541 ggtcggtccg accggtgccg gcaagacgac attgatcaat ctattgatgc gtttttatga
    12601 cgtagacaaa ggagcaataa ggattgatgg aatcgacacc aaatcaatga gtcgcagtga
    12661 tgtgcgttcg ctatttggta tggtcttgca agatgcatgg ctttatcaag gaacgattgc
    12721 agataatatc cgcttcggaa agcttgatgc gacagattat gaagtagttg atgctgcgaa
    12781 aacagcaaac gtagatcatt ttatccgaac gatgccagat ggatatgata tggccatcaa
    12841 ttctgaggga gacaatgtgt ctttaggaca aaaacagttg ctgacgattg cccgagcagt
    12901 ggtctccgat cctaaaatct tgattttaga tgaagcaaca agttcagtag acacccgttt
    12961 agaagcgttg attcaaaaag caatggatcg cgtgatggag ggacggacaa gtttcgtcat
    13021 cgctcaccgt ttatcgacaa tccgtgatgc agatctgatt ctagtgatgg atcaaggtca
    13081 gatcattgaa aaaggaacgc atgagagttt attggcacaa ggtggatttt atgaaaaact
    13141 gtataacagc caatttgctg aggaagcaga ataagtcata taagaataaa acagtttaaa
    13201 acttattttt tgttctctat tcttgataat ggtaaagtaa agttatcaag aaaagtgagg
    13261 acacggagat ggaacagttt ttaaatgaaa aaattactga agccaaaaga gaagttgatc
    13321 gtttaacgca cgtctgtcag acgaagcctt ttgattcagc tgattttttt gaaaatgagt
    13381 ttcaaatcga acgcttggca gcacaaatag aagtgtacga attaatttta aaaaaagtaa
    13441 tagaagaaaa tatagatgta caataaaaac aggtaaaacg tcagttacca gatactgtaa
    13501 atagacatct ggcctgagca ggttttacct gttttttttc ttatgaaata aatatatgct
    13561 atgatacctt tattcaatag gattagtttc tacaaaaaat gaaaggagaa aaataaatat
    13621 ggaacggttt atagcatcaa atgccacagt gattggtgat gtgacattgt cagaagatgt
    13681 gacgatctgg tatcaagctg ttttacgcgg ggacagtaat tggataaaaa taggacaaag
    13741 aacgaatatc caagatggta caatcatcca tgtcgatcat gatgcacctg tagatattgc
    13801 ggagaatgtg acggtaggac atcagtgcat gctacatggc tgtacaatcg aaaaaggggc
    13861 gctgatcggg atggggacca cgatattgaa tcatgcggtt attggtgaga atagtttgat
    13921 tggtgctgga tcattagtaa cagaaggaaa agttattcct cctaatgtct tggcttttgg
    13981 tcgcccagct aaagtgatcc gtcctttgac aaaagaagaa atacaaaaaa acaaagaaaa
    14041 catccagcat tatgtcgaga taggtcggat gcatgcgcaa ggaaaattca aggagcaaag
    14101 ataggcagta gcatccataa aataaaaaag gatggtcagt ttgagttgac catccttttt
    14161 tatttggttt agataagaga gcttaaaaaa gcttcctttg aaacagatta atttaatgaa
    14221 gaactgtttt ccatgacttc atcgatcaat ccatatgctt ttgcttgttc agctgtcata
    14281 tagttgtcac gatctgtatc tttttcaatc acttcaagcg gttgtccagt gcgttcagct
    14341 aaaattttgt ttaagcgttc gcgtgtttgc aaaatatggc gtgccgcaat ttcgatttca
    14401 gttgcttgcc cttgagcgcc gccaagaggt tgatggatca tgatctcagc atttggtaaa
    14461 gcaaatcgtt taccttttgt accagctgtc agcaagaagc ttcccattga agcagccata
    14521 cccataacaa ttgtttggac atctgctttg acaaagttca ttgtgtcgta aatagccata
    14581 cctgctgtaa ctgaaccacc aggagaattg atataaagat agatatcttt ttcagaatct
    14641 tgagcgtcta agaaaagcaa ttgggcgatg atcgaattag caagatcatc tgttacttgg
    14701 ccgcttaaca tgatgatacg gtctttcaat aaacgtgagt agatatcgta agctctttca
    14761 cctcgtgaag attgttcaat gactgtagga attaaattca taatagagtt cctccttgat
    14821 ttcgtttaga aatagtgtac cataatttag tttctaatac ctaaaatgta gtatacattt
    14881 ttggtcaaaa aaggtcaaat aaaaaactta ggcaaattag tcgcataaac ccgctttatg
    14941 gtatgataag cagagaaaca aaacaaggag gaacaacaga ttgatagttg gtattactgg
    15001 ccttatcgga gtgctgacag gtgctgtagt tgtctatatc ggcatgatac tgcaaatgcg
    15061 tcacttggaa aataaagaac agcgtagacg tgaattggaa ttgaaagtca aagaaatcga
    15121 gacgctgaat caattaaata aaaagatcaa cgagatcttg caaaaacgga caacgctgat
    15181 ggaagaatat gtcagctttg atgcatttga tgattgttat atcacgattg acgattttgc
    15241 gtatctccaa tcattttcag cgcaaaatag tttttatctg ccaaattata ttttagacga
    15301 gctatttaag aatatctccc atcgaaaagt gattttatct ccagatgaaa caatgaagat
    15361 tggtggatat gcttataaag gcggacgcgt gattttagag aattttacgg atagtctgac
    15421 tgaaatgatc aatgaaaaaa aagctcagtt gaagactatg acgcgccagc cgattggttt
    15481 cttctcgaaa gatgatgttt ggagctgata ttttgaagca ttgccgttgc acatgagagc
    15541 gtggtaatgc tttctttttt tcttaatgat acaatagaac tgaacggagt gaagaaagat
    15601 gttacaaatc tatgcccatc gcggaagcag cggcacccac ccagaaaata cgcttcctgc
    15661 atttgcagaa gctgtacgag taggtgcaga tggtatcgaa ctagatgtcc atctaagcaa
    15721 agatggttat ttgatcgtta tgcacgacga agaagtggac cggacgacta acggtaaagg
    15781 gctgattcga gaaaaaacat tggaagaact caaaaaattg aatgcagggg gcaaattcag
    15841 caaagaattt ccagcagcta aagttcctga attgagagaa gtgttaggac tgctcctcca
    15901 aaaaaattac cgagggatgc taatgattga aattaaaact gatcagtatg aatatcccgg
    15961 tatcgaagaa aaattagccg aaacattaaa aagtagagat tggccttttc aacatgcata
    16021 ttgcagcttt catttggatt ctttggaaaa aatcgcatta ctggaaccgg agatacagct
    16081 ggacttattg atgagtactt ctgataaaaa gatccaacta gcagcagaaa ccccttatat
    16141 agaaggagta catccaaaaa atacttggtt gttcgaacat ccagtccagg cagctgattt
    16201 tccaaaagca attcgtgcat ggacgattaa cgatgaagaa gaaatggcca aatgtcaaga
    16261 actcaaaata gatggaataa taactgattt tccggagaaa gctcttcggt ggaaacaatc
    16321 aacgaaaagt aggtaaaata tggaaaaagt attagtgatc gtcggtccga cagcagtcgg
    16381 taaaacagcg ctaagtgtgg aactcgcaca actatttgga ggagagatca tcagtggtga
    16441 ttcattgcaa atctataaaa atctggatat cggtacagca aaaatcaaag aagaagagat
    16501 gaataatgtt ccgcatcatt tgattgatgt gatcgaacct actcaacgtt actcagccgc
    16561 tgattttcag cattcaggtc gacaattgat taccgagatt gcgaaccgag ggcacctacc
    16621 tatcatagct ggtggtacgg gtctctatat ccaatccctt ctatatgatt atcagttagg
    16681 agcgacagaa gaagcgaatc ctgagattag aaaaaagtat gaaacgttag ctgaaacaat
    16741 tggttcccaa gcattatgga atcagttgaa agaaaaagac ccggcagctg ctgagaaaat
    16801 ccactggaac aatcaacgca aagtgataag agctctggaa gttttagaga cgacaggaca
    16861 tagtatcacg gcacctaaag aagagccaaa gcaattgtat gattacctca tgattggatt
    16921 agatacgaag cgtagtattc tttatgaacg aatcaatcaa agagtcgatt tgatgctagc
    16981 agaaggttta gtagcagaag cgcgtaaggt gtatgagctt ggagaagtcc aggccagtca
    17041 aggtattgga tataaagaat ttttccctta ttttgaaggg aaagaaacat tggaagaagc
    17101 aacagaacaa gtcaaactac attcgagaag atacgcgaaa cgtcagttga cgtggtttcg
    17161 taaccgtttg gatgcacagt ggtttgatct tataagtgag ccaaatcaaa aaagtcagat
    17221 tgagcaaaca atcaaaaaat ggctggaggc ggaataaaat ggaagaaaaa gtgatcatcg
    17281 taggggtaga aaccgaagca aaccagcgtt acttttcaga gtcaatggaa gagctagttc
    17341 agctgacgaa taccgcatca ggagaagtcg tattcacaat tacacaaaag agaccacaag
    17401 tggatcggca aacgattatc ggtaaaggga aattacaaga attagttcaa caagcggatg
    17461 cgcatgaagc ggatttgatc atctttaatc atgagctaac tccgagacag agccaactga
    17521 ttaccgatgc tgttggtctt ccggtaattg atcgcgtgca gcttatctta gatatttttg
    17581 cgatgcgtgc tcgttcgaaa gaagggaagc tgcaggttga acttgctcag ttagaatacc
    17641 tgctgcctcg tttagtaggg caagggaaaa cattatctcg tcttggcggt gggatcggaa
    17701 caagagggcc aggtgaaaca aagttagaaa cagaccgccg acatatacgg aataaaattt
    17761 ttgctgttaa gaaagaattg aaagaagtag aagctcatcg agagcgcaat cgccaaaaaa
    17821 gaaaaaatag cgagattttt cagattggac ttattggcta cacgaatgcc gggaagtcaa
    17881 ctatcttgaa tctattgaca caagcggata cttattcgaa agatcaattg tttgcaacgt
    17941 tagatccatt gactaagaga tggcgttttg ctgaaggatt tgagattact gtaacggata
    18001 ccgtcgggtt catccaagac ctgcctacgc aactgatcga tgctttccat tctacattag
    18061 aagaaagtca aaatatggat cttttgctac atgtagtcga tgctagttct ccagatcgta
    18121 ttttacagga gcagactgtc ttaaaattga tggatgaact gaatatgaaa gaaatgccga
    18181 tactgactgt ttacaataag gcagaccaga tcgacccagc gatgttcacg cctacgctat
    18241 tcccaaatgt attgatttct actcagacga aagaaggtaa gatggcgttg atcgaagcaa
    18301 tcaaacgtca gctgatggaa ctaatgaccc cttatacact ttctgtgcca agcaacgaag
    18361 gacagaaatt aagcgagttg agaagacaaa caatggtttt ggacgaagcg tacatggaag
    18421 aaacaaacga atatgaagtt aaagggtttg caaaaaccaa ttcaaaatgg ttaagaaaaa
    18481 accaataaaa ttttattttt ttaa
//
LOCUS       DAFLWQ010000055        18437 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.056, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000055 DAFLWQ010000000
VERSION     DAFLWQ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18437
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.056"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(32..943)
                     /locus_tag="L1V16_001898"
     CDS             complement(32..943)
                     /locus_tag="L1V16_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBN1276238.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(1320..1958)
                     /locus_tag="L1V16_001899"
     CDS             complement(1320..1958)
                     /locus_tag="L1V16_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1276239.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDFVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFNQETKHLTGREKRLIKRNALSFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKEQVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(1962..2732)
                     /locus_tag="L1V16_001900"
     CDS             complement(1962..2732)
                     /locus_tag="L1V16_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBN1276240.1"
                     /translation="MIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQE
                     ISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSTYWERNILSGEIYPPLK
                     IKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFS
                     FFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIER
                     EPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            complement(3150..3566)
                     /locus_tag="L1V16_001901"
     CDS             complement(3150..3566)
                     /locus_tag="L1V16_001901"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276241.1"
                     /translation="MMTREKEAYERFILLFVERFNQAFHTDYATNIFEDFENSYSYSV
                     ISSTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNGFSLHQVLWCLLGKKKI
                     IITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGI"
     gene            complement(3617..3998)
                     /locus_tag="L1V16_001902"
                     /pseudo
     CDS             complement(3617..3998)
                     /locus_tag="L1V16_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339091.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4124..4789
                     /locus_tag="L1V16_001903"
     CDS             4124..4789
                     /locus_tag="L1V16_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1276242.1"
                     /translation="MNIGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHQTLGLPIDFPSIESATESIEPTLPDEPLVIKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETVDRFNPFLKPQIGYTTLPVGYVENSIEHWVCNDIFVHGTW
                     LSFHAGEVEKGKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILIQDYDDALKRSPQEP
                     DRH"
     gene            complement(5186..7219)
                     /gene="brxL"
                     /locus_tag="L1V16_001904"
     CDS             complement(5186..7219)
                     /gene="brxL"
                     /locus_tag="L1V16_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease Lon-related BREX system protein BrxL"
                     /protein_id="HBN1276243.1"
                     /translation="MEQQEILKLSEFFPGKIVRKDLTKKIKEGANVPVYVLEYLLGMY
                     ASSLDETLVEKGVENVKNILARNYVRPDEAEKVKAKIRELGGYTVIDKVTVHLNEKKD
                     CYEAEFSNLGLKNVQISEEYPKKFDRLLGGGIWCIVSMEYWYDENDRWNSPFIAKKVD
                     PIQMPGLDIEAYKMARKEFTTNEWIDLLLRSIGMEPTQFNKRVKWLHLARLIPLIENN
                     FNLCELGPRGTGKSHVYKEISPNSILVSGGQTTVANLFYNMASRTMGLVGMWDCVAFD
                     EVAGIKFKDNDGVQIMKDYMASGSFARGKEEKNASASMAFVGNINQSVDVILKTSNLF
                     EPFPEVMGTDSAFLDRMHCYLPGWEIPKYRPDFFTNDYGFITDYFSEVMRELRKVSFG
                     DSFDKYFKLGSQLNQRDTIAVRRIVSGMMKLLYPDGRFEKSDVEEILRFALEMRRRVK
                     EQLKKIGGMEFYDVNFSYIDLEEEREEYVSVPEQGGGTLIPEGLGKPGHLYTVSYGKT
                     GQLGTYKLETQMTSGNGKFERTGINSDAGAREAMDSAYRYLRANYGSVSQSISLTTKD
                     FVVHVQDMNGIGMTKTLSLSTIIALCSVSLNKPVLPSLVILGDITIGGSMIKVDNLAN
                     CLQVAKDAGAKKVLVPMISAADIGTVPPELMGTFNLIFYQTPEDAVFKALGVE"
     gene            complement(7337..9859)
                     /gene="pglZ"
                     /locus_tag="L1V16_001905"
     CDS             complement(7337..9859)
                     /gene="pglZ"
                     /locus_tag="L1V16_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system phosphatase PglZ type A"
                     /protein_id="HBN1276244.1"
                     /translation="MTDINTQQIEEKLNQRFPNYGCRKIIFWFDSNQDFLEEIDSLVI
                     QNAKIYRLEKDAQFKTKRLLEYEDPETNYLIYAPFPRWDDKDEDNHLLSVLNYSEEFS
                     ADRLAIIMNELAIPLRFHQTVKQYRNFFNAKDRMRSFGEFSTHMTINKSETIELMIMA
                     VLLKSKSIRLNDLLRVVLKSFTESRENPLRELDKYQLTAKFWEFIQMKFGFTDSQPTL
                     EKLTMCLYLNYFYYQIDQEMPKKFKGFEILHLKANIITFMDQFMNDTRYMESFEQLSK
                     KVYQAIDGDGLLDSIEIDDLIEADVFSEIHAKILMFYAERLKASDTTTKIAGQTIFDS
                     LKQREKMHFASDYIYEYQLLKHAYYLVDKNRLCLPMNMDNLLTQYEKEMYWVDTHYRK
                     FIWNSDHIEEKQKYGQLYRLVEANYSKFLDQSGQIWNQTFEFKNRPSIRKFYNQAVMK
                     RSVKTVVIISDAFRYELGMNLERKLVREKKYSTNMASFLSVLPSVTEFGKAALLPNNQ
                     LTYNEGTEVLIDGKKTNGLSNRNAILQQRDANAVALNYDDVVKMNKAEVREVFNGKSV
                     IYIYHDQVDRTGDHSNENRVFEACDLAISEISRLINRLHNDGSIYRFIVTADHGFIYK
                     RSHVEEVDKIENPSRNEKDRVERRFILSEEEYEIIGTKNYSLGDSLGNDDTRNICVPI
                     TSSIFKKAGGGQSYVHGGSSIQEMLVPVLEITVAKGSNAKEPVAIELMTSNRRITGLS
                     TTLEFYQKNAISDVYDPASFWLYFEDEYGERISNEEIYVADSKTEDANQRFTKFVFEF
                     VNRRYTVEDTYYLVIKNQKNDLTERIKFIIDNPFAESFDFDI"
     gene            complement(9975..13607)
                     /gene="pglX"
                     /locus_tag="L1V16_001906"
     CDS             complement(9975..13607)
                     /gene="pglX"
                     /locus_tag="L1V16_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system adenine-specific
                     DNA-methyltransferase PglX"
                     /protein_id="HBN1276245.1"
                     /translation="MDKKAIKNFAVNARRKLIDEVMTKAKRLGIDESKIEDVKKIDSN
                     LQEIEKSGIRIQGKEIAQRNKLIAELKQRASVTSYSEAFQELIEEVAYTWFNRLIAIR
                     FMEVNDYLPDTYRVLSSEISGKIEPDIITDIYDADIFEELSSNEQQQVRTWKTDNSAE
                     AMDKLYQLIFIKICNQLNDYLPELFEEVEDYTELLFTASYIKKDGVIADLLSIPEDDF
                     YVQAGGQVEIIGWLYQYYNSEPHNQVVNIYKGIVKKQDIPAATQLFTTDWVVRYMVDN
                     SLGKYWLDHYPNSELRNKLKYLIPDKYAFEQATSVSNLKPEELKIIDNAMGSGHILVY
                     AFDVLMEIYLTLGYSERDAARAIVEYNLYGLEIDKRAYQLSYFAIMMKGRQYDRLFLK
                     KSLSPNLREFIDSPKVTDEYQERISELNNDKYSERWNEYKELIFDQFENGKELGSIIK
                     LVDKNNQAITKEYLGKVREYISKFNEFTNMDILYGMKEIQEKYLHILDVAEMLVDKYV
                     AVVTNPPYLNKMDKKLKKYVNDNYSDVKKDLFSVFIKLNSQMLIDNGYASFMTPFVWM
                     FISSYEKLRSFLINERNISSLIQMEYSAFEEATVPICTFTIKNSNEQDGSYIKLSDFK
                     GGMEVQKIKTLEAIHQHGECDYFYSTNQDNFKKIPGMPIAYWASDNVITDFAQGKLTN
                     DVADAKQGLATGNNNKFLRYWFEVEFNKIKFDAKTLEDAKKSRKKWFPTTKGGRFRKW
                     YGNNEYVVNWENDGDEIKNYVNENGKLKSRPQNLNYYFKKGITWSTLSSGQVSFRLQN
                     QAIFETKGSVLFSKDITDFEEIFGYVNSKLVNHFLTFISPTLDYHEGPMGKLPFLKVT
                     SERKLKKIREKVDENIDIARKDYNALETSYEFRRNILLSYMFKKDLSEAFNCLSRQLV
                     NQFNTLKSNEEELNDIFINHYSLEKELTKEVQDEYISARLPDKAREIKDFISYSIGCI
                     FGRYSLDEDGLIFAGGEWDPSRYQKFKPDTDNVLLITDDEYFKDSQIDIVNRFIDFVE
                     ITFGKETLEENLQFIADTLGGKGTSREIIRRYFVQDFYKDHLKTYSNRPIYWQLDSGK
                     QNGFKALMYLHRYTPDQLGKVRTEYLHELQKAYDNRIELRQQQISTSDNPKERNAMTK
                     EIVKIQKQLKEVREYDEKLGHLALKRIELDLDDGVIVNYDKLQRDPKTGEKFQIFAKG
                     VKEPKK"
     gene            complement(13671..17342)
                     /gene="brxC"
                     /locus_tag="L1V16_001907"
     CDS             complement(13671..17342)
                     /gene="brxC"
                     /locus_tag="L1V16_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX system P-loop protein BrxC"
                     /protein_id="HBN1276246.1"
                     /translation="MLIKDIFAKPIDRNIQGVIKVGQAKDENVQQELEEYVVTKELQK
                     HFKTIFDAYQRSINTPTDKMGVWIQGFFGSGKSHFLKIISYLLANREINDKKAIDYFK
                     EDGKIKDPLTLATMERCSQINTDVILFNIDSKSDAGGKKDKNGIVNVFLKVFNEMQGL
                     STIPHLADFERRLIKEEKFDAFKAAFEEINGAKWQEERHEFDWIQDDIKEAALKIDFM
                     SEAAIDNFLEKASGNYLISIDDFANLVKSYLDSKEADHHIAFLVDEVGQYIGGNRELT
                     LQLQTVVEDLGRICEGKAWVLVTSQEAIDHVTNFDNNSDNDFSKIKDRFATTVSLSSA
                     NADEVIKERILKKKEFANDSLALQFETVQTELKNKLLFVDSPELKLFQDAENYAEVYP
                     FIPYQFNLLGQILTEIRNHSYQGSNLSSGERSLLAMFKEAAERNKENDTTSLVSLDQF
                     YYSLERWIDTAISRVITQATNNSHIQRPTDIDNFNVNVLRILFMIKYVDQAIKPNVEN
                     ITSLMIRNINEDRLETKKRVEEALDLLIKENFVRKNLDSYIFQTDEEQEITREIKNQN
                     ITDSDLIVELSKRIFDGVLDRNSFAYEKLGMSGGNKFKNRYTFTYAQVLDQRPYKQAG
                     NAEMTVNFISPYSDLAGQEAELALKSSRNLLFVELPSDKEFKDDIAMYARMNLYLTTT
                     YSSVVKNFDAIRSEKSGELQELSASINDQLNELLKSAKFFYNGAEIQLTGSDFKAKFQ
                     SALQKMAEEVYHKLNQIDAPKEKEDILYLVKESKNEIIEDPSNEQAVQEIFNFINDQK
                     RNHLTITMKTIRDRFETKQPYGFTELDVEWCIAKLFMSGKIDLLYNNVQISRMDDPNS
                     IVMIIQKRRESEKIKIEPSAVISPKAKKLVDEIGRELFQSRNIVDENNNEHTMENFKK
                     YLKGQLDNLRSYFDLQNTYTYPSAYEYEQIKKYLEVIVQTSDVEDFFYTIKKYRDELF
                     DWAETYDKIKNFHKQNSTQKKIWENAQDKIRLIEKSRRQTSSQEIDQLIHEMKTILKK
                     ADPYSDMMKLNELIQEFIEQYNQLLELESQEILNKLTEEKQATFKLLEGKDFKDQFVP
                     IVDQEFQELKAKIEQANTIDDLVFLSLNVAEQYLIFNQRFDNEENRRRQEEQARKQIE
                     AANLIRETEKDEIDSAAKAEEIAIVKPTIQQKTVPMRTLNVHVKTIKSAADIDELTAE
                     INQKLKEQLQENTEITIQF"
     gene            complement(17367..17942)
                     /locus_tag="L1V16_001908"
     CDS             complement(17367..17942)
                     /locus_tag="L1V16_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1788 domain-containing protein"
                     /protein_id="HBN1276247.1"
                     /translation="MSLSIQEHLEKLNEVIQKEDFLLNRGLGNEVGYYIFDYDPKDEL
                     IVRDYINDISGTSVGDNYEVKVYNLYVIMLEYLEKRGFTEKAIKMEERRGLQKLVESI
                     GRLLKMDLPEEENVFFEYVDAHTPEKSVVFLTGIGELYPLIRAHSILNKMHQVFDRVP
                     VVMMYPGEYDELSLTILNTNKDDNYYRAFRI"
     gene            complement(17942..>18437)
                     /locus_tag="L1V16_001909"
     CDS             complement(17942..>18437)
                     /locus_tag="L1V16_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1819 family protein"
                     /protein_id="HBN1276248.1"
                     /translation="KEKNEHENIFFAVSSNRQKEIYQNVKRRVSQLDEAGLQLFNQLN
                     IDNQKLVNLISILMIDDLFNEFMTEVYAENLRKGNLQLTPVDYRSFFTEKRRSSEDIS
                     KWKDYTIKRLIAAYQTNLIETGLVRGEKEYGRMTPILLDKRLIQWLVDKNRKDIVLAL
                     GGIL"
BASE COUNT         5673 a         3528 c         2589 g         6647 t
ORIGIN      
        1 ttaaatagtt catatttttt atttataccg cttatttact acttgctgta ctagaatctg
       61 aagtgaatgt actcaaaaca ttttcaaagt ctttgtcttt gatttttaca ttagcgtctt
      121 tcaatacttc gccaattact ttattctgga aggtactgtc acttaatttt gtgtctgttg
      181 caatttcttt caattctttt ttgtatttat ccatgtcgtt gcctttgttt tggtttttca
      241 ccattttaac cacataatat tccgtagtat aagttgaagc attggtagaa gtgatcacat
      301 cagaaacttg accatctttc aacttaaagg ctgcttcttt gacttctgcc ggaaccgttg
      361 tagtagtgga atcaaatttc acttttccgc catcttcttt tgtcgtagta tcagttgact
      421 tgtctttggc taatttagag aaatcgtctc ccttatcagc agctttcttc acatcttttg
      481 catcatcttc acttgctact tggataattt gagcttccac ttctggatgg aaagattccc
      541 aagccgtttt taaatcttca tcggtcaatt tgatatgttt ctttagacct tcttgaaagg
      601 ctagactttg tttgatactg tctttgaatg tttgttctgt gtaacctgca gatttcaatt
      661 gtgaatcaaa tgaatcaccc aattgtttct ttgtttgatc atattgggaa tcgatttctt
      721 tggttgatac gtcatctcca tatttatctt caaatacttg ataaacgatc aactgttgca
      781 cagcggaatc tgctccttgc atttttttca agctatccat tacttcttgt tcgctgattg
      841 taccgccttt ataactaacg gctgtttttt caccggcatt cgtacagcct gacaataagc
      901 cagtgcctag tacgatggca agtgctaaaa atcttttttt catttatcaa ttctcctact
      961 tttcgttttt tgcgaattgc taaaaacaaa ggtgttcaag atgaaaatca tcaagaacac
     1021 ctttactaat ctgctcgata cgtcctgaat agatataagg ctacacaatc cagaaagttc
     1081 gctcagcaga ataaatgtca agtagcacat cacaccttaa tatactactt cttttgttac
     1141 cgtttttcaa gtctatcttg cgttccgtat ttaacgtaac taattcttag aacaaatgtt
     1201 atcgattttg tttttcttct tccgctgttg ggatattcaa atcagacact tttatgttcg
     1261 attttccaga catttttttg ttgtttttat tagaaaaagt ttgttttttc atttgttttc
     1321 taaagcatga tcttcttgtt tcctattttg gtcagatatg gatcatgcgt gaccacgata
     1381 actaacgtac cttgggaagc ctgttgcgat aagatttcaa cgacttgctc cttatttcgt
     1441 ttatctaatg atccagttgg ttcatcggct aaaatgattt tgctattctt caataagact
     1501 ctcgcacagg cgattctttg cttctcacca ccagataatg tgtagatagg cgtacttagc
     1561 ttcttgttta tatttacttt tttcaatgcc tcatactttg ctgttcgctt atctgaaaca
     1621 tttaaattcg aaaacttcaa tccaatatct aaattaaaat cgattgtttc atattcaatc
     1681 aacccaaaat cttgaaaaag aaaagagagg gcatttcttt ttatcaagcg cttctctctt
     1741 ccagttaaat gttttgtttc ttgattaaat aaataaaatt gccctgaact gaattgatca
     1801 ttcaatccta atatattcaa taaagtactt ttccctgctc cgctctctcc aactacagtc
     1861 acaaaatccc cagcatccgc agtgaaacga tccaaatgaa gaatcgtttt gtttcgaatg
     1921 atttttttcg caccttttat cactatcaac ggctccaatt gttaacctcc attcatcagc
     1981 aataactgac ttttcttttc tgtagacaaa ataaaaacaa ctgaaagaat aaaatcaatg
     2041 aagctaaaga aaaaaatatt aaaaagatat ttaggctctc tttctataag aaaaaggaag
     2101 attacacttg tcgttcccca tttgatgagg ttcatcatga agaaatcttt atacgtttca
     2161 aagagcgaat aaccacttga acgaaagata gcgattttcc gacaattgta gacaaaatat
     2221 atgcataaca tgacatagct caacaagaag aaagaaaaga aagtgagtaa aaatatctgt
     2281 atcaagtaat gaaatgatct gcttaacact ttgacagcta tctcttcagt ctgagtatac
     2341 ggaaatgata actgcaagtt atcacgtaac tgactttctt caatcagctc aaataacctt
     2401 tctttcgaca aagagcctat cttgatcttt aacggtggat agatttctcc gctgagaata
     2461 tttctttccc aatacgtact gtttttcaat gtcagtattt caacaaccgg ataatgttcg
     2521 atccagggga tagaaggaat aaatgtataa atgggttgat tgttttttat aaatagaaat
     2581 ttcggttctt tttcactgat ttcttgataa tattctgtta tttgcgccag gtcatttttt
     2641 aaatctgtat gtctatatcg ttcagggatc aatataacag ggtgcgtttc tttttcggtt
     2701 atttggatca accttccaga gacatcaatc aaaggaaatt tcttaagata attcagattt
     2761 atttttatcc ctctgccaaa ctgttcattt tcttcattca agtaatctga tacattgact
     2821 aatatacttc cgtttttatt caaagtttca tataattcct gatcggctgc tgatgcaaaa
     2881 cgattggaat aaataaaatc cacgtggttt ttcccgatgg ttactggata aaatacatga
     2941 tagtcctcac cagcgatttc ttttggtgtt tcatgggaaa cagctaactg tgaagaagaa
     3001 aaaacgatag ttgctaattc gacattggca acggtcaaaa gaagagaaaa caacaatcca
     3061 aatgtaaaaa gaatgtattg gatatagttg aacgcttctc ttaacgaagc gattttttca
     3121 actaataaaa gagaaatcaa agagataccc tatattccgc tgaacaagaa aacgtacatc
     3181 tggaacaaat aaagaaattg ctccttataa tacataaaaa taaaaccacc aatgattcct
     3241 gcaattatga atgtaataat gattttcttt ttccccaata aacaccacaa tacttgatgt
     3301 aatgaaaagc cattattcaa caataaactg atttctttat tcatcaataa gaaaaaggat
     3361 gataacaaaa ggaataaaag aatcaatcca atagttaaat acactcgata attatatacg
     3421 tctgtacttg aaataaccga atacgaatag ctattttcaa agtcttcaaa aatattagtg
     3481 gcataatcag tgtgaaatgc ttgattgaat cgttccacaa atagtaaaat gaaccgttca
     3541 taggcttctt tttctctcgt catcaagaaa aattcacctt caaaatcttt tattttgatc
     3601 gattcttcaa tggacgttac gcgaaaggag gtattagaat agggtacctt ctcgtgagaa
     3661 gatttgacat ccccttgata atacaatgtc atttcaagct ttggctgtat cttgaagttc
     3721 caagatgtat ctacttcatt ggattcattt actgtttttt tcatataaga aagctcagtt
     3781 tctgatgaga cattttcaaa taccatgatt agctgctcat attcttcttg cccaataaaa
     3841 tgttgtggca atcgaatcgg agtataagta tctgtttgat ggaaaaattc atttgtccga
     3901 tagagtacct gtttatttat aataaccaag gcaaaaccac tcatgatacc ggtcactatg
     3961 attgtgagta aaactgtgaa cttttttttg attatcacca ctctccctta cttaaatgat
     4021 tctttgataa aatcataccg tttttcatca aaaaaacgta tctatcaaat gtataggtca
     4081 tgtagaataa atctatatac tgtagaatcg aaaggagaag aagatgaaca tcggagaaaa
     4141 aatacgaact taccgcagaa attgtaagct tacgcaaaaa gaattaggcg aaaaaatcgg
     4201 tgtttccgat aaaacaatct ctagttggga aaattctcgt acaatgccag accttgaaat
     4261 gctgtcactt ttacatcaga ctttaggtct gccgattgat tttccttcta ttgaatcagc
     4321 taccgaatca atagaaccaa cattgccgga tgaacctctt gttatcaaga aatcttattc
     4381 atcaaaacaa cccttctcac tcaaaaagac actatctttc tttctgctcg tcttttgttt
     4441 ggtctatctt tttcttatca attatcaata taaaaatgaa acggttgatc gattcaatcc
     4501 ttttttgaaa ccacaaatcg gctataccac actccctgta ggatacgtgg aaaattccat
     4561 cgaacattgg gtatgtaatg atatctttgt tcatggtaca tggctgtctt ttcacgctgg
     4621 agaggtagaa aaaggtaaga atcatgctgt aatcaaacac aaaggaaaac acgtcatgaa
     4681 cgttcgcctg ctcacttggg aagccattcc ctcagattac caagaaatcc tcatccaaga
     4741 ctatgacgat gccttaaaaa gaagccctca ggagccagat aggcattaag taggagatga
     4801 acgtagagat agaaaaaatc aatgcacatg atcttatcaa aaaaaaacag gggtacaaat
     4861 taattgaaaa agctttgaga tgaaagttcc taaataaaaa agttcagaat gataggtaaa
     4921 aaaatgacta actattctag tattaggcta tttgtattat tcttctgtta tttttatatc
     4981 aaaaaatcca gaaataacta aatataggta tttctggctt atagtataat atttacgcca
     5041 cagcccccaa tgattctttt tggaatcatg atcaaggacg gacatacaca aaaatatttt
     5101 gcccattcga tccgaataga ttaacgacta atctagtaag taatatagat tggtacgtag
     5161 tcaaaccagc aaatggaaaa gttgtctatt ccaccccaag ggctttaaag acagcatctt
     5221 ccggcgtttg ataaaaaatc aaattaaagg tacccattaa ttctgggggt acagttccaa
     5281 tatcagcagc gcttatcata ggtacaagta cttttttcgc tccggcatct tttgctactt
     5341 gtaaacagtt agctaaatta tctaccttaa tcatagaacc accaattgta atatccccta
     5401 aaataactaa acttggtaat acaggtttat ttaaggaaac tgagcataaa gctattatag
     5461 ttgataacga taatgttttt gtcataccaa tgccattcat atcttgaaca tgaacgacaa
     5521 aatcttttgt cgtcaaacta atagactgac taacacttcc ataattagct cttaaatatc
     5581 ggtatgccga atccatcgct tctcttgctc cagcatctga attgatccca gtacgttcaa
     5641 actttccatt tcccgaagtc atttgcgttt ccaatttata ggtacctaat tgcccagttt
     5701 tgccataaga taccgtgtac aaatgccctg gcttccctaa cccttctgga atcaaagttc
     5761 ctccaccttg ttcaggaaca gaaacatact cttctcgctc ttcttctaaa tcaatgtatg
     5821 aaaaattgac atcataaaat tccattccac caattttctt taattgttct tttacacgac
     5881 gacgcatttc aagagcaaat cttagtattt cttcgacatc acttttttca aatctaccat
     5941 caggatacaa cagtttcatc atcccagata caatccgacg aactgcaatc gtatcccgct
     6001 gatttaattg agaaccaagt ttgaaatatt tatcaaaact atcgccaaaa ctaacttttc
     6061 gaagctcacg catgacttca gaaaaataat ctgtaatgaa gccatagtca tttgtaaaaa
     6121 aatctggtcg atatttagga atttcccaac ctggtaaata acaatgcatc cgatccaaaa
     6181 aggctgaatc cgtccccata acctccggaa atggctcaaa taaattcgaa gttttcaata
     6241 ttacatcaac gctttgatta atatttccta caaaagccat tgatgctgaa gcattctttt
     6301 cttctttgcc tctagcaaaa gatcctgaag ccatgtaatc tttcatgatt tgaacgccat
     6361 cattatcctt aaatttaatc ccagcaactt cgtcaaaagc aacacagtcc cacataccta
     6421 caagtcccat tgtacgacta gccatattat agaaaaggtt tgctactgtt gtttgtccac
     6481 ctgaaacaag gattgagttt ggtgaaattt ctttatatac atgcgattta cctgtaccac
     6541 gtggtcctag ttcacagaga ttaaaattat tttcaattaa tggaataagt cttgctaaat
     6601 gaagccattt taccctttta ttaaattgtg taggttccat accaatggac cgtagaagta
     6661 agtcaatcca ttcatttgta gtaaactcct tgcgagccat cttgtaagcc tcaatgtcta
     6721 aaccaggcat ttggattgga tcaacctttt ttgcaataaa agggctattc caacgatcat
     6781 tctcatcata ccaatattcc atcgaaacaa tacaccagat ccccccacct aataatcgat
     6841 caaatttttt cggatactct tcactaattt gaacattttt taatcccagg ttagagaatt
     6901 ctgcttcata acaatctttc ttttcattta aatgtacagt tactttatca ataactgtat
     6961 aaccacccaa ttcacgaatt tttgctttta ctttttctgc ttcatcagga cgcacatagt
     7021 ttcgagcaag aatattttta acattttcca cacctttttc aaccaatgtt tcatccaatg
     7081 acgaagcata cataccaagt aaatattcca atacataaac aggtacattc gcaccttctt
     7141 taattttctt tgttaaatct tttctgacaa tctttccggg aaagaattca gataacttta
     7201 aaatttcctg ttgttccact agaattcctc catgtgttca gtcattataa tagcaattaa
     7261 agtatatcat acttaaccag taggcttgat aatacaaaag aaaaagtatc cacaaaaaat
     7321 tgtggatacc tcgtttttat atatcaaaat caaatgattc tgcaaaagga ttatctataa
     7381 tgaattttat tcgctcggtc aaatcatttt tttgattttt tatcactaaa taataagtat
     7441 cttcaactgt atatcgacga tttacaaatt caaaaacaaa tttagtaaac cgctgatttg
     7501 catcttctgt ttttgaatcc gcaacataga tttcttcatt tgagatacgt tcaccatatt
     7561 catcttcaaa ataaagccag aaagatgcgg ggtcataaac atcactaatt gcattttttt
     7621 gatagaattc taacgtggtt gataatcctg taattctgcg gttgctagtc attaattcaa
     7681 ttgctactgg ttcctttgca ttgctacctt tggctaccgt aatttctaga acagggacta
     7741 gcatttcttg aatagatgac cctccatgaa cgtagctttg tcccccgcca gctttcttaa
     7801 aaatacttga agtaatcggg acacaaatgt ttctagtgtc atcatttcct aaagaatctc
     7861 ccaaagagta atttttcgta ccaattattt cgtattcttc ttcactaaga ataaaacgac
     7921 gttctacacg atctttttca tttctagatg gattttcaat cttatctact tcttcaacgt
     7981 ggcttctttt ataaataaat ccatgatcag ccgtaactat aaaacgatag atactgccat
     8041 cattatgcaa gcgattaata agtcgggaaa tttcgcttat cgctaaatca caggcctcaa
     8101 aaactcgatt ttcattcgag tgatcacctg ttctatccac ttgatcgtga taaatataaa
     8161 tgactgattt gccattaaat acttctcgta cctcagcctt attcatctta accacatcat
     8221 cataatttaa agctacagca tttgcatctc gttgctggag aatcgcattt cgattggata
     8281 aaccattcgt ttttttccca tcaatcagta cttctgttcc ttcattgtaa gttagttgat
     8341 tgtttggtaa taaggcggct ttaccgaatt cagtaactga aggtaataca gaaagaaagc
     8401 tagccatgtt tgttgaatac ttcttttctc taactaactt acgttctaaa ttcatcccta
     8461 actcatatcg aaaagcatct gaaataataa ctacagtttt aacagagcgt ttcattacag
     8521 cttgattata aaattttcga atggatggac gattcttaaa ttcaaaagtt tgattccaaa
     8581 tttgtcctga ttgatcaaga aacttcgaat aatttgcttc aactaatcga tacaattggc
     8641 catatttttg cttttcttct atatgatcac tattccaaat aaatttccga taatgcgtat
     8701 caacccaata catttccttc tcatattgag ttagcaaatt atccatgttc atcggcaagc
     8761 acaatctgtt tttatccaca agataataag catgtttcaa taattgatac tcataaatat
     8821 aatccgatgc gaaatgcatt ttttcgcgct gctttaaact atcaaaaatt gtttgtcctg
     8881 caattttcgt tgtagtgtca gaagccttta atcgttctgc ataaaacatt aatatttttg
     8941 catgaatctc agaaaatacg tctgcttcaa ttagatcatc aatttctata ctgtctaata
     9001 atccatcacc atcaatagcc tgatatactt ttttagatag ctgttcaaag ctttccatgt
     9061 aacgtgtatc attcataaac tgatccatga aagtaataat gtttgctttc aaatgtagta
     9121 tttcaaatcc tttgaacttc ttcggcatct cttgatcaat ttgataataa aaatagttca
     9181 aataaagaca catcgtcagc ttttccaatg ttggctggct atccgtaaag ccaaatttca
     9241 tttgaataaa ttcccaaaat ttagctgtta actgatactt atcaagttcc cttaaaggat
     9301 tctccctact ttctgtaaag ctttttagaa ctacacgcag taaatcattt aatcgaatac
     9361 ttttcgattt caacaaaaca gccattatca ttaattcaat cgtttctgat ttattaattg
     9421 tcatatgcgt actaaattca ccaaaacttc tcatgcgatc ctttgcatta aagaaattac
     9481 gatactgttt aactgtctga tgaaatctaa gtggaatagc caattcattc atgataatcg
     9541 ctaagcggtc tgcactaaat tcctctgaat aattcaatac actcaacaaa tgattatctt
     9601 catctttatc atcccaacga ggaaatggcg catagattaa atagttagtt tcgggatctt
     9661 catattccaa taaacgctta gttttaaatt gtgcgtcctt ttctaatcga tagatttttg
     9721 cattttgaat gaccaatgag tcaatttctt caagaaaatc ctgatttgaa tcaaaccaaa
     9781 aaatgatttt cctacatcca taattaggaa aacgttgatt taatttttct tcaatttgtt
     9841 gcgtatttat atctgtcatc aatctcacct aatcgttctc tttctatacc ccttatattg
     9901 acataatttg gataatttcg cacgcaattt aagaataaaa aagaaagttg ttagaaaaca
     9961 actttcttag ataactattt ttttggttct ttgacccctt ttgcaaaaat ttggaatttc
    10021 tcgccggttt taggatcacg ctgcaactta tcataattga caattacacc atcatctaag
    10081 tctaattcaa ttcgttttaa tgctaagtga cccaacttct cgtcatactc acgaacttct
    10141 tttaattgct tctgaatctt tacaatttct tttgtcattg catttctttc ttttgggtta
    10201 tcacttgttg aaatttgttg ctgacgcaat tcgattcgat tgtcatacgc tttttgtagt
    10261 tcgtgtaggt attcagtacg tacttttcct aattgatctg gtgtatagcg atgcaagtac
    10321 attaacgctt taaagccatt ttgttttcct gagtccaatt gccaataaat tggtcgattg
    10381 gagtatgttt ttaaatggtc tttgtaaaaa tcttgtacga agtaacgacg aataatttct
    10441 cgacttgtcc ctttgccacc taaagtgtca gcgataaact ggagattttc ttcaagggtt
    10501 tctttaccaa aagtaatctc aacgaaatca atgaaacgat tgacaatgtc aatttggcta
    10561 tccttgaaat actcatcatc ggtgatgagt aaaacattat cagtatcagg tttaaatttt
    10621 tgatagcggg aaggatccca ttcgccgcca gcgaagatga gaccatcttc gtctagggag
    10681 taacgaccga agatacaacc tattgaataa gaaataaaat ccttaatttc cctcgcctta
    10741 tcaggtaacc ttgcagagat atattcatct tgaacctctt ttgttaattc tttttcaaga
    10801 gaataatgat taatgaatat gtcgttcagt tcctcttcat tcgattttag agtattaaat
    10861 tgattaacca actgcctact tagacagtta aatgcctctg agagatcttt tttaaacata
    10921 taacttaaca aaatgtttct tctaaactcg tatgacgttt caagagcatt atagtctttt
    10981 ctagctatat cgatattttc atccactttt tctcttattt tttttaattt tctctcagat
    11041 gtaactttaa gaaaaggtag ttttcccatt ggtccttcat ggtaatccaa ggtgggagaa
    11101 ataaaagtta aaaagtgatt aactaattta gagtttacat agccaaatat ttcttcaaag
    11161 tcagttatat cctttgagaa cagaacagat cctttagttt caaaaattgc ctgattctgc
    11221 aatctaaaag atacttgtcc agatgaaagt gtcgaccaag taattccctt tttaaaatag
    11281 taattaagat tttgtggtct agattttaac ttcccatttt cattaacata attttttatt
    11341 tcatctccat cattctccca gttaaccacg tattcattgt ttccatacca ttttctaaaa
    11401 cgaccacctt tagttgtagg aaaccatttt tttctagact ttttagcgtc ctctaatgtt
    11461 ttagcatcaa actttatttt gttaaattct acttcaaacc aataccgcaa aaatttattg
    11521 ttatttccgg ttgccaaccc ttgttttgca tctgcaacat cgttagttaa ttttccttga
    11581 gcaaaatcag tgattacgtt atcgcttgcc cagtaagcaa tcggcattcc tgggattttt
    11641 ttgaagttgt cttgattagt actataaaaa taatcgcatt caccatgctg atgaattgct
    11701 tctaacgttt taattttttg aacttccatt ccacctttaa aatctgataa ttttatatag
    11761 cttccatctt gttcatttga attttttatc gtaaacgtac aaattggaac ggttgcttct
    11821 tcaaaagctg aatactccat ttgaatcaaa ctagaaatgt ttctttcatt aattaaaaat
    11881 gagcgtaact tttcatagct agaaatgaac atccaaacaa atggcgtcat aaaggaagca
    11941 tatccattat caatcagcat ttggctattc aatttaataa acacagaaaa tagatctttt
    12001 ttgacatcag aatagttatc atttacatat ttttttaatt tcttatccat tttattaaga
    12061 taaggcggat tagtgactac cgctacatat ttatcaacta gcatttcagc cacgtcaaga
    12121 atgtgcaagt atttttcttg tatttccttc atcccataaa gaatatccat attcgtaaat
    12181 tcgttgaatt ttgatatata ctctcttact tttcctaagt attctttagt tattgcctga
    12241 ttatttttat cgactaactt aatgattgat ccaagttctt tcccattttc aaattgatca
    12301 aaaattaact ctttgtattc attccagcgt tcactatact tatcattgtt caattcacta
    12361 atacgctctt gatactcgtc tgtcacttta ggagaatcaa taaactctct taaattcggc
    12421 gatagacttt ttttcaaaaa aagacgatcg tattgacgcc ctttcatcat aattgcaaaa
    12481 taagacaatt gatacgctct tttatcgatt tcaagaccat ataaattgta ttcaacgatt
    12541 gcacgtgcag catcacgctc agaatatcct aacgtaagat aaatttccat caatacatcg
    12601 aaggcgtaaa ctaaaatatg cccagacccc attgcgttat cgataatttt tagttcttct
    12661 ggttttaaat tacttacaga tgttgcttgt tcaaaagcat atttatctgg aattaagtat
    12721 ttcaacttat ttcttaattc actattggga taatgatcta accaatactt tcctaaacta
    12781 ttgtcaacca tataacgaac gacccaatct gtggtaaata gttgagttgc tgccggaata
    12841 tcttgttttt tgacaatccc tttataaata ttcaccactt gattatgtgg ctcactatta
    12901 tagtactgat acaaccaccc aataatctct acctgtccac cagcttgaac atagaaatca
    12961 tcctctggaa tacttaaaag atcagcgatt acaccatctt ttttaatata agaagctgta
    13021 aacaaaagtt ctgtataatc ttctacttct tcaaatagct caggtaagta atcattcaat
    13081 tgattacaga tttttataaa aatcaattga tacagcttgt ccattgcttc tgctgaatta
    13141 tctgttttcc aagttctgac ttgttgctgt tcattactag ataattcttc aaagatatcg
    13201 gcatcataaa tatctgtaat aatatctggc tcaattttcc cacttatttc actagataat
    13261 acacgatacg tgtcaggtaa ataatcattt acctccataa accgaatggc aatcaatcgg
    13321 ttaaaccacg tataagcaac ctcttcgatt aactcttgaa aagcttctga ataagaagtg
    13381 acagaagcac gttgttttag ttctgcaatc aatttgtttc tttgcgctat ttcttttcct
    13441 tgaattctta ttcctgattt ttcgatttct tgtaaattgc tatcaatttt cttcacatct
    13501 tcaatttttg attcatcaat tcctaaacgt tttgctttag tcattacttc atcaattaat
    13561 tttctacggg cattgaccgc gaaattcttt atcgctttct tatccatttt tctttccctt
    13621 ctatatgtaa cctttgaaaa gacaggcacc tttttatgcc tgtcttttca ctagaattga
    13681 atcgtgattt ctgtattttc ttgaagttgt tccttcagtt tttgattaat ttcagctgtt
    13741 aactcatcaa tatctgctgc tgacttaata gttttaacat gaacgttaag tgttctcatt
    13801 ggtactgttt tctgttgaat agtaggtttt actatcgcta tttcttcagc ttttgctgca
    13861 gagtctattt catctttttc agtttcacga atcaagtttg ctgcttcaat ttgtttacgt
    13921 gcttgttctt cttgacgtct gcggttttct tcattatcga aacgttgatt aaagatcaaa
    13981 tactgttctg ctacgtttaa tgataagaaa acaagatcat ctatagtatt cgcttgttca
    14041 atttttgctt tcagttcttg aaattcttgg tcaactattg gtacaaattg atccttaaaa
    14101 tcttttcctt ctaataattt aaatgttgct tgtttttctt ccgttaattt atttaatatt
    14161 tcctgacttt ccaactctaa cagttgatta tattgttcaa taaattcttg aatcaactca
    14221 tttagtttca tcatatctga ataaggatca gcctttttca aaatggtttt catctcatga
    14281 atcaattgat caatttcttg gctagaagtt tgacgccgac ttttttcgat taatctaatt
    14341 ttatcttgtg cattctccca gatttttttc tgagtactat tttgcttgtg gaaattttta
    14401 attttatcat atgtttcagc ccagtcgaat aattcatcgc gatatttttt gattgtataa
    14461 aaaaagtctt caacatctga cgtttgaaca attacttcaa gatatttttt tatttgctca
    14521 tattcataag cactagggta ggtataagtg ttttgtaaat caaaataaga gcgtaaattg
    14581 tctaattgac cttttaaata tttcttgaaa ttttccattg tatgttcatt gttattttca
    14641 tcaacaatat tacgactttg aaacagttct ctaccgattt cgtcaaccaa tttttttgct
    14701 tttggcgaaa tcaccgcgct tggttcaatt tttatctttt cactttctcg tcgtttttga
    14761 ataatcatta caatactatt tggatcatcc atccgtgaaa tttgtacatt gttataaagt
    14821 aaatcaattt taccagacat gaaaagttta gcgatgcacc attccacatc aagttctgtg
    14881 aatccatacg gttgttttgt ttcaaaacga tcacgaattg ttttcatcgt aatcgttagg
    14941 tgatttctct tttgatcatt gataaaattg aaaatttcct gaactgcttg ctcatttgat
    15001 ggatcttcaa taatttcatt tttgctttct ttcactaaat ataagatatc ttctttttct
    15061 ttaggcgcat caatttggtt taatttatgg tatacttctt cagccatttt ctgaagtgct
    15121 gattggaatt ttgctttaaa gtcggagcct gtcagttgaa tttctgcacc gttatagaaa
    15181 aattttgcag atttcaacag ttcatttaat tgatcgttga tacttgcact tagttcctgt
    15241 aattcaccag atttttccga acgaatcgcg tcaaagttct ttactacact cgaataagtc
    15301 gttgttaaat aaagattcat tctagcatac attgctatat catctttaaa ttctttatct
    15361 gatggcaatt ctacgaataa taagttacgg gaactcttaa gcgcaagttc tgcctcttga
    15421 cctgctaaat cagagtatgg tgaaataaaa ttaactgtca tttcagcatt tccagcttgc
    15481 ttgtatggac gttgatctaa cacttgtgca taagtaaacg tataccggtt tttaaattta
    15541 tttccacctg acatgcctaa tttttcatag gcaaaactat ttcggtctag aacgccgtca
    15601 aaaattcgtt tagatagttc tacgatcaaa tcactatctg taatattttg atttttaatc
    15661 tcacgagtaa tttcctgttc ttcatcagtt tggaaaatat aactatctaa gttcttccgc
    15721 acaaagtttt ccttaattaa aaggtccaat gcttcttcta ctcgtttttt agtttccagg
    15781 cggtcttcgt tgatatttct tatcatcaag ctcgtaatat tttcaacatt tggtttgatg
    15841 gcttgatcaa catatttaat catgaataaa attcgtaaga catttacgtt aaagttatct
    15901 atatcagttg gtctttgaat atgagaatta tttgtagctt gtgtaatcac tcggctaatt
    15961 gctgtatcaa tccaacgttc taacgagtaa taaaactgat ctaaagaaac caaactggtt
    16021 gtatcatttt ccttatttcg ttcagcggct tctttaaaca ttgctagtaa tgaacgttca
    16081 ccagacgata agtttgatcc ttgatagctg tgattacgaa tctcggttag aatttgcccc
    16141 aataaattga attgataggg aataaatgga taaacttctg cgtaattttc agcatcttgg
    16201 aagagcttta attcaggact atcaacaaag agtaatttat ttttcaattc tgtttgaaca
    16261 gtttcaaatt gtaaggctaa agaatcattg gcaaactctt ttttcttcaa aatacgttct
    16321 ttaattactt catcggcatt tgctgaagat aaactcacag ttgtggcaaa acgatccttg
    16381 atcttagaaa aatcattatc agaattgtta tcaaagtttg ttacgtgatc aatcgcttcc
    16441 tgacttgtca ctaataccca agccttacct tcacaaattc gacccaaatc ttccacaacg
    16501 gtttgtaact gcaaagtcaa ctcacgatta ccgccgatat attgtccgac ctcatcgact
    16561 agaaaggcaa tatgatggtc tgcttctttg gaatcaagat agcttttaac tagatttgca
    16621 aagtcatcaa tgcttattaa ataatttcct gatgcttttt ctaaaaaatt atcaatagcg
    16681 gcttcactca taaaatcgat tttaagtgcc gcttctttga tatcatcttg gatccaatca
    16741 aactcatggc gctcttcttg ccattttgcc ccattaatct cttcaaaagc agctttgaat
    16801 gcatcaaact tttcttcttt aattaaccga cgttcaaaat ctgctagatg tggaatcgtg
    16861 cttaatcctt gcatttcgtt aaataccttt aaaaaaacat tcacgattcc gtttttgtct
    16921 tttttaccac ctgcatcact ttttgaatca atattaaaca gaataacatc tgtatttatt
    16981 tgtgagcacc gttccatcgt tgccaaagtc agtggatctt tgattttccc atcttctttg
    17041 aagtaatcaa tggctttctt gtcatttatt tctcgatttg cgagcaagta agaaataatt
    17101 tttaagaaat gagatttacc tgaaccaaag aacccctgaa tccaaacacc cattttatct
    17161 gttggtgtat tgatactccg ttggtaggca tcaaaaattg ttttaaagtg tttttgtagt
    17221 tctttcgtaa ccacgtattc ttctaattct tgttgaacat tttcatcctt tgcttgaccg
    17281 accttaataa ctccttgaat atttcggtca attggttttg caaaaatatc tttaattagc
    17341 atttaatctc ctaccttcca tcccaactaa attctaaatg ctcgataata attatcatct
    17401 ttattggtat taagaattgt caaacttaat tcatcatatt cccctggata catcatcaca
    17461 actggtacgc gatcaaatac ctgatgcatt ttatttaaaa tagagtgcgc tctaattaat
    17521 ggatataatt cgccaattcc tgtcaggaac acaactgatt tttctggtgt atgggcatcc
    17581 acatattcaa aaaatacatt ttcttcctca ggtaaatcca ttttcaataa acgaccaatg
    17641 ctttccacta atttttgtaa accacgtcgt tcttccatct taatcgcttt ttcagtgaaa
    17701 ccgcgttttt ctagatactc taacataatc acatagagat tataaacttt cacttcataa
    17761 ttatcaccaa cagatgttcc agatatatca ttaatataat ctcttacaat taactcgtct
    17821 ttcggatcgt agtcaaagat ataatagcct acttcattac ctaaaccacg attcaataaa
    17881 aaatcttctt tttgaattac ttcattcaac ttttccaaat gctcttgaat cgataatgac
    17941 attataaaat tcctcccagt gctagtacaa tatctttacg attcttgtca actaaccatt
    18001 gaatcaatcg tttatctaat aatatcggag tcattcgtcc atattctttt tcccctctga
    18061 ctaatcctgt ttcaattaga ttcgtttgat aagcggcaat aagccgttta atcgtataat
    18121 ctttccattt tgaaatatct tctgaacttc tccgcttctc tgtaaaaaaa gaacggtaat
    18181 caactggtgt taattgcaaa tttcctttac gtagattttc agcatatacc tcagtcataa
    18241 attcattaaa aagatcatca atcataagga tggaaatcaa attcactaac ttttgattat
    18301 ctatatttaa ctgattgaaa agttgcaatc cagcttcatc cagttgacta actctccttt
    18361 tcacgttctg atagatttct ttttgacggt tactgctcac tgcaaaaaaa atattttcat
    18421 gttcattttt ctcttta
//
LOCUS       DAFLWQ010000056        18262 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.057, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000056 DAFLWQ010000000
VERSION     DAFLWQ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.057"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(168..1676)
                     /locus_tag="L1V16_001910"
     CDS             complement(168..1676)
                     /locus_tag="L1V16_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBN1276249.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            1835..2026
                     /locus_tag="L1V16_001911"
     CDS             1835..2026
                     /locus_tag="L1V16_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276250.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            2229..3146
                     /locus_tag="L1V16_001912"
     CDS             2229..3146
                     /locus_tag="L1V16_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HBN1276251.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            3139..4212
                     /locus_tag="L1V16_001913"
     CDS             3139..4212
                     /locus_tag="L1V16_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276252.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            4360..4878
                     /locus_tag="L1V16_001914"
     CDS             4360..4878
                     /locus_tag="L1V16_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276253.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            4859..5251
                     /locus_tag="L1V16_001915"
     CDS             4859..5251
                     /locus_tag="L1V16_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HBN1276254.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            5327..6262
                     /locus_tag="L1V16_001916"
     CDS             5327..6262
                     /locus_tag="L1V16_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HBN1276255.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            6395..7174
                     /locus_tag="L1V16_001917"
     CDS             6395..7174
                     /locus_tag="L1V16_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBN1276256.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            7167..7484
                     /locus_tag="L1V16_001918"
     CDS             7167..7484
                     /locus_tag="L1V16_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBN1276257.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            7728..9338
                     /locus_tag="L1V16_001919"
     CDS             7728..9338
                     /locus_tag="L1V16_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1276258.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            9495..10343
                     /locus_tag="L1V16_001920"
     CDS             9495..10343
                     /locus_tag="L1V16_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBN1276259.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            10574..11053
                     /locus_tag="L1V16_001921"
     CDS             10574..11053
                     /locus_tag="L1V16_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276260.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            11086..13314
                     /locus_tag="L1V16_001922"
     CDS             11086..13314
                     /locus_tag="L1V16_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1276261.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            13443..15086
                     /locus_tag="L1V16_001923"
     CDS             13443..15086
                     /locus_tag="L1V16_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBN1276262.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(15159..15704)
                     /locus_tag="L1V16_001924"
     CDS             complement(15159..15704)
                     /locus_tag="L1V16_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HBN1276263.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(15727..16212)
                     /locus_tag="L1V16_001925"
     CDS             complement(15727..16212)
                     /locus_tag="L1V16_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBN1276264.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(16202..17014)
                     /locus_tag="L1V16_001926"
     CDS             complement(16202..17014)
                     /locus_tag="L1V16_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HBN1276265.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(17153..>18262)
                     /locus_tag="L1V16_001927"
     CDS             complement(17153..>18262)
                     /locus_tag="L1V16_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBN1276266.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT         5945 a         3317 c         3646 g         5354 t
ORIGIN      
        1 aaattttcat tactttttta gagtgaaacg cattcatttt ccattagaaa ataaagcgaa
       61 caaaataaaa ggtttaaaaa gtgtaacgtc ttagtaaagt ctataaaaaa acgaaactat
      121 cgattaagct aatagtttcg ttttcaacat ttataagtaa actttttcta ttggtaatat
      181 agattttcgg aagggtagac aggtgcgcag gtaatatcga ttcctagttt tttcaatgtt
      241 tgttcatcat ttttattgac catcacagta gagtgggctt gtgctccctc aagttcagct
      301 agtttatcat aagcaacttg agcgattgga ttcgttactg cactgattga taaagcgatc
      361 aagacttcat tgatgcttag tgcatccaaa gaggaatgaa gtgtctttga tttcaatcct
      421 tgtattgttt caagaactaa tggtgacaat aaaggaatgt catctgcgat atgggctaaa
      481 tgttttactg catttaagat aactgccgct gacgcatcca tcaatgaact tgtacgcccg
      541 gtaatgatga cttcatctgg taattcgatt gcaatcacag cagaaggatc ttttgtagga
      601 ctttgcgctt gaatcttatc tgcatagtca tgggcaggga ctaccacgtt tcggtcttca
      661 ggacgtaaac cgacttcttc cataatcagt ttgattcgat taactgcttc ttcgtcgatc
      721 aatccttttt tgaagtcgca ttctgtttgg aaataacgac ggatgatttc ttgtttagag
      781 gcttcttgga caacggtatc atccacgatc ccaaatccta cacgattcac acccatgtca
      841 gtaggagatt gataaacaga ttctttacca gtaatttttt caataatacg tttgattaca
      901 ggaaatgtct caacatcccg attatagttc acagctactt tattgtaggc atcaaagtgg
      961 aaggaatcga tcatattgac atcttttaga tcgactgtgg ctgcttcata agcaatgttc
     1021 agcggatgtt tcaacggaac attccatact gggaaagttt cgaacttgga gtaaccagct
     1081 gcatgtcctt tttggctttc atgatacagt tggttcaagg aagtagcgag ctttccactt
     1141 cctgggccag gagctgtcac tacaacgatt ggtttagttg tttcaatata ctcatttttt
     1201 ccaaaaccat cttctgagac gattttttct acgttgactg gatagtcttc gatttctgag
     1261 tgtttataga ccttgatgtt tcgtctttct agtttattga taaagacttt cgtggcaggc
     1321 tgtccactat agcgagtgat aacgacactg ttgattaata agccataacc acgtaattca
     1381 tcgattaacc gcaagatatc catatcataa gtaatcccat aatcaccacg gatcttatta
     1441 cgttcaatat ctccagcata gacgcaaatc agtatttcag cttgatcttt caatttttgc
     1501 agcaatttga ttttcgcatc ttcttcaaat cctggaagta cacgtttcgc atgcttgtcg
     1561 tcaactagct tcccaccaaa ttctaaatat aatttgtcat agtggttcac tcgttccaaa
     1621 atatacgctg actgctcttc aatatatttt tctgaatcaa aaccaatttt tttcactagg
     1681 ttccctcctt aagtactaaa gcattttttc atttttttga ggattcgtca actggaagag
     1741 cgaaattcct caaaaaaaca aagaaaatgg tttaaaccaa cttgtctaga tagttattca
     1801 ttggtatgat agtttttgat aaggaaggtg ctacatgaaa aaaagacaga aaaagaaaaa
     1861 cgcatataaa cactatatcc gttcgatttt taccggttat gaaagaatgc ttgaagatcc
     1921 cgaattggaa caattgacgt ttacttatct aaacgaagaa acgcagctaa ctcgtgatga
     1981 gcatcagcgc attcatttca caacaagaga tctgcctagt aaataaaaaa taagataaag
     2041 gtcatcggat tcgattctgt cctatcagat ggaaagacta gttgatcgaa aaaaaggctg
     2101 taccaaattt tggtgcagcc tgttttatgg agcattgccc gctctttttt ataacaattt
     2161 tttacagaaa atggtactat tgaagtatta ataagtgaaa aacagatgag taagaggagg
     2221 caagtagtat gaaagagcca gatacaaatg caaattatga gccagacgaa ctagaggaga
     2281 cgaatgcgga tcaggataca ggacaagaat cgtcttcttt ttacgatatc aaagaaaaag
     2341 caagcatgaa tctttcccaa ttattagaag acttacaggc ttttgaaaaa gctgtccgcg
     2401 aagaagatat ccctgagatc taccgtttat acaatggccg attgaatgaa gaattaaaaa
     2461 gaagctcaaa tgaaaatcac gagatcgatc aattgctgat gcgtaagatc catgatcgtt
     2521 ttttacagga atttcctttt atggaacaag tagaaaacat ctcgccaacg atgagctatt
     2581 acaaaatcgg cacttattac catgatcggc ccacggtcgg tattgatgca agtctgccag
     2641 aaatttttgt tttgcctaag atcgatgaag agtgggagaa atattcccaa ccggagtcaa
     2701 cggactatga caaaaaaatc aatgagctag acgcaaaggt gatcactgct cagacagaaa
     2761 ttgaacgttt agatgaacaa ataaaagaaa tcaatcgaca aatgactgat ttgaacgaca
     2821 ataaaggatt cttgaatcgt aaaaaaatcg aggaagaaat tcaagaatta gagaagaaga
     2881 agcaagtact atctaatgaa aaattaggct ggcttcctta tattgagacg cctgaaacaa
     2941 tccagcagca aaaagaagca ttgaagcaag aagcaagagc agaccagctt cgtgcagcca
     3001 tcgtagaaaa agaacaaagg caaatcagac gctatttcgg tagcaaagag ggattcggtc
     3061 aagcaatcca tgaattcttg atgaattatc ttggcaatga gaatcctaat aatcaatcta
     3121 atgaaggagg ttccgagtat gaatgaacac gatgaagcag aatggacaaa aaatgaagaa
     3181 caaacagaag atcatgaaga aacgaacact tcattggaag aacaaacaag taatcctctg
     3241 gatgacacag aagaaatccc tatgctagag gaaacaaaaa tacacgaaaa agaaaaagta
     3301 actccgacga atacgaatac tgcagaaaac acccatgctt acgaaataac tgaaaatccc
     3361 gggtatttag aaggaaaaga gcaagatcat caagatatcg tcagtttgat tgaaacagcg
     3421 gaagcagaat tagcggattt acgtatgaga aaagatttga tcgaatcaga ttttccacaa
     3481 ttattagaat catatgatcg ttttatattg aatgaagaac caatctccac gatcggaaag
     3541 acaagcctga tcgaatactt cacgtatgaa ttactgaaac cgttgaatga tattggtctg
     3601 gaacggtcaa attcagctta tgacacatgg aaaacaagac atttttcgat caattatacg
     3661 ttgaatggac aaaacgaatt agtcttttcc tttgtattac cgaccatcga tcaacgatac
     3721 caagtggaat cgatgagtct cctaaacgta tcaccagaga caatggaaat caatgtccaa
     3781 gatgaccggg tgctttcttt gatccgacac tggtcagtgg atcgagtatt ctctgcaggg
     3841 cagatcacga tattcaatca caaattgaat caattattag cccatgcaag aacacttggt
     3901 tttaccgtta atcagacatt actagacaat acgaagccac ttcgtttgaa tcttcagagc
     3961 gaatttgaat tgacgaatga agtattggat gatattttta tcgtggcaat gaaaaatcca
     4021 tcctacgata tggaaaagat caacgaaact acttatcaag tacgattaga taaaggacag
     4081 tctttaacga taacaacaaa cgaaaaagat caaacagtct tgtcgatctc atctggagac
     4141 tacccacgat ctgtcattga tttctttatc aattacgaat tcttggtccc attaatggtg
     4201 agaaagtcct gattggataa gttggattac cagatgtcat tcagataatt ctgttccaaa
     4261 ggacttgcgg cagttatcca gaataattgt cacaagtctt ttctgtatgt actaaatgga
     4321 cgtgaataac ttgctgatga aggagggatt tcattaggaa tgtccacaaa taaaatagca
     4381 cagcttagct tattgtctgc tgcttgtgta gcaggtagga tcgcttttca atttattccg
     4441 aatttccagc caatgactgc tattttttta tttatagtac tttacttaag cttaaaagat
     4501 gcgttaattg tcatgagtct ttctattgcg atcagcagtt tttattttgg tgttggacca
     4561 tgggtcatcg gccaatggat cagctatact gttgttctga gtttgttttc aatcgtctgc
     4621 ttgagaaaaa cagtgcaaag gaatctatgg ttaaagggag tctgtttttt tctggcgggc
     4681 atggtttacg gaataggtat gaccgttttt gatacgctgt tatatcgttt gcctcaacct
     4741 tggatctatt accttcaagg ggtgtcgttt gatttgatgc acagtatagg caatgttgtg
     4801 ttctttcttg tttttctgcc agtcgtcaaa cgtttttaca atcattcagg aggaaaaaat
     4861 gaaaaaaata atttatagtt tgcttgcaat gagtgtcagt atactcattt tgacaagttg
     4921 cagtacaacc tatacacaat cggcttccaa ccaaaaggag gaagtaaaaa catcgcaaaa
     4981 agcaacaatc acgttacaag aaaatggtca aaacttttcg gaaaaagaag tgttcttcaa
     5041 aaaaggcgat gatttactga gtattttgaa acgaaatttt gaagtcaaag aagataacgg
     5101 cttcatcact tcgcttgaag ggcactcaca ggatgagaaa aatcaactct attggatgtt
     5161 tactgtggac gggaaaagtg ctactactgg tgccaaagag atcaaattga atgatggaca
     5221 atcggtcatt ttcaatttgt ctaaactata agtttcataa aaaactgtta aagggcgaat
     5281 attgccataa ttcagtgagt tcagttgatg aaagaaggaa aataacatgg aaaattttaa
     5341 aaaaagcgga atgttttccg taattgctgc tctaggggct aatattctag ttgctatcag
     5401 caaatttgtc ggctatgcaa tcagtggcag tgccgccatg ctaaacgaaa gcatccacag
     5461 tatcgttgat tgcagcaatc agattttgct gttattcggt gataaacaag ccaataaagg
     5521 acagagcgag ttgcatcaat ttggtgaagg acgagcaaaa tactttttca gtacaatcgt
     5581 cgcaatgatg cttttcttcg gcggtggggc acttggggtg atggaagctt ttgaaaagtt
     5641 gacgcatcca tcccatgaag tgggtaatcc gatcattgtt atagcaatac tgttatttgg
     5701 tttggtaatc gaaggaagtt cgttacgcgt ggcaatgaaa gaaatcaaag aattgaatac
     5761 tgaaaaactt tccacgatgc gctttttgcg cgaaagtcga cacagtgaaa tactgattat
     5821 ttttacggaa gacttgtgtg ctgtaatcgg tttggtcttg gctttagcag gaacaatatt
     5881 gacttatgca accgggattg ctgcatttga tgcgatcagc ggattgctga tcggtttctt
     5941 gctgatggga gccgccattt tcctagcaaa agaattttat agtctgatca tcggtgaaag
     6001 cgtgacagca agcgatttat caaaaatcaa gttagctttt gaacgtcctg agatcagtcg
     6061 gctgatcgat ataaaaacag ttcatttaag tccaacggag attttagttg cagcaaaagc
     6121 agatatcgtt ggtaacaaag agaatgaagc ttactcggtc atcaatgata ttgaaaaaaa
     6181 tatgcgtcag tctcttcctg acaagaagat gtatatatac attgaaacag ataaatatga
     6241 cccaaattat tctcgtaaat aaaacgttta ttcatgaatt gaagcaaaaa tgagaaaaat
     6301 ataatcttgt ttttaaataa aacggctaca atttagcgaa tttatgttac aatgagtccg
     6361 ctgtttattt gttgtaatta aaggagatat tttaatgaac aaaaagaaaa gtgcgccatg
     6421 gcttcaagct ttgcatgcag tgatgccact ttgtataagc tatataccag taggattagc
     6481 ttgcggagta ttgttgcaaa aagttggatt tgatcctctc ttatcaggac tgttatcgat
     6541 tctggtcttt tccggtggcg cgcagttttt agttgcatct atgcttacga cgcaagcatc
     6601 atttgcaacg acattattga tggttttctt tttagaatta cgctatacat tattaggagc
     6661 aagtcttgcc ggttttatga aaaaagaaaa gcggacgttt ttggctgtct tttctcaatc
     6721 actgaatgat gaaaactatg cggtgaacta cttaaagttt tcaactgacc cttcctggaa
     6781 taaaagaaag gctttatatg tcaattggtt ctcaatgact gcatgggccg gtagcaatat
     6841 gatcggtaat tttttcggct cggtgattcg agtagatgct gaccttgtcc attttgcttt
     6901 gacggccatg ttcattttca tgtttatcat gcagatgaaa agcgcactac tgatctttac
     6961 aggtttattc tcaggcgtat taggggtcgt attcatggta ttattccaaa atactttcgg
     7021 attgattgca gcaacagtca ttgcttcatt tgccggattt atgctggaga aggcattcaa
     7081 aaaagaaaaa gctaagaaac taagagaccg cggtaaagat gtcaatgagc cgctcttcaa
     7141 cttcccggaa caggaggcca atcaccatga ctaaactata tttgctactt ttagttgctt
     7201 gtctgttcat cgtggcatat atcccgcgct tgttcccgat gctttatttt actcatcgaa
     7261 aagtgccatc ctggttcagt gactggatga aatatgtacc ggtggcatta tttgcggcgt
     7321 tagcttttaa agatgttttc attactcatg aacatctgga tattgcttgg aatatcaaaa
     7381 tagctgcaat gattctagta gcaggcgtgg cttacaaaac acgttcgatg gcgttgtcag
     7441 ttttgacagg acttgcgtct gtctttttgc tgtctatgct ttaaactgtt ttattttatt
     7501 aaaaacagag attgcgacat aagttgttca aactgatcta tccgaactgc atttgcaaca
     7561 gtcaattctg gatgcaagtt tattcgtagg gataaaaaag attagtgttg gcttatgatg
     7621 caagctcttt tttattttag gaattagaga gggatttgtc cttctatgat tttttgctat
     7681 aatagggaag atgtttattt tatgaaagaa tagttgaggg aatttaaatg aataaaaaat
     7741 tgatgcaagg aacattttgg ctaacctttg ctaatcttct atgtaaagtt ttaggggtag
     7801 tctatttgat tccctggcta agtatgatgg ggaacaatca agatggtatg cttgctacga
     7861 cattgtataa tgttggctat cttccttatg gattgttcct gatgcttggt acagtcggat
     7921 ttccaaatgc gattgcaaaa aaagtagctg tagccacaaa agaaggagat aacgctgctt
     7981 gtcggctgat ttttagaagt acgatcaata tcatgtttgt catcggtatc gcctctgctg
     8041 cactgatgta tttatttgct cctttactag ccggaatcag tccgattgct aacgttaata
     8101 atgggatact agctatcaga agtttatgcc catctttgat tgctatccca attcttagtg
     8161 caatgagagg atatttccaa ggaaaaaatg atctgcggcc ttatggaact tctttgatta
     8221 tcgaacaggc tgtgcgagtg atcgttatct tggctggtac ttattacttg cgcgtattga
     8281 ctgacggaac catattagaa gctgtattga tcagtacagt cgcttctttc ttcggtgggt
     8341 tagctgcgat tatccatatg tatatcgtcg gacgcagaaa agacttcttc gaacttaaag
     8401 attttttgat ttccagccgt tatttcgaaa gagaaaaccg atctgcctct gtctctatca
     8461 ttcgggaaac actaccgttt atttttgtcg gctcagtcat tactatcgtt caaatgatcg
     8521 accaagtaac gatgaaacca ctgcttcact ttttccgtcc agagatcgca gatcagcaac
     8581 tggaattctt attcagccgt gcttctgtca atccaaataa attgacattg atcctgatct
     8641 ccatggtagg aacagtagct ataagcagct tgccaatatt aagcacgatg aagaaaaaag
     8701 atcggataca aatcgaaaaa acagtaggag atagtttttc gattgcgtta ttgattcttc
     8761 ttccttcatt gactggaatg tctttattag ctggaccact atacacattg ttttttggct
     8821 atgatcctga aagtgtcgga tatttccaaa tggctttgct agcttctttg tttttctctt
     8881 tattcacgat cctatctacg atgcttcaat ctttgaatca ccatcgtttt gcgatccgat
     8941 taactgtaga agcaattatc ctgaaagtca tcttccaagt aatcggatta ggattagttg
     9001 gcggatacgg gatgagctta tcaaatggct tagcattcgg tattgtcttt gttcgcggct
     9061 atcactttat gtgcaaagaa taccgaatag cacctttagc aaagatcagc aattttttct
     9121 taaaaacttt ccgctccacc ctgattatgc ttgcagtatg ttttgccgtt ttctttttgc
     9181 tgaatcagcg attgtcaatg gaatcaaaaa gctatgcaat gatttattgt gtggctgtag
     9241 gaagtattgg cggcttagta tttttatttt ctcaattcgg aaaaaatggg tttcgaatgt
     9301 tgaaaaatgt taaacatcat agcagaagca aagaataggt taactaatcg ttttttgctg
     9361 tcacttgaaa aacggcaact cgtatgatta cgcttgtcgt ttttctattt tccaatttta
     9421 gtttcatatc taatcttact tatgatatag ttataaggtc tggaaaaatt ctttgaaacg
     9481 aggaaattaa acacatgaaa cttgcagtag ttacagatag ttcggcatat ctgccggaac
     9541 gtatcaagaa ccatcccgac ttattcgtta ttccaatccc tttgattatg gatgggaaaa
     9601 tttataacga aggaatcgat atcgaagcgg atgaatatta tggactttta aaaaacagta
     9661 aagattttcc tactacttca caacctgtcg taggggaagt tttgggttta tatgaggaat
     9721 tgaaagagaa agggtatgac acgattttaa gtatccatct ttcttcaggg atttctggct
     9781 ttgtcaacac attatttgcg atgaaagatg acatcagcgg agtaacggtc attccttatg
     9841 actctaagat cactagtatg ccgatgggac acatggtaga agctgcctta gacttaaatg
     9901 atgaaggtca gtcccttgat gaaatacttg cacatatcga tcgaatccga gataatacct
     9961 acgcttatct gattgtagat gatttgaaca atttagtacg aggaggacgt ttgacaaatg
    10021 gtgcagcgct gattggcagc ttattaaaaa tcaaaccgat cctgacattt tctgaaggga
    10081 aaattgtttt attcgaaaaa atccgttcaa gtaaaaaagc atttgctcga gctgaagaaa
    10141 ttattggtag aagaaataac gaaatacaac cgccagtcaa actttacgtg atacatgcaa
    10201 ataatttaga agtagcgatt gcggagaaag agaaattgca gaaaaaatat ccaaatgcag
    10261 aaatcgaaat tggtcatttc ggaccagtca ttggtacaca tttaggtgaa aaagccatcg
    10321 gcattgccat ttcagcgcaa taattccttt tattcaaaaa acataccaaa aatattccaa
    10381 catcatcttg gactttctac atgttactaa tgagcgtgta aaagaacgag atggtgtttt
    10441 tatttctatc aatgaagctc tttttctttg caatcctcac ttcaatcctc tataatgtcg
    10501 catatagttt agtaaatgag taaactacta atttacttat ttactaaaaa taaaaggatg
    10561 aggagttaaa ataatggaaa taccaacaaa tttaaaacat aaaccagtaa tcgttgtaga
    10621 agactatgat aaagttgatg gaagaaatgc attaaatacg gatgcaaaag ggctttcact
    10681 gggccttgct cagtggaatg atcgtggaaa agtcgatatc tcaggcaagg tatggcgaca
    10741 tactggagaa aaatggtcac gacagtcgga agaattacca atcacacgta ttttagattt
    10801 agcgatctta gctgcacaag gaagtttata cttccaagat gcttatcgtt atgaaaaatt
    10861 ttatgatcca gaaaatccag tcgtagacat cattggatta caagggaacc gaatgacggt
    10921 agaagtagat accaaaaatc caaagatcga tgaagacatc attttgtatt acgatacact
    10981 acaaaaagac ggagaactga ttggggaacg attccgtatt ttaaaacgtc ttttagatga
    11041 gctaggatat taatagacag agatgatcaa aaggggaaga gaagcatgga gaatttctca
    11101 ctaacagaaa accgaacctt ttcacggcta gaaaagcaaa tgatctggaa gaaaccgaaa
    11161 agccatcgga caagtgcaga agaatggcgg atcgcctccg aaatcaaagg gaattggcaa
    11221 gatcctgaaa tgaaaatcag taacgtactt ttggaaggag atgccgggtc ggggaagaca
    11281 caattagcca aagcactatc tgctgatctg caacttccct atacaaaagt gacctgtttt
    11341 gcagatatgg acaaatcaga tgttttcgga gccttattac ctgtagtaga ttctaataag
    11401 gaacaagacc aagaattact agaagctatt taccaaacag atacacttga agctgtactg
    11461 acactgatcc agaaccatta cggcattgat cctttttctg ctaaagaaaa attagcagag
    11521 ctagttcaaa ggatcgaagc tgattatcca gatgcaatcc attacagcta ttacccttct
    11581 gaaatcgttc gagcgattga aaaaggatat ttattagaga ttcaagagcc gactgtcatc
    11641 cgagatgcct ctgttcttgt ggcacttaac tcagcgctcg aaccaaatgg gatgttgaat
    11701 ttaccgacag gaatcattcg tcgccatcca gattgcgtca ttgtgatcac tacaaatcga
    11761 aattaccaag gaaatcgccc attaaatgaa tctttaagag atcggatgca acatgcggaa
    11821 aaaatggatc ttcctgcctt agaagtcatg gcagaacgtg cgatggcgaa aactatgatc
    11881 caaaaacaag aacttctctt aaagatggca gagattatcc gtttgttgga tgaaactgca
    11941 aaagctaacg ccatcaaagg tgtagcagga atgcgttctt atttttattg ggcaaatacc
    12001 tataagcaag gacaagattt actccagtcg atttatccaa aagttttgta taaattatcc
    12061 actgattcag atgaattggc aattcttgaa caagctttgt ctgacagtgg attgctactg
    12121 gaacttcagg acatattgag aaaagaaaaa tggggtcatc ctcaatctga gcatacaaaa
    12181 ggaagaacca ttagcgccga agaagcaaat gaacgaaaca tcactgaaaa tgctgaagaa
    12241 attctgcgct tagatgaaaa gaaatcgttg tctgctgaag aaccaaatga gggagaagag
    12301 aaacaagaag aaacaataga aaaaaacgag attcctcctc aaatgcaaaa agaacgcagt
    12361 agcgatatcg aaggaaaaaa tcaaaaagaa caacaaacag gagatgattc tcaagaaatg
    12421 tctgcttctg acatggaagc acatgataag gaaatcaaga agcaactgaa taaagaagcg
    12481 cgacaaatca tgaaggaaac gattcatgaa aaagaaggtc tcatcgttca ccgaccagct
    12541 ttccaaggaa aaacgccgga agcacgtgag ctacacatgc aagtaatgcc aatagtagaa
    12601 tcacttagcc ggcaaatttt agagttactg gataatgaac aaacagagac gtaccaaaaa
    12661 ggaaaatacg aaggtcagcg gttcaatgca agcaaagtag catatggtga tttgagaaat
    12721 tttgacaaaa agaacccgcc acatgagcaa ccttctttag cggtagctgt acggatcgat
    12781 gaatctgggt caatgatacg ggatgatcgg atcgaagcgg caaaaaaagc agcgattgcc
    12841 attgccgaat tttctaagaa agtcgatatc ccattgttga tttacggaga tacagcagac
    12901 cgttcgtcaa gagaaaagac ttctttgttt tcttataaag aatttgaaga cggatttcaa
    12961 tggttaaatg aaaaattagt cactatgaaa ccaaggcaaa acaatcgtga tggtgctgca
    13021 cttcgtttag cagcagaaaa attaaacaga caatccgcaa caaccaaact gttgcttaat
    13081 attagtgacg gtcagccaaa agcgttgccg gattatacag gcaaaaaagc aaaagaagat
    13141 atccagtctg ttttgaaaga atatgaacgt caaggaatcc tatttgtctc cgcagctatt
    13201 ggccaagaca aagaagaaat caagtcgatc tacggtgaaa gtcgttttgt agatattact
    13261 gacttgaatg aatttcccaa gcaaatgatt caactgattg cccgctatct atgataaaat
    13321 aaagctcaac gaacgcactt agcagattcg ttgagctttt cgtttctagt taccggtaac
    13381 aaggatactt ctaaaataga atcggttata atcaagaggg accgttaaag gagtgaaacg
    13441 atatgataca agaacaaaaa tggtggaaag aagcagtagg ctatcaaatc tatcctgcta
    13501 gtttcaaaga tagcaatggc gatggtcaag gagacatcaa tgggatccgt gaaaaactta
    13561 attatttgaa agatcttggt atcggcttta tctggatcaa tccgatctat caatctccat
    13621 ttgtcgataa tggttatgac gtaagtgact atcaagatat agaagagaga ttcggaacga
    13681 tggaagattt tgatttattg ctaaaagaag cacatgaatt agggatcaaa gtgattatgg
    13741 atcttgtcat caaccatagt tcggatcagc atcaatggtt tgaagaatcg aaaaaatcta
    13801 aagaaagccc gtatcgcgat tattacattt gggtcgacgg ggtagatggc aaagaaccga
    13861 ataattggac atcgattttc ggcggttctg cttgggagta ttctcatgaa actggacagt
    13921 attatctgca tgtttttgca aaagaacaac cagacttaaa ttgggaaagc gagaaattga
    13981 aagaagaact attcaatatg atccgatggt ggttggataa agggatagat ggatttcgtt
    14041 tagatgcgat ttctcatgta aaaaaagatg aatattcagt aaaagccaca gagaaccctt
    14101 tctcaccctt tcaaaatgtc tcaggaatcg aagaacattt gaccgatttg aaacatgttt
    14161 ttgaagagta cgatatcatg actgtcggag aagcaagtgg tgtcactgca gaagaaggac
    14221 cacaatgggt agggaaagac ggttatttcg atatgatatt cgaatttgat catatccata
    14281 tctggcagca agaaaaagaa gggcaattag atgtccttaa attgaaactt gcattaagcg
    14341 cttggcaaac ttcattggat ggtatcggat ggaacgcttt atatatggaa aaccatgatg
    14401 ttcctcgtgc cgtttcagtg tttggagata ctcgtcccga tttttgggct atgtctgcaa
    14461 aagcaatcgc tatgatgtat ttctttttgc aaggtacgcc atttatttat caaggacagg
    14521 aaatcggaat gacgaatatg ccctttgaat cgatcgatca agttgatgca gtagattcga
    14581 aaagacttta taaaaggctg cttgcggaag gtaagacaag agaagaagca ttggatatca
    14641 ttcgtgaaac aacgagagac aacagcagga cacccatgca atggacttcg gaacaatatg
    14701 ctggtttttc tacacatgaa ccttggctga tcactaatcc aaataccaaa acgatcaatg
    14761 tagaacaaca agaatatgaa ccagagtcgg tcctgcaatt ctataagaac atgatccgca
    14821 ttagacaaac caataaaggt ctgatatacg gttcttataa agaatatctt catgaacatc
    14881 cacaacttta tgtctatgaa agatatttag aagatgaaca atatcttatt atggtaaact
    14941 taacagaatc acttgctgac tatgaacttc caaaagaagc agatcagtcc tggacattac
    15001 tcttgtcaaa ttcctctagc ggagaatttg aagctaaagg catactagca ccttatgaag
    15061 ctcggttata taaaacaaac aagtaaaact tcctcgttaa agttcattag ttggactttg
    15121 cgaggaagtt tttcagattg ctctgtcaat tactcatttc aataattcgc tctaggacca
    15181 ccgatatatt taggacgaga gcgaagggct gtcacgtgag cttgtccaag ggttttcaaa
    15241 cgaggtctga caggtacttg gacatgtttg atatgcatac cgattgatgt gtcaccgata
    15301 tcgataccgg cttgtccaac tacgtgttcc acttcgacag gatcattgaa ctggtcaaaa
    15361 gcagcaacag aacaagcacc tccagcatgt agtgcaggaa caacagagac aatttcgaaa
    15421 ttttttgctt ctgccactgt tcgttctact actaatgctc ggttcaaatg ttcacaacct
    15481 tggacagcta gcgcaatttc tttaggatcc aacaactctt ttaacgtacg gatgatccat
    15541 tgaccaactt ccgcactgga attttttcca atatgtcctc caacgacttc gcttgtgctg
    15601 catcctaaaa caaaaagatc accttttttc aagtgtgcct cagccaatat gtcattaact
    15661 atttcagtca attggtcttt taattctttt tctgacaact tcattttcta aaaccttctt
    15721 tttcaattaa tattgcttcc gtgcttgaat acgttgaaga cttgcagtta taggaaaggc
    15781 aagtcccatt ccaatcagat tttggaagat gtttcctggt atagaagcca ctccagccgg
    15841 ccaatcatat aaaatccaac cggcgatacc atagccgatg atcataacta agcttcctaa
    15901 taaaagccct aatccccaca tacgagtaga agatttgctg aaagaaccag caacatatcc
    15961 ttgtaacccg tggatcacta atgaaaaaac tgcccactgc ggatatcctg aaatcaaatc
    16021 gatcaataga ccactggaag caccaacaac taatccaccc gttggaccat aaagaaaagc
    16081 agcggtatag atcccggcct cgcataatgt cacaaatcca ttcgtagccg gtacagggat
    16141 caaaattgtt aatgaaaggg caactgtcaa cgcaatcagc atagcataga tcgttaattg
    16201 cttagttttc atttctcatt cctccttttt gaataccgcc agaccagaca cttccggtat
    16261 gatcgttcat cagcacgcca ttagaaatac aatgggcaac aaatttttta ctttctgcta
    16321 ctgctttggt aaaatctgcc cctaacacaa gattcgctgt tattgcagaa gaaaaggcac
    16381 aaccggcccc gtttactgtt gtagtgtcga tttttttatg agaaaatacc tcataatgat
    16441 caattgaata gagaagatcc acagcttcat ctccagccat ccttgtgccg cctttgatca
    16501 caatgttttt tgttcctgaa gcagtgagtt ctttagcgag atggatcatt tctgttaacg
    16561 aagagggaag agcttgacca gaaagtaaag cagcttctgc caaattaggc gtaatcatcg
    16621 taacaagtgg aaaaagttct tcgatgagct gcgaaatata caattgattg atcacagctt
    16681 cagtttcttt gaatgccaaa acagggtcta aaatgattgg gatattttgt tttgttttta
    16741 tgaagtctcg aacaaccatg attgcttcac ttgaattcaa taacccaatt ttgataccat
    16801 ctaatgaagt cattttatca atcgaaacta actgtcgttt aagcaattcc aaagatatag
    16861 attccagcat aaatcgctca ttaatatcta gtgcccctat agaagtcaag gcgcttagtc
    16921 cgaatagacc aaaattctca aaagttttta aatctgtttg gattcctcca ccagcaaatg
    16981 gatcagaacc gccaattgtc aagattcttt tcataacatt ttcctccatg aataagagta
    17041 taacgaaatt ttcaaaaaag aaaaacagcc aattggcata tttttatctc atccaattta
    17101 aaaaaacaaa aagaaaagaa agaccaaaat ggatctttct ttccttaaat agttaggact
    17161 tttgtgattt taattctttc tcgatttgaa gccgttgcac tttcattgta gctgttcgcg
    17221 ggattgcatc aaaatcacgg atgataggga cgttcaagcg aggaagttca tggacttgct
    17281 cccaccatcg attccaatcc atttctttat caggagctaa agcaataatc ggttgtggag
    17341 aatgattttt atcccttaca atcactactt ctgccaaaaa atctaacgaa tctaataaaa
    17401 agtcttcaat agctaatgta ctattgatcg tttcgatcaa atccacttgc cgatctttca
    17461 aaaataggtg gccatgctta tccataaaac cgtaatctcc gctatcccac caatcgccat
    17521 aaacattttc ctggaaccgt gcatcttcct tgtaataagt caaagcccgt cctttagaca
    17581 gtaattgtat atgaccatct gtgttttcag gtaggacatt cccaactgaa tctgtaatcc
    17641 gagcgcttgt catgtcttcc agtccaacgc ccatatctct tgcatcactt gttttcaaac
    17701 tctctagtgt atgagcctta agaatcattg gtccgcattc actttggcca tatacttgaa
    17761 gaaataccgc atcctgtgcc atcgacgttc gcaaaaatgt cttcattgtc tggttgttta
    17821 tagcatcaaa agtggagtga tagtatcgga tacccgaaaa agcttctgga tgctccttag
    17881 cagtaaaacg ccactgaaca aagttattcg gatgggtctc tagtgcaatt ggccggtgag
    17941 cttccaacat atgaacaact tttgaacttt gtgcgtttgc taaaggcatc ataggaaatc
    18001 ccatggacat caaagaagag ataccaatat tgaatctgga atgcactgga gagatgtgaa
    18061 aagcgattaa tttcttttcc gaaatttttg tgaaaactgt tttttgccat ttcgtccgcc
    18121 atcccataga atgagcagaa tgacaaataa gtttagggat accagttgta ccagaagtat
    18181 gggtcatata agaaatttca tttttgtcta aaaatgattg agaaacagac aaagcaggtt
    18241 gttccattaa ataaagaata gg
//
LOCUS       DAFLWQ010000057        18197 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.058, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000057 DAFLWQ010000000
VERSION     DAFLWQ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18197
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.058"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(16..840)
                     /locus_tag="L1V16_001928"
     CDS             complement(16..840)
                     /locus_tag="L1V16_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBN1276267.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(813..1493)
                     /locus_tag="L1V16_001929"
     CDS             complement(813..1493)
                     /locus_tag="L1V16_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBN1276268.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(1516..2454)
                     /locus_tag="L1V16_001930"
     CDS             complement(1516..2454)
                     /locus_tag="L1V16_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBN1276269.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(2699..3562)
                     /locus_tag="L1V16_001931"
     CDS             complement(2699..3562)
                     /locus_tag="L1V16_001931"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBN1276270.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(3704..6277)
                     /gene="mprF"
                     /locus_tag="L1V16_001932"
     CDS             complement(3704..6277)
                     /gene="mprF"
                     /locus_tag="L1V16_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBN1276271.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            6418..7224
                     /gene="proC"
                     /locus_tag="L1V16_001933"
     CDS             6418..7224
                     /gene="proC"
                     /locus_tag="L1V16_001933"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBN1276272.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(7303..8859)
                     /gene="rny"
                     /locus_tag="L1V16_001934"
     CDS             complement(7303..8859)
                     /gene="rny"
                     /locus_tag="L1V16_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBN1276273.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(9270..10319)
                     /gene="recA"
                     /locus_tag="L1V16_001935"
     CDS             complement(9270..10319)
                     /gene="recA"
                     /locus_tag="L1V16_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBN1276274.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(10428..11669)
                     /locus_tag="L1V16_001936"
     CDS             complement(10428..11669)
                     /locus_tag="L1V16_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBN1276275.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(11909..12487)
                     /gene="pgsA"
                     /locus_tag="L1V16_001937"
     CDS             complement(11909..12487)
                     /gene="pgsA"
                     /locus_tag="L1V16_001937"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBN1276276.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(12696..13619)
                     /locus_tag="L1V16_001938"
     CDS             complement(12696..13619)
                     /locus_tag="L1V16_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1276277.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(14357..15643)
                     /locus_tag="L1V16_001939"
     CDS             complement(14357..15643)
                     /locus_tag="L1V16_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBN1276278.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(15636..16904)
                     /locus_tag="L1V16_001940"
     CDS             complement(15636..16904)
                     /locus_tag="L1V16_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBN1276279.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            17156..17617
                     /gene="mscL"
                     /locus_tag="L1V16_001941"
     CDS             17156..17617
                     /gene="mscL"
                     /locus_tag="L1V16_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBN1276280.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(17676..18122)
                     /locus_tag="L1V16_001942"
     CDS             complement(17676..18122)
                     /locus_tag="L1V16_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1276281.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
BASE COUNT         5190 a         3981 c         3181 g         5845 t
ORIGIN      
        1 tcttttcttt ataatttagt tattttttct tctgaaggca accaatattc gtttgatgat
       61 atttacaatc aggaacaaag caataaagac taatgtgatt gttgctcctg gaggtgtatc
      121 tagataaaac gagctagtta gtcctgacag catccctaga aatcctacac aaacactgat
      181 agcaatcacg acattgaagc ttttgcctaa tcgcataccg attgctgcgg gaagaaccat
      241 gattgcggat atcaaaagtg caccggcaat cgggatcatc acagcaatag ccacaccagt
      301 aatcacattg aacatcatcg acatcaaatg aacgggtagc ccatccacgt gggcggtatc
      361 ttcatcaaaa gtcagaacat acatcggccg tttgaataaa aagaacaata taccgatggc
      421 aacgaataag attcctaaaa agatgacttg ctcccatgta atggtcacga tcgaaccaaa
      481 cagataggat tggatacttg ttgctgaatt ccctccgctc aaattcatca atactaacgc
      541 tagcgccaaa ccaccagcca ttaaaatggc aatggagatt tctgaatagg ttcggtagat
      601 cgttcgcaga tactccaata tcacagctgc taatacaacg actagcatgg tcgtaagtgt
      661 aggattaagg ttcaaaaaga atcctaacgc tacccctgct aaagagacat gagaaagcgt
      721 atcagccatc agcgattgtc ttctgatcac taaaaacaca cctagcatcg gggcgattcc
      781 ggcaatgaag atagcggcaa gaaacgctct tctcatgaat tcatatgaaa gcaacgccat
      841 tgagaatcct cctttctcac cagtcggatc tgtctgtccg catactgttt gatatcttca
      901 tgatcatggg tgatcattag aactgatttc ccatggacat gcgcactatg tcggagaaga
      961 cgataaaatt catttctgga ttcttcatcc atacctgttg ttggttcatc aagaacaaat
     1021 aagtcagggt cagtagcaaa aatacgcgct aaactgattc gctgcttttg tccgccagac
     1081 aattcaccta ttcgccgatt tcgcatatcc cacatcccta cagcttctaa agcacgctgt
     1141 acatgttgat gatctttttc agagagacgc ttgaaccagc ggcctcttgg atatcttcct
     1201 gaacggacta attcgatcac cgtactagga aaacctgcat tgaaagatgc aacttgttga
     1261 ggaatataac cgatacttaa tttttttcct tcttgatttt tctcagcaat ctttatcatt
     1321 ccttttgaag gtttcagtaa tcctaacgat gctttcacca aggttgactt ggctgctcca
     1381 ttttctccag ttaaaatgac aaattcaccc gcatctacat gataagagac atcttctagt
     1441 acaggttcat catcatagta aaaggtcaaa tcagatattt cgatataacg caccttacaa
     1501 cctccattct aaaacttaat tgatactttc ttttaaagct ttcagatttt tttccatgac
     1561 agaaatataa ttttcgcctg ctttgatttg ttcattagtc aagctttcta aaggattcaa
     1621 cacttctagc ttcactcctg tttcattcga caatgtctca gctaccttcg aagaggcatt
     1681 ttcttcaaaa taaatcactt tgatgttgtt tttcttcaca aattctttta gctcagctaa
     1741 gcgacttggt gtgggttcct gatctggtga aacgcccgaa atcgctactt gttttaagtc
     1801 gtattgattc gctaaataag caaaagcagc atgctgagtg acaaatgtgc ggtttgttgc
     1861 atcttttagc tcatcggagt atttttgatc cagtgcttca agctttttga tataagcatc
     1921 ggcattcttc gtaaaagttt cctttttatc tggatatttt tcgcctaatt cttcagcaat
     1981 cgttctgact tcttttatag ctaataccgg atcgagccaa acatgtggat cgtattcatg
     2041 tgaatgacca tgcccttctt ctgattcttc atgttcgtct gcttcttgcg attctaaacg
     2101 gtcgattcct ttagctgctt cgatcatcaa ggtctgtttg ctatccactg aatcctttaa
     2161 cgaatccaca aaaaattcca tgtctgaact attatacacg aaaacatctg catcggaaat
     2221 ttctgctctt tcttttgcac ttggttcgaa atcatgcggc tccgttccag cagggatcaa
     2281 aagtttcacg tttccttcat cccctacgat ctcttttgta aaatcataca tcggataaaa
     2341 agtcgtaacg atcgtcaaat cctctttttt gtctgcttcc ttgttcgtat ttccacatgc
     2401 tgcaaacagt aaagcaccta tcattaccgt agctgtcaaa agatattttt tcatttatat
     2461 gctcctttca atgaacaaat cggaatttta cgatttatta acgtgaacta atgtatcaaa
     2521 ataaaaaaac acagtcaata gaaatccatc aatttctgat ttaagcatgt atattcttga
     2581 ttaaatcgta aaatggatga gttgctgctc atatctagcc atttcactac aataaaaaac
     2641 tgaagaatac cattttagga ttcctcagtt tttcatcacc tattttactt cttatatttt
     2701 attgcagggt tcgtactaaa taaacttcct cacaaaaacc ttttaaccca ttatatactc
     2761 tctgcgctct tgaataatgt tgacacaagg caaaaacggt tggtccgctt ccactcatca
     2821 atgcagcatc tgctccgtac ttgatcatac gctctttgat ttgatggatg actggatgcc
     2881 gctttcccgt tatatcttct aaactgtttc ccattttttt gatcatctgc tgataatctt
     2941 gctctcggat ggcttcagca agtccgtgga tgtcttgatg ttggatggct tgcgtatcta
     3001 cttctctaaa cactgtacgt gtagagacac tcattcttgg tttgaccaac acaacccagc
     3061 actgtggcat agaaggtaat acttggattt cttccccttt gccaccgaca aatgccgtac
     3121 ttccgtagac acagtaagga acatctgtac cgacttccaa accgatttct gccagttctt
     3181 ctaacgaaca gcccagattc cataattggt tgatccctct tagagcagct gcacagtctg
     3241 tacttcctcc gcctaatcca gctgctactg gaatattctt cttaacaaag atcttgacac
     3301 cggttttgat attgtattta ttttttagca ataaagcagc ttgataaaca ttgttccgtt
     3361 catctaccgg taaaaatgct ttatttgttt ctacaatgat tttgtcttct gttatttctt
     3421 caaaaaatag atgatctgcc aagtctacgc tcgacatcac catttccaac tcatgatacc
     3481 catcttgccg tctatataat acatccagtc ctaaatttat cttggctggc gctttttcaa
     3541 tcaattccat cctctcaccc attcgaaaag tctaagtcgc aagtattcta tcatagggaa
     3601 aaataaaagt atagcttatg tctgcctagt ggttgatttt gtcatcgttt caacagcttt
     3661 cacagaattt tctcttcata atccaaacaa gttctagtga ttcttataat tctgtgagca
     3721 cttcttctgc caaactcgga acatttcctt tttcttttcc tatcagactg agtagctgca
     3781 tggtagcaaa tccgaaatta cttcctttcc tataagcaaa ataacgtcct tcccaatgat
     3841 cgacatattt taatttcttt tcataagcag actggaagga atagaaaaaa ttaccataat
     3901 tatatacgat atgcatgact ttttcttgaa agaaagaaaa atctgtttct ccaacattag
     3961 ctaatggagc taagcctaga ttggcttccg agtagcccat tttctcgtat acaataaaca
     4021 gattggctaa cagatagtca gctaattcct cagattcttt aggtaagacc cgcaacaaat
     4081 catatcccgc ctgcttcttc gtcatcggct gagcggtgat gaagccaacg actttttgat
     4141 ctttacggac aataccgaca ccgctagata atacatatga tttatcaaat cgtcccacag
     4201 agaagtattt ttctcgtgca ccttgaagcc atttttgtga aacttcattt acagcttgat
     4261 gtaattcttc cggcagttga tcgtaccaag taaaatggta tccttctttc atcaaacgtt
     4321 gatattcaag ttgctgactc agccgagaca agtcttctgt tgctagatca acaatccctg
     4381 cttcacctac tttcgtgaag tgaaaaccca attcatgaag catcactacg tagctttctg
     4441 atatcttata aaacgcaagc tgatagccta aacaatctgc ttgtttcata aactgattcg
     4501 ttgctgcccg catcatttta ggattgccaa ctggatctcc taaaacaaag catttgtttc
     4561 ctttgatctg ataaccaaaa acgacttgat cttggtcgtc ttcttggtaa taaaaataac
     4621 tgtaacctga caagcgaagc tgatggcttg tagctgtgcc tccgtatgtt tccaataaac
     4681 ggtcaaaacg gtctttttcg tactcactgc caagcttcgt agtatcttca gctaaatatt
     4741 gataaagcgc cactaaagct agcaatgaga tgcccaaacc aataagccct gagaaccaca
     4801 catcatctga aggaaacaaa ataaaatgat ttcctgttat tcgaccgact aaaaagcgtc
     4861 cgctgtgata gcctgcaatt gcgtaaacga taaacaaaaa gccgaacaag ctagcatcaa
     4921 agattatagc tccccaagaa taaacgaatt ttgttcgata aaattctttt ctggataacc
     4981 acacagctaa cagaatcaag acatatacca atatcaactg ccaagataac gtacgtgtga
     5041 ttgtatttaa aataccaaaa gatagtaaag caatcgtagg cagaaatgcc tttttgactt
     5101 ttactgaaag tgctctagca aggccgagta ataaaaagcc aaccaataga ttcactgtct
     5161 gatctaaaaa attgaatgag aacggcaata atacttgaaa tagccgactg attgcagaca
     5221 gattagtgat tgttgataga agtaccatca tgatccccgc aaaatagaca gcacttacga
     5281 gcacgatatg cgcaaccttt tggaaaaaca gtcgcggaat gttatctaaa aatcgattga
     5341 ttttgactcc tgtatgtgtg atgaacaata gaagtcccgt cataaaaggt agaacataat
     5401 aaaacaaccg ataatataat agccaaacta ctgctacatc ttgccgaaca ggcaattgac
     5461 tcattcctaa gatcatcaaa acgtcaaaag tccccattcc acctgggacc atcgtcagca
     5521 ttcctatcaa tgtagcaatc atgaacatag gatagatcga aagcatcgaa atatctattc
     5581 tcatcaactt gccgatgatc aaaaataccg caagggctcc cgtccattgt ccaaaggatg
     5641 ccagtagcag accaagcaag ccttttggat aaaactcgaa gaacaatgtc tttctcttta
     5701 gataagcaaa aaagaaaatg actggtgcta aaaaactacc gccgaaaagc cagatccaat
     5761 agcttcgaaa aatactttct gactgaataa aaaagacatc aataaatgta agaaacgacc
     5821 atacagacaa accagtcagc ataaatagtg cgacttttga tacagtggct aaaaccattt
     5881 ttctatttgt ctgctttcca taaaaactag cccgcagact tgctcctacc acaccaccaa
     5941 aaccggcgag attgttgatc gtgtttgtta cccacgcagc aagaagaaac tcttttcttt
     6001 ccatttttgg ttttccttgt ttttctaaga ctctgatcgt cacccaatca tacaacaaca
     6061 tcggagtgac acccagcagt ccagccagaa tcatgagcag gatcgtcatg cggctttgtt
     6121 gtcccatcct ttgccaaata tcttgccaac tcatgccatt agcaatattt gcgacttgat
     6181 ttgccacaaa gactaacacg gagccgaaaa aaatcagttt taaaatcaga ctatgttcct
     6241 ttatccattg cagcatcaag tatcgtttat ttttcacatt ttcccattcc taacttgtat
     6301 acttttgtgt cataccccaa tgttatctta tttattttaa tttttccact ttagacctgt
     6361 tctttgcttg cgatgataga aaaagaaaga tatcctaatg ctaaaggaga ggataacatg
     6421 aaagtaggat ttatcggcac agggaatatg gcacaagcta ttattgatgg tttattaaaa
     6481 aaaggaacag tctcgaaaga agaggtgttc gtttccagtg gacattttga aaatgcacaa
     6541 aaatttgctg ctgaaactgg cgtccatgca tgcaaaagta atcaggaagt tgcatcacaa
     6601 tcagatatcg ttcttttagc cgtgaaacca aaaatcattg aaaaagtatt ggaagaacta
     6661 agagaatata gccagaaagt cttattcatt tctattgctt caggaaaatc attaacagat
     6721 ttagaaacag cgcttgaaga tcctcaggcc tccatcgtac gtgtgatgcc gaatgtcaat
     6781 gtcagcgtag gagcaggcgt ttctgcgatt tgcaaaaatg aagctgccac ggaggaacag
     6841 cttcagcaag ctacgatgat ttttgaagca atcggcagcg tctatccttt agcagaatca
     6901 gatttcagta cattcattgg ccttgctggc agctcacccg cattcgttta catgctgatc
     6961 gatgcgatgg gacggactgg tgtactgaat ggtttgtcca aacagacagc cactgagatt
     7021 gctgcaaaag caattatggg ttcttgtcaa aaattccttt caagtgataa aaatccatgg
     7081 gaacttgtag accaagtttc ttctcctggc ggtacaactg ttgcaggtgt agttgcctta
     7141 gaagaagcag gattcatccc agcaatcatc aaaggaatca atacgacgat cgagaaagat
     7201 cttgagatgt tgaataaaaa ataatgatag caatgttttt tcgtgcctta caaaaaaaga
     7261 agagctgtgg cttttgccgc ggctcttctt ttgtattttt tattatttag cataatcagt
     7321 tgcacgagtt tcccgaataa cgattacttt gatgtgtcca ggataatcca gttcttcttc
     7381 gattcgttta cgaatatcac gtactaaacg aacagcgtct aaatccgaga tttcttctgg
     7441 cttgaccatt acccgaactt cgcgtccagc ttgaactgcg taacttgatt ctacaccggc
     7501 gaagctgttc gaaatatttt ccagacttct taaacgacgg atgtagtttt ctaatgattc
     7561 acttcgcgca ccaggtcttg ctgctgagag cgcatctgct gcagctacaa ggacagagat
     7621 aacagaagta gcttccacat ctccatgatg agaagcgatc gcgttgatta ctactgggtt
     7681 ttctttgtac ttggcagcta attccgcacc gatctcaacg tgagatcctt caatctcatg
     7741 gtcaagtgct ttcccaatat catggagcaa cccggcacgt tttgctaatt ggatatcttc
     7801 gccaagctct gctgctaaga taccagctaa ttttgcaacc tcgaccgaat gcttcaagac
     7861 gttttgtcca taactagttc tgaatcgcag acgtccgatg atcttgatta gatctggatg
     7921 aagtgtatga gcaccgactt caaacgctgc ctcttccccg tattcgcgaa tacgttcatc
     7981 catttcttta cgagatttct cgaccatttc ttcgatacgc gctggatgga ttcgtccatc
     8041 ttgtatcagt ttttccaagg tcatccgtgc gatttctctt cggattggat cgaatccgga
     8101 aagaacaact gcttccggtg tatcatcgat gattaaatcg ataccagtca gcgtctcaag
     8161 cgttcgaata ttacgacctt ctcgtccaat gatacgacct ttcatttcat cattcggaag
     8221 ggtaacgact gaaacagtcg tttctgaaac ttgatctgct gcgcagcgtt gaatcgctaa
     8281 tgataataag tttttcgctt tgcgatctgc ttcttctttg gcacgctgtt cagattcttt
     8341 taccattaga gttaactcat gattcagctc ttcttcagtc gatttcatga tgacatctcg
     8401 tgcgtcctct tttgataaac cagcaatttt ttctagttct ttttgttgat cttcaatcat
     8461 tttttcaacg tctttttctc gctcttcaat taattgctgt tttgaactaa gtgcttcttc
     8521 tttactttca agtgagttct cgcgtttttc taacgagtca tctttacgat tcagcgtttg
     8581 ttcgcgttga atcaaacgat tctcttgaga ttttaattct aacttacttt ctctcagctc
     8641 actttcaact tcagaacggt atttctgatt ttcttcctta gcttctaaca atgcttcttt
     8701 ttttagagtt tctgcttctt tttttgcact atcgatgatt ccagcagctg atgattgtgc
     8761 accagctatt tctttctcgt gacgtgactt tgcgaccata aaccctaaac caagaccgac
     8821 aattaaaccg atgatagcga ggagaatgtt gaataccata aaatccacct ccatactatc
     8881 tttttcattt ttatcatcta tacagcttct atgataaatt attctaaact cgtcaatatg
     8941 catcttcgca tatatgtgta caaaaaacat gcacaacttt attctaatgt ttgtaccccg
     9001 tagtgtcaac tttaaataaa caaagaaacg gctttctact tattcattaa acgatggttt
     9061 ttaaaataaa tgacactagt ttcatatagg taaaccttta aattgagaaa cttttctatt
     9121 aaattattct ttgtagatga acagatattt ttattttatg tacccactcg tataattaaa
     9181 taactcacga tttctttatt caataaaaaa acggcaggtc aaggagagta cctactcttc
     9241 agaccagccg tttttgttta tcataatttt tattcttcta ctaaaggcaa ttcttcttgt
     9301 cctttttcat cttctgggac agcgacttct tcaccaatac cataagctgc tctaactaga
     9361 gcagaaactt ctgccatcat ttcaggatga ttagccatat agattttagc gttttcccgt
     9421 ccttgaccaa tccgatcttc tttataagaa taccaagcac cgcttttatc aacaatgtct
     9481 ttttctactg ccatgtctag aagttctcct tcttgtgaga tccctaaacc atacatgaca
     9541 tctacttcag cgattttgaa aggaggtgct actttgtttt ttacgacttt gatctttgta
     9601 cggttaccaa caatatctgt accttgtttc aattgttctg cacgacgtac ttccaaacgg
     9661 atcgttgcgt agaatttcaa tgcgcgtcct ccaggagtga tttctggatt cccaaacatc
     9721 acgcctactt tttcacggat ttggttgatg aaaatagcga ttgtttttgt tttgttgatc
     9781 gaaccagaga gtttacgcaa tgcttgagac atcaaacgtg cttgtaaccc gacatgtgag
     9841 tcacccattt cgccgtcgat ttctgctcgt ggaactaaag cagcaactga atcgactact
     9901 acgatatcta cagccccact tgatactaaa gcatcagcga tctctagacc ttgttctcct
     9961 gtgtcaggct gtgaaagaag tagttcatcg atattcacac ctaatttttg tgcatattgc
    10021 ggatctaacg catgctcagc atcaatgaaa gcggccgttc cgccattttt ttgtacttct
    10081 gcaatagcgt gtagtgcaac tgttgtttta cctgaacttt caggtccata tacttcgatg
    10141 atacgtccac gggggtaacc gccgacacct aaagcgacat ctaacgcaag agagccactt
    10201 ggaattgtag agatttgttg gtcgattttt tcgcccaatt tcataataga gcctttacca
    10261 tagctctttt caattttttt cagtgcagca tctaaggctg ctttacgatc atctgccaat
    10321 acgataatcc tccttatatt tacaaatcag agcaacattt cattatcctt atcatatctt
    10381 ttttagtgaa aaaaagcaag aaaaaaccga acaaatattc gcatttatca ttttcttaaa
    10441 agctgttttc tcaaaagatc aaatccttgc ataaccgcat tatatctgat agcagcacga
    10501 tctctggcaa agtgatattt ttccgaaacc acgccgtctt tagatgaaat agcgatccat
    10561 actgttcctg cagattgacc ttctaacgtg tccggtccag ccactccggt gaaagctaca
    10621 ctgtaatctg ttcttgctat ctcacgtgct tgaatggcca tctgctccac acattctttg
    10681 ctgactgttc catattctgc taatagctcc ggatcaatct ccagaaaacc agcttttgtt
    10741 tggagcgagt aggtaacgaa tccgcctgga aatacttcag atacaccagc aatgtcgcct
    10801 aatgcggctt ggaaggcgcc ggctgtcaaa ctttccgctg ctgttacagt ctgcttgttt
    10861 tctttcagta gttccactac gacttttgct agcgaattat catcgccgta tccataaaaa
    10921 tattccccta ctcgttcttg gattttttct tctaatgcta aaagagcttg attccctgcc
    10981 tgaacatcat ttgttttcac tgtcagtcgt aatgtcactt catttggttt ggcatatggt
    11041 gcgatcgttg gattgatctg tgtctcaatc agatctttta gctcagtgac cagtcgcgat
    11101 tcaccaatcc cataaaagcg caaaacttta gaaattagtt tttcttcaga aggaaaacgt
    11161 tcctctagta aaggacgtac ttgttccaca aacattggtt tcaactcatt aggcggaccg
    11221 ggaagaagga tatacgcatg tgtatctgtt tgataaaaag tccctaaagc aagccctgta
    11281 cgatttggta gaggaacccc gccttcgata atctgggact gttgcagatt gtttttggtc
    11341 atttttcgat gggttgtttc aaaatatgcc aataattttt tgtatccttc cgtattttgt
    11401 atgagagact taccgaggtg agccgcagtt gcttcttttg tcaggtcatc ttctgtcggt
    11461 cctaatccgc cacataagag tatgagttca cttcttgttt cagctagagc aatcaactct
    11521 tctaaacgct gctgattatc tcctacaact gtttgataat aaacttcgat acctagatca
    11581 gctagctgtt ctgacaagaa agtggcattc gtattcacga cttgtcctag taaaagttct
    11641 gttccgacag ctattatttc tgctttcatt acttcccgct cccttatata gtatacgctg
    11701 tatttttata tttttttatt taaaaagagg gcaaggagct gtgacaaaaa tcttgtcaca
    11761 gctccttgtt ccaaataaac agtgttctcc tgccaaaacc tcggtcataa gtcacaatat
    11821 acataaaaca tgaaaagctg ttttttgaaa ttatcccttg tgactcagag ttagacggca
    11881 ggctcacaac ctctccacta aacgatactt acattgatcc tttgaacaca ccgctgtttt
    11941 tgatgaagta atccacacct gaatagatag taaagatcag acaagcataa agcatgattt
    12001 gatctactgg aataccgatc aggctgaatg ggatattatt gataaacagc aagataatag
    12061 caaccatttg tgtagccgtc ttgacttttc ccggccaagc tgcagccatg acttctccat
    12121 gttcgacaag tagtaaacgc aagcctgtga cggctaattc acgacagaca atgatcgcta
    12181 ctacccaacc aggggccttt ccttggtcaa ccaacatgat aaaagcagtc ataactagca
    12241 ttttatctgc caacgggtcc gcaaacttgc caaaattagt gacaaggcct cgcgcacggg
    12301 caatttttcc atctaaccag tctgtgatac tagctaaagc aaaaataact gcacctacta
    12361 gctgtgtgac agccagtgtg gtgtctccta cgttaaattg tccccaatct aaaggtaaac
    12421 ctacaaccaa aatgaaaatc gggatcatac aaattctaag tacagttaat ttatttggta
    12481 aattcacact atcgactcct ttcttcccta ttctacgtga ctatcagcga agtttccacc
    12541 gatattattt acttttccaa atgaatttat tcaaaggagt atttttattg aaattgatct
    12601 ttttgaatta acgaagaagg accgcgacac agatttgtca cgatccttct tttttatacc
    12661 tacaagtaaa cagatgcgta aactaattta tacgatcatt ctgcgtattg aagagtaagg
    12721 ttcacatttt ttggactctg attgttttcc cctggattaa ctggtacgga ttctccattc
    12781 gctttgatcg ttgcattgct tgctgcacca atcgtgatgg tcgcatttgt tgctgtttcc
    12841 ggtaacacgg tactctgtgt ttcatttgct gccagtgtcc cttgataaac ataggcattg
    12901 tctactagca cacctaacca tacacgattg acagcagtaa attcaagggt tacaggcttg
    12961 gtagcgtctg tgatatttac tgcgatggca ctgccagaat cttctcctgt agctattgcc
    13021 attttctttt cttcacttga ttttgttgtt gattctactg tagaagactc tttggtctgc
    13081 gtgctttgct ctgaggaaga ggactcctcg actgatcctt ctactttaag cgaagaagct
    13141 gtgtctccga ttattggatc agcttgacga tcttgccaag tcatatagcc cacgacaacg
    13201 acaatcgcca aagcaaccaa tcctaataaa atgacaggaa gacttgtcca aaagcgactt
    13261 ggatgcgatt cttcctgatg cattgctttt ctagaagtac ttactgtttc aggctgcgga
    13321 cgttcaggga ccgatcctgt caatttgctt ttcccatcaa aaacatcgac taaatggtct
    13381 ccatcttctc ctacagcttc agcgtattgc cgaataaatg cccgcacgta aaatttacca
    13441 ggcaattggt caaaatcatc attgtcgatt gcttccaaat aacgtttttg aatttttgta
    13501 atctgctgta attcatctaa agatattttt ttattcaggc gtgcttgccg taatttttct
    13561 ccgatggttt caaaagccac tcgttcatct tctccagtct gtttgattct ccgaagcatc
    13621 tgctgttgca acgaaagacg ttatgtttgg gtgctgtgac aaaagtcatg tcacagctcc
    13681 ttttttccga ataaacattg ttctcctgcc aactcctcgg tcacaagtca caatatccaa
    13741 taaatataag aagctgtttt ttgaacttgt tccttgtgac tcggagttaa acggcaggct
    13801 cacgacctct ttcttaaacg gtgttcaatc agctgttcct cggtattagc tcaaaaaccg
    13861 gcaaaatata aggagatatt tttccgtatg tttctctaat actcaggtca aaacgctgat
    13921 ttcacaacct cttccttaaa cggtgttcaa aagcttgcat ctgcggtaat aagtccaacc
    13981 aagttaaaaa cattaagaag ctgtttttac ttggctgttc ttattacttg atgcagggca
    14041 gctttttcac aacctcttgg tacacggtgt tccagaagta gcttcttcgg caataagccg
    14101 aaatatcaca aaaatttgag aagcaatttt cgtaaattcc ttcttatttc ttgaagctga
    14161 ccacttctgt cacaacctct ttgattactt cgtttgattt tattttaata taagttgatt
    14221 aaaagagagc atgatttgtt ttattttctc actaattttt ccaacacaac taagaatacc
    14281 ataaaagctg attttggagg aggttcctac tacaagtcta aaacgaaatt taagactttt
    14341 cctcataaat actggtttat tttggtctca tgtaaaactc gctgaaggcc tcttcactta
    14401 taaatgcttc cccagctgcc agtacgtctt tcatttggat cgaatcgatg atttcaggaa
    14461 gatcaaataa agttcgatcg ccaaataaac tttgcgtaaa ttgattggca atatattcga
    14521 tcgaatttaa tgattggaaa tattgtccaa gcattttctt cttcagcaaa tcgagatttg
    14581 tttctgacac ttccggatca tcagcgaatc caagaatgat ttctttgact ttttctgctg
    14641 ctttctctgg ttcgtccgta tctccgctga agtccgcaaa gtgaaattca cgatccaagc
    14701 tgaattcaaa accaaagctg tcatcgataa ttccttgatt gtacatcgct agatagtttc
    14761 gagaagtatt gcctaaaatc atttggaaca acagattgat tgctgtttta tagcgtaaca
    14821 gttctgttcc ttcttgcggc aatgtgtcta atcctttaat accaagtaca aatttatctc
    14881 gtgtaatggc tgcttccaat gcactttgtt tgatgatttc ttttgtgttt tcagggaaat
    14941 aacgtacaat ttcttgcttt ggagggaaat tttttgcttc ttggttttcc cgaataagtt
    15001 tcatcaattt ctcaggctcc atcttaccaa ctacaaataa aaccatattg cttggctgat
    15061 aaaacgtccg atagcacgta tacaagtctt gagctgtgat tttgtcgata ctttcaaccg
    15121 tgcccgcaat atcgatatgc aatgggtgtg taggatacaa gttatttagt atgccaaaaa
    15181 acatccgcca gttagggtcg tcttcataca tttggatttc ctgaccgatg attccttttt
    15241 ccttgtttac agtttcttct gtgaagtaag gtgcttgtac aaaatcgatc agagtcgtca
    15301 gattcttttc tacctgatcc gtcgtagaaa acagatagct ggttttcgta aaacttgtga
    15361 aagcattggc ggaagctcct tgtttcccaa ataattgaaa gacatcacca tcttcttttt
    15421 caaacaactt atgttctaaa aaatgggcaa ttccatctgg aactttcacc ttttcttttt
    15481 caccataggg aataaattcg ttatcgatcg aaccataatt cgtactgaac aaaccatatg
    15541 tcttgtgata gtcattttta ggcaacaaat acacggtcaa accgtttggc agtacttcat
    15601 gataaagtgt ttcattgatt tgctcatatt ctgttttatt catttgcatt tcctcctgct
    15661 aaaaagaaga ttgcctgcaa ttcgatttgc tcagctactt gttgtatctc tttgatcgtt
    15721 acgctctcca tacgtttcaa ccattcttca tcagataatt ttgtttccgg cagccagctg
    15781 tccaaaaaag aagcttcgat tgccgcttgc ggagagtcta gagaaagcag atattggttt
    15841 ctcagcattg cttttgtctg agacagttcc aactctgtta tttcaccatt tcgcaaactt
    15901 tctaattgct cgtgaatcag atgaagtact tgatttcggt tcttttcatc gataccggtt
    15961 tggacactca tgaatcctcg gaacgtatcc acgctactag aggcataata agctagactt
    16021 tctttctctc tgacattcat gaaaagttta gagtgaggaa aaccgccaaa taaaccgtta
    16081 aagaccatta gcgcaaaacg ttctggttca tcgtaataca catttgtctg ataagctagg
    16141 ttcagctttg cttgaacgat tggctcacgt acttgtcgtt ccttcacgat attcacttga
    16201 ggttgggtat aaaacagatc tggataaact gtttcccgcg actcaaatgg taattgccca
    16261 actgcttcag ctgctttgtc cggatcaaca tcgccgacaa caaaaatgtc gatttgatca
    16321 tttgccatca tttcttgata gtaggacgct agcgaactag cagtgatctt gtccaaatct
    16381 tcgactacgc ccaaccctgg gatcttttgt tccgggctgt tttcaaaata aagttcttgc
    16441 aaggcatagg aagcaaaagt ttgtttatct tccttcaaac tttccaaata tagacgcaga
    16501 ttgttctttt ccaagtcaaa cgtcaactga tcaaactgat gatttttaat atttggataa
    16561 aataaaacct cttttaaaaa atctaccgct tgagaaaaaa ggtttggatc attgacatat
    16621 tcaccattca caaaactgat ccctgcgttt agccaatgta aatttccttt ttttctaact
    16681 gataatccaa agcttgcgcc ataaagctct gcaagttgcg cacttaactt tgtctgatcc
    16741 ggataattca aactatttgt ttccaacatg ctgctgagaa gtgaacgttt cgtgatgact
    16801 tcttgttgca gacgcgcagt aaaacggata aaaatccgga tcgttttgta ttgttttgtt
    16861 ggtaagacat gaagattcac gccttctgcc aattgataca ccatatttat atgctccttt
    16921 tcacagttga ttgcccgctt actcttttaa tgggtcaacc tgcctttttt acttattcct
    16981 ctgcttgaaa tttataagtt caggcaattc gccgtttttt ctaaatgatg ttacacttta
    17041 tagtatagca tagatgtttt ttatcaaaag aaacagacgg ctaaaagcgt atattgtttt
    17101 tttatttttt atttttcgat atactaaaga caaataaaag aagggagggt cattcatgat
    17161 caaagaattc aaagagttca tcatgcgtgg agatgtcttg gatcttgctg tcggcgttgt
    17221 tattggtagt gcgtttacaa gcatcgtaaa ccaagtggtg caaggcttga tcacaccact
    17281 aataggttgg tttgtcgcaa tgatcacagg tacttctgat ttagaaggag cactttcaat
    17341 tcttgactgg tcgccgacaa aaggcgtcac atttgcgttt ggtaacgtta ttagtgctat
    17401 cattacattt ctgatcactg gttttgtctt attcttagtt gtcaaagcgg caaaccgtgc
    17461 gaagaattta cgctccaaag aagagcaagt ggaagtggaa gaaactccta ctgcagaaga
    17521 ttatcttagt gacatacgcg atcttcttgc caaacaagtg gcagaagaca atacacatcc
    17581 agtagagcaa acaaatcttt ccgatacttc taaataataa agaatctaaa aaaaagaaag
    17641 ccgattttca gtgtcggctt tcttttttta gattcttaac ttgctacttg ttcctttttc
    17701 atgtcgatat gtggaatatc atcttccaaa tacacatctg agattgcctt gaatccaaac
    17761 gactcataaa aagcttgtag gtattcttgt gcgccgatca cgattggttt ttctggaaaa
    17821 tttttctgga tcatgttaat cgtttcttga acaatctttc ttcctaaacc atctttacgg
    17881 ttgtcctgat gaacaaggac acgtccaaaa tggatactct ccgcttcttc atatactcgc
    17941 gtgtaggcaa ggatcttccc atcagtatct tgaaaaaacg tatgccaagc ttgtccatca
    18001 atgtcatcaa cttcttgata aggacactgt tgttccacaa caaaaactgc gattcgttct
    18061 ttgacgatcg cgtaaaactc tgctgttgac aattcttcaa atttctttac ctgatattcc
    18121 actaagcaaa cgccccctgc ttttttattc ttagcatacc gattcgcaca caaaaaagca
    18181 aacgaacctt acgaatc
//
LOCUS       DAFLWQ010000058        18035 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.059, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000058 DAFLWQ010000000
VERSION     DAFLWQ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.059"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(24..722)
                     /locus_tag="L1V16_001943"
     CDS             complement(24..722)
                     /locus_tag="L1V16_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HBN1276282.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(715..2067)
                     /locus_tag="L1V16_001944"
     CDS             complement(715..2067)
                     /locus_tag="L1V16_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HBN1276283.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2290..3690)
                     /locus_tag="L1V16_001945"
     CDS             complement(2290..3690)
                     /locus_tag="L1V16_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBN1276284.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3851..4588
                     /locus_tag="L1V16_001946"
     CDS             3851..4588
                     /locus_tag="L1V16_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HBN1276285.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4713..5192
                     /locus_tag="L1V16_001947"
     CDS             4713..5192
                     /locus_tag="L1V16_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HBN1276286.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5189..5956
                     /locus_tag="L1V16_001948"
     CDS             5189..5956
                     /locus_tag="L1V16_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276287.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6186..6755
                     /gene="lepB"
                     /locus_tag="L1V16_001949"
     CDS             6186..6755
                     /gene="lepB"
                     /locus_tag="L1V16_001949"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBN1276288.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6859..7461)
                     /locus_tag="L1V16_001950"
     CDS             complement(6859..7461)
                     /locus_tag="L1V16_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBN1276289.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7567..8036
                     /locus_tag="L1V16_001951"
                     /pseudo
     CDS             7567..8036
                     /locus_tag="L1V16_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8142..8726
                     /locus_tag="L1V16_001952"
     CDS             8142..8726
                     /locus_tag="L1V16_001952"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBN1276290.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8729..9802
                     /gene="prfA"
                     /locus_tag="L1V16_001953"
     CDS             8729..9802
                     /gene="prfA"
                     /locus_tag="L1V16_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBN1276291.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9795..10634
                     /gene="prmC"
                     /locus_tag="L1V16_001954"
     CDS             9795..10634
                     /gene="prmC"
                     /locus_tag="L1V16_001954"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBN1276292.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10627..10806
                     /locus_tag="L1V16_001955"
     CDS             10627..10806
                     /locus_tag="L1V16_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276293.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10828..11853
                     /locus_tag="L1V16_001956"
     CDS             10828..11853
                     /locus_tag="L1V16_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBN1276294.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12044..13288
                     /locus_tag="L1V16_001957"
     CDS             12044..13288
                     /locus_tag="L1V16_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBN1276295.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13441..14388
                     /locus_tag="L1V16_001958"
     CDS             13441..14388
                     /locus_tag="L1V16_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1276296.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14522..15151
                     /gene="upp"
                     /locus_tag="L1V16_001959"
     CDS             14522..15151
                     /gene="upp"
                     /locus_tag="L1V16_001959"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBN1276297.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15290..15532)
                     /locus_tag="L1V16_001960"
     CDS             complement(15290..15532)
                     /locus_tag="L1V16_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276298.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15653..15725
                     /locus_tag="L1V16_001961"
     tRNA            15653..15725
                     /locus_tag="L1V16_001961"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15686..15688,aa:Thr,seq:cgt)
     gene            complement(15844..16482)
                     /locus_tag="L1V16_001962"
     CDS             complement(15844..16482)
                     /locus_tag="L1V16_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBN1276299.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(16605..17237)
                     /locus_tag="L1V16_001963"
     CDS             complement(16605..17237)
                     /locus_tag="L1V16_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBN1276300.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            17588..17887
                     /locus_tag="L1V16_001964"
     CDS             17588..17887
                     /locus_tag="L1V16_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBN1276301.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT         6180 a         3155 c         3560 g         5140 t
ORIGIN      
        1 tcacattccc ctttttcgaa taactaggct gtttgtcctt caagataggg cagatccaat
       61 tctttaccgt aacgttgttc taaagctagg cggatcaaac gagctgccag gttctcattt
      121 cttgcaagga taggtccatg gaaataagaa ccgaagacat ttcggtaaat gacaccttca
      181 gattggtctt caccattatt tccttgacct tgtaccactt tccccaaagg tcgttcacct
      241 tcacctaaga aagtccgacc attgtggttt tcaaatccat aataagtttc attgaattct
      301 tcgttatgga taacgatatc accgataaac cggttatttt cctgacttaa cgtgtagtga
      361 tccagtgcac tgattccttg gatcttttct ccattagctc ccatgtagta gtgacctagc
      421 aattggtagc caccacaaat ggctaacatg acgccatcat tttcgatata gttgatcaaa
      481 gaatctttct ttttctggat gtcttttgaa atgattaatt gctcaaagtc ttgaccaccg
      541 ccaaagaaaa ccaagtcata tttatcagca tcaaaaggtt catgtatact aacgatctcc
      601 gtatggcaag aaacccccat tttttctgct atatatttca acatcaaaag gtttccgtta
      661 tcaccatatg tgttcatcaa atttccataa aggtgggcga tattgagttc ataattagcc
      721 acggttcatt cctcctttga taaatccttg agcagctagt tctttacgaa gctgcaatac
      781 agcagtgtaa gtagctaaaa tatagacatg ctcagttggc aattctttga ttttttcgat
      841 tacttctggt aattcttttg tttctgtcaa tttattttct ggaatcccgg caacttttag
      901 acgtaaagtc atatctgtat gacggtctcc tccagaaata acagctggga tatccatatc
      961 ggcaaagttt tcaaaattac catcccaaat ccagctgaca tcgattccgt ctgcgtaatt
     1021 ggcatttaat aaagccacta aagaaaatgg ataaggagct agaccaatca tatcgattac
     1081 ttgattgata cctacaggat ttttgacaag tactaatgta cattttttcc cattgatatt
     1141 gatgacttct tgtcggccga atactttctc gtcatatcct aaaccttgtt tgattttatc
     1201 aggatcgaca ttgaagtact ctgccactgc agtagctgct aaagcattgt agacattata
     1261 cataccgcca acttcgattc cgtattcatg accatcgatc acgaaatctg ctgacacatt
     1321 gtccatccgt accatatcag ttaatcgata atccaattca ggacgtttga agtcacaatt
     1381 tggacagtaa tatttcccta agtttgcata agtgatcatt ttataatgca agatgtgatg
     1441 acaatttgga cataagacac cgtctgtatt gtaatgagcc atttgttcac gatcttcttc
     1501 atggtcaaag ccataatatt ttctaggatt gactgtttcg atagaattga agattggtga
     1561 atcaccgtta ctgataatcg ttgcatttgg tgactttgcg gcaccgtcta caatcatttt
     1621 ataggtcgta tagatttctc cataccgatc catttgatca cggaaaatat ttgtaaataa
     1681 gaacagttct ggtttcatat attctgtgac tttgctcaaa cttgcttcat ctatttctag
     1741 gacagcaaac tttttctgtc ctttttttgg ttttgcctgc aagaaagtcg atacaattcc
     1801 ctgtaccata ttcgcaccag tagggttggt tagaacttca tcgaattgct ggcgcaaaat
     1861 attgactgtt aaagcggtag tcaatgtttt accgtttgtt ccggtgacaa cgacgacttg
     1921 gtagtctttt gccaaactat ctagtatatg tggatcgact ttcagcgcta gtttacctgg
     1981 taaacttgat ccgcctttaa aaaaagtttt taatgcccat tgcgacgttt ttccaactgc
     2041 aatcgcaaaa tgactgcgta ttcccattat gtaacctcca aaaacgattt gctgacgaat
     2101 aaattcaact aatcatacca tatgttgaaa aaaaggttaa attgcttttc ttattcttaa
     2161 gaaaaggtta cggctgaaag tgcatgaaat cggacaaaat cgcatgattt aacaaaaaaa
     2221 cagcttgaaa caaaatgatt gtttcaagct gctgtgattt tattattccc tcttacctat
     2281 attcccattt taaccgataa taattttctc gcttggatat tcatagccta gatctcgtgt
     2341 ttcttttggc acgaataaca tcaatgtata tagcattccg atccgcccaa taaacatcag
     2401 tgtagcaatc gtgattttgc ccacaacaga caagtctccg gtaatcccta aagataaacc
     2461 agttgttcca aacgcagaag ttacttcgat gatgatcgag atcagcgttt gttcttctgt
     2521 agcagataaa aaaacgatac aaaagaaaca cataccaaga gaaagcataa agacaacgac
     2581 tgattttcgc acatcatctt gatcgattct ccgtccaaaa atattgatgt tatcttcact
     2641 tttgaggaag gaatatagat acaaaccgat gattgctaca gtagttgttc gaatcccgcc
     2701 gcctacagaa ctaggactgc atccgataaa catcagtaaa gaaaaaatga tcagtgttgt
     2761 gatttgaaaa tcacccaaat cgtgaatctg cagaccagca ttacgagtcg taatcgaata
     2821 aaacatcgaa ttgatccatt tgacactcat attggaatct tggaataaat ggtccttttc
     2881 caatagataa atcaagacag ttcccgaaac aaacaagata acaaaagcta acacagctaa
     2941 tttggtaaac aaggaaaaac gaaacggaag cttcgcattg gaacgtttgt ataatagcca
     3001 ttcccggcac tccatcaata caggaaaacc aattcctccg acaaaaatca aaaacatgat
     3061 caggatcaag aaaaaatagt catgtgcaaa gggcttgatg gaatccccag tgacgtcaaa
     3121 cccagagttc gtgacagccg atatcgcctg ataaaaaccg taaaaaacgg catcacgcca
     3181 acgatcaaaa tagcctctgt aataaaaata aatagaaaag aatgtcccaa aaagtaattg
     3241 aaaccagatt aaaatagcaa aagtgatccg aatcagtcgg acgataccag acaaacgcgg
     3301 ttgattcata tccgtcatga tcagctgtcg ctgtttcagt gtgatccgtc gtttagaaaa
     3361 aatgacaaaa gcagtagaaa tcatcatgat ccccaaacca ccaacttgaa ataatatttc
     3421 cagcagtata ataccgttat cattgaacac agaattgata tcaaaagtcg atagtccagt
     3481 cacactcact gtactgattg ccatgaacag catgtccaca aaagaaacat ggctatctgg
     3541 ttcgcgaaaa atcggcatat aaaatagaac gagtgataag accgtcatca atatataata
     3601 aaaaacgatg atttggatcg atgagaaatg attggcagca aacttctgtc ctcgccgctg
     3661 cagccttcga aagaataaat caacatgcac agtactatcc tcctgacaat agtcgtttct
     3721 accagtatac aaggggaatt aggaatactc aaagaaatta tcaaacagat aacaatacag
     3781 ctttcgatta aaatagaaat ggcttataat aaggaaaatc ctagaaaaaa gaaggaggag
     3841 gaataacaaa ttgattaatg ctcaacaaat cgtagaaaaa atgaaaaatc aaaaaataaa
     3901 ttatgataca gttctgaaaa aaatgatcat gcaatgggag aaagaagaag taaagcctaa
     3961 gatattaata catacatgct gtgctccttg cagtacgcac acattggaat tcatgtctca
     4021 atatgcagag atcacgttat ttttttcaaa ttcgaatatt catcctaaaa gtgagtattt
     4081 gcgaagatta catgaacaaa aacgatttgt agaccaattt aatgagaaaa ctgaccatca
     4141 tgttgcgcta atcgttgatg aataccgtcc aaatgaattc accaaaatgg ttttaacaaa
     4201 ccatcttgaa aacgaaaaag aaggtggtgc tcgctgcagt gcatgcttca atatgcgatt
     4261 agatcttgtt gcgcaaaaag cgcaagaact aggatacgat tactttggaa gtgccctgac
     4321 catctcgcca aagaaaaatg cagctttgat caatcagatc ggaatggata tccaaaagat
     4381 ttacgggaca caatacttgc caagtgattt caagaaaaac aaaggctatg aacgctcttt
     4441 gcaaatgtgc aaagagtatg atatttatcg ccaatgttat tgtggttgcg tgttcgctgc
     4501 caagcagcaa ggatgcgatc tgaaagaaat caatcgggaa gcaaaagctt acttaaaaac
     4561 atcaaccgta gtttttgagg aaaattaaag aaatctttcg gaaaaacgta agaaaaaaat
     4621 aaagaattta tggtagaaat aaggtagact gtataatttg tccgtagtaa agtaaggaaa
     4681 caagaataaa tttcaatgaa ggaagagata agatgcgaaa agtagcacct attttgaagc
     4741 caatcgctgt attaacaatc tcgacgattg tcgcgactac tacaggtatt gtgaatagtt
     4801 ccagctaccg tgcaccaagt tcaagttcta gtactgtaga agaaacaaca ccaactactt
     4861 cagtctcgac atctgaacca acaacaacgg aaagtttgaa tgaaaccact acgacaagta
     4921 catgggacga tacaacaact agttcgtcgt atgatgagac atatacaact gacagctcaa
     4981 gcgaaacaag taatacggta ccagatggca ctccatcgga ttcaaccaat ccaagtacaa
     5041 gtccggatac aagtgctagc tccgaaacga taccaagcag tacgactgta gatgataaca
     5101 cgcaaaatga tgatgcagca cgtacagcac agcaaaacca agattcagga aatacccaaa
     5161 cgtataacca gcaagcaggt gattctcaat gacattttta ctagacctta tcaacggggt
     5221 gcataaattc cttggctatt tagacatcag tcctaaatat cttaaccgtg gatatacgat
     5281 tttaagtgtg attcccacgc tttatttatt gagaattgtt tatggacttt ggcaaaacca
     5341 aaactatctt caatttttct tatatggact tgcatttcta gtgcttgttt attttactgt
     5401 tttaaatgta ttttattact ttttagataa aaacacgaaa gccgatgtca ctcagctttt
     5461 tgtgaagtat ttacctgatg aagcgttcaa catccagaca gaagaatcga tagataatgg
     5521 aaattcgatc gataaagtga atacacaaga ggtcatggtt tcttatgacg aagattatca
     5581 attgaaatta gccgagaata tgcggtattt gattggaaat ggtgagatca aaacaaatga
     5641 actcggtcgc atggatggat ttctggtcga tagaaataca ttgtatcctt attactatgt
     5701 caagaaaaca ggagagaaag agtatgttct aaatattgga cgaagctact cggacatgga
     5761 aaaagtaggg accattcgac ttgactcaac agaagacaca ttggaacctg tcggattgtt
     5821 catcgtcggc ggtgattttg tcaaagacgg gttacgctat catgagcctt atcgtctgaa
     5881 attgattgca aaaaaggcac agtcgcagga agaaccagtg gtttatagtc gtagccaaag
     5941 aagaagacat tcataatgtg atgaaacgcc gtgtatcagt ggttgcgata aaaacgttta
     6001 ttcggaataa gggggatgtg acacgtcttt tgtcacgttc cttttttata taacgagaaa
     6061 gataagacga acacatcact tattctttcc tttcatttat aaacattgta gaataaagaa
     6121 agtacaacga agtattgtga aaaaacgtaa taaataacga ggaaaataca agtaggaggt
     6181 aagctgtgaa agaatttttg aaaaattggg ggattttgat ccttgtatta gcggctattt
     6241 tattagctag agtgtacgtg tttacaccag ttactgtaaa cgggcattcg atggacccta
     6301 cattaagtga tggacaacga ttgatttcat ctaagatctc aaactatgaa cgaatggata
     6361 ttattactac aaaggaaccg ggggatgaag aacggatgat tgttaaacgg atcatcggta
     6421 tgcctggaga tacagtcaag atggaaaatg accagttgac cattaatggc aaaaagtatg
     6481 atgaacctta tctggatgag ttcaaaaaag aattttcaga agataagtta caaggagaat
     6541 atgcttatag ctcaggattc caagcacaag cagaaagttc atccaccttt acgagtgact
     6601 ttgaatatac tgtgccaaaa ggaaagtatc ttgttctagg cgataaccgc ttgatttcaa
     6661 aagacagccg aatgtttggg ttagtcgaca aagatatgat ccaaggaaaa gttgttttcc
     6721 gttattggcc tctttcagaa attaaaatca tgtgatgaaa aaataaaaag aagctgtgac
     6781 atgttttttg tcacagcttc tttttccgaa aattccttct tatttcttgg agttgctcac
     6841 tttttttgca atctcatttt aagctttttg gctgatggat aagaaaagcg aagcgttttt
     6901 gttcataaat agcttttccc cacgatggaa ggtatgacta gtagcagaga caaagcccgt
     6961 tttttccaat cgattattca attcttcttg gctaaagcca ttatggactt tcggatgact
     7021 aatttgttca ttcttgtcaa agtctacgat gatcaattga ccgccaggag ctaaaatttc
     7081 ataaagtttt gtaagaatat tctccgtatc aggaatgtgt aaaagtacaa gtgatagaag
     7141 gatgagatta gcttggacag caggaaattc gacagaagca tcagcgtgga tcgttcggac
     7201 atttttcaga tctgctgctt ggatcttttc ttctgccatt ttcagcatag tttctgaagc
     7261 atcggcaatg atcagttctt tgaatctttc cgcaagcggt aaactaacaa gcccagttcc
     7321 gcctccgtaa tccagcagga ctttttggtg gctgtcgcgc ggtagataag tagttagttc
     7381 ttcgcgaata atcttggcta atgcttgacg gtcaggggaa tcataatggt tagcgatgga
     7441 atcaaaaata ttttttgtca tcaaatagct ccttacgtaa aactttgaaa ttttaactta
     7501 ttatagcacg tgaaaagaaa gaaagcatgc tatactcaat tcaaaaaggg agaatctaga
     7561 aagaatatgc cgatatcgtt tgtaaaagat agagaggaaa aaggaaagtg tgtccgagaa
     7621 atattactag acttgcctga gtggtttggg cttcctgaat caacggaaaa atatatcgag
     7681 gaatcaagta aactaccttt atggtgtgaa aaaagaaaag aagaatattt aggctttatc
     7741 actctttcac agacaagtga agatactgcc gaaatctatt ctattgtatg ggaataaaaa
     7801 aagactatca tcaccaagga ttaggaacaa aactttttaa agaagcagaa ggttacgcag
     7861 caaaacatta caaatatttg caagtgaaga ctgtagacga ggggcactac tctatatatg
     7921 atcaaactat ttgtttctac gaatcattag gattttcaag gttggaagtt tttccaaatt
     7981 tatgggatga atggaaccca tgtttagttc ttgtcaaaaa attggaacaa aagtgagcaa
     8041 tagatttaat actaatctgt gcttgatgaa aattctcact gtaaaaaatg ctgaaaatca
     8101 agtataatac cataggaaca aactggaagg tgaaaaagag catggcacaa ctatttttta
     8161 agtatggcgc aatgaatagc ggcaagacga tcgagatcct aaaagtcgca cataattatg
     8221 aagaacaaaa taagccagtt gtcttaatga caagcggtat tgatacaaga gatggtttag
     8281 gcgttgtttc aagccgaatc ggactgaaac gtaatgcgat gccgatattt gaagaaacag
     8341 acgtatttga cgtaattcag aaaatggaaa gcaaacccta ttgtgtgctg atcgatgaag
     8401 cgcaattctt aaaaaagaaa catgtcattg cttttacgag aattgtggac gaattggata
     8461 ttccggttat ggcatttggt ttgaaaaatg attttcgaaa cgagttattt gaaggatcaa
     8521 aatatttatt gctttatgca gacaaaatcg aagaaatgaa aacaatctgt tggttctgcc
     8581 acaaaaaagc aatcatgaat ttacattata ttgatggaaa ccctgtttat gaaggcgatc
     8641 aagtgcaaat tggcggaaat gaagcttatt accccgtttg tcgaaaacat tactttcacc
     8701 catcaatgat tacagaagga gaataagcat gtacgatcaa ttacaagcaa ttgaagaccg
     8761 ttatgaagag cttggagaac ttttaagtga cccagaagtg atttctgata caaagcgttt
     8821 tatgcagctt tcaaaagaag aagcaaacac gcgcgaaaca gtcgaagttt atcgtcgtta
     8881 taaagaagta gtacaaggaa tcaccgatac agaagaactg cttggtgaaa aactggatga
     8941 tgaaatggct gaactagcaa aagaagaatt atctgaatta aaaaaagaaa aagaagtctt
     9001 agaagaaaaa atcaagatct tgcttttacc aaaagatcca aatgacgata aaaatatcat
     9061 catggaaatc cgtggagcag caggcggaga cgaagcagca ttattcgctg gcgatctttt
     9121 caatatgtac caaaagtatg ctgaagcaca aggctggaaa acagaagtga tggaagctaa
     9181 cgttaccgga atcggtggat ataaagaagt gatcatgatg atcaccggag acaacgtata
     9241 ttcgaaatta aaatatgaaa gtggtgcgca ccgcgtccag cgtgttcctt caactgaatc
     9301 gcaagggcgt atccatactt ccaccgcaac agttgtcgtg atgccagaag ctgaagaagt
     9361 agagatcgat attgaagaca aagatatccg tacagatatc tatcatgctt caggtgctgg
     9421 cggacagcac gtcaataaaa cagcatctgc tgtacgtttg actcacttac caacagggat
     9481 cgttgttgct atgcaagatg aacgttctca aatcaagaac cgtgaaaaag caatgaaaat
     9541 cttgcgtgct cgtgtgtacg ataagatcca gcaagaagca caaagcgagt atgatgccaa
     9601 tcgaaaatca gcagtcggaa ctggggatcg ttcagaacgg atccggacgt ataatttccc
     9661 gcaaaatcgt gtgactgatc atcgtatcgg attaactatc caaaaattag atcagatttt
     9721 agcagggaaa ttagatgaga tcgttgatgc attgatcatg tatgatcaaa catcaaaact
     9781 ggaagctatg caaaatgggt aaaatgacct atcgagaagt cctgtcacgg gcttcttctt
     9841 ttttagagga tcatgggaaa gaagcatata gtatccaatt tttatttttg gaacgaaaac
     9901 aatggaaaaa acttgattgg ctccttcata tgaacgaaga gatttcagaa gaagaacagc
     9961 ggttgatcga aaccgatctg cgacttctgc ttgcagatca tccacctcag tatttgctag
    10021 gatatgcaga tttttatgat catcggttaa aggtaactga agcaacactg atccctcgac
    10081 cagaaacaga ggagttagtc gaatggtgtt tagacgagac gcctggtgta ccgttagaag
    10141 tgatagatat tgggacaggg actggagcaa ttgctattag tttgaaagca gcaagaaaaa
    10201 attggcatat atctgctgtg gatctttcag aagaagcatt agaagtagcg aaagaaaatg
    10261 ctcagaaaga aggaacgaaa atcagttttt atcatggaga tacattagga ccagtaatgg
    10321 atcagcaatt tgatgtgatt atttctaatc cgccgtacat cagtcggaat gaatgggaac
    10381 tgatggatga aagtgtccgg tcattcgaac ctaaaatggc cctttttgct gagaacgatg
    10441 gattagctat ttatgaaaaa atagcagttg aagcaccaag cgtactaaaa tcaaatggaa
    10501 agattttttt agaaatcgga tttcgccaag gtgaagcagt aaaaaaaata tttcagcaag
    10561 catttccaga taaaaaagtg gcgataaaaa aggatctttt tggcaatgaa cgaatgatcc
    10621 aagtttatgg ttgaagttgt ggatgaaaaa ttttttattt gtttttttat tataaaaaaa
    10681 cacttatttg acaaggatgt aaacgacttt ttggtttatc aacaagttta tccactattg
    10741 acaaatagat tatccacaaa cagtggaaaa cttgaggata aactcagaca aaataagaat
    10801 gtatgaaaaa ggggttgtgg ataaactgtg gaaacgaaac gatatgatga aacagaattg
    10861 caagaggcag ccgaagcact gaaagaagga gaacttgttg cttttcctac cgaaacagta
    10921 tacggattgg gcgccaacgc tcttttacca aacgctgtca agaaagtgtt ttctgtaaaa
    10981 gggagaccgc aagataatcc attaatcgtc catgtcgcct cttttgaaca agtaaaagag
    11041 tatgtggaca actttcatcc ggcagcagag aagattgtga agaacttctg gcctggacca
    11101 ttaactttga tatttaagat caaaaaagac actttgccct cagttgtgac gggaggatta
    11161 tccacagctg catttcgtat accggataac aaaaaaacac tagaagtaat cgaactttcc
    11221 ggtgttccgc ttgtcggtcc aagtgcaaat acgtcgggaa aaccaagtcc aacgactgca
    11281 gatcatgtat atcatgatct acaaggaaaa attaccggga ttattgatga tggagctacg
    11341 cgaattggtg tagaatccac tgttcttgat ttaagtgatc caacagccat gcctatgatt
    11401 ttacgaccag gtgcagtaac gaaagaacaa atcgaagcag tcatcgaatc tcctgttgct
    11461 attgatcagc atcttgtaaa agaaaatgaa acaccaaaag cccctgggat gaaatacaaa
    11521 cactactcac ccgatacacg tgttctgatg gtcagagatg gcgattggtc aactgcagtt
    11581 caatgggcaa aaaataagaa gatccgtgca ggtgtcatag caagccccga aattgcggat
    11641 caagtgcgga cagatactgc agctgtttat atgtataacg acaactcagt agaagcggcg
    11701 gctaaaggat tgtttgcagg tctaagagga ttagatgaac caacacttgg attagatttg
    11761 atttttgtac aagtgtatcc agaaactgga ttggggaatg cttacatgaa tcgcttgaaa
    11821 aaagcagcag gacaaaatta ttttgaaaaa tgatcaattg gttattgtcg cattctttta
    11881 gtatgataca atgctatcaa gtaaatcttc tatcagtgaa cgaaaaacta agcgtaacta
    11941 atcgtaatag aagagatacg aatatttggc aatttgtttt tgatgggaaa aataaaattg
    12001 taggaaaata aaattgtagg aaaataaaaa ggagctgttg tttgtggtag attacaaaac
    12061 gtttgaccct gatctttggg ctgcgatcgc caaagaagaa gaaagacaag aacataattt
    12121 ggagctgatt gcctctgaaa actttgtctc cgaagcagtg atggctgcac aaggaagtat
    12181 cttgacaaat aaatacgcag aaggttatcc agggcatcgc tattatggtg ggtgtgaatt
    12241 tgtcgatatc gttgaaaatt tagcgattga ccgtgcaaaa gaattattcg gagcgaaatt
    12301 tgcgaacgtc cagcctcact ccggctctca agccaacacg gctgcttatc tcgctttggt
    12361 agaaccaggg gacacgatct taggaatgga tctttccgca ggcggacatc taacacatgg
    12421 atcaccagtc aacttcagtg gcaaaaccta tcactttgtt gcttacggtg ttgatccgac
    12481 aacagaagtt attgattata atgtggtacg tattttagct agaaaacatc aaccaaaatt
    12541 gatcgtagca ggtgccagtg cttacggacg aacgatcgac tttgcgaaat tcagagaaat
    12601 cgcagatgaa gtaggcgcaa aactgatggt agatatggca catatcgcag gattagtagc
    12661 agcaggactt catcctaatc cagttcctta tgcagatatc acaacgacta ccactcataa
    12721 aacattgcgt ggccctcgag gcggcatgat tttgacaaac gatgaagcat tagcaaaaaa
    12781 aataaatagt gcggtatttc ctggtattca aggcggccct ctagagcatg tgattgcggg
    12841 taaagcagta gcattcaaag aagcattaga tcctgcattt aaagaatata gtgaacaaat
    12901 catcgccaat gcaaaagcaa tggtcaaagt tttcaatcaa gcaattggaa ccagagtcat
    12961 ttcaggggcg acagataatc atctgatgtt gatcgatgtt cgcgagttag gtataaatgg
    13021 aaaagaagca gagagcattt tggacagtgt gaatatcact gtaaataaaa actcgattcc
    13081 ttttgaaaca ctaagtccat tcaaaacaag cggtattcga atcggcacgc cagcaatcac
    13141 tactcgcggg ttcaaagaag aagatgctgt aaaagtggct gaactagttg tcaaagcatt
    13201 acaagcaaaa gatgataacg ctcaactaga cgaagtcaaa acaggtgtac gcgaattaac
    13261 tgaaaaattt ccgttgcata aaaaataaaa atttaaattc cattagtaaa cagaaaagtt
    13321 caatgttggg cttttctgtt tattttttgg gaaaacggat tctttgacaa tatcggtgat
    13381 gctctctagt atatgaggtg taattttagt cttcacacta aatctcaggg aggaaaagtc
    13441 atgactgatc gtatctcgtt agaaaaggaa gcagtagcat tcagtgatgc aaatgcgcct
    13501 catccgcgta tctatgaact agcaccggaa gaaggaagag ttttactaga agaagtacaa
    13561 gaatcacctg tgaacaaata ttccgtcgat attgaagact tgatggtgga tactggcgaa
    13621 tggggaaaac tcaatattcg tctcgtacga ccagaaggga atatggataa attaccagtt
    13681 attttttata ttcatggagc aggctgggtt tttggcagtg ctcaaaccca tgataaattg
    13741 atcagagaac ttgcggttcg tacgaattcc gtcgttgtct ttccagaata tagtcgatca
    13801 ccagaagcaa aatatccaac agcaattgaa caaaattatg ctgtgttgca acagctgaat
    13861 aaattagcca agtcaaaaaa tctggatctc gagaatctaa tcgttgcagg agattcagta
    13921 ggtggtaaca tggctacagt catgacgatc ttaacaaaag aacgaaaggg cctcccaata
    13981 tccaagcaat tgctgtatta tccagtcaca aacgctgatt ttgatacaga ttcctatcat
    14041 gaattcggag aaaactattt tttgacaaga gaaggaatga tgtggttttg ggaccaatat
    14101 acgacgaatg aagaagagcg tgctgaaatc acagcttcgc ctttgagagc aaatataaat
    14161 gaactaaatg atcttccttc agcaatgatt ttaacgggag aagcggatgt attaagagat
    14221 gaaggtgagg cttatgcgcg caaacttcgt gatgcagggg ttcctgttac acaagtacgc
    14281 ttccaaggaa tcatccatga ttttgtcatg gtaaatgcta tggatcagac aaaggcaacg
    14341 cgtgcagcaa tggcattatc tacttcttgg atcaagaaaa aagaataagc tttgcttgtc
    14401 cgcaggaaaa cttcttttca aaaacggatt ttcttaggaa aaatggcgag tttgactagt
    14461 caatcacttg attttgtttt acaattaaaa agaaacgaca gaacaaagga gagcttaaaa
    14521 aatgggcaaa tttcaagtga tcgatcatcc attgattcaa cacaaactaa ctattattcg
    14581 ggacaaaaac tgcggaacaa aggtttttcg tgaagtagtc gatgaaatcg ctatgttgat
    14641 ggcatatgaa gtatcacggg atatgccatt ggaagacatc gtgatcgaaa caccgatcac
    14701 tgaaacaaca caaaaaacgt tgtctggtaa aaaagtagcg attattccaa tcttgcgcgc
    14761 aggtattgga atggttgacg gtatcttgga attgattcca gctgctaaag tgggacatat
    14821 cggtctttat cgagatgaag aaacattgga accacatgaa tatttcgtca aacttccaga
    14881 agacattgat gcacgtcagt tgtttgtagt agatccaatg ttggcaacag gcggatcagc
    14941 aatcatggca atcgatgcat tgaaagaacg tggcgcgtcg aacattaaat ttgtttgttt
    15001 ggtagcagca cctgagggag taaaagcttt gcaagaagcg catcctgata ttgacatcta
    15061 tacagcttct ctagatgaaa aattgaatga acatggttat atcgttcctg gactagggga
    15121 tgcgggtgac cgtttgtttg gtacaaaata agtaaatacg aaaaagggtg tgacacaact
    15181 tttgtcacat ccttttttgg tcatttttaa cgtttgatgc agaacagctt tttcacagct
    15241 ttcgtttgca tataaaaaaa ccatcccaaa aatgcagaga tggtcaaatt caaatctttt
    15301 ttagttcttt gtagttaacg attactacac ccttactttg cgtcatcaag ttcgcatttt
    15361 ctgcagtttc atcaatctca acaacagcgg aatttttcaa ttgctttgaa atcgttccag
    15421 tttgcgactt gccgtgaatt gtgaacatta cgtgagtatt gatcttgaat ttttcaccaa
    15481 tttccgatgg tacgatagtt gtatcaaatt ttccaaaagt tgccattttc ataaaacctg
    15541 cctttcacat caattatacc acgttttatg aaaaatatca tgaaattaaa ctaattttcc
    15601 atcggactct ttacaatcag ccaaatagag tatataattt cttttggata aggccagctt
    15661 agctcagttg gtagagcaac gcactcgtaa cgcgtaggtc gtaggttcga tccctatagc
    15721 tggcattaaa agagaagaca gatatatcaa ggatttttaa tccattgata catctgtctt
    15781 tttgtttaaa ggaaataaag tatgctttct tagcaataga gcatgtatta tttctataaa
    15841 aatttaggag aataaaacga ctagcaatat agctgtgaaa tcaaatatca catgaactgc
    15901 ccaacttgta atgatcgagt tgcttttaat ggcagcttgg ttgaataaca atcttgccac
    15961 cccttgtatc aaaaggatgt gtgctacagt gtgtaaaata tttccattat cataagtact
    16021 gtaatggata aatccaaaga tgattgctga caagaaacta gcgacaggaa tgctgaactt
    16081 actagaaaaa atagcgagaa aatacactga gaacaattct tctccaagta tcatgatagg
    16141 caaaataata aataataacg ggctgaaagc ctcatttatt ggattgcctg ttaaacccca
    16201 tttcaaaatt tgttgcaaaa ataccgagac tgcggcactg attactacat tgataaaaaa
    16261 atatttggct atatttttga caggagcgac aggtttcgag aacatttttt tcgtatcttt
    16321 tttaccaaaa acaagtgtaa atgctataaa tccagtgata gttaaagaaa aaatgctaat
    16381 aatggatggc gcaaatagca accctaacaa accgagtaca acgacaatag tgcccaatat
    16441 ccctttttta agttctattt tttttcctaa aatgttattc atgataataa ctcctactat
    16501 tcagtttttg aagatagagt cagtatacat gaagagttaa aataggcaat gtttttttat
    16561 ggatatttgt attgctaaaa atttatctta tatattcatt ttgattatac tacttttatt
    16621 tgtaaaaatt ttctagcaaa accaagtgct tgcaactgat taagcgtaca attttttaga
    16681 tgttccgagc gtacttcaat catttcaaag gagttgctac ttaaatcgat attttttaaa
    16741 tcagtatcaa aaaagctagc attttctaaa tcattagtag aaaacattat tttagtgagg
    16801 gaacagtcta caaaatctgc gcttgataag acagagtgct caaaggtact ttcttttatg
    16861 tttgaaccag ataaatttac atagtccatt ttacaattct cgaataacgt gttcccaata
    16921 taactttcca tcaatttagt acctgttaat ttacaattga caaatttcac gcgatgcaac
    16981 atgctttttg tcaatataca gcctgaaaaa tcacagtttt cgaatataca gtcggtaatc
    17041 tccattcttt gaaaatcatt ggaagcaaaa aatgcatact tgaaaataga tttgtaaata
    17101 attggatggc agattatttg gttttcgatg acctcttttt gtgaaaggat attatacagt
    17161 tcaaaatctt cgttttcata gatatgaaaa aaggatcctt tattcaagct tgcttcatta
    17221 actttaggaa aaatcatatt taattacctc cattttcata aagtcatatt aacaaaagct
    17281 aaaccaactt acattagcag aaaatgagat aggttttcgc ctttttcgat aacgatagtg
    17341 tcgctatctc ttgaaacgtt cttagaattg ccctgagaga cacaaattag gcgtaattct
    17401 aataaaaatc ttagaataaa aatttttact gatttaattt agaatgtttt taaaataaaa
    17461 atcgttgcca taacagtgta ttgaaaggtt ttaacaatcc agtaatgatt taaaaaaatc
    17521 tagatgtagc gtatactttg tttatagaat gtagtgggaa gaaatatatt tttgggagga
    17581 aatcgtgatg tctaaaagtg aagaaataga aaacatggta ctaaaattat atgatctcgt
    17641 tttaaatcca gagatcaaag aaaaggaacg tatacttttg atagacgcaa agacaggctt
    17701 agaaaaaggt cagtattatc ctaaagtcat aaataatttg gaacgtagtt tacgtccgtt
    17761 agcaatcagg ggagaattgt ctaaaccagt atcaccgttt tatatggaga tatcaacaat
    17821 aggaaaattt gaaaaagaat taggtcgagg aatggcttcg gcaccgatta cttttgggca
    17881 tttataaaaa cgagttattc atctcaatga attaaaaagt atagtcaatc tcataatgca
    17941 ggctaggttc atttatttga acagagtctg tattttttta ttctaaataa agaaacagat
    18001 gtttctttat attgtatttt atcctttaat taaca
//
LOCUS       DAFLWQ010000059        17995 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.060, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000059 DAFLWQ010000000
VERSION     DAFLWQ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17995
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.060"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(138..452)
                     /locus_tag="L1V16_001965"
     CDS             complement(138..452)
                     /locus_tag="L1V16_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276302.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
     gene            738..977
                     /locus_tag="L1V16_001966"
     CDS             738..977
                     /locus_tag="L1V16_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276303.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(1339..1599)
                     /locus_tag="L1V16_001967"
     CDS             complement(1339..1599)
                     /locus_tag="L1V16_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276304.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1784..2281)
                     /locus_tag="L1V16_001968"
     CDS             complement(1784..2281)
                     /locus_tag="L1V16_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HBN1276305.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(2411..3121)
                     /gene="budA"
                     /locus_tag="L1V16_001969"
     CDS             complement(2411..3121)
                     /gene="budA"
                     /locus_tag="L1V16_001969"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HBN1276306.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(3134..4798)
                     /gene="alsS"
                     /locus_tag="L1V16_001970"
     CDS             complement(3134..4798)
                     /gene="alsS"
                     /locus_tag="L1V16_001970"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HBN1276307.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(5003..5665)
                     /locus_tag="L1V16_001971"
     CDS             complement(5003..5665)
                     /locus_tag="L1V16_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBN1276308.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(5675..6490)
                     /locus_tag="L1V16_001972"
     CDS             complement(5675..6490)
                     /locus_tag="L1V16_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1276309.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(6752..7195)
                     /locus_tag="L1V16_001973"
     CDS             complement(6752..7195)
                     /locus_tag="L1V16_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HBN1276310.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(7329..7667)
                     /locus_tag="L1V16_001974"
     CDS             complement(7329..7667)
                     /locus_tag="L1V16_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1276311.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(7655..8032)
                     /locus_tag="L1V16_001975"
     CDS             complement(7655..8032)
                     /locus_tag="L1V16_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1276312.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            8256..9449
                     /locus_tag="L1V16_001976"
     CDS             8256..9449
                     /locus_tag="L1V16_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1276313.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(9615..10037)
                     /locus_tag="L1V16_001977"
     CDS             complement(9615..10037)
                     /locus_tag="L1V16_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1276314.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            10627..11082
                     /locus_tag="L1V16_001978"
     CDS             10627..11082
                     /locus_tag="L1V16_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276315.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQAAAEQASQQAQAAAP
                     EQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSKCYGN"
     gene            complement(11244..12416)
                     /locus_tag="L1V16_001979"
     CDS             complement(11244..12416)
                     /locus_tag="L1V16_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1276316.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(12622..14051)
                     /locus_tag="L1V16_001980"
                     /pseudo
     CDS             complement(12622..14051)
                     /locus_tag="L1V16_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            complement(14048..15550)
                     /locus_tag="L1V16_001981"
                     /pseudo
     CDS             complement(14048..15550)
                     /locus_tag="L1V16_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345213.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            complement(15547..17874)
                     /locus_tag="L1V16_001982"
     CDS             complement(15547..17874)
                     /locus_tag="L1V16_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1276317.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         5242 a         3542 c         3104 g         6107 t
ORIGIN      
        1 tctagagaaa ttaattcatc ctaacataaa ataattgttc actcaaaagt ttttctagaa
       61 caattaaaac agcaggcttc acattcgcta tacatttgta agaagtaata attcctgtac
      121 taaaaggcat aattgcttta attatttttt gacttctctt caaacacaag aagtagttgt
      181 gtaataattg cagaaataag gattccaata atagatataa aatttgacat ggaaacgtct
      241 ataacattaa aagaataaag tgttgaagaa agtaaactga ttgaaataac ccctccgtaa
      301 aaaatagtct gtgaatatac ccactttttt tcagaagacg tacttcgttt ggttctaaaa
      361 cctatccctg catttctact cttatcaaaa aaccaaatat ttagaagtaa taatattgct
      421 attattaaga taaaattact gtaaaaatcc aaaagctatc ctcctagcaa ctatttaaat
      481 acccaaaaaa attacctcta gataatatca tacctacgtt ttcacttata aattttttca
      541 taaaaaaagc gtttagaggc ataatcgtta atacagatgg taaccaatgt atctggtttg
      601 aactgggata tcaccctctc catatatgta ttactaagac taatagatac tataaaagac
      661 ttgatagttt tgcattgatt ttgcctaata ctgagcatag gtgtatgcta aacgatacta
      721 taaggagtgt gtacataatg aaaagaattc tgtttatcag tttatcaaat ttattgttac
      781 ttactgcttg tgggacttct gcatcaaaga acataccttc agatacgcaa atttcgaata
      841 gtatcgattc aacaatttct acaaatgaga aaaattctcc ggtagaaact tccgatataa
      901 aagtttctac ctctgcaaaa aacagggtaa agaaactgtc agcacgtctc ctttatttca
      961 aacaaactct gaattagctt cttcatcttc ttcagcaaat aatgatgata gtttcgcgtt
     1021 tactcctaac taaatgcaac ctttacaaat gctttacgat aacaagcctg agctaaatga
     1081 tcctgatatc agttttgcat tttttgaaat gattggatcg gatgatcttt ttaaaactac
     1141 tagtttgtct atccgaaaat aggacagttc tggcagtata ggtttttatc gagtttctcc
     1201 accaggcctc gttacagaga cagattctct aggcgaacct tttgaataaa tcaaaaatca
     1261 tgaacaatca ctgccaacta aataaagtgc cttcaaaagc ttggtcttct cgcttttgaa
     1321 ggcactttat ttaaatcttt atgaaactaa agtatgttca tatttgttgc tatagttata
     1381 tagatattct gttgtttcca actcataaac gtgagtatat tttgccacta cttttccgca
     1441 tttttctaat atttcattgc gatcgacgtc atgatattcg tctacgcaga tcacaacaca
     1501 attttctaat ttactgatta cttctccaat cactttttgt ttcaagccaa taggttggca
     1561 aatatatttt tttcctaaaa tgatagtttc gttattcata tttcatccat ccttaatgtt
     1621 ttttcattat ttaaaatgat aataacatta aaatatgatt atgaaaatca ataacacttg
     1681 tgattttata aaaaaataaa aaaaccgaaa aacagaaatg cccactgtct ttccggctct
     1741 ttttattctt gatttctctt cttttttgtt tcaatagacg attttagtta ttaataaatg
     1801 aaaaagcatt tatattaaaa tttgctaata aaagatctac atatttttct agaaatgctt
     1861 gatcgatttc atcataccct ttcgttactc cgcaatcgat atctaaaaca ccgattaaat
     1921 taccttcttt taccattggc actacgattt ctgattgtgc ggctgaatcg caggaaatgt
     1981 aatttgcatg ggttttgaca tcatcaacga tcaatgtttc ttgtttttca gctgattctc
     2041 cacaaactcc ttttcccatc ttgatacgtg tgcaagaaac tcgcccttgg aacggtccta
     2101 aaatcaattc attaccatcg aataaataat atcctgcaaa gacagtctca ggcaaagtct
     2161 cattcaacaa tgcagatgaa tttgctaaat ttgctaacca gttatcttct gcttctaata
     2221 atccttgttg ctgtaataat aaaatttcgt atgcatcttt tttctgtttt tctgtccaca
     2281 tgataaaaac cgctcctttt tgatctatgg agaagattat agctcagttt ttttgtaaac
     2341 gctaggtttt ctcctcaaaa aaacgagata cgtcaggtta atcaccttga acgcatctcg
     2401 ctgtcttttt ctattctgct tgttggattt ctgctgctaa atcagcataa tcaatcgttt
     2461 cgtgaacaaa agtcggatca tcaactggaa aatgctgtac aagggacgag atgcggctaa
     2521 tctcaacttt tccttcagcc acttcaaaat ccattacatg tccgccaaat gtatgtgtat
     2581 catcgataaa atgcaggtga aatcccgctg cagcaactcc ttggaataat tcaggcgtaa
     2641 agaacccgac taatgttcct tggacattgc tttgttggaa ttctggttga gactctgaaa
     2701 tttttgctag tcttctgtaa ggtttttctt gcttcggcat gatacggatg tgcatatttt
     2761 tgaataatcc agttatcttc actgccaaaa ataggttttc cccggcttct cttactaata
     2821 tgtctttttt caattgttct ccatctgcag tttttgagac agaaaaacta gtatctggcg
     2881 taaaatctgt aattgctgca tagggggtaa gttcacttcc atctaattgg gcaactgagc
     2941 catctgatct tccttgataa gctacgccat ctaaaaagat gacttcacca tcaagcccat
     3001 gcaatgttcc caatcccaga gttccttttt ctaatatatg agcaatcgtt tctgttccat
     3061 ccatcaagcc agccatcaaa gctcctaatg tcccgtgctg gtataagatt ttttcagtca
     3121 tgtcgacact tccttaatag aattgatctg gtaagattgt ttctcccaat ttctcattat
     3181 cacggtaatc aatcggaata tcaataatta cgggtccttc tgtcgcaaat ccttcttcta
     3241 aagctttttc taattcctct acacttgtag ctcggattcc tttagcgcca aaagcttctg
     3301 catatttcac aaaatcaact ggaccaaagt ctacacctga cgcccgctga tatttcattt
     3361 tttcttggaa ctctaccata ttgtagtgtc catcattcca aatcaaatga acgatattca
     3421 attttttacg taccgccgtt tctaaatcct gggcagagaa taaaaatccc ccatcgccgg
     3481 aaactgatac gatttgtgta tttggacgca ccaatgcagc agaaatcgcc catggcaatg
     3541 caacaccaag cgtttgcata ccattactga ataacaaatg acgaggttca taacttctaa
     3601 agtggcgtgc catccaaata taatgactac ctacatctac ggtaacagtc atatcatctg
     3661 ttacttttga ctgaagcgtg ttaataactt ctaaaggatg caagatacct gcttctcctt
     3721 ttgattgaac aatgtcccgc tccgttaatt ctgcttgaag agatgctaaa tattcttttg
     3781 catcttctga cacttgttga ggctctaatg aacctgtcaa taaatcaaga gtggctgaga
     3841 tatcaccgat caattctctt tcaggctgca taaaaggatc gatttcagct ggcgcttcat
     3901 cgatcacaat gatccgcgca tctttttccg cattccagtt tcttgcttca tattcgattg
     3961 gatcatagcc aatagcaata actagatcac ttcgtttcaa aagcatatct cctggttggt
     4021 ttctaaataa acccacacga ccaaagaaat gcgcttctaa ttcacgtgag atcactccag
     4081 ctgcttggaa tgtctctaca acaggcaatg ctgtctttcc aactaattgc ctgatggcta
     4141 acgtttcttt ttcacttgat cctcgcatac ctactaatag taccggtagt tttgcttctc
     4201 taatgcgttc agctaggtaa cggatatcat ctgcagaagc agaacctaat ttaggatcgc
     4261 tcaatggctt gatgacattc ccttggacag gtgcatccac tacatcttgc gggatactga
     4321 taaagctcgc gccttttttt gaactcttag ccatacgata agcattggca atcacttctg
     4381 aaattgtttc tggatcttgg atttctgcac tgtattttgt gattggctgg aacagtgctg
     4441 cattatccat gctttgatgg gtcaacttca atagatcgct tcgttttact tgtccggcaa
     4501 ttgctaaaac tgggtcacct tctgctgtcg ctgttaccaa acctgtagct aagttactag
     4561 caccaggacc acttgttgcg ataactactc ctggctctcc tgtaatacgt ccgattgctt
     4621 gtgccataaa tgcagcattt tgttcgtgac gagtcacgat taattcagga ccttgatcct
     4681 ctaattcatt aaatacacca tcgatttttg cacctggtat accgaataca taatcaacat
     4741 gatgattaat caaactttct actacagatt tcgaaccttg tttcattttt tcgtccattg
     4801 aacatcgtcc tttttatgct ttatttttaa ttattagtta gaaataatca caaataattg
     4861 atacagtttc taaacctgtt tcattcaaaa gtatagcacg ttttatttca tttgtttagc
     4921 catatgtttc aaaaaatgaa aaagaatgac agtttttaca taaaaactgt cattcttaat
     4981 tgaaagtttc aatttataaa gtctacagat ccatagttct catcaattta cgattgttga
     5041 agtaaatcaa accaaatacg atagaaggac ctagtagaat acaccattgg ggctttacga
     5101 aaaagaagag aaacaaactt gtcaatagta aaaaatctag taaactcaca taccattttt
     5161 tcaacgtata gtagaacgct atccgtagaa cttgatttgg tttcgacgct ggatttctca
     5221 cctgaaaata ccagtagttg atgctaaagg aaactgataa acaagcaagt aaaacaaaca
     5281 acggaatcaa ccattttcca taagaaaaac gtataaaaaa gaaacaatca aaaatcatta
     5341 tcacactaac tatccaagca aatagccaat aaaaaaatcc ctttagccaa aattggcgaa
     5401 acgtctttat gaacaaacgt actggtgaaa aacttttttc ttttgctaat tcttctgtca
     5461 tacctatcat cacgatgcaa cctggaccaa taaaaagtaa agaaaaaata aaggaaaaga
     5521 cattccttcc atctatcgac aaaaggaacg cagctgctat atacaagata ttgacacacc
     5581 aaaaacaaag gctacttgcc aatgattgat acaaccaata aaagaattcc atataaacat
     5641 ttttgtcaaa acgctgctct ttcataatca cctcctattc cttcattcct gatgaagcga
     5701 tcccttctac aaaatatttt tgcatcgcta aaaatataaa agcaacagga agaacagaaa
     5761 caactgaggc agccatgatt aatgcgtact ctgcatcaaa tagcccaata aacattttca
     5821 accctaactg gattgtttta ttttccgtag aagacaaata aatgaatggc cccatataat
     5881 cgttccatgt attaacgaat gtgatgatcg tcaaactggc aatcgccggt tttgtaagag
     5941 gtaaaatgat cttgcgatag attccccact ctgataagcc atcgatccgc gcactctcac
     6001 ataaagaatc tgggatacta ctgtagtatt gcttcaacaa gaacacacca aaagcattga
     6061 acgcttgtaa tagcaccaac gaccacaacg tatatgttaa acccactttt ctcatcataa
     6121 tgaactgcgg gatcatataa gactgccaag ggacagcaat cgtgccgata tatgctaaaa
     6181 ataaaatatc gcgcccttta aaatttagtt tagaaaaccc gtaagcagca aaactagaag
     6241 taaacaactg aatcaacgtg atcacaacgc ttaaaaaagc tgtattctta aaaaatgtca
     6301 ctaaaggaat acgagaccaa ataaccagat aattctctaa atgccaagtt ttagggatcc
     6361 attgaatcgg aatcgtgaac acttcattat ttgctttgaa tgaagcagaa accatccata
     6421 aaaaaggaat gatcgtcaat aaagctaata caatcagcag aatcataccc aaccattgaa
     6481 taaagggcat gttttttgaa cgaatttttg ctttttttct ttcatttcga acacctccaa
     6541 agttataatc ttcatttctt tgtaatgatt acaatccaga acaacggtta ttatagctga
     6601 ttcatttccg ttcttcttat gtttgtaagc gcttatttaa caagttatgt aaatctcttt
     6661 attttttttg atttaaaaat gaaaaaatac aaaagcaaga ctgtcatacg tctcgctttt
     6721 gtattgaaat ttcttcgatt agagatactt attactgttc aaaagcttct ttgaaacggt
     6781 gaatcaattc attgactaca ggtgataaaa tccgattctt tttccagact agcatgcagt
     6841 tcgtttcaat cattgggtca agcggaacga atgtcactcg ctttgaaaga tgacttacag
     6901 caccttctat gactaaagca gcacctacct gattctcaat tagcgcaaat acattgaaaa
     6961 tcaaattgta cgttcctgtg atcagcaact gctccttttt tatgcctaac cagtcagcaa
     7021 acattcgctg tatttctgga cgctttgaga tcaaaagagg tacattcgca aagtcttctt
     7081 ttgttatcac gtcttttttt gctaaaacag aattttctaa aatgagcaat ccccattttt
     7141 cctttcttgg taacaaaatc gtttcgtatt tctctgtatc tactggatct agcaaaatcg
     7201 ctaaatctaa caggcttttt tctagtcact ccgtgatatc atcacttgtt ccgctgtgga
     7261 tatgaaattg aacgctggga taatcacgga tcaacttttc tagtaatagt gccaatgtat
     7321 tcgaattatc agcttccaca cagccgatcg taaatcggcc gctgaataat tgtttttttc
     7381 tgttctcgaa ttcttgagtg gtttgattcg ttaaatctaa aatttcttct gctcggcttt
     7441 tttagaaaat aacctgcttc tgtcaagatc attttgcggt tttcgcgtac aaacagttct
     7501 gttcctagtt cctcttctaa ctccttcagt tgtcggctta aggttggttg tgtaagatgt
     7561 agaacttctg cggcttgaga gattgttcct tcttctgcaa ttgtccaaaa atattttagt
     7621 aagcgtaact ccatagcgat gctccttgat ttttttactt gatacattcc attttatttc
     7681 tagataacac acgatcatat ttcttgattt ttccttgtaa acgttccaaa cattcttgca
     7741 tttcagcaat ttttttcgtc aaaagttcac tttcttcaat caaaagctta cgccgctcaa
     7801 atacagttgc ttctccttcg ctagataggc gaatatattc aatcaaagac tcgatcgata
     7861 atccggcatt tcgcatacag atcgtaaagt cgacccattt taggtcttct tctgtataat
     7921 cacggattcc gccttttgtc cgattaactg gtggaatcaa cccgattcgt tcataatagc
     7981 gcaatgtatc ggccgaaatg cccttttctt cactgacttg tttgatattc atctgatcac
     8041 tctttctctt aatttcttgc cactttactt atgtatttta tttattctac aactttaagt
     8101 gtactccaag tcaatactca tttctattaa aactaagctg gattatctat atcggttgtt
     8161 tgtgtattat ttcaaataaa aaagtcttgt ttttttattc ttttttggat atacttttaa
     8221 caatttaggg aaattttagg aaaaggggta taaaaatgac aacgtatcag cgaaagttat
     8281 tattatcgac atcggcggga attgctttag agaatatgga tattatgttt ttagcttttt
     8341 cattatcttc aatgattact tcttttcata ttagtggtac gcaagcgggt ttcatttcaa
     8401 cgatcactaa tttggggatg ctcattggag gtattttttt tggcatcata gctgataaat
     8461 atggacgtgt gaaagtattt tctcaaacgg tccttctgtt ttcgattgct tctttattga
     8521 tgtattttgc ttcaaacatc tacttggttt atctctttcg ctttatcgca ggtgtaggag
     8581 cgggaggaga atacggggcg tgtatgtcct tgatttccga aagtttttca aaaaaacaaa
     8641 ttggacgagc ttcttcggtt gctggtattg gtgcgcaggt cggtgcggct ttggctgcga
     8701 ttttagctgc tgtgatcatt ccaacgtttg gttggaagat gttgtatgtc gtaggtgtac
     8761 tgccggtgtt gatggtcttg ttcattcgtc gcggcttgac tgaaccaaag gaattcaaat
     8821 ctgtacaatc tgccgaaaag aaaaccaaac ttagcagact gtttgaatca aaacatcttg
     8881 cttggcaaac atgtggcctt agtatcatgg taactgtcca aattgccggc tattttgggt
     8941 taatgaattg gctgccttca attatgcaaa atcgattagg gctttcggtt tctgggtctt
     9001 cattgtggat ggtcagtact attttaggca tgtctttggg gatgatgact tttggcataa
     9061 tcatggataa attggggcct aaactagcct tttctttgtt tttaatttgt tcatccttat
     9121 ctgtctatct acttgtgtta gcccatagcc agtggagttt ggtagcagcc gctgtgatag
     9181 tcggctactt tatcaatggc atgtatggtg gatatggcgc agtgattagt agtttgtatc
     9241 caacagaaat ccgcgcgacg gcgaataatt tcattatgaa ccttggacga gctgttggtg
     9301 gtttttcttc tatcgtcatc ggtttcttga tggatcatta tagtttaact gccgtaatct
     9361 tgtttttgag cggtatttac ctagtcagtc tgctggtctt gacaactctt actggtgtta
     9421 cagcattaag ggaaagcttg cagcattgat agttgagtct gtaaatgaca agaaagaggt
     9481 gtggcaaaag cttgcatctg cggtaataag accagccaaa tcaaaaacat gagacactgt
     9541 ttccgtttgg ctggtcgtat tacttgatgc agggcagctt tttcaactgc taatttcctt
     9601 ctatctggcg gctactattc tttgacgtcc gtcatttcaa agtactttac taataactta
     9661 gcataacgaa aaactgtgga tacactcgta tattgagcgt ctgcataatc ttccaaattt
     9721 ttctcaggat gttgatacat gaattcaatc aaatgataat tatatgattt tctgtagaaa
     9781 tgaagataaa taatgtagat tgggaagttc tcctgctttt ccatagaaaa gcgccgatta
     9841 ttctcattct tcaaaatgac cttatcagga tatttttgga acaattcttc taaatctgtt
     9901 agataattca agatagactt acttgatacc ttcaattcgt tttgtagttc ttctattgaa
     9961 caccaacgtt ctgtttcaag cagtaaatga atcattttaa ttttcttttg agaaactttt
    10021 gttaaaaaag tctgcatatt ttctcctcct gtatctactt tactatacta catacaagaa
    10081 aaaaaacgga tacaaatatc atattgtcac accgtcaata gtgcataaac ctgttattat
    10141 ttctcttttt ttcctaagta ttctattgat atgaatcatt taatcgttta ttatataaat
    10201 gtcaataatc taataataaa ataacgtaca tattttatta ttgcatactt aataacagaa
    10261 ctatagcaaa aaatcccgtg tatcaaaacg ggattagatt aagtttcctc aatcactatt
    10321 cataacacaa ttattataac aagtaagtaa acaattgaaa aggacattta ttgaaaacgg
    10381 ttgtttttta cttaaggagg aaatttagtg aaaaaattag ttgcattgtt tttggtcgca
    10441 ggaagtttgt tgagtgggtg tggtgctact acgtctacta ctcaaagcac aagttcagct
    10501 caggcttcca gcagcagtac cacgatctcc gaaagtacgg cagattcatc gaaagaacaa
    10561 gaacaaattg aaaagaaaaa agaagaagag aaacaaaaag cggaaaaagc tgcactagaa
    10621 aaaaaagtga cagaagcgga atctgctttg tcacaagctg aagcaaatcc tacaaaagaa
    10681 aactatgcaa ctgcttcagc agctatccaa gcgctacctg aaaacaaaca agagttgaca
    10741 agccgtcttg ctgcaattga ttccacaatc aaagcaaaag aagcagaaga agaacggaaa
    10801 aagcaagaag aaattgcacg acaacaagca gaacaagcgc aacaagaagc aatcgcacag
    10861 caacaagcag aacaggcgcg acagcaagca gcagctgaac aggcctctca gcaggcacaa
    10921 gccgcagctc ctgagcaaaa taatgaacaa actgtctatg tcacaccgac cggttcaaaa
    10981 taccatacac ataaatgtgg aaatggtacg tatacccctg ccactttaag cgaagctcaa
    11041 gctcgtggtt taaccccttg ctccaaatgt tatggaaact aattcaaaag ttatactata
    11101 ataataaaat tcttctgaaa cataaaaaaa tagaagctgg cgttccagat agtaaaccaa
    11161 aaatagcagt ttacacgtcc atttcgtcag cttctctctt ttttcattta gtctgttccc
    11221 tctgcttttt tggacatctt cattcattct ttctcaatca aatagtacac ctctttttct
    11281 tttcgcagtt tatatcttcc ttttttcaat ttcattgaaa actgtttcga atgtttatgt
    11341 tttacatgga ttttaagcag gagctcctca tgttgcaagc gatagttcct gccttttaaa
    11401 tcagaaaatc tcactagtcc gtattcatca gaagctttca caaatggaac tttttctcta
    11461 gtaatatagt gtttgccgtt gagcgttttt acagaaaaga ccattccttc gattggtcgt
    11521 ccgtttgtgt tctttacata aaaagataaa ggatagtttc gcttagcgat ggccaaagaa
    11581 tctaaataag cgatgagtag ccaaactaag ccgattgatc caagtagtat accgataaac
    11641 caaataaaaa atttccattt tttccattga tcaattcctt ggatcgcttt ttttgcctct
    11701 tttgcttgat aaggaatacg atgccccgtc acaagcagtc gatgtgtatt gaccatataa
    11761 ggagtacagg taagcaaagt cacgagatct ctgccttttt ggatacccaa agaatctact
    11821 tcatcaggta agaccacttg gattttttct acttgatacg ccaatgtctt tccattgatc
    11881 tggatgaaaa actggtctcc ttttttcaac ttaggcaaat ctgtaaataa ttttgcttct
    11941 gggagtccac gatgcccaga aagaacggca tgggtgtttt tcccgccagt cggataagaa
    12001 ctttcttcca ataatgacgt tcctttttgc aaaaatattt ccgttgtctg atcgaatata
    12061 ggtaagctga cattgatttt tgggatttcg atgactccaa gcatatgttc cataaaaaag
    12121 gcattactag gtaaatcttt taatgctttt gcatcaactg cttggttgaa actgcctatc
    12181 cctggtgata cgttttgctc tgccaactgt tggtttttct ttgtcatttt ttcctgctgt
    12241 ttttttattt cctctgaatt cttattcgat gcttgctttt gataatggat gatcatttgc
    12301 tgggcaagaa aatcattcag tgaatcttct acaaaaggat aagaaaagat cccgatccca
    12361 acgactaaaa tgattgccat gaagatgtcc agtattctta ttctgctttt attcatcatg
    12421 tccacctatt ttctaatatg tatatgaaga ggttgtgaaa tcagcgcctt gacctgagta
    12481 ttcgctcaac aaacggcaaa atagttcctc ctattttgcc gtttgttgag cgaataccaa
    12541 gagaccgacc acttgtcaca acctttctcc ccatttgaat cactatcgtt tatttatcgt
    12601 atgatttttg tttccaatag tttaagcttc tgtttcttga tggcgttttt tgaagtagat
    12661 cactgctcct ccaactaaag cagtacctac caagatgaat acgatgatcc ccataccacc
    12721 agttgaaggc aagattcctt taggttggtt atcgatcgtt gtttcatcag aagttgttgg
    12781 atcatcatct actgtaaatt cagtgtacgc agcttcattc ttaggtaatg cgtagccttc
    12841 tggtgctttt gtttcttgaa ggcagtatgc cccttgtttc agcccttcga ttgaaaattt
    12901 cccttctgaa tcagaaatca atttcacttc ttcccagtca gaacctgtga cttcatctga
    12961 ccaagcatat gggtattctc ctgaggcaag atttgctatt tttttcatta atttaacagt
    13021 tggatctttt gctcttagaa tagaaaattc tgcatcggct aatttttctt gcgtgttcac
    13081 atcttgtttg atgaagtgga aatcaccgta gttttggaca ttttctacag taatcgtgtt
    13141 atccgtagtt gtattttccc gattgactac accgtttgga ttcccaagat tggcttcatc
    13201 tgcgccatgg atgataccgg ttgtttgttg caattttccg ttttttacta taaaagtagt
    13261 ttctttttgt ggattggtta attgataacc atctggtgct tttgtttcaa ctaaagtata
    13321 attgccgtct attaatccat tgacactgat ggatccttca gtatcagttg tgaatgtcaa
    13381 cgctgactca gcaggatcat agagagcgac accagtgttt tcatcaaaac cggtcacgaa
    13441 ttgattctct gaatttttga tctggaattg cgcccctgct aacttatcta cccctgaaaa
    13501 gttcccagct ttctggattt tgatattgct ttctttgatg acatttttag catataggtg
    13561 aatcgtgtct aaaggtttgt cagggtctga tgaattcggg ttataaaagg gtaagcttaa
    13621 cacgatattt ggcgacgttt cgacaccggg ctttggtgtt tctacaaaga cgtatacagc
    13681 atctttccca tcagatttac ctggaagagt caggttagct aatccttcac cagaagtcgt
    13741 tacacttgcg aagggtgtag cgtctgctgg aactgctgtg tctttacttg gatagtacgt
    13801 agcagtgatg tcatatacgt tgaattcaac gccgttcaac ggttcgctat tcggaaatgt
    13861 caattccgtt ccgttgttta tttgattttc tggtgctgaa gtgaatttca atttatgcaa
    13921 attaaccgta acattttctg gtgtaggtga tacggcctag aaacctctgc agttcctagg
    13981 ccgagaacga aaggaagcag catgatagca gttcctaaaa acgtccatat ttttgttttg
    14041 atgtttttca ttttatttcc ctcctattgt ttcctttttg ttgtttttta taaaaccaag
    14101 ctgtccctgt tgaaaggact agcaacaacc ctaaaattga gaaacctcca agcatctctt
    14161 cgcttgtttt tggaaagctt cctccatttt tttcatttga tggaccattt gtctgcatct
    14221 gaactggcgt ttttccatta ttcgtcggat ttgcttttgg ttcgttgatg atttccaatg
    14281 gtataggatg aagcggatca taactgcctt tttcaacttc aaagagaatg gttgattgac
    14341 tcaatatata tcctttaggc ggtttaatct ccactagttc gtaacttcca aaagacaatc
    14401 catggacaga aaatgttcca tctttactgg aagtaaaaat cgttgctctt gaatcatctt
    14461 tggctaccca atgatttatc ccgttttctt gcgctaagta ttggtcattt tttttgacta
    14521 gaaattgagc atctgctagt ttttgtttcg tttgccgatc cactttgaca aattgtttgc
    14581 ctcctgtttg gatggcaaga tgtgtttcta ctgtttgatt gtcagtcgtc aaacgtacat
    14641 cgttatcaaa tgtcgttttt tcactgtttt ctttcaatgt catttggtaa cggatcgtta
    14701 attttttccc agcaaacgaa ctaagatctt ttccagaatc tgataagaca aaaccatgtt
    14761 ttgttttttg tgtgtgaaat gtatgaatct tgtctccacc aatcaaaaaa tcgatcgttt
    14821 ctggttctag ccataactga ggatcagctg tatctttgat cgtataggtt cctatctcgt
    14881 tgatgttctc aggaattgtt acggtgatga gataaggaac tttatcccca tctgcaaaat
    14941 ctgtctgctt attctctact gtttttgtta atgtgagtgc agcaggtatt ttttgttcgc
    15001 tctttggata caagtggatg gtcgtcaatt tatgattaga tgaatctgtc acaggaagca
    15061 caacgacaaa tggtgctgat ttttctttta cttaatctga agtctttatt tccgcaaatc
    15121 ggtaaacagc gtcacgacct tgctcatctt tgtccgatgc actaaaagaa gcaatgccct
    15181 cttcctcgtc tactgttttt gtcacatttt ctgccagtat tttttcacta tcactttttt
    15241 gtgctagttt tctttgtgcg tcttccacac tacttccttc tgaccgcagc ttgtaaaatt
    15301 catccgagac atcatatata gcgaaagtaa cgccgttcaa cccttttact ccttgaaagt
    15361 tatccgggat atttattccg tcgttttgac tgatacttgg catcttatcg ctttcgaaca
    15421 ttcgattatg caaagtaaat gtaataggtg attctctagc tgacacagtc ggagaaccta
    15481 taaaaaagac cagtaggata aaaaagagaa cagcaaatat atccacacgt acattttttg
    15541 tttttttcat cgctgttcac ctgctttttt cttacgatgg ataaaataaa agaagccaga
    15601 aaaaataaag atcagtccta aaaagacaaa gggcagtaga cctatcccac ctgtcgaagg
    15661 aagcaagaga gtcggattga tcgtcaactt agcggtatct gttgcgataa tcgtataatt
    15721 attgtttaca cttccttcgc ctaaactaat cgttactatt tgtgatccaa tatctgtccg
    15781 gctgttaact gttagggtat aatccaatga ttcgcctaag acaacaccgg taacgtggag
    15841 atttccaacc gaaatcgagt gactttgggc atcataatta aaggcagcgt catcgacagt
    15901 aatcactgcg ttagctttat agatggtata agttcctgat gtgttggcta tatcagtaaa
    15961 tgacaacttg ggatttgctg ctttgacttt gtctattccg ctattcgtta gtttaattgt
    16021 atagctgcca gcattaacca tattttttgc tgattgtgca tctgctgtgt aatccatact
    16081 gctaagtgcc acttgtactg gagtaagcga actagtgaca ccctctgcta gcttgacatg
    16141 gattgacggg acacctgctt ttccatcata tgtcttactg ccactgagct ctaccgcacc
    16201 gctgatttgc ttaatcgtat agacatcaga tgtctgcacg atagtaaata aatagtttgt
    16261 tctggcagct agtttagcta gtccgctttt tgtcaattgc caagacgtat aggttccaat
    16321 ttcagtaggc gcagttactt caactccctt ttcattcatc gctttgaaat cagttggatt
    16381 ccatgtgatt tgatcaatac tgagatcatt gtttaaaagg gatgttgatt ctgttttatc
    16441 attaaaggca tatttaacga tcggtacaac agaaagacca tcatagtact tactgccatt
    16501 tgcattgatt gatactgttg catttgtctt ataatatagg atgacttcag aaatctgttt
    16561 tccatttgcg tcctttacga ttacatttcc atttgtatct aaactagcta aaacactcat
    16621 tgctgattgg ttctttgttt ctgtcgctga aacagctgta aaggtatatc cgttgatagt
    16681 aggcgtatta gtcgtcaggt cttgtgcagc acttccgtaa gtaagattca ttattttaga
    16741 aggagcaatc atctgtccaa aatagtcttg atacttaata gtgattggtg tttgtttgcc
    16801 tgtataggtc accgtatcga cgttactttc tagggctgtg aaagaaccgt ttgtttgtgc
    16861 aaaagaatag cccgttactg ctgttggagt gataaccact ttgtcaccca catggattcc
    16921 agataatgta gtcccgtacg ttccgatttt tgctgctcca ccattgactg tataagaaaa
    16981 agttcctgtc cgattcgcat tgacctgaac cgttgctgct tgataggttg gaaaatttga
    17041 aacatttccc ttaccatcaa cgatctgccc atttttgatc gagtaccccg tgaatggaat
    17101 atcatttgct aactgtatac cgattgaaaa agtactcata cctcctccgg caggaagccc
    17161 tccccatgtt gagggtgtaa aagaataact tttatccgca ttgggtgtaa ctgaatcgat
    17221 cgtatttcca gcggtagcca cccccatata gatacttttt gggaatgtga tagtagtacc
    17281 atttactgtg gagccaataa acagattatg gatatctgga cggttatcaa taaaagcgat
    17341 tgctttggtt acgccttgta acgcagtttt atccgcactc atcgatccgt taaccgcaac
    17401 aatgactcca tctttggcat atatcactgt atatccatct ggtatggtat gtccgttgaa
    17461 attcgcagtg gccgcaacag tactaaatgt ctggcttcta cctgtttctg aataagcttt
    17521 ctcccctgct gcttttgctg ctgtgatttc tttttctgtc ggatcaatca gttgagtcga
    17581 ggatgtggtt gaggttgtct cgttgttgct agactgattg gtgctttcta tggactgtat
    17641 ttcagaatag ggtggactat ttgtctcctc tgtcgtttgg ttagcaaaat ttgacgtttc
    17701 tgtataaacg tttacataaa tacttgataa gctccctaag aaagtaaaaa tcaagatgat
    17761 cgaaatcata atgggatgta agtattttct tttagataca gctttgagtc tagaaacaaa
    17821 atgtttttga catatacgtt ggattttatt ttgagttttc ttaatcattt tcatccctcc
    17881 tctcaataaa aaatcatcaa ataatccttt acacgttatt ctaaatttaa tttttattat
    17941 tttattgatg tatagaaagt ttggggcttt ttttctcttt ttattctaag gttat
//
LOCUS       DAFLWQ010000060        17310 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.061, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000060 DAFLWQ010000000
VERSION     DAFLWQ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.061"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..99
                     /locus_tag="L1V16_001983"
     CDS             <1..99
                     /locus_tag="L1V16_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBN1276318.1"
                     /translation="DSYIYYYNNERIKQKLNWQSPVQFRKTTVTVV"
     gene            complement(394..1527)
                     /locus_tag="L1V16_001984"
     CDS             complement(394..1527)
                     /locus_tag="L1V16_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1276319.1"
                     /translation="MLLNFKMTLTMLAFSLLVTGVILVSFFFLRNNLEGISIASTLGE
                     DVYFMEEGKTVQAETQMEASKSSNNQFMTISMIDKAYQDELFKYLPAMVLVICSAVML
                     LTFILWLVLRKIYSNQILAITRDLTFIDQVPKNTVKDEALNAAFNKLKDKFDGHLEDY
                     RRLNSYLTHEQKNAIAILRTNLEIERQHADQGNLMLLDRMTDSIDDILTLSNNSEDLS
                     TEVVDVSLICAEVCDAYKMNYPNLLFAFTEDQPTLIHGRDRWIYRAVSNLVDNAIKYG
                     EGKLVIVTISNQKGSVIIEVKDQGIGIPQEKQASIFSHQYRVHGLKQDGLPKTMDFRD
                     TDETFIQSVASKRNHIPRKSLNYRTPLEVFLSCIDKDILSSLI"
     gene            complement(1518..2186)
                     /locus_tag="L1V16_001985"
     CDS             complement(1518..2186)
                     /locus_tag="L1V16_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1276320.1"
                     /translation="MRVLVVEDNRELVLSVKKGLEQENISVDVAYDGESGEEKAFINS
                     YDGILLDLNLPKKDGLSVLQSLRAEEVESPVIIITARDEIEERAKGLDFGADDYLVKP
                     FELLELKARIRAVIRRYHGRALPQISIGALKIDPLGRRVSYQKTEVVLKPKEFDILLC
                     IAQRHPAVVSSEEISEHVYDEDFDPFSSVLRVHLARLKKKLAEAAEKEVLKTIRAKGY
                     QLCY"
     gene            complement(2642..3628)
                     /gene="lacD"
                     /locus_tag="L1V16_001986"
     CDS             complement(2642..3628)
                     /gene="lacD"
                     /locus_tag="L1V16_001986"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBN1276321.1"
                     /translation="MNEEKRQYIKQLCNEDGVIGALAIDQRGALKKMITKFKGSEAEE
                     SEIVEFKEIVSSQLTKYASSILLDPEYGLPAADVRAKNAGLLLAYEKTGYDASTPGRL
                     PDLLSIWSVKRLKEAGADACKFLLYYDVDEAEEINNQKHAFIERIGSECQAENLPFFL
                     ELVSYDANISDATSKEYAIKKPHKVNDMMKEFSDPRYGVDVLKVEVPVNMNYVEGYGT
                     DEVVYTKAQAANFFKEQAEATNLPFIFLSAGVKAELFQETLRFAKNAGSTFNGVLCGR
                     ATWADGVESYIVDGKEAAMEWMNTQGRKNIEELNAVLKETATPVEVLTSSLS"
     gene            complement(3641..4567)
                     /gene="lacC"
                     /locus_tag="L1V16_001987"
     CDS             complement(3641..4567)
                     /gene="lacC"
                     /locus_tag="L1V16_001987"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HBN1276322.1"
                     /translation="MILTITMNPSIDISYPLETFKLDTVNRVRNVRKTAGGKGLNVTR
                     ILKQLDTEVIASGLIGGFLGEEIKKDLTQNEIAHDFLPISGETRNCIAVLHDGKQTEI
                     LENGPVITEQEARAFLQHFEKLAVKAEIISFSGSLPEGLPADFYRQMLQVCQPKPVVL
                     DCSGTALREVLRGSVKPKLIKPNTEELAGLLGREISTELSDLKAALSDSMFDEIEWIV
                     VSMGGDGAFAKHHETFYCVTIPKIDVVNPVGSGDATVAGLTAAIQQGLSDEAVLKQGN
                     VLGMLNAQEATTGYVQLANYQKLYDQILVEKV"
     gene            complement(4580..5095)
                     /gene="lacB"
                     /locus_tag="L1V16_001988"
     CDS             complement(4580..5095)
                     /gene="lacB"
                     /locus_tag="L1V16_001988"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HBN1276323.1"
                     /translation="MKIAIGCDHIVTDTKMAVSDFLKSKGHEVLDMGTYDFTRTHYPI
                     YGKKVGEAVTSGEADLGVCLCGTGVGINNAVNKVPGIRSALVRDMTTAIYAKEQLNAN
                     VIGFGARITGEFLICDILEAFINADYQETEENKKLIAKIDHVEKASDKQSDPHFFDEF
                     IEKWDRGEYHD"
     gene            complement(5114..5542)
                     /gene="lacA"
                     /locus_tag="L1V16_001989"
     CDS             complement(5114..5542)
                     /gene="lacA"
                     /locus_tag="L1V16_001989"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HBN1276324.1"
                     /translation="MRVVIGSDSDGMELKELIKKKLIKEGITVVDKSETASEDFVEST
                     LAIANDLNENEGSLGIAVDGYGAGSFITATKVKGMVAAEVSDERSAYMTRKHNNSRMI
                     TLGSKIVGDELALNIVKEFLQANYDGGRHQVRVDMLNKMA"
     gene            complement(5562..6335)
                     /locus_tag="L1V16_001990"
     CDS             complement(5562..6335)
                     /locus_tag="L1V16_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1276325.1"
                     /translation="MLKTERQRSILAMCDRYGTITVKFIQEVLNVSDMTIRRDLEELA
                     QKKKLLRVHGGAQKIDYLEMSTSIEANELSHTEKKKLHTKEKEYIAKNAAAHINQEDD
                     TIFLGSGTTIELMTRYIKPSSLRIVTNSLPVFNLLSEIKRFELYLIGGLYREKTGAFV
                     GSIANEAVQKIGIKKAFVGVNGLKGSEVSNFSIEEGTLQKIVLDNAAEKCLVSDANKF
                     DHSDFYNFYDLRKIDKLFTDSTLSAELKSYYQQFTKIIQ"
     gene            6500..6979
                     /locus_tag="L1V16_001991"
     CDS             6500..6979
                     /locus_tag="L1V16_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1276326.1"
                     /translation="MNEFFFKDTVYVSDKQSQEEVFEEVYQDLLKKELVTEDFLENLL
                     ERERNYPTGLDLSPVSKILPDIAIPHTESEFVRTTRIIPIKVKNEIPFYNMISPSDQI
                     SASFLFMILNENGEAQAGMLANIMDFINSVDEEKLFSFFKLEDTEAIYHFLEEHFYI"
     gene            7036..7338
                     /locus_tag="L1V16_001992"
     CDS             7036..7338
                     /locus_tag="L1V16_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBN1276327.1"
                     /translation="MIKILAACGAGVNSSHQIKSALETELKNRGYQVTCDAVMIKDIN
                     EEMLSHYDIFAQIANTDLGFDINIPVVDAGAILYRIPAMAEPVYQSMESAIQSLNK"
     gene            7360..8817
                     /locus_tag="L1V16_001993"
     CDS             7360..8817
                     /locus_tag="L1V16_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBN1276328.1"
                     /translation="MNTIIDIANKVFTPLINLGAAPLMTIVLTVIALFFKVKPSRALE
                     GGLKLGIALTGIGAIIGILTTAFSDAMTAFVERTGISLNITDVGWAPLATITWGSPYT
                     LYFLLIMVIVNIVMLAMKKTNTLDVDIFDIWHLAIVGLFAIFCGANLFIASALVIFIG
                     VLKIWNSDLMKPTFNDLLNAPDSNPMTTTHMNYMMNPIIMVFDKIFDKIFPWLDKYDF
                     DAAKLNSKIGFWGSKFAIGIYLGIFVGLLAGQTPTQIFSLAFTAAVCLELFSLIGAWF
                     IAAVEPLSQGITDFANKRLKGRTINIGLDWPFIAGRAEIWAAANVLAPIMLLEAIILP
                     GNKLLPLGGIIAMGVTPALLVVTRGKLIRMIVIGAIELPLFLWSGTLIAPFVTQTAKA
                     VGAFPAGLNGSAMISHTTMEGPIEKFLGYLVGNASQGQIEFVIYAALALGAYLLIFIW
                     YARQMKKRNAAYAAEKEENASPATAHNMTYAAEAK"
     gene            complement(9410..10162)
                     /locus_tag="L1V16_001994"
     CDS             complement(9410..10162)
                     /locus_tag="L1V16_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1276329.1"
                     /translation="MLKTDRFQAIMSLLEVNGTVRVSDIMEKFSVSDMTVRRDLDEME
                     KQGLLERVHGGAKLKDFYRHVELSHREKQIMLQEEKQRIVEKANEMINDGDTIFLGPG
                     TTIELMSKIIQGDSLRIVTNCLPVFEELNKRKGNRKIYLLGGEMRETTQCFVGEITNK
                     SLQDMNFHKAFFSCNALNEQKIMTSTFEEGQTQQIALNNSVERFLLIDHSKIGKRDFS
                     VYYNLNDVTVVITDDDEQKHYEKIEKEEKYVV"
     gene            complement(10377..10613)
                     /locus_tag="L1V16_001995"
                     /pseudo
     CDS             complement(10377..10613)
                     /locus_tag="L1V16_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178530.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UTRA domain-containing protein"
     gene            complement(10623..11587)
                     /locus_tag="L1V16_001996"
                     /pseudo
     CDS             complement(10623..11587)
                     /locus_tag="L1V16_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(11793..13475)
                     /locus_tag="L1V16_001997"
     CDS             complement(11793..13475)
                     /locus_tag="L1V16_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBN1276330.1"
                     /translation="MNTIIKQIEKGKPFFEKISRNIYLGAIRDGFLTAMPAILFSSIF
                     IMIAAVPEVFNVTLPEAFSTWLWKVYGYSMGLVGLLVVATTARCLANSMNRQLSDSGK
                     QINEVSVMLASICGFVMMAADQIDGGIATDYLGTKGLLAAFVSAFVTVNVYKFCVKRD
                     LTIRMPKEVPGTITQMFRDIIPFSIAVFIAVLIDTGVRQFFGTSFAAGVIQLLQPLFS
                     AADGYVGIAIIWGAMAMFWFVGVHGPSIVEPAIAAIIYANVETNFELFKNGAQASKVL
                     TVGLGNFVGTMGGTGATLVVPFLFMLFAKSKQLKAVGKASFIPVSFAVNEPLLFATPI
                     ILNPYFLIPFLLAPIANVWIFKLFVDVLGMNSFISVLPWATPAPIGLVLGTGFSVLAI
                     VLAVVLIVVDAIIYLPFVKAYDSELVEQELKNIAAEEVKEELVEEIQEVGATAAVIVD
                     EAKASVGEGKRVLVLCAGAGTSAMLANALEEGAKETGVNLSAKAGAYGSHYDMMKNFD
                     LIVLAPQVNSYLDDLRKDADKLGIKVIATKGAEYINLTRDPKGAVDFVLKQF"
     gene            complement(13486..13809)
                     /locus_tag="L1V16_001998"
     CDS             complement(13486..13809)
                     /locus_tag="L1V16_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBN1276331.1"
                     /translation="MDRKELQLLGFEIVAYAGDARSSLLTVLKEVREGNFDNVERLLA
                     DADENLTLAHNSQTKCLAEEASGNEMEVGVIFIHGQDHLMTTILLRELINDFVELYKE
                     KFAKA"
     gene            complement(13832..15238)
                     /gene="lacG"
                     /locus_tag="L1V16_001999"
     CDS             complement(13832..15238)
                     /gene="lacG"
                     /locus_tag="L1V16_001999"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBN1276332.1"
                     /translation="MNYKTLPEDFIMGGATAAYQAEGSTKEGGKGQVAWDTFLVEKGR
                     YTADPASDFYNQYPVDAELCKKFKIDSIRMSIAWSRIFPKGYGEVNQTGVEYYHKVFA
                     ELNKHGIIPFVTLHHFDTPKELFDNGDFLNRENVEHFVNYAQFCFDEFSEVHYWSTFN
                     EIYPVASNQYLIGSFPPEVQFDIEKTVTCLHNMMYAHAKTVNIFKDGGYKGEIGVVHS
                     LETKYPASDKEEDKHAAKLDDALSIKFLLDATYLGYYSDETMAHINEILAANGQSADI
                     DSNDFREMKKAANRNDFLGINNYGSHWVKEYKGESTLHYNTTGEKGSQVYCIKGIGER
                     IVREDLPKTDWDWIIYPKGLYDLLVRIQDEYPNYNKIYITENGLGYKDNFEDGIILDD
                     DRIDYLRQHFNAISDAIKMGVNVKGYFIWSLMDVFSWVNGYTKRYGLFYVDFDTQKRY
                     PKESAYWYKFVSETKTII"
     gene            15705..16712
                     /locus_tag="L1V16_002000"
     CDS             15705..16712
                     /locus_tag="L1V16_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1276333.1"
                     /translation="MVTIRDIAKKSGYSTATISRLFKGDESLSITSDTKNKIIVTAKS
                     LGYDLTKIKTTLYKIAILFWISEEQLKKDVYYQHVKDDLKNYSKKANLDLIFISKNDG
                     VKSIPDDITGFIAIGQLTKKELYYLNQKGYKGVIRGINPLPEHFDTVEPDFHEMARQA
                     INYFINEGFTKIGFIGGNFFNLETGKEEIDSREYAFRYHLEKSGLLNEKYIFSQGSFT
                     VDEGYQLTLKMKAELNEDMPEACFIPSDTIAAGVLQGCHELGINIPKDMAVISINDDD
                     IAKFVAPPLTTFKIDIEEIAKTCVDLLSDQLVYSRDISKKTLIGAKLTVRKSFIPKEE
                     V"
BASE COUNT         5202 a         3646 c         2837 g         5625 t
ORIGIN      
        1 gatagctata tctattacta caataatgaa cggataaaac agaaattaaa ctggcaaagt
       61 cccgtccaat ttcgtaaaac aaccgttacg gttgtgtaaa aatatcattt tagagcatga
      121 aaaaaagagt ggatttctcc actccaaaaa agtctaactt ttgggggtca ctacattttt
      181 gatccttttt atttgattaa ttatatccag ctggataata attttggggg caacatttct
      241 atcttactat tatcttccta aagtagtaga ctttcttatt gggaaaaatt acaacaaaaa
      301 ggagtggctt agttgacaac tcctttttgt ttacaaatca attggatatc tataaattgt
      361 attttctaac gaattttata gacatctgat ttgtcaaatt aagctagaca atatgtcttt
      421 atctatgcag ctcaaaaata cttccaatgg tgttcgataa tttaatgatt ttcttggaat
      481 atggtttctt ttcgaggcaa cggattgaat aaaggtttca tccgtgtccc taaagtccat
      541 tgttttaggt aagccatcct gcttgagccc atgcactcgg tactgatgag aaaaaattga
      601 tgcctgtttc tcctgaggaa tgccaattcc ctgatctttt acttcaataa tcacgctacc
      661 cttttggttt gaaatggtga caattaccag ttttccttca ccatatttga ttgcattgtc
      721 aactaaattc gaaaccgccc gataaatcca acgatctcgt ccatgaatca gggttggttg
      781 atcttcagta aacgcaaaca aaagattcgg ataattcatt ttgtaggcat cacaaacttc
      841 cgcacagatc agtgaaacgt ctacgacttc cgtgctaaga tcctctgagt tattggataa
      901 tgtcaaaata tcgtcaatac tgtcggtcat ccgatctaaa agcattaaat ttccttgatc
      961 ggcatgttgc cgttctattt ccagattcgt acgcaaaata gcgatggcat ttttctgctc
     1021 gtgggtcaga taactattta atcgtcgata atcctccaaa tgaccatcga acttatcctt
     1081 tagcttatta aaagccgcat ttaatgcctc gtccttcaca gtatttttag gaacttgatc
     1141 aataaacgtt aaatcacgcg taatcgctaa gatttgatta ctgtaaattt tgcgtaaaac
     1201 caaccaaaga ataaacgtta ataacatgac ggcagaacaa ataaccagca ccatcgctgg
     1261 taaatattta aatagttcgt cctggtaagc tttatctatc atcgaaatag tcataaattg
     1321 attgttggaa gatttcgaag cttccatctg cgtctctgct tgaaccgtct taccctcttc
     1381 cataaaataa acatcttcac ctaaggtaga tgcgatactg attccctcca aattatttct
     1441 cagaaagaag aaactcacta aaatcacgcc tgtcaccaac agtgaaaaag ccagcatcgt
     1501 taacgtcatt ttaaaattta atagcatagc tggtacccct ttgctcgaat ggtttttaag
     1561 acctcttttt cagctgcttc agccagtttc ttttttagac gagccagatg cactcgcaga
     1621 accgacgaaa aaggatcaaa atcttcatcg tagacatgtt cagaaatttc ctcagacgaa
     1681 acaaccgctg gatgacgctg agcgatgcac agtaagatat caaattcctt gggtttcagg
     1741 accacctctg tcttttgata gctgaccctt cgacctaatg gatcaatctt caaagcacca
     1801 attgaaatct gcggcagcgc acgtccatga taacgacgaa taaccgcgcg tattcgtgct
     1861 tttaattcta gtaactcaaa gggtttgact aaataatcat ctgctccaaa atccaagcct
     1921 tttgctcgtt cttcaatctc atcacgtgca gtaataatga taactggact ttcgacttct
     1981 tcagcacgga gactttgtaa aacagataat ccatcttttt taggcagatt taaatctagt
     2041 agtatcccat cgtatgaatt gatgaaggcc ttctcttctc ctgactcgcc atcataagct
     2101 acatctacag aaatattctc ctgctctagg ccctttttta cggataaaac cagctcacga
     2161 ttgtcctcaa ccaccagtac acgcatgtat attcactcct catacggatt tagtaattac
     2221 acttatgctt tttagcatag tacacgctct tcttcaaagt ccacgttctt tttgtgaaga
     2281 tttgaagaaa ttcatacatt ctgttaaaaa acacataatt aagaatgatt ttactgtttg
     2341 aaaataccta gaatagaaaa agactggaac ctttcctcca gtctcactac tttctatttg
     2401 cttggttttc ttgtatatac ttttcaaagt tcgttggttt atgaccaata agcctcgtta
     2461 gaatactgaa aattgccatc aagtcattaa gtaccacatg taagaaaatc tctctaaaga
     2521 aaaacccctt cgttttaact cacttactat tttagaattc gttcccctaa taatgcagca
     2581 tgattttacg ctttatgtat aaaaaaagac tgcaagcaat tttgcttcac agtctgattt
     2641 cttatgatag tgagcttgtt aacacttcca ccggtgtagc agtttctttc aatacggcat
     2701 ttaattcttc aatattttta cgcccttgcg tattcatcca ctccatcgct gcttcttttc
     2761 catcaacgat atagctttct acaccatctg cccaagtcgc acggccgcaa agtacaccat
     2821 tgaaggttga gccggcattt ttcgcgaagc gcagtgtttc ttggaacaac tctgctttta
     2881 caccggcgct taggaaaata aatggcaggt tagtggcttc agcctgttcc ttgaagaagt
     2941 tagccgcttg tgcctttgtg tacacgactt cgtctgtccc atagccttcc acataattca
     3001 tattgacggg tacttccacc tttaacacat ctacgccata acgtggatca gaaaattcct
     3061 tcatcatatc gttgacttta tgaggtttct taatggcgta ttctttcgaa gtcgcatcag
     3121 agatgttcgc gtcataagaa acaagctcca agaagaaggg taagttttca gcctgacatt
     3181 ctgagccgat tcgttcaata aaggcatgtt tttgattatt gatttcttct gcttcatcga
     3241 catcatagta aagtaggaac ttacaagcat cggcgcctgc ttcttttaaa cgtttaactg
     3301 accagatcga taataaatct ggtaaacggc cgggagttga cgcatcgtaa ccagtttttt
     3361 cataagctaa cagcaagccg gcattttttg ctctaacgtc agctgctggc aagccatatt
     3421 cgggatctaa taaaatcgat gaggcatatt tcgttaattg tgaagaaaca atttctttaa
     3481 attcaacgat ttctgattct tctgcttcgc tgcccttgaa ttttgtgatc atcttcttca
     3541 aagccccgcg ttgatcaatt gctaaggccc caatcactcc atcttcattg catagttgct
     3601 tgatatattg acgtttttct tcgttcattt ccgtatcctc ctacactttc tccactaaga
     3661 tttgatcata tagtttttga taattggcta attggacata gccagtcgtc gcttcctgag
     3721 cattcagcat tcctaaaaca ttaccctgtt ttaacacggc ttcatccgaa agaccttgtt
     3781 gaatcgcagc ggtcaatccg gcaacggtcg catcaccaga gccaactgga ttgacgacat
     3841 caatctttgg aattgtcacg caataaaaag tctcgtgatg tttggcaaag gctccgtcgc
     3901 cccccattga aaccactatc cattcaattt catcaaacat cgaatctgac aaggcggctt
     3961 ttaaatctga taattctgtt gagatttctc gtcctagcag accagccagc tcttcggtat
     4021 tgggttttat tagcttaggc tttacactgc ctcgcaacac ttcccttaat gctgtacctg
     4081 aacaatctaa aacgacaggc tttggctgac aaacttgcag catttgtcga taaaaatcag
     4141 caggcaatcc ttctggcaag cttcctgaaa aagaaatgat ttcggcttta acagctaatt
     4201 tttcgaaatg ttgcaagaac gcccttgctt cttgttcagt aataacaggt ccgttttcta
     4261 ggatttccgt ctgttttccg tcatgtaaaa cagcgatgca attacgtgtc tctccgctga
     4321 taggtaaaaa gtcatgagca atctcatttt gagtcaggtc ctttttaatc tcttcaccta
     4381 aaaaaccgcc gattaaacca ctagcaatca cctccgtatc taattgcttc aagatacgtg
     4441 tcacatttag gcccttaccg ccagctgttt tgcgaacatt tcttactcga ttgactgtgt
     4501 cgagcttgaa ggtttctaat ggataagaaa tatcaatcga tggattcatc gttattgtta
     4561 aaatcatttg tccacccgct taatcgtggt attcgccacg atcccatttc tcgataaatt
     4621 catcgaagaa atgcggatca gactgcttgt cactggcttt ttcgacgtga tcgattttgg
     4681 cgatcaattt tttgttttct tcagtttctt gataatcggc attgatgaag gcctctaata
     4741 tgtcacagat caaaaattct cccgtaatcc gagcgccaaa gccgatcaca ttggcattta
     4801 gttgttcctt cgcatagata gcagtcgtca tatcgcgaac cagcgcactg cggataccag
     4861 gtactttatt gacagcgttg ttaatcccaa cacctgttcc acacaaacaa actcctagat
     4921 ctgcttctcc gctagtcacg gcctctccga ctttttttcc gtagatcgga taatgggttc
     4981 tggtaaagtc ataggtcccc atatccaaca cttcatgtcc ttttgatttt aagaaatctg
     5041 atactgccat ttttgtatct gtgacgatgt ggtcacagcc aattgcgatt ttcatttcat
     5101 tcatccttcc taattacgcc attttattta acatgtcgac acgtacttga tgacgaccac
     5161 catcataatt tgcttgtaga aattccttaa caatattcaa cgccaactca tcgccaacaa
     5221 tttttgatcc aagtgtgatc atccgagaat tattatgttt acgggtcata tacgcactgc
     5281 gctcatccga aacttctgct gctaccattc ctttaacctt tgttgccgtg ataaagctgc
     5341 cagcgccgta gccatcaacc gcgattccta aactaccttc gttttcattc agatcatttg
     5401 cgatcgccaa agttgattcc acaaaatctt ctgaagccgt ttcactctta tctactactg
     5461 taataccttc tttgatcaat tttttcttga ttaattcctt taattccatg ccgtcactgt
     5521 ctgaaccaat tactacacgc atttttgttt cctcctattt tttactgaat gattttagtg
     5581 aattgctgat aataactctt cagctcggct gaaagagtag aatccgtaaa taatttgtcg
     5641 atcttgcgca aatcatagaa attataaaaa tcgctatggt cgaatttgtt tgcatctgaa
     5701 accaaacatt tttctgccgc attatctaaa acaatttttt gcaaggtacc ttcttcaata
     5761 ctgaaattcg aaacctccga acccttcaat ccattcactc cgacaaaagc cttcttaata
     5821 ccgatttttt gaacagcttc attggcaatt gaaccgacaa aggctccagt cttttcccga
     5881 tatagcccac cgatcaaata cagttcaaat ctttttattt cacttaatag attgaaaacc
     5941 ggcagactat tggtaacgat tcggagagat gacggcttga tgtatcgtgt cattaattcg
     6001 atcgttgtac ccgatccaag aaaaatcgtg tcgtcttctt gattgatatg agctgccgca
     6061 tttttagcga tgtattcctt ctcttttgta tgcagcttct ttttttcagt atgagaaagc
     6121 tcatttgctt ctatagaagt cgacatttcc agataatcga ttttttgtgc accgccatga
     6181 acgcgtaaaa gctttttctt ctgcgcgagt tcctctagat ctcggcggat cgtcatatct
     6241 gaaacattca gtacttcctg aataaatttg actgttatcg tcccatagcg atcacacatc
     6301 gctaagatcg aacgctgtcg ttctgttttc agcatattct gtacctccac gaccttataa
     6361 taaaacattt acgaacattt ttcaacacat attgttcgtt tattttcgtt tatgcgttga
     6421 caatgatttt gtaagcggtt atactcaact tgtaaacata taaataaaca taaacgaact
     6481 aataaaggag ctgttttgtg tgaatgaatt ctttttcaaa gacactgtct atgtttctga
     6541 caagcagtcg caggaagaag tgttcgagga agtctatcaa gatctgttaa agaaagaatt
     6601 ggtaaccgaa gattttttgg agaacctttt agaacgggag cgtaattatc cgacgggatt
     6661 agatctctca cctgtctcta aaatattgcc agatatcgct atccctcata ccgaaagtga
     6721 gtttgtgcga accacccgta tcattccaat caaagtaaaa aatgaaatcc ctttctacaa
     6781 catgatctcg ccaagcgatc agatttccgc ttcatttctt ttcatgatct tgaacgaaaa
     6841 tggtgaagca caggctggca tgttggctaa tatcatggat ttcattaatt ctgttgacga
     6901 agaaaaactg ttttcgtttt tcaaattaga ggacacagaa gcgatttatc attttttaga
     6961 agaacatttt tatatataga agtctctgcc taaccgcagg ataaaaaata aacttatttt
     7021 aaggggagaa ttattatgat caaaatttta gcagcatgtg gagcaggcgt taattcaagc
     7081 catcaaatca aaagcgcttt ggaaactgaa ttgaaaaatc gtggctatca agtcacctgt
     7141 gacgccgtta tgatcaaaga tatcaatgaa gaaatgctgt ctcattatga cattttcgca
     7201 caaattgcca acaccgactt gggttttgac attaacatcc ctgtcgttga tgcaggtgct
     7261 attctttatc gtattcctgc tatggctgag cctgtttacc aaagtatgga aagcgcaatc
     7321 caatcattaa acaaatagga ctaaagaaag gaaaagcata tgaatacaat tattgatatt
     7381 gccaataaag tatttacccc cctaattaat ttaggtgcgg caccgttaat gaccatcgta
     7441 ttaactgtta ttgctttatt ttttaaagta aaaccgtcac gcgctcttga aggcgggctc
     7501 aaattaggga tcgccctgac tgggatcgga gctattattg gaattttaac tactgctttt
     7561 tcagacgcta tgacagcttt tgttgaacgc acaggtattt cattaaacat tacagatgtc
     7621 ggttgggccc cactagcaac catcacatgg gggtcgccat acacgcttta ttttttacta
     7681 attatggtga tcgtcaatat tgtcatgtta gcaatgaaaa aaaccaacac attagatgtg
     7741 gatattttcg atatttggca tttagcaatt gttggtttgt tcgcgatctt ctgcggtgct
     7801 aatctgttta ttgcttctgc attagttatt ttcattggtg tattaaaaat ttggaactcc
     7861 gacttaatga aaccaacctt caatgacttg ttaaatgcgc cagacagcaa cccgatgacc
     7921 acgactcata tgaactacat gatgaatccg attattatgg ttttcgataa aattttcgac
     7981 aaaatcttcc cttggttgga taaatatgat ttcgatgctg ccaaattgaa tagtaaaatt
     8041 ggcttctggg gatcaaaatt cgcgattgga atttatttgg ggatttttgt tggattacta
     8101 gcaggacaaa caccaacgca aattttctcg ctagccttta ccgctgccgt ctgtttggaa
     8161 ttgttctctt tgataggcgc ttggttcatc gcagccgtag aaccgttatc acaagggatt
     8221 accgattttg ccaataaacg actaaaagga cgtaccatca acataggttt agactggcct
     8281 ttcatagcag gccgcgctga aatctgggct gccgctaacg tattagcacc aatcatgttg
     8341 ctagaagcca tcatcttacc aggaaataaa ttattgccac taggcggaat catcgcaatg
     8401 ggtgttaccc cagcactatt ggtcgtaact cgtggaaaat taatccgtat gatcgtaatc
     8461 ggcgcgatcg aattaccatt attcttatgg tccggcacct tgatcgcccc gttcgttact
     8521 caaacagcta aagcagtcgg agcctttcca gccggcttga acgggtccgc catgatctct
     8581 catacaacga tggaaggccc gattgaaaaa ttcctaggtt atttagtcgg taatgcttct
     8641 caaggacaaa tcgaatttgt gatatacgct gccttagcat taggtgcata ccttttaatc
     8701 ttcatttggt acgctcgtca aatgaaaaaa cgcaacgctg catacgcagc tgaaaaagaa
     8761 gagaatgcat ctccggcaac ggcgcataat atgacttatg cagccgaagc taaataagct
     8821 aaaaacaccc cgaatgtctt tagacttcgg ggtattattt tacctataaa aaataaatag
     8881 atgtaaaatc catttcaaaa agcatagccc atctcttgcc acacccaata aagaaattat
     8941 caacgtttat gcttttttta actcctttaa gcttgccttt gttggtattc ctcaacgatt
     9001 ctttttgtgt tcttgtttgt tttgtgcttt ttgacttttt gttgtttaat tgcgaattcc
     9061 ttgatttctt ttttcctgaa tcgcttcgca tcccgcggtt atgcgtgcga tttcatcatt
     9121 gctttttctg atctaactcg tttcatgtca aagagcttca gctgacttag tgtccatggt
     9181 tgttttgata tcccttttcc tccttaataa agcggtgatt gatactgcta ttttttcctt
     9241 cacataaaca taacatccca aaaaaatcga ctatcttttt tcaaatggtg tattcaagta
     9301 ttcggaggaa ttagtaatga tgcaccctaa aaataacata attcgcttaa attcaaggct
     9361 accaaaaaac taccaagttc taattatcta gagtttggca gtttctcatt tacacaacat
     9421 atttttcttc tttttcgatt ttttcatagt gcttttgttc atcatcatcc gttataacta
     9481 ctgttacatc attcagatta taatatactg aaaaatctct tttcccaatt ttcgaatgat
     9541 caatcaataa aaagcgttca acagaattat tcagagcgat ctgttgagtt tggccctctt
     9601 caaaagtcga agtcataatt ttctgttcat ttaaagcatt acagctgaaa aatgctttat
     9661 gaaaattcat atcctgtagc gatttattcg tgatttcacc aacaaagcat tgagtcgttt
     9721 cccgcatctc gccacctaat agatagattt ttcgattccc ttttcgctta tttaattctt
     9781 caaaaacagg caaacagttt gtaacaatcc gcagtgaatc cccttgaatg atttttgaca
     9841 tgagctcgat tgtagttcct ggtccaagaa atatcgtatc accatcattg atcatttcat
     9901 tcgccttttc cacaatccgc tgcttttctt cttgcagcat aatctgtttt tctctatgag
     9961 aaagctccac atgccgataa aaatccttca atttcgctcc gccatggacg cgttctaata
    10021 atccttgttt ctccatttcg tccaaatcac gtcggactgt catatccgaa accgaaaact
    10081 tctccataat atcgctgact cgtactgtac cgttaacctc taataacgac atgatcgctt
    10141 ggaatcgatc cgtttttaac atttcatcgc ctcttttctt tttaagacta tcaaattctt
    10201 aagaaaagtg ctagaacaag ttttcttaag aagccttctg caggaaggaa agcaaaattt
    10261 ttcagaattt gcaagctgct attctaaaaa ataaaaccga acgagcatga ctgtcatagt
    10321 gacagccttg ttcattcgac ttttatcttt aataaatcat tttatttaat ctgaagttat
    10381 tgtgcaagtt caaaaacaaa gtagttaatg tctcctcgat atttcgaaat cgaatactca
    10441 acgggcagac gttctagcga aaaaccctgt gtatggaaat agaacattgg atctccttct
    10501 tccacatcta acaaatcgct gatcgtatca tccgctttga ttacttctag ttttctggtg
    10561 accgttttaa ttggataacc catttcttca aaaacttgat acattttttc ttttctgatt
    10621 tgtcaaatta agctagacaa tatgtcttta tctatgcagc tcaaaaatac ttccaatggt
    10681 gttcgataat ttaatgattt tcttggaata tggtttcttt tcgaggcaac ggattgaata
    10741 aaggtttcat ccatgtccct aaagtccatt gttttaggta agccatctcg tctaagcaag
    10801 ccgtttgagt gctcgtgctc atttagccct ctttgcgaag gtgttcctgg atctgcgaaa
    10861 aagatggcaa tatcgttcga gttacttata gatcgccagt tggaaaattc ttttccacaa
    10921 tcaaatgtca tggatttaaa caagtgttta ggcatggatt tgaaccaatc atttaacctg
    10981 ttttcgatat cttcggctcg tctgcctgtc ggtttcaaag taataataac cttggataaa
    11041 cactcaacca atgtaataac agcgctcttg tgtttaactc ccacaatggt gtcgccttcg
    11101 agatgaccaa attctttagt caggtgtgga tagagactgt tccgttcatg aatcgttctg
    11161 cgaaaggcct gttttccacg cttttcttga tgattattcg gtttacgttt ccccttcata
    11221 ggtaacgact gtgtgtcaaa aaggcctttt ttaaacatcc gatagagtgt acgaacagaa
    11281 caatcaattg gaaactcgcc acggccgata atcacatcgg gtgaccaccc ttgagctacc
    11341 ttttcttgaa catatgttga ttgttcatca gataaaacgg ttgaacgtcg tccacaacga
    11401 gatttatttt gtttgtattg acggtaataa tctagcactt ttttccttgt ttgagaaacg
    11461 aataaacatt ataaatggtt tgtctagagc gatttaaact ttgtgcgaca agagcgacag
    11521 gtttctcgat attgaaataa gactctatga ttactagttc gtctgttgta agatgggtgt
    11581 aggtcatttg tactcactcc ttattaattc tttggtcgga actattttga gtgtagcaca
    11641 aatgatcttt ttagttgtct agcttaattt tacaatcgac gcctcaaaaa gaatacccga
    11701 aatttaaaca gcaaaaaaag atagcgctta ccattgtgtt taagataaaa cgctagctaa
    11761 gttggctagc gctttattaa tctaagcaag ctctaaaatt gcttcaatac aaaatcaact
    11821 gctcctttag gatcacgtgt taaattgata tattctgcac ctttagttgc aattactttt
    11881 atccctaatt tgtctgcatc tttacggaga tcatccaaat aggaattcac ttgaggtgct
    11941 agaacgatta aatcaaaatt tttcatcata tcataatgag aaccataagc tcctgcttta
    12001 gcagaaagat taacacctgt ctcttttgcg ccctcttcta atgcattagc caacattgca
    12061 ctcgttccgg caccagcaca aagtactaaa acgcgctttc cttcaccaac cgatgctttt
    12121 gcttcatcaa ctataactgc cgcagttgca ccaacttctt ggatttcttc gaccaattct
    12181 tcttttactt cttctgcagc aatgtttttt aactcttgtt ctactaattc agaatcatag
    12241 gccttaacaa aaggtaaata aataatcgca tcgacaacaa tcaatactac cgctaataca
    12301 atcgccaaca cactaaaccc ggttcctaaa accaagccaa tcggtgcggg cgtcgcccaa
    12361 ggcaatacgg atataaagct attcatcccc aagacatcga caaaaagttt gaatatccat
    12421 acgttagcga ttggtgctaa taaaaatgga attagaaagt acggattcaa aataatagga
    12481 gtagcaaata gtaacggttc atttaccgca aacgaaactg gaataaatga agctttacca
    12541 actgctttca attgttttga tttagcgaac aacatgaaca gaaaaggaac aactagtgtc
    12601 gctccagtac cacccatcgt tccaacaaag tttcctagac caactgttaa tacttttgag
    12661 gcttgtgcac cgtttttaaa taattcaaag ttagtttcta cgttcgcata aataattgca
    12721 gcaatcgctg gttcaacaat cgatggtcca tgaacaccaa caaaccagaa cattgccatg
    12781 gctccccaaa tgattgcaat accgacatat ccatcagcag cactaaataa tggctgcaat
    12841 aattgaatta cacctgctgc aaatgatgtt ccaaaaaatt gacgaactcc cgtatcaatc
    12901 aaaacggcaa taaatactgc aattgaaaag gggataatat ctctaaacat ctgtgtgatt
    12961 gttccgggaa cttcttttgg catacggatc gtcaaatctc ttttaacaca gaatttatac
    13021 acatttacag taacaaacgc agaaacgaaa gctgctaata atccctttgt ccctaaataa
    13081 tcagtagcta tcccaccatc aatttgatca gctgccatca ttacaaaacc acaaattgac
    13141 gctaacataa cagaaacttc attaatctgc ttacctgaat cagataattg acggttcatt
    13201 gaattagcta aacatcgagc tgttgtagca acaaccaaaa gaccaactaa tcccattgaa
    13261 taaccataaa ctttccaaag ccacgtcgag aatgcctctg gtaacgtcac gttaaatact
    13321 tctggaacag ccgcaatcat aataaaaata cttgaaaata gaatagctgg catagcagtt
    13381 aaaaagccat cgcgaattgc ccctaaataa atattacgtg agattttttc aaaaaacggt
    13441 tttcccttct caatttgctt aataatcgta ttcatttttc ttctcctatg ctttagcaaa
    13501 tttttctttg tacaattcaa caaaatcatt gataagttct cttaatagaa tcgttgtcat
    13561 taaatggtct tgcccatgaa taaaaattac gcctacttcc atttcgttcc ctgacgcttc
    13621 ttcagctaaa catttcgttt gtgagttatg cgctaaggtt aaattttcat cagcatccgc
    13681 taataatcgt tcaacattat caaaattacc ttctctcact tccttcaaca ctgttaataa
    13741 tgaacttctg gcatctcctg cataagcaac aatttcaaat cctaataatt gcaattcttt
    13801 cctatccatt tccttgccct cctaactatt tttatattat cgtttttgtt tcgctaacaa
    13861 atttatacca atatgcagac tctttcggat atcttttttg tgtatcgaaa tctacataga
    13921 atagtccata acgcttagtg tatccattaa cccaagagaa aacatccatt aatgaccaaa
    13981 tgaaataccc ctttacatta actcccattt tgatagcatc ggaaatcgca ttaaaatgct
    14041 ggcgtaaata atcgattcga tcatcatcta gaataatccc atcttcaaaa ttatccttat
    14101 accctagccc gttttcagta atgtatattt tattataatt tggatattcg tcttggattc
    14161 gtacaagtaa atcatataac ccttttggat aaatgatcca atcccaatcg gttttcggaa
    14221 gatcctcacg cacgattctc tcgccaatcc ctttaatgca atagacttgg ctaccttttt
    14281 ctccggtagt gttgtagtga agtgtgcttt ctcctttgta ctctttaacc caatggctac
    14341 catagttatt gataccaaga aaatcatttc gatttgctgc ttttttcatc tctctaaaat
    14401 cattagaatc aatatctgca gattgcccat ttgctgctaa aatctcatta atatgtgcca
    14461 ttgtttcatc tgagtaatac cctaaataag tagcatctaa taagaactta attgataacg
    14521 catcatctaa tttcgcagca tgcttatctt cttctttgtc acttgctgga tattttgtct
    14581 ctagcgagtg aacaacacca atttcccctt tatatccacc atctttaaaa atgtttactg
    14641 tctttgcgtg cgcatacatc atgttgtgta aacaagttac agtcttctct atatcaaatt
    14701 gaacttctgg aggaaacgat ccgatcaaat attgatttga agcaactgga taaatctcat
    14761 taaatgtact ccaataatga acctcagaaa attcatcgaa acagaactgt gcatagttta
    14821 cgaaatgttc aacattttct cgatttaaaa aatctccatt atcaaatagt tctttagggg
    14881 tatcaaaatg atgaagagtt acaaaaggaa taataccatg cttattcaat tcagcaaata
    14941 ccttatgata atattccact cctgtttggt tcacttcccc atagcctttt ggaaaaatac
    15001 ggctccatgc aatagacatc ctaatactat caattttaaa ttttttgcat aattcagcat
    15061 caactggata ttgattataa aaatcactag ctggatcagc agtatagcgt cccttttcta
    15121 caaggaaagt atcccacgct acttgccctt ttccaccttc ttttgtagag ccttctgctt
    15181 gataagctgc cgtagctcct cccataataa agtcttctgg taaagtttta taattcattt
    15241 taatctctcc ttgaaaatta gtttgatcaa tatgccaata atccataaat cacctcagca
    15301 taattttaac atgtataagt aaattttttt acacaacgaa aaaccgacct cgaatatcta
    15361 ttttattgcg atatacaagc acttatatcc cttgatgtaa aataaatata ccattcaaaa
    15421 accgttttgt aaacgttttt ttgtaaaata aatttatctt tttactaatt taatttacac
    15481 gaaacaagaa aacggactga ttcccactaa aatcaatccc acctactaat cattctccaa
    15541 gtggctatcc attatcgatt caatcttctc tgttaatgga ttaggctctc tgctgatatc
    15601 agagtttcgt ttcctgctag aaaaagtaat ttaagttact aaaagagcag tttcgattta
    15661 ctttaacaaa gaaaaggatt attatatccc taggaggatg aacaatggtt actattagag
    15721 atattgcaaa aaaatctggt tactcaacgg ctactatatc aagacttttt aaaggtgatg
    15781 agtcactctc tattacatct gatactaaaa acaaaataat cgttacagcc aaatctttag
    15841 gatatgatct gacaaaaatt aagactactc tgtacaagat tgccattctt ttttggatct
    15901 cagaggaaca gttaaaaaag gatgtctact atcaacatgt caaagatgat ttgaaaaatt
    15961 atagtaaaaa agctaatcta gatttgattt tcatctctaa aaacgatggt gtaaaaagca
    16021 ttcctgacga tattactgga tttatcgcaa taggacaatt gacaaaaaag gaattgtact
    16081 acttaaatca aaaagggtat aagggggtaa tccgaggaat aaacccatta cctgaacact
    16141 tcgatactgt agaacctgat ttccacgaaa tggccagaca agcaattaac tactttatta
    16201 atgaaggttt cacaaaaatt ggatttattg gaggaaattt ctttaaccta gaaacgggta
    16261 aagaagagat tgatagccgt gaatatgcct tccgatatca tttagaaaag agcggactac
    16321 tcaatgaaaa gtatattttc tcccaaggat catttactgt tgacgaaggg tatcaattaa
    16381 ctcttaaaat gaaagctgag ttaaatgaag atatgcccga ggcatgtttc ataccatctg
    16441 acactatagc tgccggcgtt cttcagggct gccatgaatt gggtattaac atccctaaag
    16501 atatggcagt aataagtatt aatgatgacg acatcgcaaa attcgttgca ccaccactta
    16561 caacttttaa gatagatatc gaagagatag ctaaaacctg tgtagattta ttaagtgatc
    16621 aactggtata ttcgcgggac atatcaaaga aaacattaat cggcgcaaaa ttgaccgtta
    16681 ggaaaagttt tatccctaaa gaagaggtgt aaaataagta attgaaactt atctttaaaa
    16741 ctataattgt gtccacatag tagccgagca atcgggttta tgcctattat gttttccata
    16801 aataatttga tggtgatatt ttgacgtaaa tacaatatga ttttttcatc gccaaattgt
    16861 gcgcgctaat ttttgtttat cattcagaac atttcctcct ttttatctaa gtatgaggtt
    16921 ggataaacgc ttcatcttag tatcttgggg gattttttat ctcgttggga atatatcaag
    16981 catcagagcg cgcaaaaaga actggtcgaa aaatcaatct accagttcaa tctcattcac
    17041 tgtgatacta tgttttatac agataacgcc atattataaa acaagttgta ttccgcaaat
    17101 gggttctatt caactcttaa actatctata aaagattcag ccaactccat tagcctctcg
    17161 taatttagtt ggtgaacagc acttttttca aaaaattttg aaccaattcc tacataagag
    17221 gctccattgt tcaaatagtt ttgtgggttc tgttgcgaag tttgaaaatc aaacgcgccc
    17281 tctctgaact ccaaatatct taggctgtta
//
LOCUS       DAFLWQ010000061        17185 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.062, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000061 DAFLWQ010000000
VERSION     DAFLWQ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17185
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.062"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(98..1078)
                     /locus_tag="L1V16_002001"
     CDS             complement(98..1078)
                     /locus_tag="L1V16_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1276334.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(1102..2586)
                     /gene="galT"
                     /locus_tag="L1V16_002002"
     CDS             complement(1102..2586)
                     /gene="galT"
                     /locus_tag="L1V16_002002"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HBN1276335.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(2598..3587)
                     /gene="galE"
                     /locus_tag="L1V16_002003"
     CDS             complement(2598..3587)
                     /gene="galE"
                     /locus_tag="L1V16_002003"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBN1276336.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            3835..4002
                     /locus_tag="L1V16_002004"
     CDS             3835..4002
                     /locus_tag="L1V16_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HBN1276337.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(4064..5875)
                     /locus_tag="L1V16_002005"
     CDS             complement(4064..5875)
                     /locus_tag="L1V16_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HBN1276338.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(5872..6237)
                     /locus_tag="L1V16_002006"
     CDS             complement(5872..6237)
                     /locus_tag="L1V16_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HBN1276339.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(6400..6795)
                     /locus_tag="L1V16_002007"
     CDS             complement(6400..6795)
                     /locus_tag="L1V16_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBN1276340.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(6813..7775)
                     /locus_tag="L1V16_002008"
     CDS             complement(6813..7775)
                     /locus_tag="L1V16_002008"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HBN1276341.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(7775..7987)
                     /locus_tag="L1V16_002009"
     CDS             complement(7775..7987)
                     /locus_tag="L1V16_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HBN1276342.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(8008..8706)
                     /locus_tag="L1V16_002010"
     CDS             complement(8008..8706)
                     /locus_tag="L1V16_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBN1276343.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(8726..9268)
                     /locus_tag="L1V16_002011"
     CDS             complement(8726..9268)
                     /locus_tag="L1V16_002011"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBN1276344.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(9400..10404)
                     /locus_tag="L1V16_002012"
     CDS             complement(9400..10404)
                     /locus_tag="L1V16_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBN1276345.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(10401..11390)
                     /locus_tag="L1V16_002013"
     CDS             complement(10401..11390)
                     /locus_tag="L1V16_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBN1276346.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(11387..12193)
                     /locus_tag="L1V16_002014"
     CDS             complement(11387..12193)
                     /locus_tag="L1V16_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1276347.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            12359..13315
                     /locus_tag="L1V16_002015"
     CDS             12359..13315
                     /locus_tag="L1V16_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1276348.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(13392..13910)
                     /locus_tag="L1V16_002016"
     CDS             complement(13392..13910)
                     /locus_tag="L1V16_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBN1276349.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(13998..14147)
                     /gene="rpmG"
                     /locus_tag="L1V16_002017"
     CDS             complement(13998..14147)
                     /gene="rpmG"
                     /locus_tag="L1V16_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBN1276350.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            14375..14821
                     /locus_tag="L1V16_002018"
     CDS             14375..14821
                     /locus_tag="L1V16_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBN1276351.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(15016..16911)
                     /gene="asnB"
                     /locus_tag="L1V16_002019"
     CDS             complement(15016..16911)
                     /gene="asnB"
                     /locus_tag="L1V16_002019"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBN1276352.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT         5174 a         3655 c         2969 g         5387 t
ORIGIN      
        1 ataatacatg attatctgct ggcgggcaaa ttttgcccct tcctgaaaca caaaaaagct
       61 gcggtatcac tccattttcc cacagctttt ccatctttta tttcgttgat tctcgaataa
      121 tcaactctgt ttccacaata atctttcttg aaaccggtgc tttggaatta cttaattgaa
      181 gaatcgtctc cactgctagc tctcccatcc attcggtata aacttttaca gtagaaagcg
      241 agggcgttac atatttcgct acactgacat cattgaagcc catcacagaa atatcttctg
      301 gtaccactaa acctttttct tgaatcgctt tcagtgcgcc aatcgctaat gcatcattag
      361 ctgcaaaaag cgcatcagga acatgcggat tcgtttttaa atattgcttc actgcttgat
      421 atcctgactc gacagaaaaa tctgcttcga taattggacc ttcgtcgtag cctttttctg
      481 ccaaaacttg ttgaaatgcc ataattctgg gatcttttag ccgctgatgg tttttcttcg
      541 tatattctgt tccagcaagc atagcgatat gttgcgcttt atgggagaca aagtgttcaa
      601 tgactttttg aacacttgac ttaaagtcga caactagaga gtcgattcct tgagaagtgc
      661 cgtcagaatc taccaaaagc aaggcatttt gggatccttt catttctaat aactgagctt
      721 cgtcgaattt tcctagtgcg atcgttccat ctgccggaag atcactaatg gaatcccacg
      781 tttctttcaa taaagtaacg tttgcttctt ctgccttttt ttcgattcct aggcgaatag
      841 ataaataata aagatcttca agctcttccg tatcgtcgta ccactggatc aggcgaagcg
      901 tttgcttagt atttgctgca tttttacgat gtttcgtata atttaagcgt tctgctgctt
      961 caaaaatttt ttgctttgtg gctaagccaa cggaaagatc aggatcatag ttgagaactc
     1021 ttgaaacagt agcaggagaa actcctgcca actgcgcaat gtctttaatt gttgccattt
     1081 gtctctcctc cttttttacg tttataaaat cgcagtaaat cgttcaaacg ctgcctgtcc
     1141 tttttcatct cgcttgaata ctccagcgtc ttccagtaca cgtgcaaaaa cctgacctac
     1201 agatttttgt acgacatcgg tgaccgtatc tttcgtcaaa tcaggatgtt ctttttttaa
     1261 ttgttctgcc cacggacgat gatattcagc catctggttt tcttctccta ataagaaatg
     1321 ctctacttct actagttctg gtttcaaacg aggtggtaaa acagcaagcc ccattacttc
     1381 gatcaaccca atgttctcct ttttgatatg ttggacatct ttatgtggat gaaaaatccc
     1441 atcaggatgt tcttctgaaa cattgttgtc tcgaaggaca aggtccaact caaagtaatt
     1501 gtcccttctt cgtgcaattg gcgtaatcgt atggtgtggt gtaccatctg ctgaaaaagc
     1561 tctgatagat actgtttcat ccgaatatgc tttccatttt tccaatactg agttagctgc
     1621 ttcaataagc aagtttttct ctgttgattg caaacggatc acagacatcg gccatttcac
     1681 gactcctgcg atgacttgcg gataatcttc tagtttgata agtttttcta tcggtgcttt
     1741 tgccatagga aattcatgac gtcctgcctg ataatgatca tgagaaagaa tcgatcctcc
     1801 aacaattggt aagtcagcat tcgaaccaac aaagtaatga ggcaagactt cagtaatccg
     1861 aagcagtcta gcaaatgttt cctttgtgat tttcatcggg cggtgttgtt ctgataaaat
     1921 gatcgaatgt tcattgtaat aagcataagg ggaatattgg aatccccagc tttcaccgtc
     1981 tagattcatt cgaataatcc ggtgattggt gcgggctgga tagttcaagc gacctctata
     2041 tccttcgttt tccatgcaaa gcatgcaggt aggatagtct acttttaccg cctcgcgttc
     2101 tgctgcgatt tgttttggat ctttttctgg cttagataaa ttgattgtga tttccagttc
     2161 accatactcc gactctgccg gaaatttgat gttttttgcg atggctcttg ttttgatgta
     2221 gtcatttttc ttacttaaat taaagaaata ctcagttgct tcctctgggc ttttcgaata
     2281 gtgctgtgca aagaatgcat tgacgactga aggtggcggt gtgagaaaat ccattaattg
     2341 cgcttcaaaa atctcttgtt ctgctggcaa ttctgaaaga acaccatttt ctcttgcctt
     2401 agcgacaagc tgatccaata agtctacaga ttcttcctta actggtctta cttcaatgct
     2461 ttctagagca tcttctccta ccatccctaa aagacgattc tgtaaatata agcggtccat
     2521 ttccatccat ccgccagctt cgatcgcaag tgtggcaaaa tcacaaatcg tttgactgat
     2581 tgacatatct cattccccta ttcttcataa ccatttggat ggctgacatg ccaatcccat
     2641 gctgttttga taatcgcttt gatatctgtg tattcaggtt tccagcccag aatctctctc
     2701 gctttttcac ttgaagcgac taatcggcta ggatctccag ctcttcttgg tgctatttct
     2761 gctggaattt cttttcctgt cacttctcta gctgcttcta gcatttcctt gactgagtat
     2821 cctttgctgc tgcctaaatt gaagaagttg ctttcatttc cttctttcaa gtattccaaa
     2881 gctaaaatat gtgcagcaat caaatcttct acttgaacat aatctctgat acatgttcca
     2941 tctggtgtat cataatcgtc tccataaaca gccaaggctt ttctttgacc aagagctact
     3001 tgtaaaatga ttgggacaag atgcgtttct ggtgtatgat cttctccgat agatgcatct
     3061 gcttttgctc cggctacatt gaagtagcgc aaagcgacat agcgcatgcc atatgcttgg
     3121 tcacaccact tcatcatttt ttccatcatc aatttacttt caccatacgg atttttagga
     3181 ttagctggtg tatcttctgt gattggagac tctttcggct ctccataagt tgctgcagta
     3241 gaagagaata cgattttatt cacgttgaac tcgtgcatga cttcaagtaa gatttgcata
     3301 ccgtatacgt tgttgttgaa atacatcaat ggtttttcga cagattctcc tactaaagag
     3361 cttgcagcaa aatggattac tccttcaatc ggttcctttt caaatacgga acgtagaaat
     3421 tctttatccc ggatgtctcc ttcataaaaa tgagcatctg gatgtactgc ttgtttgtga
     3481 cctgtgagca aattatctac cacagctact tgatacccct tttgaactag ctggtctaca
     3541 gcgtgcgaac cgatataacc ggctccgcct agtactaaaa ttgtcataaa aaacactcct
     3601 ttgattagta aaattgtgtt tgttgattct atataattta aaaaacgaag tttactttta
     3661 tggtgaaaac aaacaaagta aaatttcgta aattcatatg gtaaatttat aataaaacat
     3721 ttagtaaaca ttttcaaggg ttttttgcaa aggtttacaa acaaacgtaa aactagcctt
     3781 tttttctctt ttgttccata atagatataa caaataataa atgaggtgga ttcaatgaaa
     3841 aaatttgtat ctggaatatt agtaggaagt ctggcaacag ccgctgccgt tgctggtttg
     3901 gttgcttctg tgaaaaaaac agtgatcgat ccaattgacg aaaaagaagc aatgatcgaa
     3961 gaaaaccgta aaaaagcaat gcgtaaacgc gtttctcgtt aataattatt taaaaatacg
     4021 catgaagact ttctaaaaaa cagataagtc atcatgcgta tttttatttg tcagtcaata
     4081 taagttgtgc tattttatct gcctgtctca gattccatgg atctgtataa ggtctagcta
     4141 ctgctgcagt tagccaatcc acaccttcaa caggtattcc atagcaataa aagtcagact
     4201 ggatttcccc tgaagcatca atcacgcgat tcgtacctcg ctcaacatct atagcttctg
     4261 aatgataact tcctgtatta tctgaaaatg aaaaagggcg aacaagtttg ttttccttca
     4321 aattttttat gacaggatta cttgaacgag aaaagcttgt ttgtggcaat cgagcttcaa
     4381 tcaaatagcg actgctgatt tctttatctt gtagagaaat aacatagcgg ttgtgctttt
     4441 gctgaatatc aaatggcggt tcgatcaaat gaaaaatacc cgcatctatc agtgctgcta
     4501 attctttcgt ccgaatgatt ggcggaccga tcgttaaaaa gctatttaga tgagtaaacc
     4561 atccccatag tatttctttg tattccttag cagaaaaaac gtgccattca atagcctgcc
     4621 ggattggatc acgccagtct tttaatgcat caaatgttga agcaaatgct cctgtgcaat
     4681 tgcctttttc cgcttctttt atctgccctt caataaatat tcggctagct tctgaaaagg
     4741 gctcattctg ataggcaaga ggagtttcta aatacgacca atcccatcta taagggatta
     4801 gtgctggatg ctttccgaga cactcctctg aagagaggga gagaaaatca tgctcaaaat
     4861 ttttctttgg aatcggcaag tgatattctt cgatgatttt cttgtaataa aacaactcaa
     4921 cgtctttttt cagatagtca aaaaatgttt cgccagtcaa aaatcccgac tgatgccatt
     4981 gctccaggtt ttcttttgtt agtaaccgtg gccatgccat tgctccgcct tgcttttgat
     5041 ttcttcctcg agggtaataa gggagccccc ttcttgatcc actgtataca atcggttcct
     5101 tgcctgatgg atgatagacc agttttccct tttcgttctc gaagcgccct cctcttgata
     5161 ctgtaaacaa tccgacataa tcaaaaaaac ttaagcctag acctcttaaa aagacatttt
     5221 ctttaggcgg tatcttcgaa agatctacat ctgcaggatt agaaggaagc tgatacagta
     5281 aaacattttt ctttgcgtag tctacccaca ctctttcttc ttctgtctca tcattttccc
     5341 agtgaccgct tgctaaaaca agctgatcga tagaatagct ttgctgatct gtctgtaaaa
     5401 gataaccatc ttttcttttg cttacttttt ttactaaaga ataaacaaac tgaatagaag
     5461 ctggaaattc ttcttgcaac tttgagaaaa accagcgttg atagagtccg tataaacatc
     5521 gagtagattg ctgatctttt tccagacgat tgatttcttc tataattagt tgcttatttt
     5581 tggttaccgt ctgttcgata taatctgtag caggtccttt actccattga aacaagttgg
     5641 gtccctgtgt taccaatcct ccactggaca atgtttcatc tgtaaaaagc gtcacttgtt
     5701 gagaaacaga attcattaat aactccggtg gctgattcaa ccgccaaact cgacctccag
     5761 gaccattggg atcgaaaaga aaaagttcaa gagaatgtct gtcctgatta ttatggagaa
     5821 tcctttctgc tacacttaat cctctaggtc cggcaccaat gatccctatt ttcatttgca
     5881 tgcctccatt tcgataaatt ttttcaataa aacagcatgg ttctgatgtt cattttttgc
     5941 accataaaca aaagtaatga ctggatgttc tttcataagt tgactgagtt taaaaatagc
     6001 ttgcttcttt tcttcttcga aaatcaattc ttgctggtat ttctttgcaa atgaagcaaa
     6061 tcgttctggt acatggtcaa aagttttgcg tgcttcatta ctaggtgcaa tttctttcaa
     6121 ccacagatct aactgcgctt tttcttttga aattcctcgt ggccagaatc tatccacgag
     6181 tattctatag ccatcctctt tttcagcatc aaggtaaaca cgttttaatt tgatcatagt
     6241 tgtttccttc tttctacctt ttcgcttagc ttatatatgt agataatagc acaaaataaa
     6301 aaaaatgaac ggcacaacta tccattgcgc cgttcatgtg atcttggtca aaatctaatg
     6361 attgattcgg tttttaaagc tgtcatacaa tcatctgttt tatacttttt tacttttgat
     6421 ttttccagac catccgtcat atccaccctt aagtaaataa atctcttgat aacctgcttt
     6481 acgtaattta tttgctgtac ggatgctcaa acttttcttt tgatcgtaaa tatagacagg
     6541 ctggtctttt cgaatagatc ctaatgaatc tttcaaaaca gtgtaaggga tgtttcttgc
     6601 acctaaaata tgcccagcat caaacacatc tttttcgcga acatcgatta cttgtgcttt
     6661 tctcattcct tctcgaaatt cttcttctgt caaagtcgtt gctgaacgtt tggccattac
     6721 tcgtagatag acttcccaaa ggatgattgc aagcacaatc aatagcaaaa tgatattaat
     6781 tacccataaa accatgtaat gcctccgttt ttttaagcaa atttcaaggc taatgaggca
     6841 gcaccaatga caccagcttc attaccaagc tctgctaatt tgatttttgt tgattctctt
     6901 acttgcggga aagtaaattc tttaaaatat ttctctacac ggctacgtaa aaattctcct
     6961 gctgccgata ctcctccacc taacacgata cttgacggat ttaatgtatt ccccaagttt
     7021 ccgcaagcta aacctaagta gaagcatacg cgatcaacaa ccatcaatgc aaacggatcg
     7081 tcttcttgag ccatttcaaa gatatcttta cttgttactt cttctccgtt gtctagcatt
     7141 gctttcagtt ttgaatcccc tgcgtattct tctgccaaga aacgacctag gcgtaccaca
     7201 cctgtagcgc tagatacagt ttctaaacat ccgcgtttac cgcaagtaca ttcgaaccct
     7261 tcaggatcca cagtgatatg tccgatttct cctccagctc cgctcacgcc gtgaatcaaa
     7321 tttccgccag caacgatacc tccgccaaca cctgttccta gagtaacgaa tacaacgtct
     7381 ggatcgtttt ctccagcacc tttccatcgt tcacctaaag cagcaacatt cgcgtcatta
     7441 tcgatagcga atttgattcc tgttcctgcc tcgatcagtt ttttcacaaa ttgaacttct
     7501 gtccagttta agttatacgc accaataacc gttccagctt cgctgtccac gcttcctggg
     7561 gtacccatgc cgattccgat aaagtcttcg gctttcatat tatataaatt caaacgatga
     7621 ttgattgatt caatgatttc aggaacgata tgcttaccat catccaaaat attggtatcg
     7681 atgctccatt tttgctgaat ctctccttct ggtgttaaaa ttgcaaattt tgctgttgtt
     7741 ccacctaaat caatcccaat aatcttcttg tccattacaa atttcctttc tttcggcttt
     7801 cttcaattcg gtgctctctt tttaatatgc gccacgctgt catgtatgta tcatgatcaa
     7861 tcaaacggct atcatacaga ttacgcaatt cgatagtcat taattcaatg tcatagatgc
     7921 gtgcacccac atagataaag atgccaaatt ttttgaacag ctgctgtaca tcatataagc
     7981 tctccatctt taagcacttc cttcatatta tacaagtaaa ccatattttt ttaaacccag
     8041 taaaatacat attacaaaaa gaaatacaaa aactagtgta gaaagaatcc tttggtgtat
     8101 cgaatagctt gtctgttgtt tcggtagacc caaaacattc cctaacacta atccgccaat
     8161 tagcccaccg acatgtcccc aaacatctac agaggtatcc agaagaccaa aaacaaatgt
     8221 caacacaata aataaaagaa aatgtctgac tagctgctgg atcgctgggt tatgtttaaa
     8281 atgaaaccct aagataaaca acgcaccgaa caaaccgaat atcgaagtac ttgcaccacc
     8341 agacagaaca ttcgcttcgt taaaagcaaa gcttgctgta tttcccatta tcccgctgaa
     8401 catataaatc aagaaaaaac gccaatggcc atagattgcc tcgatttgct gccccataaa
     8461 atacagtatc agtgagttca ttacgaaatg catcagtcca aaatggatga agattggtgt
     8521 cactaaacgc caccattcat tgaagtgaac aagataagga ccatacattc cggcataata
     8581 agggatctca agtcgcggaa ataattccat catgaggaag accgctgtct gtatccctaa
     8641 aaaagcatag gtccataacg gtcgtcttaa ccatgcacgc aattttattt gctgttgata
     8701 attcatgaaa acctcccatt tcattttagt caataaacaa ttgttggatc ttctgatcaa
     8761 agctctccgg ttgccattgt tcattcaatt gttcacgaaa aacaaggcta catgtttttt
     8821 tatgaaaatt atttaaatac cggtcgtaat aaccaccgcc aaaaccgatt cgataaccgg
     8881 ctctattgta gataatacct ggtacaatga ggagatcgat catctccggc aaatagagct
     8941 tctctgattg tggctcaaga acaccaaaac tcgaacgtac aagaacggac tgttcatcca
     9001 tttcataaaa cgccatctga cgtttcggca aagttttagg tacaactatt ttcttttgtt
     9061 ctttttctgc tcgttggata accggctgtg tatccagttc aaattcattc gataaagtcg
     9121 tccctatcac ttttgctgac ttccagtact cgctggcgaa tagctgttta tagattcgct
     9181 gttctttttc ctttttcttg ccacttttgg ccagattttt cagcttttcg attcctttcc
     9241 ggcgtaatct tactttcaat tggtccaaaa actcaccctt ccttctctca taaaatggta
     9301 taggaaaaaa agaaaaatag caatcgaact ttcaaataaa tgcataaata gaataaaaag
     9361 aagacctaga aatgattggc cttccttttt taatgaattt caactgttca gcgcgtgttt
     9421 ttgtctgata aaaagtgcat acagaaaata tggcgcacca aaaagggcaa tcaaaattcc
     9481 tgtaggtact tccccacttg gtagaatcac tctagcaacc atatctgcac taagcagaaa
     9541 aatggaaccg aacaaaccgc tcagaacaaa ggtccagtta ttttctttac gtacgactag
     9601 cttcgcagca tgaggagcta gtagtcctac aaaagataaa ctacctgtca ccgctacact
     9661 accgcttgcc aaagcaacag ctaacaacaa aaggattttt tgacttttag ccacgttaag
     9721 gcctaatcct tgcgcgcgtt cttgaccaaa tgatagcaat acaatcctct gtgcataaag
     9781 tcctcctagc ggaattaaga taaccgccca tggaagcaat gcccaaacat aaggccagct
     9841 cgcaccccag attgatcccg ctaaccatgc attcacaaat ccataatttt ccttagataa
     9901 ttggatcgtg catagcaatg ttaatgcaga aaggccggca ttaacggcaa taccggacaa
     9961 taagattcga ttcataccca aaaagccatt tcgatcatag gccgcaagat agacacagca
    10021 agcagctaaa acaccaccta gaaaggctac aactagcaat agaaacggca gcgaatagtg
    10081 cgaaaagaaa cctaaataaa gcatcactaa aaatcctgct ccggcattaa tgcccaatat
    10141 actagaatct gccaattcat ttcttgttac tccttgcaag atataaccag aaacgccaag
    10201 acaagctcct gctaataaac tgatcagtaa tcgaggaact cgaaattctc taacaatcag
    10261 cgccaaagaa gatgattctt tccctatgaa cgtggcaaaa agctgatcca ggtaaataaa
    10321 aggcgtacca atcattaaac tacctataga caggatgaca agtacaaaaa gcaagaaata
    10381 gaacgtccaa tatatttttt tcaccgttgt tccctcctta cttgtatcag taaaaacgga
    10441 acgccaatca atgcaatgac taatccaaaa ggtgtttcaa aagggggatt gatcatcctc
    10501 gctgtaaaat ccgccaacat aaccaatcca ccgccaacta aaaaagagac aggtagaaca
    10561 taacgatagt ccgttccaac cattccgcga acaactggcg gaaccaacag cccaataaat
    10621 gaaacaggtc cgactaacga aacggcaatg gctgctaaca ctgcaactag acagaaaaca
    10681 atcaaccgcg ttcgtttagg atgacttcca agagctaatg catgtgtttc actcaaatga
    10741 atcaaagata ttgcttttcc taatgaaaaa gaaaccaaaa cagcaagtat atataaagga
    10801 aacaatactg ctaattgttt ccatgtgata ttggcagctc cgcctacaaa ccaaaaagca
    10861 agatcctgct gcagattaaa gaattgggta agtgcttggc tgatagcagt aaaaaaagaa
    10921 ctaatagcta cgccagctaa aatcagctgt aaaggattca tgcccatttt cgaaaactgc
    10981 aaaaaaccaa atacgagcaa agttacagca aaagaacctg ccaatgacat tagaaacaca
    11041 gaaaaatcag aagctttagg ccaaaaagca aaactaaggg ccattgccaa cgaagcaccc
    11101 gcgttgattc ctagtaagcc tgaatctgct aaaggatttc ttgtcactcc ttgcatcaat
    11161 gcaccgctca atgcaaaaca actccctaca agaaatgctc ccgccacacg aggcaaacga
    11221 atatttcgta tgatttggtg actttgtttt gatctatcaa aatcaaacaa cgcctgccaa
    11281 aaatctgctt tttccacagt cgctgcgcca tttgaaagag caacaaaaaa aataatcaaa
    11341 agaacaaaac agaccaaaag caggagtcta tttttcttca tagtcctcat aattgatcct
    11401 cctgctcttt tggcaacaaa tcataggtta gaaaaactgg tttatttgtt cttggaagcg
    11461 tgacaatcgt tgcatcaatc tcaaatattt ttttcataca ctcttttgtg atcacttctt
    11521 caggtgtacc ttctgtgatc aacttaccgt ttttcattgc taataaataa tctgaaaaac
    11581 gtgaagcatg attaatgtca tgaatcgaca tcaagatcgt tgtttgtttc atttgattga
    11641 tttcagtcaa taactgtagg atctctaatt ggtgtgccgg atctaaaaat gttgtcggtt
    11701 catccaagat caagatatct gtttcctgag caagcgccat agcgatccag acacgctggg
    11761 tttgtccacc agacagcgtt gcgatatccc gcatacgaaa tccagctaga cctgtagcat
    11821 ccaacgccca ctcaattgct tcatgatctt gcgtgtccat gccactgaac agtttttgat
    11881 aagggtatcg tccgtaagat actacttctt ctactgtcat acctgtaggg tgttcactag
    11941 tttgtgctaa taatgcaatt ttttttgcaa gttcttttga actgtatgta gagatatcag
    12001 agttattgac aatgatcttt cctgatttca caggtagtat acgggtaaaa cttttcaata
    12061 aagtagattt tccacttcca tttggcccaa tcaaactagt gattttccct tcaggaatcg
    12121 taacagacat gttttcaatg atttttttgt tttcgtagcc ggctgcaatg tcagctgctc
    12181 ttaatctcgt catttcaccc atcctttcgc tgaaaatcat tctcaattat gacgctgttt
    12241 caacatttcg tcaagcgcta ctttcatatc tatagccaaa tgaagcggtt gacagcgttc
    12301 gaaatatcag gaataataac caatgagaaa gattctcaat tatgttagga ggaaagaaat
    12361 gaaattaaaa acaaaagtat tcacattatc tagcatattg ctgctggctg gagtactgag
    12421 cgcttgctcc ccctcttcag ataaagaaac agctacaact gccaattcga cgacttcatc
    12481 caatagtact catacagtca cagatacact tggacataaa gtagagattc caaacgcgcc
    12541 caaacggatc atcggcagtt acttagaaga ctatctgatt gcactagggg aaaaacctat
    12601 cgcccagtgg actgttggca gtggttccat tcaagattat ctgcaagatg atttaaagga
    12661 tgtcccaacg atttcttatg accttcctta tgagaaagtg ttaagctttg agcctgattt
    12721 gctgttgatt tcttcttccg ctactgtcga aggcgggaaa tacgaacaat atagcaaaat
    12781 cgcgccaact tatgttgtaa aaaacggaac agatgtcaca tgggaagaac aactaaaaga
    12841 tgtcggcaaa gctttggcaa aagaaaaaga ggcagaaaaa atcatttccg attatcaaaa
    12901 atccatcaag aaaactcgag aagaactagc agataaaatc gagaacaaga cagctgcagt
    12961 gttgtgggtg accaacaact cagcctttat ggtcagcaaa aatcggtcaa gtggaagaat
    13021 cgtatacgac gatctggaat ttggtgttcc tgatctagtg gaagaggtct ccaaaaaagc
    13081 cacttctgac tggtctgctg tttcctctga aaagctagct gaattagatg ctgactacat
    13141 catccttgtg aacagtgaca aagatgctgc catgttcaat gaaccaagct ggaagaatct
    13201 aaaagcagtg acagacaatc atgtactgca attcggacct gaatctagtt ggctatataa
    13261 cggacctatt gccagtcagg aaatggtcaa tgatatcaaa gaaaaactaa attgatttta
    13321 actaaaaaaa gcatcttcac gattagtcgt gagatgcttt ttttcttatt aacaaactag
    13381 acgcatagat tttattcttc ttttgaagca accctatttt ttactctttc ccatttttga
    13441 aaacgatggg catatagatt ttcttgatcc gttatcccct catactcctc tataagggcg
    13501 aagtctgaaa aatcaatatt cccaatatac gtatcgcctt caaacgtgct atcgatcaat
    13561 gttcgccaga tccgaccagt gtaaggaaga agttcttgaa aaatccgact accacccgaa
    13621 acatagatat cttctgagat cgtttgacta tacgacaaaa gttcatcgat cgaatgcatt
    13681 acttccgcat tttctttcgt gcgaaaattt ggttgcgttg tcaacacgat gatatggcga
    13741 taaggaagtg aaagatcccc cattccttca taggtctttc ttcccatcac taaaattcga
    13801 tccattgtat gttcgcgaaa gaaacgcata tcatttggca atcgccatgg taacaaacca
    13861 tttttgccga tcagaccatt tttatcttgt gcccacatgg aaataaacat attatccgct
    13921 ccttatgatt ttagatgttt tgagataaaa aaagtctcaa ttctttgacc agcaaggaat
    13981 tgagaacttt aaaaacatta ttttgtttca cggtgcaaag taactttgcg ttcgcgtggg
    14041 caatattttt gtttttccaa acgatcagga ttgttacgtt tgtttttgct tgttagatag
    14101 ttacgttctt tacaagaagt acactctaaa gtgatgttta cgcgcatgtt tttccctccc
    14161 atttttacaa gaatcctcta agatgactct cagacttgat tatcttacca tgattttttc
    14221 tagattgcta gtgtttttca cgattttgtt aagtaaaact acttgacgat aaatacaacg
    14281 gttttacttc tcaaacaaaa tctttttctt tttgtataaa tacccttaca cttgtttata
    14341 tagattatgt tttttaataa agggggatac taatatgcca tggaacatga aggactttcc
    14401 tgcatcaatg aaaaacttag ataaattgac aagaaaaaaa gcaatcgaca tcgcaaatgc
    14461 attattagat gaagggtacc ctgataaccg tgcgatccca attgccattg atcaagcaaa
    14521 aaaatggtat gaagatgcta gtgaatcaga aaaacgaact ttcgaaaaag aaaaaaatcc
    14581 aagcaagacg gatgaacacg atacgaatcc tcgtgctgga aaactgcttg attcagatgt
    14641 gatcgtagaa tatgaggaag aacaatggat cgtgaaatct aaaggggcaa aaaaggcaag
    14701 caaccatttt gatacaaaaa aagaagcaat cgaaaaagga aagcaagtag cacaaaacaa
    14761 agaatcaact ttgttcattt ataaaaaaga tgggacaaaa gaaaaagaaa tcgattattg
    14821 aacatatgta aaggggttgt gacgaaaatc gtgtcacaac ccccttatgt tcgaaacaat
    14881 ggtgttcctc tgccaactcc gaaccataag tcataatatc tataaaacgg gaagagctgt
    14941 tttttgaaat tgtttcttat cactcagtgt taaacggtag gagaaaacct cttttttatt
    15001 gatatttgat tttcatcaaa cagtcacata gtcgattgct tctgcttgcg gaatcgtttc
    15061 atctacaaag tagactttat accatgtcaa gaaactgaag attgtccaga tttttctttg
    15121 ctcttcttta cgtccttcgt gatggtcatc tagcaacttc atgatttttt cttgatcaaa
    15181 aaattctttt gcaaaatctg cttcgaataa tgctttgact tgttcgtagc cgtgttcttc
    15241 tttcaaccaa gctttgattg gcacagggaa tcctaatttc acacgattcg accattcttc
    15301 cggaagatgt ttgttcgcag cttgtctgaa aatatctttt gtgttgtttt gattcaataa
    15361 aaacttactt ggtatttgtt gagccaattt catgacttcg atatccaata aaggtactcg
    15421 gacttccaaa gaacttgcca tagaaagttt atctgccttt aacaagatat cttttggcat
    15481 ccattgatga agatcgacat attgcatctt attgacttca tctttgattc cttctgtttt
    15541 ctcgtaatga acagtcatga tttcatccac agatggtgct gtttgatatt ttggtgttaa
    15601 cacttctgat gcttctgatt cttcgaacac tcgagcatga ccgataaaat attcttttgc
    15661 aggagcaagt gattcatata aatggatccg tccatggaag tttttcattt ttccgatttt
    15721 acgtcctaaa ttatagcgtg ttccttttgg taattttttc aatccttgag caatcacacg
    15781 gatgaatttt gaattcgtat ggaatccata cgtttggtat cccgcaaaca gttcatccgc
    15841 cccttctcca gattggacta cccgcacact ttgtgaagca agatttgcta aaaagtacaa
    15901 aggtacgcaa gaaggatttg aatcaggttc atctaagtga tactggatca aagggaatgc
    15961 tttgaacgac atgtctccgt cgatcactgc tgctgtatta tctaagtcca atagttcggt
    16021 tagttttctg gcttcaatcg cttcattata ggttttatca tcaaacccga ttgagaaaga
    16081 atgatctggt ttcaatacag aggttacata actggaatca accccgctgg ataagaaaga
    16141 accaacttct acatcactga ccgtatgtgc ttcaatagaa gcttgaacgg tttcgtcgat
    16201 tttttcgatc cattcttgtc gggaatgcgt ttcttttgtt tcaaaatctg catcccaata
    16261 ttgctgaatg tctatttttc catctttata cgtataataa tggccttcag gcaaacgata
    16321 gacatctttg aagaatgttt cgccgtttaa tggagaatat tggaaagtca tataaggttt
    16381 caacgcttct ttgttcaatt ctttgttaaa atcaggatga ggcagaaaac ttttgatttc
    16441 tgaaccaaac ataaatgttc cgttcatttc tgcataataa tatggtttga tcccaaagtg
    16501 gtctcttgca ccgaataact cattcttttc attatcccaa atagcaaaag caaacattcc
    16561 gcggatcttt tgcaataatt ctgttcccca ttcttcgtaa ccatgcaaaa ggacttctgt
    16621 atctgcatgt gtttgaaaaa cgtggccagc tgcaatcaat tcttctctca aaggctggta
    16681 attatagatt tcgccattaa aaataatgat ctttgtccga tcttcattgt aaataggctg
    16741 agtaccgccc tctaagtcaa taatacttaa tcttctgaat cctaaagcaa catgtttatc
    16801 gatatattct cctgaactat taggtccacg gtgaacgatt cgatccatca ttgtattaat
    16861 aattgttttt ttgttgtcct tgtcgttaac aaaacctaca ataccgcaca tttaactttc
    16921 acatcctaat ataaaattac tgtttatttc attcatatgc atcttatcat agaataaata
    16981 gcggacgaat attttctctc ttacaatttc gtcacgtgaa aacaaaagat gaaagtttct
    17041 gtttttacag aaaataaagt cccaatatct aatttaccat gttttctttt ttgaggctac
    17101 cttattctct tcgtgttaaa aaaatattag tggatgctat ttccaaaaaa accagcaaaa
    17161 aaagacacga cctaaagatc gtgtc
//
LOCUS       DAFLWQ010000062        17089 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.063, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000062 DAFLWQ010000000
VERSION     DAFLWQ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17089
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.063"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(33..1076)
                     /locus_tag="L1V16_002020"
     CDS             complement(33..1076)
                     /locus_tag="L1V16_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1276353.1"
                     /translation="MKKILVSLLFLVSLVTLVGCSQSQGEKQSEKEKSKIALVLGFGG
                     VDDRSFNQAGWEGLEAWGKEKKLTAKKDFTYIETNNPEDNSTNIDQAIRNGFTTIISL
                     SYLQAEELENAAKDNPKLKFALVDGEITGKKNISSATFKDQESAYLAGLAAAYTTKSD
                     QVGFIGGMEGPVIQRFQSGFEAGVKAGATALNKEITVNVQYAASYDSLDKGKAIAASM
                     YKEGVDILYQAAGSTGAGVFQEAKARNENDYSRKVWVIGVDRDQADEGDYKMENGETG
                     NFTLTSTKKNVGAEVKEFAETSHNDKFPGGKHLTFGLKEEGVDLTKGQLSEEAYQAVS
                     DAKEKIISGDFRL"
     gene            complement(1237..1920)
                     /locus_tag="L1V16_002021"
     CDS             complement(1237..1920)
                     /locus_tag="L1V16_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HBN1276354.1"
                     /translation="MKKIHDTKQLTAYVEKHNLQDYMDSDILAMASLLFFEKEEHLIQ
                     TGKTSDYLYFLVDGTVMVYSYSSDTQNICIDYAKPATPLGEASSLWELSPKSSVKAVT
                     KCICISIPLNQYRTQLQKDVRFLQNICQLLSYRLNSGINLANSLTEPVETRLAKFILT
                     HHENERFSFRLTTCASILNVSYRHLLRTITNFREENIIEKKKNYYLIHDIEALEDLAE
                     NISSPVKAE"
     gene            2115..3044
                     /locus_tag="L1V16_002022"
     CDS             2115..3044
                     /locus_tag="L1V16_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBN1276355.1"
                     /translation="MQFKQLAKGFIGVMLLTTLAACGSGNTSSSSEKESKEKLVVQFV
                     PTNNDGSMEAKAKPFAKYLSKKLDREVEVTLATDYSTIVEAMSSGQVDVGIMPPAAYV
                     QAKDAGAADAILTSQLGDYDQETGLPLKDKLTNTFKGEVLVRADSGLNKLTDLKGKNI
                     ATLSPNSASGYIYPVAELKDAGIDPTADTKMTTVNDIPSEITAVLNKQMDAAFVFEGA
                     RNVFASNFPDNDLFKDLKVLYLTKGDIPNDAIAVQPDMSKDLKAKIKETFLNMKDDKD
                     GKEAMALWGHQGYEEAADSAYDTIRDYTKKAAE"
     gene            3105..3896
                     /gene="phnC"
                     /locus_tag="L1V16_002023"
     CDS             3105..3896
                     /gene="phnC"
                     /locus_tag="L1V16_002023"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HBN1276356.1"
                     /translation="MIIFDNVSKVYPNGVVGLKDIDLTIEDGEFVSIIGLSGAGKSTL
                     LRSINRLAETTKGDIRINGTSITKANKKELRQIRRQIGLISQSFNLVKRSTVQKNVLS
                     GRLGYYSTWKSILGLFTKEDYQQTKEALEKVGLSDKLQTRSDELSGGQQQRVSIARAL
                     VQQAPIILADEPVASLDPITTQKVMMDLKNINQTMDKTVIVNLHSVPLAREFSTRVLA
                     LKAAQVVFDGRPDDLTDERLEQIYGNAIFEEKAGEIDELERNRSL"
     gene            3868..4647
                     /gene="phnE"
                     /locus_tag="L1V16_002024"
     CDS             3868..4647
                     /gene="phnE"
                     /locus_tag="L1V16_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HBN1276357.1"
                     /translation="MSLKETVHFKWYKHLLILLFLIVCFQGSAWITSADFSQVFQNSN
                     QMTVFLSRFIHPDFSYLPKLVEPMVKTLQMSLLGTVIGLILAIPVSFLATTVVTENRL
                     LSTIFRFLLGLVRTIPTLLLAALFVAVFGIGEATGVLTIAVFTFGMVSQLMFQAIETI
                     DFGPIEAAAAVGANKMQIAIWSIAPQVLSQFASYAFYAFEVNVRASTVLGYVGAGGIG
                     VILNSSLALLNYERVSIIILTILVTVAIVDKLSERVRRSLL"
     gene            4644..5426
                     /gene="phnE"
                     /locus_tag="L1V16_002025"
     CDS             4644..5426
                     /gene="phnE"
                     /locus_tag="L1V16_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005233297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HBN1276358.1"
                     /translation="MMLREMNRRTLLSLVALVILVILSAATLDYSGLSTFSPSMGMDV
                     LRGLGQPDWQFLYDGSGEDLISLLLLTIGIACLGTMIATVLAIPITLISAVNLWQAHP
                     WVTKIGKLICNVLRAFPELVFAIIFVKVVGPGPFAGVMAIGVHQIGMLGKLFTEEMEA
                     MDERLVEEMHAVGANFWQTIFFVRIPYLMPIYCSLALNHFEIAVRSAATLGLVGAGGI
                     GAPLIFAIQTRSWSKVSIILIGVVVTVFILDQITGIIRKRLR"
     gene            5429..6232
                     /locus_tag="L1V16_002026"
     CDS             5429..6232
                     /locus_tag="L1V16_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBN1276359.1"
                     /translation="MNILHISDIHFRREYEACEEGYKGMLATMQNPLIPLEQCIHHLL
                     QQTPLDLVIISGDLTEDGEIDDYRYLKTWLENALGETTILVTLGNHDIKEHFWVGWCD
                     EAASSAPYNQIVKYPEFTVISFDNSSYGYADGIVDDQQFQWLKKALEQEKDQPIFLVT
                     HHHLLSHQSSIPKWPGTERFLKLIAPYDIRCILNGHTHHTFTDEINGIPYFTVSSMSF
                     VGEDEGDGFVRFEERHGYNLYHLDQGRIVRQTTENFIPGNILKTLQMKD"
     gene            6316..7863
                     /locus_tag="L1V16_002027"
     CDS             6316..7863
                     /locus_tag="L1V16_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HBN1276360.1"
                     /translation="MNITFLETSDMHGYVSPTDYSGRTDLALGTAKVSSKLKELRAKA
                     DGPVITIENGDFIQGSPLSYYLAKEYGSAKELTDLINQMSYDVQVLGNHEFNYGVDYL
                     EEAIKNYQAPILGANMVNKNDQPYFGNAYKIIEKVGVKIAILGLTTQYIPHWEKPETL
                     AGITFKSIVETAKEYVPLLRKQADLVIVSYHGGFEKDLLTGEDTEALTGENEGYELLQ
                     QVEGIDALFTGHQHRKIAETVHGVPVVQPGYRGEFIGEIRLTVEKKEGQVVVTDHQVA
                     LHSVEKSEPDPEILAAIVPVEEKLEKWLDQPLGKVNGNMRINDPMQARLEEHPYVEFI
                     NRVQLFASGSEISGTALFNNEGKGFGETITMRDVITNYIYPNTLAVIQINGADLRAAL
                     EQTANYLAVENNQIVFNPAFIQPKPQYYNYDMYEGIQYTIDMKQPVGQRITELRFKGH
                     PVLPQQMLEVVTNQYRAIGGGNYAMFGAEKIVREIQIDMTELIADYLNIHPRIEAKVN
                     HNFQVIL"
     gene            complement(8160..8357)
                     /locus_tag="L1V16_002028"
     CDS             complement(8160..8357)
                     /locus_tag="L1V16_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276361.1"
                     /translation="MVECLKNKKMEANFVKAVISGSIVFQEEYRDMEKDFSKKGIELI
                     DYPRSCPILDKEYPEILTTFF"
     gene            complement(8433..8633)
                     /locus_tag="L1V16_002029"
     CDS             complement(8433..8633)
                     /locus_tag="L1V16_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBN1276362.1"
                     /translation="MIEEEQKNIWDRYYKADPSSKNTKIGESGLGLSIVKELVRLHHG
                     SIEVTSRKNEGTTFLIQFPKEK"
     gene            complement(8753..9940)
                     /locus_tag="L1V16_002030"
                     /pseudo
     CDS             complement(8753..9940)
                     /locus_tag="L1V16_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9985..11111)
                     /locus_tag="L1V16_002031"
     CDS             complement(join(9985..10883,10883..11111))
                     /locus_tag="L1V16_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBN1276363.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIISKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            complement(11515..12297)
                     /locus_tag="L1V16_002032"
     CDS             complement(11515..12297)
                     /locus_tag="L1V16_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276364.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(12362..13198)
                     /locus_tag="L1V16_002033"
     CDS             complement(12362..13198)
                     /locus_tag="L1V16_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1276365.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(13216..14625)
                     /locus_tag="L1V16_002034"
     CDS             complement(13216..14625)
                     /locus_tag="L1V16_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1276366.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(14639..16462)
                     /locus_tag="L1V16_002035"
     CDS             complement(14639..16462)
                     /locus_tag="L1V16_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1276367.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
BASE COUNT         5066 a         3468 c         3194 g         5361 t
ORIGIN      
        1 actgtagaca tcatccataa aatggacttt gtctacagtc tgaaatcacc actgatgatt
       61 ttctcttttg cgtctgaaac tgcctgatag gcttcctctg ataattgtcc ttttgtcaga
      121 tctacccctt cttctttcaa accaaaggtc aaatgcttgc cgccaggaaa tttatcgtta
      181 tgagaagttt ctgcaaattc tttgacttct gcaccgacat ttttctttgt agaagtcaac
      241 gtgaaattcc ctgtctcgcc gttctccatt ttataatccc cttcatccgc ttgatcgcga
      301 tctacaccaa tcacccatac ttttctgcta tagtcgtttt cattgcgggc ttttgcttct
      361 tggaacaccc cagctccagt acttcctgcc gcctgataaa gaatatcgac tccctctttg
      421 tacatagaag cagcaatagc ttttccttta tctagcgaat cataggatgc agcatattgt
      481 acgttaacag taatttcctt gttcagtgct gtggcccctg ccttaacgcc agcttcaaat
      541 ccgctttgga aacgttggat cacgggccct tccattccac caataaagcc tacttgatca
      601 ctttttgtcg tatatgcggc agctagtcct gctaaatacg cactttcttg atctttaaag
      661 gttgctgatg agatattctt tttcccagta atctcaccat ctaccaaggc aaatttcaac
      721 tttggattat ctttagcagc attttccagt tcctctgctt gcaagtagct caagctaata
      781 atggtggtaa agccgtttct gattgcctga tcgatattgg tactgttatc ctctggattg
      841 ttcgtttcta tatacgtaaa atcttttttt gctgtcagct ttttctcttt tccccaagcc
      901 tctaatcctt cccagccagc ttgattgaag gagcggtcat caaccccgcc aaatccaaga
      961 accaaagcga ttttactttt ctctttttca ctttgcttct ccccctgaga ctgactacag
     1021 ccgactaacg ttactaatga caccaaaaac aacaatgaaa caagtatttt cttcaaaatt
     1081 tttctcccct ttttatgtgt cttgacacat tgaactttta aaagtatagc ataccaatat
     1141 atagaacact actcttcaac gaagattttc cgtttcccaa tttctccact atcaaaaaac
     1201 cagcaatcac ttctgactgc tgttttttta tagctgttat tctgctttta ctggactact
     1261 tatattctca gctaagtcct ctaaagcttc gatatcatga atcaagtaat aattcttttt
     1321 cttttcgata atattctcct cacgaaaatt cgtgattgtt cgtaaaagat gtcgataact
     1381 gacatttaag attgaggcgc aggtggttaa ccgaaatgag aaacgttcgt tttcgtgatg
     1441 ggtcaaaata aactttgcta aacgagtttc aacaggttct gtcagtgagt tcgccaaatt
     1501 tatcccggaa tttaaacgat aacttagtaa ctggcaaata ttctgcaaaa agcgaacatc
     1561 tttttgaagc tgtgttcgat attgatttag cggaatgctg atacagatgc acttagtcac
     1621 tgctttaacg ctgcttttcg gcgataattc ccacaatgaa gaggcttcgc cgagtggtgt
     1681 agcgggcttt gcgtaatcga tgcaaatatt ttgtgtatca gaagaatacg agtacaccat
     1741 taccgtccca tccactaaaa aatacaaata atctgaggtt tttcccgttt gaatgaggtg
     1801 ctcttccttt tcaaaaaaaa gtaaagaagc cattgccaat atatctgaat ccatataatc
     1861 ctgcaggttg tgcttctcaa cgtaagcagt taattgcttc gtatcatgga tttttttcat
     1921 gaaatcgtca cctctaagaa gtttttcttt attatagctt agattgtttt tcggctcaat
     1981 acgaataatt atttataatt gtttgtaaat tgtatgtaaa agttgtgtaa aataggacgt
     2041 gcgtcacttc attgattttg attccctgct atgatttaga cgtattagaa attatatcca
     2101 acaggaggag aaaaatgcag ttcaaacagt tagcaaaagg gttcatcgga gtcatgttat
     2161 tgaccacttt ggcggcctgc ggttctggga atacaagtag cagctcagaa aaagagagca
     2221 aagaaaaatt agttgttcaa ttcgttccaa caaacaatga tggtagtatg gaggcaaaag
     2281 caaaaccatt tgctaagtat ttatcgaaaa agttagatcg tgaggtagaa gtgacgttag
     2341 ctactgatta ttcaacgatc gtcgaagcga tgtcttctgg tcaagtcgat gtcggaatta
     2401 tgccgcctgc agcctatgtt caagcaaagg atgctggagc tgcagatgca atcctgactt
     2461 ctcagctcgg cgattatgat caagaaactg gcttgccatt aaaggacaaa cttacgaaca
     2521 cctttaaagg agaagtattg gttcgtgccg atagcggatt gaataagtta actgatttaa
     2581 aaggaaaaaa tatcgcaacc ttaagtccta actctgctag cggctacatc tatcctgtcg
     2641 ctgaattgaa agatgctggg attgatccta ctgcagatac aaagatgacc actgtgaatg
     2701 atattccgag tgagattacc gcagtgttga acaagcaaat ggatgcggcg tttgtttttg
     2761 aaggcgcgcg aaatgttttt gcttcgaatt tcccagataa tgatttattt aaggatttaa
     2821 aagtcctgta cctgacaaaa ggcgatattc cgaatgacgc aatcgctgta cagcctgaca
     2881 tgtcaaaaga tttaaaagcg aaaattaaag agaccttctt aaatatgaag gatgataaag
     2941 atggcaaaga agcaatggct ttgtgggggc atcagggcta tgaagaagct gctgattctg
     3001 cctatgacac gatcagagac tacacgaaaa aagcagcaga ataaaacatc agtaagtgtc
     3061 agcaagcttt tttttgctta cacttaaaaa aatggagaag gataatgatt atttttgaca
     3121 atgtttcgaa ggtctatccc aatggcgttg ttggcttgaa ggatattgac ttaacaattg
     3181 aagatggaga atttgtttcc atcatagggt tgagtggtgc tggaaagagc actctgctgc
     3241 gcagtatcaa tcgcttggca gaaaccacca aaggagatat tcgcattaat ggaacctcta
     3301 ttacaaaagc gaataaaaaa gagctgcgac agattcgccg ccagattggt ctaatctcgc
     3361 aaagcttcaa tctggtaaag cgtagtacgg ttcagaaaaa tgtgctatct ggacgtttgg
     3421 gctattactc cacttggaaa agtattttag gtctttttac gaaggaagac taccagcaga
     3481 caaaggaagc actggaaaaa gttggtttgt ctgataaatt gcagacacgc agtgatgagc
     3541 tcagtggtgg gcaacaacag cgagtatcca ttgcgcgagc actcgtgcag caagccccca
     3601 ttattttagc ggatgaaccc gttgcatcat tagatccaat cacgactcaa aaggttatga
     3661 tggacctaaa aaatatcaat caaacgatgg ataaaacagt cattgtcaat ctgcattcag
     3721 tccctctggc tcgtgagttt tctacgcgtg tgctcgcgtt aaaagctgct caggttgtct
     3781 ttgatggtcg tccagacgac ttaaccgatg aacgcttaga gcaaatttat ggcaatgcaa
     3841 tctttgaaga aaaggcaggc gaaatcgatg agcttgaaag aaaccgttca ctttaaatgg
     3901 tataaacacc tgcttattct tctgttctta attgtttgtt ttcaaggaag tgcctggatc
     3961 acgtcagctg atttttctca ggtttttcaa aactccaatc aaatgactgt ctttttatca
     4021 cgcttcattc atccagactt tagctattta cctaaattag tcgagcctat ggtgaaaaca
     4081 cttcaaatgt ctttgcttgg aacggtcatt ggcttaattt tagcgatccc tgttagtttt
     4141 ttagcgacca ctgtagtgac agaaaaccgt cttctttcta ccatctttcg ttttctttta
     4201 ggtttagtac ggaccatccc taccctgctt ttagccgcgc tttttgttgc tgtgtttgga
     4261 attggtgaag cgactggcgt gttgactatc gctgtcttta cttttggtat ggtgtcacaa
     4321 ttaatgtttc aagcaattga aaccattgac tttggcccga ttgaagccgc tgcggctgtt
     4381 ggagcaaata aaatgcaaat cgctatttgg tcgatcgctc cacaagtttt gagtcagttt
     4441 gcgagctatg ctttttacgc gtttgaggtg aatgttcgtg cttctactgt ccttggatat
     4501 gtcggagctg gtggtattgg cgttattcta aattcctcac ttgcgctttt gaattatgaa
     4561 cgagtttcaa tcattattct aacgatccta gtaactgtcg cgatcgttga taaattaagt
     4621 gaacgtgtca ggaggtccct gttatgatgc ttcgtgaaat gaacagaaga acccttttat
     4681 cattagttgc tttagtgatt ctcgttattt tgtcggccgc tactctggat tactctggat
     4741 taagcacctt ctctccttcc atgggaatgg acgttttgag agggttaggt cagcctgatt
     4801 ggcagtttct atatgatggc agcggcgagg atttgattag tttgctatta ttaaccattg
     4861 gaatcgcctg tttagggaca atgatcgcta cggtattagc gattcccatt accttgatca
     4921 gtgcggttaa cctctggcaa gcacatccat gggtaacaaa aattggcaag cttatctgta
     4981 atgttttacg agcttttcct gaactagttt ttgcaattat ttttgtgaaa gtcgtcggac
     5041 ctggcccctt tgctggtgtt atggcgattg gcgtccatca gatcggaatg cttggcaaac
     5101 tttttacaga agaaatggaa gcgatggatg agcgacttgt tgaagaaatg catgcggtag
     5161 gagcaaattt ttggcaaacg attttctttg ttcgcatccc ctatttgatg ccgatttatt
     5221 gttctttagc attaaatcat tttgaaatag cggttcgtag tgcggctacc ttaggcttag
     5281 ttggcgctgg cggaatcggt gctccattga tattcgcgat tcaaactcgg tcttggagca
     5341 aagtgagtat tattttgatt ggcgtagtcg taaccgtgtt tattttagat caaataaccg
     5401 gaattataag aaagagattg agataagaat gaatatattg catatatcag atatacactt
     5461 tcgcagagag tatgaggctt gtgaagaagg ctataaggga atgctggcta cgatgcagaa
     5521 tccccttatc cctctggagc aatgcattca tcatctcctg cagcaaacac ccttggacct
     5581 tgtgattatc agcggagatt taaccgaaga tggcgaaata gacgattatc gatacttgaa
     5641 gacttggctg gaaaatgcgc taggagaaac gacgattctt gttactctag gcaatcacga
     5701 tatcaaagaa catttttggg taggctggtg cgatgaagcc gcctcttctg ccccgtacaa
     5761 ccagatagtc aaatatcctg agtttacagt gatttccttt gataattcaa gctatggata
     5821 cgcagatggt atagtggacg atcagcaatt tcaatggctg aaaaaagcct tagagcaaga
     5881 aaaagaccaa ccgattttct tggtcaccca tcatcatcta ctgtctcacc aaagcagtat
     5941 accaaaatgg cctggtaccg aacgtttctt gaagctaatc gcaccttacg atattcgctg
     6001 tatcctaaac ggtcataccc atcacacatt tactgatgaa attaatggga tcccctattt
     6061 tactgtatcg agtatgtcct ttgttggtga agatgaaggc gatggcttcg tacgctttga
     6121 agaacgtcat gggtataacc tttatcatct cgatcaagga aggattgttc gccagacaac
     6181 agaaaacttt attccaggca acattttaaa aacacttcaa atgaaggatt aaggcattat
     6241 aaatcaaaaa aagagaccga acagctgaat acgcttcggt ttttctattt tgagtcagct
     6301 aaaggagcac gcagaatgaa cattacgttt ttagagacaa gtgatatgca tggctatgtt
     6361 tcaccaacag actattccgg cagaaccgat ctggccttag gaacggctaa agtatcgtcg
     6421 aaactgaagg aattacgggc aaaagcagat ggaccggtaa ttacgatcga aaatggtgat
     6481 ttcatccaag ggtctccttt gagttattat cttgctaaag aatatggttc agccaaagag
     6541 cttacagact tgattaacca aatgagctat gatgttcaag tgttgggaaa tcatgagttt
     6601 aactatggtg tggattatct cgaggaagcg attaagaatt atcaagcgcc tatattagga
     6661 gccaatatgg tgaacaaaaa tgaccaacca tactttggaa acgcctataa gattatcgaa
     6721 aaggtgggtg taaaaattgc tatcttggga ttaacgacac aatacattcc tcactgggaa
     6781 aagccagaaa ccttagcagg aattacgttt aagagtatcg tcgaaacagc aaaagaatat
     6841 gttcctctat taaggaaaca agcagacttg gtaatcgtta gttaccacgg cggatttgaa
     6901 aaagacttgt taaccggtga ggacacagaa gcgctaactg gagagaatga aggctacgag
     6961 ctattgcagc aggttgaagg cattgacgcc cttttcaccg gtcatcagca ccggaaaatt
     7021 gctgaaacgg ttcatggagt tcccgttgtt caaccaggct atcgtggcga gttcatcggt
     7081 gaaattcgtc ttaccgtcga gaaaaaagag gggcaagtgg ttgttacaga tcaccaggtt
     7141 gctttacact cagttgaaaa atcagagcct gatccagaaa ttcttgcagc gatcgtaccg
     7201 gtagaagaaa aactagagaa atggttggat caacccttag gtaaagtgaa cggaaatatg
     7261 cgtattaatg atccgatgca ggctcgtctt gaggaacatc cctatgtaga gtttattaat
     7321 cgtgtacaat tatttgccag cggctcagag atttctggaa ctgcgttatt caataatgaa
     7381 ggaaaaggct ttggtgagac gatcacgatg cgggacgtca tcaccaacta tatttatccg
     7441 aatactctgg cagtgattca aataaatggt gcagatttga gagcggcgtt ggagcagacc
     7501 gcaaattatt tagctgtaga aaataaccaa atcgtattca atccagcctt tattcagcct
     7561 aagccccagt actacaatta tgacatgtat gaagggattc agtacactat tgatatgaaa
     7621 cagcctgttg gacaacggat taccgaactt cgttttaaag gtcaccccgt tcttccgcaa
     7681 caaatgctgg aagtggtgac aaatcaatat cgggcaatcg gcggaggaaa ttatgcgatg
     7741 tttggtgcgg agaaaattgt ccgagaaatc caaatcgaca tgaccgaatt aattgccgac
     7801 tatttgaata ttcacccacg catcgaagca aaagtgaatc ataattttca agtgattttg
     7861 tagtatataa ataaaaaatt caaaaaggtg tgagcagttt tttgcccaca cctttgttat
     7921 gccaaattgt taggctgtct gatttccatc cagccattct ttagccagcg atctacctca
     7981 tcaaaacaaa aaattttcct ctgatggttc cttaaataag actattttga tcctttttcc
     8041 atgaataaga ttttgcatca gacaatactt catttctgaa aaagttgcgg caccaatata
     8101 gcctaatacc cctttccgat cttgattaaa tacaaaaaat aaatccgctg ctgcgatatt
     8161 taaaaaaaag tcgtcaagat ttctggatac tctttgtcta ggatcggaca tgagcgagga
     8221 taatcaatta attcaatgcc ttttttactg aaatcttttt ccatatctcg atattcttct
     8281 tggaaaacaa tacttccaga aataacagct ttcacaaaat tggcctccat ttttttattt
     8341 ttcagacact ccaccatacc ggatacctct caaagaaaag acatagcaaa aatcaatagc
     8401 agctatctct ccacggtttt ttactggtaa ttttattttt cttttggaaa ttgtatcagg
     8461 aaggtcgttc cttcattttt tcggctggtc acttcaattg aaccgtggtg caggcgcact
     8521 agttccttca cgattgataa tccaagacct gactcgccta tctttgtatt tttacttgac
     8581 ggatcggctt tataatagcg atcccaaatg tttttttgtt cctcttcaat catgccgatg
     8641 ccattgtcct cgacagtaat aaatacaggc tctttgtcaa atgatgttgg taaagagaaa
     8701 tcttagaata atttggacag aacagaaaga agaaactctc tttctgttct gtttatttgg
     8761 ttaaaaatgt tttgccatga cgaatcatga tccgtagttt gaaattgtaa aagctgcgaa
     8821 agccgtacgc attgcgtttt aatactttga tgtggttgtt taaacattcc aatggtccat
     8881 ttgaatagct gtagtgaagc gcattttgga tctgtggcag aaacttttta aacgttcgta
     8941 aagtggttgt ataggtttca ggaagaccgc tgacttctct gtttaaacag tcctcaaata
     9001 atgactgatc tcttttcttt accgcataaa gaatgtcttg gtataactga tagccttggc
     9061 gcaggttggg acaagcagat aacagtcgat cgacaatctc actttcagtc aaataatctt
     9121 taaaactggc acgccaaacc cttttttcgt agtttaactt tgcttcttct ttttgtagga
     9181 gtttccaata gcgtttcaat tttttcccta accctcgttg agagtgggaa gttcctttaa
     9241 gccgtgccgt ggtttctttc actcgatgat tcaagaaggt tctgccaata tgttggacga
     9301 tgtggaaacg gtcgatgatc aactgagcat tcgggaaaag ctttttcacc aatgaaacat
     9361 aaggcgcata catatcaata acaatccatt gaacggcttc acgagtcgct aatgaaaacc
     9421 gagaaaaata gcattctaaa taaggcaagc gtcgattttc gacaatatcc aataatgcat
     9481 ggctttgtcc gtccatcatg ataaaactca ttgcactggc aacacttcga accgatttga
     9541 attcatcaaa gcataagacc tttggcaaag cctgtttgaa aggattcaat gggcggtaga
     9601 atcgcttcat gacacgatag accgaagaag tggaaatatt tttctgacga gcgatttccg
     9661 tcatggaagt attctctttt aagcgagcaa tgacagacca acgaactttt tgactaatga
     9721 aacagtgttt ttcagcaaca gaggtatccg ctacgaatgt tctttggcaa gacttacatt
     9781 taaatcgttg tttcttcaac tccagataag tgcgatactc agacgcatca ttcagtaaca
     9841 accgaacggt tgtcgtcccc caacgaatga tcctagaggg gacgacacaa agacaatggg
     9901 aacactcttc tggcttgtac agaagagttc ctttgtaaat catggatttg agtcaatatc
     9961 ttggacacat tttagtagag acggttaagc cattttttct tttgctaatt cttcaaattc
    10021 ctgtggggtt agatagtgaa tcgagctatg gattcgattt cggttataaa atccttcaat
    10081 gtagctaaat agcgctcgat ttgcttcttc aaaatctgag tagctagtcg tgtagacttc
    10141 ttcttttttc aatgaggcat ggaaagattc gattccagca ttatcataag gtgttccttt
    10201 tctactataa gaatgcctta ttttgttggt tttaagccat tgttccactt ctcttgctgt
    10261 gtattggctg cccaagtcag tgtgtagaat cattccttct ggaatgtgat aatgtatttt
    10321 tgctttattc aatgtttgaa tgacacaatc cacagtcatt cgttttgaaa atgtataact
    10381 aataattttt ttcgtgtgta aatccatgat tgaagataag taacaccaac catttttctt
    10441 agtaggaatg tacgtaatgt cagctgccca tttctcacag atcgtttcag tagaaaagtc
    10501 ctgatttaag agattctctt ttgaaatgat cggtttatta gacctttgag gtctatattt
    10561 tttaactaca atcgacctta aatttaattg tttcattagc ttttggacat gtttaagaga
    10621 tactgaaatc ccttctttta ataaaacttg atggatcttt gtggcaccat agcgttgttt
    10681 attcgtaaaa aaaattgttg aaatcttctt tttcaactta ttatttctga tttctgtagc
    10741 tgtcaacggt ttattcttat aaaaataata gacacttcta gggatttcta ataaccgaca
    10801 taacaaagaa acagtgtaat ccttacacca tttttcaata aattgaacaa gcgaatttag
    10861 gttttccgag agaatatggc tgcggctttt tttaagattt caagttcctc atttaaacga
    10921 gcattttctt ttctcagttc agctacttct tttccagtca gtcctgtgga ctgatcaggt
    10981 aaatataaat tcttccattt gtaaatcgtt gcttcagata agccatattc tttcgctaac
    11041 cctcgaacag aacgtccagt ttgattcagt tcaacaatca tttgtttaaa attttcttca
    11101 tatcgggtca taaaaattca tcctctcgta gataagttta atttattctt gtctctacga
    11161 aaagctgtct aagatttgat actaacacca agttatcttt agaaccattt cagatacata
    11221 tgaaacaatt acatatgatt ttttcataaa aaaacagtac tgtctagtag tataaaatat
    11281 acaaatttct taaaaatttt ttcactaaaa tcactacctg aaacagtcta aaacacttat
    11341 atatcaacgt ttaatgaaac tatctccgtt tcatttcaga tacaaataaa tatagtcggg
    11401 ctccaaatcc gaaaaaaaat acccccagta gcttatccta agctactgga gatgtataag
    11461 tacggtcata taacaacggg gtagggtaaa taaatgaaaa agatggaaga atcattattc
    11521 aataactttt ttaaatactt cgttgtaatc agttacctgt ccgttcttaa ataccacaga
    11581 ataatctttt ttcccatttt caagtaaccg aagtggaatg tctttaccaa cttgctctgt
    11641 cactgcatta ctgatacctg ttagattagc taataaatct gataaagatt gagcatctgt
    11701 agaaatctct gtatcagtat ttatcgtgat tcctttatct tcatttacaa gcttccaagt
    11761 aggtggtata gctgtgtatg tttcgatgaa tgaatcaatt ctttcatcta tcgtcttccc
    11821 agtatctact tctgtctcat tactcttaga tgaatcgatt ctttcatcca tcgtctgctc
    11881 cgtaactgct tctgtctcat tattctcacc ggaaactctc ttcacaccca aacttatata
    11941 ttgtccatct ttagtgtgca tagttaaaat tcccacgctt ttactaataa attcactata
    12001 accagttctt tcaatagaga cttcaatgta tttcacacta tcatactcaa aagaaaaata
    12061 gacatgtaaa agcattttgt tgtttacatc tacataataa tcctttgact ctacttgaga
    12121 ccttcctata cggaatacag ctttactgtc tgatatctct ataccagcat ccttattatt
    12181 aatctgccaa tctccaagta gctcttctgg caagctagta gtttcttgtg aacactttac
    12241 cacttcactg gtagaggtcg aaacattcac ctccgcactg ttagaagaat tttccaagga
    12301 atcaggagcc ttagcacaac caacaagtct ttatatattg tgcagccgat attttcttca
    12361 ttcagtacac ccttgaaata tgcagtgtta gataaagcag ttcgtcctga tttgctgagg
    12421 cacccatctc ttcttgaacg tactccttga ttttcaaggc cgcccgatac tctttcggaa
    12481 aacgctgctt cactgaagcc agcaaaaaat catccttctc cggcaactct tccttcttaa
    12541 tcattcgggc aataaaaaac tgtaaatgcg tcacaaatct taagtaaagc atcgaatctt
    12601 tatcaacctt tttttcggga aacagatatc ctagcatagc caagatatcc tttagtgctc
    12661 ttaccgagag catggtttct tccatatttg cttgttcact ttgggcattt acaatgtgaa
    12721 acgcaatgtt tccagcctcc tcttctggca actgaacatt catttttttg ttgatcaatt
    12781 ggatagcata gcagccgatc tcaaattctt ttgggtaata cttttgaatt tcaatcagca
    12841 ggcgattttg aaaaacaatg cctttttgac tgcgttcaat ggcatgcttc aagtgatcaa
    12901 ccaaggtaaa aaatagactt ttattcagct taaagtcaaa cttggcgttg gcataatcga
    12961 taattcgctt gacgcaaata attagatcat ccggagcagc ctcaaacagt ttaatgtaat
    13021 ccttttttag agcatcagaa agtgaatcta atttaaatac tttttggatt ttgtcagccg
    13081 gaaccaaatc gcctttcttt agttgaaatc caatcccttt ccccatcaaa attacttctt
    13141 tgccttgctt atctaagcaa agaattaaac tgttgtttaa cgttttaatt actctcatta
    13201 gattcaccgt tctctctaag ctaagccatt tcttgcgatt actttttgat accaaaagaa
    13261 gctttctttt tttattcgtt ttaattcttt aagattctca tcggttcggt caacatatat
    13321 aaaaccataa cgcttattga agccttgatg ggtactaaca acatcaatcg ctgaccaagg
    13381 taaataacca aaaacatcta caccatctgt taaagctgct tgaatagcca gaatatgttt
    13441 ggctagataa tcaattcgat cctggtcatt aattcgtcta tcttcctcaa ctatgtcggg
    13501 tgccccatag ccattttcag taattaaaat aggtaaatca tagcgatcgt acaatttcct
    13561 caatgttaat cgtagtccag tagggtcaac tacccagcca tatggcgttt tatctacata
    13621 aggattttca gctgcccggt agacaccttc ttctcccaac atgatctgtt gatcccccgc
    13681 tctagcggaa acatctgatc cgtcattttt gctggcagcg atggtggcag ttgaataata
    13741 attaatcgca ataaaatcgg gtttaccgga ggataaaatt gcctgatcct ctgcctcaat
    13801 tttaggatat aatccacgat cattcaaata gttttcaaac aaataattgt attttccccg
    13861 aactgctaca tctaagaaag accagcctct caatgtttcc caattatggg ctgcaattgc
    13921 atcttctgga ctggaggtag cttgatacat agccgttaaa ttgattgctg gaccgatttt
    13981 tcctttaaga ttcaactgat gatacaagtg aattactcta gcttgagcta ataaaacatg
    14041 gtgattaatt tgaaagagtt ctttttttga aggcagctct ccacttggtg gcaaaccaat
    14101 cgctccagga tgaaggatca tcgtgttttg ctcattaatt gtcagccaat agttcacctt
    14161 gtcaccatac tcagtaagca atacctgtac atagtccaca aaataatcga tagttgctcg
    14221 atttaaccaa ccgccctgct cctctagaaa ataaggtaaa tcgaaatggt acatggtgac
    14281 aatcggttcg attccctgat tcaggcattc atcaattact tgatgataaa aagaaattcc
    14341 cttttgattg gttttattat tttcaatatc cataattcgc gtccaagcga tggaaaagcg
    14401 aaaagctttt aagcctaatt ctttaaacag ctgtatatct tctttatagt gatggtaaaa
    14461 atccgaggca acttcaaaat tagctacccc ttctgtatgc tgatacttgt caataataga
    14521 cggttgtttc ccatcctcct gataggcacc ctctgcctgg taggcactaa tggaggcacc
    14581 ccataaaaac ttctctggaa atgctgaaag ctgtttgtat tgcacaaaaa tcctctcctt
    14641 aactaatttg catcaatggt tcgtgttcct ttaagcttcc gcttgcttca ctaattcctg
    14701 cgtaattttc actgttggtc actaccacaa tcactgtatc atcgtagcca gcgtttctaa
    14761 tggcagcgaa atcggcgttg attaataatt gtcctgctga cacctgatct cctgctttta
    14821 caaatacttc aaagggttcc ccttttaaat tcacggtgtc gatccccaca tggatcaata
    14881 attcaatacc ttctttagaa cgtagaccaa tcgcatgttt agattctaaa atagtaatga
    14941 cttctccctc aacaggtgaa taaatgctgt tttcttctgg atgaatggct acgccctttc
    15001 ccaatagtcc cttagaaaag acagcatcgt tcacttcaga aataggacac acggttcctt
    15061 ttaccggatt ttcaacaatg actgcttcgg ctattgccgt ttgctctgat tcatcagaag
    15121 tatcgtcaaa tccaattaga taagcaatga taaaggttgc aacaaaggcg attacacacg
    15181 taataattgc gtgaacaata ttcattggat tttctccaat aaaggctggt aaggctgcta
    15241 agccagggga aacaaaggca tatctgacta aaccgctcaa gccagcatac aaaccagcaa
    15301 ttgcaccacc aatcatggaa gcaactaatg gttttttcag cttcaaggtt actccataga
    15361 gtgaaggctc agtaattccc attaaagcag tgatcccagt ggacacagct agctgcttca
    15421 actctttgtt tttagttttc gcggctacag caaaggtagc acctgattga gcaatattag
    15481 aagccagcat tcctggccca ttgatcattt cagaacccgt actgctcaat tgcatagtag
    15541 cgattggcgt cattgcccaa gctgtacccg taaccaccaa aaatggctgc aaaccaccca
    15601 tcaaaaatgg aattaaccaa gctgctttgc cgttaatcca ttcagccccc attgctataa
    15661 gatcgttcag caacgttcca aacggtccaa tgacaaccaa cgctaaaggc cccataatta
    15721 aaaataccag catcggctta gtaaagaatt taataaacga aggcgaaatt cgatccgcaa
    15781 agggctctac ataggacatg atccaaacag taaagataat cggtaaaact gatcccgcat
    15841 aatctgcagc taataccgga attcctagaa aagaaacggc atcgccagta gaaaaaagct
    15901 gtgaaatatt tggatgaagc aaaatgccag caacagtaat cgccaaaatt gggttgacat
    15961 caaactttat ggctgcccca taggctaata gtactggcat aaaataaaag gctgcatcag
    16021 caatagtatt caaaatgatg taagtttgac tactgtctga tagtacacca gtcaaagtca
    16081 agacggccaa aatggctttt accatcccgg cacctgttat agctggaatc atcggtgtaa
    16141 aggtggtaga aatgacacta atcaatcttg aaataatact ttcttgattg tctgaagagg
    16201 ggcccttttt aattgaagtt cccacttcct tttgaatttc cttgaaggct gtttggactt
    16261 cattgccaat caccacttgg tattgtccac cgctatccac cacactaatt acaccaagtg
    16321 ttttttctaa ggctttcgta tcggctttcc ttttatcttt gagttcaaaa cgcagtctgg
    16381 tggcacaatg ggttaagctg accacatttt cttttccccc aacctgttgc aatacatttc
    16441 ttcctacttc tctgtaatcc attattctct ctccttaaag cagtaaaaaa gaccaagtca
    16501 aaccacgccc caatcaacat tgaagtgtta gtttgtcttg gtcttgcctg cataatcagt
    16561 aacatgccaa taacgttatt ttgctgtaat ccaataatag cacattatga tagcgcaatc
    16621 aacagggaat ttaatttttt atcttttcgt ttgaccgtat agggtaatat aacagttaga
    16681 tcacatcaac tagggtatat ctgcgtatac ttactgctaa aataagtata tctaatatta
    16741 actataccag taaaaccatt cctacataac cagcgggaaa ttcccaaaat cgtgaaagca
    16801 tcaaaaatgc atataacgga tcacacaact tcaacaattc tgctcttggg aaaaattgat
    16861 gaatttggtg agtaaaggat ggaataaaca gcattccaac aatataggca acaatagtga
    16921 tacttgtttt tttggtaaaa atcagtaagc aatagccaat ttcaatcatt ccgagatata
    16981 aaggtatcga tagaatgatt tgggctagta ttcttaaaaa ttaactagca aatgtttaaa
    17041 ctgatttatt tctaatctac atgtagtaag tatttcaatt ccaccaatt
//
LOCUS       DAFLWQ010000063        16777 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.064, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000063 DAFLWQ010000000
VERSION     DAFLWQ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16777
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.064"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(99..1229)
                     /locus_tag="L1V16_002036"
     CDS             complement(99..1229)
                     /locus_tag="L1V16_002036"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBN1276368.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="L1V16_002037"
     CDS             complement(1878..3080)
                     /locus_tag="L1V16_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1276369.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="L1V16_002038"
     CDS             complement(3140..3343)
                     /locus_tag="L1V16_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HBN1276370.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="L1V16_002039"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="L1V16_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="L1V16_002040"
     CDS             4880..5692
                     /locus_tag="L1V16_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1276371.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6716..6868)
                     /locus_tag="L1V16_002041"
     CDS             complement(6716..6868)
                     /locus_tag="L1V16_002041"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBN1276372.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="L1V16_002042"
     CDS             complement(7059..7937)
                     /locus_tag="L1V16_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1276373.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="L1V16_002043"
     CDS             complement(7976..9094)
                     /locus_tag="L1V16_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBN1276374.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..11190)
                     /locus_tag="L1V16_002044"
     CDS             complement(9091..11190)
                     /locus_tag="L1V16_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HBN1276375.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11241..12062)
                     /locus_tag="L1V16_002045"
     CDS             complement(11241..12062)
                     /locus_tag="L1V16_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1276376.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12059..12868)
                     /locus_tag="L1V16_002046"
     CDS             complement(12059..12868)
                     /locus_tag="L1V16_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1276377.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="L1V16_002047"
     CDS             complement(12889..13383)
                     /locus_tag="L1V16_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1276378.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13883)
                     /locus_tag="L1V16_002048"
     CDS             complement(13395..13883)
                     /locus_tag="L1V16_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1276379.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13960..16656)
                     /locus_tag="L1V16_002049"
     CDS             complement(13960..16656)
                     /locus_tag="L1V16_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1276380.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
BASE COUNT         5102 a         3611 c         2697 g         5367 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttccgtc gtttaactca gcattaaaaa atgggtgttt
    11161 gggtgaataa attacttcat taatagtcat cttttccctc cttgctaaaa aaactgcagc
    11221 ctagtagctg cagcttccta ctatgcgatt ccaagtaatg acaataaaat tcccaagacg
    11281 accattccaa aaataatttt gatgacgccg acttttttat ctagtaattt gaaacagctc
    11341 aatgttacca ataacggtac aattccttta aaaatactat cgaggatttc ttggacattc
    11401 attagttctt cgcccttcat tgaaaagctc aaaacggtat tgaatttgac catactgatc
    11461 gtcattgcac ctaccatgat cagacccaag atactagcag cttttgtcag aatttcaatt
    11521 aacccgttcg catacagctt ttcaatatat ttagagccta atgaatagcc taaaacgccg
    11581 ccatagtatc gcatcaagta attaggtata ttgaacataa ctaaaaagat aattggtgcc
    11641 aaaatatttc cggcattggc taagttgatc gctagtcccg cggtaacgac acgccaaact
    11701 ccccagaaca atgaatcgcc aattccagcc aatggtccca tcaaactcgt tttgatcgcg
    11761 ttgatacttt ccacgtcaaa accagctttt tcagaatttt ccttctccat cgatgccgca
    11821 atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa aatactgtgt atgacgttcc
    11881 agcgccgcag ctcgatcttc ttcacttttg tagaaatgat taatgaaggg catcatagaa
    11941 taggcgaaac caccgccgcc catcgtcacc ggattcaccg aagcatacat agtcatcgag
    12001 cgccaaaaca tcttccgaac caattttttc tcatctttag aaattccatc agctaatttc
    12061 attgaaagaa atcctcctct tcttggtcaa gcgttgcatt tacagcagca tcgctttgaa
    12121 ctgcatgaac agatatattt tttagttgta gatctctttg ggctataaca attgcaataa
    12181 tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag atacgccata acaacggccc
    12241 caaagaaaaa ccacacagca atatttttac tccaaagcat ccgtaacagc atcgccatcc
    12301 caactgccgg cagcagattt ccagcgactg ttaatccgtt catgatgacc tctggaatat
    12361 tatccaagac gcttttgaca acatctgctc caaataaaac ggcaaagaat ggaataagag
    12421 cataaagcgc atagtggaca aaccacataa agaagtgcag attgatgatt cctttttgat
    12481 caccagattt tgcaaatttg aaaaatttag cagccatcgg tccacataca aaagaaaaaa
    12541 tcatattcat taactgtaat cctaatactg ctagtggaaa gacaatggga ataatcgcat
    12601 ccacgtttcc tcccattttg attgcgaacg ctgtagccag cccagcagcc aaagaaggct
    12661 ccgccgtact agagattccg atattgacga cacccataaa gatggcttct agtgacgccc
    12721 cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc tgctaacgga gcaacaacaa
    12781 tcggacgact cagcatggac atcccgaaca tttcatgtcc agcaactcca ataaaaacgg
    12841 ccaaagcgac tacaaatgca tcatacataa tttttctcct tcctttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgcttgc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttaattcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt caaaatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcacttttat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacattaa aaaaagtgtc
    13921 taacctaaaa aaaacagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tagaaacata ataaaattca tcttcatctg gtttcaaatc
    14101 ataattcggt tcttcagatt tttctgtccg agccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata tagagattta gttttacacg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacttcact catcacgatc gttgggttca gaaagttcaa
    14281 acggtccgca attccttcca acgaaaagaa ttttactagc tcctgaatca agcggttaaa
    14341 ttctgccggc ttcatttcag gactcaaaat atgctccaaa ttggctgctc catcaccgtc
    14401 taagatgtca taaacattaa tattaggaat tgaaaaggaa cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtag tccttcgtga aaacttcgat ggattcatcc gataaatgat gacgaaaaac
    14581 atctttcaat ttgtccgaaa tccccaaacc cgacatacag gaaatgataa tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattga
//
LOCUS       DAFLWQ010000064        16163 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.067, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000064 DAFLWQ010000000
VERSION     DAFLWQ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16163
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.067"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..420
                     /gene="scm"
                     /locus_tag="L1V16_002050"
     CDS             <1..420
                     /gene="scm"
                     /locus_tag="L1V16_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBN1276381.1"
                     /translation="STDTSASSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSS
                     TTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKR
                     ALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(575..1561)
                     /locus_tag="L1V16_002051"
     CDS             complement(575..1561)
                     /locus_tag="L1V16_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBN1276382.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1584..2150)
                     /locus_tag="L1V16_002052"
     CDS             complement(1584..2150)
                     /locus_tag="L1V16_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBN1276383.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2164..2580)
                     /locus_tag="L1V16_002053"
     CDS             complement(2164..2580)
                     /locus_tag="L1V16_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBN1276384.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3037..4971)
                     /locus_tag="L1V16_002054"
     CDS             complement(3037..4971)
                     /locus_tag="L1V16_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1276385.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5252..6208
                     /locus_tag="L1V16_002055"
     CDS             5252..6208
                     /locus_tag="L1V16_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBN1276386.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6298..7401
                     /locus_tag="L1V16_002056"
     CDS             6298..7401
                     /locus_tag="L1V16_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBN1276387.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7414..8367
                     /gene="menA"
                     /locus_tag="L1V16_002057"
     CDS             7414..8367
                     /gene="menA"
                     /locus_tag="L1V16_002057"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBN1276388.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9181..10527)
                     /gene="gor"
                     /locus_tag="L1V16_002058"
     CDS             complement(9181..10527)
                     /gene="gor"
                     /locus_tag="L1V16_002058"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBN1276389.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10661..11914)
                     /locus_tag="L1V16_002059"
     CDS             complement(10661..11914)
                     /locus_tag="L1V16_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBN1276390.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(11920..12843)
                     /locus_tag="L1V16_002060"
     CDS             complement(11920..12843)
                     /locus_tag="L1V16_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBN1276391.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13064..15556)
                     /locus_tag="L1V16_002061"
     CDS             complement(13064..15556)
                     /locus_tag="L1V16_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBN1276392.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15563..16030)
                     /locus_tag="L1V16_002062"
     CDS             complement(15563..16030)
                     /locus_tag="L1V16_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBN1276393.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
BASE COUNT         4746 a         3377 c         2874 g         5166 t
ORIGIN      
        1 agcacggaca cgtcagcttc aagtgacagt acagatacta cctctaccac aagtgatagc
       61 tcagattcat ctaccactac aagtgatagc acggacacgt cagcttcaag tgacagtaca
      121 gatacatcct ctaccacaag tgatagctca gattcatcaa cttcaagcga tagtacagac
      181 acgtcgtcta ccacaagcga tacacgtcat gcaagtgtct ccttctcaaa aacaagttcg
      241 gataacagga cgaactttaa cttaactaat aaaacaagca atgacaatgg aaacaaatca
      301 aaaagagcac ttcctaaaac tggaagtcaa tcgaataatt ggataacact cgcaggcgtt
      361 atattacttg taatcggttt aagaatcact tttatgagtt ataagaaatc gaaaaggtaa
      421 aaaaatattc aagataaaaa agagcaacgt cgctaacgga cgttgctctt tatttttgct
      481 ttttatcata aatacaagaa ctacaattca atttgtcaaa aaacacgtag atttccttct
      541 gagaaattta tttacgtatc gaacctttcc ctattcagtc tttgcgatcc aaaatcagtt
      601 gggtaaggga aaagagattc tcttttgttc gaagagaggt ggcaggtaat ttctttattt
      661 ccttcaaagc cttttctgtg taagaggccg ctaacttcct agcttcttcc acgcctcctg
      721 tatgttcaac gattttgcgt acggcgtcga catcttcttc tgtcattgcc gctttcttct
      781 ctaaataagg tagtagcttt ggtttgtttt tttgcaaaga gtagatcaac ggtaaagaat
      841 agaccccttg acgcatgtct tctagtacag gtttgccgat ttcctggctc tcttttgtat
      901 aatctaaaat atcatcgata atctgaaagg ccatcccgat agaaagtccg atatctcctg
      961 ctttttttgc gaagcgctcg cttgttccac tttcaaaagc gccaacagaa caacttaatt
     1021 ggaacagttc agctgtctta cctgaaatat tttccaaata ttcttttaca gaaagttcat
     1081 aattatagcg atcatccatc tgccctaatt cgccattcaa tactttttcc atactgcgag
     1141 aattcaattg gagacttttc aaggaagtgg agtaatcaga caatagttta aaacagcaga
     1201 caaataaata gtctcctgca tagacagaaa cgacattacc aaactgacta cggatattag
     1261 gctgaccacg tcgcagatcc gcttcatcaa cgatatcatc atggatcagt gtggccgtat
     1321 ggagcatttc gatagaagct gccaaagcga tggctttgtc tcgatcttgc tctggtccaa
     1381 attgtgagaa caatagctga taggcaggac gcaacagctt tccgccggca tggatcgttt
     1441 ctttgattgc ttgttcgaca ggtttgtttt tcaggcggac agtttcttcc atccgtttta
     1501 gtgtttctgt caattcttta cttaaagcag gatagttttc ccacattgga tgtagcttca
     1561 taaaaaaact ccttgtgtga cgattatttt ttggtaaaca ttgggctcca tttttgtttg
     1621 gttccctgct cataatcttt ttggaatcgt tgaagtgtct gcacatgtcg taaaagataa
     1681 ttcgctgcga tcccgattgc aatccctgat aaaatcccta aaactgaaag gactggcaag
     1741 tacaacatga ctgtccatga ttgtgcaatg aaagaagcca tcaaaagctg tccgacatta
     1801 tgcatgaaac cgccggccgc actaattccg atgatactga cacgttttgg tcctaattgc
     1861 ttgaccaata acattccaaa ataactaagc aaagcaccac tcatactata aaggaatgtg
     1921 gaaatcgttc cgcctagcaa agtagtcagg aatagtcgta gccaaagtag taagaagctg
     1981 tcttgttttt tcatggtaaa aatggcaacg atcgtgatta gattggctaa gcctagtttt
     2041 gcaccaggcg caaaagaaaa aggataaggg atcatatttt ccaataaacc aatgatcact
     2101 ccttgtgcaa caagtagcga aatataaatc attttttgta atttactcat ggtgtgtaaa
     2161 ggtctaataa atcagactgt cttcgtcacc tccatctgtt gaacggactt cgatcactaa
     2221 tttatgtggc aaacagacga tggtttcgcc atttttcgtt gcccagcctc gacgtacgca
     2281 gatctggtca tcgcaatctg cttcttttat ccgtactcga tcgccatcta tctcgatcaa
     2341 gttataatct ccgtgttcat ctttgtaagt atatgtgttg ctctcttctc cagccatcaa
     2401 agggaatgtt ttgatttctg tgccatccac acgcagtacc gcttcttttt ctgctgttgc
     2461 ggtgttttgc tgaagaccaa aaatcatgac tggtaaaaaa gaaagaacag tcaaaagcaa
     2521 aataataaaa acatcccaag gtttgagcag acttttttca gcaaattctt taaggctcat
     2581 ttttgttctc ctttttccag attaactcac ccaattttag cataaaaaca agaggttgtg
     2641 acacctgtgt cttgctttga gtaataagaa cgaagaatag aaaacagctt tccatgtttt
     2701 ctaattcttt gggcttatta ccgagaagca gcaggtggaa caccgtttat aacaagaggt
     2761 tgtgacagaa gtgggcaact tcaagaaata agaaggaatt tacgaaaatt acttttcaag
     2821 tttttgtgaa atttcggctt atttttcgaa gaagctactt ctggaacacc gtttataaca
     2881 agaggttgta acagaggttg tgacacctgt gtcttgctca tggaggctta tctcgggcat
     2941 cttattcctt taattttaca taaaaaggag gctgtgacgg tttgtctcag cccctttcta
     3001 ttgaaatctt gcattcaaat aacgttcttt atctatttat ttcttgccgt actgggaact
     3061 tggtctaccg taccaccaat tacctagtgt acgttgtagc catggaatta cccagcgatc
     3121 caacccaatc gcacgtccgg aaccgttcat caatgcgaaa gcaacaaaaa tgaaccaaat
     3181 gtttacccag taaaacatgc ctgataagca gaacgtgatc accaatacaa tcgttgtcgc
     3241 actgcatagc catgtgaata atccagcaat caatgctaat gccaaggcaa tttcaaagaa
     3301 taccatgaat ttttggaaga acattgctac atcattgttt ggcatgatca cttgcatgat
     3361 ctttgtgaac cagtctggtg acttctcaat cacagccatt ggttcttcac cgtatgcata
     3421 actcaaacca aaatgtgcag cttgagtcgc tgcttctccg gcacttgccc ctgctccgct
     3481 ggcagctgtg gttgcatcac cagcagcaga agcaccactg gcaacatctg ttacattgta
     3541 ttcccatgtc caagggaaca cactgtttcc agtgaaccat gatccttcac caaaccaagt
     3601 acttggtttg aacacttcac cattcccaat gatttttttg gaagcttcaa cgaaccaaac
     3661 taaaccatag aaaatacgaa gtggcacact ccataagaca ttgccgtaac gagaagaatg
     3721 tcctcgagtc acgttgcgat catctttgat atggaaaaac tcatgcatta aatattggaa
     3781 catataataa ccagaacgaa tatcaaagaa gtatttcaaa ttcacgatat gtttcattac
     3841 gatagctaaa aatccgctta aatggatctt atcaaatagg ttagctaccc cccatttggc
     3901 accaatagaa accataaatc cttgatagtt tcctttaaat ttatgctttt ctccgccttt
     3961 gatcgaagcc acgatattcg ctgcggctgt gtgtcctgtt tgttcagcag cttgaacgat
     4021 ctgcggtgtc ggtgttcctg ggaattcttc ataaaagact aaatcaccaa tgatatagat
     4081 gtttttatct tcgtagcctt ttgcctgcat atattcattg gcgatcaacc gctgtccgcg
     4141 tgctgattct aatccaaagt cagcagcgtc agaagttcct ttgacaccag ctgtccaaat
     4201 cagtgtgtga gtcggaatgt tgcgtccgtc tttcaatttg atatgatcag cagccacttc
     4261 tacgattggt gcattcaata ataattccac gttgtgctta cgcaaatagc gttcagcttt
     4321 tgcagcatca tttcgatcca acatattcaa gatcgtcggc attgcctcta cgaccatcag
     4381 tgtgatttcg tttggatcta atttataatc tttggctagg cgatttttcc agtcgatcag
     4441 ttccccaatc atttcaatac cggtaaatcc agaaccacag acaacgaaag tcagcatggc
     4501 tttacgcagt tcatcatctg gttccaatgc agcttttgct actgtcttct caatatgttc
     4561 ccgaatcctt acagaatctt caaatgacca aagggtgaat ccgtgtgctt tgacaccagg
     4621 tgtaccaaag tcattcggct ctccgcccat tccaaggatc agctgatcaa aaggatagga
     4681 acctaatttg gtcttgacga tttttcgttc tttatcgata ccgattacag tgtctgtgac
     4741 aagttgtaca ttcttttgac gagcaaacaa atgctgcaga tcgtattgga ttgcttctgg
     4801 ttctacacgt ccgccagcta cttcatgcaa ctcggtcatc atagtatggt acgaatgacg
     4861 atcgatcaga gtaattgcta catcttcttt tttcagtttc tttgccaagt attttgtagc
     4921 tgaaacaccg gcatatcctg ctcctacaac gacaatattt tgctttgcca ttgatcatcc
     4981 gctccttata gactatctat ataatgaata tatgataatt cttttagttt gatacttatt
     5041 acacaatctc catatattat atagatgttc tgttcttttg tctaactcct tttggatttt
     5101 tttcaaattt taaaataaag cgttttttca cgaaatttgc tgaaagaaaa cgtttgaaat
     5161 attacatggg ttatttatca aaaatagttg acttataggc taaaaagatt agaatgtata
     5221 atgaatcaca aagaaaaatt gtggactaga aatggaatgg tggggtatta aaatgaagaa
     5281 aaaacgtttt gtaactggat ttgccgtatt agcattttca gctctagtgt taggcgcttg
     5341 cggcgcagat gacaacggaa gctcaaactc ttcttctgaa tcatctacag cacaatcttc
     5401 gactgcaaaa agcacaacag aatcatctgc aaaagttgta gctggcggag atttgcaaga
     5461 cggcacatat aaattagaag aaaaaaatta ttcaaatggt taccgtgcag tctttgaaat
     5521 ggttgtaaaa gacggcaaaa tcactgaatc aaaatatgat aacgtcaatg aaaacggcga
     5581 atcaaaaaca aaagatgcag aatacaacaa aaacatggaa gcaaaatctg gcacaaaccc
     5641 agaaaaatac attcctgagt tgaatgacca attcttaaaa gcacaaagcg caagcggtgt
     5701 ggaagtcgta actggagcta ctcactcatc tgaaagcttc caaaactacg cacaacaatt
     5761 gatccaagct gctcaagctg gtaacacaga tacaatcgaa atcgacaatg gtgctgattt
     5821 gaaagacggc acttacaagc ttgaagaaaa gaactactct aacggctacc gtgtgcaatt
     5881 cgaaatgaca gttgctggcg gcaaagtaac tgaatcaaac tttgattata tcgacaaaga
     5941 cggtaaatca aaacaagatg atacagaata taatgaaaat atgaaagcaa aaagcggtac
     6001 agaaccaaaa acttacatcc ctactctgaa cgacgaattc gtcaaagcaa tgggcgaaga
     6061 agatggctca cctgctaatg tagaagttgt tacaggtgct acacacagct cacattcatt
     6121 catcatgtac gcacaacaat tagtgaatgc agctgaaaaa ggcgacactc aaacaatcga
     6181 agtagataat atcgtaacag aaaaataatc acataatcat actaataaaa gttggagggt
     6241 gggacgatag ccagattagg cagtcgtctc acctttcaaa atgaagagag gaaaaagatg
     6301 cggaaaaaac tactattttc cttaatcaca ctgggcatct cttttatggt gctaactggc
     6361 tgcagcaact cagcaaataa aacaaccact gaaagttcag cagctaccaa gatattgaaa
     6421 gatccatatt ctgatgaaca gttcttgtta gggacttacg ttcgtatccg tgtgtatgat
     6481 gaaggcaaag aatcagcatt gaaacctgcc ttcgatcgag taaaagaact tggtgataaa
     6541 atcacgatca atcaaaaagg ttctgagatc gatgaagtga atgagcaagc tgggatcaaa
     6601 ccagtaaaag tttctgatga cgtctacacg ttagtcaagc gggcctacga atatagccaa
     6661 gattctcaag gcggattcga tatggcgatt ggtgcaatca cacaattatg gcgaatcggt
     6721 tttgatgacg ccagaaaacc ttcccaagaa gaaatcgatc aggcattgaa attagtggat
     6781 tatcataaga tcgaactaaa tgacaaagaa aaaactgttt atctaaaaga aaaaggaatg
     6841 atcatcgatt taggtgcaat cgccaaaggt tacattacgg acgaagtagt gaaagtcttg
     6901 aaaaaacaag gagtgaccac tgccatcgtt gacttgggcg gtaatgtcta tgtcttaggc
     6961 cacagcccaa gaggcgaaaa ccaagactgg acagtcggca tccaagatcc gaacatggct
     7021 cgcggatctg ttttaggttc tattaaagaa cggaacaaaa cattagttac ctctggaatt
     7081 tacgagcgtt atttagaagt agatggcaaa aaataccatc atttgtttga tccaaaaacg
     7141 ggttatccgt tcgacaatga tatcgcaagt gtcacgatca taacagataa atcaattgat
     7201 ggtgacgggt tgtctacagc agtcttttca atgggtgtga aaaaaggact ggaatacgtc
     7261 gaaagcgaat tgaataacgg gacggaagcg atcttcgtga caaaagacga taaagtatat
     7321 gtgaccgatc caatcaaaga caccttcaaa ttatcggagg actcccatta cacgatgggt
     7381 gaccgttctg aactaaaata aggagtacga accatgacac taaaaatctt tttagaagta
     7441 gttgaaatac gaacaaaggt ggctagtgta tttccttttg cggtaggggt attattctct
     7501 atcgcttttt ttcatgagat acattggcta aacacttttt tattttttat tggaatgcta
     7561 gtttttgatt tagcgactac cgctatcaat aattacatgg attatgaaaa ggctcattct
     7621 gaagtatata agtatgaaga aaatgtcatt ggccgcagaa atctatctcc tgtattgatt
     7681 cgaaacatga ttttagctat gattgcattt gtttttgtta tcggcgttat tctaacgatc
     7741 aatacgggtt ggcttttact tttgatggga tttatctgtt gttttattgg agtattctat
     7801 acattcggac cgattccttt atctcgaatg cctttagggg aaattttcag tggggtgact
     7861 atgggccttg gaatttttgc catggtcgtt tatgtcaata cattcggttc agatgtctat
     7921 gatctgacag tcaacttttc atctggacaa tttgctttgg taggaaatct ttgggctata
     7981 gcagcaatcg tattagcttc cttacccttg gtgtttacga ttgccaatat catgttggct
     8041 aataatttgc gggatcttga ccgtgatatt gaaaatcatc gctatacact agttttttat
     8101 atcggacgtc ctgcgggaac agtcttattc cagctattga tgtatgcttg ctatttcgtg
     8161 attttaatgg ggttgttgag cggtatctat gaatggccga tcttggtcac cttcttgacc
     8221 ttgccaattg tgaagaagca tttggatcaa ttcaagcaaa cgttacccca gcctatcagt
     8281 ttcagctatt ccatcaaaaa tatggtctta ttcaatgcca gttatgtatt ggggctatta
     8341 ctaacaatca ttatgcaagc catttaacag catgaagagg ttgtgaaaaa actgccctgc
     8401 atcaagtaat aagaacagcc aaataaaaat agctccttat atttttcgtt tggttgggct
     8461 tattaccgca gatgcaagct tttgaacacc gtttatcagg aggttgtgaa aaagtcgctt
     8521 agtttcgagt attaagaaaa attttgtgaa aatggctttc cacatttttg cataaatttg
     8581 gcttaatacc gagaaactgg cttttgaaca ccgtttatca gaggttgtaa aatcagtgtt
     8641 ttgtcctgag tattagagaa acaaatggaa aaatagttcc tcatattttg ccgttttttg
     8701 agctaatacc gaaggacagc tgattgaaca ctatttgttc ggaaaaagtg actaactatg
     8761 acacaatttt tttcacagtc ccttttttca cttgatttga ttcgtaccag cgaacttgac
     8821 gagaactttc ttggtttggt aactatatgg tattctttta acatcctcgt ttgcttcttc
     8881 taatttattt atacaaagtc acactttttt aaacatctgt tcttcgatac atttctattt
     8941 cttttaaaca tcgataccaa tattttgaac ttaagagtgc ataccaaatg gattcattta
     9001 ctcttcgtca gttacgaaga taatcaaaat ctccaacttc cctacttatt tcgttttgag
     9061 aattatcgaa gcaatcttac ataaataact aaaaaacaaa aaaccagaaa atcagtatac
     9121 tgattttctg gttttacatg gtttgttcaa taaaaagctg ttggaactgt taatattaaa
     9181 ttatcgcatc gttacgaatt cttccgctcc tgttggatgg atggctactg tattgtcaaa
     9241 gtcttcttta gttgcaccca tcttgatagc cacggcaaaa ccttgcagca tctcatcgac
     9301 accaacacca atagcatgta agccgacgat tctttcttct tttccgacac agatcaattt
     9361 catttcgcat ttttggcgat aatcatttaa tgcaaagtac attggggtaa agcgtgaacg
     9421 ataaactttc aattcatttt cgccatattt ttccaatgct tcttcttctg tcaaaccaat
     9481 tgttgcaatt ggtggatgcg taaagacgac tgtcggaaca agtttatagt caagataaga
     9541 atctttcttt ccattaaata aacgttctga taaacgtcta ccagctgcga ttgcaacagg
     9601 agtcagatct aatttaccga tcacatcacc aacagcaaaa atatgttcat ccgttgtatt
     9661 ttggtattta tctactttga taaacccttt tttgtccaat tccacatttg tattttccag
     9721 acctaatttt tcggtattcg gtacacgtcc accggcaaaa agtacacaat caccagttaa
     9781 ggtttcacca ttttcaaata gcaccgtata ttcgtcattg tttttagtaa tttctttagc
     9841 aatatgatgt gcgtaagttt ttattccagc ttcttggtac atttggatca aattgtccga
     9901 aagcatttta tcaaacgttc taagtggtcg ttcttttcga tatgcccaca tgacttcact
     9961 acctaaacca cgaaatacac ctgaaagttc agccgcaatg tatccagcac ctaaaacgat
    10021 tgctctctta ggtaactctg ttaattcaaa aaatccattt gaatcaattg cgtattctcc
    10081 accaggaatg gtcattttac ttgcacggcc tccagtagcg atcaagattt taggagcacg
    10141 ataggtttca ccgtttactt cgatcgtttg actatcgata aaagtagcgt aaccttttat
    10201 agcctcgaca tgattgctat ctaatcctct ttgataagca ccgtgtagaa aatcaatata
    10261 tttttctcgt ctttctacta gaccggcgaa atcaacattt tttaaatctg cttggatacc
    10321 gtaacttgag gcatctcgtt caattgtttc caaaatcgta cttgcttgcc acataacttt
    10381 tttaggtaca caaccgacgt tgacacatgt tccgcccaat tcattcgctt caatcagcaa
    10441 aacttttgcg ccatgcatcc ctgctctgtt tgctgaagca ataccgccag agccgccacc
    10501 aattacgatg taatcatata tttgcatttt gttcctcctt attgaagaga tcaatcaaaa
    10561 cctttattta acgatccttt ttctacagaa aacaagtgta acacttttct tgaattttgt
    10621 atgcgaagat gcttaaaaca gggatatatc agctttttcc ttatttacgt tttcggatca
    10681 tatctccagg tttcaccggc tgtgcgactg gcatagttaa aatcatcatt ggatttggtg
    10741 ctcggtcaat ggattcgcct tcttcattat gcataacttc aacggtttga ctgaaatgac
    10801 tgaatcctgg accataaaat tcgatttcat ctcctacaga aaacaagttt ctctgacgta
    10861 tcgtagcaat ctgtgttgcc tcatcataag ataatacttc accgacaaat ttatatactg
    10921 ggattttacg acgttcaccg aataattgtt cgttttcagt tggtgtattg tagtaaaaac
    10981 ctgtagctaa ttctcgttgt gctactttcc ataactcgtc gatccattct tgcttgcaga
    11041 catagttttc aggatcttcc atataactgt ctacagccgc tttatagaca tttgacaccg
    11101 tagatacata atggatcgat ttcattcttc cttcgatctt gaagctgtct acgccgtttt
    11161 caatcaattc tggaatatgt tcgatcattg acatatccac tgcactcatc gagaattctt
    11221 cttccacttc gcctgtatca gttaaactgt ttcgttcttg accaaaaggc atatcgaaca
    11281 atccatactt ccagcgacaa gattgagaac atccgccacg gtttgcatcc cgcatcgaca
    11341 tatggttgga caatgtgcat cgaccagaat aagagataca catggcacca tggataaatg
    11401 cttcgatttc ggtatccgta tttttacgaa tctctgccac ttcctccatt gaaacttcac
    11461 gagctaaaac gacacgttcc aacccttctt ctttccagaa ttccaatgtc tcaaaattag
    11521 ttgctgaagc ttgagtggat aaatggatcg gcagacctgg ggcttctgtc gcacaaattt
    11581 cgatcaaagc tggatcagaa acaatcactg cagaaatacc gacatcacgc aaactgcgga
    11641 aaaattcccc tgctccatct tcatttcctt catgggtgac catattagca gcaacgtata
    11701 ccttcgcatc atgttctttt gcaaaagcaa ctccttcagc catttcttca taagtaaaat
    11761 tacctgcacg gcttcttaaa ccatatgcat tcccgccaat atatactgca tctgctccat
    11821 aatggatcgc ggtttttaac ttttccagtg ttcctgctgg cgctaggatt tctggtcgtt
    11881 tcaattttct ttttactgtc atttctttca tcatactcct tatttgatag cagaaggatc
    11941 aatataaaag aatcctgtat ctaattcacg gttttcagga tgcaatttac tgatttcgct
    12001 agtcattttt tccgcttttt cttgatccca gctaccttct aaaatttgtt tttttgcttc
    12061 ggcgaatagt cgagtgatgt ttacgaattt ttcgcctgga gtaaataatc cgtccaattt
    12121 ccatgtacag taatgatgct gataaagttc attcaattca ttcgagagat tcagatcatt
    12181 gctggcaaaa atatgtgtgc catgactatc ttcataaata gaataatgtg tctcttcttt
    12241 tttaggttcc gagataaaaa gacctctttc acgatctttt tgttcgtctt gtttcgtata
    12301 gttatagtaa ttctgtagca gtggacgttt ggattgatgg atgcatgtag caccatacac
    12361 aagggtttct acaggaatat cgagtttttc ttccatcgcc ttcatctctt caaaaggaac
    12421 ttcacgagca agtactgctc caactgcgcc ttttttcgcc cagaaattga tttgacgtgc
    12481 gctcgttact aatgtttcag catcataaat atacggtata cgcaattcag gatttttttt
    12541 catcgtataa ataatacctg tatcaccaac tgtgatcaca tctacgttta tttcttttaa
    12601 aaaagccaaa tattcaggta catttttcat tttttcagga tgaatgatcc catttacagc
    12661 aatattcgct tttttaccat acttgtgtgc taattctacc aattgtcgct gttcttctcg
    12721 tgtaaatgaa gcaggcagac gcaatccaaa ttgctcttca ccgaaatata gtgtatctgc
    12781 acctgcagca agcaactgtt ctgcttgttc aatagtttct actgtggtta tgagttcgat
    12841 cataattttc tcctcctaca acttcataat agtagcatag ctctaaaaac tttccaatac
    12901 ttcttctatt taaagtcgga tttttgaaaa ttatttcaca aaaaatcaaa ataaagttcg
    12961 atatattctg tccaaatata aaaagagatt gtgacaaaaa tcttgtcaca acctcttaat
    13021 caagtcttac tattataaaa attcagctac acaggccaag taactatagg gaacctactg
    13081 tttccttttt aggtccgcga acattcaatg tgatcttacc ttttgaagca cctactgtta
    13141 cgtggtcacc taaacgaatt tctccgccaa gcaaagcctc gctcaatcga tcttcaattt
    13201 ctttttgaag tgcgcgacgg attggacgtg caccatattc aggatcaaat ccagctttcc
    13261 cgatcacatc gattgcagat ggtgtgattt tcacttgaat atcttgttct ttcaatcgtt
    13321 tgataatcgc tttgctcatg atttggacga ttgtatggat ttcatcttta ctcaatgaat
    13381 ggaagacgac agtctcatcg attcgattca agaattcagg tcggaaagct ttctttaact
    13441 cttctaagat acgtttttgc atggctttgt gatctttagt aacatcttgg acattgaatc
    13501 cgacattttt ttcttctcga atttgtgtcg ctccgatatt tgaagtcata atcatgattg
    13561 tatttctaaa gtccactttt ctacctttag aatctgttaa atgaccatca tccaatactt
    13621 gcagaagtaa attgaaaacg tctggatgtg ctttctccac ttcatctaag agaatcactg
    13681 aatatggttt ttgacgaatt ttttctgtca actgtccacc ttcatcatac cctacgtatc
    13741 ctggaggaga cccgattaat cggcttgtac tgtatttttc cataaattct gacatatcaa
    13801 cacggatcag ggcatcttca cttccaaaca tgacttctga aagtgctttg gccaattctg
    13861 tttttccgac accagttggt ccaaggaaca tgaatgaacc aattggacga tcaggatctt
    13921 tcaatccgct tcgtgcacgg cggatcgcac gtgaaactgc tttgacagcc tcatcttgac
    13981 caacgacacg ttcatgcaga agtccttcca gttctaacaa gcgttcgctt tcttttttct
    14041 ccaactgctg tagagggaca ccagtccact ccgatacaac tgtagcaaca tcttcttctg
    14101 ttacacgatc agaataacct tgctcctgtt ttgcttcaat tgcagaaact ttttgcagct
    14161 ttttacgtag tgctttttct tgtctgcgta attgagcagc attttcaaag tcttgttttt
    14221 ggatcgctgc ttccttttct tgtactagtt catcgatttc tagtttgatc acagttgatt
    14281 ttgttaagtg atcggtttga tccaaacgga ctttcgctgc tgattcatcg atcaaatcaa
    14341 ttgctttatc gggtagttga cgagaagtga tataacgaac agaaagattg actgctgctc
    14401 gtacagcttc atctgtgatc tccactccat ggtgctcttc atatcttgta cgtaatcctt
    14461 gaagaatcac ttctgcttct tcaggagttg gctcatctac ttgaatgcga gcaaaacgtc
    14521 gctctaatgc agaatctttt tcgatatatt tttgatattc atctagggtc gttgctccga
    14581 tcgtttgtaa ttctcctcga gctaacgccg gtttcaagat attcgaagca tcaattgctc
    14641 cttctgctcc acctgcacca attaaggtat gcaattcatc aatgaataag attacttgac
    14701 catcattata gatttcgtcg atgacctttt tcattcgatc ttcaaattca ccgcgatatt
    14761 tcgtaccagc aaccaaagat cccatatcaa gcatcatcag gcgcttttct tgcatgtctt
    14821 ctggcacttc acctaaaatg attttttgag ctaacccttc agcaatggct gttttgccta
    14881 caccaggttc acccaccagt acagggttat tctttgtccg tcggctaaga atctggataa
    14941 gccgtttcac ttctctcgaa cgaccaacaa ctgggtccag cttgttttct tttgctaatt
    15001 tcgtcaaatc acgtgctaat gaatctagcg taggtgttcc ttgcggtgtt tgccgtttat
    15061 cttgtacatt tacatttcta cgacgattca ttccttttcc agcagaatca ccagctagcc
    15121 ccattttttg tttcagaact tgacgggctt ttgaaaggct gatacctaag ttgatcatga
    15181 ttcgagtagc catgatactt tcatctttta ataagctcat caaaatatgt tctgttccaa
    15241 ctttttgaga accagttttc ttcacttcgc tgctagctaa agcaaaaact tgtttcattc
    15301 ttggtgaata tggaagaaag actcctttag ggtaagaacg gataccacca taaccaatca
    15361 gatgttcaat ttcttcataa atttccgttt cattcaaatc catttcacgt aatacttttc
    15421 cagcaattcc attttgctcg accactaagg ctagtaaaac atgttctgaa ctaactgatt
    15481 gatgtttcaa ccgttttgct tcttcttgtg caatttctaa tactgcttgg gctctttcag
    15541 taaaaagttc ttccatctaa tctcacttcc catcttcata acttaaacgt tccagaaatg
    15601 ctcggagaat ccgagcacgt gtatgatctt catattcatt gaaattcaat gtgttttttg
    15661 caattgcact caacatcaag tttccttctt tttttgtaat tatttggtct tcataaagtt
    15721 tttgaataat agcaaaagca tttttctcac tgattgtatc atcaaataac tgatttatct
    15781 gctcaagtaa ttgtttttta tctgaaatcc ttacttttgc aattcgtata taaccaccac
    15841 caccacgttt gctttctact agataaccac gttggatggt aaaacgggta ttaatcacat
    15901 agttgatttg tgaaggaaca cagttaaaga ggtctgccat ttcaatcctt cgaatctcga
    15961 tcatttcact attttccaga attttcttta tatatgattc aattaaatcc gaggtattct
    16021 gatgtgccat cttattcatt ccctttgact aatattgacc ttaattataa cgaatttgat
    16081 aatagaaaga aagaagaacg ctttttgtta aataaatcct ttagaatcaa caaaaaaaaa
    16141 tacggaatat actattccgt atc
//
LOCUS       DAFLWQ010000065        15989 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.068, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000065 DAFLWQ010000000
VERSION     DAFLWQ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15989
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.068"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            226..894
                     /locus_tag="L1V16_002063"
     CDS             226..894
                     /locus_tag="L1V16_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBN1276394.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(1094..1324)
                     /locus_tag="L1V16_002064"
     CDS             complement(1094..1324)
                     /locus_tag="L1V16_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276395.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(1451..2833)
                     /locus_tag="L1V16_002065"
     CDS             complement(1451..2833)
                     /locus_tag="L1V16_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBN1276396.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(2989..4176)
                     /locus_tag="L1V16_002066"
     CDS             complement(2989..4176)
                     /locus_tag="L1V16_002066"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBN1276397.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(4183..5214)
                     /locus_tag="L1V16_002067"
     CDS             complement(4183..5214)
                     /locus_tag="L1V16_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBN1276398.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(5260..6684)
                     /locus_tag="L1V16_002068"
     CDS             complement(5260..6684)
                     /locus_tag="L1V16_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1276399.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            6859..7764
                     /locus_tag="L1V16_002069"
     CDS             6859..7764
                     /locus_tag="L1V16_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBN1276400.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            7855..8532
                     /locus_tag="L1V16_002070"
     CDS             7855..8532
                     /locus_tag="L1V16_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBN1276401.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            8529..8699
                     /locus_tag="L1V16_002071"
     CDS             8529..8699
                     /locus_tag="L1V16_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276402.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            8813..9709
                     /locus_tag="L1V16_002072"
     CDS             8813..9709
                     /locus_tag="L1V16_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBN1276403.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(9764..11134)
                     /locus_tag="L1V16_002073"
     CDS             complement(9764..11134)
                     /locus_tag="L1V16_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1276404.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            11372..12118
                     /locus_tag="L1V16_002074"
     CDS             11372..12118
                     /locus_tag="L1V16_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBN1276405.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            12115..12954
                     /locus_tag="L1V16_002075"
     CDS             12115..12954
                     /locus_tag="L1V16_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBN1276406.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            12955..13905
                     /locus_tag="L1V16_002076"
     CDS             12955..13905
                     /locus_tag="L1V16_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBN1276407.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            14046..14798
                     /locus_tag="L1V16_002077"
     CDS             14046..14798
                     /locus_tag="L1V16_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276408.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            14817..15968
                     /gene="queG"
                     /locus_tag="L1V16_002078"
     CDS             14817..15968
                     /gene="queG"
                     /locus_tag="L1V16_002078"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBN1276409.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT         5191 a         2996 c         3221 g         4581 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacggt tgtgtaaaaa tatcatttta gagcataaaa
       61 aaaaggagtg gatttctcca ctccaaaaaa gtctaacttt tgggggtcac tacagtgtca
      121 cagtcctttt tttagtaaaa ggatacattt cttccttgta tattccatgc gtgttcgtga
      181 gaaagcatat ataatttaat taacagatag ttagggggag aaaaaatgat tttttcaatt
      241 acaatgaaac tggtgttcgg gttgatcggt ttattattag tggtacgttt gcttgggaag
      301 aaatccatgt cagaaatcac accgtttgat ttagtctata cgcttgtttt aggtgggatc
      361 ttagaagaat caacctatga tgacaatgtc catgtagggc atgtcctatt tgccattgcg
      421 ctttgggcag taatgattta tggtatcgaa cgtatcgtcc aaaaaaatga aaaggtcaat
      481 cgttgggtca aaggcgagcc atctgttcta atcaaagacg gcgtcatcaa catgacagag
      541 ttgacaaata accatatcga gatggagcag ttgcgagcaa tcttaagaca gcaagaatgc
      601 ttttttcttg aaaatgccaa acatgttatc ctagagaatg ccggtcaaat gagtgtattg
      661 aaaaaatcag atgaagacaa agctttatcg atcctgcttg tagatgaagg gcaaattcag
      721 cataaagtgc ttcagtccaa tcaattgact gaagcatggc ttatggagaa cttgaagaaa
      781 gaaggctatg cagatgtaaa acagctgatt tatgttgaat ggtcagaaga aaaagggctc
      841 tacatactaa ataaagaaga cgtcatgcat gaatcttacc gaatagatgg atagatagac
      901 agaggttgtg aaatcagcgc cttggcttgt tactcaaaac taagcgactt tttcacaacc
      961 tctgatatct aatatacgtt gttccagaag ttgcttcttc gaaaaataag ccaaaattcc
     1021 acaaaaattt aagaagcaat tttcgaaaaa tcctttctta ttttttgaag ttgatcactt
     1081 ctgtcacaac ctctcatgtc acaaaccatt tttttgtttc ctttaactca atataccgta
     1141 cgtcttccca caatatcggc tgatggtcaa tcataaagta atcttcatag gcttcaccaa
     1201 tgaagtgccc ttcgacctca tccaagagtc ttccaaattc atcttttaaa ttgagctgaa
     1261 tgattactgc tttacgagat aaaaaggctt ctgtcagtat actatcgatt tcttgcaatg
     1321 tcatttgttg tttaggaaga ggctgtttgc gtgcttcttc ttcatttttt tgataccgtt
     1381 gactagttct tccatcgcaa aagcagtccc ccattttaat ccaaatggcc gatctcgata
     1441 ctcgttatag tcaatgaatt tttttgctgt ccgtctcatc ttttccacct tctaatccac
     1501 tcataccacc tgcatgcccg ccaacgagag aactacgtgc gatggcgcgt cctccttgca
     1561 agagactatg cgcatggatg attgattgaa agccgtattt ttttctaatc gtatcgacaa
     1621 caaaatcaac tttcgcttca tttatctgct tttcaggatc ttcaaaaagg ttaagctgta
     1681 aacctgtcgc gtatacgagg tcggaacagt tcacgcctac acgccgaata tcctggtagt
     1741 ggtaatgctg gtggaaaatg gtcaataaag catctgcaag atctctgcta gcatttgtcg
     1801 cttcgatttt catttgctgg tgaaacccgg tcttgccatt tggatcaaga tagcctaaag
     1861 agtatcctac ccataagctg actacttgtg tttttgctgc agatcgtctc aagcgagtgc
     1921 cgacttggtc ggccatttct ttgataacga tctcgatttc ttctcgtctt gtataatctc
     1981 tatctaggat ttgactattt ccgatacttt ttgattttgg tgtatattct tgtcccaaaa
     2041 aacttcgatc gatgccccaa gcatgggcat aaagctgagt accgatgacc cctagcttgc
     2101 ttttcaagtg ataataatcc gcgtgagcta aatcataaac agaatgtata cccatttgtt
     2161 tcagacgttt tgctgttcgt ttgccgattc cccaaaagtc agtgatatct gagattttcc
     2221 ataacttttc tggtacatct tcataacgcc attcagcaaa catttgcttt ccgtcttttg
     2281 agccattgtc taaggctagt ttagcaagta gcgggttatc gccaattcct atagtcgtgt
     2341 agattccggt ctgctcaaac acatctttat ggatcagttt agccatgtcg tacgcatttg
     2401 ttttaccaaa gagtgccatg ctatttgtta catcaaggaa gctttcatcg acggaataga
     2461 catgatggtt cgcttcgtct gcatattttt tatagataga attgatttct ctgttctttt
     2521 ccatataata ggccatcctt ggggcaacaa tatataaatc acttggatag gggaagggaa
     2581 gatctctggc acggctgata ttggtgatgc cgtaagcttt ttttgctgca ggactggaag
     2641 ccaagattaa tccgctaccc cgtgtttctg tcgaatcgga cggataggac atgactacta
     2701 atttagttgt aaggggatca agatcctttt caacgcactc tacggaggcg taaaaagatt
     2761 tgcagtcaat acataaaata tctcttgaag gttctttttc ataaacaaat accggatttt
     2821 gattcgccca cataacaatc acctcttcaa cacaattaga acacacgttc tctttccgtg
     2881 tcaataaaaa acagcaattt tcaaatacga gcaaaaggct cacatttgga aattgctgag
     2941 aggttatttt tatctatttg tttttagctg agatcgttga tttttttatc aaacatgaac
     3001 agcttctgga tcgatctttg ttgtcccatt tccaatgtgt gcaacataaa attccggagc
     3061 atagccgaca actttcatgt attcatcata gacattgttt ttgaaggcag gtatattttc
     3121 ttctttgaca agagcaatcg cacagccacc aaatccagct cctgtcattc gtgcacctaa
     3181 gacaccttct tgtttttgag cagcatctac tagtgtatct aattcgatcc cagttacttc
     3241 ataatcatag cgaagagagt ggtgagaatc atttaacagt tgaccaaatg cttctaagtt
     3301 cccagcttct aattcagctt ttgccttcaa agtccgctga ttttcagaaa cggcatggcg
     3361 agctctgcgt atcaatgtat catcgccgat ttggtcaata gttgattcaa attcttcttc
     3421 atctaagtct cctaaagaag agataggcaa agttttttgc aaacgtgcca aggcttcttc
     3481 gcattcgcta cggcgttcat tgtattttga atctgccaat tcccgccgct tattcgtatt
     3541 catgatgacg attgcataac catctagttt cactggaacc atttcgtatt tcagcgtatt
     3601 tgtatctaat aagattgcat gatctagctc accgaagccg atggcaaact gatccatgat
     3661 acctgaattg acaccgatga attcattttc tactttttta cctgtttgga ctagttccaa
     3721 gcgatctgtt tttaaatcaa acagatcttc taatacaaca cctactaata attctaatga
     3781 agcgctactg gaaagtcctg caccattagg gattgttcct tccactaata actcaaaccc
     3841 atgatcgatt gagtgtccag cttcttttaa tttaaggacc attcctttta cgtaatttgc
     3901 ccagtttgct tttttatcat attctagctc atctaaagta aaactaatga caccgatatc
     3961 gtcaaagttt gtggaataaa ctaatatttt attatcgtct cgaggtgctg ctacaccttg
     4021 cgttccataa gtgatggaag cggggaagac atggcctcca ttgtaatctg tgtgttcacc
     4081 aatcaaattg atgcgtcctg gtgagaagta ttgtgtagtt tttttaggtc cgaatgtttc
     4141 ggcaaatttt gtgtttaagc ttcttttgat ttccatgatg agttattcct ttcttgtttt
     4201 gattttgaat tctgttactg tttcaaatac tgatccggct tttaaatgaa tcgaaccaaa
     4261 tgctgagaag cgctctgcac ctggagctgt ttgagtctca aatgtgatgc caccgtgatg
     4321 tgccagtttt cggttgcgca tttctggtgt ttctgtgccg aaatttgcag tgaaaataac
     4381 cacactagaa gcatctgtag caatatctac ttggattctt ttatcggggc tagtcaagcg
     4441 agcggcttct ttacccaagc cggtttcttt taagaaaaat ggatgatcga ttccgtcaac
     4501 aagatttttt tgatccaaat cactagcaaa aacggacgct aattttttag gtatttgaaa
     4561 atcgaaagca cttcctgcag cattttcttt tacccctata ggaatactat ctgttcgcaa
     4621 aggagcataa gcttcgctat tgagccaaag ctcatgttga tcgattgact gagaagcatc
     4681 tcccgtcaag ttgaagtaaa catgatttgt cggattgaat aaagtatctt ggtcactggt
     4741 gccgcgagag gtcactcgcc agatattatc ttttgtcaaa gtatagcgga tttccacatc
     4801 cattgtacct ggaaaaccat gttctccgtc gggacttgta gtagtaaaaa tgacagaagc
     4861 ttcattttcg ccattcaaaa tgacataaga ccattttttt aattcaaatc caggagcacc
     4921 accatgcaga ttatgtccag tttttggatc tgtggctaat tggtaagttt ttccattgag
     4981 agaaaagcgg ccattttcga ttctccctgc ggtgcgaccg atagaagcac cgatatacgg
     5041 atctttttcg atatattctt cagcggtgtc aaatcccaaa actaattctc gatcatttga
     5101 ttttaaactg acgattctag cacctaaatc agagatagaa agtgctagct tgtttttgtt
     5161 ctccaaggtt atcaagtgat aaccttggcc aaaatctttt tctgtaatct tcattttcaa
     5221 gatcctttct taatgggaag gaactactgc atcgtgaagt taatcttcca ttgtatcagc
     5281 tggagccaat ttgttttcca atttctcaac gatttgtgca tgttttttct ctgtcaatgt
     5341 aatcttccaa gcaaaaataa tagcggagaa aatcatcaaa gcagcaggag catagaatgc
     5401 ataagctttg aaagtcgtta cgccatgagc agtgatatca gcagcagtag cattaccagt
     5461 catcccagaa gcgatagcga caaaccctac gatcccgtta gacaaagcac cagcgatttt
     5521 atctagtaaa gggcgaattg atagagtaac agcttcgtta cggataccat ttttccattg
     5581 accatattca acagagtctg tgatcgtcat caaagcggat aagaaaatca attgttgagg
     5641 gaagtagaac aatactagcc cgatgataac gattggcaaa cttgaacctg cgatcgtaaa
     5701 gaaaaagtaa gaagaaatca tcattgcgat ccctccaagg taaacgtagc gacgagagat
     5761 gacgcgtgta agcattggga atagtggaac agctactaaa ccaagtaagg cagcaactag
     5821 accaacgatc caaaattcag ttggttggcc aagtacatat ttgaagaagt agaataatac
     5881 ggcagttgtt gctgcattgg caatcgcata agcgatataa gcaagggcaa gccacatcaa
     5941 ctgatcattt tgagcaactg ctttgaacac atctttgatc ccagcttttt cattttgctg
     6001 acggatcgca gtatcgactt cttttgtgcc caaggcagtg ataatcgcag taccgcctga
     6061 aataacagca gcaatcacac cgaaccagaa ccagcctgaa gcgccttcaa tatgtttatg
     6121 agtaacaaga taggtaaaga aagtaacgat agggacaacg actagagtag taccatttgc
     6181 acctagagaa gagccgaaac gagcaaacgt agcaaatttt tcacgttcct ttgtttccgt
     6241 actcaaagct ggaatcattg accaaaaagc gatatcctta aatgaataaa aactatccaa
     6301 taagatgaaa acgattgcaa ataatatgat aaataaagtc gtattatgag tagctaagcc
     6361 aaagaaattg gtaaagattg ctaccaagag tacggaacta acaacgccgc cgataactaa
     6421 ccatggtttg aatttaccgt attttgtacg agtattatcg atgatgccac caatcaaagg
     6481 atcaaaaata atttcaacta agcggatacc tacaactaag cttgtaactg tagcaatcat
     6541 ttttgcattc gttgccttat ctgttcctgc gaacatctgg cttgtcacga ataccataaa
     6601 ataagtgctt aatgtaacat agaatgtgtc gtgtccaaaa gcgcctaaag cgtaggacac
     6661 acgttggatc attttgcttt tcataatctg tattcctctc ctgttcaata tataatacta
     6721 agtaaaccgg ttacaacgaa taacaaagat cttttaatga cttaaactta acaagaaatc
     6781 gcttcctttt taatatattt ctgtgacttt tatttaactt tttgttgcat tatactaaag
     6841 gagtaaggag ggatagacgt ggagcaatcg atttttttaa aaaaggaaca tcaacaagta
     6901 gaaaaagaat tgtattttga tttttgtggt ttctctaaaa cgatgccgtt tcattctttt
     6961 ggtcctgcta ttcgcaatga ttacatcctg catgtcgtga tggaaggcaa aggatcttat
     7021 catgtgaaaa atcaacaatt ccaattgaaa aaaggtgatc tgttcttgat tcgtccagga
     7081 gactcgacgt tttacttatc agatggagaa gatccgtgga tgtattgctg gctttcattt
     7141 ggtgggagtg ctgcagaaga aatcattcgg cagtcgcttt tcagagaaga ccaatacacg
     7201 atggtctctt ctgacataca aaaatatatc gacattattt tagaatgcat gaaagatacg
     7261 gaagaaacct tggaaaatga attacagtta acagcattaa cctaccgttt tttatcagtc
     7321 cttttaaaag atggcggaaa ggtcagcggt ggtgtacaaa aggttcattc ctctttagct
     7381 gttgaaacag tcaaatacat cgaggcacat tatgctgaaa aattgtctgt tgaggaaatc
     7441 gcccagcatt tagcggtcaa tcggagccat ttgtcgcgag tattcaaaaa tcatatgggt
     7501 accagtatca aggaatattt gatcggggta cggatcaatc gaggggcgtt tcttctttct
     7561 ctgacggatg aatccgtgga aagtattgcc tatcaagtag ggttcaatag tctagtcgta
     7621 tttagccgaa tgttcaaaaa gagtaccgga gaaacggcta cgaactatcg taaacgtatg
     7681 aaaaacgaaa attttaagaa tattgctttg gataccttga aaaaacagtt ggaaaaacaa
     7741 accgcagttt cttggacaac ctgattagtc tggttaaaat gacaagcatc ggcaaaagaa
     7801 acttgtggcg gttatgctac actgtaaagc gaagactaaa aaggaggaaa agggatgcgt
     7861 acacttatca tcattagcca tccaacgatc gaagaatctt taaatcagca atttttcaaa
     7921 gaagcttctg ctggtttacc agctacttgg catcatttgg aatcaagtta tccagacgga
     7981 aaaatagata tagagactga actacagctc ttggcccagc atgatcggat cattttccag
     8041 tttccgtttt actggtatag ttctcctgct catttaaaaa tttggcaaga taatgtcttg
     8101 gaacgagcag cacatgtatt aaaagggaaa gaactaggaa tcgtattgac aacaggtgtg
     8161 gcggaaaaag aataccaagc tggaggaaaa gaagaatata cgatttccga atttttgagg
     8221 ccgtatcagc gaatcgcaaa taaattccat atgacctatc ttccgccatt cgttttagca
     8281 caatttatgt atttatccca ggaaaaacgt tgggagaagc taattgctta tcagcagtat
     8341 ctctcattgg aaggcaaacc atcgctgact cagcggattg actggtttat tcaaagagta
     8401 caggaaaatc agaaaatgca ggaagaagaa tctgaaaaac aagcatatat cgtagaagca
     8461 ctgactgagg caaaagagca gatcgaagac ttgaccttta cactgcaaga aatgaaagga
     8521 acttcattat gacaaatgat tggctgatcc aacaattaga tgaattaagc gaaaaatcag
     8581 aatatcaaga ccgtgcgctc ttatatgaaa taaagaaact gatggctgag atagacgaac
     8641 gaacaatgca gctgcaagga gaaatcgacg gacaatcttg gaatcatctc aactggtgaa
     8701 attttcttat aaataacaaa gataaaaatg tgcacagcga caattatttg ctacaataag
     8761 aatatgaagc gtttgataac gctattatac ataaaaattg gtggtgaaaa aaatgtatga
     8821 tgaaaatgag tggggagaaa atgttcggat gacccgaaga agacagcaaa aacaggcagc
     8881 tcgtaagcgg atgatcatga ttggggcagc agttgccgtg tttttgatca tagcaggagg
     8941 agttgcgggt ctatattttc atggaaaaaa ttcgtcagaa gcgaaaagta cgaccataac
     9001 ggaaacaacg acaaagaaaa cagagacgaa acaaacaagt gagtcatcaa ctaaaacaaa
     9061 agagacacaa acttctgaag aaaaaacagc aaatggtttg ccagagcaac ttcaagcaat
     9121 cgtaaatgat tattcgaaaa agatcgaaga aaagacgcct gcattgattg aagaatacca
     9181 gacagaaatt cagggaaatc aagagggaat agctggttta tcagcagttg ctaaccaaaa
     9241 agcacgtgag cttcaagcaa tctccgacga agggatcaga aaattacgtg cagcgtatca
     9301 ggcagcagaa aataaagacg gtgtagactt agatactttg atcaatcaat tatcggctaa
     9361 ttatacgaat catgtcgcta agatttccga tatttatttg cagactagcg cctctcttca
     9421 agcagagtca acaagcacac aagacacaac atcttctgat tctgagacag cagagtcggt
     9481 agaagcttct gaaatgcaag ctcgaacaac acaagacaca acagattcct ctgaaactaa
     9541 taccaacagc gcgacttcac aggctgcgac aaccgtagtt ttggaaggag aaggtccaaa
     9601 tcaaatagcc gaacgaactg gcgtaccagt agaaacgatc ttgtcgctga atgggatgag
     9661 catggagaat tatttcctga ctcccggtga gacgctaaaa ttgaattgat aaaagcaata
     9721 aaaaagaacg aagcttccac taaggtgaag cttcgttctt tttttatttt ccggttcttt
     9781 tttcgcgtac aaagtaatgg atcgtcatgt aaagcaagaa aacgagtcca ataatcaatg
     9841 agattctcgt ttcaggattg ataaacatga aaatcaatac gatagctaaa aaagcaagtg
     9901 tcacataatt cgtataagga gatagtggca ttttaaaagg atgatcatgc attttatctg
     9961 cgtgcttctt tttgaagcga atctcgctga tcaaaatcac tacccaagga accataccag
    10021 gcaaaatact tgagctgtat acgaaaacga aaatattttc tgactggttg atgaacattg
    10081 gtagaagata atttaagatc agaccaatta agattccacc tgagattgct acgacaggat
    10141 aaaaaggcgc accgtgacga gatagtttca gaaatttttt agacatcttt ccatttatgg
    10201 caagtgtata gaccatacga cttgcgctga aaatccctga attgcaacct gataatgccg
    10261 ctgtaatcac gacaaaatta atcagtcctg cagcaaatgt aatgccgact ttagaaaaag
    10321 tttgtacaaa aggtgaacca atctcactca attgattcca cggatagata ctcacaatga
    10381 taaaaatagc accaatataa aaaatcaaga ttcgaccgat agtggactgg acagcttcaa
    10441 tgatcgtctt tttaggattc tctgcttcac cagcagtcat tccgatcagt tcgattcctt
    10501 gataggaagc aacaacgatc gataatgcaa agaaaaatcc tttgacgcct ccagtgaaga
    10561 atccaccatt tttccaaaga tttgaaatcc ctactgcctg accatgatta ccaaatccaa
    10621 ataagattac cccaagacct gcaatgatca tcaaaatgat cgttatgact ttgatgatcg
    10681 aaaaccaaaa ttctaattcg ccaaacgcct tgacagaaat aagatttgcc agcataagaa
    10741 acaagacgac aatgattccg ggaataattg ccggcaaatc aggccaccaa taattcatat
    10801 aagatcctac agcaatcact tcacttattc ctacgacaat atattgaaaa atattactcc
    10861 aagcggtcaa gtagccagcc acaggatgga tgtactcgct cgcgtaattt gcaaaagaac
    10921 cagtcgaagg atcaacgtaa agcatttcgc ctaaagcacg cataatcaaa tacaaaaaga
    10981 atcctgcaat cgcataggct cccatcactg agggccctgt ccaacgtatg gttgaggagg
    11041 cacccataaa cagaccgaca ccgatcgttc cacctagtgc gatcatttgg atatgacggg
    11101 cactaagact tcgagttaac ttttcttctt ccatacaaaa actcctttcg ttgttgagtc
    11161 aacaagaaaa aataatcaaa cgtttcaaca catgtttttc attattaggt tagccttatt
    11221 gaactcttga tgtgattcta cagaaaattt tcataaaatg cgaggaaaat tcgaaaaaaa
    11281 ctttttcatc attctacttg aaaatgcttt ccattttagt taaactatat ttaaataaaa
    11341 agttaggtaa acctaaaaag gagtgtaaga tttggaacgt acggccattg taattcaaga
    11401 cctttcagcc gcttatcaag ggaaaactgt tttgaaaact atcaacttga cgataaatcc
    11461 acaaaaaatt accggtatta tcggaccaaa cggtgcagga aaatcaacat ttatgaaatc
    11521 tttgctagag ttgataccag ctactactgg taaagtcacc ttttctggac agtcggtaaa
    11581 ctcagtccgt aaaaaaatag cctacgtgga acagcgaagt gaattggatc tttcctttcc
    11641 aattgatgta ttaggcgttg tacttttagg aacatatcca tctttacgaa ttggacaaag
    11701 acctgggaaa aaagaaaaag aacgtgcaag acaagctttg aaaaaagtag ggatggaaga
    11761 atatgccaaa agacagatca gcgaactatc gggtggacag cttcagagag tttttattgc
    11821 aagagctcta gcccaaggag cagaatggat ctttttagat gaaccattcg tagggattga
    11881 tgcgttaagt gaacgaaaga tctttgacat cttgcaggaa ttgaagaatt caggaaaaac
    11941 gattttgatc gtccatcatg atcttcataa agtagaagaa tatttcgatg aggttattct
    12001 tttaaataaa cagctgatcg cttccggtcc agtacaagaa gtctttacat cgaagaacct
    12061 tcaattggcc tatggtgaga tcatcagaca tttagtaaaa ggaggagaga aaaaatgatc
    12121 caatccttta ttgatggatt aatgaattat caattcctgc aatacgcttt ggtcacttcc
    12181 atgcttgtag gacttgcttc tggagtcatc ggttctttta ttattttacg agggatgtct
    12241 ttgatgggag acgctatctc tcacgcagtt cttccaggtg tagccatttc ttatatgttt
    12301 ggttttagtt acatctttgg agccactgct tttgggatgc taacagcagc agtgattggt
    12361 ttcgtgactc agcggagccg attgaaaaat gatacagcga ttggaattgt ctttagctcc
    12421 ttttttgcat tagggattat cttgatttca tatgcccaga gtgcgacaga tttgtatcat
    12481 attttatttg ggaatgtctt agctgttagg gaaagcgatt tgttgctgac agcactcgtt
    12541 agtggaatcg tcttgatatt tgtctttttc ttttataaag aattgaagat cacatcattc
    12601 gatccgacaa tggcaaaagc ttatgggctg aacacatcgc tgatccatta tcttttgatg
    12661 ttctttttga cattagtggc tgtagtcagt ttacagacag taggaacaat cttggtgatt
    12721 gccatgttga tcacaccagc cgccacggct tacttgctaa cgaaccattt actgaaaatg
    12781 atcattacag ctgcaggaat cggtatgcta agtgcagttg tcggtgtgtt tttcagttat
    12841 agttacaatt ggccatcagg agctacgatc gtgttagcat gtaccgcatt ttttatcctt
    12901 gcttttttat tttctccaac aaaaggaatt ttatttcaga aaggaagcag atagatgaaa
    12961 acaaaaaaat cactcttttt aatcttggca gttagtttct tggtattagc cggttgcgga
    13021 aagcaggctt ctgaccaagc ggatgaagga agtaaagaaa agttgtcagt cgtggctacc
    13081 aattcgatct tggcggacat ggcaaaagag gtcggaacag atcaaataga tatccacagt
    13141 atcgtaccag tcggaacaga tccgcatgaa tatgaagtac taccagaaga catcaaaaag
    13201 gcaagcgatg cagatgttat tttatacaac ggtttgaatc ttgaaacagg taacagctgg
    13261 ttcgataact tgatggaaac ggctaaaaaa gaagaaggaa aagattattt tgcagttagc
    13321 aaaaatgtag aacctcttta tttaactagc ggtgaagaac atacaaaagc agatccccat
    13381 gcttggctag acctatctaa cggaataaaa tatgtggagg aaatcgcacg tatattctct
    13441 gaaaaagatg cagaaaatgc gacactctat aaaaaaaatg cagaagcata tgtggaaaaa
    13501 ctaaaagaat tagatacaca agcgaaggaa agttttgctt ctatcgaaga gaacaaaaaa
    13561 ttattagtaa caagtgaagg ggcattcaag tatttttcac gagcatatga tttgccagca
    13621 gcttatatat gggagatcaa tacagaaagt caaggtacgc ctgatcaaat gaaagcgatc
    13681 attgatcaga taagagcaaa agaagtaccg gttttattcg tggaaaccag tgtagactca
    13741 agaagcatgg aacgggtagc aaaagaaacg ggtttgaaaa tctatgataa actgttcact
    13801 gattccatag caaaagaagg agaacaagga gattcttact atcagatgat gaaatggaat
    13861 attgaaacga tccatgaagg tttgtcacaa acaaaagaaa gctgaaaagt gcaaggtcta
    13921 gcttgaggag cagaccttgc attttttata agagatatga aaaaaaatta tgctgttttt
    13981 cgtcgtacag ataccttttt tgaagaaatt ccgttatagt tagagtaagg aaggaaggtg
    14041 tggctatgaa ttttacacgt aaagataaat atacgattaa agaagaagtc tttcgattga
    14101 tcagccagca ggaaaatacc gacaaggatc aagaccttca atttcttgaa gcagaattag
    14161 ctaaattatt catagcaaat caaaatgaga caacagaacc agatgaagag ctgtacatag
    14221 gcaaatggtt gtttgatgaa tttcagcctt tagatgaaaa taccggtatc ggttattttg
    14281 tgttcctttc tccagtcggc ttcacacctg gcgtattagt taaacaaaac gacgaaataa
    14341 ccgtcaaagc atggcctgca ttattttcag tcatcaaagc agaaggagta atcaaaaaga
    14401 tccagtcggc ctattataaa agtcaattta ttgccaacag caaattaatg aatatgtttt
    14461 ataatcgtct agtagaaatt gctaggcctg ggaaaatccc gcaaacattc acgtacacac
    14521 agcaaaaaaa tctctatgaa gaagtattgt attcccgcga tctgtctgag ttttcgccat
    14581 gggaagaggt aaggctccat gaactgttaa gtacaaaacc agtttcattg aattttttta
    14641 atgcattaga taacaaaaga aaattaattt caacaaatta ttgggaagta tttgctgcaa
    14701 gaaaaaaatg gatggaagaa aagaagattg ccgatcagca gatccagttt gtccagctga
    14761 aaaaagaaaa actatattat gggttataca gccgttaaca gcaagcgagg aagaccatga
    14821 cattaaaaga agaaatcata caagaaagca aacgattagg aattgacaaa atcgggttca
    14881 ccacggcgga accttttgat tcattaaaag aatcgttgga agaacaaaaa gcagctggcc
    14941 atacttctgg ctttgaacat ccaaatatcg atgagcgtct ttatccagaa atgacatttg
    15001 atcagccgaa atcgatcatt tccattgcac ttgcgtatcc tactaggatc catgaagaag
    15061 tgcctaggga tgaaaaacgc gggcagtttg ctcgtgcttc ttgggggatc gattaccatg
    15121 atatactcag agaccgtttg aaccgattga tcgaattcat ccaaacaaga gcagaaaaat
    15181 ggcaaaaaga agaggaatgg cgtctagctc cgcaagtaga tactggagaa ctgatcgatg
    15241 tcgctgtagc acagcgagct ggtttaggat ttattggacg aaacggattg ttgatcactg
    15301 aagagttcgg ttcatttgtc tatcttggtg agatcgttac taatattgta tttgagcctg
    15361 ataaaccagg agaatttggt tgcggtgact gtatgcgctg cgtgactgct tgtccgacaa
    15421 aagcattgct tggtgacgga agaatgaatg cccagcgatg tttgtcttat caaactcaga
    15481 caaaagggat gatgccggaa gaatatcgta aaaaaatgcg aaatgtcatt tatggatgtg
    15541 atatctgcca gttagtctgc ccttacaatc aaggaaaaga ttttcatttt catgaagaga
    15601 tggaaccaaa agtagacgaa atatatccaa aattaaagcc aatgctttcg atgtctaata
    15661 aagacttcaa acagcaattt gggcatttag ctggttcatg gcgtgggaag aaacctttgc
    15721 agagaaacgc attgattgct ttagctaatc taggtgatcg aacggcattg cctgagattt
    15781 cagaatgttt aacagatgtc cgccctgtca tcagaggaac agcagcttgg gctattggac
    15841 gtctaggaac aaaagaaccg gaaaaatggc ttgatgtatt agatgaaata ttagctaaag
    15901 aaacagaaga agtcgttata aacgaattgg aacatgccca gaaattattg cggagaaagt
    15961 taaaataaaa aaatagttaa cattattca
//
LOCUS       DAFLWQ010000066        15509 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.069, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000066 DAFLWQ010000000
VERSION     DAFLWQ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.069"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(224..454)
                     /locus_tag="L1V16_002079"
     CDS             complement(224..454)
                     /locus_tag="L1V16_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276410.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(890..1456)
                     /locus_tag="L1V16_002080"
     CDS             complement(890..1456)
                     /locus_tag="L1V16_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBN1276411.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1456..2412)
                     /locus_tag="L1V16_002081"
     CDS             complement(1456..2412)
                     /locus_tag="L1V16_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBN1276412.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICNQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2412..3068)
                     /locus_tag="L1V16_002082"
     CDS             complement(2412..3068)
                     /locus_tag="L1V16_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBN1276413.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3438..5456
                     /locus_tag="L1V16_002083"
     CDS             3438..5456
                     /locus_tag="L1V16_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBN1276414.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5526..5732
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5883..8297
                     /locus_tag="L1V16_002084"
     CDS             5883..8297
                     /locus_tag="L1V16_002084"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBN1276415.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8645..10198
                     /locus_tag="L1V16_002085"
     CDS             8645..10198
                     /locus_tag="L1V16_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBN1276416.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10579..12363)
                     /locus_tag="L1V16_002086"
     CDS             complement(10579..12363)
                     /locus_tag="L1V16_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1276417.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12378..14099)
                     /locus_tag="L1V16_002087"
     CDS             complement(12378..14099)
                     /locus_tag="L1V16_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1276418.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            14199..14960
                     /locus_tag="L1V16_002088"
     CDS             14199..14960
                     /locus_tag="L1V16_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1276419.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         5061 a         2835 c         3025 g         4588 t
ORIGIN      
        1 tcagtcacga tatcaaacaa aaaatatacg tctttcttca ttctagtttt cgcagcaggg
       61 attttaaagt agttcttatt agaatagtag agattaatta ataagctatc ttcgattgct
      121 aaaaagaaaa cttctgaatc ccacacctta taaaaatctt tgacaaatct attcgaagga
      181 tcaaatttaa accataattg cgtctcatta aaaagcataa ccattactcc gatctatttt
      241 taaacttagt ctctacctct aatatatatc gagtttttat tttgccttca gagaatactg
      301 tttctttttt tgcagttaca ggttgtttat tttcggaaaa agctaatata gctaaaattg
      361 aaacatccat ctggaattta tcttttttac tgctttgatc ataaaagtct gcatattcat
      421 cactgatatt ttttctaata aattcttcca tcataaaaat cacctcaaaa cgattatacg
      481 aacttacgtt cttgttgtaa agcgatattt gaggggcaaa aaaggggcat aatttgactg
      541 atattaagtt agctattgat atatgaatga catacaaaaa tataaaatct tttaaaaatg
      601 cttatatatc aatgtttttg ccattctttt atatatctgt tatatgtcaa aaaaatgtgt
      661 tcaatttcaa tttgtatttg aataaagagg ttgtgaaaaa gctgtcctgc atcaagtaat
      721 aagaacagcc aatcaaaaac agcttctcat gtttttgatt tggttggact tattaccgca
      781 gatataagct tttgagcacc gtgaataaag aggttatgaa atcaacgctc taacctgagt
      841 attagagaaa aaaacgcaaa acatatcatt tatgttttgc gttttttatt tatctttttt
      901 tctcaataca atataaaata ggcggctggt tcttttggtt gataaaccga taattcagca
      961 cattatatgt ttcctgtggc agtttggaac aaaaagaatc aaccatatcc agttcttttt
     1021 ctccaccttc atgaccatag tagacgacaa ggatcaatcg tccgcgaggc acaagtcgtt
     1081 tcaatatttc ttccatagct gtgcgtgtag tctctggcat agtgatgatt gctttatcac
     1141 tttttgggag ataccctaga ttgaaaatcc ctgctttgag attttgttgt tcagctatca
     1201 cttctcctaa cgtttcgtgg ccttgtagaa acaatgagac acgttcttct aactgacgct
     1261 gttctagcct ttcacgagta gcatcgattg cttgttgctg gatatcaaaa ctatagacat
     1321 gaccagtttt tccgatgtgt tctgctagaa aaaccgtatc gtggccattg cccatcgttg
     1381 catctacgac gtgatcccct ggttgcaaga tttcttgcag taatgtatgg ctgaaatgca
     1441 aagcagtttg caacatcaga cgctcacctt tttccgtaca tcatattttc cttggaagct
     1501 atctctgcga agaagttctt catcaattgc attcaagact tcccattttt tcaagctcca
     1561 cattggtcca atcaaggaat cccacggcgc atcccctgtc aaacgatgga tgatgatctc
     1621 ttttggtatc atttccagct ggttgcaaat gacattgaca tagtcaggac ggctcattaa
     1681 ttgaaggcga ccttcatgat agtcccgcaa cattctcgtt ttgcgcatca gatgcatcaa
     1741 atggagcttg attccttgga tatctgaatc taaaatggtg cgtctgacat tttctttcat
     1801 catttctaaa ctttcgcctg gtaatccgtt gatcaaatgc gtacaaacac ggatattatg
     1861 tttgcgtaat ttagccacgc catctaaata agtttgataa tcatgtgctc ggttgatcag
     1921 ttttgaagtt tcttcaaaag ttgtttgcaa tccaagttct acccataaat acatccgctc
     1981 gttcagttca gcaaggtaat caactacttc atctggcaga caatccggtc gtgtaccgac
     2041 tgataatcct acgacacctg gtaaattgac tacttgctca aatcgttctt tgattatttc
     2101 aactggcgca tgggtgtttg taaaattttg gaaataaacg atgtattgtt ggacatgagg
     2161 ccatttttga tgcatcatgt cgatttcttt ctggaattgg attggaagag ggtcttcagg
     2221 tgcaacgatc atgtctcccg aaccagatac actgcaaaaa gtacaaccgc catgggcaac
     2281 agtcccatct cgattcggac agtcaaatcc tccatcgatc ggcaccttga aaattttccc
     2341 gccaaactca tttcgtaaag cgtaattcca agaatgatat cttttatttc cttctgaata
     2401 aggaaaagtc attaaaagtc cttctttctg taagagttat ctatttgttt tcttttttct
     2461 ctatacactg gataagtcag gcacagccaa gaaagactga gtaagtagcc gccgatgata
     2521 tcagtaggaa aatgaacgcc cagataaatg cggcttatcc cgacacttac tataataaac
     2581 atcatcagca attgaagcaa tgtgcgtaag gttctttttt gaacaaaagc tggaagcaga
     2641 aatagtaaag aaccgtaaag aatcatactg cctgctgcat gtccactagg gaaactgtaa
     2701 cttgtttcaa ctactaagtg cgccaatgaa ggacgctctc gcatgaaaaa tagtttgatc
     2761 accgggttga tgattccagc aattacaata aatccagaaa cgaaccaaaa tgtttctgcc
     2821 ctttttttct tataccacat ccataaagcc gcacaagcaa ataaaatgat gacggtaaga
     2881 ggattaccga atttagtcat aaagagttgg tagctgttca gatcaggata agaagctctg
     2941 acaatgcctg taaaccactg atcgaaacca gaaagccacg acagatggaa ctttacgatc
     3001 cagcccaaaa tgaaaaacag gacaagaaag aagctaccag ccacctgaaa tgatgtttta
     3061 tatttcatac aattcctcct ttgaagcaat gacttattat agcatttttg gtccagcgaa
     3121 aaaaacggta aagagataaa accaatgtat gattcctctt tgaataacca atattcttat
     3181 aaaaaaaata actgtaatcg gaaagacatt ttttggtaat gcaaatgaaa tgttagggaa
     3241 ataaaatcag tgtttttcga aatcctttta aacaagaacg tagacgtagg aagaacttga
     3301 aaatgaacag aagttgttca ttacggtaaa ttacaatatg attacaaaaa acaacaaagc
     3361 tcttaaataa cttttaataa atattaagag aagttataat tattaataat agataaattg
     3421 aagttggagg atagaagatg gaaaacattg caagaaaaga acggagacgt ttagaacaga
     3481 ccaaacgttt tcgaaaagca aaacgagggg cagcaatcgt gggaactgcg atggtaggct
     3541 gttctgtcgc tgccccatta gtacagccgg ttcctgttca agcggatgaa acacctgttc
     3601 agttcggcgc aagaatcaat acagcggcat ttatcacaga aattgctact tatgctcaac
     3661 caatcgctca agccaacgat ctatatgcat cagtgatgat cgcacaagca gttgtagaaa
     3721 gcggttgggg cagtagtgcg ttatctcaag caccttatta taatcttttt gggataaaag
     3781 gcagctatca aggacaaacc gtctacatgg atacgcttga atttttaaat aatcaatggg
     3841 taaataaaaa ggagcctttc cgacaatatc cttcttttgc tgaatctttc aatgacaatg
     3901 cctatgtact tagaaatact tcatttggca acggttatta ctatgccggt acttggaaga
     3961 gcaacacgaa atcctataca gatgcgacag cttgtttgac agggcgttat gcgactgatc
     4021 ctggttacgc aggcaaatta aataatatca tcgcaactta cggattgacc caatatgata
     4081 caccagctag cggaaacgca ggcggtggag cgactacagg tggcaataat actggaagtg
     4141 caggtagtac tggcggttca agcaattctg gtaatacaaa ctcaggttca gcaacttcga
     4201 ccacttatac tgtccaatct ggtgattctg tttggggaat ctcaaataaa ttcggtatca
     4261 caatggatca attgatccaa tggaacaaca tccaaaacaa tttcatttat ccaggacaaa
     4321 aactgacaat caaaggtagc caggaaaatg gctcttcgac gaataattcc ggtaacaata
     4381 ccaactcttc aggaaatgct ggtacatcaa acggaggaca aacaactggt gcgaaataca
     4441 ctgttcaatc tggtgattct gtttggaaga tctcaaatga tcacggaatt acgatggctc
     4501 aattgattga atggaacaat atcaagaaca atttcgttta tccaggacaa cagctaatcg
     4561 tatcaaatgg cggttcttct aatgctggag caaatactgg ctcaaatact gggaatacaa
     4621 gtggctctag ttcgtccagc tcaagttctt ctaatacagc ttcaggaacg aaatatacag
     4681 ttaaagccgg agactctgtt tggagcgtct caaataaata cggaattacg atggctcagc
     4741 taatccaatg gaacaatatc caaaataact ttatctaccc aggacaacaa ctgactgttt
     4801 caaacagtgg atcaacaaac agcacgtcag gtaatacagg ttcgtcaacc aatacaaata
     4861 acagcagttc agttaatact ggcagcagtt cgtctcaagg cacttatacc gtgaaagcag
     4921 gtgaatctgt ttggagcgtg gcaaataaaa acggcatcac gatggatcag ttaatcgaat
     4981 ggaataatat caaaaacaac ttcatttatc caggacagca attgatcgtt aaaggtggaa
     5041 cttcggcaaa tacaaataca ggttcaacta cttctgcagc gaaaccaaat acaccgaata
     5101 cgtctgctac gacaagtaca tcatccactg gtaatacgat gtataccgtg aaagcgggcg
     5161 agtcagtttg gagcgtagcg aacaaacatc atatcacgat ggatcagtta atcgaatgga
     5221 ataatatcaa aaataatttc atctatccag gacagcaagt gattgtgaag aaaggttcat
     5281 ctcaatcaac aaaccaacaa tcagttactg gttcgaaaac ctatactgtg aaatctggag
     5341 aatctgtttg gagtgttgct gacagtcatg gaattacaat ggctcaacta atcgaatgga
     5401 acaatattaa gaacaacttt atttatccag gtcaaacgtt gattgtagct aaataaaata
     5461 gctgttcgaa gaaataacga ttgaattcca caaaaatatt tgttactata aggctactta
     5521 aatatgacaa cacttgaaaa ggaagtagta aaaagactga agtttcagag agcgcatggc
     5581 tggtgagaat gtgcacggat gcttttgaac tcgcctttga gttgcccttg ctgaataccc
     5641 gagtaagcaa gcggcggtga cggccgttac aacgttcgag gccttttcac taaggtaaaa
     5701 ttaggtggta ccgcgtagat tacgtcctat aaaaagagca atctttttat aggatttttt
     5761 tatttctttt gtgaagtttg agaaaacaaa gcaaaaggaa ataaaaataa acagattctg
     5821 ccggtttttt cgttatattt ataatagaaa caagtgtttt caatagaaca ggaggacagc
     5881 aaatgagtta caatcataaa gaaattgaga aaaaatggca aaaatactgg gcaaaaacga
     5941 atactttcaa cacccatgat gatcctgaaa agccaaaatt ttacgcactg gatatgtttc
     6001 cctatccatc cggtcaaggg ctacatgtag ggcatcctga aggttatacg gcaacggata
     6061 tcctttcacg tgtgaaaaga agtcaaggat acaacgtgct gcatccaatg gggtgggatg
     6121 cattcggtct gcctgctgaa caatatgcgc tagatacagg aaacgatcca gctgagttta
     6181 cccaaaaaaa tatcgaaaca ttccgacgcc aaatcaattc tttaggattt agttatgact
     6241 ggaatcgcga agtgaataca actgatccgg agtattataa atggacacaa tggatcttta
     6301 cgaagcttta tgaaaaaggt ctagcttatg aagcagaagt agcggtaaac tgggtacctg
     6361 aattaggaac agttatttca aatgaagaag tgatcgatgg gaaaagtgaa cgtggtggct
     6421 atgatgtagt cagaaaacca atgcgccaat ggatgctgaa aatcactgct tatgctgatc
     6481 gcttattgga tgatctagaa ttagttgatt ggccagaaag cattaaagaa atgcaaagaa
     6541 attggatcgg tcgttcagta ggagcaaata ttgaatttaa agtggctggt acggataaat
     6601 cctataccgt atttacgaca cgaccagata ctctattcgg tgcaacttac tcggttcttg
     6661 cacctgaact agatcttgtt agagaaatta cgacccctga acaaaaagct gctgtagaag
     6721 cttatatcga agagacagct aaaaaatcag atctaaagag aacggatctt gcaaaagaaa
     6781 aaacaggagt atttactggt gcttatgcaa tcaatccagt taatggcaag gaaatcccaa
     6841 tctggatcgc cgattatgta ttatcttcat acggcacagg agccatcatg gctgttccag
     6901 cacatgatga acgtgacttt gaattcgctc aaactttcgg actagaaatt cttccagtta
     6961 tcgaaggtgg agatgttgaa aaagctgctt acacagaaga tggtacgcac atcaactctg
     7021 aatttctaga cggcatgaac aaacaagaag caatcgataa aatgaatgaa tggctagaag
     7081 aaaatggcgt agggaaaaaa gaagtcagct atcgcttacg tgactggcta ttctcccgtc
     7141 aacgttactg gggtgaacca atcccaatca tccattggga ggacggaaca gtcacagctg
     7201 tcccagaaga agagctacca ttacggttgc ctaagacaaa aaacatcaag ccaagcggta
     7261 ctggagaatc tccattagca aatatcgagg agtgggtcaa tgtcgttgat cctgtaacag
     7321 gtaaaaaagg ccgtcgcgaa acgaatacaa tgccacaatg ggcaggaagc tcatggtatt
     7381 acctgcgtta tatcgaccct cataacaaaa aagaactagc agattatgaa aagttgaagc
     7441 gttggctacc agttgacatc tacattggtg gagcagaaca tgcggtactt catttactat
     7501 atgcacgatt ctggcataaa ttcttatacg atatcggtgt tgttcctaca aaagaaccat
     7561 tccaaaaact atacaatcaa ggaatgatct taggcgaaaa caacgaaaaa atgtcaaaat
     7621 ctcgtggtaa tgtagtcaat cctgatgatg tggtcgaaac ttacggtgca gatacactgc
     7681 gcatgtacga aatgttcatg gggccattag atgcttcgat tgcttggagc gaaaatggct
     7741 tagaaggaag ccgtaaattc ttggatcgtg tatggcgttt gatcgttgat gagaacaata
     7801 aaatgcgtga ccgtatcact acattgaatg atggcaagct tgataaagtg tatcatcaaa
     7861 cagtgaaaaa agtgacagaa gactatgaaa atcttcattt caatacagca atctcccaat
     7921 tgatggtctt tatcaatgaa gcctataaag tggacgctct gccttatgaa tatatcgaag
     7981 gatttgttca actactcgca ccgattgctc ctcacatggg tgaagaacta tgggcaatcc
     8041 ttggaaatga tggtggtatt tcttacgcac catggccaac atacgatgaa gcagcacttg
     8101 ttgaagacga agtagaagtt gttttccaag taaacggtaa agttcgtgcg aaaagcaatg
     8161 ttccccgaga cttaggaaaa gatgagctag aaaaagcagc attagccaat gaaatagtgc
     8221 aagaatatat tgaaggcaaa acagtcagaa aagttattgc ggtaccaaac aagttagtca
     8281 atatcgttgc taattaattg gctctttgtc aataaggact gatgagttgt gcaaaatcaa
     8341 atctgggcca gaatgaactt cattctgtct cagatttttt gttatttcaa attgattaat
     8401 tgattgatca aaaaggtttt gattttcatg ttctcaaaca cgttcaatgt ctttttcttc
     8461 tgaatggtct tgtaagagat ctctgtaatc atcaaatttt tgtctattaa tcttagtatt
     8521 ttttgatgta taaactacct gaaattgaga gtacatacca aattcataaa ttttttatta
     8581 gtgggactag tgattgtatg gattttgacg cataatgaat gaagtatgag aaaaggagag
     8641 acaaatggat caagaactat ttattatcga agtattatca gctaaacaaa aaattatcga
     8701 gaaagcgaaa aaaagagcga aaagaataat gttcaagctt ttaagcttag tatttttctc
     8761 tggtttgctt tttttcggag ctgtatcgtt cctatatcgc catatgagtg cagtagtccg
     8821 ttcagctgaa gggatgcaaa aattaaataa tttgtatcac ttttcgtggg gagttggcgg
     8881 aataacaatt gttgtgctta ttgtttttct tctacttatt tggctccgtt accatcaatt
     8941 gtcgcgtcat ttcgatcaat ggcttagtca aagagcacaa cagtttttac ataataaacc
     9001 aacttctcaa gatgatgact atctttattt tgagaagact tcgacgagtc aagcttttcg
     9061 gatacaaaaa agtgattgcc agttattgct gagatcactt gatgatttac ctatctactt
     9121 aggcgaaagc aaatcaaaat tcggaatgaa cacattccat atttttttac tagaaaacga
     9181 acccagatgg gaaaaaagcc agtcttcgcc tggtggatac ctgacaacta agatgagtac
     9241 attagtcact ggttttttcc tcattctttt agctggaaca atctattatg ggagatacac
     9301 tcagccaaaa atgtcttctc atataaatgc tgcttctcac atgacaatga actcaactaa
     9361 cgatacgcat atacaaaaga caaatgaagg gttgttagct gatcctaagc aaaaggtaaa
     9421 tttgacaaca caaaagataa atgatctcaa acttgataca gagacgcact ctctctatat
     9481 gacaacagat agtggtgcta attgggtatt tgtgccgatt gattcgcaat ggttgcgttt
     9541 tggcgaatac accctgacaa cggggctgat tcctgaaggt tattggatgg acaacacata
     9601 tgatatttcc gccgatttct catggtttat ctattcttct ggggatgatg tacgtctgct
     9661 gacttcaaga gataatggta aaacatggca aacgtctatt atcacccaat cagttcagcc
     9721 gatacgttat cgaaaagcgg tattttatgg caacgatggt ctatttatct gtacatcagc
     9781 cagtgggatg tctgcagaaa ctttgtacat ttacactact atggatggcg gaatcacttg
     9841 gataaaaagt ggaagtacaa tgatcaatca gccagtacaa aatgtcagct tcgttacaac
     9901 ttctttaggt tttgtttcga cacgtgaaag tttgttttat acaaacaacg gaggacgctc
     9961 attcaaagaa tcagttctgt cgattccgga aaactatcag acagggggga tagatctttt
    10021 tcaatcacca aatgaagtta ctcaaataag cgcgaatacg ttagagacaa aattttattt
    10081 gttgaaaaaa ggaccaatcg atgcagggaa aatgtttgcc tgcctcttcc gttcaactga
    10141 taacggggaa acatggcaat tcgttcagca actatcgcaa gtagaacaag gagattaaag
    10201 aagagagatt gtgagcctga cgttcagcac cgagtcacaa gaaacaaatt caaaaaacag
    10261 cttctcatat ttgttgaata gtgtaactcg tgattcggag ttgacaagag caacaagaag
    10321 cgattttgaa gtatagcttc tcgtatttta caagatcgtg tcttattgcc gataggttgt
    10381 ctcttgaaca ccgtttattc gtaaaaaggg attgtgacaa gtcttttgtc actacttacc
    10441 gaacgaaact gaaggagcta tccaaaaagt atcattagta ttattctttg tgtttctagt
    10501 ggcaccacta gtacatttaa aaaagctatc gatcatggac taatcataca tgatcgatag
    10561 ctttttagat aatgtttgtt acgctatctg aaattgacta ttataaagac tggcataaag
    10621 cgttggtgat tggagtagtt cagaatgtgt tcctttttcg acgatatcgc cattcttcat
    10681 tacaaggatc atgtctgcat tttcaatcgt tgacaaacgg tgtgcaatca caaaacttgt
    10741 cctatctttt gtcacagctt ccattgcttg ctgaatcaat gcttctgttc gtgtatctac
    10801 gctagaagtt gcttcatcta aaataacgac aggaggattc gctagaatga ctcgagcaat
    10861 tgtcaataat tgttgctgtc cttgagataa cgtgccgttt tcgctagaaa tgatcgtatc
    10921 atatccgtct ggcagtgttc gaataaagtg atcacattgt gcgatttcag ccgcttcgat
    10981 aatttgttct cttgtggcat ccattttccc gtaggcgata ttatcagcta ccgttccttc
    11041 aaacagccag gtattttgta aaaccatccc aaaagaacga cgtagttctc cacgtgaaag
    11101 cttggtaata tcaagaccgt cgaattcgat ctttccttta ttcagttcat aaaaacgcat
    11161 cagcagattg actaaagtcg tttttcctgc accagttgga ccaacgatcg ctaccgtttg
    11221 ttttggcttt actgaaaaat cgacttgatt catcaatatt ttatctgatg tgtaaccaaa
    11281 ctgtacattt ttgaaagcta tttttccttt cggttgttct aaaagtcttg catctggaag
    11341 gtctggaatt tcatctgttt catctaatat ctcaaatatc ctatcgattg ctgccattgc
    11401 ggattggatc gagttgatca cataagaagc ggtagaaatt ggttcagaaa tctgattgat
    11461 gtactgaaga taagcttgta agaagccgat cgtcacacca cctgatagaa caagcatagc
    11521 accgaatacc gcacttatga tgaaggcgag ttgattaatg aaacgaatgg ccggatagat
    11581 agcacagttc ataaattgag cacgtttaaa agcgttgtat tgctttttat ttacttcgtg
    11641 tatagcagct tctgcatgag cttgctgatt gaatgttttg accactagat taccagctaa
    11701 gatttcttcc attcgattat ttaaaacacc cagttcatac tgattctgtt cagaaatctg
    11761 tttgtttttg ttcgcaatct tagttgtaac aattgaactg ccaacgatca gcaataagac
    11821 gagcaaagta agcttgcttt cgatataaaa cagcatcaga ccagcagcag ctattgttac
    11881 gacagaagta aaaaattgat tgatacctgt caataacact tgagaaagtt gattgagacc
    11941 ggtagttgtc cgactaatga tgtcacctac ttgatgattg tcaaaaaacg acatcggtaa
    12001 tgttttgaat ttttttgtga tttcttttcg caccctcaat gtgatctttt cgcttaacgc
    12061 tgccattgtc cgttcctgaa taaatgaagt gatgctgctt aagactgaac agccgatcag
    12121 caataagaca gggaacaaca atgcttgttt gatatcactg aaagaaagct gtccaatacc
    12181 tgtttttctt atttctgata agagatcatc gatcccgatt cccatgatca agggcatggc
    12241 tacgactaat aggttcccga ataaactgca tagaaacaat ccgtaaaaat atttatgttc
    12301 aggtttgatc attttccaaa aacgtatcaa agcacgcgtg ttcaacgttt ttttcttttc
    12361 catcgtatcc cttctttcta tattccttgt gattttgcaa actcctgata agtttggcaa
    12421 ttagacagta gttcttcatg agtaccttgt ccaacgattt ttccttcatc taaaacaatg
    12481 atgttatctg cttgttggat tgtactgagg cgttgagcaa caatcacgag agttttctcc
    12541 gacatgtgtt tatgaagggc tgctcttaat gctgcatctg ttttatagtc taaagcggag
    12601 aaactatcat cgaatacata gatctctgct ggtttgatca acgctcgagc aatacatatc
    12661 cgctgtttct ggccccctga ataattagaa ccgccttgag caacaaagct gtccaatccg
    12721 tcaggaaggg tgtccactag ttcttctaat tgagcgatct tgatcgcttt agacaactct
    12781 tctgttgagg catattcatt tcccatctgc aagttgctta aaattgtccc gctgaataag
    12841 aaagccttct gagggacata actgatgtgg gagcggatct gttcttgagt catttgagta
    12901 agaggaatac caccaagggt tacttttcct atcgtagggt cactaagtct caagagaagt
    12961 ttcgccaaac tactttttcc agatccggtc ccgccaacga tcgctgttgt ttttccttta
    13021 ggtattgtga aatcaatatc ttctagaact ggatcagaga tttcagtata tttaaatgtg
    13081 acatgttcaa aagcagctgc atttgtctga tcaaaggttg gttcagctac tgttttgatc
    13141 gtctcttcct caatttcgat ctctgcttgc agtatttctt ctatccgtcg taatgaggca
    13201 aacgatttag ggataatgac caataccata gctgcgatca tcaagtaagc aagtgtcagc
    13261 atagagtatt cgactacagc agtcacgaca ccgatttgta atgctccttc tgctacaaga
    13321 tttccgccaa accacaaaat agaagcataa acgattccca tgagcaaaaa agcaattgga
    13381 gtgacccaag caaatattcg gttcactttg atcatttgat tagcatagtc agcaaagctc
    13441 ttattcgttc gcttttcttc atatgattga ttatcaaagg cacggatcat attaatccca
    13501 gtaaagaatt ctctcaatgt gatggtgatc cgatccattt ttggctggat actcaaagat
    13561 aaaggtgccc ctcgtttcat cagtcgataa acaatccata cataaaaaac aacagagatc
    13621 aatgtaaccc atgttagtaa tagagaataa cgaaacatca tgagaatggt gaaaacgcaa
    13681 ataaccggtg ctggtaagat catttggcaa aataaaacaa tcatttgctg gacattatcg
    13741 acatcattcg tcattcttgt caaaagagat ccagaactaa aacgactgat atccttcatt
    13801 gacagctgtt ggaatttacg gaaatatttc tcccgcgttt ggaatccaaa cctagcggaa
    13861 gccaatgctg aaaagtaact agaggcaact gcagcgattg ttcctagaaa cgctacaagc
    13921 agcatttcaa ctccaatttt ttttataact gaggcttcgc cacttgctat acctgtgtcg
    13981 atcagctttg ctactaattt tggtacacct aatgtaccgg cgatttctaa acagatcatc
    14041 acaaaggtaa ggagagcgag tcctttgttt ttctgtaaga atgtttttaa gatagacata
    14101 ttattcctcc ttttttcctg atacttttcg attctatacc ttcaagtaac ttgaaggtca
    14161 atagaaaaaa gaataaactg aaaaagaggt gagaaaaaat gaaaaaaatg tatacgattg
    14221 gccaagtatc ggaactattt gatttgccaa aatcaacgat ccgctattgg gatgaacaag
    14281 gattaatccg ttcaagtaga caagaagaga atgattatcg attgtttgat atcgatgata
    14341 tttttatgct ttatgatatc gttttttata gaaaattaga tataccgatc aaacagatga
    14401 agaatttata tggaaaaaca ttgacggagt tatatgagac acttgatgaa acagaaagaa
    14461 gaatccataa agaactggtg gtgatgaaac aaaaacaaaa agagataagg gagcaaaaaa
    14521 aacagttgaa attgatgatc gatacaaacg aggaagaatt tcctgtagaa gagatccctt
    14581 ttgactgtat gatctcaacg gagtttgaag atattgtgga aatcaaaaaa tttctaccta
    14641 actattcaag ctttgggatg atgagtatgc cagcttccag ttcacagacg atgtatggat
    14701 tttttatcga ccctagtgaa gtacatttat ttactcaaga cgtgatttgg gagaaaaaag
    14761 atacggctgt ttatcgtcga ttcttattga aatccgagat gaaccatgcg gaacgtaata
    14821 atattttaga aatcagagaa agaatgtatg aaaaaggatg gaaaacagga gaagtgatcg
    14881 gccagtatct attgacgaat acggatgaaa acaatatcag aactgaatat tatcatgcat
    14941 ggatagaaat gaaaaaatag gaaatatgtg tttaagataa ctcgaaaatg atggttgttt
    15001 tagttataaa gaaaaatttt ctggttcgat tacgggttta atgtggggga ttattagtcg
    15061 tggatagata gaattttagt tttttagagg aaatatgtct ttaaaaatgg aatggttgca
    15121 attcttagcg atatatacga tgtaattgtc ctcttaaaaa agtatggaaa aataattgta
    15181 ttgggtgtta tgtataattc atggtgaact gagactaatg agaagaaaaa ttcatattgt
    15241 tatgagtgag attgtatcag atgagaatga taaattaaat aggtgcataa aagcattaca
    15301 cttaaaatac attgttgctt acattattac aatatgttaa taaggcaaaa ataaatagat
    15361 ggattgaata aacatatttt ttaatcaaat agtccctact gtgactttcc tcagctatcg
    15421 gtgatactac cgatagcatt tttttgctta taaaataatt ataagtattt agagattttt
    15481 cttctaacat tcttcaaaca agaaaaatc
//
LOCUS       DAFLWQ010000067        15430 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.070, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000067 DAFLWQ010000000
VERSION     DAFLWQ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.070"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            161..2221
                     /locus_tag="L1V16_002089"
     CDS             161..2221
                     /locus_tag="L1V16_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HBN1276420.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            2304..2873
                     /locus_tag="L1V16_002090"
     CDS             2304..2873
                     /locus_tag="L1V16_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1276421.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(3048..3854)
                     /locus_tag="L1V16_002091"
     CDS             complement(3048..3854)
                     /locus_tag="L1V16_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276422.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            3992..5506
                     /locus_tag="L1V16_002092"
     CDS             3992..5506
                     /locus_tag="L1V16_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HBN1276423.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(5909..6892)
                     /locus_tag="L1V16_002093"
     CDS             complement(5909..6892)
                     /locus_tag="L1V16_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HBN1276424.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(6897..7544)
                     /locus_tag="L1V16_002094"
     CDS             complement(6897..7544)
                     /locus_tag="L1V16_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1276425.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(7629..8261)
                     /locus_tag="L1V16_002095"
     CDS             complement(7629..8261)
                     /locus_tag="L1V16_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBN1276426.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(8277..8828)
                     /gene="coaC"
                     /locus_tag="L1V16_002096"
     CDS             complement(8277..8828)
                     /gene="coaC"
                     /locus_tag="L1V16_002096"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HBN1276427.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(8825..9562)
                     /locus_tag="L1V16_002097"
     CDS             complement(8825..9562)
                     /locus_tag="L1V16_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HBN1276428.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(9559..10548)
                     /locus_tag="L1V16_002098"
     CDS             complement(9559..10548)
                     /locus_tag="L1V16_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBN1276429.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIITFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            10806..11348
                     /locus_tag="L1V16_002099"
     CDS             10806..11348
                     /locus_tag="L1V16_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1276430.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            11365..12450
                     /locus_tag="L1V16_002100"
     CDS             11365..12450
                     /locus_tag="L1V16_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1276431.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            12462..13268
                     /locus_tag="L1V16_002101"
     CDS             12462..13268
                     /locus_tag="L1V16_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1276432.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            13269..14096
                     /locus_tag="L1V16_002102"
     CDS             13269..14096
                     /locus_tag="L1V16_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1276433.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            14093..15166
                     /locus_tag="L1V16_002103"
     CDS             14093..15166
                     /locus_tag="L1V16_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1276434.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
BASE COUNT         4964 a         2784 c         3140 g         4542 t
ORIGIN      
        1 aagtacataa gttattattc cgattttctt gaaacaataa aaaatcaaaa aaaatactct
       61 cctaatagtc catcttcttt tgattttatt tatataatga aatcatctta tgaaaattac
      121 tacttcatgt ttagacaaga gtagggagga ctaagaataa atgtgttcaa aaagacgttc
      181 aaaacaacta aataaacacg cttgtcgttt agataaggaa cggtcgtgtt ctgaaaaaca
      241 ctacgttaag tttatgatgc gcacgatgct gatcagttta tctgtaggtg tctatatgca
      301 tgtacccgtt caggcaacga cacaaaccat caaggtcgta cgtacctctg tttctgagac
      361 cactgattcc cctatcacta ttactcatac tttcactgat gcaaatggaa aacagctact
      421 tcctgcattg acttcctata ataaagtcag ttatcctcca acgataaacc actactggtt
      481 aattcctaac aaaacattat ggacatcgga aaccggaagc agtgtgccgc tttctatctt
      541 ttccgatatg actgatccta caaaaggtga tcagttaaaa cagatcactg atattttgaa
      601 tcatgctttg acagatataa aggacggtgg aagcgcacaa gtttcttatg tatatgaaaa
      661 agattattca cagtttgaaa gaaagaaaat cgatgttctg gcagggacaa aagtttcgat
      721 atctgatctg gtagaaaggc tgaagaacgc agatggaaca caaggagata tgtccaaagt
      781 aatttcaaac aatgggaata tcgtggatac gactaataca ggaacatcta ctatttcctt
      841 gtcctatttt gatccaattg ctttaaaaac aatgactgca tctgctgtga tccatgttcg
      901 tgctgatcaa acagctatca aaggaaaaga tcttcactta agaacaggag agagttacgc
      961 ccctaaagat cttgttgaat atgtaacaaa aagcgatgga acttcaggaa ataaagaaga
     1021 aatcaaaatg aacgggacag tagatactac aactccggga gaatatcccg ttgtattaac
     1081 ttatatagac tcgaaaacat caaatgtggc agaaacaaca gctgtagttt atgtagaagc
     1141 atctgctgct tcatcgactg tcatcactca ttttatagat agtcaaacaa ataaagaact
     1201 tcaagcagaa acacatatga gtagtgtaaa tcgtattcct gatttgcgcc tacctgctga
     1261 attttctgat cgagtgccaa atatagattt atcgacttat gaacaaaatg ggaaagtcac
     1321 ttctatttct gattggatgc aagcaaacgg attagacaga aaaagtcact ggtcggagat
     1381 ccttgaagta cttcactcag aactgatgaa taataggaag caatcaggag gggaaattac
     1441 ctttacttat gtttatatac cagacaatcg ttcattagaa ggtcatgatc ttattgttca
     1501 tccaaacgaa aaaataaaca aagaagagtt gatccaatca gcaacaaatt ccttaggtaa
     1561 acccgtaccg ttaaaggatg tatcggttac aatcaatgaa gtaccattgg aggatggtta
     1621 tttgaccaaa caaacaggtg attttacgat tatgtatagt tatcatgacc cgtattcact
     1681 ccaagaactc catgctcagt cactattaca tgttttacca ttaaacaaac agatagatca
     1741 aaaagaacaa aaaagacaag aagaaagctt gtcagaaaaa aaacaacaaa tggctcatgc
     1801 agtttctcca acagggaaag taaaacaaac aagaagccta gagttagcaa gaatatctag
     1861 aaaaatctca gaatctaata aaacgataag gcaagaagct catttggccc cacaagtttc
     1921 tggattggaa aatgaaattt tagagcctaa aataaaacaa caatcagaaa aagaatttgt
     1981 tgctaaacag tcggaagatc agaaggaatc agatgaccag aaggaaacga agaaaaaacg
     2041 cttgtcaact attgattcca ccgatgagca tctgcagccg caagtaccac ttcctagtcc
     2101 gggaacaccc gcacctggtg gaggtattcc ttcttctgct ttaggagatt tcatgcgagg
     2161 tatggcagga acatgggtat acgctaatcg aaatgaattt gacgcagatg actggttctg
     2221 atttatatct ctatctgtta tagtcaaata agtagctgag tcatatgtta tttggcataa
     2281 tggagacgag gagggataga aaaatgttag ataaaacgtt accttacgca gaaatctgga
     2341 tgacaagacc acttcaacaa aatgttccaa tcacgccttt agcggaaggt tttgaatttc
     2401 gattttatca aaaagaagat gaatctgctt gggcggagat tgagacttcc gttggggaat
     2461 ttcaaacgac agatgaagca cttgagtatt ttcaacaaaa ctttgctcct tatcctgaag
     2521 aacttgaaag aaggatgttt tttgtagaga caaaaaaagg agaaaaagta gcaacctgta
     2581 ccgcttggcg aaaaaaatca agagagcaag tgtatccggt ttttcattgg ttagcagtga
     2641 aaccagatta ccaaggaaaa gggctcgcaa aagcattgac tgccagagtc ttgcaagaat
     2701 ttcctaccct ccatacggac ggaccaatct atcttcacac acagacatgg agccatcagg
     2761 cgattgctct ttataaaaaa atgggtttta cttttattgc tgaaaatcta gacggcacac
     2821 ctaatccaga ttatgaaaaa gttatgcagg ttttaagtaa attagataaa taacgaaatg
     2881 gtgaaataag tcctcagtat tgggataaaa aacgaaatag tcattcctca tatcttactt
     2941 ttttgagtta atactatcgg ataactaatg gcatgccata cattcaaaaa agaaggggca
     3001 gtgacaaaag tattgtcact gccccttctc ttgtttttta gcatgtttta tcgtttgatt
     3061 tttttaggaa taaaattctt gatgaacgta aatttttggt aatcgtttcg actatagagg
     3121 taaccaaata cactgaaaac aactgctcca ataaaattaa caaataaatc cttcatagta
     3181 tccatgattc ccacgtctaa gtaaccattt tggatgattg ttttatctgt tttaccatct
     3241 gcattttgac tttcaatgat tgtccgagtg atatctggaa catgatagac agtgtttccg
     3301 tctttactta actccacact attgatttgc tggatgatcg tatctttttg catatcgaat
     3361 tgcagtaatt tatctgctga aaattccaca aactcccaca taacaccaac tgtcatcgaa
     3421 aaacagaagg aaacaactgc tagtaataaa ggagtcaagt tcatggtttt tgtattttta
     3481 ttgagcaaat aaacaaggga aaagccgaca cccccagcta aaaatccgct gaatgcatgt
     3541 agaaaagtat cccacattga aaaatagcca taaaaatcac ttaactctcc taaaactgtt
     3601 gaactaaaaa taaaagataa caaaatgatt tctagcatat ttggaatctg tatctttaat
     3661 atcttttcca gaaaataagg gatttcaaat aaaattaatg tcagtaataa aagcattgta
     3721 tttccccagt gttggttcca gacctgatcc actagcataa taacgacgat gatacgtaat
     3781 aaaatataga ttccgtttgt gattctacct gcagtttttg tactgttcgt aaaaaaggtt
     3841 ttcaaatgat tcataaaata actccttcat gtatatcctt aattatacta agaagcgtgt
     3901 gtttaccaaa gctatatgac ttaaagaaaa acagagttga tattgtgaaa aaaatcactt
     3961 aatatagtat aaggagaaaa gggggataca aatgaaaaaa ttagttgctg gtttattaac
     4021 agccgttgca cttcttgcta tgagcgcatg cggcgcagat cagaaaaata cagcgcagac
     4081 aagttctagt acgaaggaat ctgccgaagt atcatcaggc gcttctgaac aagtatatac
     4141 agatccaaaa gaaatgaaag aatcttatga tgtcgtgatt attggagctg gtggtgcagg
     4201 gatggcagca gctatcgaag caaaagatgc tgggttgaat ccagtaattt tggaaaagat
     4261 gcctgttgcc ggaggaaaca catctaaatc atcaagcggt atgaatgctt cagaaacaaa
     4321 atttcaaaaa gaagaaggaa tcaaagactc gaatgatgcc ttctatgaag aaacgctaaa
     4381 aggtggtgga ggaacgaatg ataaagaaat gcttcgatac tttgtcgatc actctgctga
     4441 tgcggtcgat tggctagatc aaaacggtat caaactggac aacttaacga tcactggagg
     4501 gatgagtgaa aagaggacac atcgtccgtc tgatggctcg gctattggtg gatacttagt
     4561 ggaggggtta ttgaataacg tccatgagcg ggaaatccct atttttgtca acgcagatgt
     4621 gacagacatt aagaaaaatg gggaaacggt caatgaagtg actgtacatg ttcaaggaga
     4681 agaaccaaaa gaggtcaccg gaaaagcaat cgtagttacc acaggcggtt ttggtgccag
     4741 caaagaattt attgaaaaat atcgtcccga tttagctgat tatattacga caaatcaaga
     4801 aggatcaact ggagatggta tcaccatgat tgaaaaatta ggtggacaaa ccgttgatat
     4861 ggataaaata caaattcatc caactgtgca gcaggatgag ggggtcttga ttggtgaggt
     4921 tgttcgcgga gaaggagcaa tcttggtcga tcaagagggg aaaagatttg tcaatgaaat
     4981 ggatacaagg gataaagtat ctgcagcaat tacagcattg cctgaaaaat cagcttattt
     5041 gatttttgac caaggcgtgc gtgatcgtgc cacagctatt gaattttatg accaaaaagg
     5101 atatgtcaca actggaaaga caatggaaga attagcagaa aaaatcgatt taccaaaaga
     5161 aacactagca aaaacagttg atggatggaa tacggatgtt gcggagaaaa aagatgctca
     5221 attcaaccgt gccacagcca tggaacatga cttatcgtct ccgaattatt atgcgatcaa
     5281 aatcgcacca ggaatccatt acacgatggg cggtgtgaaa atcaatacga acactgaagt
     5341 attagataaa gaaaaccagc caattagggg gttatatgct gctggtgaag tcacaggtgg
     5401 cttacatgga aacaaccgga tcggtggaaa ttcagttgcg gagatcatta tttttgggcg
     5461 acaagcgggc atacaagcag ctcgatttgc ttcggaaaat gaatgaaata gaacgtaaat
     5521 aaaaagaggt tgtgaaatca gcgttttgag ctaataccga gggtcagctg attgaacact
     5581 gtttagtgaa gaggttgtga aaaagctgcc ctgcatcaag taataagaac agccaagtaa
     5641 aaacagcttc ttatgttttt aacttggttg gacttattac cgcagatgca agcttttgaa
     5701 caccgtttat tcggaaaaag agcgtgggac aaaagtaaag aacacttttg tctcacgctc
     5761 taaacacgta taaacggcgg aagcagaaga aattccttcg gaaataagct gaaattcaca
     5821 aaaatttgaa aagcaatttt cgtgaatttc ttcttatttc ttggagttaa acgcttctgt
     5881 cccagcctct tttttgatca gcatgatttt attcagttat cttcaaaatg atttttccga
     5941 tgtttttgtt tgcttccata tattcatgcg cttgtttgac tgcgctgaat tggaatgtac
     6001 ggtcaatgat tggccgaatc ttgccatttt ctagaaaagg cccagctttt tgcataaaag
     6061 tttgtgcgag ctctgcttta tactgatcac ttctaggtgt caataatgta ccaagcagtt
     6121 ggacacgttt cccaatcaat acaccaaggt ctatctcagg cacgatggtc ccacctagca
     6181 taccaatcaa gacccaacgt ccatcaacgg ctatagaagc taaattcttt tcccagtaag
     6241 aagcgccgat gaaatccaaa ataacatcga ctccccgacc ttcagtgatt tttcgtacct
     6301 cttcttgaaa gtcttgtttt ttatagttga tcaattcatc tgcaccaagt tctttacaaa
     6361 aggcgagttt ttcttctgat cctgcagtaa cgatgatttt cgcgtgagaa agctgtctag
     6421 ctaattggat cgctgctgtt cccacaccac ttgctcctgc atggatcaag acagtttcgc
     6481 cttcttgtaa ttttccaagc cagtaaagtg tttgataagc agtcaaaaaa acttctgaga
     6541 ttccagcagc agaaacatag tctagcgtat cagggagaag gattgcacga tcggcaggca
     6601 tcacagcata ttcggcataa ccacctagat tgactaatcc gtatactttt gtcccaggag
     6661 taaaagtgga gatatcactt ttattctcaa ctacctctcc agctacttcg actcccaaaa
     6721 tagggtaggg aggtttcaaa gagactgatt ctcttttcat aatatctgtt cgattgacag
     6781 ctgctgtatg gactttgatc agtaattcgc cttgttttgg tttaggaaca ggcacttcaa
     6841 tttgttctaa tacatctaca gaaccaggat gcttgattga aatggcacgc atggatctat
     6901 tcctcctttg cccattcttg gaatgctgta ttcaactctt tgctaccttc agaaagtact
     6961 agagtcgtac gagaaatatc cgtttcttcc actagagcgg caagtacagc agcaactgta
     7021 gagcgagtga tcgtttttga tgccttctca ttaggcttag ttaattgaat ggaagtaact
     7081 tcttcatcgt tagtcaatgt gactggttga agaatgacaa aatctaagtt agttcgtttc
     7141 agccattcat ctgcataatg tttagtaata taataatctg tcatggactc aggccatttt
     7201 gctggttcat ctgcataaac agcactgacc atcagatagc gagagacatg cgcattttca
     7261 gctgcgatca ctgttttgat tgcgccatcc aagtctactt gcagaagatt ctttccttga
     7321 gagccggcag caaaaatcaa tacatcgatg cctttgaatg cttcggtcat tttttccacg
     7381 gaccaagtta aatcaaaaga gacatacgaa acattctctt tttttactaa tgtttgggaa
     7441 gcaacatctc tcacccctgc aaaaatttca tgggaacttg gagctaaatc ttttatcagg
     7501 tgtcggccaa tttgtccgtt tgcacctaca acaaaaattt tcatttggat catcctttcg
     7561 acgtcaaatc tttccattca atagtaacac caaaagagaa aaaaatcaga gatcggctac
     7621 gatgactatc agttagtaag agaagggtgc ttgaagtatc ttaacaagac attgcatact
     7681 gctgcagtcg caagacctgc gacgattcct tcaggtatac cacttgtaaa aataaccgct
     7741 agaatagctg aataaacagc atttaaattt gttccgatga ctttggcata atcttgctgg
     7801 aataaaaagt agatcatatt catcactaaa atcgtattgg tcaatgaacc ggaaagtcca
     7861 gctaagaata aagaaacgga atctgctttt tgtttcatta gtttgcgcag acctttataa
     7921 acgaaataag gaaccacccc aatcaagatg cgaggaataa acgcgatcag caaggctttc
     7981 cagcttccat gttctgttcc gatgactggg ataaacggag aaaagacaaa agacaaaggt
     8041 gtttggataa ctgtgctacg gatcatgctg atcagtccaa atgtaccgcc aagaaaagca
     8101 cctagtcttg gtcctaaaac gatcgaagca atgattacag gaatatgcat ggttgttgca
     8161 ttgattggac cgatagggat aaaacctaaa ggcgtaacag ctaataaaat caaaatagct
     8221 aaaaacatcg cagttaatgt aaagtttttt gtatttttca taagtactcc ttttttctaa
     8281 gcatttcttt cattaagagt cagcatgacc tgttcgatga tcgtctgaat atcagctaag
     8341 gcaccttttc caaaatctcc acaagctaaa agagattctc ttggttcaat ttcctgatag
     8401 ccgacagatc tcaatgtttc cagattacgc tgagtgatcg ggttttgata catattcgtg
     8461 ttcatggcag gggcaatcaa ttttggtgtt cccactggaa gcgccattgc gactgttgaa
     8521 agaagatcgt ctgcaatgcc gtttgctagc ttgccgataa tgtttgctgt agcaggcgcg
     8581 atgagaaaca agtcagcttg ttttgctagt tcgatatgat tgattacctg cggatttgat
     8641 tcttgcatga cgtctgtatg gactgcgcgc ttcgacagag attgcaaggt taatggcgtg
     8701 ataaaatgtg tgctgctttt agacataatc acatctacct gggcacctaa tttgacgaat
     8761 tgacttgtaa gatcagcgct tttgtaagca gaaatacttc cagtaacgcc tagtaagatc
     8821 tttttcattt tgattcctcc agtctaattt tctcagtaat caatgcagca atctcagatt
     8881 tactttgagc ttcttccact gttccatctt tagataagag atagccgtgg tgtgtctcgc
     8941 catggatttc cgtcaaatca tttgcgaaaa taaaatcagt tttgttattt atcagactat
     9001 tttttgcgac tgccagaaga gattcctttg gtacatctac taatagtttg aaaccaatga
     9061 tttttgcttt tggctgccat tcacgtagat aagaaatgat ttttggtgtt ttcttcaaaa
     9121 cgagcacaag atgctcggtg ttagaagaga tctttgaaac agtggtatct gtctgttcat
     9181 tttccgcaaa ccaattgtcc agttcttctt gcgttgaaga agtgggtagg ttttttgcca
     9241 gctgttcttc tgaaaaacta aaagcaggag taaaatcact gactgccata ctgtggataa
     9301 tcgcatcgta gtgttctttt ttcgttagtt cttctaattg taaaaataag tccagtgcag
     9361 attcgatcgt ataaatcgtt atattggagt gtcttttcgg tttcagtgct tgtttcgtag
     9421 tcacgtaatc gattgtggta tccggattgg cagctaaata atcagctaat gcttgcccta
     9481 atcgtcctgt cgaatgattt gtaatagcac gtacttgatc gattttttca gtcgttcctc
     9541 cagctgtgat tagaatcttc atttatggtc acctacattt actagtgttc ttccttggtg
     9601 tgttccagca agtagtttag atgctgtttc aggcaattga tccagagtaa tctcttggac
     9661 gaccagttca tctgcaatct gcaaatccgc catctgttgc cataaagaaa gacgttgatc
     9721 tattggtaca ttgacagaat caattccaat caactggatg tttcgcagaa taaaaggcaa
     9781 gacagtcgcg tttagtttga ttcccccagc attgccacat aaagctactg caccgttata
     9841 agagatcaat ggaagaagac tgcttagctg ctcgccacct actgtgtcga tgacatagtc
     9901 gatttgctgt tttcctaaag cttttgttgt ctctggcaga aattcatcag gtcgtacgac
     9961 ttgcaaagca cctagacttt ttagccatgt gacagactct tcttttctgg aaaaggtaat
    10021 gattgactgg aatcctagtt tatgtaacag ggctatcgct gtactgccta caccgccaga
    10081 agcaccagta acgacaactt ttttatcgga ggtcatacct tgacggatta aagcgttcac
    10141 acacaacata gcagtaaacc ctgctgtacc aaggatcatc gcttgacgca gcgtcatatt
    10201 ttttggtaga ggaactaacc agtctcctgg tactttttga tattggctat aaccgcctgg
    10261 atgggtgacg ccaagcccaa aaccagtagc aagtacaaga tcttcttttg aaaaacgtgg
    10321 attgttactt tggacgacag ttccggataa atcaatccct ggagtcatcg gatatgttcg
    10381 tatcacctga ccagactcgc tcattgccaa tgcatcttta taattgacat cagaataggc
    10441 aatttttacc aagacttcat tttcagccaa ctcagtaaat ggcagatcac tgattgctgt
    10501 atggaaaaca ggttccttta ttacctgaaa agatcgaaaa gcgttcattc gtgagacact
    10561 ccttttaaaa ttttctttta tcataccata aagcctactc ttttattctt gttcttccgt
    10621 aaatttagac aaaaattagg tgaaaaataa agaatcaaac aactagaatt tattccaaaa
    10681 gataaagaaa tattcagcaa aaaaaatttt acaaagggtt gcctttttca ataaatttcg
    10741 tatactaata cgagtggtag taaacaggaa gtttactatt agaaaacttc gattcggagg
    10801 aaattatgga aattggtgag aagttaagaa atttgcgcat ccaaaagaat ttgacacaag
    10861 aagaactagg cgaacgcaca gatttgtcaa aagggtatat ttcccagttg gaacgagatt
    10921 taagttcacc atcaatggaa acattctttt ctattcttga agtcttaggt gtgactccag
    10981 aagaattttt tcatcaagaa gcagcgaatc tgcaagtggt ttattcaaaa gaagatcata
    11041 cggtttattt cgatgaagaa aacgggtatg aattggaatg gctcgtggct gattcgaatg
    11101 aaaaagaaat ggagcctgtc ttgctgactt ttgaaggtgc aggagaatat aagacgtttg
    11161 aaccttcatt atctgaaacg tttatttttg tattagaagg ggaattagag ttaagcttag
    11221 gagagacggt ctatgtggca aaagcaggac agtcgatcta ttatcaagcg acaaaacaac
    11281 atcaattaag gaatcatctc aaaaaacgaa caaaagtatt gattgttgca acgcaatcat
    11341 atttgtaata tagggggtaa aaacgtgggg aaaccaatca tttcatttga tcaagtagtg
    11401 aaacgctatg atgatgaaac agtattaaaa aaagtaagtt ttgagatcga acaaggaaaa
    11461 ttttatacac tgcttggtcc ttccggctgt ggtaaaacaa cgatcctacg tattatagct
    11521 ggattcaccg aagctacaga aggggacatc tattttgaag ggaaacggtt gaatgatttg
    11581 ccagctaata agcgacaagt aaatacagtc ttccaagatt atgcactttt tcctcatatg
    11641 aatgtttttg ataacgttgc ttttggattg aagatcaaga aaatgtccaa atcagatatc
    11701 gaaaagaagg taaaagatgc tttgcgtatg gtccagcttc ctggatacga aaaacgggag
    11761 attagtgaaa tgtctggtgg tcaaagacag cgtgtagcga ttgcacgagc aattgtaaat
    11821 gaaccgaaag tattgctatt agatgaaccg ttatcggcgc ttgatttgaa actacgtaca
    11881 gatatgcagt atgaactgcg ggatctgcaa caacgattag gaatcacgtt tatttttgtt
    11941 actcatgacc aagaagaagc gttggcaatg agtgatgaga tttttgtcat gaataaaggg
    12001 aaaatcgtcc aaagtggtac acccgtagat atttatgatg agccaatcaa tcatttcgtt
    12061 gctgattttg ttggggagag caatatcgtg gacggtgtaa tgatcgaaga taatctagtt
    12121 gagtttgttg gtaagcaatt tgaatgtgtc gatggcggga tgcgtctaaa tgaaccagtt
    12181 gaagttgttt tacgcccaga ggatttgacg atcacgacac cagataaagg aaaactagtc
    12241 gtaacggtcg atactcagct gtttcgtggt gtccattatg aaatcatctg ttatgatgaa
    12301 cagcaaaatg aatggatggt ccattcaacg aaaaaagcta aagaaggaag caaagtagga
    12361 ttggcctttg agccagaaga tatccatgtc atgcgtttca acgagtctga agaagaattc
    12421 gatgcacgtc ttgacagcta cgaagaatag gggggacaag aatgaaaaca atgcgcagga
    12481 tctattccgt cccttatatt ttgtggctcg gtttattcgt gatcgcgcct gtattaatga
    12541 tcatttatca atcttttttt gatatgaatg ggcaattcac gctgaataat tatctatctt
    12601 attttacgtc ggggacatcg ctttctatga cgatcaattc tgtatggtat gcatttttga
    12661 tcacgttttt cacgctgatc atcagttacc cgactgctta ttttttaaca aaactgaagc
    12721 acaagcaatt atggctgatg ctgattattt tgcctacatg ggtgaatctg ctgcttaaag
    12781 cttacgcatt tattgggatt ttcagtgtgc acggcagcgt gaatcatttc tttgatttta
    12841 tcgggatcgg gccgaaacag atattattca cagacttcag ttttctgttc gtggcaacgt
    12901 atatcgagat tccatttatg attatgccaa ttttcaatgc attggaagag atgaatcctt
    12961 ctttgatcag tgctagtaga gatttaggcg cgaatagctt tgagaccttc cgacgagtga
    13021 tttttccgtt atcattaaat ggtgtgaaaa gtggtgtcca agcagtattt attccttctc
    13081 tttctttatt catgctgact cgtctgattg gcggaaatcg ggtgatcact ttaggaacgg
    13141 ctatcgaaca gcatttcttg gttacacaaa actgggggat gggttctaca atcggtgtga
    13201 ttttaatcat tgctatgttc atcgtgatgc tcctgacagg cgagaagaaa aaaggaggtc
    13261 gctcataaat gaaaaaattt aaatggtcgt atctttattt agggatcgtc tttttattct
    13321 tatatgcacc gatcttctat ctgatttttt attccttcaa tgaaggagga acgatgaaca
    13381 gctttacagg atttacttgg gaaaattatg aagctgtttt tgaagataca cgtttgatca
    13441 ttatcgtatt gaatacgttc atgctggctt tcttatctgc attgatcgcc acgatcatcg
    13501 ggacatttgg ggctatggga atctattaca cgaaaaaacg acgtgcacgg acagcgttgt
    13561 tgagcatgaa taacatctta ttagtctctc ctgatgttat tatcggtgct agtttcttga
    13621 ttttctttac actactagga ttcggattag gttttcagag tgtattgctt tcccatattg
    13681 ctttcagcat tccaatcgtc gtcttgatgg tcttgccaaa attgcaggaa atgaacgatt
    13741 caatggtcga tgcggctaga gaccttggtg ctaataattt ccaagtagtc aaaaatatca
    13801 ttttgcctta tctttctcca ggaatcatag ctggatattt tatggcattt acctattctc
    13861 ttgatgattt tgcggttaca tttttcgtca caggaaatgg ctttacgacg ctctcagtag
    13921 agatctattc tcgtgcaaga caaggaatca gtttagaaat caatgcgcta agtgcgttag
    13981 ttttcttgtt ctccatgata ttggtcattg gatactactt tattagtaaa gaaaaccgtc
    14041 caaaacggct gaagaaaaac agaagagtac gcgagggggt ggcacggctg cgatgaaaaa
    14101 attacaatct ctgtttttag gtattctcat cattattgcg gtgctgctgc ttggtgttcg
    14161 tcaacttgaa aaaacaagtg gcatgagtgg agcaaaggta cttaccatct ataactgggg
    14221 agattatatc gatcctagtt tgatcacgaa atttgaaaaa gaatatggat acaaagtgaa
    14281 ttatgaaaca tttgattcta atgaagcgat gttcacaaaa atccagcaag gtgggacaaa
    14341 ctacgacatc gctataccaa gtgaatatat gatccaaaaa atgatcaaag aaaaactagt
    14401 acttccatta gatcattcga agatcaaagg attaaataat attgatccac gatttttaga
    14461 cttggatttt gatccagata atcagtattc gattccatat ttttggggaa ctttagggat
    14521 cgtatataac gataaattct ttgatgcaaa tcaaattaag cattgggatg atttgtggaa
    14581 gccggaatta aaagacagtt tgatgctgat tgacggtgca cgagaagtta tggggctttc
    14641 tttgaatagt ttaggctatt ctttgaatag taagaatatg gcacagctga cagaagcagc
    14701 aaataaattg aatcatttaa caccaaatgt caaagcaatc gtggcagatg agatcaaaat
    14761 gtatatgatc aatgaagaag cctccgtggc agtgacattt tctggcgaag ctgccgatat
    14821 gatgtgggaa aatgaacatt tacattatgt gatcccacca gaaggatcca atctttggtt
    14881 tgataatatc gttatgccaa aaaccgtgaa aaataaagaa ggtgcctatg atttcatcaa
    14941 ctttatgcta gaaccggaaa atgcggcaca aaatgcagag tatattggtt attctacacc
    15001 aaatgaagaa gcaaaagcgt tattgccaaa agacatttcg tcggacgaac aattctatcc
    15061 atctgatgac acgatctccc atcttgaagt ctacaaagat ctaggatcga aatacctagg
    15121 catctataat gacctattct tagaattcaa gatgtatagg agataatggc aaaactcagt
    15181 aagaatgggg acttatcaac gttctaaaga gctaaaaatc gtcctttttc tatctgagtt
    15241 ttccaatctt ctaccaaaag cggatgaaac gccgcttttt ttgtgttatt ttattttttc
    15301 taccacgttt ttctaccaga gaaaagtgga caaaaccatt gtaaaatagg gcccgagacg
    15361 ggctagtaaa tctaagattg aaaaagttac agaaggataa agtaattgga aactatgcaa
    15421 atatacttaa
//
LOCUS       DAFLWQ010000068        15228 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.071, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000068 DAFLWQ010000000
VERSION     DAFLWQ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15228
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.071"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..151)
                     /locus_tag="L1V16_002104"
     CDS             complement(<1..151)
                     /locus_tag="L1V16_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276435.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNY"
     gene            234..842
                     /locus_tag="L1V16_002105"
                     /pseudo
     CDS             234..842
                     /locus_tag="L1V16_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            862..1890
                     /locus_tag="L1V16_002106"
     CDS             862..1890
                     /locus_tag="L1V16_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBN1276436.1"
                     /translation="MNRIWNKSHRNNCSLLLILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILIRNSEKESSPNLKLKKTYADQSDGRNVIKANLQNPNAS
                     YMFGLTTSVEIYKKETKEPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKG
                     AWKEKRWNLHTDFEITDDAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFI
                     LKERRKKK"
     gene            1887..2645
                     /locus_tag="L1V16_002107"
     CDS             1887..2645
                     /locus_tag="L1V16_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBN1276437.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPNEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QNGTDSTGTATQVQNFVQVTDKSGIYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGTPSTISGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEGKA"
     gene            complement(2731..3471)
                     /locus_tag="L1V16_002108"
     CDS             complement(2731..3471)
                     /locus_tag="L1V16_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1276438.1"
                     /translation="MKKYFIIEDNQFHSEWIIKELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            3532..4785
                     /locus_tag="L1V16_002109"
     CDS             3532..4785
                     /locus_tag="L1V16_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBN1276439.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGFIALMVVTLL
                     FPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGLRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            5086..5334
                     /locus_tag="L1V16_002110"
                     /pseudo
     CDS             5086..5334
                     /locus_tag="L1V16_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877177.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            5456..5782
                     /locus_tag="L1V16_002111"
     CDS             5456..5782
                     /locus_tag="L1V16_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBN1276440.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLQLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEF"
     gene            5850..6563
                     /locus_tag="L1V16_002112"
     CDS             5850..6563
                     /locus_tag="L1V16_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBN1276441.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYLVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PIFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEEKEIVTLITCGDMDAVTRLVVQGELESVTP
                     IKDATDDMRSAFNLETKTF"
     gene            6873..7725
                     /locus_tag="L1V16_002113"
                     /pseudo
     CDS             6873..7725
                     /locus_tag="L1V16_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            7846..9711
                     /locus_tag="L1V16_002114"
     CDS             7846..9711
                     /locus_tag="L1V16_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1276442.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            9759..11168
                     /locus_tag="L1V16_002115"
     CDS             9759..11168
                     /locus_tag="L1V16_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBN1276443.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            11276..11977
                     /locus_tag="L1V16_002116"
     CDS             11276..11977
                     /locus_tag="L1V16_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1276444.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            12136..12615
                     /locus_tag="L1V16_002117"
                     /pseudo
     CDS             12136..12615
                     /locus_tag="L1V16_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            13463..14038
                     /locus_tag="L1V16_002118"
     CDS             13463..14038
                     /locus_tag="L1V16_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HBN1276445.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            14038..14478
                     /locus_tag="L1V16_002119"
     CDS             14038..14478
                     /locus_tag="L1V16_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBN1276446.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            14494..15195
                     /locus_tag="L1V16_002120"
     CDS             14494..15195
                     /locus_tag="L1V16_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBN1276447.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         5125 a         2535 c         3203 g         4365 t
ORIGIN      
        1 tataattgtt aataccgtta tagatcaaaa cttcagaacc attctctctt ttgatgcgca
       61 tcgctaactt ggcagccgcg ggtttacctt tttctggtgc actcttttcg tttcctaatt
      121 ggacaggaac aatctcattt aatttataca tagaaaacct ccagacttct tgatagctca
      181 agtatatctt gaggtgcatt tgttagtaag gtactgttct atggggcgct tacccagaaa
      241 atcaactttt tgcaggagat gtattagaaa ttgtattaaa cgaccaagca ggagaagctg
      301 ctgctaaggg tgtgcagaac aagccaagta ccaacgatga aattgggaat cacaatccaa
      361 gtgatacgcc agttgtttat catgatgccc cgccttttgc acctgctacg aagattgtag
      421 tagaaggtgg tctctcattt cttgcccctt ccaaactcga ttgtggtcag atcaaagcaa
      481 ctgggttgac gcaagaagca tttggccaaa tggatataca ggaaaaatta tggatttatg
      541 atcagcgaga aacaaaaagt ccatggatct taacgataaa attatctcag cctttcacaa
      601 ccgatgcagg attttctatg caggatgtcc tatatttcaa gaaagctgag gagtatcaat
      661 tagtgaatga agaagaactg gaaattgtca gaggacaaaa ttcaacgaat gtgcaaacag
      721 attattcaga atatttaaat aatggtcggg cgtttaaact tgtcttaacc aaagaaaatc
      781 agatagctgg taattactca gcagagatga catggacatt agcagatgcg ccgacagaat
      841 aaagatcaag gagaatgatt gatgaatcga atatggaata aaagtcatcg aaacaactgc
      901 tctttacttc tgatccttct ccttggattc atcctttggc agacacctgt ccatgcctcc
      961 gaattcaatt ttgcggtaga ttttgaatta ccggctaatc agattgataa gaacaaaaca
     1021 tatataaatg taaggatgga gcctgggaaa acacaggaaa tcccctacac ggtctttaac
     1081 cgaacagata aatcagtaac agttgagaca ttgatccact ccgctacgac gaattcaaac
     1141 ggtgtgatcg aatatggaga atcaaaaagt aaatttgatg aaacattaag ttatgatatg
     1201 aaaaacttag caaaaacagt gggagaaata actgtccctc ctcaaagtgc ggtcactgag
     1261 acactttcac tgaaagctcc agaaaaagag ctggctggtg tggtcgcagg aggaatcacg
     1321 tttcaagaaa aaaaagagaa cgtttctaac aaaagtacag ttggtgtcgt caatcagttt
     1381 tctcaagtga aagcaatctt gattcgaaat agcgaaaaag agtcttcccc aaatttgaaa
     1441 ttaaaaaaaa cttatgcgga tcaaagcgat ggaagaaatg tgattaaggc gaatcttcaa
     1501 aatccaaatg cttcttatat gttcggcttg actacatcgg ttgaaatcta caaaaaagaa
     1561 acaaaagagc cttatctttc aataaaaaaa gaaaaaatag atgtagcacc caatacaaat
     1621 tttgatttac ttgtcccatt agaaggaaaa aaattagctc cgggacatta tcaagcggtt
     1681 gtgaagggtg cttggaaaga aaaacgctgg aatctccata ccgattttga aataactgat
     1741 gatgcagcgg accaattgaa tgaaaaggat attgatttaa aaaatcagcc agaaacattt
     1801 gactggcgat ggctgatact tgttggagtc attcttattg gcttatttgc tggattattt
     1861 attttaaaag aaagaaggaa aaagaaatga aaaaaacaat tgcattaagt accgttctag
     1921 ctggaagtct attattatgt acacaaagtg tttttgctga gaataagagc tcagccacta
     1981 cagaaggaac gatttctgta acaaaaccag atgccgcaaa tcctgaagac gttgttccag
     2041 ttcctcctgt tgatccaaat gatcccgata cgccgtttac acctaacgaa ccaaatcagg
     2101 gaacatccgg attactgacg attgaccaag ctccagatct tgattttgga acaatcaagt
     2161 taggtacagc aaaaacagta tatgctgcat tacaaaacgg aacggacagt acagggacag
     2221 caacacaagt acagaatttc gtacaagtaa cggataaaag cggaatttat gccggttgga
     2281 aactatcagt caaacgaaca gaatttattg gtacaacatc tgatacgaat aaactaactg
     2341 gttcaaaggt gaaattcaaa aacgccgtga ttcgaaatag cgcaactaat agcagtggaa
     2401 cgccatctac tatttctggt actggcgctg aaggaattga gatcccagca gatcaggcag
     2461 tagatctagt aactgcagga gcaaatgaag ggattggcac atggatttat tcattaggag
     2521 agaatgtgga acaagggaga caatcagtgg aattatttgt tcctgtatcc aattatgccg
     2581 tagacaacta cgtttcaaca ttcacatggt cgttaacaga tgctcctaca gaagggaaag
     2641 cgtaaaatca aatcaatgac ttcagggagt ggagccgatt caaggccaac tccctgaaat
     2701 ctgctatgct tacgtctcag ctcttattca tcaactcgaa gcagtttttt ggaagtcatg
     2761 gaaacgttcc tttgtctttt caaagatctt tcgaccaacg agtaaggagt caccattgaa
     2821 aaattctaac acataatgag cagaatcaat tttctgcaat tgcgataagt tgatacagta
     2881 agattttaat agtaaaaagt aagcatactt ttccaactct gtcttcaatt gttttaaaga
     2941 agtattcact aatttatctt ctgtagttgt tttgaccata acttggtttt tcaaaccttt
     3001 gatactttca atatataaaa tttcccgagg atacaggacg agacttccac ctttttgatc
     3061 aataaagatt ttatcgacat ttacgatttg ctgttctttc caattgatct gttctagcac
     3121 ttgacgaatt tgttcagata aattcctgtc ttttctgata tatccaatcg gaaggatttt
     3181 ccgattgatg atctctactg caaaattcgt ataagcggtg aaaaaaacaa tattactatg
     3241 tgcatttttt ttacgtattt gttcggcgac atcaatacct gtgagtgatt gcttcaagtc
     3301 gatatcgata aagaaaacat cgtgattatc aatagtaccc aactggatca actgattgat
     3361 ttgagagata gaagtgagct gcacgatatt ctcgatatga tgattgacca attctttgat
     3421 gatccattcg ctgtgaaact ggttatcttc tatgataaaa tactttttca tatgcaggct
     3481 cctattaaaa aaatatgtgt acattttgaa acaaaacaat ggaggaataa gatggtcgca
     3541 acagtgacac tttatttgac ctttactttg attttagatt taggtatcta tttattcttt
     3601 tcgaaacaac tgctagtaaa aaacagcttt ggttttatag ctttgatggt ggtgacactt
     3661 ttatttccta tccctaaagt gagctttcct tacctagttg gcttattatt gatgtttctt
     3721 ttttatttta ctacgaaaaa cctgtttatc agctgtttga tcagtaatct tttttttgct
     3781 atcactggac tcagcttttt tctggttttt gatctgatgg attatttagg aaagagacat
     3841 cttggaacag caagtttttt tgcactactt atcgcattta ttttctatct attagtaaaa
     3901 agtatagaca aacagacgag atttctcaac ttgcttttta cttatccaac tgaacactat
     3961 tttggaggta tttgtatttt attaagctgg ggcgtgattt acttggtatt gggaagtgtt
     4021 cacttccgct catctaatta tctgcttcta tctcttttgt cgatagtcat cagttttttt
     4081 tctttgtttt tttccattat gttgatcagt ttccaagtaa aagaaagaca acatcaggaa
     4141 tcgcttcaac tgtatcaaat aaatgaagaa tattaccatc atctagagga attcaaacat
     4201 gattataaaa gtctactgtt ttcattaaaa attactcttc aggaaaataa aaaagaaacg
     4261 ttggaatttt tagaaatctt agaagatcat tctgcagcta tttttgaaaa accgcaaata
     4321 caacagctaa caaatattgt atccccagct gtcaggggtg tctttttaaa atttctagaa
     4381 aaagcagaat cggagaaaat cccgatccaa gtagttattc ctgtcgaagt gaaaacaatc
     4441 ccgattgatc tggttgtttt tattcgctgt ttatctattt ttatttctaa cgcattcgat
     4501 catcgtgtag ccgatcagag tccgattacg atcaatctgc tggaagaaaa agagggatta
     4561 cgttttagta tagcgaacaa ggcaaatccg acgaatttga cgctatcgga gatggtcaaa
     4621 agaggaaaaa cctctaaaaa aaatggcggg ttaggtctat acagtgcgaa aaaaatgttg
     4681 gatgtttacg aaaatgcaga actaaaaatc gaattttcaa aacagaatca ctattttttt
     4741 gtagaaatgt atctggcatc tagaaagagc aaatcagcct actgacttac tgtcaaagga
     4801 taagcttgag gaaagtctac acggagatag agacaacaac acagcatatt caaaagaaac
     4861 agaagcgtga tgaccgttgt cacccttctg tttcttttgc tatgtagtta aacaaagtag
     4921 ttgacacttc cgctacttag tattagtacg aaagtatact tcatgatact aagtagataa
     4981 gaagtgaaaa gcggaaccca cgatcgtcaa aatgctaact gctttgctta caccagataa
     5041 agggaagagc aatatcgctt attttaggcg tggagaagca agaaaatccc tacgatcaca
     5101 caaaaaatgc tgacccagca gttaagagag ttagaacaag atggcattgt ccatcgaaaa
     5161 gtctataacc aagtcccgcc taaagtagag tactcgctca ccgaagaagg aaaatcatta
     5221 agagagattc tagtagcgat gtctgtttgg ggagaagaac gtatcgaaaa acaaaaagcc
     5281 tcaggggaag aagtcacatt actgcataca catggtggct acctaaatta ctgatttcta
     5341 tgacatttat tttaaataaa agaaaacagg agttttttta aaagcatcat ctatttttta
     5401 tgtaaaaaaa tggtatgatt aatcaagtaa gaaatgattg gaagaaggca agcaaatgaa
     5461 tagcatggaa aaagttaacc agtttagaga tgaacgtaat tggcgacaat ttcataacga
     5521 aaaagatttg gctatttcta tttctttgga agcatctgaa ttgttagaac tttttcaatg
     5581 gaaaacgccg gaagaagtaa aagaaacaca attagaacga atcaaagaag aactggcgga
     5641 tgtattgatc tattcataca tgatggcaga caaccttcag ctggatctag atgagatcat
     5701 tgaagaaaaa ttgatcaaaa ataatttgaa atatcctgta gaaaaaagcg caggtgtacg
     5761 aaaaaaatac acagagtttt agaaatgtgt cattcggctg ttggaaagag caaaagaaaa
     5821 acagtaaaat gagtctggag ggagagaaaa tgaaaaaaaa aggaaaagca aaaagatggc
     5881 tagtcaatat cctcttgttc ctcttgttat tagtaggact agctttgatt ttcaatgaac
     5941 agatcaagga ttatcttgtc agagagacag gagataaata tgctatagcg aatgtaacaa
     6001 aagaagatct gaaaaagaat aacgataaag atgtcagttt tgactttgat gcggtagaac
     6061 caatgacgac agaaggggtc atgaggtcgc agatgagagg aacagatcta ccagtgattg
     6121 ctagtatcgc agtcccttca gtttcaatca atttaccgat tttcaaaggc ttggataata
     6181 cgtcactact ttacggagca ggaacattat ctccagatca agaaatggga aaaggaaatt
     6241 atgccttagc aagccatcgt gcaacgaacc ctgaattgtt gtttacaccg ctggaaaatt
     6301 tagagatggg tgccaagatc tatttgacag atttagaaaa tgtgtataca tacaaaacat
     6361 tttttaaaga aaaagttgct cctacagata cccaattact gaatgaagtc gaggaaaaag
     6421 aaattgtcac actaattact tgtggcgaca tggacgccgt cacgcgacta gttgtacaag
     6481 gagaactgga aagtgttaca ccgataaaag atgcgacaga tgatatgaga tctgctttca
     6541 atctagagac aaaaacattt taggatactg ggacataagt cgttacagat taaaaacagc
     6601 caaaggatat gaatcgataa ggaaaaacca atttgctgaa aaaaagagga acgcaaagag
     6661 gtgcatctct gatttggttg ttttctagat agacttgtgt tccagttttt ttatttttta
     6721 tatgaaaagg cttgcataaa taaaaattcg atggtatgat gattttgaat aagaaatgga
     6781 ttgttactgt acggcaggca aaaccagaat tcagctaaga aacagtaggc gaattctagg
     6841 tttttttatt tttcttgaga gggcgaagca aaatgaaaat tgataaaatt ttgaataaca
     6901 atgtcgtcat ttcgaaaaat ggattcgggg aagaagtcgt ttgtatggga aaaggactag
     6961 cttttcaaaa aaaagattgg ggacgagatt tcgccagaag cggtccaaaa agaatttatt
     7021 ttaagagatt cttttgctaa aaaccaattc cagcagctga tggctgatat tccggcagag
     7081 gagatcgaat gggtcaaaca agtagtcgaa ctggctgaag ataaactaaa agttgaattt
     7141 tcgcctaata tttatctgac attgaccgat catcttcatt atgcgatcac acgagcaaaa
     7201 gaaaatatcc aactgcctaa tccattatta tttgaaacaa aaaaatttta tccgaaagaa
     7261 tatcaagcag cgaaagaggc tcttttgttc gtgaaacaaa agacgggtgt ggaactttct
     7321 gaggatgaag ccggttttat tgcctttcat tttgtgaata gccaacaagg aaacgaagac
     7381 atgcaagtga cgatgaccgc taccacaatg gtaagagata tactgagtat catcagtaaa
     7441 ttcttcggca tcgtgttcga tgaagaatct ttgaattatc agcgtatcat tactcatctg
     7501 cagttttttg cccagcgtta tctcaaaggg gaaggatctg acgagcaaga tgaatttctc
     7561 tacgcattag ttcaaggaaa gtatccaaaa gcgtttcatt gtgtcgaacg gatcaatgag
     7621 tatcttcgac aaacgcaaaa acaggaaatg gggatcgcag agcagattta tttaacgatt
     7681 catattcaaa gagtagtaag tgagaaaaaa agcatccaat cataaggatt gttactgtat
     7741 ggcaggcaaa acctggattg aaaaaatagg ttcacgaatg tttgtgactg tttttttcaa
     7801 tctgggtttt tattttttaa ataaaaaaga aagaaggaaa aaacaatgga taatcaagca
     7861 gttggtcgtc gtgtatggga agcggtagga ggacaaaaga atgtcaaaag tttagtacat
     7921 tgtgctacgc ggttgcgatt cagattaaaa gatgaatctt tagcagatac gcaaaagtta
     7981 aaagaagacc cggacgtgat ccaagtcgta caaagtggcg gtcagtatca agtagtgatt
     8041 ggcagtaatg tagcagatgt ttatcaatcg atcgtggatg aggaaggtct tgcagtttcg
     8101 gaggatggaa aagaagagtc caaaaatatt ttgaatcgtc tgatcgatat tatctctagt
     8161 atatttacac cttttctagg ggcgatggca gccgccgggg tattgaaagg attcttatca
     8221 ttggcaacgg tgatgggctg gctgacagct gatagcggta cttatcaaat attgtttgct
     8281 gcagcagatg gtgtctttac cttcttacct gtcatgcttg cttttacagc agctaaaaag
     8341 ttcaaagcca accagttttt agcagtagca attgctatgg cacttgtgta tccagctatc
     8401 acagcagttg ctggtgcggg agaagctatc agtttctttg ggatcccagt gattctttca
     8461 ccatctggtt atacttcttc tgtcatacca atcattctag ccgtatgggt tcaaagtaaa
     8521 ttagagccat tcgtaaaaaa agtgattccg caatttctgc aaatgatttt agttccgctt
     8581 gtcgttttag tagtgatggt tccattaaca tttcttgctt taggaccaat cgggacggtt
     8641 gccggtaatg ctttaggcgg tctcttcaac tcgatttatg gatttagtcc aatcgtagca
     8701 ggtctaatca tgggaagttt atggcaagta ttcgtgatgt tcggcatgca ttggggattc
     8761 gtaccgatca tgtttttgaa tatcgaacaa tatgggtttg atgtattgat gccaatgctt
     8821 cttccagcca tcttggcaca aggtggggct gctttagctg tagcattgcg aacaaaagat
     8881 acgaaacttc gagcattagg gatttcttct acagtgactt cgttatttgg aatcactgaa
     8941 ccaactgtgt atggtgtgac attacctttg aagaaaccat tcattgccgc ttgtatttct
     9001 ggaggtattg gtggagctat tatcggattt tccggagtaa aagctttctc cagcagtttg
     9061 gtcagcttat tgacgattcc gactttcatt aatacggtgg atggtgtaga gtcaaatgtg
     9121 acagtagcag taatagctac aggaattgct tttgttcttg cattcgtagg tacattgatt
     9181 ttaggatttg acgaacaaac acaagacaat caattagaaa acaaacatgc gaatgcagga
     9241 gaaccgatta cttcagcacg gcatacctta aaaagtcctt taacgggtaa agtactgcca
     9301 ttgagtgaag taccagacca agttttttct tctggcgtga tgggaaaagg tatcgctatt
     9361 gatccagaag taggagaact agttgcacct gcagacggag agatcacgac tatttttcca
     9421 actggacatg ctgtagggat cacaacgact gacggagcgg agattttgat tcatatcggg
     9481 atggatacag tagaattaaa tgggaatggc tttgagatct tagtcaaaca aggggatctc
     9541 gtcaaagcag gagatttatt gattcgtttt gacatcgaag caattagagc agctggctat
     9601 agcgtaatca ctccagttgt cattacgaat actgatgcat ttgccgatat acttgaatta
     9661 gaccaaaaag agattattgc aaacgaagat gttctggcaa ttgtaaaata aggaggaaat
     9721 caggatgcaa tcacgttttt cagaaaaatt tttatggggt ggagcaactg ctgccaaatc
     9781 aattagaagg ggcttatgat cgagacggaa aaggactatc cgttgcagat gctatgcctg
     9841 gaggtaagca gcgctttgcg attatcggca gtgaagaatt tgactggacg attgatcaag
     9901 aaaaatatat ttacccgaat catcgaggaa tcgatcatta cgatcgtttc aaagaagatc
     9961 ttgccttgtt tgcggaaatg ggattcaaat gttatcgttt ttcgattgcc tggacacgaa
    10021 tttttccaaa tggagacgaa ggtactccta acgaagcggg attagaattt tatgatcagc
    10081 tgattgatga gtgcttaaaa tatgatattg aacctgtgat cacgatttct cattacgaaa
    10141 tgcctcttca tttggcaaaa gaatacggtg gctggaaaaa tcgaaaactg atcgacttct
    10201 atgaacgatt tgctcagaca gtattagaga gatacagcag taaagtcaaa tattggatga
    10261 ctttcaatga aatcaattcg gcctttcact ttccagcttt aagtcaagga ttagtaaaaa
    10321 gcaatggagc aggagagtac caaaatattt tccaagcatg gcataatcaa ttcgttgcaa
    10381 gtagcaaagc cgtaaaaatc ggccacgaat tgcgttcgga tatccaaatc ggctgcatga
    10441 ttatctatgc aacaacttac agcatcgatg ccaatccagt caatcaggca gcaacaatga
    10501 tccaaaacca agaattcaat tttttctgca cggatgtcca agtacgtgga gaataccctg
    10561 catacacagc gcgtacccat aaaaaatatg gagtcgatcc ggaaaaatta gagcaaacgg
    10621 aaaaagactt ccagttgcta aaagaatatc cagtggacta catcggattt agttattata
    10681 tgtctacggc aatcaatgag actgatccac aagcagcaac ttcagaaggg aacttgctgg
    10741 gaggagtaaa aaatccgttt cttgaggcaa gtgaatgggg ctggcagatc gatccagaag
    10801 ggctgagaat cgcattgaat gaattataca atcgttacca gaaaccatta ttcattgttg
    10861 aaaacggtct tggagccatt gatcatatgg aagaggatgg cacgattatt gatgattatc
    10921 ggatcgatta tttacgtcgt catatcgaag cgatggctaa tgcagtagca gacggtgtag
    10981 atttgatggg ctatacgcct tggggatgta tcgatcttgt cagtgcatca acaggagaaa
    11041 tgagtaaacg ttacggcttt atctatgtgg atctagacga tgaaggaaat gggacactga
    11101 atcgatcaaa gaaaaaatct tttgattggt ataaagaagt aattgcctca aatggcgtaa
    11161 acttgtaatt aaagcagctg aatgaaaaag aacacacttc tcacatgtga tttgtgttct
    11221 ttttctattt tttatgtgct attcttttag taatagtaaa gcaaagggtg acgttatgaa
    11281 aaggacacgt gtactatact tggaagtcgc agataaaatt aaagaagata ttttctcagg
    11341 aaaatatcca gtcggttcga tgttgccgac agaaagtgaa ttagaagaac tgtttcaagt
    11401 cagcaaaatc actgtccgaa aggcaatcga actgctggca tcagatgaat atgtcgcaaa
    11461 gaaaagtggt cgtgggacga cggttctaag caatcgtcct tacaatcgat tatccaaagc
    11521 ggcaagcttt acgcaaatct tggagaactc ccgatatgaa gtccggaaag aaacgctgga
    11581 tttgcaattg gtccatataa agaaggaaga tcctttgttt tcctttttcg gtgagcaagc
    11641 tgtttgtttt aagcgcttat attatttgaa caatcagcct tatatttatt ttgttcatta
    11701 tcttccacaa gaaatgatgc aattcagcag agaagaattt ggcaaagaat ctttgtatcg
    11761 tttgctgacg aaaaaaggat atactattga ctcattttct gatgatttct cggcagtatt
    11821 tttaacagaa gaagaacaag gaattctgaa aacagacgca cagatcggca tcaaacggat
    11881 acggaaatcg tctacgcaaa ttggggaaat gattgaatat tcggaggcgg tctaccatac
    11941 ggagctgcat ccttaccata ttgattatga aacataaata aaaaaagagg ttgtgaaaaa
    12001 gctgccctgc atcaagtaat aagaacagcc aaacaaaaat agcttctcat atttttcgtt
    12061 tggttaggct tattaccgca gatacacggc tgtttctgga ttaccattta ttctggataa
    12121 gggggtgtgg cacgattttc agaaggaatc tatgaaccaa tcactgtatt gattttagct
    12181 tcgatggtaa ccccattcgg cttgacgatc gcttatttct tagggaaaat cattcgtaaa
    12241 aatatactca atcgtcaaga aatcgataca ttgaagaccg cttttcctat ggggatctgt
    12301 cagatcacag agggatgttt ccctatcgta ttgaacgact tggcacgcaa tgtcatagca
    12361 acgggagtcg gtgggacagt aggtggcgga ttaagcatgt tttggggcgc agatagccgt
    12421 attccggcat cgggaatgtt tgcagtcgct acgatgacca gaccatgggc attcattggt
    12481 gcattgttag ctggttcttt tgtcacagga ataaccattt tattattgaa aaaaccagta
    12541 gatccgaatg cagaaatcat ccaagaagaa aaagaggaag aagacatatc ttgggatgat
    12601 ttgacaatta gttaggagag gcagaatgga ttacaagaaa aaagtacaat agatgtacct
    12661 tgagacagga atggtatgaa agaatcagag ttagaaagaa tcgaatatac agattttggt
    12721 ttaggagcga tcgaaactgt ccagagcatc ggcaccctcc ttgaaatgac gatgaaggaa
    12781 aaatgagaac ctttcgttgt cgaaagggtc tggtatacct tatgtcgaag gaaaggaaac
    12841 aaaaaaactt tcctgtacta ttccaaaaag gaaagaaagt tattatacag taaaaaaaga
    12901 aattattctt catgctagag atcagtacac gttcgagccc aatatcaaac actagttcca
    12961 ggcaggcgca acaggtgcgg ttatcactga attttcttcc agcagtgacg attcaagtga
    13021 tatttttaca aatccagcta tttatcgtta acaaaaagat ttttaggaga agctgatgaa
    13081 caaaaatgat caaattttga tcgtttagtt cgtcggcttt tttatttaga gaaacatcat
    13141 ttatcagtga aacataacac gagaacaaaa tgattttttc gttaataaaa gaaacaagta
    13201 tttgttgttt aaaataatac acgttattgg catataggac gaaatcccag tatcttctat
    13261 aagtaagtca tttcatatcg atgaaaacac gttatttatt tttgttttat ctataaaatg
    13321 gctgaaaaat gatttttttc taaatactat atatagtggc gtctatccta tataccacta
    13381 aaaaactaca aaatctagtc ttttatttta aaaaaacacg tgtagaatga agatagactt
    13441 ttgagttagg gagtgttttt ttatgaaact tactgttttt tgcggttccc gttttggtaa
    13501 taaagaaagt tacaaattta ttgcgcaaac gttaggaaaa tacatggcac aagaagaaat
    13561 cgaactggtt tacggtggtt catactccgg gattatggga gtgattagta aaacagtact
    13621 ggaaaataac ggaaaagtca caggtatcta tccgaatggg ctttttgaaa ctgaattgcc
    13681 tggaaaagat gttactacat ttattcctac agaaacgatc gatgaaagaa aggtattatt
    13741 atttgaaaag ggagatgctg tcctcgtttt ccctggaggt ctaggtacat tggaggaatt
    13801 ctcacaactt ctttcttgga tagcaatcgg tctgacgccc gacaagccaa tcggaatatt
    13861 gaatattggc ggttattaca gcggcttgca acaattatta gaaacttttg caaaagagga
    13921 ttttatggat aaaaaatggt tggatcaagt aatcttttcc aacaatccat tggaactggt
    13981 caatgaatta cgagcagtat ctattaaaaa tcagttatta ttgaaggagg caaaataatg
    14041 agtcaaatat atttagcagg accatttttt tcagaggagc aaatcgatcg agtaagtcgt
    14101 atcgaaaaag cgttggagga aaacaaaaca gtcacaagtt tctactctcc acgtcatcac
    14161 caagaaagca attatgaact attcagcgct ggatgggcgc aggaagtata cgaaaaagat
    14221 atggaagaac tgacaaatgc agaatttgtt gttgctatcc ttgactttga gcatcaaaca
    14281 atcgatccag gaacggctta cgaattaggt gtggcaacta tgttgaaaaa accgatgatc
    14341 attgtacaag aagagacggt acctacgaac ttgatgatta cacaaagtct ccatacgtat
    14401 ttaaaatcag accaagctgt acgtgaatat gattttgaaa cattgcctgt tgaaacttac
    14461 gtaggcgagt acttatagaa gaggaagggt tgtatgtcag tgattttgat ttcaggaacg
    14521 attggtgcag gtaagagcag tttgacggat atgcttgcaa aagagattga ttctaaacca
    14581 ttttatgaaa atgtcgaaga taacgaagta ttgccgctct tttattcaaa tcctgagcag
    14641 tacgcttttt tattgcaaat cttctttttg aacaagcgat ttttagcaat gaaaaatgct
    14701 ttagtgaacg atgacaatgt gctagaccga tccatctatg aagatagcct gttgttccat
    14761 ctaaacgctg atttaggtcg ggtaacggat atcgaagtac agcagtacga tagcttatta
    14821 gatacgatgc taaacgagtt agatgatgtt gctccaaaaa aacggcctga tttgatggtc
    14881 catatcaaag tttctttgga cacgatgcta gaacgtatca aaaaacgtgg gcgtgactat
    14941 gaacagctag aaagcgatga gacgttatat acctattatg aaacgttgaa cacccgctat
    15001 aatcaatggt atgaagattt tgatgtatgt cctaaaatac aagtggatgg ggataaattc
    15061 gattttgtag aaaatccaga agatgcaaaa aaggtgatcc gtcagatcca agaaaaatta
    15121 gctgaattgg aaggaaagcc tgctggaaaa tattttacgg ataaccagca tgcaaaaggt
    15181 caagaattag gctaaaaata aaaaaccaaa cgacgggaaa gaaaaatt
//
LOCUS       DAFLWQ010000069        15192 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.072, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000069 DAFLWQ010000000
VERSION     DAFLWQ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15192
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.072"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..392
                     /locus_tag="L1V16_002121"
     CDS             <1..392
                     /locus_tag="L1V16_002121"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276448.1"
                     /translation="RDFLFSIYTKYFTLSSNIKTSTKLICKLFKLDKISNIDDVKSKI
                     LTRKVSEPVKLTAQDKKNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSGEKVTFKI
                     NFITAISKLEYGKQKKRDNNDQYLPKK"
     gene            473..1093
                     /locus_tag="L1V16_002122"
     CDS             473..1093
                     /locus_tag="L1V16_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276449.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            1794..2078
                     /locus_tag="L1V16_002123"
     CDS             1794..2078
                     /locus_tag="L1V16_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276450.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            2081..2998
                     /locus_tag="L1V16_002124"
     CDS             2081..2998
                     /locus_tag="L1V16_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1276451.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            2991..3773
                     /locus_tag="L1V16_002125"
     CDS             2991..3773
                     /locus_tag="L1V16_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1276452.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            3774..4454
                     /locus_tag="L1V16_002126"
     CDS             3774..4454
                     /locus_tag="L1V16_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1276453.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            4447..5343
                     /locus_tag="L1V16_002127"
     CDS             4447..5343
                     /locus_tag="L1V16_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1276454.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            5538..7187
                     /locus_tag="L1V16_002128"
     CDS             5538..7187
                     /locus_tag="L1V16_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBN1276455.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            7781..8716
                     /locus_tag="L1V16_002129"
     CDS             7781..8716
                     /locus_tag="L1V16_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1276456.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            8709..9479
                     /locus_tag="L1V16_002130"
     CDS             8709..9479
                     /locus_tag="L1V16_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1276457.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            9895..10878
                     /locus_tag="L1V16_002131"
     CDS             9895..10878
                     /locus_tag="L1V16_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HBN1276458.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            11325..12362
                     /locus_tag="L1V16_002132"
     CDS             11325..12362
                     /locus_tag="L1V16_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBN1276459.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(12451..12774)
                     /locus_tag="L1V16_002133"
     CDS             complement(12451..12774)
                     /locus_tag="L1V16_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBN1276460.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(12761..13468)
                     /locus_tag="L1V16_002134"
     CDS             complement(12761..13468)
                     /locus_tag="L1V16_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBN1276461.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            13554..13895
                     /locus_tag="L1V16_002135"
     CDS             13554..13895
                     /locus_tag="L1V16_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HBN1276462.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(14066..14914)
                     /locus_tag="L1V16_002136"
     CDS             complement(14066..14914)
                     /locus_tag="L1V16_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276463.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
BASE COUNT         4869 a         2590 c         3205 g         4528 t
ORIGIN      
        1 gaagggactt ccttttttct atttacacaa aatattttac actctcgtca aatataaaaa
       61 ctagtacgaa attaatttgt aaattattta agcttgataa aataagcaat atcgatgatg
      121 taaagtccaa gatattaaca agaaaagtaa gcgaaccagt aaagctaacg gcacaagata
      181 aaaaaaatgg aattgttctt tatggtgatg atgcaaagta taactataat tgggatacct
      241 cctcagaagc tgaggtatta agtattccta ctaccgatac ttcaggggaa aaagtcacct
      301 ttaaaataaa ttttataacg gcaatttcta agttggagta tgggaagcaa aaaaagagag
      361 ataacaatga tcaatatcta cctaaaaaat aacgaattaa tgatgcatat gttaaagttg
      421 tttttttgaa ttaaacaact caatttattc agttatatgt tcatcgcagc aagtgaacat
      481 taatcgagtt ataaaattaa taggagctaa aaatataaat aaagttcgat cagaatttat
      541 ttttccagaa gattttttta actggttttt ttatcaattc agtgaatgca agcgactctt
      601 aggtgagaat tattacttaa aaggaatcgg cggatttatg gggaatgtgg ctgatgaaca
      661 aaatattata aaaggaatat ctgaacaaac atcagagctt acagtaacta aagcatttat
      721 aagtaatggt gaaagtttga aaaatgtaac tgcgcgaatt agaaaagaaa atgaagtaga
      781 cattgttttt ggaattgacc atgaatgtaa ttcagtgata tatgtaacac aatcagcaaa
      841 tttaattctt tttgagaatg gttgcaagga cgattttatg gtggtctatt tgtacgatat
      901 actaattcca aaacttcgtt ccttatatat gtcttctgaa agtatttttg tgagtgaaca
      961 aaagggatct ttctcgaaaa aaataggtat tgaagtaatt gaatcgatta tgtgtcataa
     1021 tcatattacg ctagaagaat tagaaatttt gatagggcaa aaaaataata acacgaaaat
     1081 acaagtttct tagaaatcat tttttattga gatatctaga taaatgattt attcttcaat
     1141 caaccaactc gccaagctga ggtaatgttt tgaggtaatg ataacataca actttttata
     1201 ccctagtaaa actctataaa caaagactta ttaatttcgc atgaaataca ttcctgtaaa
     1261 atgcaataaa atagagtttt gtttaaccag gtcttaagaa agcccgtaaa gcttcacagt
     1321 tctcaaaacg ttaattgcga ttatcgttcg agttcacgag ttacgagaat cgtactgggc
     1381 gaagcaatgc tgagcgcagt taccttaatc ctaacttttc tggcactttc cacaatttgg
     1441 aaagtgcctt ttttgtgttt ttagctatgt taataggtag gattcttggt ctataatatc
     1501 attcgatcta taaacaaacg ggaaaaagat aaagtatcat caaacaatat tatttatccg
     1561 cttctgaggt tgtgacagaa gtggtcagct tcaagaaata agaaggaatt tacaaaaatt
     1621 gcttctcatg tttgataaat attgtgactt gtgaccgagg agttggcagg agaacaccgt
     1681 ttattcggaa gaagggattg tgaaaagtct tttgtcataa cctcttattt ggtagctaat
     1741 tgtaaatccc aaacggcatg tattattttt cataagtccg tttttaagga ttaatgtttt
     1801 cttttgcttt ttatatggtc tggcttcagc gagaagttcc aacgcatata caaggacgtc
     1861 tgatgtcaac gataacaacg attaccatgg tggccagtcc acttggatta gcactgtttg
     1921 gtgcgctctt tgattggcag acaactcaac cacgtctgcg agacagtctg atttttcttg
     1981 aaattcaatt ggaaaattta cactttcttt atacatttct ggctgctttc tttatacccg
     2041 tcaactatac ttcacttatc aataagaaag aaggataagt atggattttg gaaatgaaac
     2101 ggtcttgaaa gcaactggta taaccaaaaa atacggtgct gccaaagcat tagataaagt
     2161 atcgatcgaa atcaaacgtg gaatgatcta tggtttgatt ggggagaatg gagcgggtaa
     2221 gtctaccttt atgagaacta ttatgggttt gatctcgatt gatgaaggtt cgatcgaatt
     2281 atttggaacg acggatttgc aggcagcaag acgacgtatg ggtcaatcga ttgaaacccc
     2341 tgctctttat ccagaattaa ctgcaagaga taacctacgt atccaagcag cgaacggcgg
     2401 tgtgtcggat agagaaatcg aagacctgct gaaaatgatg cgattggaaa atacagggaa
     2461 aaagaaagca aagaatttct ctttaggtat gcgccagcgt ttagctattg caaatgcact
     2521 gatcacgaat ccagaatttt tgattttgga tgaaccgacg aatgggatgg atccagcagg
     2581 gatggcagaa atgcgagaaa tcatccaacg tttggtaaaa gaacggggca tcaccgtctt
     2641 gctttctagc cacttgctag atgaattgtc acagatcgcc actcactacg gtattttgca
     2701 tgaaggacac ttgatcaaag aattatcgaa agaagaattg gcacaagaat ctcgtcaatt
     2761 tataaaaatt gacacttcgg cgacggaaca agcagtaacg gttctcgact ctcttggtta
     2821 tagggattat tttgtccaat ctagccgtgt tatccagctt tttgaaggaa ttgaccaagt
     2881 agcagccatc aatcaagcat tggtagaggc aaaagttcct gtggatggta tccacctagt
     2941 tgggcaaaaa ctggaagatt atttcttaca attaactgga ggcaatccac atgtttaatc
     3001 tattaactgc tgaaaaaata aaagtatgga agagccgtaa aatgtgggtc tcactaggac
     3061 tgatggtcgt acttccgctt ttttattctt ggaacgaatg gtatatgcat acaaaatacg
     3121 gcaatgaatt aaaccaagca acggatacag tcatcaacgg tgcaacaggg attttaatgg
     3181 tggaaaaaat ggctgcatgg attcttctgg ctttcgcagc atttgcgtgc ttttatattg
     3241 gggaagaatt tcaaaacggt acgattcgca atacgttatc tttaggacgg aatcgaatga
     3301 cttattatgt gtcgaaactt ctcgttacgc ttttgatcac aacacttggc gtggttttga
     3361 ttacggggct agccatgatt gcttacacac ttgctttcgg atttggtgaa gttgagggaa
     3421 tcaaaaacta tggaaattat gttctaaaag tatttcctgt attgcttctg ctgatattag
     3481 cgacattatc tgttccagtg gctttgacat tcatcactag aagtaccagt gtcagtttgc
     3541 ttctttcttt tctttatatc atgggaacgg ccttcgttcc cggtgttttc gcaaaaatca
     3601 aaggcttgga atttctaacg gagtggttta cggaaacgtg gctcatgtat acggactttg
     3661 cgcaacaagc aacttattcg caagcaccga aaatgattct ggtcagtcta gtaacaatcg
     3721 tggtatcatc agctctagga atgtttattt tccaaaaatc tgacattaag taggtgttcc
     3781 tgctggaaac tattttgatt atcgaagacg atgaagctgt tcattcttta ctggaggagg
     3841 ttcttgaaca gagatacaaa cttcttgatg cttattcagg tacggaagga aaattattgt
     3901 taagcacata tcctgtcgat ttgatccttc tagatctcat gcttccaggg ctttcaggtg
     3961 aagcattgtt agcagaaatc cgacagacat cgaatgttcc gatcatcgtt ctttcagcaa
     4021 aaagcgatca aagagataaa gtttccttgt tggcagcagg agcggatgac tatgtgacga
     4081 aaccatttga tatcgaagaa ctgttgttac gaatcggcat ccaacttcgt catcagactt
     4141 ctgtccaagt aaaagatctg tcgcaacgca tctattacaa ggaaatctta ctggacaaag
     4201 agtcgaggga tgtaaatgtg aatggtgtgg ctgtccattt gacaggaaga gaattcgatc
     4261 tgctgaagct ttttttagaa catccgaaaa aagtattttc gcgagcaaat ctttatgaaa
     4321 cagtttggca agaaccatat tttgatagtg agaaaacagt gaatatgcat atttccaatc
     4381 ttcgagggaa actagcaaag gcacatgctg tgtatattca tacggtgtgg ggagtggggt
     4441 ttagatttga ttaagtggct gttgcttctc gttgttatct ttatgggaag ttttattttc
     4501 ttcctgcaaa gggaaatcaa gagattaact aagaaaatcg ccactctttc tgaacgacaa
     4561 gaatatggtg gtcgtctttc agtcgaattt cgagaaaaga atctaatgga cctagtagat
     4621 gcactgaata catgggtgga tgaaaatgaa caaaaaggac aagcatttca agaaatggaa
     4681 gaaaacatca gactatcgat cgtcggcctt tctcatgatc tcagaactcc tttgactgct
     4741 attaacggtt atgtacaatt actggaacag gtagaggata cggagaaacg ggagaagtat
     4801 ttaacgatca tcaaacaatc tgttgcaaga ttactcagta tgacggatca gttttatgat
     4861 cttgctcgaa tagagacgaa gcaaaaagaa atggatctcc atacgctttc tttttctaaa
     4921 gaggtggaag aagtattttt ctctttttat gaacaatttt ctgagaaaaa tatcgaggta
     4981 gcgttcgctg aacactcgat aaatacaact gtattagcag atccgctcat gttgctgcga
     5041 gtgctgcaaa atatcataca gaatttattg cgttatgcag atggacaagc aaaggtgaca
     5101 ttttcaaaag aggattcatt cattcgatta acagtggcca atcctatcaa accaggagcg
     5161 caaacctctg ttgaaaaagt cttccagcgt ttttataccg aaaataccag ccgcacaaat
     5221 acggaatcta gcggaatcgg gctttacctg tcaaaaaaat tggtggaagg aatgggagga
     5281 gagatgaccg ctagattaga cgggggcatc ttctccatct ccgtcaagtt gcggagggtt
     5341 taattggctc taatttacct gaagtgaatg acaaaaaatt gtatctcgtt ttaaagacat
     5401 cttctttttt ggaaggtgtt tttattttgg tgtgattgat acgaattagg taacgaagac
     5461 agttattttt gtaccccctt ttcaaatagc gcaacagtgc tatactaaaa ctaacaaatc
     5521 aaggaacgga gagggatatg ggccaaagag aatttatcgt tttaattatt attgcagttg
     5581 ttattttatt agttgtttta gacatttttt cacgtttgaa agtaaaggaa acagttcgta
     5641 gtaattgggg aaaaattcct tatcaaccga gatttgataa agaagaaagt ttgaaggatg
     5701 cgtggctcac ggagaaaaaa ttccgttcat gggatagtga aatcgacgat cttacttggt
     5761 atgacttgga tatgttcgaa gtatttgaag ggatcaacag tacctattct agtgtaggtt
     5821 cagaagcgtt gtatcagcgt ttacgtagct ttgattttgg agaagattat cagttagaaa
     5881 aactaattgc tttttatcag gaaaatcctc aactgagaga aagaatccaa tatcaattcg
     5941 ctcgtttagg aaaaaaagat cataattttg caaaacaata tctagcggat ggaaaaagta
     6001 aaaagattgg acgcgtaggt ttatttattt ttcttggctt gcttccgctg gtgggtgtag
     6061 gtttgcttct tttagggcaa gtactaggaa tctatctagc aatcggtggc ttagtattca
     6121 atacggtcta ttatctagtg aagaaacaaa cactagaaac agagctgaat agcatgagtt
     6181 atttggtttc aacgatttca gccgccaatc agttagcaaa aatgacgaca ccacttcaaa
     6241 aagagctgaa acagcaaact aaaccattaa gagacatccc taaattaggt ttttcatttc
     6301 gaatgaagag cgggagtgaa gcagaattga tttttgaata tgtcaacatc atgttcatgc
     6361 tgccatttat ctcctatcat ttcgttctca ctaaattaga aaagcattca actgaagcca
     6421 tcaagctgtg ggaattgctg ggagaattgg aagttgcagc agccgttttg aattatcgca
     6481 cctatatgcc gatcacttgc cgaccagagt ttactgaggg cggtgtgaca gcgaaagata
     6541 tctatcatcc attgttaaaa gaagcggtag ttaatccagt caactggcag aagaatacat
     6601 tagtcacggg ttccaatgca tcaggaaaat ctacgtatgt caaaagtata gccatcagct
     6661 gtattctagc acagacgatc caaacagcga ttgcagaaca gtttaccctg caacctggac
     6721 atgtgttgac ttccatggca atcgaagatg atttatttga aggcgacagt tattttgttt
     6781 cagaaatcaa atcgatcaaa cgtttgctgg accaagtggc ttccaaagaa cgctgctact
     6841 gcttcgtaga tgagatttta aaaggaacaa atacgatcga acggattgct tcttccgctt
     6901 cagtcgttcg gtggcttgcg gagtatccat ctttagcatt tgtcgccaca catgatatcg
     6961 aattgacaga gattttaaag aattattgtg agaatgtcca ctttgaagaa caagtaacag
     7021 aaggaaaagg aatcagtttt gatttcaaat taaaagaagg accttcaagg acccgaaatg
     7081 cgattgcctt gctgaaagtt ttgaattatc ctaaatccat agttgaacag gcccaaaaag
     7141 aaagtttgtt gttcgatgaa cagcgtcagt ggtatccgtt tgattaactt tatcaaacga
     7201 agcatgatgc gtgggtccaa aaagacgatt atcaaaagaa gtacattgat gccaaaaaag
     7261 tggcagaatt caatgggaac gagtctgctg tccagatgat cttggaagat ttagcaaaag
     7321 acgatacaaa ataaaccacg ctgtcttcct tctagcagct tttatcgaaa aaacttagca
     7381 tcagcgacga gacgcacgtt ccatggcaaa gttctccgta aaacaaacag cgaaaacaga
     7441 aattgaaaat aactatttcc attttattta tttcggttaa aataaaagaa aaaagctttc
     7501 gataaaagga cggaggaaag cttaacatga ataaaaaaga caagaacctc agttataagg
     7561 atcttctata tgtcatcgta gtagttgctg tcggtacttt tatgatttta aaagttccag
     7621 agttgtttag atagttattc tatcgaagat gatcatgaac tagaaaacac atctcctctt
     7681 tgttagcagg tgtgtttttg tgtggaagcc aagttgtttt ttcatctgct gtattccatg
     7741 atacaattaa gaatcatgtc tataaggaga taggaaataa atggcaaatg cgcttgaaat
     7801 aaataatttg aaaaagatct atggaagtgg ggtcgaagca ttgcggggaa tcgatctttc
     7861 ggtgaaagaa ggagatttct atgcgctatt agggccaaat ggagctggga agtctacaac
     7921 gatcgggatt attacttctt tagtcaataa aacatctgga aaagtgaatg tcttcggtta
     7981 tgatctggac aaggatctag ttcgagcaaa gcaacagatt ggattggttc cacaagagtt
     8041 caattttaac ccttttgaaa cggtccagca aatcgtcgtg aatcaagcag gctactacgg
     8101 tgtctctcgc aaagaagcga tgaaacgcag cgaaaaatat ttgaagcagt ccaatctttg
     8161 ggaaaagaga aatgtccgtg cacgtatgct ttccggggga atgaagcgaa gactgatgat
     8221 tgctagggca ttgatgcatg aaccacgttt gctgatcttg gatgaaccaa cagcaggagt
     8281 tgacatcgag ttgagacgcg agatgtggga gtttctacga gaattgaacg aaaatggtac
     8341 aacgatcatt ttgacgacgc attatctaga agaagctgaa atgctttgtc gcaacatcgg
     8401 aatcatccaa tcgggtgaac tgatcgagaa tacaagtatg aaagagcttc tgtcaaaact
     8461 gcaatttgaa acatttatct ttgatttagc gccatatgat accaaacctg tgattgaagg
     8521 atatgcttgt acatttgaag atgagcagac aatcgctgtc gaagttgaac gaaatcaagg
     8581 ggtgaacgga atcttcgatc agcttacaag acaaggaatc aaagttcttt ctatgaggaa
     8641 taagtcgaat cgtttagaag aactgttctt gaaaatcaca gaagaaaata atcatacgga
     8701 ggagaaaaat gtttaatctt tattttactg cattaaaaag tttagctatc aaggaaacga
     8761 accgctattt gcgtatatgg gtccaaacac tggttccgcc agtgatcacg acatccttgt
     8821 attttgttat tttcggaaaa atgatcggtg ggcggatcgg tgacatgggt ggtttttcat
     8881 atatggaatt catcgttcct ggtttgatta tgatgtctgc tatcactagt tcgtatgcca
     8941 atgtttcttc gtccttcttc tctcaaaaat ttcagaaaaa tatcgaagaa atcttggtag
     9001 cacctgttcc tacgcatgtg attatttggg gctttgtgat tggtggtgtg ggtcgcagta
     9061 ttctcgtcgg ctctctcgta acgatcattt ccttgttctt tgtaccactt catgtgtatt
     9121 catggttcat ggtcatcatt acattattga tgacggcaat cttgttttca ttagcaggac
     9181 tgctcaacgg gatttttgct cagtcttatg atgatgtatc gatcgtgcct acatttgtct
     9241 tgcagccgtt aacttatcta ggtggcgttt tctatgccat ctctatgtta ccgccctttt
     9301 ggcaagctgt ttcaaaagtc aatccgatcg tttatatgat ctccggtttc cgttacggat
     9361 tccttggaac gatcgatgtg ccagtagcaa catcgatgat cgtacttgtg ttattcatcg
     9421 ttgttttgta cgccgttact tggtatttga tcaataaagg aagaggattg agaagttaga
     9481 aaagaggttg tgaaatcagc gttttgacct gagtattaga gaaacaaacg ggaaaatagt
     9541 tcctcatatt ttgttgtttt ttgagcgaat accgagggtc agctgattga acaccgttta
     9601 gtggagaggt tgtgaaaaag ctgttctgca tcaagtaata agaacagcca aacaaaaata
     9661 gctcctccta tttttcgttt ggttggactt attaccgcag atgcaagctt ttgaacacca
     9721 tttattccgg aaaatggact gtgataagat ttttgtcaca gtcttttttt tgctcaatca
     9781 gaaacatctt ttaagctgtt cactttgctt ctttttttgt ttcctagtat aatgacaatg
     9841 tttttgagaa agattgcgac ttcactgctt gatagaatgg agagtaacaa ataaatgact
     9901 actaattttt ggaaagagct gccaaagcct ttttttgttt tagcaccaat ggaagatgta
     9961 acagatgttg tatttcgcca tgtcgtaaag catgcagcag caccggatgt cttctttact
    10021 gagtttacaa actcagacag tttctgtcat ccagatggaa aagacagtgt acgaggaaga
    10081 ttaacattta cagaagatga acagccgatg gttgcccata tttggggaga caagccagaa
    10141 ttttttagag aaatgagcat tgctatggca gaaatgggct tccaaggaat cgatatcaac
    10201 atgggctgcc cagtccctaa tgtagcagaa cgtggaaaag gcagtggctt gatccttcgt
    10261 ccagaagtag cggcacaatt gattgaagca gctaaagctg gcggtttgcc tgtcagcgtc
    10321 aagacgcgta tcggctatac ggaaatgtct gagatggaag aatggatcag tcacctactt
    10381 catcaagata tagccaatct ttctgtccat ttgcgtacgc gtaaagagat gagtaaagta
    10441 gatgcacatt gggaagtcat tcctaaaatc attgctttac gtgaccaaat cgctccacaa
    10501 acactaatca cgatcaatgg agatatcccc gatcgccaga caggagaaga attggccgag
    10561 aaatatggcg ttgatggcat catgattggc cgagggattt tcaagaatcc ttatgcattt
    10621 gaaaaagacc cgagggaaca tacagaaaaa gaactgatcg gactacttcg tctgcaacta
    10681 gatctgcaag atcattattc agaaatcatc ccgcgttcca tcacaggact acatcgtttc
    10741 tttaaaatct atatcaaagg atttccagga gcaaatgact tgcgagttca gttgatgaat
    10801 acgaaatcta ctgatgaagt acgagagatc ttagagacct ttgaaaaaga acatccaacg
    10861 cttttcagtg aacaatgatt tcttgcttga acaccgtgaa ttagaggtcg tgaaaaagct
    10921 gtcctgtatc aagtaataag aacagccaaa caaaaatagc tcttcatatt ttgtcgtttt
    10981 ttgagctaat accgagggtc agttgattga acaccgttta tatcagaggt tgtgagcctg
    11041 ccgtttaact ctgagtcaca aggagcaatt tcaaaaaaca gcttctcatg tttgatgaat
    11101 attttgactt gtgaccgaag agttggtagg agaacaccgt ttataagagg ttgtgacaaa
    11161 agtcttgtcg caacctcttt tttaaccaaa aaagtgcaaa tagtttactt taagtaagag
    11221 aataattatg atgaataaaa aaggtggaac aaatagcata ctatatatat tgaaatgaac
    11281 actgtatgga tgctccaact tgatgaagct aaggaggaat tcgtatgtca gaaaaggaat
    11341 taatgaaggt agtcggtttt tatgaagggt tgccgatcga tgatccaaaa agctttattg
    11401 atgaaaaaga acagatacct gtacccagtt cacgggatct tctggtaaaa gtcaacgcag
    11461 tatctgttaa tcctgtcgat acgaaacttc gccaagataa cgggataaga aatgctttac
    11521 gtatcttagg ttttgatgga gtcgggaaag ttgttgctgt aggtgacgaa gtgcaaaaat
    11581 tttctgtcgg cgatcgcgtt ttttacgcag gtacaacaac aagagcagga agcaatcaag
    11641 aataccaact agttgacgaa cgtattgtcg ctcttgcacc aaaaaatctt tcagatgaag
    11701 aagctgcagc cttgccgttg acctcattga ccgcttatga attgttattt gaaaaatttg
    11761 gtctaactcc agaagaaaat gccaatcgcg ggaaaaaaat cttagtgatc aacggatccg
    11821 ggggcgtcgg ttcgattttg aatcaactag cgcattgggc tggcctagaa gtctacgcga
    11881 ctgcaagtcc gaagaatttt gaatggctga aaaaaacagg tgtagactat ccaatcgatt
    11941 atcatcacga cttaagtaaa agttttcgtg aattaggaat cgatcaagta gagtatgtcg
    12001 ctgtattatt cgatattacc cgctactttg atcaaatcaa gcaccttgtc cgaccatttg
    12061 gacatgtggg aacgatcgta gggatcaaag agccgttaga tataggtgtt tggaaaaacc
    12121 aatctatcag cttcgactgg gagtatatgt tcgctaaaac agactataac tatgaaatcg
    12181 aaacgcaagg agaagcttta gcgcacattg ctgctttagc aaatgaaggg attatccgca
    12241 gtacattgag caaggtctat tcagatggga tgaatgcgaa gaacttgaaa caagcaacca
    12301 aagacgtaga aacaggacat atgttaggaa aagtcgttgt tagtggtccg ttcaacggat
    12361 aagcaagaat acgccgattt ttttcttatt tgactttgat aaaaacaaga gcgcatgaca
    12421 gtaatttgcc ataagctctt gtttttttat ttataataag cgaatcaacg aaagggaaag
    12481 aattcctgcc aagacgatca ccaataagct ttttgaaaga atagcagcta aaagtgtagg
    12541 aactgaagcc aaagcatttt cgagattgat ctgcggcaga tgtccgatat tttgggtaaa
    12601 tagactgctg aaccataaag cagacataat gacgatcggg acaaaactta aatactcaag
    12661 caacggttgc ggtaaatcga attttttcag taagacaaat ggtaggaccc tagaaagcca
    12721 agttgctaaa gtacaaccta aaatagtcag caatgtaaac tcaaaagaag gcatgtttga
    12781 tccacacccc caatccgcac ccaatcagtg ttacaactac aatcactaag ttgcttggga
    12841 taaaaatcag tccgacatat accagaatca aagtgagacc aatcaggatc aactgtaatc
    12901 gtttagaggt gtttctatca gaaatgactt gaagataaag taacccgata aacatagcga
    12961 cgatggcgaa atccaaacca aactttttcg gatcagtaat aaaattccct aaaagtgcgc
    13021 caacaagaga agaacccacc cacgtcaaat aagaaatcca attagctgta ttcatccaac
    13081 gaaagtttaa cttttgtcca gtatagttca atttattcat tcccagtgcg aaactttcat
    13141 ctgtcagcaa tgtgccaatc agcagatttt gaagcagccg atttttcttg aaataaggag
    13201 caatcgtcat actcatcaga atcattcggg aattgactag aaaggtcgag aaaacgatgg
    13261 aaagcaatgg gctgtgacta gcaagcatgc tgactgtgat aaattgggca gaaccagcat
    13321 agaccagcag ggacatcaac gtgacgacta gtggatgaaa tccggcagct ttcccaacga
    13381 taccaaatgc aagtccaata ccgatataac cgaaaacggt aggtaacgtg tctttgatcg
    13441 cagtttttat atctaacttt tcatccaata acaaaactcc tttagcacga cataaatttt
    13501 cataattgtc gttaaacttg tgaatattct aaatttttaa tgagcatttg tcaatggtgg
    13561 gattgaaacg taaagaacta gcgggtcgca gatttacacg tattgtttcg gtgggaggag
    13621 gcgcgaaaaa tcttgcatgg ctacaaatcc aagctgatat tttcgatgca acggtctatt
    13681 gtttaagtgt ggaggaagga cctgcattag gcgcaacaat gattgctgca ctagggttag
    13741 ggtggttcga cacacctgaa agttgttgtc agaattttat ccaatataca gatgcagtgg
    13801 aacctctctt acaaaatgta gaaaagtatc ataaaatcta tcaacaatgc cggaaaatct
    13861 atccagcaac gaaggaaatt tgtcatgact tataaaacaa aacgcgtacc taatagtcaa
    13921 atgactaata ttgggtacgc gttaagtctt ctttacttca tcctttgcat gattcgtgtt
    13981 tttaaagcaa ggtctgctgt atttcttgtg gatttaggat ggttgttatc gtttacttgc
    14041 tatttttcat tgaaatcgtc tttctttacc gtttctttag ttttttatct atttttttct
    14101 tttggttaga aaattctttt tcccgaaagt cttctttcag gatttttata gagtagcgtt
    14161 ttgaataaga ggcgtcagta tgatcgactt ggcagacgaa ccaagagaac atttgccttt
    14221 tttctgcatg aggtgcttct gctaataatt ctttccataa ataataacag tcctctatca
    14281 gaagaagggt tcgttcatcc tcaggctccc aatagaatgt ttcgagagta gcaatcactt
    14341 cattgatcaa ttcgaatgcg ggaagatagg cattttgctg aataagcgat tcaactgctt
    14401 cttggatgaa ctttcgcatc tccatgatga acttcgctgt tttcctgttt ttgtttttct
    14461 tgataatatg atcgtattta tggatgatag ttgttaattt atctgaataa tttattgcat
    14521 gaaatggcat cttaactttg aagcgttcga taaagtgcgg atgttctata agaatctctg
    14581 ttaaaagctc ccgtacaaga gaggaactag cggaggaaac aagggacgag agttcggaaa
    14641 gtgagtagtt ggattttttt attggacgtt cttcgtaagc gaataagaca gcagccatgt
    14701 gtttgcattt ttttccttct atggcatata gacaatcaca agtcatgttg gtcttttcat
    14761 cccaagtgat cactacctta taatcttccg tgccagaaac tgttgcggac aagtacttgc
    14821 ttgtatagtt caaatgacgg acaaaaccgt gcagatgata gctgtaaccg cgttccaaaa
    14881 cgttttcagg aaaatactca agccaattat tcatctagtt ctcctttcat gaaacactta
    14941 tttatattta gtataaagaa acgtttaaga aaaaagtagc tgattttaca tatttgataa
    15001 tcacttttgc tcgaattgtc aaaaattcat tctccttttc ttttcttaga gaatgtgaga
    15061 aaaagtaaaa gaatagcgtg ttttaaagat ggaacttttt ttgtttttta tttatctgac
    15121 aaaaatgaag tgattttgtt agaaataaat aattgttcca attgataaaa gaggtatgat
    15181 gtatcgcaaa ga
//
LOCUS       DAFLWQ010000070        14879 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.073, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000070 DAFLWQ010000000
VERSION     DAFLWQ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14879
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.073"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..1087
                     /locus_tag="L1V16_002137"
     CDS             <1..1087
                     /locus_tag="L1V16_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1276464.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1305..2447)
                     /locus_tag="L1V16_002138"
     CDS             complement(1305..2447)
                     /locus_tag="L1V16_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1276465.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2452..2637)
                     /locus_tag="L1V16_002139"
     CDS             complement(2452..2637)
                     /locus_tag="L1V16_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBN1276466.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2991..3236)
                     /locus_tag="L1V16_002140"
     CDS             complement(2991..3236)
                     /locus_tag="L1V16_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1276467.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3230..3631)
                     /locus_tag="L1V16_002141"
     CDS             complement(3230..3631)
                     /locus_tag="L1V16_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1276468.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3818..5626)
                     /gene="uidA"
                     /locus_tag="L1V16_002142"
     CDS             complement(3818..5626)
                     /gene="uidA"
                     /locus_tag="L1V16_002142"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HBN1276469.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(5649..7415)
                     /locus_tag="L1V16_002143"
     CDS             complement(5649..7415)
                     /locus_tag="L1V16_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HBN1276470.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7428..8222)
                     /locus_tag="L1V16_002144"
     CDS             complement(7428..8222)
                     /locus_tag="L1V16_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBN1276471.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(8232..9608)
                     /locus_tag="L1V16_002145"
     CDS             complement(8232..9608)
                     /locus_tag="L1V16_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1276472.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(9728..10375)
                     /locus_tag="L1V16_002146"
     CDS             complement(9728..10375)
                     /locus_tag="L1V16_002146"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HBN1276473.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(10459..11886)
                     /gene="uxaC"
                     /locus_tag="L1V16_002147"
     CDS             complement(10459..11886)
                     /gene="uxaC"
                     /locus_tag="L1V16_002147"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBN1276474.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(11960..13039)
                     /gene="uxuA"
                     /locus_tag="L1V16_002148"
     CDS             complement(11960..13039)
                     /gene="uxuA"
                     /locus_tag="L1V16_002148"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBN1276475.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPACEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(13042..14673)
                     /locus_tag="L1V16_002149"
     CDS             complement(13042..14673)
                     /locus_tag="L1V16_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBN1276476.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
BASE COUNT         4763 a         2945 c         1992 g         5179 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa ccggtggcaa atccatgtaa
     1141 acatggttta ttttttacac tgttttcaaa caaacccttg ctatttcttc ggttcgtcct
     1201 cgtccatttt cgataccgac agctagctta taacccaagg tatatcaaca taaaaaaata
     1261 aaaataggct atgacagcag cgtgacagca aaaaagatgg aaagttaaat atcaaacctc
     1321 gtaatttcat ttgcgagtgc ttgatttgtt tctggatata agtgtccata tttgtccaaa
     1381 gtagttttaa tagaggcatg acctagacgc ttagatattg catagatatt tttattatgt
     1441 tcaattaaaa aggcaacatg cgagtgtctt aatccatgca tatgaattgg ttttactcct
     1501 gcaatttcag ctagtttttt tattctgctt aaaatagttc ttggagatgg cggtaatcca
     1561 tcaaaagaaa aaaccaattc tatatttttc ccaattgatt gttgagtttt tttccatgtt
     1621 tttaaatctt caacggtttg tctgtctaac gaaattatcc gaatacttga tgtatttttt
     1681 gtttcagcaa attcataatc ttgtcttgta cggatgtaaa ttgacttatt tacgctacat
     1741 ctgccattta ttaagtcaaa gtctttccat tgtaacgcta agagctcctc actccttaca
     1801 cctgtaacaa aaataaaacg catcaaacgt ttataaaatt cttcataaaa atccccgtga
     1861 taaacactat tatatacttt cttaaattca tcaactgtcc aaaattctac ttgaggacgc
     1921 tgagttttta ttttacctat agtatctaca ggattttctt caataatttc aagtacaatt
     1981 gcccttttaa aaactactct caacttattg aatatctgtt taatataatt tggtgataat
     2041 ggttgctcaa tgcccttttt tacaacatgg attttcgata aaaactgttg aaattcctgt
     2101 atatgaattg gtcgaatctt tacaacctgc atttctccaa aaaaatccaa tgcacgttgt
     2161 aaaatatgat ctgttttcat atatgttttt tctacagttc ccaacttata ccaaggaaaa
     2221 aaatactctc gataaaaatc atgaaacgtt attccttgca gataaattcc ttgtgaatca
     2281 gaaaaacttt gttttaactc ttcgagtccc cttctagctt ctccttgagt tttgaagcct
     2341 cttctggtca cttgaattct ttttccaaag cgatcttgtc ctaaagttgc agaaaaaaac
     2401 caagtgcctc tttttctgtc tttataaaca ttcgcaattt tcctcatttt actattcctc
     2461 ccaagaaata tggagaactt cttctaaaat tgaaatagga attcttttta tttttgaatt
     2521 acgataaaaa aagtatcctt tctcaactaa aagttcttta cattccttga agattttatt
     2581 agcatagtac tgagaaaaac ctagattaat caaatctttt cgagtagctg ttttcattat
     2641 agcaccttcc ttactttttt tcatttattt ctatcagctg cttttgtcaa aagcacatag
     2701 gaatttcacc tctccccaag tttacggcga gccttacgga agtatcatta tcccaacttt
     2761 aaatcatcgc tttttattga ctataaaaat tattttagaa tatttatcgc tccttcttta
     2821 cagcaagaaa tcatggcgca actaaaatat gctccttaaa gtgttaacgt actgatagaa
     2881 tctatttaat tttcaatgaa caataggttt tctacctaaa agaatctact aattccttaa
     2941 ctattagaag attcttttaa acagaaaaag tggaaagggg atttttttaa ttagttaatt
     3001 ttaaatttta agatcgcttc tattaattta atttctagct gacttatcat atattcatct
     3061 acataggtaa cgaattgacc tacctcgtta aatccatttg tcaaacataa cttagccata
     3121 taagaatgat aatgtttgag tatcatcttg atcgaaattg gatctccttc tagagcagat
     3181 aagataatgg atagtggaac taataggtac tgccgctttt tagatttatc taccataggt
     3241 cataccccat tttcaattgt tcaactgcct tctttcgttg ataccagata ccacttgtgc
     3301 tcatattgag aattttaccg atttcagcat cattaaaacc tgcaaaataa taaagtagga
     3361 taatctttct tcttatctcc gataactgat caattgctgc tgataacttt tgatctgaaa
     3421 ttaatatttc cattccaaat aagaaataga catcttgttc atcaaaatga gtttgggaat
     3481 acctgccttc atttgaatct gccaatggtt cctcattatc ctttatgtta gcgtttcgtt
     3541 ttcgaataga cttagcttcg tttcgtaata cttttttaca gtaggcatca aattggtgtt
     3601 gtatagatat gtcattgtaa tgttgttgca tgataatatg ctcctttttc cccctttcca
     3661 ctaatacaac aatcagaaag cccctttttt tcgaaaaaac tagaaaaaaa acataaaaat
     3721 atttatcatt ctttaaacag aaaatctttc tataaaaaac aaaaaaaaac gattaggcta
     3781 ggctaatcgt tttttgaaca ttcttaaaaa atccaaatta ttttttataa ctgaaattgg
     3841 gtattgatga ccatcgtttc tgtagatagt aagcaatcat tttaggtttt ctatctctag
     3901 taaagattcc tttcttattt ccttgcactc ttaaaatccc ttgacttgtt gcaaaatctg
     3961 caaaattcca cacttgttca ccaacaaaat tttcacatgt atctattact tcgtgatttg
     4021 cttcgtaata agccacttga tactcttctg taaacattgt tggtactgta tcatgaaatc
     4081 cagctactgt atctgctcca tattctgtaa acattattgg cgtatcagga catctttcca
     4141 tccatccatc tagctctttt ttcaacagat attttgcatg tgccagatcc cctcccgaaa
     4201 cataccaacc ataataacga tttaaacata aaacatcgac aatatctcct accttacaaa
     4261 catctggcgt tgattttaga taagtaacga ttgttacagg tcttttctgc ggatcaagtt
     4321 ctttagttaa ttcaactaaa ggttcaaaat attctttagc accttcggaa tccgaatctg
     4381 gttcatttgc aatagaccac attacaacac ttgggtggtt cttgtcgcgt tctatcaatt
     4441 ccttgatcac cgttttatga gaattttctg ttcgtatctc tttccacgta ttatgttttt
     4501 ccacattatc atctaataaa gtggccatga aatttaaatg taaccctact gcaggtactt
     4561 catcaataac tacaatacct tctcgatctg ctaatcgcat aatttcttct gagtaaggat
     4621 aatgtgatgt tctaaaagaa ttagcaccta tccatttcat taaattaaaa tctttaatat
     4681 ttacagcctc attcaaacca cgtccattaa catacgaatc ctcatgctta ccaaatcctt
     4741 taaaataaaa aggtttatta ttaatcaaaa atttgccatt ggtaacctga acactgcgaa
     4801 taccaaattc ttctgtatag gtatcgatca ctttattatc atcaattaaa ctaattttca
     4861 tactatataa ataagcgtct agaggttccc aaaaaattgg attcttaagc tgaatcattc
     4921 ctttctttcc ttcagcttca gctacaagtt gagcctcttc gtcatatatc gctattaaga
     4981 tttttccggt ccattctgta tcgatattga attctacact tgcatccaaa tcagttattc
     5041 ttgtattaat agtaatatca cttatatagt ctttcggagt tgtatataac ttaacaggtc
     5101 tatgaatacc tgcataattg aagaaatcaa aattaactaa gttttccttt tttatatccc
     5161 cattttcctg tactgtttcc ttcataatcc ccacaggtaa agtactatcg tcaataatat
     5221 tgtttacagc aactgtaatt cgattattcc cgtcttttac aaaccgatta atttcagact
     5281 caaatggtgt aaacccacct ttgtgttgag taataaactt tccattcaaa aaaacttttg
     5341 cttcatgtgt tgcagatcca aaacgaagaa ctaatctttc ttctaataat cttttaggaa
     5401 gagtcacttc tttttcatac cacacccatc caacatgatt tctaatgttc tctgtttcaa
     5461 ataaatcatt ataagaagag ggaactgaaa tcggataact ctctttttca tttattggtt
     5521 ctaaagcaag ttcttcctgt aagtcatcat ttgtatctaa tttaaatctc cagagaccgc
     5581 ttaagtcaat tacttgcctc gtctctgtca taatgggata caacatataa accactccta
     5641 tctaaatatt aaataaatgt atcctttaaa ccacaataag catctattgg acttactccc
     5701 ttaaattcag aaagacccat tagtttgtcc accaatattt ctaaagtttc ttgttttcca
     5761 tcataagtat taatataagt ctttacttga ggtacatcag ccaaatgaaa cggacactgt
     5821 acagatacaa aaattgttgg aatttcatga atgtaaaacg gtatatccgg agttccttta
     5881 cttgctggcc agacaattcg ttgaactgtg cctggattaa cattagctat attaatgatc
     5941 aagtcatatt ttttagttaa atttttaatt ggtctcttag cagcatatat tccagctata
     6001 tttttaattt tttcttcttg cgataatcct ttcaattctt cttcaggtga aatgtatttt
     6061 tcaacttcaa atccttttgc tgacaaaatc tgtttcaata aatcaatggc ttgaggtcta
     6121 tttccagcaa ctacttcacc aaacccacct tttaccccat gtacatctac tagtaaaatc
     6181 cttttatatt tttctggtac aataggccaa atatcttgtt tatctttaac taatgtaatt
     6241 gcttggtcag ccacctcttt aaaaattgat ttattttcaa ttaaaccaat tttttccaga
     6301 gcttcttgct taggtaataa aatttgttct tttgcttttt tgtgtaatcc caatttagct
     6361 tttaacccta aaattctttt taaggcatct aataaccgat catcagtgat aattccttta
     6421 cgatagcctt ccatcatata attaaagtct tcatctggat cattaaaaaa tagaaataga
     6481 tcacatccag ctgcaataga agtgggcaat aattctgatc gtttcattgc cccagtcatt
     6541 cctaacatat gactagcatc agtaactact aatccattaa atccgagttt tcctctaagt
     6601 aagtcagtga ttaattcttt tgataaagtt gcaggaagta aatcttcatc tttcagatca
     6661 ggattaaaat gttttgaata agctggcata tggatatgac ctgccataat tgaaggtaat
     6721 ccagcttcta ttaagcctga gtatactttt ccaaaagaat tatcccattc ttccgtacct
     6781 aaactattaa tactaaaaga tagatgctga tctcgttcgt caataccgtc accagggaaa
     6841 tgtttagctg caggcaaaat tccactctcc tgaatacctt tcatataagc taaactaagt
     6901 tctaaaactt tatcagggtt ttgtccaaaa gatcgactag aaatgatagg atttctccaa
     6961 tttctattaa tatctacaat aggagcaaaa ctccagttac atccaatagc cgatgcttca
     7021 atcccagaaa ctctccctaa ttcataagca tatttcgcat catttgttgc accaattttt
     7081 acttctacac caacttcagt accatctgta caagctccgt taccacctgc ttccgtatta
     7141 gcagcaatta atagaggaat tttactttct gtttgtaaga tatagttttg atcatatacc
     7201 tcatcagcag ttcctggatt atatcgtaca gctccaatat ggtactgatt gaccatatta
     7261 ctcaagtaat ttttatcacg actagatccc atattaacaa acaattgacc tattttttct
     7321 tccaaagtca tagaatcaat cgtctcttca atccaagaaa tagcatcttc atctaaatta
     7381 tatggttttt ttcgtaaatc tacttttata gtcattttct ttctcctcta cttattagta
     7441 agatttttcc aaaaagtatc tatatatttt tgttcaatat ctacataatc tcccgataaa
     7501 catttaaata aaacatcagt tcttaagttt tcccatgatt ctttttcttt attgaccaaa
     7561 ataggataaa agaaaacttt atttttattt gcagcttcta gatcaccagg agaatcacca
     7621 atcattaata tcttatccaa atcacaacca ttttcaatta cacttcgaat aatatcttct
     7681 ttttttcctt tatcttgaca acacagttca tcaactaatg ataataattc atgtctttcc
     7741 cattcttctt gaacagcttc cttattagct gagcttacaa taattatctt cccatatttt
     7801 ttcagagctt ttatagtatc tctagcactt aaaaagggtt tatctaatcc ttttgcttga
     7861 ctaatctgtt gattgacttc ttccgaccat tttaaagctt ttaataaatc ctctgactga
     7921 gaatattcta tttccctctt caaagatgga ttagacaatt cttttgttag agatacccag
     7981 tgctttaatc gattaatcga tgttacatca tttttttcta atgttttaac taaacctaaa
     8041 aatctgttta ttccacgagt ctctgaatat aaattaatat tattccaatc ctgtaggaat
     8101 ttttctctat gatgaacatc aaaaatctct gcagcaattg gtccgaaaaa gagattgtgt
     8161 ttataagtca tcgtatccat aacacagcca tctgaatcaa tacaaaatat ccaattattc
     8221 atatttctct cctatttatg tttttgtttt aaaagctcgc aattttctaa gactttatct
     8281 ttagataatg gataaaggaa aaataaaatt aatcctacaa tcagaaaaca aattgatgga
     8341 attaatgttg aagcgttata taacttttct aaaacatctc ccgtttgtac atttgctaaa
     8401 gagtcatagc ctataataga aagagtccaa cctccgacgc ctccagctag agcttgacct
     8461 atttttctag caaaagaata taccgcatat acggtcccat cttctctttg atcagacttt
     8521 acttcttgat catcaataac atcagtaata tttgcccaaa taacagtatt aaacacaccc
     8581 aaacccatat agccaaccga actaagaatt aagaatacat acatattact agcttttatc
     8641 aaaaataaga tcaaatatac tattgctgaa aagaacattc ctactgatgc cagttctttt
     8701 tttccatatt ttttacttaa aaacaaagtt aaaggcgaaa caactattaa aaccaaaata
     8761 ggattgataa aattcattaa aactattccc tgtgcatcat tatagtaatc aggaaataca
     8821 taattattca tactcataat taataattga gcaaggagta agaaaatagc cgcaccaatt
     8881 atagaaagta atgccctatt tttaactaac ccttttaaag attttaacaa tgaaactttg
     8941 tattgagatt ggtcaattct tactcgttca gtagttagtt tataacatat taaataacaa
     9001 ataagtgcac atatcgaaaa tattcccgca acaattgtaa aagttgatcc accacgaact
     9061 atttgagcgc ctgaatcatc tcttgtataa ataaataatg gtgttaatac accaatgacc
     9121 aaacttgcta aagtagctcc aacatttcgg aatgtcgata gcattgttct ttcttctgta
     9181 atagaagtaa tagctgatgc cattgatcca taaggaatat ttatagatgt gtaaaaaata
     9241 ctcccccata atatatacgt aacatacatg tatactacct taacgctcat agaagctgaa
     9301 atcatagaag tttgatacat taaaaaactt gctaaagcga ctggaccact cattcttaaa
     9361 atccacggtt taaacttacc ctgcttagtt gctttcgatc tatcaacaat acgccccata
     9421 gttacatcag taactgcatc gataaatctt gctactaaaa ataatgttcc aacggcagct
     9481 ccgcttatcc ccaatacttt tgtataaaag atcattaaaa aagaactagc aaaaatgaaa
     9541 gtaaaatcgt ttccaaaatc tccaaacata tatcctattt tgtctcttat accaaatttt
     9601 ctttccatac aattctctcc cttctgttgt taagcgtttt cattctgatg aaagtacgta
     9661 ctatactctg aagcgtaaag agtcagtatt tattttttac atttcagagt attatttgtt
     9721 ttttctccta ataattcttt atctcataaa acttatctat atatttacta gctactcgac
     9781 ttacttcttc aaaatcacct ttttcaacag aagccaataa attcccacct acaccaactg
     9841 caacaactcc tacttcaaac caatcttcta agttctctat acttactccg ccagtaggca
     9901 ttatatttac gtgtggtaat ggagcttgat aggcttttac aatggatgga ccaaaagcag
     9961 aacctgggaa tagtttaatg atatctacgc cagcagtaag tgcctccttt atctcagtaa
    10021 ttgtcataca acctggtaaa taaggaattt gatataaatt acaaatctca gctgtttgtc
    10081 gatcaaaaga tggactaacg atatattctg ccccagccat aattgcgata cgagcagtaa
    10141 acgcatctaa aaccgtaccg gctccgatta ttacatcttt ttgatcagca tattttttag
    10201 caatttcttt gattatttct tcagcattag gaactgtaaa agttagttca atccctttaa
    10261 ttccacccgc aataattgaa tttattgctt taatggcctc atccttattt ttcccacgta
    10321 caaccgcaat gactccagcc gcttctaact tacttaaaat ttctactttt ttcatatcta
    10381 tctccttcct ttatggatac atactttgtc tagctgtact aacttacaaa gaataaattt
    10441 aagcttttat ttcaagtatt attttctact tccgatttca aaaaaattaa aataattata
    10501 cgcattacga taacaaatat tctccactat ctgactaaga tacatttcat catctggaat
    10561 tcggcctgct ttaacccact cgcttagtaa ttgacataat actcgacgaa aatactcatg
    10621 gcgaggatag cttagaaaac ttcgagaatc agtcaacata cctgtaaaat tcgacaacaa
    10681 actttgttgt gccatcgtag tcaactgttg acgcattcct tcagctgtat cattgaacca
    10741 ccaagcacat cccaattgga ttttttgaat cataccccct tggaagcttt gcattgctgt
    10801 tgctagtgga agccaatcag ttggatttaa tgaatataaa attgtttttg gtaagcaccc
    10861 actcttttca gcggtatcga acaatgctac aacattttgt gtcaaactag cttgatcccc
    10921 catcgaatca ccaccgacat ctactccaat ttgttccttt aatatacttg aattatttct
    10981 taaagcattt aaatgcattt gcatcgtcca accatatctt gtatactcag acatcaaatg
    11041 taattgaata cctgtaacaa attgtgcaat ttctgataaa tggaaatccg tttttcctgc
    11101 taaagctttt attaacagat tgtcgagtat tttttcatct gctatttcat aaaaataagt
    11161 attcaaaccg tgatctgcta atcgacagcc aatttgatga aaatgatcca ctcgttggct
    11221 caatgcttgc ttcaacccat taaagtcttt gattggtata gccgctgttt gactaagttt
    11281 taaaatatag ttcgaaaagc ctgatgattt gatactccag accttatctg gacggaaagt
    11341 aggtaatacc ttgaaagaat tatcctgttt agaaagctca gtatgatacc acaagtcatc
    11401 tgtaggatca tccgttgtac agatggcttt cacatccatc atctccaaca attctttcgg
    11461 gcgataggaa tccgtttgaa ttttttcgtt agcacgtcgc caaatttctg gtgcattctt
    11521 ctcagaaatt gtcaaatcaa tatcaaagta acgttgtaat tccaaatgag accattcaaa
    11581 aataggatta cctggcgcct tctccactgt ttttacaaaa gctaaaaatt tttcataatc
    11641 atcacctgga ccactgatca actcttcttc tataccatta gctcgcatca atcgccattt
    11701 ataatgatct ccagctcctt tatcatttaa ccatacctga gtcaaattct tgtattgctt
    11761 attttctagc aaatatgctg ggtctaaatg acaatgatag tcgataattg gttggtgttt
    11821 tgcaaattta tgaaaaagtc ttttagctat ttcattctct aataaaaagt tcttatctaa
    11881 aaacatattt aaacactcct ttccttccgt tagtttttag aagagaaaat ttttcctcta
    11941 aataaactcc cttatataat tatttactcg cccccttttc aagcgcttcc caaataccat
    12001 ttaaataaac tgcacctaga gctcggtcat ataatccata accaggtcta ccggtttctc
    12061 cccaaatcat ccgaccatga tctggacgaa tatagccatt aaatccatta tcgtacattg
    12121 tttttaatat cttatacata tctagagaac catattctga tttatgcggc gcttcgtaaa
    12181 aatcgagtcc attgtcactt aaatatttga tattacgaac atgtgcaaaa ggaatccgat
    12241 cccgttgaca aaattcagat agaatttcat agacatcatt atctggtcgt tctgcaatac
    12301 ttccagtaca taatgtaata ccattagaag gagaatccac tacattacac aaccaatcta
    12361 aatcgtcacg atttttaaca atacgaggta atccgaaaat ggaatatggt ggatcatctg
    12421 ggtgaactgc cattttaatc ccaacttctt cacatgccgg gataattgct ttgagaaaat
    12481 atgcaaagtt ctctcgtaat ttctcttcat caacttcttt ataggcttct aataattgct
    12541 taatttgtga taaccgatga ggttcccaac ccggcaattc aaaattatta gtagaatttt
    12601 ctacttctct aataatttcc tccggatcag tagggatatt ttttgaaata taggctaacg
    12661 tagaagaccc atcatctaaa cgataatcca aatccgattt tacccaatca aatactggca
    12721 taaaattata acagataacc tcaatcccaa attctgccaa attgcgaatc gtctgtttat
    12781 aattctcaat gtattgatct cgtgttggta aaccaatttt gatatcatca tgaacattaa
    12841 cactctcaat aactttcaag gtaagtccat tggcttcgac ttcatctttt aaagatttaa
    12901 ttcgttctct cggccaaacc tctccggctg gtatatccat taatgttcca acaattcctt
    12961 tcattgctgg gatctgacga atttcttgta gtgagatttt ttcttcattt gccccatacc
    13021 atctaaaagt catttccata gttactttcc tccaacttct gttatatatt tattgattgt
    13081 tttacgaact gcttgaggac ctactagcat ttcgcaaaag attttttcag ttttctttcc
    13141 taccccaact tgatataaat ctaaaccaaa gatttcttta ttttctaaaa tttcctgtac
    13201 cgcacaatga atctttgaag gatcttgttc acctaatttc aatactgata atttatcctg
    13261 caactctacc aataacggat caggacttgg cacaaaattt tccccttgat catcgactgc
    13321 cagtaaataa cgtaaccaag cagcaatagc gataggaata aatgttagat tttctgcatt
    13381 tccgtctttt tcgacatact ttttaattgt ttcaccatag cgaatcgcta ctttttgaga
    13441 agtatctgtt gcaattcgtt gtggtgtatc tggaatatag ggattaggca aacgtttatt
    13501 aattacttca tcaataaatt gttttggatc aataatgcct ggattttcaa ctactggtaa
    13561 accttctaaa taacctattc ctttgattaa accaaccaaa tcatcatcct gcatctctgc
    13621 tgaaattgat tgatatccta gcagacaacc tgttactgcc aaagcagtat gaagtggatt
    13681 caagcttgtc gtaaccttca tgatgtctgc tttatcaacc gtctctctat ctgtcataat
    13741 cacaccagcc ttttccaatt taggccggcc atttggaaaa ctatcttcaa taactaaata
    13801 atgaactacc tcagtattag tgaaagcagc aatattggta tgtttttttg tgtgaatgat
    13861 atctaaatcc tcgagcccca tcatcaatag atcttccttt acattctctg aaggatttgg
    13921 cgtaattcga tcaatcatac tccaaggaaa agtcactttt tctttatcct ttaaataagc
    13981 aataaatttt tcagaaacat atccttcttt ttgccaagct tctgcaatcg taaaaatact
    14041 atcttgaaaa cgttgaccat tctgtgagaa attatcagta gaaaccatcg caatcggcaa
    14101 ctctccagca ttaaatctgc tatataacaa ggatgttaca atactcatcg tatgttgagg
    14161 attgctaggt ccagatttga tatcagcttt gactaccgaa aagaattgcc ctttagaatc
    14221 ttttaaactg taaccttttt cagtaatagt aaacgttgta aactgtaatt taggatcttc
    14281 aaaatattta accactcttt gatagtccgc tatattcttc ggattgcaat ataaactatc
    14341 agccgttact gccaaaagtc tttttttgag ttcaccatct ccactcataa caatttccaa
    14401 aatgtcattg ttatagtcat gataagcttt ttccactact tcttcatcaa atgtttcaca
    14461 cacaactact cctgtttcta attcattttg atctgctaag cattgagcaa tttctgcatg
    14521 aaatcctcga taaagatttc ctccaccaaa atgaagccat actggatgtt gctggccttc
    14581 ttgcttaact tctttgacat caaaacacgg cagtagaatc tgcatttcat tgaattcttc
    14641 gatagaattt tgccaatttt taatcgaaac cataattaac ctcctcaaac tgatatgtta
    14701 gttttgatac attttatatt ttaaaaccca ttgtaaccgt tgtcaatata aaaagggaat
    14761 aaacttgctt ttttctacca tatcagaatg attgtatttt ttattcagaa aaataaaata
    14821 ctccttcttt ttggactgat tttatcgaaa cttatttttt ctttttttca tgtattctt
//
LOCUS       DAFLWQ010000071        14645 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.074, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000071 DAFLWQ010000000
VERSION     DAFLWQ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14645
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.074"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..270)
                     /locus_tag="L1V16_002150"
     CDS             complement(<1..270)
                     /locus_tag="L1V16_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1276477.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCG"
     gene            543..3014
                     /locus_tag="L1V16_002151"
     CDS             543..3014
                     /locus_tag="L1V16_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBN1276478.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(3117..4853)
                     /locus_tag="L1V16_002152"
     CDS             complement(3117..4853)
                     /locus_tag="L1V16_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBN1276479.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4850..5554)
                     /locus_tag="L1V16_002153"
     CDS             complement(4850..5554)
                     /locus_tag="L1V16_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1276480.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5685..6188
                     /locus_tag="L1V16_002154"
     CDS             5685..6188
                     /locus_tag="L1V16_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBN1276481.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            6148..6486
                     /locus_tag="L1V16_002155"
     CDS             6148..6486
                     /locus_tag="L1V16_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBN1276482.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6507..7925
                     /gene="ffh"
                     /locus_tag="L1V16_002156"
     CDS             6507..7925
                     /gene="ffh"
                     /locus_tag="L1V16_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBN1276483.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            8037..8615
                     /locus_tag="L1V16_002157"
     CDS             8037..8615
                     /locus_tag="L1V16_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBN1276484.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8619..9140
                     /locus_tag="L1V16_002158"
     CDS             8619..9140
                     /locus_tag="L1V16_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBN1276485.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(9219..9773)
                     /locus_tag="L1V16_002159"
     CDS             complement(9219..9773)
                     /locus_tag="L1V16_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBN1276486.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            10026..10301
                     /gene="rpsP"
                     /locus_tag="L1V16_002160"
     CDS             10026..10301
                     /gene="rpsP"
                     /locus_tag="L1V16_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBN1276487.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            10313..10564
                     /locus_tag="L1V16_002161"
     CDS             10313..10564
                     /locus_tag="L1V16_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBN1276488.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10689..11480
                     /locus_tag="L1V16_002162"
     CDS             10689..11480
                     /locus_tag="L1V16_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276489.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11650..12171
                     /gene="rimM"
                     /locus_tag="L1V16_002163"
     CDS             11650..12171
                     /gene="rimM"
                     /locus_tag="L1V16_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBN1276490.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            12161..12922
                     /gene="trmD"
                     /locus_tag="L1V16_002164"
     CDS             12161..12922
                     /gene="trmD"
                     /locus_tag="L1V16_002164"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBN1276491.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            13058..13405
                     /gene="rplS"
                     /locus_tag="L1V16_002165"
     CDS             13058..13405
                     /gene="rplS"
                     /locus_tag="L1V16_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBN1276492.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            13663..13956
                     /locus_tag="L1V16_002166"
     CDS             13663..13956
                     /locus_tag="L1V16_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBN1276493.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
BASE COUNT         4892 a         2637 c         2968 g         4148 t
ORIGIN      
        1 tccacaatca tggcagagaa aacgggtacg ttttaattct aaaatagtta acttttcttt
       61 gactttcaac atctgagtgc gtgtcgtata ggaaccgttg cggataatac gaaccgatcg
      121 acagtgttca caataggaag aagagtcatc caattttcct ttaataaact gcgcttgaac
      181 gcctttatat tctttttcaa tcagccattc ttcatcaaaa aataaatgtt tatctgttaa
      241 tccgagtaat tttctagtat gattatccat tgagagactc ctttggtagg atgacgtttt
      301 ggtcgactaa attttaccaa aagtgagtct ctttttgagt tgaaacgaag aaaaagtgtt
      361 agtagaaaat cgccttcgat tttccaccaa cacaaaatat tatagaaccc tttttttttg
      421 ctatatgaca ggaatgaaag gtgtttgcaa gcttaatgtg aggaacactt tccatatctg
      481 ttctatactg gataggagaa gtttggaaat atccagaaaa cgaaatcaat cgaggtagcc
      541 acatgaagaa taaatggata aatcgaagta aaaaaaagaa agtaacacaa agatcatcag
      601 ataaagtcat ccgtcttttt ccatcgtata aagaaggatt aacggcagat caagtcaagg
      661 aacgaataga aaaaggtgca gcaaataatt cagtcgatcc cacattcaaa acaaatcagc
      721 aaatcgtatt ggaaaacata tttacgtatt tcaatttgat ctttcttatc ttagccattt
      781 tgctttgttt agtagaatcc tataagaact tgactttttt accagttatc atagccaata
      841 caggaatcgc catttttcag gaaattcgat ccaaaaagat cttggacgaa ctaaatgttt
      901 taaatacagc aaaagtcaat gtcatacgag acgggataga acaaacaata gatatagaag
      961 accttgtaat agatgacatt gttattttag agactggata tcaaattcca gcagatgcag
     1021 aggtcgtgga agggaaactg caagttaatg aggctttatt gacaggcgaa gcagatgaaa
     1081 taaccaaaga aataggtgat ccattaatgt ccggcagttt cattgtttcc ggaaaagctt
     1141 acgcccgatt agacaaagtt ggagcagatt cgtatatttc ccagctgaca gtcaaagcca
     1201 agacaatggg agaaggagaa cagtcggaga tgattgcttc tcttaatcaa ttgatcaaat
     1261 ggattgggat catcattatt cctatcggta tcctgctttt ttctcaaagt tactttttta
     1321 atggaaacac gatcaaagaa agtgtcgttg caatggaagc agcattgatc ggtatgatac
     1381 ctgaaggact gtacttgctg acgacgattg cattagcatt aagtgcgact aaactagcaa
     1441 agcaaagagt tcttttacac aatatgaaaa gcattgagac attggcaagg gtaaatgtcc
     1501 tttgtgtaga taaaacagga acgatcacag aaaataaaat gtctgttcaa aaaatgatcg
     1561 tctctaaaaa acaagaaata atcagtcagt cagatcaatt ggaagcatgc attgctgact
     1621 atgcaaaagc gatggcagga gacaatgcaa caatggaagc tgttaaagca tattttacaa
     1681 aaaccactga tcaatcctat caccatgtta ttcctttttc ttctgtccaa aaattcagca
     1741 gtgtagcgtt ggcagacaag gtgtatgttt taggagcgcc cgaaatggtt ttgcgcgatc
     1801 aattgccgga atatgcggaa gagtttgttt ctttcgctga aaaaggctat cgcgtgttgg
     1861 tctttggtgt gtacgatggg attcttgaag aaccagtatt gacagaagca gtcacaccat
     1921 taggctatat tctgattgct aatcctatca gaaaagaagc aagagccaca tttgattact
     1981 tcaaaaaaca gcaagtagcc atcaaagtga tttctggaga taatccgctc accgtatcca
     2041 atgtagctgt ccaagcaggg atttcacatg ctgatcagta cgttgatgca tctaaattat
     2101 cagaagaaga atatgaagca gctgtcgaaa aatatacagt ttttggacgc gtcaagccag
     2161 aacaaaagaa aatcttcgtt caattgataa agcgtaacaa tacagtagct atgacaggtg
     2221 atggcgtgaa tgatattcta gccatgaaag aagcagactg cagtatagcg atggcttccg
     2281 gaaatgaagc cgccatgcag gcctcacaag tggtcttact tgattctgac ttttcacgca
     2341 tgccagaagt tgttgcagaa ggacggcgcg ttgtgaacaa tattgagcga tcagccagct
     2401 tgtttttagt gaagaatatt ttctcctttt tgctctcact gttttcagtg atctttgctc
     2461 tgacctatcc tttagaacca tcacaaatca cattgattag tttgtttact atcggacttc
     2521 catctttctt gcttgctcta gaagaaaaca aaaagcgaat cagagggaaa ttcatcatga
     2581 atgtgatgga aaaagctgtg ccaggtggac taacagatat gatcgtagtc ggtgcgttgg
     2641 tgatctgcgg ggtgactttg aatctaaata aaacagatgt ttctacagca tctaccatgc
     2701 ttttgattgc agtagggttc ctcgttctct ataaaatctg ttcaccgctg aataaattca
     2761 gaagtcagat cattcttttc tgtgctagcg gtaacttttt ttcggtcatc tttttgcata
     2821 agctgttttc aatcaccggt atctcagctg tatcactttt gctgttgagc attctatttt
     2881 tctcggcaga ttcgattttt aggcatttga ccacattggt agaatatttg tttgaacgta
     2941 aaaatgaaaa agagcaaaag ccgtttagtc gcgtagctaa aaaatttcta tcgatattta
     3001 aacgagaaaa ttgacgaaaa gtatctcaaa aaagagtaaa aaagaacaac cactcgtgta
     3061 tctttcgaag caggatgagt catccaactt taaaacgcac gagcagttgc tcttttttac
     3121 attttcggaa tggtaacggt gaaagtcgaa cctgttccaa gatgactgtc tacagtaatc
     3181 gtaccattaa ggagttgcac gtagtctttt acaatcgcta accctaatcc ggtcccgcct
     3241 gaatgtcggc ttcgcgcctt gtctacgcgg taaaaacgct caaagatccg ttcctgatcc
     3301 tcaatgtcga tacctatacc aaagtcttgg acagaaaacg atagatcatc tgttgcctga
     3361 tagcggataa taatctcgct gtcgcttttt gaatattgga cagcattttc aatcagattt
     3421 ttgataattg gataaaggat atctgtttta gtagtaaatg gttcgttctt tccaatcaat
     3481 cgaatcgtca accgtttctt ttcgatgatt ggctgataat tttgaacgat ttgctggaaa
     3541 taaggttctg tataaattgt ctggatctcg taagaattct cgccatcttt tgacagctgg
     3601 atgatttccc gaatcagttt atctaaccgg atcgcatctt tttgcatgat ctcaagaaaa
     3661 gaagtcagag tttgcgggtc atcttttgca ccatccagta aagtctcggt aaaaccaatc
     3721 agtgaagtca caggagtttt taattcgtga gagacgttgc caacgaaatc cttttgtagc
     3781 ttttctaaac gtcgcacttt cgttaagtca tacgccaccc ctagaatctg tccggtacct
     3841 tctgaattag taaagtagcg caaactcaag tctaatgtct gccgaccttc tgtaagggtg
     3901 atctcctgat ggatcagcgg atgctcagga gtcacttgat gaatcagctg aatgagtttt
     3961 ggctcttgaa tgacttctgt gtaccgctgt tcaggttgat agcttaccac gtttaaatgt
     4021 agctgcatct ttggattaag cagtagtaaa cgagaatcag catcatcaat caggaatacg
     4081 ccaatcatca gttcgttcag taacgtatat aattgctctt ctgtggtagt acacgcccga
     4141 tacatcttac tcatttgttc gctcaacgca ttaatcgtct gatacaattc ttcccattga
     4201 tcgggtgttt gcatgattac ttccgcctga ttaggatttt gcaccatttt ttttagtacg
     4261 ggcagcacgg ttttcaatgg ctggtttttt tgatagatca gataatagat cattcctgca
     4321 agaacaagga agaaagacag aaagaagaaa aagacccaac ggcgaaaact ctcagttctc
     4381 ggtaaaaaaa cgcttgtcgg ttctgcgata cgtaaaatgg cttctaactg gccacttttt
     4441 ttgactggta atgcgacata taaaagatcc tcattcaaag tagtactttt gcgcaaagcg
     4501 ctacctaggt tcccaccatt caatacggct ttgatttcgg gacgggagtt tcgctgttca
     4561 ttcaatgttt cattgtttgt gtcaaataag atctttccag tagcatccat taaagtaatc
     4621 cgttcgttcg actgatggac gaattcttcc aaagcagttt tgttttgcgc tgcttggagg
     4681 ttttcgacat ctaattgccg gatcagcagt tgtgcttttt ttgtcaggta gctttcttgc
     4741 tgttccacga tctgctgttg aaaataatgg gaaatcaatt gccagccacc aaaaaacaaa
     4801 ctaactaaaa gaataagaaa gaagagacgt tcataaattt ttttccattt catcgtttgg
     4861 gttcctgaaa cttatagcca aatcctctaa tagtcaccaa gtactttggg tgttttggat
     4921 ctcgctcgat tttttctcgc aaatgactaa cgtgtacatc tacgattcgg ctttgtcctg
     4981 cgaagtcaaa attccaaatg cggtctagca atgtgtctcg gtcgatcaca cggtcttttc
     5041 gtttcatgaa ataaacaagt aattcaaatt ctttcggtgt tagttcaatc agatggtcgt
     5101 ctacggtcac ttgataattg gtcaaatcag cagtgatttg tccaatcgat agatattcag
     5161 gctcagcttc atcttttgat tgcttacgag gttcaattcg tctgaatatt gctttcatac
     5221 gggctaatac ttcgcgagga ctaaatggtt tggtcaaata gtcgtcagca cctatttcta
     5281 ggccaatgat ccgatccact tggtcatctt tagccgtcag catcaaaatc ggtgtttcat
     5341 ttttttcttg acgcagccgc tgagtgatct ccatgccatc catcgttgga agcatcacat
     5401 ctaaaatgat gaaatcaaat gattgttcta atgctaattc taatccttcg cctccatctg
     5461 tggcactggt taccttgtag ccttcttttt ccaaattgaa cgtcaagagc gttacaatag
     5521 aaggttcatc atcaacaact agtatttttt tcattcaaat ctcctttaaa taggtttcat
     5581 tctgtttata ttttagcata gaatcagtac aaagggctat tttacaaaag aaataaatgg
     5641 tataatagga aggcactttg ctgaatagaa aggaagagca gtcaatgatt ggaatcagtg
     5701 catgtttagg cggtctggcc tgtcgctatg atggacagaa aaaagaagta ccagaattga
     5761 tggaactagt tgaaactgga gaagctgtca tggtctgtcc agaagtgatc ggcggattac
     5821 caattcctag agatcccgct gaaatcattg gtggaaatgg attcgatgtg tggaaagatc
     5881 aagcaaaagt atggacgaca agcggcgaag atgtaacgga agcgtacaaa aatggcgcga
     5941 tcaaagccta tcaaaaattg caggaaaaac acattgatct agtcatcatg aaggaaaaaa
     6001 gcccttcatg cggaacccat tcgatttatg acggaagttt ttccggaata aaaaaaaatg
     6061 gtgccggagt ggctactgct tattttattc agcaaaaaat gactgtgctc tctgatgaag
     6121 aatggctgaa aactagaggt gagcagaatg gaaatcgaaa agaccaatcg aatgaacgcg
     6181 ctctttgaat tttattcgac cttattgaca gaaaaacaaa tgaactacat ggaattatat
     6241 tatgcagatg atttttcatt aggtgagatc gcggaagaat acgaagtaag ccgacaagca
     6301 gtatatgaca atatcaagcg gacaagcaag atcttggagg attatgaaaa aaaactccat
     6361 cttttttcta attatattgt tcgagaacag gtattggaaa atatgactgc atatattaca
     6421 gataagtacc cggaagataa aaaactactt gaatatgtac agcaaattca agcaatcgaa
     6481 gaataaataa aaggaatgaa gaaaatatgg catttgaaag cttaactgaa cgtctccagc
     6541 aggcgatggg aaaaataaga aaaaaaggaa aagtatcaga agctgacgta aaagaaatga
     6601 tgcgggaaat ccgccttgcc ttactagaag ccgatgttaa cttgcaagta gtcaaagatt
     6661 ttactaagcg cgtacgcgaa cgtgcggtag gggcagaagt gctggaaagt ttatcacctg
     6721 cacaacaaat cgtaaaaatc gttgatgaag aattgacgat cacacttggt tctgaaacag
     6781 cagagttaaa taaatcacca aaaataccaa ctgttatcat gatggctggt cttcaagggg
     6841 caggtaaaac gacctttact ggtaaattag ccaattattt aaagaaaaat gaaaatgctc
     6901 gtccgctcct aatcgcaggg gacgtatatc gaccagctgc gatcgaccaa ttgaaagtat
     6961 taggtcaaca gctagacgtt cctgtatttg atatgggaac tgaagtcagc ccggtagaga
     7021 tcgtccgtca agggatggag ttagcaaaag aaaagaaaaa cgactatgta ttgatcgata
     7081 cggcaggacg tctgcatatc gatgaaacat tgatggatga gttgaaacaa atcaaagaat
     7141 tgacgcaacc aaatgagatt ttgcttgttg tcgatgccat gactggtcaa gatgccgtca
     7201 acgtagctga tagcttcaac cagcaattag gtattacagg ggtcgtcatc actaaacttg
     7261 atggggatac tcgaggcggg gcagcactat cgatccgctc agtgacaggc gcaccaatca
     7321 aattcatcgg ttctggtgaa aaattgactg acttagaagt attccaccca gatcgtatgg
     7381 ctagccgtat ccttggtatg ggggatatgc tgacattgat tgaaaaagcg cagcaagact
     7441 acgacgagaa aaaagcggaa gaacttgcac agaaaatgcg ggaaaattca ttcgatttca
     7501 atgactttat tgaacagctt gatcaagtga tgggtatggg cccactggaa gatctaatca
     7561 aaatgatccc aggaatgaat caagtccctg gaatcgaaaa cgtcaaggta gatccaaaag
     7621 atgttgaacg caaaaaagcg atggtttatt ctatgacgcc agcagaaaga gcaaatcctg
     7681 atctgttgaa cccaagccgt cgtcgccgaa ttgctgccgg ttctggaaac agtgttgttg
     7741 aagtgaatcg aatgatcaaa caattcaagg aatcaagaaa aatgatgcag caaatgtcca
     7801 aaggggatat gaacatccca ggtatggacc aaatgtttgg ttcaggcgtc aaaggaaaac
     7861 taggcaaaat ggcgatgaat cgaatgatca agaaaaataa gaagaaaaag aaaaaacgga
     7921 aataagatga aaaaaacagc ttcggtacag actgaaaatg tctactgccg gagcttttct
     7981 atcagcaatt tttattcttt actaatacaa ttactctaaa cgaagaggtg gcacagatga
     8041 gatgtccgtg gagtgaacaa acagaaagta tgcggcaata tcatgatact gtctggggtg
     8101 ttcctgaata tgatgaccaa aagctgttcc gaaaattgat gcttgatatt aatcaagccg
     8161 gattgagctg gcagacgatt ttaaataaaa gtgaagcatt cgatgaagca tatgatcgat
     8221 tcgatatcaa aaaagtcgca aattatggag aaacaaaaat cagtgaacta atggaaaaca
     8281 aaggaattat tcgtaaccga agaaaaatcg aagcagccgt ccaaaacgcc aaagcagtct
     8341 tgaaaattca agaagaaatc ggcagttttt cagagtatct ttggtcgttt tctaatggaa
     8401 aaatcgttga ttcttcttat cattcacaag aagaagtccc aacaacaagt cctctttcag
     8461 atgaattagc aaaagatcta aagaaaagag gatttaaatt tatcggaagc acaacaatct
     8521 atgctttttt agaagctgtc gggatcatca atgatcacct tgacagttgt ttccgcaaag
     8581 aagaggtcgt acgtatcggc agaaagggcg aataaagcat gcgaaaaatc atattttatg
     8641 gtgctataag tttagatggc tatttggcaa cgaaaacgga tgatcttcaa tggctttttg
     8701 acactccaac aggtaagcaa actacttatg aagcttttta tgaaacaatc gatacgacca
     8761 tcatgggcag aaaaacttat caggaagcaa aaaaatattt ggagaccgaa gcaatttatc
     8821 cagagaaaaa gaatttcgtt ttttccaccc acgcacaatt acaattgcca gatgctgagg
     8881 tcgtaaacga agatcctgtt gcttttctaa aaaatctaca aatgacagaa ggaaaagata
     8941 tctgggttgt gggtggcggt cgattgatca aaccgctatt ggaacatcaa atgattgatg
     9001 aatggtatat ccagattacc cctgtattat taggggacgg gattccttta ttccaaaaag
     9061 gaacatatga agcgcgtttt gaaatgctag acacgacacg attcggtgaa tttatcgaat
     9121 tgcattatgt acgaaagtag aagtaaataa aataaaaaag gcaactatat gcagaaatgt
     9181 cctgtacata gttgcctttt ttattaccgt tatgcttttt actctgttaa tttgttagaa
     9241 aaatctagat acgcatctaa aatcgtttgg aagaaactta atgttccttc aacgatatta
     9301 ccattttcat caattagatt cgcaacgttt ccgatatatg cttccggttg ctgcaaggtt
     9361 ggcacattca aaaagacaag tgattggcgt agatggtggt ttgcgccaaa gccgccgatc
     9421 ccacctggtg atgcagtaac gactaaacct ggtttatgat cccaaacact gtgtccataa
     9481 ggtcttgagc ctacatctaa agcatttttc aatactgctg gcacagaacg gttgtattca
     9541 ggagtaacga aaacgacacc gtctagtccc ctcacttcct cacgaaaacg agtccattca
     9601 gcaggagcct gttctggagt ttcgagatcc tcattgtaaa atggcagatc atcgattttt
     9661 acaaatacac tttcgtaccc ttcaggaagc aatttcgcaa aagcttctgc tacttttttg
     9721 ttgtaagaat cttttcttaa actaccaata aaaaatccaa ttttttttgt catacgattt
     9781 ttcctccttc aaactatcta taataatctt acaaaagata agtaactgga gcaaataaaa
     9841 acacttactg acaaaagcta catagaagat agattactta tttttaacaa aaaagaagtc
     9901 taaaatcttc tattttctaa aaaaaatcga atttaatcaa gctgtaaaga aaaaaagctt
     9961 tacagggtaa aaaaaaactg ttacactaca tcttgtgaat aaaacaatgg aggtggaaat
    10021 aaataatggc agttaaaatc cgtttaaaac gtatgggttc taaaaagagt ccgttttacc
    10081 gtatcgtcgt agctgattca cgttctcctc gtgatggacg tttcatcgaa actgtaggta
    10141 cttacaatcc tttgaaagac cctgcagaag tagttttaaa agaagactta gttcttgact
    10201 ggttatcaaa aggtgcacaa ccttctgaca ctgtacgtaa catcctttca aaagaaggcg
    10261 ttatgcaaaa acaccacgaa gctaaattct caaagaaata aggtgaccgg atatgaaaga
    10321 tttaagcgac ttagtcttaa caatcgttcg tccgctagtc acttatcctg atcaagtcaa
    10381 gttagacgtc gtagagtcga aagactttta cgagtacaat ctaacagtgg ctcctgaaga
    10441 tattggccgt atcattggaa aacaagggcg tgttgctaaa gcaatccgca caatcgttta
    10501 cggtgttcgg atcaatgcac cgaaaaaagt gcgtttgaat atcatcgatg ataaggaaaa
    10561 gtaaataaac ggtctgtact cgaattttcg agtgcagctt ttttgttttt tttattaatt
    10621 gaagaaatga ttatttggca aaacaagcaa gaaagcgtat ccttatagga ggagggagtg
    10681 aacagccaat gagaaagaaa atgttattta ttccatttgc tctattgtta agcgcttgta
    10741 gttcggttac tcaagaatca gacaatacac atctatcaag cagtatatct gaaactgtta
    10801 ccagtccaga aaaaagtagt accaaaacgg cttccaccac tgaacaaaca atggctacct
    10861 caaataatga gaaaaagact gctttagacc agttgaaaga acaacagcca aatgttccca
    10921 tgcctctaga tgtaccagtc tcttcaggct atctcaatat cgcagcgaca catacaaagc
    10981 aaggttattc tattttatat tacagaacag atcgtcccct cgggttgaat gctgacgaat
    11041 tgaatcaaga aacgcctatt gcaacctatc tatatcaata tgggtttgct tctagtcaag
    11101 aaacaatcca agttttgcag ccatttgaga tcgacacaaa tggtcagcaa gtggacttag
    11161 gttctcgaat cacagggtat cagcaaggtg cagcaggttc aagttttctt gaatggcaag
    11221 aaggaaactg gcgtattcga atccgtggga ataatataga aggccaagat cccttactat
    11281 tagctaaaga aatcgtagct tatttggaag aaaacagtct accagcacct gaacaatttg
    11341 gtaaaattac tgttgatatg ggtgatacga cgaatcgagc cgtagaagta agctggcaag
    11401 aaccgaaaaa tgcctatacg atcactcatc aagatcctat gtctgcgttg aagatggcag
    11461 tttctatgaa gaggttgtga aatcagcgcg ctgatctgag cccatcattt aactccaagt
    11521 cacaggaagt aatcaaaaat agcacgccgc atttttgcat aattttggct taatacctta
    11581 aaagaaaact agaattgcct cttcacacat gctaaaataa aacagacaaa aaagaaatgg
    11641 ggatataagt tgactgaata cttgaatgta ggaaaaatcg taaacacaca aggtatcaaa
    11701 ggcgaagtcc gtgttatctc aacaacggat ttcccagaag aacgttacaa aaaaggaacg
    11761 gtgctaacac tattccaaga cggaaaagca cctgtggaat taacagtcaa aagtcatcgc
    11821 aaacataaaa attttgactt attgagtttt gaaggacatc cttctatcaa tgatgtggaa
    11881 aaatatcggg atggcatatt aaaagtgtca aaagacaact ctgtagatct agctgaaaat
    11941 gaattctatt accatgagat catcggtctg catgtattag aagatggaac tgagttaggt
    12001 aaagtaaaag aaatcttgtc accaggtgcc aatgatgttt gggtcgttca acgtccgaaa
    12061 aaagctgata tattgcttcc atatatcgct tctgtcgtca aagaagtcga tttagaagct
    12121 ggagtggtcc gtgtagaaat tccagaagga ctgattgacg atgaagattg atgtattgac
    12181 tttatttcca agaatgtttg aaggtcctat gggggaatcc atcatcggta aggctgtaga
    12241 taaaggatta ttagatatca atatctctaa cttccgcgat tattcagata acaaacatca
    12301 gacagtagat gattatccat acggcggtgg agcaggtatg ctgctcaaag tccagcccat
    12361 ctatgataac atccaagcca ttgaaaaagc tgcaccggat gtcaaaaaaa gagtaattct
    12421 tcttgaccca gctggtaaac gattcgatca gaaaatggca gaagaatttt cacaagaaga
    12481 acacttagta ttcatttgtg gtcattatga gggatatgat gaacgtatcc gcacattagt
    12541 gacagatgaa gtttccttag gagattatgt ccttactggg ggagaattag gtgcgatggt
    12601 catgatcgat gcaacagttc ggcttttgcc agatgtgtta gggaatcaga cttcagctca
    12661 aacggattct tattcaaccg gtttattgga acatccccaa tatactcgcc cggcagaata
    12721 taaagggatg aaagtaccag aagtattgac aaatggaaat cataaattga ttgaagaatg
    12781 gcaattaaaa gaatcactaa gaaggaccta tcaacgtcgg cctgatcttt tggaaacact
    12841 tgaatggaca cctcaaatga cgaaattttt agaagaaatc aagaaagaag aacaagaaaa
    12901 aacagcagat gaagccaagt gactttttct aaaatcttct ttacagtagg ttgataatat
    12961 gttagtattt tatggtgagt gcaaaagcac ttaactatta cgatattccg ctgtgagaaa
    13021 agctcataag aatatttgga ataaggagaa gaaaaccatg aatccattaa tcgaagaatt
    13081 aacaaaagaa caattacgtt ctgacatccc agcgttccgc cctggtgaca ctgtgcgtgt
    13141 tcacgcaaaa gttgttgaag gtactcgtga acgtatccag ttatttgaag gtgttgttat
    13201 caaacgccgc ggtgctggaa tcagcgaaac ttatacagta cgtaaagttt ctaacggagt
    13261 gggcgttgaa cgtacattcc cattgcatac accacgtgtt gcaaaaatcg aagtagttcg
    13321 ctacggtaaa gtacgtcgtg caaaattgta ctacctacgt gcattacacg gaaaagctgc
    13381 tcgtatcaaa gaaatccgtc gttaatcatt gttatcagac tgagaaagaa cccttggtat
    13441 tcaagggttc ttttttctta gcatgtaatt tgaacaccct gatccagttt tttctttaat
    13501 tattggtagg ggagaataat ggattagaat aaatctacct ataagtagta gtaaaaaaaa
    13561 gagcactatg ataatatctt tcttaagagt aaccgcttta ataaaaaatc cagaatattc
    13621 taacataaat ggagtattct tagaatcaaa aggagaaaga agatggttta tacttatacg
    13681 gagcaagaaa agatgaaagt tttagacaca ttcatgaatg atggaaaagt aaaacaagta
    13741 ccaagttcaa caaaaaagaa atacatccta ttgaaagaag tcttgaaacg ctttgaccat
    13801 ggagtgactt atacagaaac agaggttaat tcgatactgc tgaacgtatt ttctagtggc
    13861 gattatgtcg aacaaagacg ttatctaatc acatttggct ttttcaaaag aagttcagac
    13921 ggtcgggcat atcagatgat gggaattgaa aattagaagt tttaatttat actcattgaa
    13981 aaaagttcaa gtatgcgata ttggttctac accgcatact tgaacttttt ttgtcatctg
    14041 tatctataat acaaagccaa gaacgttatt caaaatatgg atagctatga taaaagctaa
    14101 tgagcgattc gcagttaaat aagcaatcgt cagtaaaatc gttccaggag cgtacatgaa
    14161 aaaatcaatt ggatgcgtta catgaataaa gataattctc ttttatttgt acgaataaat
    14221 accaaaacgt acctcctaaa attagatttt ggacagatgc cctttaaaaa gataacaaga
    14281 tttcgttctt gaaacaatat atatgctttt attccaatga ggttgtgaaa acagtatttt
    14341 gtcctgagcg ttagaaaatt gaaaatgggg aatagcaact cgtactttac cattttttaa
    14401 gtgaatacaa gatcagctaa ttgaacaccg tttattcgtg atgagggaca caacactgca
    14461 gtcgacacat ttctctttta tgttcaaaga taacaaatat ttaaaacaaa gaaaaatagt
    14521 agataatccc gtcctaactc ttttattctt ccctcatagc ttccaaattt aagcaatact
    14581 tcaattaatc aagttttatc tttttttttc aataatcgta aaaaaagagt attttttatt
    14641 taaaa
//
LOCUS       DAFLWQ010000072        13917 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.075, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000072 DAFLWQ010000000
VERSION     DAFLWQ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13917
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.075"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            131..505
                     /locus_tag="L1V16_002167"
     CDS             131..505
                     /locus_tag="L1V16_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBN1276494.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="L1V16_002168"
     CDS             complement(619..1248)
                     /locus_tag="L1V16_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBN1276495.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="L1V16_002169"
     tRNA            complement(1382..1454)
                     /locus_tag="L1V16_002169"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="L1V16_002170"
     tRNA            1668..1741
                     /locus_tag="L1V16_002170"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="L1V16_002171"
     CDS             complement(1879..2043)
                     /locus_tag="L1V16_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276496.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="L1V16_002172"
     CDS             2338..3666
                     /locus_tag="L1V16_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HBN1276497.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="L1V16_002173"
     CDS             3868..4701
                     /locus_tag="L1V16_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBN1276498.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="L1V16_002174"
     CDS             4717..5454
                     /locus_tag="L1V16_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HBN1276499.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="L1V16_002175"
     CDS             complement(5609..6577)
                     /locus_tag="L1V16_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBN1276500.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="L1V16_002176"
     CDS             6809..7642
                     /locus_tag="L1V16_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBN1276501.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="L1V16_002177"
     CDS             7676..8515
                     /locus_tag="L1V16_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1276502.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="L1V16_002178"
     CDS             8541..9101
                     /locus_tag="L1V16_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBN1276503.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSLNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="L1V16_002179"
     CDS             9300..11021
                     /locus_tag="L1V16_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HBN1276504.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="L1V16_002180"
     CDS             11186..12328
                     /locus_tag="L1V16_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBN1276505.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="L1V16_002181"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="L1V16_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBN1276506.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         4751 a         2297 c         2833 g         4036 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcactta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttg
//
LOCUS       DAFLWQ010000073        13807 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.076, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000073 DAFLWQ010000000
VERSION     DAFLWQ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.076"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(161..2158)
                     /gene="tkt"
                     /locus_tag="L1V16_002182"
     CDS             complement(161..2158)
                     /gene="tkt"
                     /locus_tag="L1V16_002182"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBN1276507.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2260..2511)
                     /locus_tag="L1V16_002183"
     CDS             complement(2260..2511)
                     /locus_tag="L1V16_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HBN1276508.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2658..3281
                     /gene="lexA"
                     /locus_tag="L1V16_002184"
     CDS             2658..3281
                     /gene="lexA"
                     /locus_tag="L1V16_002184"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBN1276509.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3461..3679
                     /locus_tag="L1V16_002185"
     CDS             3461..3679
                     /locus_tag="L1V16_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276510.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3968..4480)
                     /locus_tag="L1V16_002186"
     CDS             complement(3968..4480)
                     /locus_tag="L1V16_002186"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBN1276511.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="L1V16_002187"
     CDS             complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="L1V16_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBN1276512.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6933..7376)
                     /locus_tag="L1V16_002188"
     CDS             complement(6933..7376)
                     /locus_tag="L1V16_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HBN1276513.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7377..8165)
                     /locus_tag="L1V16_002189"
     CDS             complement(7377..8165)
                     /locus_tag="L1V16_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1276514.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8162..9103)
                     /locus_tag="L1V16_002190"
     CDS             complement(8162..9103)
                     /locus_tag="L1V16_002190"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBN1276515.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9280..9867)
                     /locus_tag="L1V16_002191"
     CDS             complement(9280..9867)
                     /locus_tag="L1V16_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HBN1276516.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10088..11395)
                     /gene="obgE"
                     /locus_tag="L1V16_002192"
     CDS             complement(10088..11395)
                     /gene="obgE"
                     /locus_tag="L1V16_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBN1276517.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11689..12699
                     /gene="gap"
                     /locus_tag="L1V16_002193"
     CDS             11689..12699
                     /gene="gap"
                     /locus_tag="L1V16_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBN1276518.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12784..13719)
                     /locus_tag="L1V16_002194"
     CDS             complement(12784..13719)
                     /locus_tag="L1V16_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1276519.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3808 a         3095 c         2435 g         4469 t
ORIGIN      
        1 tcaagaaaca caaactaatc cgaagaattc tttgttttgt catttaaatg taacatagcc
       61 gaaaacgaaa agtaatattg atttattctt ctaacacata aagaacagct gtctccaact
      121 tgcagacagc tgttcttatc agtcaaacaa ttgcttggat ctatgatagt tgattgtacg
      181 tattcacgac attttctact gtaaatccaa attcttctaa aattttagtg ccaggggcag
      241 atgcaccgaa atgatcgatt gtaatcgttg cgccctctgt tcctacgtag cgttcccatc
      301 caaatgatgc agcagcttcg atagccacac gtttcttcac tgatttagga agtacacttt
      361 ctttatattc agaagattgt ttttcaaaga ggtcaaagct tggcatagaa acaacagaaa
      421 catctttgcc tttttcagcc aattcttttt gagctttcac agccaaatca acttcagaac
      481 ctgttgcaat caaaatacct tctggtgttt ctccttgtga tggagaaaga acatacgcgc
      541 cttttttcac catttcatct gctacttctt ttgtagaagg caatactgga aggttttgac
      601 gactcaatac aaggatagta ggcgcatctg ttgtctccat cgctactttc caagcagcac
      661 gtgtttcatt tccgtctgcc ggacgaatca cttgaacacc aggcatgcag cgaacagatg
      721 ctagttgttc aatcggttcg tgcgttggtc cgtcttctcc gacagcaacc gagtcatgtg
      781 ttaagacgta aacaacagga gtatgttgga ttgctgctaa acgaactgct ggtcttagat
      841 aatcgacaaa gacaaagaat gttccaccgt agatacgagt tccgccatga agttggatac
      901 cattcatagc cgaagccatt gcaaattcgc ggacaccgaa ccagatgttg cgtccttcat
      961 aatgttcagg agtgaaatct ttatctgcag ccaccattgt attattggaa cctgacaagt
     1021 ccgctgaacc accccagaag cttggtatag ctttcgataa ttcttggatg acttctttac
     1081 ttgaaacacg gcttgcttga ctgcttccaa cttcataagt tggcaattct gcatcccagt
     1141 tttctggtag tttgccatca aaagcatctt caaattgttg tgctaattca ggataagctt
     1201 ttttataatt ggcaaacatt tcattccatg catcttcagc tttttgtcct tcttctatca
     1261 tcgtttgatg gaagcgggca gctacttctt ctggaacagt gaaatctgga tactcccaac
     1321 cataaacttc tttagccatc ttgatgccat cttcaccaag aggagcacca tgaacagcag
     1381 atgttccttc tttaggagca ccatagccga tgactgtttt tacttcgatc aatgttggtt
     1441 tgtctgtttc agcttttgct tcttcaatcg ctttagagat tgcttctagg tcatttccgt
     1501 ctttcactaa gatatgttgc cagccatatg cttcatagcg agcaccaacg ttttctgtga
     1561 aagcttttga agttggaccg tctagtgaaa tatcgtttga atcgtataaa acgatcaatt
     1621 tccctagttt catatgacct gccatcgaac ttgcttcttg agatacccct tccatcaagt
     1681 ctccgtcacc gcatattgca tacgtatagt gatccatcac attaaagttt tctttgttat
     1741 acgttgctgc aaggtgcgct tctgccattg ccataccgac agccattgca atcccttgtc
     1801 ctaatggccc tgtagtggct tctacaccat ctgtatgatg tacttcagga tgtcctggtg
     1861 ttttagaatc ccattgacgg aattgtttca aatcatcgat tgtcacttga tagccagcta
     1921 aatgaagcaa gctatacaac attgctgacc catgtcctgc cgaaagaacg aaacggtcgc
     1981 ggtcagccca gttttttgat gtcgttggat ttactttcag gtgttttgtc cataacgcat
     2041 atgccatagg tgctgcgccc atcggcaatc caggatgtcc tgagtttgct ttttggactg
     2101 cttcaatact taatgtacga attgtgttaa cgccaagttg gtcaattttg tcaaacaaaa
     2161 taacccctcc tattaattta ggtttttttt acctttattt cttacacttt cattctataa
     2221 gatgtcacac gaaaaagcaa tctttttcag tattttttac taaaagttgt catttcggtt
     2281 gtgtaagcct tttttctttt ggatttcttt taatttttcc ggggtcacgt cattgccctc
     2341 aggatcgacg actttcattc cttcgatatg atgacgcata ccggaacgaa aagcttccaa
     2401 atactctttg cgcaagttga tttgttcttg ttcttcggct tttgagagac cattttcctt
     2461 ctttttacgt gcaagttcat tgatccgctc tattttttca ggtgacagca tgctcagccc
     2521 tccttttact ctccttcata ttatataaaa actgaaaaaa aaacaactag ataaactaaa
     2581 taaaatacga acattcgttt gatttagcgc tttttatatg gtactattta tttatcaagt
     2641 gaaagaaggt gtaccttgtg gcccgacaaa ctgaatcaag acaaatcgaa gtcttacgat
     2701 atatccatga acaagtaacc caaaaaggat acccgccgac tgtccgtgaa atcggggaag
     2761 ctgttcagct ttcttctact tctactgttc acggtcatct tgcacggctt gaaaaaaaag
     2821 ggtttatcca aagagatccg acgaaacctc gtgcaatcga gttgacaaaa caaggtttag
     2881 aaaagattgg gattcgtcca acaactattc cagtacttgg cgtcgtaaca gctggagaac
     2941 ccattttagc agtagaggat gcttcagact tctttccaat ccctcctaat ctttcttccg
     3001 aagaaggcag tctctttatg ctgacaattc gtggagatag tatgatcaat gctgggatat
     3061 tggatggtga caacgtgatc gttcggaagc aagaaactgc tcaaaatggc gatattgtca
     3121 ttgcaatgac tgccgaggac gaagcgactt gcaaacgatt ctataaagaa aaaaactttt
     3181 tccgtctgca gcctgaaaac gacttgctcg aaccaatcat cttagatcaa gtatctatat
     3241 taggacgagt agtaggactt tatcgtagtc atatctatta attgctacta attaaaagaa
     3301 aactttttaa aaagagtttg agacgttggt ctcaaactct tttttcgccc gggttcttct
     3361 tctttcaaat ttttatcact tccctcttta caaaccgaac aaatattcgt atactaaata
     3421 tacgaacaat tgttcgcata aattaaagag gtgagaattc atgaaatcaa tgagacgtct
     3481 tggcttagta ttaactgttt tgtttttagg tattattatt ggtaatttcg gcatacgtcc
     3541 agctttactt gtgtttgttc cgttatttac tttgtggttc atgttgtggg atgaaaagaa
     3601 gtaccgtcaa tctgagcggc gcagaattca tgaagatcat ttctatcatg agccctacta
     3661 cagatccagg caatcataat aaggattgac tgctaattat tcaaaagaca agaagttaaa
     3721 cttttacggg ggtgtgacaa aaatcggtca catccttttt ttcgaataaa cggtgttcta
     3781 aagccagttt ttcggtatta agtcaaattg cggaaaaagt gattttttaa acttctactg
     3841 gtctttgctt gtttccattt ataaaaaaat agcgaccctc aaaagtcaga tagagaatct
     3901 gacttttgag ggtcgcttta aaatcgcttc tttaagaata acatcaagaa tagcttcttt
     3961 tttctgctta atattccatt aatgtaatga tgtcatatcc tttgattttg tcgcgtccat
     4021 ggagatccat caattcgatc aaaaatgcgc agcctacgac tacaccgcct aattgttcga
     4081 tcagttcgat cgtcgctttg attgttcctc cagtagctag caaatcgtca caaatcagca
     4141 cacgttgacc tggtttaatg gcatccttat gcaatgtcaa tgtatctgtt ccatattcta
     4201 atccataagt cacttcgatg gtttctcgag gtaacttccc ttttttgcgg actggggcaa
     4261 aaccgactcc taactcataa gcaacaggac atcctacgat gaatccacgg gcttctggcc
     4321 caactaccat atcaattcgt ttttcttttg cataatttac gatttgttta gtagcttccc
     4381 gataagcgtc accatctgcc atcagtgggg aaatatctcg aaacacaatt ccttttgacg
     4441 gatagtcggg aatactggca atataatctt ttaaatccac tctttgtttc ctcctaggtt
     4501 gttaaccatt tctttatggt aggaatatcg ctcaaaagca aaaattcctc aactttgatt
     4561 ttattgagcc gtcgctggta taatctgctc tcagtcaaag gatgactttc tgggctagcg
     4621 actttttgta aaacaccgtt ctctattgta acaaatttca attcaaaaaa cacctgtatc
     4681 ataaaaatta ataatttttc agggatacgc aaatattgag ctattgcttt tattttatga
     4741 cgtatatcaa ttcgttcttg agaatggatc aatttaaaca attttgcgta ctgttctctt
     4801 gtgcctaccc cattcaaata ggcctcatca ggtgaaatcc ccatcagata aacacgattg
     4861 aatgaataag accgaaaaac ttctttcaga tccgctaaat catctggaca atccataaca
     4921 actagagagt ttggttttct tttttcaatt attgccttta cagaatctag tccttcgaaa
     4981 acaatcgcag cttcctggat aatctcaggc acgaatttca acgtcgaaga atcaaatgct
     5041 aaataaaggc taccttccga cgttcggctc tgttcacgga aacgttttgc ccgccaatca
     5101 aatacttgca gaccacccac agaaaaatca gataccatca gctgcggttt cttacgcccg
     5161 ttccattcat tgatcgaaag ctttcctacc acatctacct gattattcag cagttcttct
     5221 tcttgagtac caaaaccaaa agcgaccgca tcaagctgac tcgatgcatc ggaaaggaca
     5281 aatttcagat gctgttggtt tgctccgatt cttttgatat tttctgcttg gacttgtcga
     5341 aataaaaact gaggcaaagg attatccgta ccaaatggcg ccaatagttt cagctcatca
     5401 attcgctcta ctgttacttc atttggcagc aatacttcat caattctcaa ctcaggccct
     5461 ctcatcaagt caatttgatg atcgactata tattggttca tcttctcctg tagtatagtg
     5521 acattttcac ttggcatcgt taaaccgact gctgcatgat gtcctccgaa gtaagtaaat
     5581 aaatctcgca tctggtcaag catttcaaaa agattcaagg cttcaatact acgtccagat
     5641 cctttagctg atccatcttc ttttaaagta aggacaagcg ttggtttacc cgtttcattc
     5701 attattttcc cagcaacaat gcccaaaacg ccttcatgcc atcctcggtt taccaataga
     5761 tggatatgat tctccttatt gaccatcgct aatgcttctt gtgttatctg ctctacgatt
     5821 gcttttcttt cttcattgat ctcattcaat ttttttgctt gaacggatgc ttcctcttca
     5881 tcaaacgtcg caagtaacga gacggcagga cgtggatcgc ccatccgacc gattgcattt
     5941 agtctgggag caatcgaaaa accgatcgtt gtttcgtctg cgtccctcat ttttacgccg
     6001 ctttcttcaa atagcgcctg aagtcctatc cgttctgaat gatgaatggc atcgattcct
     6061 aatgaaacaa ggattcgatt ctcatcagtc aatgaaacta aatcggcgat cgttcctatc
     6121 gctactaaat ccaaaaattc tgcaggcggt tcttccaata atgcagaagc tactttgaat
     6181 gctactccga ctcctgccaa atctggaaat ggatagtgcc ccgctggatg acgagggtga
     6241 acaatcgcat aagcgtctgg taaattctca ggtagttcgt gatgatctgt aatgatcacg
     6301 tctacaccag cttgctgagc gtatgctacc gcatcatttc ctgctacccc gttatcaaca
     6361 gtgatgatca actggattcc ttcttcgatc ttttcttggt ataccgattg gtttggtcca
     6421 tacccatgct caaatcgatt tggcaggaat acttctactt ctgcaccaag taattccagt
     6481 gtttctttca ttaccgttgc actggtgatc ccatctgcgt cataatcacc gtaaacgagg
     6541 attttttctc cactgattac agcttcttgg attcggctga ttgctttatc catatcgtgt
     6601 atcagatacg gatcatgtaa ttcttgttcc tttggatgta aaaatcggtt gatatccttt
     6661 tcctcatggt aacctctttg ccacagtaac ttaccgacaa atggagataa tttcagttca
     6721 cggatcattt ggagaaagga ttcagaaggc tctgtctcgc ttaacttcca atcaaaattt
     6781 gcttgtctca ctttctcact cctaacttag ttattatagc aaaggaaatc agcaaaaaaa
     6841 agcagaaaga aagaataaaa acagatcaga tccgctagac agatgttcag caggacctga
     6901 tcttttgtac gaccatttat gaaatatccc tattagtcaa aataattgaa gctttgtttg
     6961 ggcgattgag ttttttgttc ttccggcgct ttcaattgac tgatttgtgc ggttttcgct
     7021 tgtaactccg cctgataagc agcttccaac tccgcacgtt cgtttctaaa ctcgcgttgc
     7081 tgttcttctt ttgcttcttc aattttcttt tgaagttctg tttgatattc tgacatttcc
     7141 tgagtcagct gtttgatttg ctttttttgc tgccatagtg ttgccgaagc agtcaaaaat
     7201 acaatcagtg caccaatcag cgcagaaccg atgatcacta agatcaatgg cgcagaaaag
     7261 gaagtgaagc caaaacttac aggaacattt ttattgttca atacagcaaa aagaacaata
     7321 atcaaaacta aaacaaatcc aagaatcaca ttgctttgct ttttcaattc cttcacctac
     7381 tttttgttaa aaattccgct ggctaaataa tcaccaatcg ttggaaacag cgtataaaat
     7441 tttgatgcaa cttctaaaat aaacggttga ttgatttccc gttttggatg tctcatattg
     7501 cggacgatca tttttgccaa cttggcaggt tctaaaacga tttgtccgac tttttccaaa
     7561 tagcttccgc ttggatcagc cttatcgaag aaatttgtct cgattggacc tggattcact
     7621 gtcgtaacag ctacgccaag tggtttcaat tctaatcgca aagcgttgga gaagccaagg
     7681 actgcaaatt tcgtggcaga ataaaccgtt gattttgcag ttgccatttt tccagccata
     7741 gaggcgatat taatgatatg accttgtctt ctttctgcca tatcgatcgc aaatttttgt
     7801 gtcaaaacca tcattcctaa gatgttgact tcaaacatat cgtatgcttt tccaaggtcg
     7861 aatgtaagga agtcttcgaa aatcccaaaa cccgcattgt ttaccagaat atcgacgcgc
     7921 ccgacttctt ccatcacctt ttcatataat tcgtccacgc tttcaggatt gctgacgtct
     7981 accttgaaag cataagcctc tttgccgctc aagcgtctgc actcgtctct gacaccttct
     8041 acaaatgcca ttcttcgtgc gcaacttata acgattgctc cttgctttgc tgcttcataa
     8101 cagatttgtg cgcccagacc gcctgaacta cctgttacta aaacaacttt atcttctaaa
     8161 ttcatgcctc ttcctcctcg cgaaatggaa tctcaatgct atcaaaatct ttcataatcg
     8221 tcgtgttttc aaacacttct tgtgcttctt tttcaagctc taaagctgct tttcctaaat
     8281 atctcgcact gatatgagta agtagcagcc gttttgcctg cgcttctttt gcaacttcag
     8341 cagcttgatg agtcgtggaa tggaaatagt tgtgcgccat tcttgcttca tctttattaa
     8401 atgtgctttc atgtaccaga atatcgctat tttccgcaag cacaacggaa ttatgtgttt
     8461 ttctcgtatc gcctaaaata gtcacgattc gtcctttttt atctggacct acgaaatctt
     8521 ttccattgat cgtccgccca tcttctagtt ggatcgtttc accttgcttc agtttgccgt
     8581 acagtggtcc agctggaata cctaattctt ttagacgatc cacctgcaat tctcctttat
     8641 gatcatgttc aaccacacga taaccaaaac tgtcgatccc atgatttagt ttttttgtat
     8701 aaacagaaaa ttgctgatca gtaaaaatcg gggctgtttc atttagctca atgaatttca
     8761 gcggataact taaacgcgtt tgcgaaatac ctaaagagac ttttatgtat tcctctatcc
     8821 cttttggccc gtaaatctct aatggcgtat ccccaccttg aaatgaccgg ctgctgatga
     8881 gcccgggaag tccaaaaata tgatcgccgt gtaaatgtgt aatgaaaatt ttaccgattt
     8941 ttctcggacg aatagtcgtt cgcaaaatct gcatttgcgt gccttcgcca cagtcgaaca
     9001 accaaacttc attgcgctcg tctaaaagtt tcaatgctat acttgtcaca tttctatgtt
     9061 ttgcaggaac acctgcacct gttcctaaaa attgtaattc cataatctac ctgactttct
     9121 ttaagttcct ctttaatttt agggtaaaaa gaagggataa tcaaccgtaa gtcgagaatg
     9181 ggttcaaatt aaaaataacg ttctaaagcg atagcgtttt ctttgaaaat tactataaaa
     9241 acagcagcga acccgtttga gatcctctgc tgttttttat taatttgaag atccagaact
     9301 ttcattgtcg ttggaagttt gcggatgttt gtccttccaa gtcttttgtg cagcttcttt
     9361 cgcatgattt tcagcttctt tcgcatcatg cacatctttt tcgacatctt cataatccaa
     9421 gcgagtaatt tctccgccta attccatcat taccaattga ttcagtgggc gattgtcctc
     9481 ttcatcagca atcaagatca gtcctgtagc tccttcaccg attttatttc ctacaaagtc
     9541 gaacacggtc tgggcatctt ttatttcttt ggcatcttgt gtcgcaccga tcattcctcc
     9601 ggcaaaccat cctaataaaa tccctagcgg accacctaat acaccaacca acattccgat
     9661 taatccaccc gtagaagatt tgttattacc ggtaaagtcg ataaaatctt ctattttgaa
     9721 ttgatgtgtc ccattaggat catggctgac aactgccatc tgttctcctt taatcgaacg
     9781 aacagcatgt aactttttga tttctgaaaa tgcctgatat gcctggcttt ctacttgaaa
     9841 atttaaaatg attactcgtt tgctcattaa aaacgcccct ttcatacctt cttgttattt
     9901 attttacctt taattgaaaa ataagaaaag aaaagcactc tttttttcca ataaaatagg
     9961 gctgtgacaa aagtcgtatc acagctcctt tttccgaata aacggcgttc ttgaagctga
    10021 tcacttctgt cacaacctcc cttaaatctg aatctatatt ttttggtatt tgtttttatt
    10081 tgcttgccta ttcgacaaat tcaaattcaa actcaccgat acgtacaagg tcgccatctt
    10141 tcgcaccgcg tgcccgaaga gcttcatcca cacccatacc acgtaattga cgagcaaaac
    10201 gcatcactgt ttcatcatga tcgaaattcg tcatttggaa taatttttcg atcttctcac
    10261 cagataagat ccacgttgca tctgaatcac gatcgatttg gaactcagga ccttctggat
    10321 tgaatccata gtgtacagtt tcttcttcca gttcttcttc gtacaatggg aattctggcg
    10381 ttacttctaa caaatctgct gtagcattca ataacgcgtc caatccttgt cgagtcactc
    10441 cagaaattgg aaatactggg atgtcatcag caaattcatc ttctttttcc ttgttcagct
    10501 gttctttgaa tttcactaga ttttccggtg catccggcat atccattttg tttgccacga
    10561 tgatttgcgg acgctctagc aagcgtaagt tataagtaga taattctttg ttgatggcaa
    10621 gatagtcttc ataaggatct cgtccttcca tcccactcat atcgatcaca tgtaaaatta
    10681 ctcgtgttct ttcgatatga cgaaggaatt gtgtacccag cccaacacct tgcgaagctc
    10741 cttcaatcaa gcctggcaag tctgctgcgg caaaacttct gccatcactt gtagtaacca
    10801 ttcctagatt aggtacgagc gtcgtgaaat gataagcgcc gatttttgga cgagcagatg
    10861 aaataacgga tagtaaagtc gatttcccga cagatggaaa acctacaagt ccaacgtctg
    10921 ccaatacttt caattctagt tcgatttttc gctcttgtcc tggttcaccg ttttcagcaa
    10981 tttccggtgc aggattccga ggagaggcaa aacggatatt ccctcgtcca ccgcgtccac
    11041 cttttgccac aactagtgtt tgaccatttt caattaaatc tcctaaaaga gcaccagtct
    11101 ccgcatctcg gacagtggtt ccttgtggta ctttaacata ggtatcttct gaaccacgac
    11161 cgtgcatccc tttactcatc ccattttcac ctggctgcgc tttgaaatgg cgattgaacc
    11221 gaaaatccat caatgtacgt aacccttcat cgacgatcaa gatgacatcg ccgccacgac
    11281 caccgtctcc gccagccggt ccgccgtcag gaacgtattt ttcgcgacga aatgcaacca
    11341 ttccgtctcc gcccttgcca gctttcacat cgatcgttac ttgatctaaa aacatggaca
    11401 taattaagtc ctcctattat tcatttattt atttgactgc ctgaatttcc acaataaaca
    11461 aaagtcttac ttattttatc ggtgaaatct gattttgtct atcatttcag caaaaagatt
    11521 gtttaccttc ttcttttttt atcatttggt aaggtttcca accttttttc tgctaccaag
    11581 tataattttt tgacaaaata ttctttgcgt agcagaataa cagtgtatta attgtattaa
    11641 ttgaggatgc cgtttcacag cacccctaat aaaggaggaa cttttgatat gacagtaaaa
    11701 gtaggtatta acggatttgg gcgtattggc cgtctggctt tccgccgcat caaagaagtc
    11761 tcagatgata ttgaagtagt agcaatcaac gacttaacaa gtccaactat gttagcacaa
    11821 ttattgcaat ttgactctac tcatggtact tatcctggca cagttactgc aacagaagac
    11881 tcaatcgtag tggatggcga agcaactcgt gtttatgcag aacccgacgc aagcaaaatc
    11941 ccttgggcaa aagaaaacgg tgtagatatc gtactagaat gtactggttt ttatacatct
    12001 gaagaaaaag caaaagcgca tttagatgct ggtgtcaaac gagtagttat ttctgcccca
    12061 gctggtgcta tgaaaaccat cgtctataac gtcaatgatg atacattaga tgaaaacgac
    12121 aaaatcatct cagcaggttc atgtacaaca aactgtttag cacctatggc ttatttctta
    12181 aataatgaat ttgggatcga agttggtaca atgacaacag ttcatgccta cacttccaca
    12241 caaatgctct tagatggacc tgtaaaaggc ggtaatttgc gtgctgctcg ttcagctgct
    12301 gacaatacta tcccacattc tactggtgct gcgaaagcaa tcggcttagt tatccctgag
    12361 ctacaaggaa aattacaagg acacgcacaa cgtgttccag tcgttgatgg ttcattaact
    12421 gaattggttt cagtattgaa aacaaaagta actgctgatc aagtaaacga agcaatcaaa
    12481 aaacacacag ttgacaatcc ttcattcggg tatgatgacc gtcaaatcgt ttctagcgat
    12541 gtcattggaa caactcaagg ttcgatcttt gacccaacgc aaacagaagt aacaactgct
    12601 ggtgatttcc aacttgttaa aactgttgca tggtatgaca atgagtatgg atttacttgc
    12661 caaatgattc gcttactaga aaaattcgct aacttgtaat ttgatagatc aatcgataaa
    12721 agaagccttt gactggatcc agtcaaaggc ttctttcttt tcatccccta cttttaaact
    12781 cgttcaatga acatattggc ttaaaaattg ttggactact tgctgatatt tttcaggatc
    12841 tgtcttgtat gcttccgcat gctcggctcc ttttacaaca tacttttctt ttggtccctt
    12901 cgttgcacga tagaccttat ctaacatttc aaatggtaca aatgtatctt cgtctccatg
    12961 tataaagagc attgggcgct ggtttttctt caattgttcc actgcatttg cttcaccgaa
    13021 aaagtagcca gcacggactt ttgtcactag actcgttact tgcataagcg gaaatgctgg
    13081 aagactaaac atatcgtcta gctgataagc aagctcatca tgaacggaag aataaccgca
    13141 atcttcaatg attgctttca cattatctgg tagtttttct ccgctagtca tcataactgt
    13201 tgctgctccc atgctgacac cgtatagaac gatttcttgc gattttccat tgttttctag
    13261 cactttgttt atccactgta catagtcttt acgctctggc catccaaatc caatgtaatc
    13321 cccttcgctt tttccatgtc ctcttgcatc aggaacaagg acattgtaac ccatatcatg
    13381 aaacatcttt gcgtaattgg tcatcgtttc agcgtttccc atatagccat gagccacaag
    13441 agctgttttt tcacttttcg tttcagcagg aagataaatc gctgataatt tcagaccgtc
    13501 ttttgaagtg atggtccaat cgcttcggtt ttcttttgaa ctaaaccatt tatgtgcatc
    13561 cgtttctttg gatgtctgtg ttgtaccagg tgtatcttcg tctaaaaagt ctttctcaga
    13621 aggcacaaca gcataattat aaaaataatt ccctgcaaac actaacgcaa caatcagagc
    13681 taaagcgacg cctaaaagga ttttcatcca aagtttcata aatcatccat ctcatttctc
    13741 ttttttcata taaccttgaa ttagtataat caaagaatct ctactatgca atgttcattt
    13801 ttataac
//
LOCUS       DAFLWQ010000074        13732 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.077, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000074 DAFLWQ010000000
VERSION     DAFLWQ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.077"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            131..1558
                     /locus_tag="L1V16_002195"
     CDS             131..1558
                     /locus_tag="L1V16_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1276520.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1650..2015)
                     /locus_tag="L1V16_002196"
     CDS             complement(1650..2015)
                     /locus_tag="L1V16_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBN1276521.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(2012..2377)
                     /locus_tag="L1V16_002197"
     CDS             complement(2012..2377)
                     /locus_tag="L1V16_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBN1276522.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2569..2817)
                     /locus_tag="L1V16_002198"
     CDS             complement(2569..2817)
                     /locus_tag="L1V16_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276523.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2816..2944
                     /locus_tag="L1V16_002199"
     CDS             2816..2944
                     /locus_tag="L1V16_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HBN1276524.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            3001..4695
                     /locus_tag="L1V16_002200"
     CDS             3001..4695
                     /locus_tag="L1V16_002200"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HBN1276525.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4699..4818
                     /locus_tag="L1V16_002201"
                     /pseudo
     CDS             4699..4818
                     /locus_tag="L1V16_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            4795..5091
                     /locus_tag="L1V16_002202"
     CDS             4795..5091
                     /locus_tag="L1V16_002202"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276526.1"
                     /translation="MQAFEHRLPRGCEKAALHQVIRTPKLKLLLMFLTWLDLLPQMQA
                     FEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQAFEHRLPRGYEKGV"
     gene            5469..6602
                     /locus_tag="L1V16_002203"
     CDS             5469..6602
                     /locus_tag="L1V16_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HBN1276527.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6633..6953
                     /locus_tag="L1V16_002204"
     CDS             6633..6953
                     /locus_tag="L1V16_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HBN1276528.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6982..7446)
                     /locus_tag="L1V16_002205"
     CDS             complement(6982..7446)
                     /locus_tag="L1V16_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1276529.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7577..8830)
                     /locus_tag="L1V16_002206"
     CDS             complement(7577..8830)
                     /locus_tag="L1V16_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1276530.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(8859..9176)
                     /locus_tag="L1V16_002207"
     CDS             complement(8859..9176)
                     /locus_tag="L1V16_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBN1276531.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(9202..9522)
                     /locus_tag="L1V16_002208"
     CDS             complement(9202..9522)
                     /locus_tag="L1V16_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1276532.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(9986..11401)
                     /locus_tag="L1V16_002209"
     CDS             complement(9986..11401)
                     /locus_tag="L1V16_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1276533.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(11418..12734)
                     /locus_tag="L1V16_002210"
     CDS             complement(11418..12734)
                     /locus_tag="L1V16_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1276534.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(12884..13582)
                     /locus_tag="L1V16_002211"
     CDS             complement(12884..13582)
                     /locus_tag="L1V16_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBN1276535.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
BASE COUNT         4364 a         2787 c         2359 g         4222 t
ORIGIN      
        1 tttataacat aaaaaacctt ttttaacggc atttatatgc tttttcagaa attaactgat
       61 gatttcaaaa agaaaacatg tcataatatt tcccatattg tgcaaaaaaa tacaaggcgg
      121 aggctctact atgattgaag aatatattga gaaaaatatt ttaagacagc tgtttttatg
      181 tgggcaattc tatgtaaata aagaagtcaa tctagaaaag ctctccaatc tcctgcatgt
      241 ttgcaaaacc actttactca atgatatcaa taacataaaa aaagaatttg aagaacagat
      301 cgcttataca catcgggaaa aggaccgtta cactttatat ttttcagaac atatacctcg
      361 atgcaagatc atgcagcaat tgtctcaaaa ttcgttgttt ttaaaaactt gtctgcttta
      421 tttggaagaa gatgaacctg attatcttca attaactgaa tgtgaattca tctctgtcag
      481 caaagcttat tcattaaaaa aacaagtatt agcttatttt aatgactgcg ggatcgaaat
      541 cgaccgctac tcccctcgat tcactgaaat ggaaagacgt ctgctgcttc ttaatgtgtc
      601 gtatcgttta ggcggtttta attcttggga gctacctgaa tcgttttttg aacgtgccga
      661 tcgtttcatt gaatccgtaa cggaaaatag tggcagattt tatgataaag aaaataaaga
      721 aatcttatcg attggttttg ctatcagttt cctacgccag caagtgtgtg ctgtgacaat
      781 agattcaaaa tttatcgaag aaatcaaaaa acgtcctatt tacaattatg tcgaatcagc
      841 atgggaaaac actgatttcc aaacctatta taaaaaagaa gaattcgcct ttattttgac
      901 actattcaat ctttgtaatt atggtttcca ttcttatcag ttgattgcgg aagactttca
      961 acagctacac caagtgttta ttgacaatac tcccgaaata aaagaactag ttgctacctt
     1021 tgaatctcac ttcaatcaag aattattcgg aaaccaaccg ttcgaacgtg cgctgattca
     1081 tctgatgcgt tcggcttggg ataactatca attattcatg ccagaaaaat tttatctttt
     1141 aaatgaggaa cagacaaatt tatataaaga agtccagaca attttttcca gctggtccag
     1201 ccagttacct tatgatctac ggttgaatcc taattgcatg cgggcttttg tgatcgaatt
     1261 gagcggaatt ctccgtctga caaaagaaca tctgactatc tatatcgtca caaattcgga
     1321 tgttcattat ctgatttatc gggaagcctt ggaagctgta actactttcg attttcaagt
     1381 tgcaccaaca atttattcaa gtatatctga tataaagaag tatgcgcagc agtcctcaaa
     1441 ccgggtatta tgtgaacgta cattatatac accagatgcg gtccaatatg aaaatattat
     1501 tcctatttcg atcaatacga tcgatcgagc tatcatttca gctgtgcaaa acaaataagg
     1561 ggctgtgaca aaaatcatgt cacagcctct tatttgttga agatgcccat ttctgtaaca
     1621 atctcttgat acacgtcagg ctcacaacct cacttatttt ggacatctac gggtccgatc
     1681 tctttattta aaaaataaga aatgatggtt cggataacta ccaacgccgc tagttggaaa
     1741 atatcctgca aggtaggttt gataatcgat tcgatgatcc cagctgaaac aagaatttcc
     1801 aaacttagaa gtatatagcc tcccaacatc tttttaatag cattgttctc gctgactcgg
     1861 tcgctttgca cttttgtatg gacaaataaa tatttcaaaa aatccttgat tgatagacaa
     1921 acaccccaaa ccaataaaca gatagcaaag atatcaagtc ccagtacaag tttttcgaaa
     1981 tatggaagaa gaaactgcat caactctgtc gtcatcctac ctctcctctt ctttgttttt
     2041 ctttgtcttc tatttcctga ttcaagaaat aagaaatgac tgttcgaatg ataataataa
     2101 gtgcaagctt caaaatatct gtccaagtcg gcttgataac tgactcgatg atatcagcaa
     2161 cgactagtac ttccaagctt aacaaaatat aacttgctag cagttttctt gtatctgcat
     2221 tacgagtatt acgttctgca tagtttttct tgacatgaga ccaatcaaaa agtttgaata
     2281 gaacaagaac gatcccgaca attaagatac cgatagaaca aatatttaaa atagcaatga
     2341 tccattctag aaattcaatt aaatttgagc gaaacatata cgctacctac tttcttttaa
     2401 tttgttccta ttcttttatt gtaaaagaaa gttaccttgt tcgtctattt aaaagttgtt
     2461 ctaatgataa cggttcgctt aaatttttct ttttcactct cccatttttc tccctccatc
     2521 cataaatcgt ggaagtatcc aaaacaacgt agcaagttaa aataaggctt agtccgtcat
     2581 cagcttttca aagaagcact gtctcggtgc tttttttgta cccaaatttc taaaaataga
     2641 accatacacc tcctcaaatc ttttcttctt acctacccta tttttattta caggaaaatc
     2701 agacacttct tcttttttgt caaaatttcc tttttcttct cgtcctatca tttggcattc
     2761 taataaaaac gaactatcct tggatataga aagagaaaac aaggaggcgt ttttcatgag
     2821 taaaaaatta atcaaagtcg gcatcggttt aggtttgctt gcccttggcg ctgcatatct
     2881 aggaaaaaag acaggactat tcgaagatga cagtcattta tatgatgaat tcgaatcaat
     2941 ctagcatcct atttagttga atcactacgg acatacttgg aagacattgg aggaatcaca
     3001 atgagaaaaa gtaaagcaat aatgattggt gccggtattg ccaatatggc agcggctgtt
     3061 tatttgattc aagaaggcaa atggaaaggg gatcagatca ccttttattc attggatgat
     3121 cacggttcaa atgatggtgc accgaccgac actgtagtgg atgaatattg gaataaaaac
     3181 catccattag aaaaccaaaa aggctatatt gctcgaggcg gtcgcatgct taattaccgt
     3241 acctatgtag atttgatgga tctgttaagt cgaatacctt ctgttactga gccagggatg
     3301 actgctgaag aagatacgag agattttgat gcaaaacacc gaacctttga caaagcacgt
     3361 ttgatggaag gtggcaaagg aatcattgat ggcggaaaac tgggattcaa taataaagac
     3421 cgtattcttc tgactaaact gattgctatg cctgattcag aagaagaaaa actagacaat
     3481 atcactatcg aagaatattt caaagatgat ccacactttt ttgaaacaaa cttctggttt
     3541 atgtgggaaa caacatttgc tttcagaaca cgtagttctg ctcaagaatt gcgtcgctat
     3601 atgcatcaaa tgatttatga attcactcaa atcgaacatc tagtgggcgt caatcgaaca
     3661 cgttacaatc aatacgaaag tattatgctt cctttgatcg agtacttgaa agaacaagga
     3721 tgcaaaatca ttttgaaccg ccgtgtcact gactgggaat tcaaagaaac accgatgcaa
     3781 gatgaaatca ctgtgactgg tttgaaaatt accaatacac tgactcaaga agaagaatac
     3841 gttgtggtcg atgaagatac agcagttatt ttcactaatg ggtccattac agattcagct
     3901 actttaggag attacgaaac accagctgta gaaaatatgg attatggtgc agcttctagt
     3961 ctctggaaaa aagccagtga acgtttctac aacttgggaa atcctgacaa attctttgct
     4021 gatcgagatg caagcgaatg ggtcagcttt accctgacga cgaaaaacca tttgttgttg
     4081 aatgaaatca cccgtatcac gactcaagaa ccaggaaatg ccttgaattc atttatttca
     4141 accacaccga tcacgccgtt aggccaaaaa gatgtcaata tgtctatcgt cgtgcatcat
     4201 caaccgcatt ttacgtctca gaaaccaaat gaaacagtta tttggggtta tttcctttat
     4261 ccaagacgac gtggcgaatt tgtggataaa cagtatatta aaatgaatgg aaaagaaatg
     4321 ctagaagaac tgattggaca actttcaaaa gtagatcctg gaccagtgaa tattcgtgaa
     4381 aaagaaacag aaattttcga cagcgtaata aataatatcc ctgtctatat gccttatgct
     4441 tccgcgttgt tcaataatcg tgccaaaagc gatcgaccaa aagtcattcc taaacattcg
     4501 accaatctgg cctttacagg agaatttgtc gagcagcctt atcagatgat ctttactgaa
     4561 caaagtgctg tacgttctgg agaaatcgct gctttccatt ttgcgggtat tcctatgtcc
     4621 cgtcttgtca aaacaccgcg ttacgacaaa gatattccta ctctagctcg tgccgcaaaa
     4681 aaaatgtttg aataatcaag aggttgtgaa aaagctgccc tgcatcaagt aataagaaca
     4741 accaggctaa aacagcttct tatgtttttg atttggttgg acttattacc gcagatgcaa
     4801 gcttttgaac accgtttacc aagaggttgt gaaaaagctg ccctgcatca agtaataaga
     4861 acacccaagc taaaactgct tcttatgttt ttgacttggt tggacttatt accgcagatg
     4921 caagcttttg aacaccattt accaagaggt tatgaaaaag ctgccctgca tcaagtaata
     4981 agagcagcca agctaaaaca gcttcttatg tttttgactt ggttagactt attaccgcag
     5041 atgcaagctt ttgaacaccg tttaccaaga ggttatgaaa aaggcgttta gtttcgagta
     5101 tgaagaaaaa ttttgtgaaa atggttcctc acgtttttgc ataaatttga cttaataccg
     5161 agaaactgat cccttctgtc ataacctctt tttatttatg tctgtttctt tttgaaaaca
     5221 actatttttt caacgtttac tctcttgcca atccaacatc atctaacgga tacaactatt
     5281 tcaatgatta ccattacact aaaaaatcgg aaacacacct ctccgaacac aaatacataa
     5341 gactatagaa tgtttcattt aagaaaaaaa gcgtttcatt atcaaaaagg taagatctcc
     5401 tttaaaatga aattatctgt agtactaata atgcagacaa ttttatgaat ctgaaaggag
     5461 catctccaat gaaagcagtc acttggcaag gaaaacagaa aatggaaatc agaaacgtag
     5521 atgatccaaa aatattagaa ccaacagatg caatcatccg tatcacagca acagccattt
     5581 gcggctccga tctgcatctt taccatcatg gtgaagcagt tttggaaaaa gggtatgttg
     5641 taggacacga accaatggga atcgttgaag aagtgggatc tcaagttcaa acattgaaaa
     5701 aagggcaacg tgtggttatc ccttttaata ttagttgtgg tcattgtcat ttctgcctga
     5761 atcacatgga aagccaatgt gatgaatcaa atccagatca gttatatggc gggcttttcg
     5821 gatttggcaa gttgaacggt aatcattggg gtggtcaagc ggaatatcta agagttcctt
     5881 atgcagactc tacttcattt gttgtaccag ataatgatct tcctgatgaa aaagttttat
     5941 ttctatcaga tattttgccc acagcttatt ggagcgttga aaacgcagga gtaaaaaaag
     6001 gcgatacagt tgtgattcta ggttctggtc cagtcggtct attcgctcaa aaattcgctg
     6061 ttatggctgg agcagagcgc gtaatcgcag tagatccagt acagcaccgt ctagataaag
     6121 cggctaatta caatggggtt gaaacttatt tcttagaaga cacggcacaa gctggaacag
     6181 aattgtatga actggctaaa ggtggcgcag atgtcattat cgattgtgta ggaatggacg
     6241 gattagagcc tgtcaaagaa aaagcgaaaa atttagtaag cttacaaagc ggcacaatct
     6301 ctccattaca gatggcatcg caagctgtca aaaaatttgg aacagtccaa gtaactggtg
     6361 tttatatgac tccagcttct tcttacccgc tgcaagaatt ttttatgcgg gatatcgctg
     6421 tcaagcatgg acaggcacca attatccatc taatgccaaa aatttacgca atgattgcag
     6481 aaggactatt cgatcctaca caaatcatta ctcattcgct gccactatca gaagcagcac
     6541 aagcatatga gatctttgac aaaaaagaag ataaaaatat aaaagttgtt ttgaaacctt
     6601 gaattcagta aaaaatacag gtgattttct ttatgcccaa aatcaaacga aatacccatg
     6661 agatcgaaat aggaaaagaa gaagatatcg aaatacgagg acgtcgcttc cgcttctatt
     6721 tccaaaatcg ttacacattg atctcactgg ctgtcgattt attaaccggg attttctata
     6781 tttttggaag ccttgcttcc ttaactaaaa tccccgatcg atatggcacc tatttttatt
     6841 tggctggtgc tattttcttg acgattcgtc ctattctcag aatcgtaagg aacattttta
     6901 tttacgacga aaaaaaagca atgaagagaa caagcaaaaa aaaagaggca tgagaatttt
     6961 tcaaatctca tgcctctttt ttcaccctat cgtatcactt tgatacagac gagcggtcgt
     7021 cccactttct tccttgacca ttgtcaaaaa tgtccactcg tatcgttcat aaaacgtggt
     7081 atgatctgta attaagtaaa gtttttcgta cccaagttga tgcatttctt ttctgatttc
     7141 cgctaatatc cgcttggcta tcccctgctt acgcttttcc ggttcaacaa acagggcaca
     7201 aagatttggt gtcagatcag ggcggttatg gaagtcgttt tcaatgacgc ccgctcctcc
     7261 gacgatggtt tctttttcat ctaagaccac ataccattga ggaatacttt ccttattagc
     7321 gattccagta cgaatacttt cctcatacac aacagcagga actccccatt ttgatgaaaa
     7381 ccaattcgcg ctttgtttta ctaattctgg gtgttctctt aatttgatcc agttatatgt
     7441 aaccaatgtt taaacctccg actaaaataa aacgtttaca aaaattatac aagtctttat
     7501 gaaaattagc aatgacaaca atagtgatgt aaaaaaaaaa cggaaaacaa tcacttgttc
     7561 tccgtttttt gattaatcaa gcatctaaag cttcttttct tctttcttgg atcgtagcta
     7621 ccttgacgaa cggtagatag atcaaaatag aaagaaccaa attgacagcg gctagtacac
     7681 cacctgcaat actttttgtt gccaatacac cgccaataat tggtggagtt acccatggag
     7741 gcataacggt agctgctggc actaaacctg tagaagtcgc aaagtaagca acactaacta
     7801 agaccattgg tgtcaaaata aatggaatga acatgatcgg gttcaacacg ataggtaacc
     7861 caaacatcgt tggttcatta atattgaaga cacctggcgc aatcgacaag tttgttacaa
     7921 ccatatatgg tttgttttta cgtcctacta aataaatagc taacagtaaa cctaaagttg
     7981 cacctgttcc tcctaagttg acaaagctgt caaagaaagg tttgttcacg ataaacggtg
     8041 cgctatgccc agctgcgatt gcattaacgt ttgcttcaat ggctggcgca ttgattgttt
     8101 gcatcaaagg atcgaccata ttcgctccgt gtaaaccaaa gaaccataag aatggtgtga
     8161 taaatgcaag cagtaaggca gatggataag agtttgcaag tcccataaat ggttcttgga
     8221 ccactgtata gaaagaacct acgatatcat caacaccgaa tgcagcaaaa attgcagcaa
     8281 ctaaagcaaa cgcagagata gtgatcattg ctggtagtaa tgaagcaaat gcttttgcaa
     8341 ctgccggtgg cacaccatca ggcattttga tgatcaattt ttcatttccg cttaaacgta
     8401 caaagatttc tgttgaaata atcccaacaa taatagcaat aaacaaaccg tttgagctca
     8461 tacctaatgc tccgcctaaa gcgaagaaag agcctaaaga aatcacacct gcggaaacac
     8521 cgtcttttcg gtagccgtta gctaaatgat aagcaagcaa gaaagcaatc aagacagaaa
     8581 gaatggcaaa tgtaccgttc caagcagcag ccccgaatcc tttccatgat tcaccaccaa
     8641 aaattgagtt catcaattct tggaacccgg gaatcggtaa gttattgatc attactgcta
     8701 atgctcctaa gatcattaac ggcatactca ccataaatga gtcccgaatc gcaactaaat
     8761 gccgttgtgc accaattttt gatgctacag gtataaaatg tttctccata aatgcaacaa
     8821 atttatccat aaatcttccc tcttttcttt actgtagatt acgcgttcaa tcgacgatac
     8881 agatcaatga tctcttttgc taaatctgta aaagctatag atgtcatcag atgatcttga
     8941 ctgtggaccg tcaaaagcgt gacttcaacg tgatttcctt gtgcttcttg tgtcagcatc
     9001 tctgtttgag agtgatgtgc ttggactaaa gattcctctg catctttgat tttttcatct
     9061 gctaaagtga aatcaccttt tttcgcagca gcaatcgctt ccattgcatc gctttttgca
     9121 tttccgccaa acatgatcag acccatgatg gcttctagat ttttttgatc ttccatttat
     9181 tgtatcctcc gataattttt attatttgtt tattagtttt tctgcttggt cgagtacttt
     9241 ttcaccattc atcatgccat agtcagccat attgattaca tctaaaggaa tgcctttagg
     9301 tgctagcttt tcagcaaatt gattttgcat aaagcgtact tgcggtccta aaagtaaaac
     9361 gtctacattt ttagattcta gttgattatc cgcatctgaa gcagatacag caaagatgtc
     9421 tgcttccatt ccttttgctt ctgctgcctt ttgcattttt gtgactagga gacttgtact
     9481 cattccagct gaacatacaa gcatgattgt tttcttttcc attttaaaca cgttcctttc
     9541 tatacttaca cttgtatata agcaagtagc gtgccaactt taaaagcgct ttaaaaagtt
     9601 gatatcatca catttaaggt ctataccaag ttgcatacac actaaaaaag aaagcgcaca
     9661 ctaaacacac aaattaattt ttattacctt ttttctttta acgtgcacaa aaaaagttgt
     9721 gacacaaaac ttgtcacaac ttttttcaaa taaacggtat tcaaaagctt gcatctgcgg
     9781 taataagtcc aaccaagtta aaaacataag atgttgtttt tactttgcta ttcttattac
     9841 ttgatgcagg acagcttttt cacaacctct caataaacgg tgttcaatca gctgaccctg
     9901 ggtattagct caaaacgctg gattcacaac ctcttttatt tcaaataacc agtaaataca
     9961 atgaacatct acaaaaaact tctatttatt tatagatttc gtcaggcaaa tccaattctc
    10021 tcttatcaat caaagtctga taccacgaag cagatttttt caatgttctg cttcgttcat
    10081 cgttcaattc gattcgaact aatccatatc gattcttaaa tgcattcatt ggtgacacac
    10141 agtcagtgaa tgcccataac atatagcctt cgcaatttgc gccttcttct gttgctttga
    10201 tcaagtaatg caaatgctgt ccgataaatt cgatacggta atcatcttgc acgattcctt
    10261 tctcatccat atactgttct tcatattctc ttcccatacc gttttctgtt atcagccaag
    10321 ggatattatg ataattttct tttagataca tggctatatc atacatgatt ttcggataga
    10381 tttcccatcc cctggaatta ttcattttct tcccaggtaa atcaaagact tcataatatc
    10441 gttcaggatg gaaaggtgtc tcttcattcc attgataacg aggggcgcga acgcgtttag
    10501 gataatattg attgattcca aggaaatcta ctgtatgatg ctgaatcgtt tctaaatcct
    10561 ctgttgcagg atcgaaataa atcgattgtt tttgacacaa ctccaggaac tcttctgtgt
    10621 agtatccttt taccatcgga tcaaaaaata ctcgattata aaacaaatca tacatataag
    10681 cagctttttg gtcttctgga gaattggatc gagcatagac catttcagga tttaaaatac
    10741 agccaatcct tccaccataa tttccgctgc ggtaaatctc tactgcttta gccgttgcta
    10801 aaactttatg ataattccac atcatccact tttttgtgtt ttgttcatgc ggccagcgaa
    10861 cagcatccaa atagcaacgc gtttggggaa cgattggttc gttgaatgta aaccagtttt
    10921 ttaccctatc accgtaacga tcaaaggcaa tttgagcata cttagcataa aaatcaacta
    10981 cttttcttga agaccagcca tcatattttt ccaaaagaaa agctgggact tcataatgtt
    11041 ccaaacaaat catcggttct acgtctgctt cgatcaaaga gtcgatcatt tcacttatat
    11101 gctgagcata ttcttcatct actatacagt tctcataatc agtaaaaaaa cgagcccaat
    11161 tgatagaagt ccgataatgt gtcagatgga tggatttcat cagatccaca tcctgctggt
    11221 attgttccat aaaattagtt gctacggctg ggccataccc attatgccaa acaaaatgtt
    11281 catttttata ccagctatct ataaacgaat cctgtccttc tttttttcct ttccaacctt
    11341 ccgtttgcca agcagaagat gcagcaccaa gaataaaatt ttttggaata gtaattttca
    11401 tgatttcctc ctgtttttta gatcccatca ttttccacac gatttgctac ttttacaaat
    11461 ggcagataga tcaaaataga aacaataata caaacaagtt gcgtaataac tgcaccgata
    11521 tttcctgctg ttgccagata agcattgacg atcggcggca ttggccaagg gaccattaca
    11581 actgctttcg ccgcaaatcc taaagcggtt gcaaaataac caatcgttcc agtgataaga
    11641 ggcgttaaga taaacggaat agctaaaatt ggattcagca tgatcggcat accaaaaata
    11701 actggttcat tgatgttgaa gatcccagga gcaagggata acttggtgat ttgtttcata
    11761 tcttcccgtt ttccaactaa caatactgca atcagtaaac cgatcgtgac tccagacccg
    11821 cccatactca tatacatatc ccaaaatggc atagtaataa tgttcggtac ttcttttcca
    11881 gcttcaaaag cttccgtatt tacagcaatt gccgctaaaa gcaacggttc ccgtatcggc
    11941 ttcaccattt gatttccatg gataccaatc acccaaaaga cttgcgcaat aaacatcaat
    12001 agcaaaatac ccggtaaccc ttgtacgaca ccttctaatg ggcgttgtac gacattgtaa
    12061 atgatatcat aaaggtacat tcctgtaagt tctttgatga taaatcccgc agccgcgata
    12121 cccgatacag tcagaatcgt cgggaataaa gcagaaaaac tagcagaaac attcgttggc
    12181 acggtatcag gcattctcag ctgtagtttc ttctgtttcc tcaaccagca ataaagttca
    12241 atagaaagga tggagaccaa cattcccaaa aataaccctt tcgtatctgt atattgttta
    12301 gccaatacgt tttctactat aacagtctga ttttcattca ctaattcata aacagttgga
    12361 ttaacagata aataagacat cactgcgatg ataccaggga atacaccatc cactttattc
    12421 agcttggcta attcgatccc tatcagaaaa acagcataga tggtcaagaa acttagtgtg
    12481 acatagctga tggcagatgc gataggcttt aattcttcta aaaaacgcaa gaaacttatc
    12541 tgtgctaagc cattttccga gtcaaagacc attgctgaaa acaatgtgcc aaaagcaccc
    12601 gtaataatta ccggaatcaa tgcagcaaat gcgtttttta tcaccatgat ataccttaaa
    12661 ttattgattc tcgttgccac gttccctaaa acattggcta atttatccat aaaactcatt
    12721 ccagatcccc tcattcctgc ttcttctcct tgacgtcatc tctttttgtc tattagtcag
    12781 cgcttacatt tcgatgaaca gaaactattt actcctcttt tttaccaaat ataaaacaaa
    12841 aattcatctg atgtatttat cataaaatac atcagatgaa ctgtcaatta gtttcttttt
    12901 ctcctattat tttctgtaat tctctccgat ttattgccat atggacagtc attgcatcaa
    12961 acgcagcaag tgcattccgc ctttcgatgg cctgaacgat ctctgtatga atatcgatcg
    13021 tctcgatttt cagatgctgg atatcataat ttttattaaa caaagcaatt gattcattaa
    13081 tgattgggat aatatgcagc aaggctacgt ttccgctagc ttctgcaatc atcgtatgaa
    13141 aatcgatgtc taattgaaca tgttcttgtg tgccttctcg aaaagaagtt tcaatctttt
    13201 gcgttaattt tttcatttgg acgatttgat tcttcgttgc atattccgct gccaaacctg
    13261 ccatcttagg ctccaataaa tatctcagtt caaataagtc tcgtatcatc cgatcctgat
    13321 cttcaatcaa agaaaaaccg agtgggtcat tggcaatccc tcgcttatca ctgacaaatg
    13381 tccccgctcc ttgccgaact tcaaggatat tcctggaagc tagagcccgc acagcttctc
    13441 gcaccgtgct tcgccccacc tctaaataat cggacaattc atattcattc ggcagtttat
    13501 ctcctacttg caactgcatt tcctttaaat atctaaggat cttgtcagta gttacttcta
    13561 ctagggtttt attttcttcc aaaccacata cctccttttc atctgatgta ttttttcgta
    13621 attattataa cacgtttgaa tcatctgatg attttttgta tacaaaattg attaatccgt
    13681 tcatagacat acaaacgaag aagatattta ccataaaaaa gactaggata aa
//
LOCUS       DAFLWQ010000075        13706 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.078, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000075 DAFLWQ010000000
VERSION     DAFLWQ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.078"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(279..494)
                     /locus_tag="L1V16_002212"
     CDS             complement(279..494)
                     /locus_tag="L1V16_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276536.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NSVVLKQFWLNNFSYKDFIKEKANTLY"
     gene            complement(546..1460)
                     /locus_tag="L1V16_002213"
     CDS             complement(546..1460)
                     /locus_tag="L1V16_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276537.1"
                     /translation="MNNNEKILHVLDSFEIIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKNAMELNEERRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPSNSGIGIVLKAIDEEEIEAFIPPEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCESYGVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     EARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNATNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKKAE"
     gene            complement(1460..2359)
                     /locus_tag="L1V16_002214"
     CDS             complement(1460..2359)
                     /locus_tag="L1V16_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBN1276538.1"
                     /translation="MWTVTLPFQPVSAPRPSARRNAADETNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQDLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            complement(2359..2946)
                     /locus_tag="L1V16_002215"
     CDS             complement(2359..2946)
                     /locus_tag="L1V16_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276539.1"
                     /translation="MENNNDIRHFSIGERVTTVSELSKDYRDKEGTIISLNKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNNGSHSIEKAILVYPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITSKEAKIEDVLTVRELQSLIEYRNKQITNPEYLRKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDTFKKIYLKEIKKD"
     gene            complement(3110..3301)
                     /locus_tag="L1V16_002216"
     CDS             complement(3110..3301)
                     /locus_tag="L1V16_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276540.1"
                     /translation="MVVNKEKVRKYVTLKIASVKYLEKRAKEEERARGKKVTVSELLE
                     ELIENDQTIRRAFTNRSIR"
     gene            complement(3374..4276)
                     /locus_tag="L1V16_002217"
     CDS             complement(3374..4276)
                     /locus_tag="L1V16_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276541.1"
                     /translation="MLLTLLGYLCLILAFFGAIAIIIGQFQTNNPIMRNIGIGIVIVT
                     FIVFNATKIFGSNDKQFGISGVNNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDGK
                     KASDDVLATIKPSQSQFEVFYTVKENSPVHKLTLVFNVDGEEYYKDVKINKTSTKKII
                     ESAKKEVATEESTTESSSTVEAELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQMINVTLFNSVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGADLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            complement(4293..4769)
                     /locus_tag="L1V16_002218"
     CDS             complement(4293..4769)
                     /locus_tag="L1V16_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276542.1"
                     /translation="MPKRKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRILEWLNTNTDQEPLRVISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSKDSKSMRDLLITYLNEHEFEQTKTKKKNKE"
     gene            complement(4785..5384)
                     /locus_tag="L1V16_002219"
     CDS             complement(4785..5384)
                     /locus_tag="L1V16_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBN1276543.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLHSNIVSMGLSGGIFGWIALFAIAYIRFDSKKHLLLSVFVLLIIGIL
                     LVSTFESGEANVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            complement(5388..5441)
                     /locus_tag="L1V16_002220"
                     /pseudo
     CDS             complement(5388..5441)
                     /locus_tag="L1V16_002220"
                     /inference="COORDINATES: protein motif:HMM:NF019230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5943..6422)
                     /locus_tag="L1V16_002221"
     CDS             complement(5943..6422)
                     /locus_tag="L1V16_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276544.1"
                     /translation="MLELFEANRTGFNQKLEVGETIEYKDKNYIIIGIYNTRINRIGD
                     PRITSDLVCQSVNYSPDLTSRYKKYVLLEYRHKITDEIGVNNTRNIFKIGTVIPYSNN
                     EEKIFYQIYGIEKFEYEHVDLLVTYQMRLIEPWSQAEIDKAVKLNRLSKFNVLGNAF"
     gene            complement(6441..7070)
                     /locus_tag="L1V16_002222"
     CDS             complement(6441..7070)
                     /locus_tag="L1V16_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276545.1"
                     /translation="MIIVSSFLRWLTPYKYTDEVVVKRAKKRDKKAVLTPKQMLDHGI
                     LGVKVLEVNKPFESNSAREKLLGAEADVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLRPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSNQNRVQINKFEKKVRK
                     FNDRKTILWFADICKQPDGTAKWEAVIFDENGKKVMSETWHDKAKFVWQ"
     gene            complement(7067..8443)
                     /locus_tag="L1V16_002223"
     CDS             complement(7067..8443)
                     /locus_tag="L1V16_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HBN1276546.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISEMPHMLVAGTTGSGKSVLLNEILVTVMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGLQNITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMLIKLVDGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAETRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANPSSKEPSIEKKSAFAIKLEKNKEEKVEQGAKTLEKLQAEKLEKVLRALGK
                     ADPEPQTSNNTNNKQPIASKTKPKANDPKGSENVVITTDKSEKKQINGSTSPIMQKML
                     KAKKQVHK"
     gene            complement(8523..9785)
                     /locus_tag="L1V16_002224"
     CDS             complement(8523..9785)
                     /locus_tag="L1V16_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276547.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALVVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETERATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            complement(9798..10145)
                     /locus_tag="L1V16_002225"
     CDS             complement(9798..10145)
                     /locus_tag="L1V16_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276548.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            complement(10165..11034)
                     /locus_tag="L1V16_002226"
     CDS             complement(10165..11034)
                     /locus_tag="L1V16_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBN1276549.1"
                     /translation="MKKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAVNSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            11355..12782
                     /locus_tag="L1V16_002227"
     CDS             11355..12782
                     /locus_tag="L1V16_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
                     /protein_id="HBN1276550.1"
                     /translation="MMRKQSIEGRNQFAMLTIDDLVPKDHLVRKIDAAIQFDFIYPIV
                     ESTYSTYGRPSIDPVVLIKLVFIQYLFGIRSMRQTIKDVETNVAYRWFLGYSFEDPIP
                     HFSTFGKNYVRRFRETTLFEDIFSHILEQAVKAGFVTEDNLYIDSTHIKANANKHKFT
                     KEMTYGQAKAYQDELEDEINKERIAVGKRPFTWDTESELSLQKISHSDPESGYYVKGE
                     REKQFAYSAHTSCEDNGFILSTLITPGNVHDSQVAIDLVKQSKRAFPNIKRVVADAGY
                     KTPKFVHFLSHLKLYPILPYTAPHGVKGMFRKKDFVYDAYFDCYLCPNNQPLLFSTIT
                     RDGYRTYKSNPKFCVSCPLLENCTLSTKHQKIVTRHIWADLMDELEHQRHTALNREIY
                     KKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLTFAAMNLKKLATWLWKTKKPM
                     AFYFKIMQRLTKRSGLITNSFLSTI"
     gene            complement(12799..13605)
                     /locus_tag="L1V16_002228"
     CDS             complement(12799..13605)
                     /locus_tag="L1V16_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276551.1"
                     /translation="MRGDQTMSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWIS
                     AVGEENIEFEIKNMDDLKAKFPFIASKLSQVAEDKSWNELVSFSEKIYDITQEDECVS
                     WEMNNQYKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYA
                     EYLKTERDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALS
                     QYSSDEEVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
BASE COUNT         3925 a         2724 c         1901 g         5156 t
ORIGIN      
        1 catctttaaa gaaatacgat caaaaaacat aattcccata ttatttgctc gttcaacaat
       61 ttgaaatata tctattagtt cttctttttt cataactgct cttcctttaa cttgttaatc
      121 taacttgctt acaaatatat cctaccacat ttgtgtacta tctgtcaata tttttttgtg
      181 tataaatgtg tattataaaa caaataattt tacacaaaca aaaaagagcc taactgctct
      241 tagcaataag ctctcatcac tgctcctcgt gaatttagtc agtacaatgt atttgccttt
      301 tctttgataa aatccttata cgaaaaattg ttcaaccaaa attgttttag cactaccgaa
      361 tttttgtttc catcattcaa ctccaattga ccaaatctgc tgatcatatc atcaatttca
      421 tcaattatct cttgtgccat catgccgtct tctagacgtt ctaatacgta caattcaaaa
      481 acatcccttt tcattcaaaa tgcccctttc aggttacctt ttgccatttt atgggctaac
      541 tccgcctact cagctttttt tatataccta ctgatatttg ctttcgtatt tcttggcata
      601 ccacctgctt gcaggtaatg ttcacgataa taagcatcta gctctgaaac agctttttct
      661 aatctattcg ttgcattcaa cactgagcgg tattcacgtt tttcccttaa tacacgtctt
      721 aaatggttca tcgctgatat ataaggctta tagtattcca atacagtata tcctctagaa
      781 atataggcaa ttggatttct agcttcatgg atcaattcta aaatatctgt tggatcaggc
      841 ttatccggca tctcttcttc gatttccata atactgatca agtagtccaa tccggaatca
      901 tcgactccat aactttcaca ccattctttt aggttgttca agtcatgaat aacatcttca
      961 ggatcaaact ctctaaaagc agtgatccct tggctataat attttatata ttccattgcc
     1021 gattcaaaat cctctggcgg tatgaaagct tcaatttctt cttcatcaat cgctttcagc
     1081 actattccga tacctgagtt tgaaggatat tttctcaatc cttcttcaat taaatcctca
     1141 tctattcgtc ctttttgaaa catcaccaat aattgttcta acagctgatc taaaaccctg
     1201 cgctcttcat tcagttccat tgcattttta acttcttttt caccgagttc aaagtaagct
     1261 ttgatcaact tttcttgttc ttttcgttca actaatttct tcttcaagtc attcatattg
     1321 agaatgaaat ccatgtgatt actcttttgc tgattgacaa aatcatatct ttgttccaaa
     1381 acatcccgat atttttttag ttcttcttga attatttcaa agctatcaag tacatgaaga
     1441 attttttcat tattattcat cagcccatct cctgtagtct cacgtttgtt ttcgactttt
     1501 caaaagtatt gtatttaaaa gcaattaacc ctacaaccct gctatctttg atgcctattt
     1561 ccttgttaaa aattccgtcc aatgttcctt tgactaaatt atcaatatcc ggctgtgaag
     1621 tacgcatcag tgaatcaagc tttttcttat cttttctcac ttggtaaaaa taatctatct
     1681 gagctataac ccccatagga gcattcatta cctttttcag ttgatcattt accaaatctt
     1741 tctctttaag cgtattcttg atattttcca aatagtcgtt gtactctttt ggatagtaag
     1801 tgataatccc atttcctcta aatttagact ttggtcttgg cgttgctact ggtttaaaat
     1861 caaatgtagc ttcccatata tctccgttca atccttcaga agtatcccac tcaaattctg
     1921 aatatcgttt gatcctcaca actgtttttc cttcgttcgc cacattatat ttaaaagcaa
     1981 ttaagcctgt gatatggcta tctcgtatag ctgagatgtt aaaaatacca tccatagcac
     2041 tttttactaa attatctaaa tctggcgctg ttgtcttcat aatgttatag acttttttat
     2101 agctttttgg tatctggtag taaaagtcca cttccataat tgcgcccata ggatcattta
     2161 caatcgagta aaattcatca tctaataaat cttgatcttc gataaagctc tttatttttt
     2221 tcaaataatc aagatacttt ttatcatagt aggttgaaat ccttttctct gctacgtcat
     2281 tagtttcatc agcagcattc cttcttgcac ttggtcttgg tgcagataca ggttggaacg
     2341 gtaaagttac agtccacatt agtctttttt gatctctttc aaatagattt ttttaaaggt
     2401 atcaaggctt aaaggagcta ccttttgcat cttccggatt ttatttactt gttccaattg
     2461 tttcaataga ccatcttctt ttctaaggta ctcaggattt gttatttgtt tattccgata
     2521 ctcgattaat gattgaagct ctcttactgt taaaacatcc tcaatttttg cttctttact
     2581 cgttatcttt tttagatacc ctaatactgt tggataagat ttgccgatca cttctgcgat
     2641 ttctttttta ttgtactcac caaattttcc aagcaaccag tcattcatga tcttacttga
     2701 tacttttggg tatacaagaa ttgctttttc aatggaatga ctgccattat ttctgatcag
     2761 ttgactatct ttacactcaa ctgtaacgcc atcacctaaa tcaacaacat attgccaaac
     2821 gcctcttcga ttcttattaa gagaaataat cgttccctct ttatctctat aatcctttga
     2881 taattcactt actgttgtaa ctctttcccc aatgctaaaa tgtctaatat cattattgtt
     2941 ttccacttat tatccctcca atattgctgg ttatctcttc ctctgacaag gaactatata
     3001 tcatataaag aattttaaca ttattcggaa tgagtgtaaa gaaactttat ataaaaagag
     3061 tgatttagtc taagaccaaa tcactctttc ttttttatta attatattgt tatctgatag
     3121 acctattagt aaatgcacgt cttattgttt gatcattctc gatcaattct tctaacaact
     3181 ctgaaactgt tactttctta cctcttgctc tttcttcttc tttagctcgc ttttctaaat
     3241 atttaacaga agctattttt aaagtcacat actttctaac tttttcttta tttactacca
     3301 tcagctatca tctccaaggt gtcacaccta tatattattg gtgtgacacc atttgtttat
     3361 tataactttc tggctattta gccaatttaa tcgttaatgc ttcgtttgct gtagaatctc
     3421 caaaaacttt accgtcttca taaactacat gaactggcaa atctgcaccg tctgaatctg
     3481 gtttagcagt accacgatac aaaccaatta ctctttttcc tagttctctt gcaaccgtaa
     3541 cttttttatc ctgatccata gattcaactg aattgaataa ggtaacatta atcatttgct
     3601 tttcagtatc caatttaaca gttttgatag ctttgaagac ttcagtgtta aaccgatcag
     3661 ccatagaacc agaaacagat tcaaacgatt tgactttttc aggatcaaaa tcaattttat
     3721 ctggtagttc cgcttcgaca gtagaacttg attcagttgt actttcttct gtagctactt
     3781 cttttttcgc tgattcgata atctttttcg ttgatgtttt atttattttt acatctttat
     3841 agtattcttc tccatcaacg ttaaaaacca atgtcagctt gtgtacaggg ctattctctt
     3901 taactgtata aaacacttca aattgtgatt gagacggctt aatagtagcg agaacgtcgt
     3961 ctgatgcttt cttgccatct tccttcactg tcagcgaaac atttttataa ctcgttacat
     4021 tttcaaatgt tccatctatt actacccttc ccaaagaatc tggagcataa ctattattaa
     4081 ctcccgatat accaaattgt ttatcgttac ttccaaaaat cttagtggca ttaaacacaa
     4141 taaaggttac aatcacaatt ccaatgccta tgttacgcat aatcggatta tttgtttgaa
     4201 attgaccaat aattatagcg attgccccaa aaaaagcaag aattaaacat aaataaccta
     4261 acagggttaa tagcatgatt catcacaact ttctattctt tatttttctt tttggttttc
     4321 gtttgttcaa actcatgctc atttagataa gtaatcaata aatctcgcat ggatttgcta
     4381 tccttactta gcgtatcaaa cgcttcttgt aagtcagcat ccttctctac agcattaaac
     4441 caatgcttcg ttccaaattc aaaaagatta ctaatcactc ttaacggttc ttgatcagta
     4501 ttcgtattaa gccattcaag tatccgttgt tgagctaatc ctaatttact ttcgtcttcg
     4561 tgatttgtac gtgcttcata gattttagtg tgtatatcat caaaatagtg gattcgttct
     4621 cttagcgctt cacgttgttc gtacatagcc cttttatttc taacttcttc gtctattgtt
     4681 tcaatctttt ttcttaacag tatttgaagt gataacattt ctgagacaga caaaaacact
     4741 ggaattttct tttcttttct ttttggcatt tttagcactc ccttttaatt cttttgtttg
     4801 atcaatgaaa cgttctttag aataaatccc aagatcattc cacagacaaa tccgattaca
     4861 tgtgacaaga catttgcctc gcctgattca aaagtagata ccaataaaat gccgattatc
     4921 aataatacaa aaacacttag taataaatgt ttcttgctat caaaacggat gtatgcaatc
     4981 gcaaataaag caatccatcc aaaaatacct ccactaagcc ccatacttac gatgttgctg
     5041 tgtagcagaa aaggaactaa gcttcctaga aatcctgata tgattaaaac gatcaataat
     5101 gttaaccact catactgatc attcagtgct tcttcaagaa ctactaagaa caataaatta
     5161 gaaattaaat ggtacaagtt aatatgagaa acgatagaaa tgaatatatt cgggaacaag
     5221 tgtccttcat acaaaccacc taaagcaacc atttcctttg cactcaatgt atttccaatt
     5281 atgctttttc caatctgcaa aaaatcaaac aggaaaatca atacacaaac aaaaactaca
     5341 gtcgctacta ggtatcgact actatttttg tttttttctc tcattcgcta cttcctttgc
     5401 tttagtaact gccgattctc catattctct aaaaagagtc gatgttagct ttcctctcgg
     5461 aatattgtat ttttttaaaa tttcagttgt tgaaagattt ttttcaaagt cttcaataat
     5521 ttgtttatga agatttattt tagccaaatc attggttgtc aaaacaggtt ctttagcttg
     5581 aatatcgcct tgacgaatta acctttgaat tttatttttg ctttttaaaa aaggatattt
     5641 ttcaattaaa gggtcaattg cattcccttc atcaatccac ttacctattt cttgataaac
     5701 tctcttttga aattttttcc tcagctcaat cgggttcgga aaaacattgt gcttaaaatc
     5761 gtgtgatact aggctctttg atttgcctaa ttcatcagcg acttcttgca ttgtaatttt
     5821 gttttcgata tagcattgga caagagcatt atatttttta gggttattat tatttattgt
     5881 catgttctta cctacgttca ttgctaattt tttggtattt ttctgtttgt gtattgcgat
     5941 ttttaaaagg catttcctaa tacgttaaat tttgataatc ggttcaattt tactgcttta
     6001 tcaatttctg cctgtgacca aggttctatt aaacgcattt ggtacgtcac tagcagatcg
     6061 acatgttcat attcaaactt ttctattccg taaatctgat aaaatatttt ttcttcgttg
     6121 ttactataag gaatcactgt tccgatctta aatatgtttc gtgtgttgtt tacaccaatt
     6181 tcatcagtaa tcttgtgtct atattctaat aacacgtatt tcttatacct gcttgtcaga
     6241 tcaggtgaat agttaacaga ttgacaaacc aagtcactgg ttatacgtgg atcacctatt
     6301 ctgttaattc tcgtgttata gattccgata ataatatagt ttttatcttt atattctata
     6361 gtttctccca cttctaactt ttgattaaag cctgttctat ttgcttcaaa aagttctagc
     6421 aatctttttc acctctactg ctactgccaa acaaatttag ctttatcatg ccatgtttca
     6481 gacattactt ttttaccatt ttcgtcaaat atcaccgctt cccactttgc tgttccatcc
     6541 ggctgtttac aaatatctgc aaaccatagg atcgtttttc gatcgttgaa tttccttact
     6601 ttcttctcaa atttattgat ctgaactcta ttttgattgc tgttccaacc tactaatagg
     6661 cggttatctg attctgtacc atgaaaacca atgggaacga tgtgggttct atcaaatgct
     6721 tcttttcctt ctggatagag cattggtcta agtttcctac gtttcaagtc atctcttgct
     6781 tgataccgcc atgccgattt tggattgaat ttaatagcta tttgatgctt gcttttgtca
     6841 tggtaaaaat atgcgacatc ggcttcagct ccaagcaact tttctcttgc actatttgat
     6901 tcaaacggtt tattcacttc taaaaccttc acccctaaaa tgccatgatc aagcatctgt
     6961 ttaggagtta gtaccgcttt tttatctctt ttcttcgctc gtttcacaac tacttcatct
     7021 gtatatttat atggagtaag ccatcttaaa aaagaactga cgatgatcat ttatgcacct
     7081 gtttttttgc ttttaacatt ttttgcatga taggtgaagt acttccattt atttgtttct
     7141 tttcagattt atcagttgtg atcactacgt tttctgagcc ttttggatca ttagctttag
     7201 gtttggtttt agatgcaatc ggctgtttat tattcgtgtt gtttgaggtt tgcggttcag
     7261 gatcagcttt tcctaatgcc cttaaaactt tttctagttt ttctgcttgc agtttttcta
     7321 gtgttttagc tccctgctcg actttttctt ctttgttctt ttcaagctta atagcaaacg
     7381 cactcttctt ttcaattgat ggctctttag atgatggatt tgctaaaggt gtgttcaaat
     7441 ttcttttagc agattttctt acaggagctt taccaattcc accaaaatcc tcgtcttcac
     7501 cgccctcacc acgagtttca gctacgattg ctcggtaatc aacatattct ggttctggca
     7561 tagtatttct aaggtgattg aagattgttt caatttcttt gttactgatg taagctccct
     7621 gcgctctaac catacttcca tcaacaagct taataagcat atctcccttt ggacttagac
     7681 tttctccacc gccttcatct aatacaatcc tactttctaa atcacttgct accataaggc
     7741 aaacacgtga cggaaaattg gctttgataa taccagtgac aactgttgat cgaggagatt
     7801 gtgttgctaa gataacatga atacctgctg cccttgccat ttgtcctaat tgaacaatca
     7861 aaccttctac ttctttatgt gttccaacca actgtgaata ttcatcaact aataagatca
     7921 catagggaaa tctatctaat ccattttttt cggcatattc gttatatagc gtgatgtttt
     7981 gtaaccctgc tttttccatc agtttgtaac gttcatgcat caagatcaca agatattcaa
     8041 aaaaatcata agcttcatcc atatctgtaa ttggatcagc caacatgaac ggcaattttt
     8101 tgtatcttcc aaattcaacc ctttttgggt ctacaattcc tatttttaat tcatcaggcg
     8161 ttgagtgaca cattactgta acaagaattt cattcagtaa tactgatttc cctgatcctg
     8221 tcgttcctgc aaccaacatg tgtggcattt cgctgatgca aaaatgagca attgtgccat
     8281 caggcttaat tccaaaaata gcatctgttg ggtctttagc ctttgtgttc aacatattga
     8341 cactgaattt tccattaagc tttatattag gttctttatc tagcaaaata gattcagctt
     8401 tttcggctct ctttttgact ttctctaata atttcatagc catttctatt cctcactttt
     8461 ctcggtactt ttctgtttgt gaactggtag tttgtatttt ctgtttctat ttgtgatgtc
     8521 ttctaaaaca cgctattgat cattgatggt acatcaattg gaatacgatc attttctcct
     8581 aatggtaaag taatttgaat acgccctgcg ttgatccgca cgattacacc tgatatatgc
     8641 aagtaagttt caatttcttc tttcattgag cttagttgaa tttttctggt acgagataaa
     8701 gtaaacaaat attcaataga tgtattccca acgtgcatat ctgttagact tgcaggtacg
     8761 tcagcagaag atagataaag ttctaaagat tgcttttgag tttcggcata ttttctagct
     8821 ttttcggttt ggttttggat atttttggaa ttatcggcaa agagattgat tggaaaagaa
     8881 aattgtgaat ttgaaactgc gattgaagat gttgctcttt ccgtttcttt gtttttggta
     8941 cttactcttt ccttacgttc tctttcaata tttactgatg ctcggaaaat gaaataatcg
     9001 cctgaaactt catcttcttt ttcaccaaat ttggctcgtc cgcttgttgc tcttgtcagg
     9061 atcgacccta aatcttgaat ttgtcgtaaa actgtttctc taactttctt cccttttggt
     9121 tgcgggattt ttacgatata ttctcgaata tcttcattga cacttagatc acgtcttgta
     9181 tgaacagaaa ttttgatatt tttaagcgtt gatagcacat cggattctaa ttgcgttttg
     9241 tttcgttttc tttttttgtt gttcgtttca tctcctataa tcttgtttgg atcatacttc
     9301 acatccatag cttctagagc ttctcttttc aaccttctac tttccatatc atcaaaaaat
     9361 ggtctttgtt ctccatagtg atgcctgaac atcaaagtaa ccaaatatcc aacaaagaat
     9421 accgttcctg cttctaatac taaaatagag atgtctacca agtgtagctt tgcaaaaaag
     9481 ctttgtacat tatatgaata acttaaataa ttgggaaaaa acgcattgag taactcttta
     9541 aacatctctt ttaatcctaa atcatctgtt ccgttaacat catttaacga gacaagaata
     9601 cttactaagg tatctacaag cagttgtaca acctttgtta cccaatgcaa aatatatatg
     9661 ccaattgcac caactaccaa tgcacgtcca accagatata ctgatttaga aaaactggct
     9721 acaggataat atttttctcc atcgcttcgc ttatattcct ttaattcaat ggatttttcg
     9781 ctcatctgaa tatctcctta ttttctttct gattttggtt catcgtcact tatgctgtcc
     9841 tcacacatct gcgtatcttt aggaatgatt actctgattt cgtctaacat ttctctctca
     9901 atgatcatcg ccccttttgt actaacagtt ttctctgata attcaacaca tttccctatt
     9961 tcagaatctg gatcaaaaat agcctgttct acgtcaaaat gattcttagc tacatacacg
    10021 atactcattg tttctaactc tctagcaact gaatatttac ccttcttcag aagatagtag
    10081 ccatttcctt tttttattcg atttgcaact gatttatcta atccattgat gcttattgtt
    10141 tccaattctt caccttctca atttctaatc tcttacccaa gtaccatttt gatagttgat
    10201 gttgattcct ttttgattgt taaatacata aacattaagg tttaccgttt ttccattatc
    10261 gttaactgag aaagcttcga catgagaacc acgaggaact aattcattcc ctttataaat
    10321 tggatcaact ttatacaata ctttttcatt cttattttta tagattgcat cacgtacaat
    10381 cgtttctgag taagccatcc ctccattctg atcatttttc ccaacatttt gcgctctcgt
    10441 tccaagtgtt aaattgtgta cctccatatc tcctcctagc gaccatgcta atgaatgact
    10501 tttgttatag agataacctt tatagccttc tagctgagtg atttcattgt ttgaatcttt
    10561 gccgacccaa gtatctctct cttgatcaaa tactccatcc ttgtattctc ctgcaatatg
    10621 gacagaactt ttgaaagatg gacgttccac atttttagat gagtgagaat ttacagcatc
    10681 ataggtgatc aacgcttcaa catctcctgc tcttccaagt tgatctaaat ctgcataatt
    10741 tacccaaaag gtttgactgc ctttttctga taatgcttca tggtcttctt ttgtcagtgt
    10801 atatttccca tcattaatgt ttacgatatt atttggatat ttgtttggat cataacgtat
    10861 ccctaaaaat tcttttgatt cactgtctgc tttattacct acctgaacac tacttttgat
    10921 ctgaaaatca tgttcctgag tactgttatt ctgaaagtaa cccttgccac taagaccaac
    10981 cgcaactaaa accaaaattc ctaacaacga tcggctaaac ttcttctttt tcataccacc
    11041 attcctttta ttgtgttatc ataataagat aaatatataa taaactatat tgtaaatttt
    11101 gtcaaatgta tttttattta ttcccactat aaaccttgat atatagccaa tttaaaaaag
    11161 gatggcaaaa aattatcaag ttaaaaaaat aaattttgaa ccaaattatt tttaataaaa
    11221 tagctagttt ttttatcaaa aaaaatagag cttttcagct ctattcagac tgtagacaaa
    11281 ctcctaaatt tggagtgttg tttgcagttt tttgttttat actaattgta taaactattc
    11341 tgggagtgat tctaatgatg agaaaacaat cgattgaagg tagaaatcaa tttgctatgt
    11401 taacaattga tgatcttgta cctaaagatc acttagttcg aaaaattgat gctgcgattc
    11461 agtttgattt catttatccc attgtagaat ctacgtattc aacctatggt cgtcccagta
    11521 ttgatccagt ggtcttaatt aaattagtat ttatccaata tttatttggt atccgttcga
    11581 tgagacagac aattaaagac gttgaaacaa atgttgctta ccgttggttt ttaggttatt
    11641 cattcgagga tcctatccca cacttctcta cttttggtaa aaactatgtt cgaagattta
    11701 gagaaacaac tttatttgaa gatattttct ctcatattct agaacaagct gtaaaagctg
    11761 gcttcgttac ggaagacaac ctttatattg attctactca tatcaaagca aatgccaata
    11821 aacataagtt cacgaaagag atgacctacg gtcaagcaaa agcttatcaa gatgaattag
    11881 aagatgaaat aaataaagaa cgtattgctg taggaaaacg tccttttaca tgggacacag
    11941 aaagtgagtt gagtcttcaa aaaataagtc attcagatcc agaaagtggt tactatgtta
    12001 aaggtgaacg agaaaaacaa tttgcttatt ctgcacatac ttcctgtgaa gataacggtt
    12061 ttatcttatc tacattaatc acaccaggaa atgtgcatga cagccaagtc gcaatcgatc
    12121 tggttaaaca gtcgaaaaga gcttttccaa atataaagcg tgtggttgct gatgcaggat
    12181 ataagacgcc taaatttgtt cattttctgt cacacttgaa actctacccg attcttccat
    12241 atactgcacc tcatggagtg aaaggaatgt ttcgtaaaaa agactttgtt tatgatgcct
    12301 attttgactg ctatttatgt cccaataatc aaccgttgtt attttcaact atcactcgtg
    12361 atggttatcg aacctataaa tcaaatccaa aattctgtgt gagttgtcca ttacttgaaa
    12421 attgtacttt gagtacaaaa catcaaaaaa tagtgactcg acatatttgg gctgatctta
    12481 tggatgaact tgaacaccaa cgccatacgg cgttgaatag agaaatttac aaaaagagaa
    12541 aacaaaccat tgaacgaata tttgcagatg caaaagaaaa gcatggtatg cgttggacga
    12601 aatatcgagg tcttgaaaaa gtcgccacgc acacgatgct tacgtttgct gccatgaatt
    12661 taaaaaaact agccacatgg ctatggaaaa caaaaaagcc tatggctttt tatttcaaaa
    12721 ttatgcaaag actaacaaaa aggagtggct taattaccaa ctcctttttg tctacaatct
    12781 gaatagagct tttcagctct attcaatatc attttgatca attaataatc gtacactcca
    12841 attaaccgag ttttgatcac tcaaatattt ataatctttg tcatcaaaaa ccagttgcca
    12901 aactctggta cgaacagttt cttcgtccac ttcctcatct gaagagtatt gcgataatgc
    12961 ttcttcaact atatacttta caacttcctc aaaatcagta ggaactttat caataaccac
    13021 ttcatagtct tcttgtttta cgatattggg atcaatatgt tcatccaaac atacctcagt
    13081 gagtttttct ttcacttctg tatctctttc tgtttttagg tactctgcat agtcttcctt
    13141 agaccattgt ttttcaagat catccgctat acttttaata aaggattctt tatttaacca
    13201 attatctgcg gtatctatac cttcaaactc aaaagctgtt ccttctatac gtgatttgac
    13261 gaaagcgtca attttcttgt attgattatt catttcccat gaaacacact catcttcttg
    13321 cgtaatatca taaatttttt cggaaaaact aactaattca ttccacgatt tatcctcggc
    13381 aacttgactt agtttcgatg caataaaagg aaattttgct tttaagtcat ccatattctt
    13441 gatctcaaat tcgatatttt cttctcctac agctgaaatc catgctgaaa gattgattgc
    13501 aatatcgcta aagtcttcta cattttcgac atttcctgta ttatctttta ttactgcttc
    13561 taaagccata tcggttgttg cactcatggt ttgatctcct ctcataatag agcaaaaagc
    13621 cggtttaacc gactttttgc atggtacgtt ttgtttggta gttttctgct tgtgtttatg
    13681 ttgaaataat ccctatagct cttctt
//
LOCUS       DAFLWQ010000076        13652 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.079, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000076 DAFLWQ010000000
VERSION     DAFLWQ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.079"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            28..270
                     /gene="yaaA"
                     /locus_tag="L1V16_002229"
     CDS             28..270
                     /gene="yaaA"
                     /locus_tag="L1V16_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBN1276552.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            257..1381
                     /gene="recF"
                     /locus_tag="L1V16_002230"
     CDS             257..1381
                     /gene="recF"
                     /locus_tag="L1V16_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBN1276553.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDSRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            1378..3324
                     /gene="gyrB"
                     /locus_tag="L1V16_002231"
     CDS             1378..3324
                     /gene="gyrB"
                     /locus_tag="L1V16_002231"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBN1276554.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            3344..5815
                     /gene="gyrA"
                     /locus_tag="L1V16_002232"
     CDS             3344..5815
                     /gene="gyrA"
                     /locus_tag="L1V16_002232"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBN1276555.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            6051..6350
                     /locus_tag="L1V16_002233"
     CDS             6051..6350
                     /locus_tag="L1V16_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBN1276556.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            6400..6912
                     /gene="ssb"
                     /locus_tag="L1V16_002234"
     CDS             6400..6912
                     /gene="ssb"
                     /locus_tag="L1V16_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBN1276557.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            6938..7174
                     /locus_tag="L1V16_002235"
     CDS             6938..7174
                     /locus_tag="L1V16_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBN1276558.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            7317..9290
                     /locus_tag="L1V16_002236"
     CDS             7317..9290
                     /locus_tag="L1V16_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBN1276559.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            9296..9748
                     /gene="rplI"
                     /locus_tag="L1V16_002237"
     CDS             9296..9748
                     /gene="rplI"
                     /locus_tag="L1V16_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBN1276560.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            10022..11389
                     /gene="dnaB"
                     /locus_tag="L1V16_002238"
     CDS             10022..11389
                     /gene="dnaB"
                     /locus_tag="L1V16_002238"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBN1276561.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            12169..13461
                     /locus_tag="L1V16_002239"
     CDS             12169..13461
                     /locus_tag="L1V16_002239"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBN1276562.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT         4542 a         2471 c         3009 g         3630 t
ORIGIN      
        1 tttaataatg aaaatgaggg atgggcattg aaacaacaag tcattctaaa tacggaattc
       61 atgacgttgg gccaaatgtt gaaagaagtc acagttatcg gtagtggcgg acaagcaaaa
      121 tggtatttgg cagaaaacac tgtgttagtc gatggcgaac cagaaaatcg tcgtggacgc
      181 aaactttatc ccggcatgat ggttgaagtt ccagaagtag gaactttttt tatggtaaaa
      241 aaaggaaacg acgataatga ggctgaataa gctgtattta aaaaattatc gaaattacga
      301 agagctgaac atcgaatttt ccaagaacct cgtcatcttt ttaggagaaa atgcgcaagg
      361 aaaaacgaat cttttggaaa gtatctacgt attagctatg acgcgaagtc atcggacaag
      421 tagtgagcag gaattgattg gctggactga cgatcaggcg atgattcaag gagagatcac
      481 aaaaggttca tccactcttc cattagaaat cttattatct aaaaaaggcc gaaaaaccaa
      541 gatcaaccat atcgaacaaa aaaagttaag tacttacgtg ggacaaatga atgtcatttt
      601 atttgcacca gaagatcttt ctttagtaaa aggcagcccg cagatcaggc ggaagttttt
      661 agatatggaa ttaggccaga tcaatccaat ctatctttat gatcttgtcc aataccaagc
      721 aattttgaaa caaagaaacc agtatttaaa gcaattgaat gaaaaaaaac aaactgattt
      781 gctttatttg gatattttgt ccgaacaact agcagcgttt ggcagcaaag tattgaaagc
      841 aagagcacag ttcgtcaagc gattggagtt ttgggctaat tctttgcatc agcaaatcac
      901 ccatcaaaaa gagcagctgg aaatcgagta tctcaccgca gtcgattctt tagaaacaca
      961 tacgcaagag caaatccaag aacaatttct cgcacttttg aaccaaaata aaaagaaaga
     1021 cctttttcgg ggaacaacga cagttggtcc tcatcgtgac gatctttcct tttttattaa
     1081 tcagaaaaat gtgcagactt atggatcgca aggacagcaa agaacaactg cactaagtgt
     1141 caaattagca gaaatcgatt tgattaaaga agagacgggg gaatatccaa tccttttgtt
     1201 agatgatgtg atgagcgagc tggatgatag tcgtcaactc catctgctag aaacaatcga
     1261 aggaaaagtt caaacgttct taacaacaac gacacttgac catgtaaaaa ataaaatgac
     1321 tgttgaacct gagatttttt atgttcaaca agggaaacta aaaggagaag aaactgaatg
     1381 acagaagaaa gaagtttagt agaacgcgct aaagagtatg atgccagtca gattcaagta
     1441 cttgaaggac ttgaagccgt tcgtaaacga cctggcatgt atatcggttc gactagttct
     1501 gagggtctgc atcaccttgt ttgggaaatt gtcgataatt cgatcgatga agtattagca
     1561 ggttttgcaa cgaaaatcca tgtgattatt gaaaaagaca acagtatcac cgttattgac
     1621 gacggtcggg ggatacctgt agatatccag gcaaaaactg gacgtcctgc agttgaaacg
     1681 gtctttactg ttttacatgc tggaggaaaa ttcggcggtg gtgggtacaa agtttctggt
     1741 ggacttcacg gagtaggatc ttctgttgtt aacgcgcttt ctacacagct tgatgtcaaa
     1801 gtatacaaag aaggaaatgt gtactatcaa gaatatcgtc gtggagctgt agtggacgac
     1861 ttaaagatta tcgaacaaac ggatcgccat ggaacaacgg ttcactttac gccagaccct
     1921 gaaattttta cagagacaac tgagtttgat ttttcaaaat tggctacccg gatccgtgaa
     1981 cttgctttct tgaaccgcgg gatgcgtata tcgattgaag acaaacgaga agaagaacca
     2041 gtcatcaatg aataccatta tgacggcggg attaaaagtt atgtcgaata cttgaatgca
     2101 aacaaaaccg tgatttttcc agaacctgta tatttggaag gtgaacagca agatatcgca
     2161 gttgaagtct ctatgcaata tacagacggc taccattcca atatcatgag ttttgccaac
     2221 aatatccata cgtatgaagg cggaacacat gaatcaggat tcaagactgc tttaactcgt
     2281 gtgataaatg attatgcccg aaaacaaaag ctgatgaaag aaaatgacga caacttgacc
     2341 ggtgaagacg tgcgagaagg attgacagct gttatttcta tcaagcatcc tgaccctcaa
     2401 ttcgaaggac aaacaaaaac aaaattgggc aattccgaag tacggacagt cactgatcgg
     2461 ttatttagcg aacatttcat gaaattcttg ctggaaaacc caagtgtggg ccgtcaaatt
     2521 gttgaaaaag gattactagc ttccagagct cgtctagcag cgaaacgtgc gcgtgaagta
     2581 acgagacgta aaggtgcttt agagattagt aatctgccag gaaaattagc ggactgctct
     2641 agcaacgatc ctgaaaaatg cgaattgttc atcgtcgaag gagattcggc cggcggatca
     2701 gctaagcaag gtcgtaatcg agagtttcaa gccatcttgc ctattcgtgg gaaaatcttg
     2761 aatgttgaaa aagcaagcat ggacaagatc ttggcaaatg aagagatccg gtctttattt
     2821 actgctatgg gtacagggtt tggagaagat tttgatgtat cgaaagctcg ctaccacaaa
     2881 ttagttatca tgactgatgc cgatgtcgac ggcgcgcata tccgtacatt gctgctgact
     2941 cttttttatc gttacatgcg tcctattgtt gaagctggat acgtctatat tgctcagcca
     3001 cctttatacg gggtaaaaca agggaagaat attacgtatg tacaaccagg aaaaaatgca
     3061 gaagaagagt tgaaacaagt cgttgcttca cttcctgcct caccaaaacc aagcgttcag
     3121 cgttataaag gacttggaga aatggatgat catcaactat gggaaacaac tatggaccca
     3181 agcaatcgga tgatggcccg cgtcagtgtg gacgatgcta ttgcagcaga tcagatattt
     3241 gaaatgttga tgggggatcg agtagaaccc cgtcgtgcat tcatcgagga aaatgcacac
     3301 tatgtgaaga acttagatat ttaatcatga aggaggaaaa agaatgagtg aagaaatcag
     3361 agaaaacatc catgatgtca atctaaccag cgaaatgaaa gactccttca tcgattatgc
     3421 gatgagtgtt attgtcgcac gtgcacttcc tgatgtcaga gatggtctga aacccgttca
     3481 tcgccgtatt ttatacggca tgaacgaatt aggtgtaaca ccggataaag cccataaaaa
     3541 atctgccaga atcgtcggag atgtcatggg taaataccat cctcatggag actatgcgat
     3601 ctatgagtca atggtacgga tggcacagcc attcagctac cgttatatgc tagtggatgg
     3661 tcatggaaac tttggttctg ttgacggtga cggtgccgcc gctatgcgtt ataccgaagc
     3721 acggatgagc aaaatcgcta cagaaatgct gcgtgatatc aataagaaca ctgttgattt
     3781 ccaaagcaac tatgatgata cagaaaaaga accagttgta ctacctgctc gcttcccgaa
     3841 tcttttagtg aacggaacaa cggggatcgc cgtaggtatg gccacgaata tcccacctca
     3901 taacttgtct gaggtagtag cggctatcga tttgctgatg gataatcctg atgtgacgac
     3961 caatgaattg atggaagtat tacctggacc agattttcca acaggtggtt tggttatggg
     4021 aaaatcagga atccgaagag cgtatgaaac aggtaagggt tctattaccg tacgtgcaaa
     4081 agttgagatt actgagatgc caaatggtaa agaacggatc atcgtgacag aattgcctta
     4141 tatggtcaat aaagcaaaat tgatcgaacg gatttctgaa ctgcacagag acaagcgtat
     4201 cgaagggatc acagatttgc gggacgaatc ttcccgtgaa ggtatgcgga tcgtcattga
     4261 catccgtcgt gacgccagcg catctgttat cttgaataac ttatataaat tgacatcctt
     4321 gcaaaattca tttggattca atatgttggc gatcgaaaaa ggtgtgccga aagttttgag
     4381 cttgaaacaa attcttgaaa actatatcga acatcagcgc gaagtcatca caagacggac
     4441 agtctttgaa aaagaaaaag cagaagcaag ggcacacatt ttagaaggtt tgcgtattgc
     4501 tttggatcat atcgatgaaa tcattgcgat tatccgcggg tctaaatcag atgacgaagc
     4561 aaaagcgacg atgatcgaac ggttcgattt atccgatcgc cagtctcaag ctattttaga
     4621 tatgcgttta cgccgattga ccggtttgga acgggaaaaa atcgaaaatg aataccaaga
     4681 actcttaaaa ctgattgaag atttaactga cattctggca agaccagaac gtgttacaga
     4741 aatcatcaag aatgaattag cagacttgaa tcaacgattt ggtgataaac gacgcacaga
     4801 attactagtc ggtgaggtct taagtctgga agatgaagat ttaatcgaag aagaagaaat
     4861 cgttattaca ttgacaaaca atggttacat caaacgtttg gcaaataatg aattcagagc
     4921 tcaacgaagg ggtggacgtg gtgtccaagg aatgggtatc cacaatgacg acttcgtcaa
     4981 aaatctggtt tcttgttcta cccatgatac attgttattc tttacgaata acggaaaagt
     5041 gtatcgggca aaaggatacg aaattccaga atacgggcgc acagccaaag gaataccaat
     5101 tatcaattta ctaggtatcg attcgagtga aagcatccag gcaatcattg cggtgacggg
     5161 agaagcagaa gaaggccact atctcttctt tacgacgcgt caaggtacag taaaacgtac
     5221 ttctgtcact gcttttgcta acatccgaag taatggtctg atcgcaattg gtttgaaaga
     5281 agacgatgag ctcgtcaatg tgctactgac agatggtcaa tctaatatca ttattggaac
     5341 acataacggc tactctgtca ctttcaaaga agaagcagtc cgcgatatgg gacgtacagc
     5401 ttccggggtt agaggaatac gcctgcgtga ggaagattat gtcgttgggg cagccttaat
     5461 gaaggaagat caagaagtat tagtgatcac agaaaaaggt tacggaaaac ggacaaaagt
     5521 atcggaatat ccagtgaaag gccgcggagg taaagggatc aaaacggcga acatcactga
     5581 aaaaaatggt ccactagctg gattgaccac tgtttctgga gatgaagaca tcatgctgat
     5641 tacagataaa ggtgtcatta tccgtttcaa cgtatcgact gtttctcaaa ctggacgttc
     5701 aacattaggc gtacgtttga tgaagatgga agctgatacg aaagttgtca cgatggcagc
     5761 agtcgaacca gaagctgcag aacaaacagt tgaagaacaa ggatcagaag aatagccatc
     5821 aagactaatt gtgtaagcta gcaagaatga ccgattaaaa aatctggtta ttcctgctgg
     5881 cttttttgat tagttgaatt tctcttaaaa tattcgaaac tgttcattct gtattgcttt
     5941 tgaccaaaat agagtgtata atcagagctt gtgagtagtc taattaatta gataactctc
     6001 cttgctctta ggaacctaag agccgaaagt ccacagggag gtgaatatca atggaaaaca
     6061 cgaaatatga aatcatgtac attattcgtc caaacattga tgaagaagca aaaactgctt
     6121 taatcgaacg tttcgatgca atcttgaaag ataacggagc agaagttatc gaatcaaaag
     6181 attgggaaaa acgccgtttc gcttatgaaa tgaacggtta ccgtgaaggt atctatcaca
     6241 tcgttaaagt atcttctcca tcatcagcaa atgctgtcaa tgaatttgac cgtcttgcta
     6301 aaatcaacga cgatatcatt cgtcacatga ttgttaaaga agaagcttaa ttgttgtttc
     6361 atgtgaaaca atagaaaacg atgagaggag atgactattt tgattaataa tgttgtatta
     6421 gttggacgtc tgacgaaaga tccagatttg cgttacacag caagtggtac ggcagtcgca
     6481 acatttactt tggctgtgaa tcgtaatttt acaaaccaaa gcggcaatcg cgaggctgat
     6541 tttatcaact gtgtgatttg gcgcaaatca gcagaaactt tagcaaacta tgctcgtaaa
     6601 ggaacacttt taggtgttac tggacgtatc caaactcgtt cttatgataa tcagcaagga
     6661 caacgtgtat acgtgacaga agtagtagct gacaacttcc aattgctgga aagtcgttct
     6721 gcatctgaaa atcgccaaca aagcggcgga ttccaaagtt ctggtcaatc agctggcgga
     6781 tttggcggaa acaataactc taatcaaaca tctcaatcat ccaacggtat gcctgatttc
     6841 gaccgtgata cttctgaccc attcggctca agttcaacga tcgacatttc agacgatgat
     6901 ttaccattct aaacgaattt gataggaggg aaatagaatg gcacaacaaa gaagaggcgg
     6961 acgtaaacgt cgtaaagtag actacattgc tgctaaccat attgaatata tcgattataa
     7021 agatatcgaa ttactaaaaa gatttatttc agaacgcggt aaaatcttgc cacgtcgtgt
     7081 aactggtaca ggcgctaaaa accaacgtaa aattactgtt gcaatcaaac gcgctcgtat
     7141 catgggcttg ctacctttcg ttagcgaaga ctaataaatc ctaggaattg aatgactgat
     7201 ccttttgatc agctattcaa ttcctttttt tctgtaaaaa taacctctat tcgtttagtc
     7261 gctcgaatga cgaaagttat ggtaaaatca aattagtcat atatgggagg aaaattatgg
     7321 aaaataaaaa caatcattta tccccgaaac ctctcttcct tatcctgttt atattaatcg
     7381 aagtattggt agtcttaatt ttaccatttc gttttgttag cgcttcggtc attctattga
     7441 tgaatttatg gggtgttcgc tattggttga aaatgaaacg ttggcttatt ttaaataaac
     7501 gtgaaaaaat ccagcaggct tcgactgtag ctgaaaccaa tctagcttat gtctcagaag
     7561 tcatgcctgt aggagtgatt gcttatcagc catcaagcca aaaaatcgaa tggctcaatc
     7621 cattagcatt gaaaatcaaa gatcaaagtg gattaacaga ggaagaattg ctagatactt
     7681 tttttactgc aaaagaaaaa aagaaaaacc aagtctatct agcagataaa acatttcagt
     7741 ttgatatgga tacagtaaag ggtgttgttt attttaatga tattacccaa aaccagttgt
     7801 taaaactcca tcagacgaac agtcagccgg tgattggtat tttatctatt gataactatg
     7861 cagatgccat tgataaattg gatgacaaag agatttctta tttgaactct ttcgtcacta
     7921 cactagtttc tgactggatg aatgaatacc atgtcttttt caaaagaatc aacgcagaac
     7981 ggtttttctt cgtagcacag atgatcgatc tgaaaaagat gatggataaa aaatttgatt
     8041 tgctggatcg ctttcgagca gaagctgaaa aacagagctc gcctatcacc cttagtatgg
     8101 ggattgctta tggctcaaga accctcgatg aaatcggtgg agaagctcag aataatttag
     8161 atgttgcttt agtccgtgga ggcgaccaag ttgtcgtgaa agaggtaaaa gaaggagcaa
     8221 aacctgttta ttatgggggg aaatctgcta agaatgtcaa acgcacgcgt gttcgttctc
     8281 gagcgatgag taccgctttg cgtcggattt ttgatgaaac aggcgatgtg tttatcatgg
     8341 ggcacaagtt tccggatatg gatgctttag gctctgcttt tggtgtcagt tgtctggcac
     8401 gcttcaacca gaaaaaagct tacatcgtta tcaacgagaa cgagatcatt ccagatgtag
     8461 aacggtgtct tgaagaaatc cataagcatc ctgaattaga aatgcaacta atctctccag
     8521 aacgtgccat agagctgaaa aaagaagagg acctcctcgt gatggtggat taccataaac
     8581 cttctctatc gatctctcag ggcctatatg agcaatttga taagattgtg atcattgatc
     8641 accatcgtcg tggggaagag tttccaagta aacctctgct gacttatatc gaatcttcag
     8701 cttcttcagc ttcagagcta gtttctgagc tgatccaata ccaaagcagc aaaacaaatc
     8761 gcttagatcg ttttgaggcc acattattgc ttgcagggat ggttgtagat acaaatagtt
     8821 tcaatgtccg tacaactgca cgaacttttg acgttgccag ctatttaagg tcttgtggag
     8881 cagacgcatc cttagtacaa tatttattga gctcggattt agcgacatac ttggagatca
     8941 gcaatttgat tgctggaagc gactatgtga cttctgatat tgttgtggcg gcagggacag
     9001 acgaaaaaga gtataatagt gttatagcag caaaaacagc agatacattg ctttcgatga
     9061 tcaatatcaa tgcagctttc gtcattacaa agcggacaga cggcttgatt gggatcagtg
     9121 ccagaagtac cggcacgatc aacgtccaaa tcatcatgga atccttaggt ggcggaggac
     9181 acttcacaaa cgcagctact caactggaaa atacgacagt tgaggaaaca aaacagaagc
     9241 tatttgctgc aatcaaagaa aatatgaatc aaatatatga taaggagtaa tccaaatgaa
     9301 agtaattttt ttacaagatg taaaaggaaa aggtaaaaaa ggggacatca aagaagttcc
     9361 agcaggttat gcacaaaatt atctaatcaa aaataacttg gcaaaagaag caacgaaaag
     9421 cagtatcagt cagttagcag gacaaaagaa agcacaagaa aaacacgaag ctgaaatctt
     9481 ggaagaagct aaaaagttaa aagaattctt ggaaaaagaa gatactgtag tcgaattgaa
     9541 ggcgaaagca ggggaagaca gccgtttgtt tggttcgatc ccttcaaaac aaattgctga
     9601 agggttaaac aaacaataca aaatcaaatt agataaacga aaaatcgaat tagaaaatcc
     9661 gatccgttca ctaggctaca caaacgtacc tgttaagctt catcatgagg tgacggctac
     9721 gatcaaagtt catgtcgtac aagaataaca aatcttgata gcgatgttca gctggtaagt
     9781 ataaccagaa ggaaaaaaga caaaccgaaa tttatctgag aaaacagctg cagcaatgaa
     9841 agcaaaagct gcaaatcgat ttcagattga tttcggtttc ttttttggga acagcaaaat
     9901 agcataaaga aaacgagtat aataaaagag aactattttt ttattacact ttcggtacga
     9961 atgatgactt ttctctcatt ttcttgtaaa atgaagcaat tgaagacaag gagcgatacg
    10021 tatgaatgaa gtgtggcagg atcgaatccc accgcaaaat attgaagctg aacaagcggt
    10081 tttaggctct gtttttcttg acgcagaaac gatcattgat gccatggagt acatagagcc
    10141 aaaagacttt tatcgtcgtg gccatcaaat tatttttgag acaatgatcg agttaaatga
    10201 tcgtaatgaa gcgattgacg tggttactgt caaagaccgg ctggaacaag ccaatttgtt
    10261 agaagatgcc ggtggtttaa gttatctctc agacttggca ttagcagttc cgacagcagc
    10321 aaatatcgtc tactatgcga aaatcgttga agaaaaatca ttgctgcgta cattgatcca
    10381 gacagcaaca ggaatcgtta cgaaaggatt cgagcaagga gaagaagttc aaacaatttt
    10441 agatgatgcc gaacgcagta tcttggaggt ttcggaaaaa agaaatcgaa gcggcttttt
    10501 atctattgct gaagtactga actccacgat tgaaaatatc gatcgactag ctcaaaacaa
    10561 tgaagaaatc acaggtctac caactggcta tcaaggtctg gataaaatga cagcaggttt
    10621 ccagcccgaa gaactaatca ttcttgctgc acgtccagcg gtaggtaaaa cagcgtttgc
    10681 attgaatatt gctcaaaatg taggaacaaa aacagatcgt tctgttgcga tatttagttt
    10741 ggaaatgggg gcagaatctc ttgtaaatcg gatgctttgt gcagaaggtt cgattgaggc
    10801 cagccattta cgtacaggtc agctttcgga agaagaatgg tcgaatctga tcgttgcgat
    10861 ggggagtctt tctcgagcaa atatttttat cgatgataca ccagggatca aaatctctga
    10921 aatccgtgcg aaatgtcgga aactagcgca agaaaaaggc aatctaggct tgatattgat
    10981 cgattatttg cagttgattg aaggtaacgg taaagagaac cgtcaacaag aagtatcaga
    11041 tatctctcgc caactgaaaa aactggcgaa agagctgaaa gtacctgtca ttgctctttc
    11101 acagttatct cgtggagtag aacagcgaca agacaaacga ccagtgctaa gtgatattcg
    11161 tgaatccgga tcaattgaac aagatgcgga catcgtagcc ttcttgtatc gagatgatta
    11221 ttatgaaaga gaaggcggag atgacgatga tggaaacgag ccaaaaaatg acaacgtcat
    11281 cgaagtcatc atcgagaaga accgaagcgg tgcacgagga acagttgaac tactgtttat
    11341 caaagaatac aataagtttt cgtcgctttc gccaagagaa gaattttaaa gaagaggttg
    11401 tgagccttga gcaatcccga gagctctcgt aagaagatgc aaggagtaac cgcaggaacg
    11461 actagagtac ttaatttaaa cagatctcca aagggattgt gacaaaagtc ttgtcacagt
    11521 ccctttttcc gaataaacgg tgttcaatca gctgaccctt ggtattagct cagcaaacgt
    11581 caaaatatga ggaactattt tgacgtttgt ttctctaata ctcaggtcaa aacgctgatc
    11641 ttacgacctc ttttccttaa acggtgttct cctgccaact cctcggtcac aagtcacaat
    11701 atcatcaaac atgagaagca gttttttgaa attgctcctt gtgactcaga gttaaacggc
    11761 aggctcacaa cctctttctt aaacggtgtt caaaagcttg catctgcggt aatacgccca
    11821 atcaaacgaa aaatatgaga agctattttt gtttggctgt tcttattact tgatgcagga
    11881 cagctttttc acaacctctg attcacggtg ttccaaaagt agcttcttcg aaaaataagt
    11941 cgaaatttca caaaaatttg agaagcaatt ttcgtacatt ccttcttatt tcttgaagct
    12001 gaccacttct gttacaacct cttttttaat aaccattcta aaaagataaa gttcgttttt
    12061 taagcgtttt tataaaataa aaataaaaat cattcgattt tatttgaaat atgtatctat
    12121 tattgataca atggttcagg attaaataat atagaacgag gtgttcacat gtcatctgta
    12181 gtagtagtag gtacgcaatg gggcgatgaa gggaaaggaa aaatcacaga ctttctcagt
    12241 gaaaatgctg aagtgattgc acggtaccaa ggtggcgaca atgcagggca cacaattaag
    12301 tttaacggtg tgacttataa actgcatttg attccttctg ggatttttta taaagacaag
    12361 atcagtgtga tcggaaacgg cgttgtagtc aatcctaaat cattggttaa agaattagct
    12421 tatttacatg aaaaaggtgt agaaacaagt aatttgcgta tttctgaccg cgcgcacgta
    12481 atcttgcctt atcatatcaa attggaccaa ttacaagaag atgctaaggg cgaaaataag
    12541 attggtacaa cgattaaagg aatcggacct gcctatatgg ataaagcagc tcgtgtaggt
    12601 atccgtattg cagacttatt agataaagaa atttttgaag aacgtcttcg tttgaatcta
    12661 gatgacaaaa accgtcaatt tgtaaaaatg tttgattcag aaccacttga ttttgacgat
    12721 atttttgaag aatattatga atacggacaa caaatcaaac aatacgtcac agatacttcc
    12781 gttatcttga atgatgcttt ggatgcaggc aaacgcgtgt tgtttgaagg cgcacaaggt
    12841 gtaatgctgg atatcgacca gggaacttat ccttttgtta cttcttctaa cccagtagcc
    12901 ggtggggtaa caatcggaag cggtgtaggg ccttcaaaaa tcaataaagt tgtcggcgtc
    12961 tgcaaagcct atacgtcacg tgtcggtgat ggaccatttc caactgaatt atttgatgaa
    13021 acaggagaac aaatccgcga agtaggacga gaatacggta cgacaactgg tcgtccgcgt
    13081 cgtgtaggct ggtttgattc tgtagttatg cgccattcta aacgagtttc aggtattacc
    13141 aacctatctt taaactcgat cgatgtatta agtggattgg aaacagtaaa aatttgtacg
    13201 gcttatgaat tagatggcga actaatctac cactatccag caagcttgaa agagttgaac
    13261 cgctgcaaac caatctatga agaattgcca ggctggtcag aagacattac aggatgcaaa
    13321 acacttgcag aactgccaga aaacgcacgt aactatgtac gtcgtatctc agagcttgtt
    13381 ggtgtacgta tctcaacatt ttctgtcgga cctgatagaa cacaaacaaa catcttagaa
    13441 agcgtctggg cgcaaatcta aggataaaaa cgacgactga atcaggacgt tcttaccaga
    13501 gcgagtcgaa gtgtttatct atacgataat aataacttga agaggtagtg aaagagacgt
    13561 ttagccttat tgccgatagg ctgtctcttg aacactgttt attcagaata agggactgtg
    13621 acaaaaaccg tgtcacagtc cctttttccg aa
//
LOCUS       DAFLWQ010000077        13413 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.080, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000077 DAFLWQ010000000
VERSION     DAFLWQ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13413
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.080"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            208..1014
                     /gene="proB"
                     /locus_tag="L1V16_002240"
     CDS             208..1014
                     /gene="proB"
                     /locus_tag="L1V16_002240"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBN1276563.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1011..2258
                     /locus_tag="L1V16_002241"
     CDS             1011..2258
                     /locus_tag="L1V16_002241"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBN1276564.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2334..2678
                     /locus_tag="L1V16_002242"
     CDS             2334..2678
                     /locus_tag="L1V16_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276565.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2795..3121)
                     /locus_tag="L1V16_002243"
     CDS             complement(2795..3121)
                     /locus_tag="L1V16_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276566.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3494..4696)
                     /locus_tag="L1V16_002244"
     CDS             complement(3494..4696)
                     /locus_tag="L1V16_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1276567.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            4813..5328
                     /locus_tag="L1V16_002245"
     CDS             4813..5328
                     /locus_tag="L1V16_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBN1276568.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5527..5973)
                     /locus_tag="L1V16_002246"
     CDS             complement(5527..5973)
                     /locus_tag="L1V16_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBN1276569.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6020..7498)
                     /gene="msr(C)"
                     /locus_tag="L1V16_002247"
     CDS             complement(6020..7498)
                     /gene="msr(C)"
                     /locus_tag="L1V16_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBN1276570.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(7852..8481)
                     /locus_tag="L1V16_002248"
     CDS             complement(7852..8481)
                     /locus_tag="L1V16_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBN1276571.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8465..8929)
                     /locus_tag="L1V16_002249"
     CDS             complement(8465..8929)
                     /locus_tag="L1V16_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1276572.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9416..10684)
                     /locus_tag="L1V16_002250"
     CDS             complement(9416..10684)
                     /locus_tag="L1V16_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBN1276573.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(10915..11652)
                     /locus_tag="L1V16_002251"
     CDS             complement(10915..11652)
                     /locus_tag="L1V16_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1276574.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11719..12288)
                     /locus_tag="L1V16_002252"
     CDS             complement(11719..12288)
                     /locus_tag="L1V16_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBN1276575.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12416..13288
                     /locus_tag="L1V16_002253"
     CDS             12416..13288
                     /locus_tag="L1V16_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1276576.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
BASE COUNT         4045 a         2759 c         2427 g         4182 t
ORIGIN      
        1 tactcctatt ctaacatatc cgaggctgta aaagactttc tttacaaatt cttcaagaaa
       61 ttctgctatc ttaaagtaaa ccattaattc gttctttttc caaacgacta caagttgtac
      121 aaaaaaacta ttttttacat gactttactc gtcaaaacaa gtagaataga acgaaattaa
      181 tgagtggata tttgattgag gtgtcacatg cgtaaagaaa ttaaaaatgc aaaacgaatt
      241 attgtcaaag taggaacaag tacattgatt tatcccaatg gaaatatcaa tcttgcggca
      301 atcgatcagt tagcttttgt cctttctgat cttagaaatc ggggaaagga agtgatctta
      361 gtctcatcag gagctgtagg cgttggtatg cataaattac atttgtcaga acgtccgact
      421 ttgattcctg aacagcaagc tgcggcggct gttggtcaag ccgaactgat gaatatctat
      481 aatcaaagat tcagtgtata taatcaacag acggcacaga tcctcgtgac aagagacgtg
      541 gtagattatc ctgaaagtcg taaaaatgtg aggaatacat tggaacagct tttgattatg
      601 gacacgatcc ctatcgtgaa cgaaaacgat actgtagcag tggatgaatt agatcatctg
      661 acaaaatttg gcgataatga tcagctgtca gccatcatgg caaaacttgt cgcggcagac
      721 cttttgatcg tcctttctga tatcgacggg ttttattcag ataatccgac tacaaatccc
      781 gaggctcaga tgtatcgcta tatcgataaa atcgatgaaa agattctggc acaagcaggt
      841 ggtgctggta gcacatttgg aacaggcggt atgcagagta aattaaaagc cgcttctagg
      901 atatttgaag caaacagcgc aatgatttta gcaaatggaa aaaatccggc aattattttt
      961 gatattcttg caggaaaaga agtaggtact ttatttaagg aggacttgaa atgactgact
     1021 tgatgcaatt aggacaacag gcaaaagata gcgcgcaaca actagcactt atgcctacaa
     1081 accgcaaaaa tgagctactt gttcaaatgg cacaaaccat caaaaagaat caacaagcga
     1141 tcattgaagc aaatcataaa gacttagaaa aagcagtcga aaacaatatc agtgaaacga
     1201 tgcaagaccg cttgcagctg acacctgagc gaatcaatgc catggctaca gagatcgaaa
     1261 aaattgcttc gttagacgat cctattggaa aagtagatga gatgtggacg aacaccgacg
     1321 gattgagaat cggcaaaaag cgcgtgccac taggcgtgac cggcatcatt tacgaatctc
     1381 gtccaaatgt cacgacagat gcagctagtc tagcattcaa atcagggaat gccgttatcc
     1441 ttcgcggtgg caaagaagca ttcttctcga atcaattatt agtccaatta ttgcagcaag
     1501 tactggtcag tgctggcgaa tctccttatg ccatccagtt tgtcgatgat acttctcatg
     1561 aaactgcagg acagttgatg cgattgacag aatacttaga tgtgctgatt cctcgaggcg
     1621 gagcaaaatt aatccaacga gtcaaagaac aggcaacggt acctatcatt gaaacaggta
     1681 caggaaataa tcacgtatat atcgataaag aagcacagtt atctatggca gtgaacatca
     1741 tcgtcaatgc aaaagcttcc cgtccatctg tctgtaacgc ggcagaaaca ttgctgatcc
     1801 attctgagat cgcacctttt ttcttgccag ctattgaaaa agaactggta gaacacgggg
     1861 tctctttacg tgcggatgct cgtgcgttag aatatctaga gacggctgct ttagcagaag
     1921 acacagattg ggatactgaa tatctagatt atatccttgc tgtcaaagtg gtcgattctt
     1981 tggatgaagc aattgcacat atcaatcggc ataatactaa acattcagaa acgatcgtga
     2041 cagatagtta tgcggctagt caacgtttct taaatgaagt ggacgcggcg gctgtctatg
     2101 tcaatgcctc cactcgtttt acagacggat cggtatttgg ttttggtgca gagattggta
     2161 tctctactca aaagttgcat gcccgtggtc caatggggtt aaatgaatta acttccacaa
     2221 aatatatcat ttatggcgat ggacaaatcc gcgaataatg tttcgtgtga aacattattc
     2281 ccgccttttg ccttttttct gtaaaggttc tatccaacta gaaaggtgtc aatatgtttg
     2341 aaattttaat gatttttttt atttacctta tttctctgaa tatcgctgct tttctgggag
     2401 tcggtatttt atcccttttc tttcaattca aaaaacgaag catagggagt caacgggaaa
     2461 aatggtcgca gtattttgac aaaatcgggc aaaaagggct ggttacacgc ttgcacatta
     2521 gttacatggt tgcattatgc ttattagcga caatcaatta ctattctttt ttcgatcatt
     2581 caatcgctta tacgattacg ctactgattg ctgggatttt tcacttatct tataaatatc
     2641 agctgaataa aaaccacttg aatcggactt tccgctaaaa aatatccgta cgataagtag
     2701 agtgccttga agatcggcaa aaaactgccg gactttttag aggctgtgac aaagattttg
     2761 tcacagcctc tttttccata taaacggcgt tcgcctacca gctgcctggt aaatctgttt
     2821 cctcttcgtt aagaagcgaa aatccgtcaa atgtttcgcc atcataataa cgaagcagct
     2881 catccatgga caagttcatc gttttttctt tttcttcttc cgctgattca gccagtagct
     2941 gttcccgata cacctgatac ataccagcta ttttttgctg catcgctttt ctagtttcac
     3001 cttccgcatt gattattggc aattctttga tatagccacg ataaatcaac cgatcatctg
     3061 aaaattcaat gggtaattca acgagtgtca acccgacttc ctgaaaatat tcttccagca
     3121 tctattatcc ccccattctt tttcttaaat gaattttagc ttacctactg aaaattttcc
     3181 agtttcatta ttttgagaaa aaaagggaat gtgacaaaaa tcgtgtcaca tccccttttt
     3241 ccgaataaat ggtgttcttc tgccaactcc tcaatcataa gtcacaatat tcaacaaaca
     3301 tgagaaactg ttttttgaaa ttgttccttg tgattcagag ttaaacgaca gtctcacaac
     3361 ctcttggtaa acggcgttca aaagcttgca tctgcggtaa taagcccaac caaacgaaaa
     3421 atatgagaag ctatttttgt ttggctgttc ttatgacttg atgcaggaca gctttttcac
     3481 aacctctgat ttcttattct tcttcatttg tagcaaaata attacggtga taaatgatac
     3541 aacatacact gataagaaca atggcacctg caaaataaaa cgcatagctt tcaccaatat
     3601 gttcaccaat cacacctgca ataaatggtg ctaaagctcc accgaaaaag cggacaaaac
     3661 tatagctgga cgaagcaacg tttcgttgca gacctggtat ttccatagca atcgtcgtca
     3721 acagtgtatt gataattcct tggaaaaatc ctgctaacac aatgctgatc ggtacaagga
     3781 ctggcataga agttccagct cctaataaca gcaaacaaat aatgaataag acaaatgctg
     3841 ctaaaattgt ccgataagtc gtaaacttcc gctcaagagc cggtgcaacg aaaatcgaag
     3901 caatagccag aagcacaccc cagccaaaaa atacaaaacc gacttctaat tcagaatagc
     3961 caatcaataa aaatggcgca tacgcaagta aagtaaagaa tccgaaatta tataacaatg
     4021 cgattagtcc aactgaacga agtttatgat tgcttaacgc tttgacacct tcccaaaggc
     4081 ctacttttct ctttggtttc tcagtttcag gtaaaagtac cgctagggct ataaaaccgc
     4141 aaaacatcaa aaatgctacc ccaaaaaatg gataacgcca tgaaccactg cccaagaccc
     4201 caccgactag agggccaaca gccattccgc agccaagtgc tgcttcatac atcatgattg
     4261 ctttttctgt gttaccaact aaaatactga cgatcgttgc taaagcagta gagacaaata
     4321 aagcattccc gacaccccag ccggcacgta acccaatcag cattccgata ttcccagata
     4381 atccgccaag accagcgaat acaacgatga taaacaatcc tgtcatcaat gtttttttca
     4441 aaccgatccg actagataag aaacctgtaa atagcatcac cacaccagtg actaacatgt
     4501 aactagtaaa taacagggtc gtttcagctg gcgtagcgtt taactgtgca gcaatcgttt
     4561 ttaagattgg gtctactaga cccactccca taaaagcgat catacaggta gctgctacaa
     4621 ctagcgctga acttttcccc tttgtttctt catttgtttg ttcttgtata tctatttgat
     4681 tctccaatat ttccatccct ttctctctat tagcatcata catgatttat tttacatgta
     4741 aatatgcaca tgtaaaacgt ggaaacttta ctgtgatata ataaagaaaa taagacgaga
     4801 ggtaggattt ttatgaatac tttagcctat atattattat gcgtgctttt atccaaacca
     4861 cgttctgggt atgaattgaa gcagctgatc acaatttttt gggaagccca tcacagtcag
     4921 atctatacaa cgcttgccaa gttagaccag cagggttatg tgaccgtttt ggacaaagac
     4981 gagcactctc aaaaaaagat ctaccacttg actgatgaag gacgtgctct tgtagaggaa
     5041 tggatcaaag aggaaactcc cgctcctacg caaaaagatg aatttctagc aaaaatctat
     5101 gctttttcga cgctcgataa aacaacagct actggactgc tattcactag agaacaacag
     5161 ctgaacaaaa tcatgcaaaa aaatcaaaaa aaattgaatg acctctcgct agacaagaaa
     5221 caagaatttg gacgttatgt tgtgatccag cgcagaatta tgctttgtca gcaggaactc
     5281 caatggtgtc agcaagtaag agaacaaatg cagcagtttt ttgagtaagg gataaacaga
     5341 acctttctag aaatatctat tgaagagcaa attatcttca ataaaagagc aatacagttg
     5401 gaaaagaaaa agcgatccga acgacaggcc aaaacctatc gttcggatca ctatttttct
     5461 agaactgcat tcaagagact atgacaaaaa gcatgccaag gccttttttc aaataacagt
     5521 gttccatcat tcattacttt gaattgcttt tagcacactt cttgaaagcg ggccaacgat
     5581 gatcaactgc aacggtaaag cggcaatcac attcattttc caagcattca tataagcaga
     5641 gaataattga tcaggtattc cttgttccat gatcacaccg aataaagaca tacatgtcac
     5701 cattcctaaa accatcaagc atgaaatagt taagatcatt tggaccttgc tttctggatt
     5761 tactggtagt ttaaaggcaa tttttttcgc cagcacaccg atgatgaaga catccaaaat
     5821 gaaagccacc acgaatccag gcactagacc aatcaacaaa cttgataaat gaagatcttg
     5881 atgcagccat aaattatacg cgctcatccc caagaccatc aaaaaacaca tcattgttgt
     5941 aaaaattatt ccttcttttt tatttgtagg caatctgtac cactccttta aatttgtcac
     6001 gaaaatcatc gtagcacatt taaaaatttc tcgtaagtac tttttttatt ttctgccctt
     6061 ttatttcata aacttcatca gccgtacgct cgacaaagta agaatcatga gaagtaaaca
     6121 aaatcgttcc cggatatatt tgcattagct tctctaaagc ttcgatcgtt gccatatcaa
     6181 taaaattagt cggttcatct aacagcaaca cattacttgg cttagtaaaa agcaaagcaa
     6241 tcgtcagacg ggtcgcttct cccccactta atgtacataa cggtttcgtc aaagtttcct
     6301 gagcaaaccc taagtgattc agcaaactac ggacaagcga ttctgaaaac tctgtttgtc
     6361 tcatgacaaa acgaatgatg gattcttcag atgtcatttg ataacccttt tgctgatata
     6421 cttgaaagct tactttcgga gagagaagga ttccttctcc ttgtttgcgg atatgttcta
     6481 ataaggttgt cttacctgaa ccattttcac cgacaatcgc gattttttta cctaaagaaa
     6541 actgaaaatc accatttacc agtaatgttc tcccacttct ttccaattgg acattttgtc
     6601 ccatgatggg atagcggctg tggagttcaa gagattttgg tactggaaaa cggatttgtt
     6661 tcatctgctg cggcttggtt gtttctccta ttttttggag tcttctctct aatgttttcg
     6721 cattcttttg gatggctttt tgtacactgt ctttttgttt agaggaagac aaccgatccg
     6781 gtctgatttg ttgctttttc tttttactgg acactttttc caacttttcc gcttgttttt
     6841 tcttttcttg gatcgatttt tccaatcgtt ttttctcttt catgatcgac tctgcttctc
     6901 gtagctgagt ctttttctcc aattcctttt gagtgagata ggcactataa ttccccgaaa
     6961 actctcggat ttctccgtct tttacttccc agattttcga tgctagctca tctagaaaat
     7021 agcgatcatg actaacaaaa accagcgtac cataataata acgaagctct tcaatcagtc
     7081 gatcaatact ttttctatct agatgggttg ttggctcgtc tagaagcatc ccttgttcat
     7141 aagaagaaag aagacgtatc aactcgatct ttcgttcttc ccctccgctc catttccgct
     7201 ctgaagtttc ttccagtctt aactggaaat gactggctaa ttccaaattt aggtcctttg
     7261 cttcagcgag ataggttaat tgaggcaggt agttgaaggt gatctctgtt tggattttcc
     7321 catgatcggg aaaaagttca ccggctatta gtttgagcaa agtcgattta ccgacaccat
     7381 tttctcctat gatccctata cgatcttgct gatagacacg aagagaatca atagatagtt
     7441 ctagctggtt gccaaagctg acttgtagat ttgttatatt tactgctaaa ttttccatat
     7501 gttttacact cctatttcat gtaaaacaac aattatcgat actaaaaaag agcagaaaaa
     7561 tctgtttgca aaaaaactgc atcacatctt ttcctactct gaacgaaata actatgacta
     7621 aatcaccaaa tctgtcatag ctttcaccta ttctactgtc gttcgaaaaa atggacatac
     7681 tccatccatg aaattgttgt ttatacatgt cttttgaatt tatttagttg ttattcaaaa
     7741 gttcgaaacg taatttcatc gatgcagtca tttttccgac ctcctttttt attaggttac
     7801 cacacacgat tcaaaaaaag caatagctac tgaatagtaa ctgaaaacct tttattcgaa
     7861 cgtagtgatc ttttctggtg ctaaacgaac agactcgtaa ccttcttcta ccgcttttcc
     7921 tattgataaa ataataactg gaacataacg gtctttatcc aaaccaaatg cctctgccaa
     7981 ctgatctgct tcgactccac caattggatt tgtttcatag ccatgatcac gcgcaactaa
     8041 catgaattgc atagccgcta agctagaatc gactttgact acatcgttca tttcttctct
     8101 tgaaaaactc ttgtaataag gaatgatcgc agctaattgt tgatctctga cttcttttgg
     8161 catcttccct gattcgtaag cttggttata gatttcttcg ccatattcgt aacattgcat
     8221 atcgccaaaa atcatgacca ttgcagaaga agtatcattt tgtctcgtat tgaaacggat
     8281 caaaggacgc aagatttctt ttgcttcctc gctttcagcg accacaaagc gccatggttg
     8341 catattgaca gaagaaggtg cagtcgtcgc ttctttgatc atttccagca tttcttcgtg
     8401 tgggattttg tatgtttcat catatacgcg aacggatctt ctaccagtca taattgttga
     8461 aaaatcattt ttttgttcca ttattattaa cctctttcgt ttctgttgtt atattgcaaa
     8521 gttgggtatt caatttatct aaaagtgtta gaaattgttt catttctaca tcgctgaaag
     8581 ccggggatag cacggaacct gtatctttat ggtccatttc acaatgctcg attttcttct
     8641 gggctttttc tgttagcgct acatacactt cccggttgtt ctgaggattt ctctgacgcg
     8701 aaacatagcc atttgcttcc aataccttca gatgacgagt aactgctcct tgatcaatct
     8761 gcaacttttc ttgcaaactg ctttgtagca atggattttc ttctttcagt ctcatcatga
     8821 tctcgtatct agtaagactt ataccgatat tttcttcaaa gatctggacg attttttgat
     8881 cggctaattt gatttgatat aaaaggtgac taatctcttc taaagacata atttcctcct
     8941 ttctaataat tgactcgtca acgattgact tgtcaataat agaataaaaa aagaaaaaag
     9001 tcaaagaatc agctgtgtaa taaaaaaaac gctctcaata gaaaagtata gagaaaagaa
     9061 attttttgta gaatgaacgg aaaaaatgat aaagaaagca caacgctaaa accaagatta
     9121 ttgattctta tcaaactata gaagatagct cttctgcagt agaaaatttt acaccgccaa
     9181 aaatttccga aatcgccttt tgcaagaatc ccgtcgaata ttagaaattg gatcagtatg
     9241 cttaaacagt aataaaaaag ttatgacaag atgttgtcac aacctttttt gagtaaacgg
     9301 tgttcaaaaa cttgcatctg cggtaataag ttcaaccaaa caaaaaacat gaaaatctgt
     9361 ttttgtttgg ctgttcttac tacttgatgc agggcagctt tttcactacc tctttttaat
     9421 aaccataaaa tcctattcct tcatatctcc agcccatcgg tgttagccaa tctctttcct
     9481 tagcactcaa ggtatagtga tgggtaccag ttttttcatt tggattaaat agtcgataaa
     9541 ttggcttgga accaccagaa taaaaactta gaccttcata acgccaaccg atttttgtta
     9601 aagagttgat ctcagattgt gccattgtgt aatgatggtc tccactgtaa ggattgtata
     9661 aacggtagac aggttgtccg ctgtttggtg cttgccaagc aatcccttca tattcccagc
     9721 ctacagttgg cagataattt ttttctccgg cattcaatgt atataaatgt tctcctgtat
     9781 gacggttata cagacgatac atcggagaag ttgaagttgg tgctgtatca tactgtgtca
     9841 gattataggt ttcgattaca ttgttcaatg tagaaccata attaggcgca gtggcataac
     9901 gacctgttag ccaagccgta gcatctttgt aagagttcgt attgcttttc catgcaccgg
     9961 aatagtagta aacgcctggc tgaaaagaag tcgtcttcaa taccgttacg ttatcttgca
    10021 atgattcttt gtacgaagga tattttctaa aagcggcatt caccgtaatc cattgcccat
    10081 tcacatattc cgaagtaggc atcgtaacag attggccatt atagcttcct ttaatcccaa
    10141 atagattgta attaggggca gaagccaaag tactgttccc ccagccactt tcaacgatgg
    10201 cttgagcaat catgactgat gcatataagt cattggcact tgccaaactt tgtgcagttg
    10261 aggcaatact atcaatgaac gcttgttgag aattagcaga tgagcgagca taaaaagcat
    10321 agccagtata gttttcgaat tcagacaaat ctgcttgatg ggtatgtgtc aatgtttgcc
    10381 catctgtcaa ttggttcgtg atttcttctg cattctctgg attgttctga gcttctgctg
    10441 atgtactgtc ttcggtttgt gtttgttctg ttgtttcagt tgttggttct tcggttgaaa
    10501 ttgtattttc tgagacagta gctgactgca aagtactctc tgtatcgttt tcaattcctg
    10561 tttctgaaga actcgatgtc tgagttgcga cagtttctgt cgattcttca gctagcactg
    10621 ttgtgttggc aactgctaga tttcctaaaa gaataacgct aaataataaa ttctttgctt
    10681 tcatcttttt tctcctttga attatgaaac ttttcctaaa taacagtgta actaaaaaag
    10741 taaaagcaag tcaatgtcca tatttaaata acatttgttt ctttttgata aatttgcttt
    10801 ttctacataa aaagacgtaa atgaagaata ttcttctcca ttcacgcctt aaattgatgg
    10861 tcgtttgaat aactatttaa caagtaattc tctttggata ttatccgtta tggattatac
    10921 ttcctgtgtc gtcggacgga taatcatgtt actgacagac atccggtctg gcgtttctat
    10981 cgcaaatgct acagcagaag ctatatcttc ggaggtcaat ccccattctt tttgcgcttc
    11041 atgaagttca agagcagcct ttttgtcgct gatggtttga tataattcag tttgaacagc
    11101 tcctggagag atgatcgtag atttgatgtt attttgccgt tgctcttgac gtaatccttc
    11161 catgattgca cggacagcaa attttgttcc gcaataaacg gcggaatcag gataaacaac
    11221 atgtcccgcc acagaatcag ttgaaatgat atgcccagat ttttgttttt ccatgattgg
    11281 aagtacggcg gaaattccat ttaacacacc catgatgttg atatcaagca tattttgcca
    11341 ttcatcacgg tgaccttcaa ctaatggagc ggttggcatg attcctgcat tattgtacaa
    11401 tacatcgatt cgaccgaact tttccatcgc taaatcgata actgcttgga cttgtgcaaa
    11461 atctcttaca tctgctgttt gaatatatag ctcagcttct ggtaaagatt cttttattgc
    11521 ttttaggcga tcttctcggc gtgcagctat aactagttta gccccttttt ctgctaatag
    11581 cttcgttgtt gcttcaccga ttccgcttga agcgcccatg atgacaatca ctttttctga
    11641 taaatcattc attctattct cctcctgttt tgaaaaatct cttgcttata ctcactatct
    11701 cttatttcat cttactgttc aaataatccg ttcgacaggt ttgacgattt tggcagggat
    11761 tcctgcaacg atggtattgt ctgggacatc tttcgtaaca gttgcattcg ctgcaacaat
    11821 ggcattctcg ccaatcgtta cgcctggcag aatagttgct cctgctccga tccaagcatt
    11881 tttcttgatg tggattggct ttactaacaa gcctcttcgt tcttttggat cggttagatg
    11941 gttcaccgtg atgaggttga cacgaggacc aatcaatact gaatcttcta aacagatgcc
    12001 acctaagtca acgaacatca cttgacgatt gataaagaca tttttcccta tactaatatg
    12061 tttgccgaaa tctgtataaa aaggcagcag aacagtcacc gtatcatcta ctttgtcact
    12121 aatgatattt tctagccgtt tgcggatatc tgctggttca tggtacccag tattcagcgc
    12181 tgctaaaggc tcttcgtttt cagcttggat ctgatggatc acttcaaaga gcggatccgt
    12241 tactcgaatc tctttattga cgatttgttt ttcgatgagg cttgtcattt tgctccctcc
    12301 ttttatcctt actttataac ggacggctta tcatgtctaa tacttataaa acatacttaa
    12361 ctattccttt taactatact tagtggtatg cttttttaaa aacaggaggg aaaaaatgga
    12421 tattcgtata ctgacgtatt ttttagcagt agctagagaa aaaaatatca gccgagcagc
    12481 aaaatctctg catatcacgc aacctactct ctcaaaacaa ctgaaagatt tagaagaaga
    12541 acttggtgtg acacttttca ctcggggctc ccgagagata cagttgacgg attctggtcg
    12601 atatctttat tcaaaaggaa aagaaatctt gtcgttggta gaaaaaacgg cgaacaattt
    12661 aacaaatgac gcaatcatct ctggagaaat ctacattggc ggaggcgaaa ctaaagcaat
    12721 ctctttcatt tctgatagcc ttcattcgtt gatcaaggcg catcctgata tccagtttca
    12781 tttatatagc gggaatgcag atgatatcat agacaaactg gatagcggat tacttgattt
    12841 tggactcgta atcgaaccga caaacaaaca aaaataccag tcatttcgac tgccagccca
    12901 agatcgttgg ggacttttga tacatcgaaa tcatccttta gcaaagcaaa ccgtcatcca
    12961 tccgcaggaa ctgaaaactg ttcctttgat catttcccgg caaacgtcag tggacagtca
    13021 actagctgaa tggctaggtt tcagcataga tcagttatcg atcgtcggaa catataactt
    13081 attgtacaat gcttctttga tggtcgataa cgggactttt ggtgcattag ctctagatgg
    13141 gatcatcaat acttatggga cggaaaaaat attcatccca ctcgatccgc cattacaagc
    13201 ttcactgaat ctcatttgga aaaaagacca gcctctttct cctgctgctc gtaaattttt
    13261 agatgtccta acggagaaat acagttaagt agagtttttt tccttcgctt tcagcttttt
    13321 aacaacgaat aagataagca aaagatccaa cgattaaata acataagttt cttaatttat
    13381 ttcttccttt tatttctgat aattccagta aat
//
LOCUS       DAFLWQ010000078        13212 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.081, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000078 DAFLWQ010000000
VERSION     DAFLWQ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13212
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.081"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            147..1016
                     /locus_tag="L1V16_002254"
     CDS             147..1016
                     /locus_tag="L1V16_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HBN1276577.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1225..2250
                     /locus_tag="L1V16_002255"
     CDS             1225..2250
                     /locus_tag="L1V16_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBN1276578.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2289..3239
                     /gene="manA"
                     /locus_tag="L1V16_002256"
     CDS             2289..3239
                     /gene="manA"
                     /locus_tag="L1V16_002256"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBN1276579.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            3333..5036
                     /locus_tag="L1V16_002257"
     CDS             3333..5036
                     /locus_tag="L1V16_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1276580.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5038..7071
                     /locus_tag="L1V16_002258"
     CDS             5038..7071
                     /locus_tag="L1V16_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBN1276581.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7082..7522
                     /locus_tag="L1V16_002259"
     CDS             7082..7522
                     /locus_tag="L1V16_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1276582.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(7722..8849)
                     /locus_tag="L1V16_002260"
     CDS             complement(7722..8849)
                     /locus_tag="L1V16_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1276583.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8852..9529)
                     /locus_tag="L1V16_002261"
     CDS             complement(8852..9529)
                     /locus_tag="L1V16_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1276584.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9793..11559
                     /locus_tag="L1V16_002262"
     CDS             9793..11559
                     /locus_tag="L1V16_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBN1276585.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11574..12011
                     /locus_tag="L1V16_002263"
     CDS             11574..12011
                     /locus_tag="L1V16_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1276586.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12024..13175
                     /locus_tag="L1V16_002264"
     CDS             12024..13175
                     /locus_tag="L1V16_002264"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBN1276587.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
BASE COUNT         4488 a         2293 c         2731 g         3700 t
ORIGIN      
        1 tttataagag tttttactca ttaatttaca aaaaacaagc aaaatgcgaa ttttctcaca
       61 ttttttttaa caaaatcaaa gttattgctt gaaagaagaa gaatccatcg ttaaaataaa
      121 gcttgacgta gaggggagca agaaatatga aagattttca attgggggct gccacctatt
      181 taaaaagtgt agccattcgg gtgaaagacc gagataaaat gattgatttt tacaagaacg
      241 ttgttggctt tgatttgaaa agagaagaaa acgaattagc cattttagga acagaagaag
      301 ctggaagtga aatgttgctg ctggaagaaa gtcctagagc gaatgatcac atgggggtga
      361 tcaaaaagct gaaccgtttt tcattgatta tccctagcac agaagaaatg gcagatatcc
      421 tttgtcgtat ccgtaaaatg aattatccaa tcaaagaagc tttagaagat catggacgta
      481 tggggatttt gctcgtagac ccagaagaga atgaattgga aatttaccat gaagagaata
      541 agaacgacca aagagaaatt ccagaaacaa tggatcaaga agcattatta agaaaatctg
      601 aagaaaaatt cagtaaacta tcaacaggtt cttattttga aaaaatccat ttaaatgtta
      661 ctaacttaac aaaagaacgc caatttctta atcatgtact tggtttgaag gtacataatg
      721 aagaagaggg catccatgta ttgaatgaag gagatttcca tgttggtttg acagaagcta
      781 gcggaggcgc aattgatttg cctacagatg aagtgattgg acttgatttt ctgaaattca
      841 tgatcgatac tgaaagcatg gaaggactga ttgctcactt gcagcaacta tcagttgatt
      901 tcttcttaga caaaaagcac acagtactca caatctatga tgctatagga atcgaatggt
      961 ggttcgtcag tgagccaaaa gaaaagaata aaactgacat tcgatgcgac gcttaacttt
     1021 ttctttctta acgattgtcg catgtctcgt cattttatga acggtcatac tatcgcttat
     1081 tctagagata gaaagagaaa atagtatacc gggggaaact gcgcggtttt tcgcgcagtt
     1141 tttttgtgta aaaaaggttg attcctcata gattaagctt taagcttgga ctgtaagaat
     1201 ctgatagaaa agcaggagaa aaagatgtat ccacacacga aacagcttat tttgaaaaag
     1261 atggaagaag gattttatcc aggtgtagca gtcgccttca taaaagaaaa tcaagtagaa
     1321 acatttacag ccggctttgc ccaagtcgtt cctgaaaagc agctgatgac agaagatctg
     1381 ttgtttgatg cagcctcact gacgaaagtc gttgcaacca cttcattagt tttacgtcta
     1441 ttagaagatg gaaagataga actcgatcaa ccgcttcata aatatcttcc tgaatttgaa
     1501 aatcagacaa tcactttgcg tcatttactg acacatactt ctgatatcaa aacatggata
     1561 ccaaacagag ataagctatc tcaggaagaa ttgatcgccg cttatttgaa gctagaacca
     1621 ggtgagcaac taggaaaaga agtaaaatat acagatgccg gtacgattct tcttgggttg
     1681 atgctagagg aaatttacca agaaactgca gtggaaatct ttcaagaaca agtattggaa
     1741 ccattaggaa tgatgaacag cttatttctt ccttttcctt ccaaaaaaat cgttcccaca
     1801 gaacaactgc cttcgggtga ggttttgcgt ggacaaactc atgatccgaa agcaagagtt
     1861 ttggctgaac atgcaggtaa cgcgggtctc tttattgatt tgaaagacag cattactttt
     1921 gtccaaatgt atttgaacaa gggaaaaatc cgtaatggtc gttttttaga agaagagacg
     1981 attgattctt tactgcaaga tcaaacaccg aaaaaaaatg gctatcgttc tttaggatgg
     2041 gacttaaaaa aggatgtaga agacggtcat gcgattcttt ttcatactgg ttatacaggt
     2101 acgtttttct tgattgatat aaaaacacaa gaagcgttga tatttttgtc aaatcgcgta
     2161 catcctgtcg atcatcgtgc ggagtatctc atatgtcgag atgaaattgt tgaaaacttt
     2221 ttgaaagaga aagcggtatt accgaaataa tgctataata gctatgaaaa atgagaggag
     2281 tttgaattat gcaggaacct atgtttttaa aaccagtttt tcaagaaaaa atttggggag
     2341 gaagtcgttt acgttcagtc tttggttttg atatccctaa cgataaaatc ggagaagatt
     2401 gggcgatcag tgcgcatcct catggtgtca gtgtagtaga aaatggcgaa ttcaaaggga
     2461 aaagattaga tgaactatgg tcagaacaca aggaattgtt tggccatcct tcagaaccag
     2521 tgtttccatt attgatcaag atcttagacg cagaagatga tctatctgta caagtacatc
     2581 cagatgatgc ctatgggatg aaacatgaag gtgaattagg aaaaactgaa tgctggtata
     2641 tcatcgatgc tgaacctggt gcagaaatca tctatggtca tcatgcaaag acaagagaag
     2701 aactagctga gatgatcaaa gatgggcgct gggatgacct tttgaagaaa gtaccagtta
     2761 aaaaaggtga tttcttttat gtaccaagcg gaacgatcca tgctattggt aaaggaatca
     2821 tgattttaga aacacagcaa agttctgaca cgacttaccg cgtgtatgac tacgacagaa
     2881 aagatgcgca aggacaaaca agagagctgc atatccaaca atcgatcgat gtaacaactg
     2941 tccctgcgaa aacaccagaa ttacaaatca aagaagtccg aaaagggaat tcatcgatcg
     3001 tcacttattt agaaactgag tttttcaatg tatatgagtg ggatattaaa ggaatcacat
     3061 ctttcaaaaa acaagcccct tatacattga tgacggtaat cgaaggagca ggagaccttg
     3121 tcgttgacgg aaaaacatat ccattagaaa aaggaacaag ctgtattatt ccaaatggcg
     3181 tttctgagtg ggcggtccaa ggtgaactag caatcattgc gactgaacca ggcaaatagt
     3241 tcccagatag ctgaaagcag cagacggttt ttcgtttgct gctttttcta cataaaatcc
     3301 gtccatcaat aaatagaagt atggtgaaaa agatggaata caaatggaaa gcaaacaaca
     3361 gcagtcgcgt gtctatgaaa caactgagaa aagctggaca tcacttaaat gaaatgatca
     3421 tgccaaatct aagtctgttt atcgcttggg gaatcttgtc attagcaaca aaaggtgtgt
     3481 ctggcgattt gcacaccaca ttagaagagg tatgccattg gatgatccag ctgcttttac
     3541 ccatcttgat cagttattca ggcgggaaat cggtaggggg acaaaaaggg gcagtcgccg
     3601 gtgcaattgc ttctttaggg ttgatcgctc gttccaatgc tccacaaatc gtaggagcga
     3661 tgattatcgg gccgcttgcc ggcatcgtat atgaacaatt tgtttctaga ttccacgtga
     3721 aattcaaggc tggatatgaa atgcttgtca gcaacctact agtaggactg actggtagcg
     3781 ttatttgtat aattggaatc gtttttattg aaccagtttt aaatagtgtt cacttgttgc
     3841 tcgcctccgt tgtgtcttgg ctagtcacaa tgaatctgtt accacttgtc agtctgatct
     3901 tagaacctct aaaagtacta tttttcaata atgcaatcaa tcatggtgta ttgacacctt
     3961 taggaatcga attctcacaa acagtcgggt actcttcctt atttttgatg gaggcaaatc
     4021 ctggacctgg tttagggatc ttactttcta tcctttgttt tgcagaaaaa caggaaaaag
     4081 taaatgcgag tggagcattg atgatccatg cgattggcgg gattcacgaa atctattttc
     4141 catttgtctt gctgcgaccg tatctatttt tagctgtaat ggctggtggg gcaagcggca
     4201 cgttgatatt tcaatggtta gatacgggat tagctgcacc tgtatcgcct gggtcactac
     4261 tcgtgatttt tgccaatgcg ccttatccac aactagctgg ggtaagtata gggatagcaa
     4321 tcagtacatt tgtgaccttc atttgtgcag cgatactatt gaaattacca aataaagaaa
     4381 aagagaacaa aacggtcaaa gaaaggggag aaatcttgga accatctatc attcattccg
     4441 tcatttttgc ttgcgactca ggtatgggat caagtgctat gggagccgcc ctgctgaaaa
     4501 agaaattagc agcagaaaaa atcgatcttt ctgtcggata cagctctatc tatgaattga
     4561 ataaccaagt aaatcagctg gttatcgtgc aacatgaact agcgggtctt gcaagagaaa
     4621 aagtacctca aagtcaaatc tatgtactgg atcacttttt ggaaacagat atcttgctgt
     4681 cacgaataaa agaagcgatc caatttccaa agcgggaaga aaaaaaagag atagcagata
     4741 tcacagaaca aaaaaagtcg cctgctaata ttgtattttt gtataaaaac aacagacgcg
     4801 gctcacaaac tatgggcatg acgattttaa gtcaattagc aaaaaaagcg aaaaaacagt
     4861 ttgttatctc aaaagaatca atagaaaaaa tcaaaatcca agaagaaacg atttatatcg
     4921 cacaaagaga actagctgta actgaacagc tagaagaaaa gatccctcgg ctagttctag
     4981 ttgaacattg ggtagctacg aatgaatacg aaaaactcgt gaagggagaa atataagatg
     5041 tatttatcgc ccagagaaaa acaattatta gcagaatttc tcagtagccc gtcacctgta
     5101 tctatccaaa aaatgatgaa tttattgaag gtcagtaaac ggactattta ccgcgaatta
     5161 gataatcttg aagtctcatt gaaatcggta aatgcttctt tgaaaaaagc agctagaggc
     5221 tcatttgtca ttgaggcatc agaagaagta ttagagcaat taaaagaaaa tacagatggg
     5281 aaaagtaatg acttatccac tgctaaacga caacacgcga ttttagccga gttgttactg
     5341 acgacagagc cgttgagtct tgctcatttc atggaatcat atcgcatcag taataccact
     5401 ttttatgcag atatcaaaca gttggaagaa agtattcgcc aactgccttt ggaaatcatt
     5461 cggaaccagg gatacgagat cgaaggaccg gaaaaatacc gccggcttct gacagcgaat
     5521 gtattagaat tagaaatcaa tgaatatgaa ctttttcata gtatttcttt cgatgcatca
     5581 ctgaattatt tttttcgatt cgttgatccg caacatctat ctcttgcacg caaagtaatc
     5641 ggggaagaat tgatccaaaa aaagaccaat ctaagtgata gaaagcttga acatttggtt
     5701 ttgatgctga cattgacgat ggagcgtgtg actaaaaatc atttactgac aaatgagaca
     5761 tataatagtc tggcaaacaa agaattacta cagacagcta aacgattgtt ttcacggatc
     5821 gcttctgaga caaaacaact ttatccagta aatgagatcg tcttttttgc aggattatta
     5881 aatgacttca cgaactcatt tgatcagaat ttctttgaag agacgttcga tacacagctt
     5941 gcttatttag taaaacaact gattcaagaa gtaagtgaag agacgaatgt ccatttttat
     6001 gaagatgaaa ctttgtacaa aatgctgttg actcatttat ctggtgtgtt ttcaagagcc
     6061 gttttacaag aagagacact gaccaatccg attttagaaa aaatcatggt tcaatacgag
     6121 gaagttgcga atgcaatccg taaagcagta gagcggattt ttcaagaaaa aaaattatcc
     6181 gaagaagaga tcgcttatat ggtccttcat tttgcgaatt cattggaacg aagtccgaaa
     6241 gaaagcaata tcagtattgc aggattttcg ccaagtggat tagcttctac tagcatgttg
     6301 gaactacgat tgaaaaggta ttttcccttc atccaacaaa ttcatttcta tcggattgct
     6361 gatttaaaaa aaatcgattt acaagaagaa tatgatgttg ttatttctac atctatttta
     6421 ccaggatacg gtggaaaata tattttagtc tccccgctac tgctagaaga tgaagtcaag
     6481 cagctaaaag aagctttttc gcatattgag aagaaaaaaa ggcaaaaaat tacgtataac
     6541 agcaataacg agtggatgat agaagatact tatgaggaaa caatgcattt catggatcaa
     6601 atcaatcaat tactcggtcg tttttttatc caagaactgg ataatcctga gacgatttcc
     6661 gaaacgattc gcagcttatt tccttatttt cctgaaggac tagtaacgga tgaagaggtg
     6721 gttcatcgcc ggctgcttaa gcgatatgaa caagcaccta tcggtattcc tcatacaaat
     6781 atggggttat tccatacatc cagctcattg atttctaaac cgatcttttg tattttcaat
     6841 ttgaaacatc cgttgaccat tgaagggatg gatagacagc cagtcgattt gtcccgtatg
     6901 ttagttatgc tggcgccttc gccaatccaa gaaaaagacg ggattctttt aggaaagatc
     6961 agtggagcaa tcatcatgaa tgacttgaac accgagatct tccgctcagg aaataaagaa
     7021 atcgtttatc agttgttagc gaaaatcctg attgaagaaa taaagaaatg aaggtgaaaa
     7081 gatgatacag ctaccagcag aaaaaatatt gctcgatcaa tcctatcaaa attggaaaga
     7141 agcgttgacc gagatcggcc agtggatgac ccaacaaggg ggaatcaaac cggcatatat
     7201 ccaatcaatg atcgaaagac aagaaaaagc gagtgtctat atcgggaatt tcgtagcctt
     7261 gccacatggg actgacaaag atgaagaagt agtagaagaa ggaatctatt tagtccaagt
     7321 gcctgatggt gtggactttg gaacaaaaga ggaaccaaaa atcgcgacac tcttatttgt
     7381 agtggcttta aaaaaagaac atcagttagc ggtgctccaa gatttagcct ttttctgttc
     7441 agacatcgac caagtaatgg cgctcagtga tgcgaaaacc attgaagaag tccaaatgat
     7501 ttttgaacat ggacatatat aaccaatgtt cacagtaaaa aaagctgcct tgcatcaagt
     7561 aataacttca accaagataa aaataagagg agctattttt gttgggaggt tcttattact
     7621 gcggatgcaa gcttttgaaa actatttatt ctagaaaacc gtttatttga aataggggac
     7681 ggtgacaagg tttttgtcac cgcccctatt atttttgtgt tttaatagct cttttttata
     7741 tagatagtgc ccatacctat gaataataaa acgatactcc atataccaag tgtcaagata
     7801 ccattcatga aagtaacctg ttctgaagct agtggcgaga aaatatctcc tcctatgatc
     7861 acattttgaa aatcaacata agaagttggc aagtaatgac tgattgattc tatccatcca
     7921 atcgaagaaa acaagcgata ctctgctaag aaaagacaaa gaagtgtacc taaaagattg
     7981 actagagaat gttcaaataa agcagataga agaaaactga ttgtacttaa aaagagcacc
     8041 cacaacaaca ggaacagaaa gctctggaaa agatactcat acatcggaag gattcgtatc
     8101 tcctgaccaa tgatcgttcc tacaggataa cggaagtctc ccaaaccatt tttgattatt
     8161 actagtatag agacgatcaa aaatggcatc acgagactta gcatagctgc accataataa
     8221 atggtaaaac ggatgctatg tttctttacc atactatccg gtaatagatt gactagagag
     8281 attacctgct ttcttttttc ataagagatg atggaagaaa gaaacaaggc ggttatacat
     8341 aaaatcaaaa aactagaaat cattcctgaa aaaatatttt cgtagtaatt tgctaaaggg
     8401 agatgcgctg gcaagtcaaa aatagaatat ctttggatct gatgttcttt catataacgg
     8461 agcaactcga cacgtttttg ttgttcaatg attggaattc cttgtctttg accagaaatc
     8521 agtcgatcca gtatatcttt ttcataatga taagttgctt cgaccatttg ctggacattc
     8581 cctgtgtttt ttgcatgtaa gattgcttcg atcagtttgt tgcttttctc taaactttcc
     8641 acaaattctt tctcattctc atcttctttc aacgtttcaa tcaaacgttg catctcttca
     8701 tagttatgat tcagttcatc gaattctgta taagcaagtt tatgatcaaa aaaaagtggg
     8761 aatgcaaaga gcacgaccaa caatagagga aataaaaagt ttactttgtt ttttagtaag
     8821 agattgcgtt caaatgtaag taaagacata gttacacctc atataattta cgataaatag
     8881 ctaaaatctc ttccatattt gaggattctg tgacgatttc tccatttttt agaaaacatg
     8941 ctttagaaca aatcgattgg atattcgcga tagcgtggga agaaagaaga atcgtcttcc
     9001 cctctttctg ccattgtctg atgaggctat tcaagatatc aatacttcct gggtctaatc
     9061 cgttcaacgg ttcatcgaat aacatgacag atgaatcact gatcaagtaa gcagcaagca
     9121 agacatgttg tttcattcct agagacattt ttccaatcgg caaagtaagg tactcagtca
     9181 tcttcaatcg ttggaaaaca gtttggcatt ctactttgct ctgccaatag tatttgatca
     9241 aagtcaaata atcaacagcc gatagatagt cggataactg attcgttgat tctagaaaaa
     9301 agaaagaccg gcgataatct gtataagcag taggagagat gttgtgaagg gacaattgat
     9361 cataagttgt tggcagcagt tgggcaatgc cattcagcaa agttgttttg ccaaatccgt
     9421 tcggggcaat caaagcagct acttctcctg attctactaa aagattcaat tgtcgaatca
     9481 cacgtttttt accacgtttc atgttcatgt ttttgatcag taatgtcata gataggcctc
     9541 caatataaaa tttaataaca taatagaatg gaaaacatct aaattaaatg ctaacaaaag
     9601 ttattgtttg catattataa aaaaattaaa ataacagttt tatttaaaat tgaagttttc
     9661 tgataccgaa atctttttat tttgctgaca tactcaaacc tttggcacaa agtttcgtgc
     9721 caaagtacga ctatttctct ttttagtaag cggatacaat tagagtatca aaaggagaga
     9781 gggagagaca aaatggaacg gacgattccc aaaaacaaca tttcgctaaa agcgagggta
     9841 caaaaattag gcagtacttt atcaagcatg gtcatgccaa atattggagc actgattgcc
     9901 tggggtgtat taacggctct atttatccca gatggttatt taccaaatga ggctttggct
     9961 accatggtaa gcccaatgct aacttatctg attcctttat tgatcggtta tactggcgga
    10021 aaagtaattg ctggtgaccg cggatcagtt gttggggcaa ttgcaacgat gggtgtgatt
    10081 gtcggaacag atattccaat gatgctaggc gcgatgatca tgggacctct tggtggatat
    10141 gccatcaaga aatttgatca gctattccaa aaacggatca aatccggttt tgaaatgcta
    10201 gtcaataatt tttcagcagg tcttatcggt tttggattag cgttattagg tttttctgcg
    10261 attggtccag ttgtcgatgc attgactcaa gcaatggcaa aaggtgtaga gatcatttta
    10321 tctgcccatt tgattccatt gacaagtatt tttattgaac cagcaaaaat cttatttttg
    10381 aataatgcaa tcaatcatgg gattttgaca ccattgggaa ctgaacaagt agcagaggct
    10441 ggaaaatcta ttctattctt gcttgaagca aatcctggtc caggacttgg cgtattactt
    10501 gcttttactt tgtttggcaa aggagcagca aaatcttcag caccaggagc catgatcatt
    10561 cactttttag gcgggatcca tgaaatctat tttccttacg ttatgatgaa accgttatta
    10621 ttcttatcag ttataggcgg aggaatgtca ggaagtttca ttttccaatt gatggatgct
    10681 ggactaagag cgccagcttc tccagggtcg atcattgcga ttctagcgat gacaccgttc
    10741 aattcttacc ttcctgttat tttgggcgtg attgttgccg cagctgtttc gtttggtatt
    10801 tctgcagtaa ttttgaaagc ggatgcgaaa gatacaaatg aagacttcga aaaatctgtt
    10861 caagagacaa aggcagctaa gcaagcttcc aaaggtgccc aaggtattcc tcaaggagct
    10921 acattctctg gcgtacaaaa aatcattttt gcttgtgatg caggaatggg atcaagtgcg
    10981 atgggcgctt cgatcttgag aaaaaaagta caggaagcag acttgcctca aacggtgacc
    11041 aatcaagcaa tcagccaact gacagatgac tcgaatacat tgatcgttac tcaggtcgaa
    11101 ctacaagaaa gagcaaaaca aaaagcaccg agcgcgcgtt ttgtctcagt agaaaacttt
    11161 ttgaattcac ctcgatatga tgaaatcatt caagaattaa gcagcaagca gaaaacatca
    11221 gtttctgaaa ttgagaatga gccagcagaa gagtttcttt cagcaaacat caaacaaatc
    11281 aaagagattc tacttgtcca cgatgatcgt tccggatcag caacaatggg gatgaccgtg
    11341 ctcaaagata tattagacaa gaaccattta actatcccgt taagaaaagt caatatccaa
    11401 gatttaaaag atgaacctga ttcactgatc gtagccaaag aaagtttagc ggaaaaagta
    11461 cagatggctg cacctcaatc cattcattta tcagtcaaca gcatggtcaa tccgcaaaaa
    11521 tacgaatcga ttgcacaata tttgaaacag acagcttaag ggaggaaaac agcatgcaaa
    11581 gtttgccatt cgacatgatc gagctcaatc gatcttttaa aaccaaagaa gaagcgatcc
    11641 gctattgcgg tcagatgctt gtagaagcag ggtgcgttga tgaggaatat atcgatgcca
    11701 tggtagatag agacaaaatg ttatctgttt atatggggaa ttttatcgcg attcctcatg
    11761 gaacagatga agcaaaaaaa tatgtgaaaa aatccggcat ctgtgtcgtt caagtaccag
    11821 atggtgtaga ttttggtacc gaagaagaag aaaagattgc gactgttttg ttcggtattg
    11881 caggagtcgg agatgagcat ttgcaacttg tacagcaaat cgcactttat tgcagtgata
    11941 tggacaatgt tgtccagcta gcagacgcgc tcagcaaaga agaagtaacg gaaaatctag
    12001 caattgctta aggagagaga aaaatgagag cagtacattt tggtgcagga aatatcggtc
    12061 gaggatttat tggagaggtt ttggcagcta atggatttga gattactttc gtagatgtga
    12121 atcacacgat cattgatgct ttaaatgaaa gaaaagaata cgaaatcgaa ttagcagatg
    12181 aatcaaaaga aaaaatcact gtaaaaaatg tcaaaggaat caacaatcaa acaaatccag
    12241 aaaaagtaat ccaagaaatc gctgaagcag atttagttac taccgccatt ggcccgaata
    12301 tcttaccttt tattgctgag ttgattgcaa aaggtatcca agaaagagaa aaggaaggaa
    12361 gcacaacatc tttagatatc attgcctgtg aaaatatgat tggcggttca gcatttctag
    12421 aaaaagaagt gtataaatat cttccggaaa catcatttac tgacaaatat atcggctttc
    12481 caaatgcagc agtcgatcga atcgtcccat tacaacacca tgaagatcct ttattcgtcc
    12541 aagtggaacc tttcaaagaa tgggtcattg acgatagcca aagaaaaaat aaaaaaatcc
    12601 aattaaaagg ggttttatat gtagatgatc tagaaccata tatcgaacgc aaactattta
    12661 gtgtcaatac tggtcatgcg actgtcgctt atacaggtgc cttgttaggt taccagacca
    12721 ttgatgaagc aatgcaagat gcgttagttg tggcacaatt aaaatcagtt ttgcaggaaa
    12781 caggaagttt gctgattgcc aaatgggggt ttgatgcaga gcagcatcat gcgtatattg
    12841 aaaaaatcat tcatcgcttc caaaacaaaa atatctctga tgcgatcaca cgtgtcgctc
    12901 ggacaccatt acgtaagtta ggttatcaag aaagatttac acgtccagtg agagaactac
    12961 aagaacataa cttgacttgc ccacatttga cggcaacaat ggggattatt tttaattact
    13021 atgatcctga agatgaacaa agccgtcaat tgcatgaaat gaagatccat gaaaacttgg
    13081 aacaattgat tcaagaagtc acaggaatca atgatccgaa aacaatcggg aatatcaagc
    13141 aaaacgtgaa ccgttatgcc aagcaagtcg cttaaaatag gatacgaaaa aggggaatgt
    13201 gacgaaattt tt
//
LOCUS       DAFLWQ010000079        13082 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.082, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000079 DAFLWQ010000000
VERSION     DAFLWQ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13082
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.082"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(79..2199)
                     /locus_tag="L1V16_002265"
     CDS             complement(79..2199)
                     /locus_tag="L1V16_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBN1276588.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2429..3607
                     /locus_tag="L1V16_002266"
     CDS             2429..3607
                     /locus_tag="L1V16_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HBN1276589.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3623..4381
                     /gene="aroD"
                     /locus_tag="L1V16_002267"
     CDS             3623..4381
                     /gene="aroD"
                     /locus_tag="L1V16_002267"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBN1276590.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4404..4889
                     /gene="ybaK"
                     /locus_tag="L1V16_002268"
     CDS             4404..4889
                     /gene="ybaK"
                     /locus_tag="L1V16_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBN1276591.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4960..6213)
                     /locus_tag="L1V16_002269"
     CDS             complement(4960..6213)
                     /locus_tag="L1V16_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1276592.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6329..7678
                     /gene="gdhA"
                     /locus_tag="L1V16_002270"
     CDS             6329..7678
                     /gene="gdhA"
                     /locus_tag="L1V16_002270"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBN1276593.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7790..9136
                     /locus_tag="L1V16_002271"
     CDS             7790..9136
                     /locus_tag="L1V16_002271"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBN1276594.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9444..9830)
                     /locus_tag="L1V16_002272"
     CDS             complement(9444..9830)
                     /locus_tag="L1V16_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBN1276595.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(10098..10247)
                     /locus_tag="L1V16_002273"
     CDS             complement(10098..10247)
                     /locus_tag="L1V16_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276596.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            10709..10921
                     /locus_tag="L1V16_002274"
     CDS             10709..10921
                     /locus_tag="L1V16_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276597.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(11199..12998)
                     /locus_tag="L1V16_002275"
     CDS             complement(11199..12998)
                     /locus_tag="L1V16_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBN1276598.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         4289 a         2353 c         2577 g         3863 t
ORIGIN      
        1 ttattctaag atttctcttt accaacatca tttgacaaag agcctaattt tgtcgctgct
       61 ccttttaaat ttattttatc attcggaaga acttgtggtc gttccgtgaa gttcttggta
      121 cgtttgcgtt ttataaagat caacagttga ttgtcccttg tgttcactaa agacactagt
      181 tgacttgtca ccaagagatt tttcagcttc ttttaatttc tctaagccat tcttgtagtc
      241 ataatcactg gtatcaattg ggtctaatcc actattcgta tagaaccgaa gaagatcacc
      301 attattgatt tggtcagaaa cagctaactg tttatcaact ttttctttca gtgaatcaat
      361 ttcattctgt acttcctcag taggttcagt aatagcttca ccagtttcgt tactatagat
      421 cgtaccaccg tagtaagtat attttggtgt aacaaaatca ccatcacgga aagaaacaag
      481 ctgttcatga tctttcgaga atagatcttg tcctaactga atataatttt ttgtatctac
      541 acctagtaag tgaagtaatg taggcaaggc atcaacttgt ccgccgtaag tgtgattgat
      601 tccgccctgt gtttgtccag ggatatggat catataaggg acacgctgca tttgtgcatt
      661 gtcgtagttt gtccaagtag aacttgtttt tccaactaat tcagctagat ttttatttct
      721 tgaattcgag acaccgtaat ggtcaccgta aaggacgatg actgaattat catacaagcc
      781 gctttctttc aaataattga agaattcttg tacggcggta tctaaataat tggctgtcgc
      841 aaagtaaccg ttgatcgttt catcatttgt attggctaac gggaatcctg cttcgtcatt
      901 ggtgaatttt gaataaggat aatggttaga tacagcaatg aattttgaat aaaatggttg
      961 ttgcagacgt tccaagtatt gtacggattg ttggaaaaat ggtttatcat gcaacccgta
     1021 ttggaacgaa ttgtcatcat taacatcata ataagaagaa tcaaagaaat aatcatatcc
     1081 taaattcttg tatgtctcgt ttcgattcca gaatgtacca gcgttcccat ggaataccgc
     1141 actagtgtaa ccttgtgttt gacttaaaat atcaggtgca gcttggaaag tattttttcc
     1201 gcctaattgt gtgaacaagg agccttgatt caagccaaac aatgaatttt ccatcagcgt
     1261 ttccgcatcg cttgtttttc ctgcttttac ttgatggaaa aagttgtcaa aactgaacgt
     1321 gctgttgctg tggtaaagac tattgatgaa aggtgtaact tcaagctgga gaccattctc
     1381 atctgtcaat ttataatcga tcaggaattg ctggaagctt tctaaatgga tataaatcac
     1441 attttttcct ttagcgagcc cgaacaaatc atcatttggt gctgcataat gttcttttac
     1501 ataattttct acttctttca tatcattggg acttgcttct gcccgcactt ggtttgtctg
     1561 gtaagtttga acaccgtcat aaaccatgaa agcattcaag ccaagatatt tgaccaaata
     1621 atcacgagag aatgttcgag tcagcaattc tggacgatca gcttccgcca taaaaagatt
     1681 tcctgagaaa atcataactg ctaatgtaga gatcgcaaaa gccattcttg ctcggatcgg
     1741 gcgagggtcc aacttgattt tttttgcaat cagcagaaca gtcaagataa taaaatcgat
     1801 ccaatagatc acatcatatg ggcgaaacag tcgaatggca ctttctccca gaccactcgc
     1861 tactttccca gcacctaaaa tcgtgttgat cgtaatgaag tccgtgaatt ctcgataata
     1921 agtgacattc gaaaaaacaa gcaatgtcaa aagaaaataa atgaccatca tcgtgatata
     1981 agcaactcta gggcgtctga tataaagagc aattccaagt aataacaatg tagttgcaat
     2041 agggttgata aacaagataa agtattgaat gccactttcg attccgagat ggaaatcaac
     2101 taaataggca aaaatcgttt tcaaccaaag taaaacaact agtaaagaaa aaaatccgag
     2161 cctcttattc aaaaaggcag gtgtttttat acatttcaag ataatcttcc tttctgcact
     2221 tcttaatcac agaagtgtca tgaaaccatg ttacacagct cacttattct catttatttt
     2281 actagtatga caatatagtg tcaattgaaa ccagaagttt atgctgtttc attaaggttt
     2341 tctttaagct tcatgaaaaa atgagcagta agacaagtcc tatgtttttt gttatacttg
     2401 ggaagagaaa gctaaagcag gtgaaggaat gaaagtaaaa gtaaaaaaaa gagcaagcaa
     2461 tcgattgaaa aaaggatatc cactgatcca aaaagaagac cttgctcatc cccaaaaaga
     2521 aaccacgcaa tgggtggaat tagttgattc gcaaaaccaa tttatcgcaa aaggatatct
     2581 aggaaagcag aataagggaa tcggttgggt attgagccag cagaacatcc catttgatca
     2641 atcttttttt gaagaatttt ttgtgaagtc aaaagaaaaa agaactttct ttttttcaga
     2701 tgattctact accgcttttc gtatattcaa tggagaagga gacgggatcg gcggtctgat
     2761 tgttgattat tatgcaggtt atgctgtttt ttcttggtat aacgaaacgt tatatgcaca
     2821 tcgtgaatta ttgattcaag cttttcgtga aatctacccg gaaatcgtag gaggctatga
     2881 gaaaattcga tttgaatcag taaatctgcc tgagagccag ttcatttacg gaaaagaggc
     2941 accggaaccc ttgatcgtaa aagaaaacgg agtaaaattt gccgtttatt taaatgaagg
     3001 attaatgact gggatctttt tagaccaaaa agaagtacgg ggatcattag cagaaggttt
     3061 cgcttctggg aaaacagttt tgaacatgtt tagttatacc ggcgcctttt ctgttgctgc
     3121 cgcaatggga ggggcaatcg aaacaacaag tgtcgatcta gcaaaacgca gtttaaaaaa
     3181 aacacaggaa cagtttgaag tgaatggttt ggatgtcgat cagcaaaaaa tcattgttat
     3241 ggacgtattc gagtatttca aatacgccaa aagaaaacaa tttttatatg acatgattgt
     3301 attggatcca ccaagttttg ccagaaataa gaaaaaagtc tttcgcgtag caaaagatta
     3361 tggggaactg gtcaaggata gtctggatat tttagcagaa gacgggatac ttattgcgtc
     3421 tacaaatgct gcgaatgtct cgatagaaca attccaaaca atgattgaag aggaattcca
     3481 tgccaaaaat gtttcttttg aacaacttgc tttatatcgt ctgccaaaag atttccagac
     3541 gacggatacc tttttagaag gcaattatct gaaagtgttt gtttatcaaa ttaaaaataa
     3601 ccattagaag gagcgatgca gaatggtttg ggtaaaggga ttgaatatag gaagcggtag
     3661 accaaagatt tgtgcgcctc ttatcggggc cgtccgagag gaagtattac gtgaagcagt
     3721 tcttgcacgt gaagcagggg ccgatttagt cgaatggcga gtcgatcatt atcgtgaagt
     3781 tttttctttt gatgaagtag cagaaacatt ggttcttatc catgagatgc ttgatggact
     3841 gccgttatta tttacgtttc gtaccttagc tgaaggcgga gaacaagaca tatcgatccg
     3901 tcagtatcgc gacctttatg aacatgtgat acacacagga ttagtagata tggtcgatat
     3961 cgagttgttc aaagtagaaa gtctaggaaa aagactgata gaggaaatca agtctttaaa
     4021 cattccttta attatcagta gtcatgattt taaagaaaca ccagcagacc ctgtcttgct
     4081 ttaccgattg aatgttatgg aacattttgg agccgatatc ggaaaactgg cagtaactcc
     4141 caataatgaa cgagatgttt tgcggttgat ggagttgact agacgggcaa atgcttttgt
     4201 ctccatgcct attattacga tgtccatggg aaatcttggt aaaatttctc gtctggctgg
     4261 cggaacgacg ggttccgtta tgacatttgg ttccttaagc agcgattcta cttctgctcc
     4321 aggacaatta ccggtcaaag cattgaagca aattattcaa ttattaaatg aaccgttgta
     4381 gaacaagttt gaggtgatat tttttggcaa agaaaaaaat agtaaaaacg aatgcaatcc
     4441 gtatggtcga acaaaaaaag attccctata cagagcacga atatgagtgg gacgaaagcc
     4501 acctaagtgc gtcatcggtc gctgaacagc ttccagaaag ccaatctcat atatttaaaa
     4561 cactggttgc tgtgggcaat gtgacggggc ctcttgttgc tgtgataccg ggagaagccg
     4621 aattgaatct aaaaaaatta gcaaaagttt cagggaataa aaaagtagaa atgctccatt
     4681 taaaagattt ggaagcaacg accggataca tacgtggtgg ctgctcgcct ataggtatga
     4741 aaaaactatt tcctacttat ttagatcaaa ttgcagaaag ctatgaacaa atcattgtct
     4801 cggctggcag aagagggcta cagatggagt tagcacctca agatatctgt gcattaacga
     4861 gcggacaatt tgcagatata aaacaataaa tcatacgtat aaaagaaaga aggaggccgg
     4921 gatgttgttt gtccagtctc cttctttctt ttttatacat tatgctcttt gcccggcatt
     4981 cattcctgct acatgccctg tagcgaaagc cgctgtgata ttaaagccgc cagtataacc
     5041 attgacatcc agtaattctc ccgcaaaata cagaccatca atgattttac tctccaatgt
     5101 tttaggataa atttccttta gagaaacccc tccgccagtt acaaatgatt tctcaatagg
     5161 aaaagttttg ttgattgata gcttaaactc tttgcatagt tgaacaaaat cttgaatttg
     5221 tttttgagag gcttgttgtc ctgtcagatg atccatttca agccgctcaa gaaagaaaac
     5281 taacaatcgc tcaggcaata taccatgcca agcattgacc aagttctttt tggttgcttt
     5341 acttttttct gtcaatatat gaataagctc ttgtttggtt tgtgtaggga aacaatccag
     5401 agaaagtgtc actggttctc ccgttttctc taattcttta ttgacaaaac ttgaacaacg
     5461 cagtgcagcc ggaccagaaa taccgaaatg ggtgaaaagt aaatccatcg tatgttcagt
     5521 caatacacga ccttttttat ttaaaacgcg taaagtgatg tcttgtaaag aaagcccttg
     5581 aagtgttttc tcctgaatat acggttcatc cgatatcaag ggggactctg tcgcataaag
     5641 aggcgtcacc gtgtgaccca ctcgcttcac gatcttgtac ccatctccag tagaaccagt
     5701 agatggataa gtccgtccac cagttgttaa gataatggca ggagcatgga actcttcgaa
     5761 ttccgtgcgt ataccgtaaa ttttatgttc tttgtggatc aatttctcta ctcgagtaga
     5821 gaatagaagc gtcacatcta gttctttcag acgattgagc aatgcttcga taatcgtttt
     5881 tgatttattt gttacaggaa acatccgtcc atgatcctct tcttttaaat gtacgccttg
     5941 tgattcaaag aagttcatga tatcgaaatt attccattgc gcaaacgtac tatataaaaa
     6001 ctttccattt ccaggaatat gtgcaatcaa atcatcaaca ggacgattgt tcgtaacatt
     6061 gcaccgacca ccacctgtca tcagtagttt ttttcctgct tttttgtttt tttcgatcaa
     6121 gagtacgcgt gcgccttgtt cagctgcact gatcgctgcc atcatcccgc ttgttccagc
     6181 gccgactacg atcacatcat acagtttttc cattccctca cctcaaggaa agtgtagcat
     6241 atctgaagaa agaaaacaga aaaaatgttt tgagccaaaa gagaaaatga gctaaaatga
     6301 gggaagataa gcaaaggagc gtggaacgat gacaaacgca acagaatatg ttcaagcaat
     6361 tcaagaaaag ctacatcaaa aggatcaagg gcaagaagaa tttttacaag caatcgatga
     6421 attcatgccc acggttatgt cttttttgga cactcatccc gaatatatcg aaaagaatat
     6481 cttagaactt ttaacggaac cagaaagagt tattcaattt cgagtgcctt ggcaagatga
     6541 tgaaggaaac tggcgagtaa atagagggta ccgtatccaa tacaactcag ctatcggccc
     6601 ttataaaggt ggattgcgct tccatcctag tgtcaatcta agtatcttga aatttttggc
     6661 ttttgaacag attttcaaga atagtttaac cggtctgcca atcggtggag gaaaaggcgg
     6721 aagtgacttc gatcctaaag gaaaatctga taatgagatc atgcgttttt gtcaaagttt
     6781 catgctggaa ttgtcaaaac atatcggccc atcgattgat gttcctgcgg gagatatcgg
     6841 tgtaggagct agagaaatcg gctatttgtt cggcgaatat aaacgattga aaaaatatga
     6901 tactggtgtg ttgacaggta aacctttgga tttttgggga agtaagatac gtacggaagc
     6961 tactggttat ggattagtgt attatgtcaa acatctattg aacgaagaaa aagattcatt
     7021 taatcaaaaa acagtttttg tttccggaag cgggaatgta gccatttatg caatcgaaaa
     7081 agtgcaagag ctaggcggga aagttgttac atgttcagat tctagcgggt acatctatga
     7141 tccagaagga atagatgtga aactattgaa agaagtcaaa gaaatcaata gacaacgttt
     7201 gacggaatac gcaaaccaac gtccttctgc tatttatcat gctggagaat ctgtttggac
     7261 attgaaagaa aaagcggata tcgctttgcc atgtgctact caaaatgaaa tagacgaaag
     7321 cttggccgaa atcttagtag aaaatgggat caaaatcgta gcagaaggcg ctaatatgcc
     7381 atgtacagta aaagctgttt ctgttcttca tgaagcaggc gtgtggtatt gtccaggaaa
     7441 agctgctaat gctggaggag tagcagtatc tgctttagaa atgagtcaga acgcccagcg
     7501 attgacttgg gaaagagagc aagtggatga gcagctggat caaatcatgg aaacgattta
     7561 ccatacgtgt cgccaaacag cagccgagta cggcgacgaa aaaaatctgc ttcttggagc
     7621 aaatgttgct ggatttgaaa aagttgccaa agcaatggca gcagaaggtt tagtttgaaa
     7681 aatgaaactt tcttggaaat attgtcagca ttttgtttat ttgcttgaaa aataataaaa
     7741 aaaaacgtaa agtattacct gtagagtaaa cctataagga ggagaacaaa tggcacacat
     7801 tcattttgac tattcaaaag tagcaccgtt tgtcaacgaa caagagttag ggtacatgca
     7861 aagccaagta acagcagccc acaacgaatt acgggaaggt actggcgcag gaagcgactt
     7921 ccgcggctgg atcgatttac caacgaacta tgacaaagaa gaatttgcac gtatcaaaga
     7981 agcagctaaa aaaatccaat ctgattctga agtattagtt gttatcggta tcggtggttc
     8041 ttatttaggc gctcgtgcag cgatcgactt cttgaatcac acattcttca atttattaga
     8101 tagcaacaca agaaaagcac cacaaatctt ctttgccgga aattcaatca gctcaacata
     8161 tattgctgac ttgatcgaag taatcggtga tcgcgacttt tcagtaaacg ttatttcaaa
     8221 atctggaaca actactgaac cagcgattgc gttccgtgta ttcaaagagc ttcttgttaa
     8281 gaaatatgga caagaagaag caaacaaacg tatctacgct acaacagata aagcaaaagg
     8341 tgcagttaaa gtagaagcag atgcagaagg ttgggaaact ttcgtgattc ctgatgacat
     8401 cggcggacgt ttctctgtat taactgctgt tggtttgtta ccaatcgctg ttagtggtgc
     8461 agatatcgat gcattgatgc aaggtgccgc tgatgcaagc aaagcatact caagcgacaa
     8521 actagaagaa aacgaagctt accaatacgc agcaatgcgc aacattcttt accgtaaagg
     8581 caaagtaact gagttgttga tcaactatga accaggaatg caatacttct cagaatggtg
     8641 gaaacaattg tatggtgaat ctgaaggaaa agaccaaaaa ggcatctatc cttcaagcgc
     8701 aaacttctca actgatttgc actctttagg acaattcatc caagaaggac gtcgcaatat
     8761 ttttgaaaca gttgtgaagg ttgaaaaacc tcgtaaatca atcacaattc ctgaacaagc
     8821 agaagattta gacggtctag gctacttgca aggaaaagaa gtggacttcg taaatacaaa
     8881 agcatttgaa ggaacattgc ttgctcatac agacggtgac gtgcctaact tgctagtcaa
     8941 aattccagaa atggatgctt atacattggg ttatacaatg tacttctttg aaattgctgt
     9001 aggtatttca ggttacttga atggaatcaa cccattcgac caaccaggtg tagaagctta
     9061 caagaaaaac atgttcgcac ttctaggcaa accgggcttt gaagatcttg ctaaagaatt
     9121 gaacgaacgc ctgtaagata agggtttttc gctagattta aataatcagt gatagaaaca
     9181 tgttcgcttt aaaatgaaaa ctggtaccca tttaggtact caaacatact gcatcgttta
     9241 ttcagaataa ggggctgtga caagacgttt gtcacagtcc cttgtttgta tagaaatcga
     9301 ttgattgcct tgctctttag tttgttttag gactttaaga acagtgaggc tgacttcgaa
     9361 ggttaattct gtttttttgt tttctagaat cagtaagcaa aaaagcactc acttcgagtg
     9421 cttttttgcg atatattctt agcttaagat aggcctaatt tttcttttac agatgagggt
     9481 accttatcgc tggtaattac ttttttctct atgatccgct tttcgcttgc tttcaactgc
     9541 aagatcgttc cttcggtgta agcagaacca ttggcagagt caccagaagt aatgacatcg
     9601 aaatctaact gtcttttttc accgttttca gcataagcat ctacgttgta tttaaaacct
     9661 cttccaatta cttccccatt atctgctttg atatcagttt ctgcaggcat tggagctttg
     9721 actaccgcat aataatcttt acctacataa gtagactgat agtagtccca acctttccat
     9781 cctataaaag caatcaatat gataacgatc aaccctaaaa tttttttcat gaaagatctc
     9841 cttttttatt tttattatat taaatattat acagataata acggaatatt atcatcgaaa
     9901 cagctaacaa aattgtcata aaaaacgaga tggttgatat tagaacttgt gtttttgttt
     9961 aggtctagag ataaagagag acaatttcca aatatatgta atgaatacaa aaagacgttt
    10021 gtcgcggatt accgttacaa acgtctttta ttgattttcc gagatctcat cagtcgccat
    10081 ttggaatggt tcactcctta tctagattcg tttaatgctc ggactgcttg ttcgattgta
    10141 ataccaaacg caacgttatt ttcgttttgt gcatcaatcg ccataaaacg gttagaagtt
    10201 gtatcaaaag ctacgcggta ttgcatattt gtttttgtaa acgtcataaa attcatctcc
    10261 tttgtaatgt aatttagttc ttgaaagttt cctttaaact ttcgaactta taccaagttt
    10321 agcatcgtac gttttttgat gcaattaaaa agcatttatc attttcctta tttatttttt
    10381 cttaaatggt ttagctattt tcttttaatc cgataagtag cccaatcatc aaggttacaa
    10441 atactattgc ttgaatataa atcatatgct cacctcttta taaataactt agcaatataa
    10501 agaaaaaaac gcacgaacaa cataggaata taaacaaacg tttttgtcac aacgtctaag
    10561 atcgtgttaa aaaatagtta tctaaaaagc agaaagatac tcaaaataaa aaataaaaaa
    10621 atgaataaaa acgttttcaa atacaaggta atttgttatt ataaaataaa gaaaaaacaa
    10681 aataaaaata aagaaaagag ggaatgaaat ggtaaaagca gaagtaggaa gatcttatat
    10741 atgcaaaccg atcggagtat ctcatgaact aatcggctgt attgaacgta catatatcaa
    10801 cacggctgtc gtgtatgttg aaagttatga ccaacgagac tatcaactta tcaatgaaag
    10861 caagtatcgc atgctcgtaa aattctgtga tattagcgca cctactgaat tggtttctta
    10921 aacagtattt ttgagaattc gcaagaactc ccttataata taaataaaga cagaagggag
    10981 cgagaagata tgccaaaaag aaaaagttca gggaaaatgg gaattattct tgcagtgatc
    11041 tctgcaattc ctgctatttt agctattgtt cgtgcgatga aggaatcaag agaaagttaa
    11101 gcacacatta tgagcgtcaa acaaaaaacg catatacctg cggtggcagg ttatgcgttt
    11161 tttgttgtat aaagactttt ttcattaacg atttttgatt agccgactcc caaaacaaaa
    11221 tttagcagtt tatctgaata agtgatttct tcatctgttt gtttcacact ttcatttagt
    11281 agtcccatct catcggttat gataccatcc acaccataaa acatcatgcg actcatggca
    11341 tctgaatcgt tgattgtcca tacatatact tcttttccgt cttggtgggc agaattaatg
    11401 aagttacggt tgatcgtact atattccatt gtcagaaaat cagcaggcgt cacagggggc
    11461 ccaacaatat tgaaaggtaa gatgtagccc acataaaagt ttggttctgc ttcttttaaa
    11521 tctgaaacgg tttggtacgt caaactttgc aaaatatgat ggttctctaa gataactttg
    11581 cggtatttat ggacaaatcg ttcgacaagg tcatccgaat cttttttaga ggtcttgatc
    11641 tcaataagta atttttggtt tagcttatgt gctttttcca aataagaatc aaaagaacaa
    11701 acaggggctt gcactccgtt ttcagtaact gtaagatttg tcaattcttt caatgtaaga
    11761 tcctgtggtg ttccatttac ccctgttaag tgacgaagat ttgcatcatg catcactacg
    11821 aaatgaccat cttttgtttc ctgaacatcc atctctacat aatcaggatg atagtctctg
    11881 cttgtttttt caagtgcttc taaagtattt tgcgccccat tttgggtact cacacctctg
    11941 tgagagacag tcactggttt tgtctgaaca gctgaagtca gataatccat attgtaaaga
    12001 cagacgccaa taccgaaaaa aactgcaaaa agagtcaaac cagtgttttt cagcgcagag
    12061 aaacgcaagt tgggggcttg tgggataaac cacttaggga tctcaggcaa gaagccttcg
    12121 tcatccatga aatcaacaat gatataaaaa atccctacgg tagacatcac gatattgaat
    12181 aataaaatcc cttgtaaaag cgtcatagca aacacagcgc tgatcaatgc atagtctggg
    12241 aaaaattgtt caaccatact ttgtgccaaa ataacaacga tatatcctaa agaagaaagg
    12301 agtaaaatcg taccgccaat cacaataaat tggcccgtga tggccaaaag acgcgatttg
    12361 gtcaatgacc agctttcccg aatggctgct cgaaaagaac gatctcgtag aatcatttcc
    12421 ggtaaagcaa aaatcagtcg aatcccaata tagccaagga aaatataaac gagtaaaaag
    12481 gaactgacga tgatccaacg attagcaaaa ataaaatcca taatgaaagc ggggattttt
    12541 atttttgaca gtagatcaga attaaaactt aatccgctga tcggtagaat caataaaaaa
    12601 taagcaagga aaaacaaaaa agtaatgggt ctcactttct tcagctgaag tatcgtcaag
    12661 tgtaagagtt gcttcaaaga gattggttct ttctttttaa taaaaaaaac actcatcaaa
    12721 agaaaagtaa attcgaaata aactaacagt aaaatcgtca tcaaaactac gattaacgag
    12781 agtagaaccc caggatgttg agaaaaaatt gaaggaatat tgtcataaga caaatagtca
    12841 attgcccctc ggtgtaaaat aaaacgggtc gtactgctca ataagggtaa acaaataaat
    12901 aaaataaagc catgcatcag caagacatca cggaaataag cttgtgttcc ttttaaaaag
    12961 tcccaagcat tacctaagct acgtttcaaa taattcatcc tatcacctgc tcttcacatt
    13021 gtagcgcaaa tctaatgaaa aaggaaaggg tgcagtgtgt tttgcagacc ctttcccaga
    13081 tt
//
LOCUS       DAFLWQ010000080        12988 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.083, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000080 DAFLWQ010000000
VERSION     DAFLWQ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12988
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.083"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(204..1652)
                     /gene="cls"
                     /locus_tag="L1V16_002276"
     CDS             complement(204..1652)
                     /gene="cls"
                     /locus_tag="L1V16_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBN1276599.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGEIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            complement(1804..2697)
                     /locus_tag="L1V16_002277"
     CDS             complement(1804..2697)
                     /locus_tag="L1V16_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1276600.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="L1V16_002278"
     CDS             complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="L1V16_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBN1276601.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(3472..4573)
                     /gene="prfB"
                     /locus_tag="L1V16_002279"
     CDS             complement(join(3472..4500,4502..4573))
                     /gene="prfB"
                     /locus_tag="L1V16_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBN1276602.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(4699..7233)
                     /gene="secA"
                     /locus_tag="L1V16_002280"
     CDS             complement(4699..7233)
                     /gene="secA"
                     /locus_tag="L1V16_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBN1276603.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            complement(7455..8006)
                     /gene="raiA"
                     /locus_tag="L1V16_002281"
     CDS             complement(7455..8006)
                     /gene="raiA"
                     /locus_tag="L1V16_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBN1276604.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            complement(8134..8853)
                     /locus_tag="L1V16_002282"
     CDS             complement(8134..8853)
                     /locus_tag="L1V16_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBN1276605.1"
                     /translation="MRCSCCGKDIIQNLTFSEIIGVSKSRLPQTCSVCRAQFHLLEAK
                     GCAGCQKPIHLKYEETKKKANTSFVYCNDCQEWKKKYPAYDFQHRAFFTYDEKMQAWI
                     NRYKFMGDIRLAGTFAYKWTQIKKDYPAYIYCPIPLSEKRWLERGFNQVSEMLKAAKI
                     PFQMLLKREQHLLAQAKNTRKERLEMPQPFELAVPLSKIQHKKILIIDDVYTTGQTLF
                     HAADCLQNAQPKIIRTISLAR"
     gene            complement(8850..9926)
                     /locus_tag="L1V16_002283"
     CDS             complement(8850..9926)
                     /locus_tag="L1V16_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBN1276606.1"
                     /translation="MFDQPEAKPREVVFFWTGQLTEKQTEIAKRILCHSEKRHHLIWA
                     VTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNELFLRYRYVFPEEKITLLHGNTA
                     TAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYNGDAGLAHAVQTAIRSNGRFIY
                     LSATPDEKLLKEIKQTFELHKLALRFHRRLLPEPVLVFMNNWRQKCGNKKKINSLVRI
                     IQQLIKENRILLFCPSITMMHRLKITLQEAFPEYEITDVSSQDDQRAKKVQKMREAIY
                     EILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQIAGRADRKGPYTNSRVYFFYE
                     EKTSAIRKACQEIKEMNEEGKQML"
     gene            complement(10244..10564)
                     /locus_tag="L1V16_002284"
     CDS             complement(10244..10564)
                     /locus_tag="L1V16_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1276607.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIA
                     LIGE"
     gene            complement(10672..10959)
                     /locus_tag="L1V16_002285"
     CDS             complement(10672..10959)
                     /locus_tag="L1V16_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276608.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            11086..11730
                     /locus_tag="L1V16_002286"
     CDS             11086..11730
                     /locus_tag="L1V16_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBN1276609.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKNFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSANHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            complement(11789..12496)
                     /locus_tag="L1V16_002287"
     CDS             complement(11789..12496)
                     /locus_tag="L1V16_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1276610.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRRDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(12716..12886)
                     /locus_tag="L1V16_002288"
     CDS             complement(12716..12886)
                     /locus_tag="L1V16_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276611.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
BASE COUNT         3590 a         2812 c         2259 g         4327 t
ORIGIN      
        1 gctatactgg ctttgaaatg tgtctctttt aatagcatat attagcttat ttcttgcttt
       61 ccccaaaaaa caagagatac cccaaagtta atttcgctca tgcgagacgc tttctccatt
      121 tctgacgtac tctcagaaat ggccccgtta aaaaaggaca cgagatctcc atctgttgat
      181 ggttctcatg tcctttttat gttttaaagg agcggcgaaa tcaatcttgc taatccttct
      241 ttcatcttga tgattattcc tcggttttca tacatttctt ttgtgagatg cgtagaaatt
      301 ttcgagtctt caaaaaaagc ttttcttaca cgtgaagcca ttcgttcatc ataaaccagt
      361 gtattgacct caaagtccaa gcgaaatgaa cgaacatcga tatttgctga gccaactgaa
      421 acaatgccac catcgataat catcgtcttt gcatgaataa atccattctc atatgtttcg
      481 atccttgctc catactcgat cagctctgca gcgaaagaat acgttgccca gtaaacgaga
      541 agatgatctg gtttgttagg tatttggata tgaactttta cgcctgaaag aagagccaac
      601 ttcagtgctt catgaatcga tccatccggt atgtaataag gcgtttggat caatatctcc
      661 cgtttggcta acgaaatcat tttcaaataa gtcattttga tttgttcatg ttcggtatct
      721 ggtccgcttg tcacgatttg aacagctata tcaccagtag tgtgaatgga cggaaaaaat
      781 ttgggagaat agcctacttc ttttgtatgc tgagaattcc agtccatcaa aaaacggttt
      841 tgcaaggtat acaccgcttc tccgtaaata cgcaaatgat tgtctcgcca ataaccaaat
      901 ttctttacca atcctagata ttcatttcca acattgaacc cacctgtata tccgatttcc
      961 ccatcaataa ctacgatttt acgatgattg cgataattga tccgaggatt aatatacgga
     1021 acaaatagag gaaagaaaaa tgcgacttct ccgcctgctt ttttcaaatt ctgaaaaaag
     1081 ctggaagaaa cttgtgtgga accccatgca tcaagaagga ctctgacttt tacccctcgt
     1141 cttgccgcct ctgtcaatgc atctcgaact tcttcaccta atgcatcact gcgataaata
     1201 taatactgga agtggatatg gtcttctgcc tgcttgatat cttcaatcag cgcatcgaat
     1261 ttttcacgac catctgtaaa taaagtgatt tcatttttag tcgtatagag cgtactttca
     1321 aataccgtga gcatatagat caattgtttc acatctactt gtccagtagg cggatgagga
     1381 taaagccctc gcatcaatgc ctgtttgtct tcttcaattt ccaggttctt accgattttc
     1441 ccttggatct tcaaatcaaa gattttctct ttggaaatcc ctcttcctaa aaaaatatat
     1501 aaaataaatc ctacaactgg aatgaacatc aaaacgagca gccatgccca tgtttgagca
     1561 gtttcctttc tttctcgaaa aacgatgata aaggaaagca aaatattcat aatcaaaagg
     1621 atcgtaaaaa aattgtcaac gataattttc acggcttcac ctcttcttct accaacttaa
     1681 gaatacccaa gttgtttttt aaagtaaagg gaaaaaagcc gcttccttct attctcctag
     1741 ccaataaaaa aagaaagctg gaacgaaact gtccaacttt ctcattttat ttatattgtg
     1801 gtattagaat ttcaagaaac gtctcataga aatgatcgag ccaagtgaac caatgatcac
     1861 accaatgccg accattaaaa gattgatttt ccaaacgata ttttgtggat gaatcaatga
     1921 ataatgggaa cgtaataatg atggattgat caattggaaa aaccatgcat aaccaaatgt
     1981 gatgatcaaa attggaagaa ttgcaccgat cagaccgatc cagccacctt caaggaaaaa
     2041 cggccagcga atatatccat tttttgcacc gactaaacgc atgatttgaa tttcacgctg
     2101 tctagacaaa atcgtgatcc gaatcgtgtt cgaaatgaga aacatcgcta cgaacagcag
     2161 caatgccgct gcaactaatc cccatgtccg aactgcacca gcgatttgga aaatccgatc
     2221 tgaggaagct ccaccgtaat cagaacgaga aacattcttc aaatctgctg cttcttctgc
     2281 tacttgtttt gtataagaag gatcagtagc acttactaca tacacatcat ataacgggtt
     2341 attgtcacct tcaaacaatt tccaggaatc acccatttcg ttttggattt ttttcaattc
     2401 ctgttctttg cttgaaaatt caactttttt aacatgatct aagtcattca attctttttc
     2461 tagctttttc atctcttcgt cttttgtacc gatatctacg aatacagata catcaacgtt
     2521 tccttctata tcctgagcta atttagttgc attcatgata actgccatga atacaccgac
     2581 taaagtcaac gtgatcgtta ccgcactgac tgaagcaact gtcatccagc cgttacgttt
     2641 caaactcttg atactttcta ataaatggcg gaaaaaggtt ctaatcatcg tatccatatt
     2701 ccccttccgc ttgatctcga ataatgcggc cgttttcgat agcaattact cggtgccgaa
     2761 tcgtatttac gatcgtactg ttatgtgtag ccatcacgac agtagttcct tgggcattga
     2821 tccgatctaa taatttcatg atttcccatg agttttctgg atccagattt cctgtcggtt
     2881 catccgcgat aagtacttta ggcgtattca cgattgcccg agcaatagag acacgttgct
     2941 gttccccacc ggataattcg ctaggaaaga ctcgaacttt gtgtttcaaa ccaacaaggt
     3001 ccagcacttc cattactcgt tttttgatat ctcgaggttt tctgccgata acttgcatag
     3061 cgtacgcaac attttcatat actgtttttc ttggtaataa tttatagtct tggaacacca
     3121 cgccgatttc tctgcgtaga taaggaactt cgcggttttt gattgctatt agatcatgac
     3181 ctgcgacgtt caaagttcct tttgaagctt tttcttctcg atacatcaat ttgatgaatg
     3241 tagatttacc ggctccagac ggaccaacca catagacaaa ctctccttgt tcgatgacaa
     3301 tcgagagatt gcggatagcg gtcgtaccat ttgagtactt cttcattaca tccttcattt
     3361 caatcatggc gttctctcca tatctttttc agtctttagc tattatagca tggcaatgtt
     3421 tcaacatgct tgcaaaatct tacaatttta tttcaattta acaatgggtt cttattgtag
     3481 atgcattttt aaatagccgt caataaataa atcaaggtca ccgtccataa ctgcttggac
     3541 atttcctgtc tctacgtttg tccgatggtc ttttaccata gaatagggat ggaaaacata
     3601 agaacggatc tgtgaacccc agccgatttc tttttgttct cctcgaagtg cagctgcttc
     3661 ttgttctttc ttttccactt ctaattgata aagcttagct tttaacatcc ccatcgcttg
     3721 ctcacggttt ttcaattgtg agcgttgtgc ctgactagct actactgttc ctgtaggcaa
     3781 gtgagtgatc cgtacagcag attctgtttt attgatgtgc tgaccacctg caccacttgc
     3841 tcggtacgta tcgattttca aatcatctgg attgatttct atatcgatcg tttcatcaag
     3901 ctctggcatc acatctaccg aacaaaaaga agtatgacgt cgtttcgctg agtcaaaagg
     3961 cgaaatccgt acaaggcgat gaacaccttt ttctgatttt agataaccaa aagcgttatg
     4021 tcctttaatc agcagggtca cactcttgat ccctgcttca tcacctgctt gataatctag
     4081 tgtttctact tgatagccat gctgctctgc ccaacgtgta tacatacgta aaagcatgct
     4141 gccccagtct tgggactccg ttccgccagc ccctggatgc aattcgacga tcgcattgtt
     4201 tcgatcataa ggtccgtcta acagcataga taattcatac gtcttcattt tttcatctaa
     4261 tgcattgata cgtgtttctg cttcttcttg cattgctgca tcaggttctt cttgcagcat
     4321 ctccaccatc aattcgattt cttctagttc ttcggcaaga gaatggaatt ggtcataggt
     4381 ttctttatta gcgttatttt cgctgatcac tttttgtgcg gcttcgctgt catcccaaaa
     4441 accaggttca gccatttttg cttctgcttc cgcgatgtct tcttccagct gatctaagtc
     4501 aaagagacct cctgaaactt gtgacctttt cctgcatttc tgtcaggaga tttcgaattt
     4561 cggatatttc catgtttttt ccttctttca ctatactttt ttcattatat ctagtctaac
     4621 agaatcagca aataacagaa agaaggtgag acgaattctt aaaaaaagaa tttgtctcac
     4681 caatcctgct gtcagaaatt agtttgcatt ttttccatga cagttcttat attttttccc
     4741 gcttccacaa ggacaaggat catttcttcc gaccttattc acatggattg gctgtttttt
     4801 cgcgctagta ttactatttt ctttggcatc tccgtcttct gagtgagaag ctgttccttg
     4861 agaaacctgt tcacgctgta cgttttgacg gatctcagct ttcataaaga ttcgagtgac
     4921 ttcatactcg atggcgccta ccatatcttc aaacatctta tagccttctg tttgatattc
     4981 gactaatgga ttgttctgtc cataagcacg taagccgatt gactgacgta attgatccat
     5041 tgcatcaata tggtctgtcc atttagagtc cacaacacgc aagatcacga ctttttcaaa
     5101 ttccaacagt tgctctggac catttagttg agccgctttg gtattaaata cttcttgtgc
     5161 tcgttcgttt agatactctt tgatctcctg agctgttttt ccttcgatat ctgcaagagt
     5221 aatgctatct tcatggacaa gagtactgcc ggcaaaatcg atgatacttt ccaaattcca
     5281 attttctttc tctaattgtg tatgcgcatc tactacacga ctgattgtcc gtttgaccat
     5341 gttcattagt ggcttggata agcttttttc ttccatgatt acttcttgtc gctgtttata
     5401 gattacttca cgttgttcac gcatcacatc atcgtattgt aagacgtttt tacgtgtgtc
     5461 atagttattt ccttctacac gtttttgtgc agattctact tgtttcgtca gcatcttgct
     5521 ttggataaca gcatcttcct caccgatctt catccgatct aagaaagctt tgattcgttc
     5581 tgaaccgaat cgtttcatca aatcatcttc caatgacaag tagaactgtg acataccagg
     5641 gtctccttga cgtcctgcac gtcctcgaag ctggttatcg atacgacgag attcatgtcg
     5701 ttctgtcccg ataactgcta gaccaccaag ttctcttacc ccaagtccta acttgatatc
     5761 tgttccccga ccagccatgt tggtagcaat cgtcacagca cctttttgac cagcattcat
     5821 gatgatctct gcttctttaa agtgattttt cgcattcagc acttcatgag gaatacgttc
     5881 ttgattcagc atatctgata ataactcaga tgtttcaacc gcaacagttc cgactaacac
     5941 aggttgacct ttgcggtagc gatctttgat atcttgcacg acagcgtgga acttgctttg
     6001 taatgttggg taaagcaaat ctggacgatc atcacggata accggacgat ttgtcggaat
     6061 ctggtatact tggatgttat aaatttctct gaattcttct tcttctgttt tagctgtacc
     6121 agtcattccc gcaagtttct tgtacatacg gaaatagttc tggaaagtga tcgtcgccat
     6181 ggttttcgtt tcgtcttcga tctctacgcc ttctttagct tcgattgctt ggtgaagtcc
     6241 atctgaataa cggcgtccat ccatgatccg accagtgaac tggtcaacaa tcagtacttt
     6301 tccgtcttgg acaacataat cgatatctaa aagcatgata tagttggctc tcaatgcttg
     6361 atccaagtga tgggtcaatg cagtattttc aatgtcgtat aagttatcca aaccgaatgt
     6421 ttcttctgct ttttcgatcc ctgcttcggt taaactgatt gtttttgatt gtacatcgat
     6481 tttataatct tcttcttctt tcaaacgttt cacgaagttg tctgctcttg tatataaagc
     6541 tgtggatttt tctgcttgcc ctgaaatgat cagcggcgtt ctcgcttcat caatcaagat
     6601 tgagtcaact tcatcgacaa tggcataatt cagcggacgt tgtaccattt gatggcggta
     6661 aacgaccata ttgtctctca agtagtcaaa tcctaattca ttattcgtac tataagtgat
     6721 atcacaatta taagcctcgc gtttttcatc cgaagatttt gagttgatat tcaaccccac
     6781 tgttaatcct aagaaattat aaagttcgcc catttccgtc gagtcacggg ttgctaaata
     6841 ttcattgacg gtaactacgt gtaccccttc gccagtcaga gcatttagat atactggcat
     6901 cgttgcggtc aaggttttac cttcaccagt acgcatttca gggatatttc catcgtgaag
     6961 cacgattcca cccatcaatt gtacgtggta tggatataaa cctaatacac gttttgctgc
     7021 ttctcggacg actgcaaaag cttccggaag taattgatct aatgtttctc ctttttggta
     7081 tctgcccttg aattcagcag tttttgcctg taattgttca tcagttaatg ctgccatttg
     7141 gtcagcgtat gcttcaactt tttttgcaat gctatctaaa cgttttagtt ctttcttatc
     7201 gttttcgata agtgaacgaa tcaaattggc catgcgttgt gtaatctcct tttccttctg
     7261 tgtattatcc agactatgta gactttactt ttcattttat cattagttat agataattga
     7321 aatatcttaa gcgtattaaa gtaagaactt cataatttat tcatatttca tctaaaagag
     7381 gaggaaactc aaaaaaactt gcggcagctg tcagtagctg ctgcaagttt tcgttgttat
     7441 ttaagtaagg ctgatcagtc tgtttcaatc agtccgtatt ttccatcttt acggcggtaa
     7501 acgatacttg taccatttgt ttctgcatct tcaaaaataa agaagttatg tcccagcatg
     7561 ttcatttgta agactgcttc ttcactatcc attggtttca atgaaaggcg tttcgtacgt
     7621 acgatatcta attcagaatc attttcgttt tcgtcctctt cattgaataa agcagcagca
     7681 tctgcagtat tcatgcccgt ttcacgggat ttacgattaa tttttgtttt gaatttgcgg
     7741 atttggcgtt ccaatttgtc aacaaccaaa tcgatacttg cgtataaatc tggagaagtt
     7801 tcttcggcac gtaatacaag ataaggtaat gggatcgtta cttccacttt tgctgttttt
     7861 tctgtataaa cttttaagtt cacatgcgcc gttgcatcgg gtgcgtcact gaaatagcgt
     7921 tctagtttgc ctactttttt ctcaacgtag tcgcgaatcg cttcagttac ttcgatattt
     7981 tcgccgcgta cattatatct aaacataaaa attacccctt tcgtctacca caatcaagaa
     8041 ggagaaggac cactctttcc ctcttcttaa ttctattata tcgaactcta ggttatttgc
     8101 aaattaaatc gctatcaaat ttccacatct gattcatctt gccaaagaaa tggttcggat
     8161 gattttcggc tgtgcgttct gcaagcaatc tgctgcatga aaaagcgtct gtcctgttgt
     8221 atagacatcg tcaataatca atattttttt atgttgtatc ttagaaagag gtacggcaag
     8281 ctcaaaaggc tgaggcatct ccaatctttc ctttcgcgtg ttttttgctt gagcaagcag
     8341 atgttgctct cttttgagca gcatctgaaa aggaattttt gctgctttca acatctcgct
     8401 tacttgattg aatcctcttt ctagccacct tttttcagat aaaggtattg gacaataaat
     8461 atatgccggg taatcttttt ttatctgagt ccatttatat gcaaaagtcc ctgctaatcg
     8521 gatatctccc ataaacttgt accgattgat ccaagcctgc atcttttcat cgtacgtaaa
     8581 aaaggcgcgg tgttgaaaat catatgcagg atatttcttc ttccattctt gacagtcgtt
     8641 gcagtaaacg aaactagtat ttgctttctt tttcgtctcc tcgtatttca aatggattgg
     8701 tttttgacaa cctgcacaac cttttgcttc taataaatgg aattgtgcgc ggcaaactga
     8761 acatgtctga ggaagtctag atttcgacac tccgatgatc tcgctgaatg ttaaattttg
     8821 aatgatgtct ttaccgcagc aactacatct cacagcatct gcttcccttc ttcgttcatt
     8881 tctttgattt cctgacaggc ttttcgaata gctgaagttt tttcttcata gaaaaaatag
     8941 actcgactgt tcgtataagg acctttacga tcagctcttc ctgcgatttg caccaaagag
     9001 gatttagtaa aaactggatg atctgctcct aaaacgatga cagagattct ttcaaatgtg
     9061 actcctcttt ctaggatcat tgtggttaac agtatctcgt atattgcttc tcgcattttc
     9121 tgaactttct ttgcccgttg atcgtcttgt gaagaaacat ctgttatctc atattctgga
     9181 aaagcttctt gcagtgtgat ttttaaacga tgcatcatcg taatacttgg acaaaataaa
     9241 aggatacggt tttctttgat tagttgctga atgatccgca ccaaagagtt gattttcttt
     9301 ttgtttccac atttttgtcg ccaattattc atgaaaacaa gcacgggttc aggaagcaag
     9361 cgccgatgaa agcgcaaggc aagtttgtgg agctcaaatg tctgcttgat ttcctttagt
     9421 aacttctcat caggcgtggc acttaagtag atgaatcggc cgtttgatct gattgctgtt
     9481 tgcacagcgt gagctagccc agcatccccg ttataaggaa acgcatcgat ctcatcgatc
     9541 actattaaat caaaggaccg ataaaaacgg tatagctgat gaatcgtaca gataacaaaa
     9601 gaagtaaagg tataagccgt tgctgtattc ccatggagca acgtgatttt ttcttctgga
     9661 aaaacataac gatagcgtaa aaacaattca ttacaaacat cgactcgcgg tgtacaaatc
     9721 gctactcttc ctccagcttt taaagtttcc actaaaatag gataaagcat ctctgttttc
     9781 cctgcacctg ttacagccca aataagatga tgtctttttt ctgaatggca aagtattctc
     9841 tttgcgattt ccgtttgttt ttcagtaagc tgtcctgtcc aaaaaaagac gacttctcga
     9901 ggttttgctt caggctgatc aaacaaatat aaatcttgtt gagtgtcgca tcaccctaaa
     9961 tatagacaat gtgtacaaaa ataaccgtaa tctgcaagct gtccaacaat gacggacgtc
    10021 ctcattccac agcgatgaca aagaatccag ttgcccaaac gttccactgc tgcgatcttc
    10081 tcataatttg gtaaatttac ctcctcacag tctattgctt taatatctct cgtcagaagc
    10141 cttctacccc aaaaatgatt catattattc gccctaaaaa aatatacgaa aaaacaagcg
    10201 atctattttt tggatcgctt gttcgatagt tatactgttc tatttattca cctatgagcg
    10261 cgattgcttg atctaacact ttttcgccat tcatcatacc ataatcagcc atattgatga
    10321 catctaaagg aatgcctttt ggttccagac gtttctcaaa atcagctttc ataaagcgaa
    10381 cttgtgggcc taataacaac acatccacgt ctttatttgc aagattgtta tctgcgtcag
    10441 aagcggacac agcgaaaata tcagagtcga ttccttttgc ttcagcagct ttttgcattt
    10501 ttgttactag taaacttgtg ctcataccag ccgaacatac aagcatgatt gtttttttag
    10561 ccatattttt ctctcctttt taaaacaaac tacgcaaacg ttttcttcgc gtctgttact
    10621 ttattatata aaaagaaaga aatttgtcaa cgttttctaa acgcggttta tttaatcaaa
    10681 tagccaacta gatttcacta atttattgaa cacgacatat tctttgtcca aattgatgac
    10741 aactacttca tagcctgcat ttatccagcc ataggcacct ttttcagggt gtttataatc
    10801 atttgcccac caatctgtac tttcccttgc tgttttggga agtccgttac tgggaaacag
    10861 cagttcgtca aattgggtaa aggtcaacgt tacttgagag ccgccattgt tcttcaaata
    10921 atgcgtaatt gcatcgtact ttttcattcg ttcctgcatc cccagatcca cctgcctttg
    10981 tctttattat cgcatactac agcaattgcg caaccgttac agtgttgaaa caacctagaa
    11041 ctttatttat actgaataaa gaaaatgaaa aaaagaggtg acaagatgat cgagcgctat
    11101 cgtacaataa aagaaaatgg acaaagtgag attgagatca aaaaatcacg ctttatctgt
    11161 tctcttagac gaatagaatc agaggaccaa gcaaaaaatt tcattcaaga aataaaaaaa
    11221 gaacattgga aagcgaacca taactgcagc gccttcatca ttggagaaaa aaatgaaatc
    11281 cagcgaagca gcgatgatgg agaaccaagt ggaacggcgg gcgtaccgat gttggaagtc
    11341 ctcaaaaaaa atcaactgat caatgtagct gcagtagtca ctcgatattt tggaggaacg
    11401 aaactcggca caggcggatt aatacgagca tacactcatg cggtctctca agcattgtct
    11461 gacattggaa tcgtagaagg taccttgcaa caggagatct ctgtgatgat cacgtatccg
    11521 caactaggaa aattacagaa ttatcttgaa ctccaacatt tttttataaa agaaatccaa
    11581 tatactgatc aagttagcgt catctgtgct gtagatgaaa aaagtgctaa ccactttaaa
    11641 gaatccatca ttgagctgct gaacggacaa gtccaatttg aagagggttc tgtttcttat
    11701 cacgagcaac tgataactga tcatatataa aaacaggtga ttctgattct cttttatttc
    11761 taataaggaa tcagggatca cctgtttttt atttttccaa ataaaactca aaacgatttc
    11821 ctacgtattg cgtacgcaca tactcaaacg gcgtaccgtc ttcaaaataa gaaatctggc
    11881 gcaaacgaag aactgcatct cttcgtttta cctctaaata gtcagcaatt ttctcagaag
    11941 ccaacacagc agtaatcgtt tgattcgctg gaccgatctt tttcccgcct ttttcttcta
    12001 gcgtgcgata caacgattca gtaatctctg ctttgctgta gccatcgatc agcttttgtg
    12061 gaacactggc aacttcaaaa caaataggga catcatctgc gaaacgaata cgttccattc
    12121 gcaagatcgt gtcatcttta ctcaagttta gtttttccat ttcacttgag cttggcgaag
    12181 tcaagaaata agagattgtc cgactagacg gtactcgatt ttgtgattcc ataatttctg
    12241 taaaacttgt tgcaccagac attttttctt gtactttttc tcgcgcaaca tacgtacccg
    12301 aaccgatctt tctttctaag attccttcat ctgccaagtt ttgaattgct tgtctcaacg
    12361 tcatacggct gacattgaat ttcactgcta attctctttc tgaaggaaga cggtctccga
    12421 ctttccatat accttgttcg atttcatttt ttaattggtc atgaatctgt atatatacag
    12481 gtaattgatt cgacataacg tacacccgtc ctttcgtttc ttctattata actggtatat
    12541 acctgattca caactgaaaa agataaaggt ttctatccat caacagagga tttagacaca
    12601 catcgttctc cctactccta ttgtcagaaa caatttttta gatatgttca acctagaaaa
    12661 taacaaaaga ccctaaaatc gatgaaaatg ccgacttatg gatcttttgt tattattagc
    12721 ggtttttagc catccatttt tttgtatgat tcgttgggcg ttttgatttt acctggaccg
    12781 cttttccgcc ttttttcgga atattcactt caatattgta tttttctgat ttgaccaaat
    12841 catataactt ttcagctgct tcgtctactt tttctttcca tttcatgtgg atccctccaa
    12901 ttcttgtagt taacttaact ctatcttaat tcagcagaat cttcaaggaa caaggtagca
    12961 aagcaaaaaa aaagagctct cgaactaa
//
LOCUS       DAFLWQ010000081        12791 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.084, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000081 DAFLWQ010000000
VERSION     DAFLWQ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.084"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            104..1147
                     /locus_tag="L1V16_002289"
     CDS             104..1147
                     /locus_tag="L1V16_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBN1276612.1"
                     /translation="MKKFLVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGTPVYRLYNRYNGEHFYTVDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNVISKQGWKIEGTGWYAMPNS
                     VPNPTPAPSTEKVLNVPVVWQGNTMLCEGASLLEGLHYKGVATNQSLTSFVNYMPKAN
                     DNNPYHGYSGEWRHNVNGTYQGMMADPVVKWAKNVGGNAVNITGSGTNGIKNEIRNGN
                     PVVTWITYNYATPEFKQMPWGRAVWNGHVVLVDGFRNGAYHVVDPVFGAKWINASTYE
                     RAFNVTGMAVAVR"
     gene            1320..1544
                     /locus_tag="L1V16_002290"
     CDS             1320..1544
                     /locus_tag="L1V16_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276613.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEYKENIPKNLQGSER
                     YEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            1547..1804
                     /locus_tag="L1V16_002291"
     CDS             1547..1804
                     /locus_tag="L1V16_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276614.1"
                     /translation="MINEDFRSENKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEDIMKREGFQADNDSKKVE"
     gene            2021..2896
                     /locus_tag="L1V16_002292"
     CDS             2021..2896
                     /locus_tag="L1V16_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276615.1"
                     /translation="MTTNKRWSELVQNTVKKVMPDGYHFNYIQCSQTTESIYFSILNE
                     NRLYYFRVSSHHRKKREDNVTTFLSGKYNGFKELSEAIGEYLKSNRFVRISDKHILIL
                     LLYLNNSFKLFWRDDTFYYIENGMDIYSGINGILKHYIKALLRYGVLYQEDLSNQIKI
                     SNSGKSLLAKYKKLLSPIYKGIDMEAVNSETLFNLVVDEKFANEFFKSKKIERLNNLF
                     PENAIKAYVDNNKSRLYNWFIPKRLRGKIKIGDQVKVINLNHTKIVTVTELYIAEKED
                     ITKMKPVIKILDNKE"
     gene            2906..3700
                     /locus_tag="L1V16_002293"
     CDS             2906..3700
                     /locus_tag="L1V16_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276616.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSRRLRITVEYGTNESATELKQRYLDTRREASKKYDDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMNKYRV"
     gene            3729..4847
                     /locus_tag="L1V16_002294"
     CDS             3729..4847
                     /locus_tag="L1V16_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276617.1"
                     /translation="MGNNSIYTPEMQNKIKRLVGLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKQTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLKTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETSTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFGKSKDEVKGVVIDDDFEFDFD"
     gene            4880..5200
                     /locus_tag="L1V16_002295"
     CDS             4880..5200
                     /locus_tag="L1V16_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276618.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            5455..6144
                     /locus_tag="L1V16_002296"
     CDS             5455..6144
                     /locus_tag="L1V16_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein"
                     /protein_id="HBN1276619.1"
                     /translation="MRTHYIYLEDKIVDEIPAKSREQARKLFIEKYKEINGDSEVPKV
                     VVTVRKRQTKKRSTFHVSPDIYNLIERHRSEDNISISQYIATVIDELISGKYDYAFDF
                     EGEKDYKSVAVFQSDFEKLKNYAGRRNVNFARLLEEFYSEELGVGNEYKRETYAKLSH
                     KLSQALKEVTEVKAELDAKLEEVKKYQTERKNNMKNQVEFDEQKEFEKARKRYNKIMN
                     ELSYEHLTVHE"
     gene            6181..6348
                     /locus_tag="L1V16_002297"
     CDS             6181..6348
                     /locus_tag="L1V16_002297"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276620.1"
                     /translation="MVNEVETLLASFFENGHVNDEWRKEEPKRVNAYIARLKRFIDKY
                     KENSDKFSKDK"
     gene            6368..7996
                     /locus_tag="L1V16_002298"
     CDS             6368..7996
                     /locus_tag="L1V16_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276621.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNDGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQEIKELKGIRKELEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEMIAYLKHK
                     NILLVGGHVNFQNKLTELLPNIKMFDVSENNGKILKNLNTCDAIFLYTDYLNHGLYYR
                     VMSEISNKDKIFYLDNHVNMNLTIKRIYDLLSLI"
     gene            8047..8418
                     /locus_tag="L1V16_002299"
     CDS             8047..8418
                     /locus_tag="L1V16_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276622.1"
                     /translation="MRELTLSSKELEKKTALLNEIFSADCIIQSLKESSFSKLTDQEK
                     ISYMLSLDNLGTKYDESASSDKLLIELVSSLSSFGKMKRFNVILEIFAWLIPSFIWFF
                     YIFIVESELIAKVSLGLLIPI"
     gene            8503..8703
                     /locus_tag="L1V16_002300"
     CDS             8503..8703
                     /locus_tag="L1V16_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276623.1"
                     /translation="MLKRIAWDKDNKTDIELKEYKYNYFSRCIDRKLLFKKEGLEFSF
                     DEDEFEKLVMDWRKNLLDTVQF"
     gene            8837..10063
                     /locus_tag="L1V16_002301"
     CDS             8837..10063
                     /locus_tag="L1V16_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276624.1"
                     /translation="MIFYMFININEVLKLTTITMTKKIEVYVDGSQEERDSFFDFFWK
                     NSREYVKALNLVYKQLMFEELIKDAIKEMDQGYAEREESIQNRIEKLAYTDPIDQKKL
                     DKAKAELSKLRNEKNKEAREILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASK
                     DFGNDFIGIVTGQRTPRIYKNRNKYGLLPFRGRDIKIHKDDKFYIYLPKGFRFKVNLG
                     SKPRKARDVASVLQHIMDGDYKLNQSNLIFDGRKLFFNLTISFEKSYNEMEFKKGNEL
                     IVNFADLCSGECLINDKSVMSFGDSQYIRNFKSKILAMKSKEQSRGVFSKGGHGRKRK
                     LDQDRWEAIKKRESNFVKTYNNQCSAKIVKTAIRNKAQIIRIIEPDKAYGEWAYYQLK
                     EQLVNKGKRYGIEVRS"
     gene            10913..12238
                     /locus_tag="L1V16_002302"
     CDS             10913..12238
                     /locus_tag="L1V16_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBN1276625.1"
                     /translation="MFDYSREPVNDYFLIDMKSFYASVECIERNLDPMTTPLIVMSRS
                     DNTGSGLTLASSPTAKKKYHITNVSRATDLPYPLPKELHIVPPRMNLYIKKNMEVNQI
                     FRKYVADEDLLIYSIDESILKVTKSLNLFTSSGTRSERRRELAKIIKDEIQKETGLIA
                     TVGIGDNPLLAKLALDNEAKSSKEFIAEWTYETVPEKIWKINEMTDFWGIGSRMKKRL
                     NHMGIMSIEDLANWNPYTIKSQLGVIGLQLYFHTNGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPKDYTRREEVELVVKEMAEQVAIRIRQHNCKTGCVRLAIGTSILEEKSGFSHQMKI
                     PITDNTKELQNYCLFLFNKFYEGQEVRHIGVTYSRLVYTDSLQLDLFSDPRKKIAEEN
                     LDRIIDKIRQKYGFTAIIHASSMLEGARSITRSTLIGGHAGGLGGLHND"
     gene            12231..12578
                     /locus_tag="L1V16_002303"
     CDS             12231..12578
                     /locus_tag="L1V16_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276626.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFSELLKWSQI"
BASE COUNT         4968 a         1588 c         2549 g         3686 t
ORIGIN      
        1 caacaacgat tatgatctta aaacaatcgt ttatgtaatt ggcaatctta cgaataattt
       61 tcatgcaata atgacaataa aaaatgaaaa ggggtaaaat caaatgaaaa aatttttagt
      121 aggaattcta ttcacaatgg ggctagtatt attatcacct tcagtttcag cagaaagctc
      181 tatttccatg tatcgtatgt ataatcccaa tagcggagag catctataca ctagaagcgt
      241 tggagaaaga gacaatctga aacgttatgg atggcattac gaaggtgtcg catggcaagc
      301 tccaacaagt ggtactcctg tttatcgttt gtataatcgg tataacggtg aacattttta
      361 cacagttgat gccggagaaa gagataagat ttcacacaca ggatggacgt acgaaggtgt
      421 tgcgttctat tcctacaacg gagcaaatag agttcctgta acacgtttat ataacaaata
      481 cgtgaattgg catcactaca cgttagatca aaatgaaaag aacgtaatta gtaaacaagg
      541 ttggaagatt gaaggtacag gctggtatgc aatgccaaac agcgtaccaa atcctacacc
      601 tgctccaagc actgaaaaag tgttgaacgt tcctgttgta tggcaaggaa atacaatgtt
      661 atgcgaagga gcttctttat tagaaggttt acactacaaa ggtgtagcca caaatcaaag
      721 cttaaccagt tttgtaaact atatgccaaa agctaatgac aataatcctt atcatggtta
      781 ctcaggagag tggcgtcata acgttaatgg aacgtatcaa ggcatgatgg ctgacccagt
      841 agttaaatgg gcaaaaaacg ttggcggtaa tgccgtcaat atcactggtt caggaacgaa
      901 tggaatcaag aatgaaattc gcaatggtaa tccggttgta acttggatta cttataacta
      961 tgctacgcca gagttcaaac aaatgccttg gggtcgtgca gtatggaatg gacatgtagt
     1021 tctcgtggat ggcttcagaa atggtgcata ccatgttgtt gaccctgtat ttggcgcaaa
     1081 atggatcaat gcaagcacgt atgagagagc atttaatgtg actggaatgg cggttgctgt
     1141 acgttaattg atagaattat caactaaatg aaataagagc ttaattactg aaatggtaaa
     1201 taggctctta tttttttaga ggaaattttt gtaatacgaa tctataacaa aaaatattga
     1261 atgtagtaca caaaagtggt atattaaaat cgtagagatt atgcgaagag gtgattttga
     1321 tgaaccaaag aagaagaaaa aggttagaag aaataagcga gcgactttcc gagctaaagg
     1381 atgagttaga agtaattcaa gaagaagagt acaaagaaaa tatacctaaa aatctacagg
     1441 gatcagaaag atatgaaaaa gcagaagaat ccgttgatca acttgaagaa gctgttgatg
     1501 gtttatccga catattagaa ttgattgaag atatagctag ctagagatga ttaatgaaga
     1561 tttcaggagt gagaataaaa tgattgatat ttcactgata gagaagctac ttttttcaaa
     1621 taagtacaca gccaaagagt tggctacaag atggcaaata tccgaatcag ctattaaagc
     1681 ctatcgtcaa aataagggaa gcgtaggatg gcgtgattgg aaaggaatca gcattggaaa
     1741 agcagaagac ataatgaaac gtgaaggatt tcaagctgac aatgattcta aaaaagttga
     1801 atagtttaat agtcgccaag aaaagtacca ggacgagggg aaaggtagat tacaaaggaa
     1861 aacactttta aataaacttc gcaaaagcat caggttatga gtggctaggg ctatacgaat
     1921 gtgatgaaaa caaagggctt taatgtcaaa gaaaacgcaa taggggggga acaaaatttt
     1981 taaaaaagat atttatgttt ggtttaatgg aaaaaaatat atgactacta acaaaaggtg
     2041 gtcagagcta gtacaaaata cagttaaaaa agtcatgcca gatggatatc atttcaacta
     2101 tatacaatgc tcacaaacaa ctgaaagtat ttatttttca atattaaatg agaatagact
     2161 ctattatttc agggtaagtt cacaccatag gaaaaagaga gaagataatg ttacgacatt
     2221 tttatcggga aaatacaatg gcttcaaaga gttaagtgaa gccattggtg agtatctaaa
     2281 aagtaataga tttgtcagaa tttctgacaa acatatattg atcttgttac tttatttgaa
     2341 taatagcttc aaattgtttt ggagagacga cactttctac tatattgaga acggcatgga
     2401 tatttattct ggtatcaacg gcatattaaa acattatatt aaggcgttac ttcgatatgg
     2461 ggttctttat caagaagatt taagtaacca aattaagatt agtaattctg gaaagtcatt
     2521 actggcaaaa tataaaaaat tgctttctcc tatctacaaa ggaatagata tggaagctgt
     2581 aaattctgaa actttattta atttagttgt tgatgaaaag tttgcgaatg aattttttaa
     2641 aagtaaaaaa attgaaagac taaataacct gtttcctgaa aatgcaataa aagcttatgt
     2701 agataataat aaatcacgat tatacaactg gtttattccc aaacggttgc gaggaaaaat
     2761 caaaattggc gatcaagtga aagtaattaa tctaaatcat actaagatcg ttaccgtaac
     2821 ggagttgtat atagctgaaa aagaagatat tacaaaaatg aaaccagtta ttaaaatact
     2881 agataacaaa gagtgagtgg aatatatggt agcaaaaaag aatactctaa aagaagcttc
     2941 tgaaaaatat caagatatga aaagacgagg attaatacca aaggacaaaa aaggtatatg
     3001 gagagaattt gttaaggaag tcagtagtga tcgaagtggc ggtgactttg ttggacgata
     3061 tacagcaaaa ggttatagca ggcgcttaag gatcactgtt gaatatggaa cgaatgaatc
     3121 agctacagag ctgaagcaaa ggtacttaga tacacgaaga gaagcttcaa aaaaatatga
     3181 tgatttcaag agcagaggtc taattcctaa gaagaaaaag gggatttggc gtgagttttt
     3241 caaagaagaa gatagcaatc ggaataaggg agacttcatt ggacgataca cagcaaaagg
     3301 ctacactaag aatttaggga tcaaggttga atacggaact ggtgaaagtt catgggaatt
     3361 gagaaatcgc tatttaaata cattgttaga gaaatataaa gcagaattat tggagttgtt
     3421 cgatgttaat gattttatcg agatggctga aaagtatggt catgaagaag gttttatgat
     3481 caatgacatt atggttattg ataattttac ggatttatta gcacttgcga aaaaagcaag
     3541 ggatttaaga gaaacgcaga tgtatctatt cagaaataaa aacggaagaa accggagaac
     3601 tgaatcgagt gagattgaag attactatga tgcctttaca cacgatctgg gagcctttgt
     3661 agacgagata agtggtgtaa tgaacaaata tagggtctag aataaaaaag ccggagatga
     3721 gcagataaat gggaaacaat agcatataca cacctgaaat gcagaataaa attaaaagac
     3781 ttgtcggatt agggtggatg acaagaggaa aattagattc ttttagtacg atcaaatatc
     3841 ttttgatgga catttaccgt cagaacaagc aaacaggaat acattttttg ggctatgata
     3901 agccggaaga tgcacctttc tttgttccaa gttcagccta tagagccagt acctccggta
     3961 gcatgtataa cttggatttg tttgaggaag gagcaaagat gatcgaatat gatttcaacg
     4021 aagcctattc gaggatcatg agaaattatc ctttgccgtc aaacacttat ttgaaagcaa
     4081 aatataatac agatcaagct attttgagag cgataaatag accaaaagta agaccgtatg
     4141 aaaatttaaa aacgtatatg ttctttttgg ttaattttga aggaacagcc aaagaaggaa
     4201 catatgctaa tccaaaatca cagtcgatgt ttgcggatta tggcgaaaat cccaaaacag
     4261 ctaatgagcc tatttggtta tcggagattg agctaacact tatccttgat tattatgata
     4321 ttaaagagat ggaagtccta gatagccaca catttttgac gaaaaaagga ttactcaaag
     4381 aatattttga aagaatcgag ccattaaaaa ctgatcctga tacgttgaag ctttataaaa
     4441 atcttagaac gaaagtattt ggtgctatcg gacaaaaatc attaagagaa ggagaaacaa
     4501 gcaccttcga taaatacagt atgtataatc gagcgtattc ctccatggta gcaggcgtat
     4561 ttagagatcg tatggttaga tatgaacaga aatacgttca tagcgcatat gggctattaa
     4621 aaattcgtac tgatggattg tatttcagat ccgaagtacc agagtttgaa gagctgtata
     4681 aacttggagt agttaagaaa aaagttcata caatatccaa agaagaagtc gaaaaagctt
     4741 tagaatttaa aaacaaagga tttgaaaata agggctcctt tgggaaatct aaagatgaag
     4801 ttaagggtgt tgtgatagac gatgatttcg agtttgattt tgactaaata ctctttggaa
     4861 aagatggtag gaggtaaata tgaagaagaa aattgtggaa ggaaatgtag gtgttattat
     4921 tctaaaagat tcaactgact atgctaaatc aatggcacta aaagacgaaa aagttgcacg
     4981 catggataaa gatttagttg aatttctgat ggatgataca gaaagattaa aaggggatca
     5041 gtttttgagt ttaatgaaag acaaaggctt aaacacatat ggtttatttg attataagaa
     5101 attagctata gagtgggtaa aagaaggaga aatatttttt attgaagaat gggaaggtac
     5161 tgagaactta gttcttcatc agtatctttt gaaagcttaa tctaagtaaa acagttctga
     5221 ctagttatgc ttgtcagaat ttcaaaggaa gttttccata accatcatca ttcaaaaata
     5281 aaggatttga aaataagggt tcctttggga aatctaaaga tgaagttaag ggtgttgtga
     5341 tagacgatga tttcaagttt gattttgact agattttttt gcaatgttta agagtaaaca
     5401 aggtaagaac taagatcatg aagattgaga gtaaagaaga tagaggacga atgtatgaga
     5461 acacactata tttatttaga agataaaatt gtagatgaaa ttccggcaaa aagtcgagaa
     5521 caagctagaa aattatttat tgaaaaatac aaagagatca atggagatag tgaagttcca
     5581 aaagtggtcg taacagttag aaaaaggcaa acaaaaaaga gaagtacgtt tcatgtcagc
     5641 cctgatatat ataatcttat agagcgacat agaagtgaag ataatatttc tatctctcaa
     5701 tatattgcta cagttattga tgaattgatt tcaggaaagt atgactatgc ttttgatttt
     5761 gagggtgaaa aggattacaa aagtgttgct gtctttcaat ctgattttga gaagctaaaa
     5821 aactatgctg gcaggagaaa tgttaatttt gcaagactac tagaagagtt ctactccgaa
     5881 gagttgggag taggaaatga atacaagaga gaaacttatg cgaaattgtc tcataagtta
     5941 tcccaagcgc ttaaagaagt gacagaagtt aaagcggaac tagatgctaa acttgaagaa
     6001 gtgaaaaaat atcaaacaga gaggaagaac aacatgaaga atcaagtgga atttgacgaa
     6061 cagaaagaat ttgaaaaagc aagaaaacgc tataacaaaa ttatgaatga acttagctat
     6121 gaacacttaa cagttcatga ataattgagt gagggtacag aaaaatatac gatcgcagat
     6181 atggttaatg aagtggaaac tcttttagct tctttctttg aaaatggtca cgtaaacgat
     6241 gaatggcgaa aagaagaacc taaaagggtt aacgcttata ttgctcgatt aaaaaggttt
     6301 attgataaat ataaggagaa tagtgacaaa ttttctaaag ataaataagg agagagtgtg
     6361 attacatttg ccagaaatcg aaggaatatt ttcgccaaaa ataggtaaaa aacagttaga
     6421 tttcagcagt tttccgagcg taaatagaga ttataatcta ggtgatgagg tacagatact
     6481 aaatattgat ttcaaagaac tagacttcgc tgttgctgtt tccaacaaac ccaaggcatt
     6541 ggaacgagtg aaaaaaatat accaagagaa tgatcaaaat atcaaaaata tgatcaaaaa
     6601 gtatagacga gataattcaa aagttgaaga cgttttattc aacggtacgg caaaacatga
     6661 tttgaatgtt tatatggcat taggagtggc tttgtactgt aattcaatta atcagacaga
     6721 tattttggtt aatatcgtga ggaatagcta tcaaaaaata ttaaaaataa gtagcgaaac
     6781 aaacccttat tatgcaatga aatatcttgg ggataattta ttaaatgata aaaaattgat
     6841 gcacaacact gaagagctgt tatctaattt ggctgcgatt aactttctat tcaaaacagg
     6901 ttctgaagat tattttatag ataacgtact aaaaggtgct tacggaacag cattttatcc
     6961 gctttacaat atgaaacagc ataaagccga acaaaaggat aacaaacttg aaattaaaaa
     7021 gatgaaagaa ctattaggta taggatttgt aaaacccaat tcaaaagtca ctattgcttc
     7081 gttagcaact actaacaatg atgggaaaat agtaaatggg tttgacgatt cagatataga
     7141 tatattgtca aaatcatatt tttctttgta tggagatttt gcagatttga tgggtattga
     7201 tagttactta gtcaataatt ttgagatcaa gggtagcgag ctgaatgata ttgtgtattt
     7261 cgttttaatc tctctatatg caattgatca gaataccgag taccgacaaa ttgactattt
     7321 gctagttttt tatagtttgt tatatcagtt cgttttaact cggttgttta aaaatgctaa
     7381 ggaagaattg atcctgaatt ctgattatga aatagcaaaa caaattgcaa gtattagaaa
     7441 agaaaacaaa tctgaagtaa tcaaattaag aaaagaatta agtattgcga gtaaagaaaa
     7501 cggtcggtta gaatctttag tcaaatcggc aaaaaaagaa gaggaacttt tgaagcaaga
     7561 gattaaagaa ttaaaaggaa tcagaaaaga acttgaacag ctgaggtttg aaaataaagt
     7621 attaaagcaa ttgcaggagc aagaacatag acaatcatta aatggtaaaa ctgaagagcc
     7681 ttcactgtct gaaatgatag cttatctaaa acataaaaac attcttttag tgggaggaca
     7741 tgtaaatttt caaaataaat taactgaact attaccaaat attaaaatgt ttgatgtaag
     7801 cgaaaataat ggaaagatac ttaaaaattt gaatacgtgt gatgcgattt ttctatatac
     7861 agattacttg aatcatggtc tatattatcg tgttatgagt gaaatttcta ataaagataa
     7921 gatattttat ttggataatc atgtgaatat gaacttaaca attaaacgta tttacgatct
     7981 tttatcactt atataaagag agaagtgata aataggacac aaaatttgga aagtaggtaa
     8041 gtcactatga gagaactaac tttatcttct aaggaattag aaaagaaaac tgctttatta
     8101 aacgaaatat ttagtgctga ttgtataatc caaagtttaa aagaaagttc attttcaaaa
     8161 ctaacagatc aggaaaaaat ttcttatatg ctaagtttag ataatctagg aactaaatat
     8221 gatgaatcag caagtagcga taagcttttg attgaattag tatcaagtct tagtagtttt
     8281 ggaaaaatga aaagatttaa tgtgatatta gaaatttttg cttggttaat cccttcattt
     8341 atttggtttt tttatatttt catagttgaa tctgagttaa tagccaaggt ctctcttgga
     8401 ctgttaattc cgatataaat aggttcagca atttacttta ataacttgta tacacgtatt
     8461 caaataaaaa agcagttatt acatgaagga ttaagtggta atatgttaaa aagaattgca
     8521 tgggataaag ataataaaac agatattgag cttaaagaat ataaatacaa ttatttctcg
     8581 agatgtatag atagaaagtt actgtttaaa aaagaaggat tagaatttag ttttgatgaa
     8641 gatgaatttg aaaaattagt gatggactgg cgtaagaatt tactggatac ggtacaattc
     8701 taaaagcaat tgaggtcgaa attccgatac ttgaatcatg atctatatta tcgtgttatg
     8761 agtgaaattt ctaataaaga taagatattt catttggaca gtcatgtgaa tatgagctta
     8821 acaattaaac gtatttatga tcttttatat gtttataaac attaatgagg tgctaaaatt
     8881 gacaacaata actatgacaa aaaaaataga agtatatgtt gatggatcac aagaagaaag
     8941 ggattccttt tttgattttt tttggaaaaa tagtagagaa tatgtaaaag cgttgaatct
     9001 ggtatataaa cagctaatgt ttgaagagtt gataaaagat gcaattaaag aaatggatca
     9061 aggttatgct gagagagaag aaagtattca aaatcggatt gaaaagttag catatactga
     9121 tccaatagat caaaaaaaac ttgataaagc aaaagctgaa ttatctaaat tgagaaatga
     9181 aaaaaataaa gaagcgagag aaatattaac gcaagcgata gggttgaaga gtcaaacgag
     9241 aacacgagat gtagcaaaaa aattagactt tgactttgga gattttgttg attccgcaaa
     9301 tatgaaagct agtaaagatt ttggcaatga ttttatcgga attgtgaccg gacaaagaac
     9361 gcctagaata tataaaaata gaaacaaata tggattacta ccttttagag gtcgagatat
     9421 taaaatccat aaagatgata agttttatat ttatttacct aaaggcttta ggtttaaagt
     9481 gaatttaggt agcaagccaa gaaaagcaag agatgttgct tcagttttac aacacattat
     9541 ggatggcgat tacaaattaa atcaaagtaa tcttattttt gatggaagaa aattattttt
     9601 taatctaaca atttcttttg aaaaaagcta taatgaaatg gaattcaaga aaggtaatga
     9661 attgatcgta aactttgcag atttgtgtag cggtgaatgt ttaattaatg ataaatctgt
     9721 aatgtctttt ggtgatagcc aatatataag aaacttcaaa agtaaaattt tagcaatgaa
     9781 atcaaaagaa caaagccgag gagtcttttc taagggcggt catggtcgaa aaagaaaatt
     9841 agatcaagat cgatgggaag caataaagaa aagagaaagt aattttgtta aaacttataa
     9901 taatcaatgt tctgcaaaaa tcgttaaaac tgctattcgc aataaagctc aaattattcg
     9961 tatcattgaa ccagataagg cttatggcga atgggcttac tatcaattga aagaacaact
    10021 agtaaacaaa ggaaaaagat atgggataga agtcagaagt tagtaaatta aacaatcgtt
    10081 gatttggcaa cgaaatagtg agggaaaatc cactcactga agggtaaact ccgtcaagtt
    10141 gtgtgaccag acggaaggac gaatgttgtt gaggttttag aaccatataa aacagcatgt
    10201 ttctcaaatt tttaggataa gggaaattgc tagcagtttg ttttagaacc atataaaaca
    10261 gcatgtttct caaatgagta ctttaaatta attgatggcg ttcctgcttt agaaccatat
    10321 aaaacaacat ggatttaaaa caagaagtaa gtcagttctc cttttacttt agtaaggaaa
    10381 aataaagtat tctcaataaa acttaaaata agcaaacctt tgttttaata gctaatcgaa
    10441 gtaaaaccca aagccatatg aacccctgaa tcagcgaaag tttatgatga tttggattac
    10501 taatagttta ggaattagat ggtaaatcta aattaaacaa tcgttgattt ggcaacgaaa
    10561 tagtgaggga aaatccactc actgaagggt aaactccgtc aagttatgtg accagacgga
    10621 aggacgaatg ttgttgaggt tttagaacca tataaaacag catagttctc aaattgttta
    10681 aaatgattgt caagttaaaa aaatctggga tcatataaaa tagtatagtt ctcaaatatg
    10741 attagaaacc ctattaaaga gcaatattaa gccaacttac ttaaatcgtt taattaagaa
    10801 caataatctc ttttagtcag acttttagtc tgactttttt gtatttccaa aatttattct
    10861 ttacaaaaac gaacatacgt ttgtataatt gcttgtgaat gggggaataa aaatgtttga
    10921 ttacagtaga gaaccggtga atgactattt tttaatcgac atgaagtctt tctatgctag
    10981 cgtggaatgt attgaacgaa atttagaccc aatgactaca ccgttaattg tcatgagtag
    11041 atcggacaac actggttcag gtctgactct agcttcttca cctactgcaa agaaaaaata
    11101 tcatattact aatgttagta gagctactga tttaccttat ccattaccaa aagaacttca
    11161 tattgttcca ccacgaatga acttatatat aaaaaaaaat atggaagtta atcagatttt
    11221 tagaaagtat gtcgcagatg aagatttatt gatttattcg attgatgaat caattttaaa
    11281 agtgacaaaa tccttaaatt tatttactag ttcaggaaca agaagcgaga gaagaagaga
    11341 attagctaaa ataatcaaag atgagattca gaaagaaaca ggtctaatag caacagtcgg
    11401 aataggagat aacccattat tagctaaact tgcactggac aatgaagcga agagtagtaa
    11461 agaatttata gctgagtgga cttatgagac tgtacctgaa aaaatatgga aaataaacga
    11521 gatgactgac ttttggggca ttggatcacg catgaaaaaa agattgaatc atatgggaat
    11581 tatgagtata gaagatttag caaattggaa tccctacaca attaaaagtc agttaggtgt
    11641 aatcggactc cagttatatt tccataccaa tggaattgat cgtacggata ttgctattcc
    11701 accagaacca accaaagaaa agtcttatgg gaattcacaa gttctaccaa aagattatac
    11761 gaggagagaa gaagtagaac tagtagtcaa ggagatggca gagcaagtag ccattcgaat
    11821 tagacaacac aattgcaaaa ctggttgtgt acgcttagca attggtacgt caattttgga
    11881 agaaaaatca ggtttctcgc accagatgaa aataccaatt acagataata cgaaagaatt
    11941 acaaaattat tgtctttttt tattcaataa gttttatgag gggcaggaag tacgacatat
    12001 aggagtaact tatagcagat tagtatacac agattcccta caattagatt tatttagtga
    12061 tccaagaaaa aagattgctg aagaaaattt ggataggatt attgataaga ttagacaaaa
    12121 atatggattt acagctatta tacatgcttc atctatgtta gaaggtgcaa gaagtattac
    12181 gagaagcact ttaataggag gacacgcagg aggattagga ggtttgcata atgattgaat
    12241 ataacgatag aggacgttta aaatggtcgg gattttattt gtctgatcat actgaaagaa
    12301 tcaatgcaga caatgtacaa cgtgctaatc ataatttggc aaaagaacaa atgacgactg
    12361 aagagattgc gaaaatactg agaactgctg tcataaaaaa tagacccgtc tgcattcaaa
    12421 aagaggaacg aaacgctgaa ggttactatc cagatgatgt agtaggaaaa attattggat
    12481 atgacgagct tggtgtattt gtggaagaag aaaaagttca ctatgatgaa attaggaatg
    12541 tttctttctc ggaattatta aaatggagtc agatatgaac attattaaaa aatacgaatt
    12601 cggttatatt acgtatgaac agctaataga ggaattatgg ggatatggtc aacaattaat
    12661 taatgaagtg gggattgatt gcttttgttt ctatattgaa tccggagcag gataccataa
    12721 gaacagatac tatatatttc catatccacc aaaatagtct cttagatatt tttaaatttt
    12781 ctccaaatac t
//
LOCUS       DAFLWQ010000082        12738 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.085, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000082 DAFLWQ010000000
VERSION     DAFLWQ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.085"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            97..540
                     /locus_tag="L1V16_002304"
     CDS             97..540
                     /locus_tag="L1V16_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1276627.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(546..1730)
                     /locus_tag="L1V16_002305"
     CDS             complement(546..1730)
                     /locus_tag="L1V16_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HBN1276628.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            1998..2696
                     /locus_tag="L1V16_002306"
     CDS             1998..2696
                     /locus_tag="L1V16_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBN1276629.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2703..3380
                     /gene="nth"
                     /locus_tag="L1V16_002307"
     CDS             2703..3380
                     /gene="nth"
                     /locus_tag="L1V16_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBN1276630.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3506..4039)
                     /locus_tag="L1V16_002308"
     CDS             complement(3506..4039)
                     /locus_tag="L1V16_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276631.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4336..6717)
                     /locus_tag="L1V16_002309"
     CDS             complement(4336..6717)
                     /locus_tag="L1V16_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBN1276632.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6707..7354)
                     /gene="recU"
                     /locus_tag="L1V16_002310"
     CDS             complement(6707..7354)
                     /gene="recU"
                     /locus_tag="L1V16_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HBN1276633.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7418..7957
                     /locus_tag="L1V16_002311"
     CDS             7418..7957
                     /locus_tag="L1V16_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HBN1276634.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8047..8466
                     /gene="gpsB"
                     /locus_tag="L1V16_002312"
     CDS             8047..8466
                     /gene="gpsB"
                     /locus_tag="L1V16_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HBN1276635.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8488..8855
                     /gene="rnpB"
                     /locus_tag="L1V16_002313"
     ncRNA           8488..8855
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="L1V16_002313"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9064..10230
                     /locus_tag="L1V16_002314"
     CDS             9064..10230
                     /locus_tag="L1V16_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBN1276636.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10276..11772
                     /locus_tag="L1V16_002315"
     CDS             10276..11772
                     /locus_tag="L1V16_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HBN1276637.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11853..12536
                     /locus_tag="L1V16_002316"
     CDS             11853..12536
                     /locus_tag="L1V16_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBN1276638.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         4273 a         2230 c         2630 g         3605 t
ORIGIN      
        1 tcttggtttc agattgggtt ttcctacaaa atatttttat ctttgttgaa taggaaacaa
       61 aaaaacaata taatgaaaga aaaagaaggt gtagaaatgg ataaaagaca actgctaata
      121 gaagaatatc tggatttagc taatgagatt attcatcgta ataaaccaga aatggaaaaa
      181 gaatttgcag gatttactct aaatgaacta gaagtgattg aacatatcgg gaaaatccct
      241 gatcctaacg tgacaaaatt agcgaatgct agttacatga ctagaggagc catcagtaag
      301 ctaacaaaaa aactgatagc tagagggatc ataaacactt atcaaagcga agagaataaa
      361 aaagaaatct attttcaatt gacgccaatc ggacaaaaaa taaggaatag acacgagcaa
      421 ctccatcaaa aatgggtaca gcgagatgct actgtatttg aaaatatgtc aaaagaagaa
      481 tttgacacag tatttcgttt tatcggtcga tacagagaat ttatacgaag tagcaaatga
      541 agctactatt ttttattgta gtgataatag gcaaaaatca taagcaaaaa tccgaatacc
      601 gtcggaagaa atggtgctgc agcataaagc tgtcctgcga ttagcgggcc gatgacgcgc
      661 gatagagatt gtatactttg ggtaccgccc attacaagac cttgctggtt atctgagaca
      721 gaattggata gttggccatt gaatacagga gtaaaaatag aatcaccgaa accataacag
      781 ataatcccaa ataaaaacaa aatcggcagt agaagaattc cagataatgt gatgaataga
      841 taggcgagga tttcactgaa catccctatt cttgtgatct gctgttctga aaattttttg
      901 agcaatcgag gcataatgaa caattgcgag acagtatcca agattccaat caaagagaag
      961 cttaaaccaa ccaacccagc cttccactga aaggcgtcaa tcgaaaattg agaaaagata
     1021 gattgaagag agccagctgc caaccaaaca gcaaaacctg ctgtcaataa aggaataacg
     1081 gatgaaatct tgaataattg ttgtaattgg tgaaaaggtc ttacatggga gaaacttaaa
     1141 tctactgaac gtttttttat tggaaggctt tctagcataa atgtgtagcc ataaacggca
     1201 tttaagaaag taaagagtgc tccaataaat ataggaacag aattccccaa ctcagctaat
     1261 agacccccta taataggacc cagcgttgtt cctataccga ctaaagcacc catccatcca
     1321 aaaactttgg ttctttcatt aggttccgtg atgtcggcaa agtaagcata taaggtggag
     1381 atttctcctg ccgtcaatcc ttcaatgata cgaccaagga acaacatcca tatcgaattt
     1441 cctaaaccaa aaagcaaata tccgatactt gatcctaata aactgataat aaggatcgga
     1501 tgacgcccaa aatgatcact taagctaccg agaatggggg cagataagaa ggcagctaga
     1561 gcataaacag acatgagcaa agtgatatag aaagcttgct gatgtatgga gtgagaataa
     1621 ggcagcgtta aaaacggaag tacaggactg acgatagtaa atcctaatcc agtgaataag
     1681 acagagacgt atccaaaaac tttagaatgt ttatttgtga aactgtacat gtaaaaactc
     1741 ctttatgcaa taatgttaac ttggaaacaa aaatagtgta tagtaatttt gtttccttgt
     1801 caacattcta aggaacagcg aaatctactt aatttattta ttccgaaaag tgaagatacg
     1861 catcaaaaac atgaacaaac aaaaatcaag tagacgacat tgtaaatctg accgatcagt
     1921 gaagtaaata gaaaagaaac ctgttcttgc ttcccatgtt ttttttacgt atactgtgat
     1981 tgagcggagg agaaatcatg ttgaatttag aaaattactt aagcgctgga caaacagtca
     2041 tatctaatct tttacttaaa aattatcata ggatcggtct acaatctgaa gaatttttat
     2101 ttgttctaca gttgcatatg gcacagcttg aaggagatac tttccctgat ttgcagatga
     2161 ttgctatgga tatgggaatc aaacaagatc agatttttca aatactggat cgtctcgtaa
     2221 caaatggatt tatcaagata gaaacgacga ttgtcaacgg taaaaaagca gatcgatata
     2281 atctttaccc catctatgat ctattaggtg agtatttaaa aacacaagaa aaaaaatacg
     2341 aagaaaaaac acaagaaaaa gaaatccagt cagtgtatca attatttgaa caagaatttg
     2401 gacgcccgct ttcttcgatc gagttccagc ggatcggaca atggctagaa gaagaccatt
     2461 atcagccgga aattttgaag ctagcactgc gggaagccgt attaaatcag gcttatagtt
     2521 ttaattacgt tgaccgcatt ttgctatcgt gggaaagaaa aaatctacgt acaaaacaac
     2581 aagtggaaga agaccaaaaa cgaagaaaac agcagcttct tcaaagagaa gtagaacagt
     2641 cagctcaaca agaagaattg ccgaaagtct cactgaaaaa ttggttggag gagtagcgga
     2701 atatgttaag caaacaaaaa acaatggaag ctctagaaac gatgtatgga atgtttcccg
     2761 aagcacatgg agaactcaag cacaataatc catttgagtt attgattgca gtgatcttaa
     2821 gtgcccaggc gacagatgta tcagtgaata aagcaacgcc agatttgttt gcctcttttc
     2881 cgacacccga tgcgttagca gaagcttcaa tcgatgaaat cattcttaaa ataaaaacga
     2941 ttggtttgta tcgaaataaa gcaaaaaaca tcaaagcgtg tgcacagcag ctgattgaac
     3001 gtttcgatgg gcaagtgcca acgtcaagag aagaattgat gtctcttcct ggtgtaggca
     3061 gaaagacagc aaatgtcgta ttgggggatg cattcgggat accagcaatc gcagtagata
     3121 cccacgtgga acgtgtctca aaacgcctga ggatctgcaa actagatgct acggtcatgg
     3181 aagtagaaga aacactgatg cggaaagtac cacaagaatt atgggtaaag acacatcata
     3241 cactgatttt ttttggtaga tatcattgca cggcaagaaa tcccaagtgc gaggtatgtc
     3301 ctttgctatc aatatgtcaa gatgggaaaa atcggatgcg tctaaaagaa aaggcgctaa
     3361 aaaagaaacc acgcctgtag acgtggtttc tttaattgca aataaatgta tgaattatct
     3421 tgttattatg gagaaaagct gtttcgttta tcttttttgc atgaaaaagt aaatgtacat
     3481 actcagtagc taggatggta acttattaca atttattgcg ataaaaataa aagttgttat
     3541 ttttattggg aaaatacccg atgtagaaaa taatgccttc caatatacct ataaaataag
     3601 tccagtattc caaaggatta tataaataag tgacgtatct atctaaaggt gtaataaaaa
     3661 tgataagtga taataaaaaa ataccattta taactaaaca taaactaatg gatttgggcg
     3721 gtttcaggct catcagaaaa atatagattc tggtgaacaa caaccataaa aaagtgagaa
     3781 tcattgcatg agagcttctt tccataaatt ttcctttaag agtagtgctt aaaagtacag
     3841 aaaaaataat aaatgcaagg ataggagcaa ttaaagtaaa tttatttaat aataaacaaa
     3901 atttttcagc ttttttattc ttggaataac gaggtattgt tttcgataaa aaaagatggt
     3961 gcagacaaat tatgataatt aagcatacta tcagataact caaaatgaag ccttctttca
     4021 aaaaattatt caaaaccata tattgtattt tttatttgat aataacaatg ggattattaa
     4081 gaagtggcac taaataaaag actagtgtgt atttagccga tttaattata aacaagtaaa
     4141 tggataaagt atatgtaatg ataaaagaaa aatggatttt ctaattttta agctaaatgt
     4201 tagatcacac atgtatatgc tggatagtct tataaaaaat catgtaatac agcttggtac
     4261 atgattttta tttgtagctg ttttttacat agacacaaaa aagaaaccac gcttgtagac
     4321 gtggtttctt ttttactatc tgtttccaga agctgaggtg ctgctggatg gtgtatggtc
     4381 atttgcagca tccgctccgc tagttgctgg ctcactggaa gaagcaggag gagcagatga
     4441 agacggtgtc gagctttctt cggatgaaga agaaggaacc gttgttgaag acgctggctc
     4501 gcttgtttct gctgtcgtgc tttcttttga ggactcagca gttgattcgc tttgactagt
     4561 agagctagag ctttgagtcg ttgtctctgt tgttgagctt ccaggagtct ggacatagct
     4621 ggaagatgga atagttgttg atggtgtaat tgcattcgat ctagctgtat attgatcttt
     4681 gtagtacagt tcaccgccca cacgaattaa tccgcttggc atctcccagt ctgtatttgt
     4741 cacgttagct gaaacatact gcataagctc gcgataaaca tcagaggcta cgtgtgacga
     4801 ttctgaagtg acaggcgtca tttttttatt gtaacctgtc cacacggaaa tcgaataatt
     4861 tggcgtatag cccgcaaata ggatatctgg atacacccca gaagaaatac caagttttgc
     4921 atactcgtca tctgtgtaat tggatgttcc ggtcttaccg gcttgatata acccagcgat
     4981 ttgcgcattc gtaccagttc cttcagtgat cgtatctttt aaaatgtctg tgatcatata
     5041 agctgtttct ggagacatgg ctgtttttcc atctggctca taagtttctt ctgttccgtc
     5101 ttggaagacg attttattaa catattgagg tttgtaataa gtccctccat tggcgaaagc
     5161 cgcataggct gctgccattt ttaaggaaga agctccgtat tttgtcccat cttgttcttc
     5221 cgtattacta gagatcgcat tcgattgatg gatcgtactg tattcgatcc caagattttt
     5281 taagaaagaa gccactttat ctgaaccgac ttcattgaat aatttgactg ctggaacatt
     5341 acgggataag taaagtgctt ggcgtaaagt aatggtgccc atatattgat tatcccagtt
     5401 tcctacagga gtcgaagtcc cttcatagtt atacggtgcg tcagtaatag tttttccagt
     5461 agaatatttc aaatattcaa aagctggtcc gtaatctgtg acaggtttca tcgtagaacc
     5521 aaaatcacgg gaagtattca ctgctaagtt gttgcctaaa gttacgtctt ctgcgatgtg
     5581 acgtccgcca atctgggctt ttactttccc ggtattggtg tcgataaggg tggaggcaac
     5641 ttgcatctcg tcgtctgggt aagagacata ctgatccgtg ttgacgatat catatagttt
     5701 cttttgggcg tccagatcca aattcgtata aatctctaaa ccgtctgtgt agacattctt
     5761 atctgttttt tcttgtactt cattgatgac ttctttgaca taattatcga cgatcttagt
     5821 attgtcatcg gattgagtta gttcttgcag accatccgtt accggtacat taacagcttg
     5881 atcatattct gtttgagaga ttttttcgtt ttgaagcatc gtatacaaaa cagtatctcg
     5941 tcttttcttc gcctgatctg gataaacata aggatcatag gcggaagggg cttgaggcat
     6001 cccagcaagc aatgctgttt gcggtaaaga aagttctgat aatttcttac caaagtacat
     6061 ctcagaagct gtctccatcc cgtacaagcc gtttgacata tacactttat ttacgtagta
     6121 ggtcaagatc tcttgtttcg attttttttg ttccaatctt acagccatcc acgcttcttg
     6181 ggccttgcgt ttcagagtct gatcctcggc actggtggag aagaaggaaa gtttgatcaa
     6241 ttgctgtgtc aaagtacttc cgccttgcag tccgccagag gtaaagttag agagggcaga
     6301 accgatgatc cgaatagggt caaccccgat gtgtttataa aaacggcgat cttctaccga
     6361 cacgatcgca tcttctaatg ttttcggtaa ttcattcgca gaaatttttt cacgcttttc
     6421 tgcgcctaaa tcttcgaata gttcgccatc ttgtgtatat agtttggaag atacggtagc
     6481 gtctaatttt ttatccgtca attcgggcgc atcttttgcg taataccaga aaagtcctac
     6541 acctgctaaa aagaggatac agaaaaatga gagtattcct aaaaggatct tgataaataa
     6601 tcctttttta tgtgttccag aggactttcc agaacctttg ccagaattct tcttcacact
     6661 ctttttagga gtaggctgtt tctgtcgtct agagcttcta gtttgttcat ttgccattct
     6721 tgctttctcc ttcaatagat aatgttgata aatagaagtc aaccgcgtcc aaataaggaa
     6781 tccgcggaga aataccagtt ttgatctcta ttcctagttc ttcgatcaaa gataaaggta
     6841 gtgatttgcg tcctttttcc ttttgggcgt cccagtaagc aatcaaatga acactattca
     6901 aataaaaaca gcgcttcaaa gacgaaaacc ataacaagac aaagcagacc ccattttgtt
     6961 cgaggcatgc tttcatatgt tcgatttgat gggcatggaa gtttttaaag ggaaaagatg
     7021 ttttgttctt ggtttctttt gcttcaaagt ccaagtaaaa gcctcgatag acgccattat
     7081 agtctgtagt tgaggcttgg gtaaagtagg cttccttgat cacagcagca cttctcttag
     7141 gatagtctac tttcacgatt tggatagggg taggcttttt atggataacc gccaacccgc
     7201 gggaaagata atatttatta ctttcattga ttgcttcttc aaagcgcatc ccccgattgc
     7261 cgaattcagt gatctgattt cttttttctt gaattttttc gacgggagag gcattcttat
     7321 aataaggttg gccatttgga tagcgcaata ccatctttaa tcacactcct aggccacatt
     7381 atagcaaaaa agcggataga aagaaaagga atctgagatg gataagtcaa aagtaatcta
     7441 tgtgtctggg tatcgaagtt tcgaactcgg tgtttttaaa gaaaatgatc ctaaaatcca
     7501 agttgttaaa aatgttttaa aaaaagaact ccatcagtta gcagaagaag ggctggaatg
     7561 ggtacttgtc agtgggaatt tgggcgtcga actatgggct gtgcaaatag tagcggaatt
     7621 gaaagaagaa tatccggaac tatctcttgg tattttgtat cctttttctg attttggtaa
     7681 taactggaat gaagggaacc aagaaaaaaa acaattagca gaacaattag cagattatgt
     7741 cgaagctgtt agccatcaac cctaccaatc acctagtcag ctaaagaatc acactcgttt
     7801 tatacttgag catacagtgg gctgtctgct gatctatgat gaagaattcc ctggaaaaac
     7861 gaagtatttt tttgaagatg cacagaatta ccaagcagat catccctacg aaattcggct
     7921 gatcagtatg gacgatcttc aaaattttag tgaataatcg atattgtgtt tgatttatca
     7981 acttttttcc tatacaatga aaaaggtaga aatgttatta cgtaaatgaa aactagaggt
     8041 gtaaatatgg cgaatttggt ttatagtcct aaagacattt tacaacaaga attcaaaaca
     8101 aaaatgcgcg gctatgatcc cgttgaagtt gatgaattct tagacaatat catcaaagat
     8161 tatgaaactt acagcaaaga actccttgct ttacaagaag aaaacgatcg attgagtgca
     8221 aaagtagctc aattatctaa aactcaagga gcagctcaaa cacgcgtgca acaaacagag
     8281 gcaccaaaga gcgcagcagt gaccaatttt gatatcttaa aacgcttgtc aaatcttgaa
     8341 cgtgaagtat ttggtaaaaa gcttgatcaa caagcaagtg cagtcaaacc agcacaacct
     8401 aatccaaata actacacaaa tgcagacaca agcttagatg ataatgaaaa aacacgtcaa
     8461 ttttaatttt tgattaatga atttgcggtt ttcgggtaat cgcggtctga cttgatcagg
     8521 ctgaggaaag tccatgctcg cacaggctgt gatgcctgta gtgttcgtgc ttagcgaaac
     8581 cataagctaa ggtactcttt ggagtaacgg caggaaaaca agctaaggct tcggctatgc
     8641 ttaagtatcc ttgaaagtgc cacagtgacg aagcggctgg ggaaacccat ccggtggaac
     8701 gcggtaaacc cctcgagcga gcaacccaaa caatggtagg ggcgcttttt gtctggaaga
     8761 agaacaggac aaaaaggcag tataactgca gatagatggt taccgctttg ttttttctcc
     8821 ctggaaaagc aaagtacaga acatggctta tagaaaaccg caaacatcag ggaattaggt
     8881 cgtgacaaaa gtaatgcgtt ataagaaaca agaaaaacat ttgaaagcta tttttcaata
     8941 cttcagatga atcgttctta ttacaaaaca aacttttgta tcaccggtta ttcggaattt
     9001 gagtaaaagt gtggggtagg actgatgtcc cacctccttt ttttataaat aaggagattg
     9061 tgtatggaaa aaaacaggaa gttcaacctc gtcgcaactg cggcaagcgg gctagaagca
     9121 ctggttggta aagaattaag agatcttgga atcgaatgcc aagttgagaa cggacgtgca
     9181 cgttttgaag gaacaatgga aacgatcgct acagctaatt tatggttacg tacagcagat
     9241 cgagtaaaaa tcgtggttgg ggaattcgat gcgtatacgt ttgatgaatt gtttgaaaac
     9301 gtaaaagcat tgccttggga agattttctt ccactagatg cagcttttcc tgtagctgga
     9361 aaatcgatca agtcgaaact atatagcaca cctgattgcc aagcgatcac aaaaaaagca
     9421 atcgttgaac gtctccgtac ctattatcac cgtccagctt ctgtaccact gacggaaact
     9481 ggcgcacatt ttcagttgga agtagctttg ctgaaagacc atgtgatggt aactctggat
     9541 acgacaggac caagtttatt caaacgtggt tatcgcttag aaaaaggtgg agcaccattg
     9601 aaagaaaaca tggcagcagc acttattatg ttgacaaatt ggcgaaaaga ccgtccattt
     9661 tatgatcctg tatgtggttc aggtacgctt tgtattgaag cagccttaat aggccataat
     9721 atcgcaccag gattcaatcg tgagtttgct tgcgaatctt gggattggtt cagtcaagaa
     9781 atcatggaaa atgttcgatc agcagccgaa gaaaaagcag attatgatat tgaattagat
     9841 attactggtt cagatatcaa tggacggatg attgaaattg ccaaagccaa tgcagaagaa
     9901 atcggattag gctcttcgat tacctttaag caacaagcag tcaaagactt caaaacggat
     9961 aaagaatacg gggtcatcgt ggctaatccg ccttacggag aacgtctagg agaagaagaa
    10021 actgttcgga aattatataa agaaatgggc gatgtattcc gtccattaaa aacatggagt
    10081 aaatatatct tgactagcga cttagcgttt gaggaatttt acggacaaaa agcaaccaaa
    10141 aaaagaaaat tgtacaatgg tgcattgcgt acggatctat tccagtattg gggaactcgt
    10201 ccgcctagaa aaaaagagaa agacgaataa tcttactaat tgattcattc aattggatgt
    10261 ttggaggaat agggaatgaa agaaaaagag tttttacaag aagtaaaaga aatcaatctt
    10321 ctacaacaag ctttaggaat cctcgattgg gatacacaaa caggtatgcc tgaaaaagct
    10381 agtgcatacc gaagtgaagt agacagctat ctttacagca tttatttttc aaaaaaaatc
    10441 ggtccaaaaa tcaaagaagc cattcgctat ttttctgaac atccggaaga attgtcggaa
    10501 gttggaactg ccgtttttgc caaagtaaaa gaagagtatg atttggaaca tcgcgtaccg
    10561 gaagatctta tgagaaaata tacagctgcc gtttcttcag cacacggaca atggcaaaaa
    10621 gctagagaaa cacaacaatt ttctgatttt caacacgcat tgaatcaaaa tattgaatta
    10681 acaaaacagt tgatacctta ctggagaaaa gatgaaaaga cgaattatga tgttttgctg
    10741 aatcaatacg aacccgggat gactgtcgaa atccttgata aggtatttga tcagcttaaa
    10801 gaaggaattc tttcgatccg ccgtacgctc caagaaaaag ggactgaacc tgaaacagac
    10861 tttttaaatc ggagaatgac gaaaaaacaa cagaagagat ttgtagtgaa agtaatcgaa
    10921 caacttggtt atgattttag tcgtggtcgt ttagatgaca ctgtccaccc atttatgact
    10981 ggaattaatc cgaatgatgc acgaatcacg acacgatgga acgaaacaga tttcaaaatg
    11041 gctgtttttg gagtgatcca cgaggctggt catggtatgt atgaacaaga catcgatgat
    11101 aaatatgcgt atacaccggt ttatgaaggt acatcaatgg gtatccatga atcacaatcg
    11161 ttgtttaacg agatcattat tggaagtagt cgcagcttct ggaaaaagca atatcctttc
    11221 tttcaagaat gtgcagaagg aacattcgat gatattcctt ttgacaaatt ttatcgttca
    11281 ttgaaccata caaaatcaag tttggttcgt atcgaggcag acagtttgac ttaccctctc
    11341 catatcatca ttcgttatga aatcgaaaaa atgattttca atgaaggggt agatgttgct
    11401 gaactacctg aaatatggaa tcaaaaatat gaagagtatc tgggaatacg accaacaaat
    11461 gatgtggaag gcatcctaca agacgttcat tggtcaggtg caagctttgg ttattttccc
    11521 tcttatgcat tagggtacat gtatgcggca caattacttc attctttgca gcaagaaata
    11581 gatgtggaaa atgttctagc gtcagacgat tattctccaa tcaaaaactg gatgtcagag
    11641 catatccatc aatatggtgc atctagaaaa ccaaatcaat taatcatgga tgcaacacat
    11701 gaaccgctta atccgcaata cctgatcgac tatatgaaag acctgtattt taatgtatat
    11761 caggtaaaat aaaatacaat ttacaaagat agctgaaatt catctaatct atagatgttt
    11821 tcagctattt acttaagaaa gaagtggaac gaatggataa attacaagtg atcgctgatt
    11881 atagtatgga ccaattagcg catgatcaaa caggacatgg gagcgatcat accaaaagag
    11941 ttgtcaagtt agctgaaaaa attttggaga cggaaccgca ggcagaccgc tttgtgacgc
    12001 ttgcagcagc ttacctacat gatacgattg atgataaagt cgttaaaaat gagaacgagg
    12061 caaagcaaca gcttcgtgta ttccttcgct ctttgccaat agtagaggaa cagatctcga
    12121 tgattttttc cattatcgaa aatatgtcct tttctaaaaa tctctctgaa gcggccgaac
    12181 tatctctgga aggtaagatc gttcaagacg ctgatcgtat cgaagcatta ggagcaatcg
    12241 gcattttgcg tactgcttat ttcggcggtg gacatgggca cccgattttt gatcctgaac
    12301 tgtatccgca aacattcaag gacaaagaaa attaccgaaa aggcacgaca gtgatcaatc
    12361 atttttatga aaaactgttc ttgctgtctg ataaaatgaa tactgattac ggatatgaag
    12421 aagccaaacg aagagaaacc ttcatgcgtg aattcttaga agaatttttt ctggaatggt
    12481 ctattgacga tgaaaatttt actccagaca attggatcaa aaataacaaa aaatgatgga
    12541 ggttgtgaca gaagtggtca gctccaagat atttcggatc attttccgta aaagttactt
    12601 ctggaacact gtttaccaag aggtcgtgag cctgccgttc agctccgagt cacaaggaac
    12661 aatttcaaaa aatagcttct cgtgtttgat gaatattgta acttgtgatt cggaattggc
    12721 aggagaacac cgtttatt
//
LOCUS       DAFLWQ010000083        12734 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.086, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000083 DAFLWQ010000000
VERSION     DAFLWQ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.086"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="L1V16_002317"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="L1V16_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBN1276639.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="L1V16_002318"
     CDS             complement(323..892)
                     /locus_tag="L1V16_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBN1276640.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="L1V16_002319"
     CDS             1078..1980
                     /locus_tag="L1V16_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1276641.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="L1V16_002320"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="L1V16_002320"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBN1276642.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="L1V16_002321"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="L1V16_002321"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBN1276643.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="L1V16_002322"
     CDS             complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="L1V16_002322"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBN1276644.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8548..8733
                     /locus_tag="L1V16_002323"
     CDS             8548..8733
                     /locus_tag="L1V16_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HBN1276645.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8795..9991)
                     /locus_tag="L1V16_002324"
     CDS             complement(8795..9991)
                     /locus_tag="L1V16_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBN1276646.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10161..11597)
                     /locus_tag="L1V16_002325"
     CDS             complement(10161..11597)
                     /locus_tag="L1V16_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBN1276647.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11890..12699
                     /locus_tag="L1V16_002326"
     CDS             11890..12699
                     /locus_tag="L1V16_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1276648.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3801 a         2673 c         2250 g         4010 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttgctgtcat ccacccaata agcatctgac agaactactt
     5101 ttcgttgcgt tttttcgtga tacataacta ctggtatata tcctgggtgt ttctgaaaaa
     5161 tcacttgtaa ttgtttcatt atctcgggat cttcccgttc ttctgtaata cgcaaatagc
     5221 aagtttgtga aggatactgg gcttctaact ggttaggatc agcaaagctt tctccaatta
     5281 gttgcagttc ctgattatat ttgctgattt cgctccgccc ttgaacaaag atcactcgat
     5341 caacggcaaa caaattacga tatttacgat aaagagttgg aaaaactgtg acagaaattt
     5401 ctccactact gtcggttcct tcaacaaagg ccatcagttc tccttttttt gtccgaattt
     5461 ctctaacttc cttgatcatc actaataaat tgactggttg attagggacg atatctgtaa
     5521 tcagctgaac ttgtttagct aaacgaagac gatcaaaccc ttctgcagga tgacctgaca
     5581 aataaatacc taagtactcc tcttccagct tcaagcgttc ttctagtgta tagtcagcga
     5641 cttcttcttc ttttaatgcc atgattccca gcaagtcaag acttccacca ctgtaaacga
     5701 tattttggat ttttccttcg agatcaagca tcaattgttt cctgttagga gataattcat
     5761 caaaaactcc tactgctgtc agtgattgca gtaactctaa tttcagccaa cgcttatcga
     5821 tccgtatgag gaattgatcc actgactgga acgggccatt ttgttttctt tcgtttaata
     5881 tatcttctac aaaatcacgc cgaatacctt ttatcgctgt cagtccgaat ctgatttctt
     5941 ccttattgac caactcaaaa ctggaattac tttgattaat ggacggcgag gaaagtttga
     6001 gtttattttt acgtgcttct gcaatatatt ctttcaattt tgatgtgtta tgccgaacag
     6061 aattcatcag gctggtaaag aaagcacctg gatgatgggc ttttagatac gccatttgga
     6121 atcccacgaa tgaataagca aatgcatgtg accgattgaa tccatagttt gcaaattttt
     6181 cgatatattc atatacggtc gctgctgttt tttccgaata tccctgttgt aatgctcctg
     6241 atacaaaatg cgacttttct tcatctaata cgtctttttt ctttttactc actgcccgtc
     6301 gcagaatatc tgactgccct aatgtaaatc cagccatagt cgaggcgatc tgcatgattt
     6361 gttcctgata gacgatcact ccatatgtgt ttttcaaaat cgggatcagt gaatcatctg
     6421 ggtagcgaat ggcttctttt cctttcttcc tggcaatgaa ggtatctata ttttgcatag
     6481 ggcctggtcg atacaatgca ttgactgcgg caatatcttc gatgttttct ggatctaatc
     6541 ttcgtaaaac gttccggata ccagcagatt caaattgaaa tactcctgag gtttcgcctc
     6601 gttgaaacaa gagcagcgtt tttgcatcat ttagcgggat ctcttttaat cggatctcat
     6661 acccttctac tcgcttaaca gctttcaaag taaaatcaat aatcgataag ttgcgtagtc
     6721 ctaaaaagtc cattttcaaa agaccgattg cttctacctc attcatcgta tactgggtca
     6781 gaaaagcttc atcagaaccg cgttggagcg gaactagttc aagtagattc ttatcgctga
     6841 taactacacc tgctgcgtga gtcgaaacat gtcttggcaa tccttctaaa atcactgcag
     6901 ttttgaataa aagttggttt ttttcgcttg cctgaactaa ttctactaat tgatgcgaag
     6961 ttttataagc ttgggtcaat gtgattttca attgattggg tattgctttt gaccagcggt
     7021 ttgcttcact ttgcgataaa ccaaacactc tagctgcatc tctaagaacc atttttgctg
     7081 ccattgtgcc aaatgttgcg atttgtgcca tatgatattg tccatacttt tctcgaacat
     7141 aattcaatac ttcttcacgt cgattgtcag gaatatccaa atcgatatct ggcatcgtaa
     7201 agcgttcggg gtttaaaaag cgttcgaaca gcaaatcata ttctaatgga tccacatctg
     7261 tgatttctaa cacataggct actaatgaac ccgcagcaga accacgacct gcaccggtaa
     7321 cgattttgtt tctatgagca aaagccatta catcccatac gatcaagaaa taatcatcga
     7381 atcccatttg atggatgaca gataactcgt agtccaaacg ttcttggtat tcctttgtat
     7441 agtcagtgat tcggcgttcc acttgcgaat agcataactc tcttaaatat tctccagctt
     7501 gttttccatt aggaactgga taatgcggaa gtaatttctg atggaactgg aattcaaatg
     7561 aaatcgattc agctaaacgc tgggcgccta ttacagcttg ggaaagaccc gctttttcga
     7621 atcgtttgat catttcttgt tctgaaagaa gatagacatt tgctgttagt ggtaaagatg
     7681 cagataaatt ttctaaaggt atttggcttc cctctttgat atgtttcatc acttcaagtg
     7741 caaaaagttc ttcttgttgt aaactagcga tgggatgtaa tgcacaaagc gaataatttt
     7801 cttttatcac atactgatac cattcaggca attgatcagg cgtgttttct gtcaagccga
     7861 tataaaaatt tctagtaaaa acattttcaa gtaaaaactg ccaatgaccg aaaaagttat
     7921 cctctttatt gaaagcctca gaaacagaat gatttgccgg aacaacaaac gctagatggt
     7981 cggtttctgt catttctgca agttccaatt tttcttggat catttttcgg ctggaaagtt
     8041 tcatcagctg ctgataacct atttcatctt ttgcgtacgc aagcaagcca taattttttt
     8101 cttcataagt ataactaaga tgtaatccaa tgattggctg tactccttct tctacacaaa
     8161 tacgatagaa ttcaggtgca ccgtataaga catctttatc cgttatggct aatgaagtgt
     8221 agccttgttt ttttgcttct tgtacatatt ctcgaatacg tatcgtactt tgtaaaagag
     8281 aataagaagt aattgtataa agttgtggga aaaacatctt gcattccgcc ttttttttcg
     8341 ttaaaattca ctagcgttaa aaggtttgat ccttttactt tcattaagat agcaggcgct
     8401 gaagttgatt attccacttc atttgcttgc ttgtaatctg taggaatgag ttctttcgca
     8461 agaactcaaa ttttattgag atttggtctc gtttctttac attcaaagaa aatctggtaa
     8521 aattaagata gaaaagaggt gttctttatg cgatatatcg ttacattatt ctgggctgtc
     8581 gttctaggtc aagtagtcgg ttatattggt gctgcattaa caagcggaac atatgatttt
     8641 actttgacaa caatcatttc attcattgcg ggtgtcatta tccttttgat tggtgcagtt
     8701 gcgccaagaa aagaaacctc tgcccattcg taaaaaaaca gccaagagct tgagatttct
     8761 caagctcttt tttattttct actcctcacc accattataa tctgctgcga agaactttac
     8821 gaaagttgaa taaagaaaga agaatatttg acagaacaaa caaacttgtc acaataaaaa
     8881 cagcactgta attataagca tgcgcgactg tcgatcctag catgggacct aaaacttgtc
     8941 caaagttgct aaacatctga ttgtagctat agattcggct gactccttct tgaggcgtaa
     9001 tcttactgat cagtgtattg acagaaggca tcaaagcgcc agttgaaaag cctaaaataa
     9061 agcgaagtat acctaattgg agcggtgtag tgacgaatgc cataggtaaa taacagcaaa
     9121 atgataaaat gagtcctcca attagaactt tttgattccc aatcttatcc cctagttttc
     9181 ctagtttcgg tgaagaaaag acagcggaaa caccagctat cgaaacaatc aagccgctga
     9241 caaaaaggat attttctgta cttccgctca attcacgaat atataaggtc aaaatagggc
     9301 tgatcgtagt gattcctatc tgtaaaatca aggtcgtaat gaagagaccg atcaaaatag
     9361 agagatgatc catttttgaa aaaatttctt tggtgcttat cagatctttt ttctcgattg
     9421 gatggaaatc ttctttgact aagaaaatgg tcaataccgt tgtgatcatc aacaaagccc
     9481 ctgtgatcaa gaatacattt tccataccaa accactgagc cagtgcaccg cccattgaag
     9541 gtccgatcag atttccagca atcgctccgg tagacaatgt tcctaacgcc catccgctct
     9601 tttctctagg tgcctgtgaa gcaatcatcg ctgtggcatt tggaatatat ccagacaaaa
     9661 tcccattcca aaaccgcatg atcaaaagcc aatacgcgtt tggtacaaaa gccaaagatc
     9721 ccattgttaa tgtcatccct gctgctgcac ggatcatcat gagttttcgg ccttttcgat
     9781 cagctagatt tccccagatt ggtgcaacca cggcagatgc aaaagcagtc acagagattg
     9841 ctagtcccga aaacaattcg atttgatctt ttggtgttcc tagttgctca acataaactg
     9901 gtatgaatgg cataactaaa ctaatacttg caccagtgaa aaaacagcca atccacgcaa
     9961 tcactaaatt ttttctccaa ttaatctcca tctatcatcc ctctttcgtc tcttttatca
    10021 tacctatttt cgaataaaca agcaacgatc tcgccagtaa aaagagaaaa atcccgcaaa
    10081 ggtcatttta tatgtaacgt tctttttatg taaaacaaaa agagatcaga acaaatactg
    10141 ttccaatccc ttctctttag ttaaattgtt gctagaatga tgaagttgat aatgaataaa
    10201 atatcaacga tccacaaagc aacagaaact tgattgtatt ttcctttgat tactttcaca
    10261 attgtataga aaataaatcc tgctgcaatc ccataggaaa tgctatagca caatcccata
    10321 aagatcgatg caaagaaggc cggtaaagct tcttccatat ctagccattt gatgtctgca
    10381 aaagaagcca tcatcattac tccaactaaa atcaatgctg gcgcagttgc ttgatttggt
    10441 acaatggcga tcagtggaga gaataaacta cttaatgcga atagcactgc cactactact
    10501 gaagtcaaac cagtacgtcc accggccccg atcccagctg cagattcgac ataagttgtt
    10561 gtattcgatg taccaaagat agcccccaca gaagtagcga tcgcatcggc aaatagtgct
    10621 ttatccattt ttgttttgaa cccacgacca tcttccaacg cgatctcgtc ttcttttgag
    10681 aaaatacctg tgcggcgtcc tgtaccgata aatgttccga tcgtatcgaa agtatcagat
    10741 aaactgaatg cgatgatcgt catcaatact tgaggaatct tggaagaatc actgaataaa
    10801 gattgcatgc cttcagaacc aaatgctgca ccgaaagttg ttcctaattc tttaaatgaa
    10861 ttacctaacg aattcgtttg ccaatcaatg gaacttaaat caacaacacc cataaaaata
    10921 ccaaggactg tggtcgctac gataccgata agaatagccc cacggacatt ttttacaact
    10981 aaaatggctg tcagtaccaa accaatcaca gccaataaga taggagcgtt gtcaaagttg
    11041 gctaacgcag ggacgattcc accatttatc gtaacatttg tcgcttttcc gccttcaacg
    11101 acagagctcg aaatagctga ctggtctgct gaaaaagata agaatcctgc atttttgatt
    11161 ccgacatacg caacgaaaat accgatcccg ccaccaatcg catgttgaag actttcggga
    11221 atcgcccgaa taatcatttt tcgaatattt gtgacagtaa taaaaatatt gattaatccg
    11281 caaataaaca ccattgccaa ggcttgttgc caagaataac caagcccaaa aacgaccgta
    11341 aaagtgaaaa atgcgttcaa tcccatacca ggtgcctgag catatggtac atttgcgaac
    11401 aatcccatta ccagcgtacc aataatcgat gcaatgattg tcgctagaaa tactgcttgg
    11461 aagggcatac ctgatgctga caaaatcgtc ggatttacga ataagatata actcatggca
    11521 aagaatgtcg ttactcccgc cattatttca gttgatacat ttgtattgtt tttctttaaa
    11581 ccgaaaaact tttccataaa aagttccact ccctgaattt ttttctgatg gaaaactata
    11641 ataataaaaa ataagtaaaa tagggcaaat ccatcgaaca atttcaaatt atatagacgt
    11701 ttcattcgct tttcaacgtt tttttaacaa aaaaagcgaa aataatactt aacgttcgtg
    11761 tttagcttat gtttagctat ttatatagcc ataactgtag tttttgttag gaatagctga
    11821 ttgctcttgt taattaccta aaatatgcta gactaaaaca aatgctagtt gaggaaggaa
    11881 ggacccttat tgaataaaaa attaattgcc atcgatctgg acggaactac cctcaatcaa
    11941 gattcgatga ttacatctaa aacaaaagag actctaaaaa aagcaatcaa tgccggtcat
    12001 catgtcagta ttgctacagg acgcccattc cgaatgagcc atcagtttta ccaacaatta
    12061 gaattaacaa caccgatggt taattttaac ggcgcattag tacacatccc taatcagcac
    12121 tgggatggtg aaagagaaac gttgatcaat cgtgaaatcg cttttgaaat cttatcgcaa
    12181 aaaaagcagc taaatttaga ttttatcgct gctgaaaatc gtgatacttt ttttattgac
    12241 agttttgatt tctttgatga aaaaattttt gcttcttctc gtccaggaga gaagaatttg
    12301 ctttctccta aaaatttgac gacaaatcct acatctttgc ttgtccgaac agacaaacgt
    12361 tttgcaggag ctgtatctgc tgaattaaca cgtcaatttg gcagttatgt cgatgttcgg
    12421 acatggggtg gacctactgc catcttagag attgtttcaa aaggaatcca aaaagcaaaa
    12481 ggcgtgcaag agattgctaa ctacctgtct atcgatcaaa aagacgtcat tgcctttggt
    12541 gacgagcata atgatttgga attgttggat tatgcaggtt ggggagtagc tatggctaac
    12601 ggtactgacc aactcaaagg cattgcaaat gatgtcactc ctttgagcaa tcaggaagac
    12661 ggtttagctg tttatctgga aaaactactt aaactataat agagaattag attccacaaa
    12721 aaagaggttg tgac
//
LOCUS       DAFLWQ010000084        12404 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.087, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000084 DAFLWQ010000000
VERSION     DAFLWQ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12404
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.087"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(122..520)
                     /locus_tag="L1V16_002327"
     CDS             complement(122..520)
                     /locus_tag="L1V16_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBN1276649.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
     gene            complement(710..1477)
                     /locus_tag="L1V16_002328"
     CDS             complement(710..1477)
                     /locus_tag="L1V16_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBN1276650.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFKDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LKIDFAKVRKGRNYNFAVQFNISSEFDEKPYREKKLG"
     gene            complement(1512..2735)
                     /locus_tag="L1V16_002329"
     CDS             complement(1512..2735)
                     /locus_tag="L1V16_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HBN1276651.1"
                     /translation="MESYQFQVFKLVPSLERRGNRMKITEKNVNPKFETTESNLKKFD
                     LTVTLSNQLVDSIVEMDAMPQKIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSS
                     SSKHSRLKQVIEKLHQQSVIKIQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSS
                     IMPLLTNLEDHFTQYTFDQVVNLTSKYAISFFQLFTKDFNLYEANRDNLTWSTKSLDR
                     LKNPVFSIADLRKKFSIEKKYKAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTY
                     TNIKFLLTRTMSVPVPYKQEQRDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFL
                     ISSADLCDLKLMSRLQNKVYPLYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYL
                     EKSITSYLPYVNLYD"
     gene            3716..4519
                     /locus_tag="L1V16_002330"
     CDS             3716..4519
                     /locus_tag="L1V16_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBN1276652.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKDLSDKLGNLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
     gene            5104..5559
                     /locus_tag="L1V16_002331"
     CDS             5104..5559
                     /locus_tag="L1V16_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276653.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            5678..6736
                     /locus_tag="L1V16_002332"
     CDS             5678..6736
                     /locus_tag="L1V16_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HBN1276654.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLDERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVSKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            6778..8727
                     /locus_tag="L1V16_002333"
     CDS             6778..8727
                     /locus_tag="L1V16_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBN1276655.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKSEDKENEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQL
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFK
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPRKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            8730..12371
                     /locus_tag="L1V16_002334"
     CDS             8730..12371
                     /locus_tag="L1V16_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276656.1"
                     /translation="MKFKKYLLQNLRIKRWVVRGLVIGGVLAVTLGAPFGMNDPTPDN
                     QDSKQETVINKNVAYAESKPAEQGMWTLYARILMGDKEVNDSAAKTGQMNLLGQGGIS
                     ADFPYSDISKQGNSIAGGNAGTQLASTLATYSYYGYIETVSGNAIASQASSILGSIGR
                     TIGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGEGGSDVSNPVSKALTSLL
                     NNLGLNNELFKAIASLSMLFFTAILGYQGMKLLSKDGVNSKGLSPVLEKWIVRIFVLF
                     IFLPVAGSLLGVYINGIQSAKKDGDIPTNVVSDYIINTRLWASTQNLAPSSDTGGDVP
                     DGKPTSEIKFVDTDYEPSKKSAMIRAINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NINTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGSAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTAHNFDATQPWGVANNATFSTQSVALLLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFIRIWEVVLTGSLASGAGVMAISLGVVTTSLIGLQLPIFLITFIRAFGDTAV
                     GFIPNTLVGDGVANIVRSAMILGVGYLLVFKKGEKVNNLINMLIGLPLEVAFGFDERA
                     KLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGNSSVKDMVAGGLGAVGAQKMAER
                     LNNMGDSNADAKSIADKVIPETPEGMSFNGGGVGSTINNTSFKDLVRQDQLRNNSQQY
                     IDHLGRMVDENGNFVDENGEILKDSKYGKDAKGNFIDEKGRLVDEDGNLIDTNGKPLE
                     DSEDGNIGMDSEGRLIDEKGRLVDEDGNLVDENGRRLLNGDFGHDSNGRLVDEKGRLV
                     DEDGNLVDEFGNKLGKHSDGYNVNGDLVDEDGNIIETRDALVADRNRELEQQRHTPIA
                     VAIPENEEDEITLDQTHQELRNEMSGEDVSDRVHRELGDGASGESQSRELNSNFDNSA
                     IRNDTVLKDRESLTKETDKEQSDVKKKFIPTPNVNQTDKYETNIGSGMSKDNQSIREP
                     ELTNKNNRTNNSKSTSDNSGKSNQSTKKTSTAKSAVEYLSKTGKNVYTSADKALAKAP
                     KGSLAGITYEAKNEAIKIGKGTAKVAKATATGASKTGKVVKKSTMSVKDYIVKYGNQK
                     STENKSEDE"
BASE COUNT         4325 a         1866 c         2348 g         3865 t
ORIGIN      
        1 aatttaaaag ctctcagaac gcttctgaga gcttttaata tattctttga taatttgtct
       61 ttcttaaatc catacgtcct aaaacaagct gtttttgctt aatatgatca tctgagagac
      121 atcaaatcaa cttttctctc aacaaatcat tcaaagcttt cgacagatta atattctctt
      181 cagccgctaa aacatttaaa tagtgttcca cagtcactga ttttcgatca taattttgct
      241 tgtttcgagc tttagcaact ttcgtattag cttttacgac aaataaatta acattctcag
      301 atcgcttgat tcttgcattt aactcttgaa caggcgtagg cgatggaatt tctttttctt
      361 gcaactctaa aagcaccaag tatccttcca atacttcttg cgccatctca aaagcatctt
      421 ctaaagtttc accatgcgta tataagtctg gaaaatctgg gaatttaact gcatattcat
      481 ttcctttcca ttcgaatact gcacaaaaaa agtatttcat cgcattgcac ctctctaatt
      541 aaaaaataat ttttgctttt tggtttcaaa aaaagaatcg cctaccaaaa aattgatagg
      601 cgatcacaag ctaattaacc tctaaaggag attaatacct tgctcccaag gcactacata
      661 tcttaacata cgtctgaagc atcttcaaac gagtaagata tattttgcat taacctaatt
      721 ttttttctct ataaggtttt tcatcaaact cactagaaat attaaactgg acagcaaaat
      781 tgtaatttct gccttttcta actttagcaa aatcaatctt cagcattgat ttttcattaa
      841 tttcttcaac tgattccctt aaaacacgtc tatcaaaatt cgatattgtt ttatactcat
      901 tttctgtttt cgtaatctca cgaattttaa ctatttcaat caggggattc ttatatattt
      961 cagctttctc aaaatctcct ttatttttgg cgataagata ttttttataa tacatcgcca
     1021 aatatttgta taacacgatg ctatattttt tttgaaaaga tgctaagtct ttaaaaacaa
     1081 agaacggata cttctttttg attgagacaa ttaagggaat tacatcttct gaaaaactga
     1141 aagatacact atgctcttct aaatcccaat gaatccgatc aatagcagat acagtagtat
     1201 acgtcttata tttcttgtct agattcgata tttcataaac tgcttgtctt tgcaaagtgt
     1261 taactatggt ttttagttcc gtttcaagat tttgatcaac atccatgtaa ttaataatcg
     1321 ctttaacagg taaatctact acgcctgttt tctttagctt tgtgggtgag atataactga
     1381 acagcaattg ataaagttca tacgacttta aatccatttt catatcaatt gttgctaaga
     1441 actcctcatt gtactttgtc agttcatctt ttttcaaaag tttttccttc cttcacgcat
     1501 tttttcagtt gttaatcata aaggttcaca taaggcaaat aactcgtaat tgatttttcg
     1561 agatatttaa cagtattttt tattgtgtaa tcctccttat gagtagcaac gtaagatagg
     1621 tgattgacaa ctgattcaaa tcctctatct ttggataaac gatcataaag cggataaact
     1681 ttattctgaa gtcggctcat aagtttaaga tcgcataagt cggcagaact gatcaaaaag
     1741 tttttgatta gtaatttagt gtatttgcta ttcatagctt tcaagtacga ttgattcatt
     1801 ttctctgttt tatcttctgc gccttttaaa taagcagggt ctctttgttc ttgcttataa
     1861 ggtaccggaa ctgacatggt acgtgtaagc aagaacttta tgtttgtata agtatgaccc
     1921 ttcttgataa gctcatagtc aattttaaaa tcagtgtatt tattcagttg ggcaatcggt
     1981 tctttaatta cacgtctttc aaagtctcga aaagctttat attttttctc aatactaaat
     2041 ttctttcgta aatctgcaat ggagaaaaca ggatttttta atctatcaag tgattttgta
     2101 ctccatgtta agttatctct atttgcttca tacagattaa aatctttagt gaataattga
     2161 aaaaaactga tcgcatactt gcttgtcaag ttaactactt gatcaaatgt atattgcgta
     2221 aaatgatctt ctaagttcgt taataaaggc ataattgaac tactaaattt aatagatact
     2281 gcatcagaaa aatcattgaa ttcagtaatt tctagcggtg agatgacttt gtattcagtc
     2341 ttaccgttag gtttagttct ttgaatttta atgacagatt gctgatgcaa tttttcaata
     2401 acttgtttta atcttgaatg ttttgaagaa gatgaactag aagacatcaa cgcaaataaa
     2461 gcctttttag atactttgac ggtattatta aaaggcggat ttttagggtc aagatgtcct
     2521 atagcgtaaa gataaatttt ttgtggcata gcatccattt caacaatgct atctacaagt
     2581 tgattcgata aagtaacagt taaatcaaac ttttttagat tgctttcggt agtttcaaat
     2641 ttcgggttta cattcttttc tgttattttc atacgattgc ctcttctttc taagcttggt
     2701 acgagcttaa aaacttggaa ctggtacgat tccattgaat aagtatagac ctgttttcga
     2761 tacgttacaa taagaaatgt atcgtaaatt tataacataa ctcaatgtca gtaaaacaca
     2821 ttttattttt tccaatcaaa tttcattgaa aatacagcag aaatcgctat tttagaacat
     2881 tttcaaaata aaaatccttt tcaataaaat acgaaattat aaaaattacc aaaattaaaa
     2941 aacaaatatt tttctagttt ttagaaataa attcacatac tttttctttt tttggatata
     3001 ttcggaatac cacatcgctt tttgtccacg tttgcatcgc tttttgtcca cattcacatc
     3061 gctttttgtc catgttcgca tcgctttatg tccaccctaa aatctattta agattgatat
     3121 aaagcctttt tggaggttgc taaagtttta aagattaaaa tatatattat aaatataaat
     3181 aaaaggggaa gctgaagctt cctccttttc ctttttttca attattcaaa gttacacaag
     3241 caaaataaac tcctagatag tgttagtttt ttttaagatt ttttattttt aagattttga
     3301 aataagagag gagtaatcct cctttattaa atatctgtta atatatctgt taaatatctg
     3361 ttaatatatc tgttagggga ggcttaatct cttgggagag taagtattaa aggggtataa
     3421 aggtaacact tttggacagt aaaggtaaca aaagtggaca gtaagggtaa cagttttgga
     3481 cagcaaaggt aacaaaagtg gacatttgag gtatcacact aggataagac gttaccttcg
     3541 gttttcttga tttggaaggc gaaaaaatag aaaattagat tagtaacaaa tctttgttga
     3601 ctgttacctt tagttgtgat ttaatttagg taacaagcag aaaaaattgt ttcctttaat
     3661 tagtaccaga ttaacatgat taaaggagcg caaaaagaag attggagagt aatcaatgtc
     3721 tcaagaagtt accgaaaaga ttattgatag tgatgtagat ttagtatcag aacaaacaaa
     3781 tgcaattgtg cgttataaca atggtctgaa tacaacagct ttgcgaggat ttaagcctgt
     3841 tgaaatggat gtgttttggg ctattttatc aaaaatgaaa cgtcaaggaa cagcagaagt
     3901 aacttttgat ttcaacctct ttcgttattt ggtcaaatac gacagaagag aaaaggacag
     3961 tttttattct gtgttaaaag atttgagtga caaactaggt aatttaacct accgttttga
     4021 agattcagac gtctatgaac agctgtggct ttttcaaaaa ttccggatag ataaacagaa
     4081 ggaaacagtt acaattaagg caaatgagga atttgaattt atcttaaact caattggcaa
     4141 aaactttact cgttttgaac ttgataattt tacaaaacta agaagtagct acacaaaaga
     4201 attgtatcgt catctcatgc aatacagaaa taaagagtgg cgaaatggtt attgggtagt
     4261 caaagttgaa gattttagaa gagcattaag tataccttca agttatagaa tgacaaatat
     4321 tgataaaaga atactagagc aggcgaaaga agaattttta gctcctgatg aaaacggaat
     4381 acaggtattt gaaacttttg attatgaaaa aatctatgca aagaaaggaa gaagagttga
     4441 tcggctcaga ttcactttta gtgagccaga atcaaacttg ccaaccattt caatgcataa
     4501 ttggttagaa gaagattgag aagaagcagg ttgtaatttt aatacaacct gcttctttaa
     4561 aaaagtatgg gtaacacttt tggacaataa atgcaagaag tttttttgta agcaagtttc
     4621 agtctaaata atatttgaaa gaatggctaa tctatacaaa ttttaacaac tatgggtaac
     4681 acttttggac aagtcaagaa aaaaaacaat ttttcttaat ttgttgatcg actaaaggta
     4741 acacttttgg acaacacaga ataaaaagtc cggtgatatc agttttggta ggaaacatct
     4801 taatatcttt gtgagattga aggtaacatt tttggacaag tcaactattt gttaaaagtt
     4861 aatatagagt aattagataa gttttttctt ttcgtctgat aaatggataa tattagttat
     4921 tttattgcta attagtcttt catgatgact gaaatagcta aaataaatat ctcgttggat
     4981 aattgctgat actttaaggg atatctaaat ttgctgattg atttatttat gttattatga
     5041 tattataata acataaatgt gttacgcccg aacctcattt taaaaaaatg aaggggtgag
     5101 acaatgaatg ctattaattg gcatgaattt gttaactata tggagagctt actagatgat
     5161 ctaaaaagtt ttagtattgc tgatgcagta aagcatgggt taccagttag tacaacgatg
     5221 aaattacgag gattgaaaat tccagatgaa attattaagc tgagaactaa aacaattatt
     5281 gaaaccgcaa aagtcgttga caatatgaac catgaactaa aaggcaagaa aacaacttac
     5341 gagaaagatt ttgaacgttt tttaaaatct gttattggaa aatatctagg taaaaaatct
     5401 ttcagtgaat tgagagatga agagattgta cctactccaa tggttagcaa aatccgaaaa
     5461 aacaaagccg aggggaatta ctatcttggt acaatagcaa aaatcattga ttatttggaa
     5521 aataaagagc aaaagaaagg aacgaagaaa ggaagataat ttttgtgtta aatattaatg
     5581 gggaagaata taccgaaatg attcaaaatc ccgaacctag aattaccgaa aaaacgtctg
     5641 attgtttgct cttttatgaa agggggcaga caaactaatg gaaaaaaacg tcaattcaac
     5701 atctaccaaa gatcaataca gtattattgg agggttgctt ggtgataagg ataagagaac
     5761 acgtcacgga ttacgcatta tgcttgcaac ttttctagga gtgctttttt tattaacagg
     5821 cttgggtagc tacatttatc aattaggaaa ctataattat tatctcgtga acaatacaac
     5881 acctataggc tcttcattgg agtttgctcg atcaggagca gagatcacta tttcagatgt
     5941 gtggacagat caaaacagag atgtaacagt agtaaaactc ggttactcgc aaaacgctag
     6001 aaagttgtta tctacgcaag gaaaaaacta caacttatat atggcaacga aagaaaaaga
     6061 tcgtcctaaa aagcttgaaa tgagctatgg gatgttaagt actgatgggg atgctttctt
     6121 attcctaaaa ggtaaattag atgaaagagc ttatcaagtt tttattgcaa accaagtatc
     6181 actaatttct ggtgatgata cagctgacga tgataccaaa gtcaatgtga atgaagcaga
     6241 ttcagttaca aaagcacttt ctcaatattc tatgaatgat gttaataatg aaggagtaat
     6301 ttcttttggg aaaaaagcaa aacctgttaa tactcctgat aatatcaatt tcagaataaa
     6361 tccatattca gattcaacta atgtctatca aggaagcttt cttaccaaag atggcgatat
     6421 tgattattca aaagttgtag cagttacaag taagaataat gttgtaagta agttagaaga
     6481 tcagttaaat gcttcaaata ctaacatcaa gaaaattgaa gctacaaaag ctgagtatct
     6541 ggaacgttta caacaaaatc ctgacgataa agattcgcaa gaaagtattc gtcaactaga
     6601 cagtcgaatg gagaccgaaa ttaaagcaat caatgataca caaaaattga ttgatcaata
     6661 caaaaatgct gactttaaca aagattcttt tggagacatg aagacgacat ttaagtacct
     6721 aactctgact gactagaagt aaattattct tattttagag gaagtgaaca caaacagatg
     6781 gaaaatagta ccgagttttt taagaatatt caaactgaat ttaatcatgc tctcacacca
     6841 atgaaaccac cgaaacataa gttagtggga cgtgatgacg aactccatga gttgtcactg
     6901 atcttgaata gaccggaaac accgcaagct atcttgttag gtgaagccgg aacaggtaaa
     6961 acagcacttg caagtgaatg ggctgaaaga cagcgacaag atggaaagaa agtacaagta
     7021 tacaaattat caatcggaca attgcgtgtt gggggagatg atgtcctcca aacacgttta
     7081 gaaacattaa ttccaagatt gaaagaatat gagcgaattt taaaatctga ggacaaagaa
     7141 aatgaatttg tcctcttcat tgacgagttt cataaagttg ttagctcttt tggtagtggc
     7201 aataaaattg ggggtgattc gctaaaagaa ccgttagcaa atgaatcact tcaattgatt
     7261 accgctacta caagaaaaga atatgaaaac tatatcaaaa gagatgatgc cttagggaga
     7321 cggttacaac cgttagaatt gaatgaacta aaaagcgatg ttgtcgtcga tattttgaga
     7381 caatggctaa atacatcctc tgttaaagat gatcctcagg cttcttttaa attatcgcaa
     7441 aggattcctg atgaattact tcaagaaatc gtacaagcaa acaagcttta tcgtgaggat
     7501 ttgtccgaac cggctaaatc aattgccgta atggaggatt tgattgcaaa agatcgagta
     7561 gacggaaatg cttataatcg agaaagtcta ttgcaaatat ttggtaagta taatattcag
     7621 ctagattctg attttgatat ggaaaaactt caagaggaat taaagtccat aaaagggcaa
     7681 ccgttagcag tttatactat aacaatgttg tttaaacgta tgaagcttgg atttgatcgt
     7741 tttaaaggtc gaaagcaacc aaaagcaact gctctgttta caggatcaac aggggtcggt
     7801 aaaactgcaa tggctaaagc cgtggcaaga ggactttatg gcgatgaaaa taaagttctc
     7861 ttagttaata tgccggacta caaaacaaaa gatgatgcaa tgcgttttag acgactcata
     7921 ggtactcatg taaggcatga tccttctgcg attattgtgt gtgatgaata tgagaaagct
     7981 ggtgtagaaa cactcgatgc ctttttatca attttagatg aaggtaggat aagttttact
     8041 gaaagaggat gggatgatcg agaagttcac gacactgttt cattgtcaaa tacaatttta
     8101 tttgcgacaa caaatgcagg tgcggagatg ttcgattcgt taaacagata tagctcacta
     8161 tctcgtgtta caaacaagga aaattctaat gaatatagca ctgaactaaa aagagaatac
     8221 cgaaaagtcg catcagggat caaacaagcc ttgattggtg aaggtctaaa gcctgaagtt
     8281 attaaccgat ttggacgaat agttccattt tgggctttat ccgaacaaac tcttctggaa
     8341 attgcttata atgaaatgtt gaagagtgct gaattagtac gaaaacattt aaatatagat
     8401 ttacgtcttc cacctaggaa agaaagagta tatggtcaaa atttttatgc agacgatctc
     8461 tccatgcact tagtttttga catggcttca caagaggatt ctaaatcagg gggtgcaagg
     8521 aatatcttgc atttagttga atctgagttt gaagaagcga ttactgaagc aataattact
     8581 tatccaaacg caaaaatatt cgatgttaag ttgagtgaag ccggagcgtt tgaaggaaaa
     8641 ggtgattcta atgctgaaat tattgcaaag ccttccgttg ctgaaagtaa agaaaacaag
     8701 attgtatttt cgattggagg ggcgtagcta tgaaattcaa gaaatattta ctacaaaacc
     8761 ttagaataaa acgatgggtc gtaagaggtc tagttattgg aggagtatta gcagttactt
     8821 taggcgctcc ttttggaatg aatgatccaa ctcctgacaa tcaagatagc aaacaagaaa
     8881 cagttataaa taagaacgtt gcatatgcgg aaagtaaacc ggcagaacaa ggaatgtgga
     8941 cactatatgc tcgtatccta atgggagata aagaagttaa tgatagtgcc gctaaaactg
     9001 gacaaatgaa tttgttagga caaggtggta tcagtgccga tttcccttat tctgacattt
     9061 ctaaacaagg taattcgatt gcagggggta atgcaggtac tcaactagca tctactttag
     9121 caacttatag ttactacgga tatattgaaa cagtctcagg aaatgctatt gccagtcaag
     9181 catcatccat tctaggaagt attggtagga cgattggtag ttttatcgga tcaattagtt
     9241 taatcctttc taatattgct gaatccataa atgaactcct tggaaaattt ttcatgagta
     9301 tgaatatatt ttctcttatg gggtggggag aaggtggatc ggatgtatct aatccggtat
     9361 ctaaagcatt aactagcttg cttaacaatt tgggattaaa taatgaatta tttaaagcga
     9421 tagcaagctt atctatgctc tttttcacag caatactagg ttatcaagga atgaaattat
     9481 tgtcgaaaga tggtgttaac tcgaagggat tatcaccagt acttgaaaaa tggattgttc
     9541 gtatttttgt attgtttata ttcttaccag tggcaggatc gctattggga gtttatatca
     9601 acggcatcca gtcagcaaaa aaagatggag atataccaac aaatgttgtt tctgactaca
     9661 tcattaacac aagactttgg gcttctactc aaaatcttgc tccatcatct gatactggtg
     9721 gtgatgtacc tgacggaaag cctacatccg aaatcaagtt cgttgataca gattatgaac
     9781 catctaaaaa atctgcaatg ataagagcga tcaatactag cagttatgcc agacaaaata
     9841 atgatctaga ttctaattca gtcggtatgg ctctattaaa agaatggtca tcgaatgata
     9901 ctttcaatat taatacttat gccggtgatg ttaatgtcgc cgaaaatgat gcttatatgg
     9961 gaagagcgcc tgctgtttgg acaggctata atttagggga tggaaaagaa ggaagtgcaa
    10021 ttaagaaacc aaccaattta aatggatata tttggtcagc aaatcaaaat gtgacagacg
    10081 acaatcgcaa gcctgatgga aaaggaacag cgcataactt tgatgctact caaccttggg
    10141 gcgttgctaa caatgcaact tttagcacac agtcggtagc tttattgctc caatcggcac
    10201 ttgatacatc gggagctaag ttttatgcgt ataatatcgc tccttcagga attcaaggca
    10261 gtgctaagaa tatgtcaaca gtaaaaacag aatggcgtac agcatcctta gttggtcatg
    10321 gagctatggg taagtttggc tcgtggctag cgatgaacgc tgaatcaatc gttttagcag
    10381 ttctttactt agcatgtgct tgggcgatgt tcaatgtgaa tatcgtgaaa gcatttaaac
    10441 gtgaatttat tcggatttgg gaagtagttc taacaggatc acttgcatca ggagcaggtg
    10501 tgatggcaat ttcattaggt gttgttacaa catctctgat cggactacaa ttacctatct
    10561 ttctgattac ttttattcgt gcatttggtg atactgctgt gggattcatt cctaatacat
    10621 tagttggcga tggcgtagca aatattgttc gatctgctat gattttaggt gtaggatatc
    10681 ttttagtctt taaaaaaggc gaaaaagtaa ataatttgat taatatgctt attggcttac
    10741 cacttgaagt agcgtttggg tttgatgaac gtgctaagtt attatttggt aatagaaatg
    10801 atgctgtgcg agttgtggac ggcgtttcta aagcaatcaa gaaaagccaa ggagctaaaa
    10861 atccctatta tgatggtggc aacagctcag taaaagatat ggttgcagga ggtcttggag
    10921 cagttggagc gcaaaaaatg gctgaacgtt tgaacaatat gggagatagc aatgctgatg
    10981 ctaagtccat tgctgataaa gtaattcctg aaacaccaga aggaatgtca ttcaacggtg
    11041 gcggagttgg ttccacaatc aataatacct ctttcaaaga tttagttcgt caagatcaac
    11101 tacgtaataa ctcccaacaa tatattgatc atttaggacg tatggttgat gaaaacggaa
    11161 actttgtcga tgaaaatggt gaaatattaa aagatagtaa atacggtaaa gatgctaaag
    11221 gcaactttat tgacgaaaaa gggcgtttgg tcgatgaaga tggaaacctt atagatacta
    11281 atggtaaacc attggaagat agtgaagatg gtaatattgg tatggatagc gaaggacgtt
    11341 taattgatga aaaaggtcgc ttagtcgatg aagatggaaa tcttgttgac gaaaatggac
    11401 gcaggttgct aaatggtgat tttggtcatg atagtaacgg acgtttagtt gacgaaaaag
    11461 gtcgtttagt tgatgaagat ggaaatcttg ttgatgagtt tggtaataaa cttggtaaac
    11521 acagcgatgg atataatgtg aatggagatt tagtcgatga ggatgggaat atcattgaga
    11581 cgagagatgc gcttgtggca gatcgaaata gagaactcga acaacaacgg catacgccaa
    11641 ttgctgttgc aattcctgag aatgaagaag acgagattac tttagatcaa actcatcaag
    11701 aactgaggaa tgaaatgagt ggtgaggacg tgtcagacag agtgcatcga gaattaggag
    11761 atggagcatc tggtgaaagt cagtcaagag agcttaacag caactttgat aatagtgcta
    11821 ttcggaatga cacagtactt aaagacagag aatcgctaac aaaagaaacg gataaagaac
    11881 aatcagatgt gaagaaaaag ttcattccta ctcctaatgt taatcaaaca gataaatatg
    11941 aaacaaatat tggatcagga atgtcgaaag acaatcaatc aattagagaa cctgaactga
    12001 caaataaaaa taatagaaca aataattcta aatctacttc agataattca gggaaatcta
    12061 atcaatcaac caagaaaaca tcaacagcta aatcagccgt tgaatatcta tcaaaaactg
    12121 gtaaaaatgt ttacacctca gcagataaag ctttagcaaa agctccaaaa ggtagtctag
    12181 cagggataac ctatgaagct aaaaacgaag ctattaaaat aggtaaagga acggctaagg
    12241 ttgccaaggc tactgctaca ggagcatcca aaactggtaa agtagtgaag aaatctacca
    12301 tgtcagtcaa ggactatatt gtaaaatacg gtaatcaaaa atcaactgaa aataagtctg
    12361 aagacgagta aaaagaagga gcattgattt gctccttctt ttta
//
LOCUS       DAFLWQ010000085        12222 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.088, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000085 DAFLWQ010000000
VERSION     DAFLWQ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12222
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.088"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..206)
                     /locus_tag="L1V16_002335"
     CDS             complement(<1..206)
                     /locus_tag="L1V16_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBN1276657.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTL"
     gene            complement(203..856)
                     /locus_tag="L1V16_002336"
     CDS             complement(203..856)
                     /locus_tag="L1V16_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1276658.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            1144..1664
                     /locus_tag="L1V16_002337"
                     /pseudo
     CDS             1144..1664
                     /locus_tag="L1V16_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1566..2282)
                     /locus_tag="L1V16_002338"
     CDS             complement(1566..2282)
                     /locus_tag="L1V16_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBN1276659.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(2332..2541)
                     /locus_tag="L1V16_002339"
     CDS             complement(2332..2541)
                     /locus_tag="L1V16_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276660.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            2818..4091
                     /locus_tag="L1V16_002340"
                     /pseudo
     CDS             2818..4091
                     /locus_tag="L1V16_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(4198..5229)
                     /locus_tag="L1V16_002341"
     CDS             complement(4198..5229)
                     /locus_tag="L1V16_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1276661.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(5236..6066)
                     /locus_tag="L1V16_002342"
     CDS             complement(5236..6066)
                     /locus_tag="L1V16_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1276662.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(6063..6878)
                     /locus_tag="L1V16_002343"
     CDS             complement(6063..6878)
                     /locus_tag="L1V16_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBN1276663.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(6875..7699)
                     /locus_tag="L1V16_002344"
     CDS             complement(6875..7699)
                     /locus_tag="L1V16_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBN1276664.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(7689..8789)
                     /locus_tag="L1V16_002345"
     CDS             complement(7689..8789)
                     /locus_tag="L1V16_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBN1276665.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            8967..9752
                     /locus_tag="L1V16_002346"
     CDS             8967..9752
                     /locus_tag="L1V16_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HBN1276666.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            9785..10168
                     /locus_tag="L1V16_002347"
     CDS             9785..10168
                     /locus_tag="L1V16_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBN1276667.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            10244..10375
                     /locus_tag="L1V16_002348"
     CDS             10244..10375
                     /locus_tag="L1V16_002348"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBN1276668.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            10344..10580
                     /locus_tag="L1V16_002349"
     CDS             10344..10580
                     /locus_tag="L1V16_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBN1276669.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(10658..11629)
                     /locus_tag="L1V16_002350"
     CDS             complement(10658..11629)
                     /locus_tag="L1V16_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBN1276670.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         3670 a         2762 c         2229 g         3561 t
ORIGIN      
        1 tccaaagttt gttctatata ttttatttct tttccattca tattactaga aatttcattt
       61 gccatattat gaatcttttc ttttctcgtc tccaaatatg ttttaggaaa gataaaaaaa
      121 attaatgaat gaactaatat aattattatt ccaagaacag aaaatatttg tatgaacatt
      181 tttggaaata tctttaattt tttcattttc tctccaattt atatcctaca tttcttatag
      241 tagttataca gtctaattgt aatttttttc taagttcttt tatatataca tctattactc
      301 gatcataagg agtttcttcg ctatctttcc atacataatc aataatttgc attcttgtta
      361 acacttgtcc attattatcc aataaacatt ttaatacttc tagttctttt gcatttacat
      421 ctatttcttc accatttatt ttagctgtat agctattaaa attaaccgat agatccttat
      481 attcaaactt ctctaaatgt ccataattct tcttaattaa agaatctatt ctagctttta
      541 agaccggcaa tgaaaatggc ttttctacat atccgtctac taaattagta aatgcatcaa
      601 ttttatattc ttcatcacta aatgcagtca agattagaat tggtaaattg cttttctttc
      661 taatttcttt caacacttct aaaccattta taaaaggtat ctgaatgtct aagataacca
      721 aatttatatc gctattaaat tttgacaagg cttctcttcc atctttagct tgaataacag
      781 tatatccaaa ttctgaaaga tattcactta ttccctctct tatcatatta tcatcttcaa
      841 cagttaatat tttcatatat acctccactt aagcctatac actagatatt atacagcata
      901 ttatggctct ataatatcta gtgttggtga cgccttctgt tgccaatact ttttcttttt
      961 tttaataaat gcaaacagac accttgaaat cctttagaaa aaaggcttct ataatatttt
     1021 gtgttgttgg aaaatcgaag gcgattttct actaacactt tttcttcgtt tcaactcaaa
     1081 aagagactca cttttggtaa aatttagtcg accaaaacat caccctacca aaggagtcgc
     1141 tctatggata atcatactag aaaattactc ggattaacag ataaacattt attttttgat
     1201 gaagaatggc tgattgaaaa agaatataaa ggcgttcaag cgcagtttat taaagggaga
     1261 ttggatgact caccttccca ttgtgaacac tgtggatcga ttcgtattat ccgcaacggt
     1321 tcctatacga cacgtactca gatgttgaaa gtcaaagaaa agttgactat tttagaatta
     1381 aaacgtaccc gttttctatg ctatgattgt gggcagacct tttctgcgaa aacggactta
     1441 gttgatgaac atcatcaact aacaaaggaa ctgaagcagg cgattctcat agaactgtac
     1501 gaaaatcaat cacgtaatct gaaaatcaga agaagtaccg tcggctcaag cgatattgga
     1561 aactcttact caaagattcc acgacattgg agccgctcaa acggcattat catcgactgt
     1621 ttaaacgacc aattagtcaa acagaaatcg tcgatgaacc gttgtgcaca atggtgtcct
     1681 gaacgtacag cgacaccttc catatccaga gcagtcgcca catcacgggg atggatgcca
     1741 tccaaattaa aagcaaccac gccagtatga tgttcaggat cttgcggtcc gtaaatggtg
     1801 ataccgccga tcgcttgtaa tttaggtaaa acgtaggcaa ccagttcttg ctcataacga
     1861 tgaatattct ccataccaat ctcattcaag taatcgattg ctcctgcaat gttcggagta
     1921 ccagcttcaa atttccatgg cagctctttc catgaactat cgtaaagatt gacaaaatct
     1981 atcatttcac cgccgaattc gactggctcc atttgttcta acaattgacg tttgccatat
     2041 aatacaccga ttcctgtcgg cccgcacatt ttatgcccgc taaaggcgaa aaaatctgca
     2101 tccaacgctt gtacatcaac tgtcatatgc ggtgctgctt gggcaccgac tggactatcc
     2161 tcaactacaa cagcctgttc aaccctcagc cgtttcaagc acaacaaata accttctgga
     2221 tctggtttgc cgacctgaag atcatcgatc gtcacaaagg aatcaatttt ttccttaatc
     2281 atcggatgtg cttcaaaaaa atagtctagc tcccgcagtt cagaattgag actactccga
     2341 ttttccagtg ctgctgatcc gctgctcaaa atgttcagca tccactggtc tcccaaccgc
     2401 ttgacttatc ccttcataaa aggacagttc tgctgccgtc ccaacacctt gttgatagtc
     2461 tgcaaaagga attttatagc cgaactgctc cagtaaatag gcttcagtaa atagtgatga
     2521 atactctcgt aaaacatcca ttcactgtca atcatcgtcc catcaaaatc aaaaataagt
     2581 gctttggtca tcttctttcc cccttaccca aaacaagcaa aagctgtgtc ctgctctctc
     2641 tacagtatca gcataaaaac tgccgtctga aaagtcaaag gtgaaagaaa tgtggcgcta
     2701 taatttctag gactgatagt aaatcattct atcagtcctt ttgagcataa aaaaacaaaa
     2761 catacagaag ctccgttaga attgaatcac cacaacacaa tcaaaggagc gttctgtatg
     2821 cctgatcttc atcttatcaa actattacta ggaatcaaag atggaaacat tcaaatcact
     2881 catgtcgaga agaaaaaaat acattcaatc aacagtatcg ttgtttctgc cacgctcatt
     2941 aaaacgattc agccctgtcc tcagtgtaaa caggtgaatc aacatgggct gatcgttaag
     3001 aacggaaaga aaaaatcgct ggtccttctc aataagtgtg cgaatcaacg gacttatctt
     3061 gctttggcaa agcaacggta cctctgtcgt ggctgtcaca cctattttac ggcgaatacc
     3121 tacattgttg aaaaaaactg ttttatcgcc aaacaagtac attataaaat attggaggaa
     3181 ttgactgaaa aacaagcaat gacgacgatt tctaaacatt gcggcgtttc ttggtcaacc
     3241 gtttcgcgaa cactcgcttc tctgctcccc atgacaaacg tgaaaataaa ttggttgcct
     3301 cgctgttcat tggtagatga atttcgttca ttgaaaaatc aagtcggtcc ctattctttt
     3361 tcttgtatgg atggcgatac tgggaaatta ctggatattc ttccttcacg taagaagaaa
     3421 gatctcattt cttattttat gcaatttgaa cgacgtgcac gtttaaacgt aaaaatactc
     3481 gtaacagata tgaacgcctc ttatgctttg ctgataaaag agtgctttcc tcatgccaaa
     3541 ctcgttgtgg atcgctttca catcgtcaag cacctcattc gcagttttaa ggatatttga
     3601 ctatgagtca tgaaaagctt cgaccgaaac gatccaatac aagccaaaca ctatcgacaa
     3661 gtgaaggctt tatctcgact tctgatcaaa cgacaggaca cgcttgttta tgataaatgg
     3721 acaaaatggc gtaattttgg ttgggcctat ttaaccgaaa gtgaagtcgt agaacgtcta
     3781 ctttctactt ctgatgaact acgaatagct tatgcttact atcaagaaat tcttcaagct
     3841 ttttatgaca aagaagcgga catcttcttt cagcttgtaa aaacaatgcc caagtcggtt
     3901 ccaagagaac tgcatcatat aaaaaaagcg tttataaact atgaatccgg cattcgttta
     3961 gccttagagt tgccttactc aaatggcaaa atagaaaatc tgcataccca catcaaagca
     4021 ttgaaacgaa tagcttacgg gttaggatga gaaccagaat tttcttaatc aatcatctga
     4081 tcacttatta aacataaaaa aacatctaaa gcagaaaatc aattctacct tagatgttct
     4141 tatatcactc tatcagtcct atttgacaaa gagccagaaa tgtttgccga ctatacacta
     4201 gctttgttgt gcaaaatgct gagtatcaat ttccacaggg attgctagaa tatctttcag
     4261 ctgaatgtat aaggcatcgc taattttctc ttcccgatcg ttcaaccgat ccactaaaat
     4321 ttctttgccc tccagcgttt gaaaaacata ccgttgaatg ttgcctaaaa taaatgattc
     4381 cttccataga accggaatct taaccccctg aggaaccggt tcaaattgaa tcagctccgg
     4441 tcttaaataa taaatgcagc gattgccctt agcggaaaac tcgtgggtat actgattcag
     4501 ctcataccat tcgaaacgat tatagttgcc gataaattcc gcaacaaatc ggctctgagg
     4561 attctgatac aattccttcg aggtggaaac ctgagccacc cgcccagctt ccatcacaaa
     4621 aatccgatca ctgattcgca tcgcctcttc ttggtcatga gtcacaaaaa tcatcgtcat
     4681 ccctagcgat tgctggatag cgcgcaaatc ccgctgcagc tgttttctaa ttcgggcatc
     4741 caaagcactt aatggctcat ccagcagcag gactttcggt tcagtgacca atgagcgagc
     4801 cagtgccacc cgttgtcgtt gaccgccaga aagaaactgg acatttttat ctgcctgctc
     4861 cgtcatatcc accaatgata gcatctcaaa aaccttttcc tgaatcacct caggactcag
     4921 cttctttacc ttcaaaccaa aggctacatt ttcaaaaaca gtcatagttg gaaacaatgc
     4981 atactgttga aaaacaaagc cgatattgcg atccttcgta ggcttatcgg caatattctc
     5041 attgtccagc acaatctcac cgctctttgg ttgttccaat cccgtgatac agcgcagcaa
     5101 cgtagacttt ccgcacccgc tgggacctag taaagtaacc agctcaccct tttcaatctg
     5161 aatttcatca atagctaaaa tctgtttttc atcaaaaaac agattgagat catgtatttc
     5221 taaaaacatt ttccgtcaca actcctttaa gggcttcttt ttcgactgct tctcttccct
     5281 cgtctgctta agggacagct gttgcttttg tcgataagtc agcataaagg tagttaaagc
     5341 aattcccacc ataaacagca aatacaaaac catcacagcg ctagccaaat ggccgttttc
     5401 gttcatccgc cgcagcatat agatgcgtac cgtctgaaat cgaccgccaa tcaacaggtt
     5461 cgtcagcatg tactccccaa aaaccgaaga aaaaatcatc agagaaacta gggtcacacc
     5521 gatacggatg tttggaaaca gcacctggat aataatcgta gacatcgggg cgcccaaggt
     5581 ttctgctgca tccactaatt ccttcagatt aattaagcgc atctggttgt taagactaag
     5641 atagacaatc ggcaacgccg taataaacaa tgcacctacc aacactacaa acattgggat
     5701 accagtttca gcatacgttc gaagcaaagc cgttaccaaa atcactcctg gtaaagcata
     5761 cggcagcagg agcagctttt ccagccaacg attcaaacga gggaaataca aatgaatcca
     5821 aataatggtg ggaatcatca acaacagaat cgtcaccaag accacacctg ctaataaaag
     5881 tgagcgaccc accgcagcaa taaattccct gtccgtcagc agctgttgga accattgcaa
     5941 ggtaaaatca ctaggtaaaa gcgattttga ccatttagtg gagctggcat acaaaatcgt
     6001 tccaataatc ggcagcaagt aatacaggac aaagcagaac aaaatcggtt ttattaactt
     6061 tttcacgtct gcaccacctt gcctttcttt tgaataatca acattgccgt taccagcagg
     6121 acacctaaag cgactgccaa cgcactgcct aaattaggct tggcgaacac atctcccgac
     6181 actaaagccg caattcgaat cgttaaaaga tttacattac tgctggtcag ggcatacgct
     6241 gtttcatagg tccccatgcc attagcaaat aagatgacaa aggtgctggc aatcgatggt
     6301 cgcaaaaaag gcaaagccac cttgaaccaa gcatacgctg atgaagcgcc cagcaattgt
     6361 gcggactcca gccattcctt tttcacttcc ttcatgctgg gatacaaaaa caagacccct
     6421 aacggaattt ggaaataggt atacgtgatg gtcaatcccc accaagaata caaattgaag
     6481 tccgctagaa atggcaaaat cattttcagc acacctacat tccccaacaa aataataaaa
     6541 gagaatgcca gcggaatccc agcaaaatta gctgccaaat tggaaacaaa ggtgattttc
     6601 tcctgcaatt tagtcgatag attcattaag cataaacata aaataaacgt cccgattaac
     6661 ccaatcacac tggagctgac agcaatcagt acgctgttaa caaaggcctg tgtgtaatat
     6721 ttgttgctga aaatatcact gtaattggcc aatgtccact ggttagttaa atcactgtgc
     6781 aagctgcaca gaaccataaa aagcagcggc agcagtaaaa atgcacagaa gataaaggag
     6841 gcaggaacca gaaccaagcg ttttttcatc tctttcatcc cctcatcaat tcttgaatgt
     6901 cctgcatttt ctctgacggt gcaattccta ataaccagca aaacaatgga gccgccagca
     6961 gctgtggtac agtttgttcc ttcagctttt ggcgtttatt tgaaatcaaa taaaaaggaa
     7021 cttcacgatg tgcagccaag ctgccgccat gcagtccgtg cgcatccatc ccgtgatccg
     7081 cagtcaccac gacttgataa cctttttgca gccattcagg aaggtaaata gccaataatc
     7141 tgtccgcctg attaaccgct gctgcatatt catgagaatc ggcggtaaat ttgtgaccga
     7201 catcatcaat attcatcgaa tgtacgacca aaaagtctgg ctgatactga ttcactaaat
     7261 aatgggcatc cgcaaataaa tgcgaatcag ggtaagtgtc ctcactataa aagatgccat
     7321 gctgaatcag tcgctcctcc tgatgctgga tgcgatcaac caaacgatta tagggggctt
     7381 gattgtacaa ctcgctgtac cagtggtaag cggcggctcc tgtttttccg ccagcttcct
     7441 taactaattc aaacagcgac cactctttgg atcgctgagc atggtaatta ctatagatgc
     7501 cattttcata ggctggaacg ccggtcatca gtacttcgta taacggacgt gaattgctgg
     7561 gcagctcact ttttaccttc aataagcttg cttgctggtg ctcaactaaa tgattcatga
     7621 acccaagctg ggcgacggct gtgtcgtagc gacagccgtc tagtataact acaatcagtt
     7681 tgtcaagtct actttgcata ggtcagtacc tccgcctgcc aaagctctgg aagctctaca
     7741 gaggtcttgt tccaagcttc attgtcttca actggcaccg ccgcttcata agcatcctcc
     7801 ggcagtaatt tttcagctac ttctttaggc agctctacct tgcgaatagg tcgcgcatag
     7861 ccctttgcca aattgatttg cccttcatca gataaaatat attcccgtgc tagctttgcc
     7921 gcattgggat gaggggcatt tttattgatt aaggttgtat acccgctaat gatggagccg
     7981 tctgttggca cagttacctc aaaacgctcg gagtcaattt ggtcacgata atttagtcca
     8041 ttgaagtccc aaacaactgc cacatcgatt tcaccttttt caagatttgc tacgctggca
     8101 tcaacggtgg acaaacggcc tttttctgcc atttttttgt agtaattcag acctggctga
     8161 atatcctttt cgtcacctcc gttggcaatc gccgcagcca atacagcaaa ttgtgcttgg
     8221 ttggcaatcg tcacatcccc cacgctaact tgatagtcac cctcttgcag ctccttccag
     8281 ctagtcggtg cttgcttcac attctcttta tcggtgataa aggaaatggt tcccgtatag
     8341 cttaacaacc aatccccatc atcatccttt gcccaatccg gaatttcctc ccaatagttg
     8401 gtcttataag gtaaggttaa ctctttgctt tcagccaacg gaccgaagct gataccgaca
     8461 tcaccaatat cggcggttcc attttttcct tctgattcaa acttagccaa ttcttctgca
     8521 ctggacatat ccgtatccac gtgacttaag ccgtattctt tttcaaggtc gttccaagtg
     8581 cctacccaat ttgcccaagt atccggcatt cccaagctgg caatctctcc ttcttccttg
     8641 gctttttcta taatcgtatc taaagagtcg tctgccgcag ccgattgctt cgttgcttca
     8701 cctgagccgc agcctgtcag caggatactt actgttgctg cacaaaataa accgatagtc
     8761 atgttacgaa ttttttcatt cattttcatt cattcttctc ccctttcgat aattccattc
     8821 taacaaagct ttgtaatgag agaatcagtt tcttgaaaag gtttcatgaa caatgtaaag
     8881 gttgtatatg gtttgtaaat ttcgacgaat tcccgttaac cttctaaagc ttttgcggta
     8941 tgatagtaga aaaaaggagg ctccctatgc agtattatga tcagcatctc cacacgtatt
     9001 tttcctttga ttcagaggaa aaatttgaaa actatttagc ctatcagccg gagtttttcg
     9061 tttctacgga tcactttgat ttaaacaatc catctaccgg aaaagatgac attccggatt
     9121 atccagccta tataaacaaa ctggactctt taaaagaaac ctattccacc aaatttctgc
     9181 gaggtatcga gattggcgtt gttccaggac aagaagagcg gatcgtggat tacctcgctc
     9241 agcatcctta tgatttaaag ctggtaagta ttcatcaaaa tggccgcttt gattatatgg
     9301 acgatgtggt tttaaccaaa gatcccattc aaactaccaa ggaatatttt gatcagatgt
     9361 tgcaggtctt gacggatttt ccagaaggag atattttgac tcactttgat tatggattac
     9421 gccgcttcac cttcacagcg gaagaattcg cggagcattt tgaggctcag ctgctaacga
     9481 ttttcaaaaa ggttgttgaa cgagaattgg cgatggagtt aaatgccaag agcttcttga
     9541 aatacggcaa cgaagacctt taccgttatg ccgttccttt gtatcaaagt gtcggcggaa
     9601 agctctttac cttaggctcg gatgctcatg ttgccgaaga ttatcagctg ggctttaaaa
     9661 aaatgagtca gctgttggca gactgtcagg tagaaaagtt gctagtcatt caaggaaaag
     9721 aacgccgcct gacgccgctg ccgattttgt gattcctata taatagaaga aagtggtgaa
     9781 aaaaatgagc aacctgtggg actacaatca agaggcaccc atccattatt taattgcgcg
     9841 acattgggat gcgttgaaaa ttgaggcggt ttgccgatcc ttgttagcag ccgttccaaa
     9901 acaacaactg gaaaattttt tggtggctga cagcttgcag cgggaaaaag ttcaggctta
     9961 ttttgcagcc tttaaagatc agcctttgga atatttgcat gcgcagtttc atctttttta
    10021 tcaagtagcc gccccagatg actacaacga tttacgagga cagctgcaat tgacctttca
    10081 agcggatgaa accgcctata ccgttttatt gggaatggct cgccttggtg atcaggcgaa
    10141 ggtcgagtgg cggattttcg atatttgatg gcaggatcaa ggcgtttcag ttgcaaacct
    10201 tcctctcttt caattagaaa aaccgcagca ggaagaagtt tgtgtgctgg tcaccgatgc
    10261 tggtgaaatt cgtctccgct tatttcctga ccaagctccc ctggctgtag ccaactggcg
    10321 ctccctagct gagcaaggcg tttatgacaa cacacctttc ggctcgtgtc attaaggaat
    10381 ttgttattca aggtggcgct ttggatggtt ctggtgatga agctgtttcc agctatgagg
    10441 gctttttcgc tgatgaagtg catcgcggac tttatcattt taatggcgcc ttggccttag
    10501 gggaccacgg cccccacacc aacggcaacc agttttttat tgtgcaaaac acaaaggcgc
    10561 aggctgacct gctaatgtaa agcaagcata cttggagctt ggaggactac cggagctgga
    10621 tggtcgttat actgtttttg gacaggtata ccaagggtta gaaatcgtag cagcgatcgc
    10681 agctcagccg acaaacagtg aagatgtacc gattgagcca gtgttcattc gacaaattaa
    10741 cttcgaaaaa acatcgtaaa aagacactca ctgacttcag caaaagctct attcttgagc
    10801 tggctgcagc tagtgagtgt ctttcattta tccataagat aaagcttgga ttcaataaat
    10861 aaataaatgt tttggttaaa gctgtgacca gcaaatgagg aaccgtgcga gccagttgat
    10921 ctgccaatgc aaacatttct ttaggtgaag gcgctggcgt gtctgccaac ggatactcca
    10981 gtcccaatgc ttggtaaccg tgcataccat agcagtggta cggtagtaat tctaacggta
    11041 cgaaccgatc aagatctgcc acaaaacaag caatcgtcag cagctcggtc aggttcatat
    11101 tgatacctgg aaccacagga actcgaattc gcacttcgca gttaggatac tcaattaaaa
    11161 agcgacgaat attcttcaaa atttgttggt tatctaagcc ggtccattgt ttgtggagct
    11221 tgctggtaaa catttttaca tccacaaaca atgtatccac atagggagct accttttgga
    11281 tttcattata agcaccacaa aagctggttt ccagtacggt attgattcca atgtatttcg
    11341 atttttgcaa aatttcttta gcaaaatccg cctgaaccag tgcctcgcct ccgctaatgg
    11401 tcactccgcc atccgagtga aagtaaaaaa cagcatcctt ctcaatctca tccattacct
    11461 cttcagcggt catggtctgg ccaaatcctt tttcaatctg cttgctttgt gattcgggaa
    11521 tcgaacacca ggcacagcgt aatgggcagc cctttaaata aacaacggtc cgtaaaccag
    11581 caccatcatg tagagaaccc tgttctattc ttaatactgt tccttccata tagatttttg
    11641 aattacacac tagtttaaac taaaacacac aaggaaaaac ttaccattta atcataaaat
    11701 tagctcatat aaatatacta ggatgtaaaa tagactggtc aaaatctggt caaaaaagag
    11761 gactaataca ggtagtcctc ttttttgtta ttttaatatt ctaaatcatt ttttattggt
    11821 ttattccctt attcgatgta gactcaaatc actatatcac tagatatcaa acggcgtcat
    11881 acggaatcaa aaacatcaaa tttgacctgt taaatggtca ttgaataaca ttcaaaatca
    11941 ataaaacgga gtcagacacg gagtcaaaaa cgctgagagt aaaaaatata tacagccttg
    12001 taggtaaagt accacagggc tgtatatttt ttatttcaga ttaccttaaa tgattccatt
    12061 tactttttat ctcatttttt cctactagtt agtatcaaat actctcctat tttctcaata
    12121 aactattttt ggatacatgg tatctgaaac agctaaaacc ttgtcattac agcaaaaaat
    12181 cacgttatcc agactgtaga caaagtccat tttatggatg at
//
LOCUS       DAFLWQ010000086        12162 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.089, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000086 DAFLWQ010000000
VERSION     DAFLWQ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12162
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.089"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(59..1042)
                     /gene="istA"
                     /locus_tag="L1V16_002351"
                     /pseudo
     CDS             complement(59..1042)
                     /gene="istA"
                     /locus_tag="L1V16_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311512.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            complement(1437..2279)
                     /locus_tag="L1V16_002352"
     CDS             complement(1437..2279)
                     /locus_tag="L1V16_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBN1276671.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGI
                     PYINNLGLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQH
                     LEIS"
     gene            2604..3020
                     /locus_tag="L1V16_002353"
     CDS             2604..3020
                     /locus_tag="L1V16_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBN1276672.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            3017..3487
                     /locus_tag="L1V16_002354"
     CDS             3017..3487
                     /locus_tag="L1V16_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1276673.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            3501..4274
                     /locus_tag="L1V16_002355"
     CDS             3501..4274
                     /locus_tag="L1V16_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1276674.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAASPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            4288..5100
                     /locus_tag="L1V16_002356"
     CDS             4288..5100
                     /locus_tag="L1V16_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1276675.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            5154..6119
                     /locus_tag="L1V16_002357"
     CDS             5154..6119
                     /locus_tag="L1V16_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1276676.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            6256..8979
                     /locus_tag="L1V16_002358"
     CDS             6256..8979
                     /locus_tag="L1V16_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1276677.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESQILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGGSIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            8992..9624
                     /locus_tag="L1V16_002359"
     CDS             8992..9624
                     /locus_tag="L1V16_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBN1276678.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            9829..10056
                     /locus_tag="L1V16_002360"
     CDS             9829..10056
                     /locus_tag="L1V16_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011837604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HBN1276679.1"
                     /translation="MLQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEV
                     IPENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            10125..10391
                     /locus_tag="L1V16_002361"
     CDS             10125..10391
                     /locus_tag="L1V16_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBN1276680.1"
                     /translation="MLVQMMNGGRIMSQSTITFRIPDDEKELVLEYAKAHNSSLTELY
                     RNAVLDKIEDEIDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            10381..10650
                     /locus_tag="L1V16_002362"
     CDS             10381..10650
                     /locus_tag="L1V16_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBN1276681.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
     gene            complement(10829..12130)
                     /locus_tag="L1V16_002363"
     CDS             complement(10829..12130)
                     /locus_tag="L1V16_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBN1276682.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT         3972 a         1972 c         2387 g         3831 t
ORIGIN      
        1 aataaatagt ttttctatca agtatattga actacgataa atttgttatt ttgttttgtt
       61 taatttcgtt gtacttattg gctttgactt cgatttcttt aaatactggg taatcggtgt
      121 ccggcaaagc tagcaaatct gttttttctg tgttccatag atcattgata atgacatgtt
      181 tttcgtaatg gattcgctct cgatcgtgtg acagctccac cgctaatgcc tcgttgaaac
      241 tggcgaaatc cttcataatc ggtgtagatg aaaagaagtt gtaccgtaca tagccgactt
      301 tgttttccat actacctttc tcgtttccgc tacgtggatt gcacacctgt gtctcaaaac
      361 catagtgcat agaaaatcgg aggaaaccgt cagtcagcac cgcttgttca gtctttgttt
      421 ttgtctaagt aacggccgtt gacatattat caatccgtat tttccgagga acgccacctg
      481 attggctgaa gagttctttc atgccttcca acaaacattc ttgattctcg gcggggagta
      541 caacggcgaa tcctgcatta ctaaaaggga aagtcatcac taataccttc acatctttaa
      601 acgctccatc gtgacaaact tccatcgtac caaaatcaag ttgcgcttct gctggcgggt
      661 gttcaagacg ctcaaagcct tggtcttcca gtgtttccaa gtagtgtgtc gctttccaat
      721 cttgaatgaa tacacagact gttcggtagg atcctggaaa gccatcggct tttaaagcag
      781 tagtcattgc ttcagcagtc ctacgctttt tatttggcag cttagcatct tctgaaagcc
      841 atagggaaac gatgcctccc cacttttctg tatacatcat accagtcttt ttgcgtgctt
      901 taggttgcgg cagcaaatca tcatctgcat attttttagc cgtgcgccaa tttacatcta
      961 gctcctttgc aatatgatta atggatttat catgattatt tcgtaaattt ctgatagtat
     1021 taatatcggt cattgtgagc atacctttct tacctccagt tacagtgtcg agactataac
     1081 tttagaggag tttcaggttg cccgcaatgg ctttttatct taacttaatc gatttgcgga
     1141 gttgtgtagt ttttcgttgc acttgtatgt acttttattc tgccataaac agcttaatga
     1201 atgtccactt gaaaaagtga ataaacgaaa tagatgactc gatttaataa ggaagtaaac
     1261 ccacacagaa atataggtga ttttccttga atgaccaaga tattgaaagt tagtgaaaaa
     1321 acacaaaaag gtagccctat tcacagaagg tctgcctttt gtgttatcgc cagcaaacat
     1381 tagagggggt atttcatata gcttttgtcc tctcgacagt cctatcagtt tctcttttaa
     1441 cttatctcta agtgctgtcc agttttaata gcttctagct tgtttcctaa ctgtgttttt
     1501 aatatgttga aggcttttga acctgtgcag tggcaagtaa ggattttttc tactcgtgag
     1561 tcattcaatt tatttccaat tttcattacc tcttgctcag gtagacctaa attatttata
     1621 taaggtatgc caatcatatg gaagccacca attaggtatt ttatgggttt agtcggaaat
     1681 gtttcaagag caatttccat catatcgata atgccatgat gactacagcc agtaaagaca
     1741 atcagaccgt cttcttgctc aattacgacc aataattcat ctgaaaaatc atcataaaca
     1801 aatttatcat ccatcttttt gtataaattc ttggtggtcg agtttgcttt gcctaggggg
     1861 atgatatgga agctcggagc aagttctgtt ttcgttttta ttgtatgtaa attctcatgc
     1921 attttaagga tttcattttt aggaatacca acatacagaa acgtggttaa aatctttaaa
     1981 taatggggta aagttacacc ttcagctgta taaatagggg cgtttcctga ttttaaatat
     2041 cttaacccgc cggtgtggtc agaatgaccg tgtgaaataa tcactgcctc cagatcattc
     2101 aaagtttccc ccattttagt cgcattatag actaattttt tattagcgcc agcatcgaag
     2161 agatatttct tccctgagta gttaattaag agagataacc catgtccact tttaaagttc
     2221 aaatttattc ttgagttttc aaataaaacc ttgatttcca ctataacatc tcctttcaca
     2281 tgaacgtgta ttcatatatt gtagcacatt aagttctatt ttttgttgta attaccgaaa
     2341 aaaatattaa tggacgcttt ttacgcttta tttcgtatgt ggaagaaaat ttcttaggat
     2401 gtggcggggg attggggcaa agctaaattc caattacagt gatcatttaa ttagacacct
     2461 ttaaataccc acactttcat caacactata atttagggaa agaaaagtgt tggcatgata
     2521 tagaaaaacc tttaattaac agcgtttcct aaaattggca cgcatcttgc ttatagaaaa
     2581 gcgtaaggat aggaggaatg aaaatggcaa ctataattct tgccagccat ggggaatttg
     2641 ctcaaggatt aaagcaaaca gcgacaatga ttattggaga tagtgtacca attcatgcct
     2701 tgtcagcatt tagagatgaa gatgaatcta ttttggtaca aataaaaaaa cttttagcca
     2761 caatagatat agaagaaacc tacattttaa ctgatattct aggtggtagt gtgaataatg
     2821 atatgctcac tattattaaa gagtatgagg gattgcaatt aattactgga atgaacttac
     2881 ctttagttat ttctattgca acctataatg gaaaaattgg ggaaagtgag ctagaaaagc
     2941 ttattaaaga gagtcaacaa tcagtgattg attgtagaaa attattagta gaacaactta
     3001 ctggaggaga tgacctatga ttaagttagt acgtattgac catcgtttgt tgcacggaca
     3061 ggtagtattt tcttggagta aatcattaaa tatcaatcgt attattattg ccaataaaga
     3121 ggcagcgaat gatgaattca aaaaaatgtc tttgaattta tctaaaccga ctggcattaa
     3181 attaacaatt ttttcagttg aacagttact agaaaaaatg cctaaaatcg aaacacttaa
     3241 cgaaaatatc atgcttattt ttggtaatac aaaagaaatt cgtcaatttt gtgaagccta
     3301 tcctaaagta caagaaatca actatggagg gataatcaaa aaagaaggtt ccaagcaatt
     3361 tagtaatgcc attttcttga atgaatctga gcaagaagat gccaaaaaat taaaagctct
     3421 tggcattaaa caatttattc aacaggtacc aacttctaaa aaagaagatt tgaatacaat
     3481 gttataaagg aggaatgaaa atgctcgttc agtcaattgg tttagggtta atcggtgttt
     3541 tttgtatttt agactcaagg cttttaggaa gaatgaattt tgaacgaccg ttgattgtca
     3601 gtacgcttgt tggtttggta cttggagaca tggaaaaagg attaattgtt ggagcctctt
     3661 tggaattgat gtccttagga ttagtaaata tcggagctgc ttcaccacct gatatgaata
     3721 tggcatcaat tattgctaca gcctttgcca ttttatcaaa tgcgaatgca gaagcagcat
     3781 taacgattgc cattccaatt tcagtgttag gtcaaatact aggtatctta atgcggacga
     3841 ttttgtcaaa tttgactcac gttgcggatc gctttatcga acaaggaaaa tttagccaag
     3901 caaggagaat tcatatactt tatggctcgg gattatatgc tctcatgtat tttattccta
     3961 tttttctagc aatttatttt ggaacgaatc ttgtttctca gattgttgat gcgattcctg
     4021 agtggctaac aaatggctta acggttgcaa gtaaaatttt accagcatat gggtttgcgt
     4081 tgttattaca aacgatgtta acgaaaaaaa tggtgccatt tttattactt ggatttttaa
     4141 ttactgctta ttctggattg ggaatcattg gtattgcagc cttcgcatgt attgttgcgt
     4201 ttgtcatggt tcaagttcaa ggtaaaaact caaatggtaa ccaaaatgag ccagatccat
     4261 tagatgactt ataaggaggt agattaagtg aaagagaaag atcaaaatgc atggaaatat
     4321 cggcagttct tatggcgttc atgggcaatt caagcctcat ggaactatga acgacaaatg
     4381 aacatgggtt ttatgtacgg aattgcacca attctagata acatttacaa gaatccagaa
     4441 gatgaagcaa tgaagaaaga agcttacgag cggcatatga tgtactacaa ctgtacccct
     4501 caaacaagtg catttgtgtt agggttaact gcttctatgg aggagcaata ctacgaagac
     4561 caagaaaact ttaatccgga atcaatcagt gcagtgaaga cttctctgat gggaccgcta
     4621 tctggtgttg gtgattcttt ctttcaagga acgattcggg tattagcctt tggactagga
     4681 attaatttag cccaacaagg tagtatttta ggtccaattc tagcaatgtt aatttccttt
     4741 gtaccttcct ttttagttac ttactatggt gggaaaattg gctataacat ggggaataaa
     4801 tacttgtcta aactgtatca agaaggtttg atggataaag taatgtatgt ttgctccatt
     4861 gtggggttga tggtcattgg ttcgatgatt gccagcatga tcgggattac aacaccaatt
     4921 caaatgggta aagcttttgt cttacaagat gtattagata gtattatgcc acaattttta
     4981 ccattaggat taaccttctt catgtactgg ttattgcaga aaaaggtcaa aacaggatgg
     5041 atgttggcaa tctgtttagt cggaggaatt atttttagtt tgttaggtat cttacaataa
     5101 gggaataacc aataaatttg gttgaataat ataaataagg aggaattcaa ttgatgaatt
     5161 caaaagaaat tgttaaagaa atcgtagcga aaaaagaggt aaaatcaatc gtatttgttg
     5221 gctgtggcgc ttcaaaagcg gacctttatc ctgcaaagta ttttctagac caaaatgcga
     5281 agcagttacg gattagtcat tacacagcca gcgaatttaa ctatgcaaca ccagcatctg
     5341 tagatgagtc aactgtcgtt atttcagctt ctttaggagg tacgactcca gaaacagttg
     5401 aagctaacgc agtagctaaa gaaaaaggtg ctacagttat tagtctaaca cgaagcattg
     5461 actcaccgtt aacaaaagat gcagattatg taatttatca tcgatttgca gagaactatg
     5521 ctgctaaatt agaaaaaaca ggctactgtt tagaattggc agtagaactt ttacatcaag
     5581 tagaaggtta tgaccattat gaagcaatgc aagaaggatt tgctactatc tatgatcttg
     5641 cccaaaaaag tgcagaatca gctcgtaaag atgcgaagaa atttgctgaa cgctttaaag
     5701 atgaaaaagt tatttatgta atgagtagtg gtgctacaca tgaagtagca tactcaacat
     5761 caatttgctt gatgatggaa atgcaatgga ttaattctgg taccttccat tcaggagaat
     5821 ttttccacgg accattcgaa attgtggata aagacgtacc gtttatatta ttaatgaatg
     5881 atggaaaaac tagaaatata gatgctcgag cattaacttt ccttgaacgc tttgatacga
     5941 aaacagaagt tgtagatgcc ttggattatg gcttgtcttc acatattgct aaagaagtct
     6001 tagactactt taacccattc gtgattactg cagtatttag agtttatgca gaagaattgt
     6061 cagaagcaag agaacatcca ttaactaaga gacgttatat gtggaaacta acttattaaa
     6121 aaatagatca aactaaataa ggtggcttga gaaattaagc caccttgttt tcttcaatgt
     6181 gattttatac atatggtaaa ataactagta catatggtaa aataactagt acatattgtg
     6241 aaagcaggtg gcaagatgca gcgattaaat gactatcttt atcaactaac attgcttttg
     6301 aaatctacgc cttcagataa ttattcagct cgcagtattt cgcaagctct acagttgaat
     6361 agaagtacaa tcagtagcta cttaaatgaa ggtgttcgtg aagggctttt cataaaagta
     6421 aaaagttacc cggttttatt tttacataga acagctcttg aagaactaca tatcacactg
     6481 aataactccg aaatagaatc aattgaaagc ttgttaacaa tttctcaaaa acccgcatta
     6541 gatcaagtaa ttggctctaa aggaagtttg aaagaagcaa ttgatcaaat taaaacggca
     6601 gtcttatatc ctggaaaagg gttgccttta ttattgatcg gcgctagtgg atcagggaaa
     6661 acctttctag cgaataaaat atatgaatat gcagtagaag aaaaggtcat tcacacatcg
     6721 gcacctttca tagattataa ttgtgcacaa tatgtgagca atccagagtt actatcctct
     6781 gctttatttg gctacacgaa aggagcattt accggagcaa gccaggagca tactggtttg
     6841 ctagaaaaag ccgatggagg agtattgttt ttagatgaag tgcatcgctt atctgaagaa
     6901 gggcaagaga aattatttac atttatggat acgggtgaat tctctcctat gggggataat
     6961 agtattcgga aaaaagccga tgttcgatta gtctttgcaa caacagaaaa tatatatacg
     7021 actttcttac caacttttct taggagattg ccagttattg ttaatctacc tagatttcaa
     7081 caacgtccgt cgtttgaacg tctgtcattg attgatgaat tttttgtttc tgagagccaa
     7141 attttagcta aggaactatc tgtttctgat gcattgattc atttcttaat gaatagtgat
     7201 tttgaaggta acgtggggaa tattaaaaat attatcaagt atgcttgcgg aaacgcatat
     7261 atccaccaga agagtcagca aacaattcaa gttaaattat tggatatgcc tttagagtac
     7321 agttataaat tcaaggagca actaaataaa cccagaaaga aaagagcaga tcgaatctac
     7381 tatccagaag aaacacgaca agtgcaacta gaaagaaaca atcagctttt tgttcaattt
     7441 tttgaccaat tacttactgg attctctgaa gtgattgaaa ataacaagga tattaaacta
     7501 tttttagaag aaatggttac caaggtaaca caagtaatgg atacgcttat ttttcaagag
     7561 gattacgaaa aagagcagtc tttatacgcc attctaaact atcatattcg tcaaagtatt
     7621 gattttatgc gagaaagcta cgggtttgaa caagatggta accgggtagt cgctttggcc
     7681 aactatctat atgtcaagga taatcaagtg atttttgaaa atagtcttca agaaaagaaa
     7741 accaaagatc agcttaacga attttttgct aatgttcttg aaacccctta ttggtatgca
     7801 aaaaaaatct taagcctttt atctgagtgt ttagatcaac ctgtgtatga agaggacatt
     7861 ttctttatta cgctatattt ttatagtttg aatgtcacga atgttaaaac aggtattaag
     7921 agtattgtgc tagctcatgg ttattctaca gctagtagta tggcgaatgt tgccaaccgt
     7981 atgctgaata agaacgtttt tcaagcttat gatatgcctt tagatattac attagagaaa
     8041 attgaagcaa aattgattca attccttgga gattatcgaa cagattcagg cttgatttta
     8101 ttggtagata tgggttcact aaaccaacta ggcggtttat tagtgaatca tctaaatgga
     8161 ccactgttaa tcattgatca tatcaataca ccgttattat tggaagtcgg ccaacaagta
     8221 ttaaacaata aaagtatcac cgaaatagga gcagaaattg aaacaagtct tactttcaaa
     8281 aagcagttac tacttcccaa gaaaaagaaa aagaaagcca tcattacttg ttgttataca
     8341 gggattggta gtgcgaccca gattcaggag attttaacga aatgcttgaa agatgcagtt
     8401 agagaattag taattattcc gtatgattac aaaaagctgt tagaaaacaa gaattttgag
     8461 actccttttc aattatacga tgtcatcatg attgtaggta cagaagatcc caaaattaat
     8521 cagattccat atattggatt agatcgcctg attaatgggg gaagcattgg cgaatttgtt
     8581 cattacttgg aaaaagagct gactattgaa gtgaacgatt tacaaaaaga attaattttc
     8641 aatttttcaa ttagtaaaat tgtcgaaaat ttaaccattt tggatccaga taaggtgcta
     8701 tcttttgtac aaaaagcaat taaagaatta tcgaagttat taaattttga tttttctaat
     8761 aatcagctgt ttttgttgta ccttcactgt agttgtatga ttgaacgaat tgtacgtaaa
     8821 gaaagtgtgg atgagcaaga ggacattgaa gaatatatgc aagcaaatgg agaaataatg
     8881 gataaaattc atagcgcttt ttttgagatt gaaagggaat acacaattga aataccagat
     8941 ttagagttgc gattattgag cgatattgtt caaggatagg agtgaattcg aatgacaatg
     9001 ggagtaattt ttgatatgga tggggtactc atagatagcg agacatttta ttttgagaga
     9061 agaatgaact tctttcaaga actggagata gatccaggat caaaccagat tgatgattat
     9121 gtggggaaaa cagaagctgc aatatgggaa acattagttc ctgaggacaa atcattaaga
     9181 gaggaacttt atccgaaata tgtagattat cgaaaaacgc atccaattga tttcgctaaa
     9241 gctttacgaa aagaagtgaa accgttactt gacttcctca agaagcggga tataccattg
     9301 gcactggcat cttcttctcc agctgtcgag atagagagta tgctcattca atgtgaactt
     9361 actgaatatt tttcctttgt tataagtggt gagtcattaa aacaaagcaa accacatccc
     9421 gaaatatatt taaaagcgaa acagcaatta gactgtgact tctttattgc agtagaggat
     9481 tcaacgattg gtattaaatc agcaaaggca gcaaatatct atacggcggc actaaaacaa
     9541 ccaatgcaaa tcgatcagag tgaagcagac atacaaattg aaagtctaca agaactggaa
     9601 caaattgttt tagaaaaagg ttagtgaatt aatggaaata aggctatata tctgtgctag
     9661 ctattttgac taaccaaaaa aacttgctat aattcaggtg tagtaaaagg tgctggtaac
     9721 accttttacg aaaatgcttc ggcagtgata atgggattgg ctttttaagt tttttatttt
     9781 gttcgcaatc cctaaggtca tgtgaatgat cctagggatt gctagaatat tttgcaacag
     9841 aaccaaaata cgaatagtta tcaagcagcc atattgactg cggtcaattt aggaggggat
     9901 actgatacta ctgctgccgt aactggtgct cttgcgggta ttctttacgg gggtgaagtg
     9961 atccctgaaa attggagaaa atcgcttcaa aatgaccagc ttcttaaaac gatcagtcag
    10021 agattttgcg ataccgtgct atctcaaaga atttgaataa tggatatgat gcaaatcttg
    10081 tttgtactaa cgttgtattg acaaaaagga ttttatttag tacaatgtta gtacaaatga
    10141 tgaacggagg tagaatcatg tctcaatcaa ccattacatt taggattccc gacgatgaaa
    10201 aagaactggt attagaatat gcaaaagcac acaattcttc attgaccgaa ctttatcgaa
    10261 atgctgtact ggataaaatc gaagatgaaa tcgatctacg gactttacgg agtgcaattg
    10321 aagtttccaa agagaaaaaa gagagtggta tttctcaaga ggaaatggag aaactgctaa
    10381 atgaattata aagtcatcta catgccgcaa gcccagaagc aattaaaaaa aatggacaga
    10441 aaccaagcta aaataattgt cgcctggatc agaaagaatt tagaaaacac gactgacccg
    10501 cgtcagcacg gaaaaggttt gactggaaat aagagtgggg aatggcgcta tcgaattgga
    10561 aactatcgaa tattggctaa tatttgtgat tctgaaattg aaatccagat attctcaatt
    10621 ggacatagaa gtacaatata taaaagataa ccgtttttgg aacgaagtag agtttcgaaa
    10681 gtcaatgtat aatcttttga attttgcata ataccacagg tagaaactac ccgatactat
    10741 cggttggttt ctgctttttt atggctcttt gtcaaatagg actgatagag tgagataaga
    10801 acatctaagg tagaattcct tttctacttt agatgttttt tgattcatag gtaatcagat
    10861 tatttagtaa gaaaattctg gtcttcattt tccgaaagct tcgaaagcca taagcgactc
    10921 gtttcaatgc tttgatgtgg gtatgcagat tttctatttt ggcatttgaa taaggcaatt
    10981 cgagggctaa acgaatgccg gattcatagt ttataaaagc tttttttata gaatgcagtt
    11041 cttttggaac ggaattgggc atcgttctta caagtttaaa gaaagtgtcc gcctctttgt
    11101 cgtgaaacgc ttgaagaatt tcttgatagt aaaaataggc gattcgtaat tcgtcagaga
    11161 tcgaaagcag acgatccacc acttcacttt cggtgagata cgcccaacca aaattgcgcc
    11221 atttggtcca tttgtcataa acaagcttgt cctgtcgttt gatcagaagc cgagacaacg
    11281 cctttaattg tcgataatat ttggcttgtg ttggatcgtt tcgatcaaag cttttcatga
    11341 ttcgtacgcg aatatcctca aatttacgaa tgagatgttt gacaatgtga aaacgatcca
    11401 caacgagttt tgcctttgga aaacattcct ttatcagaga ggcataagaa acattcatgt
    11461 ccgtcacgat gacctttacc ttcaatcgtg cgcgtcgttc aaattgcata aaataagaaa
    11521 cgagagcctt tttcttccgt gaaggaagaa tatccagtaa ttttccagta tcgccatcca
    11581 tacaagaaaa ggagtaggga ccgacttgat ttttcagtga acgaaattca tccattaata
    11641 aacaacgcgg taaccaattt ctttttactt ttgtcatggg gatcagagaa gcgagtgtcc
    11701 gagaaacggt cgaccaagaa acgccgcaat gcttagcaat tgtcgtcatt gcttgttttt
    11761 cagttagctc ttctaaaatt ttatagcgca cttgtttagc gataaagcag tttctatcga
    11821 caatgtaggt attcgccgta aaataggtgt ggcagccacg acagtggtag cgttgtttcg
    11881 ctaaagcaag ataagtcagt tggttcgcac atttattaag ttgaatgagc gattttttct
    11941 ttccgttctt aacgatcatg ccttcatgat tcatctgttt acacaaagga cagcgacgaa
    12001 tttctttact taacgtcgca gaaacaacaa gactcttgat attcttaatg ctcttcgatt
    12061 ccacatttgt gatgaaaatg tttttatctt tgattccaag tagtagtttg atatgatgaa
    12121 gatcaggcat acagaacgct cctttgattg tgttgtggtg at
//
LOCUS       DAFLWQ010000087        11805 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.090, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000087 DAFLWQ010000000
VERSION     DAFLWQ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11805
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.090"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(192..569)
                     /locus_tag="L1V16_002364"
     CDS             complement(192..569)
                     /locus_tag="L1V16_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276683.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(869..1750)
                     /gene="galU"
                     /locus_tag="L1V16_002365"
     CDS             complement(869..1750)
                     /gene="galU"
                     /locus_tag="L1V16_002365"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBN1276684.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(1793..2812)
                     /locus_tag="L1V16_002366"
     CDS             complement(1793..2812)
                     /locus_tag="L1V16_002366"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBN1276685.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            complement(3445..4449)
                     /locus_tag="L1V16_002367"
     CDS             complement(3445..4449)
                     /locus_tag="L1V16_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1276686.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            complement(4462..5511)
                     /locus_tag="L1V16_002368"
     CDS             complement(4462..5511)
                     /locus_tag="L1V16_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1276687.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            complement(5528..6349)
                     /locus_tag="L1V16_002369"
     CDS             complement(5528..6349)
                     /locus_tag="L1V16_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1276688.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            complement(6336..7115)
                     /locus_tag="L1V16_002370"
     CDS             complement(6336..7115)
                     /locus_tag="L1V16_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1276689.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            complement(7132..7602)
                     /locus_tag="L1V16_002371"
     CDS             complement(7132..7602)
                     /locus_tag="L1V16_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1276690.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            complement(7614..8033)
                     /locus_tag="L1V16_002372"
     CDS             complement(7614..8033)
                     /locus_tag="L1V16_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBN1276691.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            complement(8114..10891)
                     /locus_tag="L1V16_002373"
     CDS             complement(8114..10891)
                     /locus_tag="L1V16_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1276692.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            11082..11306
                     /locus_tag="L1V16_002374"
     CDS             11082..11306
                     /locus_tag="L1V16_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276693.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
BASE COUNT         3430 a         2481 c         1911 g         3983 t
ORIGIN      
        1 aaacattggt atgatttata tatatataaa taacataaaa aaaggaatgg cttatcccga
       61 tacaacaagc attcctttaa aaaagattct tttatataag tgaaaaaagc ttttttccac
      121 caattaaata aatctctcat ctcaatagtt tatccattat tttatctttt tttgcgtata
      181 cctactaaat attaccgtct tcttctcgtt cttctacttt gttcgagaga atctgtacta
      241 gaaaaagtag ttgtatgtct accttttctg cctatccgag actttctttt catatatggg
      301 atataaatga ttagatacag tacagcaaaa aataaagcaa atacgcaagc ttcccaacta
      361 cctaacgcca attcaaccat caaggtagca accccaacgg atgctgcata ccagataaaa
      421 atcagaaacg tttctttttt tctgaccatg cgaaacatga taaatagact aataagcaat
      481 agtggcaaca caaatatcca attgcttcct tccatcagcc acttgagtat atcaagcagc
      541 gactgtgcaa cagcgactaa ttttcccata gtgaacacac accttttttt ataattaaaa
      601 aattcgcctt tttattctac tatgaatctt ctggcttggc tttcatttct cttatgtaat
      661 cattttcttt tatacaactt aaaaaaaaat taaaccatta gcataatatt ttctgaatct
      721 attcacgaaa gtctttttct atctttcgtt ttccacgact caactgatct agagtcaaaa
      781 aactaaaacg acagttgcgc aaatgacgca caagctgccg ctttaataac aaatagcctt
      841 tcattctcag caggccactt atttccagtt aactttctgt tcttagcttt ttactcaact
      901 ggataatata tgcacttaat gaagtcccaa tttccgaatg ttgaagtcca tattcaatat
      961 ttgtcttcat atatcctaac ttatcgccta cgtcgtatct ttttccttta aactctctcg
     1021 catagaccgc ctctgtctgg ttaagagtct gaagtgcatc cgttagctgt atctcgtttc
     1081 ctgctcctgg ttcttgagtt tctaatatct caaatatttt aggagtcagt agataacgtc
     1141 cgataatggc taaattactt ggtgcttttc ccatttcagg tttttctaca aaccctttta
     1201 ctctgcaacg acccttttcg ctatctgttt taggatcaat aattccgtat ttagatgttt
     1261 cattttctgg tacacgcatg acggcaacag cggaagcttg tgtttcttca taatccatca
     1321 tcaattgttg agtcaatggg atatcatctt tcatcaaatc atcccccagc atgacgacaa
     1381 acggttcatt tcctataaat gcttttgctt gaagcacggc atcccccagt cctcttggat
     1441 gagattgacg gatgaagtga agattgactt gagtcgtttc ttcaactaaa gcgagtaatt
     1501 ctgttttttc cttttcccgc aaattgtttt ccaattcgat atttgcatca aagtgatctt
     1561 caatgggtct tttttctttt cccgttacga tcaagatgtc ttcgattccc gaatccaatg
     1621 cttcttccac aataaactgg atcgttggtt tatccacgat tggaagcatt tcttttgcca
     1681 tggcttttgt tgccggcaaa aaacgtgttc ctagcccagc ggcaggaatg actgcttttt
     1741 tgaccttcac ttgctgttcc tcctaaacga cgattaacta ttgatcatct atttaacgaa
     1801 gagaaaattc attctccatt tttccgtcac gtaacatgat ttcttttgct gcttttttga
     1861 tatcttctcc attatacaaa acattataga ttgtttgagt aattggcatc tcaacaccta
     1921 gctgttgagc tagctctact gctgcttttg tcgttgccac accctcaacg accattccca
     1981 tgttttctag aacttcttcc agcttatgtc cctgtcctaa caagttaccg gcacgccaat
     2041 tgcgagaatg aacacttgta caagtaacga tcaagtcccc cacaccactc aaaccgataa
     2101 atgtcagagg attggcaccc atcgcgacac caagacggct gatttctgcc aatcctcgag
     2161 tcatgattgc tgcttttgca tcatctccga atcctaatcc atggatagcg ccggcaccaa
     2221 ttgcaatgat atttttcagt gctgcaccag tttctacgcc aatcacatca ttatttgtat
     2281 aaatcctgaa ataatcattc atgaacagtt tttgtacata ggctgctgct ttttgatcaa
     2341 tacttgcagc tgtaattgtt gtgatatcat gtactgccac ttcctcagca tggctaggac
     2401 cagataatac aacaattgcc tgtctttttt cttctggaat ttcttcagcc aaaacttctg
     2461 agattcgttt atgcgtatct tgttctagtc ctttacttgc atgtataatg attggcttag
     2521 tattcatttt accaataagt tcctgtgcga ctgaacgaat cgcttttgtt ggaacaacaa
     2581 ataaaatagc atctgcgtta tccactgctt ctgccaattc tttatatccg ataatcgatt
     2641 ctgggatcgt caaatcaggt aaaaaatgct gatttgtatg atacttattg atttcatcaa
     2701 tctgttcagg tacatttccc caaatacgga catcatgccc gttttctgcc aatgtttgtg
     2761 ctaaagcagt gccccaagat ccaggaccaa gaactgcgat tttttgtttc atggatattc
     2821 ctccaaataa ataattgata atttccatta tagtatacat ttcttaaagt tgggactaat
     2881 ttccattgtt tttaagtgtt tgtttacttc ttttatcgtt tttacttgaa ataatcaatg
     2941 atatgttaca atagtctaca ttttattttt acactcgtta tgctttgctt gttcctaaga
     3001 ggaagcagtt ttgacaatgt tactaccagc attactatta ggaggttagg aaacttctcc
     3061 tagtgagtat tgatttaaaa tacataagag acagattgaa catttctaaa tctgtcaggt
     3121 cctgcaacgg acagattgtc tctgttgacg gttgacatag gaacttttgt tttagtcaac
     3181 attctggata caaaacgcta tgtaaactgg cgcaactcgt tgtacttgga cttttactac
     3241 ggatccatgc aacaactaaa tagtactatt gcataacaaa aaatggttgg cacccacatg
     3301 tcccattaaa cagattataa gttgaactgt agataatgca aaaaatgtgt tttataacgt
     3361 aattgatgcc aatattttaa aaaaataaag ggagcagtta tcgctgctct ctttattttt
     3421 tatattcttt ttatccagtc tatcctaata atcaaactga cgatagtagc ggcgtatctc
     3481 taatggatgg cagttcaact gctccacatg agcatcgatg cgttgtgtca ctacatgcat
     3541 caataagaaa gacaaaacac gtccgcgata tttttcactg ataccttcta ctggatagtc
     3601 ttttgtgtct atcaatgtat aattgctgca aatttttggc aaaagtttag ccacacgttc
     3661 agataacact ctctgttcat cttcgcctaa aaataatgtg actggggttg tttcttctac
     3721 gatctctaac gtcccgtgaa gaaactcggc agcatggata gatttcgatg gaagccagct
     3781 ttgttcttcc cagtaacaca tggcatatga ataaacagct ccccattgat tccctgctcc
     3841 aataaaataa tgcatactat cacgtcgatg tttttctgca aatgataagc caaatgcatc
     3901 tgcttttttc tctgcttcca ctaaccctgt tggtaaataa cgttcgagct gttcatagta
     3961 ttctgaataa gcttcgaatt ctccattcaa atacatcaat cgatctgctg ccataaaaaa
     4021 tttgatttgt tctgttccag gagctggata agtgaccaca aaatcgcata gctgagacaa
     4081 cttactgttc gctttatcga taaatccaat cagtgtcgct cctactttct tgatttgttc
     4141 tactgctttc actacttctt gagttgtacc ggtaacagag gacaaaataa cgatagaatc
     4201 ttttgttaat cttttgtttc cagtagtgta atattctgca gcatgctgta caaagacagg
     4261 caagttgctt ttcccattca tataagtgac agcttgcatc gaggaagcat acgttccacc
     4321 gattcctaga taatagacag cgtcaaattt ttccgcataa agtttatcga tgatttcttc
     4381 tacttgcgga cgtaaagcta gtgcgccttt tattgctttg atttgttctt cttcattgaa
     4441 tttcagcatg atttccacct cttataattt acttttcaag actgtatcaa agtcttcaaa
     4501 aatctttttg ttcaagtcaa tacctttagc tactgcggtt ttataagcga atagttgaaa
     4561 cggaacgaca agcgctaata cagacagata ttcatcacat tctattgcta atccaagtgt
     4621 tttctcgttt cttgcttttt ttgtggtaat ggtgagagtc tctccaacgt accgactcat
     4681 atatctttgc aacttttgcg aacgttcctt atttacactt tccccttcaa taaagaatag
     4741 caaatgcgaa gcatctgcct ccaggtatgg gccgtgcata taagcttcta actcaaatcc
     4801 ttgtgacgga acgcggattg tttcagtcaa tttcgtctct gcttctttag ctgttcccca
     4861 gtttggacca tatccaatgg tgacgaaacg ctgtgctaaa cgaaataaac tttgatatcc
     4921 atcaaaaaat tcttccgttt tttgaataat cgctggtaaa tggttgatta ttttgcgcaa
     4981 ctgttgcatg tagtcttgtt ctattttttt gctgatttta tttttactta ttccaattcc
     5041 tatccctaag agtagtaact gtaaaacagt cgcagaatag ccttttgtaa cgaagcctac
     5101 tgattctacc ccggcaccta aatcaataat ttgtgcagct tctaaagcaa gtggactttg
     5161 cacgtcattt gtgatagcaa caacaggtaa cccttgtttt tgtatcattt ttactgcttc
     5221 aacagtagaa gcacttttcc cgctttgtga cacagcaatc acagtatcga ttgaaggaga
     5281 aagttttcca taattgaaaa aataaaaagg ttcttgaata tcgacagtaa gatcaccata
     5341 agattccaat gctggcttcg ctgctaaaca agcgttataa gatgaacccg ttgctaagat
     5401 cagtaaattc actgtttttt tcatatgttc tcttgtcgaa aaatcattct ttttcaagat
     5461 cgtacttagt acttcctttt cttcatagat ataatcttgc atcgtaaaca ttttctctgc
     5521 tcctttttta aaaaatccct atccacgaac caaaaattcc aaagaaagct agtccgatca
     5581 agatcgttaa tggtttcact tctttcttca atagataaaa cactatgcca aatgctccaa
     5641 gacataagat atttggaacg atatcatcaa aaatactttg aacagtcaca gcattttctc
     5701 ctgaaccgat ttttaaagga atattgatgg tgatcatcgt ggcagtcatt gctccaacga
     5761 ccatcagtcc aataatagac gcgcctaatg tcaaactttc catcataccg tttgcctgga
     5821 tctttttcaa aaaacccgtt cctaagcgat atccccaacc tgttgctaga tagcgaaaca
     5881 gaatgtgcgg aatattgaaa atcaaaatga acaagatagg gcctaaaata tttccttgca
     5941 tggctaaaga ggtacccaca cctgtggcaa tcaatcgcaa agttccccaa aagaaagaat
     6001 ctcctaaccc tgcaagaggt cccatcaaag atgttttgat actatcgatc gcagtcacat
     6061 caaattcagg atcatcctta ttttcttcct ccattgcagc cgtgattcct aaaatcagtg
     6121 taacgatatg tggggtcgtg ttaaaaaact ctagatgccg tttcaaagct gctgccattt
     6181 cttctttcga ctgatataac tttttcaaaa tcggaatcat tgcataaaca taagccatat
     6241 tcatctgacg ttcataattc caagaaaact ccatttgaaa agaacgccaa aatacgtgat
     6301 ttagctcttt tttcgttatt ttgctgtttt tgatctcaga attcttcatc ttcttctacc
     6361 tcccctgcag ttgtttgaag tggtagttga cggacattca taatattgac taccacaact
     6421 gctaaaatcg caccaaaaat agctactccg gtcacaggaa tctctaagta agaagctata
     6481 gcaaaaccta agaaaaaata tggtgcaact tgtttgttga tcagcaaacg agcaagcatc
     6541 gcaaaaccaa gagctggaat caaccctgta gctactgaca accccttttg aacgaagtca
     6601 ggaatcatat ttaatagatt tccgatcgta ttgcttccca ccatataaga aaccattacc
     6661 acaacaccaa gcatcaagga aagaccgata ccggcaagca agtgcatatg ctcgactcct
     6721 ttataatttc cttcttctgc ataattgtct gctttatggt tcataattgg aatcaaaagc
     6781 cctaagtaaa tatttttcaa tatcaatgtc aacgtagcaa tcggcaaacc tagtaaaagc
     6841 gcggtttctg taccggctcc agctgtaata gcaaaagccg tccctaaaat cccaccggtc
     6901 acaacatcag gtggaatcga agcacctact gagaacgatc cgataaatgc taactctaaa
     6961 gttgcgccca taatgatccc agtttttaca tcacctaaca cgattcctgt aaacagcccc
     7021 gtcacaatcg gacgagaaag caacgatgtc cctagtgcat attctgattg tgcgacaaat
     7081 gcaacaattc ctaataagac tgcttgtaca atcattgagg ttcttccttt cttacaaaac
     7141 ttctcttaca tccacttttt tatctgctgg tacttgacgg atttctactt ctatttgttt
     7201 gtcaattaat cgtttcaagc gttcctcctc ttctggtaaa atatttaccg cttttccgat
     7261 gctgcgagta ccaggttttg ccttgatccc tcctaagttg atggttttga tttctggata
     7321 cgcttctgcc agcttatatg catcctcgat cgattccact acgatgaata acttatattt
     7381 atctgtcacc ccgcttttca acgcggcaat cgagtcatca attgatttga tcactagttt
     7441 gactccttgt ggcttggcta atttgatcgt tgtctttcgt atctcattcg taggtacatc
     7501 atcattagca atcaaaatac agtctgcgcc tattgtttgt gtccatgaaa aagctacttg
     7561 tccgtgtaat aaccgatggt cgactcttgt caatacaatc atttttcttc ctcctaaaat
     7621 tcgtcttctt ctattttctg attgagccgc tcgttacaaa actggatcat tttttttgaa
     7681 tcagttagca cctgctggat caaaacagtt gtctctactt cagcgtccaa ccgagatact
     7741 agctcaatca atagtggcaa attcaatccg gcaacgagat agacatgatc ccgattgata
     7801 tattgtaaga attcgttgtt gacacttccg ccaaaaagat ccgtcagaac aatgatttct
     7861 ttatctttgt acctcataaa aagctgcctt actgtttccg ctaaatcaaa attctcatca
     7921 gtatagcaat cgaatacagt aatagaatga tttttcccat agatcagctc taatgaatct
     7981 aatatccctg aagcaaattt tccatgggaa gctaagataa tttctctatc cactttttca
     8041 tctcctcttt tcacttacac atactaaaaa agcaagttgc atgccaaaat tagtggcaac
     8101 aacttgctta tgttcaaaat tcttcttcta tcgagagaaa ctctgtatct tcactcaaaa
     8161 tatcatagat ataggcaatc tcagaattgg ggatcatgac actataatgc tcttcaatga
     8221 cactaaacgc agatttaata gcagataacc cttctttttg acactgcttc catttctcta
     8281 atccttgata ggtttcgatt ggcatttgtc ggatcaatcg ttcaatgaga cagctcacat
     8341 ggacatacaa cgctaatttt ttgggattgc tgatgcttcg attcaactgc acctctaatt
     8401 ctctcataaa atgatcgatt tctcccatca ccttctctgt atctagaata gtcacggaat
     8461 ccagtacttt ttccaatgaa aaattacgaa tgatgcgctg attgaatatt tccttctctg
     8521 aagcattcat agtagtgtcc aaccattcag ctagtacaga catcttttcc cccgagatga
     8581 ggtcttctaa tgaaagatag tcgatattgg tgatatcagg atctgtggtg ccaatcattc
     8641 ctacgacttc gtatatggaa aataatgggt cactgttttt cttatctttt aattgctgat
     8701 attcatatgg gatgattttc aactgacaag ccgtaggtaa gcttttttct agcagttcac
     8761 ttaagtggac cgccgtaccg attccagtga agcaagtagt aatgagtgct ttgggtttgt
     8821 tttcctctgg atagagcagt cgccattctg gctggatctg tcgaacagtc tcttctgcta
     8881 tctcttctaa tgatacattt ttttgcaggc attcccctac tgtgattgct aaaggtgtcg
     8941 tcacattatt caaaatcaaa agcggtacgg ataactgttt tttaaaaaac tgatggattt
     9001 ctttcagaga tcccatgtct actaatatga tcaatccatt tgaaacatcg ctgttttcgc
     9061 aataatcaag gatttctgaa gcaatctgct gtggtgtgac atctagtggc atatcaaatg
     9121 attcaaatag atcctcttgt aataaacgat ttactacatt tgccatactg ctagcagttg
     9181 cataaccgtg agcagcaatc atcgcttttg gcagtcgttt ttcttttgac catttcgctt
     9241 tttttagata gatcgtcagt aaaatccgat ccatacttgt gtcttcaata tctaatttga
     9301 tcttacttaa ttccagaatt cgttggacat agtgataact agatggataa gactgagaaa
     9361 cttgttgttc taattctttg attagttgga taatatcatg ttcttccggt aaccatttga
     9421 tagtgcttcg ctgatagaga tagtaactca aggcatagac actgtttcca tcgaatttga
     9481 tttgataggc agtttccatt tgtcgaaagg tctctcggat agattgtgtc caataaacca
     9541 gcagctcgtg tttttcttgt ctactggtct caaacagcaa aaaatcaaat aattgaatca
     9601 cttcttgctt taattttcct tcgcaagaat atagcagaca gttatttttc ttgaaatcaa
     9661 ttaggatttg ctcaaaactt ttaacgattc gctgctgttc gggctgttgc ttctccatta
     9721 attgctctaa ggtctggtct tgcgtaatat agattccttg ctgtgctgta tttttagtaa
     9781 taggctgcgc aagtagttct ttttgcaaat gatggatcgt gacatggatt tcaggctgtt
     9841 cacgctgttc agcatatgct tttgctgctg aaactttgac gatatttttc agctctccta
     9901 tgtttccgga taatttctga cttgttaaaa gtgacaaagc tggtccactg actgacaaag
     9961 ggctccccat ttttctttgt tcttcgagaa aaaaagagta aatcagttct agccgttcat
    10021 tacgactacg ctgattaagt gcaggtagtt cgattcggat aggtattctt cgaatgaaag
    10081 ttgttaagaa atgactagta atctcttcag tcgtagcaaa aaagagacgt gttttgatcc
    10141 ggcgtgacaa attaggttct cccatacgat aaatcacacc ttgatcaaga taggtgaaca
    10201 gtttttcctg accttctggt gttaagcgat gtacctcgtc taaaaacaag atcccaccat
    10261 ctgctgcttc aaaagcccct tttttatttt cttctgcacc agtgtacgct cccttaacat
    10321 gtccaaacaa attgctagtc aaaagttcag gattatctgc atattgtgca caattaaaag
    10381 tgatgaatgg tgcagaatct tctagcagat catgaagcag acaatactga tagaccaaat
    10441 taactaaata acttttacct gtgccacttt cgcctgtaat caaaagtggt aatccgccat
    10501 ctggatagta aagagctgtt ttgatttgtt cgatactttc tttcaaactg gcgtcgtatc
    10561 cgatcataaa agagaataag tcttttggtt gcgcgaaaaa aggctgttcc tctttgagat
    10621 catcgataga aaaataaaaa ttcgtgcgta acttaaaaaa ttgtttttca aaagcttctt
    10681 tgtggaaata aatcactggt cgagaattga ttttgactag tagttgctca tcatttaact
    10741 ggttcaaata atgactgact gtgtttcttt ttaccccaaa atgatcagct aacctttgtg
    10801 ctgtaaagac ctcgttcata tgttctaaat cgaaaaaggc tgtctggttc tctaagtaac
    10861 ataaaatttc cttcttcaac aacttattca cccctcctcc atcatagaaa acggattcat
    10921 tttgtcaata aaatctttaa taaagaattg aaaaatatat cttattatag acagcagcct
    10981 acttatccct tataattttt attctaaaaa acgtacagtt ccttccagtt tttatactgg
    11041 aatttcaaca tatgaaagaa taaggaggct atgactattc aatgaaatcg gataaatata
    11101 aaaacaggaa acatacttcc tggaaaactt ttcgagaaat catcggatct tatctcgctg
    11161 tagttgtatt tttgcctttg ctttatatgg ctatgacaga acaaactcgt tttattggcg
    11221 tagatacgca atatatagcc gaaacaggat ttttattcat ctttatcttg atttttgcgt
    11281 tctataaatc cttccataca aaataagatt cacagatttc aactttcctg tctgttttta
    11341 gctattacaa atccttatat gtggtataac aacaatttat tggcataatg aggaaaaacg
    11401 agttatgatg ctttcagaga gtaaagaggt actgttgtca ccatcctttt tattgattac
    11461 gtacaccact cttagttttt tcccattgat tacgaaaaca aggtagaaac attgatgttc
    11521 ctaccttgtt ttcttttttt attttcagat caaaatctca agtggctttt gacttgatgt
    11581 cgggaggttg tcttcgttcc atcaaacctg atagaatctg cgccaaacca tagttttctc
    11641 cactattatt tattcctcta agatagtacc cacaataaac gaataaatat ttttctcatt
    11701 ttcatactcc ttctttgaaa atcaattaga tttctctcaa cccacttttt tacaaaaatt
    11761 acgtagcaaa aaagattgca agaacaaatt aaaaaagaag taaat
//
LOCUS       DAFLWQ010000088        11599 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.091, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000088 DAFLWQ010000000
VERSION     DAFLWQ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11599
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.091"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            6..305
                     /locus_tag="L1V16_002375"
     CDS             6..305
                     /locus_tag="L1V16_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1276694.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="L1V16_002376"
     CDS             378..1739
                     /locus_tag="L1V16_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBN1276695.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="L1V16_002377"
     CDS             1761..2021
                     /locus_tag="L1V16_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276696.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="L1V16_002378"
     CDS             2035..2787
                     /locus_tag="L1V16_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBN1276697.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="L1V16_002379"
     CDS             complement(2881..3486)
                     /locus_tag="L1V16_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1276698.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="L1V16_002380"
     CDS             complement(3539..4513)
                     /locus_tag="L1V16_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HBN1276699.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="L1V16_002381"
     CDS             complement(4891..5610)
                     /locus_tag="L1V16_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1276700.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="L1V16_002382"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="L1V16_002382"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBN1276701.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="L1V16_002383"
     CDS             7161..8558
                     /locus_tag="L1V16_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1276702.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="L1V16_002384"
     CDS             8639..9079
                     /locus_tag="L1V16_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBN1276703.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="L1V16_002385"
     CDS             9227..9553
                     /locus_tag="L1V16_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBN1276704.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="L1V16_002386"
     CDS             9554..10303
                     /locus_tag="L1V16_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276705.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="L1V16_002387"
     CDS             complement(10383..10838)
                     /locus_tag="L1V16_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBN1276706.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="L1V16_002388"
     CDS             complement(11265..11540)
                     /locus_tag="L1V16_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276707.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
BASE COUNT         3659 a         2013 c         2357 g         3570 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaag
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaa
//
LOCUS       DAFLWQ010000089        11347 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.092, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000089 DAFLWQ010000000
VERSION     DAFLWQ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.092"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..760
                     /locus_tag="L1V16_002389"
     CDS             <1..760
                     /locus_tag="L1V16_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1276708.1"
                     /translation="FEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNGVSLARKP
                     KTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELISLTES
                     DYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLIKNNKDK
                     YIFISKNGNPISIQAYNQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPLKAIMD
                     RVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
     gene            complement(842..2614)
                     /locus_tag="L1V16_002390"
     CDS             complement(842..2614)
                     /locus_tag="L1V16_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1276709.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(2617..4329)
                     /locus_tag="L1V16_002391"
     CDS             complement(2617..4329)
                     /locus_tag="L1V16_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1276710.1"
                     /translation="MKLILRHAKKYKVSVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            4444..5112
                     /locus_tag="L1V16_002392"
     CDS             4444..5112
                     /locus_tag="L1V16_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HBN1276711.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            complement(5179..5967)
                     /locus_tag="L1V16_002393"
     CDS             complement(5179..5967)
                     /locus_tag="L1V16_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBN1276712.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(6050..7522)
                     /locus_tag="L1V16_002394"
     CDS             complement(6050..7522)
                     /locus_tag="L1V16_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1276713.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            complement(7652..8845)
                     /locus_tag="L1V16_002395"
     CDS             complement(7652..8845)
                     /locus_tag="L1V16_002395"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBN1276714.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     regulatory      complement(8843..8922)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            complement(9111..9182)
                     /locus_tag="L1V16_002396"
     tRNA            complement(9111..9182)
                     /locus_tag="L1V16_002396"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9147..9149),aa:Glu,seq:ttc)
     gene            complement(9194..9267)
                     /locus_tag="L1V16_002397"
     tRNA            complement(9194..9267)
                     /locus_tag="L1V16_002397"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9231..9233),aa:Ile,seq:gat)
     gene            complement(9280..9350)
                     /locus_tag="L1V16_002398"
     tRNA            complement(9280..9350)
                     /locus_tag="L1V16_002398"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9316..9318),aa:Gly,seq:tcc)
     gene            complement(9355..9427)
                     /locus_tag="L1V16_002399"
     tRNA            complement(9355..9427)
                     /locus_tag="L1V16_002399"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9392..9394),aa:Phe,seq:gaa)
     gene            complement(9431..9503)
                     /locus_tag="L1V16_002400"
     tRNA            complement(9431..9503)
                     /locus_tag="L1V16_002400"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9468..9470),aa:Asp,seq:gtc)
     gene            complement(9522..9595)
                     /locus_tag="L1V16_002401"
     tRNA            complement(9522..9595)
                     /locus_tag="L1V16_002401"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9559..9561),aa:Met,seq:cat)
     gene            complement(9608..9697)
                     /locus_tag="L1V16_002402"
     tRNA            complement(9608..9697)
                     /locus_tag="L1V16_002402"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9659..9661),aa:Ser,seq:tga)
     gene            complement(9720..9791)
                     /locus_tag="L1V16_002403"
     tRNA            complement(9720..9791)
                     /locus_tag="L1V16_002403"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9756..9758),aa:Glu,seq:ttc)
     gene            complement(9813..9900)
                     /locus_tag="L1V16_002404"
     tRNA            complement(9813..9900)
                     /locus_tag="L1V16_002404"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9864..9866),aa:Ser,seq:gct)
     gene            complement(9925..9998)
                     /locus_tag="L1V16_002405"
     tRNA            complement(9925..9998)
                     /locus_tag="L1V16_002405"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9962..9964),aa:Ile,seq:gat)
     gene            complement(10012..10082)
                     /locus_tag="L1V16_002406"
     tRNA            complement(10012..10082)
                     /locus_tag="L1V16_002406"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10048..10050),aa:Gly,seq:tcc)
     gene            complement(10084..10159)
                     /locus_tag="L1V16_002407"
     tRNA            complement(10084..10159)
                     /locus_tag="L1V16_002407"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10124..10126),aa:Asp,seq:gtc)
     gene            complement(10178..10251)
                     /locus_tag="L1V16_002408"
     tRNA            complement(10178..10251)
                     /locus_tag="L1V16_002408"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10215..10217),aa:Met,seq:cat)
     gene            complement(10264..10353)
                     /locus_tag="L1V16_002409"
     tRNA            complement(10264..10353)
                     /locus_tag="L1V16_002409"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10315..10317),aa:Ser,seq:tga)
     gene            complement(10377..10450)
                     /locus_tag="L1V16_002410"
     tRNA            complement(10377..10450)
                     /locus_tag="L1V16_002410"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10414..10416),aa:Ile,seq:cat)
     gene            complement(10464..10537)
                     /locus_tag="L1V16_002411"
     tRNA            complement(10464..10537)
                     /locus_tag="L1V16_002411"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10501..10503),aa:Met,seq:cat)
     gene            complement(10565..10637)
                     /locus_tag="L1V16_002412"
     tRNA            complement(10565..10637)
                     /locus_tag="L1V16_002412"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10602..10604),aa:Ala,seq:tgc)
     gene            complement(10657..10730)
                     /locus_tag="L1V16_002413"
     tRNA            complement(10657..10730)
                     /locus_tag="L1V16_002413"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10694..10696),aa:Pro,seq:tgg)
     gene            complement(10740..10813)
                     /locus_tag="L1V16_002414"
     tRNA            complement(10740..10813)
                     /locus_tag="L1V16_002414"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10777..10779),aa:Arg,seq:acg)
     gene            complement(10824..10909)
                     /locus_tag="L1V16_002415"
     tRNA            complement(10824..10909)
                     /locus_tag="L1V16_002415"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10873..10875),aa:Leu,seq:taa)
     gene            complement(10926..10997)
                     /locus_tag="L1V16_002416"
     tRNA            complement(10926..10997)
                     /locus_tag="L1V16_002416"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10963..10965),aa:Gly,seq:gcc)
     gene            complement(11009..11081)
                     /locus_tag="L1V16_002417"
     tRNA            complement(11009..11081)
                     /locus_tag="L1V16_002417"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11046..11048),aa:Thr,seq:tgt)
     gene            complement(11099..11180)
                     /locus_tag="L1V16_002418"
     tRNA            complement(11099..11180)
                     /locus_tag="L1V16_002418"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11144..11146),aa:Leu,seq:tag)
     gene            complement(11188..11260)
                     /locus_tag="L1V16_002419"
     tRNA            complement(11188..11260)
                     /locus_tag="L1V16_002419"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11225..11227),aa:Lys,seq:ttt)
     gene            complement(11264..11336)
                     /locus_tag="L1V16_002420"
     tRNA            complement(11264..11336)
                     /locus_tag="L1V16_002420"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11301..11303),aa:Val,seq:tac)
BASE COUNT         3493 a         2558 c         2025 g         3271 t
ORIGIN      
        1 ttttgaaaaa aatttatcat ataattatgt aatacattta aaaactttta caggaatgat
       61 ttttaaattc gccaaccgtc gatatggatt aaaatataat cccgtaaatg gggtttcttt
      121 agcaagaaaa cctaagacaa acgaagaaat aaaaaaagaa aaagatggtt atttatcaaa
      181 agaagaagtt caaatgattg ctagtaaaca aaaaagttca catcaacagt cacgttattc
      241 tttaattact aaatttttgt ttttaactgg actacgttat ggtgaattga tatctttgac
      301 tgaatctgat tatgatggta ataaaattac ggtttctggt acttatgatt acgagttaaa
      361 aattaaaaca acaactaaaa atacaggttc ttatagaacc attgaattat caagtaatgc
      421 taaagaaatc atagatcaat taattgaaga aaacaaatta attaagaata ataaagataa
      481 atacattttc atctctaaaa atggtaaccc gatatctatt caagcatata atcaatcttt
      541 aagagcagta tccaaagaat taaacctaga taaaaaagtt tcttctcaca tgttaaggca
      601 ttcccacatt tctctactta cagaattagg aatcccatta aaagccatta tggatcgtgt
      661 aggacatgaa gattcaaaaa caacattaaa gatttatact catacaacta aaaatatgca
      721 aaatcaacta gtagaaaaac taggaaaaat agaaatttaa attgcccctt ttctgcccct
      781 tataaaaaca aacaacataa aatatataaa aagaaccccg ttataacgag gttcttttaa
      841 tttaactttc aaatacaaat tgattatgat aaagttccgc ataaaatcca ttttctgcta
      901 ataactcatg atgactgcct tcttcaatga cttccccatc acgcaagaca acgattctat
      961 ctgcattcaa gattgttttc agccggtgag caatcacaaa gctggttctt cctttgattg
     1021 cttcatccat tgctttttgg atccttgctt ctgttaccgt gtctacatta cttgttgctt
     1081 catccaaaat caataaagat ggatttgtga tgatcgttcg agcaatactg atcaactgct
     1141 tttgacctgt actgaataag ttattttctt cggatatctc tgtatcataa cctttttcta
     1201 acgtcatgat gaagtcatga atattcgctt gttttgctgc attgatgact tcttcatctg
     1261 aagcgtccgg tttgccgaat gtgatattgt ctttgatcgt tccggagaac aatacagatt
     1321 cttgcaaaac gattcctaca tgtctacgta atgcatcaag atcataatct cggatatcta
     1381 ttccatcgat gactactgaa ccatcattga catcgtaaaa acggtttagc agattcatga
     1441 tcgtcgtttt ccccgatcct gttggaccaa caagagcaac catttctcct ttgtccacat
     1501 tgatcgagac atctttcaag actagttttt ctggagaata accaaaatct acgtgctgca
     1561 acgcaagacc tttttcaaca ccatcaaatg ctttaccgtt ttctggtttg acttcatctt
     1621 tttcatcaaa tatttcattc aatcgtcttg cccctgtaat cgctaattgg atcatgctgt
     1681 atccagatga aatctgcatc agtggttggt aatattgttg tgaatactgg acgaatgtca
     1741 caactaagcc taatgccacc gaacgttcca aatcaccatt taatgctaac cagccgccga
     1801 aaaagataac tatcgctgta ttgaccagtg acattccttg catcatcgga aatagtagac
     1861 cagaataagc ttgtcctttg aaggttgctt cgcgaacact ttgattatgc tctaagaatc
     1921 cttcaatcgt ttcttcttgt aagccatttg tgatgatgac acgttgtccg ctgatttttt
     1981 catccatata accatttagt ttccccactt catcttgctg aagatccaca tatttccgtg
     2041 ctttgcggat aatcaagaca gctatcaaaa cggctactgg agtggaagca attgtagccc
     2101 aagctaactc tacattttgg cggaacatca tgatcaagat cccgacaagt aaaacagcat
     2161 tcgtgatgac ttgaagcaaa gcttggttca aactattttg aatattatct aagtcactgg
     2221 taaaacgact taaaatttca ccgtcttgat gagaatcaaa gaaacggatc gtcaattttt
     2281 ccaatttgtt gaatagaccg atacgcattc ggttcgttga cttccctact acttgtgtga
     2341 acaaaatact atagataaag ttggctgcac tagctagtac ataaaacagc aagagtttcc
     2401 atattacaga aacaaatttg cttttatcgt ctacgccttg catcaagcct cctacgtaat
     2461 tagctaattc ttgaaaagct tccccgatgt attgaggtgc ctttacttgt agataggtag
     2521 caatgatcac tgtgataaag ataaagaaaa aggagagttt gtaccgcttc aaatagtgat
     2581 agaaaaattt acttgctttt attagatcag tcatacttac tcctccgttc ctttttgagt
     2641 ttcaaagatt tcctgataga cacggtttcc agctaccaat tcctcatggg ttccttcgcc
     2701 gactaatctg ccttcatcca atactaagat gcggtctgct ttgacaacag aagcaatttt
     2761 ttgtgcgatg acaatcgtcg ttgttccctt caaatctcga tcgagtgctt ctcggaccag
     2821 cttttcagag cgagcatcca gtgcactcgt actgtcatct aggatcaaga tctttggatt
     2881 accgataacg ccacgagtaa tggataaacg ttgcttttga ccaccagaaa agttactgct
     2941 acgttcttct attggtgctt cgtaacgatc agataacttt tcgatgaatt cttttgcttg
     3001 agcaatagaa gaagcatgtt ccatctcttt ttctgttgca ttctttttcc cttggcgcaa
     3061 gttttgagca atcgttcctg agaataaaat tgctttttgc aaaacaaagg aaaccgtttg
     3121 tcttaaactc ttttcattta cttgacgaag atctacacca cctacttcaa ctttgccttc
     3181 tgtcggatca aatagacgag ggatcaattg tgctagtgtt gacttcccgg caccagtcgc
     3241 cccgacgata ccaaccattt ctccaggttt gatagaaaag ctgatatctt taagcgtatc
     3301 tgtatcctca ccaggataac gaaaagaaac atggtcaaaa gtgacagaac ccgtcaactc
     3361 ttgttctgga acgtctaaat aagtaagatc tggttcagca tctaaaattt ccgcaatccg
     3421 cttcagcgat acggctgctc ttgaagtcat catcatcatc attccgccaa taatgattgc
     3481 catcataatc tgcatcaagt agttcatgaa tgaagcaatt ccaccaatta acgtaggatc
     3541 atctttaaca agatcgctca caaaaaagat cgccccaacc acagccaaat tggcagccag
     3601 catgaaggac gggatcatca cagaaaataa tgtaccgact atgatgttgt gttttgttaa
     3661 gtcctcactt actttgctga atgacttcaa ttggttttct tcttgtacaa aagatttcac
     3721 tacacgaatc cctagtaagt tttcttttgc aatgctattc acacgatcaa tcagtttttg
     3781 aatgatcatg aagtgcttgc ccatccttgt aaatgaaagt gccgtaatca gaaataccgt
     3841 aacgataagc gctacgatga tccaccataa ttgcggcatc gtgatcatag ctaaaatgaa
     3901 ggcaccaata aataagaatg gaattcgaaa aagtgattgc aaagaaatca tcactaaatt
     3961 ttggatttgc gtgatatcat ttgttagacg aacaacaaga tttccagcag agaactgttc
     4021 gatatttcca aatgaaaatg tctggatctt tcgaaatgct tcttctcgga tatctgcact
     4081 tacgccttga gctacttttg cagagaaaat cgtgttcgtt acacctgcgg ctaatcctag
     4141 caaagccaga ctgatcaggt aaataccaat tgttttcatt tcatcattat cttctgtaat
     4201 aatagcttcc aatacttgct gtagtaactt aggttgccat aatgctgctg caaccatgac
     4261 tgctacggac agcaaggaaa taaaaacaga tactttatat tttttcgcat gtcgtaagat
     4321 taatttcatt cgttgattac acccctttgt ttaaattgac aggactaatt taacactgta
     4381 aaattagacc gactaacaat ttaccatgtt taaaaagata atgcaataca cgaggttgat
     4441 aaaatggaaa taaagctttc tcaagcaatc atcattcagg ccgcctttga tatcctggct
     4501 gaaacacaag ctctttcgca gctttccatg cgaaacatcg caaacagaat tcatgttcaa
     4561 gcacctgctt tatattggta tttcaaaaac aaacaacagc tcttgcaaaa aatggctgaa
     4621 acaatggaag aagaattagc gcttccagat ccaactttgc cttggaatga acagttgctg
     4681 cagtatatgg aaaattacta tgacctttat acacgtttcc cttgtggggc agaattagaa
     4741 atcaatactg tgcccgcttt tccgagtcga ttagaacatt tggagcaaat gatccaatta
     4801 cttgttcgtg aaggattttc agtcacccaa agtcatcagg ccattgcctc tctccacaat
     4861 ttattgattg gacagttaat ggatcagcag catgaacagc agcttcgaca aaaaattatg
     4921 gacggaaatg aatttttgaa agaaacagtt ctatttatgc gtaattatgt agttgaaaat
     4981 caattagagg gatttaaaga aagtatgcag tcccatgcag aattgaatga aaaagcactc
     5041 tttctaacga gtgcacaaac ctatattgaa ggcttatgcc aacaaaataa aagaagagaa
     5101 aacgagcagt aaaaaagctc ctatagagat cactatgttt gtgatctcta taggagctat
     5161 ctttttaaga ctcttttttt atttttcttc cattagccac gccaatgcac gttgaatcca
     5221 ttggtcccag aagatccagt tatgatcgcc aggtccttgt tcaaaggtga ccgccaagcc
     5281 ttgttcctgc atagcagata ccatttcctg atttgcctga taaagaaaat cagattcccc
     5341 acaagccata taaaatcttg gaactggttt tccgcttttt actagttctt tcaataagta
     5401 ttgcggatca ttttttgaac cttcgatttg atccaatggt ccaaagatcc cttcccaaaa
     5461 agatgcttta cgaaccatca aaagatcatc cattcgattt cctacagaaa cagcgcctga
     5521 aagagagatt actgctgcga aattttctga ttttgcaagg cctagtttta acgcgccata
     5581 tccgcccatc gataatccag cggcatatgt tttttctctt tttcttgtta attgcgggaa
     5641 taattcatga caaatctcag gtagctcttc tgcaatgaat gtccaatact tcatgtcata
     5701 aactgtatct gtgtaccagc caagatcagt agatggcatg atgacagcta atccgtagtt
     5761 tgctacataa cgttcaatcg acgtacgtct ttcccataca ctatgattgc cacccattcc
     5821 atgaagtaaa tataaaacag gtatatccgt tgtctcttgc tctgaactgg tgccaatcac
     5881 cttttttgtt gtttgcggta gtatcacatt tagattgact tccatttcta acacattcga
     5941 ataaatattt gcttgaataa atgccatatt ttcgccttcc ttagtaagaa gttatttttg
     6001 aataacttta aatttgaatg attcggctac gtacatatct taaccgaaac tactgtttta
     6061 ttttaccact tttttcatga acgaaaagcg ttaagaccaa agcaatgatc acgagtaaca
     6121 agccaactag ataaacggaa tgtaacccat cataaagaat ttttcttaat ggtaacaaaa
     6181 tatccgcatc aatatattta gccgtttgtg gattcaccag tttattcatg atatctgcat
     6241 catttgttaa atttgctgct gcaagttctc gtttagttac cccatttatc aataaaccaa
     6301 aaatagaaac catgactgtt tgaccaattg ttcgaactaa cgtattaaaa gaagttgcta
     6361 caccaagctg gtcacgagat acactatttt gtgcactgac agtcgaggta gtcatggtca
     6421 cacctaagcc tataccgatg accgttgata tagcaaaaaa ccataaatag ttacttctga
     6481 aaggcataag atacaaccaa gcgcccccaa tagctgcgat tagtagtcca attctcaaga
     6541 cccaatgagt tttcatttga gtcatccact tgcttgcaag gaaagaaccg accatccaga
     6601 ctagtgataa tggtgctaat accagcccac caattgctgc attcagccct aatacacctt
     6661 gcatccacat agggatataa acatcgattc ccatcaaaaa accactagcc aatgctgcag
     6721 ccaagttgac cacaacaaat agtggatttt tgaataaatg catcatgatg acaggatctt
     6781 tagctctttt ttcggcaaaa acaaaaatac ctaacattac gatactacct agcagcaaag
     6841 cagaaacaag cggactcatt ccttcgtctc ctaataattg gaaccctaac agcaatgaga
     6901 caagcatggc catcaaacta aaactaccaa aaatatccat tggtttagac tcatgtatga
     6961 tttttggttc atttaaatat agccaaatca aaataattaa tagaattccg atcggcacat
     7021 tgataaaaaa gatccagtgc cagctgatcg tttcaacgat gaatcctccc gcaagcggtc
     7081 caaaaacact ggcaatcccc caggctgaac tattcaaacc taaaactttt gctcgctttt
     7141 caatagaata aagatcgccg atgatcgtca aagctactgg catcattgcc ccagcaccca
     7201 tcccttgaat cgcacgagca gcaatcaacc caatcatgct ttgagataaa ccgcaaaata
     7261 acgaaccgat aataaacaat aatgtcccaa aaataaagat tggtttccgt cccactttat
     7321 ccgcaagttt tccgtaaatc ggagtaagca tagcgtttgt cagcaaataa atcgaaaata
     7381 cccagttcat gatttccatt ccatgtaatg aaccgacaat cgttggcata gcggttgtta
     7441 cgattgtacc ttcaatagcc gtcatgaacg ttgcaatgaa aatactcact gtgaccaaag
     7501 taacatttgt ttcttttttc atcttattcc tccctttcat tatgacagga tctaaaaata
     7561 gataaataat tactatcttt ttcaagaggt taactgccat aaaaaaagct ggaacaacca
     7621 ccacttggcg atcgttccag ctgaatataa cttattttgc taaacttgct ttcaacgcat
     7681 ctactttgtc cgtatgttcc caaggcaaat ctacatctgt acgaccaaaa tgaccgtaag
     7741 cagctgtttg tttgtaaatc ggacgacgca aatcaagcat ctcgatgatt cctgctggcc
     7801 gaagatcgaa gttttctctc actgcagcaa tcagttcttc ttccggaacc gttccagtac
     7861 cgaaagtatt gattgagatc gaaacaggtt gagcaacacc aatcgcataa gctagctgta
     7921 cttctgcttt gcgagcaagc cctgctgcaa caatgttttt agcaatataa cgtgcagcat
     7981 agctggcaga acggtcaact tttgtcgcat ctttaccaga aaaagcaccg ccaccatgac
     8041 gagcataacc gccatacgta tcaacaatga tttttcttcc tgttaatccg gcatcccctt
     8101 gaggaccacc aatgacaaat cggccagtcg gattgatata atatttcgtt tgatcatcta
     8161 ataattcagc tggaataact tccttcacta ctttttcgat gacatcatga cgaattgttt
     8221 cattatctac tgcatcatca tgctgtgttg aaataacgat tgtatctacg cgttccggtt
     8281 gtccttgatc atcatattca accgttactt gagattttgc atctggacgt aaatacgtta
     8341 attcatttga tttacgcaaa tctgccaagc gtcgtaccag acgatgactc aaagcgattg
     8401 gtaaaggcat caattctggt gtttcatcta cagcaaaccc aaacattaaa ccttggtcac
     8461 cagcaccaat ctcatctaat acgtcttttt tatcttcatc ccggatctca agtgcttcat
     8521 caactccttg agcaatatca ggagattgtt catcaatcgc aaccaataca gctgctgtat
     8581 ctccatcaaa tccgaatttt gcacgtgtat aaccaatttc ttttattgtt tcccgtacga
     8641 ctttttgaat atctacatat gccgtcgtag atatttctcc aaatactaaa acaagaccag
     8701 ttgttacaga cgtttcacac gctactcgtg ctgttggatc ttgttttaaa attgcatcca
     8761 agattgcatc actgatttgg tcagcaattt tatctggatg tccttcagaa acagattctg
     8821 atgtaaataa gtgtctttct accattataa tgattccccc tagttaaatt cggttacaag
     8881 gcatctccgt cctgcggatc ctttcgggaa cttgcaacga accaagtata gcagataaaa
     8941 cagttttctg ctcgtatttt ttcatttttt tgcttaaaaa atataaaaat attttacatt
     9001 agaactgtcc aaaaaagctt agcacaatca tccataaaga taactctgct aagcttttta
     9061 aaatcattct ttcagataaa aagaaaaaga tactcaaaaa gtatcttcca tgacccgtac
     9121 gggattcgaa cccgtgttac cgccgtgaaa gggcggtgtc ttaaccgctt gaccaacggg
     9181 ccaataaaat aaatgggcct aaatggactc gaaccatcga cctcacgctt atcaggcgtg
     9241 cgctctaacc agctgagcta taggcccata aaaactaaaa gcgggtgacg agaatcgaac
     9301 tcgcgacaac agcttggaag gctgtggttt taccactaaa ctacacccgc ataatggcgc
     9361 gggacagaat cgaactgccg acacatggag cttcaatcca ttgctctacc aactgagcta
     9421 ccgagccaaa cggttccgac gggaatcgaa cccgcgatct cctgcgtgac aggcaggcat
     9481 gttaacccct acaccacgga accaatgttt ttagttttta attgcgggag caggatttga
     9541 acctacgacc ttcgggttat gagcccgacg agctaccaga ctgctccatc ccgcgataat
     9601 atgaaaaagg aggataaggg attcgaaccc ttgcacggtt ttacccgcct gacggttttc
     9661 aagaccgttc ccttcagccg gacttgggta atcctccatg taaaactata ttaaattaat
     9721 gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag ggcggtgtct taaccgcttg
     9781 accaacgggc caggtaaaac aaaatattga aacggagaag gagggatttg aaccctcgcg
     9841 ccggtttccc gacctacacc cttagcaggg gcgcctcttc agccacttga gtacttcccc
     9901 aaaaccaata agattttgta ctaatgggcc taaatggact cgaaccatcg acctcacgct
     9961 tatcaggcgt gcgctctaac cagctgagct ataggcccat aaaaaactaa aagcgggtga
    10021 cgagaatcga actcgcgaca acagcttgga aggctgtggt tttaccacta aactacaccc
    10081 gcatggcggt tccgacggga atcgaacccg cgatctcctg cgtgacaggc aggcatgtta
    10141 acccctacac cacggaacca gtgtttttag tttttaattg cgggagcagg atttgaacct
    10201 acgaccttcg ggttatgagc ccgacgagct accagactgc tccatcccgc gataatatga
    10261 aaaaggagga taagggattc gaacccttgc acggttttac ccgcctgacg gttttcaaga
    10321 ccgttccctt cagccggact tgggtaatcc tccatatgaa acttacaacg ccacaatgga
    10381 ccttgtagga ctcgaaccta cgaccggacg gttatgagcc gtctgctcta accaactgag
    10441 ctaaaggtcc aggctcttaa aaatcgcggc ggaggggatc gaacccccga cctcccgggt
    10501 atgaaccgga cgctctagcc agctgagcta caccgcgaaa aagatattca ttatttaaat
    10561 gaaatggagc ctagcgggat cgaaccgctg acctcctgcg tgcaaagcag gcgctctccc
    10621 agctgagcta aggccccgtg tttaaattta taattatcgg gaagacagga ttcgaacctg
    10681 cgaccccttg gtcccaaacc aagtgctcta ccaagctgag ctacttcccg tttaattaac
    10741 gcgcccaaga ggagtcgaac ccctaacctt ttgatccgta gtcaaacact ctatccagtt
    10801 gagctatggg cgcatatttg aaatgccgag gaccggaatc gaaccggtac ggtgatcact
    10861 caccgcagga ttttaagtcc tgtgcgtctg ccagttccgc caccccggcg cgattgcttt
    10921 ggcaaagcgg aaaacggggt tcgaacccgc gacccccacc ttggcaaggt ggtgctctac
    10981 cactgagcta tttccgcgtg tttaaagatg ccggctaaag gacttgaacc ctcgaccctc
    11041 tgattacaaa tcagatgctc taccaactga gctaagccgg catgtaaaac ttaaattatg
    11101 cgggtgaagg gacttgaacc cccacgccgt aaggcgctag atcctaaatc tagtgcgtct
    11161 gccaattccg ccacacccgc aaaaatatga gccgtacagg gctcgaacct gtgaccctct
    11221 gattaaaagt cagatgctct accaactgag ctaacggctc atatggaggt taacgggatc
    11281 gaaccgctga ccctctgctt gtaaggcaga tgctctccca gctgagctaa acctccatgg
    11341 ataactt
//
LOCUS       DAFLWQ010000090        10909 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.093, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000090 DAFLWQ010000000
VERSION     DAFLWQ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10909
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.093"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            93..1352
                     /gene="lysA"
                     /locus_tag="L1V16_002421"
     CDS             93..1352
                     /gene="lysA"
                     /locus_tag="L1V16_002421"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBN1276715.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            1339..2139
                     /gene="dapF"
                     /locus_tag="L1V16_002422"
     CDS             1339..2139
                     /gene="dapF"
                     /locus_tag="L1V16_002422"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBN1276716.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            2142..3023
                     /locus_tag="L1V16_002423"
     CDS             2142..3023
                     /locus_tag="L1V16_002423"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBN1276717.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            3020..3736
                     /locus_tag="L1V16_002424"
     CDS             3020..3736
                     /locus_tag="L1V16_002424"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBN1276718.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            3742..4437
                     /gene="dapD"
                     /locus_tag="L1V16_002425"
     CDS             3742..4437
                     /gene="dapD"
                     /locus_tag="L1V16_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBN1276719.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            4453..5454
                     /locus_tag="L1V16_002426"
     CDS             4453..5454
                     /locus_tag="L1V16_002426"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBN1276720.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            5451..6812
                     /locus_tag="L1V16_002427"
     CDS             5451..6812
                     /locus_tag="L1V16_002427"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBN1276721.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            6772..7923
                     /locus_tag="L1V16_002428"
     CDS             6772..7923
                     /locus_tag="L1V16_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBN1276722.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            7898..9067
                     /locus_tag="L1V16_002429"
     CDS             7898..9067
                     /locus_tag="L1V16_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBN1276723.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            9242..10621
                     /locus_tag="L1V16_002430"
     CDS             9242..10621
                     /locus_tag="L1V16_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBN1276724.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
BASE COUNT         3620 a         1906 c         2443 g         2940 t
ORIGIN      
        1 aattttgttt aatattattc caataaaatt caaatcttta tcaaatgaaa ttccaataaa
       61 aacggaaaaa aagtgaaaag aggaatgaaa aaatgacaga attgataatt ggcggagtca
      121 cagcaagcac attggcagaa aagtataaga cacctctgta tgtgtatgat gaagaaaaga
      181 tgagacaaac gatgctgtca ttcaagcgag gctttgtatc gaaacgtttt gatacaaaag
      241 tgctttacgc ctctaaagca ttccaaacga ttgagatgct gcatttagtt cgtgaatatg
      301 gattcgggct agatgttgtc agtggtgggg aaatctatac cgctttgcaa gctgattttc
      361 ctagagatac tatctacttc catggtaaca acaagacgcc agaggaactg atctatgcac
      421 ttgaaaatga tttgttgcat attgttgccg ataatttgat ggaagttgaa ttattagcag
      481 aattaagcca acgctattta aaaaaaatct gtatcatgct tcggttgaat gtcggagtag
      541 aagcacatac tcatgaatat atcgtcactg cgcatattga ttcaaaattc ggcatgagct
      601 atgaaagtaa agagtgccaa caagcccttc agttgataaa agaaagcagc tatctagagt
      661 tagaaggatt tcatgctcat atcgggtcac aaatttttga tgttactgct tggttagctg
      721 aaatcgacaa attgacgaat tacttaaccg attttgacca acctctttcc ttgaatcttg
      781 gcggagggtt tgggattcgt tatacacaaa atgatcagcc gatcccagtc gaagaggcac
      841 taaaaaaact gattgaatat acggaagaag ctttggaaaa acgaaaactg accattcgtc
      901 aattactgat cgaaccgggt agaagtattg ttggagaagc tggtacaaca ctatacacga
      961 ttggtttcat caaaaagaca ccacataaaa aatattactt tgtagatggc gggatgacag
     1021 ataatatccg tccagctctg tatcaggcag aatacgattg tgatttagca gcaaaactgt
     1081 cggaagaaaa aacagagaaa gtgacgattg caggaaaaat gtgtgaatca ggcgatgtgg
     1141 taattaaaga agcttatttg ccgaaagcag aatcgggtga tcttttagct gtttattcca
     1201 cgggagctta tggatactcg atgagcagca actacaatcg agcgacacga ccagcagttg
     1261 tttttgtcaa taatggccaa tcaagactga ttgttcgcag acaagcattt tctgatctac
     1321 taagggggga agtttcctat gatccttcat aaatataatg gctgcggaaa tgattttatc
     1381 ttattagatt acgcagaaga cacagattat agtcaattag ccgcttcttt atgcacaaaa
     1441 gaaaaatatg atatagacgg attgatcgcc gtaaaaatcg atccgttgga aatgatctat
     1501 tacaacaaag atggcagccg cgcgccgatg tgcggaaatg gcattcgctg ttttgctcga
     1561 tacgtaaatg atcagaacat gatgaatgaa caggaattca acgtagagac attagcaggc
     1621 acaagaaaaa ttacggtgtt ggatccctca cctttttatt gcagcgtaga tatgggagtg
     1681 ccagatgatt ctccggaaaa aatcaaagct aatcaaactt atccaataaa aaaccaggaa
     1741 atagagatca atggtgaaaa agtaacgatc actagtttat ttttaggaac gattcatacc
     1801 gttgtttttg ttgaaaatgc gcgtgaggaa gtctggagaa aaagaggtga actgatctgt
     1861 catcatcctt tgttcaaaga aaaaaccaat gtcaactttg tagaagtagt caatgaacaa
     1921 gaattgatcg tccgtaccta tgaaagagga gtaggttgga cacttgcttg cggtacaggt
     1981 tgctgtgcct cttatgtggt tgctaaggaa actgggaaaa tttcagcaga tcaggtagtt
     2041 gttcacttgg aacaaggaga cttgatgatc tctggtgagg atgcgataca aatggctggc
     2101 ccagcagttc atgaatggac aagaatattg gaggaatgaa gatgataaaa ggttcgatcg
     2161 tggcgctgat cacgccgatg aatgaagagg gatcagtaga ttatgctggt ttggaaaaat
     2221 tgatccaatt ccatttagat gaacaaacag atggattatt agttttaggt acaacaggag
     2281 aatcttctac gctcacacaa tctgaggagg agcagatcct tcaactgaca gtaaagaaag
     2341 tggctggccg tgtgccggtg attgcaggag ctggaacgaa taatacgaaa gaaacgattg
     2401 aaaaagcgaa gcattttgct tctttggggg cagacgcact tttggtcatc accccttact
     2461 acaacaaaac aagtgatgca ggactagctg ctcattttac agcaattgca gaagcctcac
     2521 cgattccgct tattttgtat aatgttcctt ctagaacagg catgtcgatt ccaatccatg
     2581 tattagtaaa tttagcagaa catcctaata tcattggttt gaaagaagcc tcaggagata
     2641 tggcttatgt gatggatgcc gctcggttga ttggagaaga attcttcctt tacagtggaa
     2701 atgatgattt gatcctacca gtaatgagtg taggaggaag cggtgtaata agtgtatggg
     2761 cgaatatcca acctaaaata gtccatgaat tagtaaaaga tacgcaggac ggaagatggc
     2821 agcaagcaaa agaaaagcaa ttaaatgcac ttgaactgat ccatgccttg ttcagtgaga
     2881 ccaatcctat tcctgtcaaa gcagccatgt cattattaga cttaccttcc ggacctctac
     2941 gcctgccttt agtttctctt tcaaaagaga aaaagaaaca attagctcag cttttgttaa
     3001 aagaaaggac ggttgaaaaa tgaaaatcgg actgattggc agtggacaga tgggaaatag
     3061 agtcgaagaa gttgcacaag aaagaggaga tacggtcctt cttttacgga cggcacctaa
     3121 agaagcaact acgcttgctt ttacggaact gccagaactg cttattgatt tttctcatcc
     3181 agataattta gagaaaatcc tttcgtatag cttatcatat caacttccgt tagtcattgg
     3241 cacgacaggt tatacacaat cacagttcca agaaataaaa gaacatgcca aacatgtacc
     3301 tgtgatgtat agtgctaatt tttcgttcgg catcatggtg atgaatcaac taatcaagca
     3361 agcagctgca atgttgcaag gctggcagat cgaactgatt gaaaaacatc atagtcgtaa
     3421 aaaagatgca ccatctggta ctgcaaatat gctgcttcaa acaatccaag aagtgcaaaa
     3481 gctgcagccc gtatacaact ggcaagggaa aaaaagagaa gaaaaccaaa ttggtgtaca
     3541 cagtattcgt gcaggttctt tacctggtga acatgatgta ttgtttgctg ctactgatga
     3601 aatatttacg atcaaacatg aatctttttc taatcgaatc tttgctgcag gcgcagtaga
     3661 agcagcggac tggttgaaag atcagtcacc aggttattac aaattagaag atttattaat
     3721 ggacaaaggg gtgtaaaaaa cgtggaagct caagaaatca tccgctacat tcaaacggca
     3781 tctaaaaaga cgcctgtgaa agtctatctg aatgtaaccg agccaatcga atttaaagaa
     3841 agtaaagttt ttggtgaagg aagcagcttc gttgtttttg gtgactatga gacgattgct
     3901 ccggttttag aagctgaatc agaaaaaatc attgaaatcg aaatcgaaac tgctgcaaga
     3961 tacagcgcag ttcctttgct agatattaaa aaaattaatg ctcgtatcga accaggtgct
     4021 attatcagag atcaagtgtc aatcggcaac aatgccgtga tcatgatggg agcgattatc
     4081 aatattggtg cagtaatcgg tgaaaacacg atgattgata tgggtgctgt cttaggtgga
     4141 cgagcgacag tgggcaaaaa ctgccatatt ggtgcaggag ctgtcttagc aggtgtgatc
     4201 gaaccagcat cggccaaacc ggttatcgta gaagacggcg tactggtagg tgcgaatgca
     4261 gtgattgttg aaggtgtcca tatcggaaaa gatgcagtcg tggcagcagg agcagtggtt
     4321 ttagaagatg tggcagcaga aactgttgtc ggtggaatac ctgcacgtgt attaaaaata
     4381 agtgatgatc agacaaaaga aaatacagca ttgattgctg cgttacgcga attatagagg
     4441 agatggagaa aaatgcgcga aatagatacc tgtattgtgg gggcaaccgg attagtcggc
     4501 caaacgatgc tcaaagtgtt agaagaatat gattttccag taggacgatt gaaattatta
     4561 gcttcaaaac gttcagccgg taaagtttgt gtattcaaga aaaagaaaca cactgtacag
     4621 gaattgacag aaacttcatt tgaaggatat gatttagcgc tattttctgc aggtgcttct
     4681 gtatccaaag agtttgcgcc aatcgcacga agtcagggac tatttgtcat agataattcc
     4741 tcagcatggc gggaagattc ggatattcca ttaatcgttc cagaggtcaa tctggaagac
     4801 tatacattga atcggctgat tgcaaatcca aattgttcaa ccattcaagc ggtacttccg
     4861 cttaaagctt tacaagaagc ctttggtatc cagcgagtca attattcgac ctatcaagca
     4921 gtttctggtt ccgggcaaaa aggcattgaa gatcttcatc gtacgcaaaa tgacgaggaa
     4981 ccagttttgt atccttataa tattagccaa acggtgattc cggaaatcga tcagcctttg
     5041 gaaaatgggt atacaaaaga agaacagaaa atgataaatg agacccgtaa gattctgcat
     5101 cagcctgctt tgccagtatc agcaacctgc gtacgtgtgc caatcgaaaa tggacatgga
     5161 gtctctgtgg cagttcaact gcaaaaagag tttacgacgg aagaaattag agagtgtctc
     5221 agccagtttc cagggattca attagaagat gatctagcag cacataaata tccgacgagc
     5281 attcttgcta gaggaacaga tatggtttat gttgggagga tcagaaaaga cacttcttta
     5341 gagaacggat tgttgttcta tacgactgcc gataacatac gcaaaggagc cgctgcgaat
     5401 gccgtacaga ttgctgcagc tttaatgcag aaaatagcgg aggtggcaag atgagtaata
     5461 cgctgaaagt agcgaaattc ggcggaacat cgatgtctca tgaagagcaa ttcaaaaaag
     5521 tccgtacaat tgttctttca gatcccaatc gccaagtgat cgttgtttct gctttaggca
     5581 aacgtacgtc agatgatgac aaagtaacag acttacttta tttgatttat gcttaccttc
     5641 agcatcatgt tgattggaca cccctttgga aaaggatttg tgatcgtttc attcaagtaa
     5701 gagatgttct tgccctgcag ttacctattg aagatgaact agcacgcata cagaaacaac
     5761 tggaagacga aaagataact gaagattatt tagtaagtag aggtgaatat ctgactgctc
     5821 aactgatggc tgagtatctt ggttaccagt ttattgacgc aaaagacctg attttctttg
     5881 actatgatgg gaaaatcgat caggaaaaaa cagcacagga aatcacaaaa gcatttaaaa
     5941 gatatccgaa aatggttgtt ccagggtttt acggggcgaa ccctgcagga aaagaaaaat
     6001 tattgggccg tgggggaagc gacattaccg gcgcgatact ggcgaagatg ttgcaagcgg
     6061 aaagttatga gaattggacg gatgtttcag gaatcatgat ggctgatccg cgaatcatcg
     6121 atcatcctaa aatcatcgag gaaatctctt ttagagaact gagagagatg gcttatatgg
     6181 gggctaacgt tcttcatgaa gcagctgttt tcccagttca agaggctgat atccccatcc
     6241 aaataaaaaa taccaatgat cctttcgctc aagggacaaa aatatcgaat cacgaaatag
     6301 aaaaggaaaa tggactgaca ggaatagctg gacgcaagga ttttctttcc atcactttat
     6361 tcaaacgtca tatgtccgat gaaatcgggt ttatctggaa agcaatgagc atttttgcta
     6421 aacatgagat atcaatcgaa catattcctt cagggatcga caatatcgga gtgatcgtct
     6481 cagcagaagc gattgccgat aagttatttc tcatcacgaa agaattaaaa gaaacacttg
     6541 gcgtggaaga aatcgtcgtg atcgaagact tagctttgat ctctgtcgtt gggggtccgc
     6601 ataaagaatt gattggatta tctgggaaag tgttatcgat attgaacaaa ttagaaattc
     6661 gcacatcgat cttatcacaa ggagcacagg agttgaatct gatcatcggt gtaccgaata
     6721 atcaatatga aacagtagtg aagggtatct atgaagggat ggtgaatacg gatgctgaaa
     6781 gaatatcgaa tggcactcca tcaaattcct gaaatcgggt ttcatgaatt caagacaaaa
     6841 aaatatttat atgaacaagt aaaaaacagc gaggccgtta tccatgaaat cggcgaaaca
     6901 ggactactcc tttattttga taatcagcaa gaagaaacga ttgcttttcg aacagatatc
     6961 gatgcactgc cagtcaaaga agaaacgaat ctctcttttg cttctaagca tgaaggttat
     7021 atgcatgcat gtggtcatga cggacatatg gcgatgcttt tagggttgac tgactttata
     7081 actaaacaca ttgaggatct tatttataat gtagtactga tctatcagcc atcagaagaa
     7141 atttccggtg gcgcacaaag cgttattcag tcaggattgt tggataaata tgaagtacaa
     7201 gcaatatttg gctttcatct atggcctgga ctagctaagg gagaagtttt ctctcgacca
     7261 ggacctttga tggcacaaag cagtgaaaca gacattatca ttaaaggcca gtctgcacat
     7321 attgcttcta gtgaaaaagg aatcgatagt ctggaggcag ctgtacgatt tttgaagaat
     7381 gtttatgatt ttgaccggca attaccggca gagtggaatc atctaatgaa atttggccaa
     7441 atccaaggtg gaacgatccg aaatgtttta gctggagaag ttattgtatc cggaagtatc
     7501 cgttcttaca gttcagatat gcaaaattat ttgaagaggg gattagacca tttagcagaa
     7561 cagtttcact ctacagctac tatttctttt cgctataatg acggctatcc agctgtaatc
     7621 aaccatagag gcttatatgc agcactgtta gattcaaaca aactacatga attagatgct
     7681 ccagttcttc aagccgaaga ttttggcata tatacgcaac aatatccatg tgtatttttc
     7741 tttttaggtg tcggtgatac ccctgcttta catgatccga cgttcgattt tgatatggat
     7801 gttttagaaa atggtgtaga atggtacaaa acgattcttt ttacagaaaa tcttcttgta
     7861 aaaatcgata gcagttcaaa agaggagcga gtaaataatg atgaatttat ccaatcgatt
     7921 tagtcctagg ctttctagaa tagaagtatc aaaaatacga caattcgatc agcaaatatc
     7981 gtcgatacca gatgtgatca aactcaccct gggagaaccg gattttccaa ctcctgaaca
     8041 tgtcaagcaa gcaggaatag cagcgattga agaagacttt tctcactata ccggaatgag
     8101 aggattagag gaactgcggg aagcggcttg tatatttcag caacagcgtt atggattaac
     8161 ttatgatccg caaacggaag ttttgacgac agttggtgca acggaagcga ttgcctctgc
     8221 gttgttatct gttttggaag aaggagacaa ggttcttatt ccagcgcctg cttattcagg
     8281 atatcagcca ttagtggaac tagctggtgc tgaattgatc ccgatagata cttctgacac
     8341 agggtttgtc tgtcagccgg aacaatttga acgagcattt gaacaatatg gatcagctgt
     8401 caaagcagtc attttaaact atcctaacaa tcctactggg acgacattgt ctgcaaaaca
     8461 attgaaagca atcgctgagg ttttaaaaaa atatccggta tttgttataa gtgatgaagt
     8521 atatgctgaa ttgacttata gtggaacgca tatgtccata gctacttatc ttccagaaca
     8581 aacaatcgtg ataagcgggt tatccaagtc acatgcgatg actggttggc gagtgggctt
     8641 tatttttgct caaaaagccc ttattgacga actaattaaa gtccatcaat atctggtgac
     8701 tgccgctaca acgatgtcgc aaaaagctgc ggctgaagcg ctaataaatg gggtgaaaga
     8761 tagcgagaat atgaaagagc aatatcaaac acgaagagac tatctggtcc agcaattggc
     8821 gcctttagga tttgaagtga cccagccaaa cggtgcattt tacttgtttt gcaaactccc
     8881 agctgccatt caaactgact cttggcagtt ttgtgtagaa ttagcggaac aggcaaaagt
     8941 tgcgtgtatc ccaggaattg catttggccc agaaggagaa ggttatatcc ggatttctta
     9001 tgctagcagc atggaaaaat tacatgaggc ctgcaaacgg atcaaagact ttttaacaga
     9061 acagtgattc atagatttta tcaaaaaaac aatcgttaat tttgcggtat attctgcaag
     9121 gagacgattg ttttttaaat ttagttcaaa tgaacgcgtt tcttttgatt cataactaat
     9181 gtaatgttaa gtttaaattg tttagaatga ttttaaaaga atattcaagg aggtttcatc
     9241 aatggaaaaa atcaaagttg tcattgtagg tgcatctcat ggagggcatc aatcgatctt
     9301 ggaactattg acacgatacg gtgaaaatgt agatatcacg ctatttgaag caggagacta
     9361 tatttccttc atgtcatgtg gtatggagct gtatttagaa gacaaggtaa cagatgtaaa
     9421 tgatgtacgt aatttcagac cagaaaactt tccgcaatcc aatgttcata ttttaaataa
     9481 tcacgaagta aaaacgatcg atgccgataa aaaaacagta acggttacta gcgcatcaga
     9541 taacgaaaca aaagaatatc cttatgacaa attgattttg agttctggtg tcaaaccaaa
     9601 caatctgcca gtaccaggag cagatctaga aaatgtctac ttgatgcgtg gatacaattg
     9661 ggcaaccaaa atcaaagaaa aattaaatga tccggctatt aaaaaaatcg ctgtcgtagg
     9721 tgcgggttac attgggatcg aagcagcaga agcaagccga aaagctggga aagaagtcgt
     9781 attgcttgat gtgatcgata gacctttagg cacttattta gatgctgaga tgacagatat
     9841 tttagaacaa cacctaaatg aaaacggtat tgaagttttg acaaatgcaa aaatcgaagc
     9901 ttttactggt aacggaaaag ttgaggcaat caaaacaagt gaaaaagaaa tcccagcaga
     9961 tctagtcatt caagctgccg gtgtgaaggc aaatacagaa tggttaaaag ggatcgtcga
    10021 cttagatgaa cgtggctgga tccaaacaaa tgaatacttg caaacgaatc ttccagatgt
    10081 gtatgcagta ggagatgcta cacttgctta ttctatccca gcacgcaaaa aaatgccgat
    10141 cgctttagcg actgttgcac gtagagaagc acgttatgta gtaaaacatc tttttgaaga
    10201 agtaccaaac aaaccgttcg gcggagtcgt aggttcctct gcattaagtg tctttgacta
    10261 tcattttgca gcaagcggat tgaatagctt tacagcagca aaagcaggag tagatgtacg
    10321 agtgtcttat tatgaagata cgttacgacc aaaatatgta ccagaagaac aaggaaatcc
    10381 aaaagtgtcc atccaattat tctcggatcc aatgacccat caattgctag gaggagcagt
    10441 attatctacc tatgatgtta caggtcaagg aaatgtattg gcactagcga tccaaaacaa
    10501 actgacttta gaagaactag cagaagctga cttcttcttc cagccaggct ttgaccgaca
    10561 atggagcatg ttgaatctag ccgctcaaca agcgttagga gaagaaccat ttgtagaata
    10621 agaaaacgaa atatttgaaa agaggttgtg aaaaagctgc cttgcatcaa gtaataagaa
    10681 cagccaagta aaaacagctt cttatgtttt taacttggct ggacttatta ccgcagatgc
    10741 aagcttttga acaccgttta ttttcaaaaa agggactgtg acacgatttg tgtaccgacc
    10801 cccaaaagtt agaccaaaaa atctaacttt tggaggtcgg tattttttat ggttaaatat
    10861 acttttgaac ttaaattaaa gatcgttcat gattatttgg atggcaaag
//
LOCUS       DAFLWQ010000091        10805 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.094, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000091 DAFLWQ010000000
VERSION     DAFLWQ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10805
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.094"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            192..1007
                     /gene="thiD"
                     /locus_tag="L1V16_002431"
     CDS             192..1007
                     /gene="thiD"
                     /locus_tag="L1V16_002431"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBN1276725.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(1336..2787)
                     /gene="cls"
                     /locus_tag="L1V16_002432"
     CDS             complement(1336..2787)
                     /gene="cls"
                     /locus_tag="L1V16_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBN1276726.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            3128..5794
                     /locus_tag="L1V16_002433"
     CDS             3128..5794
                     /locus_tag="L1V16_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBN1276727.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            6158..6910
                     /locus_tag="L1V16_002434"
     CDS             6158..6910
                     /locus_tag="L1V16_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1276728.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(6932..8086)
                     /locus_tag="L1V16_002435"
     CDS             complement(6932..8086)
                     /locus_tag="L1V16_002435"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HBN1276729.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            8271..10712
                     /locus_tag="L1V16_002436"
     CDS             8271..10712
                     /locus_tag="L1V16_002436"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HBN1276730.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
BASE COUNT         3520 a         1921 c         2316 g         3048 t
ORIGIN      
        1 tttattatta gaatagcgaa tacaaataaa cgaccactat tttctgattt attgcaaatg
       61 ttttttcaaa taaatttgat taccaagaaa aggtagtggt atatttactg agggatactt
      121 tgaaaaacat atgatagaaa cagtaacagt attatgaaaa atctttttat aaaaatggag
      181 gaatcgattt gatggaagat cagtatgtac aagcaatgac gatcgcagga tcagatagcg
      241 atggaagcgc agggatgcaa gcagatatgc atacattctt tacaagaaat gtttacggtg
      301 tttctgtcat gaccgcatgt gttgcaggta attcttacgg aatcggagca agtgtgacat
      361 tgccaacaga ttttatcgac aaagaatttg aactgattgc gaaggacttt caaatacgtg
      421 cagctaaaac aggtatgcta gcagattcaa agttgattga gacagttgta aaaaattacc
      481 aaaaatatga ttttggacca ttagtcgtgg atcccgtaat cgtaacgaaa catggaaatc
      541 ttttactaga agaatctgct ttgcaaagct tgaaagaaaa gcttgtccct ttggccgaag
      601 tactgacacc taatttttat gaagcagaaa agctgactgg acggacatta gcagctgaag
      661 aagattttgt gcaagcagca aaagaactgc aagatatggg tgcaaaaaac gttatgatca
      721 aaggacatca tgctaaaaat gcgcagcaag aaacagtcaa tgactacgta ttgttcgaat
      781 caggaaaatc attttggtta aatgcaccat tttatcctac cgaccggatc aacggaactg
      841 gcgattcgct atctgcatgt attgcagctg agttagcgaa aggaaaaaca gttgaacaag
      901 cgatccgatt ggcaaaagac tatgtaaacc gtgcaattcg tgaagaaata aatgtagggc
      961 acaaatatgg ccccatcaat cattgggcag ctggtgaatt agagtaaaag aaagaagttg
     1021 tgaaaaagtt gccctgcatc aagtaataag aacagccaag taaaaacagc ttcttatgtt
     1081 tttaacttgg ttggacttat taccgcagat gcaagctttt gaacaccgtt taagaaagag
     1141 gtcgtgagcc tgccgtccag ctccgagtca caaggaacaa gttcaaaaaa cagcttctca
     1201 tgtttgttga atattgtgac ttgtgaccga ggagttggca ggagaacacc gtttgttcgg
     1261 aagaagggac tgtgacaaga tttttgtcac agtcccttta atcttagtat atttttctct
     1321 acttgaataa aaaaattata ggattggaga aaataatcga gaaatttgtt gcttgaataa
     1381 tagccagtta gacatttcct tgactgtttc agttgtcatg gatgaacaat gtgtctcatc
     1441 ttctttgaac tgagtagcaa gttcttctaa aaactcagga tcgtaaatga cagcacttgt
     1501 ttcaaaattc aatcggtagc tacgaatatc ttgatttgct gaacctacca tgcagatttc
     1561 atcatccatt atcaatgttt ttgcatggag gaagccgttc tcatagacaa ggatttgtac
     1621 attttccttg atcagctgcc gagcataata ttgtgttgct cgataaataa aaggatgatc
     1681 cggtttgttg ggaatcatga ttttcacatc tacaccagag gcagttgcga tttttaaagc
     1741 agcaatgaca ctttcatcag gaacaaggta aggtgtctgt atccaaacac gttttttagc
     1801 agaagtaatc aatttgataa atgaaagctt gatttgttcc ctttcgttat tcggtccgct
     1861 tgaaacaagc tggatggatg tatcagcaag cttagattca tctcgatctg cttttttaaa
     1921 gaaataattc aaatgatagc cgaccttttt ttcttcaggt accgagacgt tccagtctgt
     1981 taagaagcga agctggagca aagaagaagc ggcaccgaaa atccgtatat gcgtatcgcg
     2041 ccaatagccg aatttttttg ttgtatttac atattgattg gcaatattga aaccaccggt
     2101 ataactaatc tttccatcga tcacaacgat ttttcggtga tcatggtaat tcaatcggaa
     2161 acgaagtaat gccctttgtg aggtaacaaa tgtatggaca tgtccaccat ttttgattag
     2221 acgattgaaa tcttttgctt ttgtgccatg agagccaaat gcatcatata atattcgaac
     2281 ttccacgcct tctgcggctt tttcttctaa aacatgtaag acttgctggc cgatattatc
     2341 tgtcacaaat gcgtaatatt cgatatggat cgaatgtttg gcttttttta gatcttgaag
     2401 cagtgaatcc aatttctctt gtccgtctgt gagaagagtg acagaattca ttcttgtcag
     2461 cggcatacga tttaatgaag agaagaagtc aacaaattgc tgtttgtctt tatcgcccat
     2521 gtcaggatcg taatgttcaa tggtatctcc tctaaaagac tgaaagtttt ctaattcttt
     2581 caagtcactt tgtcggagat agaatttttt cttatccgtt aatccacgtc cgaaaaataa
     2641 atataataca aagcccaccc caggaagggc aaacaatact aagagccatg cccaaatggc
     2701 tgctacatct cggggtttga tcaaaatagc caccaaagca ataagtgcat ttaatagata
     2761 aagggcggtt ataatactag ataccacaaa aatgttcctc cttacataca ataacattag
     2821 tatagcatga tagaagaaag aagcctacca aggtgaatat acttttcact cctttcatga
     2881 aaatgtaggt aaatcgggct aaagtagttg ctttttgtag gttaataagg taggatatta
     2941 gtacagttga atatctcctt aggggagtaa ccggcaacgt ttgttgcgat aatatcaaca
     3001 gtaagttaac caaatggttt tctggtattg tatgaaatgg tgagacctaa gacaaatgcg
     3061 tatttgtctt aggtctcttt tttttcagac aggactaggg ccaagatcaa aaaatggggg
     3121 atgaaatttg gaaaacaagg aacaagcaca acaagcggtc tataaagaaa cgatcgactc
     3181 gttgatgcag caaacgcaga gctcaaccga tggattgagc accacgcaag cgaaggaaaa
     3241 attagaaaga gatggcttga accagctaaa agaaaagccg aagaagccaa cttggaaatt
     3301 gttcttagaa actttcaaag atgcaatggt tatcgtattg ctgattgtcg cactgattca
     3361 gatggtcatg ggtgactaca tcgaattctt agttattttt gcagtattga tgttgaattc
     3421 tataatcagt gttgtccaaa caaaaaaagc agaaggttct ttagaagcgt tgaaaaacct
     3481 ttcagcgccc gatgctcgag tgattcgtga tggtaaggaa aaaacgattc cggcaaacga
     3541 acttgtggta ggagatatcg tgttgttaga cgcaggcgat tatgtacctg ctgatggacg
     3601 tttactagat gcgggatcat taaaagtaga tgaaggtatg ctgacaggag agtcgacttc
     3661 tgcagaaaaa gaagtaacgg atatcacaag tacggtacca atcggagatc gtacaaatat
     3721 ggtattcagt ggaacgatcg taacttacgg acgcggtaaa ttcttagtga cttcaactgg
     3781 gaataatacg gagatcggac aagttgctgg ccttttggaa tcaacaactg agcaagtcac
     3841 tccgttacaa cgaggtctgg ataaattcag taaaaaacta agtttggcta ttttggcatt
     3901 gtctttattg attttaggta tccaactgtt tcgtatttat cttggagaag gtacaggaga
     3961 tatgactgca gatatcgtca gcgcagtgat gtttgccgta gccgtagccg tagctgctat
     4021 tccagaagca ttacagtcta tcgtaacaat cgtgttatct ttgggaacga ataaaatggc
     4081 aaaacgtcat gccattattc ggaagcttcc agcagttgaa acacttggtt cgacaagtat
     4141 catctgtaca gataagactg gtacattgac acaaaacaaa atgacagttg ttgactactt
     4201 tttaggtaat ggcgatactg gggatttcac aaatgaccct tcaaaatgga cagctgacga
     4261 acgtcgcttg atcgaaatca gtgttttagc gaatgatgca tcgatcagtg aagacggtac
     4321 taaattgggc gaccctacgg aagtagcgtt tatcgacttt agtgaaaaat taaaccagcc
     4381 ttatcaggaa atccgaaaca actacccaag acaagcagaa cttccttttg actcagatcg
     4441 aaaattaatg tctactggac acacaattga taacaaaaat tacttgtttg ttaaaggcgg
     4501 accagatatc gtcttccaac gcagtaaaaa agtattgcta aatggtgaag tcgttccgat
     4561 gacggatgaa ttgatgaaaa aattccaaga gcaaaatgaa gctttttcaa cacgcgcatt
     4621 acgtgtacta gcttttgctt accgtccact tgataatttt gatttatcat ttgaagatga
     4681 agacgatttg atccttgttg gtttgcttgc tatgatcgat cctccacgtg ctgaagtgac
     4741 tcaggcggta acagaagcaa gaagtgcagg aatcaaaaca atcatgatta ctggtgacca
     4801 caaaacaaca gctgttgcta tcgcaaaaca aatcgggatt tttgaagaag gaaacctggc
     4861 tttgaccggg acggaactag atgaattgac agaagatcaa ctaaacgaag ttttagaaaa
     4921 agtcactgtt tatgcacgtg tttcacctga gaataaaatt cgtatcgttc gtgcttggca
     4981 aaataaaggt catatctcag ctatgacagg tgatggtgta aatgacgcac cagcattgaa
     5041 acaagcagac atcggaattg ctatgggaac gggtacagat gtggcaaaag atgcagcagc
     5101 gatggtattg acggatgata actttgcttc tattgtcagc gcagtagaag taggacgtaa
     5161 tgtgtttgat aatatcaaga aagctatttc ttatctattt gcaggaaatt taggtgcgat
     5221 cattgcgatc atctttgcct tagttgctga ctggtccaat ccatttacag cattacaact
     5281 gttgttcatc aatttagtca atgattcact gccagcaatt gcattaggta cagaaaaagc
     5341 tgaacctgct acgatgaacc gcccgccaag agatccaaat tcaggaatct ttacggacaa
     5401 aacattgatt tctgtaacgt atcgtggtgt gctgattggg attgctgtta tctttgctca
     5461 atggcttggc atgcagcatt cacctgaatt cggtgtagcc atgtcatttt caacattgat
     5521 ttggtgtcgg acattgcaaa cattcccagc acgttcaaac acacaaacag ctatccaagc
     5581 agggttcttc tctaacagaa gtgtcttact agctgtagtt gtatgtagcg cgctttactg
     5641 cttaacaatg atcccaggac tgaaagaagt cttctctatc ccatcagcat ttggattgac
     5701 agaagtcttt acatgtatgg gaatcgcact tgtgacaatt gttttgatgg aaatcactaa
     5761 attgatcatt gtacgagtac aaggaaataa ataaaacgaa tcaacgaggt tgtgagcctg
     5821 ccgtttaatt ctgagtcaca aggtgcaatt tcaacaaaca gcttctcatg tttgttgaat
     5881 attgtgactt gtgaccgaag agttggcagg agaacaccgt ttaaggaaga agttgtaaaa
     5941 tcagcatttt gagctaatac tgagggtcat ctgattggac actgtttatt cggaaagagg
     6001 gactttgaca cgactttggt cacagtccct ttttttattt atgatagacg gaaagccaat
     6061 cattttatta ttcatcaaaa gagatagaat agataaaaga ggagaatgat ttattccgaa
     6121 aagtgaaaac atataacaaa aaattagagg aaatcaaatg aatgaaaaag aatgggatga
     6181 atttgctgaa gaatattatg aaatccagca agaatcgcaa gtaactattg ctgaagatgt
     6241 aaaaaattat ctgaaaacgg agaaagtcct gcctgctgaa acagcagcag acgttgctgg
     6301 aggatctggc agatttcttt ccttagcaaa agaaattaat cgctatgatt tgatcgattt
     6361 ttcttcagga atgctagaaa atgcaaaaaa agaagcagaa aaaaatgagt tgccaaatgt
     6421 ttcctttatc aaacagtcgt tagaagaatt tatccaatca aatgagacat atgaaatggt
     6481 ttttacagca gcaaatccag cattggtaca tcttattcaa ttagaaaaat tgatgaaaaa
     6541 gtcaagcaaa tggtgcgtga taatcagagt agtggaatca atcgatgatg ttttttatcc
     6601 tatcgaaaag caactaggaa tgatagaaga agatcctaat acatcgccag ttgtaatgga
     6661 tcaatttgaa acatacttaa ttgatgaagg attcaaagtg aagaaaaaag attttactta
     6721 ttttacacag gaatcaatta ctgaagaatt gatgaagcta tactatgacg cgtacgcaaa
     6781 agatcctgtt gtgaccaggt acattcgcaa actattcagt gaaaaacgag aaatccttag
     6841 tacgactaag ctgacctata gactgctcct ttggtccgca gataaaaaaa gaacctttca
     6901 cgactcgtga agggttcttt ttatgatttt attatatttt gtagtaacga atatcatttt
     6961 cgatctttgt aatcgaaaaa ggtacatctg aagtatattc tgcacattct ccgtgttcag
     7021 gaagcgtctc actgaaaatc gtttcatatt cgtcaacagt gatccgtgtt cgagaatcta
     7081 gcatctcttg atgagattgt gcgaagagat attcttgata gttttcttcc agataacctg
     7141 taaaaaattc acttactgca ccagaaccgt agctgaatag accgatgcga tctcctggct
     7201 gtagtgattt cgaattttcc agtagagaag ttagccccag gtataatgaa ccagtgtaaa
     7261 gattaccgat tcgtcggctg taacggatgc tttcttcata gcgagccata agacgttcct
     7321 gattttcttc gtctgtttgg tctaatacgc tttgcaatgc cttttttccc atcttagtat
     7381 acggaatatg gaaagcaatc gcctgataat cttcgagtcc tcgacccgac aattctttat
     7441 gtcgattcca aactttttgg aatgattcga tatacgtaga attagataaa ggaccatcaa
     7501 caacaggaaa ttcgctataa tctggacgcc agaaatcata gatatcttct gtcagaaata
     7561 cgctgtcgtc ttcaatcgat aaaatacgcg ggttttgagt gatcatcatc gcaacagcac
     7621 cgacaccttg cgtcacttca ccaccgcttg ccaagctgta acgagcaata tcacttgcta
     7681 tgactagtac ttttcgttct ggatgatttt tgacatattc tttcgccatg tgcaaagctg
     7741 cggtgccacc gtagcaagcc tcttttactt caaaagaacg agcaaaagat tggattttca
     7801 gtaaatggtg gataattacc gcactcgctt ttgaatgatc aatcccggat tctgttccga
     7861 cgatgaccat gtcgattagc tcacggtctt tttctgttac gattttgctg gcagcatttg
     7921 ctcctagtgt aatgatgtct tcatttgcac gattgactgc catttggtct tgaccaatcc
     7981 ctatatggta ttttgcagga tcatccccac ggctttctgc caactctgtc atatctaaat
     8041 ataaattagg aataaaaaag gaaagacgat caatccctat tttcatttca acacctcttt
     8101 acttatgata aaaaacttac tttactaagg tatcataaaa agattaaaag aaatataaaa
     8161 aagagaatat ttaaggattg ttaaaattta atcttagaaa aaaataactg gaacaagagc
     8221 tatttgtttt tacagcaaag aatggtatat ttttgtagga ggtggcttac ttgaaagaag
     8281 tcgttatgat agatgctgca agaacgccga taggaaagta tcgcggaagt ttaagtccat
     8341 ttactgcagt tgaattaggc acacttgtga ctaaaggatt attagataaa acaaaactga
     8401 aaaaagataa aatcgatcaa gtaatatttg gaaatgtcct gcaagctggt aatggtcaaa
     8461 atgttgccag acagattgct ttgaacagcg gtctccctgt agatgtccca gcaatgacga
     8521 tcaatgaagt ttgcggatct ggtatgaaag cagtgatctt agcacgccag ctgatccaat
     8581 taggtgaagc agaacttgtg atagccggcg gaacagagag tatgtctcaa gcacctatgc
     8641 tgaaacagta tcagtcagaa acaaatgaat atggtgaacc aatttccagt atggtcaacg
     8701 acggattgac tgacgcattt tcaaatgcac atatgggatt aaccgcagag aatgttgcaa
     8761 cacaattttc tgtgagcaga gaagagcagg atcgctatgc cttgtcgtcc cagttgaaag
     8821 cagcacatgc tgtcgaagcc ggtgtatttt ctgaggagat catcccagtc aagatttctg
     8881 atgaagacgt gttatctgag gatgaagcag ttcgtggaaa tagtacattg gaaaaactgg
     8941 gcacgttacg tacagtattc tcagaagaag gaactgtaac agcaggaaat gcttccccgt
     9001 tgaatgacgg tgcctctgtg gtgatccttg catccaaaga atacgcagaa aataataatc
     9061 tgccttattt agcaaccatc aaagaagtag cggaggtcgg tattgaccca agtatcatgg
     9121 gaatcgctcc aatcaaagcc attcaaaaat tgacagatag atcaggaatg aatttatcaa
     9181 caatcgatct ttttgagatc aatgaagcat ttgcagcttc ttctatcgta gttagccaag
     9241 aactgcagtt agatgaagaa aaggtcaata tatatggagg agcaatcgca ttaggccatc
     9301 caattggtgc aagcggtgca cgtatcttga ctacattagc ttacggattg cttcgtgaac
     9361 agaagagata cggtattgct tcattatgta ttggtggagg tttaggcttg gcagtcttgt
     9421 tagaagcgaa tatggagcaa acacataagg atgtgcaaaa aaaaaagttt tatcagctta
     9481 cgccatctga acggcgcagt caattaatag aaaaaaatgt attgacacaa gaaactgcgt
     9541 tgatttttca ggaacaaaca ctttctgaag agctctccga tcacatgatc gaaaaccaag
     9601 tgagtgaagt ggaaatccca atggggatcg cgcagaattt tcaaatcaat ggcaagaaaa
     9661 aatggattcc gatggcaaca gaggaaccat ctgtcattgc agctgcaagt aatggtgcaa
     9721 aaatctgtgg aaatatctgc gcagaaacac ctcagcggct gatgcgaggg caaatcgttc
     9781 tatcaggaaa atcggagtat caagcagtga tcaatgcagt taatcatcga aaagaagagc
     9841 tgattctttg tgcaaatgaa agttatcctt caatcgtgaa acgcgggggc ggtgttcaag
     9901 atatctctac tcgggaattc atggggagtt tccatgcata cttatctatt gattttttag
     9961 tggatgtaaa agatgcaatg ggcgctaaca tgatcaactc gattcttgag agtgtggcaa
    10021 acaagttacg ggagtggttc cctgaagaag agattctatt cagtatttta agtaattttg
    10081 ctacagaatc attggcttct gcctgttgtg aaatcccatt cgaacgctta gggagaaaca
    10141 aagaaatcgg tgaacaaatt gccaaaaaaa tccaacaggc aggggaatat gcgaagcttg
    10201 acccttaccg tgcagcaacg cacaacaaag ggatcatgaa tggtatagaa gctgtagtgg
    10261 cagctacagg aaatgataca cgtgcggtta gcgcttcgat ccacgcctac gcggcaagaa
    10321 atggattata ccaaggatta acagactggc agatcaaagg ggataaacta gttggaaaac
    10381 taacggtgcc tttggctgtt gccacagtag gcggagcttc caatatcctg ccaaaagcaa
    10441 aagcatcttt agctatgtta gatattgatt cagccaagga actagcacaa gtaattgctg
    10501 cagtagggtt agctcaaaac ctggctgctt tgcgtgcatt agttacagaa ggaatccaaa
    10561 aaggccacat gggacttcaa gctcgttcat tagcgatctc aattggggct attggtgagg
    10621 aaatcgagca agttgcgaaa aaattacgtg aagcagaaaa gatgaaccag cagacagcta
    10681 tacaaatatt ggaaaaaatc cgggaaaaat aaaaaagcaa tatctttaga agaataaagc
    10741 aagatttaca gttattttat ttactgcaga tcttgctttt ttggctcttc gtcaaattgt
    10801 gttgg
//
LOCUS       DAFLWQ010000092        10742 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.095, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000092 DAFLWQ010000000
VERSION     DAFLWQ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10742
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.095"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..370
                     /locus_tag="L1V16_002437"
     CDS             <1..370
                     /locus_tag="L1V16_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBN1276731.1"
                     /translation="PVIVHPERNAHFREDPNHLLPFLDMGCLAQLTAPSYVGVFGKDI
                     QKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFGKEKVVQMKQVAKDLIN
                     GDEISYPIYEEVKKKKFGLF"
     gene            383..2200
                     /locus_tag="L1V16_002438"
     CDS             383..2200
                     /locus_tag="L1V16_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1276732.1"
                     /translation="MFVLTRRRKIATLVFVDSLLLIAANIAAAKFMKPFVAIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAVFGSLSASAVSSIIILLFINRRYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYVETKNMRYLSTDSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESARVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAARVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAQGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNK"
     gene            2211..2843
                     /locus_tag="L1V16_002439"
     CDS             2211..2843
                     /locus_tag="L1V16_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBN1276733.1"
                     /translation="MKAIIVGAGGFGKEIAFLLQSVSRYELVGFVDDSLKMQNQELLE
                     KPILGTIDLLIELEEETAIFLGIASPDIKEKIYQKINKNNKLIFPNLVAPSALVGINV
                     QLGIGNILMPYTTYTADVVLGNFNMINIGSTIGHDTQIGNYNSVFPSVNISGHVILGD
                     KNEIGVGTKIIQNLSIGNTNIIGAGSVVIKNINNNTKNVGVPTKVIERWD"
     gene            2881..3963
                     /locus_tag="L1V16_002440"
     CDS             2881..3963
                     /locus_tag="L1V16_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013554917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBN1276734.1"
                     /translation="MSEEGYEQEYVKEAFDTNWVAPLGANVNGFEKELAEYVGASHAA
                     ALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPILYQGAIPVFVDSDYETWNMK
                     PEHLRTALEKYPNTKAVLVVHLYGLSANLDEITKICKEYDVTLIEDAAESLGTTYKGK
                     YTGTFGDYGIYSFNGNKIITTSGGGMLVSNEKEKVEKVRFWATQSREKARHYQHNEIG
                     YNYRMSNIVAGIGRGQLKVLNERIEKKRYIHNFYKKELSKLSNIQFMPENNWNEPNYW
                     LSVITIKGINTNHLIDELDKNNIEARPVWKPMHLQPVFKNYDYIGDDVAETLFDLGVC
                     LPSDTKMTDEDLKYVVSTIKRVINDA"
     gene            3953..4573
                     /locus_tag="L1V16_002441"
     CDS             3953..4573
                     /locus_tag="L1V16_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBN1276735.1"
                     /translation="MMRKKTFYQLFGKRILDILLSGIALIVLSPIILIVGFLVRIKLG
                     SPIIFKQERPGKSEKIFSMYKFRTMTDERDHNGEYLPDEIRLTKFGKILRATSLDELP
                     ELWNILKGDMSIVGPRPLLVEYLPLYSEKQRKRHNVRPGLTGLAQVNGRNAISWEEKF
                     DLDVYYVDKISFFNDLIIIIQTCKKVIKKENINTINNNIPEKFKGS"
     gene            4581..5795
                     /locus_tag="L1V16_002442"
     CDS             4581..5795
                     /locus_tag="L1V16_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBN1276736.1"
                     /translation="MPLNILFLTLLDFQSLEESNIYTDLMSEFVKNNHNVSIISPTER
                     KKRIKTHLIEINDKCEILKLRIGNIQKTNLIEKGFSTIQIERKFISGINQYFSNKKFD
                     LVIYSTPPVTFAKVVKFIKKRDNCKSYLLLKDIFPQNAVDLNQLSKNTYIYKYFRKKE
                     VSLYEVSDYIGTMSEQNSQYIRKHNKIDEQILEVNPNSIRINENKIGSPLDKEEIRNL
                     YKIPKEKTIMLYGGNLGKPQGIDFLLNIISSLEKDNKILLLIIGSGTEYGRIRKHINT
                     NNIKNTILIDSLSKNEYKKVESIADIGLVFLDKKFTIPNIPSRILGYMESKKPILAAV
                     DKHTDLNEMIKTGKFGYCSEHGDLNAFLSNMERLKDEKIRNELGKNAFIYLKNNFDVK
                     RSYSIIMNHFEL"
     gene            5811..6833
                     /locus_tag="L1V16_002443"
     CDS             5811..6833
                     /locus_tag="L1V16_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1276737.1"
                     /translation="MFKDKILLITGGTGSFGNAVMKRFLDSDIKEIRIFSRDEKKQDD
                     MRKKYNNDKLKFYIGDVRDINSVKNAMYGVDYVFHAAALKQVPSCEFFPMEAVKTNIM
                     GTDNVVTAAIEMGIQKVICLSTDKAAYPINAMGISKAMMEKVFVAKARTVTDERTMIC
                     GTRYGNVMASRGSVIPLFIDQIKNGKPLTVTDPGMTRFLMSLEEAVELVVFAFQNAKA
                     GDIMVQKSPASTVGDLAQAIKELFHADNEIHIIGTRHGEKRYETLLTKEEYLVAQDMG
                     DFYRVPADTRDLNYDKYFVEGSKELTQEGEYNSDNTQRLSVEQIKERLLELDYVRKEL
                     KEWQNQ"
     gene            6830..7939
                     /locus_tag="L1V16_002444"
     CDS             6830..7939
                     /locus_tag="L1V16_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CapF"
                     /protein_id="HBN1276738.1"
                     /translation="MNILVTGSNGFIGKNLVAELKNEGFTDILSFDRDTPVHLLDEYC
                     EKADFVFHLAGVNRPKDDAEFMTGNFGFTSELLEKLKEHGNTCPVMISSSIQAELNNS
                     YGKSKKAGEDLLKKYQKETGAPVYIYRFSNLYGKWSQPNYNTVVATFCYKIARDEEVT
                     VNDPSAIIELCYIDDVVKELLHCLNGQPYTENGYCAVRETDEVTVGELKELITSFKNS
                     RTNLSVPNLARRVEKNLYSTYLSFLPEDEFSYFLKMNVDNRGSFTEFLRTKDRGQVSV
                     NISKPGITKGNHWHHTKNEKFLVVSGEGVIRFRKVDSNEIIEYFVSGEKLEVVDIPVG
                     YTHNIENLGSTDMVTVMWVNEPFDPEHPDTYYVEV"
     gene            7943..9067
                     /gene="wecB"
                     /locus_tag="L1V16_002445"
     CDS             7943..9067
                     /gene="wecB"
                     /locus_tag="L1V16_002445"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HBN1276739.1"
                     /translation="MKKLKVMTVVGTRPEIIRLSAVINRLDRSEAIDHILVHTGQNYD
                     YELNEVFFEDFKLKKPDYFLNAATGTAIETVGNILIKIDPILEEVKPDAFLVLGDTNS
                     CLCAIAAKRRHIPIFHMEAGNRCFDQRVPEETNRKIVDHTADINLTYSDIAREYLLRE
                     GLPADRVIKTGSPMFEVLNSRKDDIQHSDVLNRLGLKEGQYFVVSAHREENISSETNF
                     LHLVDSLNTIAETYQLPIIISTHPRTMKMIEAKEIKFHELIQTMKPMGFNDYNKLQIN
                     AKAVLSDSGTISEESSILNFKALNIRQAHERPEAMEEASVMMVGLEKERIMQGLEVLE
                     TQQKDTLRHVADYSMPNVSEKVLRIILSYTDYVNRVVWGR"
     gene            9064..10119
                     /locus_tag="L1V16_002446"
     CDS             9064..10119
                     /locus_tag="L1V16_002446"
                     /inference="COORDINATES: protein motif:HMM:NF012744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1276740.1"
                     /translation="MRIVVNDIAASEGGAMSVLRDLHSDIISSGDENEWIFLLGEKFI
                     EESDNIKVLTFPKIKTSWIKRLDFDFISGKKIINKLQPDIYLSLQNTATIGVKAPQYV
                     FLHQPLPYQKEKNFSFIKKKEFKMATYQHVIGKIYSILFKKTKATIIVQTQWMKENVS
                     SILNNKILKVDTKINIDENIINKQINENKRNMKHFFYPASNIPYKNHDFLIESFSKCK
                     DKELRLFLTLSRDEIDIKDDRIILLGKVPREKVFDIYSKSNLIFPSSIETLGLPLLEA
                     QCFMSPILALETEFSKEALSGYPHKYLFKLDNLDNLSHLIEKISTSSIVFNVENVIYK
                     KENRVSILDILKGENIY"
     gene            10116..>10742
                     /locus_tag="L1V16_002447"
     CDS             10116..>10742
                     /locus_tag="L1V16_002447"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276741.1"
                     /translation="MKKFVVAHPAQQHSYKIAEALIEKEMLFKYITSVYLKKGSILNK
                     LLNIIPGENKLRAKGRHSDKICDEEVLLINEFSGLLLLILQRVKFLKHLYKKYWDFHN
                     KKFNKKLIKYINSNIDEISGVIVFDQVSFDFFKKKINIPIILDMSAPSVVFMKSQFEK
                     YGISTLKYDALLKKNNFEINSADFFIGASSITERSLLNMGIEKKQIKIF"
BASE COUNT         4014 a         1550 c         2029 g         3149 t
ORIGIN      
        1 accagtgatc gtccatccag aacgtaacgc gcattttcgc gaagacccaa atcatttgct
       61 tccgttccta gatatgggat gtttggccca actcactgcg ccaagttatg ttggggtatt
      121 tggcaaagac atccagaaaa cagccaaaac gatggtcaaa cataatcttg tgcagatggc
      181 tgcttctgat gcccatgggg tctctaagcg caccttttac ttaaaagagt gctatgaaca
      241 gattgccaag gactttggta aggaaaaagt agtacagatg aaacaagtcg caaaggatct
      301 gatcaacggg gatgaaatca gttatccaat ctatgaagag gtaaaaaaga agaagtttgg
      361 tttattttag ggggaatgta gggtgtttgt attaacaaga agaagaaaaa ttgccacatt
      421 ggtatttgtg gacagcttgt tgttgattgc tgcgaatatt gcagcagcta aattcatgaa
      481 gccgtttgta gctataccaa tggaccttat tttaatctct atcggtttgt cgattggttt
      541 ttatttattc tatggtagtt tattcaaagt attcactcgg atcaatcgct atacaaattt
      601 aagagaaatc attgcggttt ttggctcact atctgcaagt gctgtctcaa gtatcatcat
      661 attgctgttc ataaatcggc gatacagttt acgtttagtc atttttgctt acctgctttc
      721 gctattattg attattggta gccgattgat ctggcgtatc tatgtcgaaa caaaaaatat
      781 gagatatcta tccacagatt ctgctaaaaa tacattgatt gtcggtgctg gcgaaggcgg
      841 gcgtatttta tacaacagct ttcttggatc caaaacggct caagatatcc acgttgtcgg
      901 gtttgtagat gatgatccaa ataaaagaaa tacgtatctt tcaggaaaaa aagtattagg
      961 tgcattaaaa gatattccgg aattgattga aaaatatgac attcaaatgg taacgatcgc
     1021 tatcccttcc ttatcaagaa aaaaattacg aagaatcttc gagttagtcg aatccgctcg
     1081 tgtgaaagtc aacacgatgc cttctataga agaacttgct tcaggaaaaa ttagcgtatc
     1141 aaaattaaaa acaattgacg tagtggattt actgggaaga gatgaggtaa agctggatat
     1201 tgaatccatc aaagatcaga tcacagacaa agtcattctt gtcaccggcg caggaggatc
     1261 gatcggttca gaaatctgtc ggcaaatcat tcaattcaat cctgcaaagc tattgctttt
     1321 aggacatggg gagaactcga tctacttgat tgaccgtgag ttacgcacgc atcatcaaaa
     1381 ttgtcctaca gaaatcgtac cgatcatcgc agatatccaa gatcgcgaga aaatcaatga
     1441 gatcatggaa caatatcatc cagatatcgt ctaccatgca gctgctcata aacatgtacc
     1501 actgatggaa tataatccaa aagaagcagt caaaaacaat attttcggta caaaaaatgt
     1561 agcagaagca gccaaagcag caagagtgaa aaacttcgtc atggtatcga cagataaagc
     1621 taacaatcct ccaaacgtca tgggttcaac aaaacgaatc gctgaaatga tcgtgactgg
     1681 attgaatgaa gaaggctgta cgaaattctc agctgtcaga tttgggaatg tccttggttc
     1741 tcgcggtagt gtgattccag tattcagaga acaaattgct caaggtggtc caatcactgt
     1801 aacagacttt cgtatgaccc gatacttcat gacgattcct gaagcgagtc gtttagttat
     1861 tcaatctggc gcattagcaa aaggtggcga aatttttatt ctagatatga gtgaaccagt
     1921 gaagattgta gacctagcca aaaacatgat ccgattgagc gggtatagcg aagacgaaat
     1981 cgaaatcatt gaaacaggta tccgtccagg ggaaaaacta tatgaagaac tattgttgga
     2041 taaggaaaga aatgatgaag cagtttatga gaaaatcttt gtaggaaaca tcaaaggtta
     2101 ctcaatacaa aaagtgatgg attttgtcaa gagcctgccg caagacgatg aacaactggc
     2161 taaagacatt gtcacttttg caaatgcttc aaataagtag ggggagtaaa gtgaaagcaa
     2221 ttattgtagg agctggtgga tttggcaaag agattgcttt tctattacaa agtgtctcta
     2281 gatatgaatt ggttggtttt gtcgatgatt cgttaaaaat gcaaaatcaa gaattattgg
     2341 aaaaacctat attaggaaca atagacttgt taatagaatt agaagaagaa actgctattt
     2401 ttctgggaat tgcttcgcca gatatcaaag agaaaatata tcagaagata aataaaaata
     2461 ataaattgat tttccctaat ttagttgcac caagtgcact agtgggcata aatgttcagt
     2521 taggaattgg caatattttg atgccctata cgacttacac tgctgacgta gttttaggaa
     2581 atttcaatat gatcaatatc ggctctacta tcggacatga tactcaaatc ggtaattata
     2641 attcagtttt tccaagtgta aatatttcag gacatgttat attaggagat aaaaatgaaa
     2701 ttggagtagg tactaaaata atacaaaatc taagtattgg aaatacgaat attataggtg
     2761 caggaagtgt agtaataaaa aatattaata acaatactaa aaatgttggc gtacctacca
     2821 aagtaataga aagatgggat taagttggaa aataaacgaa tattattagc atctcctcat
     2881 atgagtgagg aaggatatga acaagagtat gtaaaagaag catttgatac aaattgggtg
     2941 gctcctttag gtgcgaatgt gaatggattt gagaaagaat tagcagaata cgtgggagct
     3001 agtcatgctg ccgcattatc ttctggaaca gcagctatac atttagcttt gaaagcggct
     3061 ggggtcggta aagatgacat agtgatttgt cagtccttga cgttctcagc tactgctaat
     3121 ccaattctct atcagggagc tatacctgta tttgttgata gtgattacga aacttggaac
     3181 atgaaacctg aacatttgcg aacagcgcta gaaaaatatc ctaacacaaa ggctgtatta
     3241 gtagtacatt tgtacggttt atcagctaac ttagacgaaa ttactaaaat atgcaaagaa
     3301 tatgatgtta ctctaattga agatgctgca gaatcattag gaacaacata taaaggaaaa
     3361 tatactggta cattcggcga ctatggaatt tattctttta atggaaataa gataatcaca
     3421 acttcaggtg gcgggatgct tgtgtctaat gaaaaagaaa aggtggaaaa agtgagattt
     3481 tgggctacac aatctcgtga gaaggcacgc cattatcaac ataatgaaat tggctataat
     3541 tatcgaatga gcaatatcgt tgcaggtatc ggtcgaggac aattgaaagt tttaaatgaa
     3601 agaattgaga aaaaacgata tattcataat ttttataaaa aagaattgtc taaattgtca
     3661 aatatacaat tcatgccaga aaataattgg aatgaaccga actattggtt aagcgtcata
     3721 acaataaagg ggataaatac gaatcatctt attgatgagt tagataaaaa taacatagaa
     3781 gcccgcccag tatggaaacc tatgcattta caacctgttt tcaaaaatta tgattatatt
     3841 ggcgatgatg tagcagaaac tttatttgac ttaggagtat gtttaccatc agatacaaag
     3901 atgacagatg aagatttaaa atatgtagta tctacgatta aaagagtgat caatgatgcg
     3961 taaaaaaact ttctatcagc tttttgggaa aagaatttta gatatcctat tgtcaggcat
     4021 tgctctcatc gttttatcgc cgataatctt aattgtaggt tttttagtaa gaattaaact
     4081 tggttctcca attatcttca aacaagaacg accaggaaaa agtgaaaaaa ttttttccat
     4141 gtataaattt cgtacaatga ctgacgaaag agaccacaat ggagaatatt tacctgatga
     4201 aattcgacta actaaatttg ggaaaatact tagagcaaca agtctagatg agctaccaga
     4261 actttggaat attttgaagg gtgatatgtc gatcgtagga cctcgtccat tattagtaga
     4321 gtatttgcca ctatatagtg agaagcaacg gaaaagacac aacgtaagac caggattaac
     4381 tggactagct caggtcaatg gaagaaatgc gattagttgg gaagaaaagt ttgatttaga
     4441 tgtttattat gttgataaaa ttagtttctt taatgatctt attattataa ttcagacatg
     4501 taaaaaagta atcaagaaag agaatattaa tacaatcaat aacaatatac cagaaaaatt
     4561 taaagggagt taaatatagt atgccattaa atattttatt tcttacgctt ttagattttc
     4621 aaagtttaga agaaagcaat atctatactg atttgatgtc tgaatttgta aaaaataatc
     4681 acaatgtgtc cattatatct ccaacagaaa gaaaaaaaag aataaaaact catttgatcg
     4741 agataaatga taaatgtgaa atcttaaaat taagaatagg aaatattcaa aagactaatt
     4801 taattgaaaa aggtttttct actatacaaa tagagagaaa atttatatca ggcattaatc
     4861 aatatttttc aaacaaaaaa tttgatctgg ttatttattc tactccgcca gtaacttttg
     4921 ctaaagtggt gaagtttata aaaaaaaggg ataattgtaa aagttatctt ttactaaaag
     4981 acatatttcc acaaaatgca gttgatttaa atcaactctc taaaaatact tatatatata
     5041 agtattttag aaaaaaagaa gtttctctat atgaagtatc tgattatata ggaacaatgt
     5101 cagaacaaaa ttctcaatat ataagaaaac ataataaaat tgatgagcaa attttagaag
     5161 taaatcctaa ttcaattaga ataaacgaaa ataaaattgg atcccctcta gacaaagagg
     5221 aaataagaaa tttatataaa attcctaaag aaaaaactat aatgttatat ggaggaaacc
     5281 tagggaaacc tcaaggtatc gactttcttt taaatattat aagtagccta gaaaaagata
     5341 acaaaatttt attgctgatt attgggtcag gaacagaata tgggcgtata agaaaacata
     5401 taaatactaa taatataaaa aatacaattc taattgatag tttatctaaa aacgaatata
     5461 aaaaagttga atccattgcg gacataggat tggtatttct agataaaaaa tttactatcc
     5521 ccaatatacc ttctagaata ttaggatata tggagtcaaa aaaacctatt ttagctgctg
     5581 tagacaagca tactgattta aatgaaatga taaagactgg aaaatttggg tattgttctg
     5641 aacatggaga tttaaacgca tttctaagta atatggagcg attaaaggat gaaaaaataa
     5701 gaaacgaatt aggtaaaaat gcttttattt atttgaaaaa taattttgat gtaaaaagaa
     5761 gctattctat aattatgaat cattttgaat tataaaaagg agcaatttaa atgttcaaag
     5821 ataaaatttt attaatcaca ggcggcacgg gttcttttgg gaacgcagtg atgaaacgct
     5881 ttttagattc agatatcaaa gaaatacgta tcttttctcg tgacgagaaa aaacaagacg
     5941 atatgcggaa aaaatacaat aatgacaaat tgaagtttta cattggagat gttcgggaca
     6001 tcaacagtgt caaaaatgcg atgtacggcg ttgattatgt cttccatgca gcagcactta
     6061 aacaagtacc ttcttgtgag tttttcccta tggaagctgt gaaaacaaat atcatgggaa
     6121 cagataatgt cgtaactgca gcaatcgaaa tggggattca aaaagttatt tgcttgtcca
     6181 ctgataaagc tgcttatcca atcaatgcta tggggatttc taaggctatg atggaaaaag
     6241 tatttgttgc taaagcaaga accgttactg acgaacgcac gatgatttgt ggcacacgtt
     6301 atggaaatgt aatggcttct agaggatcag ttataccatt attcattgac caaataaaaa
     6361 atggtaaacc attaacagtg acagatcctg gcatgacaag atttttgatg agtttggaag
     6421 aagctgtaga gttagttgtt tttgccttcc aaaacgcaaa agcaggggat atcatggttc
     6481 aaaaatcacc agcttctact gttggcgacc tagcgcaagc catcaaagaa ttattccatg
     6541 cagacaatga gattcatatc atcggaacgc gacatggcga aaagcgttat gaaacactac
     6601 tgacaaaaga agaatactta gttgctcaag atatgggtga tttctatcgt gttcctgcag
     6661 atacacgtga tttgaattat gacaagtatt tcgttgaagg aagcaaagag ttgacacaag
     6721 aaggagaata caattcagat aatacacaac gtttatctgt agaacaaatc aaagaaagac
     6781 ttcttgaact ggactatgta agaaaagaat tgaaagagtg gcaaaatcaa tgaatatttt
     6841 agtaactggg tcaaatggtt ttattggaaa aaatttagtt gctgaattaa aaaatgaagg
     6901 attcacagac attcttagtt ttgatagaga cacgcctgta catttattgg atgaatattg
     6961 cgaaaaagca gactttgttt ttcatttagc tggagtgaac agaccaaaag acgatgctga
     7021 attcatgaca ggaaattttg gttttacttc agaattgcta gaaaaactaa aagagcatgg
     7081 caatacatgt cctgttatga tttcctcttc tatccaagca gaacttaata attcttatgg
     7141 caagagcaaa aaagccggag aagatctatt aaagaaatac caaaaagaaa caggagcacc
     7201 tgtatatatt tatcgcttct caaacttata cggtaagtgg tcgcaaccaa attataatac
     7261 agttgtagcc acattttgtt acaaaatcgc aagggacgaa gaagttacgg taaatgatcc
     7321 gtctgctatc atagagcttt gttatatcga tgatgtcgtg aaggaactac tccattgtct
     7381 gaacggacaa ccttatacag aaaatgggta ttgtgctgtt cgtgaaacgg atgaagtaac
     7441 ggtcggcgaa ttaaaagaac taattacatc tttcaaaaat agtcgaacga atttgagtgt
     7501 tcctaatctt gcgagaagag tagaaaaaaa tctgtacagt acgtacttaa gcttcttacc
     7561 agaagacgaa ttttcttatt ttctaaaaat gaacgtagac aatcgaggat cgtttactga
     7621 atttttaaga acaaaagacc gcggtcaagt atctgtcaat atttccaaac cgggaatcac
     7681 taaaggaaac cattggcatc atacaaaaaa tgaaaaattc ttagtagtaa gcggagaagg
     7741 tgtaatccgt tttagaaaag tagactcaaa tgaaataatc gagtattttg tttcaggaga
     7801 aaaattagaa gtagttgata ttccagtagg ttatacgcac aatatcgaga atctgggatc
     7861 aacggatatg gtgacagtga tgtgggtaaa tgagccattt gatccagaac atcctgatac
     7921 ttattatgtg gaggtctaat caatgaaaaa attaaaagtg atgacagtag taggaacccg
     7981 accagaaatc attcgtttgt ctgctgttat caaccgtttg gatcgatcag aagcaatcga
     8041 tcatatttta gtacacactg gccaaaacta tgactatgag ctaaatgaag tattcttcga
     8101 agacttcaag ctaaagaaac ccgattattt tctaaatgca gcaactggta cagcgattga
     8161 aacagttgga aatattttga tcaagatcga tccaattttg gaagaagtaa aaccagatgc
     8221 attcttagta ttaggggata caaatagctg tttatgtgca attgcagcca aacgtcgcca
     8281 tattcctatt tttcatatgg aggcaggaaa tcgctgtttc gaccaacgag taccggaaga
     8341 aacaaatcgt aaaattgttg atcatacagc tgatattaat ctaacctata gcgatatcgc
     8401 gagagaatat ctcttacgtg aaggattacc agctgatcgt gtaatcaaaa caggaagtcc
     8461 gatgtttgaa gttctcaatt caagaaaaga tgacatccaa cattccgatg tccttaatcg
     8521 cttagggttg aaagaaggac aatattttgt tgtttctgct caccgcgaag aaaatatcag
     8581 ctcagaaaca aatttcttac acttggtaga tagcttgaat acaatcgctg aaacttacca
     8641 attgccaatc atcatcagta cgcatccgcg aacaatgaag atgatcgaag caaaagaaat
     8701 caaattccat gagctgatcc aaacaatgaa accaatgggg ttcaatgatt acaataaatt
     8761 gcaaatcaat gcaaaagctg tactaagcga cagcggaacg attagcgaag aatcttccat
     8821 tttgaatttc aaagcattaa acatccgtca agcacatgaa cgaccagaag caatggaaga
     8881 agcaagtgtc atgatggtag gattagaaaa agaaagaatc atgcaaggac tggaagtatt
     8941 ggaaacgcag caaaaagata ctttgcgaca cgtcgcagat tattcaatgc caaatgtttc
     9001 ggaaaaagta ttgcgtatca tcctttcgta tacagactat gtgaatagag tggtgtgggg
     9061 aagatgagaa ttgttgtaaa tgatatcgct gcttcagaag gtggggcaat gtcagtattg
     9121 agagacttac attctgatat aataagtagt ggtgatgaaa atgaatggat ttttttacta
     9181 ggtgaaaaat tcatagaaga aagtgacaat ataaaggtac taacttttcc taaaataaaa
     9241 actagctgga ttaaaagatt ggattttgat tttattagtg gaaaaaaaat tatcaataaa
     9301 ttacagcctg atatctattt atcattacaa aatacagcta ctattggtgt aaaagctcct
     9361 caatatgttt ttttacatca accactacca tatcaaaagg aaaaaaattt ttcgtttata
     9421 aaaaaaaaag agtttaaaat ggctacctat caacatgtta tcggaaagat atattctata
     9481 ttgtttaaaa aaactaaagc tactattata gtgcaaactc aatggatgaa ggaaaatgtt
     9541 tccagtatat taaacaataa aatacttaag gtagatacaa aaataaatat tgatgaaaat
     9601 atcatcaata aacaaataaa tgaaaataaa agaaatatga aacatttctt ttatccagca
     9661 tcaaatattc cgtataaaaa ccatgatttt cttatagaga gtttttcaaa gtgtaaagat
     9721 aaagaattaa gacttttttt aactttatct agagatgaaa ttgatattaa agatgataga
     9781 attatattat taggtaaggt acctagagag aaagtttttg acatatatag taaatcaaat
     9841 ttaatatttc cctcatcaat tgaaacttta ggcttgccat tattagaagc acaatgtttt
     9901 atgagtccaa ttctagcttt agaaacagaa ttctctaaag aagcattgtc cggttacccc
     9961 cataagtatc tatttaaact agataatttg gacaatttaa gtcatttaat agagaaaata
    10021 agtacaagta gtatagtatt taacgttgag aacgtcattt ataagaaaga aaatagagtt
    10081 tctatcttag atatattaaa aggagagaat atttattgaa gaaatttgta gtagcacatc
    10141 cagctcaaca acactcttat aaaatcgctg aagcattaat tgaaaaagaa atgttattca
    10201 aatatattac ttcagtttat ttaaaaaaag gaagtatatt gaataaacta ttaaatatta
    10261 ttccaggaga aaataagtta cgagcgaaag gtcgtcatag tgataaaata tgtgatgagg
    10321 aggtattatt aattaatgaa ttttcagggt tgctacttct tattttacag agggtgaaat
    10381 ttttaaaaca tttatacaaa aaatattggg atttccataa taaaaagttt aataaaaaat
    10441 tgattaaata tataaattcg aatattgatg agatatcggg agtaattgtt tttgatcagg
    10501 tatcctttga tttctttaaa aaaaagatta acattccaat aatactagac atgtctgcac
    10561 ctagtgttgt atttatgaaa agtcaatttg aaaaatatgg aatatcaaca ttgaaatatg
    10621 acgcactctt aaaaaagaat aatttcgaaa tcaatagtgc agattttttc attggggctt
    10681 cttcaataac agaaagatcc ttattaaata tgggaattga aaaaaaacaa ataaaaattt
    10741 tc
//
LOCUS       DAFLWQ010000093        10660 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.096, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000093 DAFLWQ010000000
VERSION     DAFLWQ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10660
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.096"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            332..2278
                     /locus_tag="L1V16_002448"
     CDS             332..2278
                     /locus_tag="L1V16_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1276742.1"
                     /translation="MIERHVNLLKLLSRQEDFKPASFFSDKLAVSTKTIYQDIELLED
                     YVVNYQVTIERLPSLGIKLIGDRKNVEHLISSVENYLEKDIYSPEKRRVEIIKEVLFG
                     DKPVSLTHLSQSFMVSKTSLYNDLRIINKIIGSGEVKLQSSAEGISFTGNEQAIQRAI
                     KQLVFYYANDMESKTFFQVLNMLFDSKVISVIHDLLFNDYSELTEKVSDYYVRSLIST
                     LVIQCNRLLKGHHLTVEEEFLFNSIRYMETYIVANGLIEELKAKLNLPFYDADKEYLC
                     RQLFAHRVTNNLKTSNEEYAMSVHKLIERMSEIEKIDLTQNDRLYQSLLYHVPAMVLR
                     LKKGIKIQNPLLENIKSQYSELFSIVWYAMSILEEEFDVTLTDDEVSLILIHFQIAIE
                     DQSKANNIIIICQYGISSAQLIYNKVRRFLPAKDNVEISTLDKFHLAEIGEVDLIISS
                     LSFDAGGIPLVRVSPLVSKTDYMNIMEAYTKYLIEEPSRFIQNELIPKAVKVPTISKF
                     VQSSLVKTGVQVESKEECLDLMISELEANSLVTEEFRASIFSREKMGNTNLESGVALP
                     HANPSMVIESNIFIVALKNAINWGDRKVKLVIMVSLAEEDVSEIRGVYEELYQFIGQK
                     EMVDRLLQVHDSEKLLRIFQQKGE"
     gene            2281..2736
                     /locus_tag="L1V16_002449"
     CDS             2281..2736
                     /locus_tag="L1V16_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1276743.1"
                     /translation="MYLDKELCLFQLEVKDQKELFQVMSEQLKNAGCVKDSFLEGITN
                     REQEFPTGLEVNQIGFAIPHTDSAHVNSSQICFASLKEPLVFSDMTDKSHEIPVRLVF
                     MLAMSQPHEQIDTLQNLVSLFQNEEKVNELLACTTKEAFIELVHSAGVY"
     gene            2750..4078
                     /locus_tag="L1V16_002450"
     CDS             2750..4078
                     /locus_tag="L1V16_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBN1276744.1"
                     /translation="MDIVLNAFEWFIGLGSNVFLPLIIFVIGILFGLKPGKAFVSGVT
                     VGIGSIGLGLVLSLLSDGLGTAIQQMGEQYGGGLNILDIGVGVGGPLAYSTSLGILMI
                     PISLILNFIFVVLGWTKTLNVDIWNFWFAIFLGMITQSVTGNFWFGLIGAIVAVILQW
                     FLADRTQKTVSEFFGYPGISITHMMGLSGVLFAKPVNWVFDRIPGFNKIDADAETLTK
                     RFGVLGDTVVIGLIIGIVVGIMAGYDVAGIGNLGIMTAAVMKIMPKMVAMFMEGLMPI
                     AEAAKEFTNKKLNGRQVNIGMDAALTVGHPTIMSTSLLLVPISLLLALILPGNKVLPF
                     GDLAFFAFAICLMIPYFKGNIVRSLVGCSLYVVTTLYMATWLAPIITDVFTLASFDVG
                     TAGLVTMLLCGLWPVGLFVLLASYFGVIGIGGLGVVLVGASIYMNKVKKA"
     gene            4112..4396
                     /locus_tag="L1V16_002451"
     CDS             4112..4396
                     /locus_tag="L1V16_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1276745.1"
                     /translation="MKKLLVICGAGHATSTIAVAKLSKWLEEEGLTDQVKIYQSKIAD
                     ELNKIDEYDAVVSTTIVPDVIKAKVTNGLGLLTGIGTDAIYADVKERLGV"
     gene            4398..4913
                     /locus_tag="L1V16_002452"
     CDS             4398..4913
                     /locus_tag="L1V16_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HBN1276746.1"
                     /translation="MRFHHDTLTIETVSGRPSYHDIRKELLDTVDTAGIENGMLVISS
                     PHTTCSLFFEETMHDTNFFGDDYLHVDINNVMETIIPKMTSENQYNSPGPKHIDFGTR
                     LSDPNYPAEKWVMLNTDAHLRSSIYGTNSMTLIVQEGKLLLGEMGRVYFVDWDQLRER
                     TRTINLMIMGE"
     gene            4929..5591
                     /gene="rpe"
                     /locus_tag="L1V16_002453"
     CDS             4929..5591
                     /gene="rpe"
                     /locus_tag="L1V16_002453"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBN1276747.1"
                     /translation="MTIAPSLLNAPIAEVKELFEILKEKNVDYLHIDVMDGCFVPDMA
                     FGPSVIKDIRPLTDVVFDVHLMIDTPEKIVTRFVEAGADIVTFHIEATKHAMKVIQLV
                     KEAGAKVGITFNPATPVSFIEPVLSLVDQVLVMTINPGTENKHFIQETVVKIEQLDVI
                     RKQNDYTYDIEVDGKIDNQTIKVCSKAGADIFVSGGFIFNGKNTPQEQIDKLNQSLEE
                     VK"
     gene            5598..6170
                     /locus_tag="L1V16_002454"
     CDS             5598..6170
                     /locus_tag="L1V16_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1276748.1"
                     /translation="MTNKDQNKNYLEAIILELQNNSKRINSVELEQFSEKIVQAKHIF
                     LAGAGRSGIAMQAFTNRLMHLGFSVSLVGEISSPHSQPGDLLIICSGSGETGSLKNLA
                     AKANQSGVSIALVTMKKDSSIGQLADSVLVLPGITKDENQREEDTFSQPMGSSFEQLA
                     FLTFDSLVLSLMDKTGESSETMFARHADFE"
     gene            complement(6357..7877)
                     /locus_tag="L1V16_002455"
     CDS             complement(6357..7877)
                     /locus_tag="L1V16_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBN1276749.1"
                     /translation="MTKMESELLVQIKQLTQLLEIQQQENTLLREQIAEMNRRLFGRK
                     KETPPVDGQIDLLDDSTFNEPEHTGQESQEPITVSSFKRRKRKGLKALSLEGLPEVPI
                     HYELKGADCLCEDCGHTLHDIGATRLREEPLYVPAHIEKQVIYQHAYHCRECEALGET
                     KIKKAPVPKPLINNSLGSSSIVTQSIWEKFVKKVPAYRQEKEWHALGFPLDRKKITNW
                     HIKVSEMVLEPIYNCLHQELSNQEVLHADETSYRVLNTHKEKTFYWLYASGKSEEKQV
                     VLYEHANSRSVDEPKSFLESFSGFLHTDGYAAYGKLPVNNVYCWAHVRRKFFEALGKQ
                     PSPKSHAKIGLDFCDKMFRIERTFNKLSAEERFVARKETLQPVMTEFFHWCESFAYLP
                     KSQLGKAVQYAVNHKDGLQIVLLDGRLELSNNRAERAIKELVIGRKNWLFSKSLKGAR
                     SNGIILSIIQTAVANGLNIRKYLNHLFTEIPNLSSMTPEALRAYLPWNQQIQEICK"
     gene            complement(8120..8305)
                     /locus_tag="L1V16_002456"
     CDS             complement(8120..8305)
                     /locus_tag="L1V16_002456"
                     /inference="COORDINATES: protein motif:HMM:NF017528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HBN1276750.1"
                     /translation="MPMLIDATALKHIFIVCGKTDLRKGIDGLAAFVIEEYDLDVYDQ
                     ALFLFCGTKKDRFKALY"
     gene            complement(8289..8471)
                     /locus_tag="L1V16_002457"
     CDS             complement(8289..8471)
                     /locus_tag="L1V16_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276751.1"
                     /translation="MNKKDIVPVQFSSAAQKSQIDTKPKLACRIKSEDKEIFIYNGMD
                     KYLLYTLLKELNANAH"
     gene            8712..8930
                     /locus_tag="L1V16_002458"
                     /pseudo
     CDS             8712..8930
                     /locus_tag="L1V16_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            9425..10024
                     /locus_tag="L1V16_002459"
     CDS             9425..10024
                     /locus_tag="L1V16_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1276752.1"
                     /translation="MKTVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLADVLEISRGRVVVKDRLAMKEQKTAKHNSVYISNKLRKTILEYVQQEFPDQ
                     LLQQDFDGYLFPSRKGTNEPLNRQSLWRIIHDAGTAIGLKDIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            10088..>10660
                     /locus_tag="L1V16_002460"
     CDS             10088..>10660
                     /locus_tag="L1V16_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage abortive infection AbiH family
                     protein"
                     /protein_id="HBN1276753.1"
                     /translation="MSTLYIIGNGFDLSHGLKTRYTDFSKWVEKSHSEIFDKIDTMIN
                     ENNEVRSTADDKIGWFNFESSLHELIQSPVFEDYVEESKDYLIGYGHEDWSDSAHHDF
                     QNMVYDYVVSLEELQQLFKEWIRKEIQPTIEHKIPKYQFSSDVLFFTFNYTDVLEILY
                     KQPKENIYHIHGSYDDIIIGHSENFDNFIGD"
BASE COUNT         3525 a         1674 c         1990 g         3471 t
ORIGIN      
        1 aggactcaat tgttcataga tgagcatttg taattaagtt atattataat aaaaaaatac
       61 gaattttagt gacgccatta tattgttttt atttttcaat tgtaatattt catattactt
      121 ccataataag gagtattttc tattggaata tcttagctct tttaaggatt tctccttttt
      181 tgtttctcat tttttaagat tatttggatt tcctttacaa caaacttcca caagtattat
      241 tgacatagat gtaattgagg gaagggggtt ccagtgctag aataaataat gaaaagaggt
      301 aacaaatgct agcgttaaga ggtgaacaag tttgattgaa agacatgtaa atttattaaa
      361 attattaagt cgacaagaag actttaaacc cgcttctttt tttagtgata aattggcagt
      421 gtcgaccaag accatttatc aagatattga attgttggaa gattatgtag ttaattacca
      481 agtaacaatt gagcgattac cttctttggg tatcaaactc ataggtgata ggaaaaacgt
      541 tgaacatttg atttcatcgg tagaaaatta tcttgaaaaa gatatttatt ctccagaaaa
      601 aagacgtgtc gagatcatta aagaagtttt gtttggtgat aagcctgttt ctttaactca
      661 tttgtctcaa agttttatgg ttagtaaaac atcgttatac aatgacctga gaattatcaa
      721 taaaattatt ggcagtggag aagttaagtt gcagtcatct gcagaaggaa ttagttttac
      781 tggtaatgaa caagcaattc aacgagcaat caagcaactt gtattctatt atgcgaatga
      841 catggaatca aaaacatttt ttcaagtttt aaatatgttg tttgattcaa aagttattag
      901 tgtcattcat gatttgctat tcaatgatta cagtgaactg actgaaaagg tttctgatta
      961 ctatgttcgg tcattgattt ctactttagt tatccaatgt aaccgtttac tgaaaggtca
     1021 tcatttaact gttgaagaag aattcctctt caatagcatt cgctatatgg aaacgtacat
     1081 tgtggcaaat ggtttaattg aagaattgaa ggcaaaattg aatcttccat tttatgacgc
     1141 agataaagaa tatctatgtc gtcaactatt tgcacatcgt gtgacaaata atttaaaaac
     1201 cagcaatgaa gagtacgcta tgagcgttca taaattgatt gaaagaatga gtgagattga
     1261 aaaaattgat ttgactcaaa atgatcgatt atatcaatcc ttattgtatc atgtgccagc
     1321 aatggtcctt cgtttaaaaa aaggtattaa aattcaaaat ccgttattag aaaatatcaa
     1381 atctcaatat tcagaactct ttagcatagt atggtacgcc atgtccatcc ttgaagaaga
     1441 atttgatgtg actttaacgg acgatgaagt ttccttaatt ttgattcatt ttcagattgc
     1501 tattgaagat cagtccaaag caaataatat catcattatt tgccaatacg gtatttcttc
     1561 tgcgcaatta atttacaata aagttcgacg gtttttacca gcaaaagata atgtagaaat
     1621 atcaacttta gataagtttc atttagctga aattggggaa gttgatttga ttatttcctc
     1681 tctttccttt gatgcaggtg gtataccctt agtaagggta tctccattgg taagtaaaac
     1741 agattatatg aatattatgg aagcttatac taaatattta atagaagaac cttcgcgatt
     1801 tattcaaaat gaactgattc ctaaagcggt taaagttccc accatatcta aatttgttca
     1861 atcatcttta gtaaaaacag gagtacaggt ggaaagcaaa gaagaatgtt tggatttgat
     1921 gatttccgaa ctagaagcca attcattagt tactgaagag tttcgtgctt ctatcttctc
     1981 tagagagaaa atggggaata ctaatttaga aagtggtgtt gctttaccgc atgcgaatcc
     2041 atcaatggtc attgaatcca acatttttat tgtagcatta aaaaatgcga ttaattgggg
     2101 cgatcgaaaa gtcaaattag tcattatggt tagtttagct gaagaagatg tatctgagat
     2161 tagaggagta tatgaagaac tttaccaatt tattgggcaa aaagaaatgg tcgatcgctt
     2221 gttacaagtt catgatagcg aaaaattact aagaattttt caacaaaaag gagaataaaa
     2281 atgtatctag ataaagaatt atgtttattt caattagaag tgaaagatca aaaagaattg
     2341 tttcaagtaa tgtctgaaca attaaaaaac gctggttgcg tgaaagatag tttcttagaa
     2401 ggtatcacca accgtgaaca agaatttcca actggattag aagtaaatca aattgggttt
     2461 gctatcccac atacagattc cgcacatgta aatagctctc aaatctgttt tgcctcatta
     2521 aaggaaccac tggtattttc agatatgaca gataaatctc atgaaatacc tgtacgttta
     2581 gtctttatgt tggcaatgtc acaacctcat gaacaaattg atacactaca aaacttagtt
     2641 agcctatttc aaaatgaaga aaaagtaaat gaattacttg catgtaccac gaaagaagca
     2701 tttattgagt tagtacattc tgcaggagtt tattaggagg aatagagaga tggatattgt
     2761 attaaatgcc tttgaatggt ttattggatt agggtcaaac gtctttttac cactgattat
     2821 ttttgtaatc gggatattat ttggattaaa acctggtaaa gcatttgttt ccggcgttac
     2881 tgttggtatc ggttctattg gtttaggatt agttttaagt ttattatcag atggtttagg
     2941 aacagcaatt caacaaatgg gggaacaata cggtggtggc ctgaatatcc tagatattgg
     3001 cgtaggtgtt ggtggacctt tggcttactc tacatcattg ggaattttaa tgattccaat
     3061 ttcattaatt cttaacttca tatttgtggt tttgggttgg acaaaaacat tgaatgttga
     3121 tatttggaac ttttggttcg caattttcct aggtatgatt actcaatctg ttacgggaaa
     3181 cttttggttt ggcttaattg gcgcgattgt cgcagtaatt ttacaatggt tcttagcaga
     3241 tcgtacacaa aaaactgtta gcgaattttt cggctatcca ggaatctcta tcacacatat
     3301 gatgggatta tcaggagtac tatttgccaa accagtaaat tgggtttttg atcgtattcc
     3361 tggatttaat aaaatagatg cagatgcaga aacattaaca aaacgtttcg gtgttttagg
     3421 tgacacagtt gttattggcc taattatcgg tattgtagtg ggtattatgg caggctatga
     3481 cgtagcagga attggaaact taggaattat gactgcggca gtgatgaaga ttatgcctaa
     3541 aatggtagca atgtttatgg aaggtttaat gccaattgca gaagcggcga aagaatttac
     3601 gaataaaaag ttaaatggtc gccaagtaaa cattggaatg gatgcagcgt taactgtggg
     3661 tcatccaact attatgtcaa cttctctatt gcttgtacca atctcattat tgctagcact
     3721 aattcttcca ggaaataaag tattaccttt tggagattta gcattctttg ctttcgccat
     3781 ctgtttaatg attccttatt ttaaaggaaa tattgtgaga tcattagtag gatgttcgtt
     3841 gtatgttgtt acaacattat atatggcaac atggttggca ccaattatca ctgatgtgtt
     3901 tacattagca agtttcgatg tggggacagc aggattagta actatgttgt tatgtggatt
     3961 atggccagta gggttgtttg ttttattagc atcttacttt ggtgtaattg gaataggtgg
     4021 attaggagtt gttttagtag gtgcttctat ctacatgaac aaagtgaaga aagcttaatc
     4081 ataaaattaa aataagaaag aagagatcaa tatgaaaaaa ttattagtta tttgtggagc
     4141 aggtcatgct acttctacaa ttgcagtagc aaaattatca aaatggttgg aagaagaagg
     4201 attaacagat caagtgaaaa tttatcaatc taaaattgct gatgagctaa ataaaattga
     4261 tgaatatgat gctgtagtaa gtacaacaat tgtccctgat gtaattaaag ctaaagtaac
     4321 gaatggcttg ggcttattaa caggtattgg tacagatgcc atttatgcag atgtaaaaga
     4381 aagattaggt gtttaatatg cgttttcatc atgacacttt gactattgaa acagtttcag
     4441 ggcgtccttc gtatcatgat attcgaaaag aacttttaga tacagttgat acagcaggta
     4501 ttgagaatgg aatgttagta atttcgagcc cgcatacaac ttgctcactc ttttttgaag
     4561 aaacgatgca tgacacaaac ttttttggtg atgattattt acatgtagac atcaacaatg
     4621 taatggaaac gattattcca aaaatgacga gtgaaaatca atacaacagt ccggggccaa
     4681 aacacattga ttttggaaca agattatctg atcccaatta ccctgcagaa aaatgggtca
     4741 tgctaaatac cgatgcacat ttacgttcat ctatttatgg aaccaactca atgactttaa
     4801 ttgttcaaga aggtaaactt ttattaggag aaatgggccg tgtctatttt gtcgattggg
     4861 atcaactaag agagcgaact agaacaatca atctcatgat tatgggagaa taaacggggg
     4921 aatagagaat gacaattgct ccatcattgt taaatgcacc tatcgcagaa gttaaagagt
     4981 tatttgaaat cttaaaagaa aagaatgttg attatttgca tattgatgta atggatggct
     5041 gttttgtacc agatatggct tttggaccaa gtgttattaa agatattcgt ccactaacag
     5101 acgttgtgtt tgatgttcat ttgatgattg atacaccaga aaaaattgtc acaagatttg
     5161 tagaagcagg agcagatatt gttaccttcc acattgaagc taccaaacac gcaatgaagg
     5221 tcattcagtt agtcaaggaa gcaggagcaa aagtagggat tacttttaat cctgcaacac
     5281 cagtcagttt tattgaacca gtattatctt tagtcgatca agtattagta atgacaatca
     5341 atccaggaac agagaataag cattttattc aagagacagt agttaaaatc gaacagttag
     5401 atgtaatacg caaacaaaat gattatacgt atgatattga agtagatggc aagattgata
     5461 atcaaacgat taaagtttgt tctaaagcag gggcggatat ttttgtatca ggcggtttca
     5521 tcttcaatgg gaaaaatacc ccgcaagaac aaattgataa actaaatcaa tcattagagg
     5581 aagtgaagta aaagatcatg accaataaag accaaaataa aaactattta gaagcgatta
     5641 tcttagaatt acaaaataac tcaaaacgta ttaattctgt agagttagaa caatttagtg
     5701 agaaaattgt tcaagctaaa cacatctttc tagctggtgc aggacgctct ggaattgcca
     5761 tgcaagcatt tacgaatcgc ttaatgcatt taggtttttc agtcagcctt gtcggtgaaa
     5821 ttagttcacc acattcgcaa cctggagatt tattaattat ctgttctggc tcaggtgaaa
     5881 caggtagttt aaaaaattta gcggccaaag caaatcaaag tggtgtaagc attgctttag
     5941 ttaccatgaa aaaagactcg tcgattggtc aattagcaga ttctgttctt gtattaccag
     6001 gtattaccaa agatgaaaat caacgagaag aagatacttt ttcacaacct atgggttcaa
     6061 gttttgaaca attagcattt ctcacctttg atagtttagt gttatcttta atggataaaa
     6121 caggtgaaag ctcagaaacg atgtttgctc gacatgcaga ttttgagtag tagattttaa
     6181 agataaaaaa ccattctcta aatgctaatt attcagcaaa tatgagaatg gtttttttat
     6241 ttgattagac ataacttaat aattcagtag ttttgagcgt aagcgtgtca tagaatggta
     6301 cctaaacaca aatagcccga tttgatacac tcaaatcagg ttatttgtgg cttatattat
     6361 ttacagattt cttgtatctg ctgattccat ggcaaataag cgcgtagcgc ttcaggtgtc
     6421 atcgaagaca gattgggaat ctctgtaaaa agatgattta aatatttgcg gatgtttaac
     6481 ccattcgcaa cagctgtctg gataatactc aatataattc catttgatct agcgcctttt
     6541 aagcttttag aaaatagcca gttttttcga ccgatcacta actctttgat ggcacgctct
     6601 gctcggttat ttgaaagttc caagcgtcca tcaagcaaca caatctgaag tccgtcttta
     6661 tgattgactg cgtattgaac cgcctttcca agctgcgatt ttggcaaata agcaaaactc
     6721 tcacaccaat gaaaaaattc agtcatcaca ggctgcaacg tttccttcct cgctacaaac
     6781 ctttcttctg cgctaagctt attaaaggtc cgttcgattc gaaacatctt gtcacagaag
     6841 tctaatccta ttttggcatg actttttggg gacggttgtt tacccaatgc ttcaaaaaac
     6901 tttctgcgaa catgcgccca acaataaaca ttgtttaccg gcagctttcc ataggccgcg
     6961 taaccatcag tatgcaagaa accgctaaat gattctaaaa aactttttgg ctcatcaacg
     7021 gaacgcgaat ttgcgtgctc gtagagcaca acttgttttt cttcgctttt acctgaagca
     7081 tataaccagt aaaaggtctt ttctttatga gtattcaata cccgatagct tgtctcatcc
     7141 gcgtgtaaga cctcctgatt gcttaattct tgatgaaggc aattgtagat tggctctaaa
     7201 accatttcac ttaccttgat atgccaatta gtgatttttt tacgatcaag agggaaacca
     7261 agtgcatgcc attctttttc ttgtcgatat gccggcacct ttttaacaaa tttttcccaa
     7321 atactctgtg tcacaattga agaggaacct agactattat tgatcaacgg tttaggaaca
     7381 ggcgcttttt tgatttttgt ttctcctaat gcttcacatt ctctgcaatg ataggcatgt
     7441 tggtagatga cttgtttttc tatatgggca ggaacataca atggctcttc tctaagcctt
     7501 gtcgcaccga tatcatgtaa agtatgacca cagtcttcac acaaacaatc ggcacctttt
     7561 aattcataat gaataggaac ttcaggcaga ccttctaatg aaagtgcttt gagtcccttg
     7621 cgttttctgc gtttaaaaga agataccgta atgggttcct ggctttcttg tccagtgtgc
     7681 tctggttcat taaaagttga gtcgtctaat aaatcgattt gcccatctac gggtggtgtt
     7741 tctttttttc gtccaaacaa gcgtcgattc atttcagcaa tttgttctct aagaagagta
     7801 ttttcctgtt gctggatttc aagcaactgt gttaattgct tgatttgtac aagaagttca
     7861 gattccattt ttgtcatttt tacaccacca ttctagcgat tttcttacat ctattatacc
     7921 attttatgac aacgaaaaac agacaaaatc cttgatttaa caaggttttc gtctaatata
     7981 tcgcaccttt tttcgtttct tttagcgtac atttttcttc gattgaaagg ccagtcagta
     8041 agacttcttt tctggaacgc ggccattgaa ggtacccact ttcaaatctt ttgtacatta
     8101 atacaaatcc attttgatcc tagtaaagag ccttgaagcg atctttcttc gtaccgcaaa
     8161 ataagaaaag cgcttgatcg taaacatcaa ggtcatattc ttctataacg aaagctgcta
     8221 gtccatcaat tccttttcga agatctgttt ttccacaaac gataaaaata tgtttcaatg
     8281 cagttgcatc aatgagcatt ggcattcaac tcttttaaca aggtatacaa aagatattta
     8341 tccattccat tataaataaa tatttcctta tcttccgatt tgattctgca agctagtttt
     8401 ggcttggtgt caatttgcga tttttgagcc gcacttgaaa attgaactgg tacaatatct
     8461 tttttattca ttcgtttttc tccttctata tttgatagtt taattataga agaaagataa
     8521 tcggcgtacg agatactatc ctatgacacg cttacattta atttaatatt ttgcctcaaa
     8581 ttagccacac tttttataga actaagagga aaaatgaagt tttcttccta ttaatatagt
     8641 tgtttgaaat cttaaatata gcgttttacg atgtaatggg aagtatggtg aataaatcaa
     8701 ctatgttcgt acgaagcatt tactcaacta atttaatcga atctttcaat aaacaaatca
     8761 agaaatacag ccaccgcaag gaacagttcc aaaatgaaga gtcgatggaa cgtttcttag
     8821 tctcgtcttt tgatacttac aaccaaaaat tcctaggtcg cagtcataaa ggtttccaac
     8881 aggccgaagg cgagctcgaa caaatgctga gtcaaccgat ggagaattag aaacaatcta
     8941 cagtagggaa gaaccattga cacaaaatta ttgacgctcc caactaaaag tgtcaaaata
     9001 atgatgaaat catttagttc ttataaatta gaaaagagaa aataaatatt ccatatctac
     9061 tttattggat ccgtaacatg actaaattct gaatactttt taaagcttat catttggtaa
     9121 aactgaatat aagttaatta tatagactga aaattttgaa ttttcagaat agaataactt
     9181 aaaagtactg acaaaatttt ttaaaggggc aatattaatg ttctgagata atcaaatcct
     9241 accgaaaata tcaaaaatcc aatgtgacac aatcagattg tgtctcattc gagggaatca
     9301 cacaatccca cgtggctcta ggcagaattg aatttttgct tggggctttt tccttatatt
     9361 gattttgaat gagacttatt atatgttata atgcaattaa gtatcattgg agagggcgaa
     9421 gaaaatgaag acggtagaac ctattcgaga caaaaaaaag atcgatgcga tgaaggcaat
     9481 cttggcttcg ggaaaatatg gccaacgaaa tttggttctt ttttcgattg ggatcaacac
     9541 cgcctatcgc atttctgatt tgcgtcaatt gaagctggcc gacgtgctgg aaatttcacg
     9601 cggtcgcgtg gtggtcaaag atcgattagc gatgaaggaa caaaaaacag ctaaacataa
     9661 ttcggtctat atttccaaca aattgcgaaa aacgattttg gagtacgttc aacaggaatt
     9721 tcctgatcaa ctccttcagc aagattttga cggttatttg ttccctagtc gaaaagggac
     9781 gaatgaaccg ctcaaccgcc aaagtctgtg gcgaatcatt catgatgctg gcacggcaat
     9841 cggattgaaa gacattggcc cacattccat gcgaaaaacg ttcggttact ttctctataa
     9901 acaggggacc aaaacagaaa tcattcagtc cttgttgaac cattcttctc agcgcgaaac
     9961 attgcggtat attggtatta cacaagaaga caaagataca gctgtaaaaa gcttagattt
    10021 ataatataaa agttaagttt aaacatggat agttttaaat tagtagattg agtgttggga
    10081 ggaaagaatg agtacattat atattatagg aaacggtttt gatttaagtc atggtttaaa
    10141 aactagatac actgattttt caaaatgggt tgaaaaaagt catagtgaaa tattcgataa
    10201 aatagacaca atgataaatg aaaataatga ggtgagaagt acagctgatg ataagatagg
    10261 ttggtttaat tttgaaagta gtttgcatga gttaattcaa agtccagtct ttgaagatta
    10321 tgtagaagag tctaaggatt atctcatagg ttatggacat gaagattggt cagattctgc
    10381 ccatcatgat tttcaaaata tggtttatga ttatgttgtt tctctagaag aattacaaca
    10441 acttttcaag gaatggatac gcaaagaaat acagccgaca atagaacata aaattccaaa
    10501 ataccaattt tcgtccgatg tactattctt tacattcaat tatacagatg ttttggaaat
    10561 tctatacaag caaccgaaag aaaacatata tcatattcat ggcagttatg acgatataat
    10621 aatcggccac tccgagaatt ttgacaactt tataggagat
//
LOCUS       DAFLWQ010000094        10498 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.097, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000094 DAFLWQ010000000
VERSION     DAFLWQ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10498
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.097"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            34..657
                     /locus_tag="L1V16_002461"
     CDS             34..657
                     /locus_tag="L1V16_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276754.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1107..2156
                     /locus_tag="L1V16_002462"
     CDS             1107..2156
                     /locus_tag="L1V16_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1276755.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2153..3034
                     /locus_tag="L1V16_002463"
     CDS             2153..3034
                     /locus_tag="L1V16_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1276756.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3037..3807
                     /locus_tag="L1V16_002464"
     CDS             3037..3807
                     /locus_tag="L1V16_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1276757.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4086..4940
                     /gene="aroE"
                     /locus_tag="L1V16_002465"
     CDS             4086..4940
                     /gene="aroE"
                     /locus_tag="L1V16_002465"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBN1276758.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5118..6281
                     /locus_tag="L1V16_002466"
     CDS             5118..6281
                     /locus_tag="L1V16_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBN1276759.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6398..6808
                     /locus_tag="L1V16_002467"
     CDS             6398..6808
                     /locus_tag="L1V16_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1276760.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6982..9210
                     /gene="topB"
                     /locus_tag="L1V16_002468"
     CDS             6982..9210
                     /gene="topB"
                     /locus_tag="L1V16_002468"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBN1276761.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9381..9655
                     /locus_tag="L1V16_002469"
                     /pseudo
     CDS             9381..9655
                     /locus_tag="L1V16_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9815..10051
                     /locus_tag="L1V16_002470"
     CDS             9815..10051
                     /locus_tag="L1V16_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBN1276762.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10048..10446
                     /locus_tag="L1V16_002471"
     CDS             10048..10446
                     /locus_tag="L1V16_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBN1276763.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3661 a         1764 c         2226 g         2847 t
ORIGIN      
        1 taataaaaaa taggagaaaa agtagaaaag aaggtgtttg ttatttggga agtagttaaa
       61 tcgagagtac aagaaatgaa tgaacatttc tcagtgtcat tcgcagaaaa tccaagtaag
      121 tattttcgac gtcttgtttt tctgctcatc ttatcattgc tgttaacagt tgcaatgttt
      181 ttattgccgg aaaaaatccg agaagagcaa gtaaatagtc tcgtttattc gtccatacca
      241 accagcaaat tgaaaccttt tgattacagc aaagctgatc agaaaatcaa acaaagccgg
      301 gcgatatcgg tgatgttcag caaaccgaac gggaaaacct atcaggacat gcttgatgtt
      361 tttaatgatc ctgagcttat ggaagaattg aatcgaccga tcttttatta tccgatcgtt
      421 tatgatgtac atgaactgga acaaaaatat aacatacgaa cggatgaagt gacatttatt
      481 ttctttgatg gaggaaaaga agcaaatcgg ataactgcgg gtaagggagg aataactgat
      541 tttgataagg agttgatccc tgaactgaat cgacttccgt tagccaatat caaacaatta
      601 gaagaagaat tggatagaac gggagtaact tcccaaaatt ccgagattgc taattgagac
      661 attggcgcga tgaaacggtg ggtctatata gcgctatttt taattatcag aacaagtgat
      721 gtttgatctt caaaataaca aataaaaaat taaaaaatat agttgacgaa attcaaaaat
      781 tcgattagac ttaaatcaat tcttaaggaa agggtgacct gtaatgaact tatcaaaacg
      841 tatttcagca gaaaacaaaa aaaattggcg cagctggcgt agataagttg tattaatggt
      901 gagactttcc catagataca actttttaga gtgcatttct aaagcttgta tctatgctag
      961 acatgaacat tgactgccgc atagattaga atctatgcgg ttttttgtgt aaagacaatg
     1021 accgctttgg ccattgtctt tttttgtaga ctggatactt gcctgattat aataaataaa
     1081 aagattgact ttgcaggagg aaaaaaatga aaaacaaacg attaataaca gttgtagtaa
     1141 ttattttagt ttatttagca ggtgcattta tttatggaaa agcctcaggc gaaaaagaaa
     1201 gtacttcgac gaaccagaca aaaaaaacaa cagttgttgg ggtattgcaa tacgtgagcc
     1261 atccggcatt agatgagatt tatcgaggaa tcaaagatgg tctgaaagaa gaaggattaa
     1321 aagaaggaga aaatcttgag atcaaatttc aaaatggaca agccgatcag agcaagctag
     1381 ccacaatgag tcaacagcta gtacaatctg atccagatgc cttgattgga atcgcaacac
     1441 ctgccgctca atcattagca aacacgactt catcgatccc agttgtgtta ggtgctgtaa
     1501 cggatcctgt gggggctgga ttagtcgctt ctttagagaa acctggtggt aatgtaacag
     1561 gtgtttctga tcagccgcct gttacttcac aaatcaagct tgcttctgat ttgttgccaa
     1621 atgcaaaaaa agtcggaatc ttgtatgctt cttcagagga taattcaaaa taccaagtag
     1681 cacaagcaga agaagctgca aaaaaagaag ggttagaatc agtaaaatat gcggtgcctt
     1741 ccactaatga gattgcacaa acggttcaag tgatgagccg acaagtcgat tttatctatg
     1801 ttccattaga taataccatt gccaatgcga tgcaaacagt ggtaaaagaa gcaaacaaag
     1861 caaatatccc cgtcattcca tctgtggata caatggtgga acaaggtgga ctagcaacaa
     1921 tcgggatcaa tcaatatcaa ttagggcttc aaagcggtaa gatggcggca gaacttgcga
     1981 gtggaaaaga aaaaccggaa acgacgcctg tttatacatt tgatcaaggg gatacagtga
     2041 tcaatcaatc tcaagctgat cgcttaggaa tcattgttcc ccaatcgatg aaggaaaaag
     2101 ccaaaatcat tacagatgac tcgcagcaag aaacatctaa ggaggatgac aaatgatcgt
     2161 atcagctatt tcacaaggca tgctttgggc aatattagga ttagggattt tcatgactta
     2221 tcggatctta gactttcctg atatgacgac agaagggtcc ttcccattag gtgctgctgt
     2281 ctgtgtgaca gctattactc atggggtagc gccgattgta gctacattat taggcgtagg
     2341 tgctggcatg atagcaggac tcgttacggg gttactttat acaaaaggaa agataccggt
     2401 tattttagca gggattttag tgatgtcagg attgaactca gttattttgt ttgtgatgcg
     2461 aacaccaaat ctttctttat tgaatcatcc gattctacaa gacagcttcc atcgctttgg
     2521 gttacctgat tactttgaca cagtccttct tggcttcatc tctttgggca tcttgattgc
     2581 tgtactgcta ttcttcttca atacagattt gggtcaaggc tatattgcga caggagacaa
     2641 cgaaacgatg gctcggtcgt tagggataaa aaccgatcgt atgaaaattt taggtttaac
     2701 tttgtcgaac ggtgtcattg cattatccgg tgcgctgatt gcccagaacg acggatatgc
     2761 agatgtaaat aaagggattg gcgtaatcgt catcggtctt gcttccatca tcatcggtga
     2821 agtgatcttc caagaattga cgctagcaga aagattgatt gctattgttg tcggcagtat
     2881 catttatcag ctattgattt tagtagtaat caaactaggg tttgacacga cttatctgaa
     2941 gttgttctcc gctatcatct tagctatttg tctgatgatc ccgcaattga agaaagcact
     3001 gaacttaaaa acgggttttg agaaggaggc atagtaatga ctgatatatt gacaatcaaa
     3061 aatggcagaa aagtcgtaaa caatggaatg aatgaagaga aagtactatt ggatgaaatt
     3121 aaccttacaa tcagagaagg ggacttcatc actgtccttg gcgggaatgg tgctggaaaa
     3181 agcacactgt tcaatacgat cgctggtacg cttcaactca gtcaaggatc gatctctttt
     3241 aaagatcagc tgatcacaaa agattcagaa gaaaaaagag cacgattcct ttctcgagtt
     3301 ttccaagacc ccaagatggg aacggctcct cggatgacag tagcagaaaa tttgctactt
     3361 gcacaaaaaa gaggtcaaaa acggaaattc cgtttacgta acttgaaaaa tcaaaaagaa
     3421 gattttttca gactatgtca agaagtcggt aatggcctag agcaacactt ggatactcca
     3481 gcgggtgaat tatctggtgg tcaacgccaa gcattaagct tgctgatggc gacgatcaca
     3541 gctcctgagt tactattatt agatgaacat actgcagctt tagatcctaa aacagctaaa
     3601 gcattaatgc gattaacaaa tcagcggatc aatgaacaaa aattgacttg tctcatgatc
     3661 acgcatcgaa tggaagacgc cttgaaatac ggaaatcgtc tgatcgtact ccaaaaaggg
     3721 aaaatcgttc aagatatttc tgaaaaagaa aagcaacatt tgacaatggg cgaccttttg
     3781 cagttctttg aagaagtagt ggattgattt cgacagaaaa attcctttca gtagaaggac
     3841 ttgaaaactc attgacatct tcctttgatt catcctatac ttaaaacaat aaacaattaa
     3901 acatatttgg gtgttttgta ggatcacgta gtcaatgatt ttaacaatta aatagaatat
     3961 tctttgctct gacaagtaaa cgatgagaaa agaatttgct actttgccac ctagacgttt
     4021 cgtacttttt cgtatcaaac gctaagtggc tttttttatt gaagtaagaa caaaggagga
     4081 ataagatgat ttctggacaa accaaattag ctgggctctt tgctgatccg gcttctcaca
     4141 gtttatcccc attgatgcac aatactgctt ttgaagcaaa caacatcgat gcggtgtatt
     4201 tagctttcca agtaaatcca atgaatttga agcaagcagt cgaaagtatt cgaacttttg
     4261 atatgttagg tgtaaatctt tcgatgccga ataaaacagc ggttattcct tatctggatg
     4321 aggtaagcca ggaagcgcaa ttgatcggag cagtgaatac gatcgtgcac gaaaagggtc
     4381 gtttgattgg ctataatacc gatggtgcgg gcttcatgca atccgtgcaa gaagctggga
     4441 tttcgatcaa aaagaaaaaa atgactctac tgggagctgg aggtgcagca aaggcagtca
     4501 ctgttcaagc tgcgttagac ggcgctgagg aaatcgtagt ttataaacga aacaaccaaa
     4561 cattcgctca agtaaaagaa acattcgaac aactcagcta tcgaacttct tgtaagataa
     4621 aagttcgtga ctttgccgat acgcatcaat taagaaaaga cttgaaagaa agctgtcttc
     4681 tagtcaatgc aacagatatc gggatgggaa agaaaatcaa tcagtcaccg ctcttagata
     4741 taagcatgat gcatgagaat ctagcggttt ttgatttgat ttatgcacct agagaaacac
     4801 gtttattaaa agaagcaaaa aaagtaggag caaaaggata caatggactt ggcatgttga
     4861 tctaccaagg agcaatcgcg tttgaattat ggacaaagga aaagatgccg atccatgtga
     4921 ttgaaaagct gtttgattaa aaaaggataa tagataaaga tcttttattc tcgcataaac
     4981 ggtctcaaga aaagtaatcc tttatgtatc gaagcattta tttcgttatt ttttattaaa
     5041 ttatcaaaaa atgataggct tttgtcgatt ggttatcgta tcctttattt atcagtaaga
     5101 aacgaggagg aaccacaatg agtcggatgg atcgctataa ggacatccat aagaaggcga
     5161 aacctctgaa gcgggatacg gggagtattt ttgctagaag agaacgaaaa cgaacgcgta
     5221 tggaaaatga ggaagatgct acccgtattt atgaaagaga gcagcattca tttgaacatt
     5281 tgaaccaata cgagcaacag atatacagag atgcaccaag agcagaagaa caacaaaaaa
     5341 ataaaaaatt tttcaatcgg caaaagaaga acaaaccgtt aaaacctcga agaaagcgat
     5401 cgtggaaaaa aatcattcta tcgattttgc ttgttttgat cctttattca ggtatctcat
     5461 tttttattgg taaatatgta gctgaacatg acacaagctt agaggcagcg acttcagaaa
     5521 cctttcatgg gcaaaaagcg acgaatggtg cgcataatat tttgatcctt ggaagtgata
     5581 cacgcggaga agatgccggg cgagccgata cgatcatggt cttacagttg gatggtcctt
     5641 cccataagcc gaaactgatt tcttttatgc gtgacagctt cgttacgatc ccaggggtag
     5701 gacaaaataa gatcaattca gcttatgcat acggaggagc cgatctagtg cgtcaaactt
     5761 tagtagaaaa ttttggaatc gattgtcaat actatgcgaa agtcgatttc aaatcgtttg
     5821 aaaaagtgat cgatgcctta ttcatgaacg gagtgaagat cgatgcagaa aaagatctga
     5881 atctggatgg tgtagatatt aaaaaagggg tccagaagat ggatggacat gttcttttgc
     5941 agtacgcacg tttccgaatg gatgaacaag gagactttgg ccgtgtcaga cgccaacagc
     6001 aagtaatgaa cgctattttc agccaattga agaatccatt gaatctgatc cgtgcacctt
     6061 atgcagctgg taaagcttta ggatatacat ccacagatgt cactgcttgg ttcttgacga
     6121 aaaacctctt ttcgattgca cgaggagctg gtggcattga tcgaataagt gtgccagtag
     6181 acggttcgtg gaattatggg caaagtgatt atgctggcag tattcttgaa attgataatc
     6241 aaatgaatca atctgctatt acagattttt tgaataaatg atcataaaaa agatcaagaa
     6301 gaagctgcgc aaggcttttg tcatgaatca atcaaacgat tcactcgtaa aaaacgcttt
     6361 cttatggtag atttaaccaa gagaggagct gtttacattg gatatctatc tgaacttcaa
     6421 aaatgagtcg cgtgaagcca tcgcttttta tgaaaaagtt tttcagactg aagcatcagg
     6481 tatcaccaca tacggtgaaa tgcctggaat agaacaaatg aacttgccag aagaagcaaa
     6541 aaatctaatc acgaatgcac ggctgaacat ttatgataca ttagttatgt ttgcagatac
     6601 gccagaagga attggtcctg aattagttgt gggaaataat gtttctttag tcatccagac
     6661 aagaaatgaa gaagaaacga agcgcctatt tgaaagctta gctgagggtg gtaagattga
     6721 gatgccactg gatgctgttc cgtgggctca gttgtatggg atggtaactg atcgatttgg
     6781 catcaactgg cagattaacc aagagtgaca gctaaagatg aatattttct ggaaacatca
     6841 agcagcaaac ggatcatcgt ttgtttgctt gatgtttttg tgtctatttc gactatacgg
     6901 tatctttttt ttattgccag atgcgaaaat atgttccata atagagaagt ccgcaaaaaa
     6961 ttaagtaacg gaggtcagaa gatgaagacg gtgatactag ctgaaaaacc ttcacaagca
     7021 aaagcctatg ccgaaacctt ccaacagcaa aagcggcatg aagggtatta tgaaatcagc
     7081 gatccattgt ttgctggtga agtaaccatc acttatggtt ttggacattt ggtagatatg
     7141 gttgctccag gagcttatga agagcgttgg gcaaaatggt ctttagaaaa tttgcctatt
     7201 ttcccagaaa ccttccgtta cgaagttcca atggacaaac gtgcacaatt ttcgatcgta
     7261 aaacgagaat tgcagtcagc cgataccatc attattgcaa cagatggtga tcgagaaggt
     7321 gaagccatcg cgtggtcgat tattcgacaa gcaaacgcat tttctaagga aaagaactat
     7381 ttacgtttat ggatcaattc tcttgaaaaa gaagcaatct atgaaggttt taagaatctc
     7441 caacctggaa agaactattt tccaaaatat aaagaagcgc aagcaaggca gaacgctgat
     7501 tggctgattg gaatgaatgg aagtccatta tatagcttgc tacttcaacg aaaagggatt
     7561 gatggcagtt tttctcttgg tcgtgtacaa acaccgacac tctatatgat ttatcagctg
     7621 caagaagaaa tcaaacactt caaaaaagaa acgtactttg aaggagaagg tttaattacg
     7681 acaaacaaag ggcagttttc tggaaaaatc gtaccaaaaa aagcatttaa aacccaagaa
     7741 gagttaacga aggaaataga aaaacttgga gcgcatttag gtaagcaaaa cggacggatt
     7801 cttgaagtta cgaaaaagga aaagaggttg catagtccac gtttattttc gctatctagt
     7861 ttgcagacaa agatgaatca gctaatgaaa gcaagtgcca aagctacact tgatgctgct
     7921 caaggattgt acgaaagcaa gtttctaagc tatccaagaa cggattcctt ttacattaca
     7981 gaaaatgagc atcagtatct ggttaaacat ctgcaaaatt ataaaaaatt tttaggaata
     8041 gaagaagtac agacaactga gatcaaagca aagaaacgat atgtcgatgc gaaaaaagtt
     8101 caagaacatc atgcaattat tccgacaaag acgattccga ctcctgcacg ctttgcgaag
     8161 ctttccaaat tacagcaagc aatctatttg caagttttgc gcactactgt ggctatgttt
     8221 gctgcagatt atatctacga agagacgacc gtaatgacgg gcgtacagca attaaagcta
     8281 aaaagcatcg gaaagatccc attacagcaa ggttggcagg aaatcttacg catcaagtca
     8341 aaaaagaaag aagctcagac tcttcctcct atcgtagaaa atgaagaagc agaagtagaa
     8401 ctgaaaagta tggagaaaga aacacaacct ccaaaaccct ataccgaagg aacgttgatc
     8461 acagcaatga aaactgcggg aaaaacgctg gataatgatg aagcgcaaga aattctcaaa
     8521 gaagtagaag gaatagggac agaagctaca cgagccaata tcattgaaaa tcttaagcag
     8581 aagcattaca tcgaagtcaa taaaaacgaa ataactgtta cgccaaaagg aatcactctt
     8641 tgtaaggcag tagccaatga accattactg acgagcgcag aaatgactgc gcgctgggaa
     8701 gggtacttga gaaaaattgg taaacaagag gggacaccat ctgttttttt agagaatatc
     8761 aaaaaattca tcctacattt attggcagaa gttcctaatc aaatcgacaa ggtagacttt
     8821 tcagatgaga ttagcgggac acgtcagata aaagcgatgg agaagaaaaa cgatcaatta
     8881 ggaagatgtc caaaatgtaa aaagggaata gtcatgcttt atcctaaaat cgctacatgc
     8941 ttgaatccgg aatgcgactt caaattgtgg ccaacagtag ctaaaaagaa gctgactaaa
     9001 acgaatctca gagatttgct ttcaaaagga aagacaagta aagttgtcaa aggttttact
     9061 ggtaaaaaag ggaaattcga tgcagtttta gtattaaaag aagatatgac aatcggtttt
     9121 tcttttccat ggatcgaaaa cagtggaaca aaagcagttg atggaaacaa agaaacatca
     9181 agaaaaaata atgaaaacga agtagagtaa atgaaaacaa tgaaatagcg gaatatttat
     9241 tccgaaaagt gagaatataa ataccaataa aactaaaaaa tatcagtgaa tcaagcaaaa
     9301 acgttggggt aggctgattt tatatagata gcaaggagtt tttttatttg aaaaaagtgc
     9361 attcattttt aaattatctt atgggagcaa tcacgattgt ggctgtgtac caaggtatcc
     9421 tgattacggg acgaagttgt tgtcattgac gcacaatcaa acagcatatt caccaacgtt
     9481 gattttatcg actttgactg caggagctaa aagcgctact tatttttttc ataaaacgac
     9541 aagcatgcta aagcgaaaga aacagcgaaa acaattgttg gtggtggtag cggctatgat
     9601 cattatttat tttctaccag ttattacaca agtatttcat caatattttg gttaagaata
     9661 cgagagtttg tgacaaaagt catgtcacaa acttttttct ttgtcatttt ttcgtaagaa
     9721 aaagcaaaat aaaagtatat acattgatta aaagtatata cttggatata atgtacttac
     9781 tatagaatga gaatggtata gagggtggcg aaatatgaaa aaaatgaaaa agtataaaat
     9841 tagaaaatct ggcaatagcg atgtaacaac tatcccacca gaagtaaaag aattcatggg
     9901 tgtgcagaca ggtgacgcaa tcagttatgt ttttcaatct gatggttctg tacgaatgat
     9961 caaagcacaa gaagaacctg atattgattc attagttgat tcgatcatga atcaatatga
    10021 agacgcgtta aaagatttgg ttgatttatg aggtatcttt cgactaaaga aattatcaaa
    10081 atcaacgcga aagttatttt acgtcactcg ccaggcgaaa tgatcggtgt aaaagatgca
    10141 aatgcattag atatggccgt caaacagcct tcacaagcag tattcaatca agaactctat
    10201 cctgaaatct atgaaaaagc ggcgatttta gcaattaatt tagctaaaaa acatcctttt
    10261 cataatggca ataaacgaac tgctcttgtt gccatgttgt tgtttcttca attgaataat
    10321 tgtccagttg ctttttctcg tcaagaagct gttgatttta tcataatgat taccactagt
    10381 tcattggatt tcgattcact aaagtccaag ataaccagtt atttacgaca aaccgcaata
    10441 aaatgaacga attaaaaact ttatttctca attagatcag catgtcatta aggaatat
//
LOCUS       DAFLWQ010000095        10318 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.098, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000095 DAFLWQ010000000
VERSION     DAFLWQ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10318
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.098"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(71..904)
                     /locus_tag="L1V16_002472"
     CDS             complement(71..904)
                     /locus_tag="L1V16_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBN1276764.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(1208..3373)
                     /locus_tag="L1V16_002473"
     CDS             complement(1208..3373)
                     /locus_tag="L1V16_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1276765.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            3633..5927
                     /locus_tag="L1V16_002474"
     CDS             3633..5927
                     /locus_tag="L1V16_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBN1276766.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            5920..6585
                     /gene="pgmB"
                     /locus_tag="L1V16_002475"
     CDS             5920..6585
                     /gene="pgmB"
                     /locus_tag="L1V16_002475"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBN1276767.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            6578..7585
                     /locus_tag="L1V16_002476"
     CDS             6578..7585
                     /locus_tag="L1V16_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBN1276768.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            7607..8626
                     /locus_tag="L1V16_002477"
     CDS             7607..8626
                     /locus_tag="L1V16_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1276769.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(8907..10274)
                     /gene="nhaC"
                     /locus_tag="L1V16_002478"
     CDS             complement(8907..10274)
                     /gene="nhaC"
                     /locus_tag="L1V16_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBN1276770.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
BASE COUNT         3198 a         2242 c         1909 g         2969 t
ORIGIN      
        1 ctctccaaac ggtataatcg tttggagagt tttattttaa tcagtttttt tatgttatat
       61 gttatatttt ttattcgttc acatctaatt cgatttccac cccgtagtga tcactgatga
      121 ttggactatc gatcccatca aaaatccgtt gatatttttt aacctgcatt ccttcaggga
      181 cgaaaataaa atctatacgc aatttttctg tattttgttc ccaaccatct attttctttt
      241 ccacagtagc tgcttttcct ttttcattcg cgacaacata cgaatcttga agaagaaggc
      301 aactttctct tacagtataa taaccttgag agtctactgg attattgaaa tcacctagga
      361 aaaaaagtgg tacgcgagtt tccaaaaagt agttttccaa gtttttccac tcaaaataaa
      421 agccactttt tttatctgtc caccaagaaa agtggcagct cgagacaaaa atgtcctgat
      481 catctatctt tgttttccca atcaagatct tgcgtgtctg ataatcttct ttcttttgaa
      541 attgggagac ggtaaggacc tgactttcca atgttttttt cgtaagcagt gcatttcctt
      601 cttcatattt atcataaccg atgtggctca tttcccaact ccaaaaatac tcttttccgt
      661 gttcctttaa aagctgaact aaacggtagg caaaattatc tttacggata ggtacttgat
      721 tctttaccgg acagaacttc attagcttcg caggttctac ttcttcagat tccagtaatt
      781 ggttgatttc ttgtaaagca atcacttcat aatcttctaa caggatctta tctgctaatt
      841 cttgcaattt tttctctggt tctggctcaa gccagctatg cgtgttgagt gtcatgaatt
      901 tcattggttt tctccttgtc ttcatttcga aacaaaaggg ttgtgacaaa atttttgtca
      961 caacctctcc agcaaatagt gttctcctgc taactcctca gtaataagct caatggacca
     1021 ggagctattt tttgtttggc tgtttttatc acttggtgca gggcagcttt ttcacgacct
     1081 ctccactaaa cagtattcaa actgctgctt ctcggtaata agcccaacca aacgaaaaat
     1141 aggaggagct atttttgttt ggctgttctt atgacttgat gcaggacagc tttttcacaa
     1201 cctctcctta cattttaatg gagccgatca ctttaccagc tgtcactgta cctaattgct
     1261 tgatcactac ttcttctact ttatcgtttg taaatacgat catgatcgtt ggatcttttt
     1321 cttcgttttg gatcacatca agatccatct cagctaattt cgttcctgtt cctacttctt
     1381 ggccttcttt gacagcaatc tcaaaagctg gctgattcat ttggactgta tcgattccca
     1441 tatggatcaa aacttcgata ccatctttcg tttccagccc aattgcatgt ttgctaggga
     1501 aaatacttgt cacttttcca gcgatcggcg caacaacttc tcttgatgtt ggaataacag
     1561 caaagccgtc acccatcatt ttttgtgaga ataccggatc ttttacttca gataaaggaa
     1621 tcacttctcc agaagctgcg gaaactagtt cttgttctat acctaagtat tgcttactac
     1681 ctgcttgtcc atttcctgta gaaaccattt ctggctctgg aatctctgct cctgattgca
     1741 gcagatcttc gatatctgat ttcaagacat ctgcttttgg tccataaact gcttggactc
     1801 cattgtcttt gacgatcaat cccatcgccc ctgctcgttt ccaggcttct tcagtcccta
     1861 ctttttctcg atcatttaca cttacgcgta accgagtcat acaagcatcg acatctttga
     1921 tattttcttt tcctcccagc aaatgaatga tctggaccac ttgctgatct gctgttcctg
     1981 ttccgctgtt agatacaacg gtttcttcac tgtcattgtc gtaatttccg ttacgtcccg
     2041 gtgtagcaaa gttgaatttt ttgatcaaga aatttgctaa gaaatacgta acaacaccaa
     2101 aagcgatcac acacaacacg aagttgataa gatctccacc tagacccgct ttgatagcta
     2161 acggtgtccg agtcagcaat tcgatattcc caaatgaatg gacccgcaat ggcaagatat
     2221 ctgccatcgc aaatgcagcc ccttggatca ctgaataaat gacatataat ggcacagcag
     2281 caaacataaa catgaactcc aatggttctg ttacacctgt tagaaagaca gccaacgctg
     2341 ctgaaaaata cattgattta tatcttgctt tcttatcagg atcgacatta cgatacatcg
     2401 caaaagccat tcccatcaag atacctgaag aaccaatcat ttgtcctact ttgaaacgag
     2461 ccggcgtcca gttatgcaac acaaactcat attgcgacat atcccctgca cctttaagat
     2521 tcactaaatc agtggcccaa gccaaccata acggatcttg cccaaatact tgtgtccccg
     2581 cctgtgcgcc tgataaaatc tcatacgatc cgccaagctg tgtatagttg ataggaatcg
     2641 tcagcatatg atgcaatcca aatggcaata gtaaacgttc taatgttcca aataaaaacg
     2701 gtgctagaat cggtgcgctt tcttgtgatt ctgcaatcca taaaccaaaa ttattgattc
     2761 cagcctgtac gtttggccac accacagcaa gaatcaatgc cacgattgtt gaccataaga
     2821 taacaacaaa cggaacaaag cgctttccat tgaaaaatga caaagcatcc ggcaattttc
     2881 tataattata gtacttatta taagccattg ccccgacaaa tccagcgatg atccctacga
     2941 atactcccat attcaaagct ggtgcttcca atacacttgt aaaaaatcct ttaaccatga
     3001 tcttcgtacc gaacagagtg tgggtaaatg catcttcatt cgcaagcatg tcacttgtga
     3061 caccaaagat agccccagtg atccgattga ttaaaataaa tgagatccca gctgcaaatg
     3121 ctccgcctgc tctttctttt gcccaacttc ctcctattgc taaagcaaat aaaatatgaa
     3181 gattaccaat aattgcccaa ccaatatttt caattactcc gcccgttgtg acaagcggcg
     3241 tccaatcagg attgatcaag ggaattgatt tccctatact gatcatcaac ccagctgccg
     3301 gcataactgc taccacaacc attaaagcct ttccaaattt ttgccaaaac tcaaaactaa
     3361 atatcttttt cattccgttt agctccttta cgcaatcggt ttcgttaaac gtattatagc
     3421 gtgcgttttc ttttttgtaa atgctttatt ttttattttt ctgtctatac cattctataa
     3481 aacctataat acgtgtgttc ccttctataa ttttctccta aaaatttatt tttttaagct
     3541 tttttctatg aaatattttc ttttgtctat tgacttgtgc aatcggttgc gtttattatg
     3601 aacgtataaa acagctcatt aggaggagaa aaatgaaaca gatcaaacga ctatttgcta
     3661 ttgatccatg gaaaatcagc acgacacaat tagataaaaa aaatcttcga ctgcaagaat
     3721 ctttaacaag tattggaaac ggttatatgg ggatgcgcgg gaactttgaa gaaacttact
     3781 caggggacca ccatcaaggt acttatttgg cgggtgtctg gtatcccgat aagacacgtg
     3841 tcggctggtg gaaaaatggt tatccagaat actttggaaa agtgatcaac gccttgaact
     3901 ttatcgcgat agatatttcg atcaacgatc agctgatcga cttggcttct ttggaaccag
     3961 aagactttta ctgggaatta gatatgaaaa atggtgtatt atctcgtaca ttcacaatca
     4021 ctacttctac taataaagta cgcatttcct tcgaacgttt tctgagcatt gtcaaaaaag
     4081 aatcagctta tatctattta actatagaaa tgcttgaagg tagcggaaca gtcaaactcg
     4141 tatcaaaatt ggatggaaat gttcaaaacg aagacagcaa ctatgatgaa catttttgga
     4201 atgagattga tcgtggaact atagaagaaa tcggctattt gacgactaaa actattccaa
     4261 acaactttgg gattgaacaa tttactgtta ctgcagcaat gcgccatttc gttaatggaa
     4321 aatcagtcat ccctgactat cacgaagata ctttagcatt acatggttgc ttgtctgcag
     4381 aattatctca aggtgagaca tggtcagtgg aaaaagaaat tatcgttctt actagtagag
     4441 atattccaga agcgcagcaa gcagaaaaag ctgtctcaga attaacgaac cagacaaaca
     4501 attatatcca agcaaaagaa gagcaaacag cggcttgggc agaacgatgg aagcttgccg
     4561 atgtggtcat cgaaggagac gaagaagcac aacaaggtat tcgattcaat ttgttccaac
     4621 tattctctac ttactacggc gaagatgaac gattgaatat cggccccaaa ggattcacag
     4681 gagaaaaata cggcggagcc acttactggg atacagaagc gtatgctgtc cctctttatc
     4741 ttgctttagc caaacctgaa gtaactaaga atctgctgaa atatcggcat aatcaactgc
     4801 cgcaagcaat ccacaacgct cagcaacaag gattaaaagg cgcgctttat cctatggtca
     4861 ccttcactgg tgtcgaatgc cataacgagt gggaaatcac attcgaggag attcaccgaa
     4921 atggcgcgat tgcctatgca atctacaatt atacgaatta caccggcgat acggaatatt
     4981 tgaaaaatga aggactggaa gttttagcag aaatcgcacg cttctgggca gaccgtgtcc
     5041 atttttcaaa acgagcaaat aaatacatga tccacggtgt gaccggccca aacgaatatg
     5101 agaacaatat caataacaat tggtatacaa atacgatcgc agcttgggtc ttgcgttaca
     5161 cgcgagaaaa ttatttaact tatcaaaaag aagctgctat cactatcagc gaagaagaac
     5221 tagccaaatg gaaagatatc gcagagaaca tgtacttccc agttgacgaa gaattaggaa
     5281 tctttgtcca gcatgacaca ttcttagata aagatctcat gcctgtatcc gatattccca
     5341 caagcgatct tcctctgaat cagcattggt cttgggacaa aatccttaga tcttgcttca
     5401 tcaagcaggc agatgtacta caggggattt atttcttcaa tgatactttt acaaaagaag
     5461 aaaagcaaaa aaactttgat ttctatgaac caatgactgt ccatgagtct tccctttcgc
     5521 caagtatcca ttcgatttta gcagcagaat taggaatgga aagcaaagct gtagaaatgt
     5581 accagcgaac agctcgcttg gatttggata attacaataa cgacacagaa gacggcttgc
     5641 acatcacttc catgactggt agctggttgt cgattgtcca aggatttgct caaatgaaaa
     5701 ctgcccatga tcagttgaga ttcgcaccat ttctgccaaa aacttggaaa gcttattctt
     5761 tccatatcaa ttatcgcgga cgtttattgt tcatctcagt cacagatgaa caagttactt
     5821 tcgagttatt agaaggttct cctctagaaa tttacgtcta tgaacagtct tattctttag
     5881 cggatcgtct agaaataacg ctaagaaagg aggaagcaaa tgtttaaagg ggtattgttt
     5941 gatttagacg gtgtcattac cgatactgct gaattccatt atcgtgcttg gcgaaagctt
     6001 ggtcaggaaa tcggcattac gatcgaccac acattcaacg aacagctaaa aggcgtcagc
     6061 cgagaagact cactctcttt gcttttagct tatggcggaa aagaacactc tttttcaaag
     6121 gaagaatttg cagaattagc gaaaagaaaa aacgattatt atttagagat gatccagacg
     6181 atcgaaccaa aagatgtctt ccccggggtc gtgcctttac tggattcttt aaaagaagaa
     6241 aaaatcaaga ttgctcttgc ttctgcaagt aaaaacgggc cattcctact tgaaaaaatg
     6301 ggtcttacac cttactttga tgctattgcc gacccggcag aagcaacaaa cggaaaacct
     6361 gcgccagata tcttcctcct tgcagcaaaa gctgtcggac taaaagcaga agaatgtatc
     6421 gggatcgaag acgcgcaagc cggtatccaa gccatcctct caagtggcgc tcaaccaatt
     6481 ggcgtgggac gtgctgaaga ccttggagag gagatcccgc ttgtccctga tacgactttt
     6541 cttacgatcg attacttgaa agaaaagtgg catgaccatg gataatccag agatctccgt
     6601 cgtaccagtt ccagagactg aaataaagaa aatcacattg aagaacgact acttagaagt
     6661 cgttcttctc aattacggtg cccgcctgca ccaaatcttc gcaccagaca aagaaggaaa
     6721 atcagaaaat gttttattgt cttacgatcg tttcgaagat gttctaacag acaaaagctt
     6781 ttttggagca actgtcggac ctgtagccgg aaggatccgg gatgcttctt ggggtgagca
     6841 tagattggag aaaaactgcg gatcacacca tatccacggt ggcacgaaag gctggtcttt
     6901 ccaattttgg gaagtagaag ttttcaaaac tccatcatca ataggtgtgg tcttttactt
     6961 aaaagatgaa ttttctacct atccaggacc aatcactgct acgatcactt accgtttaac
     7021 aaaaaacgaa ttagagatga caacctctgc tagtagcctt gttgaaacca tctgcaatcc
     7081 gaccaaccat gcctacttca acctttcagg aaatggaaca agagacatct atgaacatca
     7141 gttaacggtc tttttagatg gtgtgcttga attagatcaa gaaaaactgc ctactggaaa
     7201 ttggacaaaa aaagaaaaac tgccaatcga ctttagaaaa tccccaacac tgcaagagat
     7261 ccttgcatgt tatccagatg gactagatga tgtatttctt ttgcatcatc ctaggctttc
     7321 caaaacttcc ttacaattat tcgagaagca ttctggtcgc caaatgacta tagcaacttc
     7381 taataaaagt atggtattat tttctacgac tggattcgaa gctgatttct ctgtcaatgg
     7441 aaaacagatg cattcaaact acggattagc aatcgaaccg caagaaatcc ctgatatcgt
     7501 tcatttcccc aaatttggat cgatcaacct ccatcctggt caagaacgga tcagtcagac
     7561 gatttatcgg ttctctgcac aataacaaga gaaaggtgtt tttatcatgg ctattaccgt
     7621 aaaagatgtg gcgaaaaaag ccggtgttgc cacctcgacc gtctctcgtg tcatcaacga
     7681 tcatcctagt atttccgaga caacaaagaa gaaagtccga aaaattatgg atgaactagg
     7741 ttatgttcct aacatgactg cccgcaatct aggaaaacgc atttccagtg ccatcggcgt
     7801 aatcttaccc cctcttgatt caaaagagcg gatcggtaac ccattttatc ttgagatcat
     7861 ggaagcaatc aacgaagaag cgcggaatta tgatatgact acagcaatcg ctactgctaa
     7921 aaattttgaa ttgctgttag agaacgtcca gcgtatgcat ttacaaaaac aagtagatgg
     7981 ttttattcta gtgtattcag atagtcaaga tactgtcatt gattatttat accaaaacca
     8041 catccctttc actttgatcg gacagcctta tcatcatgag aacgaaatcg tttatgtaga
     8101 taatgataac cagcttctag gtaaacaagc aacagaattt ttgatccaga atggacataa
     8161 gaatatcctg tttgtgacaa acacgactca tgaaagtttg tatttcgaac gatatttcgg
     8221 ttatcaaaaa gcaatgatga tggctggtct tcctgcgtta tccagtgtag tactagagca
     8281 tccggaggat tatctgtcct ttgagaaaac gttgaaagaa aacgaagcca cagcattggt
     8341 ggtcattgac gatatcttcg cccttcgcac gatgcagttg gcgcaaatgt atggctatgt
     8401 cattccagag acactctccg tcattagctt caacaactcg atcttctcaa cattaacaca
     8461 cccttacctt acaagtatcg atatcgatat ctccgaatta ggacgtgtcg ctatgcaaaa
     8521 gctgcgcgaa ttgatccatg aagaattgag cagtggcgta cgtttggtca tccctcatcg
     8581 cttgatcaaa agagagacag tcgttccttt agaaaaccca tactaaatag ctgactcact
     8641 aaatacgctg accatttatc ctatggtcag ctttttatgt aaaagaagat actacttcta
     8701 acacattgtt tatctgtaaa aaagagcgtg ggacaaaagt aaagaacact tttgtctcac
     8761 gctctaaaca cgtataaacg gcggaagcag aagcaactcc ttcggaaata agctgaaatt
     8821 cacaaaaatt taaaaagcaa ttttcttgag tttcttctta tttcttggag ttaaacgctt
     8881 ctgtcccagc ctcttttttc cttccttcaa ttttttacac gtcgacgatt caataaaaaa
     8941 ccgcctaata ttgtaaagac aggtgcaaga atcgagaaaa aggcgaatgg caagtaatgc
     9001 aacgcgctaa ctttcatcgt tcccataatg aatgtgccgc tgactcccca cggtacgaga
     9061 gaattgacgg tcgcacctga atccgctagt gttcgtgtca aataggtttt tgataagcca
     9121 acgtcatcaa aagaacgctt gaatgtttct cctggaagaa tgatggacag atactgttct
     9181 ccaacgatca gattgattcc gatacagctc aaggcagtaa acccgactaa acgagaaggt
     9241 cggtccatct tttcttttaa ttcttgaacg atggtatcaa cgatcagata tttgatcagt
     9301 aacccaccta atgccaatgc aagtaaaatc aaactagcag aacctaacat actcatgatc
     9361 ccgcctcgag aaagcagttc atctagcttt ggatcaggtg tatttgcgac ataaccattc
     9421 atcaagatgt ctgctgcttt tccgaccgtc aaacttttct catggataaa agaaagaacg
     9481 agagcagctg tcgatcccgc tagtaatgta gggatagccg gaattttttt gattgccccc
     9541 ccaaataaaa taactagtgg aatcaatgtc caaggagaga tccaaaagct cgctttcatg
     9601 ttttggatca tttcattgat actagctaga tcggctgaat gactgttatg tcctaatatc
     9661 gtataaaaaa tcaacgaaag gacgaatgct gggaaatccg tataacgcat accagcgata
     9721 tgttcgaata gattaactcc tccaataccc gctgccaagt tggtcgtatc tgataaaggc
     9781 gagcagttat tccctaaaaa ggcaccggaa acgactgcgc ctgtagtcat tgcatcattg
     9841 aatccaagta aatgaccgat ccccaaaaaa gcaattccaa tcgtcgaaat cgttgtaaat
     9901 gaactgccga cagtcactcc gacaattgca caaacaagaa atgctgtcgg taaaaagaaa
     9961 cgcacagaaa caagtttaaa tccataaacc ataatcgtag ggatggttcc agataaaatc
    10021 catgaagcaa ctaagacacc aatcaaaaga aaaatcagga ttggaatgat ccctggagtg
    10081 attcctttga tgatcccgtc atggatctca tcccatgtga actttttaaa tctgccataa
    10141 aacaacaaac acatgaaagc tgcaaggatc gggatatgtg gcgagagctg gaatccgatg
    10201 atcagtactc ctaggagtgc caacaacacg atcaatacag cgatactttc ttttaaagaa
    10261 atatttttat tcatcgtcga tctcctattt caaatgaaaa ggccctgcca tgaaaaaa
//
LOCUS       DAFLWQ010000096        10311 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.099, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000096 DAFLWQ010000000
VERSION     DAFLWQ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.099"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..296
                     /locus_tag="L1V16_002479"
     CDS             <1..296
                     /locus_tag="L1V16_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1276771.1"
                     /translation="DCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRN
                     GLPKSMDFRKVNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            618..788
                     /locus_tag="L1V16_002480"
     CDS             618..788
                     /locus_tag="L1V16_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276772.1"
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEKV
                     DIADWLLQPREF"
     gene            802..1404
                     /locus_tag="L1V16_002481"
     CDS             802..1404
                     /locus_tag="L1V16_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1276773.1"
                     /translation="MAKIGYARVSSKEQNLDRQLKALEGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVVVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINNLVIELYKYQAESERKRIKERQAQGIEIAKKKGKFKGRQPKFKENDPRLQHAF
                     DLFLNGCSDKEVEEQTGINRRTFRRYRSRYNVTVDQRKKQ"
     gene            1420..2097
                     /locus_tag="L1V16_002482"
                     /pseudo
     CDS             1420..2097
                     /locus_tag="L1V16_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            2408..2572
                     /locus_tag="L1V16_002483"
                     /pseudo
     CDS             2408..2572
                     /locus_tag="L1V16_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000898188.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
     gene            2609..2905
                     /locus_tag="L1V16_002484"
     CDS             2609..2905
                     /locus_tag="L1V16_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HBN1276774.1"
                     /translation="MSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTNSASGVLRAN
                     EIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLKEKVVR"
     gene            2906..3322
                     /locus_tag="L1V16_002485"
     CDS             2906..3322
                     /locus_tag="L1V16_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HBN1276775.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            3342..4886
                     /locus_tag="L1V16_002486"
     CDS             3342..4886
                     /locus_tag="L1V16_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1276776.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            5029..5253
                     /locus_tag="L1V16_002487"
     CDS             5029..5253
                     /locus_tag="L1V16_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1276777.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            5268..6137
                     /locus_tag="L1V16_002488"
     CDS             5268..6137
                     /locus_tag="L1V16_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBN1276778.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            6118..6852
                     /locus_tag="L1V16_002489"
     CDS             6118..6852
                     /locus_tag="L1V16_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1276779.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            6885..7793
                     /locus_tag="L1V16_002490"
     CDS             6885..7793
                     /locus_tag="L1V16_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HBN1276780.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            7790..8332
                     /gene="sat4"
                     /locus_tag="L1V16_002491"
     CDS             7790..8332
                     /gene="sat4"
                     /locus_tag="L1V16_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HBN1276781.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            8425..9219
                     /locus_tag="L1V16_002492"
                     /note="aph(3')-IIIa"
     CDS             8425..9219
                     /locus_tag="L1V16_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HBN1276782.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            9495..10067
                     /locus_tag="L1V16_002493"
     CDS             9495..10067
                     /locus_tag="L1V16_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBN1276783.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPISLGFYEQNWYLIGFAG"
BASE COUNT         3624 a         1613 c         2249 g         2825 t
ORIGIN      
        1 ttgactgtgg aaaagaattt tctaactgga aagccattag taaccaacat gatattgata
       61 tatattttgc ggaccctgga acaccttctc aacgcccatt aaacgagaat tctaacggga
      121 ttctgcgtcg taatggactg ccgaaatcaa tggattttag aaaagtgaat cagacattta
      181 tttccagtgt cagcaatcaa cgtaatcata ttccaagaaa atcattgaat tacagaacac
      241 caatcgaaat atttttgagc tatgtacaag aagcatttta ttctagctta atttgacaaa
      301 tcatactatg atacgtgttt gtttttctgt gctgtttagt gaatgattag cagaaatata
      361 gagagtaaga ttttaattaa ttattagggg gagaaggaga gagtagcccg aaaactttta
      421 gttggcttgg actgaacgaa gtgagggaaa ggctactaaa acgtcgaggg gcagtgagag
      481 cgaagcgaac acttgatctt ttaagttgct atctttttaa ggtcaataga gtatacttat
      541 ttgtcctaat atggttttag cagtataatt gacttggtga ataggtcatt taagttgggc
      601 ataataggag gagtaaaatg aaaaaattta tttatcgagt tttagaaaat gacgaagtgg
      661 tggctatttt taatgagcaa caatatgcgc aagattttat cgcttacgaa aagacaattt
      721 ctgataagca atttgaaatt gaaaaagtag atatagctga ttggttattg caaccgagag
      781 aattttagag gttggttgaa aatggctaaa attggttatg cacgtgtcag tagcaaagaa
      841 cagaacttag atagacaact gaaagcgtta gagggcgttt ctaaggtctt ttcagacaaa
      901 ttaagcggtc aatcggtcga acgcccacaa ttacaagcta tgcttaacta tattcgtgaa
      961 ggggatatag ttgttgttac tgaattagat cgattaggac gaaataataa agaattaaca
     1021 gaattgatga atcaaattca aattaagggg gcaaccctgg aagtcttaaa tttaccctca
     1081 atgaatggta ttgaagatga aaatttaaga cggctgatta ataatttagt gattgaattg
     1141 tataagtacc aagcggaatc tgaacgcaaa cgaattaaag aacgccaagc ccaaggaatt
     1201 gaaattgcta agaaaaaagg aaaattcaaa gggcgacaac ctaaattcaa agaaaatgat
     1261 ccacgtttac aacacgcttt cgatttattt ttgaatggtt gttccgataa agaagttgaa
     1321 gaacaaactg gaattaatcg ccgaacgttt agaaggtatc gatcaagata caacgtgaca
     1381 gtagatcaaa gaaaaaaaca atgaaaagag ggatagttaa tgagtacggt tattttagct
     1441 gaaaaaccaa gccaggcatt agcctacgca agtgctttaa aacaaagcac caaaaaagac
     1501 ggttattttg agatcaaaga cccactattt acagatgaaa cgtttatcac ctttggtttt
     1561 gggcatttag tcgaattagc agaaccaggt cattataacg aaaagtggca gaactggaaa
     1621 cttgaatctt tgccgatttt tcctgatcga tacgattttg aagttgcaaa agataaggga
     1681 aagcagttta aaattgttgc tgaacttctc aaaaaggcaa atacaattat tgtcgcaaca
     1741 gatagcgaca gagaaggtga aaatatcgcc tggtcgatta tccataaagc aaatgccttt
     1801 tctaaagata aaacgtataa aagattatgg atcaatagct tagaaaaaga tgtgatccga
     1861 agcggttttc aaaatttgca accaggaatg aattactatc ccttttatca agaagcgcaa
     1921 acacgccaaa ttgccgattg gttgatcggc atgaacgcaa gccctttata taccttgaat
     1981 ttacaacaaa aaggcgtaca aggtacattt tcattaggac gtgtacaaac accgacttta
     2041 tatctcattt atcaacgcca ggaagcaata gaaaacttta aaaaagaacc ttttttcctg
     2101 aataattcat agttttacta atagtctttc ctaacattga tttaatagtc tttaaagtat
     2161 tctgcttcat cacccattag gtgatgaaaa aagaacccct ttctgattta gcggacaaat
     2221 actttgacct aatctcagaa gatataaaag aaaaaataat aaaatatccg atttatactt
     2281 tgtataaaga actaaagtag ttagcaaatc atttacagca aatcactatg ttccacatac
     2341 cattttacat acttacctta tccacgacac atgttgagat agtatcgaag ataaagaaag
     2401 ttgctccatg ttgtttttgc gagatgggga aatcaaagcc acattgacaa ccatgatgaa
     2461 taagcttgct ttcagtcata agctaatcct agaaccactt ttcaagtcag ttagccaaat
     2521 cgatgaagaa agcgaccgtg aaagaatgga cgctattgat aagctaatgg agcaactatt
     2581 ggaagaacgc aataccctta ttgcactgat gtccaaaggt ttcctagaac ctgctctttt
     2641 taatcaggaa cgaaatgttt tagatagtga gattaaaaat cttactaccg aaaaaacaaa
     2701 cctggtaacg aactctgcga gtggggtttt gcgagcaaac gagataaagg acctcattaa
     2761 ttatgtgtca gcagataatt ttaatggtga ctacacggaa gaactatttg aagaatttgt
     2821 agtgaacatc attgtaaatt ccagggatga gctgacattc aatttgaaat gcggtctttc
     2881 cctgaaagaa aaggtggtga gataaatggc atatattcca tatggataca aaattcaaga
     2941 tggagtggtt actgtcgatg aaaaggcagc aggtcaagta aaggtattct ttgagaaata
     3001 catatcagga ctatccctta cagtggctgg cgaacaggca ggtattgaaa agacacattc
     3061 tgtgatgggg cgcattttga aaaacgtcaa ctaccttgga aatgatacgt atccagcaat
     3121 tattgataaa gagatatttg ataaagctga agaagttaga gataaacgtg caaaggattt
     3181 aggacgagtg gtagagcttg ccgctttcac ctctccccct cccaaagaac gattcaaaat
     3241 gaaaaaggca gataataaga tgccagtgga tccttttgaa cgagcagaat acttatacag
     3301 tctgatagaa agcgaggaat aaagtgacag agaaaaatat aatggttatt cctgctcgta
     3361 aaagagtagg aagtacagcc gcaaaagaaa agataaagaa acttcgtgtt gctgcctatt
     3421 gccgtgtttc tacagaaaca gaagaacaaa attctagcta tgaggttcag gtctcacact
     3481 atacagagtt tataaagaaa aataatgaat gggagtttgc tggcatcttt gcagatgatg
     3541 gtatctctgg tacgaacact aaaaagcgtg acgaatttaa tcgcatgatt gcagagtgta
     3601 tggacggtaa catcgacatg gttattacaa aatccatcag ccgatttgcg cgtaacaccc
     3661 tagactgcct tcaatacatt agacagctca aggataagaa catatcagtt tattttgaga
     3721 aagagaacat caacaccacg gatgccaaag gtgaggtttt gctgactatt atggcatctt
     3781 tggcacagca ggaaagccag agcctttcac aaaacgttaa gcttgggcta cagtaccgat
     3841 accaacaagg aaaggtgcag gtcaaccata agcgatttat gggctacacg aaagatgaag
     3901 atggaaattt aactattgtc cccgaagaag ctgagattat caaacgcatc taccgagaat
     3961 accttgaggg tcagagtcta gtgggcattg gtcgagccct tgaaaaggat ggtattttaa
     4021 cagcagcggg aaaaccaaga tggcgaccag aatcagttaa gaagatactt caaaacgaaa
     4081 aatacatcgg agatgccctt ctgcaaaaga ctgtcacagt agattttctg accaagaaac
     4141 gagtgaaaaa tgaagggcat gttccccaat attatgttga aaatagccat gaagcgatta
     4201 ttcctaaaga gttatttttg caggcgcaag aagaaattca tcggagaagc aatatctaca
     4261 caggagaagg caagaacaaa agaatttaca gtagcaagta cgctttaagt gccatcacct
     4321 tctgtggaga ttgtggcgat atttatagac gggtctattg gaatatccac ggaagaaaag
     4381 aatttgtctg gcgatgcgtg actagaatcg agcaaggtcc tgaagtttgt aagaaccgaa
     4441 ccgtaaaaga agatgaactt tatggtgcag taatgactgc gattaataag ctacttgcag
     4501 gtgggaacaa tatgataaag acactggaag agaatattca tgctgtgatt ggcgaaacca
     4561 cagaatacca aatttcagag attaacaact cactagagga aaaacaaaaa gaactaatca
     4621 agctggcgaa caagggtcaa gactatgacc acttagcaga tgagattgat gagctgagag
     4681 acaagcgaca gatcctttta gtagaagatg cctccctcag tggcgagaac gagcgaatca
     4741 atgagctgat tgaatttatc cgcaagaaca aattccgcac cttagaatat gatgataagc
     4801 ttgtaaggaa gataatccag agcgttacag tctatgaagg ccacttcgtc atagccttca
     4861 aatctggcat cgaaatggaa atatgaaaac cagaagtaaa tagcccatga ctctacagta
     4921 gagttgtggg ttttcttttg cttgctgatt ataataatat tttaataact attgtgttta
     4981 tcaaccaaat ggtttataat attcttagcg taaacttgga ggtgctgtat gactacggca
     5041 gaaatgatta aagaactgtg tgagcaaatg aatataagtg tttccgaact tgctagacgt
     5101 attggccaga ctccacagaa tttcaataaa aaattacaac gagaaacagt aaccttggat
     5161 gagttgaagg ccattgctga tgtgctaggt gtcaagtttg tgcaggcatt tattttacca
     5221 gatggagaag aaataaaaat atctaacgaa taaaggagga tgtttatatg gtaggtaatg
     5281 ttattcaaat agtaacagag aaattatcat ctttgccttt tatagaaggc atcgtattag
     5341 ggggctcacg tgcaagaggc acccatacag aaaattctga tatagatatc ggaatctatt
     5401 acaattcaga ctcatttgac ctgacagcga ttaatcaaat tgctacagag ttggatgatg
     5461 agaatagaaa caaccttgtt gtacctcccg gagcgtgggg tgattgggtt aatggcggtg
     5521 gatggttagt tataaacggg tgtcatgttg acttgatatt acgtgatata aaacgggtgg
     5581 aacaaataat caaagatacg gagcaaggaa ttgttactgc caattatcag accgggcatc
     5641 cccatggtta tataagtgct atgtatcgtg gagaattagc gattagtaaa atactatatg
     5701 ctaagaacga aagcttatgc gaattaaaaa agcaggcaga aatttaccct actgctctaa
     5761 agaaaagctt gatgaacttt tttatatttg aagctgaatt ctctttaatg tttgtaaaag
     5821 caaatgcggg ggcagaggat aaatattata ttgcaggcca tgtttttcgt attatttcat
     5881 gcttaaatca agtactattt gcatgtaata atgcttattg cattaacgaa aagaaagcta
     5941 taaaactgct tgaaactttt gaatataaac ctgaaaaata tgccgaaaga gttaatcata
     6001 tttttgaagt actcggtctt tctctttttg aatgctacga catgaccgag aaactttata
     6061 aagaagtgaa tgaaattgta tcggagataa ataacttttt aaacgaggag agttcagatg
     6121 aaagaaaaca aatatgatga taatatattt tttcaaaaat acagtcaaat gagtcgctcg
     6181 cagaaaggac tggctggtgc gggagaatgg gagactttga aaaagatgct acctgatttt
     6241 aagggtaagc gtgtgcttga tttaggatgc ggctatggat ggcactgtat atatgcgatg
     6301 gaaaacggtg cttcctctgt agtaggtgtt gatatttctc ataaaatgct cgaagtagca
     6361 aaaggaaaaa cccattttcc acagattgaa tatgaatgct gtgccataga agatgtggat
     6421 ttcccagagg agagctttga tgtaatacta agttcgcttg cgtttcatta tgtagcagac
     6481 tatgagaatt taataaaaaa gatatatagg atgctgaagg ctggtggcaa tttagttttt
     6541 acagttgaac atcctgtttt tactgctcat ggaacacaag actggtatta taacgaaaaa
     6601 ggagaaatac tgcatttccc ggtggacaat tattattatg agggcaaacg gacagctatg
     6661 tttttggaag aaaaggttac aaaatatcat agaacactga ccacatatct aaatacactg
     6721 ctttcaaata gttttataat aaatcagatt gtggagccac agccgccaga gaacatgatg
     6781 gatattccgg ggatggcgga tgaaatgcga cgcccaatga tgctgattgt atcggcaaaa
     6841 aagaagatgt aataatatag aaaaaataaa cgaggagtat gtaaatgaga tcagaaaaag
     6901 aaatgatgga tttagtactt tctttagcag aacaggatga acgtattcga attgtgaccc
     6961 ttgaggggtc acgcgcaaat attaatatac ctaaagatga atttcaggat tatgatatta
     7021 catattttgt aagtgatata gaaccgttta tatctaatga tgactggctt aatcaatttg
     7081 ggaatataat aatgatgcaa aagccggagg atatggaatt attcccacct gaagaaaagg
     7141 gattttccta tcttatgcta tttgatgatt acaataaaat tgatcttacc ttattgccct
     7201 tggaagagtt agataattac ctaaagggcg ataaattaat aaaggttcta attgataaag
     7261 attgtagaat taaaagggac atagttccga ctgatataga ttatcatgta agaaagccaa
     7321 gcgcaaggga gtatgatgat tgctgcaatg aattttggaa tgtaacacct tatgttatta
     7381 aaggattgtg ccgtaaggaa attttatttg ctattgatca ttttaatcag attgttcgcc
     7441 atgagctgct gagaatgata tcatggaagg tcggcatcga aacaggcttt aaattaagtg
     7501 taggcaagaa ctataagttt attgaaaggt atatatccga ggatttgtgg gagaaacttt
     7561 tgtccaccta ccggatggat tcctatgaaa acatatggga agcattattt ctatgccatc
     7621 aattgttcag ggcggtatcc ggtgaggtgg cggaaaggct tcattatgcc tatccggagt
     7681 atgataggaa tataacaaaa tataccaggg acatgtataa aaaatacact ggtaaaaccg
     7741 gctgcctgga tagcacatat gccgctgata tagaagagag gcgggaacag tgattacaga
     7801 aatgaaagca gggcacctga aagatatcga taaacccagc gaaccatttg aggtgatagg
     7861 taagattata ccgaggtatg aaaacgagaa ttggaccttt acagaattac tctatgaagc
     7921 gccatattta aaaagctacc aagacgaaga ggatgaagag gatgaggagg cagattgcct
     7981 tgaatatatt gacaatactg ataagataat atatctttac taccaagacg ataaatgcgt
     8041 cggaaaagtt aaactgcgaa aaaattggaa ccggtacgct tatatagaag atatcgccgt
     8101 atgtaaggat ttcagggggc aaggcatagg cagcgcgctt atcaatatat ctatagaatg
     8161 ggcaaagcat aaaaacttgc atggactaat gcttgaaacc caggacaata accttatagc
     8221 ttgtaaattc tatcataatt gtggtttcaa aatcggctcc gtcgatacta tgttatacgc
     8281 caactttgaa aacaactttg aaaaagctgt tttctggtat ttaaggtttt agaatgcaag
     8341 gaacagtgaa ttggagttcg tcttgttata attagcttct tggggtatct ttaaatactg
     8401 tagaaaagag gaaggaaata ataaatggct aaaatgagaa tatcaccgga attgaaaaaa
     8461 ctgatcgaaa aataccgctg cgtaaaagat acggaaggaa tgtctcctgc taaggtatat
     8521 aagctggtgg gagaaaatga aaacctatat ttaaaaatga cggacagccg gtataaaggg
     8581 accacctatg atgtggaacg ggaaaaggac atgatgctat ggctggaagg aaagctgcct
     8641 gttccaaagg tcctgcactt tgaacggcat gatggctgga gcaatctgct catgagtgag
     8701 gccgatggcg tcctttgctc ggaagagtat gaagatgaac aaagccctga aaagattatc
     8761 gagctgtatg cggagtgcat caggctcttt cactccatcg acatatcgga ttgtccctat
     8821 acgaatagct tagacagccg cttagccgaa ttggattact tactgaataa cgatctggcc
     8881 gatgtggatt gcgaaaactg ggaagaagac actccattta aagatccgcg cgagctgtat
     8941 gattttttaa agacggaaaa gcccgaagag gaacttgtct tttcccacgg cgacctggga
     9001 gacagcaaca tctttgtgaa agatggcaaa gtaagtggct ttattgatct tgggagaagc
     9061 ggcagggcgg acaagtggta tgacattgcc ttctgcgtcc ggtcgatcag ggaggatatc
     9121 ggggaagaac agtatgtcga gctatttttt gacttactgg ggatcaagcc tgattgggag
     9181 aaaataaaat attatatttt actggatgaa ttgttttagt acctagattt agatgtctaa
     9241 aaagctttaa ctacaagctt tttagacatc taatcttttc tgaagtacat ccgcaactgt
     9301 ccatactctg atgttttata tcttttctaa aagttcgcta gatagagttc tatattagag
     9361 atgtaaagag ttttggtgaa gaggtttgtg agtatggctt ttataaccag ggtgcaatga
     9421 gaagcactaa cagcagctag cttaagaacg cataggatat actttttatg gaagtcacag
     9481 aggaggaata aaatttgaac aggattaaca gagtaacctc tattcttatt cagctgcaat
     9541 caaaaaaaat aattcctgcc aaagaaattg cacagcgatt taatataagc ttaaggacag
     9601 tttacagaga tatccggaca cttgaagaag ccggaatacc aattggatct gaggccggaa
     9661 aaggatattt tcttgtagag ggcttcctac ttccgccggt aatgtttaca gcggcggaag
     9721 tgggtgcatt gattacagca gggaaatttt taaattgcca tggagatgaa tcatttataa
     9781 aggattttga ttcagctatg tataaaatca aatctatttt gaagcatggt gaaaaaaact
     9841 atgcacagga gttggagaac agtattaacg tgtacagcac atctggacag aaaaatacat
     9901 tggcggataa cgttattgca gcaattcaga ctgcaatctg caataaaagg gtaatatcaa
     9961 ttcaatatcc tgcatcagga gggcaagaac cggaaagcag aatgatagag cctatatcac
    10021 tggggtttta tgaacagaac tggtacttaa tcggttttgc aggctaagaa atgaatatag
    10081 gaattttcgt gtggatcgga ttaaaagcat ttgcatagaa gaagagctct gtcaaagcca
    10141 tgatggctct ttggaacaaa tattaaaaca aatgctttca tataaaaaac tatatgccct
    10201 acaatgccgt tgtaaaaatt ggggaaaagg gatatattga ttttatatct ttctcaaaat
    10261 aaatataaaa gccctttaaa gagggctttt atatattaat cacaaatcac t
//
LOCUS       DAFLWQ010000097        10260 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.100, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000097 DAFLWQ010000000
VERSION     DAFLWQ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10260
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.100"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..448
                     /locus_tag="L1V16_002494"
     CDS             <1..448
                     /locus_tag="L1V16_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBN1276784.1"
                     /translation="FVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTTLFVSVIYFA
                     LLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGLLPKFMKVAD
                     LDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            457..684
                     /locus_tag="L1V16_002495"
     CDS             457..684
                     /locus_tag="L1V16_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1276785.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            1320..1691
                     /locus_tag="L1V16_002496"
     CDS             1320..1691
                     /locus_tag="L1V16_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276786.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(1947..2189)
                     /locus_tag="L1V16_002497"
     CDS             complement(1947..2189)
                     /locus_tag="L1V16_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBN1276787.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(2221..3123)
                     /locus_tag="L1V16_002498"
     CDS             complement(2221..3123)
                     /locus_tag="L1V16_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBN1276788.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(3136..3324)
                     /locus_tag="L1V16_002499"
     CDS             complement(3136..3324)
                     /locus_tag="L1V16_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBN1276789.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(3338..3901)
                     /gene="amaP"
                     /locus_tag="L1V16_002500"
     CDS             complement(3338..3901)
                     /gene="amaP"
                     /locus_tag="L1V16_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBN1276790.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(3939..4832)
                     /locus_tag="L1V16_002501"
     CDS             complement(3939..4832)
                     /locus_tag="L1V16_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1276791.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(4910..5833)
                     /locus_tag="L1V16_002502"
     CDS             complement(4910..5833)
                     /locus_tag="L1V16_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBN1276792.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(5882..6232)
                     /locus_tag="L1V16_002503"
     CDS             complement(5882..6232)
                     /locus_tag="L1V16_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBN1276793.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(6265..7167)
                     /locus_tag="L1V16_002504"
     CDS             complement(6265..7167)
                     /locus_tag="L1V16_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBN1276794.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(7160..8017)
                     /locus_tag="L1V16_002505"
     CDS             complement(7160..8017)
                     /locus_tag="L1V16_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBN1276795.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            8351..9160
                     /locus_tag="L1V16_002506"
     CDS             8351..9160
                     /locus_tag="L1V16_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1276796.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            9200..9697
                     /locus_tag="L1V16_002507"
     CDS             9200..9697
                     /locus_tag="L1V16_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBN1276797.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(10082..10155)
                     /locus_tag="L1V16_002508"
     tRNA            complement(10082..10155)
                     /locus_tag="L1V16_002508"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10119..10121),aa:Ile,seq:cat)
BASE COUNT         2961 a         1948 c         1761 g         3590 t
ORIGIN      
        1 atttgtcgtt ttaggtataa gtgccgtatt tattttgttc ggcgtacttt tttatactca
       61 gatcgctaca agcgaaaaag gattcaattt tgattggcag accacattat ttgtttctgt
      121 catttacttt gcccttctcc tagggatcgt tattgcttat ttcttattga aactattgaa
      181 aaaaatcgaa gataaccaag ctttttccac tcaaagctta aacatactaa aaaaaatcga
      241 acgaaccatt ttgtttattg gtttcgcctt ttttggctta cttcctaaat ttatgaaagt
      301 agcggattta gacgatgctc caggtttgat gttggtagga atcgctgtcg tattcattcc
      361 ttttgcagta tacacattaa caagcgtgct ggaaaaactg cttgaacatg cgattttact
      421 taagacagat catgatttga cagtgtgagg tgcgacatgg caattatcgt taatttagat
      481 gtagtattag ctcaaaaaaa aatgagtgtg actgaattga gtgagaaagt gggcattacg
      541 atggcaaaca tctctattct aaaaaatgga aaagcaaaag ccatccgttt ttccactctc
      601 gaaaaaatct gccaagtttt ggagtgtcaa ccaggtgatt tgttgaccta taaaaatgac
      661 tcgaatacta taccagaaga ataaaataaa gtagaacaaa cagtaaataa aaaataatct
      721 gaatgataga tgtgtgagac ttttagaagt tatttacgtc tattattcag attttttatt
      781 tcgattgaat accgttttat ctataaataa gatatgtact gactcataca aagggggcct
      841 tttcttctcc atgtactatc acttttcctg atacaactgg tttcctgtta cgttgtagtt
      901 ggatctgctt ttagtataat actttattca ttccaccaga ctgatagcag tttgagcagt
      961 ctaaataatc atgtagtatt acaggccatt ctgtttcata ccttgaagtg cttaaaactt
     1021 cagctaatgg cccattgtgt taactcttac tccattcttt tttagtaagc tcccatatat
     1081 actgtaaagc cttctatata ttatgtcatg ttgcttttta acatttacta tgtagttttg
     1141 ataaaatgat ttgaataaca gtgatggaca attctttttt atttttaaca ttattttgat
     1201 aataatgatt atttatttaa aaatacatta gataacattt gttacgacac gaaaaagctt
     1261 cacaaacaaa tatcgttatt ttaaaatgag ggcgaactca cacaattagg aggaatagta
     1321 tgccatttat tgtttacttt tttctttcat tactcgtgat ctatattcca ttaccaacat
     1381 ttttcctgct cgtcaatcgt ctagcagagc aacatgatac gattgctgct cttacgaaac
     1441 tttgtttact tctatttgtt tgtctagatt actttacgag ctattattgg ctaaaacaga
     1501 caagagtaaa aaagagatat tatttcttcc ttgtcttttt caatctcttt gagtttctga
     1561 tccattgctt tttacttcat cagtatcata cgatccattt gtggatcatc tgggttttca
     1621 aagtggtcgt attattttgt atgttcacct ttcctatctc aagaaaattt agggaggcat
     1681 tgttttatta aagaagcttc tctgtatcaa taaagacaca tttaaggaaa aacttttaaa
     1741 aatctaattg ggaatttgcc cgcataaata agaggctgtg acaaaagtct tgtcacagcc
     1801 tcttattccg tataaacagt gttcaaaagc ttgcatcttc gataatatgc ccaaccaaat
     1861 gaaaaatatg agaagctatt tttgtttggc tgttcttatt acttgatgaa gaacagcttt
     1921 ttcacgacct ctttttaaaa gtctttttac agttttcgag caaagaatga tacgattagt
     1981 actaaaatga tggcaccaat caatgatggc acgattgcca ttcctgcaat acttggtccc
     2041 caagaaccta ataatgcttg accaagtgct gatccaacta aacctgctac gacatttgca
     2101 ataatcccca tcgaagaacc tttattcgtg attgctcctg caattgctcc gataattcct
     2161 ccgacgataa gtgaccaaat aaatcccatg tttcgttcct cctaatgttt tacttcctta
     2221 ttactgaacc cgtggttctg tattttcttt tactttttgt gcgccgcttc cagctgctga
     2281 ttttacttta tctgtttgat tcgaagcaaa ttcaccggtt tttttcgctg cgtcagttac
     2341 tttgtcttgc accgtttctt gatctttttc aaattcttct tttgttttga tgtccactac
     2401 gttagcgttg acttcgatca cttctaaatg tgtcatattt tttacttctt tgccgattac
     2461 ttcttgcatt tcttcaaaga ttttttcgat atctttgcca tattccacaa tgacatccat
     2521 atcaactgct acttgttttt taccgacttc tgtttcgatc ccagccgtta cattatctgt
     2581 attcacaagt tttcctgcca cattagagaa gaaaccaccg tttgcagata ataaaccgtc
     2641 tacttgttca attgcgattc cgatgatttt ttgcacaact ttatcttcat aattcagctc
     2701 accgcgcatt gaatcttcct gttcagaatc atgctttcct tggttatttg tatgatcaga
     2761 accaagtttt ccttgtccgt ttgtgtggtc agaactaagt ttttcttgtg ctttcgcatg
     2821 gtcagaagga tgtttttgct cttccacagg tttagaagga tcgattgcat catgttgttc
     2881 tggaacttta gattctggag ttcctggatg atgaggtgca tgcttttctg catcatgttt
     2941 cttctcttct actccttgtt gaacgttagg gactactgga tctggatgtg cagatactgg
     3001 tgctgttttg ttcttttcat cgttcacacc atttgattgg tttggtgtcg ttgggtctgg
     3061 atgtgcagac actggttttt ggttgttcat tttattgtta ttatttttgt tattgttatt
     3121 catggatgtt tcctcctaag atttaaaata gtgatctaag attttcgttt gtttcagata
     3181 aaaaccgata gcgacgccga tcgctgccat gatcaagatc aataaggtct tgaaaaagcc
     3241 cacggtgatc cataaaacgg ctaatatcaa tccaagtacc ccaaagatga tagggagctt
     3301 gtatgtcgaa aatagttctt tcatttttgg tcccccccta ttctactcgt ttgcggtcat
     3361 tgcttcgttt agctggttct tcaaagcctg tgtatttcac cgatactttc actggctctt
     3421 ttgttcccaa tatgtgttgt acttcatttt cgatttcttt catcaatgtt cctgttttac
     3481 caatgagtgc tgaagttcgt ttcaactccc cttttacatt gacggcgatc ttgtttttcg
     3541 ttgctttgac atttactttt ggtgaatgga tgaattcatc ttcatgcaag tgagaacgaa
     3601 ccattccttc aattgctttt ttatccaacg tcaactcccc atcaccatgt ttcagtagaa
     3661 agtttccgat tgtttttgga taaaacagga aaacaagtaa cgtgataatt gtcaaaatag
     3721 caaatgcaac ggcaagccaa aatacatatt gttgcacgta tgaattagtg atggaaaaga
     3781 atcgaaactt ctctagctga aaaggcaatg gataggttgc acttaatagt atcgcaaaca
     3841 aaagcacaga tagcaaaagt aatgttccga tcactccgat cgtttttaca cctttattca
     3901 ttttcgcacc tcctcatagg ggtgaaacga tcaacttctt ataagttgat cgcttctcca
     3961 ccagttactc cgtaaatttg ggctgtaaca taacttgctt tattcgatgc taagaaaaca
     4021 taaactggtg ctaattctcc tggctgacct gcacgttcta gtaaactttg ctgaccaaat
     4081 tcagggatcg aatcagaagg ttgtccttcg tctagttgta atggtgtcca gattggacca
     4141 ggtgctacac catttacacg gattccttta ggtgcaagct gttttgctaa accgatcgta
     4201 aagttagcga ttgaagcttt tgttgctgcg taatctaata aatgttcgct tggattgaat
     4261 gcttgaacag aagttgttgt tacgattgct cctcctgctg ggatatgcgg aacagcttct
     4321 ttcactaaag caaacatagc gatgatgttt atcataaatg tgtctttgac ttgctcaagt
     4381 ggtaactcag caatagactg acaagaaatt tgctgtcctg cgtttagtac catcgtatct
     4441 agcccgccaa gttcactcac ggctttatct atgatttctt taggtgcttg ttcgtcacga
     4501 agatcaaaag gtagtaagac aatcttacgt cctgcaactt tcacgtattt tgctacttcc
     4561 tctgcatctt tttcttctcc tgggaagaat tgaagagcga tatctgcccc ttctctagca
     4621 aatgcaatcg ctgctgcacg accgatccct gaatctccac cagtgattag tacacggcgg
     4681 ttttctagtt gattattgcc ttcataggat tcttctccac aatcaggaac aggaatcata
     4741 ttctgctgta aagctggtgt atcctgatct tgtttaggaa atttctccgt atggtacaag
     4801 tttcgcgggt cgattaattt tggttctgtc attgctgtat tcctcctagt ttttaaattg
     4861 tattgccaaa acaaatttct ttgtttgata cctgttttaa atagattctt taatttgtat
     4921 aatctttccg gtataaatgg taacctaaaa ctactgctgc tatcaaagag ccaaagacta
     4981 cgagtataaa gcctagagca gaacttttac ccggtaatcc tcctgtattc attccccaaa
     5041 tccctgcgaa caacgccgga acggaaatga ttaatgcagc tgaatctaga tatttcatga
     5101 tatgatttag attattgtcc atcatcccgt tgaatagatc accaatactc tctaataaat
     5161 ctcgatagat ctcgatcatt ttttctgttt gtcgctgtct caaatggaca tcatagagta
     5221 gctgttcatc gtctaaacgt ttgatgaaag tttcagaatt ccataattga tccattgttt
     5281 cccgttgatc tcttaaggta tgatcgatat atacgatgtc tctttcaaga tctgcctgtt
     5341 tatacagttc ttcattttcc gttgttttac gagctgcttt atccaaagcg tcaattcgct
     5401 ttttcatctc tcttagttct ttcacgtaat gggtgtaaat atctaataat gtatacgtga
     5461 tgatcttttc aaacgagttt aaatgatttc catgctttgt cagcagccga tccacaaatt
     5521 cggtttttct atcgatacaa gtaatcaaga gattatcgga aagtacaaaa gatattggcg
     5581 ttaatttttt ttcgatacga ttatctgact gatctagatt aatcactacc aaagaaaatg
     5641 gatgctctag tttcgtctca taaaggcgct ccatccgaga aacttcttcc ggatattcgg
     5701 ttcctacgaa aatatcatca ggaagctcga attcttcgat tgcttgctca atctcttcgg
     5761 gctttgcact atcaagtacg agccaattat attttttttc atctgtttct attacattct
     5821 tttcttcatc cacaaagtag tatctcaatg tatacctcct ttttggactt tctcgaaact
     5881 attagctgaa gaagcagttc tttaatttga tattataatc gagtactgcg atttcatttt
     5941 ctaatgaaaa gctgtcaagc tgtttgttga agtccatgtt caatcgttta ccgaaataat
     6001 tttgctctaa tttagatgta tagatgtcca ataatggatg ctcgatttta gtcgcatatt
     6061 ctccaaattc cgaaacaaaa ggaatgattt gaaaaaagct gccttttgca aaagcacctt
     6121 tgtcccttag aaatggatcg gaatcattga taagcgcgag tgcgattttt gtattttccc
     6181 caaccttttc aattaacgtc tctactgcat ttttagacat tgtaatttcc attcctactc
     6241 cccctcttca gttgttgtct tctattattt aacaactaca tctgtttttg gttgaacttt
     6301 tgcatatttt ggatatttag ggaatttagc tacacaacgg aaagccgtca tccctgcata
     6361 tttttcgtaa tatttcttcg ttggcccttc aaaatccttg ctccacggtt tcacatgtcc
     6421 tgaaaaatgg ataatgtaag gattgttgcg agtttcttcg tattcacgtt cacctgctgc
     6481 tgttggatgt ttttttgctt ttgccatgat atagccttgt gcattccaac gcggatgaag
     6541 tggtaaccaa cggtcatgta agatagcatt taatgcatct tggtcatgga atcgtaattt
     6601 ttctggatta tgttcgatga aatctaatac tttttgcgta atattttcat ctaaccattt
     6661 tttcacattg atcagcatca aacctgagtt gaaataacgc attgatttag ctgaaatttt
     6721 cattttttcc agtcgttgat ggaacccagc gtcttcaaca gctgctacga ttgaatcacc
     6781 gaagtcaaga cgccataatt tagagatatc ttgtaaagcg atcatgtcgc aatccatata
     6841 taagatacgt tcaacttctg tgccgcggaa caattccgga atcgcaatac gataataagc
     6901 tgtttctgga atacgatcgc tgattaccac atttgtaaag aattctttat tgattttcaa
     6961 gaattccaca tctgagttca ttcgtgcgtt tttcactgag aagcgtaaaa gctgtttact
     7021 ttcaaaatcg atatcatcgt caatcacata gaaccgaaca aatttagacg ggttgcaatt
     7081 atctaatact gagacaaata atgcagctaa atgtggtacg aattttgtgt tacaacttgc
     7141 gactactgct atttcttttt tattcattga tctcgcctac tttcgttaga gtactgtgtg
     7201 ctaatttttt taagtataaa ttggtatacg gatgatcttt caacgtattc caaggtttat
     7261 catgtcctgt aaagtgaacg atcgaaggtt tttcatttcc ttctttatac tgacgttcat
     7321 atttttcatt tggtgctgga tgacgttcaa aaatcagcga agtctgcatg ttccattttg
     7381 gatgaagttg ttcccaatct tcataaagta cagcattcaa agcatcttgg tcgtgataga
     7441 tgattcgatc gccattttca ctgaggtaat ggatagtttt ttctgtaatt tcttttttat
     7501 tccattgatc aatgtcaatc accatcactc ctgaattgaa gtacaagtca tcggaatcga
     7561 ttcctaatct ttccaaagct ttcacttggc ctggatcgat aatagcgccg attgtttttc
     7621 catttaacgg ctcatcatat agttttacga tatcgtctag tactaacaca tctgaatcta
     7681 agtaaaggac tttcttataa tcctctttag ctaataagtt tggtaaagaa attcttaagt
     7741 aagcggtagt tgtgatatgg tcactgacta ggaagtcttc gtagatatct ttttccactg
     7801 tcaggaattg gatacttgca ttacttgaat atttatttac cgtttcttcc aatccttctt
     7861 tactatattc tgatagacca tcgtcaatca cataaaattt tatgcgtctt gttttattgc
     7921 aattttctaa tgcagttgcg atcatcacgc tcaagtaagg agcataattt tcgtctgaag
     7981 cagttaccac aggaactacg ccgtatctct tctccatcaa aatcactcct ttttctaatc
     8041 tttttctaac ctgttctaca tctagaatat tcctcatttg gttttaaagc aaaatatatg
     8101 ctttgttttc attgaatatt ttaaaatttt tttatcacaa aacgcatcgg taagcgctaa
     8161 ctattcgttt ttcatggctt tttattcaaa ggtattgacc aaaaactact atatatagcc
     8221 acctttttct taagaatgtt ttttgaaaaa attcataatg acaaagcaag ttagtttcat
     8281 ttttttaaat tctcatttaa tcttaaggta acaggaaaat agatatgtaa aaagaaagta
     8341 ggaagataaa atgaaactag cagcgattga tttagacggt accttgcttg atcgaaatgg
     8401 aaagatacca gaagaaaata tccaagcact tcggaaattt gatgaaaatg gcggaatcgt
     8461 aaccgtcgct accggaagga acagcatttc tgctaaagat attttttccg aattaggaat
     8521 cggtggctat ttgatttctt ccaatggttc actgattgct gaaatgaagg atggaaaaat
     8581 ggcgaaagtt ctcagacgtt caaaaataga tagcgataca ctgagaaaag ccttcttcta
     8641 tgctcaagaa gcgaaaatat ccatcattgc tagccgagaa acccaagatg atcagctgac
     8701 attcgatgaa tcaaatctag tcaaagatga cccttattat gaacatttca atttacagaa
     8761 ccattctttt gatcaaattt taaatatgtt ggaagatcct tctcttagct atcttaaatt
     8821 agcattaaca gataagagtg aagaaaaact acagaagcta caaagagatc tgcaagcaga
     8881 tggtatccaa tcagtattct ctgatccgca tttcttagaa atcacgccta caggtatcac
     8941 taaagctcat tcacttgttt ttctggcgga ttaccttgga atcgaatcga gtgacatcat
     9001 ggcttttggc gatcaagaaa acgacattgc tatgttgaat tacagcgggt tgagtattgc
     9061 gatggggaat gcacagcgac aagtaaaaga aattgcaaac caagtaacac tgacgaatga
     9121 agaagctggt gttgcttata ttttaaaaaa cttctattaa aaagaataaa atgacgatat
     9181 gaatgtagga ggaaagaaaa tgttagttat tattgatatg caaaatcata ttcttgatcc
     9241 aaacagcgaa ttttatattc cagagtcaga tcaattggca gaacgtattg ctcaaagatt
     9301 agctaaagca cgccaaaata atgaatatat tctcttcaca cgggatatac cagttgaact
     9361 gaaggacaaa gaagaagaac gagaagattt gcaattgatc cctcttcttt ctccacaaga
     9421 aaatgaacga gtgattaaaa agtattactt tacgattcca cctgaaactt tagctgaaat
     9481 ccaggaaact ttatttgaaa gcaaagaaga acaaaaagag atcgaagtag tcgggattga
     9541 aacaaacttg tgtgtactct ctaatctgat aggcctgcag agtgcttttc ctgaagcaga
     9601 cttttttgtt gatccaatgt tagtctccag tagaaaacac ggagaatccg ctttagagct
     9661 gttgaaagat ttcaacgtct ctatcgtcga atcataaaaa tatctatctt catttacgat
     9721 atttaacaca caataaaaaa agcacgcaga actgttttag tcctacgtgc tttttctatc
     9781 aaagtagatt ggctttttta tgacacagag tgaaacggca ggctcacgac ctctttctta
     9841 aatggtgttc aatcagctga ccctcggtat tagcttaaca aacggcaaaa tatgaggaac
     9901 tatttttccg tttgttaagc taatactcag gtcaaaacgc tgatttcaca acctcttcct
     9961 taaacggtat tcaaaagctt gcatctgcag taataagaac agccaagtaa aaacataaga
    10021 agctgttttt acttggctgt tcttattact tgatgcaggg cagctttttc acaacctctt
    10081 atgtaccttg taggactcga acctacgacc ggacggttat gagccgtctg ctctaaccaa
    10141 ctgagctaaa ggtacatcat aaataaaatt tatttttgtt acttttcaac tatagcacga
    10201 atgacaaact ctcacaagtt tcaaaatata agtaaaataa tattgttatt cttatttctt
//
LOCUS       DAFLWQ010000098         9919 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.101, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000098 DAFLWQ010000000
VERSION     DAFLWQ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9919
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.101"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(67..312)
                     /locus_tag="L1V16_002509"
     CDS             complement(67..312)
                     /locus_tag="L1V16_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBN1276798.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(427..1005)
                     /locus_tag="L1V16_002510"
     CDS             complement(427..1005)
                     /locus_tag="L1V16_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1276799.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(1082..1612)
                     /locus_tag="L1V16_002511"
     CDS             complement(1082..1612)
                     /locus_tag="L1V16_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBN1276800.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1616..2476)
                     /gene="rlmB"
                     /locus_tag="L1V16_002512"
     CDS             complement(1616..2476)
                     /gene="rlmB"
                     /locus_tag="L1V16_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBN1276801.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2469..2864)
                     /locus_tag="L1V16_002513"
     CDS             complement(2469..2864)
                     /locus_tag="L1V16_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBN1276802.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2861..4273)
                     /locus_tag="L1V16_002514"
     CDS             complement(2861..4273)
                     /locus_tag="L1V16_002514"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBN1276803.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(4270..4806)
                     /gene="cysE"
                     /locus_tag="L1V16_002515"
     CDS             complement(4270..4806)
                     /gene="cysE"
                     /locus_tag="L1V16_002515"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBN1276804.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(4892..5131)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(5128..6588)
                     /locus_tag="L1V16_002516"
     CDS             complement(5128..6588)
                     /locus_tag="L1V16_002516"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBN1276805.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6758..7915)
                     /locus_tag="L1V16_002517"
     CDS             complement(6758..7915)
                     /locus_tag="L1V16_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBN1276806.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7949..9319)
                     /gene="radA"
                     /locus_tag="L1V16_002518"
     CDS             complement(7949..9319)
                     /gene="radA"
                     /locus_tag="L1V16_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBN1276807.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(9382..9909)
                     /locus_tag="L1V16_002519"
     CDS             complement(9382..9909)
                     /locus_tag="L1V16_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBN1276808.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         2522 a         2225 c         1791 g         3381 t
ORIGIN      
        1 atttgatttt gtacaaccca tcagtcctta ttgacaaaga gcccgaatct caggctcgtt
       61 tgctttttaa actgcttcag ttaaaaattc gatctcaact gtccgagtaa gtacatctga
      121 atagctgtaa gatactcgtt caaaagaatt ttcttcagga tccaaatcaa caacgaatac
      181 tgaaggatag gtttctgtta aaacgccgcg gcgttctgtt tgacgctttc ttcctgtctg
      241 agcaaccaac atgattgggc tgccgatacg accttctaaa tctttcttga ttgaagctaa
      301 agttgttggc atacagttca cctctactat caactatacc acatattttt aaaattttca
      361 agtttaccat aaaaaaaaaa gaaatgcaat aaaaataaat aagaagctca ttaagatttt
      421 tctaaattat tcctcattat aaaatttcaa gtgttttttt attttgagtt ttactctccc
      481 gtaagcgctc attacttgct tgtgatccat tgctaaacat tcagccatgt ctacaaaatc
      541 aacgccttgc atataataat gaaaaatttt agcttctatt tttgaaaact ggatttcgca
      601 attttcgatt gcttctttta ataaaagatg ctgaatcgct aaaggttctt gcaatgtgat
      661 ctctgctaaa aagtctggtc cttctgtctc tattttttgg tcgattgaga cttcatcttt
      721 ttgatcacga cgcttcagcg cgttctgctt cctcaacaga gaatagattt gattgcttat
      781 aatgctttta taataacttc caaagctaac acctttgctt ttttcgtaag ttctcaatgc
      841 ctgatataaa gcgatccttg cttcttgttc ccaatcctca gaaacataat ttcttaaata
      901 ataggtgttt ttcaaacgta gtaaaagtgg aaaatatttt tgatacaggg cagcaaatgc
      961 ttcttcgtca ccattacgtg cagcgcgcaa taactcctca gacataaaat aattcctcca
     1021 taaattcgtt tatggaggaa tcttatcatc aatgattcat cgaactgatt agaacgatat
     1081 gttatttatt ttttctcatt aaatcgtcca atttttggga caattttttt aactgctctt
     1141 cattccatgg agaattacgt cggaaatcaa taaaatgcat atctttattt tcttgggcta
     1201 ttgttttttc cgtttttttt atcgtcttat ataattcata agcagaagtt cgtaatgctc
     1261 cttgggaaaa gatcatccac tgttctgcta aatcgcttgt cgccactgtc acttgtgtca
     1321 aacggtcatt cagctgacca gcgattctct cgatataact gtcagccgtt tcgtcttctt
     1381 tcgtaaaaac aacatccaac tggtatttct tataattttg ttggatgccc ggaactagtt
     1441 gggcatcgaa gacaacgatg acttccattc cttcatattt cgcataattt gataaacgat
     1501 gtaaaagagc ttctcttgca tccgccattt tgtcctgctt tttaagctgg acaagttccg
     1561 gccacgaacc aatcatgttg tagccgtcta caatcaacag ctgttttttc atggtctact
     1621 ccccctgacg ttgggaaaaa gcctgataca taagcaaacc agcagcaaca ctggcattta
     1681 agctctggac gtgcccggtc atcgggatcg tcagcaattc atccatttct tttttcaatc
     1741 ctggactcat tcctttgcct tcattaccaa tgactaaagc aattgatcct ttggcattcc
     1801 atttttggaa gtttgtgccg gtcatatctg tgccaaatac ccaaaatcct gtttctttga
     1861 gctgttgcac agcttgtacc aaattcgtca cgcgtgcaac agggacatgt tcgactgccc
     1921 cagtggaagt ctttgttacg ataggtgtga ttccaactgc tcggtgtttt ggtatgatca
     1981 caccatcgac gccacttgcg tctgctgtcc gtaaaatcga cccaaaattg tgtggatctt
     2041 cgatgctatc caaaatcaaa aagaaggggt cttctttttt ctcttttgtt cgttcaatca
     2101 gttggtcaag ggataaatat tcataaggtg taatcgcaag aacgactcct tgatgcacgc
     2161 cgtgatcgct caaagtttct aatttttgtt taggaaccca tttgactggc acagcttgtt
     2221 cacgtgcgat ttctttcagt tcttctactt tttctcctcg tgaatcttct tgaagaaaga
     2281 gtttattccc tcgcccttgt tgtagcgctt ctactgcggc atggtgccca aagacgaaat
     2341 tatcttctaa tgcttcttca ttttgatcag aaactgactg atttcgtcca gtttgctttt
     2401 tatttgaata tctattttgt tttttgtctt caaatccacg tttcgattga tgtttgtttg
     2461 ttctttcttt acccattttt ttcaccaact ttctgaatac accagcggat caattcttcc
     2521 atccgctcgg tttgttttgt caaatgcaga tagcccatga gcgcttcgaa ccctgttgcg
     2581 acccgatacg tcgtaacatc agcatttttt gcgctcgtat ggcttttagc atttcttcct
     2641 ctgcgataat aaagttcttc ttcttctgtc aaaagatgtt cttccagcat ttgctgaatc
     2701 aaaaaggctt gtgcattcgc agaaacataa ttcgttgccg cacgatgcag cttattgggt
     2761 tttgtttctc cttgatcaat caggtggtca cgaacataga tttcgtaaat cgcatctcca
     2821 acataagcca aggctaaacc gttcaattgt gtgtaatctc tcatgcttct cttctccatc
     2881 gggttccttg cggtgtatct tctaataaga tccctttttc tttcaacaaa tcacgaattt
     2941 cgtcgcttcg gacaaaatca cgattgcttc ttgcttgatt tcgttcttcg atcaattgtt
     3001 caatctcttc atctaataac tcttctgctg taaataaaat accgaagatc gaaagccatt
     3061 gcgagaataa agcttctcct tgtgccaaga cagcggcaga aactttcggc tggtctagat
     3121 aagtgttcag ccacttagca agctcataga ccactgtgat cccatttgct gcattaaaat
     3181 catcgtccat ttcttcgatg aatcgctgtt ctaaattttc taacaaagcg attttatccg
     3241 catcatctgc caaattctct gaggcagttt cttggcggaa tttcaaattg tcaaacgtat
     3301 tcttcagtcg ttgtaaattg gtggctgctt ctttcatcgt cgtttcactg tagcggatcg
     3361 gacgacggta ttgtgtggtc gccatgaaga aacgcaagac ttgtggatca acgtttttga
     3421 tcatttcatg tacagtgatg aaattcccta gagatttact cattttttca tcgtcttcgc
     3481 caatcgttac atagccattg tgcatccagt aattagcgaa ttttttccct gttttcgctt
     3541 cactttgtgc gatttcattt tcatgatgag gaaattctaa atcttgcccg ccaccatgga
     3601 tatcgatcgt ttctcctaaa tgttttgttg ccataacgga acattcaata tgccaaccgg
     3661 gacgtccttt gccccatggt gaatcccaag aaatctcgcc aggttttgct tgtttccata
     3721 aagcgaaatc taatgggtct tctttttgct gctgttcttc ccctgtacgc tgacttgctc
     3781 cgacttccag ttcatcgatg gattggtcac ttaatttccc ataattttca aatttacggg
     3841 tacggtaata cacatcacct gaagattcat aagcatagcc tttttcaacc aacacttgaa
     3901 taaatgctaa aatatctggc atatgatcca tgactcttgg atgcagtgta gcaggctcga
     3961 cattcaacgc tttcgtatct tcttcaaatg ctcggatgaa acgatcagca acttctggtg
     4021 ctgtaatacc taattcgttt gctgtacgga tgattttatc gtctacatcc gtgaaattcg
     4081 atacgaaatc gactttatag cctcgatatt caaaatagcg tcgaattgta tcgaaagcaa
     4141 tggtgctacg agcatttccg atatggatat aattatacac agtcggtccg cagacataca
     4201 taccgacatg tcccttttgt atagggatga attcttcttt ttttctggtc aatgtattgt
     4261 agatttttat cattctgatc tcctcacttt ttctcctttg attcgaacga cttttgctgg
     4321 tactcctacc gctgtagcgt cgtctggaac atctttcaac acaacggcac ctgcaccgat
     4381 tttggcgttt tttccgatcg ttaccggtcc taatatctgc gcattcgcag agagcatggc
     4441 tccttgttta acagttgggt gtcttttacc cgtttctttt cctgtgccgc ctaatgttac
     4501 gccatggaat aaaatcacat cgtcctcgat ttctgcggtt tcgccaatga cgattcccat
     4561 tccatggtcg atgaacacgc cagttccaat cgttgctcct ggatggatct caacaccagt
     4621 taggaaacgc cagaattgag cattgatctt cgccaataaa aagagccggt gctgatataa
     4681 aaaatgagag aaacgatgcc aaaacaaggc atgaaaacca gggtatgtca aaacgatctc
     4741 agctgtcgaa cgtgcagccg gatcgtttct ctttgctgca tcaatcgctc gggtaaacca
     4801 actcatgact ttccactcct ttcgtaagaa ttttatgtag gaaatcatct tcttataaag
     4861 aaaagaagcg ccttttaaat aagtttcctt atcaaaagac gctttccgcg tggttccact
     4921 tttcttcata atcaatgatt atctctgaca gctaacgcct gttatacgtt cttggctact
     4981 ttgtttccta taaaacagtt tttcctgttt tctgtgtttc gccaagacca ctcccagagg
     5041 catttcggca accattcatt gataccttgc accacccggt atctctcttg taatgatcag
     5101 ctgcttactt ttttctgttc atcgtgttta gttcagtact tgatttaaat gtgctaatga
     5161 tttttcacga ccaagcaatt cgatcgtttc aggcaattct ggaccatgca tttgtcctga
     5221 tacagctaca cggattggca tgaaaagatt ttttcctttt acgccagttt ctttttgaac
     5281 agctttgatg gcagctttga cagttggagc atctactact tccatttgtt ctagctgtgc
     5341 tttgaatgcg tggagaacag taggaactgt ttcaccagca agtacttctt ttgctgcttc
     5401 attcaataca ggatgttcat tgaaaaatag cgtagacaga tcaacgattt ctgcagcata
     5461 gctcatttga ggttgataca ggctaacgat cttcttcacc cattcgattg tcttttcatc
     5521 tgggttttct gctacacgtc catcagcgat tagataaggc agacacatgt cagtaaatgc
     5581 atctagatcc attgctttga tgtaatggtt gtttacccat tgcagttttt tcgcatcgaa
     5641 agctgcgggt gatttactta ggcgttttgg atcgaacatt ttgatcaatt cttggtgttc
     5701 gaagatttcg tcttcgccca caggtgacca gcccaataat gcaataaagt tgaacattgc
     5761 atctggtaga tagcctaatt cgcgatattg ttcgataaat tgcaagattg attcgtcacg
     5821 tttgcttagt tttttacctg tttcactgtt gatgatcaat gtcatatgtc cgaaggttgg
     5881 tggtgtccag ccaaatgctt catagatcat cagttgtttt ggtgtattgg caatatggtc
     5941 atctccacgt aaaacgtgag tgattttcat caaatgatca tcgaccgcaa cagcaaaatt
     6001 ataagttggc ataccatcgc gtttttgtat gacaaagtcg ccaccgatat tatcggattc
     6061 gaacgaaata gcgcctttca ccatatctgt aaatgcgtat tctgtattgc gaggcacacg
     6121 gaaacgtaca acagattcta gaccttgtgc ttctttttct gcttgttctt caggtgtcaa
     6181 gttcgcacat gttcctgcgt aatgaggcat ttctcctctt gcgcgttgtg cttcccgttc
     6241 tgcttctaat tcttcttctg tgcaatagca tttgtatgct cgattgctag caagcagctg
     6301 atcaatcagc ggttgataga tttctttacg ttcagattga cggtaagggc cgtattctcc
     6361 aggattttca ggagattcat cccaattcat tcccaaccaa gcaaggtttt ccaactggct
     6421 tttttcgcca tcttcgatat tacgtttttg gtcagtatcc tcaatacgaa taataaagtc
     6481 tccatcattg tggcgggcaa acaaataatt gaataatgca gttcttgcat ttccaatatg
     6541 caggtgccca gttggacttg gtgcatagcg tacgcgtact ttcgtcattt tcttcctctt
     6601 ctttcaaact agactttgac taacagcaaa aattccgtca gttacggctt ctcaaatatc
     6661 atttatttaa agccactcag cacaaatttt accttttcta aggtaaatag taaagccaac
     6721 tggttgaatt tccttaccag ttggctgaat ttctttttta ttttgattgt ttagtctttt
     6781 tctctgtctc ttttttattg tcgattcctc gtcctgcatg tgcaggttta gcaaagatca
     6841 tgcgtccagc agctgtttga agggcacttg ttacaacgac ttcgatacgt tcattcatgt
     6901 aatgctgtcc atcttctacg acaaccatcg tgccgtcatc aaggtaggct actccttgtt
     6961 ggcgttctgt cccggctttt actactagaa cattcatcgt ttcaccaggg atgacgactg
     7021 gttttacggc atttgccaac gcattgatat taagaacagg tacattttgg aattcagaga
     7081 ctttattcaa gttatagtca ttggttacaa tgacaccatc taaaagctta gccaatttga
     7141 tcaatttgct gtctacttca ctgatatctt caaagtctcc atcgtacatt tcgacagata
     7201 taccctcttc tttttgcaag gcatttagga tatctaatcc gcgacgacca cgcacacgtt
     7261 tcaaactatc ccctgagtcc gcgatgtatt gtagttcgta aagaacaaaa ttagggatca
     7321 tcaaggttcc ttctaagaat ccagtctttg taatatcata aatccgaccg tcaatgatca
     7381 cgcttgtatc caagatttta tatttatgga aattttctcc tgattttcgt tctaacagtt
     7441 gactctcaac ttgactagct gtttcttgct cgattttttt gcttcgtgaa ccaaaaactt
     7501 tcttccattc ttcgattcgt gtcgttccca ttctcaatcc cagatagcct aagatgatca
     7561 tcagtaaaat cggcaataca ctattgacga atggaatttc catattgtaa agaggggtcg
     7621 agatcacaac acctaaagtc aatccgatga tcgcaccgat cgcaccgaag agaagataag
     7681 tcaagctgac ctcacttagt ttttgttcta cttgtttgat aatagctgag atatgtttgg
     7741 ccaacagcaa agataataaa aagaaaataa gtgcgcctaa caggctgttg gtaaatgtat
     7801 tattcagcca tccgtttgac tgttgaccga ttgcctgcca agctgagggt aaaaatgaaa
     7861 tacccaagct tgcgccgaca atgatcatca gcaaagtaat gacacgtttt tgcatcgttt
     7921 ttcctccgtt tcgacaatca tttattagtt agcggaacac acgcttcaac gtttcagcca
     7981 aagttgctac tccaactatc tcgattcctt ttggcgcttc ccagttacct aagttgtttt
     8041 taggtaggta tacttttgtg aagccgagtt tttggacttc tttgactcgt tgttcaatat
     8101 gactgacacg tctgatttct ccagtcagtc caatttcacc gatgaaacat tccgttggct
     8161 gtgttccttt ttctttatag cttgaagcaa tactgacagc gatagctaaa tcaatcgctg
     8221 gttcatttaa ttttacccca cctgcagctt ttaagtaagc atcttgattc tgaagaagca
     8281 acccagctct tttttccagc actgccatga tcagagatac ccgattgaaa tcaagacctg
     8341 ttgttgttcg tttggcattt ccgaacatag taggtgtgac taatgcttgg atctctacca
     8401 aaattggacg tgtcccttcc attgccacaa cgatagcaga gccagttgca ccgtctaggc
     8461 gttcttctaa gaaaatctgt gaaggattag cgacttcttc caatccatgc tcatgcattt
     8521 caaaaatccc aatctcattc gttgagccaa atcggttttt tactgctcgc aaaatccgaa
     8581 aactatgatg ttgttcacct tcaaaatata acaccgtatc caccatatgt tctaacattc
     8641 ttgggccggc gatcgagcct tctttggtaa catgaccgac gataaaaatg gctatcccat
     8701 ttgttttagc gattttgagt agttctgcag tggtttctct tacttggctg acacttcctg
     8761 ccacacttgt gatgtctggc tgcgtcatcg tttggatgga atcaatgata acataatcag
     8821 gggagatatg ttcgatggca cgactgattt cgttcatatc tgtttcagcg tatagataaa
     8881 attctgtgtt gatacttccg aggcgttccg cgcgtaattt tatctgctct gcgctttctt
     8941 cgccggatac atataagact tttccgccta tggctgctaa ttgctgagaa acttgtaaca
     9001 gcaaagtgga tttcccgata cctggatcgc caccaatcaa gaccatagac cctggcacca
     9061 cacctccgcc taacacacgg ttcagttctt ctaattttgt tttgatccga ggttcttttt
     9121 tagggacgac gtctgcgatt tttgttggtt ttgctttttc tcctgtcaaa cttgtccgag
     9181 ttctgcggtc cgttgtatct tgttcgattt cttcgaccat cgtattccat tttccgcaat
     9241 ttgggcagcg tcccaagaac ttaggcgaca catacccgca attttggcaa acaaattgta
     9301 cttttgattt ttttgccatt gtaccgcctc cttttatcct aatcatgaga cattaaatca
     9361 agcttaagta tctttaacgt tttatttact ggaagaacca aatccgcctt gacgttgagc
     9421 agtcgtttga tcttgatctg cttttaaaaa cggcaaaaag atcccttggc cgatacgctc
     9481 gccttttttg atcactacat ccttgaaacc aaagttggtg aattggaaca tgatatggcc
     9541 ttcatttgcc tcattattgt aataatcact gtcaatcaca cctactccgt ttgtcaacac
     9601 taaaaaccgc ttcaacggat tgcttgaacg gttagcaagc tgcaaaaatt catcttctcc
     9661 catgtaagct ttgattccag taggcacgag ggttggtttc aattgttttt cattttctga
     9721 tacatctttt ttcaatccat ctgcgactgt ttccaacccc tttttccagc ctgctttcca
     9781 gatacttgga atcacgacct cttctgctgc ttcaaaatca tagccagcag catgatgtgt
     9841 agcgcgctgc ggtagattga tattttgatc tttatattta gaaataactt caaatcctct
     9901 ttttctcacc ggttttcct
//
LOCUS       DAFLWQ010000099         9811 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.102, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000099 DAFLWQ010000000
VERSION     DAFLWQ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.102"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..205)
                     /locus_tag="L1V16_002520"
     CDS             complement(<1..205)
                     /locus_tag="L1V16_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276809.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(221..835)
                     /locus_tag="L1V16_002521"
     CDS             complement(221..835)
                     /locus_tag="L1V16_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBN1276810.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(982..1665)
                     /locus_tag="L1V16_002522"
     CDS             complement(982..1665)
                     /locus_tag="L1V16_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBN1276811.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(1774..2232)
                     /locus_tag="L1V16_002523"
     CDS             complement(1774..2232)
                     /locus_tag="L1V16_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBN1276812.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(2316..4079)
                     /locus_tag="L1V16_002524"
     CDS             complement(2316..4079)
                     /locus_tag="L1V16_002524"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBN1276813.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(4300..5760)
                     /locus_tag="L1V16_002525"
     CDS             complement(4300..5760)
                     /locus_tag="L1V16_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276814.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(5968..6894)
                     /gene="glsA"
                     /locus_tag="L1V16_002526"
     CDS             complement(5968..6894)
                     /gene="glsA"
                     /locus_tag="L1V16_002526"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBN1276815.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(6917..8344)
                     /locus_tag="L1V16_002527"
     CDS             complement(6917..8344)
                     /locus_tag="L1V16_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1276816.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(8375..9589)
                     /locus_tag="L1V16_002528"
     CDS             complement(8375..9589)
                     /locus_tag="L1V16_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBN1276817.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT         2909 a         2040 c         1626 g         3236 t
ORIGIN      
        1 atttgttaaa gtaattaaac aatccgctaa tcgtttgatc tggcatttct atttccttac
       61 catctaaagt aacagtagta acgacaaaat ggtcttgcaa tggcggaact tctaagtact
      121 gcccttgcag aaaatcattc actgtttcat attctttttt catttctttt gaatctgtcg
      181 atggtttata gcttattttt aacataacta gtgctccttt ttattcggga cgtgcaatcg
      241 tgaaaatttc tcctattgct gcataatcat ttcctgccaa acggcttaca gcattcaatt
      301 ttcttggatc gatccttcct gtcttatcat catagactgt ttcatttaaa tgatatttct
      361 gtacttctag caaaaataaa tcagctgtta ctttattttt attccgtatc tcgacatgtt
      421 catataagga tgtttcaaaa cgaacttttg cttctgtcaa tgctggtact gaaatgatta
      481 ctgaatcagt taaagtcaag tcagtcaggt acagttcgct ttcctcatta ggcagattgg
      541 ctgctgtttt atttacttct tctacgttgt cctcatcaag gatatggata acagcttctc
      601 ttgtctcaag aatattcttt gctgtgtctt ttactgcatc ttgttttctc tggatcgcca
      661 aggataagat gggtcgattc gaactgacga tattgaagta actgaagggt gcgatattca
      721 ctatatcttt tgctgattta gtcgttacta ctgctactgg tctagggatg actgaaccaa
      781 tcagcaactt gtaattttca cgttctgtca attctgaagg actccgttca aacatggttt
      841 cgccttcttt ctataaaatt cgttaaaaag cagatcttga agacaaaatg aaaagtaatg
      901 cttttttcat cttcttagaa tctgctttaa actatctatc aatttttctt ttttgtcaag
      961 aatctgtgcc gtgcgtgttt tttagttatt tgctttactt gcggcttcga catatctttt
     1021 agtgatcaat tgcggacggg tgataataga tccaactacg actgaaaaag cacctaattc
     1081 atatgctttc tctacttgtt caggagagtc agtatgtcct tccataatta ctgggatatc
     1141 gacttgttct atgatttgat tcaataaatc aaaatcaggt gtctgcgtct ttcgtgaata
     1201 ttctgtatag cctgctaaag tcgtagacaa aagatcaaaa ccatcttctt gcgcttgaag
     1261 cgcttcctca aaagtcgaaa tatctgccat agctaaccga ccgtgttcgt gaatcatttg
     1321 gacaagttca gcagttgttt tttctgtcgg acgtttacga gaagttgcat ccagtgcaat
     1381 gatttctgct tgcgtctcca aaagttcttc cacttctttt tctgtcgcag taataaacac
     1441 ttctgaccca tcgtaatctc ttttgataat ccctattacc ggtaaatcaa cgattcgctt
     1501 gatttcattg atatcttctg tcgtatttgc tcgaatacca actgctccgc cttcttttgc
     1561 agccaaagcc attctcccca taataaaaga actgtgtagc ggctcgtttt ccaaagcttg
     1621 acaagaaacg acgactccgc ctttgatttg ttccagtgta tccacaatat ctcctccagt
     1681 aatgttatat aaaaatacag cttcatataa aaatgtaacc cttttctatt caggagacaa
     1741 taatgagcta tttctttcag cagacctttc ttactaaaag aaaattactt caaattcttc
     1801 gtatacgacc agcttctctt ctgtaaattc tatgttcaac gcttctttat aagcatgttt
     1861 aaaaaactca gcatggactt tccgccaata agctaatgtc cgatcccctt ctccttcttt
     1921 ccaagcatgc tctttcgtga cttcactaaa aggcaagatg gtcacattta tatttttgat
     1981 gatacaaact ggttcatttt ttccattcag gaccacgtct aattgaccaa cttttggtaa
     2041 aggctcattc tcttgtttat acagatcgta accacttgat gtaccagtct ttatcttttt
     2101 tacaactagt tcgctcaact cgtctgccat tttttctgta tccccaaatg aaaagaaacc
     2161 taatttttct gattgataac taggatattt ttcttggaac tttttgacat attcttctac
     2221 ttgctgatac ataacatcca cccctttgct ttttataatg aaaaaaccat ccagatacta
     2281 gtataaacaa ttatctggat ggtgagcata atgaattatt gaatattcaa gacacgcaga
     2341 ctatcttcaa cgatttgttt tggtgttaaa tgataacgtt cataaagctg ccctacagga
     2401 acgctatccg tgaattcttt ctctgcacca aaatttaata cgttcattga agaatcacca
     2461 taataacgac tgatattttc gccaaatcct cctgacaaac taccatcttc taatgtgatg
     2521 actaattcgt gtgtttcttt taatttatct aatgtttcta cgtcattttc tgtgatcgtt
     2581 cctggattga tcaacgttgc ttcgattcct ttttttctaa aagcttttac tgtttctttt
     2641 cctaattcaa gaaaaccgcc taaagctaaa attgctactt ttcctccatt atttactgtt
     2701 tgataggctg gaatactata atcatttgcg atagctgtac catgttctac accatgtgta
     2761 ggaattcgga ttgctacagg ctgcgctgtt tgttcgaacg cccaatctag catagagatc
     2821 atatcctctt ttgttgctgg agcaagatat ttgatgttcg ggatacttga taagtaagga
     2881 atgtcaaatg ttccttggtg tgttcggtca ctagctgaga tcgttccgcc accgactaaa
     2941 ataatcactg gattctcgtt gatcgctaaa tcatgtgata attgatcata tgcccgttgc
     3001 aagaaagtac ttgattggaa gacgactgga cgtactccct gagaagccaa agcagaagcg
     3061 aaagtgatag agtgctgttc agcgatcccc acgtcaaaat aatgatctgg atgtttttct
     3121 tggaatgttt tcagtccaaa ggcgcctggt atcgctgcat tgactgcggc aataggagct
     3181 gtacttgttt gcattttctt atccaaataa tccatgatga tcatattaaa tgtttctcca
     3241 gaagttactt gctttgcctc cccggtggac agatcaaatg gtacatgcca atgatatttc
     3301 attttattat cgattgccgg ctgataaccg cgaccttttt ccgtatggac gtgaagtaca
     3361 atcggatgat caatatcttt tacttcttca aataaacgga tcaccgtttc cagatcgttt
     3421 ccattatcca cgtaacgata atcaaatccc attgctttaa ataggttatt gctgctttta
     3481 ccgttggttt gacgaagctc agctaagttt ttatataaac tgccatgatt ctcatcaata
     3541 gacatctcat tatcgtttac taatacgatt agattggatt gtaaaacacc accattgttc
     3601 aatccttcaa aagctaagcc accacttagg gagccgtcac cgataaatgc taccacattt
     3661 cctgattctt tcttcagatc tctcgcttta gctaaacctg ttgctaagct gatagatgta
     3721 gatgtgtgcc ccactgtaaa atagtcatgt ttactttcat gttggttgga atatccgctc
     3781 acttcacggt aatgtccttt ttcaaaacca ttttttcgac cagttaaaag cttatgacca
     3841 taagactgat gggaaacatc ccaaacgatt ttatcctttg gtgaatcaaa tacataatga
     3901 aacgcaatcg ttaattctac tacacctaga ttcggaccaa cgtgcccacc tacatcgctg
     3961 tccttttgca agattttttg gcgcatctct tctgccaact gtttcatttc ctcaacagat
     4021 aattttttga catctgcggg gctattgatt gcatccaata catgtaatac tgtactcata
     4081 atacattctc tcctccgtac tatcttcttt taatgaaaat agatttgtta cactttatct
     4141 attctactac ttagagttga ctctaagtca atagcatttt aaaaaaattt cagagaaagc
     4201 ttgttatata agtagatctt cgcacgaatc aggactcaaa taaaaacctt ctacagacaa
     4261 ttaaaaagct ttgtagaagg tctcctaatt aaggtctcat caagaaatat gtttttttaa
     4321 taggtgaagt tcctgagcaa tatgatacaa atggatgttt gcacctttta atgagattgg
     4381 atagatcttt gtcttttcag tttctaatcc attttgatag ctagcagcat cgcacaaaac
     4441 cactcttttt ttcgcacata gacattcatc aggcaattct tctaatgaac gaaataaaat
     4501 aggatttatt tcagcgatgc cttcttccgc atacaaatga aattgggttc gataaaaaaa
     4561 ttgtttgact gaactttctg aaacaacaaa aatttctatt tcctgtctcc ccgcttgttc
     4621 actgttgatc aaagaaagac ttttgacgaa ttttcgaatg aaattttcat tccatcttag
     4681 ttggatttga tttttctttt tccactcttc caatatttct acaatttttc cgtacagaag
     4741 ttgttctttt tctgatagaa gatagatcct ttccggtaaa aatacttgtc catctgccca
     4801 caacgtacgg acaaattgta aaaaggattg cttgaaaata aaattttctg catcgtcgat
     4861 ttcagcgata ctaataatct gtaaaatcaa ttcattcagt gataggtcat tgagaacaaa
     4921 atttttataa acaacttcga aatcttttct taacagctcc atgttctcat tggtataatt
     4981 tctactgttg aacaaagaaa aaatataata gacatcttct tcttgtaagt ctagaattcc
     5041 tttttgctct tccaatcctt gacagactaa ttgaaataac ggcttcgttt ctgcgctttt
     5101 cttatcttct tctttcagtc caaggggaaa tgcctttctt ccgattgcga tctctattcc
     5161 tcgtatgata aaggactttt catcttccga atatcttctt ttaaaaaaat gagtctctac
     5221 ataatcaatc aactcgttac aagcttcttc tacatacgga tttttatttt catagccttc
     5281 ccaattgaca taacgtacta aagctagcaa gatgttccgc gagtcaaatt ctgggataat
     5341 gatttcttta tttttcaaat aatcattttc tttaaaaaaa tccaatacga tttttttgat
     5401 tgtatatact ttgctcaaag aaataaattc aagatcagcc agttctgtac tcgtgaatat
     5461 accattaaaa taataactta aaaactttaa aaaataagat tgaccgtaca gaaactgtgt
     5521 gagctcagaa agagcaatac catgtttgaa tacgagttta tacttatgct tctctcttac
     5581 ttgttctttt atacaatatt ctagacactc ggctagactt tctagatcgt gaaggatcgt
     5641 tggtgtagtc acccttagag aaatagctgt ttgttcgatg tctatttctt ggaattcaaa
     5701 taattgttca cacagataca cttttctaaa tatatttcgc tcgatgtaat tttccagcat
     5761 tcctgataca cgcctccagt ttttcttatg attttattta atcatatctg taaatcgtat
     5821 ttttgtttcc tttttattta gaaaagccct ttcaaaaacc aataaaaaaa gaaactggga
     5881 caaaagtcaa acaagctcac aatttcagcc tcattgtagg tagctttgag ccgtttggac
     5941 ttttacccca gcctctttca agaatggtta ttcaaagatg tcagcgtcta gttctttgac
     6001 tacatctttc aacaattgga taccagctgc gctgttacca aatggatcta gtgccgggct
     6061 gaagacacct atgccgtaac gatttggcac agctgccatc aacccgccgc ctacaccgct
     6121 ttttgcaggt acaccaacat ggacggaaaa ctctcctgat tcatcataca aaccagcagt
     6181 tgtcataatt gatttgacga ttgtagcact ttcttcagta atgatttgtt tgccattcca
     6241 aggagcaatt cctttatttg ccagcacagc agctaatttt gctatgcctg tagcggtgac
     6301 attgagggag cattgtctga aataagcatc gagtatctcc ggtacgtctc cttcgatcat
     6361 ttgattacct ttcatatagt aagcaagaga gcgattgata tcacctgttc ttgattcaga
     6421 atgatagatt tcttcattca atgtgatatt aggatcatca cagatctctt tcataaatga
     6481 caagattcgc tcaaattttt catctgcatc tttaccggca atcaacgagg ttgttgcaat
     6541 cgctcctgca ttaacaaaag gattcattgg atgtttgcga tgattgattt ccatattcat
     6601 gatagaattg aaggcaaaac cggttggttc cgtgttgatt gtttgaaaga ctttttctat
     6661 tccgttgtct ttgattgcta ataacaatac gggaactttt gacatgcttt cgatggcaaa
     6721 gcgcacatcg gcgtctcctc cctcaatcag ttgttttgta tccaaatcat aaatcgccat
     6781 acctaattgt ttgggatcca cttcagctaa tgctggaatg taatccgcca cttgtcctgt
     6841 ttgataatag tggaaatttt ttccaatcaa ttgttctaat tcttttactt ccatttgaat
     6901 aaccagcttt cattttttat ttttctgcat gctggaattt atgacggcat gcgtagatcg
     6961 taaatggaat aactaagacg ataagataag aaacaatcag aatcgtttca taaatcccat
     7021 gctgtccagc tgcgatacta gcaggtggaa caaatgagat acaaaaagca aaaagtgaag
     7081 tcaaaagacc taaacaagca acgattactt ttacaacttt tccgcctgga acctgatagg
     7141 ctctttcaag actgtcatct ttaaaaacca gcttcaaata gcccgcgaaa aacataaagt
     7201 acaacatcag gtagattaca acagtcaatg acatcgctgc aagaaatgaa agattattcc
     7261 ccccgccgct taatgtaaag acggctgccc agattgttgc aacgatccca tttgcgatca
     7321 tcaaatgagc aggaacaccg tgtgtgtttt cttttgcaaa atattcagga agtaatcctt
     7381 cttctgctgc tacgtgaagt gcttttgaag gagaggttac ccaagaagca atttctccga
     7441 tgacacctaa acaaacaaga atcgcaagaa ttttcgcaat ccatgcaaga tttggatcaa
     7501 tgtgtcttaa taggaattct aacgattgaa tcacccctgt attaagagac aaaccatgtt
     7561 gaggtactgt agtagcgacg gtcaatccgc caaaagtatc taaaatgatt gccagaataa
     7621 ccaatacaaa cattgctaat ggataatcct ttttagggtt ttccatttca tttgcatgac
     7681 tggcagatgt ttctacgccc atatatgcta aaataaagga aacaaaaaca accagcgtag
     7741 gcaatttcga aaaatcagga atcaatgttt tcatagacag tatcgtttgt agtggagcgc
     7801 ctgaagcgac ataatggatc cctaagccaa acaagactaa tgctggcaac aagataccag
     7861 ctacaaaacc gatccgagca atcaatgaag tgtatttggt tccttttaac tgtgagagta
     7921 aaatagccca gaaaataatc aataggattg ccaatttcag atatttattg ttttgtatag
     7981 caccaatacc cgttgcatag gataatgcac cagttaagaa atacagcatg gtcaagtagc
     8041 caactgttat ctcaaaccat tggaaaaaga ttgcggcaaa accgaatcgt tttcccaatg
     8101 tgcgactgac ccaagtatag acaccgcctt tttcccatcc tttcaccgtt gccatctctg
     8161 ctgcgcacaa tgccacaggg ataaaccata gcaaaccgcc taataacaag aaaaatacta
     8221 agctgaagcc tgaggtcgcg aatgtgggat attcatataa tgaaacgacc attgagatgg
     8281 tcatagccaa aaagccaaag aacgttaatt tttttgcagg aattttcgtt ttgctttgtt
     8341 gcatgaatct tcctcttttc tatttgaatt tgtttcaatt gagtttgttg ccaaagaaga
     8401 aaaagtccaa tccttcttct tgttcttctt ttgtagtagt gatcgttgta aagtgcatcg
     8461 ccgattttaa aatcactgtt gtcagcacat aggcatacac ggcagtaatg atgacaccaa
     8521 tcacttgaat ccctaagaag taccagctgc ttggattcgt tagtaaatgg ctgttagatg
     8581 caaagatccc tatcagaatc gtacctgtga atccgcccat gccatgaaca ccccacacat
     8641 caagtgcatc atcccattgt ttctttttac gaaaatcaac agcagcatga cagacgatac
     8701 ccgcaatgat cccaatcagc atggcacttt ttgcttctac ataaccggca caaggcgtaa
     8761 tggctgccaa tccagcaacg gatcctgtta gtacgtcgac aaaatcaaag ccatttcctt
     8821 ttacttttgc aatgatcagc caagtaatca tcgcaaatgc aagagcgatg aatgttgaac
     8881 caaatgcatt gactgcttgt tcatctgctc gaagtgcacc accggaatta aaaccgaacc
     8941 agccaaacca aagcagtcct gtaccgatag cagctgccat aagactgcta tgctgacttc
     9001 tttctcctaa aggaatcttt ctttgaccaa gtgtgaggat acatgctaaa gagccgaatc
     9061 cagctgtcgt gtggatgact gctccaccag cgaaatctct aaatcccatc tgatccaaaa
     9121 atccgccacc ccatatccag tggcaaacag ggaaataaat cagcagattc caaaaaataa
     9181 caagtataat atagcctttt aaattcaatc tccctgcaaa agctcctgtc atcaaaggaa
     9241 cggtaatcac gataaacatc agttggtaaa gaaagaacat taaaaatgga atcgttgcac
     9301 catgaaacat gttggggaag cttgtaacat gtctcatcaa aaagaaatct gccgggtttc
     9361 caataacacc gccgatatcc cgtccaaagg ccaatccgaa tccaccaaat acccacataa
     9421 tcgttgttat cccaacggag agaaaagatt gagacatgat cgttagtata ttattcttcc
     9481 gtgctaatcc gccgtaaaaa aaagctagac caggagtcat caggcaaacc attgctgtac
     9541 ataaaatcat gaatgctgta tctcctgtat tgataggtaa tgtattcatt tttttcgcct
     9601 cctttctacg attacgagta taaaagaagg tgtagttgtt tttttcttct gtttttttga
     9661 attaatactt gcatttataa aagacagaca attaataaaa gcttgatgtg ttgtgctctt
     9721 tttcgttttt cacacaaata aagacaaaaa ataaacggtc ttctttttat agaaaaccgt
     9781 ttattttcgt ctttttttat ttttaaagat a
//
LOCUS       DAFLWQ010000100         9729 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.103, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000100 DAFLWQ010000000
VERSION     DAFLWQ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.103"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..777
                     /locus_tag="L1V16_002529"
     CDS             <1..777
                     /locus_tag="L1V16_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1276818.1"
                     /translation="KSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCSA
                     RTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSIT
                     FDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDE
                     FFIQSVASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            838..1047
                     /locus_tag="L1V16_002530"
     CDS             838..1047
                     /locus_tag="L1V16_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276819.1"
                     /translation="MICYISFLILGLPQAVFPEMFSGDWGIVSYSILTLIAMVLGTSF
                     YNAFVSKHVEEYEVLMYLKEKKTSN"
     gene            1254..1454
                     /locus_tag="L1V16_002531"
                     /pseudo
     CDS             1254..1454
                     /locus_tag="L1V16_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2166..2771)
                     /locus_tag="L1V16_002532"
     CDS             complement(2166..2771)
                     /locus_tag="L1V16_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1276820.1"
                     /translation="MAKIGYIRVSSQDQNLDRQLAMMEDLNIDKLFQEKASGKDIQRP
                     EFQKLLNYIREGDCVIVASLDRLGRDYEDIKNTVTFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAKKAGRYKGRPIEYSENSTDPQ
                     KRLVFKTVVDMLNQGVPVAEIAKENGLSRPTIYKIKKANDL"
     gene            2953..3288
                     /locus_tag="L1V16_002533"
                     /pseudo
     CDS             2953..3288
                     /locus_tag="L1V16_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            3453..3680
                     /locus_tag="L1V16_002534"
                     /pseudo
     CDS             3453..3680
                     /locus_tag="L1V16_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613886.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            3806..4777
                     /locus_tag="L1V16_002535"
     CDS             3806..4777
                     /locus_tag="L1V16_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1276821.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            4917..6230
                     /locus_tag="L1V16_002536"
     CDS             4917..6230
                     /locus_tag="L1V16_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBN1276822.1"
                     /translation="MKKRMLAIAAILALTAGGLAGCGSKEKSSGSSDPGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFIWSNGGDVVNADGTKAEDYFNGKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMMLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQLSGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            6273..7139
                     /locus_tag="L1V16_002537"
     CDS             6273..7139
                     /locus_tag="L1V16_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1276823.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQIGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            7136..7984
                     /locus_tag="L1V16_002538"
     CDS             7136..7984
                     /locus_tag="L1V16_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1276824.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            7998..9470
                     /locus_tag="L1V16_002539"
     CDS             7998..9470
                     /locus_tag="L1V16_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HBN1276825.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWMNDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMIAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQERIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPDHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            9487..>9729
                     /locus_tag="L1V16_002540"
     CDS             9487..>9729
                     /locus_tag="L1V16_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1276826.1"
                     /translation="MIYGSIEAGGTKFVCAISDEEMTIKERVSFPTTTPEETIPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPK"
BASE COUNT         3090 a         1646 c         1985 g         3008 t
ORIGIN      
        1 aaatcaaact gtggtagacg tccgcttgtt ttacccgagg aacaatcaga atatattcaa
       61 agaaaggttg ttcaaggatg gacacccgat gtgattgttg gtcgtgcagc gtttcctatt
      121 agttgttctg ctcgtaccat ttatcgtatg ttcaaaaagg ggctatttga ttcttctgac
      181 ttaccgatga aaggcaagcg taaaccgaat ggacatcaag aaagacgtgg aaaacaaact
      241 ttccgccgct ctattcatga acgtgaaaag gattatagcc aattctcaaa tgagtttggt
      301 caccttgaag gtgacactat cgtaggtctg aaacataaaa gtgctgtaat taccttagtt
      361 gaacgattat caaaagttat catcacattg aaaccgtgtg gtagacaagc gattgatatt
      421 gaaaaaaaat taaatcaatg gtttgaatct gtaccgaaaa acctattcaa atccatcact
      481 tttgattgtg gaaaggaatt ttcaaattgg aaacagatca gtaatgtcaa tgatattgcc
      541 atttatttcg ctgatccagg aacgccgtct caaagaggcc taaacgagaa ttctaacgga
      601 ttgttacgta gagatggttt attgaaatct atggatttca attcagtaga tgaatttttt
      661 attcaatctg tcgcatctaa acgaaataat attcctagaa aatcactgga ttatcgaaca
      721 cctttggaag tatttttgag ttacgtaagt attgatgatc tgtctaactt aatttgacaa
      781 ttaagacatt taaaaagaaa agtgacagat aggaataaaa acttattaaa tgtagttatg
      841 atctgttata tttcatttct aatactaggt cttccacaag cagtgtttcc tgaaatgttt
      901 tctggagact ggggtattgt cagctattct atattaacat tgattgctat ggttttaggt
      961 acttcatttt ataatgcttt tgtaagtaag catgttgagg aatatgaagt attaatgtac
     1021 ttaaaagaga aaaaaacaag taattaatat gagaacacca cgcatagttt ttattttgag
     1081 atattctaga atgaaacaca ttaagaacga aagcaaagca aaagacgcca gaacttctac
     1141 taccttctaa gttttttcat atttgtttgt tatgctatac atagatctgc ataattagac
     1201 ttgcgctgcc cgttattgaa gtttcaggca gcgctctttt tgggggatcg ataatggaag
     1261 aagaaaaaat atttgagaaa cgctggcagc tagcatcaag tgaacaaaga gcaagataca
     1321 ataatttgat cacctcctac cccactgttg actagacata taaggaaaag aaatacttac
     1381 tttggctgtg ccagttagat atagatacct ttgaaacatt tgaagtgatc ctagataaaa
     1441 ttaaacagaa ttgatcagaa acaagcgaag ccttctctcg gttcgcttgt tttgctattt
     1501 attagttggc tcagggcaac tctaagctcg tttgaaagaa aaccgatgga taatcccctt
     1561 gtttgtacca ctttagaata catggatgta cgtattgcca ttgactccta ttagttactg
     1621 aaaaaaaatt taaacaagtt gagtattgca gataaatagc tccagtgagg tgaataactg
     1681 ctccactcaa ggcaatagat agctccatcc agggcaacaa actgctccac tttcatattt
     1741 aatagatgaa taaccttctg tataatagaa aggcatacct ttcggtatga caacttatac
     1801 agaatgttat tttattggtt cactatcgaa aaattttgga gctttatttt tccggtattt
     1861 ctcaacgaac gattagttta actgtgggaa gctccagaca tacgattcga gaagttactt
     1921 ctcgagcaga caggaagggg gtgactgaac taaccgctga tatgagcgat acttggctgt
     1981 aggaatatct ttttccggaa aaacaaacaa cagcacgagg ttaccttcct gtagactggg
     2041 aatatgttca taaagaacta atgaaaaaga atatgacatt gaaactcctt catagagaat
     2101 atggggtaca tggaacatag aaacgaaaat gcacggtaga aaagcgaatg aatatagtat
     2161 aaattctaca aatcattcgc tttctttatt ttatatatgg ttggtcgaga gagaccattt
     2221 tctttggcaa tttctgcaac tggaactcct tgatttaaca tgtccaccac agttttaaag
     2281 actaatcgtt tttgcggatc tgttgagttc tcagaatatt caattggtcg ccccttatat
     2341 cgaccagctt ttttggccaa taatactcct tgccgctgac gttcacggat tttctcacgt
     2401 tcgttttgtg caatataact tagcaatgat aaaaacatat cgaacatagc agtatctagg
     2461 agttcatttc cagtattaaa atctaaaaac tgtgcatcta gtatttttaa tgctactttt
     2521 ttctgtttca taaaggtaac tgtatttttt atgtcttcat aatctctgcc taggcgatcc
     2581 agtgatgcaa caatgacaca atcaccttct cggatataat ttagtaattt ttgaaactca
     2641 ggtcgctgga tatctttacc actggctttt tcttggaata atttatcaat gttaaggtct
     2701 tccatcattg ccaattgtcg atctaaattt tgatcttgtg aagacactct aatatatcca
     2761 atttttgcca taaaaactcc ttttaaaaaa tgatataatt tacatgtaaa atttacttgt
     2821 agttttactg ttatcatagc atttttaaaa ataaatttta agtctactta taatttactt
     2881 tggaggtttt gaatgaatga aattaagcgc aataaaaatt cttttggtgt ttatttagga
     2941 gagcctagct cggaacagtt aaataaaggt gaagctcgtc atgctctatg tcgaaatata
     3001 ttttatggta gaaaaggcaa actttatcaa acttattacg acggtatgga ggaacagctc
     3061 aacgcattag gattagtaac taatgctatc atatattgga attcactata tttagaaaaa
     3121 gtctttgaac aaattaaaac ggaagggttc gactgttccg aagaagtgtt acgcaagcaa
     3181 tttccattaa ttagtgatca cattaatttt gttggcaaat atagtttccg ctatgaaaaa
     3241 gaattatcga atggaatact acgtccgtta aatatagaga attattgaga atgttcgtct
     3301 tttggttcct accgtgcatt ttcgcacgga tgttccagat actatttttg aatgtataaa
     3361 attgaaaaca caagaatact aataaatcaa cgattcttgt gtttttaatt tttcactacc
     3421 gtgcattttc gtttctatgt tccatgtacc ccaatcttga aaaattaatt aaagacttag
     3481 ataaagccat tgacgactta gtcgtggtgc taccggagta tcaatgttta accagtatcc
     3541 caggtattgg tcctgtttag gctgctggaa tactcgctga aattggtcca attgaacgtt
     3601 tttctgatga aataaaattg acaaagtatg ccggcctata ttggcgacag agtcaatccg
     3661 gtaaatctga atacgaaaat ttttttacga aaagcttcac gtctaatatc tattttaaaa
     3721 taaaaatatt cctgctaatt tggaatcgtt tccttctttt ggtataataa tacctgaaat
     3781 tcttttgaga ggagttgttc gtgaagtgaa aactactatg aaggatgttg ctgcgttagc
     3841 aggagttggt gtgggtacgg tatctagagt aataaatgga gtaaaggtga aagaggttac
     3901 caaagaaaaa gtaatggctg caattagtga gcttaattat gagcctgatg aatatgccag
     3961 aggtatgaaa acgaatagta gcaatacaat agctcttatt ttacctacga tttggcatcc
     4021 cttcttttcc gagtttgcct actatgtaga ggaagctctc agccaaaaaa attataagct
     4081 ttttttgtgt aatgcgaacg gcagtgcgga aaaagaaaaa gaatatatcc aaatggtcaa
     4141 gcagagtaaa gtagacggaa ttataggtat tacctattca gacattgata aatatgtatc
     4201 atcaaattta ccatttgtca gtatagaccg ccatttttcg gaacaggttt cttatgtaac
     4261 ggcagataat tatttaggtg ggcaaattgc cgctcaagaa ctacttactc gtaactgtaa
     4321 aaacttgtgc tatgttgggg gtgtttcacc ttaccctaac gaaacaaaca atcgtaaagc
     4381 tggtttttac aatatttgtg aggaaaataa aatagctgtg aaggtattgg atatgcctga
     4441 accaattagc aatttagagg aacaattgct cgcttttttt tcggataatc ctgaaattga
     4501 tagcattttt accatcaatg atttcatggc tttggatgtg ataaaagccc aaaaaaaact
     4561 agggaaggaa gcacctaagg attttcaaat tattggtttt gatggagtca agctatcgtt
     4621 gcaaaaagac tatttactat caacgattgt acagccgata gaggaaatgg ccaaggtttc
     4681 agtagaaaca ctcatggcga tgattttaaa tgaagaaccg cctaagcgtg tggtagtacc
     4741 ggttttcttt cacgctggag agacgactaa agagtaaaaa accggtttat aacgattttt
     4801 ttgagatagg ttgacagaaa gtgatttcaa tgatatctta aaaccaatta attggaaacg
     4861 ttaccaatta attgaaaaat aaaacggaaa cgtttcaaaa aataggagga acatcgatga
     4921 aaaagagaat gttagcaatt gcagcaattt tagcattaac agctggagga cttgcaggat
     4981 gtggcagtaa ggagaaaagt tcaggtagca gtgatccagg agaaattaag atttgggttc
     5041 agttttctga tgaaacgcct gaaggaaaag cttgggcaga gattgtgaac aattttaatg
     5101 atgaatacga gggtgaatat aaagctgtta ctgagtatat tcctcgtagc ggaagcggcg
     5161 gtggatatga ggataaagta aatgctgcaa ttacaaccaa tacccttcct gatgttatta
     5221 cgttagatgg accgaatact gcagcttatg ctcattcagg agtcattgct ccattagatg
     5281 attatttgaa agatgcggac atggatgatg tattagacag cattattcag caaggaacct
     5341 acgatggcaa aatgtatgcg tttggtttct cagagtccag tgtgggtgtc tattacaata
     5401 agtcgctgtt caaagatgct ggaattacag aagatcaatt gccgacgtta gaagatcctt
     5461 ggacttggac ggaatttcaa gcaatttgcc aaaagctgac tgataaatac aaaacgcctg
     5521 caattgatat gcaaatggcg tcgggagacg aaatgctgac ctacgcatat acaccattta
     5581 tatggtcgaa tggcggcgat gtcgttaatg ctgatggaac caaagccgaa gactatttta
     5641 acggtaaaaa atccgttgaa gcgttggaat ttattcaaga attggttgaa aaaggttaca
     5701 ccacaatcag tcctattgaa aaaggatttg aaactggcaa atatgccatg atgctgagcg
     5761 gttcttggac aatggcagat ttagaggaaa actatcaaga gattgattat ggtattttgc
     5821 cttaccccgt ttcagatgca actggggagt tagtttcacc aaccggaagc tggcagttag
     5881 caatgactga gaaaacagag aaaaaggatg cttctgcggc ctttattaag tttgcaacca
     5941 gtacagaatc tagtcgtatt atgagtttag ggaacagtgt tctacctatc agaaattcaa
     6001 cagttgattt aattaaagat gaagtgtcgg aaggaatgca ggtattaatt aagcaaaacc
     6061 aactttctgg acatgcccgc ccagtggttg tagcttatcc gcaagtatct agagcattcc
     6121 aacaagcagt tcaagatatt agctacttcg aggaaaaccc agatgtacaa aaagtagcag
     6181 atagtcgcgc tgctgaaatg caacaggcaa ttgatacttc actaaaatag aagtttctaa
     6241 agggggccaa tcaagtgtta aaaaaaccga caatgaaaga caatttgata ggttacggct
     6301 ttctagcgcc agctttgctg ctgctgacga tttttctgat catacccgta atcatggtaa
     6361 tttattatgc ctttactgat tattatttgt taacgccaga tgctagacaa tttatcggct
     6421 tagaaaattt taagcgactg ttcgctgatc caatttttgt aaaaagtatt tggaacacgg
     6481 ctaaatttgt tgtttggatt attccggtcc aaataggggc agctttagga atggcactta
     6541 ttatcaacaa aaatcgtaaa ggaaatatct tttttaaagt agcctttttt gcgccagtcg
     6601 tgatgtcctt agtcgttatt tcgattttat ggttgtactt gttaaatcct aatgaaggtc
     6661 tggttaatac gctatttgca aagattggaa ttgcttcgca gccttttttg actagtccca
     6721 aacaagcaat gtatacgctt gttttcgtat cggcatggca aggtgcagga tatcagatgc
     6781 tgctgttttt agggggaatg caaaatattc cgcaagacgt ttatgaggca gccgaaattg
     6841 atggtttttc taagtttcag caatttcgct atatcaccat gccattatta aagcccacgg
     6901 cgatttttat tttacttacc acattgattt cggcctttaa actaatcatt cagccaatgg
     6961 taatgactca aggtggacca atgaattcta ctatgacaat ggtttattac atttaccaaa
     7021 ctggatttac agaccgtatg gtaggctact ccagctccat tgcgttaatc tttaccacta
     7081 tgattggttt aattacaatt gctcaaagaa aattggtaaa ggaggatgat ccagcatgac
     7141 caagaaattt ggaccgctaa tgatcgtaga atattgtttg ctgttccttt tagcggcatt
     7201 attcattttc ccgatgctgt ggatggtagt ttcctctatg aagcctgaag cagatgtcta
     7261 tcaaaattta gcttccttca aagctttttt acctagtttg aatccagcta attggtttaa
     7321 aacttatcaa gaggttattt cccggttcag tgtgggaact tatttattaa acagtatttt
     7381 ttatggttta acctttgcct gtgggtcaat cattgtaaac tctttggcgg gttttgcctt
     7441 tgcgaaggtt aatttttcag gcaagaaaat tatctttgga gctttgttag ctctgctgat
     7501 tgtcccgatg gagacggttt taattccgca atttaccatc gttaattcac taggcttagt
     7561 gaatactcgc ttggcagtga ttttaccagc gatggccagc gcgtttaata tctatctgtt
     7621 tagaaatttc tttatcgcga ttccagaaga aatcattgaa tcagcgaaat tagatggtgc
     7681 aaatattgtt aaaattttct ttcacatcat gctgccaatg tctaaaccag ccatagccac
     7741 agtaggtgtc ttatccttta tctccagctg gaatgattat atttggccgt taatggtctt
     7801 aactgacagc agcaaatttt caatgcaagt ggcaattact acgatcaata ctacacagcc
     7861 agtttatatc aatcaagtga tggctgtttt aaccattgca acgattccac tgattattgt
     7921 ttatatcgtt gcacaaaaat atattctgca gggacttggc ggttctggaa cgggtataaa
     7981 ataggagtga atagtgaatg ttgcaaaaac ttttaaaggc caatgagttt attgagaaaa
     8041 atgctcaaac agtcaatcaa gaataccgga ataaatttca tttgatggct ccgattggct
     8101 ggatgaatga tccaaatggt tttgtttatt atcaagagga gtatcacttg ttttatcaat
     8161 attatcctta cgacagcatc tggggaccaa tgcattgggg ccatgctaaa agcaaggatc
     8221 taattcactg ggagcatttg ccagtagcac tggcaccagg tgaaagctat gacaaggaag
     8281 gctgtttttc cggcagtgcc atagaaaagg atggcaagct gtatttgatt tatacaggac
     8341 acaatgttgt ggaagggcaa gttcgacaag ttcagtgttt ggcagtttca gaagatggca
     8401 ttcactttga aaaatatgcc ggaaatccaa tcatcgcaga agatcactta gcttctgttg
     8461 caacgaccga agatttccgc gatcccaaag tgtttcagcg aaaagaagac tattttactg
     8521 tagtcgctac taaaactgca gatgctcgtg gacaaattgt gatgttccat tccaaagatt
     8581 tactaacttg ggagttttat tccgtattgc tggagggaac tccagaacaa ggcattgtat
     8641 gggaatgccc agacttgttt gaactagatg gcaaagaagt cttgattctt tctcctattc
     8701 aaatgactcc acaaggcaat gcttaccaaa atacgaactc aactgttgct ttcatcggta
     8761 ctgtcgattg gcaaacaggc aaatttctag tagagaattt tcatgaaatc gatggcggtt
     8821 tagattttta tgcaccccag acctgtgaaa acgaagcagg ccaaagaata atgattgctt
     8881 ggatgcaaat gtggcagcgt aaaataccta cgaatgatct gggccatggt tggtcaggtt
     8941 ccatgacctt gcctagagag ctgagggtgg ctgataatca attgttgcaa cggccagttt
     9001 catcaattta tcaagtaatt gatccgcagg aaaggattga atgggcgaag actgaagaga
     9061 atcgcttctt actgaaggac ttagtatatg accagcacta tttacgcttg gaaatcaatt
     9121 taaaacaggc aacgaaacta gaacttcact atgcgaaggg acccgaccat acattactgc
     9181 ttaactatga tgttgaacgg gagtgcttta ctgcttccag ggaacacatg ccgtatgatt
     9241 tatcaggagc tgaaaaggaa gtgttgaaaa agcgcagtgt gacgattcct ttggaaaata
     9301 attgtctaac catcgaaatt ttccgtgata cttcagctat tgagcttttt ctaaatgatc
     9361 gtctgactat gagtacaact ttttatgaga cagaaaaagg acaggatttt cttttgctgg
     9421 cagacagtga agtaaccttt tcattggaaa gcggcttaat taatctatag aagggagagc
     9481 tcagtgatga tttatggttc aatcgaagca ggcggcacaa aatttgtgtg tgccattagc
     9541 gatgaagaaa tgacgatcaa ggaaagagtg agctttccga caacgacacc tgaggaaaca
     9601 atacctttag tcattgactt cttcaaacaa taccaagcag atttagcagg gattgggatt
     9661 ggctcatttg ggcctatcga tatccatcgc gattccgcca cttatgggta cattacctcg
     9721 accccgaaa
//
LOCUS       DAFLWQ010000101         9449 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.104, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000101 DAFLWQ010000000
VERSION     DAFLWQ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.104"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            126..320
                     /locus_tag="L1V16_002541"
     CDS             126..320
                     /locus_tag="L1V16_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276827.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            589..888
                     /locus_tag="L1V16_002542"
     CDS             589..888
                     /locus_tag="L1V16_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276828.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(985..1419)
                     /locus_tag="L1V16_002543"
     CDS             complement(985..1419)
                     /locus_tag="L1V16_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1276829.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1651..2361)
                     /locus_tag="L1V16_002544"
     CDS             complement(1651..2361)
                     /locus_tag="L1V16_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBN1276830.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2351..3211)
                     /locus_tag="L1V16_002545"
     CDS             complement(2351..3211)
                     /locus_tag="L1V16_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBN1276831.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3216..3854)
                     /locus_tag="L1V16_002546"
     CDS             complement(3216..3854)
                     /locus_tag="L1V16_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBN1276832.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3869..4168)
                     /locus_tag="L1V16_002547"
     CDS             complement(3869..4168)
                     /locus_tag="L1V16_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1276833.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4211..5695)
                     /locus_tag="L1V16_002548"
     CDS             complement(4211..5695)
                     /locus_tag="L1V16_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBN1276834.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5715..6176)
                     /locus_tag="L1V16_002549"
     CDS             complement(5715..6176)
                     /locus_tag="L1V16_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1276835.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6194..7261)
                     /gene="ulaG"
                     /locus_tag="L1V16_002550"
     CDS             complement(6194..7261)
                     /gene="ulaG"
                     /locus_tag="L1V16_002550"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBN1276836.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7479..8249
                     /locus_tag="L1V16_002551"
     CDS             7479..8249
                     /locus_tag="L1V16_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1276837.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8522..9349)
                     /locus_tag="L1V16_002552"
     CDS             complement(8522..9349)
                     /locus_tag="L1V16_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1276838.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
BASE COUNT         2945 a         1934 c         1482 g         3088 t
ORIGIN      
        1 tatatcgagt gaaaaaaact ttcaaattga ttctttttat ttatcataaa gatatagata
       61 cataatcatt ttcacttaca tatatttgaa tattaactaa aaacagcaag aaagaagagg
      121 atcaaatgta ttatgtagaa gtaaaaacaa aaggcgtcaa aaacaaacaa tatgtgaaag
      181 gtatcagtaa cgaatatcct ttacttggtt catggaaaga agctgctcct ttttccaaac
      241 catgtgccat aaaaataaag aacgagctag aaaaagaact gacttgtggt aaagctgttg
      301 tagatatcat cgaaaagtaa atccaatgta tagaaaggaa gatcacacat gaaaagcgac
      361 gtacaaattg ctaagattat agaattagaa gaagaagacg cagtgttgac aattgaaaaa
      421 aaataaatgt ttgtatacca tatgattatt tcaatatgta tcctggaatt ggagatctcg
      481 tagagctata tcaagatgaa tcaaatatac ttgtcattca tcatgaaata tagagactta
      541 taaaattgtt tatttttata atgtatcagt atagaaagga aataaaacat ggattatact
      601 gttgaatttg acagtgaact acttaagcaa tttccacaag aagaacattt catgtataaa
      661 gaagcaattt cccacaaagt gacagagtat ttggagcata atttttttcg tataaagcca
      721 gtgcgtactc gttcggcaaa aggaatatac gagatgaaag tcaaaattaa taaaaaaaat
      781 tatcgcatag catttgcttt aaaaaaaaat catgtgttca ttttttatat tagttcgaat
      841 ttgcaaaaaa ttgtatttga taaagaggtg agtaaaaaaa taaaatagct gagcattgga
      901 ggatagattg agtgatacta agtctatcct cttgtttttc taaagaacta agctagaatt
      961 ttttcttttg tacgttatta tatgttattt gtcattacca aaaagcacct tttttcttct
     1021 agtatctatg acataagaaa taccacccat ttcctttact tgaacaaatc ctactgattc
     1081 ataaaatttt tttgttttct cagtatcatc tgtcaataat tcgatttgga ctggtccata
     1141 actagtgatc ttctccaaag cttcattcaa aagcactttg cctattcctt ggcgctgata
     1201 cctcggatga atgaggatat cttgaataaa tgcgatcgtc gcaaaatcag tgatccaacg
     1261 aacgattccg ataatcttcc cttccccatt acgctttatc agagattcag attgttcaaa
     1321 tgctctagct aaccttgcag tgtcttttgt gtaattcgtc caaccaacgc tcttatataa
     1381 ttcagaaatc tcatcgatca taagggaatc aatattcatt tttttcttcc tttcttatac
     1441 aattctccct ctaataatac agttctttga ctatttaatc tatcacatat aactctcctg
     1501 taaagattct ctcgattcct taaaattcct ctttcctttt agaatgcata ctttttgata
     1561 aataaaaagg ttgtgataaa ttttcttcac aacctctgtt tctctctatc aagtgttatc
     1621 ttttaatttt ctacccttac cctagcatct ctattgcccg tagtatgcat actttccatg
     1681 tttgcgaaaa taatgtttat ctagtaaata ttgcgggatt tcacatatat tggggttgat
     1741 cagctcgttt tctttggcca tcagacaaat ttcatctaag atcaaactgt tttctactgc
     1801 tttcataggt gaatcccccc atgtgaacgg tccatgtcca tagacaagta ctccagggac
     1861 ttcgtttgga tctaattttc tttccttaaa cgtctcgaca atcacattcc ctgtatgaac
     1921 ttcgtaagct tctcttactt cttctttcgt taattggcgt gtacaaggaa ccttaccata
     1981 aaaagcatca gcatgagtcg tgccataagc tggcaaatcg cgtcctgctt gcgcccacat
     2041 gacggagtgc gtggaatgag tatgagtaat agcagttata tcttcaaaag tttgatacaa
     2101 aacaacatgt gtggggagat ctgaagatgg ttttaagcta tcttcttcta ttatatttcc
     2161 cgacaaatct gttaccacca tttgatctgc ttgcatgcat tcatatctga caccgcttgg
     2221 cttaatgacg atgactccta gctcacggtc cacttcactc acattgcccc aagtcaattt
     2281 gactaatccg tatcgcggca atgccagatt tgcttcaagg acacgttgct tcattgctgc
     2341 aattttttct tcacaagaca tcatagccag cctccttcaa tttagaactt aagtagtctt
     2401 ttgcctgctg gatttctctt cgaaagtctt ggcttttttc actccacatt tcaatcagaa
     2461 atgttccatc ataatctaga cgtttcaaat gtcttaataa tccaagaaaa tcaacacaac
     2521 cgctaccaaa aggaacatca cgaaactggc ctgaatattc ttttgttaca gggtaagtat
     2581 cttttaagtg gatagcagtg atataatcga tccctttctc aagttctcga gccggattat
     2641 tttccggcca tgcggacaaa ttgcctaggt ctggatatac ttgtagaaaa ggtgaatgaa
     2701 tctgttcttt gatttctaaa aattttgaaa tggagttcat aaatggatca tccatgattt
     2761 ccacggaaag aatgatgcca tatttagaag cttcctttac gctttctttt attccttcga
     2821 taaagtcttc tctggaattc attgatttct cttcataata aacatcgtat ccagctattt
     2881 ggattacttt gacgcttaga ttatgcgcca aatggattgc ttttttcatt agttgtttcg
     2941 ctgctttttt cttttctgga tcagcagaac caaacggaaa tcgccgatgc gcacttaaac
     3001 aaatcgaatg gatacgtaca ccggagctga acatctcttc tctcagctca gctatctttt
     3061 cttcagacca atctaatcgt gctaaccgct catccgtctc atcaatcgac atctcgataa
     3121 aatcgaagtc catttctttt acaagggaaa aacgttcttt ccatgaaata tctttgggta
     3181 acgctttttc ataaatccca atttgagcca tttccttacc cccagatacg aatgatctca
     3241 tctttgaagt tttgtgcggc cttcatcgga tcatttgctg ctgtaatacc acgaccagtg
     3301 ataaaggtat acacatcgat cccttcaaat aagtgtaatg tgtgtggatt taatccacca
     3361 gttacagaaa cattaaagcc tagttcaatc agttttttga tcttcgataa atctttttca
     3421 ccccaagttt caccagataa cagcgcatca cggctttgat ggtagattac ctgccggata
     3481 ccgatgttat gccaatccat ggcttgttca aaagtccaat tgccgtagag ttctacttgc
     3541 aattcaccta tttctttttg tgctgcctcc atagttggaa tcgttgcaca acaaatgact
     3601 gtcatccagt ctgctcctgc ttttgcaaca ttactcgcca ctgttcctcc agcgtctgca
     3661 catttcgtat cagcgactag ttttttatct gggaacatac tgcgaataca gcgaatcgct
     3721 ttttgtcctt cctgtaagca aagaattgtg cccacttcaa taatatctac tacatcacca
     3781 actttcataa catctcctaa tgcatgttct aagtcattgt gatctaacgc aatttgcaaa
     3841 ttcggcctgc tcatcttagt tccttccttt acttgttttt ttggtaccac tttgtttcag
     3901 caaatttttc actgatttct ttgactgaca tcacattttt gataccgata actgtaactc
     3961 cttttttctc tgcctgagta aacatattca aaaaattgac tggcgtaaaa actacatcgt
     4021 attggccagc tgaacttttt ccctctgaaa tggcacaatg atggattttg gtaattggta
     4081 cgtttagttc tttcattgct ttttccacac ttctcatcat catcaagctt gttcctgatc
     4141 catttgcaca cgatactaaa attctcatct taatccctcc attatgagtg ttgtctaatc
     4201 agattttctt ttatactctc tgcttttctg catatgtgtc atagtcttct acaatcaaaa
     4261 aataaccatc aggatttttc cgatattgta actgcggaat agccaataaa ccaatgacaa
     4321 ctacggcaat tccagcataa cctaggactt tcatgattac tgtaaacaat ggccaagctg
     4381 ttgcccagtc gaacatcccg atataaccac cgtatgttga catcccaatc catgtagcga
     4441 ataatgctga accgcctact tgtatgattc ctgaaagaaa cgggaacagg caagcggctt
     4501 tgaatccacc tcggttattg gcataaactg ctataacggc attatcaaag aacaacggaa
     4561 tgaaaccggc tatgacgatc gttggtgatt tcaataaaat cagtaaacca atcatcaaaa
     4621 actgtcccaa agcaccaaac aagaacccaa tcgttaccgc atttggcgaa ccaaagccaa
     4681 aagtagcagc tacgtcaatt cctggaacag ctcctggtaa aatcgtgttt gagattcctt
     4741 ggaaagattg agttagttca tcgacgaatg tccgaacacc taattgcaag atcgccagat
     4801 ataccgcaaa atttaaagaa gtcgtcataa tgtagaataa gaaactctgc ccttcttgca
     4861 tgaattgcgc ttgaatcaaa taatctttgc ctagtacaat cagaatgatc ccaaagaaaa
     4921 atagcatgag taacgaagta gcaaccatat tctcattgaa aatcgacaag aatcctggta
     4981 atttgatatc ttcaattttt ttgtcttgct tgattgatct atttttcttt tcatcccgct
     5041 ttttcatcca ctcagctaat tttgcaaata taaagattcc gaacatttgc tgatgtgcca
     5101 ctgcaaatcc ggcaccttct gtcaattcct gcgtgattcc tactgttaag ttagaagcta
     5161 ctgtccaata acaacctaaa atcagtccca taaaaatcaa tgcttgtatc ctacctagat
     5221 caggaaagca aaacagtaaa atccaaaaag cggtagctgc ttgttgaacc tgaacgtttc
     5281 cggtagtgaa aacggaacgc agtttcgtat atttctgaaa acggactaat aagatattta
     5341 aaacaaatgc aatcagtaat aaaatcatca catctccaaa ggtacggcca aatgtctcca
     5401 ttaatccagc atccacagca ttttgtccaa aataaggatc tgtaaccatg gcatccaaat
     5461 tgaaccgttc ctttagtcca accaagattg gccgaaaatt attgaccaaa ccaccagagc
     5521 caacagtcaa aataaagtaa ccgaccgttg cctttaagaa tccagcgatg cattcatgaa
     5581 gcgggcgttt cagcaaaata tagcctaata acacgataaa accaatcagg tatgctggct
     5641 gcgtcaagat atttgttgca aaatacgtcc aaatgcttaa caaaaattcc cccatctttt
     5701 ttctcctcta tcaattaatt atattctgcc atcacaactt ggtaatcatc gatggagttc
     5761 gtagagatga gacgctcaac caatccatct gtcattaata attcggataa tttttggata
     5821 ttttctagat gttcttctgg atcttttgct gcgagtgtaa aaaacaaact agccgttttc
     5881 tcctcattct ccccttcact ttcaaaacgg attggctgtt tcaacttggt aaatgaaata
     5941 gctgttccaa aaacaccatc acttttttct gaagaatgcg gcattgctac ttgaggtgcg
     6001 atcacaatat aaggaccgta tttttctaca caatggatga tctcctccac atacgtttca
     6061 tcaataattt ccttatcgat caatacaaga cagctttcgg cgatagcttc acgccaatcc
     6121 gtgatttctt tatctgggta atgaatcaat tgatggtcaa aaaagtattt cagcaagaaa
     6181 ctccccttct ttcttataaa aacgacggaa acggtgtatc attttcaatc gagaagacat
     6241 cttcaaatcc tcgataaaaa ttaaactcaa gatcatcttt gtttgtcgga tagatgaatt
     6301 tcccgcctac ttgccagata taaggtttaa atccatactt caggcgatcc tttttgaatt
     6361 tccaaatttc agtgatctct tttggatcag ccataaaatt agaccaaata tcgtagtgga
     6421 caggaatcac tacttttgca ttcaatgact ccgccatgcg cagcatatca acagaagtaa
     6481 ctttgtctgt tatccctcgt gggttttcac cataggcccc taaacagaca tcgattttgt
     6541 gttcattacc atgtttggca aataaattgg agtaatgtga atctcctgca tgataaagat
     6601 tccctcctga tgtttcgaat aaatagttta ctgcaatttg atccatctcc tgaggcattt
     6661 ttccttttaa tacctcttct ggatcttcac aagtgaccaa cgctgtccga tcaaacgctt
     6721 ctaaagctac tacattgatg tctttgattt tgactgcatc acctggcttt actgtaatcg
     6781 ttttttcttc aggaattccc catttttgcc acgtgcgaac cacttctttt ggcccaatga
     6841 atgttgcttc aggacaattt tgatgaactg ctgcggctgt atggatatct agatgatcgg
     6901 aatggatatg tgtaacgatt aaagcgtcta cattttttat cgcaaaagga tcgattacga
     6961 aaggctgagt acgtaaatta ggctgcatat tttgaacgcc actcatacgc atcatctgat
     7021 ggcctttttt catcatgcca ttcccatgac tacgttttcc cgtcccacac catagatcac
     7081 ataaaatatt cgttccttca tgacttttca gccaaattcc cgtacagccc agccaccaca
     7141 tagcaaaagt tccaggatcc actacttctg tttcgatttc ttcattcaag tatgtgcccc
     7201 actcaggaaa tgtttctact aaccactttt cttttgttac ttcattgaca gttttactca
     7261 tttgcttgct ccccccatat cgttgttcca acttacaagt aaatattaat gtgtatcagc
     7321 atccatgaaa acccttttat atgaccgttt gttttttata tgattttctt tcagtaatca
     7381 atgattgttt cagtataata aagacagata tgaatgttta aatgaacaac tagtcaaata
     7441 aatccatgga tcaagatgtc cctcaggagg caaaagtcat gaaaaactca cttgtcaata
     7501 ttgaaaaacg tcaaaaagaa attttggaac tgcttcagca gactgaacaa ctatcaactt
     7561 tcgaattagc tgaatccctt gatgtatcta ttagtacgat acgaagagat ttaaatttat
     7621 tagaagaaaa aaacgagatc atacgcaatt acggttattg ttcttataat tacaaaaacc
     7681 agactgattt tgatcaatct ggtcctgaaa ggattaaaca agcgattgcc agagaagcta
     7741 gtaaatacat taacgattat gatacgctgt ttatcaattc tagctcgact gcgttgaaaa
     7801 cactggattt tcttcaatct aaccatttga cagtcattac aaacaacgtg aaaatcaatt
     7861 actctccgca caaagataat tgtagttata ttttaactgg tggagagatg cgctttccaa
     7921 aagaagcact agtgggcgac atcgcattaa atacgatttc ttcagtcaat gcagacattt
     7981 gtatcattgg ctgtagcgga gtcgatgtag tacatggggt cacaacaaag atattaaatg
     8041 aatcaacgat caacgaaatg atggtcaaca agacaatcaa atgtaagatt ttagtcgctg
     8101 atcatcgaaa aatcggactg acatcaaagt tcaagattgc tgatatttca gtctttgatt
     8161 atttgatcac tgataaattt tgttctgaaa aagtattaga ggagatcaga aatacgggga
     8221 taaaaaccat tcaagtagat tcattttaag aaccaggacg taaatatgta aataggatta
     8281 tcaaaaaaat gaataacaaa tttatcgata aatgaaaaac acgctacgct caaattgata
     8341 aaggaatccc aagatgtatc catccaatcg ataccatcat aatctattgc ttcttttata
     8401 accgttatat gttgcctaaa taggaatcaa acaatatcga aaaaaggagg tatgacaaaa
     8461 gtcacacctc cttttttcga ataaacggta ttcaaatcag aacactgatt tcacaaccac
     8521 tttatttcag gtcgttttca atcaccttta ccgcgtaatc atttccgttg aaacgcgcta
     8581 ttttttttgc gtccatatat ctttctaaat aatcatcttc tcctaattgc ttatggcaag
     8641 aagcaatttc ataaagcaag tattccaatg cataagtcga tttatgtttc ttattatact
     8701 caataccctt ctcacataat tggattgctt tatcataatc ctcgatttta cggtaatagg
     8761 tggcgatatc ataatataca atgcagacca tcagattatc aaaatcagtc tcactcaata
     8821 ttttaagtgt acgctccaca taaactttcg caaaatctaa ttctcctttt gacaagtaga
     8881 tcattgccac gtttgcagct gcttgtaagt gatggatatc tgtttcggtc gtttgttcca
     8941 acacttgatt aaaataaaat aatgctgcat ctggtttttt cgcataaaga tgatcaagca
     9001 gtccttgata aaataaaatt tgatttaaaa gatcagaatt acttactttt tcctgatcga
     9061 tcgtttgtaa aattttataa gattcttggt attttgatac agaattcaat gattgaatct
     9121 catttatttt tttcctgatt ttgtcttctt ctgtttctac taatatatcg gagatctcga
     9181 cattcagctt tttgcaaagc gcacttaaga tattgatgcc tggcgacata ttcttgtttt
     9241 cgatattgct gacagttgct tgttcacaaa tgccttctgc taattgtact tgtgttaacc
     9301 cctttttctt tcggtattct tttagtaatg ctccatctac tttaatcaaa acaatttcct
     9361 tccctttaaa aaattatttc tcctttatat catacacaaa aaaaagttct aaacaaccaa
     9421 aaatgtttag aacagaataa aaattttaa
//
LOCUS       DAFLWQ010000102         8941 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.105, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000102 DAFLWQ010000000
VERSION     DAFLWQ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8941
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.105"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            78..896
                     /gene="purR"
                     /locus_tag="L1V16_002553"
     CDS             78..896
                     /gene="purR"
                     /locus_tag="L1V16_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBN1276839.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            1399..2772
                     /gene="glmU"
                     /locus_tag="L1V16_002554"
     CDS             1399..2772
                     /gene="glmU"
                     /locus_tag="L1V16_002554"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBN1276840.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            2866..3837
                     /locus_tag="L1V16_002555"
     CDS             2866..3837
                     /locus_tag="L1V16_002555"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBN1276841.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     regulatory      3843..3945
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            4011..4580
                     /gene="thiT"
                     /locus_tag="L1V16_002556"
     CDS             4011..4580
                     /gene="thiT"
                     /locus_tag="L1V16_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HBN1276842.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     gene            complement(4661..5434)
                     /locus_tag="L1V16_002557"
     CDS             complement(4661..5434)
                     /locus_tag="L1V16_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276843.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            5701..7381
                     /locus_tag="L1V16_002558"
                     /pseudo
     CDS             5701..7381
                     /locus_tag="L1V16_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
     gene            7351..7569
                     /locus_tag="L1V16_002559"
     CDS             7351..7569
                     /locus_tag="L1V16_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HBN1276844.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            7589..8479
                     /locus_tag="L1V16_002560"
     CDS             7589..8479
                     /locus_tag="L1V16_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBN1276845.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            8497..8781
                     /locus_tag="L1V16_002561"
     CDS             8497..8781
                     /locus_tag="L1V16_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276846.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
BASE COUNT         3017 a         1532 c         1882 g         2510 t
ORIGIN      
        1 tcataaaatg ctcgaatttt tgaagaaaaa cttatataat gtaaaacgat aaaatttctt
       61 aaaaggagtt ggaataggtg aaagtacgtc gcagtgaacg tctagttgac atgacacagt
      121 atttattgaa tcacccgcat gaattgattt ccttaacaag ctttgccgaa cgttatgaat
      181 ctgctaaatc ttctatcagt gaagatttgg gaatcatcaa gaaaacattt aaagaacgag
      241 ggtatggaac cttggaaaca atcccgggtg ctgcaggtgg tgtattgttc atccctgaaa
      301 tttcatatga agaggcgaaa aaatatattg aatctctagc agaacgtcta tcagaacaag
      361 accgtctgct tccaggagga tatgtttatc tctctgattt gttaggagaa cctgaactgc
      421 tgcgtcaagt tggaagaatc attgcttcta aataccttgg tgaaaaaatc gatgctgtaa
      481 tgactgtagc cacaaaaggc gtacctattg cccaagctgt gtcctattat ctgaatgcgc
      541 cattcgttat tgtacgccgg gactcaaaaa taacagaagg atcaacagta agtgtcaact
      601 atgtgtctgg atcttctgaa agaattgaaa agatggaact gtctaagaga agtttgaaac
      661 gtggttcacg tgtccttgta gtggatgatt tcatgaaagg cggcggaaca gtcaacggaa
      721 tgaagagctt gattgaagaa ttcgaatcag aacttgttgg catcactgta tttgccgaat
      781 caaaattcaa cggtcatcgc gccatcgatg attatacgtc actgctttat gtcaaagatg
      841 tagatactca aacgaaaaat attacggttg tgccaggaaa ttatttttca gaataagagg
      901 ttgtgaaaaa gctgcttagt ttcgagtagt aagaaaaatt ttgtgaaaat ggctttccac
      961 attttttcat aaatttggct taataccgag aaactggctt ttgaacaccg tttatctaga
     1021 ggttgtgaaa tcagcgtcct gtcctgagta ttagctcaat aaacggaaaa attgctcctc
     1081 atattttgcc gtttattgag ctaataccga aggtcagctg attgaaaaac gtttaatgaa
     1141 gaggttgtaa gcctaccgtt taactctaag tcacaagaaa cgatttcaaa aaacagcttt
     1201 tcatgtttta tgagtagtgt gacttgtgac cgaggagttg gcaggagagc accggttacc
     1261 aaatagatag gcccgttatg gtctatctat ttttttatcc agaaaacgct gggataaaag
     1321 aaaatcactt gttttgttga aaaaatgggt atactgggat aaactgaaat cagcaaacta
     1381 tatttaggag tgacgcagtt ggacgcacgt tatgcaatta ttttggcggc agggaaaggt
     1441 acccgcatga agtcaaaatt atataaagtt ttacatcccg tttctggtaa acctatggta
     1501 gaacatatca ttaatcgggt cagtgaaacg aaaccagatg aagtgattac gatcgttgga
     1561 cacggagcag aacaagttaa agcacaacta ggagaacgca gtaaatatgc gttacaagca
     1621 gaacaattgg gaacaggaca tgctgttttg caagctgctt ctttcttgga aggaaaaaaa
     1681 ggaacaacgt tagttatcag tggcgataca ccattattga ctactgaaac gctgaacaat
     1741 ctttttgaat atcaccaagg aaaaaatgca agtgcaacga tcttgacggc acaagcagaa
     1801 aacccaacag gatatggacg aatcatccgt gaccatattg ggatcgtaga aaaaatcgtg
     1861 gaacaaaaag atgcaacacc agaagaagct cttgtacaag aaatcaatac aggaacttac
     1921 tgttttgaca acgaagcttt gttcgatgcg ttaagcaaag ttggaacaaa caatgctcaa
     1981 ggtgaatact atctaacaga tatcatcgaa atcttaaaag aagaaggcca tacagttgct
     2041 gcttatcaaa cggatgattt tgaagaatca atgggagtca atgatcggat cgcgttagct
     2101 aaagcaaatg agatcatgag aaagcgaatt aaccagatgc atatggtcaa tggcgtaagc
     2161 tttgtcgatt cagcaacgac atacatcgat gcaggcgtag aaatcggtcc agacacattg
     2221 atcgaagcag gtgtacaaat ccaaggaaat acagtcattg gttctgattg tgtcatcggg
     2281 tcacattcaa aaatcgtaga cagtaggatt gaggatcacg tcgtcattga aaactcagtc
     2341 attgaaagca gccatgtcaa gaaacatgca gatgtgggac cttatgcaca tttacgacca
     2401 aaagctgaaa ttggcgaaaa cgtccatatc ggaaactttg tggaagtgaa aaatgctcaa
     2461 atcggcaaag gaactaaagt cggtcacttg acttatgttg gtgatgctac gctgggagaa
     2521 gaaatcaatg tcggatgtgg tgttgtcttc gtcaactatg atggaaagaa caaacatcat
     2581 acgactgtcg gcgaccacag ctttattggt tctagcacga atatcatcgg acctgtcgag
     2641 gtagctaaaa acagttcgat tgctgccggg tcaacaatta cagacaatat tccagaatat
     2701 gcgctggcaa ttgcgagagc aagacaagtc aataaagaag gatatgcaaa aaaactccct
     2761 tatctaaact aagacttttg caaaatcact tgatttattt aaaaaatatg actactattt
     2821 attaggtaga attctagagt tgtgaaaaag aaagtggagg tccccatgtc aaaacattac
     2881 tttgacccaa gattaaaaat ttttgcgtta aattccaatc gcccattagc agagaaaatt
     2941 gcagcagcag tcggcgtcga gttaggaaaa tcatctgtta ctcaatttag tgatggagaa
     3001 attcaagtaa acattgaaga aagtattcgt ggatcgcatg tctatgttat tcaatcaacg
     3061 agcagcccag tcaatgataa cttgatggag ttgctgatca tgattgacgc actgaaacga
     3121 gcaagtgcaa aaacaatcaa cgtagtcatg ccttattatg gctatgcgcg tcaagaccgt
     3181 aaagcacgtg cacgggaacc aatcacagcg aaattagtag caaacatgat tcaaaaagct
     3241 ggtgcaacaa gaatgctgac tttggacctt catgcagttc aaatccaagg tttctttgat
     3301 attccagtcg atcatttgat gggtgcgcca cttattgcca attatttctt agaaaaagga
     3361 atcaaaggcg atgatgttgt cgttgtttca ccagaccatg gtggtgtcac acgggcacgt
     3421 aaattagcgg aatttttgaa atctccgatt gcgatcatag acaaacgccg tccaaaagca
     3481 aatgttgcag aagtaatgaa tatcattgga caagtcaaag gcaaaacttg tgtactgatc
     3541 gatgatatga tcgatacagc aggtacgatc acattggctg ccaatgcttt gaaagaagct
     3601 ggtgcaacta gtgtgtatgc ttcatgtaca catccagtat tatccggccc tgctttacaa
     3661 agaatagaag attcagctat cgagcgtcta gttgttacag actcgatcta tcttccagaa
     3721 gatcgtaaaa tcgacaaaat cgatgaagta agtgttggcg gactaatggg agatgcaatc
     3781 aaacgtatcc atgaaaacaa accagttagt ccattgtttg aaacaaaaaa taaataataa
     3841 ataaactcac aaaggggagt ccaattgggc tgagattgaa tctatttcta aacccttcgt
     3901 acctgtatcg gttatgcgag cgtaggaatt gtgaataaac agctgtttga ctattttcga
     3961 aagctgcttc ctcctttgtg acttttttat tcaaaggagg aagttttttt atgggaaaaa
     4021 atagagtttg ggtagaagga acgattgttg cagcgttagc gatggtgttg tcgttgattc
     4081 cgatccagat cggcagcagt ttttctattt cattagggca gattccattg actctttttg
     4141 cgttaagaag agggacaaag gcagggatgc tggcaggttt catttggggc atcctacatt
     4201 ttccgttggg acaagtttat tatttaagtg tcgttcaagt gttgattgag tacccgattg
     4261 cctatacttt tgcaggcgca gcagggctca tggcttcaaa tgtccaaaaa ggctatgtag
     4321 acgataatac gaaacaaatt agaaaaagca tcgtgtttgg tgcattgatt ggcgcacttt
     4381 ccagatattt ttggcatttt attgcaggag tggttttctg gggagcgtat gcactatggg
     4441 ggatgaatcc ttggctcttt tctttcgtaa tgaatggtgc cagcgggttg agtacagcta
     4501 ttgtaacgat catcgtttta ttagggatcc aacaaacgac tccttcgatt tttgtgccag
     4561 ataaacgaca ggagctgtaa ataaaaaaga agcaagaaac ttgagacaga atcatgtcct
     4621 agtttcttgt ttccttttta ttttttgata agaaatagat ctacttcaat ggcagataag
     4681 aaagatcggc atcttctacc aattgccagt gtcgatcggt gacagagtag attaaagtag
     4741 cgatgatttc ctcttctcga taccgggtgc cttttaattt ccaaatataa tcttcaatca
     4801 catagattgg gatacgatat ttaccatcga tcaaaccaac ttgatcaaaa gaaaaaatga
     4861 tcccttcctg catcaaatta cgcatttctt tcaataattc cacactgatt ttttcaacag
     4921 gtgtttcttt tttgaaaaaa gattttttta cattgatctt atctgacaag atcgaactta
     4981 atttactagc aaaaatccta taaaattcat ctaaatagcg ataataaatc cgattcagct
     5041 gatcattaag atcgaagtat acaaaattat tctgtagttt ataaaaaaac ggcgaatgaa
     5101 gatgtgtttt catatgacca aaatataata attctgaaat ttctaaaggt gtcaattctt
     5161 tcagcatcgt taaatcagta aagtcgatcc acttcaattc atcgaatcca cgcctgttac
     5221 gagaagagga aaagaaacgc tgaatatttt ctgtaccacg gattactttc agccctgtat
     5281 gggattcata ttctccagca gaagcagatg gatcaagcaa gagcaagttt tgaggaaaat
     5341 gcacgatact gtttgcaaag tcagtagcag tcagcccttt tgttaaaaca gcattacttg
     5401 tggtatcaat atgtacataa actgactcag tcatcatgtt cctcctctta tttcctctta
     5461 atctctttta ttttacaaca tttgcattaa aaaagcttgt ttcttttatt ttaaaattcc
     5521 attacaaaat cacgttttca ttgaaaacac tctcattttc aattaatttt tgtgattttt
     5581 gtattttttt atttaaagga ggttttatga attgttttct tatggaatct acaaagtcga
     5641 atacgagact catgaccttt ttatgacgta ctggtatact tgaagaaaaa ggagagcgcg
     5701 atggagataa aaaaagttta cttttcacag aaaatgtcgc tgtattcgcc tatccagcaa
     5761 gcaaaacaac cccttccatt ttttcaaagt catcaagaaa gtagagacgc tttttggcgt
     5821 tctgcaaaaa agcaatgtgc ttttaaagca gtatcgaaaa aatataccgt ctattttact
     5881 attgctaaaa gtagaggaga tgttattttt aataatctgt tgattgaagg tgaaactttt
     5941 gaatggaaaa aattttttcg gtatatggaa gcttgcgctc gtttttttat taaagaaaac
     6001 tgttgttttt tatttcaatc tcctctatca gaagaatggt tgcgtatttt tcataaaaac
     6061 ggctatcaag gaaccacaca attaaataaa aagctggtct atcatacagc acttgtttta
     6121 ggtggaggag gagcgcacgg tgcttatcag attggtgtgt ggcaggcgct gaaggaacat
     6181 gatatcaact ttgagattat cacaggtacc tcggtaggtg cgttgaacgg cgcattgatt
     6241 ttacaaggag atatgaaaaa agctgtcgac aagacaagtg cttgcgttac cagaaatggc
     6301 tgcagttgaa gaccttcgtg aacgcttcta tcgagaaaga cgccaaatga cgaaaacagc
     6361 actaattgaa ggcggggttt cttctgctcc attggaaaag atggtcaaag acaatttgga
     6421 tttgtcctta ctcaaacata atcccaaaat acgtttatat acggtgtcta ctaaactgcc
     6481 agaactagcg gaagtagtga ctgatatcca acagacaaaa acagaagaaa taccagattg
     6541 gatactcgcc tctgcttcat tttatcccgc tatggcttat cgaaagatcg gaaaaaataa
     6601 atatgcagac ggtgggtatc gcaacaaaat acctattgat attgcgatta acaaaggagc
     6661 aacagaggca tttgtcgtag atgtgcaagg gccaggccca gcgaaaaaaa ttcgtatgcc
     6721 agacattttt atccattgga aatgtcaaac attgtggaca ctaggcagct ttctgctttt
     6781 tgatagccaa aggaaccaat taaatttaca attaggctat ctggaaatga aaaaacgatt
     6841 aggctattac tatgggaact ggtatacatt tcattctgtt aaacctgcaa gaacatactg
     6901 gcgaggattt ttgtcttact taacaaaaga aattcagtta gaattatctt ttttcaaaag
     6961 cataaaattt tggcaaaaac tgcgtaattt atataagaac agggtcgtac cagagacatg
     7021 cggattggcg atgctagaac ttttagcaaa aaaacatttt ttactgccca atgaaatcta
     7081 tcaagtagac atgatgattc aaatgatctg ccaacaagat ataaaaagta tgccggatga
     7141 tttattggca caaattggtc aattaagtac tgaagaatgg cgaaggtatc gaaaatacca
     7201 gcaaaaaata caaaatgagc gcacgaaaac tgtttatttt gattatctgc tacaaggaaa
     7261 acgcaaggat cgtttgcagc atgaattgct taagcaacca gttgacacat tactgatcct
     7321 atatttatat tatctcaagg aggaacaacc atggcacaag aattttcata tgaaatcgta
     7381 gaagaaatcg ctatattgtc agaaaacaac aaggggtggc gtaaagaact gaacctagtc
     7441 agctggaatg gtcgcccgcc aaaattcgat cttcgagatt gggcgccaga ccatgaaaaa
     7501 atggggaaag gcctgacatt gacgaacgaa gagtttgaac aactgcaaaa agcaatagaa
     7561 aatatgtaat gaggaaggac cctgtcgaat gaaaagtatg actggttttg gcaaagccat
     7621 ccgcgaaaca aaagcgtatc agttagatat tgaaataaaa agtgtcaacc agcgttttct
     7681 agatgttcaa atacgaagtc ctaaaatcct gaactttgtt gaaaacgatt ttcgtcagct
     7741 tattaaacag cagttaagcc gcggtcgaat cgaagtattt gtgaatctag cttatattgg
     7801 caaaaacgaa aaacagatcg tcatcaactg ggaattgatt gattcactta tcactcaatt
     7861 gacagacgga attcaacaac gatacggtag tcaaaatcaa gtgtcaatta gtcggatggc
     7921 ggaacgcttc gcgctggacg aaaacttcgt aacggtagaa gaaaaaccgg aagagagcat
     7981 ggaagaattg gcacagttag ctctagatac attgaaaagc gcacttgatt ctattgaggc
     8041 gagtcgagaa aaagaaggtc aagctttagc tttagtgttg aaaaagaata ctgaagaatt
     8101 caaagaagta ctaaaaaaac tcgatagttt tgtagaaatc tatgaaaagg aatttcaaat
     8161 aaggtatcaa aaaaagctgg aggaatttct tggagcgaaa gtcgatgagc aacggttgtt
     8221 gacggagcta gccatcttgt tggaacgcgg agatattcac gaggaactgg atcgtctggc
     8281 gatccatgta caaaaactag atgaacttat cgaagcacaa tgtcctgtag gtcgggaatt
     8341 agatttcctg atccaagaaa tgaatcggga aatcaacacg atcggttcca aatcaaatgc
     8401 aatcgaaatt aaaaatcaag tcgtccagtc taagacgatc ttagaaaaaa tcagagaaca
     8461 agtacaaaat attgaatgac gaaagaggta gagataatga aatattatga cgtaacgttc
     8521 cacgaattaa gtggaaaaac tgtggttaaa cgggatatcc cttctgaaaa aaacggcttt
     8581 gacgtatgga aagatgcctg tgcagactat aatgagaacg aactgtttat tttgatcaac
     8641 gacggtgctt acgtgacgat gaatcggaaa tttattgttc gaattgacac agaagaggta
     8701 gaagatccga cagaaaaagc acgttctcga aaagatgaga tcatgggtgt agtgaatact
     8761 ttgtccaata tgggctttta gcaaggatgc tgaacaaaga aatacaataa ataatcagaa
     8821 ttggatttct tcgcttagct tctttgctct aggaatacat ttaaaggttg tgacaaaatt
     8881 cgtgtcacaa tcttttttta ttttgaataa gtgatgttca aaaaccattt tctcggtatt
     8941 a
//
LOCUS       DAFLWQ010000103         8539 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.106, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000103 DAFLWQ010000000
VERSION     DAFLWQ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8539
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.106"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..888
                     /locus_tag="L1V16_002562"
     CDS             <1..888
                     /locus_tag="L1V16_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HBN1276847.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
     gene            complement(928..1620)
                     /locus_tag="L1V16_002563"
     CDS             complement(928..1620)
                     /locus_tag="L1V16_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1276848.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(2057..2626)
                     /locus_tag="L1V16_002564"
     CDS             complement(2057..2626)
                     /locus_tag="L1V16_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBN1276849.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(2700..3023)
                     /locus_tag="L1V16_002565"
     CDS             complement(2700..3023)
                     /locus_tag="L1V16_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276850.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(3177..3989)
                     /locus_tag="L1V16_002566"
     CDS             complement(3177..3989)
                     /locus_tag="L1V16_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276851.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            4343..5191
                     /locus_tag="L1V16_002567"
     CDS             4343..5191
                     /locus_tag="L1V16_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBN1276852.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            5336..6277
                     /locus_tag="L1V16_002568"
     CDS             5336..6277
                     /locus_tag="L1V16_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HBN1276853.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFSHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            6267..8438
                     /locus_tag="L1V16_002569"
                     /pseudo
     CDS             6267..8438
                     /locus_tag="L1V16_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2664 a         1633 c         1521 g         2721 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 ttaaatggac tatctccagt agaatatcgg aaacagtcca ttaaatagtt caacttttgg
      901 ggttcagttc aaagaggggg ggatttttta tcgttgtgga atatttaaat accaacgctt
      961 gtcatgaaaa tcttgtgctc cacccttagt atttccttct ggatcgtttg tcgcacgcat
     1021 catgacgtat actttcttat tagggaaatc acgcatattg aaagatacat gatagccaac
     1081 atttcctaaa gtattataag cttgatttac gtctggtcta taaatcccat cagctcttac
     1141 tctagctagt tcttttccag tattgtagtc cataatgaaa atatactcgt atttataatt
     1201 agcaatgtgc catccagcta catgcaagtt tgcgttttcg atttctccga actgatcaat
     1261 gtgggcgtaa tttgttccat ctgtcagcgt agaatttgca gcacctgctc gagttggatc
     1321 aattactggt ttatcctccg aagtagttgg attatcatcc gtaaaaccat gagccaaatc
     1381 ataggctagt ttttctttac ttacacctat ttcagaaaga taaccgtaag gatctgtatg
     1441 atcgccccaa atattttgtg ttacccataa atgcgatttg attcctggtt ggttataagg
     1501 agtgtctaat gttaatggaa taccatattt cattgctgaa tctcttgcca attcaacgta
     1561 tactttatag ttcttttcaa aagtttcttt atcatgtgtg tgttgtaact cgatttgcac
     1621 aggacttttg gctcacgagg ttgtcctact ctacatcttg ctgatagata tgctgaaagg
     1681 aaaacaccaa cattatgttt tgctttttca gctagaacga gacaagcagg aataccttta
     1741 gaagatatca aaggtttttt aggtcataaa gatgtttcca ctacacaagt ctatgcccat
     1801 atttctcccg aagtgaaaaa aagatcaatg aatcaactag aaaactatat agaagagcaa
     1861 ataaaaaagc actcaaattg agtgcttttt taagctcact atcactaaaa ctatcactaa
     1921 ttttatttat aagcgaacat gtttctatca ctgatttttt aaatctagcg aaaaaccctt
     1981 atcttaaagg cgttcgttca attctttggc aaggtcttca aagcctggct tgcctagaag
     2041 tgcgaacatg gttttcttat agctcatgta gaaaaatttt cttgatgatg attttatcca
     2101 tcaattgaga ttgactgttt tgctctccta tgatttcagc tatgattgtc cgattttgcg
     2161 gttttcttct taactggtag ttgattttcc cagtttccat caactcgcta agcatatcca
     2221 cgactccgcc aaatccggtc tttttcgtaa taaaacctag tgctaccatt cgttcatcta
     2281 gattttttgc tgtaatcgtc acaccagtaa tgagcgagtg ctgtaatgtt tgggccagct
     2341 cttccatccc ttcagcattg gatacgacgg aagctgtttt gttaataggt tcttcgttta
     2401 tttcttttgg ttctttcctc tccactttca ctgtttgacg aaggacatct agttcttgca
     2461 agagcgtttc gtattgttct tgggtcagca tcacgccagc tactttttca cgattaaata
     2521 tatatacgcc agttcccgcg tctcgcgctt gagcaaatac atccatcggc gatcgtttca
     2581 cttctgtgat cgaagatgtg ggaacttcta atttctttaa ttccaatgga tttcctcctt
     2641 tactaatcgc tttttattat agcacagact gacttgtttt gatctttttt ccaaaggttt
     2701 tatcggtttt tgcctaacca gtaattgata tcggtaagaa gtctttcgat accaaatgaa
     2761 ggatggtaca gatacgtttt ttgatcttcg ttatggtcta gtggaaaaaa atgatcgatg
     2821 atcactagat ctgcataccg aggcggctta tttcgagtac atacatgtat agagatccgt
     2881 tttcgatgtc ttagcgtttt gttcagtacc ccagcaagtc ttcttgcttc ttggtgttca
     2941 tagcgaaaaa aaaagacgat tttcacttca ggagggtgga catctaaata ccctcgttcc
     3001 tggagtgttt tcagtaaaag catcccccac tctactgcgg ggtgtgcaag tgcttgttgg
     3061 atcgctagcc gaaattgata tagtttatct ttggaattgg gaaatttttc taatgtttcc
     3121 tgataataac gaacttcttc tatcagccgg tcatggatac caattacgta acgaagtcat
     3181 tcttggtaaa gtacttttgt cagctttgat ttgctttcgc tctcaaattc gctattcagc
     3241 caaaacagcg aatcaagctt ttcagtcaca atcgtcaatt tccgatagtc ttgtgtctct
     3301 tctatccgtt tccaccgctt ttcagtaatc tggttacagc tcaagcgcaa aattgctaga
     3361 taattttttt cttttattgg caaaatctgc tcctctctaa atagcaattc aggaaacaat
     3421 tcaaagaata gtgttcgact gtctcctaaa atctcgattt ctgccggatc ctttctttgc
     3481 ttcaataatt ggatgaacat ctcagaaaag gactgctctc catcatctgc aaaaaaatgc
     3541 ggaaaatctt tcaaaaagca aaacagcaga tatcttactt ttctttctga accaaagatc
     3601 tgtgcttttt tataagaaaa agaaaggtgg tactcgccaa accactttct caatcgctct
     3661 tgcgtagaac gatcgtactt ctgctcgtaa ggttcattca atagcagatt tttcagtaaa
     3721 caaaacgggg gtgattggat cagaaaaaca aacaagagat aaggttcgct atatccttga
     3781 tcataaacta actgaacggt tttcttatga agaatcagct gaatgggaca gtcgctttcc
     3841 gccaaacgtt tcagatgccg atccactgtt ttaacatcga ttttcagttc ttcagctaaa
     3901 tcagcttttc gccagatcaa atctttcatt agattgatta gtgaaaataa attctgtgca
     3961 ttttttgata atagtttttg ccatctcatc gatcatttct cacctgattt ctaaacatat
     4021 tgtttgatca aaatgggttc actcctaaaa agataaaaaa ctccctttct atttatttaa
     4081 atacgcaaat cttcctcatt attttttatt ttactcaatt taatcgtatt ctcatttcaa
     4141 aacgaatgta ctttaaaaaa acataataag atcactttgc ttgtaggatg tattcccttc
     4201 cattacaatg aaataaatag cgattttatg agaaggtgat gtgaaaatgg aagaaaaaat
     4261 agaagaatcc aaacaaaaaa tcgatcagtt gatataagaa ttagaaaaag cggtcatcgg
     4321 caaacgttca actatccaat tgatgatcgt ggccctatta gcaggtggtc atgtcttatt
     4381 cgaagatatt cccggtgtag gtaaaacgtt actggtcaaa gcactagcaa aagctgtaca
     4441 gggaaccttc agcagagtcc aatgtactcc tgatctgctg cctagtgata ttcttggttt
     4501 ttccgtatac aattcacaat caaaagagtt tgaatttcgt ccgggaccga tctttaccac
     4561 gatcttgtta gcagatgaga tcaatcgtac gactcctcgt actcagtcag cacttttaga
     4621 agcaatggcc gagaatcatg caacgatcga caacaataca taccctctag acaatcattt
     4681 ttttgtctta gctacgcaaa atccaatcga gtacgaagga acatatcctt tgccggaagc
     4741 acagctcgat cgttttttat tccgactaca aatcggttat ccttcttttg atgacgaact
     4801 tttgctactt ttggataaat tcgaaaaagt gttggataac ttaaatgaag tattgaacag
     4861 ttatgaaata gaagaaataa aaacaaatgt ggcgaatgtc tttgtcagtc ccgaagtggc
     4921 atcttatgcc ttgcagttag tgtcagcaac aagaagtcat gctgccatcc agcttggcat
     4981 cagtccacga ggaagccttt cctttattca ggcagcaaaa gcttatgctt taatccatgg
     5041 gagaaattac gtcacgccca aagatttgca ggatttagtt ccttacgtgt tttcccatcg
     5101 cctgattttt tacgatcgtt cattgaagga agacgaaaag aaacaaatca ttcatactct
     5161 tgttgcacaa attcctattc ctgtgaggta gattgaggta gacaatggaa aaaatcaaag
     5221 attatttcat taattttgtg ttatttctgg tatatttcat cattgtgctt tttgctcttg
     5281 tattcaacaa ttctttaggc tggttcttgt tggccttttt tactctttat gtatcatgga
     5341 gcttgatttc attaagcagc tttctaaaga aactttcggt tacttgtaca ttgcagccac
     5401 tcgtttatcg caaaaaaagt atgcaggtta tttttcccat agcaaaaaag agaacttttt
     5461 ctttacctct ccctcgttta caaatcggct tcccagcaat ctttgcagaa aaaaacaaga
     5521 gattttgatt cttacaaata aaccgcaaga agtccaattg ctttggcagc caaaagaaag
     5581 aggatgccat gaaacattaa ctgtcatttt tacagcctat gatagtctag gacttttcag
     5641 aaaaagtgca aaaagagaga tctcttttcc tgtgactgtt ctgcctgctt tttgtaagat
     5701 tcaagcagaa aaattacaga gagttctgga aaaaaaacag cagctgaacg cgtaccaaag
     5761 aggtcttgat tttcgggaac atcgcgctta tcgtccaggt gattctttca accgaatcga
     5821 ttggaaattg tctgctcata ctcaagagtg gttataccgt gaatacgatt atcaagaaga
     5881 agaatgttct cctctttttt gcttttgggg ttcgcccagt ccaaaatttg aacctctgct
     5941 agacttgtat ttttctttat ggcatttgag aaaagaaaag cagccggaac ttctgatatt
     6001 aggcaaccgc gcctttcatg gcaaagaccc cggtcatacc tattttgctt ctttggaagc
     6061 tggcgatgag aaaacttttt tcgcacactt gaaaaaatat gcaaaaaaac aaatcgtcct
     6121 ctttgttcct gagaattctc ctgaagtctc agaagctatt gaaacattgt caaaagatcg
     6181 aacggtttat cttgtttatt tcgtagaaaa acaactcatg gtccaagaaa aagacaagat
     6241 atgttcattg ccaggaggtg aatggattga cgattaaacg ggaaaaatgg ctgcgtggcg
     6301 tttactcctt tgtgatacta agtgtaggtg ctccgatatt tgtagtagct aatcaattgc
     6361 aaaacagcta ccttcttatc ctaactattg gtgtcctatg ccttattgtc tgctgtattc
     6421 ctaaaaaatg ggtacgtttg ctgctttctt tgccagtaat gataggttgt ttgtttttat
     6481 attttccttc gaagacattt tccatattat ggatcttaca gtttttttcg tcagttacag
     6541 aggaattctt ccatctatcc caaggtaaac tttattattt gccagaaaag acagcttttt
     6601 ttctcataat gttgctgatc tatttattta ttacattgac cgtggattac gactattggt
     6661 acgcaccctt tctttctttg atggcttact tcatgatgct taccgttttt cggaaaaaag
     6721 atttactgta cgaaatgatt gcggtagtaa ctgttttgtt cgtgtatctg gcagcaaggc
     6781 aatttttctc catccggttg ttgtcgagaa acactcgatt ccagtcattg actacagttc
     6841 tgcttatttg tttcttaact tttagcgcta tcttgccttt atatcttccg aaagtacacc
     6901 aatctctcga ggaaacgagt gaaccgatcc gagaatatct taatgatgaa gggctttatg
     6961 acacactcca tgagtatcaa ttaaccggaa gtgcaagaac aggcttcagt gagaatgatg
     7021 aacagcttgg tggaccttta tatgataatg gcgaagttgt ttttacagcg aaccaaaaag
     7081 gaaatggcta ttggaagatc gaaaataaaa atcattacac cggttctgga tgaatagaag
     7141 atcaggacgc acccatccaa ccaatccaag aattccctgt tgacatcacg agctaccaaa
     7201 ccgttataga agacaaagaa aacattacat tgaccctaaa aaaacaagct ttcttacctt
     7261 atccttatgg aaatactacc ttgactgatt tttcattagc tagtggacaa acgctttact
     7321 atttgcctga aagccagcga ttcattcctg tcccgaatga atcgacacgt tctgcaactt
     7381 tacaaacaga aaggttagtt tttacgagag aagaattaaa aagcagtcag ttaaaagctg
     7441 atgatttaga aaatcagcag acaaatcttc aattgccaaa aagtttgcct aaacgtattg
     7501 aggacttggc ggtcgaattg accaaaaatg aagcaacttt aattcgtaaa gtcgaagctg
     7561 tctaacagta tttaaaaaca agcggaaatt tccgctattc caaaacggat accgggcata
     7621 ctccaaaaga acacgattat gtggattatt tcctctttga ttcaaaagtc ggctattgtg
     7681 acaacttttc aacttctatg gtcgtccttc ttcgaacact tggtatccca gctcgctgga
     7741 caaaaggttt tacaaatggg ctcagaacag gcacagataa tcaagggaat gaggaataca
     7801 gcattctcaa tagtcatgct cattcttggc cagaggtata ctttcctgga tttggctggc
     7861 ttccatttga accaacccct tcatttgcca atccaatggg ttcacaacca gttgctgaaa
     7921 caaccgaaac cgtccagcct gctatcgaac aaccaaatga aagcgaaaat atggcagaaa
     7981 ctatttccag tgagagatct gaggtcattc catcagaaga aacaacactc acaccagctt
     8041 ataaaatcgt cttattcagc cttggagtgt gtttatccgt cttgttgttc tttctattgt
     8101 tattcagaaa atctctgcgc tggacaagtt atcttatcta tcttcatttt tttgcttcta
     8161 ctaatacgat tgcatatcaa aaacttctta accctttgga aacattggta ccgcgcaaac
     8221 ccgcagaatc tttgcaggaa tatagcctgc gaatagaaca agaattcaag ctagatctgc
     8281 gtttcattcg attaactact caatatgaag cagaaatata tggacgacaa gcagatccgg
     8341 taaaattcga taaaaaaacc tatttagaaa taacgcatat aataagaaaa acggtataca
     8401 aaaaaattct gacaaaaggg agccgcttca aaaaataaga taaaatttct ggagaatcta
     8461 cttctcgaat gccgagaacc agctgattga gtatcgatta ctcgaaaaaa aggttgtgac
     8521 acgttttttg tcacaacct
//
LOCUS       DAFLWQ010000104         8347 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.107, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000104 DAFLWQ010000000
VERSION     DAFLWQ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.107"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(423..596)
                     /locus_tag="L1V16_002570"
     CDS             complement(423..596)
                     /locus_tag="L1V16_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276854.1"
                     /translation="MSMLVRKLPLSVREFLFYLVCLIASGFKLIEHIFIFAYVLAMIA
                     FLSGGWLIIYLLS"
     gene            complement(599..997)
                     /locus_tag="L1V16_002571"
     CDS             complement(599..997)
                     /locus_tag="L1V16_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276855.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KIAVEKYFDSLEESAKEIFNGEKAGSYELDGIRFSLIPTTENIIPKKLYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
     gene            1213..2268
                     /locus_tag="L1V16_002572"
     CDS             1213..2268
                     /locus_tag="L1V16_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HBN1276856.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQNI
                     LSFSLANLARLEDQSDDVLTANLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDETLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            2288..2641
                     /locus_tag="L1V16_002573"
     CDS             2288..2641
                     /locus_tag="L1V16_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276857.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKNKPTDHNPIQQEHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(2823..3119)
                     /locus_tag="L1V16_002574"
     CDS             complement(2823..3119)
                     /locus_tag="L1V16_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276858.1"
                     /translation="MIEVKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAK
                     LKSDSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(3123..3941)
                     /locus_tag="L1V16_002575"
     CDS             complement(3123..3941)
                     /locus_tag="L1V16_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1276859.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAVNENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWMVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            4167..4388
                     /locus_tag="L1V16_002576"
     CDS             4167..4388
                     /locus_tag="L1V16_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HBN1276860.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKELMKEHEENDQSISHEDMLKELGL"
     gene            4390..4656
                     /locus_tag="L1V16_002577"
     CDS             4390..4656
                     /locus_tag="L1V16_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBN1276861.1"
                     /translation="MTYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            4769..5308
                     /locus_tag="L1V16_002578"
     CDS             4769..5308
                     /locus_tag="L1V16_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276862.1"
                     /translation="MYNISVNKLINFQKERFFMGWYGAYSSANEVIEEKKGYAKNGLE
                     IVDTKVTKTYGIILFKDAEGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFF
                     VGDQEKMVKQQLDRIKEENNKPNLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQ
                     DGSLTRFTRLSAGDVKEVA"
     gene            5802..6086
                     /locus_tag="L1V16_002579"
     CDS             5802..6086
                     /locus_tag="L1V16_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276863.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGVVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKNSFIGKLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            6360..6614
                     /locus_tag="L1V16_002580"
     CDS             6360..6614
                     /locus_tag="L1V16_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276864.1"
                     /translation="MNYTDEEQITLEYVFTNEKGEEIEKVLIISSKDLENALTYEPYE
                     STVTVNEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
     gene            6696..6881
                     /locus_tag="L1V16_002581"
     CDS             6696..6881
                     /locus_tag="L1V16_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HBN1276865.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            6948..7343
                     /locus_tag="L1V16_002582"
     CDS             6948..7343
                     /locus_tag="L1V16_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBN1276866.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEDLLEK"
     gene            7333..7710
                     /locus_tag="L1V16_002583"
     CDS             7333..7710
                     /locus_tag="L1V16_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276867.1"
                     /translation="MKSKKETEPMKSTHLNYFSRTLINNLLKDTTGISVSTKHFANDL
                     IIFEDNNLRIEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKK
                     AKLLFEFQTDYHNELLAQSEILD"
     gene            7732..8106
                     /locus_tag="L1V16_002584"
     CDS             7732..8106
                     /locus_tag="L1V16_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276868.1"
                     /translation="MKQTQTEPINDTLADQLAGYYKLFEMSKAQRLIHYLWKYKILFL
                     FWEATLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVISDAGIERN
                     IKRVSFKITLNKPTDKKLSEAF"
BASE COUNT         2928 a         1423 c         1329 g         2667 t
ORIGIN      
        1 aaaaagctaa atattttatt tttgttattt tattagcagg aaaatttaaa tagttttaca
       61 agaatccgta gaaatatatt ggttttgcct tcagattaat actggatcat attaatctga
      121 atataatata tgaactaata aatagcttaa cctcgctatt ttgttttttc tgatcactat
      181 ctatacagca ttagtaaata gaattttaaa aataaaaaaa ttaagacaaa aaagtatcaa
      241 cataaacata tacatataca cgtttatgtt gattcactta atttgtcctt taaaaagcac
      301 ttattttaat ataatgttat tttataatct tattacaagc tgattgttag gcgttgtcct
      361 ttcattacat ttattaacgg ttattttatt gtttaattta ttaattattt ttgatctaaa
      421 acttagctta acaaataaat aattaaccaa ccgccagata aaaatgcgat cattgctaat
      481 acataagcaa agataaaaat atgttcgatc agcttaaacc ctgatgcgat taagcagacc
      541 aagtaaaata gaaattctct tacagataat ggtaattttc taactagcat actcataatt
      601 aacaccccaa agtaatattg tattttgaac attttacatc caatacagca tcaatcaacc
      661 attgccaatc aaaaatacaa ggcttcattg aagtatgttt ttcagatgaa aagatataat
      721 ataatttctt cggaataata ttttcagttg ttgggatcaa gctaaatcta ataccgtcta
      781 actcatagct accagctttc tctccattaa aaatttcctt agcactttct tctaaagaat
      841 caaaatattt ttcgacagca atctttgaag cttttactat tgaagcattt cccttttcga
      901 taaaatctgc ttttgtttta ccgacaataa gtaattcttg atcagtaaaa tcttctaaaa
      961 taatggtagt gtaattctta tttcttctca atcgcatcag gatcactcct taatataatt
     1021 tatgttttta taatatcata ataagataaa tttgcaagca tttatttaca cctttttatt
     1081 tacactttat tataattaat tagactttta tgattgcatt tttttcttat aaacagttgc
     1141 aactaatagt aaataggtgt aaactatttt cgtaccgaaa taccataaac acaaacagaa
     1201 agaggtcata ccatgaaaga accattattg ttttccgttg acttagggaa taaatcagta
     1261 aaagaaatga gtacacacgt ttctccactc tcacttccct ctcgtatttt gaacaaaaat
     1321 atcattaatt caggacgttt ttctaatata ggttcctcat taaaacgatc actaaacgtt
     1381 tctgaatata gcctagtaaa cactactgaa agctattact ttgggaagga tatacacgag
     1441 ctaggaaaag atgactacgt gatagaatca ctaggttttg ggatcagcag atacaagcag
     1501 gaaacctacc aaaatatcct atctttctct ttagctaacc tagcacgttt agaagatcaa
     1561 tctgatgacg ttttaaccgc taatctagtt ttaggtctgc cttcatccga ctataccgaa
     1621 acaatcgtca aatacgtgat gcaacaagcc acacgacaac attcagttga agttgacggt
     1681 aaagcttata atataaacgt agataccgtt tgggtactgc cacagccgat tggaacacta
     1741 tataacctcc tacttgctga tgatggtagt gtacaagatg aaacattgat cagtcagaag
     1801 atcggttttg ttgatattgg cggtggcacg aaactttttg atgttgtcca aaattttgaa
     1861 attgacgaaa acaatcgtga acaaaaggat accggcattt ttactttata taatcgtatc
     1921 gtaaatatgc ttgaccttcc gatcagtcct aatgctttcc aacttgaaaa gattatccga
     1981 gaaggcaaag aaaaaggcgt atatctattt aagccaagcg gaaatgaaag ttttgatatt
     2041 tcagaagtag ttgaaagaga aataaaaaca tacaccaata tggttgttgc agaagtttta
     2101 gctacattca aaaacttcac aaccttagat aaagttgtct ttactggtgg tggagcttct
     2161 attatcgaca aacaacttgt aaaagataaa attccgcata ccttgtttgt tgaagacagt
     2221 gaattttcta atgtaaaagg cttttacaag tttggtttaa ctcaataaaa cagcgaagga
     2281 gatcaacatg aataagggaa aatcagagcg ttatgtagtt ataatcaata gagaaaaggt
     2341 tagcgagtta cctttagcag agtttcttga atccgaatat gaaacactag gcgttaaata
     2401 ctctcagacg atcaaaaaag ctttgaacct atatcggcgt gtaaagaaca atgaagttac
     2461 aattattgaa gcaggcaacg atagaaacga tagcaaagta gcagaagtaa agaataaacc
     2521 aactgatcat aaccctattc aacaagagca tccttcaacg gttacatccg atcattcagc
     2581 aaagaaagaa aagccaatgc tgaaagggtt caatgcacca agtaacaaag acttacttta
     2641 aaaataaaaa ggcgaggtta caatacctag cctttttatt atgtacaaat ataaacataa
     2701 acatatacgt atacatgtat ataaacatgt atacgtatat atccataaac acgtatatta
     2761 aatttagtta agctatacct aaccgcttat tccaataaaa aaagtgatca gctttaaact
     2821 gatcactcac caaaaacttc atcatacaag ttatctatca tttcaccaag taaagctgaa
     2881 tctgatcgaa ttcctaactt ttcgctgatt ttagatagtt tctttctttg cgatggttga
     2941 agcgtgaatt gataattttt cttcttttca gaactatcac tttttagttt agctaccaaa
     3001 gaacttgttg tttctttagg tgtttgttta ggttcttcaa ctgcttcaac cacttcagga
     3061 acttcttcta cttcagcttc agcgaatttt ttaaatctat tttctttcac ttcaatcact
     3121 ccttattctt gtgccgtatc aattattttg ttgtatagcg taaacgtgct ttcaaagaaa
     3181 tccttattct tacgatagat attcttatcc ttagcgaact cagcaatatt cttaccttct
     3241 aagctagttg cattaagcaa ttccttctct tgtacatatc caagataatt agataacgtt
     3301 ggtaccagtt ctaggaactc acgacttgaa ttagtattat gtttgatcct gctaccgatc
     3361 gtagcgtatt tagtttccat cagtgtttca ccagtcttaa tatcaatcaa ctgttttgct
     3421 agtgcatcaa tatctttacc aagcttcagc aaagcttcaa aaccatcttt agatggatca
     3481 gaaatgccta cgacaagatc agatacagcc caagcatttt gagctagtag acctgcatca
     3541 ttatgagtat caatcagaat tagatcatac ttctctttaa gctgttcata gttaacaacc
     3601 atccatctaa acagtagggt tctgttgtta ggcatatcac gcatttgcat ctcaacttgt
     3661 tttaaatctt cacctgctac taaaatatcc atgttctcat ttacagctaa aggttcagct
     3721 gatccatgaa gatataaatg attgattgta ttctctcttt tcgctttact gaaagcatca
     3781 ggaaatcgtt ttgataggtt ttgcgactta tcttcatcaa tatacagcac cttcatacct
     3841 aaattttcga cagcatatcc acctagattg tagattgttg ttgttttacc tgttccacct
     3901 ttttcaatgt ttccagtaat gattgacaac ttcttttcca tgattaaacc tcccttatta
     3961 accttttgta actccattat acactataaa cacgtttatg tatatgttta tatacataaa
     4021 cgtgtttata tttatatttg cttttatatt ctacaacata aacatatata tgtatatgtt
     4081 tatgtttatg tatatattca tatatataac tattgcattt gtcatacaat cgtagtacaa
     4141 tgtaattgaa aaggagttga taaactatgc cagtaataag tattcgtgta tctaaagaag
     4201 aaaaagattt tcttgaaaaa gttgctgaat tcaacggaga taacatttct gaatttatgc
     4261 gtagtaattc cctgcaaaca gcagaaacgt tagtagactt tgccacctac aaggaactaa
     4321 tgaaagagca tgaggaaaac gatcaaagta tttcccacga agatatgcta aaagagttag
     4381 gcttataaga tgacttacca agtaagatat gaacgtgaag ctcaaaaagc gctaaaaaaa
     4441 atggataagt ttcaggcaaa ggttatccta aactggatcg agaaaaatct tgtaggcact
     4501 gatgatccaa gaaaacatgg taaaggtcta acagctaata aatcaggcta ctggcgatat
     4561 agggtaggtg cctaccgtat aatagctgat attagcgagc atgaagtgac aattcttata
     4621 ttgtctattg gtcacagaag tgaagtttat aagtaacaga caagctgata aggcttgtct
     4681 gtttttttgt taacccaaca aaatcactgt ttacgatccc actttaccta aaaaagaaca
     4741 ataccctctt gttattatac acactggtgt gtataatata agtgtaaaca agctaattaa
     4801 ctttcaaaag gagcgatttt ttatgggatg gtatggtgct tattcatcag caaatgaagt
     4861 gatcgaagaa aagaaagggt acgccaaaaa tggtttggaa atcgtagata ccaaagtaac
     4921 gaagacctat ggtattatcc ttttcaaaga tgcagaagga acctacgata ttgacagctt
     4981 catctttcga gatgaaatgt acaaaccaat ctacttctta aatgacagtc ctgcttactt
     5041 taagaaaatt ccgaaaaaat ggttgaaatt ctttgtcggt gatcaagaaa aaatggttaa
     5101 gcaacaacta gatagaatta aagaagaaaa caataaacca aaccttgatg acttattagt
     5161 tgcaggtaaa acttactcaa tctgggatgg atcgtatgtc gctgtttatc agtataaact
     5221 caaacgtagc tttattttta gactacaaga tggatcactc actcggttca ctcgactatc
     5281 agcaggagat gttaaggaag tagcctaaaa cttaaataca taaacataaa cgtgtatacg
     5341 tttatgttta tgtttatgta tatgtatatg aatataaacg tattaggtac gaacgttttt
     5401 aaatgctttt ctgggctttg attttagggt agggctaaaa catccattga tccaaaacag
     5461 ctcagaaacg catttaaacg tatctgatac caatattaca gaaggagtgt atcgtatgat
     5521 taacctattt cttttagtga cagctagtac attattcttt actggaatat cactgataat
     5581 ttcctatttg atctataaga aagccgaaac ttacacaagc aaagcaaccg gactagccgt
     5641 ttcctccttt ttaactttgc tgactttttt tgttactcta tcgttttctt ttgtttagca
     5701 cagctgatcc atcagcaaaa aacctctctt tacattatac acactagtgt gtataatgta
     5761 attgtaaaca agctaattaa cttttaggaa ggagtgacaa tatgctaaca gctacattac
     5821 agcaacctac tcacgttgct attgcagaaa gctatacaat taatgcaggg gtcgttaaac
     5881 agctgatcaa ggatcgagaa ttcaaaaagt ttaacagtcg tcaagcgtat aacagacagt
     5941 taaagaaagc tattctaaag cacaaaaatt ccttcatagg gaaattggaa agtgtggatg
     6001 ttaaaactgt ttcaacggca ttttcagttg ttgaagtgac tattgacggt cgcttgattt
     6061 ctctatttgc ttttggaatt aattgatagg gagtgtggac tttggaaggt aagacttttg
     6121 cagaaatttg gactgaattt attgaggtac caactcgcat tgatccgata acttctgaaa
     6181 aggtattgga tgcagacttc tacaatctca aagcaggtac tagccttgaa tgcgtttaga
     6241 tgtatttaga agagcatttc aaaggcgtaa cgctcggtca cgtcttatac cacaatggtg
     6301 ccgagtggga tgcaattgga aatatccatt tttcttaata caagaaagga gaacacaata
     6361 tgaattatac cgatgaagaa caaatcactt tggaatacgt tttcacaaat gaaaaagggg
     6421 aggaaattga aaaagtcttg atcatttcat caaaagactt ggagaacgct ttgacttatg
     6481 aaccatacga atcaaccgta actgtcaatg aattcttaga tacctatact tctaatgata
     6541 cttgggaaat tatgaatatt tgcaacgcta ataacattca atttgctgaa aaaaccaata
     6601 aatcatttta ttagttttgc aataaaacat cctctttttc tattgattcc atacacaaca
     6661 atgtgtataa tagattttgt aaagggaggg tagctatgcc taagacagca agagaaattg
     6721 taaaaattct caaatctaac ggcttcaaaa agactggaca aactggcagt catgcaaaat
     6781 tttataattc caagactaaa agaacggtcg ttgttccgat ccacaatggt gatgtaccac
     6841 taggaacaga agctaatatc tggaagcaag cagggcttta acagccttgc cttcctattt
     6901 ggtattaggc atactatcct ctcttacact agaaaaggag cgaggaaatg aagacaaaaa
     6961 atatttttta tccggcaatc ttcgagaaag aaggagaagc ttataacatc gttttccctg
     7021 acttaccgga aatatctacc tttggaaata gtcttgaaga agcatattta aacgctaagg
     7081 atgctttagg attagcgcta tatagtgtac cagatgcaga atttcctaaa ccatcagcag
     7141 tggaagaatt aactttgaaa gccaatcaag tagtagtaat catccaacta aacattaaac
     7201 ttttccgaag aagcttaaat acaaaaacaa ttagaaaaaa tgttagtgtt ccggaatggt
     7261 tagttctttt agggaaggag aaaaacataa acttctctca attacttcaa aaagcactag
     7321 aagaagactt gcttgaaaag taaaaaggag accgaaccta tgaaatctac acacttaaac
     7381 tatttctctc gaacgttaat caataatcta ttaaaagata caactggcat tagcgttagt
     7441 accaaacact ttgccaatga tctaattatt tttgaggata ataacttgcg aattgagatg
     7501 tttattgaac aggcaactcc taactcaata cctgaattct gctatacgca cactgaaaaa
     7561 atgaaacatg caaaatcagt taaagatgtt gaagcattaa gtgaatcact aacgaacgct
     7621 ttaaacctcg ttaagaaggc taaattgtta tttgaatttc aaaccgacta ccacaatgag
     7681 ttgcttgctc aatctgaaat tttagattaa ttgaaacagg agaagagaaa gatgaaacaa
     7741 acacaaacag aacccattaa cgatacgctt gctgatcaat tagcaggtta ttataaatta
     7801 tttgagatga gtaaagcaca gcgcttgatc cactatcttt ggaaatacaa aattttgttt
     7861 cttttttggg aagcaacact aacattctca gttctttttt ataagtcaga tttttataat
     7921 caacacttag ttttagggag ttttttgctt atctacacca ttttgatgct taatttatat
     7981 acctacatca cacttgaaga acacttagta attagcgatg cagggatcga gagaaacatc
     8041 aaaagggtat ctttcaagat cacgttaaac aagcctaccg ataaaaagct ctcagaagcg
     8101 ttctgagagc ttttgacatt ttcttgtata atttatccta acacattaca aagcacctaa
     8161 ttcgagctta tatcaagcaa atttgctatt tattcctcaa tacatatcta aaaattactt
     8221 gatggaaaac tagatacatg gtaagcatga aaagaaaatc aatttgagca gatgcagtat
     8281 aatacatagc aatttaaggc tctatacttt ttgatgttgg tgaacttcac caacatcttt
     8341 tttgtat
//
LOCUS       DAFLWQ010000105         8312 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.108, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000105 DAFLWQ010000000
VERSION     DAFLWQ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.108"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(105..629)
                     /locus_tag="L1V16_002585"
     CDS             complement(105..629)
                     /locus_tag="L1V16_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1276869.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="L1V16_002586"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="L1V16_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBN1276870.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="L1V16_002587"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="L1V16_002587"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBN1276871.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="L1V16_002588"
     CDS             complement(2351..3031)
                     /locus_tag="L1V16_002588"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBN1276872.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="L1V16_002589"
     CDS             3157..4026
                     /locus_tag="L1V16_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1276873.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="L1V16_002590"
     CDS             4052..4567
                     /locus_tag="L1V16_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276874.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5207)
                     /locus_tag="L1V16_002591"
     CDS             complement(4614..5207)
                     /locus_tag="L1V16_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1276875.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="L1V16_002592"
     CDS             complement(5232..5411)
                     /locus_tag="L1V16_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276876.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="L1V16_002593"
     CDS             complement(5488..5997)
                     /locus_tag="L1V16_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276877.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="L1V16_002594"
     CDS             complement(6093..6473)
                     /locus_tag="L1V16_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1276878.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /locus_tag="L1V16_002595"
     CDS             6803..7552
                     /locus_tag="L1V16_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HBN1276879.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(7873..>8312)
                     /locus_tag="L1V16_002596"
     CDS             complement(7873..>8312)
                     /locus_tag="L1V16_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBN1276880.1"
                     /translation="KKAEGSPCFLLYQTFPGIGALTAALLLGELGDITRFKTHKQLNA
                     FVGIDIRRYHSGKYTGQDRINKRGNPKARKIIFFTIRNMIRQQRAAPNHIVDYYYKLK
                     KQPIPKKDKVATVACMNKLLKCMHAMVRAHTEYDYAYAVSVDH"
BASE COUNT         2374 a         1714 c         1500 g         2724 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct atttcctacg
     7741 attagtcaag taaaaggtgc aagaaaaata gctcgtaaac gaaagcgaca aaatcaaagc
     7801 acaccaaata aagccccgtt cgtaaaaaat tttcgatctg ggcaaagaag tggtatactg
     7861 taagtggttt agttaatggt ccactgagac cgcgtacgca tagtcgtact ctgtatgtgc
     7921 cctaaccata gcgtgcatac atttcagaag cttgttcata caagcaactg tggcaacctt
     7981 atctttctta gggataggtt gcttttttaa tttgtagtaa taatcgacaa tatgattagg
     8041 agctgcgcgt tgctggcgaa tcatatttcg aatggtgaag aaaataattt tccgtgcttt
     8101 gggattacca cgcttattga tgcggtcttg gccagtatac ttacctgaat gataccgtcg
     8161 gatgtcgatt ccgacaaagg cattcaattg tttatgggtt ttaaatcgtg tgatatctcc
     8221 taattcaccg agcaataaag cggctgtgag tgcgccaatc ccagggaacg tttggtacaa
     8281 caaaaagcaa ggagagcctt cggctttttt ga
//
LOCUS       DAFLWQ010000106         8290 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.109, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000106 DAFLWQ010000000
VERSION     DAFLWQ010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.109"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            476..1339
                     /locus_tag="L1V16_002597"
     CDS             476..1339
                     /locus_tag="L1V16_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBN1276881.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="L1V16_002598"
     CDS             complement(1468..3090)
                     /locus_tag="L1V16_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1276882.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="L1V16_002599"
     CDS             3339..3860
                     /locus_tag="L1V16_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBN1276883.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="L1V16_002600"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="L1V16_002600"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HBN1276884.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="L1V16_002601"
     CDS             5941..6759
                     /locus_tag="L1V16_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBN1276885.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKHHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="L1V16_002602"
     CDS             complement(6862..7059)
                     /locus_tag="L1V16_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276886.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="L1V16_002603"
     CDS             7228..7806
                     /locus_tag="L1V16_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBN1276887.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="L1V16_002604"
     CDS             7901..8038
                     /locus_tag="L1V16_002604"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276888.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
BASE COUNT         2494 a         1487 c         1634 g         2675 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacat cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcagag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc
//
LOCUS       DAFLWQ010000107         7943 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.110, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000107 DAFLWQ010000000
VERSION     DAFLWQ010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.110"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..2009)
                     /locus_tag="L1V16_002605"
     CDS             complement(<1..2009)
                     /locus_tag="L1V16_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBN1276889.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKILTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQK"
     gene            complement(2025..3021)
                     /locus_tag="L1V16_002606"
                     /pseudo
     CDS             complement(2025..3021)
                     /locus_tag="L1V16_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
     gene            3219..4460
                     /gene="sstT"
                     /locus_tag="L1V16_002607"
     CDS             3219..4460
                     /gene="sstT"
                     /locus_tag="L1V16_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HBN1276890.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            4607..5242
                     /locus_tag="L1V16_002608"
     CDS             4607..5242
                     /locus_tag="L1V16_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBN1276891.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            5433..6173
                     /gene="truA"
                     /locus_tag="L1V16_002609"
     CDS             5433..6173
                     /gene="truA"
                     /locus_tag="L1V16_002609"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBN1276892.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(6318..7916)
                     /locus_tag="L1V16_002610"
     CDS             complement(6318..7916)
                     /locus_tag="L1V16_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276893.1"
                     /translation="MLFLSFAYVIPLFMSMGIYHSVNQDTYFHLSRIIGLDNVWSSPV
                     NFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFITFLTMVVSYFSMK
                     QIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLILMGCYEIYIRDYQK
                     WYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLLSLLKATVLTFFLS
                     AGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYTIGLFLFLGLIGAF
                     IFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVWRLNGFSSLFIAYT
                     MSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLTLIAPEDAVAIAEN
                     YNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIELDNSNNKNTVLTTP
                     IYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTKLAIASRYLSIVTL
                     ILFLLYRFTFSKQKQPRREVQHSH"
BASE COUNT         2626 a         1234 c         1491 g         2592 t
ORIGIN      
        1 attttttgtg tcgcccatgt tgcactgtac tggttacctg caacaagatc atattgtatc
       61 agacgataat cttctagaat ttctttttgt ttctcagtta aatttttttc ttggataatt
      121 tgactatcct ctgtaacaaa gacctgtttt ccattaaaac gattagacaa gctttctgta
      181 ggatcaattg ttaatgcagg tagatgatta gatacttctg tcaacaacgc atagtaagga
      241 gttactttga tattcgcatg ctcaagagcc atagcaccaa agttattagg agcaacaact
      301 tctttattta acgtagctgc ttgttcacga ctatacttgt tgttataaat gaaataatct
      361 gtctggtgct gttctaatcc atattttttc gaatcattcc cactatagat tgcgggtaaa
      421 tggtcaccat aaaaaacaaa ggtaatcggt ttatcgattt tgtcgatttc ttggatgaat
      481 ttttttactg ctgtatcggt atagtgaagg ccttgcatat aagtttgtaa ttcttttctt
      541 ctattaggaa tgacagcagt tccttcagca gtgtagttca attcactata gtaatcatca
      601 taaggcatat ggttttgcat agtggataat tggatgaatt gtgacgtttc tgtattgctt
      661 tgtaaagctt tcaaggtttc tttgtatgct gaatcatccg atatgcgtgg gctttgttct
      721 attttatccg tataagttaa tttatccgga ctgtctaaat aatagaacct gtcaaaacca
      781 aatttatcaa acacttgttt tctgcgataa agagcagctg taaaaggatg gatggctatt
      841 ttttcatcga atagatcggt aatatttgga cttattttct gacgctccac tagctgggta
      901 taaggtgtaa ctaacgaagc agacaggtta ctgatactca agcctgtcag tccttcccat
      961 tccatgttag ctgttccgcc accataaccg acggataaca tcaatcctcc tgttccttct
     1021 gttataatgc ttttgatgta aggaataggg tctgtaggta ctgtcagatt agggacacgt
     1081 gcaggatcac tgaagctttc acttaaattg agaacgatcg tctgattgtt taaccagtca
     1141 cttcttgttt ggttgatttc atctgccttt gtgttgtact ttttcattat tccattaatt
     1201 ttttctttcg aatagccagc aggttcttcc atgattttaa tgtcgatatt gtttaggaat
     1261 tgaatgactg gtccgttatc ttttacggcg ccttgctggt taaagaaagt cttgtttact
     1321 ttaaataaat taaacagcaa gaaagaaggc gaatttttgt gattaatgaa aaagacaccc
     1381 gaaaaacatc ctaataatac agcgatactg ataaatcgac gtttccaatg aatcttcaag
     1441 gaatactgtt tttgtagtct acgttgtaca ataatactag taatcaataa taggagaagg
     1501 atcaatccgc ccacgattaa taagactggg ctaaccatcg ataatagttc tgacaatccg
     1561 gtcagtattt ttaaatctga aggaaagaca ggctcttccc gcatttccat tttgattact
     1621 gtcgaaatag tgagcagtaa gttaatgatc aaggtagcag tcaaggcgta ccaaaaacga
     1681 ttggaaatca acaatagtaa gaagaaaaat cccataataa tgatgattgt caggatcatg
     1741 ggtgcttgtc gctgagtaaa tatttttaag gcaacctgga tagtttcttt ccaaccttct
     1801 tttggttcta aaacgaaaat ctgcacgaag gtaaagcagt aaaaaaatgc tgcaactaaa
     1861 aaataacttt tatgaacaaa aagccaatga attctttttt tccaacgctg agttaattgt
     1921 tcaatcgaat caaaagcgaa gtattcgatg aaacgatgaa tgaaacggat tttttgtata
     1981 taaaataaaa agataactag gagggacact gctaataaat agcaaataaa aaactgcccg
     2041 atatttatca gccatgcctt ccctgagttt ggaaattcac gtttcataaa tgtagatacg
     2101 cgataagaaa ctaaagggaa attacatata acttgagtga caatcaaaaa tacagcaaga
     2161 aaatttcctc ttccttttat acctaattta tcagatagca tttctaaaaa taaaaacgaa
     2221 gagaaagtat aatacattgc gaagagagaa tatggtttag aaaacctcag cgctgtatct
     2281 gtatttcctc tgatgatgag tgaaatttgt gtcatcaaaa taatcaaacc gaataaaaca
     2341 atcaagctga taaatacttg aggaagctta tagcggacct tttctttcca gttccattct
     2401 ttcaaaccat aacccattaa aaataaataa aaaatccata aaatactctg tccattctgt
     2461 aatgcaaacg ggtctttatt aaatagagta gagcagccaa ctaatccaat tgttaaaaat
     2521 aatagtagat atttaattgt tgttttcgat aatttattta aaaatccaac tgtataagga
     2581 atactacaaa aaagcaaagt acaagaaaca gcataagtaa agtaattctg actgataggt
     2641 gttaggataa gccaataatc acgaatattc aagctgccag cttgtacgta aaaaaaagat
     2701 attgcaaact agtgtggcta ttaggaatat aaaggcaaaa cgacttaaat aatgtaaaac
     2761 ttttaaacgg gcgatttttt gatattggta acccatgtaa agtgggatca aatttgcacc
     2821 aataacaacg gaagtttgta aaaatgtata gatgtagaat cgaccagggt ttgttgcata
     2881 tgtaggaata gtgactgctg aaatcaatat acgctgtaaa accatcatta tacaagcgac
     2941 aaagattgtc aggaagccat aactctcctt ctttattttt ttcaagaata aacacctcac
     3001 aaaaaaattg gacaaaaaca taagaaaacg tttcctgata agttgcccat taataacatc
     3061 ctaacttaga atatctcaaa aaacaacgtg tagacagaaa aagtacaaaa ttagcaagaa
     3121 atggttgttt gtattgttag aatttttaga aaattatacc tttagtttct ttgcataaaa
     3181 tgatacaatg attgttaaaa ttgtgaaagg gtggtcattt gttagagaag tttttggata
     3241 tgtcgttagt tcaacgtatt gttgttggta ttttagtcgg aatattgttt ggtatctttt
     3301 tccccacatg gacatttatt tcaatattgg gaacgttgtt tgtcagttgc ttgaaggcaa
     3361 tcgcacctat tctggttttt ttcttgacga tggcgtcaat tgccaagcat aaaattggga
     3421 ataagacatt cgtgaagcct attttgatct tatatttagt gggaacattg ctttctgcac
     3481 ttgtagcagt tattgtaagt tcaattttta ctgttcctat tactttacaa gaaacagtat
     3541 ctgaaaaagc accgcaaagt ttggaaagtg ttttatctac tatgttgacg aatgtcacac
     3601 aaaatcctgt tcaatctctt attgatgcga attaccttgg cgtcttattc tgggctgtat
     3661 tgttgggact agcttttcga gcacgttcag aatcgacaaa agagttggtg gatcagatat
     3721 ctatagcgtt gtcacaagtc gtacaagtga ttattgcatt tgctccgata gggattttag
     3781 gattggttta tcaatcaatt gctacgactg gaatagctgg attggcagag tatctgcagc
     3841 ttttacttgt tttgatcggt acgatgctgt ttgtcgcatt agttgtgtac ccattcctca
     3901 cgtttttgtt tattaaagaa aatccctatc cattgatttt cttttgtttg aaagaaagcg
     3961 cacttcccgc tttctttacc cgaagttctg ccgcaaatat cccgataaac atgatgttgg
     4021 ctgaaagatt gaaattgaca aaagagtctt attccatatc gatcccgtta ggtgctacga
     4081 tcaatatggg cggtgccgcg attaccattt ccttgatgac gttgactgct gtacattctt
     4141 tagggattga agcacctttt gttttgaaag tccttttatg tattttgtct gctttagctg
     4201 cttgtggagc ttcaggtgtt gcgggcggtt cactgttatt gattccatta gcatgtagtt
     4261 tgtttggtat ctctaatgat gtcgcgatgc aaatcgtcgg tattggattt attatcggtg
     4321 ttatccagga ttcaatggaa actgccttaa attcgtcaag tgatctgttg tttactgcaa
     4381 taggagagct aggcgcgcgt aaaagaagtg gggaaaaaat caaattgaaa gattgtttag
     4441 atggattaag tgaacgttga acgttagata tttagtattt ttaaaatgat tcgagttttt
     4501 aatgagttat atagatgttc gtgtaaatag aggtttctgt taaatcaaga taaagtcgct
     4561 tataataaca attaaaagca taggtaattg ttattggagg cgtatcatgg attttttacg
     4621 taaatttggt tttttctttt tattattagg cgtgctgagt gattttttga ctccgtacgt
     4681 attaggattg tattatcctg aattagatca aatgaagagc gtgatcagtg tatttggaga
     4741 ggtttccagt cctgtaagaa aagcgtttct tatttggtct gtggtttcag ggatcttttt
     4801 catcctgtca ttgcctgcat tgtatgctgc atttgtaagt acatctcgtg tgttagctac
     4861 cctagttaca gcagccatcg cgttctatgg tataggtgat tgtatcttta caggtttgtt
     4921 cagtatcaat acccatgaat cttcgtggaa tgtctcgaca tgggtccata atatcggatc
     4981 aggtttaggt tacagtggtt ttttattgtt tccagttctt cttttcttga tctatcgaaa
     5041 aaatgggcaa atggacgtaa gccacttata ccttggactg tctgtgatca gtttgctttt
     5101 tgcggcgatt tatggactgg caagaattcc ttctataaat tcttggccat tactgaataa
     5161 aataggtttt tgccaaagaa tcagtttttt ctttaattat gtgcccattg cctggttgag
     5221 tatcttgcat ctcaaacagt aaaacttgag ccgtcaaatt gaacagtcag cggatacttc
     5281 atccggtggc tgttttttgt ttttctgaaa tatatatttc cacagttttc ttgtatagct
     5341 tctgttttag agaagaaagg agctatattt tgtgctacaa tcttaaaaag gtagagagaa
     5401 gaccaaatgg aagacagagg agccactaaa atatgagaaa catcaagttg acaatcgaat
     5461 atgacggaaa aagatattca ggatggcaaa gacttggaga tgacgataaa accattcaag
     5521 gaaaaatcga aaaagtattg catcagatga caaatgaaga gatagaaatt attggatcag
     5581 gaagaacaga tgctggcacc catgcgcgag gacaagtagc aaattttaaa acaaacacag
     5641 aaattggact ggcagaaatg atcgacttta tgaatcgtta ccttccgcgg gatattgtca
     5701 tcaaaagaat cgaagaaatg cctgagcgct tccattcaag atataatgcg gtgggcaaaa
     5761 aatacagcta ttatgtttgg aacaacgtga ttccttcagc atttgagcga aaccacagct
     5821 tttatttccc tcaagagttg gatatggaca agctgaatgc agcttgcgaa aaattagtgg
     5881 gtacacatga tttcattggt ttttctgcat tgaaaaaatc aaaaaaatcc acagtgcgta
     5941 cgattgatga attatctatc gaacgaaagg gagaaatgct tcattttact tttgtcggag
     6001 acggattctt atataaaatg gtgcggatta tcatggggac attactagaa atcggcacag
     6061 gtgccatgcc gatagaaaca atcgatgaaa tatttgaaag caaagtgcgg caacatgcag
     6121 gagaaaccgt ccctgcacaa ggtctgtttt tggatgaagt ttattatcga taaaaatact
     6181 ttgataatgg atgaaacgca tgtttcacag tataaatatc gatgttaaat aatgtatgaa
     6241 gcaaattaaa gaaatataaa aaaagacttt ttagcctgtt tatgtgtaca gctaaaaagt
     6301 ctttcttaaa taaaaatcta gtgagaatgt tgtacttctc ttctcggttg tttttgttta
     6361 gaaaaagtaa atcgataaag taaaaataaa atcaaagtaa cgatagataa atatcttgaa
     6421 gcaattgcta gttttgtgta ctgataagta ataacgactt tatttatacc tggaggaata
     6481 gttaattcag ttgtgccaaa cttagataat tttgtttgta ctagtttgcc attaatagaa
     6541 gccacttgcc ctttataacg ataaataggt gtcgtcaaga cagtattttt attattcgaa
     6601 ttatctaatt caattgtaag tttgttactc ataaaatgag ttgttggatt tatttcctgg
     6661 ttacctagta aatattgatc attattaatc atatcaggat gatagattga ctctttgttt
     6721 gcataatcag tatgattgta attttcagct atagcaacag cgtcttcagg tgctataagt
     6781 gttaatgaat ctttgttagc atggatagaa ttgcttactc ctgagagatg caatattagt
     6841 gcaagaaacg taaagaccat tattttccat gaattatttt tagtagaaaa aatataatag
     6901 atcactatac tcatcgtata ggctataaat aaagaagaaa aaccatttaa ccgccagaca
     6961 aattgtagac tcttaactgg tgtatggtta aaaagttgcc aaggaaataa attggttgaa
     7021 caaaaaagaa caaatacacc aagaaagaaa ataaataaat catcagcagt taattttttt
     7081 ataaaaataa aagcaccaat caatccgaga aataagaata atccaatagt atagttgtta
     7141 tagttattat ttaaaatgtg tgtcagcata tcactaggag ccataccact taattctttt
     7201 cccagtggga ctttcaattc ttgtgctcta gattgttgaa taaaaggaat taagaatccc
     7261 gcacttaaaa aaaaggtgag gacggtagct tttaaaagac ttaagagtct agcgattttt
     7321 tggtcccaaa aataaaaaga aagaaacaac gttcctccaa taaatacaga aaccatagcg
     7381 acagaaagta aatgagtata cactactagc gtcatgccaa tagacaacca gtaccatttt
     7441 tggtaatctc taatataaat ttcgtaacac cccattagta tcaaaggcaa aaatgttaaa
     7501 gcgacagctt ctcccaatga agcacgatgg aatatgtcaa tggcacgata ggcggaaaat
     7561 gtataaataa tcgaaaataa cagcgaaata taacgattgt tttttatttg tttcatagaa
     7621 aaataagaaa cgaccattgt taaaaaagtg ataaaaaaat agtagatatt ataacttaaa
     7681 acaagatttc ccatcatttt ataaaataaa aaagctggat aaagagtaag ccatggataa
     7741 aaaatattca tcattgttcc atgatgatcg aagttattga agtttactgg agaactccat
     7801 acattatcta gtcctatgat tcgagataaa tgaaagtaag tatcctgatt gacactatga
     7861 tagattccca tagacatgaa tagagggatg acgtaagcaa aacttagaaa taacataaaa
     7921 atgatatcta ttatttggtt ttt
//
LOCUS       DAFLWQ010000108         7871 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.111, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000108 DAFLWQ010000000
VERSION     DAFLWQ010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7871
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.111"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(71..1492)
                     /locus_tag="L1V16_002611"
     CDS             complement(71..1492)
                     /locus_tag="L1V16_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1276894.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(1735..3612)
                     /gene="tdc"
                     /locus_tag="L1V16_002612"
     CDS             complement(1735..3612)
                     /gene="tdc"
                     /locus_tag="L1V16_002612"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBN1276895.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(3903..5159)
                     /locus_tag="L1V16_002613"
     CDS             complement(3903..5159)
                     /locus_tag="L1V16_002613"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBN1276896.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(5271..5476)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5739..7040
                     /locus_tag="L1V16_002614"
     CDS             5739..7040
                     /locus_tag="L1V16_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBN1276897.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(7109..7708)
                     /locus_tag="L1V16_002615"
     CDS             complement(7109..7708)
                     /locus_tag="L1V16_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1276898.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
BASE COUNT         2347 a         1600 c         1374 g         2550 t
ORIGIN      
        1 aaaaaactat tcacttggca ggacctccta ctaaatcagc gacaaaacgt cggctgaaag
       61 acttattttt ttatttttct tctaaacttt tttctacctc aatcccccaa gaatctttct
      121 tgaagtgatt gatgatcaat ggaataacga acatgaccac tgtgatagct gctactaata
      181 atgcatcact caatgtcgct gtacctaatg tagcaaatac gacaacgatg atagagaaga
      241 tcagcatgca gctgactacc caagctaatc cgtttccgtt tttaccaatt cggtaaggac
      301 gttcgaattc tggatgtttc ttacgcattt taagcaatga aacagcaatc aaaatgtaca
      361 cgatacaata aataacagtt gtagcatttg taagtgtcaa gaatacagca cttacgtcat
      421 ccattacacc ataaagcaaa gcaaataatg aaataacgat tgattgtgtt agaacgacat
      481 ttctagatac gccgtatttg ttttctttat ggaatccgaa ttttggtgga aggaatcctt
      541 cacgagctac ttggatgatt gtttttgatg gtccagtaac ccaagctgat aattgtaaaa
      601 gcacaccaat aaataccatg aagctgaaga tatttccgat cacttctggt aagcctagga
      661 tttgacagtc aatcaagata ggctgcgtga tatttgctaa ttccattttt ccatctggta
      721 cgacatttgc tacaagcatc gcattgatga cattcaataa aactaatccg atcaaagcga
      781 taaatacgcc ttttgtataa ttttttgttg cgtctttcaa acgaggcatg taaacagaac
      841 tcatttcgat cccaacaaaa ataaatgtga taccagctaa gtatttcaat gaatcaatat
      901 gttccaagtc agggaaagct tttgaccatg aaaagtcacc tagatagccg tttgagacta
      961 gtccgacttt gaaggctgcc aaaacaccta aaacgaacat gatgactact gggatatata
     1021 cccctagcca tacaccgatg ttcccgccga cttttgccat atcgaatttc aagttcaaga
     1081 tcgtgatgat ccagtagata actaaaatac aacctaaaac gaaccagtga ttattgccaa
     1141 gttctacatt accaaatgtg tttcctaaca atggtcctaa agtagaagcg accattacca
     1201 tacctgggaa catttgcacc cataatagcc atgcaacgac aaatccccat ttgctgccca
     1261 gtgctgtttt tacccataac tgaggaccgc cttcttgagg aagcatcgtg gaaagctcac
     1321 cggaaaccat tgatatcgga ccggcaaaaa acaaaactgc aaaaattgaa taaaaaatca
     1381 atgtccaacc gactgcggct aacgtaggaa tactccgaac cgttgcacac agtgccattg
     1441 tcagaccgat aaaggtccca agacccattt tacttacttc agatttactc accgttgaca
     1501 ctctccttga ttttttggat aaaataacgg tgtctttgaa gtagtttcag caataaacga
     1561 aacaattcag cgaatatttg aggggattct ttgagtttat tgcttgaagg gtttcttcaa
     1621 agacaacctc aaaacaaagg gatcgaagag cttaggtctc cccttgctct tcagatccaa
     1681 acatgcgtca gaaacagtta gtattcaagc tgttttctaa catgattacc ttgcttattt
     1741 tgcttcgctt gccaataatt ggtctgcgta gattttttcc aatttttctt gaagagctgc
     1801 tttgattttt tcagcatatt cttcaaagtg ttcttctttg ttcatgtatg gtgtcattac
     1861 gctggcacgc aatacagtta cttttccggc acggttccat tcttcatctg agaatcctag
     1921 ttggttcaca aattgtaatg ggctgttgcc atagtctggg atagcaaagt cagtatgtga
     1981 agttaagaac tcattaccgt aaatgcttcc tttcacgtat gaagaataat catatacgtc
     2041 atggttcaat ttattcattg caactaagtc atcgttgcct ttttctttga atacatagtc
     2101 taccatattg aaatctggat aagttaatgg atgaacttcg atttctttgt ctcctacttt
     2161 aaatgacaag tcattcaaga agttgtagaa acgatgtgca ccttcgattg atgcacccat
     2221 taatttacca tatcctgtga cattcaaagg taagacatgg tgtgctgccc aaacgctggc
     2281 tgctgttgcc cctgcttttg aaccttccaa gatataagcc ccaagtaatg ctgggatatc
     2341 tgcgcctttt tcaaatacat atgtcgcaaa gtaagagata acgtctctca tgcggatatc
     2401 tttgatgacg ataccaccgg cagaatatgg aacatagccc attttatgtg ggtcaatcgt
     2461 tacagattct gcttcttcga ttgctttata tgcactgtgt acttcttcta agatataatc
     2521 tttgttttct gtaaagacat tgtatttgta atgaacatct tttaaatctt caaatggaat
     2581 gaagttgttg tcttcgtcta agaaaatcgc acggccgtat ccgccataag cagcatctac
     2641 gtgtaagtag aagtaaatac cgtctttttc taatacgcga cgcaatgcaa cgattttatc
     2701 gataccgtcg attgctcctt cttctgttga tcctacaaca ccgactacac ctaggattgg
     2761 tgttttttca gctgctagac cacgaacgat tttttcaagt tcgttgatgt ccatgcgata
     2821 gttgtggtca actggcactg gaatcacttg gtctaaaccg ataccgatga tgtcggcagc
     2881 ttttagccat gaatagtgtt tagtttgtgg aaccaaccat tttcctaatt tttctaaatg
     2941 ttttccgcta cgtgctgagt gagctttgat ttcgtcgatt ttttctggga cgctgtctaa
     3001 cagattcatg atttcttctg ttgacaagtt cattaattcc caatcgcttt ttccagcaac
     3061 tagttcaggt gtcacttctt tcattgcaag cggcaatgat ttgatgttgc gggcatacca
     3121 aagtccttct aagtttgcta aagaaccatc agcaacgatg tggccccagc catctttata
     3181 gctcattaat tttgcaaatt ccattcctac ttcttcttcc atttggcttg ttgcaggaga
     3241 agattcatag gcaacgttat taccattcca tagcatagca aaattgtacg ctagtaaaga
     3301 tggcatcaat gtttcagagt tcatatgacc ccagtaacgt ccggcattat gccaaggaac
     3361 ggaatgggta cgcatccgcg ctgaaatttc tgatagaaca tcctttgttt tattcacagt
     3421 gtgttcaaaa ctagcactgc ttttttcttc tggcgtaata ataggcatgt cttgaggcat
     3481 gtagttttga cgccagccta aatgttcatc caccaattca ttcaacaaag ctttatagat
     3541 ttggccgttc tcagctttgt ccccaatgaa tagggcattt aggtttagat ctttcgacaa
     3601 tgattcactc atagtgaaac cctcctaaaa aaatatttaa attttgtcga gccctacatt
     3661 acacctgttc ttctattctg taaactaagt tttggcctga tttttaatca tattttaata
     3721 tgtatcaatt atccgaattg ttcacacttt tgaaataatt aaaaaaaacg agggaattta
     3781 caaatgtaaa ctccctcgca aagattgtat taacgacaac cagcgttcta ttttaggatg
     3841 ggtttcaaaa ttggaatgtt gtaatagtat ttcccttttt caaggtaaaa acttactaaa
     3901 ttctaatcaa ttactttggc caaaaagtaa tttttcttac cttttcgaat aaccacaaac
     3961 ttaccatcga attcatcgga tggatttatg acaaaattta aatcggtaac gcggtcaccg
     4021 ttaatactta tagctccgtt tgaaacatct tcacgtgctt gacgtttaga tggttcaatt
     4081 tttgtggaaa caagcagttc cacgatattt tcaggtgtgc ttgaaatttc aacgttcggc
     4141 attttaccga atccttgcgc gatttcttcc gcatttagtt ctttaatatt tccagagaac
     4201 aatgcttgcg ttattttttg cgcttctttc aagtcttctt cactatgcac aaatcttgta
     4261 acttcttctg ccaaacggcg ttgtgcttca cgtttctcag gttctgtctc tacttttttc
     4321 gctaagtctt cgatttcttc ttgagacaag aaagtaaaga atttcaagta tttcactaca
     4381 tcgcgatcat cttgattcaa ccagaattgg tagaactcaa atggtgaagt tttcttcgga
     4441 tcaagccaaa cggcaccgcc tgcagttttt ccgaatttcg ttccgtcagc cttcagcatc
     4501 aatgggatcg ttaaaccgaa cgcttctgct tctggtcctt ctaattttcg gattaggtct
     4561 aatccagctg tgatatttcc ccattggtct gctccaccga tttgcaattg cacatcgtat
     4621 gttttatgca gatgcaaaaa gtcgatagat tgcaggattt ggtaagtaaa ctctgtaaat
     4681 gagattccta cttccaaacg gctggcaacg atatcttttg ctaacatcgt gttgatgttg
     4741 aagtttttac cgtagtctct caaaaattca agtaaagaga tttttgacaa ccagtcgtag
     4801 ttgttcacaa atgtgatatt tgcatcttta ccaaacaatt ttctcatttg attggaaagt
     4861 gcgtccacgt tatgttgcac ttgttccatc gtttgcaaca cacgttctgt tttgcggccg
     4921 cttgggtcgc cgatcgttcc tgttccgccg ccaatcagaa tatatggatg atggcctgcc
     4981 aattggaatc ttttcatcat cataaatgga atcaaatgtc cgatatgcat cgaatcacca
     5041 gttggatcaa cgccgcaata aagtgaaatg ctcttttctt caacgagctc gcgaagtctt
     5101 tcttcgtttg tttgctgatt aatggcgtcg cgccaagtta attcatcaat aatattcatt
     5161 ttactgacct ccgtgtagtt tttttatgaa agcaggaacc tgctagcatg tgtaattaat
     5221 tatttcttca ggataggata ggaaataaaa aaagtccctt ggcatataag ccaagggacg
     5281 aaatctcgcg gtaccaccca atttgtatgt ctagatatcc aacatacctc tcgaacattt
     5341 aacgctgtcg cgtggcaatc actgccaaag actcctgaaa tgtaattcgc tttaaagcat
     5401 gtactggttt gcagcgacca ccagctttct gaaacattgg ctttaacaac tacttcgttt
     5461 cgatcttcgt cttgttatta ttaatatgtg tctatcatag agcgcaactt tttctttgtc
     5521 aacagaaaaa ggatattttt tttaaattcc tcattttttc ttttttgaat ccgctctaat
     5581 tccgaacatt ttattttcaa ttattgttaa aagaaataac tttttctgta ttttttctgc
     5641 aatttatcga gaagtcactt tactttgcct cttattcttt cttcgttaca ataaggaatg
     5701 ggacaagtaa aaaaatgaaa aagcaaggga cgaggtatat ggaaaaaaag caaaaaatta
     5761 ttttaggagc cacttctgct ttaactatcg ttattttaat tctaagtttg ttttttgtca
     5821 tccgatcatc tacaaaaaaa gaaccaatca ttcctgaaaa aaaaataaca gaaaaagcaa
     5881 aagaaccgac agatgataag caacaactag ttactcaagc aaaaaatctg gctcaaagct
     5941 acgattatga ccaagcgatt gcgttattgg aaaaagatag taagaacgga tctactgaaa
     6001 cacaacagct tcttcaaaca ctaaaaaagg agaaagaaca actgatcgac tggtctgatc
     6061 ctactcagat ctctcatgtc tttttccaca gcttgatcgt ggacccgcaa aaagccttcc
     6121 actctcaaca ggcacaagga tacaaagatt atatggtgac tgttgaagaa ttcaaccgtt
     6181 cgatcgaaca actttatcaa aatgattttg ttttagttaa tttgaatgat ttgatccaaa
     6241 aagacgaaca aggaaatctt tcctttaacg ggcttgcgct acctgaagga aaaaaaccat
     6301 tggttctttc acaagatgat gtcagctatt atgaatatat ggataattcc ggttttccta
     6361 gccgattggt cgtatcaaat aacaatgaaa tcaaaaatgt ctataaagag aaagataaag
     6421 aagaaatcgg tgactttgac atggttcctc tgatcgatgc ctttgtcaag aaacatcctg
     6481 atttttctta tcgaggcgca aaaggtacct tggccctgac aggttacaac ggagttttag
     6541 gttatcgaac atcaaaatct caatatggag acaatgaaaa aacaaaaaaa gagattaaag
     6601 aagctaaaaa agtggcggaa cagttgaaga aagacggctg gagctttgct tcccatacat
     6661 ggggtcactt gaatatgact caagcttcac tagaagatgt aaaaaaagac aatgaattgt
     6721 ggcagcaaga agttgcacct atcctaggaa aaacaaatat tctgatttat ccatttggtg
     6781 cagacatcag cgactggcag ccttattcag cagaaaatca aaaatttgct tacttgaaga
     6841 gtcaaggttt cgatattttc tgtaatgtcg atgcttctac accagcttgg ggacaattag
     6901 gtacggattt ctatcgaaat gctcggatca atatcgatgg cattcgtttt caatctgatt
     6961 tagacggaaa aaatcctatt cttgatccat tcatcaatgt ccatgatgtc tatgacaaag
     7021 aagcacgcga atctgcttga ttttacgtca tttatgaacc aaaaaagccg aactgacatt
     7081 ttatcgtcag tttcggcttt tttatgcttt atttcttctt cggtgcgatt cccttgatca
     7141 ggacttctgt ccattctgct gtatatggaa gcagttttgc gtatatctcc ggcttagaaa
     7201 ttccttctac cattgcttga aaatagagga tcaagaactc atccgaatat ttcaaatcca
     7261 cttttccttc tttccgccct cgatggaaaa gatcaagcat gatactgaaa ctttcttgcg
     7321 tatacgcatc catcgcgtca gaaaattctt ttttttcttt ttttgtatag tatgtcatca
     7381 aatcgatata aaattgtttg ttcactcgat tgagataacg gattttgttt tcactcatgg
     7441 caatcagtgt ttcttcaaat ggaagatttt ccgcaatcaa cgctttcgct tcttgcccta
     7501 aatcattcat aaatgcaaaa aatacttcat aaatcagccc ttccttgctg ccaaaatatt
     7561 taaaaatcgt cgctttactt acctgagcgt tctcagctac cttatccatt gtcactccag
     7621 cggttcctat gtctgtgttc atcaagtcaa aagctgcttg taaaatctct ttctttttct
     7681 cttgtgctct cttttcaaaa ccgttcattt gtagagcctc ccgtaatttt aaacttttat
     7741 aatatatata gttcaaattt attctgaggt ttattataac tatctattga gaaagtatca
     7801 agctagcaat tccttgttta tgaattcatt gacagaaatt tataaaaaga atattatgta
     7861 ctaaaataat a
//
LOCUS       DAFLWQ010000109         7741 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.112, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000109 DAFLWQ010000000
VERSION     DAFLWQ010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7741
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.112"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            204..545
                     /locus_tag="L1V16_002616"
     CDS             204..545
                     /locus_tag="L1V16_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276899.1"
                     /translation="MEKELSTLDQYLTDPSWGKSNIKETSNRKIRRNLLTDEQLACDQ
                     DDLGNFVSIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYERDNLIDISYYGQGKK
                     YIAEMEAELDE"
     gene            538..1284
                     /locus_tag="L1V16_002617"
     CDS             538..1284
                     /locus_tag="L1V16_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBN1276900.1"
                     /translation="MSEKEQPLKNRSDNTLFNSLYKINVKGVTEKRNDLTYLSWAWAW
                     AEVSKVCEAVDYEIYRDPETHRPYLFDEKTGYMVFTSITVNGVKRDMWLPVMDGANKA
                     MKDEPYTYEVNDYQWNNETKKKKIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLG
                     LYIFAGEDMPEDVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASITAD
                     DSKWTKRDLGILKRGVNWLEDQYREETKEK"
     gene            1290..1976
                     /locus_tag="L1V16_002618"
     CDS             1290..1976
                     /locus_tag="L1V16_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276901.1"
                     /translation="MFKPLIDSYSAVLRRFKGNQIVARINEEVNIERLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            1979..2809
                     /locus_tag="L1V16_002619"
     CDS             1979..2809
                     /locus_tag="L1V16_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HBN1276902.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLGSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDIDIDKE
                     EKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKNNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            2826..3677
                     /locus_tag="L1V16_002620"
     CDS             2826..3677
                     /locus_tag="L1V16_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1276903.1"
                     /translation="MESLASTMEKLIRRVLVQSGRCPECSEPLYSWRGKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALEKAKSYTNEVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            3674..4033
                     /locus_tag="L1V16_002621"
     CDS             3674..4033
                     /locus_tag="L1V16_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBN1276904.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            4048..4209
                     /locus_tag="L1V16_002622"
     CDS             4048..4209
                     /locus_tag="L1V16_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBN1276905.1"
                     /translation="MTTEEVIQMRIRSIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            4206..4511
                     /locus_tag="L1V16_002623"
     CDS             4206..4511
                     /locus_tag="L1V16_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276906.1"
                     /translation="MSVDKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKTR
                     RRMPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRAKNMDIDSKGRQFRYVEEK"
     gene            4511..4828
                     /locus_tag="L1V16_002624"
     CDS             4511..4828
                     /locus_tag="L1V16_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HBN1276907.1"
                     /translation="MNLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILDEYME
                     GSK"
     gene            4825..5211
                     /locus_tag="L1V16_002625"
     CDS             4825..5211
                     /locus_tag="L1V16_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276908.1"
                     /translation="MIPRFRSWYTPFKGKTIGQEMKYGQAGRLITHAEMAPDKYVLMQ
                     STGLKDKNGVEIFEGDVVLVNVSNGFDHLVNEKTVVQESEFHSGLVCKSLISGMEYRI
                     FSHQKMGYEYEVTGNIHENSELLEVE"
     gene            5208..5543
                     /locus_tag="L1V16_002626"
     CDS             5208..5543
                     /locus_tag="L1V16_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276909.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDIHGKSKSAIKLFGAIEIYADDF
                     PNLWLKEEQ"
     gene            5689..6258
                     /locus_tag="L1V16_002627"
     CDS             5689..6258
                     /locus_tag="L1V16_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HBN1276910.1"
                     /translation="MNKQEAIKKLESIKVIGNDALAACYNESINAGITLMKKIDEPKK
                     LVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLYSVIIAGEYLVKEISCSNEVKLVSTAYLPQYLAH
                     HYQLTEKQIKAIDERYWPFAVPVEEVAEG"
     gene            6255..6428
                     /locus_tag="L1V16_002628"
     CDS             6255..6428
                     /locus_tag="L1V16_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276911.1"
                     /translation="MSRQIMLHIPDGTKAMTITIVAAQKDGGLALKTKSIDTKQILEG
                     RDVEIEIDEEEAE"
     gene            6425..6730
                     /locus_tag="L1V16_002629"
     CDS             6425..6730
                     /locus_tag="L1V16_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276912.1"
                     /translation="MNVQVYLKRDLARFPRSWDTNSHPSEAEEEGYLMSANMIEITRD
                     DADEFDKKRSWYSVPNPMYTAVIEDYHISDRFILIDLERPKKRIKQYRRCGFSTKKW"
     gene            6754..6951
                     /locus_tag="L1V16_002630"
     CDS             6754..6951
                     /locus_tag="L1V16_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBN1276913.1"
                     /translation="MNNRHRRVAKLRNQELNVAKVKFEREYGVSAEETYKVASQCVAD
                     ASDAIRKFGISILDIKWEDTE"
     gene            6948..7154
                     /locus_tag="L1V16_002631"
     CDS             6948..7154
                     /locus_tag="L1V16_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276914.1"
                     /translation="MKIYVVKFGNQFYRSDERSIGANTLSIVDILQSARWFDNLEEAN
                     QVSRRLGGLTQVYELVTVDHEGVE"
     gene            7154..7450
                     /locus_tag="L1V16_002632"
     CDS             7154..7450
                     /locus_tag="L1V16_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276915.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTREKPKFKVGDMVRCEA
                     EGFIYPFRGYVEKVLSNSAIIRIENTMECDKWLAKSKENLAVARLVDMEVIESK"
     gene            7526..>7741
                     /locus_tag="L1V16_002633"
     CDS             7526..>7741
                     /locus_tag="L1V16_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBN1276916.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAI"
BASE COUNT         2879 a         1191 c         1766 g         1905 t
ORIGIN      
        1 agacttttcg gtgatgaaaa tgaatagagc tgaagcgcta agaataggga cggtaattgc
       61 taatcgctgg tggagacaca ataaaccaag catcctaagc caacaacata ttgataagca
      121 aaaagcttgg caacaaataa aaaagtgact ccgccggcaa gcatagagtc acaaagaaaa
      181 tacatctaag gagatgttac cacatggaaa aagaactttc cactctagat caatatttga
      241 ctgatcctag ttggggcaaa tcgaatatca aggaaacaag caatcgaaaa atcagacgta
      301 atcttttgac ggatgaacaa ctagcatgtg atcaagacga tttgggcaat tttgtgagta
      361 tttgggatca tgtctatctt atccatctat caaaacattc aaacaaacct gaatacatct
      421 atgtcatcga agatggcttg attgatgcgc tcgaagagta cgaaagggat aacttgattg
      481 atatctctta ttacggacaa ggcaaaaaat acattgctga aatggaggca gaacttgatg
      541 agtgaaaagg aacaaccttt gaaaaataga agtgataata cgctttttaa tagcttatac
      601 aaaataaatg tgaaaggtgt tactgaaaaa cgaaatgacc tcacttatct ttcgtgggca
      661 tgggcttggg cagaagttag caaagtgtgt gaggcagtag attatgaaat ctatcgtgat
      721 ccagaaacgc atcgtccata cctctttgat gaaaaaacag gctatatggt ttttaccagt
      781 atcacagtca acggagtaaa gcgtgacatg tggttaccag tcatggatgg tgcaaacaag
      841 gcaatgaaag atgagccata tacctacgaa gtcaatgatt atcagtggaa taacgaaacg
      901 aagaaaaaaa agattgttgg aaaaatcgaa aagcgagttg aagcagcaac tatgtttgat
      961 atcaacaaaa cgatcatgcg ctgtcttgta aaaaatctag caatgtttgg gctagggcta
     1021 tatatatttg ctggcgaaga tatgccagaa gatgtctcga tgcttgaacc agctactcaa
     1081 agaagcaaaa agctattctt ggatgcttta caactggttg ctaacaagta cgaaaaatca
     1141 attgatgaag caattgttgc attgactgat gcagcttcca taaccgctga tgacagtaaa
     1201 tggaccaaga gagacttggg cattctaaaa cgaggcgtta attggcttga agatcagtac
     1261 agagaagaaa caaaagagaa gtgatatgaa tgtttaaacc gttaatagac tcatactcgg
     1321 cggtactaag aagattcaaa ggcaaccaga tagtggcaag aatcaatgaa gaagtgaata
     1381 tcgagcgatt gaagacgatg tatgacggct acgatggcga tcgagtcatt gaaattcgct
     1441 ttattgatcc acgtcggttc acagtacagc aaagaaactt catctatgcg ctcataggcg
     1501 atattttcat cgatacaggc atgccaacgg acttctggaa ggaattcttc tacttccgtt
     1561 ttgaaggtgt cacagggcgc aaaataagcc tcaaagatga atcgaataca actgtgagtg
     1621 atgctaatgt cttagcaaat atcattttag atttcatctt tgaacatcat attcctttca
     1681 aagaaggata tgagatttta ccagcgaatc aagagtatta cttctacaaa tgcattacaa
     1741 aaagagtctg ctgcatctgt ggcaaaacag gagctgatat cgatcacttt gacaaagcgc
     1801 tgggaagacg aaagcgcaag gaagttgatc attcagagta cacatttgca gcactctgca
     1861 gaatccatca cacagagaaa cacaaaatag gtgtgatcaa tttcaaaaat aaatatcaaa
     1921 tcaaaggaat caagttaaac caggaaacaa ttaaaaagtt aaggatagga ggataaattt
     1981 ggctgagata agttggatca aacttaaaac tactatgttt gacgatgaaa aaatacgatt
     2041 aatccaagct gttcctgagt cggatgccat catcgttata tggattcgat tactagtttt
     2101 agcaggaaag actaacgacg atggtctgat atatatccag aggaacatgc cttataccga
     2161 agaaatgctt gctacattgt tcggcaaaaa cgtaaatacg gttcgcctag cgctaactac
     2221 attggcaaat ttcaacatga ttgatctagg cagtgatgga ctgattgcca tcagtaattg
     2281 ggaaaaacat caaaatatcg aagggatgga taaagtaagg ctaaaaaacg ctgaaagaaa
     2341 ccgtaaatac agagaaagaa agagacagga acgtctcaaa ttggaaaatg acgttagcgt
     2401 gacgtcacgt gacggtacag ataaagatat agaagaagat atagatatag ataaagaaga
     2461 aaagaaaggt aagtattctg acgaacactt acgccttgct aaaaagttgc aaagtaattt
     2521 aactgaagat tttccaaaag aaatgaataa agtagatatc gaaaaatggg cagacacaat
     2581 caggttgatg gaagaaagag ataaagcatc tatagaagcg attgagtatg tgatcaattg
     2641 gctacctaca aatgaatttt ggtttggaaa tattagaagt gctaagaaac tgcgagaaaa
     2701 atttgagaag cttaaattcg aaatcaaggc agataaaaat aatcataaaa agcaaagtca
     2761 aaaattacag tacagcaatc ctagtgaata tgacgacttg ccaatttaaa aaggagatgc
     2821 atcacatgga aagcctagca agtactatgg aaaagctaat aagaagagtt ttagtacaaa
     2881 gtggaagatg cccagagtgc agcgaacctt tgtatagttg gcgagggaaa aataaggacg
     2941 ggtcagaacg ttgtaaacca acatgcatga gttgtggtta taaagcgtta cgtgtgaaag
     3001 aggatataca gaccgaacgg atatataacg acagcttaaa agcacgagcg ttgagttttt
     3061 ttcaaaatgg ttcggtatta acagataaaa ctttgtttaa atgcaaaatg gaaaattatc
     3121 acgtagtgga tcaagaaaca aaaatcgctt tagaaaaagc aaaaagctat acgaatgagg
     3181 ttctgctgaa ccatcctgca catttcattc tatcagggaa atcaggaagc gggaaaagcc
     3241 acttatcaat ggctacagct tgggaaatac ttgagcgctc aaattatgac aagaaaatac
     3301 tttttataag ctatcaagaa ttattagagc aaataaagtt ttcttataac aatgctgaac
     3361 tgagaaaaga aattgaagga tcgcttatag ccgatattaa aacaactgat ttggtggttt
     3421 ttgacgatat tggagctgaa ttaggtagtg gggtatcaaa tagtaggcag tttacaaaca
     3481 acacgttaaa cacgctctta gaagcaagac agaacaaggc aacgatcatc acaacaaact
     3541 tatctggtcc tgaactaaga gaagcctacg gtgaaagaat tgtttctagg atatttaaga
     3601 attcagaagg ttatgcgctg aaattccagc aaacagcaga caagcgcata aaaccagtga
     3661 aaggtagtat cgcatgaata aataccgtaa taaaaaaact gttcatcgag gtatcaagtt
     3721 tgattctatc gcagaagcag agtattacga tctagccttg tggcaagctg aagcgaatgg
     3781 ctggaaagta aaacttcagg aaagatttga gctgatgccg aaatttgaac tagacggaaa
     3841 gaagtatcgc aagatcgagt atattcccga cttcacattt tataaaaacg gcaaacttgt
     3901 caaagtcgta gatgttaaag gaatgcagac aaaagacttt aagatcaagg caaagctgtt
     3961 ttgtcatcaa tatcaagtgc cgttgatatt agctaaaaaa tatcggaata cgttcaagga
     4021 agagcgtttt taaagaggtg gtctatcatg acaacagaag aagtgattca aatgcgaatt
     4081 cgaagcattc aacgtgagat tgacgatctg gaacgaacaa aggcagtgat ggtcaatgaa
     4141 acggcgagaa aggcaatcga tttgcacata gagaacttaa gaagggaaat tcgtagattg
     4201 gaggaatgag cgtggataag aaagcagcaa tgaaacgaat catcgaactg acacattctg
     4261 agaattggca agaagacaaa gaaatagttg cagaagtcca aaagctcggt aaatcaatgt
     4321 ggactgaaaa aaccagacgg agaatgccga gaaaaattgc aatctggcac ggtgaccgaa
     4381 ttctagtaac aggtaccgct gaacagttat ctgaaattac tggtctgagc aaaaacatca
     4441 tctgggatag agcgaagaat atggatattg attctaaagg aagacagttt aggtatgtgg
     4501 aggagaaata atgaatctca ttacacaata cagtgatatc atcctcaaga aaatcatgat
     4561 gaagattcag aaagacaaaa aatcaaaaga acgagcggaa ttagttaagt tggaaatggc
     4621 tgaaacaggg gcaggagtgc gaagtagcag gcattggaag gcagcagcaa acattgaatt
     4681 ttattacaac gaaattcaaa aagggttcga tcaaatgcgt gagctggatc ggcaaacaaa
     4741 ttggagcaag aaacttcatc aagatcgttt caaatttgta gagaaatata aagagatatt
     4801 agacgaatac atggagggca gcaaatgata ccgagatttc gatcgtggta cacaccattt
     4861 aaaggtaaaa caattggaca agaaatgaaa tatgggcaag caggaaggtt gatcactcat
     4921 gctgaaatgg ctccagataa atatgtgctt atgcaatcca caggactgaa agataagaat
     4981 ggcgtagaaa tatttgaagg ggatgtagtt ctggttaatg taagtaatgg ttttgatcat
     5041 ttagttaatg aaaaaacggt tgtacaagaa tccgagtttc attccggatt agtttgtaaa
     5101 tcattaatta gtggaatgga atatagaata ttcagccacc aaaagatggg atacgaatat
     5161 gaagtcaccg gaaatataca cgagaatagc gagttattgg aggtagagtg attatcttag
     5221 ctactgacta catcgattct ttaaaagatg aaaatgggaa tgtcccagca ttgctaaatt
     5281 gtggaattaa aagtaagaat agaatcattt tgttacggat atcggctgat ttagcaaaat
     5341 atctttatct gagcaagaca gcagtatatt acactgcggc tacacgttat cagtacaagg
     5401 gaaaaacaat cagtcaggat tattatgatc gtttaatcag tcctgacata catggaaaat
     5461 caaaatcagc gatcaagtta tttggcgcaa tagagatata tgccgatgat tttccaaatt
     5521 tatggttgaa ggaggaacag taatgaaaga ctggttagaa gaagcaagcg ccttagttgg
     5581 ctgtttcata aactgtgcgt ttatatctgt aattattgca ctggtgggat ttgtatcatt
     5641 gaaagtgatt atattgcttt ggcagttaat tttttaggag gaacagcgat gaataaacag
     5701 gaagcaatca aaaagttaga aagtattaaa gtgataggaa atgatgcact agctgcttgc
     5761 tataacgaga gtataaatgc aggtattacg ttaatgaaaa aaatagacga accgaagaag
     5821 ctagttattc cacaactcgt ggccggttgg cttgagaaat ctacggaccc ttttacgaaa
     5881 gctgaaaaaa tagcgtattt aatcaaatct aaagatggtg attcatatta tttctgtgat
     5941 tggtttgtac gagatggcat agtgacgcaa gaacaaggag aagaattact cgcttgggca
     6001 acgagacaat catatgaaac actattgagc ttgtacaacg gctacgaggt cgagaaagag
     6061 ccgttgtaca gtgtaataat tgctggcgag taccttgtca aggagatcag ttgcagtaat
     6121 gaagttaaac tagtatcaac agcttacctg ccacaatacc ttgcacacca ctaccaactg
     6181 accgaaaaac agatcaaagc aattgatgaa agatactggc catttgctgt gccagtggaa
     6241 gaggtggcgg aaggatgagt agacagataa tgctccatat accagacgga acaaaggcaa
     6301 tgacgattac cattgttgct gcacaaaaag acggtgggtt ggcgttgaaa acaaaaagca
     6361 ttgataccaa acagatttta gaaggcagag atgtcgagat agagatcgat gaggaggaag
     6421 cggaatgaat gttcaagttt atttaaaaag agatttggcc aggtttcctc gaagctggga
     6481 tacaaattcc cacccatccg aggcagaaga agagggctat ctaatgtctg ctaacatgat
     6541 agaaattaca agagatgatg cggatgagtt tgataaaaaa agatcatggt actcggttcc
     6601 gaatccaatg tatacggctg taatagaaga ttatcatata tccgacagat ttattctgat
     6661 tgatctagaa aggcctaaga aacgaattaa acagtataga cgttgtggat tttcaacaaa
     6721 gaaatggtga taacaaaaca gaggtgaaga aaaatgaaca acagacaccg cagagtagca
     6781 aaactaagaa atcaagaact gaatgtagcg aaagtaaagt tcgaacggga gtatggtgtt
     6841 tctgcagaag aaacatataa agtggcaagt cagtgtgttg ctgatgcaag tgatgctatt
     6901 cgtaagtttg gaatttcgat actagatatt aaatgggagg atacagaatg aagatttatg
     6961 tagtaaagtt tggaaatcaa ttttacagaa gcgatgaacg ttctataggg gctaacacat
     7021 tatccattgt agacatactc caaagcgcaa gatggtttga taatctcgaa gaagctaacc
     7081 aagtttcacg acgacttggt ggattaacgc aagtatatga actggtcact gtcgatcatg
     7141 agggggtaga gtaatgaaac taaaagacgg attttacgct agtagtcatg gtatcggcgg
     7201 tttgatgcta gatatgccga caaagaaccc taaaacacgt gagaaaccaa aattcaaagt
     7261 cggtgacatg gttcgctgtg aagcagaagg atttatctat ccatttcgtg gatatgtaga
     7321 aaaggtattg tcgaactcag caatcattcg tattgaaaac acgatggaat gtgacaagtg
     7381 gttagcgaaa agcaaagaga atttagctgt agcgagatta gttgacatgg aagtaatcga
     7441 gagcaaataa aaaagccgga tcgctccgac taacataata aaacagacaa gtttattata
     7501 tcacataaag gagcggtttg acttgatgca attgttacga gaggtagatt tcaaacagac
     7561 aagatgtaat gcgagagatg tgctgaagaa ctttcggcgt ttggagcgga tggcaggtcg
     7621 ctctttgata gatattaagt ctccaattat tacggatatg ccgaaggcgc cgaagcacgg
     7681 caataaggca gaggacgcga tcattcagat gatggatata gaagcagaga gagatgcgat
     7741 t
//
LOCUS       DAFLWQ010000110         7670 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.113, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000110 DAFLWQ010000000
VERSION     DAFLWQ010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.113"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..813
                     /locus_tag="L1V16_002634"
     CDS             <1..813
                     /locus_tag="L1V16_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HBN1276917.1"
                     /translation="KKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSD
                     NGQIKLLWKSPLSTEKNGVSSLTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSG
                     DNFIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIES
                     KSLNQDQIIKYANYCGVYPKKIARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHAL
                     ALFGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            807..1229
                     /locus_tag="L1V16_002635"
     CDS             807..1229
                     /locus_tag="L1V16_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276918.1"
                     /translation="MVNKLIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2363..3331
                     /locus_tag="L1V16_002636"
     CDS             2363..3331
                     /locus_tag="L1V16_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBN1276919.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSIISRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGIA
                     NFSKEDFHELLDIPKSYRESDINKKIIKPIRQELTAIFKGLTIQKRYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKEPTSLQEKIKEQKRKLELL
                     QQLAELERKQNTPSKKINKQIADNNSDITPEFKENLLDNLQNLFKE"
     gene            3341..3829
                     /locus_tag="L1V16_002637"
     CDS             3341..3829
                     /locus_tag="L1V16_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBN1276920.1"
                     /translation="MTDKTIKELADILGVSKDKVKYQLRKLPSNFTYKKGNITYLKKE
                     AVTTITKVLSGNESGNLPSELPDSLPTDYLLKEIETKNNHIEEKDRQIEKLQIALETQ
                     QKLLDQQQQLTLQANQQIKKLHEQLQLTYAEESSEKEPLSVTEETQKGQNKEKKWWQF
                     WQ"
     gene            4125..4406
                     /locus_tag="L1V16_002638"
     CDS             4125..4406
                     /locus_tag="L1V16_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276921.1"
                     /translation="MDILVRNIDPKVISEIDRRCQELTTKTGKKWSRNAYLKVLIEND
                     FDQALRHYKKDQFDLLLEKFIDIQAKNTETLNDYVHTNNQLIETLIGGI"
     gene            4408..4824
                     /locus_tag="L1V16_002639"
     CDS             4408..4824
                     /locus_tag="L1V16_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276922.1"
                     /translation="MRKTSVQKHVTLYPSHIDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPNTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSRNFDPTNFLKR"
     gene            complement(5579..6727)
                     /locus_tag="L1V16_002640"
     CDS             complement(5579..6727)
                     /locus_tag="L1V16_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1276923.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     gene            complement(6744..7148)
                     /gene="tnpA"
                     /locus_tag="L1V16_002641"
     CDS             complement(6744..7148)
                     /gene="tnpA"
                     /locus_tag="L1V16_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HBN1276924.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
     gene            7329..>7670
                     /locus_tag="L1V16_002642"
     CDS             7329..>7670
                     /locus_tag="L1V16_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HBN1276925.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYVYTV"
BASE COUNT         2710 a         1327 c         1246 g         2387 t
ORIGIN      
        1 aaaaaaaata caaatggaga atattcagga agtatttcac aatttttagc aaaagaactt
       61 caaaatctag tagatagtaa tataacagat acaaccttat tttttcaaga taatagcatt
      121 tattattccg ataatggaca aattaaacta ctttggaaat cacctttaag tacagaaaaa
      181 aatggtgttt cttcccttac agaaaaaaat gatcttatat ccgtaaatat aaaaaataaa
      241 attaaaaatt tttctaaaaa acaaaatttt cctgcggtta aacgtgtaaa aagtgtctcc
      301 tccggagata actttattat gattaattgg cgtatagcag aaacccaaac aagttttccg
      361 tggtgcgctg cttacgtaga agctgctatc ttatgtaaca aaacagatgt acgtgctact
      421 tcagctagag ccattatgca ttatacctat cctaatttaa acaacagtca aattgaatca
      481 aaaagtctta atcaagatca aataataaaa tatgcaaatt actgtggtgt ttatcctaaa
      541 aaaatagcac gaatactaaa cctttcagag gtccaaacac aactaagaaa aggaaatgcc
      601 atttatatgg gaactgctgg ttatggaaat tatagtaaca gccgtcatgc acttgcatta
      661 tttgggtggg tcaatcaagg tggttatcaa acttactatg tgtggaatcc ttggtataac
      721 tacccaactg taataagtgc aaatgcagga ccagttacaa ttcctgtacc tggaggtggt
      781 tttacttggg acaataccat tacaaattgg taaataaact cattgcttta gttatgggtc
      841 tagtgttagt tcttttctta actagttgtt caaaaaaaca agaaatacaa aagactgatc
      901 tgattccttt tctaggaact tggcaaacta aagatcattc agaacgtcta gtaatcacta
      961 atttaaatac ttcaaaaaat atagaacaat ataccatctt agtaaaagag aacaatcata
     1021 aaattcaaat cattgataaa aatttaaata taaatgaaca agttttcatt tacaaagcaa
     1081 caaataattt actaacactg cgctcgaata aaaaacaatt agattacact tttagtttgg
     1141 attctccaaa aaagctcgta tttattttga caacgaatga tgggacagaa gggacagcta
     1201 aaccaattga attttttaaa gctgattgat gaatagttgt ttgatattac aaaacaataa
     1261 tttcaccgaa ggtgaaacaa gcgaaacttt acaaaaagtg gctagcattt gctagccttt
     1321 tttgtattgt ggagcgtggg ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1381 aagcggttat ttgcaccaaa tacgtaggta tttggctagc aaatatagag cttgccaagc
     1441 cctttagtgt gttttgtaga aagggacctt atagtcactt tcacattaca aacgatacgt
     1501 cctatggacg tatcaaaagg gtgggactta tgagcaaatt aaagcaaaat ttggctagca
     1561 atccttctaa aaaatacacc tattgatcag agtcaaaata aatcagtttt cgagtgagcg
     1621 aatccaaatt tgcaactctg aagctttgca aatgagtgtg ccggcttccg taaaagtcta
     1681 ggtaacatta gtcgatatat acatagggct ctaatttgcg ttttaaggcg ttttaaacgt
     1741 tctggtatgt aattatacca aagcgacttt aaaacgcctt aaaacgaatt ttagaggttc
     1801 tgtagaacgt tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg ctttaaaaac
     1861 aagataaggg attttatcta gacttgtctt aaaacgccgt agatgagcgc tcagagcttc
     1921 taaaaggact ccttacgaac tgtttttaag caaaggagcc tttaggcgac tgcgcagttt
     1981 aatgtgagag cgtagcgatc acacctttaa agcgaccgta gggagcagat tcccagttta
     2041 ggaaatttcg cgaacctgtt tggagaaaaa aagtaggaaa attttaggcg ggaaattttg
     2101 cccccctctt ttataatctc ttttataacc tctttttaaa cctctttacc gtcggctgta
     2161 tccttactct cccaaggtgt gcagaatctt ttaggggtct ttttgtctgt ttttaggggt
     2221 ctttttgtct gtttttaggg gtctttttgt ctgtttttag gggtcttttt gtctgttttt
     2281 aggggtcttt aattaggggg ttgaccccca ttagaaagct ctttataatt ttgttaagta
     2341 gttaatcttg aaggaggatt ttatggcaaa tgaaattgtg aaataccacc atgaattaaa
     2401 tacgattcct ttacgcaaat ttacgtcagt agaaatgaat ttattcttct ctataatatc
     2461 tagaatgcgt gatgtaggcg ataaaaaagt acaatttaca ttcgaacaat taaaagattt
     2521 aagcaattat aaagcaactg caaatgttcg attcatagat gatttagaaa caacgtatga
     2581 caaattaatg gatttacgtt ttggtagaag aagtgctgac ggtttgcaac gtgaacgatt
     2641 tgttttattt aatcaattta aaatcgatgg aaaagctgat attccttttg ctgaaataca
     2701 agtccatgag aaagccttac ccttacttaa taatcttgaa gaatgggttc gatattctct
     2761 ccaacaattc aatgaattag aaagcagtta ttccaaaacc atgtttagat tattaaaaca
     2821 atacagaacc aaaggaattg ccaatttttc aaaagaagac tttcatgaat tacttgatat
     2881 ccctaaaagt tatagagaaa gtgatataaa taaaaaaatt ataaagccta ttcgccaaga
     2941 actaaccgca atcttcaaag gtttgacaat ccaaaagaga tacggaaaag gacggggaaa
     3001 gcctgtcatt ggctatcaat ttacatttaa acctgagata aaaaaatcag acgactttaa
     3061 caaacatgct ccaaccaaag aagaacaaaa taaagctttg gaactagcta atcaacaggt
     3121 tcaatctgaa aaagaaccta cttcattaca agaaaaaatc aaagaacaaa aacgaaaatt
     3181 agaactttta caacagttag cagaattaga aagaaaacaa aataccccaa gtaagaaaat
     3241 taacaaacaa atagcagata acaattccga tattacccca gaatttaaag aaaacttact
     3301 agataatctc caaaacttat ttaaagaata aggggttttt atgacagata aaactatcaa
     3361 agaattagca gatattctag gtgtttcaaa agataaagtg aagtatcaac tgaggaaatt
     3421 acctagtaat tttacctaca aaaaaggaaa tattacctac ctgaaaaaag aagcagtaac
     3481 aacaattaca aaggttttat caggtaatga atcgggtaac ttacctagtg aattacccga
     3541 ttcattacct accgattacc tactcaagga gattgaaact aagaataatc atattgaaga
     3601 aaaagatagg caaattgaaa aacttcaaat agctttagaa acgcagcaaa aattactcga
     3661 ccagcaacaa caactcaccc tacaagccaa tcaacaaatc aaaaaacttc acgaacaact
     3721 ccagctaacc tatgcagaag aatcttcaga aaaagaaccc ctttctgtta ctgaagaaac
     3781 tcaaaaagga caaaacaagg agaaaaaatg gtggcaattc tggcaataac ccaacaattt
     3841 ttattcataa aaattgttgg gttactttct ttttttgctt ttacaagcat agcgacatga
     3901 tctcacgtcg ctatttttta aagagcataa ggaaacgcgg tatcactttc ttacgaaagg
     3961 tgctaggtag gctgtgccta ccacgtttct aagaaaaaaa tttgctatca ctttttcgtc
     4021 attgtggata gcttatgtat agtgtttcgg caaaaaacag ctatacaaat actatatttg
     4081 tatgatatac ataaattata cacaaatgcg aaaggaattc ttctatggac attttagttc
     4141 ggaatattga tccaaaagtt atttcagaaa tagatagacg ttgccaagaa ctcacaacaa
     4201 aaactggcaa aaaatggagc cgtaatgcgt acctaaaagt tctaatcgaa aacgattttg
     4261 accaggcact taggcattac aaaaaagatc aattcgattt attactcgaa aaatttatcg
     4321 atatacaagc aaaaaatact gaaacattga acgactatgt tcatacaaac aaccaactca
     4381 ttgaaacact tatcggagga atataacatg agaaaaactt ctgttcaaaa acacgttacc
     4441 ctttatccca gtcacattga cgttttagat tccatcatcg aaaaaaatcc agatatcaat
     4501 aactactcgg aagccattcg ttttctatgt atgagttatg aacctaatac taatacgaca
     4561 actaccagca accaagcaaa actaaatgcg atgggaaaag aaatttctat tatgtccgaa
     4621 atcattgcag aatttgctga tttatatcta aaagatactg gtgttcttat cggtacaaat
     4681 tctaaagtat atcaagaagt gaaagaaaaa attgaaaatc aactcaatcc ctcccgacga
     4741 aatcaaccca aaaatcgtca aaaagaaacc aatcaaacat tcacttctag aaattttgac
     4801 ccaacaaact ttctaaaaag atgaaaaaga aaccgaaaat tttttctatt tctcagtttc
     4861 ttttttaggg ggcagtcttc cagcaagatt tgcaagttac cggtaacttg cacaaaaaaa
     4921 gaaaaatccg cttgtgcgaa tccttctttt tgcattttgg ggcgctgccc caatctccaa
     4981 atatcggtta tttaatagcg tggtaactca aaaaaataga acgtactctg aaataaaaaa
     5041 agactgctct tccgagcagc caataaaaaa taatgagcgt ttattcttga aaaagcaacg
     5101 cgcttatgaa gcgctgccaa aaatttacca tattttatga aaaataacaa gtttctaaaa
     5161 aggaatcggt taagattcac aaagaatcgt aaacagacaa tagcggaaaa tcaagcttcc
     5221 gaacgtacct tttagctaga ccaatgaaaa atcacaaagt gagcccctgt atcggttgat
     5281 acaagggcta cttggcatac tcgacattat gtctactagc tcgataaata acgattatgt
     5341 tcccaaaaca atattttatg aactataaca aaaatttgtt atcgcatatt gtatatttta
     5401 attataggtg tatatcacgt gaactactca ccacttagct aaacctgacg gttcttaacg
     5461 cttgaagtgg gagcttcttg ggaatagagc atacttgata gcgtatttct ttactaacag
     5521 cggtgtctct tatttaccaa gctatccccg tagttcctac ggttcttgat gattggatct
     5581 aagccaatcc catagaatgt agtcttagac cttcggtcag aatattgata ctagcattga
     5641 tatcacgatc atgatgagta tgacaaacag gacaagtcca ttctcgaatt tcaagagatt
     5701 tcttgccatc tttatgtccg cactctgaac aaatctgact agacggaaac catttatcta
     5761 ctttgatgat ttttcgtcca taccagtcag ccttgtattg taatttagtc acaaactttg
     5821 accaagaaac atcagaaata cttttagcta atttatgatt tcgcaacata ccttttgtgt
     5881 ttaagtcttc aatacagata atatcgtgat ttttgatcat ttctgtactc aacttattca
     5941 gaaaatcagt acgttgattc attacttttt catgcaatct agctactttg cgtttttgtt
     6001 tttgataatt tttagcttca aatagattgg tacctttatt tttagccaat aaagcacgcc
     6061 tagacaattt gcgttgttca cgctttagtt tcttttccat tttggacgtg aatttattat
     6121 tatcaatttt ttgtccatca gaaagaatcg caaagtccat aatacctaag tcaataccaa
     6181 ttgtggaatt agttttaggt aattcgataa tttcttcttt acacaacaaa gaaatatagt
     6241 atttaccgct agaatgacgt gatattgtag cagatttgat aatccctttt ggttgtctat
     6301 gaagcttaat tcttactaat gacttcaatt taggaacttt gatgaattta ctatcaatca
     6361 aagcaactgt accattttga ttattcgttg tataactctg aacaggattt ttcttacttt
     6421 tgaaacgtgg aaatccaacg gatttatccc gaaaaaaatt cttgtatgct ttatctaaat
     6481 taagttgggc attggctaaa gcaaggctat caatttcttt caaaaacgga aattctttct
     6541 tgtatttagc tggtgtcgga aaagtcattt ttttagaaga atcattttta acttcttcat
     6601 acgccttttt tcggtcatca agcattagat tgtagacctt acggacacaa ccaaaagatt
     6661 tggcaaagaa gatttcttgt tcctctgttg gatagattct gaatttgtat gcttttagtt
     6721 gttccataaa gttcacctac tttctattta tgattgtttc cttgattttg gatatacttc
     6781 ttaatcacat caattggtgc gccaccagtt gtcagaagac aaaaactttt agaccagaac
     6841 atttctttcc aaagaaattg tttgactctt ggaaagtcac gttttatcaa tcttgagctg
     6901 gcacttttat aggcattgat gaattttgtc aattctgttt taggttgagc tttgaacata
     6961 atatgaacgt ggtctttatc atgattccac tccactaaag taatgtgata cgattctgaa
     7021 attctttcaa aagtagtttt ggcataatca gatatttcat catcaatcac ttgtctacga
     7081 tatttcgtta ctaaaacaag gtggtaataa agaagaaata ctgaatgatt atttgtatct
     7141 aattccatgt tatatcaact catttcttgt atagactgat tgtaacatgg aacaaaataa
     7201 aaaggcaata cgccttagtt gtcggtcttc gagttaccaa cggtaaccct cataccgaac
     7261 ggcattcatc acccacctat agaggatggg cgacttctgc ctaattctgt taaatttaac
     7321 acaaaggcgt gattattttg aaacccaaaa agaaaattta tctaggtctc ctcttttcct
     7381 tgatgattgg aatttttagt ataggaatta caaataccta tgcttcagaa aattctaatt
     7441 tcaatatcaa ctcccaacca attgaagaac aagcaattaa ttttgcgaaa actgattttg
     7501 aacactccat aacttcaatt cttttaatgg aaaataacac cgaaactgat attaactata
     7561 ctcttggttc gccatttaaa atgctcgatg gagaaaatac ggcaaatagt tctattttct
     7621 ttccagtatt ttcagacgct gataatacga ttaaatatgt ttataccgtc
//
LOCUS       DAFLWQ010000111         7600 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.114, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000111 DAFLWQ010000000
VERSION     DAFLWQ010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.114"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(942..1355)
                     /locus_tag="L1V16_002643"
     CDS             complement(942..1355)
                     /locus_tag="L1V16_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HBN1276926.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1811..2296)
                     /locus_tag="L1V16_002644"
     CDS             complement(1811..2296)
                     /locus_tag="L1V16_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276927.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2435..2650)
                     /locus_tag="L1V16_002645"
     CDS             complement(2435..2650)
                     /locus_tag="L1V16_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBN1276928.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2874..3674
                     /locus_tag="L1V16_002646"
     CDS             2874..3674
                     /locus_tag="L1V16_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1276929.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3693..5561
                     /locus_tag="L1V16_002647"
     CDS             3693..5561
                     /locus_tag="L1V16_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBN1276930.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5554..6045
                     /locus_tag="L1V16_002648"
     CDS             5554..6045
                     /locus_tag="L1V16_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBN1276931.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6033..6587
                     /gene="srlA"
                     /locus_tag="L1V16_002649"
     CDS             6033..6587
                     /gene="srlA"
                     /locus_tag="L1V16_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBN1276932.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6605..7600
                     /locus_tag="L1V16_002650"
     CDS             6605..7600
                     /locus_tag="L1V16_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBN1276933.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2708 a         1213 c         1443 g         2236 t
ORIGIN      
        1 ttgttactat gaataacata ataagaaagt aaagtggatt gatttgagat ctttttatac
       61 ttcaaaaaag ataacaccca actttcaaaa atatgttttg gaagttggga caaacgagtt
      121 aatacatttt aatacattat tttttattca aaaaaaatag cacaatggca aagatcgtaa
      181 gagagatcat aagccccaat gaatgactaa aaagaaaagc agaatcacat gccatatcat
      241 cccatatttc ttcaagaaaa taaataagcg ggaaaaaggg aaggaatagt agaacatcga
      301 tccagcacca tttttttctt cttttgaaat aacataaaac aataaacatg aacgtgcagg
      361 gaagtaaaaa caaagcttta ctcataacta acaaaatacc agctcctttt atttttttct
      421 cccccacatt caaagagtaa caatggtatg tacttaataa tagaaaaatg gatcaacttg
      481 tatgaataac agctgaaaag atctgcacca aataaaaaac ttccagccaa aactgactgg
      541 aagtttattt ttttctgaaa tattctaaca caaatatgaa aaagatggcc gaagctaata
      601 agccgatttc gtagcaaaac aatgagatac cagagtcgta ataataaaat cctctaatct
      661 tatggataaa atagatcatc ggacaagcag ataagagtaa gtatttgtta ggccttttga
      721 ataagtaaaa gaaagcactg gtcattatga taaatggtat ccaaaacaaa agtttactta
      781 agacaatcaa atgatcaact cccatatttt ttaccaagag agatcataac atctttatcg
      841 taaaaacaaa atattttttt gctcattttg aaaatttaaa catactcgtt cttatccaaa
      901 tatataaaaa tcgcccctca ttcatcgaga ggcgataagt tctaatttaa ctcaattttt
      961 tttgtttctt ttggctgata agctgtttta ggtaatacca atttcagcac accgttttta
     1021 aaggttccag tgattttttc ttcatcaaca ttaggaagat agaatgaacg tttgtaagag
     1081 accgaatgtc tttctttccg tacatagttg ccatcttctt tatcttctgt atgggactca
     1141 tgattggcgg agatcgtcaa agtattatct gaatattcaa ctgtcgtgtc ttctttgtca
     1201 cagccaggca tatcagcagt tagtttgtat tctttttcat tttcgactaa atctactttt
     1261 ggataacttg aaacacctaa aaaatcattg aatgctggac taaacacgtc attgaaatca
     1321 gggaacatgt cgcgaatgct aggtacattt gccatttttg atcatccttt caataagtat
     1381 tttttattta tccctattta cgtaataact ctattttgaa aaaaatgcaa gtataatggt
     1441 tagctttgtg aatatttcat ctaatacgat acaaaggcta tctttctaat ttgaaaaagg
     1501 gatcattaaa ataataagaa gaaaatatgt caaaaggtaa aaaagtaaat tcttctatcc
     1561 aaatatagaa aaattgaatc tagaaaaccg cccgacaata aatttcatta actcagttga
     1621 ccgaaaatga agtagatacc aaaaatttat caagagagca agtagagaag tgagtatatt
     1681 cataagagaa atagctgtaa cgaattatta ggttaatgca aatgcttatt tatactccgt
     1741 ataactttct cagaaaaaat gataccaata atgacttgct agtactgtaa atccgtataa
     1801 tatcatctaa tcaaaatggt gttccatttg catctgtcat cgtaatcgat ccttcgggtg
     1861 acactcgata aaaaccaacg cttccagatc ctccttggga acggatttgt ttgctggaag
     1921 ctgtgaacaa ataatctcga tcaatttttt gataaaagct aataacaata tcgtcacttt
     1981 gtaattcgga acggtgggca ataagaaata gaagtgcttt gtcagagttt tctaatggaa
     2041 gagaaggtac agtgctttct tgcatttcag atgttgaaga aatgctaaac gactgaatac
     2101 ttgattggct atgttgcgaa tctacattac cagtagaagt attagtaatg gaagtagtag
     2161 aagtactttt agttgaacca acctcagttg ttgaaatggc tgctgaagat tctttaacag
     2221 aattctttgt tttatatcca caggcagaaa aaagtattac agttcccaac aagcctgcgt
     2281 aaatcccttt atgcatgata gctcctccta aaatagatta tctttattca gtatatcact
     2341 taaacaaaga aaagcagatg gtttaaaatg aaaaaacctt cccaataaag ggaaggttca
     2401 tgaagataat aactttttta ataattatag ctttctaata tctttcatca acttttctag
     2461 taatcattgg gaaaaatttc aagcagtaga tcgcacaaat acctacgacg atataaatga
     2521 tcttcgcaaa aatagttgtt gaaccaccag caatcatagc tactaaatca agttcgaaca
     2581 agcctaccaa cagccagttc aaccctccca caatcaataa agttaatgca atagcatcta
     2641 aagttttcat tagaattctc ctttcttaaa tgataaaaca attatatatc aaaaagagaa
     2701 acattgctta tataacgctc aggaatttta gcaatctatg caaaaagatg aaaatttttt
     2761 ttgctcttcc attagtacac attttttagc tgaagctgta aatttcatgt cttaattttt
     2821 tttagtgagc ttttatactg gatttgtaag aaaaaagaag gagaggatca catatgtcgg
     2881 attggttgga tattgcagga aaagtagtaa ttgtaactgg aggttcctca ggaattggaa
     2941 gaagtatcgt cgaaaatttg ttgaagcaga atgcacaagt agcgaatttt gatgtaactg
     3001 aatgccgtat acagcatgaa aacctactat ctttaaaagt cgatgtgtct tctaaaacgg
     3061 acatagaaga agggatatat aaagtaatga aacatttcaa gacgatcgat ggtctagtca
     3121 ataatgcagg aataaatatt ccttctcttc taatagatag aaatcatcca aaaagcaagt
     3181 atgaattatc agaacaagtt tttgataaga tgatcgctgt caatcaaaaa agtgtatatt
     3241 tgatgagcca agcagttgga agaatcttgg tgcaaaaggg atcaggagtg atcgtgaatc
     3301 tttcttctga atcaggattg gaaggatcag aaggacagag ctgttatgct gctacaaaag
     3361 cagcgatgaa cagttttact cgttcttggg caaaagagtt aggaaagagg aatgttcgtg
     3421 tggtaggtgt tgcaccaggg atactggaag aaaccggttt gagaacacaa gaatatgaag
     3481 aagctctttc ttatacgaga ggtataagcg tcgaacagct gagaaacggt tacagtcgaa
     3541 caagtacgat ccctctagga aggagtggta agctgcaaga agtggcggat ctagtctgct
     3601 attatctttc agaaagatca agttatatca ctggagtcac gactaatatt tcaggaggta
     3661 aaacaagagg ataaaggata ggggggacgc acgtgacgct agtaaacaga tggtaccaat
     3721 tattgaaatt actagtcact cacaagaaag tttcaatcca ggaagtgcaa aaagaaatca
     3781 aaaccagtaa tcaaaccata aaaaaagata ttggggagtt gaatgaagaa attgccggta
     3841 ttgcaaaaat catccaaaaa aacaaacatt ttgaacttga aatttatgat tttgattttt
     3901 ttgatgagat catgcaagga aaattgaaaa cagccagtga tttcaattcg gcatccaaaa
     3961 gaatcgctta tttactaaat aggctgatcg aaacagagga tttcttacgt atggatgatt
     4021 tgtctgaaga agtcggtgtc agcagaggaa cagtggtcaa ggatctaaag acattaaaag
     4081 agatgatcaa tgattttgat gtaaagatta caggcacacc aaataaagga ctaagaataa
     4141 taggagatga gctagaatta cgactacttt tattttattt tgtttctccc tacttttcag
     4201 agacgaaaac agaacagttt ctagaagaaa aacaagcaat caaacatttt cagaagaaga
     4261 cgaatgctag taaacaagaa atcacccttt taacgaaagt tatcggtatt tctttgaata
     4321 gaatctctag taactatctg ttgaagaagc ccatcaatcg ttacagtggg tgttttgaat
     4381 atatccaaga attcaatgaa ctgatcaatc agttggaaga aatctatgaa ctaactttga
     4441 gccaatatga aaaagatttt atcagttttc ctttgaacat catcaacaca agtataacga
     4501 tgataaggaa agctaactct gatttgcgct tatatttcga ccccatgatg atgcgtattc
     4561 gacgattaga tctcattgat ctggatgagt ccttcttata tcaagagatg aaacagcacc
     4621 tctctttatt gataaatcgg gtaatttttc gttatcgatt gactgattta ttttatggtg
     4681 agatagaaaa aaagtatcct ttttcttacc aaatcgctag cgaatgcata caagcattag
     4741 aagctatctt gcaacataag atctctaaag tagagatcag ctacctaacg ttgtatttgg
     4801 agttagcatt tcgatatcaa aaagagcatt tttcctctaa aaaagtagcc attgttcata
     4861 cgacaggaaa aggaacagca ttaatgatcc aaagacaaat caaaaggata ttggggaggg
     4921 atatacaaat aacacatgtt tcagaagaac aatatgaaaa agtagatcta aacaaatatt
     4981 tcgctgtttt tacaacgatt ccgttaaaaa atgtaaatga agagacaccg gtgatccatt
     5041 tgactaatct ttttgatgac tcttggttaa gggcacaatg gcaaaaagca aaaaaaaagc
     5101 gattagccgg gtttcattct actgtttttt tctatcaaat atggaaagaa aaaaagacgt
     5161 atcaagaata tttaaacaaa ttagtcgctc ctttgatcag aggctattat gtggatgaag
     5221 aatttgaaaa aaggatcttg aaaagagaat atcagcaaag cacatttgtt aacaaagaat
     5281 ttgcttttcc tcacacaacc aaccagctat ctcaacacat tgttttatca gtagggctaa
     5341 taactgatca aggtttagca gaaacaggag gaaatggagt tattttttta tttgccatac
     5401 ctgaagaaat gacggctgaa gttgagaatg aattatttga gctatacgat atcctatttg
     5461 aactcataaa aatgggaata gatgagttta ttgaattagc accgacacaa gaatcatttt
     5521 taaaactaat caaaagtaaa ggagagagac ttcatgaatg atatgtatct attcatagtt
     5581 ttcgcagctt cagcttatgt gctgcaagca gttatcagtt ggaagcaact aaagcatttc
     5641 aatcaaacat atagcgaact gcgaagaaaa ggaaaagtag cgattggtaa acgacctggg
     5701 aaaatccgtt caggcacgat tgttatgcta gctatagacg atcatgatca agttttagaa
     5761 gtcagaaaaa tgcaaggggt tacatctttg gcaaaatttc attcattacc tgtctatgcg
     5821 ggtgaagata tccattacat cgatcgttac catccctcag ttcgagcgga agatcgtttg
     5881 acacaagcag ctttagaaaa tgccagagaa gtatacttac gaatagaggc aggaaatgaa
     5941 aaaagtgaac aaccttcatt gccttttatt gctatgctca ataattttcg gatatggaaa
     6001 agtacgatca aagaaaaaag gagtgacaaa cgatggatat cataacaaaa tttgctgagg
     6061 gatttatgag gctgttccaa acaggtgcag aaacattcat aagctggatg acaggaatcg
     6121 taccagttgt cttgatgctg atggttgcaa tgaatacgct gattgctttt ttaggtgaag
     6181 accgagtaac gaaagtagcc aaattatcag cgaaaaatcc gcttactcgt taccttgtgt
     6241 taccgttctt atctgctttt atgttgggaa atcctatgtc atttacaatg gctcgtttcc
     6301 ttccagaata ctacaaacca agctattatg ctgctcaagc tcaattttgt catacgagca
     6361 atggtgtatt cccccatatt aatcctggag aattgtttgt atggatgggg attgctcaag
     6421 ggatcgaaac cttagggcta aattcgatgg agctggctat ccgatacttg cttgtgggac
     6481 tgctgatgaa ctttattggt ggttggataa ctgattttac tactggattt gtatgcagac
     6541 agcaaggaat cgttcttagc aaaaaagtag agctttcagt tgattagaga aaggagagtt
     6601 ttaaatgtat ggtgatatta agatcgtaag aggaaacggc gggtatggag gtcctttgat
     6661 tattaggccg acaaaagata aacacaagtt catctatgtc acaggtggag gtgagaggcc
     6721 aatgatcgta gataaaatag aagaactgac aggtatggag tctatcaatg ggttcaaaac
     6781 atcaatacct gatagtgaaa tcgcgcttgc aatcgttgac tgtggaggga ctcttagatg
     6841 tggaatttat cctaaaaaag ggataccaac catcaatatc gtttccacag gaaaaagtgg
     6901 cccattagca caatatatca ctgaagatat ttatgtttca gcagtagggt tagaacaaat
     6961 acagccacta atggaaactg atgataacaa agaaacagta aatactgcat ctccagataa
     7021 aaagtacaaa tatgatactt ctaaaaagat aaccgagcaa aaagcagagc agcaaaactg
     7081 gatagcaaaa attggaatgg gcgcgggaaa agtagttgct acattcaatc aatcagcaag
     7141 agaagcagta gatacgatga tccggacagt gatccctttt atggctttcg tttccctttt
     7201 gattggtgtg atacaaggtt ctgggatcgg taatgtattt gctaacatta tggcaccttt
     7261 agcaggaaat gcagttggat taacaatcat tggctttatt tgttcactgc catttttatc
     7321 tcctttgctt ggtccagggg cagttattag ccaagtgatt ggaacattga tcggtgtaga
     7381 gattgggaaa ggaaatattc ctccccaatt agcattaccg gcactatttg ctatcaatac
     7441 tcaaaatgca tgtgatttta ttccagtcgg tctaggtttg gaagaagcaa aagctgagac
     7501 agtagaagta ggtgtaccat cagttcttta ttcaagattt cttaacggca tcccacgagt
     7561 tatcattgct tgggtagcaa gttttggatt atatagctga
//
LOCUS       DAFLWQ010000112         7537 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.115, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000112 DAFLWQ010000000
VERSION     DAFLWQ010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.115"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            107..1248
                     /locus_tag="L1V16_002651"
     CDS             join(107..335,335..1248)
                     /locus_tag="L1V16_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBN1276934.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
     gene            1483..1935
                     /locus_tag="L1V16_002652"
     CDS             1483..1935
                     /locus_tag="L1V16_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276935.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            1949..2638
                     /locus_tag="L1V16_002653"
     CDS             1949..2638
                     /locus_tag="L1V16_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276936.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            2763..5114
                     /locus_tag="L1V16_002654"
     CDS             2763..5114
                     /locus_tag="L1V16_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HBN1276937.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            5194..5589
                     /locus_tag="L1V16_002655"
     CDS             5194..5589
                     /locus_tag="L1V16_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276938.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            5914..6531
                     /locus_tag="L1V16_002656"
     CDS             5914..6531
                     /locus_tag="L1V16_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1276939.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            6572..6871
                     /locus_tag="L1V16_002657"
     CDS             6572..6871
                     /locus_tag="L1V16_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HBN1276940.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            6905..7072
                     /locus_tag="L1V16_002658"
     CDS             6905..7072
                     /locus_tag="L1V16_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBN1276941.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(7117..>7537)
                     /locus_tag="L1V16_002659"
     CDS             complement(7117..>7537)
                     /locus_tag="L1V16_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1276942.1"
                     /translation="SLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNELLD
                     TAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRLV
                     FKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT         2594 a         1138 c         1502 g         2303 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc gtagaatcta actactaaga aaaggacgtg tccacgatgg caaaagccaa
      121 gaaaaaattt gatgaagact ttaagaagat gatcttagat ttaaaccagt ctggccaatc
      181 ggtcgaagaa ctggcagcgc aatatggtat cgctacacaa acgatttatc gttggaagaa
      241 gcttcataca aagaatgtag caaccggcat gactgaggca gaaatcctag cgatgaaaaa
      301 ggaaatggcc cgcatgcagg aggaaaacac tatcctaaaa aaggctttaa ccatattcgc
      361 tcaaaagtaa aaatgagtga tgtcttcgaa tttattcaat caaatgttca tgatcatgac
      421 gtaaaacaaa tgtgtaccgt tttggaagca ccgaaatcca gctactatga ctggaagaaa
      481 aagaaacctt ccaagcgcca atcagaaaac aaacgcttaa accgcttgat ttcaggaatc
      541 tactttgaaa acaagggtat ctatggtgcg cctaaaattc ataagattct tgttggccgt
      601 ggcgagacct tgtccttaaa gaaagtacaa atactgatga gaaaattagg cttgcgttca
      661 gtcaccctca agaagtacaa gcctggcaaa caagcgaaag ttaaaagtga aggacgtaaa
      721 aacctgttaa accaagattt taccactacg tcgatcaatc aaaaatgggt gacagatatt
      781 acctatattc ataccctaaa agatggctgg acctacctct ccactattca agacctccac
      841 acaaagaaag tcatcggttg gaagtttggc aagcagatga cgaaagaatt ggttatcgaa
      901 acccttgaca atgcgctctt aaaccaaaca ccctccgaga acttgatcat ccactcagat
      961 ttgggttctc agtacactag cgaagcctat gaggcaaagc tgaatgaatt gaacattcgg
     1021 cactccttca gtcgtaaggg ctgtccctac gataatgccg gtatcgaatc gtttcacgcc
     1081 tcactcaaaa aagaagaagt ctatccatca aaagcgtatg aaaactttga agctgcttat
     1141 ttagcgttat ttcaatacat tgaaggattt tacaatcgca agcgaatcca tagtagtatc
     1201 aactatttaa caccaaatca gatggaggag ttggcattgc aagcttagtt cctagctacc
     1261 acttacattt ttttggcgag atttccacag ggtttcaact tcatcgcttc gatcagcggt
     1321 caaacggttt tggtttgacc gctggtcgaa acgatgagat actcacccgc tggaatctcg
     1381 aaaaaattct cacaaatcgt gtccgaggta ttgactcaaa tccaccaatt atcttatcgt
     1441 agatatatat tataaattta ataagaaagc gaggtgagaa tcgtgaaaaa aacgatacta
     1501 agtatttttt cagtatttac aatattaatt gggggctatt ttcttttgaa tttagattct
     1561 gttaattcaa acgctcaaat aaaagatcaa agagtagctg aacataataa taaaaaaatg
     1621 agtttgacca aaaatatcta ttctatgtca gatgaagaat tgtataaaga atttggtgat
     1681 ttatccgggg aacagttaga agaaagtatt ccaggaatta gtgactcaga taaaattgtt
     1741 gtcttgtctg ctggtgggca attaatggga gatggcaaat ccgaattagt tagttataaa
     1801 caaaatcaca gacagtttat tgatgttaat actgattcca acgctatttc gattaaggat
     1861 ctaaaagagc ttttaaatag taaaagaaat gaattaaagc agataaaaga aactaattca
     1921 gtggaattag agtaaaggaa gattcattat gaaaaagatt tttggtgttt ctgttgggct
     1981 acttatgatg ttaacatttg gaaatgcagt atatgctgct gagaaagaag ttatttcaga
     2041 tccagagcag tacgcctcac gatactttgc tgattttgaa gaagaagata aagtacttgc
     2101 attgccagaa ggtggttttt taaaagggga agctaaaatt gtatctatgg ataatccaga
     2161 tataattcaa ggttcatata attcagaaac tgatcctgct tcagtttcag tgacagaagc
     2221 aaaaaaaatt gttgctgaaa aattcaaaaa tgatattgaa actactccaa ttatgcctcg
     2281 aggagcattt ccacccgatg ttggtactag cggacacctt cttgtactag caggaggagg
     2341 aagctataaa tcacagccat ttagtggtgc gggatggcgt tttggaggta tgggtgtaaa
     2401 accagctgat ggtacaggca actttttacg ttggaaatcc tacattgacg atggaagagt
     2461 aggaaatgta aatcaagcca acgcaactaa atctggttct attcaaggaa tggcattgta
     2521 tgctcgtgaa ggattcaaat actttgcacc aaacgggcct ggttggacaa tgaatatagg
     2581 tatttattac acttataatc ctgttgcagg tacgtattat gttgttcaaa atatttaata
     2641 aaacagcaca aagagatttc tttgtgctgt tttattattt ttagttgttg acaaacacta
     2701 aaatataaaa tataatcaac acataaacga acgtatgttc ggcaagaaag caggggattt
     2761 ttatggatga gatggtttta agtactcaga aatggctaaa caagaaatac agtaatgtta
     2821 cagggtttga taaggttcca gaaaatgggc gaacagggtg gcctacaatc tatggactta
     2881 ttgaaggact acaagtagaa cttggtatta ctaatctagt agctaatttt ggacctacca
     2941 ctgaaaaaat gtacgataat caggttactc ctaaatgggg caaaaatcta cctaaaaata
     3001 ttgtatttct tattcaaggt gccttttggt gtaaggggat taatccaggt ggcttcgatg
     3061 gggtatatac tccatattta gatactgctg taaaagagtt gcagactgat gcagggttta
     3121 atggaagcgc tgtaactgga gttttggatg cgaaatgggc caaagcgtta tttgatatga
     3181 gtgcttttgt tcttgttccc ggcggagata gtaaaattag aaaaatgcag caatggttaa
     3241 atgtaaatta tttagaatac acgggaataa tgccttgtga tggtatttat caaagaaatt
     3301 caaatcaagc attaattttt gcattacaag ctgaactagg atattctccc agtgaagcaa
     3361 cagggtctta tggtaatggg acaactagta aaacttatcc tgtgtctgaa ggtaactcgg
     3421 gaaactatgt aagaataatt caatatggat tatatgttaa tggttatttt gaagacggta
     3481 cattcgatgg tattttcact aaatatatgg gtttagaagt actggcattc cgaaaattta
     3541 tggtattgcc tgaatatact gaaatagcag atgttgttgt aataaaagga ctattgtcta
     3601 gcgctggaga tattagaaga tctgcagatg gcgcagatac ttctacgcaa ttaactagat
     3661 ctcaaatcca aacattggtt gataatgata taaaaatagt tggtagatat cttactggta
     3721 ctgttggaat tggaaaagat gaacgaaata agtatctaac tacagaggaa ttgaataata
     3781 ttttttctaa aaatttatct gtgtttccta tctatcaaga tggaggtgca gcattagctt
     3841 attttactta tgatcgtggc ttatcagatg gtaagaaggc tatagatgca gcaaaaaatc
     3901 taaatatacc attaacaaca gttatttatt ttgctgttga tctagacatg ttaggggaag
     3961 aaattcttgc atatgctgga gaatatttta agggggtatc tgctgtaatg tcatatagcg
     4021 ggtatcaaac gggtgtttac ggaacaagaa atgtttgttc tcaaataatc aataacgggt
     4081 atgcttcgtt tgcatttgtt tcagatatgt cgactggtta tagtgggaat ttaggttttc
     4141 ctatgcctag acaatggtct tttgatcaat ttgttgaatt taccatagga agtggcaacg
     4201 gagctgttgg tatcgattta atcgctacat cgggtagaga tagcggattt aatgagttat
     4261 caaatgatac taataatgat aattacattg ccaaatacaa tcagaaggtt ataaatcaga
     4321 tggtacgtgc gtatcaatat ctatcacaag ctggtcttga taatccttgg aaccctcatt
     4381 tgacatttta tagatatgta aattattctg gtttgtcatg ggacatcatt tcttctcctg
     4441 taacagagca tgatagaaaa atttatgatg aatataggaa taaattaact aatagcgagg
     4501 gcctgtataa ttattttata gatcctaata ctggttcaat aataggtttg cctcacttaa
     4561 ttgtgacgtt acaatcacag atgtttctag ccgacacaat caatgatagt gtttctgact
     4621 ttgcaggttg gttaggagat ttaatgactt gctggggtga agttaagaaa ttaggaatac
     4681 aaatggagca aggtgtattt gcattagtag gtacggctgc aggtggaaca tttagtctag
     4741 aagatttata ccaagatgtt gacgcggtaa atgtttatac cttagcaaaa agaaattctg
     4801 attcaacagc tttatcggct ttaaaaacgt actattgtga taagggtgct attgatagat
     4861 ttaatcaatt tgttaagaac agatttggtt cttcagataa aatcgcttca gtaacaaata
     4921 gtttattaga aaatgacgaa acagttgata tcttaggtgt agggataatt tcatttttca
     4981 ttgataaaat agttaataat tcacttggga cagattttac ttatcttgat tttattggag
     5041 atgaggggaa agttgcaaat ggattttctg aaaaaattat tcaatttcaa gaaaatagaa
     5101 gtaaacttaa ttaagaatcg tttactattt aaacagtgtc cttttccttt ttaaatatat
     5161 acgataaaat aagtatatga attgtaaaag gacatgatga ttatggaaga aatagaatgg
     5221 aataatctga ctcaaaataa taaaaataat tctggatgtg gaattatctt tatgtttgtt
     5281 atagttttgg gaatagtagt acttttaata actgtcaaga tagtagatta ctttgcgaat
     5341 actcctgaag aacaaataca gagaaaactt cctgagtttg aaagagtacc accttatgat
     5401 ccaagagata attcatttca agtaaaaaaa ttaaaagagt ctccaaatga aatgtggttt
     5461 gaagttacag ttgaatcaag cgacttcaaa gaaaaaaaga aagaatacaa ttatattgta
     5521 aaggcaaaag tatcaaaaag atttattttt aaccctaaat tagaaatata tagtgttgta
     5581 atagaataat agtgttaaaa aaattgtaaa agttaaagaa gtcaaattct gatgtgaaaa
     5641 ataaaatata ccatggaaga cataaaagaa aaactggata actagtttat ttaatggcag
     5701 accgttaagg cctgccattt ttatgtattt tagcggaata aatataatca tgcgggagtg
     5761 taaacttact gtttcaaaaa gtatactttt tgacatgcct tgattttctt tgtttatgta
     5821 tggcataata accacataat acaatttgaa acgtttctga tttaatctga ttgttttgaa
     5881 acaattttag tgaaaaaagg gtagataaaa acgatgagaa aattttttta tatccgggtc
     5941 agtagttatg atcaatcgat cgaacgacaa ctgatttccg cgaaggaatt aggaatccct
     6001 gaagaatata tatttgtaga aaaagccagc ggcaaagatt ttaaacgccc tgaatatcaa
     6061 ttaatgaaac ggatgtttcg aaaaggagat ttactctatc tacaatcatt agatagacta
     6121 ggcagaaata aacaaatgat tttagaagaa tggcgagaat taactaagga aaagcagatt
     6181 gatatttctg tgttagacat gcctctgtta gatactgcta gttacaagca actagatggg
     6241 ttagagacgc ttatctctga cttaattctg caattactca gctatatggc cgaagacgag
     6301 cggaaacgaa ttaatagccg gcaaagagaa ggcgtagaag ctgcgaaaca aaagggtgta
     6361 aaattcggca gaaagaaaat tgctttacct cctgaatttc ctgcgatcta ttctgactgg
     6421 aaagcaggaa agataactgc agtctatgct atggatcaat tgggcatgaa acgaaatacc
     6481 ttttatcgac gggtgaaaga atatgaacat accttgcacc acttttcttg atagatataa
     6541 cagctattag acgggaaggg agagtttgaa aatggactta acgaatcaaa gggtcgtttt
     6601 tactggaacg ctgcagcaaa tgacacgaac ccaagccatc ggtttggttc actctttaaa
     6661 cggccattgt caatcaagtg ttacttcaaa aacaaatttc ctggtttgtg gtcagtattc
     6721 taagtcgttg tttgatgatt ctctctatac aaaaaaggaa caaaccgcgc gggacttgat
     6781 tgcgttaggt catgagatta ccattttatc agaagtcgaa ttttatgcgt taattagtca
     6841 acagttgaaa gaatggcaac ggtatttata atcgttagta aaatttacaa ggaggaaaat
     6901 ttttatgaag cgaaaatctt atgatcgttg gggcattgaa ataactagtt ttaatcgaaa
     6961 tattgctttt cacgtggagt gtgactgtgg ggaattagca aaaagtgttt atcaaaaaaa
     7021 ttacttttac tgtcctaaat gccatcgccg atacggggta catggaacat agaaacgaaa
     7081 tagtgcggta gaaaagcgaa tgaatgtagt atatttctac aaatcattcg ctttctttat
     7141 tttataaata gttggtcgag agatcccgtt ttcttttgca atctctgcaa ctggaatgcc
     7201 ttgctttaac atgtccacca cggttttaaa aactaagcgt ttttgcggat ctgttgagtt
     7261 aatagaatac tcgattggtc gtcccttata tcggccggct ttttgagcca ataatactcc
     7321 ttgccgctga cgttcacgaa ttttctcacg ctcgttttgt gcaatataac ttagcagtga
     7381 taaaaacata tcgaacatag cggtatccag gagttcattt ccagtattaa aatctaaaaa
     7441 ctgtgcatct aatattttta acgctacttt tttctgtttc ataaaagcaa ctgtattttt
     7501 tatatcttca taatctcttc ctaaacgatc tagtgat
//
LOCUS       DAFLWQ010000113         7490 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.116, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000113 DAFLWQ010000000
VERSION     DAFLWQ010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.116"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..645
                     /locus_tag="L1V16_002660"
     CDS             <1..645
                     /locus_tag="L1V16_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBN1276943.1"
                     /translation="KINKITHQENRQKNLIVQNLNYGTNQYSVDSSKFELCDTSMKTR
                     DKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLSTKNNKLDEELIETFIEENLL
                     KQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAEKEQKIQLKIIYEICNNKYFV
                     DHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNKALELIELQISEGIDKQ"
     gene            721..939
                     /locus_tag="L1V16_002661"
     CDS             721..939
                     /locus_tag="L1V16_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276944.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            926..3604
                     /locus_tag="L1V16_002662"
     CDS             926..3604
                     /locus_tag="L1V16_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276945.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGF
                     KTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKSR
                     RRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSCN"
     gene            3595..3792
                     /locus_tag="L1V16_002663"
     CDS             3595..3792
                     /locus_tag="L1V16_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276946.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            3796..4407
                     /gene="mobC"
                     /locus_tag="L1V16_002664"
     CDS             3796..4407
                     /gene="mobC"
                     /locus_tag="L1V16_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBN1276947.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            4392..5783
                     /locus_tag="L1V16_002665"
     CDS             4392..5783
                     /locus_tag="L1V16_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBN1276948.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            5999..6313
                     /locus_tag="L1V16_002666"
     CDS             5999..6313
                     /locus_tag="L1V16_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276949.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            6306..6800
                     /locus_tag="L1V16_002667"
     CDS             6306..6800
                     /locus_tag="L1V16_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276950.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            6868..7182
                     /locus_tag="L1V16_002668"
     CDS             6868..7182
                     /locus_tag="L1V16_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276951.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            7281..>7490
                     /locus_tag="L1V16_002669"
     CDS             7281..>7490
                     /locus_tag="L1V16_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBN1276952.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDL"
BASE COUNT         2886 a         1012 c         1439 g         2153 t
ORIGIN      
        1 aaaattaata agataaccca tcaagaaaat agacaaaaaa acttgatagt tcaaaatttg
       61 aactatggaa caaatcaata ttctgttgat agttcaaaat ttgaactatg cgacacatca
      121 atgaaaacaa gagacaaaaa caattttgct gatagttcaa aaaatgaact agaattatat
      181 aagtcttata aagatagtaa agatattaaa gaatcacata atgatgatct tcttgaatca
      241 ctttcaacta aaaataataa attagatgaa gaattgatcg aaacatttat tgaagaaaat
      301 cttcttaaac aaatatgggg agaaagtatt gtgaattgct taaaactggc tagcaatagt
      361 gattatcgtc aattcgacaa ctggtacaaa aaattcaaat atgcgattag atctgctgaa
      421 aaagaacaaa aaattcaact gaaaattatc tatgaaattt gtaataacaa gtattttgta
      481 gatcatgtta gagaacagct atcaatgact ttacgtgact tgatacgaag agcaaaaaca
      541 gatcatcgta tcaaacaaaa agacgattat atctttgctt ctctaaaaaa taaagcgtta
      601 gaactaattg aattgcaaat cagcgaagga atagataagc aataagaata gaattgagtc
      661 aaatgaaatg gaggggtatc tccacttcat ttgagaactt tgaatatagg aggggttatt
      721 ttgattaaaa atcgtttaat agatcaagtt tggtgtctag atcaaaatac agatagtctc
      781 gaattaatcg agactatttg cttcaacact atagttctcg atttaagagc tgaaaatgat
      841 aattgtgtaa ctcatgtcat aattaatcaa aaaatggctc agaagctctc tgagagcctc
      901 agaaaatggg ctaagggagg taacgatgaa aataattgaa aaaaagattg ccaataaaaa
      961 aataaattgg ttggttgtta attttcttgt tctgatagct atgattattt ttacaagtaa
     1021 tattgctcat gcgagtattt tcaattggtt tgatgacaca aaaagtcaaa cagagttttt
     1081 gaataattct ctttatagac cttacctaaa aaagtacaat ggagatttcc ttagtcagtt
     1141 cgggatttgg ctcggatggg ctgtggtaaa aggcatgttt actgtgacag attcgattca
     1201 aaatatgatt ccagatgtgc tggatttgtt caatttcatt gaaagtacag ggctaaataa
     1261 tgtttatcaa tcagccgtaa atacaattgt cattggatta atgatccttt cattgatgtt
     1321 tgttggttac aaaatgatta ctggaaaagg aacagtggat ttaaaatcgg ttggaatgaa
     1381 cgtagtgatg tctatagcat taatactttt aatgccaacc atgatttcta gtggtattca
     1441 atttgctaaa acattttata aggactctac tacgattaca aattcagatg acggagtcgc
     1501 ttggtcattg ataaaacaag gagtaacaga tttagcatat attaataaaa cagatcagta
     1561 ctcaagcatt gataaaacgg aggatcgaaa taatttaaca cgaaaaaatt ttcaacagac
     1621 ggatctcaca caagtgttaa cggataaagt gattgataaa ttggaaaaag aaaatccaat
     1681 tgcggacaat cttcgttatg aattagttga aaattctaat aatgaatttg ttgctacaaa
     1741 gttttctgac aacttcttat caacattttc tgatagcttg aaatcaggct attaccgata
     1801 ccaagcaaat ctatggggga tttcaattgg gttgacagcg ttagcaatcg cctatgtgtt
     1861 cagcgcgttt gtgatcatta cagcaatact agaacttgca tttaaacgtg tgttaggtgt
     1921 tcttgttttt gcaacagata ttgagacagg acagcgttca aaagttgttc tatcagatat
     1981 tctacaatgt tacttaactg ttgggtttca aggatttggg ttatcaatgt ttgctatgtt
     2041 tatcaatttt ctgaactcag gacaaggtat ctcaacaaat atttttataa aaacaattgc
     2101 ttatatctgt gccgtttttg ttttaatcaa aggcagtgga acagtcatga gatactttgg
     2161 tgttgatatt ggactcaaag aaggctatgg gcaacttgct tctgcttttg gaatgggcgc
     2221 aatgctgttt agaaaaggat caaatggatt taatcgtgct aaaggaagcg gagaaggaga
     2281 agatcgaaaa ccagaaaaga atttcggcga aactctatca aaaaaagctg gcaaaactgg
     2341 aagagctttg ggatatgccc atgaacgtgg attatccggt ttagcttcag atggagctac
     2401 aatggctagt gaaagagcaa caaaaccatt taagagtatg cgtgatatag ctaatgatac
     2461 caagaataag tttaaagaag gtttagatga tggtacagtg tccgctatta ataaaaatag
     2521 caaacctatg ttagctaaaa ataaagaaga tgaaactgga aaatatgctg attccgtgcc
     2581 aacacgtctt tcagatagaa aagatggtgc taaagttgaa aatgccgata gaattatgtc
     2641 tagttctgaa cgtatgcgtg aagcaatgaa aaataatgct gaatcgaata ataatcctgc
     2701 aagcgcaatt cagcaaaaag tccaacaaga tattgaagaa cgtaaaaatg ctatgcacgg
     2761 tcaagctaag tctgctgaag aattaattaa tcagaagcgt catgaagcga aatacacgcc
     2821 tgaagcaatg aatcgcgagg aaataatgtt aaggaaacgt gtagaagggc ggacaggcgc
     2881 taatattgac ggaaaagaag cgttgaccaa agaaagaatt caagaagcta aaaattcaaa
     2941 tacaggatta gaaaaattag tcaaagaaaa tccacaaaat tctacaagta gtcatggtgg
     3001 ccgatcagta gatgtccgag aaaatattca aggttcactg aatggtcatg ttggacggaa
     3061 tgttgatgta agagagaatt tacaaagttc ttcaaatgct caaggtacta agacaattga
     3121 tgttcgagaa aatctgcaaa gtagcagtac aagtcaacca aaaacagtag atgttcgaga
     3181 aaatgtacaa aattctacaa gtagtcaagg gtttaaatca gtggatgtcc gagagaatgt
     3241 gcaaggtagc agtgcaagtc aaccaaaaac agtagatgtc cgagaaaatg tacaaagttc
     3301 tacaagtagt caaggattca aaacagtaga tgttcgggag aacattcaaa aagatagtgg
     3361 agaaatgaaa gaaaaaacac aaaaaatcaa tatcgttgaa gacagaaagt cagcgaaaaa
     3421 atttgattca aatcatgaaa cagtgattat tgatagtgaa atccgtgaaa atgataaggg
     3481 atcaaaatca agacgaagat tcacttatga agacaatgag ttattcagag atacacttaa
     3541 tgatcctaat ccacttttcg ataatttatt aagaaataaa agggggggat tgtcatgcaa
     3601 ttaattctaa agattagtac gcatgatttc ttagaacttg acgaattatg tgaatcagta
     3661 aagaacgcaa caaatgaaaa aatcacggtc actaattata ttgaactgat gattcaagaa
     3721 gaattaaaga tgaaaaatga aatagagagc aatttcaaat gttgctctct agaaaaaaat
     3781 gtgaggggat aatcaatgga tgataaacaa aaaatgtacg aaaaaaatcg caaacatagt
     3841 gaggccttaa attttcgtgt cgataaaaag acttatcttg aactgacatt gattgcaaaa
     3901 caaaggggaa tttctagagc agacgtttgc cgtgagcggt taaagggact caaatatgaa
     3961 ccgccgttgt tagctgaaga tgatagggta gttttaacca aacagttaaa tcaaattggt
     4021 aacaatttga atcaagcggt aaaggcatta aatatcattg ctaaatattt tagagaagaa
     4081 tctgaagata aaaaagaaaa gagcctacat tttagttttg atgctagccg ttacaacatt
     4141 tttaaagatg aacttgcgaa tagcatagca aaaaagttga tgattagtta tccagatgac
     4201 atttttttgg agtccaatcg gagtgccccc tcttttttta aattatcaga agtagaaaaa
     4261 gaatatttcg aatattggat agaaaagcaa actagaccgg gtacgaaaga agagtattcc
     4321 caaaaagttg atcggaattt aattcactca attcagatta ttgcaagttt aaaagatgag
     4381 gtgaaacaac tttgggagct actataacat cgaaaggacg caagaaaaat ttatcctcgc
     4441 tattacaata tgcagctaat ccttcaaaaa aagaaaaatg tgttgcagtc tcaggaataa
     4501 attgtagtga tgatagtgag gaagcactgc aagaaatgaa tttagtacgt accaagatga
     4561 ataaatctaa agatatagca caagcgtttc atgttattca ttcgtttgat aagagtactt
     4621 ctaaagagtt aagtattgat aaaatgcacg aaatagctgt cgaatttgca gagaaagctt
     4681 ttccaaattc gcaaatcatt gttgcaagtc acaatgataa agatcatttt catagtcatc
     4741 ttgtcattaa taatattaac atggaaacat gtaaaaggtt gcgtattgac cctaaagatt
     4801 tagaactaat gcgaaaaatt aacgatcaag tcctcaatga acatggtctt gaatcagtga
     4861 ataatgagta ctatgaaaac ttagaaaaga gaaccaatct ttattcaaac gatccttcta
     4921 agatgaaata tggaaaaatt aattatcaag agtttgtgca aaatgcgatc gaagcaacgt
     4981 tggaaaaatg cgaagtgaat tcttttgaag atttttcgga tcatttggca aaagaatata
     5041 acattgaagt ttatcaattt tcaaaaacaa ataacaaact tggctatgtt ctttacaaac
     5101 aaggtgtaaa tttctatgag cgtagaggtg agttaattac tttaggaaga gataaacaat
     5161 ctagaaaaga aaaaagtcag tatgtcgaac gtacttttag tgcaagaaag ttagggaaaa
     5221 gatattcatt tgaatctgtt tctgaacaac ttgaaaagaa tttagaagaa tcacatataa
     5281 aaaatttttt taatatggaa agagagcaag ttatgtcgct aattagtgga gtaaattaca
     5341 aaactggtga gttaaatgta ccgtttgtgg aattagattc catcgcacaa aagcaattta
     5401 gcgaccgtga aggcgatgaa aaattcatta aatatgatga cttcttgcga gaggtagaca
     5461 agcattttgt aaatacaatg tctttagaag atgatcaaga atacacgatt aaacttcata
     5521 cggatgtgaa tcctcaaact ttacgtagtg cgaaaagtaa aacaatttct attaaaaaga
     5581 ctgatcagaa agagttattt ctaccggcaa agggttttga aaattgttct catacacctt
     5641 ctgctaaaca gattcactat caaatcagtc gcataatgaa tgacgatgta aaaatgtatc
     5701 gtgctaaaaa ggattatgaa ttcacacaac aaatgattga aaatcagcaa aaaaggcaac
     5761 aaaattttga aatggaattc tgaatgggct tgttagtgga ctttccagtt ttttgcctat
     5821 gaagagttgc ttggaaagaa gcagttttta ggacatacgc cagctaccca tctacttgcc
     5881 agtcaatccg ccccgctcac gctaggctac tttctggcaa gtcagatggc gggtaaatct
     5941 ctgagggagc aagctcccta cagactccct cccaaaaaaa gaaaggtgga agaaaaaaat
     6001 gaactatcca tattttaaag tctcggcttc agaagaaact aaagaaatat tcaacaattt
     6061 ttacaaccaa aacaaaggaa tttttggttc aaaggcaaat atgtttcgtg ttatggtttc
     6121 aaatttacca gtgttagcta gtccatcaaa taataaattt aatgatcctg aaagcattaa
     6181 atttgaacaa aaaatttcag aactagaatc aatgataagt aatgaagtaa ttgaaaagct
     6241 ggatgacatt gatcaaaagt tatcgtattc tctaaaaaac aaatacaaaa cggaggagaa
     6301 aaaagatgtt taaagtttac ttcccgtttc agtggctcgt taaaggaatt cttttagtgc
     6361 tactaggatt gattcttttt ggaagttatc taacaattaa agccagacat tttccagaag
     6421 aaaagccaat aaaaattgta acaaaagatt taaaaatagg tgaaacttat caggcagatg
     6481 gggttgaact aacatttaaa aatattgaag tgaccgaaaa aagaaatgaa tttgcacaac
     6541 atgatcgtgt attacaagtg acctatacac ttataaatga tacagaaaat ccgatacgtc
     6601 cacaacaatg gtcgattgaa aataaggatg gtgaagaact ttatgagtat gatatgatat
     6661 tggataatcc agagtatatt gaaagtggca aagaagaaac agtaaattac tattatgaat
     6721 taccgattga aaggcaggac taccaaatcg tagtacgtag agagaatggt tacatagttg
     6781 ggttgccatt tactttataa gttttatttt gttagtagtt tttaaggtaa tatcagtttt
     6841 gtgatttttg aaaatggaac tgggagaatg gctgaggaaa ataaagttgt tccgtttgaa
     6901 acattagtga taaataagga agagtttgag caactttttc ttgatttttt tattcaatat
     6961 gacatgattt atgattttag ttcgtcacta gatttatttg aattagaagc agaaataata
     7021 gaaaacagtc gagagaagaa tggtaaaatc attatttcag tagaaaaatt caatgaatta
     7081 ttctcacaaa catttgaaat agatccagac tattatcaac cacaagaagt ttttcgagag
     7141 tttagaaata agattattgg ttttagtcaa actacaaaat gaaagcttaa taaagcaagt
     7201 gttgatagaa ttattcctca acgcttgctt tattttatgg gcacttcata atagaggtat
     7261 agagaagaga ggtattcatt ttggatacta ttactccaac aaacttcaaa gaaaatatag
     7321 gtaaagtgtt gcaagaagta gttcattcaa attctgaaat agaaattact agggattcta
     7381 aaaatggatt gaacgatggc gtcattatga tttctaagag aaaatgggag ttgttacaag
     7441 aagaacttta tttacaacga acgggtacat gggcttatgt atctgattta
//
LOCUS       DAFLWQ010000114         7283 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.117, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000114 DAFLWQ010000000
VERSION     DAFLWQ010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7283
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.117"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(170..3319)
                     /locus_tag="L1V16_002670"
     CDS             complement(170..3319)
                     /locus_tag="L1V16_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBN1276953.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWSNLRQ
                     KIISNNQAELNDSPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIERENPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIIQIELK
                     QVTAKDGFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGVSSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMESVKKESYLDPTVFEAEEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKESDWLIKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTAWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVQSSTLNNQIQLLEE
                     QIGVYETVKGSLMEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDNLIHA
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(3333..4550)
                     /locus_tag="L1V16_002671"
     CDS             complement(3333..4550)
                     /locus_tag="L1V16_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBN1276954.1"
                     /translation="MSNDTRPEIRFPGFTEDWEERKLGDMMDVTSVKRIHQSDWTNSG
                     IRFLRARDIVSAAKNEEPSDYLYISEEKYNEYSKNSGKVSQGDLLVTGVGSIGVPLLI
                     TDDNPIYFKDGNIIWFKNEHKIDGNFFYYSFINNKIQKYIRDVAGIGTVGTYTIDSGK
                     KTPISLPTYDEQIKIGSFFKQLDHTIMLHQHELDLLKETKKGFLQKMFPKNGAKVPEV
                     RFPGFTGDWEERKLGEVVVFLNGRAFKQQELLDSGKYRVLRVGNFNTNDRWYYSNLEL
                     EEDKYANKGDLLYLWATSFGPEMWNEERVIYHYHIWKLKFLSKELDKQYLYTWLLTDK
                     EKIKESTNGTTMVHVTKGGIEQRTFQFPPDINEQQKIGAFFKQLDDTIALHQRKLDLL
                     KETKKGFLQKMFV"
     gene            complement(4540..6135)
                     /locus_tag="L1V16_002672"
     CDS             complement(4540..6135)
                     /locus_tag="L1V16_002672"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBN1276955.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYSISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHEQ"
     gene            6260..7045
                     /locus_tag="L1V16_002673"
     CDS             6260..7045
                     /locus_tag="L1V16_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SinI family restriction endonuclease"
                     /protein_id="HBN1276956.1"
                     /translation="MPNKNRTFESILNEGLTTEPASIIFDEVIDDVEDSKYHKNLKEL
                     FYFALNNGPSLFTGISVPDSDNPLIMAKIYLTKWCNKYIRDRNNPALKKPLKTFGEKD
                     AALTTRVAANANIDDQKVLNDYLRGHFLYMSAENMNGSILEEYLAEVLEPEGWIWCAG
                     SVYRAVDFCYLGTSPILLQVKNKYNTESSSSSAIRVGTTIRKWNRLNKSTKISGLDSP
                     IPNWKALIEMTEASKELAAKLTENSYLAYINEKSTRELWTLDD"
BASE COUNT         2132 a         1477 c         1199 g         2475 t
ORIGIN      
        1 tgcaacagaa ccggtaaatg aatgaaaaag atggaagaat cattattcaa tagctttctt
       61 aaatactccg ttataaaatg tgaacaagta aaaagacatc tatccctatt ttctacactt
      121 ccactttact actatctttg aatcgtacaa ttttcttaac tcttctcgtt tacctcaatt
      181 cattttcaag tggaatcaac tcatcatcta acattttacg ccatgctcgc ttcatttctt
      241 gtgggtattt aaatggtttc gcttctggat gtttggcttt atatccttcg taatccttac
      301 tgttgataat tgctttcata ttaggaattg gatcttcacc tggcatatat tgcagattag
      361 aagcatgtaa ttctttctca gaaacaaacc actcattgga aaaggcatga atcaaattat
      421 cacttgcttg tgtaaaatag cgacgtttaa tgacaaagat atcttcatta ctatctaaag
      481 tccccacatc aaatgcattt aaaatttgtc ggtaaacttc tttgactcct tctgttttat
      541 tcaatttagc caaagctttt tcaatttctt ctcgtgcatc tgaactattc gcagcataag
      601 ttcctagtaa ttgatcaata taagtagaat caatatcata caacttagtg gtattttcac
      661 tataaaattc gatcgttgaa aaatcttctc cctctttttc tggttcttcc tccatcaatg
      721 aacccttcac ggtctcgtac acgccaattt gttcttccaa aagttgaatt tgattgttca
      781 aagttgaaga ttgcaccatg tcatcattgt aatcatcata agtcactaac gattcatacg
      841 cacgattcaa ttcttgaaat gctttgacgt actcgatacg gatttcaagt ggcgtatgtt
      901 catcaatgga ttccatggat gaaacctctt ttaacttacc atatgcttgc ttgaatcttt
      961 ttttggattc ttggtaactt ggataaatca aacccgattc ttctttagct tctgaataca
     1021 gttttgtcgc atcctcgaca ttcttctcca ttgtcgctgg ctttcggaaa gtaacaatta
     1081 gtccttttgt tttttcagga tacgtacggt tcgtacgtga aaaggcttgg atcaatcctg
     1141 catactctag attacgatcc acaaataggg tttgaatcgt aggggcgtca aaacctgtca
     1201 atagacgatc cactacgatt actaaatcga tttgtttccc aaattgtttg aattccgctc
     1261 tttttcgtgc caaacgatta ttgatgtctc cgttataacg ctcaatgtct gctagtgacc
     1321 aggcagtatc ataatactga ttatattcct caataatttt ttgcatttct tcttgttggg
     1381 cacttgaatc tcggctattt tcttctaatg aataggtaat agcgattcgt gggaaatcag
     1441 gatcctccat cgttcgtcct tcacggatag gctgattggg aaactctttt attaaccaat
     1501 cagattcttt cgtcatctct ttgatggccc gataatactt tttggccata tcaatggaac
     1561 tcgtggttaa gatcgcagac ttcgttggac ggccatttcg aaaatcaaat tttgtatagg
     1621 cattgtctgg acggaacatt ttatgaatga ctttttggat atgttcctct gcttcaaaaa
     1681 cagtagggtc caaataactt tcttttttga cagactccat ttgatcgatc atacgattga
     1741 tctgttccgg tgaatactct gcatatgttt ctacttcttt taatttccga tagattttat
     1801 tctctaatga agtcggctcc acggtgtttt catgctctac ttgaaatcct aaaaccgagc
     1861 catcttctaa tgcattcttg atggtatagg tgtgcaagac ctctccatac tgatcatggg
     1921 tcgtacgtgc caattgccct ttggcttgtt tccgattctc agggaaaatc ggtgtacctg
     1981 taaagccaaa ccaagtggat ttcggaaaca tttttttgat ttcttccata ttttcagcac
     2041 ttaacgctcg atgacactca tcaactacaa acacgatatg ttgccccatt aatttttgga
     2101 agcgattggt tccttttttc tcttcctgtt tctttgcata tttcaacgcc gcatctagtt
     2161 tttgacgggt tgtaatgatc acaacattcg cattggcatc tgccaacaga gtttcactta
     2221 actctttggc acttcctgtt cccacgatca agctattcgc tttggcatta ccagaagaaa
     2281 ccccagtatt aaactccgaa gcaaatttcg taaactctgt ggtggtctga ttatctaaat
     2341 ctttgcggtc cactaacatg atcgttcgat cgatccccga ttttcgtgct aaaagcttag
     2401 tagatacaaa actagtcaac gtctttcctg aaccagtcgc atgccacaca taccctgatt
     2461 gatgtttatt tgcggcaata aacaaggctt gaatcgcatg cacttgataa ggatgtaaca
     2521 ccatgagggt tttattgtct tgatcttcac tgacaatcgt ataatccgca atcaagcgat
     2581 gggcatctgg gatatttagc acttgtttgc aaaactcata taagttttct acctttttat
     2641 tatctttcgt tcgccaacta aataaaaact taggatgcaa atccttcggt aaggcatttg
     2701 caaaataccg agtcgtttgt tcattggaaa ccacaaacaa ctgtaaggtc gaaaagatat
     2761 tgttccgaaa catgccttct tcagcatatt ttttgatttg attaaacgcc tgataaaaac
     2821 catcttttgc agttacttgt tttagctcga tttggataat cggtaagcca ttgatcaata
     2881 aggtgacgtc aaaacgtcga tcccgcgctt ctatgttact tccacgtttt gcaatttgat
     2941 ggaccacttc ataagtagag attcctccac caatgtcttg attggaataa aggataagtg
     3001 agacagaacc caattgcgga ttttcccgtt caatcgtgat ccgagccatc ccattttcac
     3061 cttttaacca tttcgcagca tcaaatgggg ttttcgtccg tagcaataat tcggttttga
     3121 tcgtttcaaa ctctttatcg gtcaaaggag aatcattcag ttctgcttga ttatttgaga
     3181 tgattttttg acgtaaattg ctccaaagat cttcttctga ttttagatcc ggacgatacg
     3241 tccactgatt atgtccttcc ccgaggacac gaatcaactg ttcttcgact tccgcttcct
     3301 cacggtgact aattttcatt cttcttccct ccctaaacaa acatcttttg caagaagcct
     3361 tttttcgttt ccttcagcaa atctaactta cgttgatgaa gagcgatcgt atcatctagc
     3421 tgcttgaaga aggcaccaat tttttgttgt tcatttatat ccggtggaaa ctgaaatgtc
     3481 ctttgttcta taccaccttt agtcacatgt accattgtcg ttccgttagt tgattcttta
     3541 attttctctt tatcagtcaa tagccaagta tatagatact gtttgtccaa ttccttagat
     3601 aaaaatttaa gtttccaaat atgataatgg tagattacac gttcttcatt ccacatttca
     3661 ggaccgaagc ttgttgccca taaatataag agatctcctt tattagcata cttgtcttcc
     3721 tctaattcta agtttgaata ataccatcta tcattagtat taaaattacc tactcttaaa
     3781 accctatatt ttccagaatc aagtaattct tgttgtttaa aagctctacc attcaaaaaa
     3841 actaccactt cccccaactt ccgctcttcc caatctcccg taaatcctgg aaaacgaact
     3901 tctggcactt ttgctccgtt tttagggaac attttttgta agaatccttt tttcgtttcc
     3961 ttcagcaaat ctaattcgtg ctggtgaagc atgatggtgt gatcaagttg tttgaaaaat
     4021 gaaccgatct tgatctgttc gtcataagtt ggaagtgaga taggtgtctt tttaccacta
     4081 tcaattgtat aggttccgac ggttccaatg cctgcaacgt cacggatata cttctgaatt
     4141 ttgttattta tgaacgagta gtaaaagaag tttccgtcaa ttttatgctc attcttgaac
     4201 caaatgatgt ttccatcctt aaagtaaatt gggttatcat cagtgattaa taaggggaca
     4261 cctattgatc cgacaccagt tacaagcaag tctccttgag aaactttacc tgaatttttc
     4321 gaatattcat tatatttttc ttctgaaatg taaagataat cggatggttc ctcatttttt
     4381 gcagctgaga caatatcacg agcacgtaaa aatctaatac ctgagttagt ccaatctgat
     4441 tgatgaattc gcttcacaga agtaacatcc atcatatctc ctaacttacg ctcttcccaa
     4501 tcttccgtaa aaccaggaaa ccggatttct ggtcgtgtat cattgctcat gtttgaacac
     4561 ctccagcgca ccttgtaacc acgcttcatt ttcaggtgtt gtttgcaggg aagagatagc
     4621 ttctaaaagt tctttttcta gcacttgctg ttcttgtcgt atcttcttga tgtcatttcc
     4681 gacatgaacc atatcaattg gttcttcttc ttcgaaagta tcgacatagc gtgggatatt
     4741 taagttatag tcattttctt tgatttcatc aaaggttgcc aaatgagcgt atttctcgac
     4801 atcttttctt tcagcgtagg tttcgaggat tttttgaatg ttttcttccg ataatttatt
     4861 ctgatttttc cctttaacaa attcacgact agcatcaatg aataatacat ctcgagtttg
     4921 acgattcttc ttcaatacaa tcaccgtcgt tggaatcgat gtaccaaaga acaagttcgc
     4981 aggcataccg atcacagcat aaatactgcc gtcttctaat aatttttgac gaatgacccc
     5041 ttctgcagca ccacggaata aaaccccgtg tggcaagacg atagccatag tccctgtttc
     5101 cttcaaatga tagaaaccat gaagaagaaa cgcaaaatct gctttggatt ttggcgctaa
     5161 tttcccgtag cgattaaacc gagaatcatc taagaaggtc gtatctgctg accaattagc
     5221 cgaataaggt ggattcatca ctactgcatc aaatgtgtaa ggttcatctg ttggccagtc
     5281 cttattcaac gtatccccat tgcggagatt catttcttcg gcatctaccc catgtaaaat
     5341 caagttcatt tttgctagat tgtatgtcgt tgtatttagt tcttgcccat gatatttaac
     5401 gttatctgga tgagttaagt agttacgtac atttaacatc aaggaacctg aacccatggt
     5461 tgggtcaaag acactaaaga atcgtcgttc tttttgatcc aacgtcacga tttgtgccat
     5521 catatcagaa accatatgag gcgtgtaaaa ttctccggct ttcttccctg cttctgaagc
     5581 aaattgactg atcagaaatt catacgcatc cccgatcaca tccccatcgt gacctaaaac
     5641 ttccacgtca ttcaatttct tgataacttc ggtaatcgtc acatttcgtt gttgctcatc
     5701 tgttcctagt ttttttgatt ggagatccac atcatcaaat aacccattaa attgattgta
     5761 ggtagatgcc aattgcacaa aggctttgtt tagatcgttc aattggaacg ttgcttgttt
     5821 tgcttgatcc gctaagacgt tgaaaagata ctctggtgag atcgaatacc ccaaaatatc
     5881 aacgattgtg gcaatcaggt cttcttttga ttcttcatct gaaagtaatt cacgatacaa
     5941 cattgtttgt ttgcttactg tgtcatattc ctctaaggat tcatctgcta aaagaaccac
     6001 ttgttccaac aaacggtcgg ataaatattt atagaaaatc agtcccaata aataattttt
     6061 atattctgac gcatccattt tactacggag attatctgcc gcactaaata atttttgatt
     6121 taattctgca cccaaaaaga tacactccta tctcttattt aaagttgcta tataccctct
     6181 tattttagca tactcccttt tagaaaaagc aaaaaaaaaa gaaaaaatct tattcttgat
     6241 aacaagctac gtgacgtata tgcctaacaa aaatagaact tttgaatcaa tcttaaatga
     6301 aggtttaacc acagaaccgg catccattat ttttgatgaa gttatcgatg acgttgaaga
     6361 tagtaagtat cataaaaatt taaaagaact tttttatttt gcactcaaca atggaccaag
     6421 tttgttcact ggtatatcag tacctgatag tgataatcca ttaattatgg caaaaattta
     6481 cttaacaaaa tggtgtaata aatacatcag ggataggaat aacccagcat taaaaaaacc
     6541 tcttaaaaca tttggcgaaa aagatgctgc tttaactact agagtagcag caaatgctaa
     6601 tattgatgat caaaaagtat tgaatgacta cttgcgtgga cattttttat atatgagcgc
     6661 tgagaacatg aacggaagta ttttagagga atatttagcc gaagtgttag aacctgaagg
     6721 ttggatttgg tgcgccggct ctgtatatcg agctgttgat ttctgttatt taggaacctc
     6781 accaattctt ttacaagtga aaaataaata caatacagaa agcagttcga gttcagctat
     6841 aagagtagga acaacaatta gaaaatggaa tcgtttaaat aagtcgacaa aaatttctgg
     6901 tttggatagc cctatcccca attggaaagc attaatagaa atgactgaag ctagtaagga
     6961 actggcagct aagttaactg aaaatagtta tttagcttat attaatgaaa aatccacacg
     7021 agaattatgg acactcgatg actaacaata tccttattag tatctatcca cgatacatgg
     7081 aaaaaattat aaacaaacaa aaaaactttg aatttagaaa tttctatctt acctcagatc
     7141 cttataatat cttttggatt tacgaaacaa tccccaccaa agctttaaag tataaattga
     7201 ttgtaaaaaa tccaattact aaacttaaga aaaatcaaca ctacttttta ggagacgatg
     7261 agtttgaaca attagtttaa aag
//
LOCUS       DAFLWQ010000115         7182 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.118, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000115 DAFLWQ010000000
VERSION     DAFLWQ010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7182
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.118"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..1398)
                     /locus_tag="L1V16_002674"
     CDS             complement(join(<1..825,825..1398))
                     /locus_tag="L1V16_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBN1276957.1"
                     /translation="MAKYTFELKLKIVHDYLDGKGGSDYLAKKYSIKAPSQVKRWINA
                     YQEFGEEGLVRKRQKKKYSVQFKLDAIELYLTSELSYREVANTLNMNNPNLIASWMRQ
                     FREGGIDGLSKTKGCPPILSKKNEPKNKKKSTTKATSKERERIEELEKRVRSLQIENA
                     FLKELRKLRKQEAQQRRMKQSHESSQASEDRFKLVELLETLKFPKATFMYWQKRLDRK
                     NPDQEIEAEMLKIREKHKDYGCLRMTNELRNRGFSINKKKVQRLIKKLGIKVTAYTRK
                     SRRYNSYRGQVGAVAKNRIHRRFYTSICHQKITTDTTEFKYHEADAKGIIRQKKLYLD
                     PFMDMFNSEILSYRISEKPNALAVMEGLEEAVQTTNDCPYRRMFHLDQGWAYQMKAYR
                     NKLKEYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYY
                     NNERIKQKLNWQSLVQ"
     gene            1641..2096
                     /gene="tnpA"
                     /locus_tag="L1V16_002675"
     CDS             1641..2096
                     /gene="tnpA"
                     /locus_tag="L1V16_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBN1276958.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            2361..2459
                     /locus_tag="L1V16_002676"
                     /pseudo
     CDS             2361..2459
                     /locus_tag="L1V16_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2682..2912)
                     /locus_tag="L1V16_002677"
     CDS             complement(2682..2912)
                     /locus_tag="L1V16_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HBN1276959.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(3142..3960)
                     /locus_tag="L1V16_002678"
     CDS             complement(3142..3960)
                     /locus_tag="L1V16_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1276960.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            4121..4810
                     /locus_tag="L1V16_002679"
     CDS             4121..4810
                     /locus_tag="L1V16_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBN1276961.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4824..6326
                     /locus_tag="L1V16_002680"
     CDS             4824..6326
                     /locus_tag="L1V16_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1276962.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            6339..6815
                     /locus_tag="L1V16_002681"
     CDS             6339..6815
                     /locus_tag="L1V16_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1276963.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6912..7022)
                     /locus_tag="L1V16_002682"
                     /pseudo
     CDS             complement(6912..7022)
                     /locus_tag="L1V16_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2326 a         1136 c         1299 g         2421 t
ORIGIN      
        1 attggacaag actttgccag tttaatttct gttttatccg ttcattattg tagtaataga
       61 tatagctatc aatggctgat tttaattcct cgaaacagtt ataaactttc ccgtgaaaaa
      121 tctcttgttt taataagcca aaaaaattct ccataagtga attatctaag cagttccctt
      181 tccgagacat gctttgaaag attttgtact ccttcaattt gtttctataa gctttcattt
      241 gatacgccca accttgatct aagtgaaaca tacgacgata gggacaatcg ttagtggtct
      301 ggacagcttc ctccaaacct tccattaccg ctaatgcatt gggcttttca gagatacgat
      361 aggataaaat ctcactattg aacatatcca taaaaggatc tagatacaat ttcttttgac
      421 ggataatgcc tttggcatcc gcttcatggt atttaaattc agttgtatcc gtcgtgattt
      481 tctgatggca gatactggtg tagaaacgac gatggatccg atttttggct actgctccaa
      541 cttgtcctcg ataagaattg tagcgacgtg atttacgtgt gtatgccgtt acttttattc
      601 ctagcttctt gatcaggcgc tgaactttct ttttattgat agagaaaccg cggtttctta
      661 gttcattggt catccgtaaa cagccataat ccttgtgctt ctcccgaatt ttaagcattt
      721 ccgcttcaat ctcttgatct ggatttttac ggtccaatcg tttttgccag tacataaagg
      781 ttgccttagg gaactttaaa gtttctagaa gctcaactaa tttaaacggt cctcggaggc
      841 ttgcgatgat tcgtgcgatt gcttcattcg tcgttgttgg gcttcctgtt ttcgcagctt
      901 cctcaattct tttaaaaagg cattttcaat ttgaagggaa cggactcgtt tctccaactc
      961 ctcgatgcgt tcgcgttctt tagacgttgc tttagttgta gattttttct tatttttggg
     1021 ttcatttttc ttagacaaga taggtggaca tcctttcgtt tttgagagtc catcgatccc
     1081 accctcacgg aattgacgca tccaactagc gatcaaatta gggttgttca tgttaagtgt
     1141 gttggcaact tcacgatagg acagctcact tgttagatat aactctatcg catccagctt
     1201 aaattgaaca gaatattttt tcttttgtcg ctttcttact agaccctctt caccaaattc
     1261 ttgataggca ttgatccagc gcttcacttg tgatggagcc ttaatggaat atttctttgc
     1321 cagataatca cttccgcctt taccatccaa gtaatcatga acgatcttta atttaagttc
     1381 aaaagtatac ttagccataa aaaataccga cctccaaaag ttagattttt tggtctaact
     1441 tttgggggtc ggtacaaaac ttaaaagttt tagacccttt tattttctta atgacttcag
     1501 tcagttttgt gcgtaaagcg tgcgaaacaa gaaaaccgcg cgtttctacg cgtggaagaa
     1561 gtatctttag cgataaaaac tcctttcgat atactagtga gtggctacca accgctcatc
     1621 agatcgaaag gagttttttc atgtcaaatg acgataaaag tttagcatat actcgttgga
     1681 attgtaagta tcatattatt tttacaccaa aatatcaacg aaaagtaatc tatgggcaat
     1741 tacgaaaaga tcttggaaaa atacttagga agttgtgcga aatgaaagat gtggaaatca
     1801 tagaagcaca tgcaatgcta gatcatattc acatgcttgt tcgagtacca ccaaaaatat
     1861 gtatatccag ttttatgggg tatctgaaag gtcgtagtgc ggtactaatc cacgagcagc
     1921 acgcaaatct caaatataaa tacggaaaca aatccttttg gtcgaagaga tactatgtga
     1981 gtacagtcgg attgaatcaa aagacaaatg aaaaatacat ccgtgaacaa gaagctgatg
     2041 atcgcattcg atatattata agtaaaagag agtacgtaga accatttaaa aaataaagag
     2101 aagtaagtga gtgaagatga gcagttggcg gtcttttaaa aatccccttt taaggggcag
     2161 cgagtgtcga ccccttctag ggggattaaa aatacacccg tcctcacggg tgtatgggtt
     2221 actgatagac ttgattttaa ctggtgtcag aaacttatgt ccagaaaggg tgatgaaatt
     2281 ttggcaattt acggctattc aagaattagc acaagcaacc aagattacaa aacacaaatt
     2341 caaacattag aaaatgctgg cgcagaaata atcttcctag aaaatcactg gattatcgaa
     2401 cacctttgga agtatttttg agttacgtaa gtattgatga tctgtctaac ttaatttgac
     2461 aattaagagt atatttactt cagatggtaa ggcaacaaaa taaaatacaa taggcagatg
     2521 aactaataaa taaaatctgt attaaataca gataaattaa tataaaaatc aaaaggatca
     2581 taaactttta acaagtgatg aaatgggtgg aaattgattc ttatagacag tttgtctcat
     2641 aacattgaag tattttgcaa ttttagcatt gaaacacttt tttaatcttc aacgttgttc
     2701 ttataaacaa gatgattggg aatcttttga attaacactg tatagcttag aacacccttt
     2761 atagaaaaca ttcgcttagc aatcttaata attccttgtg cccgatgtcg tttagattca
     2821 gtaggttcct gctcatcgat catggaaaaa atttgaagga tcagatcctt aataaattta
     2881 tttaagagag gatgatccat tgcttcatcc atactcgata aactagtgat aatgagctac
     2941 acgtttttct ttcaagttga tcaatagctt ccacgataaa aatatcttta gataaaatca
     3001 agaaccgtag gaactacagg gatatttggt caataagagc caccgctatt agtaaaaaat
     3061 aagctatcaa gtatgctctc atcccaagaa ttgcctactt caatcgttaa aaaccgttag
     3121 gtttagctaa gtgggggtag ttcactcaat acttttatca ataatagagc gcaaaacttt
     3181 ttctcttaat tcaactgaat caatattatt gttttgttca taaccatgaa ctaatagatc
     3241 acaaatataa agttgtgata tttttccagc taaagatcca ccattaagaa attcttcaat
     3301 ggctgtttgt aaaactaagt ctgcagactt tcctataggt gaatgaatat agttagttat
     3361 agcaataatt tttgcgccat tttttttagc tattttcaat gaatcataag tatctttcgt
     3421 tttcccagat aaagaaaaaa tgattactaa atcattaact gttaataaag aagcgacttg
     3481 ggcttgaaaa tgagggtcta gtacagcttt tgcttgaact cctacgcgaa gaaacatatt
     3541 ttctaaatca agactagtat ttccactaga tcccactcca aatatatata tgttttttga
     3601 ttgagtgatc attttaatgg cttcattcaa tttttcttcg tctaaaagcc taatagtgga
     3661 atagagagct tctgttaaac tattagcaat ttcatcatag tactttacac tagtcggatg
     3721 ttcttttttt tgactaaagt cttcctttgc aatttcaatt tttaaatcag aaaaaccaga
     3781 aaaaccaatt ttttgacaaa agcgaataat agtagcatcg ccaacttttg tgtttttctt
     3841 aatatcactc atcgtactat aaataatagt tttcccagaa tttaaaataa aatcagcgac
     3901 ttttttttca gacttcgtta aaaatggata attttcttta attaaataga tataactcat
     3961 acaaactcct ctacaatttc aacttttctc cattatactc caaaataata aaaaaaactc
     4021 ctaaatactc catttttatc tttactttta tgaaagcgga tgctatattg tttttggagt
     4081 tgttatccaa aaataataaa aaattggagt gtttaggata atggataaaa agaggttttt
     4141 agatcttatt tcaaaaggtt tgattgtttc ctgtcaagca ttacctggtg aaccatttta
     4201 caaagaggaa gaaagtttaa tgccttattt tgctttggct gctcaaaggg ctggagcagt
     4261 tggtatacgt gcaaattctg ttcgagatat tattgaaatt agaaagtgtg tatcattacc
     4321 aatgattgga attattaaaa gagattatcc accagaatct ccattcatta ctgccactat
     4381 gagagaagta gatgaattag tagaaaccgg tgttgaggta atcgctcttg attgcactct
     4441 tagaaatcga catgatggac tatctataaa ttcttttatt actaaaataa aagaaaaata
     4501 tcctcatcag ttatttatgg cagatatttc tacatttgaa gaaggcaaaa atgcatataa
     4561 agcaggaata gattttgtag gaactacttt aagtggatat actgaggaaa gtaaaaaaca
     4621 agatgggcca gatatagatt tgattaaaaa attggtagaa gaagggattt gtgtaattgc
     4681 tgagggaagg attcatactc cagaacaagc aaaagagata aaaaaaatag gagttgcagg
     4741 tattgttgtg ggtggtgcta ttactcgacc acaggaaatt gcatcaagat ttgttaaagc
     4801 attaagttag ggggagaaat aaaatgttta aaaaattttc acaattagga cgcgctttca
     4861 tgttaccaat tgctatatta ccagtagccg gattactatt gggactggga ggagcgttaa
     4921 caaatgagag tgctataaat gcttatccat ttttagatca accgtggttg catacaattt
     4981 taagtattat gagttatgct ggaaatgcag tttttgcaaa cctagcacta atttttgcaa
     5041 ttggtattgc tgtaggactt gcaaatggag ataaaggaac agctggttta gctggtggag
     5101 tagcttatct agtatatact gcaactatta gtgggtttct tgaacttttt tcagcaaaag
     5161 atgcaacact agatacaggt gtagtgggat caattgttgt tggtggtact gttgcatttt
     5221 tacacaatcg ttatagaaaa attgaattac cacaattctt aggttttttt ggaggatcaa
     5281 gatttattcc gattgtttct agtttagctg caatcattat tggttctttc ttttatttaa
     5341 tttggccacc aattcaaaat ggtttagtag ttgctggtga acaaattgcc caaatgggta
     5401 gtttaggaac ttttttatat ggttttttat tgcgtttaac aggtgctgtt ggactacacc
     5461 acaccattta ccctttgttc tggtatacat ctttaggtgg taccgaaact gtagctggat
     5521 caacaattgc tggagcccaa aatattttct ttgcccaact agctgatcca aaccacactg
     5581 gtctgtttac ttatggtact agattttttg caggaagatt tgcaacaatg atgtttggat
     5641 taccagcagc atgttatgca atgtatcgtg caattcctaa gaaaaatcgt aaaaagaatg
     5701 gtgggcttta ttttagcggg gcccttacat catttttaac tggaattact gaaccagttg
     5761 aatatatgtt tttatttgtt gctccttggc tttatgtgat tcatgcattc ttagatggat
     5821 tatcttttta ttttgctgat atcttaaata ttcgtgtagg gaattccttt tcaggtggtt
     5881 tgatcgactt tttattattc ggtgtacttc aagggaatga caaaactaat tggttaaaat
     5941 taattccttt tggtattgca tgggcattta tatatttctt tgtttttaca ttctttatca
     6001 aaaaatttaa ggtagctatt cctggaatgg aagaagaatc agaagttcat tctgaaaaag
     6061 taataaacaa aaatacatca ttacatgaag agtctcttat cattattgaa gctcttggtg
     6121 gaaaagaaaa tattgagtct gttgaagctt gtgcaactcg tttgcgtgtt gctgttacga
     6181 atggggagat tattcaaaaa caaacaataa aagacactgg tgcaactgct gtcttcgaag
     6241 tgaagggtgg catccaagct gtttttggag ggaaagctga cttattaagt caagaaatca
     6301 atcaaatatt aggaaaagat aattaggagg tttttaatat gtttgaaatt ttcaaaaaga
     6361 aaaaacaaga aactttttat gcaccttgtt ccggaaaaat catttccatc acagaagtaa
     6421 atgatcctgt cttttcacaa aaattactag gtgatggttt tgccgtcata cctgatggtt
     6481 caaaaattta tgctccattg gctggtcgag taacaaatat atttcctact aaacatgcta
     6541 ttaatataaa aagcaactca ggcattgatt atttgattca tattggaatt gatacagttg
     6601 aattacaagg agagcctttt tcgatttgtg ttcaagaaaa tgatgaggtt actcctgaaa
     6661 cctcgttggt tgatgtggat tttgacaaaa taataaaatc tggtaaagat acttctgtta
     6721 tagttgtttt tccggagaaa aatcagttca atgatttaat aatagataat ggtcgaattg
     6781 ctcatgggaa ttcatgtgga aaaatcactt tttaaaaaag tgtatataaa aagctataaa
     6841 ataagctaaa taggatattt gtcaaatgaa gttggtgaac agaaagaact gttttctttc
     6901 tgttcatttt tttattttat tagtaatgat tccccatgcc aaatcatgat ccgtaattta
     6961 aagttataaa agcttcgaaa tccattggca tttcgttgga ataccttgat atgattattc
     7021 aaatataaaa tatagagaga agagagagag ggaagatatt tataaagggc aaagttatgt
     7081 ttactcaact taggaaatag aaatagatca atttatattc tcttgtcaat cgaatatgaa
     7141 ccttagcact atataccaaa tatagtaaaa tgctgaaaga tg
//
LOCUS       DAFLWQ010000116         6895 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.119, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000116 DAFLWQ010000000
VERSION     DAFLWQ010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6895
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.119"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..182)
                     /locus_tag="L1V16_002683"
     CDS             complement(<1..182)
                     /locus_tag="L1V16_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBN1276964.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
     gene            517..951
                     /locus_tag="L1V16_002684"
     CDS             517..951
                     /locus_tag="L1V16_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBN1276965.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            974..1294
                     /locus_tag="L1V16_002685"
     CDS             974..1294
                     /locus_tag="L1V16_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276966.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            1435..1626
                     /locus_tag="L1V16_002686"
     CDS             1435..1626
                     /locus_tag="L1V16_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276967.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(1697..1954)
                     /locus_tag="L1V16_002687"
     CDS             complement(1697..1954)
                     /locus_tag="L1V16_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBN1276968.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            2112..2375
                     /locus_tag="L1V16_002688"
     CDS             2112..2375
                     /locus_tag="L1V16_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276969.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            2399..2587
                     /locus_tag="L1V16_002689"
     CDS             2399..2587
                     /locus_tag="L1V16_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276970.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(2670..2855)
                     /locus_tag="L1V16_002690"
     CDS             complement(2670..2855)
                     /locus_tag="L1V16_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276971.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            3070..3441
                     /locus_tag="L1V16_002691"
     CDS             3070..3441
                     /locus_tag="L1V16_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBN1276972.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(3591..3663)
                     /locus_tag="L1V16_002692"
     tRNA            complement(3591..3663)
                     /locus_tag="L1V16_002692"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3628..3630),aa:Gln,seq:ctg)
     gene            complement(3709..4137)
                     /locus_tag="L1V16_002693"
     CDS             complement(3709..4137)
                     /locus_tag="L1V16_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276973.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(4197..4955)
                     /locus_tag="L1V16_002694"
     CDS             complement(4197..4955)
                     /locus_tag="L1V16_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBN1276974.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            5250..5447
                     /locus_tag="L1V16_002695"
     CDS             5250..5447
                     /locus_tag="L1V16_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276975.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            5553..6035
                     /locus_tag="L1V16_002696"
     CDS             5553..6035
                     /locus_tag="L1V16_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276976.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(6093..6689)
                     /locus_tag="L1V16_002697"
     CDS             complement(6093..6689)
                     /locus_tag="L1V16_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBN1276977.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
BASE COUNT         2332 a         1059 c         1355 g         2149 t
ORIGIN      
        1 gaatttgatt ctgcaatggc attgatcaag gagttatcac caacgtattt ttgagaaatc
       61 gttgatagag tatcacctga ttgaacggta taagcttcgt ccgcatgagc agtcgttccc
      121 atgaagaatg cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt aagtgatgtc
      181 atgaaaaatc tcctttattc gttaaaaagt tttatttgtt gtgttcaacg aggaatactt
      241 taacacgtga aaatatttca taggtaaaag aagcatgaca atttatgaca aatccacgtt
      301 ttttgtaaca gaatgatgtt cgctcgatgt gaaaaatgat gaggaatttc acataatgca
      361 gaaataatgg gattagaaca ggtgttctga tgagaaaaga aatgtataaa taacttgaaa
      421 gaaattgctt ttgttcatca ttttatttac atattgcgta tattttttgt atttttgctt
      481 gagatgttac aataaaagaa aaaggaggcg gttccaatga gtaaaagata ccagaacatc
      541 atggtagcag ttgacggatc aagacaatcg atcaaagcgt tcgctgaagc ccttgactta
      601 gcaaaggaca atgaagccca cttatttatc gtgtcaatca tcaacaaagt tgagctgacc
      661 catagtgcct atgccttttc aaaaatctat gcagatgaaa aacaaagaac agaagtagcc
      721 atgctgaaaa aaatcaatga tgccaaagag tacggcattg ctgagatcca cgcaatagtt
      781 gaaactggag atccaagaaa tttgattgcc aatgtcatcc ctggacaaga aaatattgat
      841 ttgatcgtta tgggagcgac aggaaaaggt gctatacaac aagcattagt tggatcgacc
      901 gcttcttatg tcgtatcaca tgccccttgc agtgtgttgg tcgtgaagta atgagataag
      961 ggaggaatag aaaatggttc gtcctcaaga agtccgtgcg ccaaaagaaa aaatagaaat
     1021 tttagcaatt attgaagacg gcacacaaac aaagaaggga tactcgatcg ctttagtaaa
     1081 gtggaaagga aaaaaaggtg ttgctctgag atgggatgga gataaccaac aagataaagg
     1141 attccctgtc acagctaacg gttatcatcc agcgtggttt gttctgcctg ataaatttat
     1201 ggaattatac agctatgatt atgcaagagc cgcagcatca atcaaagcat tagataaatt
     1261 aacagaagag cagaatgaaa tggaggaaaa ataaaaaaga cgaaccaatc agcctttaga
     1321 aaactgatta gttcgaggag taaaaatgaa aaaaggttat ttgggatgaa actagaataa
     1381 tgcgtataac ttaaataaaa cttaaagcaa taaaatggca agagggtgag gcaaatggaa
     1441 gcaggaaaag tattacagga agtaaaagca ctatgtgcag ataaaaaata tgaagaagcg
     1501 aaaagcctga tcgaaaagaa caaagaaaat ttggaagaaa agtacccgat cgcacaagaa
     1561 tttatagaat taaaacaagg aacgatcctt caccgattca aacatttttt tggtataaca
     1621 gaatagaaaa aacgattaaa gatcggcaga aatttgctgc atctttaatc gttttctttt
     1681 taaacatgcg agggattcaa ttctgattct tatataaaaa atagatccaa ataataagaa
     1741 aaattactga aagcgtcaat tcgatgatgt gtgttattaa tacagacgtt gtttcccaat
     1801 gcctaaaaga aaaaatttga taagtaaaat atacagcagg taaagaggcc agtaaaactg
     1861 aaaacttctt ttttgtccat tttatgtaat agaaaagaat gcttatcata ataaaaaaag
     1921 gaatataaaa aacaaattga ccgatcgcga tcatactatt gcctccgata aataaagtcc
     1981 atgatacaaa ataacacttt gtgcgaaatg gcgcaagcag ttttgtggat ttatccggta
     2041 aaatctgtat cgattttgaa attagaggag aaacttgcta taatcaaagt gaaagaagga
     2101 gtgggatttt catggatcat gtagtgttag aaatcgattt gcatttgatc aataatattc
     2161 gggtgattta ctatgttgta agtaacagtg tcgaacaacg tgtactgacg aataaaataa
     2221 atggtatttt agcaaagaaa gacgttcacc gattcaataa tggtgaagga agttattata
     2281 gtatcccagt agaaaaaatt atttatacga cagtcaaagt cagagaagat ctagatacca
     2341 aaaaagcata tgaacctatt tttacaactt attgattgac agcagatgga ggaaaaaaat
     2401 gaatccatat gaacaactta ttcaagattt gatcgatgga aaaatcgaaa agattgatgt
     2461 aaaaagagaa gaattaatgg cttttcgaga agcgtggctg aagttggaga atcgtaaata
     2521 tgtggtggga aaagcctcac tgaacggcaa tgtgacttat cattacgatc cgacacgttt
     2581 attttagtat gaagtattca gaaaagaacc aaaggaggac gatgcagcag cattgtcctc
     2641 ctttgatttt acaaaagtga aagttttact tatttgaata gatttttaaa tttgtttttg
     2701 acactgtcga tatttacatc ttttaaaaga ttttgggctt tctctttata aggtcctaat
     2761 tgttctttat gttcttcgat aaatcgtttt gcgccatcga aattgccgtt cttaatcatt
     2821 tccttgactt tttgaaataa ttcttcttga ttcattttga acacatcctt tgctatcaac
     2881 atgatttttt acatggacaa aacgagaaaa actgatttat ccacacgtca ataatatcaa
     2941 ataacgatca tttttactaa aaaaacactc gattctcgct tctaaagtag gagaaaaatc
     3001 tccaacttgg gacggatgga atttctttaa ctgacccata tactgaatat ataacaagga
     3061 ggtagaaaga tgaaagtgat taaatatttg attggactgg cggcgattag tggtattttg
     3121 ctatttggac tgaaatatta tactgaagga agttatggag aaatccctgg tatacttgat
     3181 cagctaaatc cattagttga aaaaggagag gtctatgtaa agacacaaaa accagaggaa
     3241 gtaaatgaat atggtacagc aaggtatgtg cagaaagctg ctgatgccaa tgggaaagaa
     3301 cgaacggttg aatttaatgg tctttctgtg ttaaaagaaa atcattattt gaaaattagc
     3361 aataaaggag cacacataga aacgtatgag gaagttccta gagaaaaagt tccggagaaa
     3421 gcattagcaa ttattgggta aatcagtttt tgtattaaga atacgcccga ttttattatt
     3481 cataatttaa ttatgtaaac taaatacaag tagtaaaaat aatacaataa tccccctgca
     3541 aaaagattgt tcttttacag ggggttcatt ttttcagcaa gcacatcaaa ttgggatggc
     3601 agggttcgaa cctacaattg cttgattcag agtcaagtgc cttaccagtt tggctacatc
     3661 ccatttattc aacaaaataa tcatagcact ttcctaaaaa aacgcaagtt atttttcttg
     3721 atcggatagt tgttgcttta ctcgtaaaag gcggcgtact agtttctttt ctaatccagc
     3781 aggaagggca atcagttctg ctactgacaa gacggtgtcc aataactgat attctttgac
     3841 aggttcattc ataatatgat agatgtttgc taaacgttca atatattcaa agcgagtata
     3901 ctctgttcga gcaattagaa atttcaataa atcggtggct ttctcgtact cttgatctgc
     3961 gtaataaaca agagattgac gatacaattt gatttccagt tcattgaggg tagcaggtct
     4021 gcgacgctcg ttccactcat taatagagac tttaccttga acatttccct tgcagtcacg
     4081 gacaaaaata atcggaattt catttggatc cattttttta tgtgtgaatt tttccattat
     4141 ctacgctccc ttcaaaggtt tggtatcttg agtataaggg atttttgttt gaattactag
     4201 cttttctcca aagttagcat ctgtccaccc attgcagtga aaatcgccga aaaatcgttg
     4261 atcggtactg ctcgattttt tacaccatag ggatcgttga cataaatatt ttctttgtca
     4321 tatccagtga ctacacaagc atgaacaaga ggagtgactc ttacttctcc attatttgtg
     4381 gtccaagtca taaaatcagt ttcatctggg acttcaaaat tgatagtcac agaagtccag
     4441 acaggatttc ctttagatag tgcttttttg atatcatcga gttgagcatc ggtttttgga
     4501 aaagtgtgat aatccgtttg gacgatttgc tgagcaaggg aggcaactgg gggaacatag
     4561 acgaccatag cccagtctcc gccactgata tcaccaacaa atccttcatt aggatcgcca
     4621 tgagtcccat ctgcattgaa aacagggacg taatccaatt gctcagctaa ctggttttta
     4681 gttgtttcat aaccataaaa agataaaagc atagaaagcg aagtgacttc acagccattt
     4741 tctaaagaag gagaatcaaa ctggctctct aatggaacat ctagtaaaac ttctgctttc
     4801 tcttttgtct ttttcgtttt ttgtgttgaa cttttttgtg cagtgttcat tgtatgttct
     4861 ggagaatgga tatgtaggta ataacttgta ccgcttaata aaagagcagc tgtgccccct
     4921 agaaacaata gttttttgaa cgtttttttc ttcatttgaa atctcccttt tcagctgttt
     4981 atctttccta ttataaatgt atttttattg gaaatggaag tattatattt taatatgtag
     5041 gaaataatta gtttttaagg aatatgtttt aattttttga aaaaaattct tctaaataca
     5101 acagctgttt taattgtgaa aacgaaaaca gtacgctata atgcctgtaa ggttgatttt
     5161 taactgtaaa taaaaatcaa tgagttaaat ctccaaagaa atagcagtgg taatgtggag
     5221 aaaagttcca gcagtttagg aggattttga tgacggaaga aatgattaat ttaggagaac
     5281 aatatgcatg caaaccaatt ggttttacaa aaacggtcat tggtgaagtt gtatcaaaaa
     5341 tgacaaactg cgccgtggtc aaagttgccc aatgtgctgc agaggaccaa gaattattag
     5401 atgaaaaagc aagcatggtt gttgcaaaat atgatacatt tgaataaaga aaacaattgg
     5461 acgtgcggcg tgctgcaagt ccaatttctt tgagaaggta aatcagtatt cttttcctat
     5521 tttctggaga agaaaaagcg aggcgagttg tcatggtaac attctttacg gttctattgt
     5581 ttttattcgt tgttgtgatg tttttatttc tttggctggt tcgaaaagaa attatttatc
     5641 ggactgtgcg aaatcgatgg gtctacttgg tgataccctt cttagtgtca ctagtcattt
     5701 ggtatacact catcagtcat cctacagcag atgaattggc aaaagggatc ttgtcagcaa
     5761 tgatttttat tagttttttg ttggacagta gaggaatcac agaagaagga cttgttttga
     5821 atagctttga caaaaaaggt gttccttttt ctgagatcaa taaaattgta ttatatcagc
     5881 caaaaggttc taaaatcgta aaaatgaatt ttttccgaaa cggatggcga ggaccgatgc
     5941 tgaaattttc tgcatcatta gaagaattag ttccattttt gtcccaacgc ttaaacgatg
     6001 aggcagagat tgatattatg attgatccag aataaaaaca gaggttgcga caagatgttt
     6061 gtcacaacct ctgtttttta tttcaaataa aattatccaa atacgcggaa gcgatcggca
     6121 tcgttcatgt attctttttc ctcagccggt gtttctggtg aaccgaatac taattgcgaa
     6181 cgtagtttcc agtttgaagg gatattccat tcttttgcaa ctgcttcgtc aataactggg
     6241 ttgtaatgtt gcaagtttgc gcccaatcct ttatcaacta atgctaccca agtattagct
     6301 gttgcgattc cgtttgattg ttctgaccaa tctgggaagt tgtctgcata taattcaaat
     6361 tgttcttgta gaccttttac cacgtcagta tctttgaaga ataatactgt accataacca
     6421 tttttgaaac cagctaattt gttttgtgta tttgggaaag cttctgctgg agtcaatggg
     6481 cgaagtgctt cttcagtgat ttcccaaagt ttttcatgtg catctccgaa aaggataact
     6541 gcgcgtgttg attgagcatt gaaagcagtt gggctttctt taattgcttc tttgatcaaa
     6601 gttgttaatt cttcattaga aagtgaaaca ttacgtccta gatgatagat tgaacggcgg
     6661 tttttcaaag tgtcagtaaa agttgtcata ataaaatttc tcctttgatt tgcgttttgc
     6721 atttttttaa ttgattacga aatgaagtat agcaccttac aaaaagtaag taaacagata
     6781 tgctcacaaa aaataagcga agttcaaaaa acaattttaa taagaaaaat cgttatgtaa
     6841 ggattttctt agttatcgct ttcattgttg tgttttagga atttttgctt atttg
//
LOCUS       DAFLWQ010000117         6729 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.120, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000117 DAFLWQ010000000
VERSION     DAFLWQ010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.120"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(47..871)
                     /gene="iolB"
                     /locus_tag="L1V16_002698"
     CDS             complement(47..871)
                     /gene="iolB"
                     /locus_tag="L1V16_002698"
                     /EC_number="5.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
                     /protein_id="HBN1276978.1"
                     /translation="MEKTLKHQPLNKELAPGVKQIQNIRQSNSALSYIEFQILELEKG
                     ASYKETGSQQEVCIVILTGKIKVKAADTWYEDLGTRESVFEKIPTDSIYLPAEHSFEL
                     VATTDNVRLALCYSPAKKALPISVIRAEDNTVEERGLYQNKRLVHNILPDNVDTASSL
                     LVVEVYTEGGNFSSYPPHKHDQENLPHESFLEETYYHELDPEQGFVFQRVYTEDRSLD
                     ETMTVEHQNVVEVPKGYHPVGVPDGYTSYYLNVMAGPERIWKFHNEKKHEWILQRK"
     gene            complement(910..2826)
                     /gene="iolD"
                     /locus_tag="L1V16_002699"
     CDS             complement(910..2826)
                     /gene="iolD"
                     /locus_tag="L1V16_002699"
                     /EC_number="3.7.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione
                     acylhydrolase (decyclizing)"
                     /protein_id="HBN1276979.1"
                     /translation="MEKTVCLTTAQALLKFLNQQYISIDGKETPYVEGIFHVYGHGNV
                     LGIGQALELEPGHLKSYSGKNEQGMAHAATAFARQNLRKKIFAVSTSVGPGAANLLTA
                     AGTAFANNIPVLFLPADTFATRQPDPVLQQLEHASSVAFSTNDAFQAVSRYWDRINRP
                     EQLMSALLRAFEVMTNPATMGPATICLPQDVEAEAYAYPEEFFKKRVHYIDRRIPTAR
                     ELAEASQRIKASKRPVIIVGGGCKYSEAGEILEQISRDCQIPLVETHAGKSTVSWDFK
                     NNLGGMGILGTSAANKAVQQADLIIGIGTRYTDFTSASKSIFNFEQAKMMNINVSRQQ
                     AAKLEAFQVVGDAKATLEQLAPMIEGYQTAYGEKIDELKEEWISERNRLKAAHFKRKD
                     FTPEIKDHFSQEILNEYADALATNLTQTEVFIHLNDFVDEDAIVIGSAGSLPGDMQRL
                     WNPVKENTYHLEYGYSCMGYEIAGAMGVRMARPEQEVYALVGDGSFLMLHSELVSSLQ
                     YDKKINIVLFDNSGFGCINNLQMDNGGASQGTEFRNTKDEIMNIDYAKVAEGYGAKTY
                     RVSSIAELQAAVEDAKKQTRSTLIEIKVLPKTMTEGYDGSWWNVGISEVSGKAAMQEA
                     YKAKQAKLATIRKY"
     gene            complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="L1V16_002700"
     CDS             complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="L1V16_002700"
                     /EC_number="2.7.1.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-2-deoxygluconokinase"
                     /protein_id="HBN1276980.1"
                     /translation="MSYIKFDQSKEFDLLLLGRVAIDFNPAYNDQVKEEFKPLKKVHM
                     FEKFVGGSPANIAVGVTKHGMKAGFIGTVSDDQFGEYVIDYFNEQGIDTSQISKAQHG
                     EKLGLTFTEMLSSKESNILMYRNQAADLQLSVEDIDEDYLKRSKALLISGTALAESPS
                     REAVIKAVMLAKRNNVKIIFDIDYRAYNWKNNDDISIYYSMIAKESDIIMGSREEFDL
                     TEKLIQPNMSDNESAAFWHSCGAEIVVIKHGMKGSTAYTADQQQFSIKPFPVEARKGF
                     GGGDGYGSGFLYGLFEGWEIIDCLEFGSAEASMMVKSNNCSDSLPTTQEVKDFITLEK
                     EIYGEMIARI"
     gene            complement(4028..5044)
                     /locus_tag="L1V16_002701"
     CDS             complement(4028..5044)
                     /locus_tag="L1V16_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016633586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1276981.1"
                     /translation="MAGTIKEIAEKAGVSRGTVDRALNDRGRINPEVAERIRAIAKEM
                     NYVPKKKKVIKETTLKLGIVTQLAKSSFMIPIRSGLESIIGDLKKRNIDCFLEEVDGV
                     DEAAQLQALDRLVELGVKGIAIMPVDSDGIREKINQLTDQGILIITFNSDILGTNRQC
                     FVGMDNFKSGKTAAGLLGMLTKGKGKVLAITGYFGNSVNSLRVAGFVEELKESFPELE
                     LTGVQSSFDSSAEVEKILSNTLENYSNLDGVVVFSGGQAGIARALEKIDESKRPFVII
                     YDLTKNNIEMLKNDQVDFLIDQDGFVQGYRSLLMLANQLQNNKTVTKDALFTDIIIKT
                     KYNI"
     gene            complement(5146..5343)
                     /locus_tag="L1V16_002702"
     CDS             complement(5146..5343)
                     /locus_tag="L1V16_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276982.1"
                     /translation="MKFICLSCGEKESIPMDVVKFLDDADIANDPNNPPQFTCEKCGK
                     EMYPEYYRNALGIEFKISDVQ"
     gene            complement(5315..6634)
                     /locus_tag="L1V16_002703"
     CDS             complement(5315..6634)
                     /locus_tag="L1V16_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016372324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="HBN1276983.1"
                     /translation="MKANILEAIFFDEHHNWDNFVEKYGRKIRLVVKREVNKFRYCGD
                     IQKGYRLFVCEGCHQTKFVPLKCRGKFCPTCATGESQRWSAVVANDMFKVTHRHVIFT
                     IDEGLREIFMMENYRDSLLKGLMDEAAKIILAYFEKRKVKAGIVATIHTFGSKLEFNP
                     HVHMVVTMGGLTRDGSWEEYDYLPFSMLRKYWKNAVLKLIRRTLGEWDKQRVQSRLQA
                     AYKNNGEGFYVNAPKRSRTNLKSLLQYISRYMKRGPIALSRILMYDGDTVMFNYMDKR
                     TNTKETMTMSIDEFIAALIRHIQNKNFKTIRRYGIYSRRIKTLMKKVMKEYQKRVKKL
                     FINLNEALRPKSWEERITEEFGENPLECSCCGEYYEFVGMSVRKNGRLVIKYAKDNHA
                     KRFMREENRKIDQKEFRQQYEEEKEKTFKAIRWDWERQREIYMSKLW"
BASE COUNT         1772 a         1639 c         1159 g         2159 t
ORIGIN      
        1 acctaactaa acctaactaa actttatgta tctaacagct taataactac ttgcgctgca
       61 agatccattc gtgtttcttt tcattgtgga atttccaaat tcgctcaggt cccgccatca
      121 catttaaata gtaggaagta tacccgtcag gtaccccaac tggatgatag cccttaggaa
      181 cttcgacgac attttgatgc tctaccgtca tcgtttcatc tagtgaacga tcttccgtgt
      241 agacccgctg gaaaacaaat ccctgctctg gatcaagctc atggtaataa gtttcctcta
      301 aaaaagactc atgtggcaga ttctcttgat cgtgcttatg aggaggatag ctggaaaaat
      361 taccgccctc ggtataaact tcgacgacca gcaggctgct ggcagtatcg acattatccg
      421 gtaaaatgtt gtgaacaagt cgtttattct gatagagtcc acgttcttcg acggtattat
      481 cctccgcgcg aatcacactt atcggcaaag cttttttcgc tggtgaatag caaagcgcca
      541 atcggacatt gtctgtagtt gccacaagtt caaacgaatg ctccgccgga agataaatac
      601 tgtcggttgg aattttttca aaaacagatt ctcgtgttcc taaatcttca taccaagtgt
      661 ctgctgcttt aaccttaatt tttccagtca aaatgacgat acagacctcc tgttgactgc
      721 cggtttcctt gtaagaagct cccttttcca gctccaaaat ctgaaattcg atataactca
      781 aagcagaatt agactgccga atattttgga tttgttttac tccaggtgcc agttctttgt
      841 ttaatggttg atgcttcaat gtcttttcca atcaatccac tccttatttt caatcacaaa
      901 aagcaatatt taatactttc tgatagtggc aagtttcgct tgtttggctt tgtaagcctc
      961 ctgcatggct gctttacccg atacctctga gataccgacg ttccaccagc tgccgtcgta
     1021 gccttctgtc atggttttag gaagtacctt tatctcaatc aacgtcgatc gcgtttgctt
     1081 cttcgcatcc tcgaccgctg cttgtaattc tgcaatcgag cttacacgat acgtttttgc
     1141 accatagcct tcagcaactt tggcgtaatc gatgttcatg atctcgtcct tggtatttct
     1201 gaattcggtt ccttggctag ctccgccatt atccatctgt aaattattga tacagccgaa
     1261 accagaatta tcgaaaagta caatgttgat ttttttatca tattgcaaac tagaaaccag
     1321 ctcgctatgc aacatcaaga aactgccatc gcctactaag gcatagacct cttgttctgg
     1381 tcgagccatt cttacgccca tcgcaccagc gatttcatag cccatacaag aataaccgta
     1441 ttccaaatga taggtattct ccttcacagg gttccataag cgctgcatat cccccggcaa
     1501 tgaaccggct gaaccgatca cgatcgcatc ctcatcaaca aaatcattta aatgaatgaa
     1561 gacctctgtt tgcgtcaaat tcgtagccaa cgcatcagca tattcattca agatttcttg
     1621 agaaaaatga tctttgattt ctggcgtaaa atctttacgc ttaaaatgcg cggcttttaa
     1681 ccgatttcgc tcactgatcc attcttcctt cagttcatcg atcttctcgc cataggcggt
     1741 ttggtaacct tcgatcattg gggcaagctg ctccaaggtc gctttcgcat caccaaccac
     1801 ttgaaaggct tccagcttag cggcctgttg tctgcttacg ttaatattca tcattttcgc
     1861 ttgttcaaaa ttaaaaatac ttttagaagc tgaggtaaaa tcagtgtagc gtgtgccgat
     1921 ccctatgatc agatccgctt gctgcacagc tttattagca gccgaagttc ccaaaatccc
     1981 cattccgccg agattgtttt taaaatccca cgaaacagtc gatttacctg cgtgcgtttc
     2041 aactagcgga atctgacaat ctcttgagat ttgctcaaga atctcaccag cctccgaata
     2101 tttgcagccg cctcctacga tgatgacagg tcgtttactg gcctttattc gttgactcgc
     2161 ttcagcaagc tcacgagcgg tcggaatcct gcgatcaata taatgtactc tttttttgaa
     2221 aaattcctcc ggataggcat aggcttctgc ctccacgtcc tgcggcaaac aaatcgttgc
     2281 cggacccatc gttgccgggt tcgtcatgac ttcaaaggcc cgcaataacg cggacatcaa
     2341 ctgctctggt cgattgatgc ggtcccagta gcgagaaacc gcttgaaatg catcatttgt
     2401 cgaaaaggct acactgcttg catgttccag ctgctgcaag accggatcag gctgacgtgt
     2461 agcaaacgta tccgccggta aaaaaagtac ggggatatta tttgcgaatg ccgtacccgc
     2521 tgctgttaac agattggccg cgcccggtcc aacagatgtt gatacggcaa aaattttctt
     2581 gcgtaaattc tgtctggcaa aggcagtagc cgcatgggcc attccctgct cattttttcc
     2641 gctataactt ttcaaatgtc cgggctctaa ttccagcgcc tgaccgatcc ccaaaacatt
     2701 tccgtgacca tagacatgaa agataccttc aacataaggc gtttctttgc cgtcgatgct
     2761 gatgtattgt tgattcaaaa attttagtaa tgcttgtgct gttgttaaac aaaccgtctt
     2821 ttccattttt ttcaccttaa atccgagcga tcatttcgcc gtatatttct ttctccaatg
     2881 taataaaatc ttttacctcc tgagtcgtcg gtaaagaatc tgaacagtta ttgcttttga
     2941 ccatcattga tgcttccgct gagccaaact ctaaacaatc gatgatctcc cagccttcga
     3001 ataaaccgta taagaaaccc gagccgtaac catctccgcc gccaaagcct ttgcgtgctt
     3061 ccaccggaaa cggcttgatt gaaaactgct gctgatcggc cgtataagca gtcgatcctt
     3121 tcattccatg tttgattacg acaatctcag caccacaact gtgccaaaaa gcagcgcttt
     3181 cattatctga catgttaggc tggatcaact tctcagttag atcgaactct tctcttgaac
     3241 ccatgataat gtctgattcc ttagcaatca tcgaatagta aattgaaata tcatcgttgt
     3301 tcttccagtt ataagcacgg taatcaatat caaaaataat tttgacatta ttccttttcg
     3361 ccagcatcac tgccttgatt acggcttctc tggacgggct ctctgctagt gcagttcctg
     3421 agattaatag tgcttttgac cgtttcaagt agtcctcatc aatatcctca acgctaagct
     3481 gcaggtctgc ggcttgattt cgatacatca aaatattact ttcctttgat gagagcattt
     3541 cggtaaaagt cagccccagc ttttcaccat gctgcgcttt gctgatctga gacgtatcga
     3601 tgccttgttc attgaaataa tcgatcacat attcgccaaa ctgatcgtcc gagactgttc
     3661 cgataaaacc agctttcatg ccatgtttag taacacccac agcaatattg gcaggagatc
     3721 cgcccacaaa tttttcaaac atatggacct ttttcaatgg tttaaactct tctttgactt
     3781 gatcattgta ggcaggatta aaatcaatag cgactcttcc taaaagcagc aagtcaaatt
     3841 cttttgattg gtcaaacttt atataactca atatatccac ctctttatcc gttcttctat
     3901 ttctgaggca agtatagcac gccaaaacaa agcgtgcaat atttatttta gaacgcaata
     3961 ttgcgtgctg tttgaaaatg acggcaaaaa aaacgtgaat cgccttacat cacgattcac
     4021 gcctagatta aatattgtat tttgtcttaa taattatatc agtaaatagc gcatcttttg
     4081 taaccgtttt attattttgc agctgattcg ctaacatcag taatgaacga tagccttgaa
     4141 caaatccatc ttgatcgatt agaaaatcaa cctgatcgtt tttcagcatc tcgatattgt
     4201 tcttagtcaa atcataaatg attacaaagg gccgcttgct ttcatcgatt ttttccaacg
     4261 ctcgggcaat tcccgcttgt ccgccagaaa agacgactac gccatctaag tttgaataat
     4321 tctccaaggt gttgcttaaa atcttttcaa cctcagcact cgaatcaaag ctgctctgaa
     4381 cacccgtcag ctccagttca ggaaacgact ctttcaattc ttcaacaaag cctgccaccc
     4441 gtaagctgtt gacgctattt ccaaagtagc cggtaatcgc tagaaccttg ccctttcctt
     4501 ttgtcagcat acctaacaat cccgcagccg tttttccgct tttgaagttg tccatcccaa
     4561 caaaacactg tcgattcgta ccaagaatat ccgaattaaa ggtaatgatg aggatgcctt
     4621 gatcggtcaa ttgattaatt ttttctctga taccatcact atctactggc atgatcgcga
     4681 tcccttttac tccaagctcc accaatcgat ccaacgcctg cagctgggcc gcttcatcga
     4741 ccccgtctac ctcttctaaa aaacaatcaa tgtttcgctt ttttaaatcc ccgataatag
     4801 attccagacc tgatcggatc ggaatcataa aagaagattt cgccaattga gtgacaatcc
     4861 ccagcttgag cgttgtctct tttatgacct tctttttctt tggaacatag ttcatttcct
     4921 tggcgattgc tctgattctt tctgcaacct caggattgat ccttcctcga tcgttcaatg
     4981 cccgatccac tgtccccctt gacactcctg ctttctcagc tatttcttta attgtacccg
     5041 ccatcttgcc tctccttttt tcctattgtg tttattttat cacaaaactt aagaaaacca
     5101 ccggagaatg aattctccgg tggacttttt gtatgattaa ccttcttatt gaacatcact
     5161 gatcttaaac tctattccaa gggcgtttct ataatattct ggatacatct ccttcccaca
     5221 tttttcacag gtaaattggg gaggattgtt cggatcattt gcaatatctg catcatctaa
     5281 aaattttact acatccattg ggattgattc tttttcacca caacttagac atataaattt
     5341 cacgttggcg ttcccaatcc cagcgaattg ctttaaaagt tttttctttt tcttcttcat
     5401 actgttgcct gaattctttt tggtcaattt ttcgattctc ctctcgcata aaccgctttg
     5461 catggttatc tttcgcatat ttaataacta accgtccatt tttgcgcaca ctcatcccaa
     5521 cgaattcata gtactcaccg caacaagaac actctaaggg attttcacca aattcttcgg
     5581 ttattctttc ttcccaggat tttggtctta aggcctcatt cagattgata aacagctttt
     5641 ttactcgttt ctgatactcc ttcatgacct ttttcattaa tgttttgatt ctacgactat
     5701 agattccata gcgacgaatc gttttgaaat tcttattttg aatatggcga atcagtgcag
     5761 ctatgaattc gtctatactc atggtcatcg tctctttagt attcgttcgt ttgtccatgt
     5821 agttgaacat gacagtgtcg ccatcataca ttaagattcg gcttaatgcg atcgggccac
     5881 gcttcatata acgactgatg tattggagta gtgactttag atttgtcctg ctccttttag
     5941 gagcatttac gtaaaaccct tctccattgt tcttgtacgc agcttgtaat cttgattgaa
     6001 ctctttgctt gtcccactca cctaacgttc gtctaattag tttcaataca gcatttttcc
     6061 agtattttct taacatagaa aaaggtaaat aatcgtattc ttcccaactt ccatctcttg
     6121 ttaagccacc catagtaaca accatatgaa catgcggatt aaattctagt tttgatccaa
     6181 aggtgtggat tgtagctact atacctgcct tcacctttct tttctcaaaa taggcaagaa
     6241 taatttttgc ggcttcatcc attagtcctt tcagtaagga atctcgatag ttttccatca
     6301 taaagatttc ccgtaacccc tcatcgatcg taaagattac gtgccgatgt gtcactttaa
     6361 acatatcatt cgccacaacc gctgaccacc tttggctttc acctgttgca cacgttggac
     6421 agaactttcc acgacatttc aagggaacaa actttgtttg atgacatccc tcgcagacaa
     6481 acagtcggta tcctttttga atatctccac aatatctaaa cttgtttact tcccgtttga
     6541 cgactagccg aatctttcgc ccgtatttct caacaaagtt atcccaatta tggtgttcgt
     6601 caaaaaagat tgcttcgaga atattcgctt tcatagtaat attttacttg ttcaaaaaca
     6661 aaatgaaaag ggctaaaaga ctggtagtgc agccttttta gcccttaact ttttatactt
     6721 tctttactg
//
LOCUS       DAFLWQ010000118         6720 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.121, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000118 DAFLWQ010000000
VERSION     DAFLWQ010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.121"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            168..1040
                     /locus_tag="L1V16_002704"
     CDS             168..1040
                     /locus_tag="L1V16_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1276984.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            1037..2995
                     /locus_tag="L1V16_002705"
     CDS             1037..2995
                     /locus_tag="L1V16_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1276985.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(3246..4097)
                     /locus_tag="L1V16_002706"
     CDS             complement(3246..4097)
                     /locus_tag="L1V16_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1276986.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            4220..4687
                     /locus_tag="L1V16_002707"
     CDS             4220..4687
                     /locus_tag="L1V16_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBN1276987.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(4950..5432)
                     /locus_tag="L1V16_002708"
     CDS             complement(4950..5432)
                     /locus_tag="L1V16_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBN1276988.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(5532..6395)
                     /locus_tag="L1V16_002709"
     CDS             complement(5532..6395)
                     /locus_tag="L1V16_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBN1276989.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         1995 a         1392 c         1233 g         2100 t
ORIGIN      
        1 attgattacg ttaacaataa ttcgtttcat gtgactagat catactaggc atgaaaaatc
       61 tctgaggaac atggtttccc taggaggttt ttcgtgtcta tttttgtttg gccgcaatca
      121 actggtctag caaacgtgaa aaccaaatct tcaaaaaggg tgcgcgcatg aaaatcaaaa
      181 agatctttaa tcaaaatgca gtattggtag atgacggtgg acaggaaaaa gtagctattg
      241 gaaaagggat tggatttgac agaaaaagaa atgatttgat ttttgatcgt gatgtcgaac
      301 ggatatttgt catggaacca gaaggtcaaa tcaagttgca aaatttactt aatcagattg
      361 atgaacgctt tttatttgca gcagaaacga tcattgatca tgcggaaact gttttgatgg
      421 aaaagttgaa tgaacatgta ttgatcgctt tgaccgacca cattgctttt tctgcggaga
      481 acattaataa cggtatcgtc atccgcaaca aacttttaag agaaatcgaa gtgctttaca
      541 gtgatgaatt cagtattgct caatgggcag tagagtatct gacaaaagag cttgggattc
      601 catatactta tgacgaagca ggatatatcg caatccatat tcacagcgga cgaagcggtc
      661 ggaacaataa ccatcgcagt atccgtgaag tgacgattgt atctgacatc atccatttag
      721 tggaatcaga attggaaaca gatatccatt cagaaccatt ttcactgaat tattcaagac
      781 tggtgaatca tttacgactg cttctacaac gaacccatgc gcaacaatat gctgttttag
      841 acacggaaat cgtagaaatg gtcaaacgaa aatacccaga aagctataag atttctaaaa
      901 aaatccgtgt gttgctgacc aaagaatacc agctcgcgat cacgaaagaa gaactgggtt
      961 acttggccat ccatatcgag cgtttaagaa gcgcaatcgt acaaacaaat gttaacaatc
     1021 atgaggagga aaaaaattga aagcatatct acaacgaatg ggacgttccc ttcaacttcc
     1081 agttgcggtc ttacctgctg ctgctttact agtagggatc ggaaactggt gggcatctta
     1141 tagtaacgac attgtcgctc attttttaca agctggcggt aacgcagttt taggtcaatt
     1201 acctttgctg tttgccgttg ggttagcact agggatgtca gtggacaaat caggtgctgc
     1261 tgccttggca ggtttggtcg catttgaagt tccagtaaat gttttaaaaa ctgattcagt
     1321 agctacttta ttgaatatca aaccagaatc agttgatcca tcttttgctc agatcagtaa
     1381 cgtatttatt ggtattattg ccggattgat tgcggcagct ctttataatc gtttccacga
     1441 agcaaaatta ccgatggctt tatctttctt tagcggcaag cgtctagtgc caatcttggc
     1501 tgcctttgtc atgttgctga tcagtgcagt gctactgctc gtatggcctc cggtttactc
     1561 tgctttagtt tcttttgcta aattcatttt gagtttaggc tggggtggtg caggtcttta
     1621 tggcttcttc aaccgtttac tgatccctac aggattgcat caagcaatga actccgtgtt
     1681 ctggtttgac gtagcaggaa tcaatgatat tggtaaattt ttggcttctg aaggaacaaa
     1741 aggcgtaaca ggaatgtatc aagctggatt tttcccaatc atgatgttcg ggcttccagc
     1801 aggagcatat gctatttaca gaaatgcacg tccagaaaac aaagcaaaaa cagcttcctt
     1861 gatgctagca gcagcttttg cttcattctt tactggtgtg acagaaccac ttgaattttc
     1921 atttatgttc gttgcttggc cattatatgt cttgcatgca attttcactg ggatttcttt
     1981 agcagtgagt gcattcttcc attggacagc aggatttgcc tttagtgccg gatttgtcga
     2041 ttacttccta tctttgaaaa atccgattgc gaatcagcca ttgatgttga tcgtccaagg
     2101 attagtaaca gcagtgattt actactttgg ctttaacttt gctatcaaaa aattccatct
     2161 gatgactcct ggccgcgagg aagcagatct ttcagatgac gatactgcaa cgactaattc
     2221 agacaataaa tatgcggcac aagcaagcaa aatctacgct gcattaggcg gagccgacaa
     2281 tgtaacttcg atcgataact gtactacacg ccttcgtttg caagtcaaag atacaggcct
     2341 gatcgatcaa aataaaatca aagccactgg cgtacctggt atgaagatca tcgacggaaa
     2401 aaatgcgcaa gtcatcgtag gtacagaagt acaattcgtt gcagatgaga tggcaaaact
     2461 acatggtggt gctgcagcac gacctgcaca aacaaacacc gtggttaaaa cagaaacatt
     2521 tgccggtgaa acgatcgaac aagatattta cgctatcgca aatgggaaac tgattccaat
     2581 cactgaagtt tcagatgatg tattcgcgga aaaaatgatg ggtgacggct atgctgtatt
     2641 accagaaaat ggagaaatct tctctccaat cgctggtacg atcacaaaca ttttcccaac
     2701 gaaacatgct gtcggaatcc aaacagatgc tggtatcgaa gtcttgcttc atatgggcat
     2761 caacactgtt gacttaaaag gcgaaccatt cactttatat gtagaagaag gtcaaaaagt
     2821 cgcaagaggt caattgattg ctttagttga tcttgccgct attcaatctg caggcaaaaa
     2881 cacggatatg gtcgttgtat tcacaaatgg cgacaaagtc caaagcttag aaatcgaacc
     2941 cgcacgtgat gtaaaagcaa atgataaaat cggctctgtt tccaacaaag cctgagccat
     3001 cgtcttcccc agactttttt atcgataaac aaacaggagc tgagacaaaa atcttgtctc
     3061 agctcctttt tccgaataaa aacggcgttc tcctgccaac tccgcggtaa taagtccagc
     3121 taaacgaaac atatgaagag ctatttttta tttgactctt cttattactt gatgcagaac
     3181 agctttttca caaaattttt cttcatactc aaaactaatc ggctttttca caacctcttt
     3241 atacattatt cctgatccaa tatttctttt aatgctgctt caagagaagt taatggtttt
     3301 cccaatactt tttctaaatc atcagaggaa atagctaact gatccttttt aatatcatgt
     3361 tggatcgcta aaaacatgtc agctgcttct tgagggaatc cggcttcttt tagattttcg
     3421 acaaacgctg catcacttgc ttcaataatt tctaactctt tacctgtcgc acgctctaat
     3481 gccttggcta attcttcata gtcagttaga ttgccggata attctaagat ttctggagag
     3541 tcactttcta ctagtacttt tgctgcagct tctgcatatt cacgtttcaa tgcccaacct
     3601 gtttttccat ttcctgcagc ataaacgaat tgaccagttt ttaaagcctg cccaatgata
     3661 ggtaattcat tctctacata ccaattattc cgtaaaaatg tatgggaaat acctgaatcc
     3721 ttaatcattt tttcagtgaa ttggtgatct ggcgctaata cactgatcga gtgatcggca
     3781 tctgcaaaac ttgtataagc gatataagat accccagctg cttgtgctgc cttcactaca
     3841 ttcttatgtt cggcttgacg atttcctgga acgccagaga caaaaagcaa tcgatctatt
     3901 cctttcaacg cttctttcat tgagtctaaa tcatcataat caccaatacg tatattaaat
     3961 ccagcttctt tcagtgcttc tcctttttct tcactacgta ctagtacata gatttcattt
     4021 tgtggaacca tcttttttaa gaattccagc gcataaccac caaaacctcc agttgctcct
     4081 gttactaaat aatgcatatt tgccactccc tattcttttt atttgttaag atttacagct
     4141 gtacatttat aaattacacc tttatcataa agagtgtggt aagataagtc aagcaaaaaa
     4201 aatgaaagga tgacaactga tgaagtattc tctgcaattt agtgatgcaa tccatgtact
     4261 tgcctatatt gaaatgtttc aagatacccg atcactttct agtgagatga ttgccagtag
     4321 tatcgaaaca aatgcagcaa atgtacgtaa aatcatgagt cagctcaaaa aatccggttt
     4381 gatctttaca aaaaccggaa aaccgcagcc ttcccttgcc aaaagtccag atcagatttc
     4441 tttactagat gtctatcgca gcatcgaagg taatacacag cttatccaag tcgatccaaa
     4501 aacaaatcca aattgcgtcg ttggtgcgaa tatccaagaa gctttagaag aaagctacgc
     4561 tcggctgcag aaaaaggcag aagaagaaat ggctaagatc acacttgata gtctgataca
     4621 taaaatagcc gttttggaaa aagaaaaaag accagaaaac acaggcctcg tagagagatt
     4681 tttataattc tctctactgt gcctgcattt ttctgatcgg aatcgtctac ataaattctt
     4741 ttattctccg ggggacaaaa gccttgtcat gccccttttt cctctctaat gctcaggtca
     4801 aagcgctgaa gtcatgacgt cttgataaac ggtgttcaag tagctgaccc tcggcattag
     4861 ttctgaaaaa tgcaaaatat ggaaagctat ttcccatttt tcctctctaa tgctcaggtc
     4921 aaagcgctac tttcacgacc tctatattat catggtttat tgactaccgg tatccagatt
     4981 tctcccatat atttcccgtt ggtaactccc atttcgacta cagcatttgg acccccaaca
     5041 taggcgtaat cttctacttc tcttaaaaca tgcccaaagg ccgtattcgt caaatcattt
     5101 cttaattctt caggcgattc tgctaaagcg cttacaacaa gatacgttcc ttttgggaat
     5161 gggatgattc gcgtagtgtt tggaacatcc tgactcgttt gaacaccgac atagtacatc
     5221 attttcccgt tatagggttc gttgactgta aagaaataat gattttcagc agcttgtttc
     5281 aatgcatcta ttgttccatt accgataact ttttgctcaa atgcttgttt ctctgcagcc
     5341 aaaccgacaa aatccgtatt gctactcttc aattccacac caatacccgt caccgtaaaa
     5401 tctggttttt cttcgatcct atactttgcc atttctccca ccctttctat tatattaagt
     5461 tcatcttaca taaaattaaa gggaaatgac acgattacgc tcttttttct agggatattt
     5521 ttatttttta actatttttt tgctttcact gcaatccaaa tctcactgta aacattactg
     5581 aaatcctctc cccattttgt aaaagagatc tcgggagctt cgactaaccc ataatctgaa
     5641 gaaggaagcc attctgcata gattttcccc caagtatctt gtaaagtttg gggaaatggc
     5701 cctttattag gaaaaatggc ccaagtgtgt tcttctatag caagcatttc taaatcagcg
     5761 tacggatttt cttttgtcgt agcaaagcca atcatgtgca tcaaactgcc cttttcttcc
     5821 aagcggtctc catcaaatcc ataagaaacg ttgattactt gatttggata taaatctcct
     5881 aacttatgca tctcttccct ttgagtctcc gtgatcgtct gcgctaactt ttgtatttct
     5941 tgattgactc cttcaaattt gacaggaact tttttcgcca cacctgccac ataaaactgt
     6001 tctttctttt cgatacgaaa ttccatcgat tttcctcctc tgacatcaat aaaaaatgtc
     6061 aagcgtggaa aagatttttg tatgccgtat ctgctgattt ctgaaggcag atatcctgac
     6121 caatcacgaa aagctcttga aaaaccttcg actgtttcat atccatatct aaacgccgtt
     6181 tctgtcactc ttgatccatc tagaagatcg cgattagcca aagccaatct acggtttttg
     6241 atatagtcca ttagcgacat ccctgcaata aacgtaaaga tgcgttttaa ttgatattca
     6301 gagattcctg tattttcggc tattatttta taggaaagtc cttctgtcaa atgttcttcg
     6361 atgtaatcga tcaattggtt cagatcttta agcatattta tcttcctcct tgattgcctt
     6421 tttatcatat tatcaaagaa agtcaattac ttgatgaatc aggaaccaat ttagtcagat
     6481 gtagaaaatg ttgtatggat ctaaagaaaa ttctcaagca gcgtttcgta acggataatt
     6541 ggtattatct gcctatctat gttttacctt tagaaaaata aattttgggg aagacagatt
     6601 ctaagtaaac aaagcggtaa aaatatcttt tattccctta gttaatccgc ttactaccta
     6661 ctgtacaaag caaattgttg ttcaaactgc tgatcagaac gctgcttgga tttttctttg
//
LOCUS       DAFLWQ010000119         6702 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.122, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000119 DAFLWQ010000000
VERSION     DAFLWQ010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6702
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.122"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            105..962
                     /locus_tag="L1V16_002710"
     CDS             105..962
                     /locus_tag="L1V16_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBN1276990.1"
                     /translation="MEEKLIKKDEIIMGLLVPRANTYTIPLTKRQLIAKRYQRITRAI
                     NREFWNSESDTAHSLYVGSYGRGTAISTSDIDIIVELPMAEFDRFKNYLSNGPSKLLQ
                     VIKNAFQEILPNSDIRADGQVVKINFHDGIKFEIVPAFNEKDYLGESKGFIYPDSNMG
                     GNWKATNPKKEQEAMKLKNTKSNNLLYATCKHFRHVRDTEFTSYHLSGIVIDSFVYEA
                     MGNWKFVENNSGGQNISSVSYETALLEYYNSHKVMGGLNLYSPGSNQFVNSDSSIICL
                     EKVLKKIAL"
     gene            982..1542
                     /locus_tag="L1V16_002711"
     CDS             982..1542
                     /locus_tag="L1V16_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HBN1276991.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGVLSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADK
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNKTHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
     gene            2450..3217
                     /locus_tag="L1V16_002712"
     CDS             2450..3217
                     /locus_tag="L1V16_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HBN1276992.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
     gene            3243..3788
                     /locus_tag="L1V16_002713"
     CDS             3243..3788
                     /locus_tag="L1V16_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276993.1"
                     /translation="MGERTQALITVKYGNSKTKVSVSIHYQWGYGRFMLMDVLNQGIY
                     LINKAYDLRDESREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFEGQQIGLNKFCESGKEFATKDF
                     IKGYRLLLENYGINLEEESVK"
     gene            3789..4355
                     /locus_tag="L1V16_002714"
     CDS             3789..4355
                     /locus_tag="L1V16_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276994.1"
                     /translation="MFEKRKDQFPNLEAKSQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTIEGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMETENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGTDDCVAYYTTAE"
     gene            4370..4618
                     /locus_tag="L1V16_002715"
     CDS             4370..4618
                     /locus_tag="L1V16_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276995.1"
                     /translation="MEGMDFIDHEDLIDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDNTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            4637..4876
                     /locus_tag="L1V16_002716"
     CDS             4637..4876
                     /locus_tag="L1V16_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276996.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEELLRKAKQKGYPDKMLKQIGYYM
                     PEERIEKESCKVLFDSEQLLVLLTQNKLICQFENN"
     gene            4893..5477
                     /locus_tag="L1V16_002717"
     CDS             4893..5477
                     /locus_tag="L1V16_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1276997.1"
                     /translation="MNENKMVLSEYARLRTINWLNGMQSSGAFDGFDEENMDFESLSN
                     EDIRYYFIEWYFTEPDEEVEDEPELILERQRILFSEQDSKRLYGLYDLQLKGLKAQYV
                     ADSYDDMVEQGADRVVTYSEDDEEEWENYSDDEICFNDGYMPIEITEEEYDKVSDSDE
                     IGMCTVVSGLDIDVQRVEVAYQKMKERIKSKVES"
     gene            5584..5865
                     /locus_tag="L1V16_002718"
     CDS             5584..5865
                     /locus_tag="L1V16_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBN1276998.1"
                     /translation="MKVKNPKEKSRIQVGIDKDLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTMDMPVDVLDTDEKLEEWFNEA"
     gene            5855..6196
                     /locus_tag="L1V16_002719"
     CDS             5855..6196
                     /locus_tag="L1V16_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBN1276999.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     NKSDQIKRVYFPIAEWEKVGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSAIDTKKL
                     NRFIERLQRKV"
BASE COUNT         2525 a          871 c         1371 g         1935 t
ORIGIN      
        1 actttcaatt attgtgaaat atttcccttt aattaatcaa attttttata aaagtaatat
       61 ataaaataaa ttgcttgaag tattatattt agatatcata atttatggaa gaaaaattaa
      121 ttaaaaagga tgagattata atggggttac tggttccgag agctaatact tatactatac
      181 ctttaacgaa acgccaatta attgctaaaa gatatcaaag gattactaga gccatcaata
      241 gagagttttg gaattctgaa agtgatactg ctcacagttt atacgtaggt tcttatggga
      301 gaggaacggc aattagtact agtgatatag atataatagt tgaattaccg atggcagaat
      361 ttgacagatt caaaaattat ttatcaaatg gaccgtctaa gttattacaa gttataaaaa
      421 acgcatttca ggaaatacta ccaaatagtg atattagagc tgatggacaa gttgttaaaa
      481 taaatttcca tgatggaatc aaatttgaaa tagttccagc ttttaatgaa aaagattatt
      541 tgggtgagtc aaaagggttt atttatccag attcaaacat gggagggaac tggaaagcta
      601 caaatcccaa aaaagagcaa gaagccatga aattaaagaa tacaaaaagt aataatttat
      661 tatatgctac gtgtaaacat tttcgacatg tacgagatac agaatttacg agttatcatc
      721 tttcaggaat agtaattgac agtttcgtat atgaggctat gggaaattgg aaattcgttg
      781 aaaataacag tgggggtcaa aacattagtt ctgtatctta tgagacagct ttattagaat
      841 actataactc acataaagtt atgggcggtt taaatttata ctctcctgga agcaatcaat
      901 ttgttaattc tgatagtagt atcatatgtt tagaaaaagt attaaaaaaa atagctttat
      961 aaagttttat ggaggaacaa catgggagac gaaaaaaagc gcttggaagt tcaattacgt
     1021 gaagcatatg gacgagtaac gtatacttac accactcatt taaagcaagc cgataatatt
     1081 atttctgaca ataaaatttt aaggtgtctt caaattggtt tgtcagccct tactactgga
     1141 ggggtactta gtaccattat tactgataat agtgagttaa cctttgttgc tggattatgt
     1201 tcaacaattt ctcttggatt aaacttatac tttaagaatt ttgatcttgc tgaagaagct
     1261 aaaaatcatc aaattgttgc cgataaatta tggttgatca gagaagaata cgtaagctta
     1321 ctaacagatt taaatcgttt aagtgttgaa gatattgtga aaaaaagaga tcaattaatg
     1381 aacaaaactc atgaagcata taaaaatgcc cctaaaacaa atagtaaaag ctatgaatca
     1441 gctcagaaag cattaaaatc tgaagaagag caatttttta cagaagagga attggataag
     1501 atgttaccag agcatcttag aaaaaagagt tctaaatatt gaactctttt tttatgctta
     1561 aaattttctt gtaatttttc tattcaatca ataaataatc tatatttaag aagaaatatg
     1621 atgatagaaa catctcctaa agccaccgca agccgtccta gccattgccc agtccgacat
     1681 cgctagatta gtgcatctct ccaaaaaagt tttctaaagc caccgcaagc cgtcctagcc
     1741 attgcctagt ccgacatcgc tagattagtg catctctcca taaaagtttt ctaaagccac
     1801 cgcaagccgt tctaagcata gcttagcccg acattgctag atatgctcat ctcaccatga
     1861 acgtttccta aagccaccgc aaaccgtcct agccatcgcc tagtgcctag tccgattttg
     1921 cttgatcggt tccatttctg tttatttagt gggtcaacac cgtaatctta aatagccatc
     1981 gcctatttaa gattactagg tctgctttga aggtaaaaag tctttcattc ttcaagactt
     2041 ttaggctttc aagctacgcc tgaaagcatt gaaattcatc gctctttatt tggttttgcc
     2101 atttataatt ccttacgccc attatctttt tcgcctgtca taccttgtca gaagtgttta
     2161 gagcttatct catctttgga ttaatacaag tggcgtaaat ttttttctaa acgcaagcgt
     2221 tacgaaaata atttacttaa acacttgtat taatccggca gataagaacg cattctaatc
     2281 actcccgaca aggcaagaca ggcgaaaaag ataaataaat gaacgaaagg aagaaacata
     2341 aaatgcaaaa ccaaatagcg atgaagaaaa aaccacctcc ctctaaaaca atccaaacaa
     2401 aaaagaattt tgaaaaacca aaaatcaaaa acagaaagaa gcgttcaaca tgagagatag
     2461 aattttagaa gttaatcaag aaatggtaaa caagttaaca aatatcagtg ggaactatga
     2521 aaagtacgat ggtactttac ttgataatta tatttttcac gatacacaaa atatcagaat
     2581 tggcagaagt aaaccgagag cgttcattct catcaaagag aaatatttga atgaatggaa
     2641 tagcacctat gaaatggtta tgactgataa ctttgaaaag gtattggatt tcagaaatgc
     2701 tttgttgggt tctgatatgg gaaatagcag tcttgaatct attgaagttg aaaacaagac
     2761 cgagaatgaa ggtgaaggat tgattaagaa tgtcctgaaa atcgaacaaa aatatatcag
     2821 tgaagataga agtttttata gagtcacaag ctcggttggt ctagcaaact ttgctactaa
     2881 cttaattgga aacaatgcta gtgaatcttt gctagtgatg tgtctgaata caaagaatga
     2941 ggtcattgct tatagcgaag ttttcaaagg tggaattaat caatcagtag cgataccaag
     3001 agagattttt caactagctt tgctaaacaa ttcagcaaaa atcgcagtat cacataatca
     3061 tccgagcgga tatgaatttc caagtgaaaa tgacaaaagt tttactacga atttgaaaaa
     3121 cgcaggaaaa acaattggta ttgaattgtt agaccatatc atcgtaacaa gtaaaaacac
     3181 aagctattac tcatttcaag aaaatggttc tttataaaaa ttagagaaaa gaggaaaaca
     3241 agatgggcga aagaacacaa gcgttaatta cagtcaaata tggtaacagc aaaacgaaag
     3301 taagcgtgtc aattcattat cagtggggat atggtcgatt catgttgatg gacgttttga
     3361 atcaaggaat atatttaatc aataaagcat atgacttacg agatgaatca agagaagaat
     3421 tagcaaaagg aatctttgat agaagtacag gagttatcaa ttttgtcacc tatgaatctg
     3481 gagtgagtgc ttatgatgaa acagggtttg gtgggcgcta tgaaccttat caagaaacga
     3541 ttgaagatgt gatgaagttt tcagataaca atgatggcta tgctcattta gagatggtgt
     3601 tcgatgaaaa tggatttagt ctagatgata aaaccagatt gcgattgttt gattttgagg
     3661 gtcaacagat aggactaaac aagttttgtg aaagcggaaa agagtttgct acgaaagatt
     3721 ttattaaggg atacagatta ttgctagaaa attatggaat aaacctagaa gaagagagcg
     3781 tgaaataagt gtttgaaaaa agaaaagacc agttccctaa tttagaagcg aaaagtcaaa
     3841 aagtgattga tggtgaaatg attgaattat tccaaaaaag ttatggaacc atagaaacta
     3901 ccgcaagttg caaatactac tttcaaggaa agagaaacac gtttaaaggc tttgccgatt
     3961 ctgatgaaga attggcaaag aaaatcattg attggcttgt cagcagtgaa cacgtagcaa
     4021 gagaagatac cgttagaaca acgattgagg gtgaagtcct aacaggtact agatgtgttt
     4081 gttgtaatca tgaatttgta gaagatgaag gttgctaccg aatcaatgaa tatggtgatt
     4141 ttatttgcca gagttgccac gagatagaat ttccaaccga aagaagttgg tttgaataca
     4201 tgctacaaga ttatgagatg gaaacagaaa atggtgaagt agttttttgt accaaagagg
     4261 aattgagtaa gagaagcgat gatgaaattg aagattggtg tgtgtggtta gtagggacag
     4321 atgattgcgt tgcatattac acaacagcag aataggagtg tgaatcagca tggaaggaat
     4381 ggattttata gatcatgaag atttgattga ttttggttat acatggaaag gaatggtagg
     4441 tattagcaga agtcttgcta atgcctttta cgaaagaaat tatgcagtct atgtccttta
     4501 tgatgacaat acagaaagcc ttgttgatga agagtataaa ttggatttag agaatgtttt
     4561 atatgggata gaaaaagaag atttagcaaa atatattttt tcatggttgg gtcaataaac
     4621 gaaagagggt agcaacatga caaaattcaa aagtaaaggt atgcaatggt gttcttatta
     4681 ttatgttggg aatgatgaag agcttttgag aaaagccaaa caaaaaggtt atccagataa
     4741 gatgttaaaa cagattggct attacatgcc agaagagaga atagaaaaag aatcttgtaa
     4801 ggttcttttt gatagtgaac agctattagt tttgttaact caaaataaat tgatttgtca
     4861 atttgaaaat aattaatatg gggtgaagaa ccatgaatga gaataagatg gtattaagtg
     4921 aatacgcaag attgagaacc attaattggt tgaatggtat gcaaagtagt ggcgcttttg
     4981 atggatttga tgaggagaat atggactttg aaagtttatc gaatgaggat attagatatt
     5041 attttatcga atggtatttt acagaaccag atgaagaggt ggaagatgaa ccagaattaa
     5101 ttttagaacg tcaaagaatt ttattcagtg aacaagatag taagaggttg tatggtttat
     5161 atgacttaca actgaaagga ttaaaagcgc agtatgttgc tgatagttac gatgatatgg
     5221 tagaacaggg ggcagatagg gttgtcactt attcagaaga tgatgaagag gaatgggaaa
     5281 actattcaga tgatgagata tgctttaatg atgggtatat gcctattgaa atcaccgaag
     5341 aagaatatga taaagtgtcg gatagcgatg agattggtat gtgtacggtt gtaagtggat
     5401 tggatataga tgtccaaaga gtagaggttg cataccagaa gatgaaagaa cgtataaaaa
     5461 gtaaagtaga atcttgattt gattggattg tttgcaaagt agctaattaa gagtataata
     5521 taatcataaa tgtagttaat ggatataata atgagtatat tatactcaaa agaggtgaac
     5581 gaaatgaagg taaaaaatcc aaaagaaaaa agcagaattc aagtcggaat agacaaggat
     5641 ttaaaagaaa acgcagaaat gatattggaa gagctagggt taaatccaac aacagcaatc
     5701 acaatccttt ataagcaagt ggtcgctaga ggtgagtttc cagtagagat aaagctaagc
     5761 gaagaggaaa agcaaggaat cagattgcaa cagctaacta tggatatgcc agttgatgtt
     5821 ctagatacag atgaaaagtt agaagagtgg ttcaatgaag cctaatgaga tagtaacggt
     5881 ctatgttgca tttacagata aaaatggtgg taaaagaaga cctattttgg tggttagtga
     5941 taaagaagat agagtagaat tttttggaat cacaagtcaa tatgagaata aatcagacca
     6001 aataaagaga gtgtattttc ctattgcaga atgggaaaaa gtaggtctaa agaagcaatc
     6061 atggattgac gtagggtctt taaaggctat tcccaaaagc cgagagaaca tatcatttaa
     6121 aaaggttggt atgctatcag ctattgatac gaaaaagcta aataggttta tcgagagatt
     6181 acaaagaaaa gtctaacaag gcttttcttt ttttgtttat atgtatatta agatatacgt
     6241 ttatataaac gtatttatgt atattaaaat acacgtaaat atatacgtga ttataaaaat
     6301 taagaaaata ttaagtattg ttaaatagtg ataattagta atatacgaat cataagatac
     6361 attttatatt taatgtatgt aaataaataa aatgactgac ggatattgaa tagtaataaa
     6421 taacaataat tcagacggat acagtgagtg aagtagcttg ctacgaacga acaggcagaa
     6481 tgaaacggta gtttcattag agcaagtcgc ttgcgacgta gcgttaccac tgatgtaact
     6541 ggcaagttac atagagagag tttgcttgca aacgaacgtt acccacttga atagaaaaca
     6601 aaaataacat attagtgaat tttgaatagg agccacaact caaccaaccg cttgcggtgg
     6661 gtgagtccca cggaggaaaa gacgaacgaa cggtcgcgta gc
//
LOCUS       DAFLWQ010000120         6576 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.123, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000120 DAFLWQ010000000
VERSION     DAFLWQ010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6576
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.123"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..677)
                     /locus_tag="L1V16_002720"
     CDS             complement(<1..677)
                     /locus_tag="L1V16_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HBN1277000.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFKKKHKHVLEAIESIKRSVENS
                     ANVEDVLNFEQMFVEGNEPDSYGRNRRVYFMNRDGFSLLAMGFTGSKAINFKLKFIEA
                     FNEMEDVIRKNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNM
                     KVMEVLGGKESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLP
                     ETAIRME"
     gene            730..1206
                     /locus_tag="L1V16_002721"
     CDS             730..1206
                     /locus_tag="L1V16_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277001.1"
                     /translation="MRKKLNYILTATLTIYIILFITLSFLSSIKKIPFITLNKNSILK
                     EFNNIDYIAFLKLFSVCVLISCVIIFIVAKTCWTMLNKNQRDVENIAIFLIKITSSIS
                     IIIPMTVTFSKEQFNVAATYLSFIALFSFVLPKRNKSNFDNKELDEVRNSSPKEQK"
     gene            complement(1223..1393)
                     /locus_tag="L1V16_002722"
     CDS             complement(1223..1393)
                     /locus_tag="L1V16_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277002.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEYRAKKPVGRD"
     gene            complement(1398..1718)
                     /locus_tag="L1V16_002723"
     CDS             complement(1398..1718)
                     /locus_tag="L1V16_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HBN1277003.1"
                     /translation="MQYLEAKIPVPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRR"
     gene            complement(1734..1937)
                     /locus_tag="L1V16_002724"
     CDS             complement(1734..1937)
                     /locus_tag="L1V16_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1277004.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            complement(1952..2698)
                     /locus_tag="L1V16_002725"
     CDS             complement(1952..2698)
                     /locus_tag="L1V16_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBN1277005.1"
                     /translation="MNTPQIFSFEQHEVRTFLENDIPYFVANDVAKTLGYKNPSKATN
                     DHCKKSIETWGNDSLGRRQKFKVIPESDVYRLIIKSNLPSAEKFEAWVMEEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            2779..2958
                     /locus_tag="L1V16_002726"
     CDS             2779..2958
                     /locus_tag="L1V16_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277006.1"
                     /translation="MNKKTDEIAADLVVAWLNHESQVSTKGESISPKEIAQAYLDIHY
                     AVIYGQLPEDRKNDD"
     gene            complement(2955..3095)
                     /locus_tag="L1V16_002727"
     CDS             complement(2955..3095)
                     /locus_tag="L1V16_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277007.1"
                     /translation="MEKTVSAKIEDLKLDILKQAKVAMEHAVDKEDSAMVAAIAEILA
                     HV"
     gene            3394..3714
                     /locus_tag="L1V16_002728"
     CDS             3394..3714
                     /locus_tag="L1V16_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1277008.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            3732..4163
                     /locus_tag="L1V16_002729"
     CDS             3732..4163
                     /locus_tag="L1V16_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBN1277009.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            4293..4754
                     /locus_tag="L1V16_002730"
     CDS             4293..4754
                     /locus_tag="L1V16_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBN1277010.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            4788..5423
                     /locus_tag="L1V16_002731"
     CDS             4788..5423
                     /locus_tag="L1V16_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HBN1277011.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            5536..6171
                     /locus_tag="L1V16_002732"
     CDS             5536..6171
                     /locus_tag="L1V16_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277012.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            6470..>6576
                     /locus_tag="L1V16_002733"
     CDS             6470..>6576
                     /locus_tag="L1V16_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
                     /protein_id="HBN1277013.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKG"
BASE COUNT         2227 a         1100 c         1041 g         2208 t
ORIGIN      
        1 atttccatgc ggatcgcagt ttctggtaac cacatttcaa taaatgaaac agcatcatcg
       61 aatctcttac gaggtaactc gccatatctt gggattgaaa aggtacgttt aaattcagac
      121 caaaattttg agaatacttt tttgctgatt tcttcataag ctcggctttc ttttccccct
      181 agaacttcca taactttcat atttcctttt tgcttaattt caaactcttg ttgtccgcta
      241 attcgcatag tatctttaag catggaaaca tcttttttaa catctttcat ttcttctaat
      301 tgatagatca tcatgtcttc aattgtttga ggaacagtat tcttccgaat aacatcttcc
      361 atttcgttga aagcttcaat aaattttagt ttgaaattta ttgctttact tccagtgaat
      421 cccatagcta gcaaggaaaa tccgtctcta ttcatgaaat aaactcgtcg atttctgccg
      481 tatgaatctg gttcattacc ttccacaaac atctgctcaa aattgagcac atcttcaaca
      541 ttggccgaat tttcgaccga tctttttatt gattcaattg cttctagtac atgcttatgt
      601 ttctttttga aactttctgc cacttgtaag ctcgtagtta cagcttcttt atttttcaaa
      661 attactaatt cttgcattat ttcttctctc ctttttggta taattttcgt tagaaagtga
      721 ggtgattcta tgaggaaaaa gctcaattac attcttactg cgactttaac catatatata
      781 attctgttta ttaccttatc tttcctgtct tcaattaaaa aaattccttt tattacattg
      841 aataaaaata gtattttgaa ggaattcaat aacattgact acatcgcatt tctaaaactt
      901 ttttcagtct gtgtgctaat atcatgtgta attattttta ttgttgctaa aacatgttgg
      961 acaatgttaa ataaaaacca acgcgatgtt gaaaatattg ctatattttt aattaagatt
     1021 acttcctcaa tatcaattat cattccgatg actgtaactt tttcaaaaga acagtttaat
     1081 gtagcggcta cttatctttc atttatagcg ctattttctt ttgttcttcc taaaagaaat
     1141 aagagcaact ttgacaacaa ggagctggat gaagtacgca atagcagccc aaaggaacaa
     1201 aaataaaaaa atcatatttt agtcagtccc tcccgactgg ctttttcgct ctgtactcag
     1261 cttcatcaag ccccataaaa atccagacca tgtaaacaat cgttcctatc aacgcttgtc
     1321 tgcttcccca aagtcctaaa gcgtagatga ttagtggtgc gctgaatact aatgctctgt
     1381 taaattttcc catccgctta cctccttaag atttccgaaa aatttgtttc taaaaattca
     1441 agtgttttac ttcttaaaaa tagatatgtg tctcttcctt caactggata atagacaaat
     1501 ccatttttat ttttttcgat atcgataata tttctatatc ttgggttctt taaaactcta
     1561 gaagtaaacc aatcatattt tctgttaatc cgttctagca cttctggcaa cgtcatccat
     1621 ctaccagtat catcagcttt ttttaactcc tcataatcca cttgagagat aattacatag
     1681 ccttctggaa ctgggatttt cgcttctaga tattgcatta gctgttcctc cctttacaat
     1741 tcgtacatag tgataatcga atctataatt ctatttgctt ctgcagaagt ctttttaccg
     1801 tttaaaatca aagataagta gcttttgcta ataccgaatc tttcagcaag catggtgtaa
     1861 gttaagaact ttgaactttc gacatattct ttgatttttt ctctatctcg ttgagtgatt
     1921 tctgcaatgt cagtcatact aaaactcctt tctaaccaat ttcctctaaa tccatttgag
     1981 ggtaatagcc ctctgcgatt aataagttgt aaataaacac tcgccctttc tgtgtccatt
     2041 tggtattcat tacaacttta gtgccgccat cggctttcgg aatctcactt gtgtgcgatt
     2101 ttgtgtatcc ttggttcata tgttttcggt aaagtatcca ttgtccgcta actttatgtt
     2161 gaacacctaa ctcgtttagc aatttgttta gagcaattgc cgacattccg taatcagctg
     2221 caatttgaga agtagctacc gtatctgtcg atgaaagaat cgtatctaag tagctaatct
     2281 ttggttcgta ctcggcaatt tgttgttcga gtaattggtt cttttcttct aaatctgctg
     2341 ctaaacgcaa tgcttgtgca aaactttgag gtacgtttga atagctacct gtttttctga
     2401 ttgttggaag gacttcttcc attacccagg cctcaaattt ttcagcgctt ggtaagttcg
     2461 atttaataat caagcggtaa acatctgatt ctggaataac tttgaatttt tgacgacgac
     2521 ctaacgaatc gttaccccat gtttcaattg attttttaca atgatcattg gtggctttac
     2581 tgggattttt gtatcccaaa gttttggcaa catcgtttgc tacgaaatac ggaatgtcat
     2641 tttctagaaa cgttcttact tcatgttgtt caaaactaaa aatttgtggt gtgttcattt
     2701 ttgttcattc ctttctttga tataattttc ttatcagtaa gtggtctact gaaataatgc
     2761 ataaggtggt gaataagtat gaataaaaaa actgatgaaa tcgctgcgga tttagttgtt
     2821 gcatggctaa atcacgaatc acaagtatct actaaaggcg aatcaatttc gccaaaagaa
     2881 attgctcaag cttatttaga tattcattat gctgttatct atggtcagct tccagaagac
     2941 cgtaaaaacg atgactaaac gtgagctaaa atctctgcta tggctgcaac catggcagag
     3001 tcttctttat ctaccgcgtg ttccatcgcc acttttgctt gtttcagtat gtctaatttc
     3061 aaatcttcga tttttgccga gactgttttt tccatattct tctctccttt cttttatatt
     3121 cgtaaacaaa tttaacaact tttttctaaa ttcaattgac agtatctgag taatactcta
     3181 tactaagagc ataattaaat aagacataaa aacattgatt ttaaagcttt cttggcggtc
     3241 tgcatttaca tatcaatagt gttttttgtt gtctttttag ttgttaaatc tgtttacaag
     3301 atatagtata gctcattact cagaattagt caaattattt ctgcgtattt ttctaaactt
     3361 tttttgtaaa catttagaaa ggttgtttta tcgatgaata cctatgaaat aataaaagac
     3421 ttggcgaaga ggaaaaagat atctatacgg cagttagaaa ttaattttgg atattctaac
     3481 ggttatctag caaagtggaa aaataatact cctaattcag atgaattaag tcggattgct
     3541 gactatttcg atgtctctgt agactacctt ctaggtagag aagaaagaga aacccctaaa
     3601 catgtggatt tatcagaaga cgatactgtt ttttcttttg atggaaaaga aatatctaag
     3661 gagacaatgc gtaaagcgat tgcaattgct aaagctttag aggaaaatga atagttggag
     3721 tgatggtttg tatgtatttg aaattgaaag aaatgttgag cgaatacaat ttgaaagtag
     3781 tttatatgga gatgaaagag cctggtttct actatccaaa acccagaatc atttttttga
     3841 atgaaaatct atacggtgaa actgcagaag cctttcattt atctcatgaa cttgcacatt
     3901 tcagcgcctc tcattttgaa ttttcagttt tgtacgatac ttctacaact tttcactcaa
     3961 aatttgaaac agaagcagat aaaatagcta ttctaatttt attaaatatc tatattgaga
     4021 acgaactgac tgatgaatct cagtttaatc tcgaaaaatt tatggagtat tattctattc
     4081 agaataagct cagatacact tgttatgctg tctgccaatg ctattttaag aaaaaatatt
     4141 cttacgcaag gcaatatgta tgaatacatc aagaattatt aaaaaaaccg atttcagcaa
     4201 aacattaaaa aagcccgtgc tgcaacacgg gctctttcct catatatgag cttctacaaa
     4261 aaaaatcata tcacagaaat gaggaagaaa aaatggaaaa agagatttta ataaaatctc
     4321 caggaaaaac cttgattaaa gtaactgatg attctatttc aattattaga aaaggattta
     4381 taaatttagt taatcaaggt attaaaggag aaaaaactat cccctttaaa aatatatcag
     4441 ccgtacaatt aaaaaaacca ggtatgagta atggttatat acaatttacc ttgctaggcg
     4501 gaaacgaaag tcgcggaggt atattagcgg ccacgaaaga tgaaaacacc gttatgttta
     4561 caaaaaaata ttggaatgaa atggaaaatt taaaaaaata tatagagaag caacaatcta
     4621 tattagataa taattccaaa gaaacacaaa tttcaagtgc agatgaaatt aaaaagtata
     4681 aagagttgtt agatgaaggg attattaatc aagaagaatt cgattttaag aaaaaagaat
     4741 tgcttggttt ataatattca atatcaaaag agaaagagga tctattaatg gacggtatat
     4801 ttggttttac tggtattgtt ttatttatta taggtttaat catgttaatt gtaagattta
     4861 tcaaaaaaac aaataagaaa acacctatga ttctccttat tatcgggatt atttttacta
     4921 ccgtaggttt ctcgctttcc tcatcaaacg aggcaaatga caataacaaa caggaaagct
     4981 catcatctga tactcaaact actacatcta acagcagcaa taaaagccta actcaatttg
     5041 aagaattttt agagacaaat aatcatgact ggggtgcttt cttagatagt tattattcta
     5101 ttactccagc tactgagcaa aatacagctt ttactaaata tattagtggt aaaacatata
     5161 cttttgaagg aactgttatc gaatcaatga ctactagaat agccattata gcagacaaag
     5221 agtacgatga taaaagttgg aatgatattt ctgcaacacc taaagtttca tatgtaattt
     5281 ttgcgaagga cttaaacaat gctgatacct ttacaaaggg cgataaagta acttttacag
     5341 gagaaattag ttcaagagga tcgaacatag aaaaatccta tgctcaatgg gatatgatta
     5401 atagtaaagt aagtaaaaaa taaatgaacc acgccccact aagagttaga ttgtgcacaa
     5461 taataaaacc tatacaaaag agtgccatca ggagtcacaa tgcttgtaaa ggaaatgaca
     5521 aaataggagg taactatgga taatagcaat gaaaaactaa ccaaaaaaga atatcttgaa
     5581 ttaatagttg aaggcggtat tggagcaatt ccttatattg gtggcgttgt gcagtcactt
     5641 tattttgggt ctaaaaacga gaagcgtttc aaacgcatcg agaaattcta caaaaattta
     5701 aacgaatcat tagaaaacat tcgcgatcaa attccagaag atgttttcaa cttagagaac
     5761 aaggaccaac tcattggaat attcgaaggg ataaatgacg aggtagaaaa atcaaaggca
     5821 caaaataaaa tagatatgta taaaaatctt tataagaatt gtttacttcg aattaacaac
     5881 gcttcatggg ataacgagga gtattatctt cttgtactga atcaattaac atcgattgag
     5941 attcaattgt tagcatgctt aatgagtcgt ggaaacgaaa atttcactgg aaatatcagc
     6001 atgtctggct attcacaaga gctaatagat ggtagcttaa atagattatc tgattttggt
     6061 ctgttagaaa aaacgattag ctccatagta ttaggtgatg tcggcaaaca aaatatgggc
     6121 tacaaaatat ctcatttagg aattcaattt attaactcaa ctcttactta agttttcttt
     6181 ctaatatgac atctagacct atcagcaatg caacaataaa aaaccagaca taccaataat
     6241 caacaaataa tctaaactct ggaagttcag ttattctttt aaaaatcact ttaatcataa
     6301 taaacacctc tgattggatg atctaataca catccaatta taccattaaa acgacaaata
     6361 gcacatcctt gcgccggcaa gcaaaaagga tgtgcaaaaa ataataaaac ccaaacaatg
     6421 ggcttcttta tagttcctat tgtatcagag aaagagagct gattcaatta tggcaagatt
     6481 agtcaaacgt ggaaatagtt ggcaatacga aatttcatac aaaaaagatg acggaaaata
     6541 cacgaagata agaaaatcag gatttaagac aaaagg
//
LOCUS       DAFLWQ010000121         6346 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.124, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000121 DAFLWQ010000000
VERSION     DAFLWQ010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6346
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.124"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            290..1135
                     /locus_tag="L1V16_002734"
     CDS             290..1135
                     /locus_tag="L1V16_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1277014.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1416..2636
                     /locus_tag="L1V16_002735"
     CDS             1416..2636
                     /locus_tag="L1V16_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HBN1277015.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2633..5353
                     /locus_tag="L1V16_002736"
     CDS             2633..5353
                     /locus_tag="L1V16_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1277016.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5337..6281
                     /locus_tag="L1V16_002737"
     CDS             5337..6281
                     /locus_tag="L1V16_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBN1277017.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2363 a          982 c         1224 g         1777 t
ORIGIN      
        1 tttaaatctt ttgctaagtt gaactaatag agtcttttat gaatatcgaa gttagttttt
       61 cacctaactt cgttttttat agttggttat tataaaatag taatatagct gatttggatt
      121 caattcatat ttatttataa atcaaaaata cagagaatag tatataaatg tcctttccta
      181 ttcttaaaat gatgtttgta cttacttaaa ttaggtataa ttagtatatg ttttgtgaga
      241 aatttagact tacaataagc agtgaattta taatcaacgt ataggagaca tggatgaaat
      301 gaaactaatt ggtatagatt tagacggtac tcttttgaat tctgaccaga gcattagtca
      361 aaaaaatgca agaacaatga aacatttacc ggaagactgt tttccattca tttgttctgg
      421 aagagaagta gaagacatta ataatattct caaaaaatct ggtttaagga taccagcagt
      481 agggttaaat ggttctgttg gatttgatgg agaaaaaaag atatttgagt cttccttcga
      541 taaaaatgat gtaaaaaaaa ttgattctgt cctatcgaaa tttccaacca aaatatatac
      601 aaatctcgga agttatgaat ctcagaatta taaaaataaa atgaaaaaaa tttttcacga
      661 ggtagggagt gaattttcta tcaaagagct aaactatgag cttgagtatg aaaaatctat
      721 ttgttcaatc ccttataata atattgagga aattatagaa aaggatgcta tcagcattta
      781 caaatttttt atttttattc ctaatcgtca attgaaagct aatatattta accatttgaa
      841 aaagatgcta aatgtgtctg ttactgaatc ggcacctgta aatattgaaa tcgtacctca
      901 aaatgtatct aaaggtgtgg tgtttgatcg tttggaatca atctacaatt taaagaaacc
      961 tttgagaatc gcgatcggag atagtttaaa tgacttatct atgtttgaaa gtgcagatat
     1021 tagttttgca atgggaaata gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt
     1081 ttcaaatgat aaagacggag tatctcaagc atttgaaaga attcttacca tataaactaa
     1141 ttaaggtagt atagaacata gaattctaaa tacggaaaaa tggagcataa attccagtac
     1201 aaatagtact tcttcagtgt caaacgaagc gaatataaca tagatattta ggattgtgac
     1261 aaaaatcatg tcacaatctt tttttcgaat aaacttattt tttgaagtcg gccatttatc
     1321 gtaatttctt tgcataatac gaacaaattt tcggttattg atgaaaaaaa acattgaaaa
     1381 tggtatgata aaagaaaaaa aggaggaaat ttttaatggt gaaatttatc catgcggcag
     1441 atttacatat ggatcggtca tttgaaggac tgacaactct tgataaaact gtacaggaaa
     1501 aactattgaa gacgaatctg accgttttat caaatatcat tgaacaggca ataataaata
     1561 acgttgattt tgttttactt gcaggagata attttcatca aaatcgtcct tcattaaaaa
     1621 tacagaaaca tttttcagaa cagatgaaac ggttagaaaa gaaccatata cctgtattta
     1681 taatattcgg aaatcatgat ttctatcaaa aagagcggta ttggttctcc tttcctaaaa
     1741 atgtccattt atttacatcc gaaacggtag agacaaaaaa aataacgata aaaagtggag
     1801 aaactgtctc tctcagtgga tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga
     1861 tggaatttcc ttctagagaa ctcacagatt accatattgg gttgtaccac ggggaacctg
     1921 gcgtctctca aaaaggaaac tatgctcctt tccaaccctc aaagatgcaa gaaaagggat
     1981 acgattattg ggctttaggg catatccatg tgccaacggt cttaaatgaa aagcaaacaa
     2041 ttgtttatcc aggtgcgcct caaggtcata ctaaaaagga acaagcttct acatctattc
     2101 tactagttga attaagtaaa ggaagttgcc aaatacatcc gattaaagta gcagaggtct
     2161 attggaagac aaaggaaata tcattgagga aagcaagaac gacaaaagag gtcattgttc
     2221 acattcgtca gcagctttca aaagtagagg atggatttag tttaattgag ataaaattaa
     2281 aagattatga ccatctcaat acagatgttt tggaacggat acaatcagga gagctattag
     2341 actatttgtt agaggaattc tcagatagga taaatgattt ctttatttgg cgtatttctc
     2401 tcatagagaa tactttttat acgaagaccc cacttgctgc ttctgctaaa ttgatggaac
     2461 agttatttca atactatcag acacctcaag atttccaaca aattttaaat gaagtatata
     2521 gtcatcaaga agcggctaga atattgagcg aactgccgga atatcaagaa gaaacacttg
     2581 aaaaagccaa gcagctgctt aatcaagatt ttttatttga ggaggatcag gaatgaagat
     2641 tttaaggatc gagattgctg cttttggaaa atggcgtcaa aaaagttttg acttttattc
     2701 aggcaatcag ctgatctatg ggggaaacga agcaggaaaa tcaacgattt atcaatttat
     2761 tcaagcaata ttatttggtt tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa
     2821 agacggctca gcctatggcg gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc
     2881 tgtcgagcgc tacaagcagc aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt
     2941 gggaagtgat gagttactag aaaaactgat cgcacctttg acgaaagagt tattccagca
     3001 ggtatttact ttccagcaag agcagttgat ggaactagat catttgagag aaaaagagct
     3061 acatgatgcg ctgatttctt taggcatcac gggcagttct caagtattcc aaaagcggca
     3121 agaatattat cagaaagcac aacaattatt caagaaaaaa ggccaaaaat tactaatcaa
     3181 tcaaaaatta aatgaatgga aagagctgca agaaaaaatt catcaaaaac aagaacagga
     3241 agcttatttt ggcaagttga tccaacaaga acaggaatac gagtcgcaac agcagcagtt
     3301 attggcacaa ttaaaagagg cgaacaaaca attttcatta gccagacagc aagaacttaa
     3361 tttttcttta tatgaagaat ggcaatctct caaaaaaaac agcactacag gtcttcctga
     3421 tgagcaactt cttttagatc tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg
     3481 tttggaagaa ttagaagcaa cactggaaaa gcatagcggg atggatcagc agtcagccag
     3541 atattatttt tatttagagc aggagcagga actaaaagat ctccagcaac ttcaatttac
     3601 agcggaacaa ttaaacgaag aatggcaaag attacaaatt gagactagag aaacaaattc
     3661 agaattgaag attttggaac aaaggtggca ttggcagaaa aatccgttac cggaagaatt
     3721 tttatatgaa gaagaatgga agcatcttct ggctgaagaa agaaggattg ctgatctaga
     3781 aagccagatt tctgtgcgtc tccaaatagc taaagaacag caagagatga ttgaagcaga
     3841 agtgaatgac ttggaagaga cctatccagc attattacaa aatcagtcag agatagcacc
     3901 agtctcttca tctaaaccgt atatgctgat ggctggcgga gcaataatca ttgcaggtat
     3961 atttgtacca atgcccttga aagtgatcct tttactaatt ggtgcaggca tgattggcta
     4021 tttcttctac aaaaggcaac caaaaattaa aactaaaaat gatttctctg agataaaagg
     4081 aatgtggcaa gaaaaactag gacaacttga tctagcctta gctcaattag ctgaagcaga
     4141 agaaaaacaa aagagaactg gagaagaaaa acagattctt cagcaagaag tatatcgttt
     4201 tgcggatcat cggcacttag gaaagatgga tacgctcaaa ctcatgaaag aatatggaca
     4261 ggaagtcata gattatcaga aattatatgg cgtatttgag cggaaacata aaagagaaca
     4321 ggaaatacaa gaaaaactac gacaaatcga ccaaaaattt gagtttgtta aagaatggtt
     4381 accgatacaa gataagacaa tttcagaaaa aatggtattg ctttcccgtt ttatacaaga
     4441 gatggaacag atgaaatttg ccagaagcta tcagcaaaat actttattga agcaagaaat
     4501 caatcaattg aaaaagaaac aaaaagtatg gatacaagaa tacagcgaac aattgactca
     4561 agcaggctta tcttatcctt cggaagtacc tgtcttttta caaaaagcca aacaagccga
     4621 acagcagatg aaaagataca atgaattatc ggaaatgctt actccactat ttcctgaaga
     4681 gctgacaaaa gagaaattat ctgtaagact gcgccaactg aaagaaaagc aatcccaact
     4741 ccagcaagaa gaaaaagaag caagtgaaaa tcggcaacga ctccaacttc aagtagaaga
     4801 gttgcaaaga gacggcacat tggacgaact ttatcaacaa gctagccggc aaaaagcaaa
     4861 attacaggaa ttactggagg aatggggagc acttgaaatc gccgggacat tcttaggtga
     4921 tctttcaaca gagatgagtg aaagacaatt accccagttg ttaagagcag caggtgatta
     4981 tttaggtatt ttaacaaaag gaaattatca gaagatatta ctgaaaaatg atacactgac
     5041 tttaacagac ggatatacag aatttcccat ctatgagtta tctacaggta cgaaagatca
     5101 gctgattatg gcgatgagat ttgcttacct ctcattagaa gctaaccgtt cgatatgccc
     5161 gatcatcatt gatgatggct ggcttcatta tgatcatcag cgaaagtatc aattagctga
     5221 acttttagct aaatttggag aaaagtatca aataatttgt ttttcttctg ataaagaaat
     5281 ggtaagctat taccatgaga tgaaccaaat cgtaaaacaa ttagaaggag caaataatga
     5341 aaaaaattcg tgatttagta atcgatgagc agtttgaaca atttgtcctg atcaaaagtg
     5401 cagatgtaag aatcgctaaa aacggaaaaa aatttattgc ttttactttc caagatactt
     5461 caggtactat cgatggtaaa tactgggatg cttcggagga ggaaatcaat aaatttacag
     5521 ccggcacagt cgtttttcta aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa
     5581 agattcttca tatgcgctta acaagggtag atgagccagg agagcctagt ttatacatgg
     5641 aaagagcccc tttgaagaaa gaagaaatgg aagaagaaat caatcaattg ttgtttgaga
     5701 tcaccaatgc gcattggaat cgtattgttc gctatctact taataaatat caaaaacaat
     5761 tttttgagtt tccggcagca aaaagaaacc atcatgcatt tgccagtgga ttagcttatc
     5821 atactttgac aatgcttcac ttagggaaat caatcgccga tgaatatcct gagctgaatc
     5881 gagcattgtt gtatgctggt atcattttgc atgatttagg aaaggtgatt gaactttccg
     5941 gtcctatgtc gacagaatat acgcttgcag gaaatttgat cggtcatctg gtattgattg
     6001 acgaagaaat aactaaagcc tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc
     6061 tcgtattacg tcatatggtt ttagcacacc atggcttatt agaatatggc tcacctgtac
     6121 gtccaagaat aatggaagca gaaatattac atcaaatcga caatatcgat gcttcgatgc
     6181 agatgatgtt gacttcgatt cgtcaaacag aaccaggaaa atacaccgat cggattttcg
     6241 gtatggacaa ccgaagtttc tatgtaccaa aagatttata gcaaaaattt atttttttca
     6301 ttcaaaacaa aaaaagcgag acataagtct tcgctttttt tgtttt
//
LOCUS       DAFLWQ010000122         6300 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.125, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000122 DAFLWQ010000000
VERSION     DAFLWQ010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6300
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.125"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(60..278)
                     /locus_tag="L1V16_002738"
                     /pseudo
     CDS             complement(60..278)
                     /locus_tag="L1V16_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(544..738)
                     /locus_tag="L1V16_002739"
     CDS             complement(544..738)
                     /locus_tag="L1V16_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277018.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(838..924)
                     /locus_tag="L1V16_002740"
                     /pseudo
     CDS             complement(838..924)
                     /locus_tag="L1V16_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            2090..3130
                     /locus_tag="L1V16_002741"
     CDS             2090..3130
                     /locus_tag="L1V16_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBN1277019.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            3954..4286
                     /locus_tag="L1V16_002742"
     CDS             3954..4286
                     /locus_tag="L1V16_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBN1277020.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4905..5246
                     /locus_tag="L1V16_002743"
     CDS             4905..5246
                     /locus_tag="L1V16_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBN1277021.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
     gene            complement(5483..>6300)
                     /locus_tag="L1V16_002744"
     CDS             complement(5483..>6300)
                     /locus_tag="L1V16_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBN1277022.1"
                     /translation="TRYQLIKQLIRTKQHFLENLTYKCNTLAREMRDESTSLFSATLI
                     SLMTEDFTLDELAELPLEAFCDLLQEKGKGRFKQPEKIAKAIQRAITMSYRLGALAQE
                     SINVVLSVLVREIRALEKNIKELDKAIEQVIVVIPEYQCLTSIPGVGKVYAAGLIAEI
                     GQIERFEDQTKLAKYAGLSWKVNQSGNYQSQNTPLTKQGNRYFRYYLVEAANSVKNYL
                     PEYKAFYQSKYKEVPKHQHKRALVLTARKFTRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT         2206 a          893 c         1087 g         2114 t
ORIGIN      
        1 ggtattttta ttatatatag atttaacata tgtcggtcgg ttgattgata tagctaaagt
       61 tataactcaa ccgaagccga ttcatctaca cgaataaagt tgcgagtgtt ctcggctaat
      121 tcataaaaat tgttatgtgt tccatatagc aatactggaa taactttatt ttcttgaatc
      181 tcataagcaa ctctatacac ggtgaccgca tacttaaatc cattagacca attacctgat
      241 aaacctccag ttttttgctc ttacttaaat ggatcaatgg caatttcatc acaaacctat
      301 agaggatgag tgacttctgc ctaattacgt taaaaaatat tgaaagtaac tctatgtagc
      361 aaaaaatatc tagaatttca tttcctcaaa actgatcgat attgtatcta aaaatatata
      421 ctacctaaaa taggtagtat atattaaaat atgtgctttt gttagaaaaa tcaatacata
      481 aattatcata tctgtatatg tcatttaggt atttcagtta tgttataata gttttgctgt
      541 ctgctacccc ggcctaatct ggcaagggga ggaggagata taatgaaata cctttttgat
      601 tttgtttttg caatcaagcc acttgcagat gtagtgtgca gttacctctg caaatggctt
      661 gattgcaaaa ttgccaaaaa agacagtaag cctacccgtt aattctataa tatagaaacg
      721 taaaaaaaac cccatcagcc tgcacgctga tggggtttgg tgatataatg aaatacctct
      781 ttgttactca taattatacc ataattagtc acgaatgcaa ccaatagaaa aaactactta
      841 gaacggtaga tcatcgctaa taacaatgca ttgtccacca aatggatttt gtgaagcatt
      901 aaatacattg ttattaattg tcgctgcttt taactaggcc tctccccttc tattataaaa
      961 gaagatatat atcatttctt aattacctac taccttaaac caaaatttaa gtactaccta
     1021 atttaagtag tacttaaaca atctaaaaaa tagttatccc aattgttatg cttttataat
     1081 acgattattt gtaacaaaat gaatattata taattaaaca ctaccatatt taggtagtgt
     1141 ttaattatta gcaaaacaaa aaatatttat tctattctct taacttcaac taagttatgc
     1201 tgcacacctt tatataaatc atatgcaact cattagctag acaaactaca agcatgtagt
     1261 tttatctgtt aattatgtac tacctaaata aagtagttta taattagcaa gtatatatat
     1321 ttaaaaattt aagattaatt tttttatgac ttgtacaaat ttatctgata ttctcttatt
     1381 aagaactacc taatttgggt agttcttatt ttttacattt taagtagtat ttaattgcaa
     1441 tttggtagta tttttttatt atcttattct tagaacggta gtacttaata taaatatagg
     1501 tagtatctaa tttaagtatt aatggtagta tctaaattaa caggtagtat gtaactactt
     1561 taaagtaatt tttttcagat taacacagta gtatcttatt aaataagtta attttaatgg
     1621 tagtacataa ttattatata tatctgacat tggtagtact tattgtattt tttagtagta
     1681 tataatctat tgttttctag cctaaagcct tgtcttataa gaataatata atatatacta
     1741 ctgaaataag gtagtatata ttactagtaa tggtagtatg ttttatatgc ataaggtagt
     1801 tcttaattta ttttttgttt tgacactggt agtacttaat tatctttaat tttaaaacta
     1861 aattttattc atacgttttt ctggtagtat ttaattataa ataatattta tttaaagtag
     1921 ttcttaatga ctttaaaggt agtacataat tcattttatt tctgatttta ggtagtattt
     1981 aattaaaaaa cagttttaat gcgtttgcat tttttattta tctttgctat tttcgaaaag
     2041 agtaggtaat tttacataaa taaaacaacg tgaaagtaga ggatctacaa tgactgattt
     2101 taaatttttt aaggcggata gagtttacaa cgaattattt tatcaatttc caaaagtctt
     2161 tattgtttct gacgaataca aaaaaatgaa agattcaact aagattgcct atatgctttt
     2221 aaaagcaaga ttagagatcg caatcagcaa acggcaaatc gatgaagaag gtaatgttta
     2281 ttttacttat acgacaaatg aactatgtag agtattaaac tgccaaaaac aaaaagcgat
     2341 agcaatcaaa aaagagttgg aatcctttgg tttattatta caaaagcaga tgggatttaa
     2401 caaacagtta gggaaaaata atcctaatag actatatcta gcagaattaa aagtctcaga
     2461 aaatgatatc tacttactcg aaaaatttga tagagagaat agggaaaacg ttgataaatc
     2521 agagggtatg aaaatcatac ccaccctcga cgaaaaatca gacgctgaat cccttggggc
     2581 tcaagagggt atgaaaatca taccgtgcca aaacgttgat aaatcagagg gtatgaaaat
     2641 cataccagaa cttaataata atatattaga cactaataga cacaatatag acactgaaaa
     2701 agaccgccta caagatcaat tgttgttaga caattttgag acaattatga caaacgacag
     2761 cattgctacg tttgtccctg aacgagtatt aaatttgata aaaacatttt cttcaagtta
     2821 cagtgaagct caaaaaaccg tccagactat tcataatgca aagaaaaaag ctgaaataga
     2881 aagtgatatt tcgatagttt ttgaagaact cgatagttat tatgtcaatg cagaacaaga
     2941 attatacacg acactgttaa aagcctatca aaaattaaaa accgaaaaag tcgaaaatat
     3001 ccagaacctg atttttgtct atgtaaaaaa ttggtttatc gaaaaaccaa tagctgctaa
     3061 agtatcaagt gaaaaacgtt tgaattatgc aagctcccca agcactatta cgaaagactg
     3121 gttagagtga aactttactg acaaagtgat tgttgcttca tggagtaaca ttaaaattaa
     3181 aaatttttta ttattctaat tatattacga atattacaaa ataatagcta ttttaataga
     3241 atttataagt taaaatatta tgataaaaat cacaaacgta gccttttacg tcataagtgt
     3301 taaaagaaat aattaatttc aaatatagaa aagggaacgt atgtttgcat actccttttt
     3361 tttgagttat aataatacgc gaagagagat aatttcatta tttaaacaag ctaaaaatct
     3421 tgatattact tcttttcagg caatacgaat attattcgct tacatttttt gtataaattt
     3481 aattgtctgc tatgcttgtg atgaattgat tttcgttttg cacttttgga tgataaattt
     3541 ggacaattga aaatacaaaa aaaagaaagg cggtatgaac tcggaaggct ggtaaccttc
     3601 gtcagcgttc atacacggca ttaagatttg gcccttaatg cgttaacctt tcagtgttac
     3661 ggtattaccc gcaatggatt tagtataaca gatattcaaa agtgatacca ctttttttgg
     3721 ctgtgttaag gttaaaaata cgtgatatta cgatgaatct atgcctaagc ataatgttat
     3781 aaaaatgtcc gtgtggctct ttgccgtatg acgaacgctg aaattagagg gaacgcatgt
     3841 ttggatgcgt tccctctttt ttgtttgtca tgaacgaaaa tcaattctct atttttgaaa
     3901 aataacaaga aaaacttgtt aaaaatattt aaagaaattg ggtggtttat tttatgtcat
     3961 atacaggaat tttgagtctc aaagatattt gtcactacgg taaacggtgt accgctacag
     4021 agaaaatcac gaagaaacta tcaactggcc aaagtaaaac cgttgtgcag tgtaagaaat
     4081 atataatcca gaaagacaaa gtctcagagg aaatgattta ttacattggg aaacaaaagc
     4141 aaataatttt aaaagatcct atccccttaa aagagctata tccaacaatc aaacatgttt
     4201 atgaccaaaa cggtgtactg attggtcgaa gaaaaaatgg agtcttgcgt tgtaccgcaa
     4261 aagggatggg gcgtttgatc ggctgaattg atcattctca taacttgtat tttatcgttt
     4321 ttcgcttgct tgaaaatatt gtcgagactt ctaaaggaac ttagagtcac tagaaaaata
     4381 aggagtagac ttgatctatc aacaattccc ttcggggagt gacggggtag gttttaacga
     4441 ttggtaacgt aaaaaattgg tcaatcgagt aaatgcgctt gtttggatag tggtgaaatg
     4501 aatttgtgta aataataagc gcagagtaaa caagagggaa tttagaagtt agacaagtta
     4561 gaatagcgtc tagattaatc atgagcagct actaagggat ctagactttg acgcaaactc
     4621 atggaataag gagtaggtct tctcgtaatg gggaggacgc acaagaaatt gtgtcgtgtg
     4681 ctgcagtaca tgtagatact tgcgaggacg ttgattattg gatcaatcga gcatttaccg
     4741 ctgtctacta gggtttctcg tttcggacgc cataaacgag tcgaaatttt ttatgtattt
     4801 ttaagtaaac gaaaaacgat aaaatatgaa caagtcctga ataaagtgaa aaaattaata
     4861 taaagcatag agaaaatgaa atttacgtaa tggaggaatg acaaatgaaa aattatgatc
     4921 cgaatatacg attgggcaca catactatta aggtttcttt ccaacgttgg gattacaaag
     4981 gatttgtgac gtttagaagg ggcggaaatt gtaaaggatt agatgtttta gcattagacg
     5041 aggatgattt atacgatcaa acattgactg ataatccaat tggattcggc ttgctacctg
     5101 aagatgatga aggtaatgaa tggtttaaaa tgacgcttat gaatgataat ggagacgaat
     5161 tatctgttga agatacttgg tcatatttga gtgattatat tgtcagcttt gaaatcattg
     5221 aatttgtagc ggataaagaa gaataaaaac tggaggaata aattttacag ataaaggctt
     5281 agaaggagtc acgacgatta ataaaaaggt agtattacct taggcattga gtaaggaatt
     5341 tatttagtct aatggtgata agtcaagatg aaatttaaga ttttctttat tgagtaatat
     5401 gttttgaagc gcacgaaact agacccgatc aaaatcaaat ttttttcggg ttgattcaag
     5461 gatttgcgtc aataacggat tgttatttct ctatcacact ccttggtggc gtatagagtt
     5521 ggtgtttacg tagtagcgta tccaccagac gcgtaaattt tcttgcggtt aggacgagtg
     5581 cacgtttgtg ttgatgcttt ggaacctcct tatatttact ttgataaaaa gctttgtatt
     5641 caggaagata attttttaca gagttggcag cttcaactaa gtagtatcta aaatatcgat
     5701 ttccttgttt tgtcagaggt gtattttgcg actgatagtt tccagattgg ttcactttcc
     5761 aacttaatcc agcgtatttt gccaattttg tctgatcttc aaatctttcg atttgaccaa
     5821 tttcagcgat taaaccggca gcatagactt taccaacgcc tggaatactg gttaagcatt
     5881 gatattctgg aatgacaaca attacttgtt cgatggcttt atctaattct ttgatatttt
     5941 tttcaagtgc tcgtatttct cgtacgagaa cacttaaaac aacattaatt gattcttgtg
     6001 caagagcacc taggcggtaa ctcatggtaa ttgcacgttg aattgcttta gcgatttttt
     6061 ctggttgctt gaaacggcct tttccttttt cttgaagtaa atcacagaaa gcttctaaag
     6121 gaagctcagc aagttcatcc aatgtgaaat cttccgtcat gagtgaaatg agggttgcac
     6181 taaaaagact cgtcgattcg tctcgcattt ctcgagcaag cgtattacat ttgtacgtta
     6241 gattttcaag aaaatgttgc tttgtacgaa tcaattgctt aataagttga tagcgagtac
//
LOCUS       DAFLWQ010000123         6173 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.126, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000123 DAFLWQ010000000
VERSION     DAFLWQ010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.126"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            725..811
                     /locus_tag="L1V16_002745"
     CDS             725..811
                     /locus_tag="L1V16_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBN1277023.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="L1V16_002746"
     CDS             complement(932..1621)
                     /locus_tag="L1V16_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277024.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="L1V16_002747"
     CDS             complement(1628..1906)
                     /locus_tag="L1V16_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277025.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="L1V16_002748"
     CDS             complement(1866..2780)
                     /locus_tag="L1V16_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBN1277026.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="L1V16_002749"
     CDS             complement(2762..3142)
                     /locus_tag="L1V16_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBN1277027.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="L1V16_002750"
     CDS             complement(3592..3879)
                     /locus_tag="L1V16_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBN1277028.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="L1V16_002751"
     CDS             complement(3899..4123)
                     /locus_tag="L1V16_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HBN1277029.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="L1V16_002752"
     CDS             complement(4578..4748)
                     /locus_tag="L1V16_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277030.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="L1V16_002753"
     CDS             complement(4763..5296)
                     /locus_tag="L1V16_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBN1277031.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="L1V16_002754"
     CDS             complement(5317..6159)
                     /locus_tag="L1V16_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBN1277032.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1633 a         1152 c         1042 g         2346 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtcgatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DAFLWQ010000124         6021 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.128, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000124 DAFLWQ010000000
VERSION     DAFLWQ010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.128"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(119..499)
                     /gene="yajC"
                     /locus_tag="L1V16_002755"
     CDS             complement(119..499)
                     /gene="yajC"
                     /locus_tag="L1V16_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBN1277033.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(596..1741)
                     /gene="tgt"
                     /locus_tag="L1V16_002756"
     CDS             complement(596..1741)
                     /gene="tgt"
                     /locus_tag="L1V16_002756"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBN1277034.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            1959..2657
                     /locus_tag="L1V16_002757"
     CDS             1959..2657
                     /locus_tag="L1V16_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBN1277035.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(2825..5464)
                     /locus_tag="L1V16_002758"
     CDS             complement(2825..5464)
                     /locus_tag="L1V16_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBN1277036.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
BASE COUNT         1693 a         1322 c         1105 g         1901 t
ORIGIN      
        1 acacccgatt attcaatatt gagcaatata tcccatgctc ttatctcttt cttttttgaa
       61 taaaaaatga ggtaggacat ctttctgccc tacctcgtct ttaaataagc tttgatactt
      121 atttttcttc cttctcttct gtctcttcca gcgtttctgt tgtttcagtt tttacttcaa
      181 ctgtctcagc tggttcttct gttgtttcaa cagtagtcgt tgcatcattt gttacgacag
      241 tccctggttt gaccgttttg attgctgcac gatcgtactc aaggaagatc ccttcgcagt
      301 ctaaaacaac tgtccgtttg tcattgtcga tttctgaaac aactccatgt aatccgccga
      361 tcgttacgac tgaatcacct ggtttcatgc tatctaacaa gttttgacgt tcttgctgtt
      421 gtttcttttg cgaacgtgac ataaaaaacc acattgctaa tagcgcgata aacatcacaa
      481 gcattggtaa tgttcccatt tttttcacct cactaattct gtatctacaa aaaacacttt
      541 agcagaaaaa tgctgataac actagttttt tacttaattt ttaaaagatt ttcctttaga
      601 agctttttgc gttttcttta ttgaacccgt attcttcaaa aaaggcttct ctaaattcaa
      661 gcaaattatc atccatgatt gcttgacgta cttgtttcat tagattcaac aagaagtata
      721 aattgtggta agaagtcaaa cgaatcccaa atgtttcatc acatttgatc aaatggcgga
      781 tataggcacg tgtatagttt ttacatgtat aacaatcaca tttctcatca attggacgga
      841 aatcatgggc atatttcgca tttttcacta ctagacggcc ttgagaagtc atacatgtgc
      901 catttcgagc gattcgagta ggcaagacac agtcaaacat gtctactcca cggataacac
      961 catcgatcaa tgaatcagca gcaccgacac ccatcaagta acgtggtttg ttttcgggga
     1021 tcaacggtgt agtgaattct aatacacgat tcatttctga tttaggttcc ccgacagata
     1081 acccgccgat tgagtaacca gggaaatcca tcccgactag atctttcgcg ctttgacgac
     1141 gaagatcttc aaaccctgct ccttggatga ttccaaataa tccttgacgg tctggattag
     1201 catgagcttt caatcctcgt tctgcccatc gagacgtacg ttctactgat tttttcacgt
     1261 agtcgtaact ttcatcgaat ggtggacatt cgtcaaaact catcatgata tcagagccca
     1321 atttattttg gatgttgatt gctttttctg gtgataaaaa catacgcgaa ccgttcaagt
     1381 gatttttgaa atgcacgcct tcttcttcga tattccgcat atcacttaat gaaaaaactt
     1441 gaaagccgcc tgaatctgtt aaaatcggtt gatcccagtt cataaattta tgcagtccgc
     1501 cagcttcttc tactaagtct tcaccagggc gtagccataa atgatatgta ttacttaaaa
     1561 taacgccagc acccatttct ttcaactctt ctggggacat tgtttttact gtagctaatg
     1621 ttcctactgg catgaacatt ggtgtgggga aagttccgtg tggcgtgatc aattccccta
     1681 aacgcgcgcc agtatgtttt tctttcttga ttaaacgata gcgaatggca ggttgcgtca
     1741 ttcatttccc tactttctat ataaaatatc ttgacaactc ccaccatcat aatcgtttca
     1801 agtgcttttt gcaagttccc tcggcttcct tctactttat ttaatattct tttttttatc
     1861 ctttttttat gaataacaaa aaaaagaaaa acattatgac agaaatattt tttgatacat
     1921 ggtatattgg tgttattaaa gaaaaggagg gaaaaatcat gcaatcttct gcagaattaa
     1981 aacgccaagc aaaagagagt ctaaaaggac gttggggaca agctgtttta ctaaatctaa
     2041 tccctacatt gattggtatt gctactattc ttcttattat gattcctatt atcttgtttg
     2101 ccaccaccat atatgatgga tcagcgagcg tctcagaagc gacaacttca ggaggcggta
     2161 gttcaggagg cggtggcgga attatttcca gcatcattag cgctttgttc atgagcggta
     2221 tttcttggac ttatcttgat attttacgtg gacaaaaaga tcagatcgaa ccattcaaag
     2281 atgcatttcg tggattcaaa ggtttgttta tcggcggagt gatcagctta gctgtgctga
     2341 tctcgatctt tacaacatta tggggtttgc tattagttat tcctggaatc attaaaagct
     2401 attcttattc tcaaagctat tttatttact acgatatcgt ccaagaaaca ggacaaacac
     2461 ctaaagtact ggatacgatc actgcaagtc gaaaattgat ggatggttat aaaggacaac
     2521 ttttctggtt agatctttca tttatcggct ggcatatctt agcattagca actgctggta
     2581 ttggttatct atggctcagc ccatacattt ctgcaacaaa agcagcattt tatgaacaat
     2641 tgccaaaaga tatttaaaag agagtgtgac ttgtgaccga gggggtggca ggagaacacc
     2701 gtttatcgag aggcagtaaa agaaacattc agcccattag caaaaaggag gtgtgacaac
     2761 attcatgtca cacctccttt ttgtatagtt ccagtaaaaa gaaaatcaac ttagaaacag
     2821 ttaatcattc ctcttcttct gcttccggta atcgatggaa cttgatcagt tcattcaccg
     2881 cgattggtac gatagataaa atccctacca agaaccagtg attcaaactg atgtgtacta
     2941 ggccgaatag ttcttgcgta aatggcagca aagcaacagc cgttgtaata gctaatgcca
     3001 gtaacgccat ttctaccaaa gctttattgg tcgctaaatt gactttgaag atcgattggc
     3061 tgctgcgtac attgaacaca tgcagaatcg atgaataagc taagatcaag aatgcaacag
     3121 tttgaccgac atgctgactt gcgtctaccc atgggctgat agtatcgaca taactaccta
     3181 aataataacc aaacaaggtt acgatggtga agacccctgc atttatggca attttttgca
     3241 ataaacctcg agcaaagatc ccttcatttt tcggaatggg tggctgatcc atgatgccgt
     3301 gttccgctgg ctctcttcct aaagcaaatc ctggaagtcc atcagcaact acattgacaa
     3361 acagtagttg cacagctgta aatggtgctc cccatcctaa cagcatcgca atcaaaacaa
     3421 taaagatctc cgaaatatta cagcttagca aaaagttgat agctttacga atattctgat
     3481 aaaccgaacg tccttgactg acagcgtcta cgatcgtcgc aaagttgtca tccgtcaaaa
     3541 tcatatctgc ggcactttgc gccacatctg ttcctgtgat ccccatggca cacccaacgt
     3601 tacttgcttt caacgctggt gcatcattca caccatcccc agtcatcgct acgactgcac
     3661 ccgtacgttg ccaagatttg acgatccgga tcttgtcttc tggcgttacc cgagcataga
     3721 cagagagagc tttgacacgc gcatctaatt cttcgtctga taattgatgc agttctgatc
     3781 ctgaaagtgc ttctgacgga tcattcaaga tacctaattc tttcgctatg gcactggcag
     3841 tcaccacatg atctccagtg atcatgactg ttttgatgcc agcctttttc gctcgcttga
     3901 ttgctccttt actttctgga cgtggtggat cgatcattcc gatcagacca atcaaacgta
     3961 agtctttttc cagtgcttca gaagaaatat cttgcggttc ttcgtcataa gtagcataac
     4021 caacagcaat cactctcagt gcccgtttac caaagcgatc attaacgatc gccgcttgtt
     4081 ctacatcgcc tgaactaaag cgcggagcaa gaacatcgaa tgctcctttg gtgattgaga
     4141 tgtatttttc gcccatttgg tgaactgttg tcatcatttt tcgttcagaa tcaaaaggaa
     4201 gctcgtttac tcgtggatat ttttcttcta attctgcctt tgtatgataa ttctcttcaa
     4261 cagcccttac gatggctact tctgttggat tacctttgat aacaaggtcg tcatcttctt
     4321 gctcgaccgt cacatctgta catagtgcag ccattttcaa tatttccatc gcgctgttcg
     4381 tcattgaatc ttcgatattc gttacttcat cttctttgct ccatacccgg cggacgcgca
     4441 tttcattttg tgtcagcgtt cctgttttgt ctgagcagat aacattagcg gttcctagcg
     4501 tttcaactgc tggcaactgt cggatgatcg catgtttcct cgccatcttc tgcacaccgt
     4561 atgcaagtgt caacgtaaca ataacagtca aggtttccgg tacagctgca acagccaagg
     4621 aaatcgaagt catgaacatc tcaaggagtg gttctccttg cagttcacca atcacaaata
     4681 ctaaagccgc agccgctaaa gcgatcatac tgattcgttt gcctagctga ttcaatcgga
     4741 cctgtaaagg tgttttttgc atagtatttt cgttcaaaag atccgcgatc ttacccattt
     4801 ctgtagccat gccaatggca gtgacgatcg ctttcccacg acctgcagca accgtacatc
     4861 ctttaaatac catattaagt tggtcaccta atgactcatc ttcttcagca ataaatgctg
     4921 catctttttc aactgcttca ctttctccag tcaacgccga ttcttctaca cgtaattgtg
     4981 atgcttcgat caaacgggca tcggcagaaa tagcatcacc ggactctaaa acaagaatat
     5041 cacccactac cagttgctct gactcaacag tggtcacttt gccgtctcgt atgacagttg
     5101 ccgtttgttt attcatatct tgcaaggatt ccagtgcttt ttctgcgttt ccttcttgga
     5161 caatcgccaa taccgagttg atcacaacga tagcgatgat cagcagtcct tcaaataaat
     5221 ccccatgttc tgtagcaaat gcggtataaa aggaaatcac cgctgctaca agaaggatga
     5281 tcgttgtaaa atcggacaag cttcgaaaga attttttgat catcgattct ttcggcgcct
     5341 catcgaattt attcaatccc tgcttttttc gccgttcatc cacttcttgt gaagacaacc
     5401 cagtatctgg atctgcttct gttaccttct ttacttcttc tattgtctgc ttgtattctt
     5461 ccatcctatt cctcctttaa aatcttcgta caaaaaaagg tacttatttt actataacat
     5521 ccttttttta tttacttcaa ataaagggct tatcgattat ttgttaagaa agcgtaaaat
     5581 ttaaagtgct tatatttgca aacgctacca aaggatgcta ttatatagat gtaaggaagg
     5641 aggataccat caaatagaca gaagaatttc tcgatagaac agtgtaagca aacaaagttg
     5701 ttagaagtac aggtttcacc cagacatgcg tgtagagtac aaacctataa atagtgaatg
     5761 cgtatggatg tttggatcac gaagtatccg aaacaagaag taatgcgata cgtaacaatt
     5821 gaataacgta aacgtctgaa aattgaatag gaacaagaga tgtttcaaat gttgaagatg
     5881 taacgaaaac aaaatttttg tttaacatga agaaattcaa caccgtgctt tgcatgtatg
     5941 atggaaagtt acaatcattt ctgtttattt gaatccttcc gaggtacaag aaagccgagc
     6001 ttatcgagag ctcggctttt t
//
LOCUS       DAFLWQ010000125         5975 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.129, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000125 DAFLWQ010000000
VERSION     DAFLWQ010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5975
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.129"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            205..546
                     /locus_tag="L1V16_002759"
     CDS             205..546
                     /locus_tag="L1V16_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277037.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            539..1210
                     /locus_tag="L1V16_002760"
     CDS             539..1210
                     /locus_tag="L1V16_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBN1277038.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            1216..1902
                     /locus_tag="L1V16_002761"
     CDS             1216..1902
                     /locus_tag="L1V16_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277039.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            1905..2654
                     /locus_tag="L1V16_002762"
     CDS             1905..2654
                     /locus_tag="L1V16_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1277040.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            2666..2935
                     /locus_tag="L1V16_002763"
     CDS             2666..2935
                     /locus_tag="L1V16_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277041.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            2940..3104
                     /locus_tag="L1V16_002764"
     CDS             2940..3104
                     /locus_tag="L1V16_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277042.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            3097..3399
                     /locus_tag="L1V16_002765"
     CDS             3097..3399
                     /locus_tag="L1V16_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277043.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            3396..3557
                     /locus_tag="L1V16_002766"
     CDS             3396..3557
                     /locus_tag="L1V16_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBN1277044.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            3554..3859
                     /locus_tag="L1V16_002767"
     CDS             3554..3859
                     /locus_tag="L1V16_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277045.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            3859..4215
                     /locus_tag="L1V16_002768"
     CDS             3859..4215
                     /locus_tag="L1V16_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HBN1277046.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            4202..4420
                     /locus_tag="L1V16_002769"
     CDS             4202..4420
                     /locus_tag="L1V16_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277047.1"
                     /translation="MDLYDIESGATLSVESDHLIINFGGKRQIILWVVDDVLFPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            4417..4836
                     /locus_tag="L1V16_002770"
     CDS             4417..4836
                     /locus_tag="L1V16_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HBN1277048.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            4833..5390
                     /locus_tag="L1V16_002771"
     CDS             4833..5390
                     /locus_tag="L1V16_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HBN1277049.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
     gene            5387..5683
                     /locus_tag="L1V16_002772"
     CDS             5387..5683
                     /locus_tag="L1V16_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277050.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            5760..>5975
                     /locus_tag="L1V16_002773"
     CDS             5760..>5975
                     /locus_tag="L1V16_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBN1277051.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIETERDAI"
BASE COUNT         2233 a          940 c         1339 g         1463 t
ORIGIN      
        1 agactttttg gtgatgacaa tgaatagagc tgaagcgcta agaataggga cggcaattgc
       61 taattgctgg tggaaatact ataaaccaat catcctaagc caacaacata ttgacaagca
      121 aaaagcatgg caacaaataa aaaagtgact ccgccggcaa gcaaagagtc acaaagaaaa
      181 cacatcataa ggagatttta gcatatggaa aaagaacttt ccactctaga tcaatatttg
      241 attgatcctg attggggcaa gccgaaaatt gaggaaacaa gtggtcgaaa aatcagacga
      301 aatcttttga cgaatgaaga actagcttgg gatcaagatg atttaggcaa ccatgtaact
      361 atttgggatc atgtttatct tatccatcta tcgaagcatt cgaataaacc tgaatatatt
      421 tacgtcatcg aagatggctt gattgatgcg ctagaagagt acgacagaga taacttgatt
      481 gatatctctt attacggacc aggtaagaaa tacattgctg aaatggaggc agaatttgat
      541 gagtgaaatc aaagggacaa cgaactttga aaaacttttt agtcgtaagt taaataaaat
      601 tctcaagaaa aaaggaaatt ttgattattt atcttgggct cacgcgtggg agattatgaa
      661 aaagaatgat ccacaggcaa cggtaactat taatgagtac aaacactaca gggttgtttc
      721 tggaactcat caagactttc ttgttgagga atataaacct tttcttatgg atgaaactgg
      781 gacttatgta tctgtctcag taacggttaa aggacacacg gaaaccgaat tatttcctgt
      841 tttagattat cgaaaccaac cagttgttaa accaaatgca atgcaaatca ataactcatt
      901 gaagcgatgc tttgtgaaag cattggctct acacggactg ggattatatg tatttcaagg
      961 ggaagatatt ccaacaccac ctagaatcga tacaaagaaa ttaaacatgc tagagacgat
     1021 tctagaagct ttcaatgagc agatgggtaa agatatgacc aaaaccttaa tcgaatatgt
     1081 taatgagcag acagataaat tagggctctt agctgataac gttgaaacta ttgaacagtt
     1141 aagctatgag caatgtgcct tgatggagcg agcaatagca gctaagagaa aagaattaga
     1201 taagaagtga tatgagtgtt taaaccatta atcgattcat attcagcggt tctgaaaaag
     1261 ttcaaaggaa aagacataag cgcaaccatc aatgaggaag tgaacattga tcgactaaag
     1321 acgatgtatg acggctacga tggtgatcga gtcattgaaa ttcgttttat tgatcctaga
     1381 cgtttcaccg tacagcaacg aaacttcatc tatgcgctga taggcgatat ttttatcgat
     1441 acaggcatgc caacggactt ctggaaggaa ttcttctact ttcgttttga aggtgtcaca
     1501 gggcgcaaaa taagcctgaa agacgaatcg aatacaactg tgagtgatgc caatgtctta
     1561 gcaaatatca tcttagattt catctttgaa catcatattc ctttcaaaga aggctatgag
     1621 attttacctg cgaatcaaga atattacttc tacaaatgca tcacaaaaag agtctgctgc
     1681 atctgtggca aaacaggagc tgacatcgat cactttgaca aagcgctagg aagacgaaag
     1741 cgcaaagaag ttgatcatgc agagtacaca tttgcagcac tctgcagaat ccatcacaca
     1801 gagaagcaca aaataggtgt gattaatttc aaaaataaat atcaaatcaa agggatcaaa
     1861 ttaaaccaga aaacaatcaa aaagttaaat attggagggt aaaaatgaca gaacatcgaa
     1921 gttattatgc gattatacca gccaacgtaa ggtacgacaa aagacttaaa ccaaatacta
     1981 agttgttata cggagagata acggccttgt gtaatgaaag aggcttttgt tgggcaggca
     2041 atgagtactt tgcagattta tatggtgtga ataaagagac catatcgcga tgggtaagtg
     2101 atttgattaa gtttggatac ttgaatcggg aaatcattta caaagagggt accaatcaaa
     2161 taatcaatag gtacctacga attaatcaat accctattga cgaaaaacgc aataccccta
     2221 ttgacgaaaa agtcaaagat aataatacat ctattaataa tacatttaat aatacaaaag
     2281 aatatataag agagttaccg ccttcgaaaa aatcgaaggc taagcccgtc cgtcataaat
     2341 acggagagta taaaaatgtt cttttgtcag atgagcagat ggagaaactc aaaacagaat
     2401 tccctaatga ttaccaagag cgaatcgaac gactgtcaga gtattgtgaa tcatctggta
     2461 agacttataa aaactatttg gcaactattc gaagttgggc aaggaaagaa aaaagtgaac
     2521 ctaagaacgc aagcagtgga tacaagcgca caggaagacg agagaagctt cctgaatggg
     2581 caatcgacca agaagcctat ctcaagaaaa aagcgctaga acgagctaat agacaatcaa
     2641 aagcaccatt ctaagaggtg gaaaaatgaa gatcgattat ctagaactaa ttaatgaaat
     2701 agcgaattat aaaaagggcg aggaattaga cgtcctgaga gacgtatatg atcaactcga
     2761 agaagctgga attgaaggaa ttaagaatga tcgttcgagt tggagtaagc tcagatacta
     2821 tttcgcactt tatatcgata caacacaatt aagaaattta gcatatacca aattactatt
     2881 tgttgattgt gttaaaggct tgcaaaaaca tcttaatgaa cttgagcagg tgtaatcaga
     2941 tggacctaaa gacatttaca gcacagattg aactaatgca tcaagaagct ttaagacaaa
     3001 gtgtatcgta cgaagacaag tggctcaaca cgttccatgg cggacgtgag agcgcacttg
     3061 atcaagtact caaattactg aaaggagaat gtcgggatgg ataagaaagc ggcaatgcag
     3121 cgaattatcg aattgactta ttcagaagat tggcaaaatg acaaagaagc tgcttcagaa
     3181 gtgatgaggc ttggaagagc gatgtgggca gacaagagca acaagccaag accacgaaaa
     3241 atcgcaattt ggcacggtga caaacttcta gtgataggga cagctgaaca gttagcaagt
     3301 ctcacaggct tgcacgagaa aatcgtgagg aaaagagcaa ggtgtggcta cacagacgct
     3361 aagaagagaa cgtttagata cgtggaggaa tcatcatgac aacagaagaa gtgattcaaa
     3421 tgcgtattcg aagccttcag cgtgagattg acgatctgga acgaacaaag gcagtgatgg
     3481 tcaatgaaac ggcgagaaag gcaatcgatt tgcacataga gaatttaaga agggaaatcc
     3541 atcgattgga ggaatgagcg tggataagaa agcagcaatg aaaagaattg ctgaattaac
     3601 caagtcagaa tcttggcaag aagacaaaga aatagttgca gaagtccaaa agctcggtaa
     3661 atcaatgtgg actgaaaagc ccaaacggag aacgccgaga aaaattgcaa tctggcatga
     3721 tgaccgaatt ttagtaacag gtactgctga acagttatct gaaattactg gattaagcaa
     3781 aaacattatc tgggatagag ctaggagctt atggattgat tcaaaaggac gacagtttag
     3841 gtatgtggag gagagataat ggatctcatt acacaataca gtgacatcat cctcaagaaa
     3901 atcatgatga agattcagaa agataaaaaa tcaaaagaac gagctgaatt agttaagtta
     3961 gaaatggctg aaacaggagc aggagtgcga agtagcaggc attggaaagc agcagcaaac
     4021 attgaatttt attacaacga aattcaaaaa gggttcgatc agatgcgtga gctggatcgg
     4081 caaacaaatt ggagcaagaa acttcatcaa gatcgtttca aatttgtaga gaagtataaa
     4141 gaaatattag aagagtattt gaggaggaca gcaaatgata aaaaaactcg ttcaattcag
     4201 catggattta tatgatatcg aatcaggagc aacactatct gtggaatcgg accatctaat
     4261 cataaatttt ggtggaaagc gccagattat tttgtgggta gttgatgatg tactgtttcc
     4321 agaaattgtt catgatttcg aagaatcaaa agcggttgag tttgaaatag tgaaaaaagt
     4381 aatggaattg attgaaaaat acgaggagga cagcgaatga taccgaagtt tagagcgtgg
     4441 gataaacgaa agaacgtaat gagagatgta gccgtcttgc attttactaa aaacggcaaa
     4501 acaaacttta ttgaatattg gataaatcct accgaattga aatcatatca cgtgcgaaac
     4561 atcgacctca tgcaatccac aggaatgaaa gataagaatg gtgtggatat atttgaaggg
     4621 gatatagtat tagtcagcgt gcgaaatggc ttcgattact tagataataa agtctgtatt
     4681 gtcaaaaatt caatagatta ttccggatta gtttgtgcca ctgttgatga agacttagag
     4741 tatcaaattt ttaacacaga gctgtttgaa gaatacacgt acgaagtcac cggaaatata
     4801 tacgagaata gcgagttatt ggaggaacag cgatgaataa acaggaagca atcaaaaagt
     4861 tagaaagtat taaagcgata ggaaatgatg caatagctgc ttgctataac gagagtataa
     4921 attcaggtat tacgttaatg aaaaaaatag acgaaccgca gaaaccagtt attccacaac
     4981 tcgtggccgg ttggcttgag aaatctacgg acccttttac aaaagctgaa aaaatagcgt
     5041 atttaatcaa atctaaagat ggtgattcat attatttctg tgattggttt gtacgagatg
     5101 gcatagtgac gcaagagcaa ggagaagaat tactcgcttg ggcaacaaga caatcatatg
     5161 aaacactatt gagcctatac aacggctacg aggttgagaa agagccgtta tgggcaataa
     5221 agaatgccga tggaaactat cttactaaat gtgctttatg gggaaaagat ggagtaaatt
     5281 atagttttga atgcaatcca tctcatcgat tgcttttcac tgataaagca acagcggatg
     5341 ctgcagcatt gttggtgaat ggaacagtgg aagaggtggt agaaagatga aactaaaaga
     5401 cggattttac gctagcagtc acggtatcgg cggtttaatg ctagatatgc cgacaaagaa
     5461 ccctaaaaca cgcaagaaat caaaattcaa agtcggtgac atggtccgct gtgaagcaga
     5521 agagttcgtt tatccgttca gaggatacgt taaaaagata ctgtcaaact cagcaatcat
     5581 tcgtattgaa aatacaatga agtgtgatcg ttcgactgca aaacacaagc attatttagc
     5641 tgtagcgaga ttagttgaca tggaagtaat caagagcaaa taaaaaaagc cggatcgctc
     5701 cgactgattc aataaatcca acacatttat tatatcacat aaaggagcgg tttgacttga
     5761 tgcaattgtt acgagaggta gatttcaaac agacaagatg taatgcgaga gatgtgctga
     5821 agaactttcg gcgtttggag cggatggcag gtcgctcttt gatagatatt aagtcgccga
     5881 ttataacgga tatgccgaag gcaccgaagc atggcaataa ggcagaagac gcgattattc
     5941 agatgatgga tatagaaacg gagagagatg cgatt
//
LOCUS       DAFLWQ010000126         5911 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.130, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000126 DAFLWQ010000000
VERSION     DAFLWQ010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5911
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.130"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(137..595)
                     /locus_tag="L1V16_002774"
     CDS             complement(137..595)
                     /locus_tag="L1V16_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1277052.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(608..1939)
                     /locus_tag="L1V16_002775"
     CDS             complement(608..1939)
                     /locus_tag="L1V16_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HBN1277053.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(1950..3392)
                     /locus_tag="L1V16_002776"
     CDS             complement(1950..3392)
                     /locus_tag="L1V16_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1277054.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGVSG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(3379..4143)
                     /locus_tag="L1V16_002777"
     CDS             complement(3379..4143)
                     /locus_tag="L1V16_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HBN1277055.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(4247..5122)
                     /locus_tag="L1V16_002778"
     CDS             complement(4247..5122)
                     /locus_tag="L1V16_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1277056.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(5377..5461)
                     /locus_tag="L1V16_002779"
     tRNA            complement(5377..5461)
                     /locus_tag="L1V16_002779"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5425..5427),aa:Leu,seq:caa)
     gene            complement(5479..5550)
                     /locus_tag="L1V16_002780"
     tRNA            complement(5479..5550)
                     /locus_tag="L1V16_002780"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5516..5518),aa:Gln,seq:ttg)
     gene            complement(5560..5632)
                     /locus_tag="L1V16_002781"
     tRNA            complement(5560..5632)
                     /locus_tag="L1V16_002781"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5597..5599),aa:His,seq:gtg)
     gene            complement(5694..5778)
                     /locus_tag="L1V16_002782"
     tRNA            complement(5694..5778)
                     /locus_tag="L1V16_002782"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5742..5744),aa:Leu,seq:caa)
     gene            complement(5799..5869)
                     /locus_tag="L1V16_002783"
     tRNA            complement(5799..5869)
                     /locus_tag="L1V16_002783"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5835..5837),aa:Cys,seq:gca)
BASE COUNT         1811 a         1258 c          900 g         1942 t
ORIGIN      
        1 tcataggagc aacaaaaaaa ttcgataatt aacaaaaatc aaaatgatta aatctagtga
       61 ttgaaacata tcatttcaaa aaaattttgt aaattcaccc ataaatatca ccctatttaa
      121 cttttttcat cgtacactaa aattcaaaac aactatcttt aatctttact tcttggtttt
      181 gttttaataa atttccttca aaaatgcctg gagaaactac aatgatcacc gtatcttttt
      241 gtgcttgctc caacttcttc aaatctataa tagctaacag tgtcccttct tttacctcct
      301 ggttactttc aacccgtatc tgaaacggac ttccttcgag ttcaactgta tctaaaccca
      361 tatggatcag tatttttctg ccagattcac tttcgatcgt tatggcatgt cgggtaggaa
      421 atatattatc gattattcct ttaactggcg catggatata tccatcatga ttcgttatag
      481 cgtatccaac tcctatcatt tttgaagaaa agacctcgtc ttttactgct gttaatggaa
      541 taatttgacc actagctaca gcttttagaa tgtttcttgt tttaaagaaa tgcacttttt
      601 atcacctcta ctttaatgct ggccaatatt ttttgtttac tttgatcatt tcatctagta
      661 ttttttttgc gactctggca tttggtacgg tttgattcaa tgtaaatgct tgtaaagctt
      721 tttgataaga accttcaaag taagcatcta ctagtaactt ctctactgca acttgtgcct
      781 ccatcaatcc tttatgaaaa tcactgattg gttttcttag tgtaattggc tccacaccag
      841 ttgcaccaac atatgccggt atttcaacaa ctgcatctga ccgtagattc ggaatcgccc
      901 cttgattagg aacgattagc ataaagcgac gacgatcatc attcaacaag gaaatagcta
      961 tatcgacgat atattgtcca tgctccccaa aattaaagtt caatacttct tccacaatac
     1021 cgcggcgtat tttatcagcc atttctttgg tatttttctc tcgtccatcc atgaccatat
     1081 tagcacgtgt atactctttg tcagtatgct caacgaccat atcaggatat aagtaatact
     1141 ctaagtaatt attcgggata ttacttggaa aatttttcgt gatgactgac atcatttgaa
     1201 aggttttttg ccaagtttta tctcctatat taaaatcggc gacttgcatt tcttttgtta
     1261 ttagtttttc aataatctct ggcataattt ctcgttgcaa ttctttatca taaatcgatg
     1321 tataccagcc aaagtggttt aaaccataat acgtaacgat ccaattctta cgatcataac
     1381 cgtaattcac tgcaatcgtt tcttcaattg aaatagtcat atcacaggca ttaatcattt
     1441 ttacattcgg atatttacga cgaacagctt cagaaacgat cgactctgga tttgtataat
     1501 tcaaaatcca tgctttgggg gcatagtctt gtatatgatc gacaatttcc aataaacctt
     1561 tgattgagcg catcccataa gcaaatcctc cgagtccaca cgtttcttgt cctactaatc
     1621 catgtttaag tggaatcttt tcgtcctttt ctcgcatctc caatcctcca acacgaattt
     1681 gtgagaaaac aaaatcgcat cctgtaaaag caagctttgg atcatccgtt gcacgaatgc
     1741 gaatatttga aaaacctttt cttttcagca taaatttaac aatcaagtac atatccatat
     1801 ttctttcttc atcaatatca tataaacgta tttcagataa tggcaaccgt ttttcattgt
     1861 tcaaaatggc ttgaacgatt cctggtgtat acgtactccc gcctccagct atagtgataa
     1921 tctgtttttt catcatcatc ttttcctttc tattcttcta ataatttatt gaattctgcc
     1981 ataacataag tcacttctaa gccgatgata atttgataat ttttttcagt tggtttaatg
     2041 atcccgctta cccctaattg cttgattcgc tgttcctcga ccatggtggg atccactacc
     2101 tctacccgta ggcgtgtatt acaactatag acatccagga tattggcttt tcctccaaac
     2161 gcttgtagca tttttgttgc catatattca taatttttac ttgctaaccc taactctgtt
     2221 tcttctaagg ttacttcatt gccaaactct gccttagctt cacgtcctaa tgtctgaatg
     2281 tttctcttat tgatcaaata ataaaaagta acgtaataca aggcaaaaaa gaaaattccg
     2341 attggaagaa tcaaaatagc attggtagcg attcgaaaat tgatgagata atcaacaata
     2401 catgctccga atgtaaaacc aattcgtata ttgaataagt aacagacaat ccctgctaaa
     2461 ccggcaaaaa gtgcatggat cacgtacaac ataggagaaa gaaacatgaa actaaattca
     2521 acaggctcag tgatatttgc aataaatgaa gttcctgcac cgcttcccat gattcctttg
     2581 accatctctt tattttcttt ataagctgct ttatagatag ctagacatat agctggtata
     2641 ccaaacatca ttactacaaa aaaaactgat aaaaacagtc cagcctgagg atctccgttg
     2701 ataaagcgtg tcatctctcc tctgaaaact tccttgctag gagatgtata gcttcctaaa
     2761 tcgtaataaa tatacgtatt caacacatgg tgcagtccaa aggggatcag caaacgattc
     2821 aaaaacataa atatccccac acctaatgct cccatatcaa cgagcagttt tgcaaaatta
     2881 tcaatcccaa tttggatgag cggccagata aagcccaaaa aaacagctgc gattgtttgt
     2941 agaatcatca ccatagtcaa tgggaatttt tcgcccgcaa aataagaaaa aactactggt
     3001 aatttttgtt ctttaaagcg attatacgtc catgccgcta ctaaaccgga aataattcca
     3061 ccaaaaatcc ccatattcac ttctgggtcc ataatttcta agcctttttt caaggtagca
     3121 atcgctaaaa aaccagtaag tgcaggtatt cctttgtcct tatttttgac aaaaccgatt
     3181 gcaactccta tagcaaataa gatatccaag tttccaaaaa cggcatttcc agctgcacca
     3241 attactggga tgttcagcat atcgtcagct gataaacgca tgatcaatcc cgctaatggc
     3301 atcgctgcaa ctggaagtag catcgctctt ccaagcttct gcacatttga tttaacattc
     3361 atttttattc ctcctctatt aaatatcctc atatgttact aactcaatca aaggatcatt
     3421 tttcactttt tgagcaaatg ctgaatgaat taaaaattcg acttggtggg tacgaggata
     3481 cacaaaactt gaaccattta acaattcctg atccaaatac gctgcgtgac acatgacttc
     3541 gatcgtttta tcttctctca atatcatgag taaacttgcc aaatattctt ccacactcgt
     3601 attgatttgt cgtttttttt catcagtttc tcctacgaca tcgaaacaag gctcaaaata
     3661 atcgacatga cgaacttcat cttttcgttc aaagttgctc cgaaccggca aatcatattt
     3721 ttttgctaat gtaacaacta cctcctgatt ttcatccaaa gtatgagtat gatgatgact
     3781 gtctaaatga gttggtatga tccccgcatg ataaattttt tgaatctgag cattccattc
     3841 ctgatacagt tgatctttgt caatgttaaa tggatgctga taataagata aggatctgaa
     3901 ctctccgctt tcgataagag tatcgacagt tttgaggagt ggtttgccac acgtcaatgt
     3961 taaatggact cctacaccta gcctaggcat ttcctttctt agtttcacag catgctcgaa
     4021 acccggcata tttgccatca atgtagttga tgtcaaaatt cctcgctgat aagcatccat
     4081 aatcccataa ttcacaccat ggctatagcc aaaatcatcc gaattaaaaa tcacttttcc
     4141 catttcattc tccttctttt ttctactaaa ataggcgcaa ccaaataatc atagtccatt
     4201 tactatgtgt catttggttg cgcctataga tagttacgcc cttattttaa tagattcttg
     4261 ctagatgaat tgccaaatag atgatttcat tttcttgaat ggcaagttga aattgctgtt
     4321 cgatgatatc tttaatcttt agtgctgtac aatacgcttt gctatgttta aatgtttcag
     4381 taaaaaaacc aatattttct actggcgttt cttcctgata aatcaagcgt ttaaccagga
     4441 atttgatatg aaccattaag cgatgataag tcagtgattc tttatcataa acgtttgaat
     4501 aggatttttc tagatgggac aaaatcgtgg tcgtcatttc tactattttt aagctcttta
     4561 aactattagg ctctcctagc tcagcattaa tgatatgcat agtgatgaat cctacttcat
     4621 ttgaccctaa ctcggtttga tatcgatgat tgattcgctc gaccacttct actgctatat
     4681 catattcatt tggataaagg aatctcattt ctggcaacat aattgctgtg acatctctat
     4741 cttctctttt tcgttgaata gcaaaataaa tatgatctgt caatgtaata tagatatttg
     4801 aatctaatgg agaggagatc ctagctgtta tcagttcaat cacttcttcc gcaaaatcca
     4861 taaattcgat tggaatctgc gagactatct cactgaatcg tttgatcttt tctttagaat
     4921 ctaatacaaa taatttgtca gcatcctcaa catcaaatgg cttactcact ttagcagaaa
     4981 agccaatccc tttccccatc gcaatttttt ctattccatc gtcatcgatc aatacagcat
     5041 tatgattcag ctttttcatc acatacaccg ttaattcacc tcctctatat gataaaacaa
     5101 aacaacttgc agactccttc atacatattt ttgtctccaa acaattttta aagacaaaaa
     5161 acgacctaag aaagaaccct ttcttaggtc gtgcctaatt gaatagtagc accctacata
     5221 atttacaaaa atagtttaac acataataaa agcgttatca atatcttttt tactcgtttt
     5281 atgataatac ttgtatcgaa ttgatttgga ggtaattaca taaaaacaaa aaaaatatag
     5341 caactctcta taagaaagtt gctatattga taattatacc ggcggccggg gtcgaaccgg
     5401 cacgtcctca acggacactg gattttgagt ccagcgcgtc tgccaattcc gccacgccgg
     5461 caaatttaaa aataataact ggggtagctg gattcgaacc aacgcatgag ggagtcaaag
     5521 tcccttgcct taccgcttgg ctatacccca agaataaagg gcgaatgatg ggaatcgaac
     5581 ccacgaatgc cggagccaca atccggtgcg ttaaccactt cgccacattc gccatcataa
     5641 aagatgttat ttaatttctc aataaaaaac taagatgaag acatcttagt caataccggc
     5701 ggccggggtc gaaccggcac gccctcaacg ggcactggat tttgagtcca gcgcgtctgc
     5761 caattccgcc acgccggcaa gttgatttat tagtactaag gcggtaaccg gatttgaacc
     5821 ggtgatgaag gttttgcaga cctctgcctt accacttggc tataccgcca ttatactatt
     5881 atcaatctat aaaataaaga ataaattata g
//
LOCUS       DAFLWQ010000127         5770 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.131, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000127 DAFLWQ010000000
VERSION     DAFLWQ010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5770
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.131"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(1015..1305)
                     /locus_tag="L1V16_002784"
     CDS             complement(1015..1305)
                     /locus_tag="L1V16_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277057.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1707..1943
                     /locus_tag="L1V16_002785"
     CDS             1707..1943
                     /locus_tag="L1V16_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277058.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1950..3902
                     /locus_tag="L1V16_002786"
     CDS             1950..3902
                     /locus_tag="L1V16_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBN1277059.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3974..4471)
                     /gene="dfrG"
                     /locus_tag="L1V16_002787"
     CDS             complement(3974..4471)
                     /gene="dfrG"
                     /locus_tag="L1V16_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBN1277060.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(4798..5490)
                     /locus_tag="L1V16_002788"
     CDS             complement(4798..5490)
                     /locus_tag="L1V16_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBN1277061.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT         1894 a          997 c          917 g         1962 t
ORIGIN      
        1 catacttgca aagtaatact acaattccta acataatcgt agaatttaat aatttccata
       61 gcataaagtg tttagaaaag aacattaaga atagttctat aataattctt gaactccatg
      121 tcttataatg ttctatcgaa gcacccaaat agccaagttc atctaatcta cttgcataaa
      181 ctacgtcatc cgctctcata gtcggcatat acatattaaa gagtaaaaag ataccccaaa
      241 tccctattag taacaagatc agttctttgt tattcgttat ttttctatta tgtttgttca
      301 tttttatact ccttcttata tttcctaata gagtataaca tagctttaag cattacttaa
      361 agataactta aaagttatct tttaaatact taattgttaa ataccttatt tgatgcaaaa
      421 gaaatctacg atagtcaaca aaaaaatttt cattatatcc agaaaaattt ttcttagtta
      481 aggacctatg gattgcagta atgcagaatt cgtcgaataa actgccaaag acatacaatc
      541 atattgcttt taaaattgac gaacaagata tagattcgtt tgtctcaaaa atccaaatgt
      601 taggtttaac tgtcgaacca ggacgttctc gtgtgaaagg cgaggcttct tcaatttact
      661 tttacgacta tgataatcac ctcttcgagt tacataccgg tactctccag gaacgtttaa
      721 aatcctacaa ttccactacc tgagactagt aatgactagt ctctttttat ggcctctgat
      781 ccccccattg agcgaatact aatagggctt cgaattgatc tgttcaatct ttaagcaata
      841 tccctcaaat gagtttggaa agtttagtga ttcatcacaa atacttaaat acatgtagtt
      901 atatatagat tgaggttctt gtgagcgtat gctcgtgtgg gttcaaatcc catcgtctgc
      961 atccatcttt ccaaaacaag cggctaggac atttttgtct cagccgcttg ttttctagtt
     1021 tattctttca tcttgtcgga ccttttttct tgggtataga cttttctcat attctaccac
     1081 aattttgggt ttccctaaca catgatagga tctcacaaca aattgctttc tattattata
     1141 ataacctgta acgactaact tcatcccttc gtctacttca gctaggaagt tcaaactatg
     1201 ggaagcaatc aaacaattga ccccatttaa actgaaacgg atcaacggtc tggcactaac
     1261 ttgcaaagta cggatcttat ctactgttcc atattttttc tccataacct tcacctcaat
     1321 accattatac gaacatacat tccctttgta aagaagaaac tctgttttat ctttttgact
     1381 ttttgtctat tacctttctt aaaatcatat tggcacttcc tgcgaagatg aaggacatgt
     1441 actaaaaaaa agaggcagca gtatagattt aagtagttca gttttggagt acaaaaagtg
     1501 aaaatgtaaa cctaaatgag tatcaaattg caactgaatt tgatactcgt tttttattgt
     1561 taaatcaacg tttgttgtta atttacacca caaaatgtaa gttaaaatgt atataaaaat
     1621 gcgaacgtga aataattatt gtaggaatgc aaattggtgt gttaaaatgg ttacaattta
     1681 ctaagcaaaa aggggtgcat tttcctatgc aatttcttga gccaaaaaat aagaacgcta
     1741 agtctgtgga ttgggaaata tcagagcaag taagggtgat agttaagcaa tacgctgaat
     1801 atgcagagcg tactgaaagc gaagcagtgg atgaattctt attgaacatt ttagacgata
     1861 agaagtttat tgaatggatt gccaacaagc gaagtaataa gcggattgtt gaaaaaatgg
     1921 gtatcaaaga tagagtgggt tgatagacaa tgaccaagct taaaagatta gccacgaagg
     1981 aagatgaaat tgtagatgtt aaaattccga tttcaaacga agaattaaaa gatagggcta
     2041 aacaatatga tttattaact ccaaaacgat ttgcaacaag gtataacaaa atgttgttct
     2101 tgccaacgtc ttttaaatgg aacggttctg aatatcccat tcaatataat tactgcatca
     2161 atccgttttg ttgtaatttt gggaaagaac agcacaaatt caaagatgta aaagggaaac
     2221 caagtcgata taaaatgact ggtagttcca aagataaagg tcataaaggt atgtactgca
     2281 atgacaatcc tattggcaga ggtgtatcgc aaaactgtac agtaacccct ttatctaatt
     2341 ggtctgttgt tgaagaaatt aaacgcctta tagaaatcaa tagcatccaa gatgttgagc
     2401 cagattatca atttcataaa gaaggctgct cggaagaaga atcaacccca ttcaatgagc
     2461 cgaagcaatt ttacaaaagg gggaaaagta ggggcaaatc tcaacgctat caatgtaagg
     2521 cgtgtaagaa gttcactaat gttctaccaa aaagagaaga aaccactact tatcaccaac
     2581 aaaagaacac cattcttcca atgttcgcta agatggttgt tggaagggtt tcagtcagtc
     2641 gtacttgtga tattttagga attggagttg gaacctacta tcataagctg gagtggctgt
     2701 ataggcgttg tttggagttt ttagaacgat atgagacaca accccttcaa acaaagaaat
     2761 ttaacgagat gtggcttaat acggacaaga tgcactacta cctaaataac gtccgtaaga
     2821 aaggacaagg ttcaaagaaa tatacggggt ttgaagacct taatatgcaa acgtatatag
     2881 ttgtatctgc tgaggtctta tcaagatatg tgttccgttc tgatgttgcc tatgattgga
     2941 atatttcaat ggatgaatta aatgaagata caagaaaatt caaagaagac catctcaata
     3001 cttttagtcg taaaaatgat aggttagatt ggtcttatta tccacaagaa ccatccgcta
     3061 acgatagcga aaataggaat gcttatcttc acgaattagg gaaaattact aataggagta
     3121 gatttgtcga tggtttaaat gttgatgctc cttatactac aactgctcac tattggttaa
     3181 ttaaacaaat ggttaatgcc gacgaatggc gaatgattag tgatgatgac ttctctatta
     3241 gaaacgcctt ttatagagta ttcacgaaag aattaaggtt gagcgatgca catcatttta
     3301 tttgccaagt taacaagacg aaaagcagaa aacaatgctt aaaagaattc ggacaagcaa
     3361 aagcagaact gctcgattgg ggagatatca gaggattcaa aacaaagttt ctacggactt
     3421 tggcatctca ttatctaact gaattactaa caagtcatca attccacgaa gaggctatta
     3481 gtaaagatgg agaaagatat cgcaaatatg ccgataaccc tatcaaacat ccattagcca
     3541 ctaaggataa aggattttat tcagttgatt gtagaacgga tttatctgct ctggaaccaa
     3601 acgaaatcgc aaagatgcta ttaaatgtta atgaccattc gaccaatagc tttattcaac
     3661 agataagacg ttatatatca tctcttgaaa gaccattaac aacagctcgt ggtgataaga
     3721 agagctatat ttacgctaac ttcaatccga agtatgctca atttgcgatt acaattctaa
     3781 gaacttacta caacttttgt cgccctttta aatcagcgga taaaaaggtt ttgacacctg
     3841 ctcaaagatt agggattaca gataaacaat ttgattggaa agatataatt tatttcaaat
     3901 gacaaaaaga gcttggagta atcccaagct cttgtgcttt atctttactg ttcttcttca
     3961 attaacgcac ccgttaactc aataagtttt ttctttcata tacatgaaaa tagtagttat
     4021 acggattttt atcattcttt atcccttttt gggcaaatac ctcattccat tcctcataat
     4081 tcacttctgg aaaaaaagta tctccttcga attcatgatg tatttttgtg atgtacattt
     4141 tctcaacata agggaaaaac aaattataaa tctgttctcc tccgaaaata aaaatttctt
     4201 cttcgttttt acataactca aaaacatctt ctattgaatg aacaatttca caaccattaa
     4261 aggtaaaccc cttatctctc gtcagaataa tatttcttct gtcaggtaag gctcttccga
     4321 ttgattcaag gttcttccta cctaatatta tcggatgtcc ctttgtagta tttttaacat
     4381 attcccagtc cttgggaatc ctccaaggaa tgtcattctc tttgccaatc actctattct
     4441 tatccatcgc agcaatcaaa gaaactttca tttataacac agccttttta actaatttac
     4501 catctaattt cttatttcta tcaaaaaacc ttttctcatt atcctgcccg ttagttgaat
     4561 aagcaatttt ttctataagt tatattatca taataccaca aaatcacaaa ttttcattca
     4621 attatcattt tcaattgcat tttataaatc attttgtatg taatttggta tgtaagttaa
     4681 aatgaaaaaa gtagtccatt ttgaagtaca ttttgtcatt ttgtactcca aaactgaact
     4741 acttagtata gattactgtt gcttctttac taatttaggt ttacttgtta agaaagatta
     4801 tttacgcaaa tgttcttcaa caatttgctg agatttatca gctgtatctt ccacttcatc
     4861 ttttgctttt tctaactttt gaatatattg tttcaagctt gagttttcag cagttgcttc
     4921 gtctaatttc ttttgtgtat ctgttaactg agtttctaca tttgtttttt cttgtgtcag
     4981 tgttgcgatt tgttgattca aaccatttac agtattttgt aattctgaaa gttttgcttg
     5041 tgcttcttgt agtcttgctg tccaatctgc attcagatga ttgatttcat catttttttg
     5101 gttgatctca tctagtttga cattgatttc attttgtttg ctttgtagtt gtgcatcctt
     5161 gctgactaat tgactttcta agttttgttt ttctgctgcc gattgatttt tttggttttc
     5221 taattcattt acttttgttt ggtattcttg gacatctgcc tttgaatctt gcaatgtctg
     5281 ttctttttgt gctagtcgag cggtaagatc tgtaatcgct tgctctttat ctgtcaatgt
     5341 atgatcaagc tgtgtcagat tctcattgat tgtatcaata tctgtctctc caccccacaa
     5401 aataatttca tttgcgtacc gcgtgcctgt gtagccaatt agacatagaa atgcaacgac
     5461 aatcccacca gtaataaatt tctttttcat ttgcatagct ccttaatcca atacttttac
     5521 atgctaaaag taagtgatct caaacacaat gtcaagcgtt tttaaattac atatgtaatt
     5581 ttaatataaa tactatcaaa tactcattta atcctccttt tttatctatt taaaaaatct
     5641 tttttataga gaaaaatgca ggttaatact ttcttaaata aatatttatg gtgaacaaaa
     5701 acaaaaaagc aagttttatt aaacgtaacc cttttcattt catagattac tgtatttatt
     5761 acaaaaaacg
//
LOCUS       DAFLWQ010000128         5585 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.132, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000128 DAFLWQ010000000
VERSION     DAFLWQ010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5585
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.132"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(488..1297)
                     /locus_tag="L1V16_002789"
     CDS             complement(488..1297)
                     /locus_tag="L1V16_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1277062.1"
                     /translation="MVKESVIGKKELRSIFWRSFFMQSSWSFDKMMAYGQMNGIERSL
                     RKIYPNDDDYYTALQRHTETFNITPHIAPFVMSLSVTMEEENAKNPEFDTDAINKIKT
                     GLMGPLSGIGDSFFWGTFRVIAAGIGISFAQQGNILGMILYFTLYTAIHFIFKWLATK
                     YGYVLGTKFIDDTEDNHMIDKLSHGASILGLTVIGAMIGTMVTLNTSLKFTVGGAETS
                     LQSIFDQIFPGLLPLGITFLCVWLYSKGHKTITIILGIFVLCFLGTLGGIF"
     gene            complement(1297..2043)
                     /locus_tag="L1V16_002790"
     CDS             complement(1297..2043)
                     /locus_tag="L1V16_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1277063.1"
                     /translation="MIQAILIALVAFLASIDEYTFGASMMGRPLFTAPFVGLILGDLE
                     SGIIIGATLESMFMGSIMVGSATPPEVYASSVLGTAIAIQSGQGVGTAVALTLPLSIF
                     LQMWRNFAYAMPITYFNNKMDEALVNHDFKKAQKYHYVAQPLIVGVPSAILVFVATYF
                     GVSTINAMIKLIPQVVLDSFDVAAGVLSCVGLALLIKMMANKAMMPYLFLGFVGVMYL
                     KMDVVGVAVVGLCLALLAVQKLTFEEEEDL"
     gene            complement(2061..2528)
                     /locus_tag="L1V16_002791"
     CDS             complement(2061..2528)
                     /locus_tag="L1V16_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1277064.1"
                     /translation="MIKLLRVDERFVHGQVAFAWTNNLGANCIFVASNEIATNNLRKK
                     TLKMAVPTGTKFVVKDMTEAISVLNGEKIKKYQVFLIVGTVEDAYEITQHVPEIKEVN
                     LGNLKKNENRKMITSSVYLNEQELDLVKKMTENGITVQCQAVPTDKKINPLHD"
     gene            complement(2528..2938)
                     /locus_tag="L1V16_002792"
     CDS             complement(2528..2938)
                     /locus_tag="L1V16_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBN1277065.1"
                     /translation="MRKIVIATHSMMAKGLKDTLEFIIGPQKSLLAITAYIDSDYSIN
                     QEIEQLFSDLAPDDELIVTVDLLGGSVSNAFSEQIGKDNFYLISGVNLPLLLELCLSG
                     EQDTKKLIQKAMNSGNEGIVLVNELLEKTEEDDF"
     gene            complement(2949..3962)
                     /locus_tag="L1V16_002793"
     CDS             complement(2949..3962)
                     /locus_tag="L1V16_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1277066.1"
                     /translation="MLGFSEERFLSVLNGAVKNIETINQVADAISEKGFKNLYLVGSG
                     GTYATISPLAYLLSTHSELDYYHEIAAEVVCSQPKKINKDTVLITSSLTGTTQETVDV
                     VKYANSQGATTIAFVGNAATPLGEIVDYAIENDADNDTLVEELQLQFFALGARLMKNN
                     GEFPEYDEFIQTLQKMPEVLLSVRQQNDQKALEFAEKHKNTEFHMFVGAGNTYGAAYE
                     YAMCVLEEMQWIATKSIHAAEFFHGTIEMTDKSMSFVLLKGEDQTRPLVDRVERFVNK
                     YSDVVTVFDTADFELAGVPSAMRQYVAPMVMATALERVSAHFEKVRDHSLDIRRYYRT
                     VEY"
     gene            4179..4913
                     /locus_tag="L1V16_002794"
     CDS             4179..4913
                     /locus_tag="L1V16_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1277067.1"
                     /translation="MNTEELTNKLIQDIEQEKYKYAQAIPSERDFVQIYEMNRSAVKK
                     AIQQLVNKEYLLKIHGKGTFVKKNIHEHLQIKFHGLSELLEREGIQPSSLILASEIKP
                     AGHIVGKALQLEPTEEVFHLVRLRSGDGEPISIEDTYIPLNLIPDLQAFDFQIFSFYS
                     TLAAYHYQIENIYQTISSSKVSNKEARLLKTSLNRPVISLAITAVTTNEQAVEYTEVV
                     VLPEFAAIYTKNVHQGKEMKIYAQID"
     gene            4897..>5585
                     /locus_tag="L1V16_002795"
     CDS             4897..>5585
                     /locus_tag="L1V16_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1277068.1"
                     /translation="MPKLINLLAYDLIDKIIAYIHEHHLTPGTKLPSERDLSEMFNVN
                     RTTLRGALQKLVDNGTLRAQTNSGYYLTAPKFEKNAHHFFTPIEDSLLSKQRLQLKAT
                     ALSPKKAAALCPELNDFKQQQPQAYLEYIDAEAISLMLLIPMETLKKSNFSDNPFQDF
                     KSLAYTRSQEISLITDNDVAADLLGVDKEEVLLFVREEIRAGKELAAIALGYTISRRC
                     NIQVNVATTLQS"
BASE COUNT         1790 a         1184 c          920 g         1691 t
ORIGIN      
        1 aagcgacaaa aaccacgagc aggtccattc atcctcaaac ctcggtgatc ttcgcggttt
       61 aacaccatca gaagaaatgc acaaaaataa taaggagagt ctgagacata aataaattcc
      121 cagactttta gtgagtctaa atccgaataa acggtgggtc gaaagcaact ctagctgcgc
      181 gtcgatcgca gcaatctcta ggtgctatgt tcggataaat ggtggtcaaa agtcagattt
      241 tcggccattt cgtaacagcc aaccagacaa aaagcgtctg ttttgtcttc tactccaatt
      301 gctcaaatct tagcgacttt tggcttggtc ttactctaaa cagtttgtaa gcctaaactt
      361 tatttgctgt ttgtttctaa gatcaaagca aaactacttt ttagttggtt acttttacaa
      421 gttcttttta ctgttgaata aatgtaaatc ttaagaacaa atatttactt ctataattcc
      481 aagtttctta aaaaattccg ccaagtgtac ctaaaaagca taaaacaaaa attcctagaa
      541 taattgtgat cgttttatgc cctttggagt aaagccagac gcataaaaag gtaattccta
      601 atggcagcaa gcccggaaaa atttgatcaa aaatactttg taatgaagtt tcagctccac
      661 caaccgtgaa ttttagtgac gtatttaaag taaccatcgt gcctatcatc gcgccaatta
      721 ccgttaaacc taaaatcgaa gcaccatgag ataatttgtc aatcatatgg ttgtcttctg
      781 tatcatcaat aaatttagtt cctaaaacat agccatattt tgtcgccaac catttaaaaa
      841 taaaatgaat ggcagtatac aaagtaaaat aaaggatcat gcctaaaata ttcccttgtt
      901 gagcaaaaga aatacctatg ccagccgcaa taacccgaaa agttccccag aaaaatgaat
      961 cgccaatacc tgataaaggt cccattaatc ctgttttgat tttattaatt gcgtctgtat
     1021 caaattcagg atttttagca ttttcttctt ccatggtgac ggacaagctc ataacaaaag
     1081 gcgcaatatg cggtgtaatg ttaaatgttt ccgtatggcg ctgcaacgct gtataataat
     1141 catcatcgtt cggatatatt ttacgtaagg aacgttcaat accattcatt tgtccatatg
     1201 ccatcatttt atcgaaggac caagaggatt gcataaaaaa ggagcgccaa aatatacttc
     1261 ttaattcttt tttcccaata acactttctt ttaccattat aaatcttcct cctcttcaaa
     1321 agttagcttt tgaacagcca gtaacgctaa gcaaagtccg acgacagcca caccgacaac
     1381 atccattttc agatacatta cgccgacaaa tcctaagaaa agataaggca tcatcgcttt
     1441 attcgccatc attttaatta ataacgctag cccaacacaa gaaagcacac cggccgcaac
     1501 atcaaagctg tccaatacaa cctgaggaat caacttgatc atcgcattga ttgtagacac
     1561 accaaaataa gtagctacaa aaactaaaat ggccgatgga accccaacga ttaaaggttg
     1621 agccacataa tgatattttt gtgctttttt gaaatcatga ttgactaatg cctcatccat
     1681 tttgttgtta aaatacgtaa ttggcattgc ataggcgaag ttacgccaca tctgaagaaa
     1741 gatggacaaa ggtaaagtca acgcaacggc agttcctact ccttgacccg attgaatcgc
     1801 aattgctgta cctaaaacac tggaagcata aacttcaggg ggcgtcgcac tccctaccat
     1861 aattgagccc atgaacatgg attccaaggt ggcaccaata ataattcctg actctaaatc
     1921 tcccaaaatc aaaccgacaa aaggcgctgt aaatagcggt ctacccatca tcgatgcacc
     1981 aaatgtgtat tcatcaatag acgccaaaaa agctaccagt gcgattaata ttgcttgtat
     2041 catattcttc ccctcctctt ttagtcatgc aaaggattga tttttttgtc cgttggtaca
     2101 gcctgacatt gaactgttat cccgttttca gtcatttttt tcaccaagtc cagttcttgt
     2161 tcattcaagt aaacggaact agtaatcatt ttccgattct cgtttttctt taaatttcct
     2221 aaattcactt ctttaatctc aggtacgtgc tgagtaattt cgtaggcatc ctccaccgtc
     2281 ccgacaatta aaaatacttg gtatttcttg attttttctc catttaaaac agagatggcc
     2341 tctgtcatat ccttcaccac aaattttgtc cctgtaggaa cagccatttt tagtgttttt
     2401 ttgcgcagat tattggtagc gatttcatta cttgcaacga aaatacaatt tgcacctaag
     2461 ttatttgtcc aggcaaaagc aacttgccca tgaacaaaac gttcatctac tcgtaataat
     2521 ttaatcatta aaaatcatcc tcttctgttt tctctagcaa ctcgttcacc aaaactatcc
     2581 cttcattccc gctattcata gctttttgga ttagtttttt cgtgtcctgt tcacctgata
     2641 agcaaagctc taaaagcagc ggcagattta caccgctgat taaataaaaa ttgtctttac
     2701 cgatttgttc ggagaaagcg ttagacacgc ttcctcccag taaatctacc gtcacaatta
     2761 attcgtcatc aggcgctaag tcggaaaata gctgctctat ttcctggtta atggagtagt
     2821 cactatctat atacgcagtt attgctaaaa gtgatttttg aggaccaata ataaattcta
     2881 aagtatcctt taagccttta gccatcatgg aatgcgtcgc aattacaatt ttcctcatag
     2941 ctcttacctt aatattccac agtccgataa taacgacgaa tatctagtga atgatcccgc
     3001 accttttcaa aatgagcact cactcgttct aaggccgttg ccataaccat tggcgctaca
     3061 tactgacgca tagcgcttgg tacacctgct aattcgaaat ccgcagtgtc aaaaaccgtc
     3121 acaacatcgc tatatttatt tacaaaacgc tctacgcgat cgactagcgg acgcgtttga
     3181 tcttcacctt ttaataacac aaaactcata gatttatcag tcatttcaat agtcccatgg
     3241 aaaaattcgg ctgcatggat cgacttggtg gcaatccatt gcatttcttc cagtacgcac
     3301 atagcatatt cataggcagc cccataagta ttcccggctc caacaaacat atgaaattcc
     3361 gtatttttat gtttttctgc aaattcaagt gctttctgat cattttgttg ccgaacactt
     3421 agtaatactt ccggcatttt ttgtaatgtt tgaataaatt catcatattc aggaaactca
     3481 ccgttatttt tcatcaggcg tgcacccaaa gcaaaaaact gtaactgaag ttcttctact
     3541 aatgtatcgt tgtcagcatc attttcaatc gcataatcca cgatttcccc gagtggtgta
     3601 gcagcatttc ctacaaacgc aatcgtcgtt gcaccttgac tattggcata cttaacaaca
     3661 tcaacggttt cttgagtcgt accggttaat gaagatgtga ttaacactgt atctttatta
     3721 atctttttcg gctgtgaaca aaccacctct gcggctattt catgataata atcaagctct
     3781 gaatgagtgc ttaacagata agctagcggg ctgattgtgg catatgttcc accagagcct
     3841 accaaataaa gatttttaaa tcccttctca ctgattgcat ctgccacctg attgattgtc
     3901 tcgatatttt ttactgcacc atttaatact gatagaaaac gttcttcgct aaaacctaac
     3961 atagttaaaa acctccaagt caataatttg aaaaatatat ttgcaaatgc cggcacatta
     4021 acaaaccact taaccttttt tatataccac ctgttaacgt ttttaatgta ccacttatag
     4081 aaaacgctgt caatagtttt taaccacttt tatttttatt tgtaccaaaa tccttttttc
     4141 atgtataata aacaaaaata gactctggag tgtaacgtat gaatactgaa gaactaacga
     4201 acaaattaat acaagacatt gaacaagaaa aatataaata cgcgcaagct attccttcag
     4261 aacgtgattt tgttcaaatt tatgaaatga atcgttcagc cgtaaaaaaa gccattcaac
     4321 aattagtaaa taaagagtac ctactaaaaa tacatggcaa aggaactttt gttaaaaaaa
     4381 atatccatga acatttgcaa atcaaatttc atggtttgtc tgaattgttg gaacgggaag
     4441 ggattcagcc tagcagctta attttagctt cagaaataaa accggctgga cacattgtcg
     4501 ggaaagcttt acagctggaa ccaactgaag aagtatttca tttggttcgt ttaagaagcg
     4561 gcgacggtga gccaatttct attgaagaca cttatattcc attaaatctc atacctgatc
     4621 ttcaagcttt tgatttccaa attttttcat tttattccac attggctgct tatcattatc
     4681 aaattgaaaa tatctatcag acaatttcca gctcaaaagt gagcaataaa gaagcccgtt
     4741 tgttaaaaac cagcttaaat cgtccggtaa tcagccttgc tatcactgcg gttacgacaa
     4801 atgaacaagc ggttgaatac actgaagtag tggttttgcc tgaattcgcc gccatctata
     4861 ctaaaaatgt tcatcaagga aaggagatga aaatctatgc ccaaattgat taatctgttg
     4921 gcttatgacc tgattgacaa aattattgct tatattcatg aacatcattt aacccccgga
     4981 acaaaactgc cttcggaacg ggacctatca gaaatgttta atgttaatcg aactacctta
     5041 agaggcgcgt tacaaaaact ggtggacaac ggcaccttac gggcgcaaac caatagcggc
     5101 tattatttaa ctgcgccaaa attcgaaaaa aatgcccatc atttctttac accgatagaa
     5161 gattctctgc ttagtaagca gcggctacag ctaaaggcaa cggctctttc accgaaaaaa
     5221 gcagcagctc tttgtccgga actgaatgat ttcaaacagc agcaaccaca agcttattta
     5281 gaatatattg atgcagaagc aattagcttg atgttattaa tccctatgga aacattaaag
     5341 aaaagtaatt tctcggacaa tcctttccaa gattttaaaa gtttggcata tacgcgttct
     5401 caagaaattt ctttaataac tgacaatgac gttgcggcgg acttgctggg agttgacaaa
     5461 gaagaggttc tgttatttgt acgagaggaa ataagagccg gtaaggagtt ggcggcgatt
     5521 gctttaggtt atactattag tcgccgctgc aacatacagg ttaatgttgc tacgaccttg
     5581 caatc
//
LOCUS       DAFLWQ010000129         5493 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.133, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000129 DAFLWQ010000000
VERSION     DAFLWQ010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.133"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(55..421)
                     /gene="ssrA"
                     /locus_tag="L1V16_002796"
     tmRNA           complement(55..421)
                     /gene="ssrA"
                     /locus_tag="L1V16_002796"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(592..1365)
                     /locus_tag="L1V16_002797"
     CDS             complement(592..1365)
                     /locus_tag="L1V16_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1277069.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            1509..1859
                     /locus_tag="L1V16_002798"
     CDS             1509..1859
                     /locus_tag="L1V16_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBN1277070.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            1840..2556
                     /locus_tag="L1V16_002799"
     CDS             1840..2556
                     /locus_tag="L1V16_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1277071.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            2556..4004
                     /locus_tag="L1V16_002800"
     CDS             2556..4004
                     /locus_tag="L1V16_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1277072.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4074..4583)
                     /locus_tag="L1V16_002801"
     CDS             complement(4074..4583)
                     /locus_tag="L1V16_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277073.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(4573..5298)
                     /locus_tag="L1V16_002802"
     CDS             complement(4573..5298)
                     /locus_tag="L1V16_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277074.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         1863 a          958 c         1095 g         1577 t
ORIGIN      
        1 aaacgttgat ttaacaacgt ttttcataca tgtttatctg tctcaaccat acatatatgg
       61 agacggcggg agtcgaaccc gcgtccaaac acatcgccac ttaaaaatct acgttcatag
      121 tcaactcatt taaggattca ctttacagct tgccgagtga caggcattct gtatcgctag
      181 tctgatgttc tctttttcaa cttacagacg gaaagttgaa acgtatccca ctaaagttag
      241 gacccttact cgagcacatg ggcgatgccg agaggatcta cgctaactgt ttttaggcag
      301 ctaaagcgta agagttgttt tcgtttttag cagttatatt taactgtaac gtttttacgt
      361 agacgtaacc tacgaaacgc aattcaagct cgactgtgcc tgtcgaatcc gtaacgtccc
      421 cgttagctaa caagggttac gtgtattttt catacaaaat tagtatagca tatattggga
      481 taaattcaat aaaaaagcga atcatatccc attatttata taataactgc ccctttctta
      541 agaaaaaata agcgattttc ttaagaaaag aggtagcttc aaaaaaagat cttaaatcag
      601 atcaaaatac ttcaatgcgt ggacaattcc gccttctgta tttttctttg tgataaaggt
      661 agaaagttct tttaatccgt cataggcgtt gtccatagcg attttgttgt cgcaagcttc
      721 caacaaggca aaatcattcg gaccatcgcc aaatccaaaa gtaggaactt tttccagctg
      781 aagttctttt tgcagacgtt tgacacctgc cccttttgag attcctttct tcactgtatc
      841 gatcgagtaa ggaccattcc gataaaaagt tagctcagga aaatgttcgt gatagtattc
      901 gtcacctgat tgagataaga tcagcaacat atttactgtg ttttctttaa agcctaaagg
      961 atcaatttcc ggaacatctg aatgaatgaa gtcgtaagca ttgatcattg tttggctatg
     1021 accggtacac cagattttct gatcgttata gtaagaaagt tcatgaccgt tcaactgtac
     1081 atgatcatac attttttgac attcttctga agaaaatgtt tgagaataga tttcttcgcc
     1141 gtctactcga atgaaagaac cattcatggt gaccgcagaa gtaatgcccg catcttccat
     1201 gatagagtgg atttctgctt ctgtacgtcc tgtagcgatg acggggagaa cattgttttc
     1261 ttttaatgcg ttcatagctt ttgccacttc gggtgtgatt tttgatttcg catctagtaa
     1321 tgttccatca agatcaaaga aagtgattgc acgataattt gacacaaata aaactccttt
     1381 tttattggaa taagtttatc ttaacaaaga atgaacaaaa gacaaacctt tcgtgaagaa
     1441 ttcctgaaca tattggttca gtcaacaatt tagagtatac tataagaaga gaatttagga
     1501 gggaaagaat gatttttttc agtattggta tcttattctt aataattggc agtctttttc
     1561 ggattctgcc ctcaaaagga aatctgcctt tttatgggta tcattcgcct cttgccgcaa
     1621 aaacagacgc tcattggcgg ctggctcaaa agacaagcgg aaactggttt tttcttatgg
     1681 gcttactgat ggcattgatc ggctattatt taaagacatc tgggcatacg aattattttc
     1741 tgattgaaat gcttctgcta gtatttccaa ttatgcctat ttttattatg acagaaaaga
     1801 aattacagaa atatgacctg gaaactggag ggaacgataa tgaatatttt aatgattgaa
     1861 gataatcaat ctgtttctga aatgatgcag atgtttttct taaatgaagg ttgggaagca
     1921 actttcaagt atgatggaaa agaagggctc gatgcctttt tagaaaaccc acaacattgg
     1981 gatatgatta cactagacct gaatttgccc acactggacg gtatgctagt aggaagagag
     2041 atccgcaaag tttcaagtac tgtgccgatt atcatgctga cagctagaga ttctgaaagc
     2101 gatcaggtga tcggcttaga gatgggggca gatgattatg tcacaaaacc tttcagtcct
     2161 ctgacgctta ttgctcgaat gaaagctttg catcgccgta gtgagttggc agaagcaaga
     2221 gaagaagcag cagtttcaga tgatcatttt gatatcgaga ctagtcattt caagatgaat
     2281 acgaaaacac gagaagcgta tctggacaac cggccaattg aaggactgac gcctaaagag
     2341 ttcgatctat tgtttacttt agcaaaaaaa ccacgtcaag tattctctcg ggagcagttg
     2401 cttgaattag tctgggatta tcagtacttt ggtgatgaac ggacagtgga cgcccatatc
     2461 aagaaattac gacaaaaaat cgaaaaggtc ggaccacaag tcatccaaac tgtttgggga
     2521 gtcggctaca aattcgatga ttctggtgtt gcctaatgcg ttatttgtat cagcaactct
     2581 tagctttttg cggaatggtc gcgttgatct tattgatcgt tggagtttct tttacacaac
     2641 tgacaaaaca aacgattgaa gaaaacaatt accagcaact gtttggatat gctgaatcag
     2701 ttgaaaagac aacgcaaacc tatgccgata cgctcccgca gtttagtcaa gatcaggcgt
     2761 ttcaaaatgc attgctgctg acagagcaag tactgacaga acaaaatgtg aactttatat
     2821 ttatcgataa aaacgaacgt gtcatttatc cgactaatac agctttactg aattttacct
     2881 taacagctga tcaatggaaa aatctgagga atggacgtca agaaaaattc acatcgaata
     2941 aaaatatttt aggacaagca caggcgacct cttacgcact tgtgccattt aatttgaatc
     3001 atgaattcta tggagcactt gtagttagtc aacctgcgcg aaatatcgat aacagcgttc
     3061 gtccaattac actgaacctg ttcaaaggat ttattttttc cagtatcgtt gcagttattg
     3121 ccagctatgc ttttgcagca ttccaagtta agcgtatcaa tcggttaagg aatgcgacga
     3181 aagaagtgac gaatggtaat tttgatgtac agctccccgt acatgacaaa gatgaatttg
     3241 atgagttagc agatgatttc aataaaatga cgaattcatt gaaagaatct caagcagaaa
     3301 ttgaagaaca agaaaatcgt cgaagacaat ttatggcaga tgcttctcac gagatgagaa
     3361 cacctcttac gacaatcaac ggacttctgg aagggttaga atacaatgca atccctgaaa
     3421 atcagcgaga aaacgcgatt aaattgatga aaaatgaaac agagcgtctg atccgtttgg
     3481 tgaatgaaaa cttggattat gaaaaaatcc gtacgaatca aatcagtatg gtcattaaaa
     3541 aattcaatgg aacagaaaca ttgaaaaata ttgttgcaca gttagaagct aaagcagaag
     3601 cagcaggaga tacattgaca ttgaaagccg ttgatgatat tgatgtttac gctgattatg
     3661 accgatttgt ccaaatcatg gtcaatatta ttcaaaacgc gatacagttt actgaaaacg
     3721 gccaaatcac gattacttta gaaaaaggct atcttgaaac gatcatcacg attgaagata
     3781 cgggaattgg aatgtctgaa caacaaatga aaagtatctg ggatcgttat tataaagtag
     3841 atccttcaag aaaaaataca aaatatggtg aatcaggatt aggtttacca atcgtgcagc
     3901 aacttgtacg cttgcataaa ggaaaattag aagtagaaag cgaactagga aaaggaacaa
     3961 aattcgctgt tcgtttgcct gacgtagaaa tcaaaaaaga gtaaaaaaca agcggtataa
     4021 aagatcatga atcgatcttc tataccgctt gtttttacta taaaatgatt gatttagccc
     4081 gcgggctcta aacgatcaat ataaggactt tgagcaatag tagcatcatg agtaaagagt
     4141 aagatacctt gattttcttc atgagctaaa taagaaagca agtggagtag ctcttggatc
     4201 tccaatacac taagttcatc aaatgtatct tcaataacaa tattgtttcg cttggaaagc
     4261 aaggcatgaa gtaattgcag ctttactttt tcaaaagacg tcaactcagc tgccgcacaa
     4321 ttaagcaagg aaggagagat atcaagtttt tcttgatagg ccaaacgatc ttgtttgatt
     4381 tctttttccg gtacatccaa caggacatgg tctttaagat tcagataagg aaacatcggc
     4441 caattttttt ggatgatcgc aaaattatcc agttttgcaa caagaacctc ttttttcaag
     4501 tgctccaata ttttatgctg tttttcgaga ggacacaaaa taacggtcaa gtgttcagca
     4561 tgaatcaaat attcaggttt cattacgtcc aggcctccta ctttgcaaat gatggataaa
     4621 aaaagtgaaa gggaatagac taagaatgag acagcatcca ctgagcccaa taagagtttg
     4681 ggcaaatccc ttaagtatat ctgtgaaaaa aagatcattt tggaaatcga tggtaaaaaa
     4741 agtctgttga tccatcggaa ttgtaagtcc gcttaccgaa gtcaagatat cacggatatc
     4801 tggcagttca gtagtcttta agacaagaaa attgatcctt tgaagaagcg cttcataaac
     4861 tgactggaag ctgacgatcc acaataaaac caagatacaa caaagaaaga gaggaaagaa
     4921 cagctgccag aaaataaaaa ggaataattt ggttttagaa agaccagtca ggcgccaatt
     4981 gatcaattcc tgcttgtttt gcctgactga atagtaaaag aaaaagataa aaaggaaggc
     5041 aaatagaaaa aataaactga atatgccttt tatataaaat cggctagcta attctaaagc
     5101 cggaagaagc tctgtagatg cagaagcgcc aataaatgaa agccgatctt ggacttgatt
     5161 ggctaaagcc gattgcgaat ggtaaagagt caggcatgct atcaataaaa aagcagaaaa
     5221 gcttgaaaat aaacaataga gtattgtctg ctttttgtaa taaattaatc gagcagtagc
     5281 atagcggatt attttcatac ttttcacctc tataaaaagt atagaaaatg aatatgaata
     5341 aagtatgaaa ttcctttagt gaaatcacga attaaaacca gaaaatattt tgtaaaaagc
     5401 aagaggttgt gaagaagctg ccctattcta ttaccgtaga tgcaagcttt tgaacactgt
     5461 ttattcgaaa agaggagcag cgacaataat ttt
//
LOCUS       DAFLWQ010000130         5444 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.134, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000130 DAFLWQ010000000
VERSION     DAFLWQ010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.134"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..571)
                     /locus_tag="L1V16_002803"
     CDS             complement(<1..571)
                     /locus_tag="L1V16_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HBN1277075.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNG"
     gene            complement(905..992)
                     /locus_tag="L1V16_002804"
     tRNA            complement(905..992)
                     /locus_tag="L1V16_002804"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(958..960),aa:Ser,seq:cga)
     gene            complement(1137..1703)
                     /locus_tag="L1V16_002805"
     CDS             complement(1137..1703)
                     /locus_tag="L1V16_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1277076.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            1958..3289
                     /locus_tag="L1V16_002806"
     CDS             1958..3289
                     /locus_tag="L1V16_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HBN1277077.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            3255..3605
                     /locus_tag="L1V16_002807"
     CDS             3255..3605
                     /locus_tag="L1V16_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277078.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(3697..4116)
                     /locus_tag="L1V16_002808"
     CDS             complement(3697..4116)
                     /locus_tag="L1V16_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBN1277079.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(4117..4461)
                     /locus_tag="L1V16_002809"
     CDS             complement(4117..4461)
                     /locus_tag="L1V16_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBN1277080.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            4811..5407
                     /locus_tag="L1V16_002810"
     CDS             4811..5407
                     /locus_tag="L1V16_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBN1277081.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT         1513 a         1008 c          930 g         1993 t
ORIGIN      
        1 ttccatttga tagcgagcga taattgttca gattaaataa ttgataatca aatggcggat
       61 tatttgtcaa cacaccgaca ggattatcat ataaatgaag tccatctttc atactttcaa
      121 ttactatcga tttttcttta tcagctaata accagtgtaa aggtgacaag ggtagttttt
      181 cactaaaatc gatattgact agattgatag tagccaataa ttctttagct tcgtctatgg
      241 ttgagcattg ccctagtatc catggaataa actcaaatgg tgcaacgtta tcttttcctt
      301 cttgtaattc tttataatca gcattgccag gaaaattcag tcctgccata ctcaaccctt
      361 tttcatttgt agcctcataa tagagtggat agttggatac cccagctgct attcctatca
      421 ttgcataatg tttatctaaa ttttttacct ttctaaaatc gaaacgataa tttcttggag
      481 taatagtgac cacttcatta taagacatct cataatcaaa attccttcca aaataatggt
      541 ctttcgttgc ataagtgatt gcggtacaca tcgtttcccc tcctaaaaca aatcgttttt
      601 acacttttat cttacatcta gtattttttt tatcaaaaaa aggccaaaga agattgattt
      661 actagcattt ataaaaaata gtactcaggg ggaatcaaaa aatattgtag gttaaaagta
      721 caacaataag gggctgtgac aaaagtcttg tcacagcccc ttattccgaa caaacggtgt
      781 tcaaaagctt gcatctgcgg taataagccc aatcaaacga aaaaatagga aaagctattt
      841 ttgtttggcc gttcttatta cttgatgcag gacagcttct tcacaacctc taatcgttga
      901 tataaggaag gtacaggatt tgaacctgcg cgccggtatt agccggttcg ccggatttcg
      961 agtccggtgc attaccactc tgccaacctt ccgtaagtac tatttttaaa cttttttcac
     1021 gaaatgtcaa gcctatttct aatagataaa taacagaaat cgcttttttt agcaaaaaag
     1081 tccattgaca gtttgcagcc aacggactta ccgatcaaat tcatactgat agaacactat
     1141 ctgattattt caggattatc taatgctaaa atcgagtcaa ttgtccgttt gatcagtgca
     1201 atgatttgtt cttctgttgg atgcatgatg tttgatgaca tcaatgacgc taagccagtc
     1261 actgctaccc atgtaccagt atgcagagca tcgacatatt catccgataa ttgattgtat
     1321 ctttcatctt ctttaactat ttcacggaaa taattgtatg aaaaatcatg cattttcttt
     1381 ccgtccccat gttcatcaat gtacaatgcc atgtaaagac tatgatgctt ttttgcaaag
     1441 tagatatagt tcaaaccgag atcaatgatt ttatcaccag tacgttcaat agggaaaaca
     1501 tcttctttta gttgttcaaa gatagaatcc agcaacgtat tttttaaatc ttccatgttt
     1561 ttgaattcca gataaatcgg ctgtgtcgaa atccccatct ttttagcaat atttctcgca
     1621 gtaaatcctt taaacccttc ctttgcaaca acatcataag cagcttttag aatttgatcc
     1681 ttggtataga cttttcttct cattaaaact cccccacttc tttactgcag tatatgttgt
     1741 tttattgtac cctattttta gcattttttg caaacatttt actcaaaacg ttatatttta
     1801 aatttttttc agtcttcttt aacttttttt tgcaaaatta aaaaaatttg gttaaattca
     1861 atgggttccc ttacattttt agttttgacc taaatgatag ttgtccaaat ctttcatttc
     1921 aagttatagt taaagaaaat gaaaaagaag gtgtgtaatg gaaaacgaaa ctgacgttat
     1981 ttatattcat cctcaaaaac gaatcgtttc acagaaaaga aagtattttt atcttggttt
     2041 tacaggtgtt ttttttcttt ttattggctt gctttctaat actcctactg ataattggag
     2101 tggattgcta actattctta cctcgccaag caatcttttg acagattatt ttgctttagg
     2161 tgttttcgga agcgcattca taaatgtagg gattttgacc ttactttctg tgcttttagc
     2221 ttatcggcac aaggtgattt taaacggtcc cttatttgct tcgattctaa cagttaccgg
     2281 tttctctttt tttggcaaaa acctttataa ttctatctca atcattttag gtgtgtatct
     2341 atacgctgta tttgtcaata aacctttttc tcagtacatc atgatcggac tgtttggtag
     2401 cgtattatca ccggtcgtta gttatatcac ttttggtatg cgttttcctt tactgatagg
     2461 tattttattg gggaatttag ctggcatagc aattggtata cttcttccgc ccttagctgc
     2521 tcaaacttta gttttccatc gtggattcac actttataat attggattca cctctgggtt
     2581 gattgcgatg acttttactg ctgttttgag gttattcagc tattcaatcg tcgaaaatac
     2641 attggttttc aatgaatatc actttcctct catttggatt atttttggct ttttttcgct
     2701 gacagtcgga attggtttct attataattc ctttcggctt tcggggattc gagaaatttt
     2761 cgattcatct ggaaaattga caactgattt cattgctaat tctggtattg gtgctacttt
     2821 gatcaacatg ggcttagttg gtctgatgct gtcttcttat gttttgctgg ttggcggtca
     2881 gttaaatgga cctgtcatcg gtgctatttt atctgcggtg ggtttcagtg cttttggttg
     2941 tcatttaaaa aacagttttc cgatactagt cggaatattt attgcttctt tgtttggaac
     3001 ttttcatgag atcaccagta ctggcatgct tgttgcagct gtgtttggga caggtcttgc
     3061 gcccataagc ggtttttacg gcagttttta cggtgtaata gctggtgtgc tacatattgc
     3121 tcttgtccat aacgtcagca ctttgcacgg aggactaaat ctatataaca gtggtttttc
     3181 aactggtttc gttgcaggta tccttgtacc gatactagat aactttaccg ctgtcagaaa
     3241 ggaaaaaaag acacttggaa aaagaattat caaaaagaat catcgatgag cttcttactt
     3301 atttatattc ccatgaaata actgaaatac gtattggagt agaatttgct gaggaagggc
     3361 ttttcataga gatacagggt acggcagaaa ctcagccaga agatttagat gtacttgctg
     3421 atttgctgaa caatcctcgg gaccctagta tggaaatcta ctatcaagaa ctattaggta
     3481 atccccgaca tgatcgggaa gattatcatc tgttaggtag tttgattgat gacgtggaaa
     3541 tcatgtatgc ccagccgatt atcaatatta agatctttcg acgtgcttct cattcctatt
     3601 attaacccta ttttctattt ataaaagact gaatcaaaaa agcagctcct gaaagttcga
     3661 ttaaaatcta ctttcaggag ctgttcaagc ttgacattat tgattttcca atccttcata
     3721 cacttcatct gttacaggtt ctaaaaactc tgaattacca gcagtgatcg ccaaatgttc
     3781 aaaccaactg tcttttgtcg caccatgcca atgtttaatc cctttgtgcg ttacgacgac
     3841 atctccagcc attaatcgtc ttgctggctt tccttcttcc tgataccagc cttctcctcc
     3901 ggtcacaagt aagatttgat agccgtctgt atggacatgc cagtgattgc gacaacctgg
     3961 ttcaaaagtt acattaccta caccaacaga aacttcggga tcattcacta acatattcag
     4021 atagctttgc ccggtaaata cttgagcgta agcttcgttt ttttcacctg ctggaaaaat
     4081 cacgccattg tgtatttctt cgtgttttgt catcatttac gcctctttct tatcttcgct
     4141 attttcttct aaatagattt cttttgctaa actaaaagct gaccaagctt ttggccattc
     4201 tacataaaaa gctaaatggg taatgatttc tgctatttct tcactagtaa tgccattttg
     4261 cttgccaatc ttcagatgag ctggcaattg ttcaaaattt cctcctgaaa ttaatgcaga
     4321 tatggtgatg atactacgct gatgagcaga taattcttct ctggaccata cttgtccaaa
     4381 taaaacatca tcatttaatt ctgcaaattt tggtgcaaaa tctcctaatt gatctcgtcc
     4441 tgcggtttgt ttttctgcca tttctcttat tctcccttca cgactgttag gtgattcaac
     4501 tatggttcta aggcaacttt attttctatt gtttcttcgc atttcatttt aaatgtagtc
     4561 tttcagcctg tccaatgctt agtttattca gtcgatatgc tttttaagca tagttgctaa
     4621 cgcttttttt attttaaaaa aaacaagtta ttaaataagt ctttagttgg atgttttttt
     4681 gagatcaatc ttttatactt atgatgaact tacaaaattg tttgttttct gtcatatcaa
     4741 aaaatggcgc agttagttgc ttttctagta aagtatagtt aacaaagaac ctctaaggag
     4801 ttgatgaata atgaatattg ctgcctctcg aaaactgata aatttcatat ccattatcgg
     4861 attaggccta tcaatcgcgc tgacgattta ttttattaat ttaggtgttt tcaaagattt
     4921 gaatgcgtta agaggattag taggtgattc catcatttta ggaccgatta tttttgtctt
     4981 catccaaatc ctgcaagtag ttattccaat cattcctgga gggatcagta ctgcagctgg
     5041 tgtcctgata tttggccctt atgctggatt tatctataac tatattggaa tctgcattgg
     5101 ttcgattatc atttttctgc tagggcgtcg ttatggaaag ccattcatac tttccatgat
     5161 tagcgataag acatataaca aatatattgg ctggctggat aatcaaaacc gttttgagaa
     5221 gctgtttgct ctagctattt ttcttccagt tgctcctgac gatgcgttat gtttgatggc
     5281 tggattgaca aacatgtcag tgaaacgata tacactaatc attttgattg ctaaaccact
     5341 gtcgattttc ttatatagta tggccttgat ttatggaggt caatatctaa gtggtcttct
     5401 tggataatat ttattttgta aaattagtca ttgattgaca atgt
//
LOCUS       DAFLWQ010000131         5312 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.135, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000131 DAFLWQ010000000
VERSION     DAFLWQ010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.135"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="L1V16_002811"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="L1V16_002811"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBN1277082.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="L1V16_002812"
     CDS             complement(1297..2133)
                     /locus_tag="L1V16_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1277083.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="L1V16_002813"
     CDS             complement(2317..3534)
                     /locus_tag="L1V16_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBN1277084.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3683..3862)
                     /locus_tag="L1V16_002814"
     CDS             complement(3683..3862)
                     /locus_tag="L1V16_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277085.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3917..4000
                     /locus_tag="L1V16_002815"
     tRNA            3917..4000
                     /locus_tag="L1V16_002815"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..4818)
                     /locus_tag="L1V16_002816"
     CDS             complement(4240..4818)
                     /locus_tag="L1V16_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277086.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(4824..5207)
                     /locus_tag="L1V16_002817"
                     /pseudo
     CDS             complement(4824..5207)
                     /locus_tag="L1V16_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347134.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1654 a         1082 c          838 g         1738 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
     4741 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     4801 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     4861 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat ttcatgtgca
     4921 gcacgtaatg cattccctgg agttgtcaaa gagaaaatta attctgctaa gcttattatt
     4981 gaaaatactg ataacttata attatatcgt ccattgacaa tcaaatataa actaactata
     5041 cttgttagaa caaaaaaaca ggcgttgact tgttcttgat tagttaaaaa tatcaataaa
     5101 ggaatactta cccaatatat ttttctattt atttcttctc ctcttaagag ttgaaaaaac
     5161 ggataaaaag ttagtaaact aaatgctact ggccactgat agttcaaggt ggttgctctc
     5221 caaccggttt cccccattac tgtcaatggt attaaacagt atatagagca aaccaataat
     5281 aaatttttaa catttatttt ctcaaaaaca ta
//
LOCUS       DAFLWQ010000132         5207 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.136, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000132 DAFLWQ010000000
VERSION     DAFLWQ010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.136"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            34..1368
                     /locus_tag="L1V16_002818"
     CDS             34..1368
                     /locus_tag="L1V16_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277087.1"
                     /translation="MDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAY
                     GLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVV
                     NLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITT
                     YTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQF
                     PWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQS
                     KHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAAD
                     NNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEIT
                     TKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            1355..2989
                     /locus_tag="L1V16_002819"
     CDS             1355..2989
                     /locus_tag="L1V16_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277088.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            3164..3997
                     /gene="msrA"
                     /locus_tag="L1V16_002820"
     CDS             3164..3997
                     /gene="msrA"
                     /locus_tag="L1V16_002820"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBN1277089.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            4110..5066
                     /locus_tag="L1V16_002821"
     CDS             4110..5066
                     /locus_tag="L1V16_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBN1277090.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
BASE COUNT         1825 a          806 c          951 g         1625 t
ORIGIN      
        1 agtttttatt atggagaaaa gttttttaaa aagatagatg ctgctttttt atttagttgt
       61 ttatatactt ttgcaactta tcgaacagtt gatatctatt atcgatccgc aattgcagaa
      121 gcaatcgctc ttacgattat cccagctgtt ttatattatg cttatggatt gatattcaat
      181 agagaaaaaa aagtcatcgc tttatctgtc agtataagtc tacttgtgta tactcatgtc
      241 ttaactacac tattgtgtag tgcattgatt gcttgtatga ttatagttcg tttgttttta
      301 agcaagcaaa taaaaaacga tataaaattt gtggtcgtga atttagtaaa ggctgttttt
      361 ttgacttgtg cattaactag ctatttttgg tatcctatgt tgcagcagat gaattatcaa
      421 gaaatacaca gtcccttcaa aacagatttg cagctagaag cactttctat ttcagatagt
      481 atcattcaag cgttaaataa cgatattaca acatacacta tggggttatt aggattggtt
      541 gcgttgattt ttcctttatt catactgaaa gaaatggaga aaaaagaaaa aatcatctat
      601 gttggcgtag tttctacatg ggtatgcgta actaatttat ttccatggtt tttgtttcaa
      661 aaaacaccga taagcttgct ccagtttcct tggcgtatct taggtatcca aatctttttt
      721 tcttcaatga tcataacgct tgtttttatg aaaaagacta tgaataaaaa atattcatgg
      781 ttaatcattg gcgctactgt ggtgtttcta ctcgtcacgt ctatagcagc aaaagaaaat
      841 tacgcaaaag ttatccaatc aaaacacggt catattgtta tcaatgaaga aacactccca
      901 cgttatacaa catcagatat gggaggatta tacgattacg ccccaacaga agcgataaaa
      961 gaaaggcctc acttagaaaa acatgaagta aaagtaggag aatcgtggga aaaagggaag
     1021 tataaagctg cagataataa cattacttac acagtggcaa gcaacaaaaa gcaaaaagtg
     1081 acagtaccag tatatgctta tttaggtaca caggtaaaag taaacggtaa agtcgtaaat
     1141 gactcttata aaaaacatgg cttagtgaat gtggatgtaa atgctggaga aaataagata
     1201 gaaattacaa caaaatatac tccaactgct ctcatggctt tatggatcag tattctgact
     1261 tattgtttag tggtgtattc aagttttaaa cgatttgcac ctaataagtt gaaagattct
     1321 cgatatgtga ctaaaaagga gataaacaag aagaatgaaa ataaataaaa aagtagtaat
     1381 attgagtgga ttaattatag ttagtagtat atattctttc atctttttca aaaatacaca
     1441 gagtatttat accactggag atctttcttt tcacttatct cgaatcaagg ggttatcgac
     1501 tatttttacc agtccgatta attatgagac attcaattat actggatatg gtgtaaatta
     1561 tttttatccc tttctgactt tttttccagc tgtaatgtta tattggatga caaaaaattt
     1621 gattgtaagc tatattattt acgtttggtt attgaacttg tgtacaacac tcgtagctta
     1681 tcattatggc gagcggtttt taaaacaaaa aaaagcggca tttttattta gttgtctcta
     1741 tattttctct gcttatcgga cagtagacat ctactatcgt tccgcaattg ccgaagctat
     1801 cgcaataaca cttgttatcc ctgtattatt ttatgcttat caaatcatct ctggaaaaga
     1861 agaaaagtat ccgtctgtaa agctagcatt gagtatgagt ttgctagtgt acagccatgt
     1921 actatcaaca ttaatgagta cagcattaat tatcattttt atttttattc gtttggtttc
     1981 taaaggtttc aagaatgcag attttattgc tatatttaaa aaattattta gtgcggcagg
     2041 aatgacattg gttctgacga gtgctttttg gtatccgatg tttgaacaaa tgctctacca
     2101 aaaaatcaac aaacctagcg tgacaaattt atatgctcat gcatctaatg tgttcgatag
     2161 tctgactgaa gctatgaaca acgacttaac tacttactca atgggactag ttggtctgtt
     2221 atctttatgt attcccctga ttttatttaa aaaattaaca aacatagaaa aaaagattta
     2281 ttatggtacg tgtttgactt ggctagctac aactagtttg gtgccatggt atcttctgca
     2341 aaatacgcca gccaaattgt tacaatttcc ttggcggatc ttaagcttgc aaataatatt
     2401 ctcttctctg atattaacga tgatattttt caaaaataga agatacaata agacaagaga
     2461 actattttat ttatttatga ctgttttgtt attaatcact ttaactgttt ctagtaaaaa
     2521 aaatttcaat caaaaaataa tttctcagcc gggacatatt gttgtaaaca aagaaacagt
     2581 agaggcgtat accactaaag gaatggatta ttttttatat gattattctc ctatcgcttc
     2641 attggagaat aaggagcata taataaaaca cgaagcaaag attggcagtc aatgggtaaa
     2701 ccttccttat aaaacaactg gtagttctat catatataga gtaactaatg agaagagcca
     2761 agtaatcaca cttcctgtat atgcttattt aggaacgaat gtagaaataa atcatcaacc
     2821 tgtaaaggag caggtgaatg ctaatggatt ggtacaaata agcggagtca aaggagttgc
     2881 tgatattaaa gtaagcacaa gttatacagt aacgactatt atttcttatc ttgttacatt
     2941 aactgcatat ttatgtttat tttttaaaat agttttccat aaaaggtaaa ttaacttttc
     3001 atttataaaa taaattgatt aaaaaggaga atctgtcgat aaggattctc tcttttttat
     3061 acgaaaaatc tgtaggggga tgaagtaatc gcttatttcc tcactttatg ataaattaca
     3121 gctaaagtca ctagcttgtc ttcttcggaa aggaggagaa tctatggatg aggaacaaat
     3181 attcattcaa acactttata atctgatttt gaatccgaat acacgagatt gggaacgaaa
     3241 agtattgatt cagacaaaga atgacataag agaaaatata tccgttaaag aacagttatc
     3301 aaaactagaa gcaacactac gtccattagc tatccgaatg aatctgacgc ctgatgtaat
     3361 ggacttttat ttattgatta cggaaggatt tgataaggag caaaaatatg acttttccaa
     3421 gcatgccatg caagatgctg actatcaaga acgtgcagta tttgcagggg gatgtttctg
     3481 gtgtatggtc gagccgtttg aatcgaaaaa agggatccta tctgttttgt caggatacac
     3541 gggcggacat gttgaaaaac caaattatga tcaagtaagt ggtggttaca caggtcatgt
     3601 ggaagctgtg gagatcattt atgacacaag agaaataagt tatagcgagt tgctgacaat
     3661 ctattggcaa attactgatc ccacagatac atttggacaa tttcaagata gagggaagca
     3721 atatcgtcca gtgatttttt atcaaggcga acgacaaaaa gaattagcgg aacaatcaaa
     3781 acagaaacta gacagttcag gaactttcca ccaaccaatc gtcacaaaaa tcgaaccagc
     3841 cggtacgttt tggccagcag aaaactatca tcagcaattt tacaaaaaac aaccgaaacg
     3901 ttataaaaaa atccagcaag cacgtaatca atttctgatc tatcaacgag taaaaaacaa
     3961 atggcaaaaa aatatacgaa aaaatcattt tgattaactc cttttcttta aaatgtagta
     4021 aactaaaaat agaaaaaaga aagcgtttta aaaagatttg atgaggagga gaaaaattgt
     4081 atattgcaga tagtgcacgt tatgaaaaaa tggaatatcg taaatccggt cattcaggtt
     4141 tgaaattacc gattttatct ctcggattat ggcaaaattt tggtgattat gatcctatcc
     4201 ataatcaaag agagatttta agaggcgcat tcgacatggg aattacccat ttcgaccttg
     4261 cgaataatta tggaggccct gctggagctg cagagaaaaa ctttgggcgt atttttagag
     4321 aagattttca agcctaccgt gatgaactga ttatttctag caaagcaggt tatcatatgt
     4381 gggaagggcc atatggggaa tggggctctc gtaaatccat catttcaagt tgtgaccaaa
     4441 gtctccaaag aatggggcta gattatgttg acatcttcta tcatcatcgc ccagaccctg
     4501 atacaccttt ggaagaaaca gcagaagctt tgatgcaact tgtaagacaa ggaaaagcat
     4561 tatatattgg tatatccaac tataatggag aagatacaaa aaaaatgact gaaattttaa
     4621 aaagaaagga agcaccgttc attattcatc agatgcgcta caatatgttt tctcgtgcac
     4681 tactagaaga cgatctatct ccagtattag aagaagaagg gctaggggca atcacgttca
     4741 gtccgcttgc tcaagggttg ctgacaaatc gttatctaca tggtattcct gaagattcta
     4801 gagcacatcg taaggaaata ccattccttt cagaagaaca agttggatca actctggaaa
     4861 aaatcaaagc actgcaaaca atcgccgtat cacgaggaca atcattagcg caaatggccc
     4921 ttgcatggaa tttgcgacaa aaatctgtta caagtgtact ggtcggagca agtcggttaa
     4981 gtcagttaca agaaagtgtt cgaatgatgg ataatttaga tttctcacca gaagaagaat
     5041 tgagaatcga ccaaattcta gaatagaaac gatgtaatca aactttttat ccatatatta
     5101 aaaaaaacaa aagatgacat caagaatcga atgaagatcg tctgttattg aacatcatat
     5161 tttttgtcgt tcaaaataaa aatgatcgaa ggctaggagt gaatttt
//
LOCUS       DAFLWQ010000133         5191 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.137, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000133 DAFLWQ010000000
VERSION     DAFLWQ010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5191
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.137"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            137..748
                     /locus_tag="L1V16_002822"
     CDS             137..748
                     /locus_tag="L1V16_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBN1277091.1"
                     /translation="MYFILPTLYSLLCVMAPCIIYMVFFCKKNTLKHNILILIFMLYC
                     WKVFELTGTGGLTDIFYRPDTGRKFSLVQGSVNLVPFSGLNISFILNIVMCVPLGFLL
                     PIIWKSYRKIVPVFLAGALFSLIIEVSQIITTRATDIDDLIANTFGAVIGFILWAVLS
                     RVVSLKDKSSTVDYLEPYIYILIGFTGKFLLYFPFWFAFEVLS"
     gene            821..1750
                     /locus_tag="L1V16_002823"
     CDS             821..1750
                     /locus_tag="L1V16_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBN1277092.1"
                     /translation="MKRFLKWGLVLLASLIVILMCTAVVISYVNRPYARAVYDRIKRI
                     LDKDFYDHLYLGSSFEIINLDTMDIHSYMKKDQEELPASLSKLFTIDYALSVLSLDEQ
                     ITISPTALDMQKADSSTAHLQEGDILSVYDIICAMVLPSGNDAAYSLAIYTGGKLDPD
                     AKNDEERYQSFMKNLDRYLSEQGYKHTHFTDAAGYDSNATTSAEDLTKVAAKLLKNDK
                     FAEIVAKETYRAKSIKGNVYNWNTTNQFMQQDNRYFTEGVKGVKTGSFDGRYNLCVYY
                     TSSSDNHYLLVSFGSESDSRRYVDVQNLLHNLP"
     gene            1819..2645
                     /locus_tag="L1V16_002824"
                     /pseudo
     CDS             1819..2645
                     /locus_tag="L1V16_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033645.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
     gene            complement(2693..3871)
                     /locus_tag="L1V16_002825"
     CDS             complement(2693..3871)
                     /locus_tag="L1V16_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBN1277093.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHHYTPQTMSNMTKSFTEEVTSFKERELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILIDLQERG
                     VKNVLLFITDGLKGMAGAVQRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKKAALEARGAFAEKWKTSYPKMVESILSNDYLLTFYDFPLAIRKTIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLASMFTE
                     "
     gene            3969..4067
                     /locus_tag="L1V16_002826"
     CDS             3969..4067
                     /locus_tag="L1V16_002826"
                     /inference="COORDINATES: protein motif:HMM:NF013068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1277094.1"
                     /translation="MKERGLSGVKMVISDAHIGLTKAVKEYLLCAS"
     gene            4098..4499
                     /locus_tag="L1V16_002827"
     CDS             4098..4499
                     /locus_tag="L1V16_002827"
                     /inference="COORDINATES: protein motif:HMM:NF013068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1277095.1"
                     /translation="MSDKFSKKISSDIKEDFKAIFKTASIELAGERKQLIMDKYGEDK
                     KVATACKILDEGFEDAMQVMVLPENIRQRLRTTNVLERLNEEVRRRERVVRIFPNCDS
                     VIRIIGALLMEKDDEWTSAPRKYLEFDRNEI"
     gene            complement(4706..>5191)
                     /locus_tag="L1V16_002828"
     CDS             complement(4706..>5191)
                     /locus_tag="L1V16_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1277096.1"
                     /translation="LKEAIDQIKTAVLYPHNGLPILLMGVSGSGKTFLAEKIYEYAKE
                     QQVIESNAPFIAYNCAQYFNFSINKIVENLTILDAMKVLRLVQKAVKELEKLMGIEFS
                     NNQLFLLYMHCCSMIERILRKESVDEQADIKEYIQKEGHNYEISKYPAYKTKFESTVI
                     K"
BASE COUNT         1641 a          879 c         1003 g         1668 t
ORIGIN      
        1 cctctaggaa aaaattaact agcaccacgg gttatgatat aataaaatgt attataggca
       61 tttttttaca agaaatagaa gcttgaagtt tatatgaagt tataaaattt aatttatatt
      121 ggaaggagga aaataaatgt attttatact acctacactt tatagccttt tatgtgtaat
      181 ggcaccatgt attatttata tggtattttt ttgcaaaaaa aataccctga aacacaatat
      241 cctgattttg atttttatgc tgtactgttg gaaagttttt gaattgactg gtacaggtgg
      301 actaacagat attttttata gacctgatac aggtaggaaa ttttctctag tacagggcag
      361 tgttaatctt gtaccattca gtggactaaa cattagcttt atattaaata tagtaatgtg
      421 tgtgccctta ggattcttac taccaatcat atggaaaagt tataggaaaa tagttcctgt
      481 tttcttggct ggggctctat tttcactaat tattgaagtc tcacaaatta taactacaag
      541 agcaacagat attgatgatt taatagcaaa tacctttggt gcggttatag gctttatact
      601 gtgggctgtt ttaagtagag tggtgtcctt gaaggacaag tcatctacag tagattattt
      661 agaaccttat atttatatat tgattggttt taccggaaaa ttcttactgt attttccttt
      721 ctggtttgct tttgaagtat tatcctgata attccataga aaataatgag tttgagttga
      781 gaaagaatat tcttgtacac aactctggaa aggaggaagt atgaaaagat tcttaaaatg
      841 ggggcttgtt cttttagcgt ctttgattgt gattctaatg tgtacagcgg ttgttatttc
      901 ttatgtgaat cggccgtatg caagagctgt ttatgatagg attaaacgca ttcttgacaa
      961 agatttttat gaccatctat atctaggttc ttcatttgaa ataataaacc ttgatacaat
     1021 ggatattcat agctatatga aaaaagacca agaagaatta cccgcctcat tgagcaaatt
     1081 atttacgatt gattatgcgc ttagtgtcct aagtttagat gaacagatta caattagtcc
     1141 tactgcactt gacatgcaga aagctgactc atctactgca catcttcaag aaggagatat
     1201 tttatctgtt tatgacatta tctgtgctat ggtcttaccc tcaggaaatg atgcagctta
     1261 tagtttggca atttatacag gtggaaaact tgatcctgat gcaaagaatg atgaagaacg
     1321 ctatcaaagc ttcatgaaaa acttagatcg ttatctaagt gagcaaggct ataaacatac
     1381 tcattttact gacgctgctg gctatgactc caatgctaca acatcagcgg aagatttgac
     1441 aaaagtagct gcaaagctac taaagaatga taaatttgca gaaatagttg ccaaggaaac
     1501 ttatagagca aaatcaatta agggaaatgt ttataactgg aatactacga atcaatttat
     1561 gcaacaagat aatagatact ttactgaagg tgtaaaaggt gtaaaaactg gatcgtttga
     1621 tgggagatac aatctatgtg tgtattatac atctagttct gataaccact atttacttgt
     1681 aagttttggt tcagagagtg atagtaggcg ttatgtagat gttcaaaatc tattgcataa
     1741 tctgccttga aatttcgtgc ctttaagcgc gtatctaaag tttctttgaa aagtttgaga
     1801 atgaagaaag tgagcagtcg aaaaacggtt gctcactttt ttgccctaaa atcgaaaaaa
     1861 tataaaaaag tcctttacaa cacgtctcag gaaaaactgc taagtcaatt ctaatatctt
     1921 gtggagcaag acttgcacct tttgatataa gagagcttag agaactaatg agcgaagatg
     1981 aactagaact cgataaaatt ggagatagaa aaactgcctt gtttgtaata atatcagata
     2041 cagatgatac atttaatttt gtagtttcaa taatgtattc tcaattattt aatctactat
     2101 gtgataaggc agatgatgtg tatggtggaa gacttccagt tcatgttagg tgtctacttg
     2161 atgagtttgc aaatatcggt ttgattccta aatttgaaaa actaatagcg acaattcgtt
     2221 caagagaaat atcggcaagt ataatactgc aagcacaatc tcaattaaaa gcaatttata
     2281 aagaccatgc agatacaata gttggtaact gtgactctac actttttcta ggaggaaaag
     2341 aaaaaacaac agtaaaagaa ttatcagaaa ccttaggaaa agaaaccata gacctatata
     2401 acacatcaga aacaagatca aatcaaaaat cttttggtct aaattatcaa aagactggca
     2461 aggaacttat gagtcaagat gaaataactg taatggatgg tggtaagtgt atttaccagc
     2521 taagaggagc aagacctttt ctatctgata aatttgatat tacaaagcat aagaattaca
     2581 aattgttgga agattatgat aagaaaaact tgtttgatgt agaagagtat ttaaaacaaa
     2641 gatagcgtaa aatattttgt gtaaataact cgtccttctg caaaataatg ggttactcag
     2701 taaacattga agctaatgta tccgtcactt gttggaagcc tttatggctt ctatttaaga
     2761 atttttgatt gtatgtatca aagatggata ctaggaaacg ctctagtgat tcttcatttt
     2821 gaaactgctc ttttctgtgg ctgtatttct tgatttgctt attaaaggat tcaatcaagt
     2881 tcgtagagta aatagtcttg cgtatggcta atggaaaatc atagaaagtg agcaggtaat
     2941 cgttcgaaag gatcgattcc accatttttg gataactggt tttccatttt tccgcaaaag
     3001 caccacgtgc ttccaatgcc gcctttttag atgacgcttg atacaccatt ttaaaatcat
     3061 cacagacttc cttacgatca tcgacacgca ctttgtgact gatattacgg gaaacgtgca
     3121 cacagcaatg ttgaaaacgg gctttggggt agaaccgctg cacggcccct gccatcccct
     3181 ttaagccatc cgtgatgaaa aggaggacgt ttttcacgcc acgttcctgg aggtctatta
     3241 aaatctcttc ccaaatcgtg atagattcag ttggtgcaat cgcatagctc aacacttcct
     3301 ttgaaccgtc cgggcgaatg ccaactgcga tatgaatggc ttccttggcg acggttttcc
     3361 gctttaaagg gatataggtt gcgtccatat aaatagcggc ataacggtca tgaagctcac
     3421 gttccttaaa tgaagtgact tcttccgtaa atgatttagt catattggac atggtttggg
     3481 gcgtgtagtg atgcccatac attttctcaa tcaagtctgc gatttccgac atggtaatac
     3541 cttttcggaa gaggtgaatg acggtctcct ctaaggtatc attcgtccgt ctataagcag
     3601 gaacagtctg ttgcttgaac tcgccgttgc ggtcgcgcgg aatctggaga tgaagttccc
     3661 cgtactcggt cttgaccgta cggtcatagg agccgttacg agaattaccc gtgttaaaac
     3721 caatgcgatc gtacttttcg taatcgagga aagccgttaa ctccgttttg agaagcgtat
     3781 tgacagcttt ttccaaatgg acacggaata attcattcaa atcgccttta ttcgctagag
     3841 tctttagaat ttctgtagta aaatcgttca tatggaagtc ctcttttctg tgaatgtgtt
     3901 gtggtaactc tattctactg aagggacttc cttttttcta tttacacaaa atattttaca
     3961 ctctcggatt gaaagaacgc ggtctttcag gagtaaagat ggtcatctcg gatgcgcata
     4021 tagggctcac aaaagctgtg aaagaatacc ttctttgtgc gagctagcag agatgccaag
     4081 cacatctcct tcgcaacatt tccgacaaat tctccaagaa aatctcaagc gatatcaaag
     4141 aagactttaa agccatcttc aaaacggcaa gcatcgagct ggctggagaa cgtaaacaac
     4201 ttattatgga taaatatggg gaagacaaga aagtcgcaac tgcctgtaaa atattggatg
     4261 agggcttcga agatgccatg caagtaatgg ttttaccaga aaatatccgt caacgattga
     4321 gaacaacgaa tgttcttgaa agactaaatg aagaagtacg ccgtcgtgaa cgtgttgtcc
     4381 gaattttccc aaattgtgat tctgttattc gtatcatcgg tgctttattg atggaaaagg
     4441 atgacgaatg gacttctgca cctagaaaat atcttgaatt tgatcgtaac gagatttagc
     4501 acattaagcc gccaatagta taatatactg gtgagaagta tcaagagacg cttcgctttt
     4561 tgctcttgac acttcttacc agcatattgg accgtagcta ggctcaacaa ggcaaaacat
     4621 cgtactttga gatttccttt ttacacaaga ttttggactt gacacagccc ctatggttct
     4681 taccttgttt atgcttattt aaatcttact ttattacagt actttcaaac ttcgttttgt
     4741 aagccgggta ttttgatatt tcataattat gtccctcttt ttgaatatat tctttgatat
     4801 ctgcttgttc atctacactt tctttgcgta aaatacgttc gatcattgag cagcagtgca
     4861 tgtaaagcaa gaacaattga ttgtttgaaa attcgatccc cattagtttt tcgagttctt
     4921 tgacggcctt ttgtaccaat ctcaaaacct tcattgcatc aaggatcgtt aaattttcta
     4981 cgatcttgtt aatcgagaaa ttaaagtatt gagcacaatt ataggcgata aatggagcat
     5041 ttgattctat cacctgttgt tccttggcgt attcataaat tttttctgcc aaaaaggttt
     5101 ttcctgaacc gcttacaccc atcaataaaa tcggtaatcc gttatgagga tacaagacag
     5161 ccgtcttgat ttgatcgatc gcttccttta a
//
LOCUS       DAFLWQ010000134         5054 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.138, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000134 DAFLWQ010000000
VERSION     DAFLWQ010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5054
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.138"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            102..818
                     /locus_tag="L1V16_002829"
     CDS             102..818
                     /locus_tag="L1V16_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HBN1277097.1"
                     /translation="MVDNYERKNILKKKSIGCRMKIVAIVPMKLNNKRLPQKNTKAFT
                     NGKPLCYYILSTLLKVKQIDKVYVYCSNPDIKEFIPEGVTFLKRSSSLDQDTTSITQV
                     LAGFTKEVEADVYVMTHTTAPFISEKSIEKGLDAVLTGEYDSAFAAKKLQDFLWKDGE
                     PFNYELDNIPRTQDLPPLYEETSGFYIYNRNVMTELHRRIGKKPCIVEVGEIESVDID
                     EAEDFMIADAIYNHLILQGS"
     gene            837..2420
                     /locus_tag="L1V16_002830"
     CDS             837..2420
                     /locus_tag="L1V16_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase catalytic domain-containing protein"
                     /protein_id="HBN1277098.1"
                     /translation="MNNVQILDCTLRDGGYCNNWEFGFDNTKKIISGLIESGIEIIEC
                     GFLTNKTVYNKNVTKYTTLEELAQIIPEKREGKLFVAMMNYGEYNIEDLPDYDGSSID
                     GIRIAFHKKNCNEALKLCREIKKKGYLVFVQAMVSLNYTDEEFLAVIKNVNQFKPYAF
                     YIVDSFGMMKGKDLTRLFYMIEHNLEKDIQIGFHSHNNMQLAYSNAQKLITVQTNRSL
                     IIDSSVYGMGRGAGNLNTELFVEYLNDNAGKKYQLKPLLYIIDEILNSFYQKSYWGYS
                     LPNYISAVHNAHPNYASYLSYKNTLTIEAMNEIFEMMDEEKKVSYDKQYIEDLYYKYM
                     ETGKIQEEYMEELRKFLSDKKILLIAPGKSSVDEVERIKEFVTKEEVVIISVNFEYSH
                     IDIDYVFLSNLRRFHELPKESRTKCIVTSNIQASDVYLRTSYKKLLSEREVVRDNAGL
                     MAIRFLADMNVDEIFLAGFDGYSHNEDENYGEQSMEIITKFALLDAMNVQMRDELSEL
                     AKKVKVTFLTDPRWVRIDK"
     gene            2555..3133
                     /locus_tag="L1V16_002831"
     CDS             2555..3133
                     /locus_tag="L1V16_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277099.1"
                     /translation="MISILCIVAYHANLRLNYNADGIIVHGSLTANQIFLNYIGIWGQ
                     LGVNCFIFISAYFLSEKRNIHFENVLGIVLECIFYSVLVYGILCACGIETFSLNSFVK
                     EILSFALGRYWFITSYLALYILSPYLNIMLNNLEKLQLQKISMLLFIGVCCYRMLFKT
                     SLFGDCAVLIALYVICYTLKKTIIIFLRDTES"
     gene            3079..3597
                     /locus_tag="L1V16_002832"
     CDS             3079..3597
                     /locus_tag="L1V16_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277100.1"
                     /translation="MLYTEKNDNNIFERHRIIGTIVCITVIPLLISIGILFKFIPNAM
                     VNQMVHIGSPLMVIASIFLFYVFKNFSFYSKYINKLARTSLGVYILHENHYFIDGMKS
                     RGLIWDGIFGLGKRFLDRDFWIWFIIAVVVVCIICMAIDVVREKFERQIFKIKSVKNL
                     CKLMNHVINIYP"
     gene            3605..4645
                     /locus_tag="L1V16_002833"
     CDS             3605..4645
                     /locus_tag="L1V16_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBN1277101.1"
                     /translation="MRRKEVKVISFGELLLRLAAPGYSKLFQRDSLETTFCGGEANVA
                     VSLAIFGYQSEFITKLPDSDVGYAAANALRYFGVNVDNIIFGEGRMGLYYLEKGAAQR
                     PSKVIYDRKFSAISLADSDEFKWKEILNDANWFHWTGINPALSENLFETSLDACQAAK
                     KRGITISCDLNYRSKLWTSEEAKEKMEQILPLVDICICNEEDAEKVLGIKAEHTNINS
                     GELNKDGYVQVAREIHKKFGCRYVATTLRRSYSASRNGWSAMLYEAEKDKAYFSTEYN
                     IQIVDRVGGGDSFSAGIIYALCENMSGQKAIEFATASSCLKHTIEGDFNRTTIEDVYN
                     LMNSGGNGRVLR"
     gene            4894..>5054
                     /locus_tag="L1V16_002834"
     CDS             4894..>5054
                     /locus_tag="L1V16_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1277102.1"
                     /translation="MTYTYLTTDELVIIESYLKINQSVAKTAHCLNRSSQTIHKVYLF
                     FKQRKSALE"
BASE COUNT         1868 a          577 c          990 g         1619 t
ORIGIN      
        1 aagcagttgt gttatagagg aagaaacatt atttcaatga ttaagagtcg agagcacaaa
       61 cggtagacga tgttattttt ataaaaagat ataatttatt aatggtcgat aattatgaaa
      121 ggaaaaatat tcttaaaaaa aagagtatag gatgtcgtat gaaaatagtc gctatagtac
      181 caatgaagtt aaataacaaa agattgccac aaaaaaacac gaaagctttt accaatggaa
      241 aaccattgtg ttattatata ctttcaacac ttttaaaagt aaaacagatt gataaagtgt
      301 atgtctattg tagtaaccca gatattaaag aatttatacc agaaggtgta acatttttaa
      361 agagatctag ttccttagat caggatacaa cgagtattac acaggtatta gccggtttca
      421 caaaagaagt agaggctgat gtatatgtaa tgacacacac aacagcacca tttattagcg
      481 aaaaatctat tgaaaaagga ctagatgccg tgctgacagg agaatatgat tctgcatttg
      541 ctgcaaaaaa attgcaagat ttcttatgga aagacggtga accatttaat tatgaattgg
      601 acaatattcc tagaacacag gatttgccgc ctttatacga agaaactagt ggattttata
      661 tttataatcg caatgtgatg accgagttgc atagaagaat tgggaaaaaa ccttgcatag
      721 ttgaagtagg tgagattgag tcagttgata ttgatgaagc cgaggatttt atgattgctg
      781 atgcgattta taatcatctt attttacaag gtagttaaga cagggggaag gttaggatga
      841 acaatgtaca gattttagat tgcacactta gagatggggg ctattgtaac aattgggaat
      901 ttggatttga taatacaaaa aaaattattt ctggacttat agaatcagga attgagatta
      961 tagaatgtgg gtttctcaca aataaaacag tatacaataa aaatgttaca aaatatacga
     1021 ccttagaaga attagcacag ataattcctg aaaaaagaga aggaaaatta tttgtagcaa
     1081 tgatgaacta tggcgaatat aatatagagg atcttccaga ttatgatggt tcatctattg
     1141 atggaattag gattgcgttt cataaaaaaa attgcaatga agcgttgaaa ttatgtcgtg
     1201 agataaagaa aaaaggctac ttagtttttg ttcaagctat ggtatctctc aattatacag
     1261 atgaagagtt tttagcagta ataaaaaatg tgaatcagtt taaaccatac gctttttata
     1321 ttgttgatag ttttggaatg atgaaaggaa aagatttaac tcgtcttttt tacatgattg
     1381 agcataatct agaaaaagat atacagatag gttttcactc acataataac atgcagcttg
     1441 catattctaa tgcacaaaaa cttataaccg tacaaacaaa tcgaagcctg attattgatt
     1501 cttcggtgta cggaatggga agaggagcag gtaatcttaa cacagaacta tttgtagaat
     1561 atttgaatga taatgcagga aaaaaatatc aattaaaacc attattatat ataattgatg
     1621 aaatactaaa tagtttctat cagaagagtt attggggata ttcattacca aactatattt
     1681 cagcagttca taatgctcat cctaattatg caagctatct gtcatataag aatactttaa
     1741 caattgaagc aatgaatgaa atattcgaaa tgatggatga agaaaaaaag gtatcttatg
     1801 ataaacaata tatagaagat ttatactaca aatatatgga aactgggaaa atacaggagg
     1861 aatatatgga agaactgaga aaatttctct cagacaaaaa aattctactg attgcaccag
     1921 gaaaaagttc tgtagatgag gtagaaagaa taaaagagtt tgttaccaaa gaagaagtcg
     1981 taataattag tgtaaatttt gaatattctc atatagatat agattacgta tttttaagta
     2041 atttaagacg ttttcatgaa ttaccgaaag aaagcagaac taaatgtatt gttacatcaa
     2101 atatacaagc atcggatgta tatttacgga cgagttataa aaagttgtta tctgaaaggg
     2161 aagttgtaag agacaatgca ggattaatgg caattagatt tttagccgat atgaatgtgg
     2221 atgaaatatt cttagctgga tttgatggat attcacataa tgaagatgag aattatggtg
     2281 agcaatccat ggaaattata acaaaatttg cattattaga tgcaatgaac gtgcaaatga
     2341 gagatgaatt gtcagaatta gctaaaaaag taaaggtgac atttttaacg gatccacgtt
     2401 gggttcgaat tgataagtag tagtaataat gtttttaaaa ttttgataaa gagatagtga
     2461 gagaataaaa atgggtaaag tcttaaataa aaaagaagaa aaatatttaa gggccgatgg
     2521 ggcgagatga aactctaatt ttgaactttt aagaatcatt tctatattgt gtattgttgc
     2581 ttaccatgct aatttgcgtt taaattataa tgcagacgga attatagtac atggttcatt
     2641 aactgctaac cagattttct tgaattatat tggtatttgg ggtcagctag gagttaattg
     2701 ttttatattt atttcggcat attttttaag tgagaaaaga aacattcact ttgaaaatgt
     2761 tttgggaatt gtattagaat gtatttttta tagtgtatta gtttatggaa ttctttgtgc
     2821 atgtggaata gaaacatttt cattgaacag ctttgtaaaa gaaatattat catttgctct
     2881 aggtagatat tggtttatta catcctattt agcattgtat attctaagtc cgtatttaaa
     2941 tatcatgctt aacaatctgg aaaaacttca gttgcaaaaa ataagtatgt tattgtttat
     3001 aggtgtatgc tgttatcgta tgttatttaa aacatctttg tttggggatt gtgctgtttt
     3061 aattgcacta tatgtcatat gttatacact gaaaaaaacg ataataatat ttttgagaga
     3121 cacagaatca taggaacaat tgtatgtata acagttatac cacttctcat atccatagga
     3181 atacttttca aatttatacc aaatgcaatg gttaaccaga tggttcatat tggttctcca
     3241 ttgatggtta tagcaagtat atttttattt tatgtattta aaaatttttc attttacagt
     3301 aagtatataa ataaacttgc gagaaccagt ttaggggtat atattttaca tgaaaatcat
     3361 tatttcattg atggtatgaa gtctagaggc ttaatatggg atgggatatt tggattaggc
     3421 aaaaggtttt tagataggga tttttggatt tggtttataa ttgcagttgt agttgtgtgc
     3481 ataatttgca tggctatcga tgttgtaaga gaaaaatttg aaagacagat ttttaaaatt
     3541 aagagtgtaa agaacctgtg taaacttatg aatcatgtta taaatatata cccataatta
     3601 ataaatgagg agaaaagaag tgaaagttat atcattcgga gaattattat tgagacttgc
     3661 agcacccggt tattcaaagt tatttcaaag agatagtttg gagactacat tctgcggagg
     3721 ggaagctaat gtagcggtat ccttagcaat atttggatat caatcagaat ttataacaaa
     3781 gcttccggat tcagatgttg gatatgcggc agctaatgct ttgcgttatt ttggagtaaa
     3841 tgttgataat attatatttg gagagggacg catgggactg tattatttag aaaaaggagc
     3901 agctcagaga ccatctaaag taatttatga cagaaaattt tctgcaattt cgttagctga
     3961 tagtgatgaa tttaagtgga aggagatcct aaacgatgca aattggtttc attggacagg
     4021 gataaatcca gcattgtctg agaatctctt tgagacgtcc ttagatgcat gtcaggctgc
     4081 caaaaaaaga ggtataacaa tttcttgtga tttaaattat cgatccaagc tttggacatc
     4141 agaggaagca aaagaaaaga tggaacagat actaccattg gttgatattt gtatttgtaa
     4201 tgaagaagat gcagaaaaag tgctaggaat taaagctgag catacaaata ttaatagtgg
     4261 agaattaaat aaagatggct atgtgcaggt ggctagggag attcacaaga agtttggatg
     4321 taggtatgta gctacaactc tgcgtagaag ttattcggca agtagaaatg gttggagtgc
     4381 aatgttatac gaagcagaaa aagataaagc gtatttttcc acagaataca acatacaaat
     4441 tgttgatcgc gttggtggtg gagacagctt ttctgctggt ataatatatg cgttatgtga
     4501 aaatatgtcc ggacaaaagg ctattgaatt tgcgactgca tctagttgtt taaaacatac
     4561 tatagaaggt gattttaatc gaactacaat tgaggatgta tataatttaa tgaatagcgg
     4621 tggaaatggt cgcgtgttgc gttagtcaac atataaagat aaatcacagt aatttttatg
     4681 gtgattatct gtcttagtag tgattagaat aacgtgaaaa taaattgttg agcgtttata
     4741 ctgttttgaa aaataaattt aacatattga aaaatacaaa tatatacgta tattataaag
     4801 cgccgattgt aaaattaagc tagacaacta aaacagtcat ttgtgctaca ctcaaaatag
     4861 ttccgaccaa agaattataa ggagtgagtg caaataacct atacctatct tacaacggat
     4921 gaacttgtaa taatagagtc ttatttgaaa attaaccaat ctgttgctaa aactgcgcat
     4981 tgcttgaatc gttcaagtca aacgatccat aaagtatatc tgttcttcaa gcaaagaaaa
     5041 tcagccttag aata
//
LOCUS       DAFLWQ010000135         4933 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.139, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000135 DAFLWQ010000000
VERSION     DAFLWQ010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4933
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.139"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(535..1038)
                     /locus_tag="L1V16_002835"
     CDS             complement(535..1038)
                     /locus_tag="L1V16_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBN1277103.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            1397..2422
                     /locus_tag="L1V16_002836"
     CDS             1397..2422
                     /locus_tag="L1V16_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBN1277104.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            2745..3623
                     /locus_tag="L1V16_002837"
     CDS             2745..3623
                     /locus_tag="L1V16_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HBN1277105.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            4099..4215
                     /locus_tag="L1V16_002838"
     CDS             4099..4215
                     /locus_tag="L1V16_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBN1277106.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
BASE COUNT         1654 a          779 c          884 g         1616 t
ORIGIN      
        1 ggaataaaaa aataacatat ctcattttac acttttgtta ttttatactt aaaaaataac
       61 gacacagaaa ataccgtgtc tcagatttct ctactacttc taaaaactac tgtttttttc
      121 ctttgaaatg ccttcaaaaa gtaggatcag gcagaatata ctggcagaat caaggagaag
      181 ggagcctaaa taaggagaaa aaccatagaa aatataaagt aattacttat aaaacaagct
      241 ttttatagaa aaataatata cctgagtagg gtataaatta agacggaatt cctttctaga
      301 ttgagatatt gactaggaag aatgttaaga ttttaagcct ttaagctaaa aaaaaaccct
      361 ttttgttaaa taaggggaat atagcctgtc agtttcaaac tgcaagtcgt cctgctgcaa
      421 taatatagta gattagagat gaaaatagat ttttttaaac caatgactga ataaaaagac
      481 cgtcatagat acacattgga atgtgtctat tacggtcttt ttttacgaac gattttattg
      541 aagacggaca gttcgggtca aaaataaaaa agctacgatc agaaataaga ataaaatgta
      601 tcccaaaata atggctagac ggtctaactt atttgtcgat agatgtttgt ttagaagttg
      661 ataggcccat aaacctatca gtcctcctgt tgtattagtt atcaaatcag tgatgtccgc
      721 tacgccaata ccgaatagga attgaatcaa ttctgccaag aagcttacaa ggaaaataat
      781 ccctaatttt ttagaaaaag aaagtctctt gaaattgaca ttcaaaagca ccccaaaagg
      841 aaaaaagaca atcaagttat aagtggtctc acgtaatacc gtcgtatttt caaaagaaaa
      901 agtagaaaaa gggacgagat tgacattgct gtaagaataa gtgagaaatt gtggaagatt
      961 aaatgatagc ttgaataaaa tcaaccataa tagaaagaat aaataaatcc ctaataaaaa
     1021 ttttgataca taccgcatag acatctcctc catttaaaaa gtataccatc gaaaaccgct
     1081 gaaaaatcat aaaaaagtat gaagtttaag gaccaacgta gttatcgtac gaaaattaga
     1141 agcttttttt tgttgggaat ccggtttctt taacaaagct aagatagcga gttgcttgga
     1201 aaagttgcta tcttttttct gtcaaaacga ctcggaatgt tcgttttttg ttctaatttc
     1261 tccaagttgt ttactttttg atactaagtt tatgaaaaat caagaaatag ttgttatact
     1321 aggtaatgct gacaaacggg attggcattt catcttggtt cagctttttt tccaattact
     1381 aggaaggagg gatagattgt tcaagactta ttttcgtttc aataaaatac aagataatcc
     1441 ttttcgtatc atgaatctga tgctacttat ctttattgta ttatggttag gttacataaa
     1501 tcatgatttt ttgatttcaa gtttttcatc attagggatc tttacttttt tctattatca
     1561 aaacataccg atgaaatatt tgctgaaacg tatgtttctg atcggttgcg gactgttggt
     1621 tgctttcgtt ttggggatct tatcgactta tgttttatgg cttgaaccat ttgccgtagc
     1681 tttggttgct ttttccagca gattcgtgtt gcgattattc catatttcta aaccaggtgg
     1741 cttgtttttt gcgatgcttt ctgccatggg aacgagcatg cagctgccaa tcgctcaatt
     1801 accgatcgtc tcactttatt tttttatggg tgtcgttttt gccctgattg cggcagtgat
     1861 tacaaaatta ctggattcac ggcctgagca gacaattgaa aaagcaactt taaaagaaag
     1921 atttcacgaa gagcctttag tgatcattga ttctgttttc tacagcgctg ccttatttct
     1981 ttccgtttat gtcagtcacg gcttgaatct gcataatcct tattggttga ccttgtcatg
     2041 tgcatcgatt ttgctagcag aaaacttgga tgcgatgaag catcgacaag tccaatatct
     2101 gattggatcg atgggtgggt tatgtgtgtc ggcattcttg tcatttgtgc cgtttacgca
     2161 gttgcagacc atttttctga tcacttttct atatggaatc gcacaatttc tagttgctag
     2221 aaattatgca gttgctaata tttttcttaa tccgatggcg ttgatgctat ctacacttat
     2281 tcgtggagca tacttgattt ctttgatcga atatcgtttt ttagggatcg tcataggaag
     2341 tttcatcggt ttaggtgttg cgtgggtaat gacggttggt ttgcaacatt atttaacggt
     2401 tgttcgtcaa aaattagaat agaaggacaa atatatgtgc caaaagaggt tatgacaaga
     2461 tttttgtcac aacctctaat tcaaggtgtt caaaagccag attctcagca ttaagtcaaa
     2521 ttcacacaaa aatgtggaaa ggaactttca aaaaaatttt atatttattc tatcaaaaaa
     2581 ttttgtttat gatggtaact gaataaactt tcctgagatg gtcaatgctt tccttgaaag
     2641 tcttacagat attctttctt catagaaagt ttaagtttta tagttagtgt acaataaaag
     2701 tatgtttata ccatatggtg tccggataat cagtcattta aacaatgagg ttcaaagata
     2761 tgaaaagggg aaatttgatg aagaaaataa gcaatgaaat ccaaattctg gcagaaactt
     2821 taactcttcc caaagtcgtt atagagcaaa tgattgtaca agcaaaaaac atccttgatg
     2881 aggtgtttga gcaatatagt catgaactaa tggatcctaa taaagcaaag gcgactgcaa
     2941 agaaaataga caaagtctat gaagaggaac cttttgcagc attagctatt tatctatatg
     3001 cagcttctca aagttggaaa aaaatttatc aaccattgaa gattccaaga actatctatt
     3061 tggcaacaat gaatgctttt actagattta ttcatgaaca tttccaagta acaggaagct
     3121 atcgctttga ccgtggtttt tggatttggc attacactag tggcttgatc tttcggattg
     3181 gtgaattgga gtacgaaatg acatattttc cgaaagggta cacggatcta agattagaag
     3241 gaaagcagtg cctttctctt catattcctt ccgatgcaga tttatctcag aataagataa
     3301 gagatagtta cgaaagtgcc attcgttttt ttgaacttta ttttcctgat taccattacc
     3361 aagtgatgta cacagatact tggttactat cacccaatct tactaaatgg ttgaaaaaag
     3421 agtcaaaaat ctgtcttttt gcagccgatt atcgattatt atcagttgat gaacaggacg
     3481 atagtggagt cccttggatc tttggacgag tagatgccca aatacatgat tatccagaaa
     3541 gtacgagttt acagcgacaa gcaaaagagc aattgcttgc aggcgagcac attggctctg
     3601 gcttaggtat tcttacttca taagtttagt acttcgaaat agtttaaaag agcgtgagac
     3661 aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg aagcagaagc
     3721 aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt cgtgaatttc
     3781 ttcttatttc ttggagttaa acgcttctgt cccagcctct tttttagtgt tctatcgaac
     3841 acacagtacg ttcaataggt aaactagcta taacaataga tattaaagtt aacggacaag
     3901 agggcctttt ttaggtagct aaaacgtaat aatgaaaatt tatttccaga gataggagtc
     3961 aatcagctag tctgatcgac tgttttaaca agttgacttt cattttaact tttgatacca
     4021 tttaaaacac aaatcgtaat tgtttcgatt tgtgtttttt agcatgacta caatcaaaga
     4081 agaaagtggg tcgtccatat ggaaaaaaca gatatctcaa gtgcataccg ccgcttgaaa
     4141 agcccaaata tcaaaacacg aaaacgtgcg ctgaagatca tcaaagatgt gaaacggaat
     4201 agtgggaaaa ggtaagaaga aggaaactta attaaaaaaa tagccgaaaa acgtttttcg
     4261 gctattttca ataatcggtt tttgtgtaag gtttccgaaa gaactgctgt tgattttcca
     4321 tttttaacat atgataaatt ggtagaatct ttcttttcaa attgatacca ttccctaatt
     4381 ccagttatat agttaactac agaaccacaa agcacgtacg tttataaaag tattatctgt
     4441 agttattttt caattccctt tcaacctctt attttgacca gtagtattga tcactttacc
     4501 ttttaacacc tttgttcgtt tttgaaacat ttttagtcaa gaatggaaac gtaactacat
     4561 aatcaaaggt tttgcgaaat atttcatgaa atatttcatg tagaagcgag caatacggtt
     4621 gcaaataacc attatcgttt aataagcagt tacgaaagct cccaatatct ctaacgttca
     4681 gctcactcca tttcttttct tcaaaaaaat cagtgattcg tatctctttc tatttgtcga
     4741 aaaagttaac tttaaaaagt aacgccgaaa aaatatgcaa aaaaataaaa aagcagttac
     4801 tattgctaga ataacatcaa ggaataataa gttttggttt tcagataata gtcgataagt
     4861 tgtgtattgg aattttagat acagtaataa agtatttttc atgaaatttt gtgagaatca
     4921 ctattacaag tat
//
LOCUS       DAFLWQ010000136         4932 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.140, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000136 DAFLWQ010000000
VERSION     DAFLWQ010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4932
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.140"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            85..972
                     /locus_tag="L1V16_002839"
     CDS             85..972
                     /locus_tag="L1V16_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBN1277107.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="L1V16_002840"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="L1V16_002840"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBN1277108.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="L1V16_002841"
     CDS             2274..2720
                     /locus_tag="L1V16_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBN1277109.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="L1V16_002842"
     CDS             2993..4345
                     /locus_tag="L1V16_002842"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HBN1277110.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="L1V16_002843"
     CDS             4516..4803
                     /locus_tag="L1V16_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277111.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1695 a          813 c         1030 g         1394 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt tt
//
LOCUS       DAFLWQ010000137         4795 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.141, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000137 DAFLWQ010000000
VERSION     DAFLWQ010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4795
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.141"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(117..1079)
                     /locus_tag="L1V16_002844"
     CDS             complement(117..1079)
                     /locus_tag="L1V16_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1277112.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1081..2520)
                     /locus_tag="L1V16_002845"
     CDS             complement(1081..2520)
                     /locus_tag="L1V16_002845"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBN1277113.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2705..4651
                     /locus_tag="L1V16_002846"
     CDS             2705..4651
                     /locus_tag="L1V16_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HBN1277114.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
BASE COUNT         1535 a          810 c          781 g         1669 t
ORIGIN      
        1 tctaactttt gggggtcact acaagttgac aactcctttt tgtttacaaa tcaattggat
       61 atctacaaat tgtattttct aacgaatttt atagacatta aaaaattaat ttaacgttaa
      121 atacttcctc cagaaagtat tgagattggt aaaatataat ccttatttgt cttttcgcct
      181 ttaatttttt tcagaagaat atcaacaata agacttgcaa tttcatcaat tggttgtctt
      241 attgttgtca attgtgggaa aaatttctca ataaaagagg taccatcgta tccaataatt
      301 tttaaatctt ctgggatatt aagtttaagt tgatgagcaa ttttcatagt gagaatggct
      361 gttaaatcat cagaaacaaa aataccatct ggtttgtgat ttataatagt tgactttatt
      421 tccatttcac gacggatagt agacagatta ttaggaattt tgaaaatttt tccatttgga
      481 ttttgaaaag aaaaacctag tgcacgtaat tctgtgggag aatccgtgtt atcatttcct
      541 gtaatcataa tggtattttg acaaccattt ttttgtaaag tcttagctgc aagttttccc
      601 ccttcaaagt tatctgaaga aacaatggaa acattaggag ctaaatttct atcaaaagca
      661 acaataggtg ctctcacacg ctcataatca gcaattccaa gattatggct tgatgagatt
      721 atgccatcaa cttggttggc ttcaagcatt tcaatgtatt ctctctcttt agcaggatca
      781 ttttgactat tgcaaataat cgttttatat ccatgtttaa ataactctat ttcgagatac
      841 tcaatgagtt cagagtaaaa gatattacta atattaggaa aaataagacc aataagctga
      901 ggtgactttc cttgaagtcc acgtgctaaa ttatttggtt tataaccaag agttttcata
      961 gcttcatgaa ctttttgttt tgttttttct gataaatatc ccttattatt aatgacgcgt
     1021 gaaacggttg ttgggctaac tccagctaat tcagcgacat cagttaattt tgctaccatt
     1081 ttaatatttt aattcaaagt attttccagt aggttcgcct gatttgattt gaataccatt
     1141 ttggtgattt tcagggaata cacgactagt aaacactttt tctcctttat taataaaaat
     1201 ctcaatgatt gagttatcta caaaaatgtt agcagttgtt tctttagtat caattgagca
     1261 ttcacgaatc gtaccaaagt cagtggcata ttgaatgcct gctttgctgc gatctaaaat
     1321 aatttttcct tctttggtat ctacaatcaa gctaagtcca tttcctttac tatcagagaa
     1381 aagaagtaac tccgatttct gatttggagg aaaagttagt tcaagctcat aagtattatt
     1441 tgtttctgct tttgctgtaa attgttcaga actagcacgt aatgatgtaa tagcttctac
     1501 tggatattgg taaagtttac catcttttat tgaaagttct tttacaagac tcattgctcc
     1561 ctgataatca tacttatcag ttggataatc gatatcaggt agtccaatcc aactgacaat
     1621 cagagcacga ccatcaggag tattgaatcc ttgagtcgca tacgcttcaa atccataatc
     1681 aagattttga atttctgaag cgcccacaag ttttactttt tctatgtcaa gcgattgaca
     1741 gatcttaaaa gtattcggat agatattccc ataatttagc tcagatttat ccaacccttg
     1801 aggacaataa atgagaacag gttttttgtc tacaaatact agatttggac actcaatcat
     1861 gtattctgaa ccagtgccgc caaaatcaag gttgccaact tcctcccatg tttccacgtt
     1921 attgtcatcc gctttgtaaa gtttgataaa gcctgatttt tctaaatttt gtgctccaac
     1981 aatcgcatac aattgtcctt cataattaaa catttgtgga tcacgaaaat gatcagttac
     2041 atcagcaggt ttatgaataa gaacattctc acctttcgta atgttgtagt ctttatccat
     2101 ccatgctccg atttgaagtg tatcacgttc ccaattttca tttcgaacgt ttcctgtata
     2161 gagtaagaat agattcccct ctatttcata tgcagaaccg gaataagcgc cgtggctatc
     2221 tcgttttgtg tctggaagaa gttctgctcc tgttacatga aaatgaacta aatcatctga
     2281 ttcattgtgt acccattctt tcaacccatg agcagctcca aatggccaat tttgataaaa
     2341 aagcgtatat tttccgttaa aaaaagaaaa accattagga tcgtttaaca atcctgtttt
     2401 aggttcgata tgatagctag cacgccaagg tgatcgtttt acattatcct taattttatc
     2461 catctcatct ttagtccaat cagaataagc acgatatcgt atttctcgag gtaagttcat
     2521 attttactcc ttcaatttat ctttttacaa ctagtatggt aaacgttttc cgttgaaaaa
     2581 tcaatcattt catttaaaaa aataaactat atgacaaacg tttgacatat ttttaagata
     2641 tgctaaaata aatttgcatt tcagtgaacc gttttcacgt aaaaataaaa aaggagtgat
     2701 tcgaatgaat tacagtaaag tagcttccga cgtaatacaa gcggtcggaa aagataacct
     2761 tattgcagct gcacactgcg ctacacgtct tcgtctcgta ctaaaagatg acacgaaagt
     2821 gaatcaaaaa gctttagacg aaaatccaga tgtgaaaagc acatttaaaa ttgatggaca
     2881 atatcaagtg attatcggtg caggtgatgt taatttcgtt tatgacgaac ttatcaaaaa
     2941 aactggactt tcggaaattt caacagatga tttaaaacaa attgctagta aagataaaaa
     3001 attcaacccc attatggcat taattaaatt attatcagat atttttgttc caattatacc
     3061 tgcccttgtt gcaggtggtt tattaatggc attacaaaac tttttaacag ctgctggact
     3121 ttttggacca aaatcaattg aagaaatgta tcctgcgatt gaaggtattt cctcaatgat
     3181 ccaactgatg tccgctgcac cattcatgtt cttaccaatt ttagtaggta tttcagctgc
     3241 taaacgtttt ggagcaaacc aatttcttgg tgctgcaatt ggtatgatca tgacaacacc
     3301 agatcttggt ggctcaactg aatattggaa tatttttggt tatcatgttt cacaaacaaa
     3361 ctatgcttat caagttattc cagttttagc agctgtttgg atattatcta tattagaaaa
     3421 attctttcat aaaaaattgc catcatctat tgactttaca ttcacgccat tattatcagt
     3481 aatgattact ggatttttga ctttcacagt tattggccct gtaatgttat tgttgtctaa
     3541 tggaattaca gacattattg tttggctata taacactact ggatttattg gaatgggtat
     3601 ttttggagga acatattcac ttatagtcat gactggttta catcaatcat ttccagctat
     3661 tgaaactcaa ttactttcag cgtggacaaa tggtatcgga catggagact ttatctttgt
     3721 agttgcatct atggcaaacg ttgctcaagg tgctgcaaca tttgccattt ggttcttaac
     3781 taaaaattct aagacaaaaa gtcttgcttc ctctgcgggt gtctcagcac ttcttggaat
     3841 tacagagcct gccttgttcg gagttaactt aaaataccgc tttccattct tttgtgcttt
     3901 aattggttca ggaattgcta cagcagtagc aggattactt aaagtagttg ctgtttcact
     3961 tggttcagca ggtttcttgg gatttctttc aattaatgca acatctattc cattttacgt
     4021 attgtgtgaa ttgattagct ttgtagttgc ttttgcaatt acttacttct acggtaaaac
     4081 aaaagctgct ggtatcttta aagcagaaga aattgctgaa caaacaccag ttaattcttc
     4141 aaaagtagca acaacagatc caatatctac tgatgttgaa tcaacacaaa caaaagtttc
     4201 atcagaaaca attgttagtc ccatttctgg taaagtgatt agtctttctt cagtaaatga
     4261 tccagtcttt tcatcagaag ctatgggaaa agggattgcc attaaaccaa atggaaacac
     4321 ggtccattct ccagtagatg gtactattca actcacgttt gaaactggac atgcttatgg
     4381 tattaaatca aataatggtg ctgaagttct aattcatatt ggtattgata ctgtatcaat
     4441 gggaggaaaa ggatttacac aaaaagttac tactaatcaa aaagttagaa aaggcgatat
     4501 tcttggagca tttgaccgtt caatgattga gaaagaaggt cttgatgata caacaatgat
     4561 tattgtgacc aatacttcgg attattcaga agtaaatata gtagctgaaa atacagtcac
     4621 tgagggtact gatttacttg aaatcaaata aatatatttc cctgagtaaa gatggaattt
     4681 tctttccaaa atcaaataat atagattaat caaatatttg agaataacat tttatttaat
     4741 cttttcatat atcaattgta tgaaaaatta ttagaatttt aaaaaatgat aaaaa
//
LOCUS       DAFLWQ010000138         4737 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.142, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000138 DAFLWQ010000000
VERSION     DAFLWQ010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4737
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.142"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            64..297
                     /locus_tag="L1V16_002847"
     CDS             64..297
                     /locus_tag="L1V16_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277115.1"
                     /translation="MDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVFVYLVCSYL
                     LKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(456..578)
                     /locus_tag="L1V16_002848"
     CDS             complement(456..578)
                     /locus_tag="L1V16_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HBN1277116.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            768..992
                     /locus_tag="L1V16_002849"
     CDS             768..992
                     /locus_tag="L1V16_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277117.1"
                     /translation="MIKTQPLLVRFTLRTSHEPINCVVANIEIADKLLILEEGKYTIS
                     VTGHFNKRKQLVIESMQIRNPDHFTRSMSI"
     gene            1435..1641
                     /locus_tag="L1V16_002850"
     CDS             1435..1641
                     /locus_tag="L1V16_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBN1277118.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            1641..1892
                     /locus_tag="L1V16_002851"
     CDS             1641..1892
                     /locus_tag="L1V16_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277119.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEVLLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENLETYENEYWLTKLEN"
     gene            1908..2063
                     /locus_tag="L1V16_002852"
     CDS             1908..2063
                     /locus_tag="L1V16_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277120.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKEKLSV
                     AVEEMIE"
     gene            2073..2345
                     /locus_tag="L1V16_002853"
     CDS             2073..2345
                     /locus_tag="L1V16_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277121.1"
                     /translation="MNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQ
                     ALELTYAKFIETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            2790..2969
                     /locus_tag="L1V16_002854"
     CDS             2790..2969
                     /locus_tag="L1V16_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277122.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDVPALKK"
     gene            3028..3384
                     /locus_tag="L1V16_002855"
     CDS             3028..3384
                     /locus_tag="L1V16_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277123.1"
                     /translation="MLKTKKNSYKLKLSILSIICLLGMIISGHLYRVAYTQFIEYKVH
                     SLGLAGDRYVEYVHYSLKCSSYILLWLIFSLFELLNLIAISSYHLDKLNTKSSRYNEV
                     FKENVKLESDLNKLKK"
     gene            complement(4353..>4737)
                     /locus_tag="L1V16_002856"
     CDS             complement(4353..>4737)
                     /locus_tag="L1V16_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1277124.1"
                     /translation="LKPEGRKAVDIENSINEWLQSVPKNLFKSITFDCGKEFSNWKSI
                     SNTNDIDIYFADPGTPSQRGLNEHSNGLLRKDGLPKEMEFNQVNQGFISSVASKRNHI
                     PRKSLNYQTPLEVFLSYVNGKFCLA"
BASE COUNT         1641 a          740 c          911 g         1445 t
ORIGIN      
        1 tgatgatcta ccgttttagt ttgagaaaga aggagtaagc atggcaaaaa aattagtctg
       61 acgatggatc tattgatacc cgtaattgca tttatagacg ggatttcttt gggcgtcact
      121 gaaaatcctt tggtaaatag aattgcgaaa ggatcactat ttcttgtatt cgtgtatctt
      181 gtctgttctt atcttttaaa aagagcagga aaggataatt ccttttggcg attgactaaa
      241 gtcacagtag cagcgacagc tgttatactt acggctattc taccgcttta tatgtagagt
      301 taacgggaaa tcgttgaact tcttgcgaaa tattgctata atgaacatga aaaagaggag
      361 ttgcgctaac aacccctcat taacagcacc gattaaagaa cggtggcaga atattagtta
      421 tttggaaata accgctgacc tgctaaagta gacggttatt tctttttgtc atttttaagc
      481 atatttacaa tcaaactaat caaagcaatg gtaaacatac caaaaccaag aatggtttga
      541 attgtctcat atgcggacaa aaggcttact cctttcatag attttagcac ttacattcat
      601 aagcaccacc acctttccag aagtcgccac cgtcttcaaa ctttactgtc ttgactatta
      661 tagcatatct aaaatcgaat aaaaattctc aattttagct gtttttgcta taattttagc
      721 gaggtgatcg tgatggaaca atatattggt ttactcgata aattagggtg atcaagacac
      781 agccattgct tgtgcgattt acattacgca cgagtcatga accaatcaat tgtgtagtgg
      841 ccaatataga aatagcggat aaattgctga ttttggaaga aggcaagtat actatttcag
      901 tgacaggtca cttcaataaa cgaaagcaac tagtcattga atcaatgcaa attagaaacc
      961 ctgatcattt tacgcgatcg atgagcatat aaaagaagag ctgcagtcct aaatgaggat
     1021 tgtagctctt tttgttttac atagaaacag taaaaatgaa aaggcctgtt taggaaggca
     1081 caagcgcctt ctcaattgaa agacctttct ctcactccaa ccgccaccgc cgttcgagaa
     1141 gaaaggaagt gaacgctacg cgttcactaa gataaagggt cttgcatagc aagacaaaat
     1201 agaaaaaatt tcctctcacc aaaaggttcg ctcctgttcg ttatctcttt attgatttgt
     1261 cagaccggca acaagttgcc ttttatcacc aaaaagcgac aaggacaagg gtaaatggca
     1321 cgctgcgcgc ccttgtcttg tcgcttttcg ttgattcatt ctggccaaca aatcaataaa
     1381 gaaagaacta acgaaaggaa gtaaaacctt tcctaagagg aggcagaatc aatcatgcga
     1441 aagaaatttg attattgggg tgttcccttc agcgaattat tcccaaacta tcatgcacca
     1501 catactgtcg aatgcgattg tggagaaaga gcgaaatgta tcaaaagcta ttgtttgtat
     1561 caatgtccaa catgcgggaa aaaatatacc ttgtcttatg gcgattatat tttaattgat
     1621 gagaaaggaa agaaacgctg atgaaaacac aacacaaatt attgactgta aaagaagtcg
     1681 ttcaaatttt ggtggacaaa gaagtcattt ctgaaaaagt agcagaagtt ttacttattc
     1741 cgcggtactg gacgatagaa acccctttag tagaggatgc accgactatg ctatttgaag
     1801 acctagtgaa gattgcagga tatgaactgc attatcaaga aaacttggaa acttatgaaa
     1861 acgaatattg gttaaccaaa ttagagaact aaaaaggaga aaaaaatatg gctcaaaatt
     1921 actatgacga atttgtcaaa ttacctttgg ataaaatggc acaaaaaatg gaggatatga
     1981 cgttcctata caacgaaaca cgtgttccaa aaaaacatta taaagaaaaa ttgtcggtag
     2041 ctgtggaaga aatgattgaa taaggtgtcg aaatgaatct tattgcgacg tactatcgaa
     2101 cactggaaga actgaaaaag caaaatgcaa aatggttttt ccaagcctta ctatgcttgg
     2161 aagtaggtgt caaaccaagc actattaaac cttctgaata ccaagcttta gaactaacgt
     2221 atgcgaaatt tatcgaaacg aaaaaagcca agactgtttc aagtgaatgg ttagattatt
     2281 ttgaaaatat caataagtat ggcgcatatt acaccatgaa aaaggaagac aacgaaaatg
     2341 aataaggtga tttatcaact aacaacggat tccatatcaa cgatttgaaa gaaaaaaagg
     2401 tcaataatca tttataccga aaagtgagaa tgtgtgaaac aaggacaaaa aaagcctagt
     2461 aactaaggaa atggttctta tttcgcacca atcgctccaa ccgcccccgc cgcttaggtg
     2521 gtgcgaaata aacgggcaaa gcccgataac ttaagagaaa gaaggtgatc catttgaaca
     2581 agattattcc cttattgtta gtactgtttg ttggcgaaat acttatgcga gatagtgcag
     2641 ctgtacagtt aaacctcgct gtatttttgg taatactggt gttttgtttg atcttttggc
     2701 ggtttgtatt agtcctcgtg agtctactat tcaagatgat tgcagccata tttttcatag
     2761 ggttatttcg atgaaaggag tgagtaccaa tgccaattgc aataggaaat aaacggttac
     2821 ccgtgacatt agatgaaaag agacaaaaag aattgcagca actaaagcag aagtatggca
     2881 aaagtgaatc taagattatg tgtattgcgt tagatctatt gatcgcgcaa gaaaaagcag
     2941 gatttgatgt accagcgcta aaaaagtgac gtcacttttt aatttgatct atataagtga
     3001 tatcactttt accaaggagg gaattaaatg ttaaaaacta aaaagaattc gtacaaatta
     3061 aagcttagta tactatctat tatttgtctt ttaggcatga taattagtgg tcatttgtat
     3121 agagtggcat atacgcagtt tattgagtac aaggttcact ctttaggatt agctggggat
     3181 cgatacgttg aatatgtcca ttattcatta aaatgttctt catatattct tctttggctt
     3241 attttttcat tgtttgaatt gctaaattta atagcaatat cttcatatca cttagataag
     3301 ctaaatacca aatctagccg ttataacgaa gtgtttaagg aaaatgtgaa gttagaaagt
     3361 gacttaaaca agctaaaaaa ataaaaagaa gaaaacataa gttaactaaa attattttat
     3421 taagaatgat ggaatataag gataaggtta ccaacataac gatcattact tctctgatat
     3481 gctatggact tctatcaatc agtattttgt ctatagatta tggagtaact atactgcaag
     3541 ccttagtttt ggctatgcct atgtatctat ctttgtttat catgcatgaa atatataagc
     3601 tatttgtttt atcaaaaaat gtagaaatac gggtaaatat tttggtgaat agttatcaaa
     3661 aagaactcaa agaaagaaga cggtggcggt atttattgaa aggatgaaaa agtaggattt
     3721 gacatactgg tattcagaaa gtgccgtcac ttttaaaaca atggaaaagg tggagataag
     3781 atgaagaaaa aacaaactaa actatcatta gcagatattt aacacagtta accgcaactg
     3841 aagatggtgt tgttgaattt gaacaatctg aaattgcggt agtagatgat cgttacctta
     3901 aaatgcctta cttctttgac caagcaaagg tcatttgcct ttgtcactac gatggggtac
     3961 gtgattttag gcgttaaaaa gtagtgatta tatcaacttt acgagtaaat ataaatttag
     4021 acatgaaact gaattatcca atggaaaatc atggtttata atctagaaaa attatagtaa
     4081 tgattggatt atatatattc tttcgtattt tcgtacaact gtagcttgtc aaaattgaga
     4141 aatttaaccg attaggtact ttacatcgtt atttgggtaa tttctaaaac atgaagctta
     4201 ccaacgaata aactgagact atcttattaa ttgatcaata taagaaaata tctttgagga
     4261 gatgatgtac tatgttttcg tctatccacg attggttagg tggtcttttc ggcggtggag
     4321 gtaaaggttt ttaataaata ttatttgtca aattaagcga gacaaaactt tccatttacg
     4381 taactcaaaa aaacttctaa tggtgtttgg taatttagtg attttctagg gatatggttt
     4441 cttttggacg caacggatga gatgaatcct tgattgactt ggttgaattc catttctttt
     4501 ggtagtccat cttttcggag gagtccgttt gaatgttcat ttaatccccg ttgggaaggc
     4561 gttcctgggt ctgcgaaata aatatcaata tcattcgtat tactaatact tttccaatta
     4621 gagaattctt ttccacaatc aaaggtaatt gatttgaaaa gatttttggg tacggattga
     4681 agccattcat taatcgaatt ttcaatatca actgccttac ggccttctgg tttcaag
//
LOCUS       DAFLWQ010000139         4593 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.143, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000139 DAFLWQ010000000
VERSION     DAFLWQ010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.143"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(52..522)
                     /locus_tag="L1V16_002857"
     CDS             complement(52..522)
                     /locus_tag="L1V16_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HBN1277125.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(681..1139)
                     /locus_tag="L1V16_002858"
     CDS             complement(681..1139)
                     /locus_tag="L1V16_002858"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBN1277126.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1310..2455)
                     /locus_tag="L1V16_002859"
     CDS             complement(1310..2455)
                     /locus_tag="L1V16_002859"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HBN1277127.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2468..3385)
                     /locus_tag="L1V16_002860"
     CDS             complement(2468..3385)
                     /locus_tag="L1V16_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBN1277128.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3813..4376
                     /gene="efp"
                     /locus_tag="L1V16_002861"
     CDS             3813..4376
                     /gene="efp"
                     /locus_tag="L1V16_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBN1277129.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
BASE COUNT         1436 a          838 c          871 g         1448 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tcttttttta tttttattaa gttaaagaac
       61 ggattcaatt gcagcggtca ttttcaatgg agaagtttgt ggtgcaaatc gttcgattac
      121 tttgccattt ctatcaatca aaaatttagt aaaattccat tttattgctt tagtgacagt
      181 accaggagct tcatttttaa gataagtaaa aagaggatct gtattttctc catttacgtc
      241 aatcaattga tgcataggga aggtaacgcc ataagtggtt ttacaagctt ctgctgcttc
      301 agtcgctgaa tctagctctt gtttaaattg attggaagga aagcctaaga taaccagacc
      361 ttgtgtctga taagcttggt aaagttcttc taattgttta aattgaggtg ctagaccgca
      421 ttttgttgca gtgttaacaa tgattatcgg tttgcctgca tattttttca atgaatagac
      481 agtgccgtct tctaaagtag tttcaaaatt ataaatagac ataaagtttt ctcctttcta
      541 ttttatataa taaaaagagc gctaaactga aaactagcta tttgttttcc cgtttagaac
      601 tcttttcaga caataaatat ttaataaaat acgaagataa gatagctata ttgcttctca
      661 tctttacgtt cttttagaaa ctatgcttct acttcagacc attcatcgcg ttttgctaaa
      721 aattcacgag ccaaagcttg tgcaccttct agtgtatggc tggcagccca gccacattgt
      781 gtttcattgc ttgcaggtac ttcagtagct tcaagaacat ctttcattgt tgcttcaaga
      841 acatctaaaa tgtcttcgta gctttcatga ttcaatacag tcaagtaaaa gcctgtttgg
      901 catcccattg gagaccagtc tacgatgtaa tctgcgtgat tgcggattag ttcggcagtc
      961 aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt ctttatttgg ttgtttaaag
     1021 cggacgtcgt atttaatgat gacatcgcca tgcgcacccg tttttcgatc agctacacgt
     1081 acataaggtg ctttgacttt tgtatggtca agattaaaac tttcgacatt cattctcatt
     1141 tgtaagactc ctatctgttt gttcattcgt tttgatgctt ttcactaaag aattatttag
     1201 tgaaatttac aaaaacgtct ttctacttga ttctaacact tatcgtttcc aaggtgtagc
     1261 aatctgaaat attttttaga tttttctgct aagtcgttta ttgggacttc tagttcttga
     1321 ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg accatactca attcctacag
     1381 aaagacggat caagccgtcc tttatgccag cctcttctcg tttttctttt ggaatagacg
     1441 catgagtcat gacagaagga atttccacta aactttctac gccacctaaa ctttctgcta
     1501 aagtaaatag ttggagtgat tcaacaaatg gaatagcaga ttcttcattt tttaaagtaa
     1561 aagaaatcat tccgctaaag ccgctcatct gctgcttagc aactccatgg agttcatgat
     1621 cgggtaatcc tggatagtag accttttcta ctgctggatg agaaaataga aaatcagcta
     1681 ccacaaaagc atttttttga tgttcctcca tacgaacact tagtgtcttg attccgcgct
     1741 gaagtaacca gctatcttgg ggaccaagta cggctccgat agcattttgg taaaatccga
     1801 tctgatcggc tagatcttta tggttagaag tcactaaacc agctactaca tcgctgtgtc
     1861 cgcctagata tttggtaccg ctatggacaa cgatatcaga accgagatct aaaggtcttt
     1921 gaaaataagg agtagcaaat gtattgtcag caataactat caatccatgt tgatgagcca
     1981 gagtggcact tttttctaaa tcagtaatct ttagaagcgg attgctaggt gtttcaagat
     2041 aaagtgcttt tgtattgggt ttgatggatt gttctatttt atcaagatta ctcgtatcta
     2101 tgatcgtgta ctcgagacca tttttagtaa gaactttgtc aaatagacgg aatgttcctc
     2161 catagacatc atctcctaat aagatatgat cgccagcttg aaaaagagaa aaaacggcat
     2221 gaatcccaga aagaccagaa gaaaaagcga atcctcgaac accgccttcc aaatcagcaa
     2281 tcagttcttc caatgcaaaa cgagtaggat taccagatct tgaatattca tattgtttag
     2341 gctggccgac gccatcttgc cgataagtgg atgtttgata aataggtaca ctgacagctc
     2401 ctgttgtggg atcttcactg atgcctccgt ggatcaattt tgtttgaatg tgcatgtttc
     2461 tttcctccta taagtaaatg ttttttgata aatagcggtc tgctgcgtct ggaaaaatcg
     2521 taacgacacg atgaccaggt ggtaaacgac gaatttctct taatgctgct gcaaaagccg
     2581 caccactcga acttccaact aatagtcctt gttctcgtgc taactgccta gtatagttaa
     2641 acccttctac atcagagatt gtctcgatct gattgattga aaggggagaa agaaacggcg
     2701 gaatgaattc tacaccgata ccctcaattt cgtgaggggc tggatcacca ccatttaaca
     2761 cagagccctc tggttctaca ccgattattc gaatgtcggg atatttttct ttcaaaaagg
     2821 tagaagttcc agcaaaggtt ccaccactcc caattcctgc tacaaaacta tggatatttt
     2881 ctttgatttc atgaaagatt tctggcccta acgtatgata gtaagcagca ggattatctt
     2941 tattttcaaa ttgaagaggc agatagctgt ttgatatctc ctctgcaagt tttttacttt
     3001 tgctgatggc accgatgatt ccttgctcac taggagaatg gatgatcttt gctcccaatg
     3061 ctttcatcaa ttgttgtttt tctaagctaa acttctctgg aacaacaaaa accgttctta
     3121 atttgtatgt gagtgcggcc agagcgatcc caattcctgt atttccggca gttggttcga
     3181 tgatcgtcgt tttttcattg atttttcctt gggcaaatcc ttctttgatc aaataactgc
     3241 ccaatctatc tttgatactt cctccaggat ttaaatattc tagttttgca taaatagcag
     3301 aacctttagg catagaatag tgctgattgt caaagcgata aagcggtgtg gaaccaatag
     3361 cttctgtaat tgtcgagata atcatgtggg cctcctaaaa aaagataata aaaaaaggag
     3421 ctgactatta aatcagctcc ttgaaagaca tagagaaaaa ttgagtagat aaaaagataa
     3481 gttacctggt actcattcta tgaagggcaa ttaatagaca tgacaaatag tatgctgctt
     3541 ttatgcacca tacaacagca acgattcaat tgtttttggt tgctgactgt catgtgtatc
     3601 cctccaagta aaatttttat taacgatagc atgaaaaaaa ataaaagtca aaggcttgaa
     3661 agaaaaaaat atttcgatag catcgtttac ccgtgtttat ttttctgaca aataggcatg
     3721 agaccttaaa agatagagaa tactctagtt ttctggccgg ttgtctgata caataaagtt
     3781 gattatgata aagaaaagaa ggagcaaaaa taatgatctc agcaagtgat ttaagagccg
     3841 gtatgacttt cgtacaagac ggcaaactga ttaaagttct ggatgcaagc caccataaac
     3901 ctggtaaagg aaatacagtt atgcgtatga aactgaaaga tgtccgttca ggtgcaacat
     3961 acgacacaac gttcagacca gaagaaaaat ttgaaaaagc acatatcgac acaaaacctg
     4021 tacaatattt gtacacgatg gatgatacag ctttcttcat ggatttggaa acatatgagc
     4081 aatatgaaat tcctgtagaa acagtagaag aagaaatgaa atatatccta gaaaacatgg
     4141 aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt tcaattacca acaactgtcg
     4201 tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc aacagtcact ggttcaggta
     4261 agccagcgac aatggaaact ggcttagtag tcaatgttcc tgacttcatc gaaacagatg
     4321 aattgttgga aatcaataca gcagaaggtt cttatgtaaa acgtgcgtca aaataattcg
     4381 ctaacggatt gataagaatt tgaaaacaga gcttgacctc ttgaaaggca gatcatcgga
     4441 tctgcctttc aagaggtttt ttgtggaatc agcaaattga aaaataaaaa agtatttgat
     4501 tttatttata ttttgaaaga tgaatggcaa aagctagaga aagaaaaaac tgcacttatt
     4561 tatgaagaaa ttgaaatgat tcataaaatt gaa
//
LOCUS       DAFLWQ010000140         4587 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.144, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000140 DAFLWQ010000000
VERSION     DAFLWQ010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.144"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            186..2855
                     /locus_tag="L1V16_002862"
     CDS             186..2855
                     /locus_tag="L1V16_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HBN1277130.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2946..3566)
                     /locus_tag="L1V16_002863"
     CDS             complement(2946..3566)
                     /locus_tag="L1V16_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1277131.1"
                     /translation="MFLINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKA
                     MHMVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPG
                     IEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTI
                     IKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3680..4219
                     /locus_tag="L1V16_002864"
     CDS             3680..4219
                     /locus_tag="L1V16_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277132.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4216..4554
                     /locus_tag="L1V16_002865"
     CDS             4216..4554
                     /locus_tag="L1V16_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HBN1277133.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1419 a          790 c          860 g         1518 t
ORIGIN      
        1 atttttaagg gtgggacttt tgattcctac cctttttttg cgtttatttt tgttatacga
       61 acaaattatg aagttattta ttctaaattt tatttttttg tgaaaattag actcttttta
      121 agcagagaaa aacaaggata tgataaactg aatacaactt catagaaatt tggtggaaaa
      181 taaatatgaa aaaaaattta aagtcattct ttagagaaaa cggacgctac gcagcagcta
      241 gtttcctgat tccgtttttg attttagcac ttgtttatct aagtatcggg atctatcctg
      301 gaagcagcag aagtattttg gcaagtgatg ccttttcaca gttttctaat tttcatgcca
      361 gcttccgaaa tgttcttctt ggaaagcaaa gtatttttta tacatggaat gcttctctag
      421 gattgaatta tttatcttta atttcttact atctaggcgg gatcttcacg ccactggtgt
      481 tcttttttcc aaaccagatg atgccagatg cactgtatgt tctgactttg cttaaggtcg
      541 gctgtgccgg attggctttt tggtttcttg cacgtacgtt caagattcct cgctgggggc
      601 atgttgcact tagcgtcagt tacgcattga tctcatttat cactgcacat tcggagatca
      661 tcatgtggct ggatgcattt gtttatcttc cattagtgat tttggggatt catcgtgtta
      721 tggatcttaa acggccgaaa cttttattta tcagttattt actcttgttt ttatccagtt
      781 tttatatggg ttttatgatt ggcgtatttt ctttcttata ttttatcgcc cgtctattga
      841 caaactggtc agaatataaa aaaacgattg ttccttatgg tatcacttct ttactggcag
      901 gcggcgcttc aatgatcatt gtattgccag cagtgctgga tcttcggtca aatggcgagg
      961 cactgagtca gatcactacg ttgaaaacag aagcgacttc ttatctggat ctaatcatga
     1021 aaaatatgat tggtgtttat gacacgacaa aatacggatc gattccgttc gtttacgcag
     1081 gtctgctacc attagtcctc tgtctgtttt attttgccag tcggaaagta ccgttgaaaa
     1141 ataaattttt gtacggcagt cttttcgcca tacttatcgc aagtttctat cttgttccat
     1201 tgaatttgtt ctggcatggt atgcatgcac cgaatatgtt tttattccgt tatgcctatc
     1261 tgttctcttt cttagtgctc ctgcttgcag gaaaaggatg ggaaaagata gaacaagacg
     1321 atcgtgggct gttgttagga atcattttgg tcgtagctgc tctctttgcg gtggcatggg
     1381 gcatcaaacc tgaaggaagc tacacctatg tgacgatgac ttcctttgta ttgacagtgg
     1441 ttttcttagg gatttatgct tttgctgtgg gattttatca gcataaaaaa ctttcattca
     1501 atcatctgag tatattgtta ttattgatca tgtctgctga agcactggtc aatacgaaca
     1561 gtatgatcca tggcattctt gatgattgga attatgcttc ccgcagttta tatactgatc
     1621 cttatcctga cttgaaagct cttgtaaatg aaacaaaaaa agattccgac tcgttttacc
     1681 gcttggaaaa tctggatcca gtatctgcaa acgattcgat caactatggt tacagtggta
     1741 tcagtttgtt ttcttctata agaaatcgta attcttcctc ttacctggat aaattaggtt
     1801 tccgttcaag agggacaaat ttgaatatcc gttataacaa taatactttg ctaatggatg
     1861 ggtttacagg aatcaaatat aacatttcta aaaacgaaag cacgttcagt aaatatggct
     1921 tccgccaagc tggtcaaagt ggcgactata cactgtatca gaatgtcaat gcattgccac
     1981 tagcatttac tgcaccgttg tccgttaatg atgttgagca gccagtgaca gataatttga
     2041 ccagtcagac aaacttgatc aatacattgt ctggtttaaa tgaacagtat tttacattct
     2101 atacacctac tttgaagaat cagttgaata cgacgatcac aaagacaacg actggcgtca
     2161 cttactcaga aacagcagat aaccagccaa aagagctcac ttgggaagtc catgtgcctg
     2221 caaatacaca agcttactta agtttgttcc caaccaattt tgcacaatta gaaagttcta
     2281 gtgcgacgat cactgtcaat ggtacatcgc gaaaaacgca aatcaacatt tctggtcaat
     2341 actatgatct tggctattat cctcaagaga caacagtgac atttactgca agtttttatg
     2401 gaacgaaaga agtaagtttc atggagccta aagtcgttgg tctagatgtt gtagcctatc
     2461 aagccgcaat gaatcagatc aaagaaaaag gtgtcgaaat ggaagccact ggcagaaaag
     2521 cttctgggac tgtaaatacc gctgaagatt ccatgttggt gacaactatt ccttatgaca
     2581 aaggatggaa agctaaaatt gatgggaaac cagtcaaggt cagcaatttc aaagacgcat
     2641 tcttgatgat aaaagttcca gcaggtaaac atactgtcac tttcagttac ttgcctgaag
     2701 gatttacgat aggtgcaatc ctttttgtcc tatgtattgc attgtttatt ctttatgtct
     2761 ggtaccttga ccgcaatcgc cccttttatg gcacgattga tccagcaata gaagaaaaac
     2821 cgcgaaatac acacagaaga agacgaagaa aataaagaaa cgatggaatc tgtgtcactc
     2881 ttctatttaa atggcaaaaa tttcaatctt taaatgacaa aaaccacctg atttttggtg
     2941 gttttttata tacctatgac taaactatct cttgctgctt cgacaacttc tacagtgatc
     3001 ttatccattt gattgattct taaaatccga tcaatctgcg caaataaacg atgaataagc
     3061 ctaaaatttc cttttgtgat cttaatgata gttgtgatag cctcataatc agaaaaatct
     3121 tctagcttga tatcaattcc taaatctgcc catttgtatt ccaaaatatg atgtgtttcg
     3181 tccttactaa ggttatcaaa ttcatgtgca aatcctatgc gagagtaaag ctgcggataa
     3241 cgagacaatc ttttttcaat accaggcata ccgataagaa ccattgccag atcatttcta
     3301 tcgtaaatat ctcttagctg ttctaaatgc tgaagcttta aacgatcaat ttcatcgaca
     3361 ataattaagt caattgcttc ataggtttta ggcacaggag gatcttcttg attgtatttt
     3421 agtaccatat gcattgcttt agtcagacct attctactag ttattgtgtt aatatccgaa
     3481 ctgacacgag acatcttttc agctggtaca gtataaaaaa ctttatttac acttaatatt
     3541 tcatctgttg catttatcaa gaacaagaaa aagtctgaat attcaaaaaa aataacggtg
     3601 tacattttta aaaggagatg tataatcgag atttagaaag cgttttcctc aaaatttaat
     3661 gaattaggaa gtgattacta tgaaaaaatt atttagcgca ctttttattc tgttatttgg
     3721 ctttattggt attgggactt ctggaaatat agttaaagct agcacgatgg ttgaacaaac
     3781 aagtgaaatg gcaaaaactt ttagtcaatt aacaccagaa gaacaaagtt acttcaaatc
     3841 caaaggattt agtgataaag atacttttta cactcaaaag atagagcctc aagatccgaa
     3901 aacacgtttt tctgcaaatg tattgcggtt aaccgcatct actaaaaaaa ttactaatac
     3961 gcaggggcgg acagaatata ttataacaag tcccaattcg gcgatgtatc gtatttctac
     4021 acgcttgagt ttaggtagtg caaaatcata tactcaaaca gtaaatctag ctaattctta
     4081 tggttatggt ggaggaatgt attttacatt tactgggaaa agacaatatt acagtgtaaa
     4141 attagctatg caagtttata atacatttgg tgtagggtca gtctcttgca ctgcgggagg
     4201 attgacaata ggaaaatgat aatttcttac tatgtcttaa atagaagtga tgatgaagga
     4261 ctcttcgttt ttcaatcatt acatgaggat acgatgctaa aagagtttta taatcggatt
     4321 aagaataaac agatagaaac aaatttatat tttttaagtg actctatctt gccttttatt
     4381 agcaacccta aaattcttaa cttgttgcag acaaaagatt tgaaaagttt accgattatt
     4441 gtcattgatg aggaaattgt aaaatatggc gcttatctaa gcgtagaaga attagaaaaa
     4501 ttaactaaca ttggaatgag tattcaggag gataatgggg tacatggaac atagaatgaa
     4561 tatgcacagt tgagaacgga atttgac
//
LOCUS       DAFLWQ010000141         4467 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.146, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000141 DAFLWQ010000000
VERSION     DAFLWQ010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.146"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            110..964
                     /locus_tag="L1V16_002866"
     CDS             110..964
                     /locus_tag="L1V16_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBN1277134.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1061..3310
                     /locus_tag="L1V16_002867"
     CDS             1061..3310
                     /locus_tag="L1V16_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBN1277135.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3313..>4467
                     /locus_tag="L1V16_002868"
     CDS             3313..>4467
                     /locus_tag="L1V16_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1277136.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1574 a          632 c          814 g         1447 t
ORIGIN      
        1 aactttgaga tattctttag gatattaaaa ttaactagca ccacgggtta tgtaataata
       61 taaacataat aaaacaaaaa ttatccaaat ctaacatagg agggtggata tggaaaattc
      121 tatatattta gtaacagaac ctaacactca gctgaaagat tgttacttta atttttgtgg
      181 gtattcaaaa acagaaccta gacatagttt tggaccagct attcgagaac aatacttaat
      241 acacatagtg ctagaaggtg aaggctatta ttcaattaat gatcaaaaat attttctgaa
      301 gaaaggccaa ggatttgtta tcccaccagg agtatctact ttttatcaag cagatgaaaa
      361 aaatccgtgg tcatatgtat ggttgggttt aagtggcaat cttgtagaat actatctaaa
      421 agaaattggt gttggaaaga atcatcttac ctttaaagtc gaaaatttaa attcatttaa
      481 aggattaatt tttgaaactt tatcgtatga tcaggacaat ctagtcagtg aattgtccag
      541 acaaaaacaa gtttataaat ttttagaact cctcttaaat tcagctagtt atctgaacga
      601 agggataatt actaaaaaga tgaatccttt tgttcgtcaa acaattgaaa taatacgtga
      661 gaatgcgtat caaaaattat ctgttaaaga tattgctgtc agtctatcga tacacgaaaa
      721 ttatttatca cgattgttta agaatgatat gggaatatca ataaaagagt atattagtga
      781 aatcaaaatt tctattgcaa acgatctgtt atcatcaact gaatattcaa tccagcaaat
      841 cagtgacaag ataggattct caacagtaca atctttttct aaagccttta agaaagcaaa
      901 tggtgtttca ccgggagtat atcgaaaacg tagattaggt ctaggaatca ttaatggtga
      961 ataaactaaa catttgattt tgataaatat tcgttacttt aaacgcttac tatttatgtg
     1021 agcgtttttt ataatgcaat aaagaaacgg aggagagctt atgtataagg ataatgaaat
     1081 gaatattatt tatcgatcag aaaaccaaca atttcatttg tttaatcagg agataagtta
     1141 catttttaag atatcggaag atggtaaatt attgcattta tattatggtg agaacttacc
     1201 agataatgac tatagtcatc taattgagat gcatcatcgg cctatgacaa cctatagaaa
     1261 tgaaaacgat ttgctatatt cgttagagca cttaaaacaa gaatttcctg aatatggtac
     1321 aacagatttt agacatcctg ctatttcatt actacagaaa aatggctctc gcttatcaga
     1381 ttttgtctat caagggtacg aagtggaaga aggaaaacct aaactagaag gtttacctgc
     1441 tacctatgtt gataataatg atgaaagcaa aacattgaaa gtttatattt tagattcagt
     1501 tacaaatgtt caagtagaat tattatatac aatttataga gattatcctg ttattactcg
     1561 tagcgcgcga gttatgaata aaggaaaaga tattcaaata atcgagaata ttagcagttt
     1621 atcattggat ttacccgatg caaattatga atggcaacaa ttatctggtg cttggggtag
     1681 agaaagaact attaagtcgc gtactttaca acaaggaatt caatcaatcg aatctactcg
     1741 aggtatttca agccatcagc ataacccatt tgttacttta aaaagaaaaa atactgatga
     1801 aaatcaagga gaagctattg gtgcagcact agtttactca ggaaacttct taattcaagc
     1861 agaagtagat acatgggatg ttactagact acaagttggc atcaatccat ttggatttaa
     1921 ttggaaactc aatccaggag aaatatttac agcaccagaa gcgattctgg tttattcaag
     1981 taagggttta aatgccatga gtcaaacttt tcatcaacta tttagaaaac gcttagctcg
     2041 tggtaagtgg cgagaaaaag accgtcctgt cttaattaat aattgggaag caacatattt
     2101 tgattttgac gaagaaaagt tggtaaatat tgctaaaaaa gcatttgatg ttggtattga
     2161 attatttgta ttagatgatg gctggtttgg agaaagagaa aacgattgtg caggattagg
     2221 agattggcat gtaaatccta aaagactacc tagaggaatc ggcagccttt cagaaaaaat
     2281 tcgtagtttt ggtatgaaat ttggtttatg gtttgaacct gaaatggtga ataaggatag
     2341 tgagttatat cgcacacatc cgaattggat tatttctaca cctaatcgaa aacctaatca
     2401 tggtaggaac caatatgtat taaattttgg gttagatgag gttgttgaaa atattttcga
     2461 tcaaatgtgt aaaatcattg atgaatcaaa cttagattac attaagtggg atatgaatcg
     2521 tccattgact gatgtatttg acagtcactt gtcagcagat caacaaggag aagtattcca
     2581 cagatatgta ctaggcgtat atcgcttata tgaaaaactt ataacaaaat atcctaacat
     2641 actatttgag tcttgttcat caggtggtgg gcgctttgat cctggaatgc ttcactatgc
     2701 acctcaagct tgggctagtg atgattcaga tgcaattgaa aggttaaaaa ttcaatatgg
     2761 aactagtatg ctgtatcctc tttcgtctat tggtgctcat gtatcaattg ttccaaatca
     2821 tcaaacaaac cgtataacac ctataaaaac tagaggaaat gtagcttttt ttggtgcatt
     2881 tggatatgag cttgacttaa atgaattaag tgaaggcgat ttgaggattg taaaagaaca
     2941 aattgccttt tataaaaaat atagaaccat aattcataat ggtacttttt atagactatt
     3001 atcaccattc gatgatgata atcaaaccgc gtggatggtt gttagtcatg ataagaaaac
     3061 ggctattgtt gctcattata aaacattaaa tgaggtaaat gctccttacc gccgactgaa
     3121 attaaaaggg ttagataatg acggacttta taatgtagga caaaatagtt tgcgatctgg
     3181 aatggaattg atgagagcag gactagtctg ttcagatgca tctagtggac aaataaatga
     3241 tcagaatcga cgcccagaaa catttgattt tgattccaag atttgggtta taacacagga
     3301 ggaaaagtag agatgaataa ccaaaaaagc ttacttcaaa aaggagcaat cttaagtatt
     3361 tcactaatgt taacaagctc tcaagcaatt aatggtgtta ttccacaaat gaaacagtct
     3421 ttggggatat cacaaagtca aagtgaactt ttaggaactg caccaagtat aactgttatt
     3481 ttgtttatct tattatctag ttactttgcc aaaagaatag gaatgaaaaa gacaataatt
     3541 ttaggtttat tattagctgg tataggagga attattccag tatttacagc taccttccaa
     3601 accgttctta ttagtcgagt aatattaggt gccggtttag gagtatataa ttcattggct
     3661 gtgacatata tcagctcttt atactctggc aatactagag caacgctatt aggtattaga
     3721 aattcaatgg aagctttagg tcagacaatc cttatttttc ttgctggagt tttagtgaac
     3781 attaattgga cggcttcgtt tttagtctat gcaattgcgt ttcctgtagc tctcttattc
     3841 gcgctaaaag ttcctgaaat tagagatgaa aatagtgaca tacctgaaaa tcatgtaaaa
     3901 gaaaagatga atccaatggt ttttgcccta gttctatttg caatcttact cgtaatgaat
     3961 agtattgcta tttctgtacg atttgcatca attgcaactg aaattaaagg ggtaaacttt
     4021 aatgctagta actatttagc tctaatgcct atcttaggaa tactagcagg atttatgttt
     4081 ggaccaataa ataagtggat aggaaaagga accctatact tgggaattat attctttata
     4141 atttcaaatt tgttaattgc tgtgtcaaac ggtaatatga cgttcctgct aacgggttta
     4201 tttttatcaa gtataacagg atcatggtgc ttcccattta tctttagtaa cttagataaa
     4261 gtcactacaa agaatacaat taattttgct acttcattga tttttattgg ctgtaatatt
     4321 ggtaatttta tagctcctat tgctatgcaa ttagcacaat ttctaacaag aagtacaaat
     4381 ttgactgctc cattttttgt attcgcagga atatttattg tgatcctatt tgtaacattt
     4441 tttgcgacaa ataaaaaaaa tactaga
//
LOCUS       DAFLWQ010000142         4434 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.147, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000142 DAFLWQ010000000
VERSION     DAFLWQ010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.147"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..1035
                     /locus_tag="L1V16_002869"
     CDS             <1..1035
                     /locus_tag="L1V16_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HBN1277137.1"
                     /translation="DFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKDFFKLKMNN
                     LNVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTGNLSK
                     TIEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGD
                     TIRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGI
                     VYYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEM
                     HITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQL
                     GLVDNFNNIS"
     gene            1180..1485
                     /locus_tag="L1V16_002870"
     CDS             1180..1485
                     /locus_tag="L1V16_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277138.1"
                     /translation="MLNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDA
                     KISSYLFFLIHDEFMDYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            2102..>4434
                     /gene="esp"
                     /locus_tag="L1V16_002871"
     CDS             2102..>4434
                     /gene="esp"
                     /locus_tag="L1V16_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HBN1277139.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLVGVGLVLGTT
                     ELVQAQDEISPSTPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEEPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSASAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGKKVADLAIERRKDHENYGVGSITDNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSILDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAGEG"
BASE COUNT         1620 a          607 c          829 g         1378 t
ORIGIN      
        1 gatttccatt tctttactgg tgattttaat gagatgtttc ttctatacat gtttaaaacc
       61 agatattact tatttggtcc atttagagca aataatattg ataaagattt ttttaaacta
      121 aaaatgaaca atttgaatgt tgcaatggct gatagagaac gactctataa ttcattgcaa
      181 aatttgactt tgtattcttt aggagacatt cgagatattc tgattttagt tcattatttt
      241 tttactggaa aaatagaaga tctattccat gaaccgttaa ttgaatatac aggaaatcta
      301 agtaaaacta tcgagcaaat caaaatagat aatctgttat cacaaaatta cgatccagaa
      361 atatatctgt ttctttatga aaataaaata ctggaatatg ttaaaaatgg agatattcga
      421 aatttagaaa acatggtttt taatctgagt aatggaataa ttccaagtgt tagtggagat
      481 acgattcggt ctgaaaaaaa ttattctatc attgtttttg aaaagttagc acaaacgtct
      541 ataacattag gaatggatat aatagaagcg tatcaaagta gagatgcttt gatacaagaa
      601 aacgaattag ctgtatcgtt acctgaggtc ttaaaagtga gggattctgg gattgtttat
      661 tatactaagg aaatcggaaa aactaagata gagcatcttt ctcccttaat ttcttctgtc
      721 gttcaattca tcggcttaaa tatctataaa agaattactg taaaggaaat agctaattat
      781 ttttctgtaa gtgaaactaa attaagagaa agctttaaga atgaaatgca tattacgatt
      841 tataattata tctctaagcg aaaaatttct acggctaaaa taatgttgaa atcaaaccat
      901 actatcagtg aagtttcttt aggtttagga ttttcagatt cttcacactt ttcgagagta
      961 ttcaaaaagt acgcaggtgt atctcctaag caatatcaat taggtttagt ggataatttc
     1021 aacaacatta gctgagaggt tttattttat tatgagacta tatcatttac gtagtttgga
     1081 ggagttgagg aaattggatt ttaacaaaaa attttttggg aaatttctga tttgagttgt
     1141 ttcgtagaat ctgagcgtct aagtaatggt aataatagtg tgttaaatga atatgacaaa
     1201 gtagtaatta ataaagtaaa aagtttatgt gaagaagcta gagaatctat cagtcatatt
     1261 aatggtagca attttaagca aacattattt aatctgatta agctagatgc taaaatatca
     1321 agttatttat tctttttaat acatgatgaa tttatggatt atcaaaaatt ggatcagtta
     1381 attgaaagag aaagctggga agattattac gtgggtctaa ctttttcaga aaagttaaac
     1441 aactacaagt taatagatta taagtatttg agtgaaagca attaattatt catgtagagt
     1501 actagacact ttaaatatgg acaattcaat tataaagaaa aagaatcaat aatttaatga
     1561 ggctgtgaca aatgtcattt tttgtttcgc taaaaacgag tgaaaaaatg ttgataactc
     1621 caatcattcg tttaagattc taggaatcat tcaggaatgc tgtgaaaccg atactttata
     1681 attataaaga aggtgatttc aaattccgaa gaaggaattt gaagtcacct ttttacttat
     1741 gtcacagtct cattcagtaa tgcgggataa ggctccttat tccgctattt gaatactctg
     1801 aagtttaatc taagaaagag taatattttg aaaacatgct tcatcgcata gaaatgaact
     1861 taatttcaga aagaatacat acatatcttt ttatatgttt tcagctgctg aatggttaaa
     1921 aagcacaaat atccgaaaaa aacatgaaga aatgtacttt ttttgttgta atgtgcatga
     1981 aattctttaa gtaaactagt taacataagt ttagtaagat tcctattctg tgaataatac
     2041 gtatcagatt tatcttttat tcttactaag aaaataacta ttaagggagt tgatttgaat
     2101 aatggttagc aagaataata agagagtatt tctagaaaaa acaaagaaac gagtattgaa
     2161 gtacagtatc aaaaaattaa gtgttggggt tgcatctgtt ttggttggtg ttggtcttgt
     2221 cttgggaaca actgaactag ttcaagcaca agatgaaatt tctccaagca ccccacttga
     2281 aacagcgata agctccgtac aagtaggtga caaagtagct tcggggaata cttttcagga
     2341 gaatcctggt tatacgaaaa attataactt ttcggattta caatttagtc ctcaagaact
     2401 aactggagac acactaaaag gcaatacaat tggatttgaa gtttacggaa aacataatat
     2461 tgcagcatca actaaaaact gggaaatccg tcttcaatta gatgaacgat tagctaaata
     2521 tgtagaaaaa attcaggtcg atccaaagaa aggaattgga tcttctagac ggacctttgt
     2581 aagaattaat gattcgctgg gtagacctac aaatatttgg aaggtcaatt atattcgtgc
     2641 aagtgatgga ttatttgctg gggctgaaac aactgataca caaactgctc ctaatggggt
     2701 aattacgttt gaaaagagct tagatgaaat ttttaaagag ataggcatag acaatctcaa
     2761 gaccgatcgt ttaatgtatc gaatctactt ggtaagtcat caagacgatg ataaaattgt
     2821 accaggtatt gatagtacgg gctacttttt aacagattca gatgatttct ataatagctt
     2881 agatgtatct gaaaataatc ctgaccagtt taaacatgga tcagtaagtg caaaatatga
     2941 ggaacctaat actcaaacaa aagatggttc aggatccaca ggtgctaatg gagctataat
     3001 cttagatcat aagttaacga aaaattataa tttctcatat tcagcttccg caaagggcac
     3061 gccttggtat gctaattaca aaattgatga acgattagtt ccatatgtag cgggtataca
     3121 gatgcacatg gttcaggctg acaaagtaac atatgatgtt tcttttgaat cagggaaaaa
     3181 agtggctgat ttagcaattg aacggcgcaa agatcatgaa aattatggtg taggttcaat
     3241 tactgataat gatcttacca aacttattga ttttgctaat gcaagtccac gtccagtcgt
     3301 tattcgatat gttttacaat tgactaagcc attagatgaa atcttagaag atatgaaagc
     3361 aacagcacaa gttgaagaaa ataaaccatt tggtgaagat ttcatctttg attcttggtt
     3421 gtcggatacg aataaaaaat taatccagaa cacttatgga acaggttatt attatttgca
     3481 agatattgat ggtgatggaa accctgacga taaagaagag agcggagaca cgaatccata
     3541 tatcgggaaa cctgaattag aagaagtata tgatgttgac acaacagtta aggggaaagt
     3601 attcatccac gagttagcgg gaacaggtca caaagcccaa cttgttgata aagaaggtac
     3661 tgtattagca gaaaaaacta tcgctccaaa tgaaaaagat ggggctccaa tttcagatac
     3721 tgtagaattt gaatttacgg gtgtagattc aagtaaatta atcgcgaaag atgaattaaa
     3781 aatccaaatc gtttctccag gttttgataa accagaagaa ggttcaaccg ttattaagga
     3841 atcaccaaaa gcggttgata aacaaaccgt ggtagttgga tttaaaccag atgctaaaga
     3901 atcaattcgg aataataaaa acttacctga agatgcagag tattcatgga aaacagagcc
     3961 tgatacttct aacgttactg atagtacgaa aggtattgta actgttaaga tcggaaatcg
     4021 aactttcgac gtggatgtag agtttgctgt aaaagcttct caagctatgg aaaatgatgc
     4081 aacatacgta cctataacaa caactccaga aacgacagtt caaagtggaa aacctacatt
     4141 tgataaacca gatgttcctt tagctaaaga tgccttttca attttagatg tctataataa
     4201 ggacttcggt aatgcaagtg ttgatgcaaa tactggtatt gttacattca ctccagctaa
     4261 aggtgtagga gaatcggagc cgattactgg aacaattcct attaaaattg tttaccaaga
     4321 tggttctgta ggcacgaccg atttagcagt aactgtaagt aaagatattt atgaaaatcc
     4381 aggagaaaac attcctgcag gctaccacaa agtgaccttc accgcagggg aagg
//
LOCUS       DAFLWQ010000143         4417 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.148, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000143 DAFLWQ010000000
VERSION     DAFLWQ010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4417
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.148"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            682..1650
                     /locus_tag="L1V16_002872"
     CDS             682..1650
                     /locus_tag="L1V16_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1277140.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADVRNHDLDVRRYMGKVEY"
     gene            1661..2476
                     /locus_tag="L1V16_002873"
     CDS             1661..2476
                     /locus_tag="L1V16_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HBN1277141.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKEIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            2544..3254
                     /locus_tag="L1V16_002874"
     CDS             2544..3254
                     /locus_tag="L1V16_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1277142.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYIMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            3290..>4417
                     /locus_tag="L1V16_002875"
     CDS             3290..>4417
                     /locus_tag="L1V16_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBN1277143.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKN"
BASE COUNT         1485 a          660 c          921 g         1351 t
ORIGIN      
        1 aattcaccaa aaaggtgagt aatgccattt ttgaaaattg agcttgtttt atgtctacat
       61 ctgtatccgt atataatcca aaggattata aactcagaag agtctttatt ttttctgaat
      121 ataactactg tatcaaaaac aatcgattat gagacaaaac aaaatgacct cttttattta
      181 agaaaggagg tcattttttg tatcataaat tgtattaaaa tcaatgtatc actttttaat
      241 cagttttaag accataaatt gcgtactaaa agaaattctg caattcaaaa taaagcattt
      301 taagccattt tcaaatttaa gtgcacccat ctacccgtca aatcacttta ttttccactc
      361 cagtagtttc ctaattcaac tgtgtgcaaa aacgatttct tctaaacaaa tcaagacaaa
      421 cttataaacc ttcatcccag caccataatt atttaaatca taggcatttt tcgaaattag
      481 tatatgtact caagtttcac tgcagattat ttatattttt tagagaaata aatttttcct
      541 attgacaaac acaaagaaag cggatacaat gcaattatgt cacatgacgt tatatgacgt
      601 tatgtgatat ctttacattt aatcagttac ttttattttg gataaaatta acatttttaa
      661 aattttaagg aggaaatgtt gatggatgta gcaaaaacgg ttaacgcaat tgtagaaaaa
      721 aatgatggag agatttctgg aatttatttg gtggcttgtg gcggttcgct ggtagatatg
      781 tatgtctcag attattttct taaagccgaa gcatcgaagt gtattacagg cttatataca
      841 gcgaacgaat ttaaccatgt aaccccaaag caattagatg ataaatctgt tgtcattcta
      901 tgttctcatg gaggaaatac agcagaaacg gtaaaagcag gagaagtcgc tcaagctaga
      961 ggagctgtga ctgttggtct gactcataat aaaactgcgg atttattaaa ggtttctgat
     1021 catagtttcc tttacgaatg gggagatgat gcaaaaatag tcaataatcc tatggccatc
     1081 attcttgatt taactgtatc tttggtcaat gttaccgaaa catttgaaca ttacggtaaa
     1141 ttcagagaag gcatgaaggt tatcgatacc gtaattgaaa atggcattaa gcaggtgcag
     1201 gatcgtatta aagtgtttgc tgataagtac aaagatgaaa caatgtttta tatcttaggt
     1261 agtggaccat catatggaca tgcttatggt ttttcaattt gctctttgat ggaaatgcaa
     1321 tggcttgatt caacttctgt tcattctgga gaattcttcc atggaccttt tgaagtaaca
     1381 gacaaagata cgaattttat tctcttgatg agcattggac gcactcgtgc tttagatgaa
     1441 cgggcaaaac gattccttga taaatatgca gaaagagtag aaatcgttga tgcaaaggaa
     1501 ctaggattgg atatgatatc agatgaagtt tctgaattct tcaatcccat tttattctac
     1561 agtattcttt cagaatatcg ttcagcttta gcagatgtac gcaatcatga tttagatgtt
     1621 cgtcgctata tggggaaagt ggagtactag gaggattaaa atgaaggtat taggcttagg
     1681 tgataacgtc gtcgataaat atgaaaatct gggaattatg tatcctggag gaaattcatt
     1741 gaattttgca gtttttgcaa aaaaactggg acatgaaagt agctttatgg gagtttttgg
     1801 ctcagatgag gaggcagctc atgttttatc agcaataaaa gaaataggac tggacaacag
     1861 tcactctcgc tttgaaaaag gcgagaatgg ctgtgccaga gtgaagattg atgagggcga
     1921 ccggattttc cttggcagca attcgggagg tgttactcgt gaatacccga ttcagcttac
     1981 tgaagaagac agagaatatt taaaccagtt tgaattgatt catatgggat tatatagcca
     2041 tgtcaatcat ctattagaag agttacaaaa tgtttctgga aagatttctt atgatttttc
     2101 tgacgacttt acggaagaag aggttcagcg ggcaattgat aaagttgatt ttggcttctt
     2161 ttctatagaa gacttttccg atgaagaagt aaagcagttt ttgatgaagc atttttgtga
     2221 gcgaaatgat gtattgattg caacccgagg agaaaaaacg gctattggtt atgatggagc
     2281 aaagttttat gaagtgaacc ccgtgctaga agaaccagtt gatacaatgg cagcgggaga
     2341 ttctttctta acagctttcc tactttattt tctcgaaggg gacgatatag tcaccgcgat
     2401 gaaaaagggg aatgaatttg ctgggaagtc ttgtctggtt gacggttcgt tcggctttgg
     2461 tattcattac gattgagctt gttttaaatt cctgcatttg ataacctaaa gaaagaaatc
     2521 ccggtaaagt ggaggttaaa aaaatgctgg atacaaatgc acaattacca ttgtacttac
     2581 aattaaaaga aatattaaaa aataaaatca atacagggga gtatcccgag aatacgaaaa
     2641 ttcccgctga atcagagctg atagaaagtt atgaggtcag ccgaatcaca gtgagaaaag
     2701 cagtagaaga actggtagaa gaagggtacc tacttaaaaa acaagggaaa ggaacttttg
     2761 tcaaccggca taaagttttt cgtaaaattg aatatattat gggtttcagt gagagttgta
     2821 aatctaatgg ttttacaccg actagcattg ttttggaacg caagatcatt ccagcaactg
     2881 aagggatggc aaaaaaactc gatatcgctc aaggtgatga tgttttatat atccagagaa
     2941 agcgaatggc ggataacatc cccattatgt tagaaaacaa ttatttttct tatgaaagat
     3001 atagtttctt aatggaggaa gagctgactg attctttgta tgaagtactt aaagtccaag
     3061 gtaccttagc catcaatcct ggggaaactg cacttgaaat tgtcacagct gatgaccaaa
     3121 ttgccaaaat aatggaagta gctgttggga cgcccttttt ctttatggat actttaatca
     3181 acgatcaaaa caacatacca attcatgtag gtaatcaata ttacctggga gaagtatatc
     3241 gtttttactt atgatttcct gtttggattt caaggagtag attttattta tgaagcaaat
     3301 attgcggtca aaaatgattt ttgatggaga gcagccacct ttcaaaggtt atattgtaat
     3361 caatgaaggg atcattgaaa aggtggaaaa caactggaat tacagtgatc tattaaatga
     3421 aaacacggaa ttaattgctt atgatgatca attcgttatg ccagcaattc atgataatca
     3481 tgtatttttc agtggttatt tggctatgaa tgctggcata gatttaagcg atacatcttc
     3541 agctaacgag gctgtagagc gtattaaagc tgtaatgaac cataaaaaag cagatgaacc
     3601 aatttatgct catggctggg atgctgccct gtggaaaact gacccatcag aagagctatt
     3661 gaatgaaata aaccactttg gtccaatcac agcgatcgac aaaaatcgca gccattgttg
     3721 gatgaatgct attgctaagc agacttatgg ttttacagaa aaagaaacca gtgctgaaag
     3781 tcgagtatta ttaattaagg aaatgctagc aaacaaaaag cttttagcag aggtttacgc
     3841 tgaatttgaa gcattactgc tttcaaaagg tgttatatca atgaaagaaa tcgtttttga
     3901 tgacgcagaa tttctttcta atatacctca gaggaaaata cttagtaacc tatatgtgca
     3961 ggcagtccaa gaacctctac agcatgaact tctatatgag tataaggaaa aagttttccc
     4021 tgaaaaggtc cgctttggtg gagtgaagat catggtagat ggtgttgttg cggatagaag
     4081 tggagatatt tacggtgttt atcagtcagg agtagcttca cccgagattg actatgaggc
     4141 aattaaagca gaagttgctg cattcaatga agtagagatt ccttgctgtt tgacaacgga
     4201 aggagataaa gcgggttata aagctgcgtc aattcttgtc gaatttggaa agcggttacc
     4261 tgaaggcgtt tttaattcga ttagtgattt ggaaatggtt actcaaaaga cagcagaaaa
     4321 aatgaacgaa ggacaagtag tagcagaggt atatccacaa attctcggct tgaatcaaac
     4381 gttagaagag gcttacatgt caactgttat aaaaaat
//
LOCUS       DAFLWQ010000144         4414 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.149, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000144 DAFLWQ010000000
VERSION     DAFLWQ010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4414
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.149"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            274..975
                     /locus_tag="L1V16_002876"
     CDS             274..975
                     /locus_tag="L1V16_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBN1277144.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1584..2600)
                     /gene="tsaD"
                     /locus_tag="L1V16_002877"
     CDS             complement(1584..2600)
                     /gene="tsaD"
                     /locus_tag="L1V16_002877"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBN1277145.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2597..3061)
                     /gene="rimI"
                     /locus_tag="L1V16_002878"
     CDS             complement(2597..3061)
                     /gene="rimI"
                     /locus_tag="L1V16_002878"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBN1277146.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(3068..3610)
                     /gene="rimI"
                     /locus_tag="L1V16_002879"
     CDS             complement(3068..3610)
                     /gene="rimI"
                     /locus_tag="L1V16_002879"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBN1277147.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3594..4316)
                     /gene="tsaB"
                     /locus_tag="L1V16_002880"
     CDS             complement(3594..4316)
                     /gene="tsaB"
                     /locus_tag="L1V16_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBN1277148.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
BASE COUNT         1337 a          910 c          741 g         1426 t
ORIGIN      
        1 tatttattca ttgaaaaaat ttttttgaat aaattaaaaa aataaattat attatcgttg
       61 ttagcgttta ctatatgtat tattgttgtt ttttatacac aaatcattcg cttcaaaaca
      121 aattattcaa taccattgta tattttttac ataataacaa attatatttg taaagtatta
      181 aaacttgttt ctaatgttgg tatgttaaaa ctttacaaat tctttaaaaa aagtgacaat
      241 aaatatagtg aacaataagg agaggacttt ttaatgcgtg ttaataaaat cgattttcac
      301 ttttcaaaac tcagatatca acctgatttt gaacatttct cggatgaaga gttccaacag
      361 atcaaggaac atactgttct tcgttcttat aaaaaaggac agatcctttt cgacgatggt
      421 gatcccagac aacggttgta tatcttgacc aaaggactcg ttcgtttaga acgttatgat
      481 gaaagtgcaa cttattacta ctatgactat gtgaatacaa ataacctttt tcctatgtca
      541 ggaatgtttg gagaagagac ctacacttat acagctcaag cgatgactga tattgaaaca
      601 ttctaccttc ctgtttccta ctatgaaaaa ttagcacgaa aaaatcccga acagttgatc
      661 tatatgatac aaaaaatttc taaagtagtt gaaatacatg aattgcgtat ccaaatcgga
      721 ttgacctcta gcgcctttga ccgggtaaaa caaaatttat tcattttgaa agaagaattg
      781 ggcgtaccaa caaaagatgg tcatatcacc attccttatc cgatcacctt aaaagaatta
      841 gcagtgaata gcggcacgac acgtgaaact gctggacaag taatcaaaca actacgtgat
      901 tccgggctgt tagattatga caaaaagcgt tttactttct gtaagacagc tactactcca
      961 gctatgagag aataacgcga acaaaaataa gcagtgaccc tgataaatat cagggtcact
     1021 gcttattttc ctccctaaaa cttctgaaag atccggcagt tttagatcac tggacaagac
     1081 tcaaagattt tctatgtgtg tttcagttat gtaatattca ctgtttgcaa aaaatactgt
     1141 tagattaact agatgaagcg tcttgtcctc atccgatcta gattattcga tattcctcga
     1201 caataaacga ttactcagtg agggcaatca gaggaacgga taatgataaa taagctgtaa
     1261 aaaatagcaa aataacaata atgattaaaa gtatgtaaaa aatagggctt tgacaaaaac
     1321 gtgtcacagc cctatttcga ttaaacggtg tgtacctgtc aactcttcgg tcacaagtca
     1381 taatgttcat aaacatgagg agctgttttt tgaaattgtt ccttgtgaat cagagttaaa
     1441 cgacaggctt acgaactctt gattaaacgg cgttcaaaag cttgcatacg cggtaataag
     1501 aacagccagg tcaaaaacat gagaagccgt ttttcctggg ctgttcttat tacttgatgc
     1561 agggcagctt tttcacaacc tctttattca gataaaacca agcttggatc agcattcaac
     1621 tgatagctag caaaatttct tttttgcatt tccacatgtg ctgctgctcc aatcattgca
     1681 gcattatctc cacaaagtcg aagaggggga atcactagtt ctacctcagg gagtttagct
     1741 gccaaagcat cctgcaatcc ttcacgcaac ccttgattgg ccgctacacc tccagctata
     1801 atcagttgct tgactggata attttgacaa gctcgaagtg ttttagtaat caatacatcg
     1861 atcacacttg cttgaaagct agctgctaaa tcatttttgt ctagatcttc tccacgctgt
     1921 tgtgcattat gcaccaaatt gataaatgca ctttttaatc cgctaaaact gaaatcataa
     1981 ttatcttcat ggatcatcgc tcgcggaaaa tggtaattat cttttccctg atgagctagc
     2041 tgatcgattt cttttccgct tgggtaagaa agacctaata ctcttccaac tttgtcataa
     2101 gcttctcctg ctgcgtcatc tcttgtctcc ccaatgattt catatgatcc atcttcttgc
     2161 atatagacta attctgtatg tcctccgcta acaagaagtg ccatcaatgg aaactggaat
     2221 ggtttaacca gacgggctgc atagatatgc cctgccatat ggtttacagg aataagcggc
     2281 aattggtgtg cccaagcaaa agccttagct gcagaaatac caatcagcaa cgagccgaca
     2341 agtcctggtc cataagtgac agcgactgcc gataaatctt ctgccgacac accagcttct
     2401 accagtgcat cttccaagca taaggtgatt tgttctacgt gatggcggct agctacttca
     2461 ggtactacgc caccaaaacg tttatgactg tttatttgag aagcaacgat gttagataag
     2521 atctctgttc catttctaac gaccgctaca ctcgtttcat cacaacttga ttcaatcgcc
     2581 agaatcaatt cttcattcat ttcatcgtct ccgtttttaa ctttctgctc ataatgatcg
     2641 catcttccgt cggattgcga taatatgatt tccgtttacc taatatacga aacttttctg
     2701 attcataaag ttttcttgct gcttcattag atagacgtac ttctaaaaaa acatgcagcg
     2761 aatcttttat ttgttccgta atcagtaatt gtaacaaatg ccgtgcatgc ccttttcctt
     2821 gttctgaaac tgcaacagca atatttgtga tctcgacttc atctattact ttcgagtatc
     2881 caataaagcc acagatctgg ttatcttcag ctaaaagcag ataatcagag tgaggctgtt
     2941 ggatgtctgc caaaaactgc attttcgtcc aaggtgaacc atgtggataa gcattttcgc
     3001 taatcatcca tacgcattct gccaagtacg cttcatcaaa atcttttttt ctgcaaatca
     3061 actaatctca ctcattttct aaaagtttta tcatatccaa cgcatcttct tttgtttcag
     3121 tgtaatatct ttttttgatc gttgttgctt gaaaccccaa tttccgataa agtctttgtg
     3181 catcttgatt actcatacgc acttctaatg acatcgtctc acagcgattc attatagcaa
     3241 agttctcgat ttcgtcaata agcagcgaac cgattcgttt acgctgatat gccggtcgaa
     3301 cggcaatatt cgtgatatgg caatctaaac cgaacgctct tgaaccgata aaaccaatca
     3361 ttcttccatt atcaaagata cctagatata gatgaggaag cggtgacttc aattctgata
     3421 taaaggcact ttttgtccat ggcaattcgc cattatagac ttctcgttcg acatccagca
     3481 gctctttgat atcttctgta gtcaattctc ttagtacgta acgacgatcg atttgttcga
     3541 ctgttttttc tgtataaatc attttatctt gaaaaaagct tctggcatac gctctaaatt
     3601 ttttcaacat aactttcgtc tccaggtgtg tgcgtctcca accatttttc ttctgcttct
     3661 actcgtttta aatagcgagg aagaaaagct tgtttctctg caactggttc aactaaagca
     3721 cctaattgag ccacagttac accacttgga atatcccatg ctggaactgt attaatcatc
     3781 gcactaggca atatttcctt tatttcagag aagaatttgt gacaatcact cccgacgaaa
     3841 taaatagctt cattcagctt ttgtagttgt gtgaacaaat cagaagcaga aatatgtaca
     3901 tcttcaagta cagtttctaa tctattttct ttccagcggt atgccccagc gtatacattt
     3961 tttcttcgag catcaaacat gggcacaata atattatcca caccgatgca attagccgcg
     4021 atggttttca gactagatac tcctactagc tctttatcta atgtataagc aatcgttttt
     4081 gctgtcgtta cacctatacg aagccctgta taagaaccgg gaccatcaga aaccgcgatt
     4141 cggtcaatgt cttttggact tatttgaaga tctgcaaaca attggtcgat tgcaggcatc
     4201 agtgttacac tgtggttgcg tttgatattt gtttgtattt gtccaagaat ttgttcgtct
     4261 tctaccacac cgatcgccaa agtttggttt gcagtatcta ttcctaatgt aatcatatat
     4321 ttgatccttt ctgctatgac attctcgcct tccattgtag catacttttt tattctgagg
     4381 atgaaaatac caaaggcaaa actagtacaa taat
//
LOCUS       DAFLWQ010000145         4308 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.150, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000145 DAFLWQ010000000
VERSION     DAFLWQ010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.150"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            64..1365
                     /locus_tag="L1V16_002881"
     CDS             64..1365
                     /locus_tag="L1V16_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1277149.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            1392..1652
                     /locus_tag="L1V16_002882"
     CDS             1392..1652
                     /locus_tag="L1V16_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBN1277150.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(2651..3886)
                     /locus_tag="L1V16_002883"
     CDS             complement(2651..3886)
                     /locus_tag="L1V16_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBN1277151.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
BASE COUNT         1255 a          690 c          886 g         1477 t
ORIGIN      
        1 tgaacattct ttgcgttgtc atgcaatgaa tggttcatat tttattgaaa aggagtggtt
       61 ttagtggaaa agctgatgaa atgggtcgaa gagaaacttg tcccaccaat ggcaaaaatt
      121 ggtacacagc gtcatttatt agcaattcgt aatggggttg tttcaacatt gtcattgatt
      181 ttgattggga cattttttat ggtctttatc aatttaccgt ttcctggatg gaatgaattt
      241 attgcccctt attcggcaac gattgtttta ccctttagga tgacgatggg attgatggct
      301 atttatgcaa cttttgttat gggttcggat ctagctaaat catatggatt agatagtgtg
      361 acaggtggta tattatcttt aggaacgttc tttatgttac aagttcctgt aaacgtttta
      421 actcctgaag aggcacctct tggctgggtc ttacctatga gttctttggg agcatctggg
      481 atgtttgcgg ggatcttatc tatgattttt gcagtggaag tatatcgttt ctttaaaaat
      541 cgaaatatta ctatcaaaat gccagaacaa gtgccacctg ctgttgcccg tagttttgag
      601 gcattgattc caggtgcagt cattttaaca attacttggc tgattcgaag cgtcgcgggc
      661 tttgatgtaa acgctgcctt attatcgtta ttcgagcctt taaccaatat tttagggaat
      721 aatttgcttg gtgttttact accaatgttt ttgatccatt tgttgtggtc atttggtatc
      781 catggcatga gtattgtagg ggctgttgtt cgtccaatgt ggctgatcat gttggatgag
      841 aatgcaaagg cattggcaga tggtacagct gccacccaat taccctatat cgctcctgaa
      901 cagttttatc aatggacggt aacaattggt ggtgcaggag caacgatcgt ggtatctgtt
      961 ttgtttatat tcttctgtaa atcaaaattc ttgaaagagg ttggtcgttt ttctattatt
     1021 cctggtatct tcaatatcaa tgagcccata atttttggag ctcctatgat gttgaatcct
     1081 tacatgttca tcccgttcaa cttagttcct ttagttttga ctattatcag ttattttgca
     1141 gtcaaattag aaatggtcaa tagatttact gttttgccaa catggacatt accagctcca
     1201 atcggcggtt atctttcagc aggaaatgac tggcgtgttg ttatcttgat catgatcaac
     1261 acattgatag catttattat ctattatcca tttgtaaaag cttatgataa aaagatgctg
     1321 tcagatgaac aaagtcgtgg agaaaacgaa gtccagactg tctaagtttg gtttttagaa
     1381 ggtgggaaac aatgtattgg ctgattttat tttttgtttt tatcttttta ttaacggcta
     1441 gtcaccttat attgaatatg ctagctacat atcatattca aatcaatcga tggatttggg
     1501 cactggcatc atttttgatc gtgattcttc caaagatcat tgtaccgcat atgaatgttt
     1561 tgttttcatg ggggacatat gtactttgtg gaatttttgc tatcaatttt atgatcgagc
     1621 agcatagatg gtttgtcaca tcgaagcttt aaatgttcta aaagtggttg taacagaagt
     1681 ggttagcttc aagaaataag aagaaattta cgaaaattgc ttcttaaatt tttgtgaaat
     1741 gttggcttat ttttcgtttg gttgaactta ttaccgcaga tgcaagcttt tgaccaccgt
     1801 ttattcggaa tatgggactg tgacaaggct tttgtcacag ccctttttta cataaagatt
     1861 attattgttt taactgtttt ggcagaaaga aggaggaaaa aatggaaatt ttatcagcaa
     1921 tggatttaga attagtagat ctactaccaa agtgatcaag tcaaatatag atttgggagc
     1981 ttacaaccat atagtagggg ctgcagtatg gtgtatgaat ggtaatatgt atgatgtgag
     2041 tgtttattca aatcatgaaa cgtgtataga aataattgtg ctgggaatag caatcagtca
     2101 tggtgaacgt gacttttagt gtatcgttgc tgacgacata gaacattctg acatgatcta
     2161 ctcaatatgt ggggattgct ggcagtttat ataggagtat gcatcggatt gcgagatcat
     2221 tgtctcaaca gaagagggag gttgattatc aaagataaag tggtaaatcc tacatttgat
     2281 ttagtaattg ttgaggggac tagcggcaca aatctctaca aagcgatgct tctagatcta
     2341 tatgacacat tttaagaaaa tgtatttgcc taattattat ggtctttctt ttgaagaaac
     2401 gttgagatga tccaaccaga gaaaggtgtc aaagaatttg actaagaata aatggcagac
     2461 gctacctatg ctcatttgga tagcgtcaga tcttttattt taaggatgat tttgtgtttt
     2521 ttagacaccg taatttaagt aactctaact tttcaatcca ctatttactt tttttgtatt
     2581 ttcactgtct gggtctcgaa tagcgaaatt actgatgagt ctctattaaa aaagcttttt
     2641 ctacttgaaa ctatattggg tggttgctca ggaaggtttc gatttcttga attgcttgtt
     2701 gtggaccatt tattggaaaa acggcttgca gcgtgcgtgc ctgctgacga atcttgggtg
     2761 aagaaacttc gcgcagagca atctgcagtt ttctttcagt cactggtttt gtgagggcga
     2821 ttgcgtttcc gtattttaca caatagtcaa tattacagct ttgctcaaat tgcatcccca
     2881 caccgataaa cggtttgccg gattcacagg cagtttggac ggtcccttcc ccgccgtgga
     2941 taaaagaaaa atcaatgaat tcatgcaaaa gatgactaga cagatattct gttattaaaa
     3001 gatcttctga gtcagattga atgtcatcaa gcagatagtc aataggtgca ataaccgcta
     3061 gatccggttg tttttgtaag aagaacaaaa ttttgcgtaa catacgcgga ttgcctgaac
     3121 tacccattgc gaaatagata atacgttttc tttcttgttg ctttcgctgt ataaaagtta
     3181 gcacttcttc aggcaaggaa gtactgagct tagcaaaaat tggaccaacg attcgataat
     3241 tttccggcag ctgttcttct tccaaaaata gtttaggcgt tgtgatgaga tttagatcag
     3301 catccatcat ttgtaaactt gtttttggta aaggaagcat ttctttttgt gcagcgtgtt
     3361 tgaaggcatt ggggatccat cgggtattta ctatacgctt ttttgtccag tgccaaaggg
     3421 gattgcttaa agggccgaag aaacgtaact cgtggggcat cagcgcatgc tctgattgaa
     3481 aaaaaggttc actcaaagca tagggtttaa catatactaa aggaatcttt ttattgcggg
     3541 ccgataaaaa aattgtcaca ttcgaacctg tcacaatcag tcgaggctca aacttagcaa
     3601 tcagactctg ttcactagtg atacgagagg caaccatttc tttggtaaaa gggtttttaa
     3661 gtgtacgcaa ctggtcaaat tttatgattt gttcttcttg ttttttcgta aggatcggcg
     3721 ctagtaaatg atactcaaag ccactttctg tgatcaaagg agcaaaagtt ttagaaaagc
     3781 caaagaatac acagtaataa cggtctttca tagctttggc aacctcaatc attcgtgttg
     3841 tctcagctaa attgaatact gcaggagcaa aaagaattgt cttcatgaaa tcctccttat
     3901 tggaatgagt ctatcccttc gtttcttact agtatactaa aaaacacagc gttcgagtag
     3961 cctatgtata ttttgaatat taaactgtct ctcgctgttt tcacaacttc taaatttaaa
     4021 ttttgtaatc aagttgaaac tccaattttc aaaaaaacac gcaacaattt tttgatcgat
     4081 ttatatgttg tgccagataa atacgagaag ttgtgtcatt aaaaataaac atgagaacat
     4141 aaaaaaataa aataattata ttaattgata ggtgtgctgt cgtcattata cacacgtaag
     4201 aaagaaatag ttatgtttaa aaatattctt agactttctc gccatgacaa ttttcactat
     4261 gtgttataac tgtaaacgat aattattcag ataacacaaa aagaaatc
//
LOCUS       DAFLWQ010000146         4282 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.151, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000146 DAFLWQ010000000
VERSION     DAFLWQ010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.151"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(37..1257)
                     /locus_tag="L1V16_002884"
     CDS             complement(37..1257)
                     /locus_tag="L1V16_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBN1277152.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1277..1888)
                     /locus_tag="L1V16_002885"
     CDS             complement(1277..1888)
                     /locus_tag="L1V16_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBN1277153.1"
                     /translation="MKMKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELP
                     LFNKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVD
                     KPVMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLID
                     EEQVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1931..2863)
                     /locus_tag="L1V16_002886"
     CDS             complement(1931..2863)
                     /locus_tag="L1V16_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBN1277154.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
     gene            complement(3284..4144)
                     /locus_tag="L1V16_002887"
     CDS             complement(3284..4144)
                     /locus_tag="L1V16_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1277155.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
BASE COUNT         1219 a          861 c          701 g         1501 t
ORIGIN      
        1 tttattcttt atttaaaact ttgcaacaga acctttttat tttacagaag cactcgaaac
       61 tgcatctact gcagtttcat cgtgtgtgct ggcgctggtt actgcatctg tttttccacc
      121 atgaacagat gcacttgaaa ccgcatcttc atttccaaca agttgttgac ccgtttgttg
      181 taaataccac tcaatgattg gtttgaaatc aagaatgtat tcattgattc cagcatactc
      241 tccattttca tcatgcattg cttggtaatt atgcacaata tatttttctg gcacttgttt
      301 tggtacatga acacgtaccg catctgttgc tccgcttcgc agttgttgaa ttacccactc
      361 tacattttta tacgattttt ctgggtgaca gttggctaat ggattcccta cctgaccggg
      421 cacacgagca gctaacatct ctttcgcttc ttggcgcaaa ttataatata aaaattggtt
      481 attattatct gcaaaagtta attccatcgg catcgaatct aaaaagtaat tgatttgatc
      541 cactgtcaat aacccacgat ttaatttgac gtaagtattt ccagaaacgg caccgactgc
      601 ttcagaagct ttttccaacc aatgatcatc tgacatatca acatcgggta ttgtcgtagc
      661 aattgttcct gtcgcatgca aatcttctgg tggaagcttt ttaggccctg ctaaggtaga
      721 cacgacttta atgaatttta caaaacttgc taatgtactg cctaaaaagt caacagttcg
      781 tggatcaatc aagcgatctt cttggtcaaa tgcttctttt gcttttccca ataaaaattc
      841 atttccgggc atcactaatg cattcacgcc tggtgcgtcc aaaatttggc gcaagtgtaa
      901 ttgcgcgcgt gaagttcctt gatcgtagta agaagcaccc acaaccatta caggtttatt
      961 ttcaagtgga tggattttaa atgatagcca ttcaagtgca cttttcaatc ctgctggaac
     1021 cgtatgattg tgttctggcg tagcaataat taccccatca gccattaaga ttttgcgatt
     1081 tagctgttga atagcaggac tatttgtttg atcatcatct tgattgaaca gaggtaaatc
     1141 tttgatttca atgatttcta aattaaatag ttcatgatat tgtttttgga taaatgttaa
     1201 taatttacgg ttatatgaaa gttcagctgc tgatccgacg atacctatta atttcatctt
     1261 tgtttgctcc cctcgattaa atcgtttccc atgaaaagct ttcggcttca cgtttatttg
     1321 cttggtgcgc atgttgcaat tgactagtga ttgtgacaaa gagtaagaaa tctttgaata
     1381 gttcacgtaa ttttgcgact tgttcttcat caatgagtcg tccttgctca tcaaaggctt
     1441 ggagtgaatg acccaataaa aattctgagc ttggcataat tcgtgccttt aactctggtg
     1501 aatccaatat ttggcgcaaa tgtgcttgtg cgcgtgaaga acctaacgtg ccataagacg
     1561 ctccggtaat catcactggt ttatccacaa acggaaaaat accatatgaa agccaattta
     1621 atgcgttaat caatgaagca ggaaccgcat ggtcatactc tggtgtgctg atgattacgc
     1681 catctgcttg ttcaattttt ccagcaattt ctttaacaac atttggtagt tctgtgtttt
     1741 caggtttgtt aaatagtggc agctccttga tttcgacaat ttcgatttct gcctcattta
     1801 caaaataatt tttcataaac tgtaataatt cacggtttgt tgaccgcgtt gaatttgttc
     1861 ctactaatcc aataaatttc atcttcattc tctttccttt ctaacatcga tttctgactg
     1921 ttcgcacgta ctaaattttt tcaaatcctt ttgtatacaa gaattgattc tcttttgtta
     1981 caactgctcc ctcgataccc ggctgttctt caagcgcttt caacacttct aaagaagatg
     2041 ctccaaataa acgtgtagtc cagatttctc catctacaga agaatcagac aaaatcgtca
     2101 ggcttgctac gtcattttta actggaaagc cagttttcgg atcaatgatg tgatgataca
     2161 ctgacgaacc attttgtaga taacgttcgt agattccaga ggtaactaaa gattggttgt
     2221 ttagtttaac caccgcaagc gactcttcac gtgaaccttt aggatttcgc aaaccaatac
     2281 gccaagcacc atccgaacgt cttggtgatt caccaaaaac aacgatattt cctcctaagt
     2341 taactaaagc aaacgctgca tttcgctctc ggcaatgtgt aattaattta tctgcaatgt
     2401 aaccttttgc taacgccccc aagtcaatca tcattcctgg tttggttaaa aaaacggttt
     2461 tcattttttc atctaattga atttggtgtg gatccgttag cagaagtaac tcagttatct
     2521 ctgcttttgt tggaaccaat gcatcttcaa atccaatgtg ccatttttgt acaaccggac
     2581 caatagcaat attcagataa ctatttcttg cacaactatg tgcttttcct aatttgatga
     2641 gctcaaaaag ttcaggatgt acaatcacag cttgtcgtcc agcagcttga ttgatggcca
     2701 ttaattcaga agttgcatca tgtgcgctga agcgatgttc ataaacgtgc aaccattcgc
     2761 ctaactctgc tagtaatcga ctaggctctt catgcccaac ttgtaatgta attgttgtcc
     2821 ccatcatttg ccagattttc gtttcttcga tcacctgatt cattttgtac cttctttact
     2881 tgaactacgg attacatgag taattagttt ttatttttgt tactgttttc acaaccagat
     2941 gatacgcctg ctagatttat ttgtcaaccg attttatata tttttttata taataaggta
     3001 attttaatat aaaattttat attgtaaaaa aacaaataag ggaaacaaac aacacatttt
     3061 tgtgtgttgc ttatttccct ctaactatcg ttttctattt gatggttaac ctacttaaaa
     3121 taaatactgc aacgacaaac ggagatcaag catgctttgt aacgtatttt acgataatta
     3181 cgactttatt ttattactct atcttgctgc catacccgtc tatccctaat catctttggt
     3241 gaattttttc aaagttagca taacaaaaat aagtattttt tccttagtta atcaatagta
     3301 tcattttttt catatgattt aattcatcaa ttaatttttt gtttttatta attttagcaa
     3361 aagctagtgc atcttgaatc aattcgagca cttctgcctt cgacttattt ttagcctgtg
     3421 cgttcttcgc taattgggca gcagctcgtg ctaagtaata agtcaaatgg ttatccgaac
     3481 aaatatcgat tgcgtaattt agtagtgcat cacttgtttc caaatcaccg tcttgcgcaa
     3541 aaaaaacacc acaatgaaag acgatattta acacccgcca gatatcttct gttgtacgaa
     3601 tcggatacgt ataaattttt tcaaacactc gattgaaata aacttctgct ttttccaact
     3661 ctttttctct agcatagacc attccaatac ctgtatatgc caataaacga aacaacgtgt
     3721 tggctgtttc tgccatcaac aactgatcaa aatggaacaa cacatccgta attggtgcat
     3781 tcgtaaaaat catttcaaat ccttttagat agtagtaacg tgcaatcagc tcagactcgt
     3841 caattacctt gggatcaatg gctgctaaaa tctgtgtcaa ttgttcatat tcactcgtaa
     3901 tcagtgaaaa ctctgctttt tctagctgtt catcaagttg tgtattgatc acgttcatcg
     3961 aagaaaaaag ttcaactaac ggaagattga ttcgattaca taatttgatt aaaattttta
     4021 acgaagggac ttgaccattg ttctcaaatt tacttaatgt tgcttgtgta caaattcctt
     4081 cagacacttc tttttgagat aagttggcag cctttcttgc cgtaataaat ttttcaatgt
     4141 tcattatttt ctctccaatc agacctcaca cgaaaatcat ttctgtctcg attttagcat
     4201 gttttctttg ggaatgcttt aggttctgtt gcaaagtttt aaataaagaa taaagtccct
     4261 tacggtatct atgatttaag ct
//
LOCUS       DAFLWQ010000147         4250 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.152, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000147 DAFLWQ010000000
VERSION     DAFLWQ010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4250
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.152"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            50..487
                     /locus_tag="L1V16_002888"
     CDS             50..487
                     /locus_tag="L1V16_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277156.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWVFYLVKK"
     gene            582..1466
                     /locus_tag="L1V16_002889"
     CDS             582..1466
                     /locus_tag="L1V16_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBN1277157.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPEAINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSILLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            1688..>4250
                     /locus_tag="L1V16_002890"
     CDS             1688..>4250
                     /locus_tag="L1V16_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277158.1"
                     /translation="MNQYVKKLIASILFVFPLLMVTSVFADVEKTSESTQSENQSFDK
                     TTFSEESITSETTESQSEAPTSNTRQEENKTSETSEVAEQTSDSSEEVQVRVVSADGY
                     SEAATTEELTQLLADESVAKIRLTQPLTLDRELEIKRDIVIDFGGLAHNFGTHHIYIN
                     ETPQSIEFQNFKGTAAHPGGLIPNIDGNAIIIAYMSDFWGNRYHFTGEIKFTGTLDLY
                     DGSKLGLIYAPRATVTLDGVSGVLDVQPVKEGMNAAPGKAYFCRSYQLNVINGSQLYG
                     PYLGKFYGFLDSGDETGSGKTAPGLHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVT
                     FKVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSRVAVSNDGKITINTATTGGFRLQG
                     DSSQIHVSSGGQISVKMAGDGDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSA
                     VRFENGTQKLTVTNGGSLKVRNAGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFT
                     VTGEKSNIDIRADSGATVDTTGDIDLNFMAGEKTYLVMVGKTGEDKTGIISGDVLNVD
                     LESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKAGVTFDNFEKDP
                     DYFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRV
                     PTNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSPVEITALTQGQTDE
                     NEGTGYNPWGEGEQGGLFEVQVPNEERLTTGDQVQIVAAKKVRGGQEVTELDSAKTTV
                     DVIPPEPAKLSTTLINAASRSITGTGEAGALVSLKKNQAVLSETTIDDTGKFVLSI"
BASE COUNT         1392 a          713 c          959 g         1186 t
ORIGIN      
        1 atcttaaata aagaaaacga tattaaaaaa tgcacgtaga agtagataaa tggagtggtt
       61 ttgcaaattt cttttatttc tagaagttat tcacgtatac ggatttgttt ttctcacaaa
      121 taaaaaggca ggaagtacaa tggatcattt gtatataaaa tatattcatc aattttccgt
      181 tttggtatta ggcacactaa ttatagcggg gattgttgca tttattattc aaggtcgtga
      241 catattaaca gtacatcaag agtttttcag ttatgcattt ggtattcctc tgatcgctat
      301 aaggtctgat aacaaaaagt ggaagaaacg ctattacatt ctcttgctat ttttgtgttt
      361 ttatctgcca cctaagattt ttactttatt aggtatacaa tgcctatcat tttcttttat
      421 ttcctatatc attgttttaa ttttcctcag tttcatagta tgggtatttt atcttgtcaa
      481 aaaataaatg aatgtttcat gaacagtact tcatcacagc ctaatttttt tctttatgct
      541 atcgttatat taaagaaatc aatcagaagg gaaagaaagt gatgaaaaaa gttttattag
      601 tggtaaaccc cagttcaggc ggtgaacaag caaaggaatt tgagcaatta gcgatagcaa
      661 aattggaatc ggtgtttgat gaagtggtcg tcttgcatac aaaaaaagca ggggatgcaa
      721 aaaactttac tcgcgaagcg gctacggaag ggtatcatag tgtgtttgtc atgggcggag
      781 atggaacagt caacgaagga atcagtggaa tcgctgaaca agaacatcgg ccaaatttcg
      841 gatttttccc attgggtacg gtgaatgact tggctcgagc attagggata ccgctagaac
      901 ctgaggaagc gatcaatcat ttttcgattg aatcagtcaa gccattggat attggaaaaa
      961 taaatgacga ctattttatg aatgtcgtcg caattggctc tatccctgaa gcaatcaatg
     1021 atgtagatgc ggagaagaag acgaaatttg gaaaactagc ttatttcatg tcaggaatca
     1081 aacagttagc ttccacacaa tcctactcgt ttcacgtaga agttgatgga aagaaggaag
     1141 aaattgagag cagtatcttg ctgataggac taactaactc agtaggcggt tttgaaacat
     1201 tacttccaaa tgcaaaagtg gatgatggta agctccattt ggtttattta aaagattctt
     1261 ctttgatcga tacgcttaaa acattgccag acctattaaa aggagtagat gaatctacga
     1321 aaaatctagc ctatcttact tgtgagcaat tagttgtgtc attagctgat gaggaagaat
     1381 tgacgacgaa tgttgatgga gatgaagggg ataaattacc tgtgacaatc aaagtgttac
     1441 cctcacattt acaggtttat tgttaaaatg gaggttgtga ccgaagagtt gtcaggagga
     1501 catcggttgt tcggaataag ggactgtgac aagacttttg tcacagcctt tttttgtaca
     1561 aaaaagaaat tttcacctaa cagaaaaatt tgccataaaa atacatattt taaatatgaa
     1621 agtacaatta caaataaatt aaaacgttaa aataaaattg tcaaaacgtc agagaggatg
     1681 gtggagaatg aatcaatatg taaaaaagct gattgcgtcg attttgtttg tcttccctct
     1741 cttgatggtg acatccgttt ttgccgatgt agagaaaaca agcgaatcaa cgcaatcaga
     1801 gaatcaaagt tttgacaaga ctactttttc agaagaatca attacttctg aaactacaga
     1861 atcccaaagt gaggcgccta cttctaatac aaggcaagaa gaaaataaga caagtgagac
     1921 ctcagaagta gctgaacaaa cgtctgatag cagtgaagag gtacaggtta gagttgtttc
     1981 agcggatggg tacagcgaag ctgccacaac agaagaactg acgcagcttc tcgcagacga
     2041 atcagtagct aagattcgtt taactcagcc tttgacttta gacagggaat tggagatcaa
     2101 gcgagatatc gttatcgatt ttggcggact tgctcataat ttcggcacac atcacatcta
     2161 tatcaatgag acacctcagt cgatcgagtt tcagaatttt aaaggaacgg cagctcatcc
     2221 aggtgggttg ataccaaata tcgatggaaa tgccattatc attgcttata tgtccgattt
     2281 ttggggaaac agatatcatt ttacgggaga aataaaattt accgggacac ttgacttata
     2341 tgatggttct aaattaggcc tgatttacgc ccctcgtgca actgtcacat tagatggtgt
     2401 ttccggtgta ttggatgtcc aaccagtgaa agaagggatg aatgccgctc cgggtaaagc
     2461 ttatttttgt agaagctatc agctaaatgt aatcaatggt agtcagcttt atggaccata
     2521 tctaggaaaa ttctatggtt ttctagattc aggtgatgag acgggcagtg gaaaaacagc
     2581 accaggactc catatcttga gtggttcaaa ggtctctctt gactatgatc gggcagatgg
     2641 cgtcagcgat gaaggagagg ctgtcgatac gctacccggg aatgtcacat ttaaagtcag
     2701 tggctcagga agtgaatttt cggtaaatac aaagatcaat attaccaacg acaacaatcg
     2761 cggaattatc caaatgagag gctcaggatc aagagtcgct gtgtcgaatg atgggaaaat
     2821 cacaatcaat acagcgacta ctggcggatt tcgcctgcaa ggagattcta gtcaaatcca
     2881 tgtatcaagt ggtggacaaa tctcggtcaa aatggctgga gatggcgacc aacctggaaa
     2941 caatgggatg cgttttgtag ggaaaggact ttctttgatc gtagaaggag ccggatcagt
     3001 catcgatatt gataagcaaa gtggtcgttc tagcgcagtt cgttttgaga acggtacgca
     3061 aaaactaaca gtaactaatg gaggctcatt gaaggtaaga aatgcagggg atggcaaatc
     3121 ttatgtgaac agactcaatc aaggaaacca agcgatccaa ttttatgacg cttctggttt
     3181 tctagaaagt ccagggtcag ctgattttac ggttactgga gaaaaatcaa atatcgatat
     3241 acgcgcagat tccggagcta ccgtagatac aactggagat attgatttga actttatggc
     3301 tggcgaaaaa acttatttag tcatggtcgg gaaaactggg gaagataaga ctggcatcat
     3361 cagtggggat gtgttgaatg tagacttaga atctcctacc tatttcgatt tccaaaacaa
     3421 acggatcgga agcgagacta atggcatagg tggctgggta tttcaaggaa atggcgattc
     3481 ttctttgaag atcgctcatt cagaaattgc tttatggcga aaggcaggag taacgttcga
     3541 taactttgaa aaagatccgg attatttttc tgatatgaca gacttatcga tcaatggaac
     3601 cgacttaggt aattttgtat caagccctag tgcaggttta acaaatgaat ttgctcagac
     3661 aggtgccgga atgaaaaatt ataatcgaat cagtgccaat aaccagcttc cgatgattga
     3721 atccttaaga gtaccaacga atgcagataa aaaaatctat gggcatgtcg ttgttcccga
     3781 aggtgtcgag gcaaagccaa gagatgcttg gacaggcgaa gtagaagtga ctttacgtat
     3841 tacttatgca gatacgacga aatcacctgt agaaattact gctctcacac aaggacaaac
     3901 agatgaaaat gaagggacag gatataatcc gtggggagaa ggcgaacaag gcggtttgtt
     3961 tgaggttcaa gtacccaacg aagaaagact aacaacgggg gatcaagtgc aaatagttgc
     4021 tgctaaaaaa gtaagaggcg gccaagaagt gacagaactg gactctgcca aaacgacagt
     4081 cgatgtgatt cctcctgagc ctgctaaatt aagtaccaca ttgatcaatg cagcttctcg
     4141 ctcaatcaca ggtacaggcg aagcaggagc tttggtttca ttgaaaaaaa atcaagctgt
     4201 tttgtccgaa acaactattg atgatacagg taaatttgtt ctttctatcc
//
LOCUS       DAFLWQ010000148         4155 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.153, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000148 DAFLWQ010000000
VERSION     DAFLWQ010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4155
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.153"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            29..685
                     /locus_tag="L1V16_002891"
     CDS             29..685
                     /locus_tag="L1V16_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBN1277159.1"
                     /translation="MIVILGFAFKLDSILIVMVALVVTALTGGLGIQGMLELLGTSFV
                     NNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGIFRMIFAAFNV
                     SFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCWFFGQVLFIGG
                     AGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKLAKKYYPGKGQ
                     "
     gene            687..1631
                     /locus_tag="L1V16_002892"
     CDS             687..1631
                     /locus_tag="L1V16_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBN1277160.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            1830..2474
                     /gene="pcp"
                     /locus_tag="L1V16_002893"
     CDS             1830..2474
                     /gene="pcp"
                     /locus_tag="L1V16_002893"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBN1277161.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            2553..3830
                     /locus_tag="L1V16_002894"
     CDS             2553..3830
                     /locus_tag="L1V16_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277162.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
BASE COUNT         1331 a          728 c          918 g         1178 t
ORIGIN      
        1 ggaaaattat cttagccttt taggcgtctt gattgttatt ctcgggtttg catttaaatt
       61 agactcgata ttgatcgtaa tggttgcttt agttgttaca gctttgactg gcggtcttgg
      121 cattcaagga atgttagaac ttttaggtac aagttttgta aacaatcgcg ggatggcgat
      181 ttttatcatc attatgttgg caacaggaac gcttgaaaga aatggtctga aagaatcagc
      241 ggcttccttg atcaagcgat tcaagaaagt atctgctggt atgattgtag atatttatgg
      301 gatctttcga atgatctttg cggcttttaa cgtgagtttt ggtggagttg ctggatttgt
      361 tcgtccaatc attttaccga tggcattggg gaccatcgaa tcaaaagggt tagaagtcca
      421 tcctaagcat gaagaagaac taaaaggtat ggcttcagct atggaaaatg tctgctggtt
      481 ctttggccaa gtactattca tcggaggagc aggggcgttg ctagtccaat caacactgaa
      541 agatctagga tatgacgtaa cattgggaca gcttgcttta gtggaagttc cagtggctat
      601 cacggcttta gttgtggcaa gtgtctactt ctatcttaaa gaaaagaaat tagcgaagaa
      661 atattatcca ggaaaggggc aataagatgg acttttttac aaatcctgat attttattag
      721 gcgataaatt actggagatc ctttatatcg tgatgggact cgtattgatt tacactggag
      781 taagaaattt aacagataaa accaatcctc atcgttatgg gtcagccttt ttctggacgg
      841 tcttaggggt agttattgca ggaggaagat ggcttccggc aatcgtgaac ggtggcttga
      901 tctttgcgat gaccatacca gcaattgcta agaaagtcag caaaggagaa agccggcttc
      961 catcaaaaga atatatggaa aaaatgtcag acaaactagg aatgaaaatt tttattccag
     1021 ctttgagtat cggtgtcttt gcgatcttgt ttgctctatt taccaattta ggtgctttag
     1081 tcggcgtggg cgtcggtgtt tttgcagcca tgctaatctt gatgttcttt tctcgagata
     1141 atcgaccaag tacattttta gatgatgcag cagatatgct gggcacagta gggccgttaa
     1201 gcatgttgcc aatgctttta gcttctctag gtgcggtatt tacaagcgct ggagttggga
     1261 cagtgatttc caatgcagta ggtacgatcg ttccagaagg aaatgtgaac atcggcatca
     1321 tcatttacgc tcttggcatg gtgatattta cggtaatcat ggggaatgca tttgcggcca
     1381 tcaccgtgat gacggttggg atcggtgcac cattcgtatt tagtcatgga gcgaatccag
     1441 cgttaatagg aatggttgca ttgacttgcg gtttttgtgg gaccctgctg acaccgatgg
     1501 ctgctaactt caatatcgtg cctgtagcga tgctggagat gaaagacaaa tacggagtga
     1561 tcaaaaacca gttgtttatt gcgttattta tgctagtttt ccaaattgct tatatgattc
     1621 tatttaaata atagaagaga ggggttgtga cagaataatt gtcgcaacct cttctaacat
     1681 tgtagtggaa cactattttt ttataagaat atattaagtt tgatctgtta tgttatttaa
     1741 actattgttt cctttattta cgctgttcaa ggaaaatggt atgataaaag ataaccatat
     1801 gttaaatcaa tcggacggag gaacaacaga tgaaagtact agtaacaggt tttgatccat
     1861 ttggtgggga caaagtgaat ccagcctatg aagcagtaaa aaaaatgcca gatgaaatca
     1921 gcggtgctga aatcatcaaa gtggaagtac cgaccgtatt cgaaaaaagc agtcaagtag
     1981 tcaaagaagc catccaacag caccaaccag atgtcgtgat ctgtgtcgga caagcaggtg
     2041 ggcggtcagc agtctcgttc gaacgtgtcg caatcaatct agcagaagca agaatccctg
     2101 ataatgaagg aaatcagcca ttcgatacgg ctttagaaga aaacggtcca gccgcttact
     2161 ttacctcatt gccaatcaaa gcaatgacaa aaaatgtaca agatcatggt ctaccagcgt
     2221 acatctctta tacagcagga acatttgtct gcaatgatat catgtatcgt ttgcttcatt
     2281 tgatcgaaac acaattcccg gcaattcgag gtgggttcat ccacgtgcca ttctcacccg
     2341 atcaagtgat cgatcgtcca gtgggtacgc cttctatgtc tttagaagac attgcttctt
     2401 ctttgactta tgcagttgaa gcagcagtag aaaataaaga agatatttcc ggaaatgccg
     2461 gaacaactca ctaatttagc aagaaacact ggctggttgc taacgttatg ttagtagcca
     2521 gctttttgta attagaaagg aaagaaacag ccgtggaaga atggcaatcc gtctttgaag
     2581 aatggtttcc aaaagaaatc agcaaaagct atcccatcaa aatttctaaa caatacacaa
     2641 gcagtcaacg ttgggagatc tatgcaaaat taacgaaaaa acagcgggaa ctagtcgata
     2701 agcaccgccg atatctaatc agctctcgtt ttatggaaga acattattta gctgcaacag
     2761 attgggtgtt ttctgacttc aagatcaatc cgttttttcg aacaaaacga agccagcaaa
     2821 aattgtattg tgagtgtggt agagaattaa aagtgcaata catcgttaaa tcgccaaaaa
     2881 ccggaaagat cctaaaacta ggcatcaacc actttgccga tcacctgcat gtctctccga
     2941 cagtggcagc ttcgatccat cagggaatga caaaagttga tctggcctta gacgaattat
     3001 tatggcttaa gcagaagaat atcgattttc ctgaaggact atggcaaaaa tactgttttg
     3061 tcttgtacca aaatcgtcgg atgaaacagc catatttacc ggatataaaa ttagctcagc
     3121 ggctcgcaga atttcgccaa gtagaaatgc cgatttacat agcggattat caagcattgg
     3181 aaaatgaaat caagaaaata agtgaacaca tcaatgggca gtcaaaaaag cgacagataa
     3241 aaaaagaact atttgacgac tttgcagaag aattagtaaa ggatgtagaa gaattcttga
     3301 tcaactatcg cgcattttta cgtaaagatt ggcaatccat cgtatatgaa gaagtgccag
     3361 tacatcctaa tgcttatttt gaaacattta tttccgtgtt gagaaagaca aaacgtcaac
     3421 gaacaccaga agtcactgct cagatggaat attttgcgaa aaaccaacga ttcatccaac
     3481 caaaaatcta tctatttatt tggaagcaat attgtcgcta tggttttaca gaagggttct
     3541 tcgacagcat tcctcggata gtcagaaatg gttttttaaa agtattgcgt aaagaacgag
     3601 aagctataca atctgctgat aagaaagacc gtacagtctc aaaagaaaaa tggcaactag
     3661 tagtgaaaga tatccaatct ggaaatgtgc aagagacaat cgacaaatgg aaaggaaaac
     3721 attatcgttt tactgaagct cagaaacaag cgttggaata ttatcagaag ttagaagaat
     3781 cactgcgttt caatgatgag gcaagaaagt atctgaagga attactataa aaaacatact
     3841 aagattagag gggaacatca ttgacgaatg atgttctcct ctattttcta tttttagatt
     3901 atagtgaaga gtgaaagaaa gttcgaacaa agccttgagg actacgagtc cctatcaaaa
     3961 accgaacttc tttactgtca ttttagaatc aggtttacgt atgttggggc catgagcccg
     4021 tgtataggaa attggaatcg aaatgaagca gtaaagttct ttcaaaactt aaaaaggagg
     4081 aaaacaaatg ccttacattc ttgcattaga tgtttcaatg ggacacagct acagtgtcct
     4141 atacaaagac gacac
//
LOCUS       DAFLWQ010000149         4128 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.154, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000149 DAFLWQ010000000
VERSION     DAFLWQ010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4128
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.154"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(237..1742)
                     /locus_tag="L1V16_002895"
     CDS             complement(237..1742)
                     /locus_tag="L1V16_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1277163.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(1739..2425)
                     /locus_tag="L1V16_002896"
     CDS             complement(1739..2425)
                     /locus_tag="L1V16_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1277164.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2618..4039)
                     /gene="gndA"
                     /locus_tag="L1V16_002897"
     CDS             complement(2618..4039)
                     /gene="gndA"
                     /locus_tag="L1V16_002897"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBN1277165.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1142 a          865 c          697 g         1424 t
ORIGIN      
        1 tttataaaat tgcaatagaa aattccctat ttttatttat tatttttaaa cacgaatatt
       61 acagcatttt attgtttttt cgttcatcta aaagatactt acatttaatt aacggatgtt
      121 attctattta attgttcgct agttttttta taatgacatc cctgaatttc tcacttgctt
      181 gtattttgta ccttattctt tgttggatat ataaaaaaac aagtaaagca catgctttac
      241 ttgtcttctg cctttgcgat aggaataaag attctaaaaa ttgtcccttg ccctactaca
      301 ctttctgcta agatacgtcc tttatagttt tcaaccagtt gtttagcgat agacaacccc
      361 agaccatttc cacccttcgt tctagctctt gctttatcca ctcgataaaa acgattgaag
      421 atcttattaa ggtcttcttt gggtattcct tcgccaaagt cctgaatcgc gatctcaaat
      481 tcattcagag tggaagaaat agagatatgg acttcttttc gtgtagttga atactttact
      541 gcgttatcca atatgataat gattaattgt tcaaagtgat tacgataaat ttgcagggtc
      601 acttcttttg tcaaatcatc atctaaagtg atcacatagt ctggatataa tatcttgaaa
      661 ttattataaa cttgataggt gacttctttt cctttagttg tttcattcgc ataatgaaca
      721 tctacttgtt ctgctcttga taagtctagc atctcttgaa ctaagctttt catacggctg
      781 atttcttgca tgctggcgct taatgattct tctaatatct caggatcatc tttcccccaa
      841 cgatttagca gactaagatg cccttcaata attgcaacag gtgtccttaa ctcatgagat
      901 acgtcttcca cgaattgctc ttgttgttca atatacaaac gcatacggtc aagcatctca
      961 ttgaatattt cagctaaatc tgccaattca tcatttgtgt cgatttcagg catgtggata
     1021 tctgattgcg gatctttacg tatagtatcc attgtatctc tgagtacctt gagtggtttt
     1081 aagaaataag aagataaaaa gaaacctaaa atactactta agatcaaaga aacaacttct
     1141 aaaacaataa gagtcaataa tagcttattt cgaatatcat agaaagaaga taattcatag
     1201 aagctttgcg catagccgat cttttctctt gtacctttag aatatatagg ctggatagat
     1261 aaaaagccag tttttccttc tagtgtaacg atcgttggaa ctttacgtgt agtctgaatc
     1321 aggtttcgac tgttttcatg ggttttaaaa atcaagttct cgtccaaatc ataaacataa
     1381 agatccattg atggctgccc tagctcagct ataaaggaat cgatcttcat taagtttcct
     1441 tcgaccagtg aagtatgatc tacgacctca tctccgtcat ttgtcgcttt cgtcagatta
     1501 cgatacgtat ttactaatgt cagttcttca tccgagttag ccaaacgaga agctacttct
     1561 gaaatcgtac gctctacatt gtttctttct tttgccacaa tcagattgat agatgattta
     1621 taggtaatga cagcgaaaat tgtaaacaca acgaatatga agaaagaact cgcaaaggcc
     1681 cacttgattg tcaaggaggg ccctttcagt tctctttttt ccgatttttt cggctttatc
     1741 acgagcgcat cacataacct gttccgcgta cagtttggat atagctttcc tccccgggaa
     1801 cgtcaatttt gttgcgaaga taacgaatat atacgtccac tacgtttgtt tcaacttctg
     1861 tttcgtatcc ccacacttta tttagtaaaa cgtcacgtgc taataccacg ttcacgtttt
     1921 ccattaaagt aagcagcaac tcgtattctc tttttgttag ttcaattact tcatttccgc
     1981 gacgtacgac acggttttct ttttcgatag tcaaatcgcg ataagtaata gtagtttgtt
     2041 tagccacatt tttatcgcct tcaatatcga ttcgacgcaa caatgcacga agacgtgcta
     2101 ataattcttc gatagcaaat ggtttgacga tgtagtcatc tgctccgtgg tcaagtccag
     2161 atacacgatc gatcacagaa tctcttgcag tcatcataat gattggtgta tttttgactt
     2221 ggcgtacacg tctgcagact tctaaaccgt tcaattctgg gagcatcaga tccaacaata
     2281 tggcatccca ctcattattt aatgccgcat ctaaaccagt tcggccgttg tagtggactt
     2341 ctgcgttata cccttcatgc ttcaactcta gctcgacaaa tcgtgccaag ttcttttcat
     2401 cttcaatgat tagaatattg ctcatttatt attttatcct ttctattcta ctggcttttt
     2461 aaaaactcta tcattatacc gataatatgc ttaaaaatct atagtcattt tatcatggat
     2521 agcaatttta aaaaagagct gaagtctact cataacaatc gacttcagct ctttcgtcct
     2581 ctttttattt tctcatttcc taacagccga aagactatta ttcttcatgg taccatgagt
     2641 aatggaagat tccttctttg tcgacacgct cataggtatg tgcgccaaag taatcgcgtt
     2701 gggcttggat tatatttgca ggcagacgtt ctgctctgta tgaatcgaag taagcgatgg
     2761 ctgatgagaa agtcggtaca ggtacgccag cttggacagc caaggcaacg acgtctctga
     2821 ctgattgctg atattttttc gtgatttcaa cgaagtaatc atctagcaat aaattttcga
     2881 tctcaggatt tttgtcatag gcatccgtaa ttttttgcaa gaatcgagct cggatgatac
     2941 atccagcgcg ccagattttt gcgatttcac caaatggcaa gtcccaatca aattcttttg
     3001 aagcgacacg taattgagca aatccttggg cataactcat gattttactg aaatacaacg
     3061 cttctcggat tttttcgacc aattcttttt tgtctcccgt gaactcaaaa tcgttcgtac
     3121 gagacaaaat cttgcttgct tgtacgcgtt cttctttata agcagaaata tagcgggcaa
     3181 atacagattc agtgatcaat ggaagtggca cacctaagtc aagcgcgctt tggcttgtcc
     3241 atttacctgt tcctttattc ccagctgcat caaggatcac atctactact ggtttacctg
     3301 ttccttcatc gtctttacgt gtcagaatgt cagcagtgat ttctatcaaa tagctgtcta
     3361 attcgccttg attccattct ttaaagatat cagccatttc ttctactgaa aggtttaaaa
     3421 tattcttcat taagtcataa gattcagcaa tcagttgcat atctccatac tcaataccgt
     3481 tgtgtaccat tttcacataa tgtccggctc catttgggcc aatatatgtg acacatggtg
     3541 ctccgtcttc tgcttttgca gaaatttgct ctaagattgg tgcaactagc gcataggctt
     3601 ctttttgtcc accaggcatg attgaaggtc cttttaaagc tccttcttca ccaccggaaa
     3661 cgcctgtacc gataaagttg atgccagagt tggctaactc ttcattacga cgcatcgtat
     3721 ctttaaagaa tgtatttcct ccgtcaatca aaatatcgcc tttatcaagg tgaggaagta
     3781 actcttggat tgttgcatct gttgccggtc ctgctttgac cattagcaag atccgacgtg
     3841 gtttctcgat agattctaca aattcttcga ttgtatatgt tgctttgaaa tttttatctg
     3901 ggtgttcttc tactacagcg gttgttttag cccctgtacg attgaataaa gccactgaat
     3961 agccgcggct ttctatgttc aaggctagat ttttacccat aacggccata ccgacaacgc
     4021 cgatttgttg ttttgacata tgaactcctc ctacatacgg gatttctccc taatctctta
     4081 cattatagct taacacggct acattgcaaa ctaaagaaca acatattt
//
LOCUS       DAFLWQ010000150         4093 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.155, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000150 DAFLWQ010000000
VERSION     DAFLWQ010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4093
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.155"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..153)
                     /locus_tag="L1V16_002898"
     CDS             complement(<1..153)
                     /locus_tag="L1V16_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBN1277166.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWV"
     gene            complement(475..696)
                     /locus_tag="L1V16_002899"
     CDS             complement(475..696)
                     /locus_tag="L1V16_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277167.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(794..1039)
                     /locus_tag="L1V16_002900"
     CDS             complement(794..1039)
                     /locus_tag="L1V16_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277168.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            1279..1893
                     /locus_tag="L1V16_002901"
                     /pseudo
     CDS             1279..1893
                     /locus_tag="L1V16_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(2263..3264)
                     /locus_tag="L1V16_002902"
     CDS             complement(2263..3264)
                     /locus_tag="L1V16_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HBN1277169.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPFSNLDESDLPF"
     gene            complement(3423..3689)
                     /locus_tag="L1V16_002903"
     CDS             complement(3423..3689)
                     /locus_tag="L1V16_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1277170.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(3679..4035)
                     /locus_tag="L1V16_002904"
     CDS             complement(3679..4035)
                     /locus_tag="L1V16_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBN1277171.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
BASE COUNT         1296 a          744 c          541 g         1512 t
ORIGIN      
        1 tacccaacga taaatcgtag tatgacaaac atttattcca cgatcatata acaattcctg
       61 aacttcacga tagcttagat tgtaacgcag gtagtaacca acagcgacaa taatgacgtc
      121 ttttttgaat tgtttgcctt taaaatgatt cattactctg tcctctctgt cttttttctc
      181 aattttacac taaaatagat tttttggaaa actttgcaac agaaccgttt ttactatata
      241 cttcttccca gaacttgtcc gtctccttca aattatctct acctctcgag ttcattgggt
      301 ggtttgccca tttattaaac atggaatcac ctttctcata ctcatatatt tatgtcctat
      361 ttcaattata tttatatatg cttaaataaa tttgtatcct gaaatttatt gtaatatgaa
      421 gctgtatttt acatatagta accaaagagt taataaaata aaaagagcga accattatag
      481 atcagctctt ttttcattgc tgtttttaat cttatctaga atcacttcaa atgtttcaaa
      541 ggtatttaca tctaactgac ataaccaaag caagtacttc ttttctttgt aagtccaatc
      601 aatattacgg taagaggaca ttagattatg gtaccttgct ctttgttcaa ctgaagccaa
      661 ttcccagcgt ttttcaaata ttttttcttc ttccattatt gatccctcgc aagacgctac
      721 ctcaaactta aataatgggc agcgaaagtc taattcctta gatctaagta tagcaaacaa
      781 atatgaaaaa aacttagaag gtagtaaaag ttcttccgtc ttttgctttg cttctattct
      841 taatgtgttt cgttatcggt gccctacaaa gattttcatt aattacacac tcatttattg
      901 ttgtgtattt tctgacattt ctctcttgat caattatttt aattccatgg gcatcctgat
      961 agttcatagg agaggagcgg ctatcagaaa tagttgcacc tatctcttga acttctttta
     1021 caacttctgg aaaatccatc catcctgctt cagctgtcaa aagtaataat ctataatatt
     1081 tatctttcct tttcaatcta agaaatcgtc accccattct ttttcttcta ttataaacta
     1141 tttaactttt agaattcaaa aaccgtttgt ctatttagag tttaccctaa atagacaaaa
     1201 atataacatt gaaaaattta gagttctaac gtatgattag ggtgtattat aaacgttata
     1261 gaaaagtagg gaataaattt gaaaattgct tatattagag tttcatccat cgatcaaaat
     1321 gaacaacgtc aaattgaaga aatgaaaaag tttggcgctg aaaaaatttt tatcgaaaaa
     1381 caatctggag cgacgattag tcatcggccg attttccagg aagctttaga ttttgtcaga
     1441 gagcaagata tttttattgt agaagccatt gatcgacttg gacgcaatta tgacgagatt
     1501 atcgattcag tgaattatct aaagaagaag aatgtgcgac ttattatcac cagtttaccg
     1561 atcatggctg aagcaattgg aaatcctctc ctagataaat tcatcaaaga cttaatcatt
     1621 taaatctcag ccatgattgc tgaacaagaa cgtactgaat cgaaacgacg ccaggcacaa
     1681 ggaattaaaa tcgctaaagc aaacggcgtc tataaaggtc gtcctaagtt atacagtgca
     1741 gacaccaaag atcctcaacg tcgccttgtc tataggagta tcgttcagga tcttgagaat
     1801 ggggttgcta tctcaaagat tgcaacagac tacaatgtga ctaggcaaac aatttaccga
     1861 ataaaaaaag aaatcgacca actaattgta tgatttcttt tttgaatcac gtaattatta
     1921 attagctttg tcatcaatac agacaatcat tttagattca tctagctaag ttgattacat
     1981 ttatgttaaa aagaatttag ttaacataaa tataattgat gcataaatcg tccttattta
     2041 aaggcattta acattgacaa cttagtataa tatatcttat gtaaactaat aagatttgaa
     2101 ttttatttta tacacactcg ataatagatc aattttatgg tcccccgcat ttacgattgc
     2161 acaagagaaa cataaagtcg acctattagc atttcttttc aattcaaaca ttaaaaaagt
     2221 ttatacctct gctactaaaa aatgaaatta tctatttaaa atttaaaacg gtaaatctga
     2281 ttcatccaaa ttggaaaatg gatcagcctg tattggagct ttgtatttct ccataataac
     2341 agatatcttt ttttcatttt ttaaaaaata ccttttaaat ttcttatagt cctctgaaat
     2401 caaaatatag cgtgatggat actcatcaaa agaagaatcg tattcttcct ttaaaattcc
     2461 cgatttactt aatttttcta gtacatcaaa tactctatca ctcaagtaac tccttaaatt
     2521 gttatcactt tcccattgaa ctacttttct ataagttgaa ttatcagttg aaaagataga
     2581 attttcatcc ataaacgcat atattagcag caatctttca tcattgtcaa attctattgg
     2641 atcaaaaata tctaagttgt catcaaaatc tttatcagtt ccggtaactt ttttgttaat
     2701 tactgaaggt gtcttgtaag aaatagaatc taaatcaaag cgttttgatt ctaaattatt
     2761 ttgtgctttc tcaattaaat aattcacttt ttttgtgaga aaccttctga tattgtcttt
     2821 gctatatgtt ccataaaaac ccttatcttc taaagagtcc ctgtacttct taacttctat
     2881 atactcttca gccaaaactt gtggaactgg ttcatctaag aaaaaaaccc ctacctcgcc
     2941 tttgctattt ttataaaagt aatcaatttc tgctatagtt cccgatctat aattatcaac
     3001 tggagaaccc aacttatggc caaaaatcgc taataatata tcactatttt ctacaatttg
     3061 tttattaata acactttgcc cagagctatt atttatataa gtaggaatcg cattcgtttc
     3121 ccatcgaatt ggcatcaaaa ttacttttgt attatctgta ttttctatat tccatctata
     3181 tatggtttct tctacttcat tcctctttgc tgctatatca cctggtgatg ctataaatac
     3241 ttttattaga tttatggttt tcatttattg tacctttctc tttatgtctc tttaaagtaa
     3301 tttttgtata aaatttattg acttttacac tataggacaa cttttatcta tttagtacaa
     3361 aaaggcccac taaactaatt gattagttag gagcctatta caggtatatt ttcaactcgc
     3421 ttttaagcaa attctactac cagctttttg cctaatgccc tagcgatatc atcaagttta
     3481 tcgaaagata cgttatcccc tctctcaatt cgagcaatag tagattgagt tgtatgtgct
     3541 ttttgtgcaa gctccgcttg agttaggcct gcttcctccc gtgcatgata aagagcaacc
     3601 gcagtttcga gttttcttcc ttcacggtca tatgcttctg caaaatcttt gtctttttgc
     3661 ttttcttcaa tcaatttttt aatcatcatt tgtgaaccac tcctctctaa gttcttttgc
     3721 atgtttaagt tcacttattg gtgttttctc cgttttttta gtaaatccat gggtaatgac
     3781 ataccttcca ttgaccacat ggaaatagat agctctttgg atgtttgatc ctaccttact
     3841 tcttaattcg tacaaattag tgtctaattt tttcacccat ttcaaccgtt gagctactag
     3901 catcccattc ttttctgttt cttctattgt acgtaaaagc ttcgcactat ctttttttgg
     3961 taatgtttcc aaccattcta aaaattcatc atgaccatta ggtcttttaa atgtttcaaa
     4021 agatattttt tccataccca attatatcat atattgattt tatattatag tatataacat
     4081 aaaaattcga att
//
LOCUS       DAFLWQ010000151         4066 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.156, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000151 DAFLWQ010000000
VERSION     DAFLWQ010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4066
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.156"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            85..1434
                     /locus_tag="L1V16_002905"
     CDS             85..1434
                     /locus_tag="L1V16_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1277172.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1562..2152)
                     /locus_tag="L1V16_002906"
     CDS             complement(1562..2152)
                     /locus_tag="L1V16_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBN1277173.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2299..3651
                     /gene="brnQ"
                     /locus_tag="L1V16_002907"
     CDS             2299..3651
                     /gene="brnQ"
                     /locus_tag="L1V16_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBN1277174.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1172 a          744 c          789 g         1361 t
ORIGIN      
        1 aaattttgga atcttagttg tgtttttcag aaaactctct taatatggaa gtaattaaac
       61 ttttttagtt aggatgattt aaaaatgaat gaagagcaag aactgcagcg tggactgaaa
      121 aatagacatg tccaactgat ttctattggc ggagcgattg gaacggggtt gtttttaggt
      181 tccggaaagt ctatccagct agctggccct tcgatattgc tcgcctatct tattactgga
      241 tgcatctgtt ttttcattat gcgtgcgtta ggcgaacttc tgttatcaaa caccaataac
      301 cattcttttc tggattttgt tgcagaatat cttggcaaaa aagcggcttt catcactggc
      361 tggacgtatt ggttctgctg ggtatcgatt gcaatggccg atttaacagc catcggaatg
      421 tatgtacgct actgggcgcc tggtgttcct cagtggcttc ctgaactgat tgcattaggt
      481 cttcttcttt gcttgaatat ggtggctgtc tcattgtttg gtgagttaga gttttggttt
      541 gcattgatca aagttgtagc gatcattgcc tttatcctcg taggagctta tatgatcctc
      601 acccactata cgacagatat tggcacagcc agtatcacga atctatggtc tcatggcgga
      661 ttctttccaa ctggtgcaaa aggatttatc ttagctttcc aaatggtaac ctttgctttt
      721 gctgggatag aattagttgg attagtcgct ggagaaacag aaaatcctga aaaagtgttg
      781 ccggaagcta tcaataatat tcctatcagg atcatcttat tttacttagg atctcttttt
      841 gtcattatgg caatctatcc atggaacagc ttgaatccag ataacagtcc atttgtagaa
      901 gtattttcgg aaattgggat cacgattgct gcttccttga tcaatttagt cgtattaagt
      961 gcagcagctt ctgcctgcaa cagtgcaata tatagtacag gacgtatgct tcgttcttta
     1021 gcgcaagaag gcagtgcccc taaaaaattc aaaaagttaa caacacatca tgtgccaggg
     1081 aatgctttga cattttctac tatcgtcatt ttcatttctg ttatcttgaa ttacgtgatg
     1141 cctagtgaag tattcacact agtaagcagt attgccacta cttgtttctt gtttatctgg
     1201 agtatgcttg tctacacgca catgaaatat cgtaaaagta tcctcggcaa aaaagctcat
     1261 tcatttaaaa tgccgttgta cccatttagt aattatctgg tatttcttta catggccttt
     1321 gtgtgtgtcg tcttgttcct aggaaaagat acgagaatcg ctttattact aacacctgtg
     1381 tggttcttgc ttctattact aatctatcat atgaaatatg aacgtaagaa gtaagaaagt
     1441 agttgtgaca gaagtggtca gcttcgagaa ataagaagga atttacgaaa attgcttctt
     1501 aaatttttgt gaaatttcgg cttatttctt ggagataaaa gcttctgtcc cagcctcttt
     1561 tctatttccc cggaaacaac cgctgataat aggcatctgc ttttttatag gaaaaaatcc
     1621 aaataccaga tacaaaaaaa cgtccgaata acccgatcaa cggtacaaaa aagacaccgg
     1681 caatcaagca taagttaatc atcatggaga taagacttcg acggtccttt gacaaaactc
     1741 tcacgacatg ggaatctggt ttatttgctt tcatgatttg cctcatcaag ataccaaaag
     1801 aaaaactcca catcgtgtat actaagacat aagccatctc aggccaaaaa gcttcagggt
     1861 tacgcccgac ccaactagta acagaaggac ataaagtcag ccaaaagagc aaaaagatat
     1921 tcgaccagac cactcggtaa ttaattcgtt ctgccatctg aaatatacga tgatggttca
     1981 cccagatcac cgcaacaaat ataaagctga tggtataagc taataatgta tttcggatga
     2041 cccataaaga atgaaagcta gatgtattag ggatcttgat ctctaataca agaactctca
     2101 aaacaatggc taccactcca tcagtaaatg cttctaatct cgactttgtc acgatgattc
     2161 ctcctcagat gattcagcgc ttttatttta tcacttacgt tattaaataa ccatcgtttt
     2221 atatagggaa ttttctgaaa attgttgcat atttttcgaa attttgttac ttttaaaaaa
     2281 accgtaaagg agttatgtat gacaaaaaaa ttatcattta aagactatct ttttataggc
     2341 tccatgcttt tcggtctatt ttttggtgct ggaaatctta tctttcccgt tcatttgggt
     2401 caagaagcag gcgctgctac cttttgggcg aatctaggtt tcttggttac cggtatcggt
     2461 cttcccttct taggggtgat tgccattggt gtatcgaaaa gctcaggtgt atatgaatta
     2521 gcaaaacgga taaatcaaac atatgcgatg gtttttacca tcttgcttta cttagttatc
     2581 ggaccgtttt ttgctttacc tcgccttgca accacatctt tcgagattgg tttagcacca
     2641 tttatcgatc ctagcagaca gacgctatat ctagcaattt tcagtattgt attttttgtg
     2701 ctggcttggt ggttttcaag aaaaccgaca aagatattag attatgttgg aaagttcctg
     2761 aatcctgcat ttttggtttt attaggtgct ttgcttctcc ttgctttttt gaatccacta
     2821 ggttctgtaa atcaagcgcc tattcagcca aattatcaag agcatgcttt tttcacaggg
     2881 tttactcaag gatataacac attagatgcg cttgctgctt tagcatttgg gatcatcatt
     2941 gtcacaacaa tccaaaacat gggtgtaaca aaacctgctg aaatcgctaa agacacgatc
     3001 aaatctggtg cgatcagcat tatattgatg ggaatcattt atactttgct cgcttattta
     3061 ggtgctatga gcttaggtag ctttgctcta agtgaaaatg gcgggatcac gctggctcag
     3121 attgctgatc attatttagg tacttatggc agtatcttat tagcatttat cgttatatta
     3181 gcttgcttga agaccggtat tggtttgatt acagcttttg cagaaacatt cacagatttg
     3241 tttccgcaaa gaaattacgc attctttgtt gcacttgcta gtatccttcc ttgtttagcg
     3301 gcaaacgtag gcttgacgaa tatcattcaa ttttcgttgc ctgttttgat gttcatctat
     3361 ccattagcaa tgacactgat tttactagtg ttagttggtc ctttgtttaa gcagcgtacg
     3421 gctgtttatc gaatgactac ttattttaca ttgattgctt cgatttttga tgggttgaac
     3481 gcttgcccag aaactatcaa acaaacacct attgttcaaa atcttttata tgttgcggaa
     3541 agctacttgc cgtttttcaa attggggatg gggtggatcg taccagcagt tatcggtttt
     3601 gttatcggac tgatttggag tttcgctaag aaagaagaag tagcagattg ataaaagagg
     3661 ttgtgaaaga gacgttcagc cttgagcaat aaaaagtaat tttgaaaaat ggcttctcac
     3721 atttttgcat aaatttgact taataccgag aaactgactt ttgaacaccg tttattgaga
     3781 ggtcgtgaaa aagccgctta gtttcaagta ttaagaaata ttttgtgaaa atggcttctc
     3841 acatttttgc ataaatttga cttaataccg agaaactggc ttttgaacac cgtttattga
     3901 gcgtctataa actgacctga gtattagaga aacaaaacgg caaagtagct ccatatactt
     3961 tgccgttttg ttttgaacta ataccgaaga gaagctgatc aaacaacatt tcttttataa
     4021 tatagatttt agacatatat atgatataaa aatagttttc gcaaaa
//
LOCUS       DAFLWQ010000152         4060 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.157, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000152 DAFLWQ010000000
VERSION     DAFLWQ010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4060
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.157"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..872)
                     /locus_tag="L1V16_002908"
     CDS             complement(<1..872)
                     /locus_tag="L1V16_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277175.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPL"
     gene            complement(896..1867)
                     /locus_tag="L1V16_002909"
     CDS             complement(896..1867)
                     /locus_tag="L1V16_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBN1277176.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            2572..3951
                     /gene="brnQ"
                     /locus_tag="L1V16_002910"
     CDS             2572..3951
                     /gene="brnQ"
                     /locus_tag="L1V16_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBN1277177.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
BASE COUNT         1088 a          810 c          751 g         1411 t
ORIGIN      
        1 agcggaaaaa tcgaagttgt ttgattagtc agtcctagta attccaattt tttcatagct
       61 gaagcatcga tttgattacc ttcacgaaca atgatttctc cttggaagat catcactggt
      121 tgtacagctt ctcgtgcgga ttgtttcaat tcttctgtct ttttctcatt caatacgtca
      181 ttcactacga taccttgatc cactaagtag cgaatcattt gttgttgtgc tggtgtgaca
      241 ttcaaatatt ggatttgctc ttctgcttct tgtttaaaag cttccaattc actttcacga
      301 acttgtttgc tcatctgttc gtcaatgagc ttcagactct catccctcac agtatggatc
      361 tcagtttcag tcatttcaaa tatcgtcgaa taaaaattgt tcggtagttt ttgataaaac
      421 gcaacatttt ctgcattcac attttcaaaa tttttcttca gcgcggcgat ccgctcttct
      481 gtagtaggct ttgggatatt ttcatcttcc tttgccttat caatcttttc gtcataagat
      541 ttgttgatgg catcattcgt cttatcgatc aattcaaata gttgcttgat ccgattgttc
      601 tggtcatctg caagatcttt ttggtaagtg tattctggag tgactgcttc tgctgccagt
      661 tttctttttt gttcggtttc ttccgtgttc tcgatcgttt tgttcgcacg gatactttct
      721 tctgctactt ggccttctct gaaatcattg gccttttgtt tgacactact aaatgtaacg
      781 ccgcagataa tgataaaaaa caagaacagc aggaaaggca atgctgcctt tccaagtttt
      841 tcttgtagtt tctgcagtgt tttattcaac atgtgcttat cctcctaagc aaagcttatt
      901 cttgatggag atctgccttt tcataagctt tgatgatttc ggcaactaca gggtgccgaa
      961 caacgtcact tgcttcaaaa ttaacaaaat cgattttctt gatttgcttt aatgttcgtt
     1021 ctgcatgaac aagaccactt gttgtccctc gaggcagatc aatctgactc gtatctccat
     1081 tgacaatcat ttttgattga taaccaagac gtgtcaggaa cattttcatc tgagcaactg
     1141 tcgtgttctg tgcttcatcc aaaataacga atgcatcatc caatgtccgc ccccgcatgt
     1201 aagctaaagg agcaatttcg atcacgcctc gttccatcaa tcggttcgta tgatctaatc
     1261 caaaaatttg gtataaagca tcataaacag gacgcagata aggatctact ttttctttta
     1321 gatccccggg aagaaagcct agattttccc ctgcttccac agcaggccgc gtcaaaatga
     1381 ttttttgcac ttcacctttt ttcaaggcag cgattgctaa tactactgca agaaaagttt
     1441 ttcctgtccc ggctggtcct acgccaaata cgatatcatg tttggctacc gattcaacat
     1501 atttcttttg gccgctgttt tttacccgta taggttttcc attacggtct ttgacgatct
     1561 cttcctcata catctcaaca aaataatcta atgtgccttt ttgccccatt ttcagtgccg
     1621 tcacgacatc tggtgtactt acatggattc ctcgtttgat caattcctgc aatgtccgaa
     1681 tgactgaggc agccaaggaa atctgggatt gttcaccaat gatctgaatg atttctccac
     1741 gtgtatggat ggttgtttct gttgtttctt caatcagttt tatatgcttg tcgtgtgcac
     1801 ctaaaagcat gctgacatca tcagcagccg tcaatctaat ctctaaagaa ctagactctt
     1861 ccgtcaaaaa tagacatccc ctttttttcg attcattctt tcctatttta ccatactcag
     1921 aagaaactat atagcaaata agaaaaggtt ctaaaagagt tgcttaacca taagtaccaa
     1981 gaaacgttaa aaaatagctg cttccattct ctaaaggtct cgtttgaata aaaaaagctg
     2041 atcatgtaag ctatgcataa gatagaggac aagtattccg tctaacttag caagtattct
     2101 ctgggtattt ttcttgtttc aaaaaaagaa aacaaaatat ttgaaatatt cttgcatttc
     2161 aaaaaaaaca ggtgtattat aacgtcaaca aattaatata cagcaaagcg tcgaggaaaa
     2221 cagtaggcta ttcagcgatt tattcccagt gagtcatgta agtgagaaat gacaataaat
     2281 cgaatagacg aacatcattt ccgagtcaat gtcgaaaacg tagatcattg tggctgcctc
     2341 cattatcagg ctagcggata actttatcga aaagcgtccg tgaatgaaga agctttttta
     2401 agcgaaaaaa ggtggtaccg ttctagaatc tagagccctt ttcccaagtg gaaaagggct
     2461 ttttttatat tttaaggtgg tggttttcat ggaatctgat attagtggta tttctagttt
     2521 ctgcaacgtt tattttgtta ctcaaaatga taattattgg aggaaaaatt tatggaagaa
     2581 acaaaaactt attcatggaa gcagttattg atggtcagtt cacttatctt cgggatgttc
     2641 ttcgggtcag gtaatctgat ctttcctgtc cacttaggtc aaatggctgg atcaaactgg
     2701 atcagcgctg gtgtaggatt tgccatctca ggcgctcttt tcccattatt agctatctta
     2761 gctgtagtag tgacaaaaag tgatggtctg tatgacttag ctaaacctgt cggaaaatgg
     2821 tatgctgcct tgttcttgat ccttgttcat ttaacgatcg gaccattctt tggtacaccg
     2881 cggacagcag caactgcttt tgaaatggct gctaaaccct ttttgcctga aaaatatgat
     2941 tcattaggta tgtttttatt ctctgctctt ttctttttac ttgcttattt ccttactgta
     3001 catccaacac gtttggtcaa atatgtcgga aagtatttaa actccttgtt tcttgcatta
     3061 ttagctatca tttttgtcgt ttctttattc caacccatgg ggaatctaaa ccaatctgct
     3121 gcagattctt atcagacgaa cgctttgaca aatggcgttt tagaaggata caacacggtt
     3181 gatgcagtag ctttacttgc tttaagtgtc acttttgtcc atgcagttcg tgatcttggt
     3241 tttaaagata aaaaagtcac agaattaaca gcaaaagctg gtagcctgag cgttgcgtta
     3301 gaagtcatga tttattttgg tctggtcctt ctcggtgcga tgagtttgaa taagatgtct
     3361 ttatcagaaa atggcggaac tgcactttct cagatcacta atttttattt aggtaacttc
     3421 ggtgctagct tcttaggggt aatggtcaca ttaggtgtct tcactactgc tatgggactc
     3481 gttgtttctt ttgcacaaga tttccataaa ctgttcccta aagtcagtta tatgacatgg
     3541 ctgcggttaa cgacttttgt ctcttttgtc gttgcgaatg ccggattgga taatatcatc
     3601 caatggtctt taccagtatt gatgcttttg tatccattgt cacttgcgtt aatcttactt
     3661 tccttaacag caaaattctt ccaaaagagt ccatttgtct atcaagtaac gatgttcttt
     3721 tctgccgttc cagccgtatt ggatatgttg gcaaattcgc ctgcattagt gagtcagcaa
     3781 actgtcgtag caagcttact aggattttat catcattatg ttccttttgc tgcattaggt
     3841 cttggctggg tcgtcccaac gttgcttggt tacgctggca gcttgctctt ttattatgta
     3901 tatcgcgtat caggatataa acaagaagca agtgagttac cagaagaata accaaatcaa
     3961 acacaattta acataagaga tattaaacag gaaaaaaaac agctagaaga aagaataaga
     4021 ttctttcttc tagctgtttt ttagttcttt ttttacgaac
//
LOCUS       DAFLWQ010000153         4034 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.158, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000153 DAFLWQ010000000
VERSION     DAFLWQ010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4034
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.158"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            73..234
                     /locus_tag="L1V16_002911"
     CDS             73..234
                     /locus_tag="L1V16_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBN1277178.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            253..1530
                     /locus_tag="L1V16_002912"
     CDS             253..1530
                     /locus_tag="L1V16_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1277179.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1540..2196
                     /locus_tag="L1V16_002913"
     CDS             1540..2196
                     /locus_tag="L1V16_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1277180.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2196..3572
                     /locus_tag="L1V16_002914"
     CDS             2196..3572
                     /locus_tag="L1V16_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1277181.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3702..>4034
                     /locus_tag="L1V16_002915"
     CDS             3702..>4034
                     /locus_tag="L1V16_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBN1277182.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT         1612 a          440 c          704 g         1278 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcagga taaggataag tgtattaatt gtggaaaatg taaaaaagtt
      121 tgccaaatga ataaagattc agttgagaat tgcaatcatc tggagtgtat cagatgtgga
      181 cgatgtaaaa atgcttgtcc agtggatgca attagttatg gagtaagaaa atagagagga
      241 gtagttagga aagtgataaa aaatgctata gcatatatta caagaaagaa aaatagaact
      301 ttaataattt ttatcatatt aactatagtt ctttcttgct tgtattcttg tttaacaata
      361 atgaaatcaa gcaatgaaat agaaaaggct ttatatgaaa gttctaattc ttcaatatca
      421 ataacaaaaa aagatggtaa atattttaat gttaatcaat ttaaagatat tgaaaaatta
      481 aaagaaattg aagaaaaaat aattcaatat gatggattag caaaactaaa agatgctaaa
      541 gtagttagcg gagaacaaag aataaataga gaagatttat ctgacgaatt taagaatgtt
      601 gtttcactcg aagctacaaa taatactaaa agaaatattt tatttagtag tggagtattt
      661 acaattaaag aaggtaaaaa tatagaagaa aatgataaga attcaattat tgttcatgaa
      721 gaatttgcta aacaaaacaa tctaaaatta ggtgatgaag ttgatcttga attactagat
      781 attgaaaaaa gtggaaaaat aaaaagtcat aaatttaaaa ttatagggat cttttctggt
      841 aaaaaacagg aaacatatac aggattatct tctgatttta gtgaaaatat ggtgtttgta
      901 gattattcaa caagccaaga gatattaaat aattcagaaa ataatgaaat tgcaaataaa
      961 attttaatgt attctggtag tgcagaatct acagacttag ccttaaacaa attgaaagag
     1021 cttaaaattg atgagtcaaa gtattttgtt gaaaaagatt ctaatgcgtt tgaagagtct
     1081 ttagagtcag tgagtggaat aaaatatata ataaaagtaa tgacttattc tattatgtta
     1141 ggtgggatgg ttgttctttc attaatcttg attctatggt taagggaaag aatttatgaa
     1201 ataggtatat tcttatctat tggaacatct aagatacaaa ttataatgca atttatattc
     1261 gagttaatat tcatatcgat accaagtata atatcttcct tatttttagg aaatgtatta
     1321 ctaaaagtaa ttgtagatgg attcattaac tcagaggatt caatgatttc cggtggaagt
     1381 ttaataaata atagtagttt tatgtcaaat ataacaacac ttggacaaag ttatttaata
     1441 ttaataagta ttattgtttt atcagttgta tttgcttctt cattaatgtt aatcaagaag
     1501 cctaaagaaa tcttatcaaa aataagttag gagaaaataa tggatatatt agaaataaag
     1561 aatgtagcat atagttatgc aaattctaaa gaaaaagttt tgtcaggagt aaatcaaaaa
     1621 tttgaacttg ggaagtttta tgcgatagta ggaaagtcag gaacaggaaa atctacactt
     1681 ctttccttac ttgctggact tgataaacct caaacaggaa aaatattgtt taagaatgaa
     1741 gatatacaaa ataaaggata tagtaatcat agaaaaaata atatatcttt agtatttcaa
     1801 aactataatt taatagatta tttatcacca attgaaaata ttagattagt aaataaatca
     1861 gcagatgaaa gtatcttgtt tgaactaggt ttagataaaa aacaaataaa aagaaatgtt
     1921 atgaaattat ctggtggaca gcaacaaaga gtagctattg ctagagcatt ggtatcagat
     1981 gctccaataa tactagctga tgagcctact ggtaatctag acagtgttac tgctggagaa
     2041 ataattaata tattaaagac attagctaaa gatagaaata aatgtgtaat agttgtaaca
     2101 catagtaagg aagtagcaga ttctgcggat atcattttag aactaagtgg taaaaagttg
     2161 aaaaaagtaa ataaaatgaa tttggaggtt gaataatgat aaaaaatgca tttgcttatg
     2221 taactagaaa aagtttaaaa tcattaatta tcatattagt tattttatct atgtcaactt
     2281 taagtctcat tagtttatct attaaagatg ctacggacag agcttcaaaa gaaacatttg
     2341 ctaatataac aaatagtttt tctatggaga taaatagaca agtaaatcca ggaacaccta
     2401 gaggtggggg aaatgtaaaa ggtgaagata ttaaaaagat atctcaaaca gatagtatag
     2461 actcctatgt aaaaagaata aacagtgttg cagatttagt tgattatgat attattgaaa
     2521 ctcaagagac tcttgcgaat caatcacctg aaagagcaaa gaattttaaa agaacagtta
     2581 tgttaactgg ggttaacgac tcaacaaaag aaacaaaatt tgtatcagaa gcatataaat
     2641 tagtagaagg aaagcattta gaaaatgaag ataaaaataa aatcttaatg cataaagatt
     2701 tagctgaaaa aaataacctt aaagttggag ataagataaa aataaaatct aatttatttg
     2761 atgctgataa tgagaaaggt gcagatgaaa cagtagaagt agaaattaaa ggtctattcg
     2821 atgggcataa tagcggtgta gtaagtgcag cacaagaact atacgaaaat acattaatca
     2881 ctgatattca tacagctgct aaagtttatg gtaataccga agatacagct gtataccaag
     2941 atgcaacatt ctttgtaaaa ggtgataaga atcttgatag tgtaataaaa gatcttggga
     3001 aattagatat aaattggaga gaatataatt tgattaaaag ttcatcaaat taccctgcat
     3061 tacaacaatc tatatcaggt atttactcaa tttcaaataa attatttttt ggctcattaa
     3121 tatttgcagg agttgtagtt tcattattat tattcttatg gatgaatgct agaaagaaag
     3181 aaatagcagt attactatca ttaggtatat caaaattaga aatttttggt caattcctaa
     3241 ttgagatggt atttatatca atccccgcat tcgttggttc ctatttctta gctcaatata
     3301 cagctgacaa gcttgggaat aatatattga ataaggttac tggtgatata gctaaacaaa
     3361 tagctaaaca atctgcatct agccaattag gtggtggggc agaagctgaa ggatttaaca
     3421 agacattatc aagtttagat atcaatgtat tacctaaatt catgatttat gtagttatat
     3481 ttatgagttt agtacttctt gtatcattga ttatttcttc attcaatata ttaagaagga
     3541 atccaaaaga attattaatt gacaataatt aaaattttcg gtgcttttta gcaccaaaaa
     3601 tgagagtgta atataaaccg tgtaagtaac catcaatcct aggcgggtgg ttgcttcacg
     3661 gtttttattt ttctaaaata agatcaagag gtgattacac gatggctaga aagaaaagaa
     3721 atcctgatgc tgagaagtta gctgaatcca ttttgaatac ttatcaaccc gaatctgtag
     3781 aggatatgca agatgtttta aaagatgtgt ttggtccctt atttgaaaaa atgcttcaag
     3841 gagaattgaa taaccattta gggtatgacg cccattctaa agagccaaag aaacatgaca
     3901 atcgacgaaa cggttatggc aataagacgc ttaaaacgag ctttggtaaa gtaaacattg
     3961 atgttcccag agaccgggag gcttcttttg aacctgagtt gattcctaat agaaaacgag
     4021 atgtctccga catc
//
LOCUS       DAFLWQ010000154         3989 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.159, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000154 DAFLWQ010000000
VERSION     DAFLWQ010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3989
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.159"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            526..2019
                     /locus_tag="L1V16_002916"
     CDS             526..2019
                     /locus_tag="L1V16_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HBN1277183.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            2154..2450
                     /locus_tag="L1V16_002917"
     CDS             2154..2450
                     /locus_tag="L1V16_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBN1277184.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            2551..3402
                     /locus_tag="L1V16_002918"
     CDS             2551..3402
                     /locus_tag="L1V16_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277185.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            3423..3706
                     /locus_tag="L1V16_002919"
                     /pseudo
     CDS             3423..3706
                     /locus_tag="L1V16_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1416 a          577 c          805 g         1191 t
ORIGIN      
        1 taagaattca gactttataa ggaatatagt ggatatacta aatatatttg ctatattcag
       61 tatatcagat atattcaaaa tgtcaaaata tatttgtgcg ttttgcgttg acaatttaga
      121 gtgaaaagag gtaaacttaa ttctatagaa accacagata attcactatt tacaaagtag
      181 caaaagcagt ggtactcttt aaacagaaaa attacataaa aaaaagagac ggaaataatt
      241 gattttagca gaatcaatta tttctgaatc acatggttag gacatgtgtt cacgctcgtc
      301 tcaagaatat gtaagtagct accaactact tatattaaaa gttgatcgga taccttttcc
      361 gattgccttt attctaccaa aaaaaggcga gcaactcaac agaagaacgt ttatttagtg
      421 tacttaaatt aaatattctt aaacactgaa gagagaacac atactatggc tgagattaaa
      481 gctaaactgt gttctctttt tgtttgagaa aggacgttac aatcgatgtt gagcgaaatt
      541 tattcagcta ttcttaaaaa cggcttacgt acatacaaat atcgaaacag caccatgaaa
      601 cctgcaggtc atattgattc cagtaggagt ggtgctatct ttgcgtaccg tagcaagcaa
      661 ttaatgaatg ttgggcgtgg tatggtcatt acttcggaag aagctatttt agagaacgaa
      721 aagaaactaa cgcattggac acctaatacc tatcgctttg gtacttatgc ggatgattat
      781 cgaacagtgg ttaaaggtca ttctgagaaa aacttaagtc aaatcaacac atttgtagtt
      841 gatatcgatt caaaagagaa ccatcaaggc gaaattattt tagcctgttt agatcaagtg
      901 ggctacatgc caacgctaat tttagaatca gatcatggtt atcaagttta ttttgtacta
      961 aagacaccag gctatgtcac aaagaaaagc aatttcaagg tgatcgatgt agcaaaaaaa
     1021 atttcaaaaa caattcgtct acagttggct gaaaaattgt ccggagtgga tctaggatgt
     1081 aaccacttcg gaattgctcg attcccacaa gaaaataata ttgtttttaa agaaatgaac
     1141 tatcagtatt cttttgctga ctggattcaa tggtcgatga agcttgaatc agatcaaaaa
     1201 acaaaagaag atcgagaacg aaaactaatt gtctttcctg agaaaaaaga aattcgtcaa
     1261 gtagatgaac cgtggttcga tatgttactt cataaagcaa acatcgtcgg cggagaagga
     1321 cgtcttggtc gaaataatgt gattttcacg ctttctttag cttattactc ttcaggttat
     1381 gcattggata cttgcgaata caatatgttc acattcaacg aacggttaca ggaaccgcta
     1441 tctgaagcag aattagtaaa gattgtacgt agtgcttatt ctggtaatta tcaagcagca
     1501 agcagagaat tcattattga attgtgccag caatgggttt caccaacctt aaaaaataat
     1561 gatctgttca ttcaacgacg tggctggtgg aaatttaaaa agccacgaga tcaaagaaaa
     1621 tatagtcata aaaatgaatg gaaagaagat ctattggctt atctaagcga aaaaagtctt
     1681 gctagtgagc cttatttgaa cctgtcaaaa aaagaattgg cttcacaact aacgatgccc
     1741 aagcgaacac ttgataagat cttaaatgag ttacgagagg agaataaagt cttctacaag
     1801 gtaacacgag gaagaaatgg cggaatgatc attgcttcag tcaaaacgtt gttcgcgagg
     1861 gttattcaac taagtaaaga aaagagacta gattattcaa caaggatcac agaggtattt
     1921 ggactcaacg agagcttagt agaagagaca tttagacaat tatcaacccc cttgaaccct
     1981 cttaaagaag tgaatctttt tgaagtagat acaggttgaa aaataaaagg tgcaaattgc
     2041 cttatacaat atatctatga tacttctgta ggtgttgctc cctttgccta gctacgtgta
     2101 ggtggtatac ttataactgc gtatgcagtc ttatgtatca tggaggaagt tgtatgtcgt
     2161 taaaaaatta tgtctattca catcctgtta atgtgtttat cattggtcgt ttgggattat
     2221 ctgtggaagt gttctgtgag ctttatggtt ttaagcaggg gactttgtct tcttgggtta
     2281 ccagggaaaa aacagttgct tctttgccga ttgagtttct tcatgggttg tccttagctt
     2341 ctggggagac tatggatcag gtatatgatt gtttgtgtgt gttagagcag gagtatattg
     2401 agtataaaat agctaacgag ttaagaaaaa ggaagaagta tatccagtag tagtttttat
     2461 ttacttaaaa aattggttca ttgagcaacc tatcgctgct aaagtagcaa aggaaaacgt
     2521 taaaggaaag aatttaggga agaaatcgaa atgaaatcgg acgactggat tgaacacacc
     2581 tggcttcctc tgaaaagaaa tagcaaacga aagaaatttt gggtattgca attatggcca
     2641 ttaggaaaac tttgtagtta cggggcacga cttattcttg atttaaccgt ttactcgatt
     2701 ggagtatttg gaacggctta ttacttgata aatgatccca ataggattgc agcatcagac
     2761 atttttacag tgctaatgac gttgattttt gtcatgctat tgtctatttt tactcaatta
     2821 gtcatgcaat ttaccaggca aaaattaaca gcaggaaaac ttttcaaaag cctattcgat
     2881 ttaattgttg taaatgcaat tctagcgact ttaataaaac aaattgaaca atctggaaga
     2941 acaacaaaag gagtgaagga ttttttattg acgtttattc actttgtaaa tggacacatg
     3001 tatttgtttg aagtgggtat tattctcttt tttgtcgggt atgtatccac gaaacttatt
     3061 aaacgttcaa ttgaaaaaga aattgaaatt gacctgattc cgacacttct tggttatgag
     3121 tacaatgttg attttggaag atatgacgaa ttgatcaata cggatatcgt tcacacgagt
     3181 atccatgaat ctactgttaa gggcatcaga tctattttaa aaaatggcca ggaaatgaaa
     3241 gcaatagatc gaagaaaaga gatctacaat ttttatgaag tcgaagcaag cctacgatat
     3301 ggcatcggaa aattgtggtt agatggaagt aatattcgtc aaaacaaacc atacattttt
     3361 tggaacagta gtgatttaga acttccaatg aaagataaat aattatggag aatcgtttga
     3421 aaatgattcc tctatacagg attgtgctta tagttggcat ggagttaaaa accttaaaga
     3481 aggagcagtt attcaaagtg aaagaacgtc ataatcagtt actatgtagt aaaacgggta
     3541 cgatgaacat tgaataccga acagaatatt tagaattaac gaatcaaact gattttttgt
     3601 tgattcgaaa gcaacaagag caagaaaaaa attaatggct acttatagcc aattgattga
     3661 tgaatgggaa caattcaagg aatctaaaat tccagaacgt ctctaaaagc ctttatttgt
     3721 aaagagcata aggaaacgtg ggaacacttt ttaaaaaaag tgttccaata ggctgtgcct
     3781 attacgtttc tcaaaaataa atgtgggaac aaaatattta aaaataggat agtgaaagga
     3841 tagtgaagga tagtaaaagg agggtagtag gatagcaaaa aggataggct ccttttcgct
     3901 atccttttta aattggagga attaatatgg aagtaagaat aagaaatgtg gatgagaaaa
     3961 tcgtaagaga aattgatcga agatgtgac
//
LOCUS       DAFLWQ010000155         3889 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.160, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000155 DAFLWQ010000000
VERSION     DAFLWQ010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3889
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.160"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            179..487
                     /locus_tag="L1V16_002920"
     CDS             179..487
                     /locus_tag="L1V16_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBN1277186.1"
                     /translation="MFQNKGQRYVTKGVMDSLLVELQTLCWNLIDQNVQKKLPLDYLQ
                     IFEFSIEKGNQKLVHRQEEPEARKEYLISPKLRLESVSQKIWVIDSGEYQTMLLPEEY
                     "
     gene            514..813
                     /locus_tag="L1V16_002921"
     CDS             514..813
                     /locus_tag="L1V16_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HBN1277187.1"
                     /translation="MLETAIEVLEKCAQLVTTPEEWGYESVTMEKEEIEMGTLPKNVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVCGLLVEGRLVWSQIGGTNE"
     gene            987..1532
                     /locus_tag="L1V16_002922"
     CDS             987..1532
                     /locus_tag="L1V16_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HBN1277188.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEEKEKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFSRGNDEQSLE
                     ILTTIFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLSDHSLLFQ"
     gene            1688..1984
                     /locus_tag="L1V16_002923"
     CDS             1688..1984
                     /locus_tag="L1V16_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277189.1"
                     /translation="MKVDGECLTSSYKSIYEFFEEKGLDTDLLYQFYIAFRGQQLSFP
                     MKMYDRELVAQKIETMIQENHSIDSRKLTDRYGFSTRWIQSIIRQQQKEQHVHG"
     gene            1977..2867
                     /locus_tag="L1V16_002924"
     CDS             1977..2867
                     /locus_tag="L1V16_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HBN1277190.1"
                     /translation="MANEETVGLRIIEEAFKLPMVKVDRRAFLIQTFQGNVSDIEGLI
                     EKGPQAFLSKEMLDREAQKCIQSITLKSSAVSLATGLPGGIAMAATIPADLLQFFGYS
                     LRLAQEISYIYGFKDLMGETGEFSEEAKNTLILYLGIMLGVTSAGSAVRAMSGKLSTQ
                     ALKKIPQKALTQTLYYPVIKRVLGIFGTKLTKNTFAKGISKAVPVVGGVVSGGINYLS
                     MKPMATKLQTELGKNVAYTEKNLQQDLDILEGEFEEVSSDIVSSDTVLSQLERLSHLL
                     ETNMITEEEFQQLKQELLKK"
     gene            2949..>3889
                     /locus_tag="L1V16_002925"
     CDS             2949..>3889
                     /locus_tag="L1V16_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBN1277191.1"
                     /translation="MKAKRLFLLGTILLLGGCSTVSQNEQKKQVDSTTYETETTRKES
                     STKEIETTTQETKTTESSSKATSSDTSDFQIKQELWDTNKASQLATFVPQWGKTLGQE
                     YKSYNPQNNVSLYGTPLPSAVIDGNWKMAINEAPVTVQWSEDGTGNAGFNLVAVYSDV
                     ETGEYLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFTDIINGQT
                     PQTPVVEESTQQATTTTTQSTSSSGISNWEAAKETVLNNKALWIYESPDKNEANTNII
                     ESTQYRKDLMQDENGEFYPVDISTDDIGNTVMNGGKQ"
BASE COUNT         1444 a          566 c          762 g         1117 t
ORIGIN      
        1 aaaactccat acttttagaa aagcatttct tatatttagt tgtgatgtct attcagttaa
       61 ttgaaataaa taatatagca atgaaataga gataaattca aatatatatt atatccatga
      121 agtccaatct tctttataga agattgggct attttttacg acaaaggagg gaaaagaaat
      181 gtttcaaaat aaaggacaac gttatgtcac aaagggagta atggacagtt tactggtgga
      241 attacaaact ttatgttgga atttaatcga tcaaaacgtt caaaagaagc ttcctttaga
      301 ctatcttcaa atctttgaat tttcgataga aaaaggaaat caaaagttgg ttcatcgtca
      361 agaagaaccg gaagcaagaa aagagtatct gatttcacct aagcttcgtt tggaatcagt
      421 gtctcaaaaa atatgggtca ttgattcggg tgagtatcaa acgatgttat taccagaaga
      481 atactgatat ctaaaagaaa ggagcgaaat gacttgttag aaacggctat cgaagtactg
      541 gaaaagtgtg cacagctagt cactactcct gaagagtggg gctatgaatc cgttacgatg
      601 gaaaaagagg aaattgaaat gggtacgctt cctaaaaatg ttcatctacc acgtttagtg
      661 atgacacatc tttatattta ttgcgcacca gaagatggaa aagactatgt agtttatttc
      721 attacagata ttaccagcca gcgagaattt gtttgtgggt tactggtaga aggacgattg
      781 gtttggagtc agattggagg aacgaatgaa taagatcgat tatttgagaa tgattgcgaa
      841 atgtttagaa gatatcctta ccgcgattta tcgaattctg aagaaaaaag gagaaagaat
      901 atgaaatatt ttcaactagt attgacactt ataacggcaa tggtaattga attgcttgaa
      961 caaaaattag cataggagaa aaagagatga ttgaaaaaga attagtgacc acacaaacag
     1021 aagtttggcg agatcctcat catacccatc gctatgtttt caaacgacaa tgggcaatca
     1081 aaggaaaaga agagaaagaa aaattagcag tagtcattac cattcgtcca acagatacag
     1141 aaccatttac gaatgatttg agtatgttat taatcgaaaa gaatatccga caattgggat
     1201 ttactggttt tattgccgtg aatctttttt cgtatacaaa agcgaaaagt cctcgggtat
     1261 tttctcgtgg caatgatgaa caatctttgg aaatattaac gaccattttt acagaaaaga
     1321 aaatcaacac tattattttt gcttgtggtt cgattacggc aacgagtcaa gtggcttatg
     1381 aacaagcaaa gaccatttac gatcaattga gtgcgaaaca aaagaagatg accaaagtat
     1441 tgataaatgc agaaggcaag ttatctcacc cattaagtat tcatgttcgt aatgaatggc
     1501 aattgtcgga tcattctttg ttatttcaat aaacgaaaat aagtattcaa tgtatatgtt
     1561 tctttttctg ttattttact tgttcttttg cagactaaac aacttgtaaa acctcttgtt
     1621 atatgcatta tcaatgaagg aatcaatatg atatttttaa aatgtcaggg gaaatggagg
     1681 tgagcaagtg aaagtagatg gggaatgttt gacgagttcg tataaaagta tctatgaatt
     1741 ttttgaggaa aaaggactag acacggattt actttatcag ttttatatcg cttttcgtgg
     1801 gcaacagttg tcgtttccaa tgaaaatgta tgaccgagaa ttagtcgctc aaaaaattga
     1861 aacaatgata caagaaaacc attccattga ttctaggaaa ttaacggatc ggtatggttt
     1921 ttcaacgaga tggattcaaa gtattatcag acaacaacaa aaggagcaac atgtacatgg
     1981 ctaatgaaga aacagtaggt ttgagaatca tagaagaagc attcaaatta ccaatggtca
     2041 aagttgatcg tcgagcattt ttgattcaaa catttcaagg gaatgtttct gatattgaag
     2101 gactcataga aaagggtcca caagcatttt tatccaaaga aatgctagat cgtgaagcac
     2161 aaaaatgtat tcaatcgatt accttgaaat caagtgcggt atcgttagca actggactgc
     2221 caggaggtat cgctatggca gcaactattc cagcggatct ccttcagttc tttggttatt
     2281 cattacgatt agcacaggaa atttcgtata tttatggatt taaggattta atgggagaga
     2341 ctggagagtt cagtgaagaa gcaaagaata cgctgatatt gtatttggga attatgcttg
     2401 gagtaacttc tgcaggttct gccgtacgag cgatgtctgg aaagctgtct acacaagcat
     2461 tgaaaaagat tcctcaaaaa gcattgacac aaacgctgta ttatccagta atcaaacgag
     2521 tactaggtat ttttggtaca aagttaacta aaaatacctt tgcgaaaggt atttctaaag
     2581 cagtaccagt tgtgggaggc gttgtttcag gaggcatcaa ttacttgtct atgaaaccaa
     2641 tggcaacgaa gcttcaaaca gagttaggga aaaatgtagc gtatacagaa aaaaatctcc
     2701 aacaagattt agatatttta gaaggtgaat ttgaagaagt atcttctgat atcgtgtctt
     2761 ctgatacagt tctttctcaa ttagaaagac tttctcactt gttggaaacg aatatgatta
     2821 cagaagaaga gtttcaacaa ttgaagcaag agctgttaaa gaaataatta tttagaaaaa
     2881 gcaaccactt atacgggtgg ttctttttct tgaatgaatt caaatttatt attaggagaa
     2941 gaaaaaggat gaaagcaaaa cgattattcc tattaggcac gattctttta cttggaggat
     3001 gttctactgt ctctcaaaat gaacaaaaga aacaagtgga ttcaacaact tatgaaactg
     3061 aaacaacaag aaaggaatct tctacaaaag aaatagaaac aactactcaa gaaactaaaa
     3121 caacagagtc ttctagtaag gcaacgagtt cagatacgag tgattttcaa ataaaacaag
     3181 aattatggga tacaaataaa gcatctcaat tagcaacttt tgtcccacaa tggggaaaga
     3241 cattaggtca agaatataaa agctacaatc ctcagaacaa tgtaagtctg tatggtacgc
     3301 ctttaccaag tgcagttatt gatggaaatt ggaaaatggc aatcaatgaa gcaccagtta
     3361 ctgtacaatg gtcagaagat ggaactggaa atgcaggatt taatttagta gcagtttatt
     3421 ctgatgtaga aactggagaa tatttagggc agcatgttta ctttttcggt tttcaaaatg
     3481 gacaacctaa agtttattta acgcaacaaa atcaaggtaa tgaaaataat tatctgtact
     3541 ttaacgaaac tcaaaatcaa cagctaaaac aaggatttac agatatcatt aatggacaaa
     3601 ctccccaaac accagtagta gaagaatcta ctcaacaagc aacaactaca acgacacaat
     3661 ctacaagtag ttcaggaatt tcaaattggg aagctgctaa agaaactgta ctaaataata
     3721 aagcgttatg gatttatgag tctccagata aaaatgaagc aaatactaat attattgaat
     3781 ccacccaata tagaaaagat ttaatgcaag atgaaaatgg agaattttat ccagttgata
     3841 tttctactga tgatattgga aatacggtaa tgaatggagg aaaacaatt
//
LOCUS       DAFLWQ010000156         3677 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.161, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000156 DAFLWQ010000000
VERSION     DAFLWQ010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.161"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..370
                     /locus_tag="L1V16_002926"
     CDS             <1..370
                     /locus_tag="L1V16_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBN1277192.1"
                     /translation="PVIVHPERNAHFREDPNHLLPFLDMGCLAQLTAPSYVGVFGKDI
                     QKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKEFGKEKVVQMKQVAKDLIN
                     GDEINYPIYEEVKKKKFGLF"
     gene            414..1865
                     /locus_tag="L1V16_002927"
     CDS             414..1865
                     /locus_tag="L1V16_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBN1277193.1"
                     /translation="MYRKNSSGWSKHIDFILLDLFCVQLAFYISYVMRQGDWNPYVIP
                     IYRHMAIFIELENLTIIFLFEAYKNVLKRGYYKEAVASIKQSFMLLLVCSLYLITMQD
                     GNDYSRVSLFIMGVVYGLLTYIIRILWKGLLHHRMKNGEDVSLVIVTSQKIAKNVVRN
                     LKEKNYGMYKLSGVIVVDRDMYGTTIGGVPVVANADNAAEYLLQNWVDEVFINVDESV
                     PYPKELIARCSEMGLAVHMNLTKVSDSTRGKQFIGRVGDYTVITSSINVMTMRQAFIK
                     RTIDILAGIIGCIATGVIFIFVAPVIYIKSPGPIFFAQERIGQNGKTFKMYKFRSMYM
                     DAEERKAELMKENKMSNNLMFKMDFDPRIIGNKILPDGTKKTGIGQFIRSTSLDEFPQ
                     FYNVLMGKMSLVGFRPCLKSEYEKYDFHHRARIAMKPGITGMWQVSGRSDITDFEEVV
                     KLDAEYIRNWSMGLDFRILFRTVKTVLHRNGSM"
     gene            1897..3033
                     /locus_tag="L1V16_002928"
     CDS             1897..3033
                     /locus_tag="L1V16_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBN1277194.1"
                     /translation="MARKKLKICMLGHKRIPSREGGIEIVVEELATRMVALGHEVTCY
                     NRSGHHVSGKEFDQHKNKEYKGVKLKTIFTLNIKGIAAMSSSVFGGIRAAFGKYDIVH
                     FHAEGPCAMLWLPKLFGKRCVATIHGLDHQREKWNKLASTYIMLGEKCAVKFADEIIV
                     LSESVQNYFEDIYGRKTRFIPNGVKKIEIKSAGLITEKYGLTKDSYILFLGRLVPEKG
                     IRYLIEAFKDVQTDKKLIIAGGSSDTDEFANELKELAKGDERIIFTGFVQGQELEELY
                     SNAYIYTLPSDLEGMPLSLLEAMSYGNCCIVSNISECTEVVEDKAMIFKKSDVSDLKI
                     RLEEACNQSEMVKVLKNQATEFICSKYNWDKIVQETLNLYRGNI"
     gene            3033..>3677
                     /locus_tag="L1V16_002929"
     CDS             3033..>3677
                     /locus_tag="L1V16_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1277195.1"
                     /translation="MIRILQCVNDMHRAGLETMLMNYYRNIDRTKIQFDFLTHRPYKS
                     DYDEEIISLGGKVYYAPRLYPQNYPKYFKWMEQFFKDHPEYEIVHSHIDAMSYLPLKA
                     AKKAGIPIRIAHSHNTSIDRDFKYLLKQYYRCKLTSVLTHEFSCGKVAGDFLFRNDKF
                     TLIPNAVDAKKFYYDESIRNDVRMKLGISSQTFVMGHIGRISYSKNHRFLIEIFK"
BASE COUNT         1295 a          448 c          798 g         1136 t
ORIGIN      
        1 accagtgatc gtccatccag aacgcaacgc gcattttcga gaagacccaa atcatttgct
       61 tccgttccta gatatgggat gtttggccca acttactgcg ccaagttatg ttggtgtatt
      121 tggcaaagat atccagaaaa cagccaaaac aatggtcaaa cataatctcg tgcagatggc
      181 tgcttctgat gcacacgggg tctctaagcg caccttttac ttaaaagagt gctatgagca
      241 gattgccaag gagtttggta aggaaaaagt agtacagatg aaacaagtcg caaaggatct
      301 gatcaacggg gatgagatca attatccaat ctatgaagag gtaaaaaaga agaagtttgg
      361 tttattttag ttctttattc gtagataaaa aggaaatgag gagagagtga gagatgtata
      421 gaaaaaactc aagtggttgg tctaaacata ttgattttat tttattagac ttattttgtg
      481 tccagcttgc tttttatata tcatatgtaa tgcgacaggg tgactggaat ccgtatgtga
      541 ttcctattta tcgccacatg gcaattttta tagaacttga gaatcttacg attatatttt
      601 tatttgaggc atataaaaat gttttaaaaa gaggatatta taaagaggct gtagcttcta
      661 taaagcaatc ttttatgctg ttacttgtgt gcagtttata ccttattaca atgcaggatg
      721 gaaatgatta ttccagagtt tctttattta taatgggggt ggtgtatgga ttattaacat
      781 atataattcg tatactttgg aaagggttgt tgcatcaccg catgaaaaac ggtgaagatg
      841 tatcgttagt tattgtaaca tctcaaaaga ttgcaaaaaa tgtagttcgt aatcttaaag
      901 agaagaatta tggcatgtat aaacttagtg gtgtgattgt agtagacaga gatatgtatg
      961 gaactaccat cggaggtgtc ccagtagttg caaatgctga taatgcagcg gaatatcttt
     1021 tacagaattg ggtagatgaa gtattcatca atgttgacga aagtgttcca tatcccaaag
     1081 aattaatcgc cagatgttcg gaaatgggac ttgctgtaca tatgaatctt acaaaagtgt
     1141 ctgatagtac acgtggaaaa caatttattg gccgagttgg tgattatact gttattacat
     1201 ctagtattaa tgttatgacg atgaggcaag catttataaa gagaacgatt gacattcttg
     1261 ctggaattat tggatgtatt gcaacaggtg ttatttttat cttcgtagca ccagttattt
     1321 acatcaaatc accagggccg attttctttg cacaagaacg tattggtcaa aatggtaaga
     1381 catttaagat gtataagttc cgtagtatgt atatggatgc agaagaacgc aaagcagagt
     1441 tgatgaaaga aaataagatg agtaataatc tcatgtttaa gatggatttt gacccaagaa
     1501 tcattggcaa taaaatactt cctgatggaa caaagaagac aggaattgga caatttattc
     1561 gatctacatc attggatgag tttccacaat tttataatgt cctaatggga aaaatgagcc
     1621 tggtggggtt tagaccttgc ttgaagtcag aatatgagaa gtatgatttt catcatcgtg
     1681 cgagaattgc gatgaaacct gggattactg gaatgtggca ggtgagtggt agaagtgata
     1741 tcacagactt cgaagaggtt gtaaaacttg atgcagaata tatcaggaat tggagtatgg
     1801 gattagattt tagaattttg tttaggacag tcaaaactgt gcttcataga aacggttcca
     1861 tgtaagataa agatactata gaaggagtaa aacgtgatgg caagaaaaaa attaaaaatc
     1921 tgtatgctag gtcataaaag aattccatca agagaaggtg gaattgagat agtggtagaa
     1981 gaattggcaa cgcgaatggt tgcacttggg catgaagtga cttgctataa tcgaagtggt
     2041 catcatgtta gcggaaagga atttgaccag cataaaaata aagaatataa aggtgtaaaa
     2101 ttaaagacta tttttacatt aaatataaaa ggaattgcag caatgagttc ttcagtattt
     2161 ggtggaatta gagcagcatt cggaaaatat gatattgttc attttcatgc agaaggacca
     2221 tgtgctatgt tgtggttgcc aaaacttttt gggaaaagat gtgttgcaac aattcatggt
     2281 ctagatcatc aaagagaaaa atggaacaag cttgctagta catacatcat gttaggggaa
     2341 aagtgtgctg taaaatttgc agatgaaata attgtactta gtgaaagcgt ccaaaattat
     2401 tttgaagata tatatggaag aaaaacaagg tttataccaa atggcgttaa aaaaattgaa
     2461 ataaaatcag caggattgat tacagaaaag tatggattaa caaaagattc ttatattttg
     2521 tttttggggc gattggttcc cgaaaaagga attcggtatc taattgaggc atttaaagat
     2581 gttcagacag ataaaaaact tataatagcc ggaggaagct ctgatacaga tgaatttgca
     2641 aatgaactaa aggaattagc aaaaggtgat gagcgaatta tatttactgg atttgtacaa
     2701 ggacaggaat tagaagaatt atatagtaat gcgtatatct atacacttcc aagtgattta
     2761 gaaggaatgc cattaagttt gttagaagca atgagttatg ggaactgttg tatagtttca
     2821 aatatctcag agtgtacgga agtagtagaa gacaaggcta tgatttttaa gaaatcggat
     2881 gtaagtgatt taaagataag attagaagag gcatgcaatc aatcggaaat ggttaaagtt
     2941 ttgaagaatc aagctactga gtttatttgt agtaaatata attgggataa aatcgtacaa
     3001 gaaacattaa atttgtatag gggaaatata taatgattcg aatattacag tgtgtgaatg
     3061 atatgcatcg tgcagggttg gagacgatgc taatgaacta ttataggaat atagatcgaa
     3121 ctaaaattca gtttgatttt ttgacacatc gtccatataa aagtgattat gatgaggaaa
     3181 taataagtct tggaggaaag gtctattatg caccgagact ttatccacaa aattatccta
     3241 aatattttaa atggatggaa caatttttta aggatcatcc agaatatgag attgttcatt
     3301 ctcatattga tgcgatgagt tatttacctt taaaagctgc aaaaaaagct gggattccga
     3361 tacggatagc acatagccat aatacatcga tagatagaga ttttaaatat cttttaaagc
     3421 aatattatcg atgtaagtta acgtctgttt tgacacatga attttcatgt ggaaaagtag
     3481 caggtgattt tttgtttcga aatgataaat tcactttgat tccaaatgca gtggatgcta
     3541 aaaaatttta ttatgatgaa agtattagaa atgatgtacg aatgaaatta ggaatttcaa
     3601 gtcagacgtt tgtaatggga catattggaa gaatttcata ttctaaaaat catcgttttt
     3661 tgattgaaat ttttaaa
//
LOCUS       DAFLWQ010000157         3672 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.162, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000157 DAFLWQ010000000
VERSION     DAFLWQ010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3672
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.162"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            63..878
                     /locus_tag="L1V16_002930"
     CDS             63..878
                     /locus_tag="L1V16_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277196.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            1004..1261
                     /locus_tag="L1V16_002931"
     CDS             1004..1261
                     /locus_tag="L1V16_002931"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277197.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(1513..2085)
                     /locus_tag="L1V16_002932"
     CDS             complement(1513..2085)
                     /locus_tag="L1V16_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1277198.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2101..2706)
                     /locus_tag="L1V16_002933"
     CDS             complement(2101..2706)
                     /locus_tag="L1V16_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HBN1277199.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            complement(3107..>3672)
                     /locus_tag="L1V16_002934"
     CDS             complement(3107..>3672)
                     /locus_tag="L1V16_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBN1277200.1"
                     /translation="YFKSEKDTSSLTLTLEEGVEPDKVTSKVINQLKEKGSLKHLGEY
                     EVLDTAMLTKGIGQILSTITYFITAVAGISLFIAGVGVMNMMYISVSERTKEIGIRRA
                     LGATRKSIMLQFLLEGLILTLSGGLIGYLLGMALAYSVGSLIKVNVSLDLFTILLAVG
                     VSSVIGLVFSVMPASEAAKKDLIDILR"
BASE COUNT         1195 a          700 c          554 g         1223 t
ORIGIN      
        1 tgctggacta caagtaaaaa atactgtatg atcatgacag attcaagaaa ggagcaataa
       61 gattggttaa gatagcagga ctttctaaag gtggaaaaac cgtttcacaa ctttataaac
      121 aaaactacag agactggaga cagttcagaa aaaacattaa ggattcttac tttattctac
      181 caacagaact tgaaaaatat ttaccgaata acaaagctat taatttatat ctgtattact
      241 gttttaaggc aaagaatgaa ggcggggatt cctggcattc ggtcaatacc atagcagagt
      301 ctctaggagt gacaactaaa actataaaca cctggaataa aaccttagtt gatttaggta
      361 tgattgcacg tatagacgat aaccatctca gtaaatcgac aattttactt cctctctcta
      421 gttactataa attagccctt gatagttctt taaaggatgt taccgagagc actgtccatg
      481 aaattgatgg caacttggtt gcagtttatc atttgtttga atggagaaaa aatgaggctg
      541 atgaaaatta taacgttcct tataacacac tctgttgtgt ttttaaaaga aaaacacaaa
      601 aagatactat ctataaattt atcttggtcc aagatgagaa aataagtaat ttcgaattaa
      661 gcactccttc tagtaagatt tatgacgatg catatagatt tgaatgtcaa gatctagaag
      721 ccctcctttc cgcaaataat ctaaacaata tagaacatga aaactttgtt gtaaacacta
      781 gatttaattt agtttctgaa aaggactcag atttgttaga tttgctgata gagcttacta
      841 aaaatctaga taagaaagaa aacattactg tactataact agcatcggtc catcattaag
      901 tttggactat tagaacactt gctattacag aaaaaggtat gctagccacg cttactattt
      961 attggtatca aacaagtatc ttaatttgaa aggaagatga tttatggcta atttatatat
     1021 agagaacaaa ggagacttga atgccattat tactttaatc gtagttatgg taaaatcaat
     1081 aggtaatatc acaataggaa tgctgtttat tatattagca gcagtgctga tttttatgat
     1141 agttatttgg ttcttaaatg aaagatctaa agacaatcaa caccgtaggg atatggagat
     1201 aaaatcaata gagtcaatag attatttatc gataataaca ctaaaaaagc cacgttccta
     1261 aacgtgactt acgctgaacg atatgtgttg tttggtagac gaacaaatcg ttcattataa
     1321 atatatgatg gtatcctaat atagtaagcg tggctagcat acctttaatt actttacctt
     1381 ttacagttac catacacatt ttttgagcag aaatcaagta aataaaaaaa tattatattt
     1441 cacaacatgc taatagactc atatctagaa cgcattaagt atttacctgt ctggttcgct
     1501 gagacttctt ttttaacttt cttcaatttt cttctttatt ctaaaaagcg tactgcgact
     1561 gaaaccggtt atagcttcaa cttccttata cgatttacct gaagtaagca gttcatatgc
     1621 gtgcctcttc ttcggtgtga ttgttgcttt cggacgtcct tctctgaaat taggattatt
     1681 ctttcttgca aacatttttc cttcttgggt acgttccaca atcatatcac gttccatttc
     1741 tgctacactc aacaacgtcc gtgtcaccat tcgccccatg gacgtatttt caatcgttcc
     1801 tagattcaaa accttgatcg ttacgttatc atcgagtaaa ggttcaatga tctctaatgc
     1861 ttctctcgtg ttacgagcaa atcgatcaag cttcgtaaca actatttcat ctccaggctt
     1921 cagaccagcc aacagctgat tgaattttgg ccgatcccgt tttgtacccg taaatttttc
     1981 tgaaaaaata ttcttcttct ctacgccgtt ctcaagcaac tgttgaattt gttcttttgt
     2041 actttgagaa gcggttgaga cacgtgcata tccatatttc gtcatttggt ccacctactt
     2101 ttacaaatca tctatcgtat actcagaata cccttcatag aaatagctga catcgattcc
     2161 tttcatatat aactcgcgat cgtcaatttt atcagtcaga gcattggaaa ttagatagcg
     2221 tatttccaaa tcgtttatgg gacttcgctc cattgcagaa agatagtctg ctttatcgat
     2281 taagttccaa tctacaactt tttgcaattc ttcctttaaa atgagatcca gccaaattct
     2341 agtacttcgg ccatttcctt ctcgaaatgg gtgagcgata ttcatctcca catatttctt
     2401 gataatctct tcaaaagaag tttgtggcat ctgatcaata tgctgtaacg aatgttctaa
     2461 atacataact ggtgcaaatc gaaaatttcc ttttgcaata ttgaccgatc ggatttttcc
     2521 ggcaaaatcg taaatatccg aaaatagaaa ttcatgaatt tcagataaac ctttaaatgt
     2581 accaacttcg atttcattta tttttccaca atcgtacaat tctttcgctt tttgtttact
     2641 gagtttttct tcaaccttag ccaactcaac ttgattggtt aatcccaatt tattctctaa
     2701 aatcatgcga aatctcctta actttatgac ataagtttat gaaacactct caaccccatt
     2761 atatcgcgat tttgtttatg tgtcaaaaac tattaagttt ctgacccccg atagattttt
     2821 caagtgtctc tattttgcac agtctagttg acctttgata cacctctata tttatagaga
     2881 atctaaaaca tcaacatggc atactcaaaa ttctaaatat tagggataaa gaattctcct
     2941 atacaatcaa aaatttcctt tatttcgaac tccggtcacc taactctatt gatctcttac
     3001 aagccaaaga atatctctat actacaaaga aacaataggg tgcctggttg gtctctttgt
     3061 gttttatttt agaatctaga acgtaaatat tcttgtcatt ctgattttat ctaagaatat
     3121 caattaaatc tttttttgca gcctctgaag cgggcattac agaaaagacc agtccaataa
     3181 ccgaagatac cccaaccgct agtaaaatag taaatagatc aagtgacacg tttaccttta
     3241 tcaaagaacc aacactataa gcaagagcca ttcctaataa atagccaatt aaccctcctg
     3301 aaagagttaa aatcaaacct tctaaaagga actgcagcat aatcgatttt cgagtagctc
     3361 ctagggctct tcttataccg atctcttttg ttcgttcaga tacagatata tacatcatgt
     3421 tcattacacc tacccctgcg ataaataaag atatacctgc tacagctgtt ataaaataag
     3481 tgatcgtact gaggatttga ccaattcctt tcgttaacat agccgtatct aacacttcat
     3541 attcccccaa atgtttcaaa ctaccttttt ctttcaattg gtttatcact ttagaggtca
     3601 ccttgtcagg ttcaactcct tcctctaaag ttaacgttag agacgatgta tccttttcag
     3661 acttaaaata at
//
LOCUS       DAFLWQ010000158         3664 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.163, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000158 DAFLWQ010000000
VERSION     DAFLWQ010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.163"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..277
                     /locus_tag="L1V16_002935"
     CDS             <1..277
                     /locus_tag="L1V16_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific recombinase"
                     /protein_id="HBN1277201.1"
                     /translation="ELIKLANKGQDYEHLADEIDELRDKRQLLLVEDASLSGENERIN
                     ELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEEHFVISFKSGIEMEI"
     gene            420..641
                     /locus_tag="L1V16_002936"
     CDS             420..641
                     /locus_tag="L1V16_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1277202.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGNEIKIGN"
     gene            657..1499
                     /locus_tag="L1V16_002937"
     CDS             657..1499
                     /locus_tag="L1V16_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277203.1"
                     /translation="MKIITINDVEYAVFAANEGTSKPQPHIIETKSGTIPEGKQLSLL
                     KEYLKQNDISPIKGATTYWCIDKVLKLDSSKEKTISETIHKQKYLSLTEENIEKQHKF
                     VGASSNYGKEGLIIHDVLNAFPLHNDLNTIAMKIAVIDVTNSTHLSQYKSRLSLYDLA
                     KVILEIPNFDDRLAKGDPQLINIIARNIGAVNMFSFASKYCTYHNVEVCGRDDYSIFD
                     GIVKNTLPHYIQGLTTNKIDTWRRSFDYEAFNECVGKLLDENNIHIPFRRRKLDHFLW
                     YANR"
     gene            1562..3364
                     /locus_tag="L1V16_002938"
     CDS             1562..3364
                     /locus_tag="L1V16_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease"
                     /protein_id="HBN1277204.1"
                     /translation="MGLFDFLKKKQGKVSKHVDYQLASSLFRTGKVFAEKLEVDISNV
                     DEFRKTFIAFDVETTGLNSSSDRIVEIGAVLFKEGVPIQSFGTLVNPKVRIAASASAI
                     NNITNEMLNSAPNEQEVYPQLVEFLGDALDGKITMCAHNASFDFGFLSNTFSRLGYDA
                     KIKYVDTLSLSRKHIKGIVNHKQETVAEYFGLINDTAHRAESDADICGKIFWGVLDII
                     EESLEEQKKQIEKMTPDIKELEACAFIQDIIEKKGCDTSWIRYRKNSNNYVDVTCLYT
                     FLKFKFAKKGNYIIIRKDATNGIDLPIEPCTVSEGGTTNVRVYFRSPFDLTPLSNYIF
                     SAYSDCYNSMNEYMSVSNYTKKEAEQSLSMLKSISKSAMKELLFDAKNRGYDETEVNL
                     NIEKVISREDVIINGLHNRVSLNKIRNIGNWEKGFDAGYPYWERGETARKNGKVDEAI
                     ALFDKARYNGYDAPALYDSYAKAYRKIKDYDNEILILDEGIMRKTRHDVGTLEARRDK
                     AIKLLFAKQEAERIAKEKSDFLKANKKEDAISEPSKKRGRQIIQMTDDGTIIKEFDTI
                     ASAVKEVGVNSKSIRDAANGVQKHAGGYYWKYKD"
     gene            complement(3423..>3664)
                     /locus_tag="L1V16_002939"
     CDS             complement(3423..>3664)
                     /locus_tag="L1V16_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBN1277205.1"
                     /translation="PPRKNMDKSEKLDHSLLGKQRKTVGTVFSSLEKLGCQNFNSRSV
                     KGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1307 a          519 c          746 g         1092 t
ORIGIN      
        1 agaactcatc aagctggcta ataagggtca agattatgaa catctagcag atgagattga
       61 tgagctgaga gacaagcgac agctcctttt agtagaagat gcctccctca gtggcgagaa
      121 cgagcgaatc aatgagctga ttgaatttat ccgcaagaac aaattccgta ccttagagta
      181 cgatgataag cttgtaagga agataatcca gagcgttaca gtctatgaag aacacttcgt
      241 catatccttc aaatctggca tcgaaatgga aatatgaaaa ccagaagtaa atagcccatg
      301 attctacagt agagtcgtgg gttttctttt gcttgctgat tataataata ttttaataac
      361 tattgttatt ataaaccaaa tgatttataa tattcttagc gtaaacttgg aggtgctgta
      421 tgactacggc agaaatgatt aaagaactgt gtgagcaaat gaatataagt gtttccgaac
      481 ttgctagacg tattggacag actccacaga atttcaataa gaaattacaa cgagaaacgg
      541 taaccttaga tgagttgaaa gcgattgctg atgtgctagg tgtcaagttt gtgcaggctt
      601 ttatattgcc tgatggcaat gaaataaaga taggtaatta ggaggtgtaa tttgtattga
      661 aaatcataac aataaatgat gttgagtatg ctgtatttgc tgctaatgaa ggtacttcca
      721 aaccacaacc tcatatcata gaaacgaaat ctggtactat tccagaagga aaacaactga
      781 gtttattaaa agaatatctt aagcagaatg atatttcccc aataaaagga gcaacaacat
      841 attggtgcat tgacaaggtt cttaagcttg attcaagtaa agaaaaaact ataagtgaaa
      901 caatccataa acaaaaatac ttatctttaa ctgaagaaaa tattgagaaa cagcataagt
      961 ttgtaggtgc aagctctaat tatgggaaag aaggtctaat aatacatgat gttttgaatg
     1021 catttcctct tcataatgat ttaaatacta ttgcgatgaa gattgcggta attgatgtaa
     1081 caaattcaac acatctttct caatataaga gcaggttgtc tctatatgat ttggctaaag
     1141 taattctgga gattccaaat tttgatgatc ggttggcaaa aggagatcct cagttgataa
     1201 atattatcgc aaggaacatt ggtgcagtta atatgttctc atttgcatcc aagtactgta
     1261 catatcataa tgtggaagtg tgtgggagag atgattactc catctttgat ggtatcgtta
     1321 aaaatactct tccacactat atccaaggac taactacgaa taagattgat acgtggcgaa
     1381 gaagttttga ttacgaggca tttaacgaat gtgttggaaa actacttgat gaaaataata
     1441 tacatattcc ttttagaaga agaaagttag atcacttctt gtggtatgcg aataggtaga
     1501 atataagaaa aaggcatcgt aaaagtgatt ctggataaaa ttaatggggg aggaaataat
     1561 agtgggatta tttgattttc taaagaaaaa acaaggaaag gttagtaaac acgttgatta
     1621 tcaactggct tctagtctat ttcgtactgg taaagttttt gctgaaaaat tggaagtgga
     1681 catatcaaat gtagatgagt ttcgtaaaac ttttatcgct tttgatgtgg aaacaactgg
     1741 cctaaattct tcttcagata gaattgtaga gattggtgcg gtgctattta aagaaggagt
     1801 tccaattcaa tcattcggaa ctcttgtcaa tccaaaagtt agaattgcag cctcagcttc
     1861 ggcaataaat aatataacta atgaaatgct aaactctgct ccaaatgagc aggaagttta
     1921 cccccagttg gtagaatttt taggagatgc actagatgga aaaatcacta tgtgtgcaca
     1981 caatgcaagt ttcgattttg gatttttaag taacacattt tctagacttg ggtatgatgc
     2041 taaaattaag tatgttgata ctctgagtct ctctagaaaa catataaaag gcattgtaaa
     2101 tcataagcaa gagactgtag cggaatattt cggattaata aatgacactg cccatagagc
     2161 ggaatcagat gcagatatat gcggaaagat tttttggggt gttttagata ttattgagga
     2221 gtcgttggaa gaacaaaaaa agcaaataga aaagatgact ccagacataa aagaacttga
     2281 agcttgtgct tttattcaag atattattga gaaaaaagga tgcgacacca gttggatcag
     2341 gtatcgaaaa aacagtaata attatgtcga tgtaacttgt ctatatacat tcttaaagtt
     2401 taagtttgct aagaagggaa attacatcat tattagaaaa gatgctacaa atggaattga
     2461 tttacctata gaaccttgta ctgtaagtga aggcggtaca acaaatgtgc gagtctattt
     2521 tcgtagcccc tttgacttaa cgcctctttc aaattatatt ttcagtgctt atagcgattg
     2581 ttataattct atgaatgaat atatgagtgt tagtaattac actaaaaaag aagcagagca
     2641 aagccttagt atgctgaaat ctatttcaaa atcagcgatg aaagagttat tattcgatgc
     2701 aaaaaatcgt ggatatgatg agactgaagt taacctaaat attgaaaaag tgatatctag
     2761 agaagatgta attattaacg ggttgcataa tcgagtttca ttaaacaaga tacgaaatat
     2821 agggaattgg gagaaaggat ttgatgcagg ttatccatat tgggaacgtg gagaaactgc
     2881 taggaaaaat ggcaaagtag atgaagctat tgcacttttt gataaagctc gatataacgg
     2941 ctatgatgct cctgcgctat atgattctta tgctaaagct tatcgaaaaa ttaaggatta
     3001 cgataatgaa attctcattc ttgatgaagg aattatgcgt aaaacacggc acgatgttgg
     3061 tactttagag gctcgtaggg ataaggcaat taagctatta tttgctaaac aagaggcaga
     3121 gcggatagct aaggaaaaat ctgattttct aaaagcgaac aaaaaagagg atgcgattag
     3181 tgagcctagc aagaagcgtg gaagacagat tattcaaatg actgatgatg gaacaataat
     3241 aaaagaattc gatactatag cttctgctgt aaaagaagtt ggcgttaact caaaaagtat
     3301 tagggatgct gcaaatggag ttcaaaaaca tgctggagga tactactgga aatacaaaga
     3361 ttagcagata atctaagata acctaggatc ttcttaatag atacccgtgg tgctagttaa
     3421 ttttaatatc ctaaagaata tctcaaagtt ccttcaaaac gtcgttgtgc tcgacttaat
     3481 agaacactgt aagccagtaa tatgctttca aatctactct ctagcccttt aacagaacgt
     3541 gagttgaaat tttgacaacc taatttttct aaggaagaaa aaacagtccc aactgttttt
     3601 ctttgttttc caagtaagct gtggtctagt ttttctgatt tatccatgtt tttacgtggc
     3661 ggaa
//
LOCUS       DAFLWQ010000159         3639 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.164, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000159 DAFLWQ010000000
VERSION     DAFLWQ010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.164"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            69..152
                     /locus_tag="L1V16_002940"
     CDS             69..152
                     /locus_tag="L1V16_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBN1277206.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            277..1014
                     /gene="erm(B)"
                     /locus_tag="L1V16_002941"
     CDS             277..1014
                     /gene="erm(B)"
                     /locus_tag="L1V16_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBN1277207.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1277..2140)
                     /locus_tag="L1V16_002942"
     CDS             complement(1277..2140)
                     /locus_tag="L1V16_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBN1277208.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2142..2414)
                     /locus_tag="L1V16_002943"
     CDS             complement(2142..2414)
                     /locus_tag="L1V16_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBN1277209.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2431..2640)
                     /locus_tag="L1V16_002944"
     CDS             complement(2431..2640)
                     /locus_tag="L1V16_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBN1277210.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            complement(2739..3635)
                     /locus_tag="L1V16_002945"
     CDS             complement(2739..3635)
                     /locus_tag="L1V16_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1277211.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMIERIIQLENEKE"
BASE COUNT         1113 a          643 c          563 g         1320 t
ORIGIN      
        1 ttttgtataa taggaattga agttaaatta gatgctaaaa atttgtaatt aagaaggagg
       61 gattcgtcat gttggtattc caaatgcgta atgtagataa aacatctacc gttttgaaac
      121 agactaaaaa cagtgattac gcagataaat aaatacgtta gattaattcc taccagtgac
      181 taatcttatg actttttaaa cagataacta aaattacaaa caaatcgttt aacttctgta
      241 tttatttata gatgtaatca cttcaggagt gattacatga acaaaaatat aaaatattct
      301 caaaactttt taacgagtga aaaagtactc aaccaaataa taaaacaatt gaatttaaaa
      361 gaaaccgata ccgtttacga aattggaaca ggtaaagggc atttaacgac gaaactggct
      421 aaaataagta aacaggtaac gtctattgaa ttagacagtc atctattcaa cttatcgtca
      481 gaaaaattaa aactgaacac tcgtgtcact ttaattcacc aagatattct acagtttcaa
      541 ttccctaaca aacagaggta taaaattgtt gggaatattc cttaccattt aagcacacaa
      601 attattaaaa aagtggtttt tgaaagccat gcgtctgaca tctatctgat tgttgaagaa
      661 ggattctaca agcgtacctt ggatattcac cgaacactag ggttgctctt gcacactcaa
      721 gtctcgattc agcaattgct taagctgcca gcggaatgct ttcatcctaa accaaaagta
      781 aacagtgtct taataaaact tacccgccat accacagatg ttccagataa atattggaag
      841 ctatatacgt actttgtttc aaaatgggtc aatcgagaat atcgtcaact gtttactaaa
      901 aatcagtttc atcaagcaat gaaacacgcc aaagtaaaca atttaagtac cgttacttat
      961 gagcaagtat tgtctatttt taatagttat ctattattta acgggaggaa ataattctat
     1021 gagtcgcttt tgtaaatttg gaaagttaca cgttactaaa gggaatgtag ataaattatt
     1081 aggtataggg cacctctaat aactaccaat taattcacct caaaatgaaa ttagaaaaaa
     1141 acagcgaaat ttttaaatct atttcttatc gatacaaatt cctcgtaggc gctcgggacc
     1201 ccaacatgag gaaatgtttt tataaaaaaa gagtagttac cgttttttgg taactactct
     1261 tttccttttt taaggtttaa atacctggaa gtttaggtgt tttgggtatt ggtggtgtag
     1321 gtagctgcaa gctttccatt ttttgttgaa ttgctttaaa ttcaggggtt tcttggtgtt
     1381 gattttgaac cattttttgc tctattctct ccaaagtcgg ttgaatttct ttccctgata
     1441 ctttacgatt taattctctt tctaaggtct ctttcggact aatggaaggc gtttctaagc
     1501 ttgaatagag tttcactcct tctctattgt aaagccttat atcgctaaat aagcccgttt
     1561 tatgaagggt ttctaaattg gtcggtaagt ttttgacaac aatatcatgc gcttgttttg
     1621 gtgttgccct agctgtcatt ggatcatctg catacatggt ttcatatcgt tcaatcgttc
     1681 ctaagtatga ttcaattttc ggtactgcca tgacgtatat ttttgtttca taacctttag
     1741 attgaagcat tgtggctgtt tgaatgggaa cgtctgttgt tcgtcctgtt ccttcaatca
     1801 ctaaattata gccttgatcg cttaaacggc taataagtgc ttctgtcatg cgattcgaat
     1861 aaggggtaac gtgttttact acgtcttttt catagagttt cactaattcg tcaaaatttg
     1921 ggtgctgttg tttaaaggta tcattatcaa tgacaataac attcccttgt gtttcttcaa
     1981 aaattgctga tcgcaaactg gttttccctg accctggttg cccaccaagt aaaaaagcgg
     2041 ttggcgattc aaccgctagt ctatttttag ttagtcgttc aacattcttt tctaaacgat
     2101 cttcaaattg cttttcggtg aagtcagtaa tattcgccat gttaagccac tttctcttta
     2161 ttcaaaattt gttttgaata ttgattcatt gaccgccaat actcatgaat agcttgtaat
     2221 tcttcaaatg gttgttgaaa taaatcaact tcttgtgcca cttctaattg atttaaaaga
     2281 ttcacttcta gtaaacgagt atttttagta tctagttcat gattcaaaac ataatttaat
     2341 acccgattat aaacacttgc cgataactca ttaatgattt caatttcaaa tgttttttca
     2401 tacgtaactg ccatttcatt ttcactcctt ttaaagtttg tcaggtaaat atttccgtat
     2461 atattcttct aaggcttgat ccataacttc ttttacgttt ccgccattct ttgctgtttc
     2521 gatttttatg atatggtgca agtcggcacg aacacgaacc gtcttatccc ccattatatc
     2581 tttttttgcg ctgattggcg tatcatttcg ttttgctttc tgtgcgccta aatttcccac
     2641 gatcgctcac ttctttctat ttcttcttac tatttatttt atcatcacct atcacaaatc
     2701 acaagtgatt tgtgattaat cacttgtgat ttgtgattct attctttttc attttctaat
     2761 tgaatgattc gctcaatcat ttcaaaaaat acgttctcat acatagacaa aacttttttg
     2821 tcatagcctt tgtgttctgt aatgccattt ttagaccaag tacttacttt attacttcgc
     2881 ttgataatat ttcggaaaac caaattatcc tctttatgtt ctttgtacag ttcttccagg
     2941 tttgatttta tcgttgcgct gtccgtatca actaaataag gaacaaaacc aatcatatct
     3001 agtccagggt taaactgttc ttgcaaatca atcaaatagg aaatatagtt ttgaatgttg
     3061 tttgtacttt cttcttctgc ttgtaaaggg atcataacgt aatcactcgc cacgattgca
     3121 ttatttgtat aaacgcttgg cgttggtaca gtatcaataa taataagatc atagtcactt
     3181 tttaaaggtg ctaaaagagt agcaagcaat ctactttcat tttcaaacgt ccatgagcga
     3241 gttaattttg gcagtaacat caaatcaaac gtgccaggga tcaagtctaa attatcagtc
     3301 aaatgaataa tagaagaagc caagtttcca tttttcaagc cttcataaaa attgacacgt
     3361 ggcaattcta cctcaaaagt ttttgctaag tcttttgtca atgttgcctg taagtcctta
     3421 tcgatcatta aaacttttaa attcaatttg tctgtcaagt aagcaaacat agtcgataat
     3481 ttggactttc caacaccacc tttaaagtaa ttattcaaga taataattgc ttcattttta
     3541 ttgtttaaaa tacgtcttaa ttcttcaagt atttttagtt tttccttctc cataactacg
     3601 ccccattctt tttttgtata gtaatattgt atcattaag
//
LOCUS       DAFLWQ010000160         3547 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.165, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000160 DAFLWQ010000000
VERSION     DAFLWQ010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3547
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.165"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..2303)
                     /locus_tag="L1V16_002946"
     CDS             complement(<1..2303)
                     /locus_tag="L1V16_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277212.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVET"
     gene            complement(2975..3243)
                     /locus_tag="L1V16_002947"
                     /pseudo
     CDS             complement(2975..3243)
                     /locus_tag="L1V16_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          990 a          788 c          561 g         1208 t
ORIGIN      
        1 gtttctacca gctgatatgc tcctggtgct aaaccgtcaa ttgccagttt tccatcttct
       61 cctgtagtta aaccggtttg tagcgtttct ccttctcggt tctgtaactc aaaaacagct
      121 ccttgaagga cttcaccact gccttcagca tgtttaatta gttcaacacc acccgtatca
      181 aggatgtttt caatggttaa cgtcacttct tctatggagt attcatttat aaaaacatca
      241 tgtaccgtcg catctaaaag atacccttcc ggtgcttctg tttctcggac ttgatagcta
      301 cctacaggaa gcggttcact taaaaattct ccgttttctg ccgttatacc ttcttgtatc
      361 acttgtgaat cgcttgataa aatttcaaat tttgctcctg ccagcctttg gccattctca
      421 tcagttttaa ttactttaat acgcccatcg attttccttg ttcttacagt actcgtattc
      481 aatcgattgt cactattcac aagcgttgca aagtttaaaa tttgatcgcc gaccgcatac
      541 gcctctacat tgaccttaaa agagagggta aaacttgtcg gaccaccaat cgtattattc
      601 gcactgaaac gaactattcc attattgact tcggcatcaa tgaaagaggg aatatctgat
      661 agaaatgaca caaattccat gccttcttcc aaaacatctt caataacaag cgtatttctt
      721 gttccagaaa acatcgagac atgcagagta tacgttagtt cattttcatt gagattgata
      781 acatttttgt ccacactttt tcttaaagag attgccggaa gattactttc agggattctc
      841 aagcggtagt ctcggctcat tacctgatta ttgtaggtca tactcgctcg attccgagaa
      901 aacccatcct cttgtcttcc ttcattgaac aagtcgacat cggtcacttc aagagcatat
      961 tcaataaaat acgattgacc ctctgctaga ttaccaaagt ccacaacaag tgtattcgtt
     1021 tccttattaa aagatacttt gtccacaaat tcctcggaaa cataatgagt tctaacgttt
     1081 gcttcacctg gattcgttac ttctgcgatc cgaaccccac ctgaaatagg ttctctattt
     1141 ccagtggaac tccatgtagt cggattcggt gccaaagttg ttccttgcgg tagtacatcg
     1201 gtaaccacta caccgtcttt tcgtgatcct tcataattta cctgcaaaat aaatttatta
     1261 ctgttggtca cgtcttgccc gtcaatcagc agattcccaa gatttccttg gctgtcgatt
     1321 tctctagagc catagtataa tttcgaaaaa atgggtcttg atgaaggaat aggcgtaatt
     1381 gaaaattccg tgtttgctgc tcgctcagca taagtaagac tcacttgaaa gtcattattt
     1441 ggctcagtac cgcctgattg aaagaaagca acttcaaacg tgatactgaa tgtatacgac
     1501 tgagcggctt catttaatcc ttcataatca aaggtaaatg gaaaaacaac gtctgtgcct
     1561 tcttggtaaa atgccagtgg ctttaaaggt gaatcatcag cgacctccac tctaatgaac
     1621 tcaattaagc caatcgatgc tctaggaact cgtacgacca tctccccata ttcttcaaga
     1681 atatcgccag cgcctccttg aatgtatccc tttaacgttt gtgtatgcct gctcggcaaa
     1741 gtggggcgct cagcagagat gccgatgtca taattcaaga gctcctcttg tctttcaatc
     1801 tgagattcct gcgttataga tggctcagat gatctggctt cattaaaaga ttcacttaag
     1861 ctttcttctg gtatattaaa agattcactt gtgctttctt ctggtacatt aaaagactca
     1921 cttgtgcttt cttctggtac actgatttct attgagaccg tatttgattg aatatcaccg
     1981 cttcttgcgg tcaattcgta tttacctgaa tgctgggaag aataagtaat cagacgttcg
     2041 taatcattga gttgcttcac ttccccttca atcaaatcct cactcttatc aatgaccaat
     2101 gcatttagca ggtctggtgt tcctctgact cgcaactgga actgctcacc caaagcagcc
     2161 tcctcttgat caacttcgat cgtcagcgaa cgctctggct gttctgctaa agactcagct
     2221 agaaccgtta tgttcccaaa ttgattgatc acaataagca taactagaaa catacttaac
     2281 agtttatgaa atttgttcct cactattact cccccttata attttgacta aacaacaagg
     2341 tacccgataa ttttctaaaa agattcccca actcaaaatg gctgcgttac ctccctcgta
     2401 ttttcggttc aactcaagcg ttgcaatgta agctgtaaac aaagctaatg attgccgatt
     2461 gtcttctgtt gattgattcg atagctttgt atgactttta gttgtccgtg tggcttaacc
     2521 ataattatga tttcacgatt cctcctgcca gtgccttgca caagctggag cgtaacccta
     2581 atagttattt tgttaatgta cttatatact tttatacttt tccattagaa acaatcacta
     2641 aatcgttgat accaaggtca gactctagaa tttcatcagt gagtccctgt attggttaac
     2701 cttcatcaat cccaaaaaaa tatatcaatg cttagcatca aaatgaatat atagtttaga
     2761 atacttggga ttcatcgata actgatcgct tatttggcca tattatttgg cacttggttc
     2821 aactaaacgc atttaggatg ttccttcatt ctcgtcatgg atgttctcaa accgtcatta
     2881 ctaataaact gtccaccgaa tcgatggttc atttcttgca ttttccacgt ccaattactc
     2941 tttttgctct ttatttgggc gtagtttcac tttcttaact tgtatcgtct tccatcaact
     3001 ccttaatcat cttcttagct ttattggctc ggtttccttg taaaaggtat ctacaaatag
     3061 tgacaatctg tattaaatct tcatcatttt ctgtaatgtc aataatttct atattctgta
     3121 ccatatattg caaagggttt cactaagttc ataaccgaag cgaattaaac aacttttgta
     3181 tagaataact accttttcta tttttccatt ggtaattcta tctattaatt ggtttaatcc
     3241 ttttgttgta gttgattcca ctaccaagat gattctctcg aattttaaag cttgaagatg
     3301 tattgctatt tttgctaact ggcgtatttg caactatttt tcccttctat tcttccttca
     3361 ttgattcccc tctaaaatta ctatccataa aaaattgcat aaatgacaat agtatttata
     3421 ttagtcatac tgctttttaa cacagcaaat tccagaaaaa cattcgttac atatttgtga
     3481 atttttccaa aaaataacat ttttataaaa cgacgaaaaa taaatcacta ccagtcaact
     3541 tctataa
//
LOCUS       DAFLWQ010000161         3486 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.166, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000161 DAFLWQ010000000
VERSION     DAFLWQ010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.166"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            38..919
                     /locus_tag="L1V16_002948"
     CDS             38..919
                     /locus_tag="L1V16_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1277213.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            932..2542
                     /locus_tag="L1V16_002949"
     CDS             932..2542
                     /locus_tag="L1V16_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HBN1277214.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(2619..3278)
                     /locus_tag="L1V16_002950"
     CDS             complement(2619..3278)
                     /locus_tag="L1V16_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBN1277215.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
BASE COUNT          954 a          677 c          697 g         1158 t
ORIGIN      
        1 tttagtatat atttttagaa aaaggagtgg ggtttttatg gcagaaatcg tcaaagtcac
       61 acatttgaaa aagagctttg gtcgtttcga agctttaaaa gatgtctctt tcaccgtaca
      121 ttcaggtgaa gtcgttggat ttatcggacc aaatggttct ggaaaatcca cgacgattcg
      181 gacactttta gggattataa aaaaagacgg cggaacggca acgatttttg ggcaagatgt
      241 atgggaagat agtttatcta tccatgaacg tctttcttat gttccaggcg atatctcttt
      301 gtggggaaat ttgactggag gagcgatcat cgatctcttc atgaagcttc atggaaaagg
      361 gagtgctcaa aaaaaagatg aactgattca acgtttctct cttgatccta agaaaaaagc
      421 aaaaaactat tcaaaaggaa atcgccaaaa agtgggcttg attgctgctt tggctgttga
      481 ttcggatctc tatttatttg atgagcctac ttctggttta gatcctttga tggaaacgat
      541 tttccaagaa gaagttgaaa aattgaaaga acagggcaaa tccatcctac tttcttctca
      601 tattctcagt gaagtcgagc gactagcgga taaagtcgtg atcatacgcg aaggaacact
      661 cgatgaagaa ggaacactcg atgaattgcg tcatttgact cgttcgacca tcactataga
      721 aacagaagca gagaatagtc acttagcaca attgaacggt gtccatgact ttgtgcaaaa
      781 aggtcacctc gctcaatttg ctgctgataa cgaagctttc gatgtgattt tagctgaagc
      841 gtccaaatta ggtgtgaaaa aatttgaatc tattccaccg actcttgagg atttattcat
      901 gagacattat gaaggatgag gaggaagcga aatgactgat aaattttcac gctggtccac
      961 ccttttttct caaaacctta gccgtgactg gaaaaagatc ctgatatggc tagtcggtgt
     1021 cactgctttt tctggtggtt ttgtccctgc gtttgaagaa ttgacttccg gacaaggatt
     1081 agctggatta tacgaaacct tgcaaaaccc ggcaatgatt gcaatggtcg gaccaactcc
     1141 agcttcgaat gctgctgagt atactttagg agcgatgtat gcaaatgaaa tgttgctttt
     1201 ttgcagtttg tttgctgctg tgatctctgt tttacacgtg gtgagccaaa cgagaaaaaa
     1261 agaagaactt ggtctgattg aacttattcg ttcctttcga gtcggacgtc aagcaaactc
     1321 tttagctgtc atcgctgaaa gtattctgat caatttgctt ttagcaatat cgatcagctg
     1381 tacgatgatt tttttccaag cggattcgat cactgcagaa ggtgcttggc tttttgggct
     1441 atctgtaggt agtatgggga ttttggggag tgccgttgca ctgtttgctg cacaactgat
     1501 gccaagttca gccagttcga atggtctgtc tttagcgttt ttaggtggac tttaccttct
     1561 acgagcaata acagatgtag ctgattcctc cctttcgatg tggaatcctt taggctggtc
     1621 ttatttgacc tatccattta caactaacaa ctggattcct ttgctttatt tgtttttgtt
     1681 cagtctaatc ttgataatca gttcatttgt tttagaggaa catcgagatt tgaacaccgg
     1741 ctatatcccc gaacgtgaag gaaaaccgta tgctaaacgt tctcttttat ccttgcgtgg
     1801 tttattattc tatctaaata aagggatgac aatcagttgg cttatcactt ttggtttgat
     1861 gggggcggca tacggctcta tctacgggaa tatgcaacag tttttagaaa gtaacgactt
     1921 aatgaaacag atgtttatcc aatctggcgt ctcaattgaa aaaaacttta caagcacgat
     1981 catggtagtc ttgatttgtc tagctgctat tttaccaatt gctagcatca atcgtttatt
     2041 tacagaagaa acccacggac gtatgaatca gctgttcgca acaaaaattt ctaggaacca
     2101 actttattgg accaatatgt tactagctat tctatttgct atattggcaa tcctgattag
     2161 ttctggtgca ctagggcttt ctgctttggc ttcgatgaag gatgcgaaag acatggatct
     2221 attgatgttt cttaaagccg ggttcaattt cctgcctgcc gttttagtgt ttatcggaat
     2281 tagtggcttt ctattcggat ggcttcctcg aatcggtaaa cttgcttata tctacttagc
     2341 ttactccttt gcactcaatt actttggcgg aattttggat ttaccagaat ggttttccaa
     2401 aacagctgtc cctagctggg ttccacggat gccaaacgat tcttttgatc tttccgtgtt
     2461 ccttacgtta tcatgtatca gccttgcact gttcgtcctt ggttctattg gttataggcg
     2521 aagagactta ctagaaggat aataaaaaag catgtacaat ttcatgctag cctccaaatc
     2581 tgggtcaaaa atccaacatt tggaggtcat ttttttattt acaagtcttc taactgctct
     2641 ttatcaatga tccagacttc tcgattcttt ctttttacat aaccattctc ctctaataat
     2701 ttaaattttc tagataaagt ttcgggggtc gtaccgataa atgcagcaag ttctttcatt
     2761 ttcattggca ggaaaaagtg atccttccct gtcgctttag ctaagtcaag cagatagaca
     2821 gcgactcgtt cttctacttt ttccatcatc aaaaaagttg tctgctgctg tacttttgtt
     2881 aatttctcaa cgttgattgc taaaagtttc agactaaggg cgggataatg cagtaagagt
     2941 tccgagaaat ctttttgtct caatatgcaa atttccgttt tttctagtgc ttcgccaaat
     3001 aaagactcat ttggaacgcc tagcaactgg ctctctccct catatccgcc cggctctatt
     3061 actcgtaaaa gctgttcctt tccgctagca gataattgat acactttcat actgccggag
     3121 gccacgatca ctaattgagg ttctccattc ggcgcaagaa tctgttctcc tttttccaca
     3181 tagtgatgtt tgacaagtgc gtgtactttt tcttgatctt gctgtactaa gtgattgaac
     3241 aaaggaacaa atgaaacaca taaatgatca tgactcataa tctctcctcc ttctaaacag
     3301 ctatttctaa taaagaaaca taacttccct tattccaact gataattttc ttttatcata
     3361 gcataaacgt caagcgaacc agataccagc aaatagagtg gatttctttt tgtcccttgc
     3421 tttattttcc ttcttttgag accttaagta attgattcct atcaattttt taaatattta
     3481 cttttt
//
LOCUS       DAFLWQ010000162         3449 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.167, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000162 DAFLWQ010000000
VERSION     DAFLWQ010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.167"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(150..1337)
                     /locus_tag="L1V16_002951"
     CDS             complement(150..1337)
                     /locus_tag="L1V16_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HBN1277216.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
     gene            1447..1824
                     /locus_tag="L1V16_002952"
                     /pseudo
     CDS             1447..1824
                     /locus_tag="L1V16_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
     gene            1872..3272
                     /gene="yfcC"
                     /locus_tag="L1V16_002953"
     CDS             1872..3272
                     /gene="yfcC"
                     /locus_tag="L1V16_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBN1277217.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            3305..>3449
                     /locus_tag="L1V16_002954"
     CDS             3305..>3449
                     /locus_tag="L1V16_002954"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277218.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAF"
BASE COUNT          978 a          652 c          684 g         1135 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact tttacacaat tatatggacg
     1441 taatcaaaaa atgtttccac agaggacttc tttaattatt gtcgattaga ggaaagtggt
     1501 gtaacagtca ctagcggtac agatttaccg ctgtttatta ctgatattcc tgaatcgatt
     1561 ataagagcag tattccgtcg ttttcctgaa ggagaagaag tctgggagaa agaaacaagc
     1621 ttcacgacaa ccgagctgct gaaaagtttt acaagcaaca gcttcaaagt aaatggttta
     1681 tcggagtacg gagaaataaa agtagggaaa agcgccagct tagctgtttt cagcgaggac
     1741 ctctgtactg atgactggca aaaagtgatg gctgcggaag ttatcgctac ctatcttgat
     1801 ggtgacttag tttacaagaa ataatgcttt tcgatataac gttataaaac gaattaaaga
     1861 gaggttaaaa aatggaaaca atgaaaagaa aattcacctt cccacatagt tatacattga
     1921 tttttatctt aattattttg gctgcaattt taacttggat aattcctagt ggtcagtttg
     1981 agacagttgt tgaaaacgtc gcaggtatgg aaaaaacaac ggttgttccg ggaacctatc
     2041 accaaatcga taaggcagat tatggacaag gtttttcctc tatactaatg gcaccagctg
     2101 aagggattat ttcagctgtt gaggttgttg cttttgttct catcgttggt ggtgccttcg
     2161 ggattatcct aaaaacggga gccatcgatc gagggctgtt taccttagca aaagttctgg
     2221 gagacaaggg gatcttagtt attccgatgt cgatgattct attcagctta ggaggatcaa
     2281 cctttggcat gagcgaggaa gtcattccct tatttgcggt gtttatttct ctgatgtttt
     2341 ctcttggcta tgattccatg actgcgatct tgattctatt tttaagtaca caagcgggat
     2401 atgttgggtc gacgattaat cccttcaacg ttttaatcgc acagggagta gctggcgttt
     2461 acggaaatcc cctgctttgg tttcggatgc tatcctggat tgtcattact gggatttcaa
     2521 ttgttttcac catgctttat gctagcagag tcaaaaagaa tccactgtcc tctattgttt
     2581 atgagagtga tttaaaggtt aagcataagt ttcaaaattt tgacactgaa aaagagtttt
     2641 caacacaaga taaactaatt atcgccggtt ttatcgtagg tttaggaatc atgatttggg
     2701 gtatcatttc caagggatgg tatatggttg aaatttctgc actattctta ggattaggtc
     2761 tttttgctgg gggcatcgct agattttctc aaaaggaaat tgctgaagct tttgtcgaag
     2821 gctgttcaga tttcgcctat gctgctgtaa tcattgggct agctagagga gtcttggtaa
     2881 tcttggaagg tggaatgatt attgacacta ttctaaacag cttggctaac cttttaggtg
     2941 gtcttccaaa attcctgttc actacgattc tactcatttc tcaagtaatt gtttcctttt
     3001 ttgttccatc ctcctcagga gctgcggcat taacgatgcc ggttatggca ccattgggtg
     3061 atctaatgaa tgtaagtcgt gatgttgttg ttctaagtaa ccagtttgga aatggtttaa
     3121 tgaatattat ctccccaact agtggtgtat tactggcagg attagccatc gcagagatta
     3181 atttctctaa atggtttaag gttggcttca aaatatttgc catcttaacc cttgtttctg
     3241 ctgttttgtt atacattgct acactctttt agtcttaatc atccattaat aggaggcaat
     3301 agttatgatt aaaataaatc aattagcagg aatgaatatc cactatttat tttattctct
     3361 caaagaattt ttcgcttatc aacagaaaat tggtatttct tctgttgaac tttggggagg
     3421 tgctccgcat tttttcatag atgctttta
//
LOCUS       DAFLWQ010000163         3401 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.168, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000163 DAFLWQ010000000
VERSION     DAFLWQ010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3401
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.168"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            71..871
                     /locus_tag="L1V16_002955"
     CDS             71..871
                     /locus_tag="L1V16_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HBN1277219.1"
                     /translation="METIIQIMKKYDFSEMETRVYTTLLEKGNLTGYEVSKISGVPRS
                     KVYNILEKLLKKNLIVVNKSEPKLYHAISANEFLEKLEKSVKNDLSFLTKNLGMIKEK
                     DEEEMLWKVDGIEYVLDKVEHLVKNAKESLLIQVWHENFTDSLLKALQQAEKRVDKFV
                     LILFSSTHEYDLPLEKYYIHGFETDKLADFGARWINIVADEQEVVFGTINEELQSTDV
                     TWTKNHAMVNLAKEYVKHDAYTLKVIAESPEELKAKYGEGFEGIRKIY"
     gene            887..1765
                     /locus_tag="L1V16_002956"
     CDS             887..1765
                     /locus_tag="L1V16_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBN1277220.1"
                     /translation="MIRNILLTLIVAINLYFIIYFLRDLFKNKQNFKEEPGDMRLLPF
                     TSFIIFFLSTFGVSDFAIGTVLYPKLKWVSMKKLPGTLNTQCVVPVAVMALSYITAIN
                     VGIKTLAVCIICQIIGAYLGPRFVVKLPEKTIKLFVGIGLVIAALLIFAGQMNWIPSN
                     GTASELYGGKLILAGFLLFVYGALNNIGIGSYALTMVTVYLLGLNPVAAFPIMMGACT
                     FSVPIGSVQFIKFNEYSRKITLFTSTFGVLGVLVAVFLVKSLDTYILKWIVILVLLYS
                     AYTMLGSQLKKVTAAN"
     gene            1778..2758
                     /locus_tag="L1V16_002957"
     CDS             1778..2758
                     /locus_tag="L1V16_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBN1277221.1"
                     /translation="MLFLKKEDIIKSFSMREAIDADKKALSLYSAGKASVPLRTNIDV
                     PKSNGQSLYMPAYVEGGEGALGVKIVSVYPENIKKNLPSVPATMIVLDPETGMVSACL
                     DGTYLTQLRTGAVQGAATELLAREDAKIGALIGTGGQAQSQLEAMLTVRKLEEVRIFD
                     IDFERASQFAEKMMQQFSVTMRPTKTSQECVEGADIITSVTTSKRATFSAEWVKKGAH
                     INGVGAYTPEMCEIPREIIKAADVVIFDTMDGVLKEAGDFISPLQDGYIQRDSYHGEL
                     GQLINEELIGRTSGEQITIFKTVGSAVLDVVVATEIVKKAKENNLGKLIF"
BASE COUNT         1172 a          557 c          712 g          960 t
ORIGIN      
        1 tgacagataa tcaaaaagaa tttatagttg ttaccgtagt agctactaaa aataaagtga
       61 ggattaatca atggaaacga ttattcaaat catgaaaaaa tatgattttt cagagatgga
      121 gacaagagtg tataccacac tattagaaaa aggtaatctt acaggatatg aagtaagtaa
      181 aatctcaggt gtgccacgct cgaaagtata taatattttg gaaaaactat taaaaaagaa
      241 tttgattgtc gttaataaat cagaacctaa actttatcat gccatctcgg caaatgagtt
      301 tttagagaaa ttagaaaaaa gtgttaaaaa tgatctttct tttcttacca agaatctagg
      361 gatgatcaaa gaaaaagatg aagaagaaat gctgtggaaa gttgatggta tcgagtatgt
      421 tctggataaa gtagagcatt tggtgaaaaa cgcaaaagaa agtttgctca ttcaagtttg
      481 gcatgagaat ttcacggatt cactactaaa ggcattgcag caagctgaaa aaagagttga
      541 taagtttgta ctgattttat tcagttctac ccatgaatat gatcttccct tagaaaagta
      601 ttatattcat ggttttgaaa cagacaaact tgctgacttt ggagcaagat ggatcaacat
      661 cgtcgccgat gagcaagaag tcgtgtttgg taccattaac gaagaactgc aatcaaccga
      721 tgtcacttgg acaaaaaacc acgccatggt caatctagca aaagaatatg tcaaacatga
      781 tgcatataca ctaaaagtga ttgcagaatc tcctgaagaa cttaaagcaa aatatggtga
      841 gggctttgag ggaatcagaa agatttacta gtaggaggaa ttttttatga ttcggaatat
      901 tttgctgaca ctaattgtcg caatcaatct atattttatt atttactttc taagagacct
      961 tttcaaaaac aaacaaaatt tcaaagaaga accaggggat atgcgtctgt tgcccttcac
     1021 gtcatttatc atcttctttc tttcaacatt tggcgtttcc gactttgcta tcggaaccgt
     1081 cctttatcca aagttgaaat gggtcagcat gaaaaaacta cccggaacgt tgaataccca
     1141 atgtgtagta ccggtagccg tcatggcatt gtcttacatc actgccatca acgtagggat
     1201 caagacacta gctgtttgta ttatctgcca aattatcggt gcatatttag gaccaagatt
     1261 tgtcgtgaag ttaccagaga aaacgatcaa actgtttgtc ggcataggat tggtcattgc
     1321 tgcattgttg atttttgcag gacaaatgaa ctggattcca tcaaacggaa cagccagtga
     1381 attgtatggc ggaaaattaa tcttggcagg atttttactc tttgtctatg gtgcattgaa
     1441 caatatcggc attggttctt atgcgttaac gatggtaact gtctacttgc taggcttgaa
     1501 tccagttgca gcctttccta ttatgatggg ggcttgtacc ttctcagtac cgatcggcag
     1561 tgttcaattc attaaattta atgaatacag cagaaaaatc acacttttta cttcaacctt
     1621 cggtgtattg ggggtattgg tcgctgtatt cctagtcaaa tctttagata cctatatcct
     1681 gaaatggatc gtgattttgg tcttactata cagtgcatat acgatgttgg gcagtcaatt
     1741 aaaaaaagtt acagcagcta attaaggagc gattcaaatg ttatttctta aaaaagaaga
     1801 tattatcaaa agtttttcaa tgagagaagc catcgatgcg gacaaaaaag cactgtcatt
     1861 gtattcagca ggaaaggcaa gtgtgcctct tcgcaccaat atcgatgtgc caaaaagcaa
     1921 cggacaaagc ttatatatgc ctgcttatgt agaaggtggc gaaggcgcgc taggtgtcaa
     1981 aatcgtttcc gtgtatcctg aaaacatcaa gaaaaactta ccaagtgtac cagcaacgat
     2041 gatcgtattg gatccagaaa cgggtatggt atccgcttgt ttggatggta cttatttgac
     2101 acaattaaga acaggcgctg ttcaaggagc agcaacagaa cttcttgcaa gagaagatgc
     2161 taaaattggc gcgctgattg gaaccggcgg acaagcacag tcacaattag aagcaatgtt
     2221 gaccgttcgt aaattagaag aagttcggat ttttgatatt gattttgagc gtgccagcca
     2281 atttgctgaa aaaatgatgc aacaattttc tgtaacgatg cgcccaacaa aaaccagtca
     2341 agaatgcgtt gaaggagcag acatcattac aagtgtgacc acttcaaaac gtgcgacatt
     2401 ctctgctgag tgggtcaaaa aaggtgcgca catcaatgga gtcggtgctt acacaccgga
     2461 aatgtgtgaa attccacgag aaataatcaa agccgcagat gttgttattt ttgataccat
     2521 ggacggtgtt ctaaaagaag ctggggactt catttcaccg ctgcaagatg ggtatattca
     2581 aagagacagc tatcatgggg aactaggcca actgatcaat gaagaattga tcggtcggac
     2641 aagtggagaa caaatcacga tcttcaaaac agttggttcg gctgtattag atgtggtagt
     2701 tgcgacagaa atcgttaaga aagctaaaga aaataatttg ggaaaattga ttttctaatt
     2761 aaaaaggctg aaattaaaac ctttattatt gcgtttaaaa aaagaaaaca aagaagtttg
     2821 taatcaaatg gaaactgacc ccataattta aataaaataa aaaacatctc ttgttgaatt
     2881 ctagtaatga agcgacccta aaacttagac caaaaaatct aacttttggg tggagttgtc
     2941 aagaaaaacc gggcacttag ttaaaaaata agttggacgg gttatactaa aattgacacc
     3001 aaattaagag aaagcgaaga tctggattat gccaagacgt tcatttgatg aaatatttaa
     3061 aattaccgct gtaaaactgg taacggaaga agggttttct gttaaagaag ttagtctata
     3121 gctagaagct cgctctaata gcgtgtattg atgagttcaa gaagttgaaa aatatggata
     3181 acgtactttt ctcggtagag gaagtcatga aatccattcg cagaaatgaa attacacgct
     3241 tagaaaaaga gaataaacgg ttaaaagaat aggtagaact cctaaaaatt accgaagtct
     3301 tcctgaaaga aaaggctctt cgtcaaattg tgttggcgaa gacaaatttg aataaaactt
     3361 agtccgatat gcggcgcgtt ctgtgcgccg catatttttt a
//
LOCUS       DAFLWQ010000164         3347 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.169, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000164 DAFLWQ010000000
VERSION     DAFLWQ010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.169"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(451..1761)
                     /locus_tag="L1V16_002958"
     CDS             complement(451..1761)
                     /locus_tag="L1V16_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBN1277222.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="L1V16_002959"
     CDS             complement(1773..3191)
                     /locus_tag="L1V16_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1277223.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
BASE COUNT         1036 a          677 c          516 g         1118 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataagattga taacttt
//
LOCUS       DAFLWQ010000165         3332 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.170, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000165 DAFLWQ010000000
VERSION     DAFLWQ010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3332
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.170"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(554..2167)
                     /locus_tag="L1V16_002960"
     CDS             complement(554..2167)
                     /locus_tag="L1V16_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBN1277224.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2308..3216)
                     /locus_tag="L1V16_002961"
     CDS             complement(2308..3216)
                     /locus_tag="L1V16_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1277225.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
BASE COUNT         1084 a          565 c          580 g         1103 t
ORIGIN      
        1 tgttaaataa ataggaacaa aaaaattaaa ttatttaata cacacattag ggatcattca
       61 ttgaaggatt agaagacaac gaggatggcg aaaaatatga ttacaataga aaagtcgttc
      121 taaaccaatc agttcctagt atcacacaac gcaagccagt cgatttggtg agattagagg
      181 agtgaaagca aactttatta tataagaaaa aatattcgaa agggatgcta gtttaggtac
      241 tagtgctgat agattaatat gatgcctcgt aatattaggc gtagttactc tagagacatc
      301 actatggact atgatttgtc tcagagtcac aacatgtttt tttatgaaaa gaaacagcta
      361 aaataattaa attgcgcaat gtttaaactt tcttaaacta taacctaata aatgtgaaga
      421 aataatgcac aatttcttca catttatctt ctattctata tacataccaa ccaacaaccc
      481 tatatacttt ttcattttta ctcctcaagt aaaaataact cctagaccgc ggctacccac
      541 cgcggtcgtt tttttattct tcaatcaaaa tcgctttgat acccaaacct gccaagattc
      601 gggcagaagt ataagtattc aatcctcttc tgaaagtaat gtaaactttt ttatcttttg
      661 ggatttcatt gattcgatct cgtaactcat tcattggaat attttttgtt gccgagatac
      721 tgccagaagg tgctttatta ggttcacgta tatctaaaaa gaacgcttct ttcaaatcgt
      781 tttcgggtat atcacttgct ttgatcgttt ctacgatatt cgtcatttga ttgattgcga
      841 cataaccagc tatattcaac gggtcacggg tagtagaata cggtggagag taaggcaact
      901 ccaaatcagg caaatcaaag actgtcaagt ttccggtgat tgctacagaa agttctccca
      961 tccgtttatc gacacctttt tctccaaatg cttgtccacc taaaatacga ccgctatctg
     1021 catcaaaaat cagctttaga tttaatcttg tagcttctgg atagaaatag gcatggtcaa
     1081 agggagtgat aaaaacagtt ttataatttg ttatgcctga tgcttttaat tcatgttctg
     1141 tcattcccgc ataacttgct gtatgatcaa agatttttgc gacacctgca ccaatatatc
     1201 cgcgatagcg cataggcgta ccatttaaaa tatctgccag catatgtcct tgacgattgg
     1261 ccgcactgga aagcatactt tggatcggct gaccagtcac tacactagtc gtttcgataa
     1321 tatcgccaat cgcatagatg tccggcagat tggtttgtaa ctggtcatca acaatgatct
     1381 gacctgtatc tgataattgt atgccggttg ctttcaccac ttcattcttc ggagaaacac
     1441 caacagcaaa aattagcata tcagcagaaa ggacggagcc atctgataat actatttctc
     1501 gacctttatc acggatctca gtaactcttg tttctaaatg aacggctaat ccttctttca
     1561 gcaatttgtc ataaactaaa ttagcaattt ctggatcata agggaaagcg acttgtggca
     1621 attgatcgat taaagtcacg tctaagccgc gatgcttgaa attctcagct aattccagac
     1681 ccataacacc tgcaccaaga atgacgacat gttgtggatt tttttcttca aggaacgatt
     1741 tgattcgatc cgcatccgtc acactacgga ggacaaagcc gttttctgct tcaaaaactc
     1801 cgggaatatc cggataatct ggtctagcac cagaagagat gatcaactta tcgtaatctg
     1861 tttttatttc ttcatttgtg gataggtctt taactgttaa tcgcttagta gaaggatcga
     1921 ttgctgttac ttcgtgttta gtaaagacat cgatgttgtt ttttgttttc aatatttctg
     1981 gtgtacgttc gatcagcgag tcacggtcag tgatcacacc tcctaaataa taaggcaaag
     2041 cacaacttgc ataagaaata ttttctccgc gttcatagat aatgatttcg tgcgcttcat
     2101 tcaatcgacg gaaacgagtg gcaaatgaag gaccgccagc tacaccgcca atgacaacaa
     2161 ctttcataaa aacatctcct tttctacgtt gatcgtacta tgttatggta aaaaacagca
     2221 aataattgtg ccggaaaatt attgtttatt ttgaatagac agaaaatata gagaaataat
     2281 ttgtggataa aacctaaaaa tttttttcta ttttaaggat agataatact ttgaagggga
     2341 taaccctgta tattttttaa aagctgaaga aaaatgatgg atcgaatgaa atcctaatat
     2401 atctgcaatt tctgtatagg ttaattcatt ttctagcacg agacgttttg ctttttccat
     2461 ttttagttct ttaaaatagc taataacact ttttccattc acttttctaa aatgtttttt
     2521 taagctggct ggactgataa aaaaaatttg ggctaattgt tcaagcaaaa aattttctga
     2581 aagatgttct tctaaatatc gtatgattgg atcaactaat tcatctgaat aaagaatatg
     2641 ctttttttta ggaatgactt tctcatttga aggtattgtc aataaagcaa gttcctgttg
     2701 ataatgcctt ggtaaggaag acaattgaat tttttgcaga caataagtaa ctaataagga
     2761 aagcaaatga atgctcatct gttggcatag tatgaaaaaa gaattgattt cctgatcata
     2821 ggaaatagct ggcttactat gttttagata atcaattttg aactgttcat ttttcagaaa
     2881 agtaatgata gatgttattt cttgatctat agaaaaagat tgtcccgtaa tatgtgctaa
     2941 taattgctca tcaaaataaa actggataat gataaaagtt tgtgtttcct tttgagtaga
     3001 aaagatttgg acttcttgct gtttatcaat gaataaaagg gaaggattat ctagttctat
     3061 agatttatgt gcaaattcag catataaatt agcgctttca tttattagta gtcgaaaata
     3121 gggagcagca gataaatgaa gatgggtatc tatggaatag gttagtgttt ttttgacaag
     3181 attggaggat tggttgtttg ttaacaaaag aaccactttc ctttctcttt ttatataaaa
     3241 agctttctat ttataattaa tgactattat aacaaaaatg aaaagccaaa acgacaagta
     3301 aaatattttt ttatataaat atttgtgtta ct
//
LOCUS       DAFLWQ010000166         3284 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.171, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000166 DAFLWQ010000000
VERSION     DAFLWQ010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3284
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.171"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(87..1034)
                     /locus_tag="L1V16_002962"
     CDS             complement(87..1034)
                     /locus_tag="L1V16_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBN1277226.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
     gene            complement(1039..1791)
                     /locus_tag="L1V16_002963"
     CDS             complement(1039..1791)
                     /locus_tag="L1V16_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HBN1277227.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            complement(1792..2700)
                     /locus_tag="L1V16_002964"
     CDS             complement(1792..2700)
                     /locus_tag="L1V16_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HBN1277228.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            complement(2700..>3284)
                     /locus_tag="L1V16_002965"
     CDS             complement(2700..>3284)
                     /locus_tag="L1V16_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1277229.1"
                     /translation="VTHNKKISYQYHVGQYLPDWHPWEDYRNFFVSNKKTNGCREIFA
                     IELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETGIVGTLSVDVVSRVAK
                     RNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHDNNYSHTIIEDAYLEE
                     IKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
BASE COUNT         1078 a          616 c          408 g         1182 t
ORIGIN      
        1 tctatcccag atttgatttt acaaaactca tcagtcctta ttgacaaaga gcctgaattt
       61 accctctaat cttatcttag tatgttttaa ttgatttcag ttttcaaata attagtcatt
      121 ccacttaaaa taccatattt cggttgatag ccaattgact ggatcttagt aatatctgct
      181 agagagtcat ggatatcacc cgaacgctct tctttgtatt caagtgtcaa ttctacaccg
      241 agaatttcat tgattgcatg aatcaattcc aaaagtgtgg ttgctttacc cgttccaaca
      301 ttgaattgtt tccccagtgc agcttcctca ttcgcaacta aaagtaatgc ttggattaca
      361 tcatctatat aaacaaagtc tctagactgg cttccatcac caaataatgt aaatgaagtt
      421 gcttctccta cgatttgttt cttatagcga tctacgagaa tagaaatcac accactgtat
      481 ggagaattcg gattttgatt tggaccatag acattgaaaa aacgaactgc gctaccgggt
      541 acatcatata aatgacaata atctagcaca tattgttctg cagcgaattt atcaaccgca
      601 taaggcgtca atgggcgaat cacggactct tctttttttg gtaaagtcgg ttcatcccca
      661 taaacagccg ctgaagaact aaacacgatc cgttttaaat caggttgata cttgcggatc
      721 aattctaaaa tcattaatac actttcaaaa ttcacacgat gtgtttctac tggtcgggca
      781 actgaatctg ccacactagc aactgctgct aaatgaaaga tataatcaaa tttattagct
      841 ttcatgatct cttccatcaa ggatttctca gcgacatctc cctcaataaa agtgatattt
      901 ttcgtcatat caagattttc tacttttccc attgataagt catcgacgac gattaccaca
      961 tgttcttctc ctaaatgatt ggctaaggta gaaccaatga agccagcccc accggtgata
     1021 agataacagc tcatcctttt acctccgata taaataatta tagatatctt gaagctccga
     1081 agaatcttct aaaaatttag gaaacaaaaa ttctaaccat ttaaaatctt cttcactatc
     1141 aatatctaaa attagataat ctctcatttt tattatccca cattgcccat caaaaatata
     1201 attacttttt tttagaaatt caggtttaaa agaatacatt gaggcattca tttcaaaaac
     1261 ttcaggtgtc tgttgcctag atgtgtatct tgatttatta actatagtaa cttcattttc
     1321 aattcttttt accatattaa aatagggatt acgtcttgca gaaacaactg aaaagtagac
     1381 gtctttatct aaatttttta gatgttcatc tattaattct tcaagattag aaacttcacg
     1441 taaaggtgaa gtcaaatcta aatctataat taaatcaaat atattatctt ctctttctag
     1501 ttgtaagaat gaatcacgta tcacttcaat tttccctaca gtatctgtag ctaattcagg
     1561 tttacgttct acaattttca cagacggatt taacttagtc gtcaattcta ctaactcatt
     1621 actgtccgta ttcaaacaag tcgtgcaatt atgttcagga tgtttttgtt gatagatatc
     1681 tatcattgct aaagcgaaat ggactagggg ctttcctgcc aaatatttca aatttttatt
     1741 tttaaacccc ttagacccag ctctaccaca aatagtaaat aaaatttcca tttatttctc
     1801 ctcagctatt ttcaatactt cgtttgcatg atataaatca ttccagtttt ctttgcctgt
     1861 tactacgttt tcaaagaaat atttcaactc cttctcatac atatcattag cagattcagg
     1921 catttcttta acaatgtttt cttcaaaact tattttatta tttaataagt caacattgat
     1981 acattcatct aaagtaaaca attgaaattt tcttgtagga actcttccaa aataatctaa
     2041 atgaatttct ataattttat catcgtatct caatatatat gttgctaaat cattactgtt
     2101 aatttcaaga ttcgaatatt taccaaactg tttttttact gatttaggga aaccaaatag
     2161 gtttataata taatccaatt catgtataca gtctaattct actcctcccc ccatagattt
     2221 aaaggcagaa taattatttc tataatcagt accttttctc caatcaggaa gataagtaga
     2281 acaaatagct cttacagaat atactttttt actttgaata ctattacgaa caacttccat
     2341 gatattttta tacctcagtg gagcagcaac ataaatattt ttgtaatcat aattatattg
     2401 agtaagatca atactctcag aaaaagcagg tttttctaaa aatatgtaat caactttttc
     2461 aacaattaca tttagtgttt ccagatgctt aaaagtcgga tttgtaataa aagctatatc
     2521 ataatgtgta tccaaatcgt ctctattttg aatatacgtt atttcttcaa actctttttt
     2581 tccactgcta ctataagctg ttatatcaaa attaatagaa ttcttttttc catagcttat
     2641 tagatttttt agatgtctct ttccaattga ccctaaccca aaaaaaatta ctttcatcat
     2701 taatttacct caatgtcgtt aattaagtta ataatatact tatctttttc aaaagtatat
     2761 tggggttcca ttttcttttc caaaagcgtg aaaaattctt taatctcctc taaatatgca
     2821 tcttcaataa tagtatgtga ataattatta tcatgcataa cctcatcgta caattgaata
     2881 tctgtcatac tagaagtttc ttcattccat gaaaatagag aatccgggtt accttcccat
     2941 tctattaaaa tcttttcacc aattatagtt aaatttcttt tagctactct tgaaacaaca
     3001 tctacactta aagttccaac tataccagtt tcatgctcaa taataagagt gaaactgtcc
     3061 gaataatcaa tatcaagatt ggataatttc tgggtcatta cagtaaacga tttaactttc
     3121 ccaaatgtat ctataatcca aggtaattca atagcgaata tttctctaca cccattagtt
     3181 tttttgtttg aaacaaaaaa attgcgataa tcttcccaag gatgccagtc gggtaaatac
     3241 tgtcctacat ggtattgata agaaattttt ttattatgcg tcac
//
LOCUS       DAFLWQ010000167         3180 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.172, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000167 DAFLWQ010000000
VERSION     DAFLWQ010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3180
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.172"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            60..815
                     /gene="fabI"
                     /locus_tag="L1V16_002966"
     CDS             60..815
                     /gene="fabI"
                     /locus_tag="L1V16_002966"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBN1277230.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            complement(925..1938)
                     /locus_tag="L1V16_002967"
     CDS             complement(925..1938)
                     /locus_tag="L1V16_002967"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HBN1277231.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            2103..3023
                     /locus_tag="L1V16_002968"
     CDS             2103..3023
                     /locus_tag="L1V16_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HBN1277232.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
BASE COUNT          934 a          643 c          605 g          998 t
ORIGIN      
        1 tattattctc tattttttta cgactatcaa atttttatca gaaacaaagg agagtcatta
       61 tgtcatttct agaaggaaaa aaaatcgtca ttatgggcgt cgctaacaaa aaaagcattg
      121 cttggggttg tgctgaagca atgttgaaac aaggggcaga aattatctat acttaccaaa
      181 atgaacgaat gaaaaaatca ttagtcaaat tggtcggcga agaagcattc actgtagaat
      241 gtgatgtttc tagcgacgaa agcatcgaaa aagcaatgaa tgccatcggt gaatatgctg
      301 gggagatcca cggccttgtc catgcagttg cttacgccaa caaagaagaa ttgtccggaa
      361 atgtgtctga tatttccaga gacggctatc aattagctca agatatcagc agctactctt
      421 taattgctgt atcaaaatac gcacaaccgt ttcttgcacc aaacagcggg atcgttagca
      481 tgacttatct aggttcagaa cgcgcaatcc cgaattataa catgatgggt attgcgaaag
      541 cttctcttga agctgctatc cgttatttgg cagctgagtt ctcgcctaaa ggaattcggg
      601 tcaatggaat ctcagctggg gcaatcaaaa cattagctgt cacaggtgtt aaagactatc
      661 aaaaactgat ccagttatct gaatctcgta cgcctgatca gcaaggtgtg acgatcgaag
      721 aagtcggtaa tgcttgtgct ttcttaatca gcccactttc cagcggaatc atcggtgata
      781 ttatctacgt tgacaaaggt gtccatcttt cataaacttt tgttgcattc tttaaagtaa
      841 aacatataaa aatcaggaaa aaacttttta aagtctcttc ctgatttttt ctttttacgt
      901 ttttttcaac tcattacttt gaaattattc cacgacttca atccagcctt ctggtgcttc
      961 tatgtctcca aattgaatac ctgtcaattc atcatacaac cgttttgtta ctggtcctac
     1021 ttccgtttca ctataaaata catgaagatt gttattgtga taaatcccac cgattggaga
     1081 aataacagcc gctgtaccac atgcaccagc ttctgcaaat tgatctagat catcaatgaa
     1141 aatatctcct tcaattgctt gcagtcctag tcgttcttca gctaactgca acaaggaata
     1201 tttcgtgata cttggtaaga tagagggcga ttgcggagtg atgaattttc cgtcttttgt
     1261 aattccaaag aaatttgctg cacctacttc ttcgattttc gtatgtgtgg ctggatcaag
     1321 ataaacacaa tctgagtaat ccagttcttt tgcttctgtt cctggaagta aactcgctgc
     1381 gtaatttccg ccgacttttg ctgcaccagt ccccttagga gcagcacgat cgtaatcaga
     1441 tacaataaaa ttcgttggtt ttagtccacc tttgaaatac gctcctactg gcgtacagaa
     1501 gacgacaaat aaatattctg gagctggatg gacaccaatg ttttcaccga ccccaatcag
     1561 taaagggcgc aagtataatg tagcgcctgt tccatagggc ggcacaaaat cttcatttgc
     1621 ttttaccact tgcttgacag catcaacgaa catcttttca gggaccattg gcatcagcaa
     1681 tcgtctagca ctttgattca tccgtcgact attttgttca ggtcgaaaga gattgacctt
     1741 gccgtctttt cgacgataag cttttagacc ttcaaaacat tgctgaccat aatgaagcgc
     1801 tggagagcct tcatgaatcg tcaggtaatt atcttctgtc aattctcctt cttcccattg
     1861 tccgtctttc catttggcaa taaaacgcca aggagttttg atataagaaa aacctagatt
     1921 gttccaatcg atttgcatat acttaccacc ttcgttattt tctccacatt ttatcattat
     1981 ccatattatt tgtcatttta ttttcagctt ttttccttca ttatagttat ttttgctatt
     2041 tccttttttg aaaacttctt ggtacaatac agaaagaatc aaattttaga aaagaggatt
     2101 ttatgttttc attattagca actgccggta cgacagactc ttctggcgag acattgacag
     2161 atcaagctgt cagcaaagta aatgcgtttc agcggttttg ggacgggatt gattgggacg
     2221 ccattttggc tgcctttatc caaaaaagtt tatatctgat ttttttgatc gtcctttttt
     2281 ggattcttca ccgtgtggga aaatatctga ttgataagtc ttttaatcag tattctaaaa
     2341 aagccattct aaacgagagc cgcttaaaga ctttacatag tcttttaaat actatttttc
     2401 attataccct tggtttcttt tttatctatg caattttatc tgctatcggt gtgccgatcg
     2461 gatcactttt ggctggtgcc ggaattgcag gtgtggcaat cggtcttggt gcccaagggt
     2521 tcatgagtga tgttattacc ggatttttta ttatcatgga acaacagatg gatgttgggg
     2581 actacatcaa gctagcaaac ttaacgattg aaggaaccgt cgtatctgtt ggtatccgta
     2641 cccttcagct gaaagcaacg gatggtactg tccatttcat cccgaatcga aacatcacca
     2701 cgatcagcaa tctctctcgt gcaaatatgc aagtactttt agatattcgg attgttcctg
     2761 aagaaggata tgacaaaatc tatgagatca ttgatcgagt aaatcgtaca ttagctgaaa
     2821 aataccaaga agagctccaa actgaacctt ctatctttgg attagtggat cttggaaaca
     2881 gcaattttgc gattcgtacg gtctgctacg cattgaacgg aaaacaatat gccttaaaag
     2941 aagagttctt gagctcctat gtcaaagaat tgacagcttc tggtttcacg attccgaaca
     3001 gtccaattgc tgtcggaaaa taatttggac aaacgatgca acgaatctca ctaaaaagag
     3061 cgtgggacaa aagtaaagaa cacttttgtc ccacgctcta aacacgtata aacggcggaa
     3121 gcagaagcaa ctccttcgga aataagctga aattcacaaa aatttgaaaa gcaattttcg
//
LOCUS       DAFLWQ010000168         3145 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.173, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000168 DAFLWQ010000000
VERSION     DAFLWQ010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3145
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.173"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            97..363
                     /locus_tag="L1V16_002969"
     CDS             97..363
                     /locus_tag="L1V16_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBN1277233.1"
                     /translation="MDSLPVELQALCWNLIDQNVQKQFPLDYLQIFEFSTEKGNQKLV
                     HRQEEPEERKEYLISPKLRLKSVSQKIWAIDSGEYQTMLLPEEY"
     gene            390..689
                     /locus_tag="L1V16_002970"
     CDS             390..689
                     /locus_tag="L1V16_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HBN1277234.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEMGMLPEDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            863..1414
                     /locus_tag="L1V16_002971"
     CDS             863..1414
                     /locus_tag="L1V16_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HBN1277235.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            1560..1853
                     /locus_tag="L1V16_002972"
     CDS             1560..1853
                     /locus_tag="L1V16_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277236.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            1846..2142
                     /locus_tag="L1V16_002973"
     CDS             1846..2142
                     /locus_tag="L1V16_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277237.1"
                     /translation="MAKLIVLGGLIYGGYWLYQYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            2217..>3145
                     /locus_tag="L1V16_002974"
     CDS             2217..>3145
                     /locus_tag="L1V16_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBN1277238.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQ"
BASE COUNT         1172 a          439 c          639 g          895 t
ORIGIN      
        1 caatcttctt taatagaaga ttgggctatt tttatggcaa aggagggaaa agaaatgttt
       61 caaaataaag gataacgtta tgtcacaaag ggagtaatgg acagtttgcc ggtggaatta
      121 caagctttat gttggaatct aatcgatcaa aacgttcaaa agcaatttcc tttagactat
      181 cttcaaattt ttgaattttc tacggaaaaa ggaaatcaaa agttggttca tcgtcaagaa
      241 gaaccggaag aaagaaaaga gtatctgatt tcacctaagc ttcgtttgaa atcagtgtct
      301 caaaaaatat gggccattga ttcgggtgag tatcaaacga tgttattacc agaagaatac
      361 tagtatctaa aagaaaggaa cgaaaggact tgttagaaac ggctatcgaa gtactggaaa
      421 agtgtgcaca gctggtcact gcttctgaag agtggggcta tgaatccgtt acgatggaaa
      481 aagaggaaat tgaaatgggt atgcttcctg aagatgttca tctaccacgt ttagtgatga
      541 cacatcttta tatttattgc gcaccagaag atggaaaaga ctatgtagtt tatttcatta
      601 cagatattac cagccagcga gaatttgttc gtgggttact ggtagaagga cgattggttt
      661 ggagtcagat tggaggaacg gatgaataag atcgattatt tgagaatgat tgcgaaatgt
      721 ttagaagata tccttaccgc gattcatcaa attctgaaga aaaaaggaga aagaatatga
      781 aatattttca actagtattg acacttataa cggcaatggt aattgaagtg cttgaacaaa
      841 aaatagcata ggagaaaaag agatgattga aaaagaatta gtgaccacac aaacagaagt
      901 ttggcgagat cctcatcata cccatcgcta tgttttcaaa cgacaatggg cgatcaaagg
      961 aaaagaagcg gaagataaat tagcagtagt cattactatt cgtccaacag atacagaacc
     1021 atttacgaat gatttgagta tgttattaat cgaaaagaat atccgacaat taggatttac
     1081 tggttttatt gctgtgaatc ttttttcgta cacaaaagcg aaaagtcctc gggtatttct
     1141 tcgaggaaat gatgaacaat ctttggaaat attaacgact gtttttacag aaaagaaaat
     1201 caataccatt atttttgctt gtggttcgat tacagcgacg agtcaagtgg cttatgaaca
     1261 agcaaagact atttacgatc aattgagtgc gaaacaaaag aagatgacca aagtattgat
     1321 aaatgcagaa ggtaagttat cccacccact aagtattcat gttcgtaatg aatggcaatt
     1381 ggcagatagt caattattat ttcaagaaaa ataacatttt attttctcat gttacttata
     1441 agtagtttta catgcttttt gactttaaaa atacatgtga tgatacatgt tatatgaatt
     1501 atcaatgtac ccagtaatat gctattttca ttatgtaaaa aataacaggg ggtgtgtaga
     1561 tggagattga tgaaacttgt ttgagtaact cttataaaag tatgaatgac ttttttgagg
     1621 aaatggaact ggattcagaa ttgctctatc aattttatct tgcttttcga gggcaacaga
     1681 tttcttttcc aatgaaaatg tacgatcgtg agttagttag aaaaagaatc gaaaacatga
     1741 tagaacagga aaaaactgta gatatccgtc aattgacaga agtttatggt ttctctgcaa
     1801 gatggattca aaaagtaatt aaacaaaaag aaaggagacg agtacatggc taagctgatt
     1861 gtattaggtg gtttaattta cggtggatat tggttatatc aatatatgct tgcgcatccg
     1921 aatatagata aaggaaaagt aattaagaca gttggggtaa tcatagttgg actcatagct
     1981 ctaactaaga aaaataatac taatagccca aaaataatga gaacttatcg ctgtagagga
     2041 tgtggaaggg aaatttctac tagttttaat ccatctgaga gtcctcaagg aagagaccgc
     2101 tgccatacgg gctatcgaca ttattgggaa agaatcgatt aaaagattac catttagatc
     2161 aattaattgt ctgatagaat aagtacgtga gggagaaatt gaaaggggga aatataatga
     2221 aaaaatggct gttattacta ataggaatgg gaattttatt cactggttgt acatctgaga
     2281 atacgaggac taaagcgact atagaaactg atacaacaat tgagactaaa aaaagtaaaa
     2341 cgcaatcaac tgaacaaact acaacagaaa tgaagcaatc tgtggaaaca agtgcaagtt
     2401 caatcactga atcttcttct gaagaggtta agaatacttt gtgggatacg aataaagctt
     2461 ccaaattaga aacttttgtc acacaatggg gaaagacatt aggtcaagaa tataaaagct
     2521 acaatcttca gaataatgta agtctgtatg gcactccttt accacaagcc gtgattaatg
     2581 gcgattggaa aatggcaatc aatgaagcac cagttaccgt acaatggtca gaagatggaa
     2641 ctggtcatgc agatttcaat ttagtagcag tttattctga tgtagaaact ggagaatatt
     2701 tagggcagca tgtttacttt ttcggttttc aaaatggaca acctaaagtt tatttaacgc
     2761 aacaaaatca aggtaatgaa aataattatc tgtactttaa cgaaactcaa aatcaacagt
     2821 taaaacaagg tttcagtgat attgtgaatg gacaaactcc tcaaacacca gtagtagaag
     2881 aatctactca acaagcaaca actacaacga cacaatctac aagtagttca ggaatttcaa
     2941 gttgggaagc tgctaaagaa tctgtgctaa ataataaagc tttatggttg tatgattctc
     3001 ctgataaaaa tgtatcaaat actaatttaa ttagcacaaa tgaatatatg aaagatctaa
     3061 tgcaagatga aaatggaagc tactattcaa ttaatattgt aacggatgat gatggaaaca
     3121 cgaccatggc tggtggaaaa caatt
//
LOCUS       DAFLWQ010000169         3133 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.174, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000169 DAFLWQ010000000
VERSION     DAFLWQ010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3133
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.174"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            2..1636
                     /locus_tag="L1V16_002975"
     CDS             2..1636
                     /locus_tag="L1V16_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277239.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
     gene            complement(1903..3072)
                     /locus_tag="L1V16_002976"
     CDS             complement(1903..3072)
                     /locus_tag="L1V16_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBN1277240.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
BASE COUNT         1011 a          457 c          491 g         1174 t
ORIGIN      
        1 catgaggtgg tatatgaatt tgaaaaaaat tttttctgta aaaatattta tagtttatgc
       61 atttgttagt ttattatatt tatttccagc atttaaaaac atggaaatat ttggctttta
      121 tgatacggca tttcacatta atcgtgcgtt aagtttagaa tctattttta gctcccctat
      181 taattttgaa acgtttagat catatggcat gcaagtaaat aatttttacc catggttaac
      241 tctatatcct ttatttttat tgatcaagtt tactaattta gcaataggct ataacctttt
      301 tctttatatt gttacgctca ttactctatt tatatgtcat tatgtaatgt atgaaattac
      361 caaaaaacat gttactagct cctttttcgc tattatatat acaacatctt cttttaggag
      421 tgtagaaata tttcttcgag gggcaatggg ggaattactc gcaatgtcaa tacttcctct
      481 tattttactc gggtttataa agctttacga ctcaaaaaaa gaatcttggg ttatgttggc
      541 gattagcatg actttattaa tttacactca tgttctttct gtagctatga ctatggtaat
      601 gattataatt gctttaatta ttcaatttta tcggaaaaag aaaatagaaa tcttcttaat
      661 tattaaatta ataaaagctg ctatagttac tttacttctt tcactagcgt ttataggtcc
      721 tatgattgag cagacattgt atcaagatct gaatagacct tatgtggata tattacaaaa
      781 aagagcaatt tatctgggta aagagttttt gattggaagt atagattcag aattactatc
      841 atttggtatt ggcttaactt tgcttatttg tttaattata ctaacattta actttaaaaa
      901 attaggaatc ttatctaaaa tcacttatat aatgggtata atatctattc tactttgtac
      961 aaaaatattt ccatggtttg ccttacaaaa tactccttta aatattattc aagctccttg
     1021 gcgttttatg atattttcaa cattgttcat atctttttca gtatctctat ttatttctcc
     1081 acagttggaa aaattttctt atacaaggag aagaaatttt atactattat taatattagc
     1141 tatttcaatt ttaaattatt catcagtagt taacatggtg aaagaaatga attttcaagg
     1201 aacttattct aatgaacaaa tggaaaataa acttgaagaa tttgagaatt ttgattatgt
     1261 acctataggc tataaaaaag atcaattgct tttgaaaaac catcaagtta cagaagatgg
     1321 tcaagttatt tatagtagct tttctccaaa taaagatgaa attacattta cgtttaaatc
     1381 ttcaaaaggc aaaacaatag ttttacctgt attccggtat aaaggattaa cggttactgt
     1441 taattcaaaa aatgctacag tactaaaaca aggaggtcct tttgttacag taaaaagtga
     1501 aagtggaata aataaagtaa caatcaggta ttcatacaca tttttttcta aaatctcatt
     1561 atttatttct ataatcacgc taattgttct tcttttttat tgcataaaat taaaaataag
     1621 aacaagccat gaatgatttg ctagcacata ttttagcaat ctaaagatac tattttagat
     1681 ttaataggcc ctttgtcaaa taatgttggt aaagagaaat cttagaataa tttggacaga
     1741 acagaaagaa gaacacctct ttctgttctg tttatttgga attaaagtct gtagcaaaaa
     1801 ttgattttta gatttgtccc acactctttc ctacgtttag tcgagtactt tttttaagca
     1861 aatgctattc aaagaagtag tatttgctat cttttcatca tatcagctat ttgccaactt
     1921 agtagttcct tccatcaggt catagatttg gtttcttaga tcagcagtag gcagtttgat
     1981 agttttgtca gcttttatat tgctttccat gatgatagca tcctgtgaat ctttgctaaa
     2041 tatagcagat gtatcaaaag agtcgatatt tccttgcgac aggatataat tatctccgct
     2101 atatacccca ccactatatg gatgtccatt cgcattttca cgccataatg agaagagtaa
     2161 gtctttggaa actagttttc cagataaaac ttgtgtaaac agcgtattta aatcatagac
     2221 ggacatactg atattaccag tccctaattc gttatggatc tctgtttcag attctgtcag
     2281 tggtttaaag taatcatcct ctttagacat ttgataggat agtgcatgat tggatgaatt
     2341 tttgacttgg tcataaaatt ttgtatgctg taatcctaaa ggttcgatga tatcatcggt
     2401 caataatttt tcatacggtt gatttgttaa tttgatcaaa attccagtca atatggtaaa
     2461 gttcaatgaa tcataatgag aggtctgata atctgtaaat tttaagtgct gaatcgcaaa
     2521 ttgaacgact tcttcatcag tcatcggtat ggttggagaa gcagttcggt gcaagcctga
     2581 gcgcatatac agcaagtcac ggatagtaat ttgctggctg ccagcaattt gtggatagaa
     2641 ttgagccagc ttagtatcta aagaaaggtg cccacgctcg acttgtttta aaatcaaaag
     2701 agtagtcaat gctttttgaa ccgaaccaat ctgataataa agagaaggat catttggttg
     2761 ttgcgtgagt ttattcgcat agccatagcc tttttccatg atgatgcgat tatttttctt
     2821 tacgtaaatt gagccaatat aatcattttt tcttaatagt tgatcgattt tttcaacgag
     2881 ctgttgttca ttggtagtca gtatcaactt tttttgagct gattgagcat gggcaactat
     2941 ctgagagtgt tcattattgt aaaattgcca tccaagaata gttcctgtag agaacgcact
     3001 aaggctaaac aacacgacaa cgatcattaa aaatgaatat tttctttttt tagcatgttt
     3061 tccttttttc ataatagttt atttagtctc ctttcttttt tacagaaaga ataaagctaa
     3121 aatagcttgt atc
//
LOCUS       DAFLWQ010000170         3040 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.175, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000170 DAFLWQ010000000
VERSION     DAFLWQ010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3040
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.175"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(28..963)
                     /gene="murB"
                     /locus_tag="L1V16_002977"
     CDS             complement(28..963)
                     /gene="murB"
                     /locus_tag="L1V16_002977"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBN1277241.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(1036..1956)
                     /locus_tag="L1V16_002978"
     CDS             complement(1036..1956)
                     /locus_tag="L1V16_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1277242.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2069..2821
                     /gene="xth"
                     /locus_tag="L1V16_002979"
     CDS             2069..2821
                     /gene="xth"
                     /locus_tag="L1V16_002979"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBN1277243.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
BASE COUNT          856 a          612 c          526 g         1046 t
ORIGIN      
        1 tttacttatt ttaagttcca ttacttatta attggctaaa cttctgcttg tttctgatat
       61 tgcttgtttt tctccaatga tccgcacttc tgtttctaaa gacacatcaa atttttcttt
      121 gattacttct tggatgtgcg caatcaattc aatataatct gtcgctgtcg catgatcgat
      181 attgacgatg aatccagcat gtttttcaga gacttgtgca ccgccccatt tcaggccttg
      241 caatcctgct tgttggatca gctgacctgt atagtgtcct actgggcgct taaagacact
      301 tccgcatgaa gggtattcta atggctgttt tgattgacgc aattcggtca actcatccat
      361 tcttgctttg attgcttcat aatcccctgt ttgcaaactg aatcgagctt ccaatacgat
      421 agcacgtaat tcttggactt tactgtgacg ataagaaaat accatttcgt cttttgtcaa
      481 agttttcaat gttccatctt caagcaaaag atccacttca gcaaaaacat ctttgatctc
      541 tccgccatac gcacctgcat tcatataaac cgctccaccg acacttcccg ggatgccgca
      601 agcaaattca aatccagtca atgattctgc caaagctgca taagtcgtat caatcagtga
      661 ggcacctgct tccgcaatga ccatcgttcc tttgacatga atctgtttca tttcagtcag
      721 catgatgact acaccgcgaa tcccgccatc ttgaacgatc agattgcttg catttcctaa
      781 taccatccaa ggtatatcat ggattcggca ataatcgatg atttgcttta cttcttcttg
      841 ttttttcggg aatgcaagga catcagctgg tccacctgtt ttcgtaaacg tatagttcat
      901 caatggttca tcaaacaata tagtaatcgt ggctaagctt tcaactattt cttctttatt
      961 cactgaggat tttcctttct tttctcaaac gtcctcatta ttctatcacg cttaatacaa
     1021 tcttgccagt cttgttcaaa gttgatgacg gtagtgatct ttaagcactt cctcacataa
     1081 ttcatgactt cttacaactt ctttttgttt aagcaattct gtttccgatt tacctaaacg
     1141 gatctgagaa aagaaggcct ctaccattgg ctcaaacccg cgtttgacta gcgtgtttgt
     1201 ccagtcgcca aattctttca ctttttttcc atcagcatct tgaatgacaa gctgggtcag
     1261 atcgtttact tcataagtac catttttact tgttacttga tatttttcta tattagcgcc
     1321 acttgctaaa tccatcgtta aaatagccgt ttgattttgt gtttctaatt gtaaaatggc
     1381 atattccaaa aattcctttg tttctcttat ctggtatttt gttctcaaaa tgggttcatc
     1441 taataaatac acagctgtat caataagatg taaaaacaaa tcataaagga cgaactctgt
     1501 cgtttctttt gccgctattc gatttttttg caggtggatc aaccgcttat ctgggatacg
     1561 tttcaattct tctaccatag gagcaaagcg ccggttgaaa ccgatcatca aaattatttg
     1621 gttcttatca gctaattctt gcaattcacg aacttcattt agatggacac tcagtggttt
     1681 gtcaatataa acatggatac cattttctag acattttttg gctaattcat aatgtacttt
     1741 tgttgctgcg tggatcatac atgcttcgat tttttcttct aaaagctcat cgatcgtttc
     1801 atatagatgt tggaacccgt actctttttg aattctttct tttgtttctt tatttcttgt
     1861 tgcaaaataa aaatcaagtg ttccttgttt tttcgcataa gttggtaaat atgctttttc
     1921 tgcgatattc cctacaccga ttacaccaat cttcatctac tttcctcctg gatcatttag
     1981 ttactttcat cttacaccat tttttactaa aatgaggtac aatagtatcg caaaggtaag
     2041 gaaattaatt cgaaggagtg tgcttttatt gaaatttatc tcttggaacg taaacgggct
     2101 tcgtgccatc gtaaataaaa attttttaga agtttttcat gagttagacg ccgatttttt
     2161 ctgtctgcag gaaacgaaac tccaagcagg acaaattgat ttagatcttc caggttatta
     2221 tcaatattgg aattacgcgg aacgaaaagg ctattccggc acagcgattt ttgctaaaaa
     2281 accagcattg aatgccactt acggaatggg tatcgatatc catgatacag aaggccgtct
     2341 gattactttg gaatattccg atttctttct tgtaacctgt tacacgccaa attctcaaag
     2401 cgaattaaaa cgtttagatt accgattaga atgggaagaa gccttttata attatttgga
     2461 aaatctaaaa aaacaaaaac cagtcatcgt gtgtggggat ctaaatgtcg ctcatcaaaa
     2521 gattgatttg aaaaactgga aaacgaatca aaaaaatgct ggattcactc cagaagaaag
     2581 agcggctctt tctcgactgt tggataacgg gtttatcgat acattccgtt atttttatcc
     2641 aacccaggaa ggtgtctact cttggtggaa ctaccgattc aattcaagga aaaacaatgc
     2701 tggttggcgg atcgattact ttttgacgag caaagattta gagccaggac tagctgatgc
     2761 aaagatccat acggacatta tgggcagtga tcattgtcca gtagaattag atttgaaata
     2821 aagaggttgt gaaaaagtcg tttagtttcg agtattaaga aaaattttgt gaaaatggct
     2881 ttccacattt tgcataaatt tggcataata ccgagaaact ggcttttgaa cactgtttat
     2941 cgagagattg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa caaaaatagt
     3001 tcctcatatt tttcgtttgg ttgggcttat taccgcagat
//
LOCUS       DAFLWQ010000171         3001 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.176, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000171 DAFLWQ010000000
VERSION     DAFLWQ010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.176"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..449)
                     /locus_tag="L1V16_002980"
     CDS             complement(<1..449)
                     /locus_tag="L1V16_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1277244.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYLK"
     gene            793..1200
                     /locus_tag="L1V16_002981"
     CDS             793..1200
                     /locus_tag="L1V16_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277245.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            1214..1615
                     /locus_tag="L1V16_002982"
     CDS             1214..1615
                     /locus_tag="L1V16_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277246.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1617..1988
                     /locus_tag="L1V16_002983"
     CDS             1617..1988
                     /locus_tag="L1V16_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277247.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(2024..2326)
                     /locus_tag="L1V16_002984"
     CDS             complement(2024..2326)
                     /locus_tag="L1V16_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277248.1"
                     /translation="MLMEGKTQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2730..2903)
                     /locus_tag="L1V16_002985"
     CDS             complement(2730..2903)
                     /locus_tag="L1V16_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277249.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILHLNNS"
BASE COUNT         1051 a          448 c          487 g         1015 t
ORIGIN      
        1 ttttttaaat atgcgttctc tgctcttaaa cgaataactt cttcttcaag agactcatct
       61 ttaagttttt taggaatgtt tagcttggaa ttcatactaa tttttctgcc ccttttttgg
      121 ctctcaagtg aagaagcacc gccttcttca tattgctcta tccatttact tagagttcta
      181 tttgaaccga tattaaattt tttagcagtt tcttggatag aaagaccatt tgtttccata
      241 tattctataa catcaagttt aaattttgta gtgtagcttt tgccacctcc aaccaagcct
      301 tcccaaccat gatagttata aatccttacc caatgtctaa ccagtgtacg atttatttga
      361 tatttatgtg caagatattt gtagccgcct tcgttattta aatagtctga aactactttt
      421 ttcttaaaaa caaatgtata tttccgcaaa aaaagcaccc cttttaatta gatttctagt
      481 ctaacttttg gggtgcacat catttttgag gggaagtaca tatagttgtt gatatagttg
      541 ctaatattgt tagctaattt gttagtaaaa ctgtatacga atttagatag taaaaaaaca
      601 gtttgttcct tatatagagg cacttttact actgattaaa tgtcagatat gcttacaaat
      661 atacttataa atatgcttac aaaattagct aatatttccg ttgacaaagc tttgttacta
      721 ttgttaaact aaattgacta gcaaaagtga aacataaatt tattaaataa atgtaaaaat
      781 taggagaaat caatgtctta tagagtacaa ttaataattt cagaagatgt agaaagtcag
      841 caatttggca ctaatgttat taataaagta attaatccag ctctttctat taatgcgcct
      901 ttaattccta ctgctttatc attttctgta acagctgtgg tgtctgagat agaggataca
      961 gaaaagataa aaatagtaga aattgaagtt ttaaacaaga atgaaaaaca aattttttct
     1021 acgggtgaag tatcggtaag cttgcctcct caagttaacg atataaactt taatataaac
     1081 gccagaaatg tcttggttga agaagcagga gagcattatg ctgttgttaa atttaatgga
     1141 actgagattg gaaggcaaat ctttgatatc aaggtcaaca aaccagtgga aaaaaattaa
     1201 ggagacgata cggatgcttg atatagtacc atcaaataca catcggagtg gtagcttaat
     1261 aaattttgct gcgatttttg cttgcgcatc ggtaattcta gcatctccag ttgttgtgga
     1321 tgcaagttct actccgaaaa ctaaaaatga taatcaactt gtaattacta caaaaaatga
     1381 gattaacaca atttcaagta atgatggcaa aatttttgat gtgataaata cggttttaaa
     1441 aagaaaagct gaaatcaata taaaatatga tgaagattta aacttgtatt tctttgttat
     1501 caaaacaaca tctgaattgt tttcctcaga ttacgatgtt ttggatactc tcgataatgt
     1561 attatctgac tataaatata tggggaaatc tgtagtagca actttggggg aataaaatgt
     1621 ttgactttaa tgaatattta tctatttcca aacaaattga atcagatgat aaatataatt
     1681 ctaaagaatc ttatagaaga actgctgttt caagagcata ctacagtgct tttaaaaaat
     1741 ctgatgagta tttgaaagaa aattatgata ttatttataa tggaagtagc ggaaaaggaa
     1801 gccaccaaac cgtttggaat ttgttttcaa cagttaagga attgaatacc ttaggaatac
     1861 ataatagtgg gtatagaatg ttagagaaaa gaaaatgtgc tgactatatt cctaatgaaa
     1921 ccattacgaa aacagatatg gcgctgatga atcgagaagc agaaaaaata ataaacaaac
     1981 tcacctaatg aatttcaagc gagtttgttt gttatttttt tatttaatct ttgtatcttt
     2041 ctggatcaac gaaagtatac tttatatagt cataacgccg atgatcgcta cgtgcgtccg
     2101 gcacgtcagt cacgatatca aacaaaaagt atacaccctt cttcattcta gttttcgcag
     2161 caggaatttt gaaatagttc ttattagaat agtagagatt gattaataag ctatcttcga
     2221 ttgctaaaaa gaaaacttct gaattccata ctttataaaa atctttgata aatctattcg
     2281 aagggtcaaa tttaaaccat aattgtgttt ttccttccat cagcataaaa gttcacctca
     2341 aaaagagtat acgaacgaat gttctttttg tgaaggcgga atttaatata ctgaataata
     2401 gaaaacaagt acttgtgcca aattatgtgc caaaaaaatt cgaattcaac aaaatgtaaa
     2461 caaatagaaa accttctata ttaagatttc ctgcaataac aaacacaaca gaagacgtgt
     2521 aatagttagt caatggatct aatccaacaa tctaacgatt tttttactgg gaagttatcc
     2581 agggagaagt atgctcaaaa tgccttacac ccaaaattta ttcctcaata tttttgaaca
     2641 gtgaatgttt gaagtaactt tttagtcaaa atcagttgat agggatatta gtgatacata
     2701 tttcaataaa atgtgccaaa gaattaaagc tatgaattat tcaggtgaag aatataattg
     2761 ttaataccgt tatagatcaa aacttcagaa ccattctctc ttttgatgcg catcgctaac
     2821 ttggcagccg cgggtttacc tttttctggt gcactctttt cgtttcctaa ttggacagga
     2881 acaatctcat ttaatttata catagaagac ctccagactt cttgatagct caagtatatc
     2941 ttgaggtgca tttgttagta aggtactgtt ctatggggcg cttacgttaa aaatgttttg
     3001 c
//
LOCUS       DAFLWQ010000172         2949 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.177, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000172 DAFLWQ010000000
VERSION     DAFLWQ010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2949
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.177"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..140)
                     /locus_tag="L1V16_002986"
     CDS             complement(<1..140)
                     /locus_tag="L1V16_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HBN1277250.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YK"
     gene            834..1220
                     /locus_tag="L1V16_002987"
     CDS             834..1220
                     /locus_tag="L1V16_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1277251.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFNKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            1318..1509
                     /locus_tag="L1V16_002988"
     CDS             1318..1509
                     /locus_tag="L1V16_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1277252.1"
                     /translation="MNTLKEDFILAKNGNEEAVVAILKRFSALVHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            2023..2355
                     /locus_tag="L1V16_002989"
     CDS             2023..2355
                     /locus_tag="L1V16_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1277253.1"
                     /translation="MKKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            2265..2468
                     /locus_tag="L1V16_002990"
     CDS             2265..2468
                     /locus_tag="L1V16_002990"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBN1277254.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKMLNR"
     gene            2652..2807
                     /locus_tag="L1V16_002991"
     CDS             2652..2807
                     /locus_tag="L1V16_002991"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBN1277255.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLTDHHITHSMSQTGTPVDNAVIE
                     AFHRSIK"
BASE COUNT         1084 a          484 c          452 g          929 t
ORIGIN      
        1 tttttataat cataaaaaaa ataagtagtt ctatctgagc gatactcttt tataatactg
       61 aattcggaat taaaaaccac gataggtaac tttaaacaaa catgaagaga ctttaataag
      121 acttctttat ctgaaaacac ttttgtttct ctctttcctt tctacatcat taaatagtat
      181 tttatacgtt atctaaaata ctattcctct gtcaaaataa gctaacttac ttcattataa
      241 aatatccact tatcgctttc atgtatattc caccgtaaaa agtacatttt atcaccgaga
      301 actcatcatt tttcatcatg atgaatacta tttacatata tctagttcaa agacaataat
      361 tattatgatc cgttattatc taagcactat acagataata ggaatttttc gtttctaaat
      421 actccaattt gggaatccaa taaaaatttt cgttcaaata cgtgtctatt cgaactcttt
      481 tctagttgtt aattatgaag ggggaagaaa taaaaaatac aatctataca cgaataagaa
      541 tattatccaa aaggaggttt tagaaaagat ttattatacg taaaaagctc aagacatttt
      601 cttagccata aggacatgtt tgatatttaa gaagatatat gaattttctt ttctaagtat
      661 aaagataact atccattatc aactaaaaaa acatttttga aaataaacat cagcagtcct
      721 atcaatgcat gtgagcttat agaagttatt cgcagcgcag cataattgca ttagcttctt
      781 ttcgtgtttt ttgcctcttt tccctttaaa tcttaatgga ggaggtgtgc aatatgtcag
      841 ataacgacga acgcgtaaat gcccagttga ttcgattctt tgaaaaggtc attttgaaca
      901 ccgctaatac ttattataaa aaacaagaag aaattcaaaa acatgaacaa cttgatcaac
      961 tcccaccata tttgtttact aaagatacta taaaatttaa acaaccgatt aatgttttaa
     1021 atgtgactct ccttgttgaa gatataaaat tagcaaaaat ccttcctttg ttgaaagaac
     1081 ctgaacaaat ttttcttatc gaaaaattta tctttaataa aactgataaa gaaattggaa
     1141 aggttctggg tattacaaga cagggtgcga caaatttaaa acatcgactt tacaaaaaaa
     1201 ttcaaaaaat gctggtttaa tatctgcata ataactaatt ttgtatgctt ctttgctcgt
     1261 cctcctcctt ccccaaaaaa taaatagatt ataagttcat gggaagaagg taaatttatg
     1321 aatactttaa aagaagattt cattttagca aagaatggaa atgaagaagc agttgtggcc
     1381 attctcaaaa gatttagcgc tttggtccat aagcaatcct ggagaactgg aaaatatgat
     1441 caagattgtt atcaagaatg tatgcttgca atatatctag ctatctcgaa attcgaaatt
     1501 aaagaataac tcaactaagg gagtctgtga cataagtaaa aagatagttt caaatttcga
     1561 acaataaatt tgaagccatc ttctttataa ttataaagta tcgattttac agcgttctat
     1621 aatgattcat agaatctaaa acgaatgatt ttaattatta acgtttttta attcgttttt
     1681 agcttaaaaa taacttttgt cacagtctca ctcctaaaat tactttattt acgtacgaag
     1741 tgggcaggag gtcgaatcca gaactgggcc atggtacttc aacgaggact tctcctctag
     1801 aattgaaaag catgcgattt accttccgta acgacggtag atttattcaa ctatgtgtcc
     1861 aatcaaaatt tgtctgattt caaaaatagt caagagaatt ttggttgtta aaaactctta
     1921 tctatcaact tccacagttt agttgacaaa ccctgatact aagttgggct atgatacact
     1981 tttcttgact atcagttacg ttaccggaag gaatgaactc tattgaaaaa aacatatgat
     2041 cgtaaattta aactaaagat ttcacaggat atccttgaga aaaaagtaac taccaagaaa
     2101 attgctgaag aatacaatat ctctcgtcca acaatttccc gatgggtttc agaatatcgt
     2161 cgatacggga aaaatgcttt tgctggacaa ggaaaaagat tacctgataa agcagatttc
     2221 tacattcttg aacaggaaaa taaacgacta aaagaggaag acgagtgttc tacgaacaca
     2281 aagatcgata cggatctcca gggatcactc aaaaacttta cgatgaagga atcgaaatca
     2341 ataaacgtgt tgtagctgtt cttatgcgtg aaatgaattt atgcacaaga ggatttcatc
     2401 gacgcaaatc ttctcatggt agagaaaaaa caatcaaaga aatggtaaaa aaaatgttga
     2461 atcgataatt tgaacagaac caaattgatg ctgtttgggt gacggatatt acttacattc
     2521 catgtaatga cggtcgcctc tatttgtcca cctatattga cttagcaact cgtattctac
     2581 gttactatat ggtggattca cacatgaaaa aagagattgt cgtccgtcca ttacaaattt
     2641 attaaggaga attgcctacg gtaattcatt ccgatagagg tagccagcat cggtctttta
     2701 tttatcaaga gctgttgacc gaccaccaca tcacacattc aatgagccaa actgggactc
     2761 ctgttgacaa tgcagtaatt gaagcgtttc atcgatcaat caaatgagaa ttaatcgact
     2821 ccaacaaata taaaagtaaa atagagatga aggtgttaat ccaagattat ttagaagact
     2881 actacccaaa caaaagaatc catacaaaat ttatgatgac tccttgacaa tttgaagcga
     2941 agaaaataa
//
LOCUS       DAFLWQ010000173         2940 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.179, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000173 DAFLWQ010000000
VERSION     DAFLWQ010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2940
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.179"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(246..572)
                     /locus_tag="L1V16_002992"
     CDS             complement(246..572)
                     /locus_tag="L1V16_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277256.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            complement(584..784)
                     /locus_tag="L1V16_002993"
     CDS             complement(584..784)
                     /locus_tag="L1V16_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1277257.1"
                     /translation="MITLNDQFIRSLRRHRADLILTKNDAAKLIGINRKTYVKIENGS
                     KESIRASTYQKLVNWLLNDLKI"
     gene            907..1509
                     /locus_tag="L1V16_002994"
     CDS             907..1509
                     /locus_tag="L1V16_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1277258.1"
                     /translation="MEFTIGGVTLNRIKFYIDSSKKTIKQISTETGINYTTLTNYYRG
                     ERNPRNTETWNILADYFHVPVSYLMGLDETNSIEQPNLDRIKTARLEKKDKIVKNIAS
                     LDSDYFTELSNLYFSMTSLLEVKLQEDDSDFLFLKSILEDSFEYTILFAKQKKFINKA
                     LNLNIDERKELESELFGNLTQVQVNNLKREITARLISKLQ"
     gene            1564..2730
                     /locus_tag="L1V16_002995"
     CDS             1564..2730
                     /locus_tag="L1V16_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1277259.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
BASE COUNT         1037 a          493 c          428 g          982 t
ORIGIN      
        1 aaaaatagga tattgatagt ataattctgc atatatatca gaattagaat agccttgctt
       61 ttcaactaag ctttcaactt ctttttcatt cattgtcaca cctgcttctg attttatttg
      121 ctataataga ttcaaataaa gttttctcag aactttatta ttgagtgttc ccccgatctg
      181 caaactgacg ggaacactct ttttaatttt ttctacttca tcaaatttaa aaaacgaggt
      241 gttttttaaa tttgatgact caatatccat tttttgcatt cttcttttga aaacaactcc
      301 attttttcta ataaaataac tggcaatccc attcttttaa atttcaaaaa agttgtatat
      361 gatacattca aatatttagc catctctttt ccttttagaa atggtctttc taatccggta
      421 tcaattcttg cttgatcaat agcctctttt gtcatttcaa aaacataatt tttcaattga
      481 ttcgtttgtt gtttatctaa cattactgta attcctgcat ccattatttt tctcctctca
      541 ttttctattt cttcaatcag ccaactcgcc aagttgtatt tatttagatt ttcaaatcat
      601 taagtaacca atttaccaac ttttgataag tagatgctct aatactttct ttgctcccat
      661 tttcgatttt gacatatgtt ttccgattta tacctatcaa ttttgctgca tcgtttttag
      721 taagtataag atcggctcta tgtcttctta agcttctaat gaattgatca ttaagagtta
      781 tcattcagcg cctcctttca aattattcac tttgtggttt ttatcttaat aagcacattt
      841 taaaccacaa aacgagtaat atcaattaaa atattactca atttgtggtt ttcatgctat
      901 aatagtttgg aatttactat agggggcgtt actttgaata gaataaaatt ttatattgat
      961 tccagtaaaa agaccattaa acaaattagt acagaaactg gtattaacta tacaactctt
     1021 acgaactatt accgtggtga gcgaaatcct agaaatactg aaacatggaa tatccttgct
     1081 gattatttcc atgttcctgt aagttatttg atgggattag acgaaacaaa ttccatagaa
     1141 caacctaatc ttgatagaat aaaaactgct cgtttagaaa aaaaggacaa aatagtcaag
     1201 aatattgcca gtcttgactc agattatttt actgaattat ctaatctata cttttccatg
     1261 acttctttac ttgaagtcaa acttcaagaa gatgactccg actttctttt tttaaaaagt
     1321 attctagagg actcctttga atacacgatt ctatttgcca aacaaaagaa gtttattaat
     1381 aaagctttaa acttaaatat cgatgaaaga aaagagttag aatctgagtt atttggcaac
     1441 ttaacccaag tacaggttaa caatctaaaa agagagataa cagctcgatt aatatcaaaa
     1501 cttcaataaa actaattatt caatcagcca actcgccaag ttatcagatt ggagagatta
     1561 gttatgtcaa tacaaaagta cacaacaaaa agcggtgcac gatatagtgt ccgcttgtat
     1621 gttcgtaaag atgaaaatgg aaagcaagaa tactatgtaa aaaaagggtt taaaactgaa
     1681 aaagaagcca agttacacga agcaagaaaa aaggtcgaga ttgaagatac cggctatcat
     1741 aagccttcta atgacttgtt tataacagtg tatgaagaat ggttgccttc ttataggaat
     1801 cgtgtacaag aaacgacata tcaacgtaca aaagaccttt tccgcttgca tatactacca
     1861 aaattcggga ataagtccat ttctaagatt actcctgttc actgtcagaa tgcagtcaat
     1921 gaatgggctt taaaattcaa gaatatcaaa cagcttaagt cttacagctc tcaaatattt
     1981 gagtatgcca tttttgcaga gctattacac cgaaatccta tggcaaatac aaatctacca
     2041 aagcgggaaa agaaagaaaa tgaaaattac ttttcattag aagaactaaa agctttttgg
     2101 gatattctca ataaagaaga gcctttaaaa catattttaa tcttccagct tttgattact
     2161 actggtatac gtaaaggaga gctagctgct cttcattggt ctgacattta ttttgaagaa
     2221 cagctaatgt atgttagaaa gagctatgca actattcgaa atgaagagaa gaatgcaaga
     2281 agaaaaactg tcaggattca aaaaaataca aaaaatatat cttccgaacg aatattacca
     2341 attgatgcac aaactattga aatgttaaaa atctggaaaa aagaacaagc tcgagagctt
     2401 ttgcagtttg gcataaatac aaatacaaaa aatcaactta tctttaccta tgtaaatgca
     2461 gacggtgaca ttaatcaacc tttgcatgcg gactattcaa ataatatatt gaaacgttta
     2521 gagaagaaat ataaatttaa gcacgttact attcatggat tccggcacac tcacgctact
     2581 cttctactag aaggtggagc aagtatcaaa gaaacacaag atcgattggg tcataaaaat
     2641 gctgaaacta cccttaacac ttattctcat gttactgaaa aagctcaacg aaatgcgtta
     2701 gaaaaattca ttgcttacac tggtttataa tattgtcatt acctttctca ttaccagaac
     2761 gaaaaaaaga caccttctcg caatgagaaa gtgtctgaaa tcgttggtat aacaacgatt
     2821 aacgttttga aaactgtgaa gctttacgtg ctttcttaag acctggtttt ttcttcgtat
     2881 cattgaataa gtttgaaaag ccttgattta taaaggtttt tccgtaaata tattttgtta
//
LOCUS       DAFLWQ010000174         2801 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.180, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000174 DAFLWQ010000000
VERSION     DAFLWQ010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2801
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.180"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            151..1476
                     /locus_tag="L1V16_002996"
     CDS             151..1476
                     /locus_tag="L1V16_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBN1277260.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            1469..1819
                     /locus_tag="L1V16_002997"
     CDS             1469..1819
                     /locus_tag="L1V16_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277261.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            1816..1986
                     /locus_tag="L1V16_002998"
     CDS             1816..1986
                     /locus_tag="L1V16_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277262.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHKYEYYIGY"
BASE COUNT          992 a          442 c          540 g          827 t
ORIGIN      
        1 taataaagtg atacaatgtg ttgattttac aaatcaacag aagaagtagg gaaataactt
       61 acctatgctt ctttttttgt acatttaatc gattcttctt tacaaaaacg aacgtatgtt
      121 tgtataatgt ggaagaatgg agtgttattt atgatggatt attcaaaaga gccagtaaat
      181 gattactttt tgatcgatat gaaaagcttt tacgcaagtg tcgaatgtat agaaaggaat
      241 ttagatccat taacgactga attagtcgtc atgagtcgag cggataatac aggatcaggg
      301 ttgattttag cttcttcacc agctgcaaag aagaagtacg gtatttctaa tgtcagtcga
      361 ccacgagatc taccgcaacc ttttcctaaa acgttacatg tcgttccacc acgcatgaat
      421 ctctatatta agcgaaatat gcaggtaaac aatattttca gaaggtatgt agcagacgaa
      481 gatttattga tttactcgat cgatgaatcg atcttaaaag tgaccagatc aatgaatctt
      541 tttacgactg aaggaacaag aagtcaacgg agaaagaagc tggctcaaat gatccaggag
      601 aatattaaag aagagctagg attgcttgct acagtaggtg tcggagataa tcccttatta
      661 gctaaacttg ctttagacaa tgaagcaaaa cataatgatg gattccttgc tgaatggacg
      721 tatcaaaatg ttcctgataa agtatggaat attcctgaaa tgacagacct ttggggtatt
      781 ggatctcgaa tgaaaaaaag actcaaccaa attggtatca tgagtattaa agacttagct
      841 aattggaatc catacactat taagagccat ttaggtgtga ttggcttaca gctgtatttt
      901 catgcgaacg ggatcgatcg aacagatata gcgatcccac cagaaccgac aaaggaaaaa
      961 tcatatggta attcacaagt gttaccacga gattatacca ggagaaatga aatcgaactg
     1021 gtggtaaaag aaatggcgga acaagtagct attcgtatca ggcaacataa ctgtaaaaca
     1081 ggttgtgtcc atttatacat tggcacgtcg atcttagaaa cgagaccagg tttttcacac
     1141 cagatgaaga tccctataac agataataca aaggaattgc agaattactg tcttttcttg
     1201 tttgataagt attatgaagg acaagaagta aggcacgttg gaataaccta tagcaagctt
     1261 gtgtacactg attcgcttca gctggattta tttagtgatc cacaaaagca aattgacgaa
     1321 gaaaatttag ataaaattat tgacaagatt cggcaaaaat atggttttac gtcgattgta
     1381 catgcttctt ctatgttaga aggcgctcgt agtattacta gaagtacatt ggttggtggc
     1441 catgcaggcg gcgcaggagg gcttaaaaat gattgattat aatgatcgtg gacgtttaaa
     1501 gtgggcaggt ttttatttat ctgatcatac tgaaaaaatt gatgccgaca atgaacaacg
     1561 agccaatcaa aatttggcaa aagaacaaat gacgactgaa gaggttgcgg aagtattgaa
     1621 cgctgcagtc ataaaaaata gatcagtatg tattcaaaaa gaagaacgaa acgctgaagg
     1681 atactatcca gaagatattg ttagcaagat cttaggtagt gatgagctgg ggatctacgt
     1741 tggaaaaaac aaagttcact acgacgaaat acgtcatatc gaattttacc aggataataa
     1801 atggggtcga ttagaatgaa cattatccag caatatgagc taaagtatat aacctttgat
     1861 cagctatcag aagagatttg gggttatggc cagcgtttga taaatgaggt tggtgttgaa
     1921 cgcttctctt tctatgtaga agctgcagca ggataccata aatacgaata ctatattggc
     1981 tattaaagtg caataaaatt atatttcttt tatgttttac attttgtatc aattctgata
     2041 aaattaccta taggtaatta aaaaatataa aaaaactagt tacaacctta ggacgttgta
     2101 actagcttga agcatactag agctaactaa aatagcacta gaaagcaatg ttaaacccgt
     2161 ccaacaaact tgatttaaca ttgagaccag cttattcagc taaatatagt tgaataagct
     2221 tcttttgttt taaaaaaaca aaaggtgtac tacgaataac gcaagtaaaa gaaatactat
     2281 tacaaccagt aggctacaag taagtattac taaacattgc gtagttagaa cctttgctct
     2341 attgtctaaa gccacaaaat tagagatcag ctttatgatg ctaagagcga gctgcatcca
     2401 tgcggacata ggttcttttg acactattaa ttctcctttt taggataagg gaaattgcta
     2461 gtagtttttt cattagcacc atcccccttc atttgattga gtctagtgct gctgtgatag
     2521 tttgctgttt aatatgctta cattcttatt ataacataaa tgaaacaaac acatggttag
     2581 aggtcgtatc aatcaaaata gtgtctcaca aacgatttat tacttactcc tgctgactaa
     2641 cggactgttc ttcagtaact gtaactatat gtttgttaaa accaccatta cctgtagata
     2701 aaaaccaata tatttactat actcactata ttaaatatat ttagtatagt aaaaactaga
     2761 aacaataaaa tttgtgaatg ttgtataccc ccaaacaata c
//
LOCUS       DAFLWQ010000175         2769 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.182, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000175 DAFLWQ010000000
VERSION     DAFLWQ010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.182"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(35..1129)
                     /locus_tag="L1V16_002999"
     CDS             complement(35..1129)
                     /locus_tag="L1V16_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBN1277263.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            1318..2079
                     /locus_tag="L1V16_003000"
     CDS             1318..2079
                     /locus_tag="L1V16_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBN1277264.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(2194..2634)
                     /gene="fabZ"
                     /locus_tag="L1V16_003001"
     CDS             complement(2194..2634)
                     /gene="fabZ"
                     /locus_tag="L1V16_003001"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBN1277265.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
BASE COUNT          872 a          550 c          466 g          881 t
ORIGIN      
        1 tttctagcgg attatttctg caataactaa ttatctattt tttattttca attaatttaa
       61 agcttgacca tggtttcaaa aagtcaagga ggaataattc gtcatcggag attcttccta
      121 caacattgac acgtccgtcg tttttcatat ccttcaaggc gatttgtgtt tctcctttgt
      181 attgaccgta cccttcattg tcaatcagta catccccatg atgcatatct cgcgtattat
      241 gaggcgggaa atctttatct ttgtagtata cacgagtcat cgttgaacga aggatatatt
      301 ctgagcgatc ccctcgataa ctatgaaggt tatcaaacaa gcagattcgt tcgttttctg
      361 taataccttc ttccgtatct actttcaatg ttggataatc cgcgttaaat gcttctgcca
      421 tttctttcaa ttcttcttca cttgcgtacg catttccaat agaaatatca tcaatcaatc
      481 ctgtaaggat taaatgcttc acttgtgtcg caatttcaag atctcggtgg tcttccagcg
      541 tgcacaagcc atcttgcgta ggccaagggc caaactcagc agattgcgaa ttgacgaatg
      601 ccatcgtatt caaattatat tttctgaatt tttctgaaca aaaaacaaag tgttcgtatc
      661 ctaaaccaga gtatcgatga ggataaaaat tatgagaacc taataaatta tccgtgtttg
      721 gcgaataact catgatgttg tcaacgtaat tcgtgcccga actcatattg atctcgattt
      781 tgataccaaa aggattgcgc gtcatttttg cttcttctgc tcctgtgaat ccgatatcta
      841 agcggacccc gtaggcaccc atcttatgga aaaaagataa gtcatcgtaa gaaatctcca
      901 actgttcaaa taacgctgga ttgatatcaa ccattacttc catgcctagg ctattcgcgt
      961 aatcaactac ttctttaaat tctgaaagaa ctttttcttt atcatcattg atctgcagca
     1021 aactggtaaa aacccgttta tacccatact tatgagctaa atccaagtac gctttgtcct
     1081 tttcaaatgt tgaccgttct ggataaatcg agattcctaa ttttcccata ttaccatttc
     1141 ctcctgcatc ttttcgtttt tgtatccact tacattatag caaacacaaa gtaaatggtc
     1201 tacacctttt ctttttcttt taaaataaat gataaattcc aataatttaa gtaggtattt
     1261 tccctctatt ttgttatcat taaagataac aaaatagtaa attggaaagg aacagttatg
     1321 aagaaaaata aagttatttt aagtattagt ttagcagcag cattgctgtt tgctgctggt
     1381 tgttctgcaa acaacacgac ttcttctagt tcgtctacag aaagttcaaa aagtacatct
     1441 actgcggaaa gcacgactgc cagtagcgtc gatttgaacg cattggaatt accacaattg
     1501 acgaaagatg tcgccgaaaa tgaagatctg gtcgaaatgg tgacgaataa aggcacaatc
     1561 aaaatcaaat tatttcccga acacgcacca aaagcggttg aaaactttat gacacatgca
     1621 aaagacggtt actacaacgg actgactttc catcgcgtca tcaaagattt catgatccaa
     1681 ggtggcgatc ctaaaggcga tggcactgga ggggaaagca tttggggaga aggatttgaa
     1741 acagagatca acaaccacct ttataatata agaggtgcgt tatctatggc tcgctcacaa
     1801 gatcctaaca gtaacggcag ccagttcttt atcgttcaaa atacagatga tatgcatgat
     1861 ggtcttttaa aagacgacta tcctcaagca atcatcgacg cttataaaaa cggcggttat
     1921 ccttcactag atggccatta tactgtcttc ggccaagtga ttgaaggaat ggatgtcgtg
     1981 gatgctattg caaatatcga aacagatagt tcagacaaac caaaagaaga agtaaaaatc
     2041 gataaaatca atatactgca agaagcaaaa caaaaataaa aaaataacgt ctgaatcctg
     2101 catagatgac aacgtatgct aggattcagg cgtcttcttt ttacataaaa agcaagtaag
     2161 cttccttttg ttttgctata tcaggtttta tagtcaagca ttttggttga cgatgaacgt
     2221 gaactcgcac tcacagactt ttttatcatc tacatatgct gcagataacg ctgtaccgac
     2281 tgatcccttc attttggtga tttcaaaatg acatttcagc acatctcctg gaacaacttt
     2341 ttgacggaat ttggccttat tgatcccacc gatataagct ctttttccta gaaactcttc
     2401 tgattttagg ataagtatcg aacctgcttg tgccagtgtt tctagaatca acgcacccgg
     2461 catcactgga ttgtcaggaa agtgaccttg gaaaaaatct tcattgattg ttacattttt
     2521 tgtcgcaacg atcttttttc ctggttctaa agtatctaca taatcaatat aacaaatagg
     2581 ataacgatta ggaatcaatt ccattacttc agtagcagat aatacgtaag acataattaa
     2641 actccttctt tcaggcaatt gccattttca ttactttgac tatcaaagta tcatattcct
     2701 aaatatttag caatcttttt ttaatttaag aaaaaatagt ttgacaatca aaacattttg
     2761 actaataat
//
LOCUS       DAFLWQ010000176         2765 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.183, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000176 DAFLWQ010000000
VERSION     DAFLWQ010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.183"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            959..2053
                     /locus_tag="L1V16_003002"
     CDS             959..2053
                     /locus_tag="L1V16_003002"
                     /inference="COORDINATES: protein motif:HMM:NF016145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="HBN1277266.1"
                     /translation="MKKIGILTFHRAENYGAVLQTYALQEYISKMSSNYEVEVIDYRS
                     PFIEKYYKLLSFKAFTNIKSLKRIVYVLLYNGTLKSKRKIFDNFIDKFIRVSLSEYDD
                     KTIRGLDDKYDLFICGSDQIWSPYSAGFDPIYFLDFVKKRNKKNAYAASFGVEIVPEE
                     TIKEYSRRLKNFNVISVREEIGKKIIKNLIEEDVPVSLDPTLLLSKTEWDLIIEKKRK
                     ISEKYLLIYLITETREIIELAKKVAREKKLKLVYINDNIYKTKGIYNYNNCSPSDWLN
                     LFYNADYIVTNSFHGIAFSINFEKEFSVQYLPEPAKVNSRINNILDNYSLKWRINYDG
                     NEKINYSKVNKILVEDRVASQQILKDIMEY"
     gene            2063..>2765
                     /locus_tag="L1V16_003003"
     CDS             2063..>2765
                     /locus_tag="L1V16_003003"
                     /inference="COORDINATES: protein motif:HMM:NF012745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1277267.1"
                     /translation="MKPKVSIIIPAYNAEYTISRALESALKQTYSNKEIIVIDDGSKD
                     RTLAICKEYQLNNHEIFIFSQKNSGVSVARNLGIRKADGEFIQFLDADDAMEPNMTEK
                     LIEVQRNNDSDYVICGLTIIKDNNIVRTPHLKERNINFINFEDYKYIYPLLAAPCNKL
                     FKKELIVLFEKNFSNGEDLLFNTEYLTKIKKISIIEDCLYKVYLDNENSLNKKMSIST
                     VKSLLLINEYEKEIMN"
BASE COUNT         1083 a          281 c          404 g          997 t
ORIGIN      
        1 aaatatacag taaagataat ctttttttta cgttgtattt aatctatttt ctaagtacgc
       61 aatatatgct ttggaatatt gatatatctc agctaataat gattatctat actccaatga
      121 tgtttatagc tttttctagg tttcatatcg acagatactt ttatgagaaa tttaccttta
      181 gttatatttt gcttatgact tttacttact tttatactcg tttttttctt aatataaata
      241 atggtttagt gataaattct tgttattatt tgttattaac tgttcctata gtttatttgt
      301 ttgttaatcc ttatagaaaa aatattagct ttttattaat tagtatcata attttatttt
      361 caatgaaaag aacagcattg ataacattag cactaattat ttttattgag ttaattttaa
      421 atgttttgaa taaaaaaaga attagtttaa gaagattagc atttcttata ccgtttagcc
      481 tttttattgc agcattgcta attaaaataa acaaaataat atctagtttg tatgataata
      541 atatatttat gcgattttat tctggagata caataggcga atctagaggt gacattttaa
      601 aattattatt agaaaaaata tgtacgaact caaatatata ttttatttta ttaggacaag
      661 ggatcaactc aactatatat tatacaggtg gtttaacagc ccataacgac tttctggagg
      721 ttttatttga ttttggcatt tttggtctat tattatatat tatgatttat ataattttca
      781 taaaaaaaat aaggattatt acaaacgtaa aagacaagcg atcattgtta tatactatgg
      841 tcatcttaat gctagtttcc gtaagtagtc atctaatatt tattcctagt tatgtaagtt
      901 tattaataat gaattataat tatctgaaaa ataaaaatta cttttcaaag gagaactaat
      961 gaagaaaatt ggtattttaa catttcatag agctgaaaat tatggagctg tattgcagac
     1021 atatgcttta caggaatata ttagtaaaat gagtagtaat tacgaagtag aggtaattga
     1081 ttataggtca ccatttatag aaaaatacta taaattacta agttttaaag catttactaa
     1141 tattaaaagt cttaaaagaa tagtatacgt tttattatat aatggtacgt taaaatcaaa
     1201 aagaaaaatt tttgataatt ttattgataa atttattcgt gttagcttat cagagtatga
     1261 tgataaaaca ataagaggct tggatgataa atatgatctt tttatctgtg gaagtgatca
     1321 aatttggagt ccatactcgg ctggtttcga tcccatatat tttttagatt ttgtaaaaaa
     1381 aaggaataaa aaaaatgctt atgctgctag ttttggagta gaaattgtcc cggaagaaac
     1441 tataaaagag tatagtcgac gtttaaaaaa ctttaatgta atatcagtcc gtgaagagat
     1501 tggaaaaaaa attattaaaa acttgattga agaagatgta cctgtatcac ttgatccaac
     1561 actattactt agtaaaactg agtgggattt aatcattgag aaaaaaagaa aaatttcaga
     1621 gaaatattta ttgatatact taattacaga aacaagagaa attattgagt tagcaaaaaa
     1681 agtagcaaga gagaaaaaat taaagttagt atatataaac gataatatct acaaaacaaa
     1741 gggaatatat aattataata attgttcacc tagtgattgg ctcaatttat tttataatgc
     1801 agattatatt gtaacaaatt catttcatgg aattgctttt tctataaatt ttgaaaaaga
     1861 attttctgta cagtatttac ctgaaccagc gaaggttaat tccagaatca ataatatttt
     1921 agataattat agtttgaaat ggagaattaa ctatgatggt aatgagaaaa ttaattatag
     1981 taaagtaaac aaaatacttg tagaagatag agttgcctcc caacaaatac taaaagatat
     2041 tatggaatat tgaggtggta ttatgaagcc aaaagtatct ataattattc ctgcatataa
     2101 tgctgagtat actatttcga gagctctcga aagtgcactt aaacaaactt attctaataa
     2161 agaaataata gtcattgatg atgggtctaa agatagaaca ttagcaatct gtaaagagta
     2221 tcaattaaat aatcatgaaa tatttatatt ctcacaaaaa aattcaggtg tatcagtagc
     2281 tagaaatttg ggaataagaa aagctgatgg agaatttata caatttttag atgctgacga
     2341 tgctatggaa cctaatatga ctgagaaact tattgaagtt cagcgcaata atgattctga
     2401 ctatgtaatt tgtgggttaa ctattataaa agataataat atagtgagaa ccccacatct
     2461 aaaggaaaga aatatcaatt ttattaattt tgaagattat aaatatatct atcctttgct
     2521 tgctgcacca tgcaataaac tttttaaaaa ggagcttatt gtactatttg aaaaaaattt
     2581 tagcaatgga gaagacttgt tgttcaatac ggaatattta acaaaaataa aaaaaatttc
     2641 aatcattgaa gactgtttat ataaggtata cttagataat gaaaattctt taaacaaaaa
     2701 aatgagtata tctactgtaa aatcgttatt attaatcaat gaatatgaaa aagaaataat
     2761 gaata
//
LOCUS       DAFLWQ010000177         2746 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.184, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000177 DAFLWQ010000000
VERSION     DAFLWQ010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2746
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.184"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(205..570)
                     /locus_tag="L1V16_003004"
     CDS             complement(205..570)
                     /locus_tag="L1V16_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277268.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            778..1260
                     /locus_tag="L1V16_003005"
     CDS             778..1260
                     /locus_tag="L1V16_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277269.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1457..2347
                     /locus_tag="L1V16_003006"
     CDS             1457..2347
                     /locus_tag="L1V16_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HBN1277270.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            complement(2634..>2746)
                     /locus_tag="L1V16_003007"
     CDS             complement(2634..>2746)
                     /locus_tag="L1V16_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1277271.1"
                     /translation="GLNNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT          935 a          450 c          540 g          821 t
ORIGIN      
        1 aatattatag atgtttccac ctcaaattca atatctatta ttggaatcat tattgctgca
       61 attattacac aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa atagaaaaac
      121 tagtgatagt tttggtgata taagaaaaac atatatgtat aaaaagaaga aagtagcttc
      181 tctttgtaca tatatggttt gtttttatgg atgccgagct tttttataag ataaggctac
      241 cgcccataac gacccaagga tttgtggaac taagtaaata cctgcaagaa gcaagatcag
      301 ctgggtcggt tttaaaggat gatagaagta acgccattca gtaaaattgg cgcaaaataa
      361 ataggaagtg acagtagata taatattggc aatgaataaa gatataatac gcctgttcct
      421 ttgaaaataa tatccagcaa aaagagataa aaatatcaat gtgatgaacc cgcttacgga
      481 atgataacga aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag ataaaagcaa
      541 cggaaggttt ttccagcaag tttttatcat ctttcatcac cacctaacaa gtgttattat
      601 tttgttagtt ttattgtaaa ttgaatcctg caataatcaa ttactttttc attatttcta
      661 gattaaatga ataaactctc atgccattat ctctaaaaaa aaagtttttc cccctaattt
      721 ttttagatag aaaattgtat agtatgatga gagaaaaagt agtttggggg aacgttaatg
      781 agaagaaaag cagtaatcga tcggctttat ttattttttt ggttttttcc tatcgttttg
      841 ctacctttta catgggtaaa tgctgttgta caaggtgcgg agatattagg cctgatccaa
      901 ggaagcggat ttgtggtttc taggaatttt ccagctttga ttgttttcta tttagtgata
      961 agtgtaggtc tcttattacc aaaatctctg atcaatcact acaattggca gctgctttac
     1021 ttttcttgct tattagtatt tacatctatg ttttctttgc tgcctcgctt gattatcggc
     1081 cctaatggtt tgagcgagag tggattgaag gatttagctt attcctccat gtatttcttg
     1141 acgatcaaac catggttcta tttagtaatt gcctcattta ttcttgcaac atttttttac
     1201 ttctggacag aaatcaggat aaaaagtgaa cgatctgtat ctataaaaaa taactattga
     1261 tggtggatca tcagtaaaaa aacatatgag ctgcgtaaaa tgcatgtttc tcatatgctt
     1321 tttttattat tatgtaaaga atgcgaaaaa cgtttacatg atttttacat aacttaacta
     1381 tatttttaca gcaaccatac gagggattta cagtcgactg ataaacttta gttgtaaata
     1441 agaaaggagc aataaaatga aaaaagtatt gtttactcta ggtatgatgg gaattctttt
     1501 agccggatgc ggctcaggat caggaaatac agatggctct gccacacaaa ataattcaag
     1561 tgactcaaat gaacaagtaa aaatcgttgc ggtaggttcg acagcattac agccgttagt
     1621 cgatgcagca caagaaagct ttgtacaaga aaatccaaat tatcaaatct ctgtacaagg
     1681 aggaggaagc ggaactggtt tgagccaagt cgaagctgga gcagttacta tcggaaactc
     1741 tgatgtattt gcagaagaaa gagacggagt tgatgcttca aaattagtgg atcataaagt
     1801 agcagtggtc gggatggcac caatcgtcaa taaagataca gatgtcaaag atatcaccaa
     1861 acaggaattg attgatatct ttacaggaaa aatcactaac tggaaggaag ttggcgggaa
     1921 agatcaaaaa atcaacgtcg tgaaccgtgc aaacggcagc ggtacccgcg cgacattcga
     1981 aaaatgggga ctggatggtg ctacccctgt gcagtcccaa gaacaagatt catcaggaac
     2041 agttcggcag ctggtaagtc aaacaccagg agcaatcagc tatttagctt tctcatatct
     2101 cgatgattcc acacaagcac taagtatcga cggtgtagaa ccaaaagaag agaatgtagc
     2161 agataacagc tggggaatct ggtcatatga acatatgtac acgaacggaa aaccttcccc
     2221 tgaagtccaa aaattcttag actacatgat gacagaagaa atccaagaag gacctgtcaa
     2281 agaattgggc tatttaccaa tcacaatgat ggaagtagaa cgtgatcacg aaggaaatat
     2341 caaataacta gcagataaac atgccacggt agtcgttact attaaggaaa aatcaactat
     2401 gtttccccac atatacattt ttcctttaat tgtgaaaaat agttcctcat attttgccgt
     2461 tttttgagct aataccgagg gtcagctgat tgaacaccgt ttattcgaaa aaaagagcta
     2521 cgacatagaa ctgtcgtaac tttttttggc tcttcgtcaa atcgtgttgg tgaagacaaa
     2581 tttgaataaa acttagtccg atatgcggcg cgttctgtgc gccgcatatt tttttagttt
     2641 tcaaagatca gaccttgttg taaatagatc cgtgcccgaa agttataaaa gttgcgataa
     2701 ccaaacgcaa ttcgtttaat cagcttgatc ttgttattca gcccct
//
LOCUS       DAFLWQ010000178         2696 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.185, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000178 DAFLWQ010000000
VERSION     DAFLWQ010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.185"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            133..1140
                     /locus_tag="L1V16_003008"
     CDS             133..1140
                     /locus_tag="L1V16_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1277272.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            1152..2156
                     /gene="neuB"
                     /locus_tag="L1V16_003009"
     CDS             1152..2156
                     /gene="neuB"
                     /locus_tag="L1V16_003009"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HBN1277273.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            2153..>2696
                     /gene="neuC"
                     /locus_tag="L1V16_003010"
     CDS             2153..>2696
                     /gene="neuC"
                     /locus_tag="L1V16_003010"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HBN1277274.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILN"
BASE COUNT          984 a          343 c          530 g          839 t
ORIGIN      
        1 cttcatattt taatcaatca aatgttgatt cgttacgttt tgacatcatt attgataatt
       61 agtttagtta tatatttttt aaagattaag aatcgaatta tagatgacta taattcatag
      121 gaggagatat aagtgtttaa aggaaaaaca atattagtaa ctggcggaac tggttccatt
      181 ggaagtgaaa ttgttcgtca gcttttaaaa tatgaaccaa aagctatcag aatttatagt
      241 agaggtgaag aaaaacaatt ttatatgcaa caagagctct caaatcacac taatttgaga
      301 tttttaattg gtgatatcag agactctcaa aggattgatt atgcatgtcg tgatgtggat
      361 attatttttc atgctgccgc aatgaaacac gttccagcaa gtgaatataa tcctatggaa
      421 gctgtaaaaa caaatgtgat gggaactcaa aatgtaatag atgcagcgat caaaaataat
      481 gtaaaacatt ttgtaggtat cagtacagat aaagtagtga gtcctactaa caccatgggt
      541 gcgacaaagt tattgagtga aaaattaata atagctgcca atcagtataa aggaaaaaca
      601 gaaacaatat tttcttgtgt aaggtttgga aatgtcatgg ggtcaagtgg atctgttatt
      661 cctcttttta gtaaacaaat aaaaaacaat aaagatatta ctttgacaga tgttgatatg
      721 acacgattta tgatgtcaat accggatgct gcaagattag ttctgtctgc tgctatgaat
      781 tcaaaatttg gagaaacata tgtcttaaaa atgccggcaa tcaatatttt aactttagct
      841 caatcattaa taaaaatata taatgataca catgatgaaa aatatagagg tgaaataaaa
      901 gttgtaggta tcaggccagg agaaaaatta tatgaagagc taatgactac agacgaaatt
      961 gaacgctcat atgaaaatga taaaatgtat atcattccac cacactatca tgctactgac
     1021 gaactgtaca aagattatga aaaaattaaa atcactgcat actcttcaga tgcaacagaa
     1081 ttaatgagtg gacaggaatt tattagaatc gcaaaagaga ataatgtcgt gacttggtaa
     1141 ggagttttat gatgaaatca gaagtatatg taattgcaga aattggtgta aaccataatg
     1201 gaagtctaga tttagcttta gaaagtattg ataaagctaa agaatgtgga gctaacgcgg
     1261 ttaaatttca aacatttaaa acgaataagc tagtttccaa aaaggctcca atggcaaaat
     1321 atcagaagga taatcttaaa gaggacagtt ctcaatttga aatgctaaaa aaattagaat
     1381 tatctcaatc tgattttatt agaataaaag attattgtat acaaaataaa attgattttt
     1441 tgtctactcc ttttgatgaa gaaagtgcag actttctaaa acaaattggt gtacaaggat
     1501 ttaaaattgg ctcaggagat ttaacaaatt taccttttct tagaaaaata gatatgtatg
     1561 ggttgccagt tttattatct acaggtatgg ctgatattca tgaggtcagt gaggctgtag
     1621 attgtttcat agatagtcca gttactattt tacattgtac ttcaaattat ccggctagtt
     1681 ctgaagatat taatttattg gcgattaaca cattaaaaga aatgttcggg atacccgttg
     1741 ggtactccga tcattcattg ggatatgatg ttggtatttg tgctgttgcg atgggtgcta
     1801 aggtaattga gaaacatttt accttggata aggaactacc tggtccagat cataaagctt
     1861 ctttagatcc tcaggaattt gcagattttg taaagcatat tagaaacact gaaatatttt
     1921 taggtgatgg tgttaagcga gcaatgcctt ctgaacttag tacaaaagaa gtatcaagaa
     1981 aaagcctagt ggtcactgag aatttaaatg tgggagatat tcttacagag aaatctctta
     2041 caataaaacg tcctggaaat ggaatagctc ctaagttttt atatcaatat attggcaaaa
     2101 aagttaaaag accaataagt gcagatagtg ttctgcttga ggaagatgtt gaatgaaaaa
     2161 aatacttata gtaagtggaa cacgagctga ttatggaata tataaacctg ttgctgagaa
     2221 tttactacaa gataattggg atgtatcatt tgttgtttct ggaatgcatt tatcccataa
     2281 atatggattt actaaagaat tgatcttagc tgacggattt agaattagtg gagaagttca
     2341 aagtttgttt ttagagaaca ataagggaaa catggctcgg tctgtggcat tagagataaa
     2401 tggtttcaca aatatatttg aacaaactag ccctgatttt gtattattac taggggatag
     2461 aggagaaatg ttggcagctg cgatagcttg tttgtatctt ggaatcaaaa cagcacatat
     2521 tcacggaggc gaagtgtctg gtactgtaga tgaatcaata agacatgcca taacgaaaat
     2581 agcatctgtt cattttgctg ctacggaaaa aagcaaagag cgtttaataa aaatggggga
     2641 agattcttgg agagtttttc ccgtcggagc tcctagaata gatactattt taaata
//
LOCUS       DAFLWQ010000179         2643 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.186, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000179 DAFLWQ010000000
VERSION     DAFLWQ010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.186"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..546
                     /locus_tag="L1V16_003011"
     CDS             <1..546
                     /locus_tag="L1V16_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HBN1277275.1"
                     /translation="KYVLQVFHPVVTELENIEKQILALINSMEQQSQPIICILPNSDA
                     GSEIIRKMYQKYLKTDIIYITNLEPEEYLTILKECKFMIGNSSSGIIEAASFKIPVIN
                     LGTRQNGREQSKNIINANLNENEIETALNKIQDPQFIKSLKNVKNIYGDGNSSRRITK
                     TLNQILNDGEDIKWIQKQIAY"
     gene            519..1196
                     /locus_tag="L1V16_003012"
     CDS             519..1196
                     /locus_tag="L1V16_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBN1277276.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            1186..2328
                     /locus_tag="L1V16_003013"
     CDS             1186..2328
                     /locus_tag="L1V16_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBN1277277.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            2341..>2643
                     /locus_tag="L1V16_003014"
     CDS             2341..>2643
                     /locus_tag="L1V16_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1277278.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDE"
BASE COUNT          986 a          344 c          513 g          800 t
ORIGIN      
        1 aaatacgttt tgcaagtatt tcatccagtt gtaaccgaac tagaaaatat agaaaaacaa
       61 attttagctt tgatcaattc aatggaacaa caatctcaac caattatttg cattttacct
      121 aatagtgatg ctggtagcga aattatcaga aaaatgtacc agaaatattt aaaaacggat
      181 attatttata ttacgaattt agagccggag gaatacctga ctatattaaa agagtgcaaa
      241 tttatgatcg gaaattcttc ttctgggata attgaagctg catcattcaa aataccagta
      301 ataaatttag gaaccagaca aaatggacga gaacaatcta aaaatattat aaatgcaaat
      361 ctaaatgaaa atgaaattga aactgctttg aataaaatac aagatcctca gtttataaaa
      421 agcttgaaaa atgttaagaa catctacggt gacggcaaca gttctagaag aataacaaaa
      481 acattgaatc aaatattgaa tgatggggaa gatattaagt ggattcaaaa acaaatagct
      541 tattaaaata tactagtgat ccatacatta ttattggggc tggcggacac gcaaaagtca
      601 ttattgaaac cttaagatta gaaaataagt taatatatgg attttttgat gataagcaaa
      661 ataaaatgca agatctgaaa tatcttggga aaataaacga attgaatagc tgggcggata
      721 gcaaaaaaaa aatctataaa tttattgtag ctattggtga ctgtgtagta agaaaaaaga
      781 ttataaaaaa attgaatatg ccaagtgagc aatatggaat agctgttcat ccaagtgcta
      841 tagtggcaaa agaaatttca attggttatg gaactgttat ttttgcgaat gctgtaatta
      901 acccagatgc tgtaattgga gagcatgcta taataaacac aggtagcatt gttgagcatg
      961 attgtagaat taataactat gttcatttat ctccaggtgt atgcttagcg ggtggagtac
     1021 atgtaggtgt aggaactcaa ataggaattg gttctcaatg tatccagatg aagaaaattg
     1081 gatcttggtg tatgataggc gcagggagca ctattgttaa ggatattccc tcacattcct
     1141 tagcttatgg caatccagct aaaattaaga aagaaggaat taattttgaa ttctagaatt
     1201 ttattatcaa gtcctcatat gggaggaaca gaagaaaaat atgttgctaa ggcttttaaa
     1261 gataattgga tagcgccatt aggtgaaaat gtggataaat ttgaagaaag tattacaaaa
     1321 tatactggtt ctaagggcgg agcttctgcg ttaagttcag gtacagctgc catacatctt
     1381 gccttaagac tgcttaatgt tggaaaaaac gatattgtct ttgctccttc atttactttt
     1441 atagctacag taaatcctat tttatatcaa ggggctgtac cagtgttcat tgactcagaa
     1501 cctaatacat ggaatatgag ccctgttgca ctagagagcg cattagaaga agctgaaaga
     1561 aacaaccaat tacctaaggc aatcatcgta gtgaatttat atggtcaaat ggctgattat
     1621 gaacgaattt tagctattgc aaaccaattt aatgttccag tgatagaaga tgcagcggaa
     1681 tcgttaggtt ctacttataa gggaatttcg tcaggcttat ttgggacaat tgggatctat
     1741 tcatttaacg gtaataagat catcacaacc tcaggtggag gagctctagt gtctagtgat
     1801 aaaaaatatg ttgagcattc aagattttta gcaacacaag caagagatca agcaccgtat
     1861 tatcaacata gcgaaatagg ttataattac cgtctaagca atatttctgc cggtatcgga
     1921 cgtggacaaa tggaagtatt gaatgataga gtagctaaac gaagagaaat tttcaatcga
     1981 tataaggaag ctttttctgg aattgataga attgaaatga tgccagaagt ggatggcatg
     2041 gtgccaaatc gttggttgtc tactttaacg atcaatgatt ataattctat tgatcaagta
     2101 gttaacgtaa taaataaact aaatgaaaaa aacattgaaa caagagcttt gtggaaacca
     2161 ctacatttgc aaccagtatt tcaaggggta aaaatgtatt accatgataa taatcttagt
     2221 gtgtcagaaa agttatttaa tagcggctta tgcttacctt ctggaagtaa tatgacagat
     2281 agtgaacaag aatttgttat tgatgagttt aaaaaaatat tcaagtaggt gtgatatttt
     2341 atgaacatag gaattattgg tttaggttcc atggggaaaa gaagacttag actcattcaa
     2401 gaacacttta atgatatttt actatgtggt gttgatacta atgaggcgag acgaaaggaa
     2461 gttgaaaagg aatttggaat accaacttat aatagtctaa cagaggcaaa aaatttgttt
     2521 gaaataaatt cagtttttgt ttgtacatcc cctataaccc atgaatttat tataaaagag
     2581 gctttaaatt tagattgtaa tatctttacg gaaatcaatt tattaaatga atattatgat
     2641 gaa
//
LOCUS       DAFLWQ010000180         2620 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.187, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000180 DAFLWQ010000000
VERSION     DAFLWQ010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2620
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.187"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(1..317)
                     /locus_tag="L1V16_003015"
                     /pseudo
     CDS             complement(1..317)
                     /locus_tag="L1V16_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
     gene            complement(391..672)
                     /locus_tag="L1V16_003016"
                     /pseudo
     CDS             complement(391..672)
                     /locus_tag="L1V16_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
     gene            1134..2516
                     /locus_tag="L1V16_003017"
                     /pseudo
     CDS             1134..2516
                     /locus_tag="L1V16_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          940 a          456 c          433 g          791 t
ORIGIN      
        1 tttcgtaacc agatatctaa ggttaagccg tccgcatcaa ttgcacgata aagataatgc
       61 caacgtccct taattttgat ataggtttcg tccattttcc atgaatagaa ggattgtcta
      121 tttttcttct tccaaagata atagaggact ttgctgtact cttgtaccca acgataaatc
      181 gtagtatgac aaacatttat tccacgatca tatcacaatt cctgaacttc acgatagctt
      241 agattgtaac gcaggtagta accaacagcg acaataatga cgtctttttt gaattgtttg
      301 cctttaaaat gattcattac tctgtcctct ctgtcttttt tctcaatttt acactaaaat
      361 agattttttg gaaaactttg caacagaacc gaaatgagta tagtatgaat tagtaatttg
      421 gttttcatct aagtttagct ttgatttact aaaattgata tctcgataca tgttcaatac
      481 atctaataca aatcgagaat cttctttcgg aaatggctca gaaagatcac tccaaatttc
      541 atcatcataa tgatactcgt aaccttctct caatatttcg atttttcttt cataataaga
      601 tctgttttgg tcctcaaatt tagccaataa ctcaaattga tttactagtg acaatctctg
      661 aaaactgtcc attaaatgtt tcttcctatc ttgttcatta acaaaaaatt ataagccctt
      721 acaacgaata ttatatatta aatttaattg taggtgaaca cgaattttat aaatatttat
      781 ggtgttaatg acaaatgata tccgactcct cttcatacgt tctggactat ttgctaatag
      841 attaaaattt cagcatctat ttctgaccat aaataaatga gctgccgaaa agctgccaaa
      901 tcagacttga aaataaagga tcaaaaactt ttaagtttct gaccccgtaa ctcacacttc
      961 aaaatcttac ttaaaaagga gtctgaaaga aaaaaagagt attcaaaatt tttttctaac
     1021 tagctacatc acatctatgc attgacactc aaagaaccag aataagtcat cagaaagcaa
     1081 gggggtgcgg acataatcct ggacgaaaaa ataaacttag gaggaatgtc cgtgtgtttt
     1141 cccacaaaga gcgtgtaagg gcaattcagt tatttttaaa atacgattgc tcttatgctg
     1201 caaccattcg agaattaggg tatccgtcga ttggtgcact acggaaatgg tataaagagt
     1261 atttggaatc cggagagctc catcaggagc accgaaaaaa atcaaagtat tctgaagaac
     1321 aaaaacgaat agcggtgaat cattattttg aatatggtca atgttatgca cgaaccattc
     1381 gcatgcttgg ttatcctaat agagagtcct tgcggcagcg gtgtgaagaa cttgcaccag
     1441 gagctagaaa actccgaaaa agtgcggtaa agttaacaca agatcaaaaa gaagctgtgt
     1501 tgaaaaaatt ctataaaccg caaactaata ggaaaaattt agccgaatct ggaggaatta
     1561 gtagagttac tctatatcaa tggaaaaaca cggttcttgg aaaggatttt ccattgtgta
     1621 tgactttaaa aaatcaggaa aaacaaaaag agctactttt aaaggaagta gaagacttac
     1681 aaaaacaagt acaccaatta cagctcgaaa aagcattact cgaaggagcg gctgaactgc
     1741 taaaaaaaga aaaaggcgtc aatcttcttt gtctatcaaa tcaagaaaaa acgatattga
     1801 ttgatgcctt acgaaatcag ttcaccttga aagagcttct tcaacagctc cagtttccta
     1861 aaagcagcta tttttatcaa aaacaagcac ttgagaaacc agataagtat tacaaagaac
     1921 gtcaaattaa ttatcacgat tttcaatcat aacttctgtg cgtatggtta ccgtagaatt
     1981 caccaagctt taaaaaatat gggtaaaaag ctttctgaaa aagttgtacg tagattgatg
     2041 actgaggaaa atctatttgt taaattttct agacgaaaaa agtattcttc gtatgctggg
     2101 gaaatttctc ctgcacaccc caatttatta aatcggaatt ttaaagcaaa gaagccaaat
     2161 gaaaaatggt taacagatat tactgaattt agaattctcg cagggaaaat ctacttatca
     2221 ccacttgtcg attgttacga tggtgctatt gttagttgga ctattggaac aaagccaact
     2281 tgcttcactc tatgtctaaa aagagttatt caccagataa ttcagcgtgc gaaggtttct
     2341 ttggacgatt aaaaaacgag atgttttatc aacgtgactg gaagaataca acaatcaatc
     2401 agtttataaa caaattggat gattatattc attggtataa taatcaacga attaagttat
     2461 ctttaggaag gctaagccct cttcaatatc ggaagaagca aagatatatt tgttaaaaag
     2521 gtccaaaaaa aatatccgca cccccttttt tttgtaaaaa actattgcac aatacaagta
     2581 gcctacggct atcgaaattt ccataacttt cgagcaagaa
//
LOCUS       DAFLWQ010000181         2527 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.188, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000181 DAFLWQ010000000
VERSION     DAFLWQ010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.188"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            1003..2007
                     /locus_tag="L1V16_003018"
     CDS             1003..2007
                     /locus_tag="L1V16_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1277279.1"
                     /translation="MLGDSLVVLAGLSGTGKSQLVTSYAKALQLSDTQIKFISVRPFW
                     EDDSDLLGYADTVNSVYRPGDSGLIDALLEASRHKENIYMVCFDEMNLARVEHYFSQF
                     LSVLEMEPNTRKIKLYNEDLENKLYNSSTYPSTIEVGQNILFVGTINTDESTHQFSDK
                     VLDRSNIISLELVPFHEISEVNDYIQSDQKKRNQLKYDDFKNFKNSNPTNGLTQKEKE
                     MFWKLHLAINSKDKNIGIGWRILKQIDEYLKNLPVQNDLSRKEAIDIQLVQRVLSKIR
                     GSDEQLSELVGKWNENDLKQVGEFEQIINEYPESSDFKYTKKILLQKARELNLHGFTL
                     "
     gene            1991..>2527
                     /locus_tag="L1V16_003019"
     CDS             1991..>2527
                     /locus_tag="L1V16_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277280.1"
                     /translation="MDLPFSLKLNFGYKSEEQEYELLFFQDEASLLEYTPVKVKEFSN
                     LSFTFNSIDKHAKLYIPELDDYLIENQVKEENGDICYIPSDDNIIIYNRDQGKTVPLI
                     PGYYTLYVKIGETIFYSRFEIILKDLGTPEWEKMKIEIEKMVGGLARTFIPKKTSRRE
                     ITTSNYLMNDQLFQRILEF"
BASE COUNT          994 a          333 c          397 g          803 t
ORIGIN      
        1 aggaaaatat aaatggtttt aaaacaaggt aaacaagatt accaaattat tggttatttg
       61 gaggatgatt taaataaaat taaaataaac tcggatgatg taatgtactt ttttatgact
      121 cctctttcag atttccccag tagtgtgatt gataatgtag agggtataca aatatatagt
      181 aatacgctta ctaaatttgg gtttattgat gatataaacg aatctcatag tactcgtgcc
      241 caatcactta aagaattttt agatccttat attatcgttt gtacaccaaa aattaaaaga
      301 aatcatgaac aagcaagaaa ttactatcaa ggtgatgatt tagaattaat ccccaaacca
      361 aagtctgaag tttttaaaaa tttaataaaa gagaatgaat cattagtacc tataccggtc
      421 ttttctataa ataacagcga ttctgtaatc aaagacgaga caagttttga aaaccaatta
      481 ctaaacggca aactactcgg aaaaattata aatttctcaa aagacaatga agattaccct
      541 ttaaatgttt tttgggagaa cactgatgga tcaagagttt tatttggtga aataatcgga
      601 caaaacaatt caatgtacgg tgtagcatat aggatagaaa aagataattt ttacaaaaag
      661 tttattgatg aaggtagtaa aaactatgta ggttacgatg attttataaa tcaaacaaaa
      721 gatataattt ttgtgcccta tctattactt caaaaaatta tagaaactaa aaaagatatt
      781 aacgaaggca tagaaaatat ctctgattcc aaaatatctc cagtaagttc aattattact
      841 gaacaaacgc aaatagatat atctgagtta gaagataaac acgctattca acaaaatgat
      901 cacttctctg aacataatga atttatagaa agatttaatc agctcacaat tcgtagtaaa
      961 ttacattact caaaacgaga cttatggaat tttcatactg ctatgttggg tgatagtttg
     1021 gtggtattag ctggactaag tggtaccggt aaatcacaat tagtaacatc ctatgcaaaa
     1081 gcacttcaat tatcagatac acaaataaag tttatttctg tgagaccctt ttgggaggat
     1141 gattctgatt tattgggcta tgctgatact gtaaattctg tctatcgtcc aggagatagc
     1201 ggtctaattg atgcactatt agaagcatca agacataaag aaaatattta tatggtttgt
     1261 tttgatgaga tgaatttagc tcgggttgaa cattatttct cccaatttct ttcagtttta
     1321 gaaatggagc caaatactag gaaaatcaaa ctgtataacg aagatctaga aaataaatta
     1381 tataactctt caacctatcc ttctacaatt gaagtaggac aaaacatatt atttgtagga
     1441 acaataaata cagatgaatc tactcatcaa ttctcagata aagttttgga tagatcaaac
     1501 attatttcac ttgagttagt accattccat gaaattagtg aagtaaatga ctatattcaa
     1561 tcagatcaaa agaaacgtaa tcaacttaaa tatgatgatt tcaaaaattt taaaaactct
     1621 aaccctacta atggtttgac ccagaaagaa aaagaaatgt tttggaaact ccatttagca
     1681 attaattcta aagacaaaaa tatcggtatc ggttggagaa tattaaaaca aattgatgaa
     1741 tatttaaaaa atcttccagt gcaaaatgac ttatcaagaa aagaagctat tgatattcag
     1801 cttgtacaga gagtattaag taaaatcaga ggttctgatg aacaattatc agaattagtt
     1861 ggtaaatgga atgagaatga tttaaaacaa gtgggtgaat ttgaacaaat aattaatgaa
     1921 tatcctgagt cttcagattt taaatatact aaaaaaattc ttttgcaaaa agctagggag
     1981 ttgaatttac atggatttac cctttagtct gaaattaaac tttggttata aaagtgaaga
     2041 acaagaatat gaacttttat tttttcaaga tgaggcatcg ttattagagt atacaccggt
     2101 taaggtaaaa gaattttcta atctaagctt tacatttaac agtatagaca aacacgcaaa
     2161 actatatata ccagaattag atgattattt gattgaaaat caagtaaaag aggaaaatgg
     2221 agatatttgc tatattccaa gtgatgataa tataatcatt tataataggg atcaaggtaa
     2281 aacagtacct cttattccag gttattacac tctttacgtt aaaataggtg aaactatctt
     2341 ttattctcga tttgaaataa tacttaaaga tttaggtaca ccagaatggg aaaaaatgaa
     2401 aatcgaaatt gaaaaaatgg ttggcggtct tgctagaact tttattccta aaaaaacttc
     2461 tcgtcgtgaa attactactt caaattatct aatgaacgat caactttttc aacgaatatt
     2521 agagttt
//
LOCUS       DAFLWQ010000182         2493 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.189, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000182 DAFLWQ010000000
VERSION     DAFLWQ010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.189"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..828
                     /gene="glyQ"
                     /locus_tag="L1V16_003020"
     CDS             <1..828
                     /gene="glyQ"
                     /locus_tag="L1V16_003020"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBN1277281.1"
                     /translation="TEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNR
                     LYQHHQFQVVMKPSPENIQELYLESLRLLGIDPLEHDIRFVEDNWENPSMGCAGVGWE
                     VWLDGMEITQFTYFQQVGGLPCKPVTSEITYGLERLASYIQEVESVYDLEWADGVKYG
                     EIFKQPEYEHSKYSFEVSDQDLLLSNFDRFEKEAKRCIDENLVHPAYDYILKCSHTFN
                     LLDARGAVSVTERAGYLSRIRNMARAVAKIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            830..>2493
                     /locus_tag="L1V16_003021"
     CDS             830..>2493
                     /locus_tag="L1V16_003021"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBN1277282.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVL"
BASE COUNT          836 a          465 c          540 g          652 t
ORIGIN      
        1 acagaaaaag gagcaggtac gatgagccca tatacattct tacgggcaat cggaccggaa
       61 ccatggaatg ctgcttatgt agagccatcc cgccgaccag ctgacgggcg ttatggagaa
      121 aacccaaacc gtttgtatca gcatcatcaa tttcaagtcg taatgaaacc ttcacctgaa
      181 aatatccaag agctttattt agaaagcttg cgccttttag gaattgatcc attagaacac
      241 gatattcgtt ttgttgaaga caactgggag aacccatcga tgggttgtgc cggtgtgggc
      301 tgggaagtat ggcttgatgg gatggagatc acacaattca cgtacttcca gcaagtcgga
      361 ggactacctt gtaaaccagt tacttctgag atcacttatg gattagaacg tcttgcttct
      421 tatatccaag aagttgaaag tgtctatgat ttagaatggg ctgatggcgt gaaatatggc
      481 gagatcttca aacaaccaga atatgaacat tccaaatatt cttttgaagt aagcgaccaa
      541 gacttactac taagcaattt tgaccgtttt gaaaaagaag ctaaacgctg tatcgatgaa
      601 aatcttgttc atccagcgta tgattatatt ttgaaatgca gccatacatt caatttatta
      661 gatgctcgcg gtgcagtatc tgtaacagaa cgagcaggtt atctttcccg tatccgcaac
      721 atggctcgtg ctgtagccaa aatctttgtg gcagaacgcg aaaaattagg attcccttta
      781 ttgaataaaa acacagcaaa tccagaaaac gtgaaggagg ctgaataaga tggcaaaaga
      841 cttattactt gaaatcgggc tggaagaaat gcctgctcat gtagtcacac caagcatgaa
      901 acaattagaa gaaaaaacag caaaattttt agatgaaaac caattgactt atgatacgat
      961 cgaaacattt tccacaccgc gccgtttagc aatcaaagta acaaatattc cagaacgaca
     1021 agcggacagc gaagaagaag tcaaaggacc agccaaaaaa attgctttgg acgcagatgg
     1081 aaactggacg aaagcagctg aaggatttgt ccgcggacaa ggtctgacga cagatgctat
     1141 cacttttaga gaattaaaag gcgtggaata tgtctatgta acgaaataca ctcacggcaa
     1201 agaagcaaaa gaagtattga caggtttagc agatgtcatt aaaagcctca ctttcccagt
     1261 aacgatgcat tgggcagaat acgattttga atatatccgc cctattcact ggatcgtggc
     1321 attgttagat gacgaaataa tcccgtttga gatcttggat gtcaaaacag acagagcttc
     1381 aagaggtcat cgtttcttag gcgaagatgt aacatttgcg catgcaaaag aatacgaaga
     1441 aaaattaaat gaacaatttg ttattgcttc accgcaaaaa agacaagaaa tgatcgttac
     1501 acaagcaaac gaattagcag aaaaaaatca ctggatcatt gatctagatg aagatttact
     1561 agaagaagtc aacaatctag tcgaatatcc aactgtcttt tctggagact tcgaggaaaa
     1621 atatctttct gttcctgaag aagtactagt cacttctatg aaagaacatc aacgttattt
     1681 cgaagtacgg aacgatcaag gtatgttgct tcctcatttt atttctgctc gtaatggcga
     1741 tcgggtaaaa ttggaaaatg tggtacgagg caatcaaaaa gtattgactg ctcgtttaga
     1801 agatgcggaa ttcttttata atgaagacaa gaaagcttca atcgaccaat acgttgaaaa
     1861 attaaaaact gttactttcc atgaaaaaat cggtagcatc tatgagaaaa tgcaacgggt
     1921 acaagtcatc gctcgcatca taggcgaaca agtaggacta tctgaggaag aattgatgga
     1981 tctgcaacgc gctgctgaaa tctataaatt tgatctagta accaacatgg taggagaatt
     2041 ccctgaacta caagggatta tgggagaaaa atatgctctg cttaaaggcg agaaaccagc
     2101 cgtagcaaca gcaatccgtg aacattacat gcctatatcc agtgaaggag atctacctga
     2161 gactacagta ggttctgttt tagcgattgc tgataaatta gatagtatct tttctttctt
     2221 tgcagttggg atgatcccaa gtggctcaaa cgatccatat gctttgcgcc gtcaagcata
     2281 tggtgtcgtt cgaatcatcg aatcgaaaaa atgggccttt cctttgtctg ttctgcaaga
     2341 aacgattagt gaagttatca gtaaagatac ggatcgtttt ggcattggct tgtcagcggg
     2401 acaacaacag gtgatcgact ttatcaaagg ccgtctgcgc caattattga caacgaagaa
     2461 tatccgtcat gatgttatcg aagctgtttt gaa
//
LOCUS       DAFLWQ010000183         2493 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.190, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000183 DAFLWQ010000000
VERSION     DAFLWQ010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.190"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..828
                     /gene="glyQ"
                     /locus_tag="L1V16_003022"
     CDS             <1..828
                     /gene="glyQ"
                     /locus_tag="L1V16_003022"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBN1277283.1"
                     /translation="TEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNR
                     LYQHHQFQVVMKPSPENIQELYLESLRLLGIDPLEHDIRFVEDNWENPSMGCAGVGWE
                     VWLDGMEITQFTYFQQVGGLPCKPVTSEITYGLERLASYIQEVESVYDLEWADGVKYG
                     EIFKQPEYEHSKYSFEVSDQDLLLSNFDRFEKEAKRCIDENLVHPAYDYILKCSHTFN
                     LLDARGAVSVTERAGYLSRIRNMARAVAKIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            830..>2493
                     /locus_tag="L1V16_003023"
     CDS             830..>2493
                     /locus_tag="L1V16_003023"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBN1277284.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVL"
BASE COUNT          819 a          464 c          553 g          657 t
ORIGIN      
        1 acagaaaaag gagcaggtac gatgagccca tatacattct tacgggcaat cggaccggaa
       61 ccatggaatg ctgcttatgt agagccatcc cgccgaccag ctgacgggcg ttatggagaa
      121 aacccaaacc gtttgtatca gcatcatcaa tttcaagtcg taatgaaacc ttcacctgaa
      181 aatatccaag agctttattt agaaagcttg cgtcttttag gaattgatcc attagaacac
      241 gatattcgtt ttgttgaaga caactgggag aacccatcga tggggtgtgc cggtgtgggt
      301 tgggaagtat ggcttgatgg gatggagatc acacaattca cgtacttcca gcaagtcgga
      361 ggactacctt gtaaaccagt tacttctgag atcacttatg gactagaacg tcttgcttca
      421 tatattcaag aagttgaaag tgtctatgat ctggaatggg ctgatggtgt gaaatatggc
      481 gagatcttca aacaaccaga atatgaacat tccaaatatt cttttgaagt aagtgaccaa
      541 gacttgctac taagcaactt tgaccgtttt gaaaaagaag ctaaacgctg tatcgatgaa
      601 aatcttgttc atccagcgta tgattatatt ttgaaatgca gccatacatt caatttatta
      661 gatgctcgcg gtgcagtatc cgtaacagaa cgagcaggtt atctttcccg tatccgcaac
      721 atggctcgtg ctgtagccaa aatctttgtg gcagaacgcg aaaaattagg attcccttta
      781 ttgaataaaa acacagcaaa tccagaaaac atgaaggagg ctgaataaga tggcaaaaga
      841 cttattactt gaaatcgggc tggaagaaat gcctgctcat gttgtcacac caagcatgaa
      901 acaattagaa gaaaaaacag caaaattttt agatgaaaac caattgactt atgatacgat
      961 cgaaacgttt tctacaccgc gccgcttagc aatcaaagta acaaacattc cagaacgtca
     1021 agcagacagt gaagaagaag tcaaaggacc agccaaaaaa attgctttgg acgcagatgg
     1081 aaactggacg aaagcagctg aaggatttgt ccgcggacaa ggtctgacga cagatgctat
     1141 cacttttaga gaattaaaag gcgtggaata tgtctatgta acgaaataca ctcacggcaa
     1201 agaagcgaaa gaagtattga caggtttagc agatgtcatt aaaagcctca ctttcccagt
     1261 aacgatgcat tgggcagaat acgattttga atatatccgc cctattcact ggatcgtggc
     1321 attgttagat gacgaagtaa tcccgtttga gatcttagat gtcaaaacag gcagagcctc
     1381 tcgaggacat cgtttcttag gcgaagatgt gacatttgcg catgcaaaag aatatgaaga
     1441 aaaattgaat gaacaattcg ttattgcttc accgcaaaaa agacaagaaa tgatcgttac
     1501 acaagcaaat gaattagccg aaaaaaatca ctgggttatt gatctagacg aagatttact
     1561 agaagaagtc aacaatttag tcgaatatcc aactgtcttt tctggcgact tcgaagaaaa
     1621 atatctttct gttcctgaag aagtactagt cacttctatg aaagaacatc aacgttattt
     1681 cgaggtacgg aacgatcaag gtatgctgct tcctcatttt atttctgctc gtaatggtga
     1741 tcgggtaaaa ttggaaaatg tggttcgagg caatcaaaaa gtattgacgg ctcgtttaga
     1801 agatgcggaa ttcttttata atgaagacaa gaaagcttca atcgaccaat acgttgaaaa
     1861 actaaaaact gttactttcc atgaaaaaat cggtagtatc tatgagaaaa tgcagcgggt
     1921 acaagtcatt gcccgtatca ttggcgaaca agtaggacta tctgaggaag aattgatgga
     1981 tctgcaacga gctgctgaaa tctataaatt tgatctagta accaacatgg taggggaatt
     2041 tcctgaacta caagggatca tgggcgaaaa atatgctctg ctgaaaggcg agaaacctgc
     2101 tgtagcaaca gcgattcgtg agcattacat gcctatatcc agtgaaggag agctacctca
     2161 gtctacagta ggttctgttt tagcgattgc agataaatta gatagcattt tttctttctt
     2221 tgcagttggg atgattccaa gcgggtcaaa cgatccttat gccttacgtc gccaagcata
     2281 cggtgtcgtt cggatcatcg aatcgaaaaa atgggccttt cctttgtctg ttctgcaaga
     2341 aacgattagt gatgttatca gtaaagatac ggatcgtttc ggcattggtt tatcagaagg
     2401 gcaacaacag gtgatcgact ttatcaaagg ccgtctgcgc caattattga caacgaagaa
     2461 tattcgtcat gatgtcatcg aagctgtttt gaa
//
LOCUS       DAFLWQ010000184         2444 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.191, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000184 DAFLWQ010000000
VERSION     DAFLWQ010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.191"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..630
                     /locus_tag="L1V16_003024"
     CDS             <1..630
                     /locus_tag="L1V16_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBN1277285.1"
                     /translation="KNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTA
                     FKIFRAIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLN
                     FKIGMFAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDP
                     SMNKWFDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            623..2050
                     /locus_tag="L1V16_003025"
     CDS             623..2050
                     /locus_tag="L1V16_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBN1277286.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            2052..>2444
                     /locus_tag="L1V16_003026"
     CDS             2052..>2444
                     /locus_tag="L1V16_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277287.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKS"
BASE COUNT          853 a          285 c          394 g          912 t
ORIGIN      
        1 aagaatagtt cagtggagtt tattcgtgga atagatctag atcaaattaa acataaagaa
       61 ttttattata aacatataga tgtatatcaa aaacatgatt atcctagaat taataggaat
      121 aacacaactg catttaaaat ttttagagct ataattaatc gttgtctgag gatgattaaa
      181 cttcccccaa aaattagaca ccataaattt gatttgtatc atggttctca atggtgggct
      241 ttgtcgaaag aatgcctaac agaattaata caaatgtatg aacaaaatca acaagactac
      301 ctgaatttta aaataggtat gtttgcccca gatgaaaaat tttttcatac actttttttt
      361 aattcctcgt tcaaaaataa aaatgttatt ggaggaccag atttaccact tgaattgaaa
      421 aatattgaag aaactacttt acaaacttcg aaattagcaa atattcatat tattgatcct
      481 tccatgaaca aatggtttga tgaaagggat atagatcaaa taaaagaaag tgaaaaatta
      541 tttgtaagaa aagttaaatc ggattactct gataaactat taaatagaat tgataaagaa
      601 attttgaaag ttggaaatat agatgaatag aatagtacct gttttagaga agagtttatt
      661 aagtcgagat gcgtttcgag taataaattt aatcatttgt ctgctttatt ttatgcctag
      721 tacttttaat gtaactaata tcccgatgaa aatagctttt gcttggggtg gaattatagt
      781 tttgtatgag gtttttataa agaaaaattt ttttaaaatg cgtttttctt ggctactgat
      841 tggagcaatg attagtttta tcttaactat aatcattaac agagaaaatt ttttaattcc
      901 atctatttat aattttggat atttgctgat tactttgata gtaatttttc ctgcagactt
      961 ttcacaaagt gaagaggaaa aaaagaaaaa aatggtgtat tttaataatg ttttcattat
     1021 cataattttt ttagctgcgc taatatctat ctatcaattt atttttttga tttcttatca
     1081 tgtcccaaca ggaacgccag gattacttgc aagacaaggt tttattgaac atcggttatt
     1141 tggtgtctat acaagtccaa atgttggagc tatgtttgga tatacttcta ttattttaag
     1201 tttaattagt gtattaattt caaaaataac aaaaacgatt cgtgtttttt atatgatgaa
     1261 ttttatcgta caaatatttt atattacact ttcttcgtct agaggtgccc aggtagtaat
     1321 ttgttctttt ttagtattat ttcttttgtt gtttgccaat tcaaaattta gaaagagcat
     1381 tagagaagta ctacctgtaa aaatcaaatg gatggtaagc atattattag ttctattggt
     1441 atatttttct tttggtacta attatgctaa ggatttttta gcaacaattc ctgtatcgat
     1501 tgatagaaaa gtagaagtta tagagtcaaa tgaatcagat aaaactccac ttccagaaaa
     1561 agaagtaata ttacagcatt ctagtgataa ctccgaaatt tcagctggtc gttttacgat
     1621 ttggaaagct gcgcttaaag ttataagacc aactttgtta tttggttatg gagagaccga
     1681 tttctatggg aatagcgatg caaaattttt gaaaaaagta gatcttgata ctacagatgt
     1741 gaatgaacta aaaagagcac atggaaacat gcataatgga tttcttcaag tacttgtatc
     1801 aagtggtata attgctttta tatgtatcta tgctttctat gtgttaaata tctttagttt
     1861 actcaaaaca ttttttagaa gtaaagtgaa ttatgcgttt cttggtattg ttttaatttt
     1921 tatactatct atttttatag atgaaatggt ggaggctcat gtacttttca ataagcgcga
     1981 tgtcatttca attgttttct ggtattattt gggaagcatt tcttacttgt atttaaaaaa
     2041 ggagaattaa tatgaagaca gctttcattg cttggactcc tttacatttg attaatatat
     2101 taaatgttta tcaaaatttt taccgagaat caaaaggaga tttatttatt tattctgaat
     2161 ttgaaaacgc tagaagatat agtgagcgta taaaagaatt agggctattt aatgatgttg
     2221 tttttgtgaa tcaccggaaa atcggttctt cctttaaacg taaaattaac ttgttaacta
     2281 accataatca atttttctcg gatgatttat ccgtttatga tgaaattttt atacaggggg
     2341 aaaattattt cacaaaaata cttttctcca atgtttacaa aaaaaatcca gatgtaaaac
     2401 taaattatat agaagatggt ttgggtactt atttgaagaa gagt
//
LOCUS       DAFLWQ010000185         2441 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.192, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000185 DAFLWQ010000000
VERSION     DAFLWQ010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2441
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.192"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..404
                     /locus_tag="L1V16_003027"
     CDS             <1..404
                     /locus_tag="L1V16_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1277288.1"
                     /translation="EEIKNYAKKSGIDDDIKFLGNRNDIEKFYQAFDVLMLPSLFEGV
                     PLVGIEAQFADLPCFFSEKVPTEVAFSDKTNFISLNQSAKEWAREIANVDISHRDSER
                     SILIKADYNIQTAYKILESKYYELFELIQRG"
     gene            410..1432
                     /locus_tag="L1V16_003028"
     CDS             410..1432
                     /locus_tag="L1V16_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide synthesis protein"
                     /protein_id="HBN1277289.1"
                     /translation="MTQKHSSIKRIIHRISEELNATRRIAKITSWKEAFATLQAKIDI
                     QVMNRNGYNESKKQKEHLLKKHEVMLKYYEKTFSDFLKTYDYSQNQIINQSKSPYSNC
                     IWVCWWQGLDQSPEIVKACVKSIKRNAGKHTVIILTEDNYRQYVDIPKWVEEKKNKGI
                     ITRTNYSDLLRLSLLAKHGGLWLDATFYCTKPIPDEYFDIDIWSIRRPDYAHASVASG
                     YFAGYSLACNQESRWMFAIIRDFFLNYWKNNDMMVDYLMIDYMIVLAQRINHEIAQTF
                     DKIPSNNPLCDELIKNLNNIYDEKVWNLLKKDTLLFKLTWKQSFKKQKDDKVTFYGML
                     VENKLL"
     gene            1454..>2441
                     /locus_tag="L1V16_003029"
     CDS             1454..>2441
                     /locus_tag="L1V16_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1277290.1"
                     /translation="MKHKVSVIVPIYNVEKYLRKCVDSLLSQTLKEIEIVLVDDGSPD
                     ASGEIADEYQKKYSNVKTIHRENGGLGPARNTGIENATGEYVAFLDSDDWVESDMYEK
                     LYLVASKENADIVVSGHCDFANDKAMVKKQHPLSGNVYDTPNSIKNVRKNLFGHSPKD
                     QEVEAFPMSVCMSLYNKNLLDKYRLRFEKILSEDTIFNLNAYDVANKIAFTEYTDYCY
                     RKEEQESITKSLSPNKQTEFKEFLITLKAIASKEDLECQIRAKRMAIDYCRLYVGLVD
                     DANLGIKEKRKYIKKFIEDEGLIQCWKGYPTNTLPFQQKFFHKMLECKCYTIL"
BASE COUNT          975 a          260 c          463 g          743 t
ORIGIN      
        1 aagaagaaat aaaaaattat gcaaagaaaa gtggcataga tgatgatatt aaatttttag
       61 gaaatagaaa tgatatagaa aaattttatc aagcatttga cgtattaatg ttgccatcat
      121 tatttgaagg ggttccgtta gtgggtattg aagctcaatt tgcagattta ccgtgtttct
      181 tttcggagaa agttcctaca gaagttgctt tcagtgataa gaccaatttc ataagtttaa
      241 atcaatcggc aaaagaatgg gcgagagaga ttgcaaatgt agatatctct catcgagatt
      301 cagaacgttc gattttaata aaggcagatt ataatattca aacagcatac aaaatcttag
      361 aatcaaaata ttatgagtta tttgaattaa tacaaagagg ttaaagaata tgacacagaa
      421 acattcaagt ataaaaagaa ttatacatcg catatccgaa gaattgaatg caacaagacg
      481 aattgcaaag ataacatctt ggaaggaagc atttgccacg ttacaagcta aaattgatat
      541 tcaagtcatg aatcgtaatg gatataatga aagtaaaaaa cagaaggaac atttattaaa
      601 aaaacatgag gtaatgctga agtattatga aaagactttt tcagattttt tgaaaacata
      661 tgattatagt caaaatcaaa taattaatca atcaaaatca ccatattcta actgcatttg
      721 ggtttgttgg tggcagggat tggatcaatc gccggaaatt gtaaaagctt gtgtaaaatc
      781 aataaaacga aatgcaggga aacatactgt tataatttta acagaagata attatagaca
      841 atatgttgat ataccaaaat gggtggaaga aaagaaaaac aaaggaatca ttacgagaac
      901 aaattattct gatttattaa gattatcttt gctagcaaaa catggaggtt tgtggttaga
      961 cgccacattt tattgtacaa aaccaatacc agatgagtat tttgatatcg atatttggtc
     1021 tattaggagg cctgattatg ctcacgcatc cgtagcatca ggatattttg cgggttattc
     1081 attagcatgt aatcaagagt ctagatggat gtttgctata attagagact tttttttaaa
     1141 ttattggaaa aataatgata tgatggtgga ttatttgatg atagattata tgattgtttt
     1201 agcacagaga ataaatcatg aaatagcaca gacatttgat aaaataccta gtaacaatcc
     1261 attatgtgac gaattgatta aaaatttaaa taatatatat gatgaaaaag tatggaactt
     1321 attaaagaaa gatactttac tgtttaagtt gacatggaaa caatctttta aaaagcaaaa
     1381 agatgataaa gttacttttt atgggatgtt ggtagaaaac aaattattat aaatattaga
     1441 ggtataaaaa gttatgaaac acaaggtaag tgtgatagta ccaatttaca atgttgaaaa
     1501 atatttaaga aaatgtgtgg atagtttatt gagtcagaca ttaaaagaga tagaaatcgt
     1561 attagttgat gatggttcgc cagatgcttc gggggaaata gcagatgagt atcaaaaaaa
     1621 atattctaat gtaaaaacaa tacatagaga aaatgggggg ttaggaccgg caagaaatac
     1681 aggaattgag aatgcgacag gagaatatgt ggcttttctt gattcagatg attgggtaga
     1741 aagtgatatg tatgaaaaat tatacttagt tgcgtccaaa gaaaatgctg atatagtagt
     1801 tagtggacat tgtgattttg cgaatgacaa agctatggtg aaaaagcaac atcctttgag
     1861 tgggaatgta tatgatacgc ctaatagtat taaaaatgta cgaaaaaatt tatttggaca
     1921 tagtccaaaa gatcaagaag tagaggcctt cccgatgtca gtatgtatgt ctttgtataa
     1981 taaaaatctg ctagataaat atagactaag atttgaaaaa attttatctg aagatacaat
     2041 ttttaacttg aatgcatatg atgtcgcaaa taaaattgct tttacagaat atacagatta
     2101 ttgttataga aaagaagaac aagagtctat tacaaaaagt ttatctccaa ataagcagac
     2161 ggaatttaaa gaatttttaa taactctaaa agctatagca tcgaaagaag atttagaatg
     2221 tcaaatcaga gcaaaacgta tggcaattga ttattgtagg ctttatgtgg gcttagttga
     2281 tgatgcaaat ttgggaatta aagagaaaag aaagtatata aaaaaattta ttgaagatga
     2341 gggattaatt caatgttgga agggatatcc tacaaatacg ctaccatttc aacaaaaatt
     2401 ttttcataaa atgcttgaat gtaagtgtta tacaatattg t
//
LOCUS       DAFLWQ010000186         2412 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.193, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000186 DAFLWQ010000000
VERSION     DAFLWQ010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2412
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.193"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            109..2262
                     /locus_tag="L1V16_003030"
     CDS             109..2262
                     /locus_tag="L1V16_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBN1277291.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          823 a          425 c          534 g          630 t
ORIGIN      
        1 tatcttgaaa ttaggtaaag aatttcttgc tccgcccatt ttttcttttt tattaagaag
       61 tttttgggta caatgaagca tgaatgtaaa taggcggaag gataggaaat gatgaaagat
      121 tttatgaaaa aaatattaaa tacttcttgg ttagaaaaaa taagaaaagg tgcacaagaa
      181 cctaagaaca aaacgtttcg ccggtcccat gttccttttc gcttaaattt tctttttttc
      241 attatattta cgttatttgt tgcgttgatt gctagattgg gttatttgca gatcgtgaac
      301 ggcgaagaga tggaggcgcg agtgaagtct acttctacga ttacggtcca agaaagtact
      361 cctcgcggaa tgatctacga ctccacagga aaagctttag ttacgaataa agcgaatcag
      421 gccatcacat atacgagagg aacacaagtt acggctaaag atttgcttga aatcgcaacg
      481 aagctgaact cgctgatcga tgttccggta gatgaaaatc tgacagatag agataaaaaa
      541 gatttttggc tggctgatcc caaacatttg aaagaagcca caaaaagact ttcggcaaaa
      601 gaaaagcaat tagggaacag cgaacaatat agtgcgatgg tcaataaagt cacagctgat
      661 gagattaatt taaacgagga gcaattaaaa attgctacca tctttaaacg gatgaatagt
      721 gcatatgaat taaacactgt ctatatcaaa aactctggtg ttactgatca agagttagct
      781 gttgtggcag aacgcgcttc tgaacttcca ggagtttcga ctggcacaga ctggacacga
      841 gaatataatg cagcaagttc actgaaaagt attcttggca gtgtgacgac tgaaaagcaa
      901 ggacttccag cagatgaagc agagaaatac ctagcaaaag gttattctcg gaatgaccgt
      961 gtaggacaaa gttatttgga aaaacaatat gaagatgtcc tgcaaggaac caaaacccaa
     1021 tatgaagttt cccttgataa tgaaggaaat gtttcgaatc aaaaagaaat cttctctggg
     1081 gaaaaaggtt ctaatttaat gttatctatg aatgcagaat tccaatcaaa agtagaagaa
     1141 attttgaaaa ggaattatca aacattgatc aacaacggca aagcacagta ttcgcctggt
     1201 gcttatgcag tggctatgaa tcctcagaca ggagaagtgc tagcaatgac tggtttcagt
     1261 catgaacaag gttccaaaga aatcaccgag aatgctttag gcacgattac tagcgccttt
     1321 gatccagggt ctgtagtcaa ggctggtact ttgacagcag gctgggcaag taacgcgatc
     1381 agcggaaatc aagttttgat tgatgagccg attcgtctgc aaggtgcttc agaaaaaagc
     1441 tctgtcttta atcgaagcgg acaagttgct cttgatgcag tcaaagcatc ggaattgtct
     1501 tctaatacgt atatgatcaa agtggcgtta aagatgttag gactagacta tacacctgga
     1561 atgggactac ctagtttaga tgaagaagct aaagcttatc agcaattgag agactctttc
     1621 aaagagtttg gtcttggtac aacgactggg atcgatttgc cgaatgaatc tcctgggatc
     1681 tcacgttctg ttgattatat gaagaagttc aatgcggata atggcaaaga atggtatgct
     1741 ccaggtaact ttaccgattt ggcatttgga cagtttgaca catatacacc aatccaatta
     1801 gctcaatatg cttcaacagt cgctaatggc gggaaacgag tacagccgca cctagtcaaa
     1861 gcgatctatg gcaatgacga aaatggaaac ttgggtgaag tgaagaaaga aattggcaca
     1921 acagtagaaa atacggtcaa tatttctgca gaaaatatgg cgatcctccg tgaaggattc
     1981 caccaagttg tccatggtac cgatccttac acaacagcca aaccattagc cagtgcgaaa
     2041 atggaccttt ccgcaaaaac agggactgca gaaacggttg cggaaggtca tccagatatt
     2101 gcgacagtca atagtaatat cgtggcatac ggaccaacag acaatccgga aattgccatc
     2161 agtgttgtct tgccgaactt attagacgaa caagaccaca taaacttgac gattgctaaa
     2221 gaaataatgg acgcgtatta tgatatgttc atggcaaaat aaaaaagagg tcgtgaaaaa
     2281 gccgcttagt ttcgagtatg aagaaaaatt ttgtgaaaat agcttctcac atttttgctt
     2341 aaatttgact tcataccgag aaactggctt ttgaacaccg tttactcggc aaaaaaggtt
     2401 gtgacaaaaa tt
//
LOCUS       DAFLWQ010000187         2397 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.194, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000187 DAFLWQ010000000
VERSION     DAFLWQ010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2397
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.194"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            206..2068
                     /locus_tag="L1V16_003031"
     CDS             206..2068
                     /locus_tag="L1V16_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1277292.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2068..>2397
                     /locus_tag="L1V16_003032"
     CDS             2068..>2397
                     /locus_tag="L1V16_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1277293.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          864 a          353 c          466 g          714 t
ORIGIN      
        1 aaaatttgaa aaagcgtttg attatttata ttacgactta gtgcaataaa aaacgctttt
       61 taacagtaca tgtagtcgtc tttataatag ataaactctg taatattagt taaaaagcta
      121 taagttgcac ttagttaagt gcaaacattt catattgtcg ttagtttaga aaacgcttat
      181 attagcaatg taaggagaga tgataatgca gcagctaaca aaaagagaaa ggcagctttt
      241 gatttacttg gtggaaatgt ctgaaccggt aacaatcaaa aagttggctg aaaaagaaaa
      301 tgttagtgtt cggacgataa aatacgatct agatgatata agagagtggc tgaatgagcg
      361 gaagcaagtc ctatatagca aacgtagtca gggaatttgg atgaatatta gtagctctga
      421 tcgaatcaaa ttaaaaagcg aattgatgga tgttaatcgt tttgaaatat ttgcagatca
      481 aagtctccga atcaaacgtt tactaattat gcttttagta acaaaagaag ctattactgg
      541 aatgaaaatg gccaacgcat tagatgtcag caaagatacg atcatgaatg atttagatgt
      601 gctggaaaat aattttctta aggaaggatt gaccttgaat cgtcaggcgc gaaagggttt
      661 ttggatcata ggagaagaac gtctagttcg attaacgatt gaagagattc ttcaaaaaga
      721 gttcacggat tatgacattt ataaattaat gtcattgtta ttgaatggcg gtgagactga
      781 atactttgaa atgtattctg ctactgctac acctatccaa gaggtattta atcaagtaat
      841 cattcgaatg cgacacttac tggaatttga aaatctagag aaactgaatt acgcggaatt
      901 actaaatatt ctgattcgag tgacaattgc taccgttcgc ttacgcaaag aggctacgat
      961 tggtcgttat caattggttg ctgaacaaga attagacaaa aacgatcttt cttatcgcgt
     1021 catgcagcag gtctttgatt attatcagtt gccactgttc gaggatgaat atcattatat
     1081 ctatagtgat acattcgaca cgattcacca gcaagacgtc atgaaactag ttgagaatgt
     1141 gatttataaa gtaagtaaag caatcaacca ttctttttat caagatccac aattgttgac
     1201 gaatctgtat gctcatttat ccatgcgatt atcgagaaag aaaaaatttg tcaatgaata
     1261 taatcctttt aaagaagata tcaagcagaa atacccggaa ttatttgatg cgatcaagca
     1321 agcagttcga caagaaataa gtgaacaaaa tattctgatc aatgattctt tcgtggcata
     1381 tattgcctta cactttttgg tttcctacga aagagaagaa gatctacgaa gcgttagagc
     1441 cgtctacatt tgttcaacag ggttgggtgt gactagtctg atcaagcaaa agatcaatga
     1501 agaattaaat aatatcacta tcgtggcatt tgcttcagta ttgaatgcgc aagaaatgat
     1561 tgctaccaaa gatcctgatt tggtgattag tatttttcca attaatggca tcgatcgtcc
     1621 tttcatcaaa gtccatccat tacccactga acaggacttg aaaaaaattc aacaaataat
     1681 aaaaaaaata cttgcttctt ccaatcagca ggaaaggcat aacttgaatc ttagagaaac
     1741 gtccatcaat aaagatactt tagaagactt tagcaaggaa ttgattttga aagcttatac
     1801 gatttatgaa cgtttacttg tcattttgga agcagaattg atccaagaat atcgagaagc
     1861 ttttttgctt catgtattct taatggttca tcgtatcaca tttgatcaac aatatatggc
     1921 agaaggtcgt caagtagacc agattatttt agacaaagga acactggtag gaaaaatcga
     1981 agcagttttt gcagaaaata atttaggaat caatcagtca gaaatcagtg cattattctc
     2041 atatataaaa gaaggagcgt caagttagtg aaaatgtcag acgaggcttt aaaaattatc
     2101 gaggaaagtc aaaatcggga aaagttaaaa caagtgattg atctaattga agagcgatta
     2161 gtagaacatg ctattgtacc aaccgagttg cagtggacca ttctaattaa tcacttgaat
     2221 gagatgctga aacgttctca aagaaaggaa acgattcccg tagtcgatcg ggatttgttc
     2281 aaagaagtat ccaaagaagc cataactatt tctgatgaaa tagttagaag tatcggtaat
     2341 ttaaccgatg atgaaatata tgttttgtcg attcattttg aaacagcaaa aaataat
//
LOCUS       DAFLWQ010000188         2395 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.195, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000188 DAFLWQ010000000
VERSION     DAFLWQ010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2395
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.195"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            316..570
                     /locus_tag="L1V16_003033"
     CDS             316..570
                     /locus_tag="L1V16_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBN1277294.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            571..888
                     /locus_tag="L1V16_003034"
     CDS             571..888
                     /locus_tag="L1V16_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBN1277295.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1447..2382
                     /locus_tag="L1V16_003035"
     CDS             1447..2382
                     /locus_tag="L1V16_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277296.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          861 a          339 c          453 g          742 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaatggatgt taacggaagt gtatggtgag tagttcactc gtattttgat atcgtttgta
      181 tatgttttca gcgttctaag tggcttattt tgtccaataa taatatggag tggaatccct
      241 taagaaacac cgttggcaat tgttgttata acatgttata atttattcat caaaaactaa
      301 aaggagtgtg ataacatggg aaaagaacta aaggttagaa agatcggcaa tagcgtggga
      361 gtgatccttc caagctctct tggattaaaa agcggagaca ttatccaagc caaacaagaa
      421 ggcaacttat tcatattaga tactactcaa atagcaaaag aacacgatcg caaattgatt
      481 gaagaaagtt tccaagactt tgagaaaggt ttaacagttt cagaaattga aatggtaaaa
      541 gctttcggaa aatacggctg gagtgaatag atgaaagagt acacgctagt ttattctaaa
      601 agttttcaga ccagccttga aacgataata gaagaatggg aaaatgagct tgctctttct
      661 ccagccagca taaaaagatt tgtaggtgcg atccagaagg ctttagaact aaccaaaaat
      721 tttccaacta tgcatgagga agtttccgaa atctatggaa tggatatccc aacatatcgg
      781 atcgtgatcg gcaaaagcta tgccttattt tatcggatcg accatgaaaa aaaagagata
      841 cttgtaggac gtattttcca atctaaacaa atgaaactag gcttttaaca ataattagga
      901 aaaagtcgct catcctctac aggtgggtga ttaatgccgc tcgatatggt tgttaaccgt
      961 cggttactcg aagattgata tataagactt agtacctttt tattttgctc catgttatgg
     1021 ccgaaggtct aaagatacaa tcattagtct agagaaaaat taagaaccgt aggaactacg
     1081 gggatcgctt ggtgaataag agacactgct attagtgaaa aaataagata tcaagtacgc
     1141 tctattccca aaaatttcgt gactttactc atgagaggtt caagtagtat atttttaatc
     1201 aaaattgacg taacttttaa taaatactac ctaaataagg tagtatttat ttttgtgttt
     1261 taaaagagga agtccaatat atctatggga aacttcttaa atattatgtt ggtacatgaa
     1321 aatatacatc cctgctagac tatttacaac attttacttt gtacgtattc ttgttttaaa
     1381 aggaatggga taaaatatag gtacaataac tatttgatgc taaatataat taatggagga
     1441 gagatagtga acatacttaa tgaaaaaaga tatgtatggt ttgctggtaa aaaatatatt
     1501 actactttca aaagattatc cgagttaatg cagcagactg ttaaaagtgc tatgcctgaa
     1561 ggatacaagt ttaattttgt tcaatcttca gtatctactg aaagtatcta tttttcaatt
     1621 ctttctgaga gtaggctttt tcattttaga ataagttctc atgtaaagaa aactgatgtt
     1681 gatatatata cgttccgtac aaataattat aaaaatttaa atgatttgag tagaagtatc
     1741 agtgaatatc tcaaggggaa tagctatctc aagattcgat tttcacatat attaatttta
     1801 ctaccatatt tgaatgagaa tttcacccta attcaagtag ataagtcttt cattgcctca
     1861 ggtaatcaag gaaatatgaa tattacaagt aacaaaacgt cacgtgtgct attggcgttg
     1921 atgggttacg gaattcttta tagagatgac caaaatggcc agattctaat aaatcgggct
     1981 gggcgttcat tattaatgaa atatagaaaa tttataccgg aagattttca aaacttacag
     2041 ttagaaaaca tgcgtttaga agatttattt agattagcag aagatgataa gtatagattt
     2101 gaagttttga aaattcaaaa gaatgaacta ttgaataagt tatatcctga gaatgcgata
     2161 aaagcacatt ttggtgatgc taatcatatg tatagttggt tcattcctaa aagatttaga
     2221 gggaaaatca atgctggaga tcaagtgaaa gtactcaatc gaaatagtac agatgtcgta
     2281 atgataacag atatctatgt agaagatgaa gatataatca aatatatgaa gcctgtgata
     2341 aaacttgtta ataaaaataa aggaacccgt ggtgctagtt aattttttcc tagag
//
LOCUS       DAFLWQ010000189         2308 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.196, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000189 DAFLWQ010000000
VERSION     DAFLWQ010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.196"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            150..>2308
                     /gene="acm"
                     /locus_tag="L1V16_003036"
     CDS             150..>2308
                     /gene="acm"
                     /locus_tag="L1V16_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HBN1277297.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYK"
BASE COUNT          907 a          351 c          449 g          601 t
ORIGIN      
        1 gcatatttat tttttataaa tatttgtaaa ataactatca attttttagt taaaagattg
       61 gaaatgagtg ggggaggaat tgaagaaagg atttttgaga gatgatatag taggttttat
      121 ttttagttaa aataggggag atagaaaaaa tgaaaaagtg tagaaatatt attttatcaa
      181 tgttatttat tattactaat ataacatcac tgattcctgt tcatgtctat gcggatgcag
      241 gcagagatat cagcagtaat gtcacttcgt tgaccgtgga cccaacgaat attacagatg
      301 gaggaaacat aaaagtaaaa ttctcgtttg acgaaaaaaa acaaaatatc caaccaggtg
      361 attatctttg gatcaattgg ccaagtgaag gaaatattcg cggtgaagga ttccaaaaag
      421 aaatcccatt aatgattgaa aataaaaatg ttggaacttt aacggtcaga aaagattctg
      481 cgcaggttgt gtttaatgaa aatattaaaa acctagactc agtagaaggt tgggggcaat
      541 ttgagataca ggccagaaac gtaaccgata ccggtgaaga aaatacggga ccattcaccg
      601 tgacgagcgg tgataaaaca gctactgtaa atgtgacaaa gccagcttct ggttcttctt
      661 ctagcgtttt ttattataaa acaggagaca tgctacctga agatactaag cacattcgat
      721 ggtttttgaa tattaacaat aacggcactt atgttgaaca accagttaaa atcagtgatg
      781 aaatccaaag tggacaaaga ttagatccaa gtacgtttga aattaatcaa atacacttag
      841 gtgaacagaa ggtttataga ggagaagagg gaatccaaca atttttacaa gatttcccca
      901 gcgctacatt taatttttca gtaactgata attacattga aataactata ccaaaaaact
      961 ttgtcaatct taggaaaata atggtgagtt ataagacgat catagaaaac ccagaacaaa
     1021 taaattttga gaatcattcg gaagcttggt ttaaagaatt taataaacct gctgttgatg
     1081 gagaaagttt caatcataca gttaaaaata tttcagcttc tggtggagtc aacggtacag
     1141 ttagaggcga attgaagatt ttcaaatata tcaatgacac agagattggt atcccaaatg
     1201 tgactttcga attaagacga gcagatgaac agcctattca aggacagtct agtatcctgt
     1261 tgacttcgaa tgaacaggga gaagctagta tcaaaggcct gcaagtagga gactatgttg
     1321 taaaagaaaa agaagcaccc aattggattg attttgatcc actaagttca aatgaactca
     1381 aattctccat aaacgaaaat gatacagagg gagtcagttt acctatttat aacaagaaaa
     1441 aggttacgaa catcacagca actaaaattt ggaacggtgg aaccactcca agaccgagta
     1501 tttattttaa attattcaga gcaagtacaa acaattggga accagttcct gatgcagaaa
     1561 caaaacgatt agacaatgga ataacttcag tgacttggga agatatccaa cagtatgatg
     1621 atagtggaaa cgaatatacg tttaaagtgc aagaagtaga tcaaaacgga aatgattatg
     1681 tcccttcagg ttatcaaaaa attgaaaacg ggctagtcgt tacaaatgag aataaagaag
     1741 tcatttcagt ctcaggacaa aaaacatggg aagacaatga gaaccaagac ggcaaacgac
     1801 cgacgacgat cacagtaaat ctattagccg acggtcaacc gatccaacac aaagaagtaa
     1861 gtgaaaaaga tgattggcgc tatcgtttca caaatctgcc aaaatacaga gacgggcaag
     1921 aaatcatcta tactgtaacg gaagacaacg tgcccgaata cagtacgacg attgacgggt
     1981 ataacatcaa aaacagttat acaccggaaa aaacaaatat atctatacca ggtagccata
     2041 taacaccgtg gaaaaatttt ccagagaaga cagagagaga gaaaattaga aatctattct
     2101 ctcaaaaatt gcaaatattt gctcatacag gagaatccag cgaacaaaga agcaattata
     2161 ttagtaagag agctgtacct aaacagataa caaataaatc aaaaagcatt cttcctaaaa
     2221 caagtagtaa aaaatctagt tttgctgtaa tcattggttt attgatagta actatctgtg
     2281 ctgggatatt cttacaaaaa tataaaaa
//
LOCUS       DAFLWQ010000190         2251 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.197, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000190 DAFLWQ010000000
VERSION     DAFLWQ010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2251
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.197"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..612
                     /locus_tag="L1V16_003037"
     CDS             <1..612
                     /locus_tag="L1V16_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBN1277298.1"
                     /translation="DTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVS
                     INMKGLKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDY
                     GRQGRQRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMNFDEMKKIALDYREAFG
                     TIKQDQLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            628..1407
                     /locus_tag="L1V16_003038"
     CDS             628..1407
                     /locus_tag="L1V16_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HBN1277299.1"
                     /translation="MEETISLKEIFETLRKHLVIIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKDAISVNQAENSQMFSIQAISTNAVAAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLMTGLMLGMMVGVGLAFLLELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAQTQPKATNDKTAPSRRSRSRV"
     gene            1419..2117
                     /locus_tag="L1V16_003039"
     CDS             1419..2117
                     /locus_tag="L1V16_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HBN1277300.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVDNLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            2145..>2251
                     /locus_tag="L1V16_003040"
     CDS             2145..>2251
                     /locus_tag="L1V16_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBN1277301.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGIT"
BASE COUNT          802 a          438 c          482 g          529 t
ORIGIN      
        1 gatacgtatg tcgacatcgt aggtcgtgac acaaaagaca agatcaacca cgcttacgca
       61 ttcggcggag ctgccatggc gatggatacc gtacaaaaat atgtagacat cccaatcgat
      121 cactatgtct ctatcaatat gaaagggcta aaggaactcg ttgatgcagt tggtggtatc
      181 gaagtcaata atgacctcac tttctcacaa gatggctatg actttccaat cggtaaaatt
      241 acattgaacg gggatcaggc attatcttat tctcgtatgc gttatgaaga cccaaatggt
      301 gattacggta gacaagggcg ccaaagaaag atcgtagaag gcgtagcgaa aaaagtattg
      361 agtctaaacg gtgtcagcaa ctatcaatcc gttttgaatg ctctagagtc gaatatgaaa
      421 acagacatga actttgatga aatgaaaaaa attgctttag attatcggga ggcatttggt
      481 acgattaagc aagatcagct gcaaggagaa ggcttcatgc aagataatat ctcctatcaa
      541 aaagtcagtg atcaagaact tgatcgtgtg aaaaaagaat taaaagatca aatgaatcta
      601 gagaataaat aggaaagtgg agaaaaaatg gaagagacaa tcagcttgaa agaaattttt
      661 gaaacattac gcaaacactt ggtaataatc atcatctcaa tgtttgctgg cttggccatc
      721 tcaggaatcg taacattttt catcttgaca ccaaaataca gttcacaagc acaattgatc
      781 gtgacactgc cacaatcaga cactgcaaat gtcaatgatg tcaatacgaa cctgcaaatg
      841 atcaatacgt ataaagatat gatcgtcagt gatttagtgc tcaatgaagt caaagatcgt
      901 ttagaaacag aagacaatgt gaaaatgact gctgaacaaa tcaaagatgc catctcagtt
      961 aatcaggcag aaaattcaca aatgttctcg attcaggcaa taagtacgaa tgcagtggct
     1021 gctcaacaga tcgctaacac aacttcacaa gttttccaag agaacgcaaa agatgtgatg
     1081 aatgttgata aaatctcgat catttcaggt gcagttgcca atacgacacc tgtttcgcca
     1141 aataataaat tgaatttaat gactggctta atgttaggaa tgatggtagg tgtaggtctg
     1201 gcattcttat tggaattact cgatcggaca gtgaaagatg aaaaatatgt gacagataca
     1261 ttaggattcc caatcttagg aacagttcca gaaatgtcag cgaaagaatt gaatgctggt
     1321 atccgtaaaa aaggaccagc tcagacacaa ccaaaagcta caaacgataa aacagcgcca
     1381 tcacgcagaa gccgctcaag agtctaggag gaaagaaaat ggcacgaaca cagaaacaaa
     1441 aagcagccca aactcatgca gtcagtttgg tcacactcac caatccctct tcaccaatcg
     1501 ctgaacaata tcgtacgatt cggacgaata tccagtttgc ctccgcagct ggtcagcaaa
     1561 tcaaaacgat tgttgtgact tcatcaggac ctggagaagg gaaatcgacc actgcagcaa
     1621 acattgccgt tgtttttgcc aaatctggtc aacgggtgct gctagtcgat gcagacttac
     1681 gtaagcccgt catctataaa acgttcaagt tgaacaacgc aagcggatta agtactgttc
     1741 ttagttcatc aggaagtgta gcagatgaga tccaacgaac accagtcgac aatttgtcga
     1801 ttctgccaag tggacctaaa ccaccaaatc catcagaact actaagttcg ccaagaatgg
     1861 atcagatttt agcagaagca agacaactat ttgatgtagt gatcttcgac atgccgccag
     1921 tcgttgccgt aacagatgca cagatcatgt cttcaaaaac ggatggcacc ttattggtcg
     1981 tacgggaaaa tacgtcacga aaagaatcat tgactaaagc aaaagaactg ttagatatgg
     2041 tacaagcacg agtcttaggt gtcgtataca acggagcaga acacagcaaa gatgctggtt
     2101 attactacgg aaattaagga ataagaagag aggagacaag agaaatgatc gatctacatt
     2161 gccatatcct accaggaatc gatgacgggg cagaaaactt agaagcaagt attgcaatgg
     2221 ctgaaaaagc gattcagcaa ggcattacgc a
//
LOCUS       DAFLWQ010000191         2154 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.198, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000191 DAFLWQ010000000
VERSION     DAFLWQ010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2154
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.198"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..515
                     /locus_tag="L1V16_003041"
     CDS             <1..515
                     /locus_tag="L1V16_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBN1277302.1"
                     /translation="YVDIPIDHYVSINMKGLKELVDAVGGIEVNNDLTFSQDGYDFTI
                     GKITLNGDQALSYSRMRYEDPNGDYGRQERQRKIVEGVAKKVLSLNGVSNYQSVLNAL
                     ESNMKTDMSFDEMKKIALDYREAFGTIKQDQLQGEGFMQDNISYQKVSDQELDRVKKE
                     LKDQMNLENK"
     gene            531..1310
                     /locus_tag="L1V16_003042"
     CDS             531..1310
                     /locus_tag="L1V16_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HBN1277303.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            1322..2020
                     /locus_tag="L1V16_003043"
     CDS             1322..2020
                     /locus_tag="L1V16_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HBN1277304.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAS
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQVLAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENMSRKESLTKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            2048..>2154
                     /locus_tag="L1V16_003044"
     CDS             2048..>2154
                     /locus_tag="L1V16_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBN1277305.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGIT"
BASE COUNT          769 a          417 c          457 g          511 t
ORIGIN      
        1 aatatgtaga catcccaatc gatcactatg tctctatcaa catgaaaggg ctaaaagaac
       61 ttgttgatgc agttggtggt atcgaagtca ataatgacct cactttctca caagatggct
      121 atgactttac aatcggtaaa attactttga acggggatca ggcattatct tattctcgta
      181 tgcgttatga agatccaaac ggtgactatg gtagacaaga gcgtcaaaga aagatcgtag
      241 aaggcgtagc aaaaaaagta ttgagtctaa acggtgtcag caactatcaa tccgttttga
      301 atgctctaga gtcgaatatg aaaacagaca tgagctttga tgaaatgaaa aaaattgctt
      361 tagattatcg ggaggcattt ggtacgatca agcaagatca gctgcaagga gaaggcttca
      421 tgcaagataa tatctcctat caaaaagtca gtgatcaaga acttgatcgt gtaaaaaaag
      481 aattaaaaga tcaaatgaat ctagagaata aataggaaag tggagaaaaa atggaagaga
      541 caatcagctt gaaagaaatt tttgaaacat tacgcaaaca cttggtaaca atcatcatct
      601 caatgtttgc tggcttggcc atctcaggaa tcgtgacgtt tttcatcttg acaccaaaat
      661 acagttcaca agcacaattg atcgtgacac tgccacaatc agacacagca aatgtcaatg
      721 atgtcaatac gaacctgcaa atgatcaata cgtataaaga tatgatcgtc agtgatttag
      781 tactaaatga agtcaaagat cgtttagaaa cagaagacaa tgtgaaaatg actgctggac
      841 aaatcaaaga tgcgatctcc gtcaatcagt cacaaaattc acaaatgttc tcgatccagg
      901 caataagcac gaatgcagtg actgctcaac agatcgctaa cacaacttca caagttttcc
      961 aagaaaacgc caaagacgtg atgaatgtcg ataaaatctc gattatttca ggtgcagttg
     1021 ccaatacgac acctgtttcg ccaaataata aattgaatct agtgattggc ttagtgttag
     1081 gaatgatggt aggcgtaggt ttggcattct tattcgaatt acttgatcgg acagtgaaag
     1141 atgaaaaata tgtgacggat acattaggat tcccaatctt aggaacagtt ccagaaatgt
     1201 cagcgaaaga attgaacgct ggtatccgta aaaaaggaac agctcctgca cgaccaaaag
     1261 ctacaaacga taaaacagcc ccatcacgca gaagccgctc aagagtctag gaggaagaaa
     1321 aatggcacga acacagaaac aaaaagcagc acaaactcat gcagtcagtt tgatcacatt
     1381 aacaaatcca tcttcaccaa tcgccgaaca atatcgtacg atccggacga atatccagtt
     1441 tgcctccgca gctggtcagc aaatcaaaac gattgtcgtg acttcatcag gtcctggaga
     1501 agggaaatcc accactgcag caaatattgc agtcgttttt gctaaatcag gtcaacgagt
     1561 tctactagtc gatgcagatt tacgtaaacc cgtcgtctat aagacattcc agctgaacaa
     1621 tgccagtgga ttaagtacag cacttagttc atcaggaagt gtagcagatg tgatccaacg
     1681 aacgccagtc gagaacttgt caattttgcc tagtggacct aagccaccca acccatcaga
     1741 attgttaagc tcgccaagaa tggatcaggt tctagccgaa gcaagacagt tatttgacgt
     1801 ggtgatattc gatatgccac cagtagtagc cgtaacagat gcacagatca tgtcttcaaa
     1861 aacggatggc actttattgg tcgtacgtga aaatatgtca cgtaaagaat ccttgactaa
     1921 agcaaaagaa ctgctggaga tggtacaagc acgagtctta ggtgttgtgt acaacggagc
     1981 agaacatagc aaagatgctg gttattacta cggaaattaa ggaataagaa gagaggagac
     2041 aagagaaatg atcgatctac attgccatat cctaccagga atcgatgacg gggcagaaaa
     2101 cttagaagca agtattgcaa tggctgaaaa agcgattcag caaggcatca cgca
//
LOCUS       DAFLWQ010000192         2113 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.199, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000192 DAFLWQ010000000
VERSION     DAFLWQ010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2113
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.199"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(559..924)
                     /locus_tag="L1V16_003045"
     CDS             complement(559..924)
                     /locus_tag="L1V16_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277306.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1000..1245)
                     /locus_tag="L1V16_003046"
     CDS             complement(1000..1245)
                     /locus_tag="L1V16_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1277307.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1315..1569)
                     /locus_tag="L1V16_003047"
     CDS             complement(1315..1569)
                     /locus_tag="L1V16_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277308.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(1733..2056)
                     /locus_tag="L1V16_003048"
     CDS             complement(1733..2056)
                     /locus_tag="L1V16_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277309.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
BASE COUNT          791 a          361 c          371 g          590 t
ORIGIN      
        1 tttcgtctga aaacaaaaaa agaaagcgtt attattttag tctattttca gggggggaac
       61 cttatgataa aaaaactatt tttactatca atattaacgc tagcaatggc aggttgttct
      121 gactctggct tagcaactga actgatcaca aaatcaactg aagccacgac agaggagtta
      181 aaatgtggaa acgatcacag tgactacaga ggcttaaatc gacgatgcat gggaatatta
      241 ggcagaagca attgtaagca tcgatgtagt aatcgaagaa ggtgtagaag aagcaacaga
      301 aaaatcaaaa gaaagatcaa aagaagcaat ctgtgctgtg catcgtatac agacgtcgaa
      361 gatgcggtac ttttaaacca cgtcaggaga tgttcattta tgtctaggga agttggcgat
      421 gaaccaaaac tagagtacgc ttttagtttt gcacgtgagg atgaagataa ccctaaaact
      481 tacgacattt tagcttgatc taagatggtt aaagcttttt aatgaagtaa gaggagatag
      541 aaggcttttc tagttatatt aggtaagata aattcctttt tgctccaaat ttgctaaaca
      601 ttctgctaga taaacttcat cgtgttccgg ataaatcggc acgttgcgct ctacagtagg
      661 taaatcaaaa aatgcttcgc atgatttgcc acgatacata ggatttttcc actctggtgc
      721 tgggctgtaa ccacgttttt ccatttcatc catgacaagc tgatgatatt ggaataatct
      781 ataaggagaa tagtgaaaaa cataatccac agtagcatgt ttctttcccc agccatttcc
      841 tcttaatgca cagcattccc gatgttgtcc taaaagctgt tgacgaggaa gctttgaaat
      901 caatttttca tgccataatc gcatagaaat gtctccttta tatatagatt gttaacctta
      961 gacgttaaat gaaaaaacca gcaccaaggc tggaaaaaat cacttcagtt tgcttgctgt
     1021 ttctgagcga ccaattaggt aatcaacgga aatatcgtaa aagtcagcga tatagattaa
     1081 ttcaatgatg cttggaattt cttctccttc ttcgtactta cgatatttga ataaaggaat
     1141 acttaacgcg ctagaaacag ctacttgaga taaagatcgg ccagttctta agaaattcag
     1201 acgacaacgt aaagtatcca gtaaaatagc ttcttcgata ctcatttaat cacctttcat
     1261 tatagtagaa tagttataat gactatagaa agctacacat gcaatcaata gtactcaatg
     1321 ttttttattt aaacgtatca aataaagaat gacgatcaat aaagacaaaa ccagtcctga
     1381 taattcttct ataaaaacac tatcgggttc aaagtagttg taattaaaaa ctttccacat
     1441 aaagtagata gccggaagag tcaaaatagc taaataaaac cgttctttgt tccaattcat
     1501 aagataaaca atacttgcga ccagtgcgac cgcaggcacc caaaacaaaa ctctcaccaa
     1561 cgtaatcatg taacggactc ctcaacgatt catataataa aagataacat gttattgcat
     1621 acatcacaaa tgaaatgcta ggaaaataaa agaagaatag atcaatgaaa aatgaaaaag
     1681 cagaacagtt ttctgctgat aagcaggaac tgttccgctg aatgtgtctt atctatcgag
     1741 aaaaaatcaa tggattgata tctaagtaat tcaatacata taaaaagagg acgatcgcat
     1801 tcactaaaaa ggaaagaatg atgatcccat agcgaatgga aacatattta acaaatactt
     1861 ttgtttgaat acgggcatat ctttttcctt tatagctgag catcatgaca agaagcaaaa
     1921 gggtaatcac accttgaaaa atcattccaa taaacagaat tcctgaggtt tgataattta
     1981 attggagaaa ataagctgct gccgcaacta aatcgaataa aatcgcaata aatggcaaaa
     2041 taatcactcc taacattgag aataaataaa agaataacat tttttctaaa ataagcaaat
     2101 aaaaattaaa gta
//
LOCUS       DAFLWQ010000193         2097 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.200, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000193 DAFLWQ010000000
VERSION     DAFLWQ010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2097
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.200"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..424)
                     /locus_tag="L1V16_003049"
     CDS             complement(<1..424)
                     /locus_tag="L1V16_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBN1277310.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQI"
     gene            complement(533..1564)
                     /locus_tag="L1V16_003050"
     CDS             complement(533..1564)
                     /locus_tag="L1V16_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1277311.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT          652 a          337 c          360 g          748 t
ORIGIN      
        1 gaatctgttt tgattttgtt ccatttgaaa tttctctcac tcgctttttt gtctcatcat
       61 caaataaaat gaaagggtct tctaaacgat cgataaatac ttccattgtt gttgttggta
      121 gatgataaga agtcatgaca ggcactgcac caaggtaaga cacagaaaca gctagaaggt
      181 atgtgtcaaa agcggaactc ttataaataa taactttgtc tccggatttc actccaagat
      241 gagccaattg ataagcccgt ttcaacacac tttcgcagca ttttttgtaa gttgtttcaa
      301 gtcctaattc tgggaaagct gaaagtggct catcaaagat aatcggggtc tcggaaaagt
      361 tagctgcagc ttcttgaaaa ttcgtaaata agttcaaagg ggaatacgtt atggtctcca
      421 tcattcacac tccattatct tttgttaagt aatatacaaa ttcaagataa tcgtaacata
      481 atcctttata taataacata gtttattgtg aaaaaaagat catacatttg ttttatatgg
      541 aagaaacccg aacgaatgcc gctaattcgt gataagaaaa atcaaccatc ttttcccaga
      601 tatcttgaaa agaatgggat gagaggtatc gattaccaca taaataattt accgcgtcag
      661 catcatctaa atatagttct gcataataac gatatgtttt tctgcatagt tctggcgata
      721 cgtttttata tactgtaatt ttgctcaaaa tttggcgaat agtccgagga gaaatttgct
      781 gatcatgtga ggaacgaaaa acaaaagaat tttcgtccgt attttgtgct gttaacttaa
      841 aatagttctc cagaaatggc atcgcttctt ttggtattgg tactttattc agtctgtttt
      901 cttttctatt cagattaaga atctgcttgg tcaaagatac atctttacgt ttaagttcta
      961 ctacttcatg gatctttaat ccgcaataca gaagaatggc agtaattgca aggttcctcg
     1021 gtctattctt ttcttcaaag ctagcttctc tgcttgtttg aaagccttca atcgggataa
     1081 acaaatgctc aaaatctttg aaaagttctg catcgatata tcgcggagct gctttggttg
     1141 tttccggtaa acttgtaccc aaaagagaaa tctcttcttc aatcagtcct ttttgataca
     1201 aaaatcgtaa aaaatgattt aatgaatatt gcttccttga aatcccgtaa tagctatttt
     1261 caaacaattg ctccgtttct tggttcgctg tagtttggaa cgaacgagta tgtcgataga
     1321 ttttagctaa gaaattctga taatcttgtt tttctaaatg gataatcagc tgatcatcca
     1381 cttcttcaga aaatactttt ctcaaataat cagtaaacag atgaaaatct tttgcgtatt
     1441 catagcgact gcctaatgaa agggaagaac gattttcttc taaaaactgt tgaaagacgg
     1501 aagggagcaa gtgtgtacgt tgctttaact tttcttgcag ttgttttcta gttttgctgt
     1561 ccattacaaa ttccctccaa tagtgttcat tttctatatt ttaccgcatt tcatcaaatg
     1621 aagatagaca gtttgtcttg atcttaggaa gcaaattttt aactaagtac tagctaaaag
     1681 atatgaagta agaagataca tttttagtta ttttattagt gcagtcattc ttttgatctt
     1741 ttaattgatt tatcctcttt ttagctatgt ggttacttca tgagcaatga aatggatttg
     1801 gttcgttcta atggcaggag gctctttctt ttatttccga aaaattagaa aacatttttt
     1861 cagaatcgat tggctctcca tttattcaat aatggtttgt ctaacgatat tgttgggata
     1921 attcttaaag aagtattaga aatagttggt acttcattac tttacatgaa gatttattct
     1981 atggtaggag caattatatt gagaattaat ccttttttat ataagttgtt tgcttattga
     2041 tggattggat aaattaaacc atcacaacga gtggaaatta tatgaaattt ttcataa
//
LOCUS       DAFLWQ010000194         2064 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.201, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000194 DAFLWQ010000000
VERSION     DAFLWQ010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2064
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.201"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(51..1598)
                     /locus_tag="L1V16_003051"
     CDS             complement(51..1598)
                     /locus_tag="L1V16_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBN1277312.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="L1V16_003052"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="L1V16_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBN1277313.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
BASE COUNT          581 a          431 c          371 g          681 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagt
//
LOCUS       DAFLWQ010000195         1967 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.202, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000195 DAFLWQ010000000
VERSION     DAFLWQ010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1967
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.202"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            270..836
                     /gene="amaP"
                     /locus_tag="L1V16_003053"
     CDS             270..836
                     /gene="amaP"
                     /locus_tag="L1V16_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBN1277314.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            849..1037
                     /locus_tag="L1V16_003054"
     CDS             849..1037
                     /locus_tag="L1V16_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBN1277315.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1050..1607
                     /locus_tag="L1V16_003055"
     CDS             1050..1607
                     /locus_tag="L1V16_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBN1277316.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1639..1881
                     /locus_tag="L1V16_003056"
     CDS             1639..1881
                     /locus_tag="L1V16_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBN1277317.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
BASE COUNT          716 a          305 c          404 g          542 t
ORIGIN      
        1 aaatagaatc ttgtaataat aactgagcat aatctttgca atttttaatc ttgaataata
       61 tcctttaagt atagccagca atcaaaagta aatagagaat aagtaagcaa ttgttatttc
      121 agtatcagac tggcaataaa acgccgttat gatccagcaa tgtttggtag cgctttattt
      181 actgatgcta tgctaactgt tcgctatcta tactgtgatt gtcggtagag ttatttacag
      241 ggtaaaaata agtttatagg aggtggaaaa tgaataaggg gttaaaaata atcggtgtta
      301 tcatgagttt actgctactt tcagtatttc tagcgattgc gttgatcaat gcgccgtata
      361 ttatgcctga acaattggaa cgatttcgct tctttacttt aacgaattac tacatgcaac
      421 aatatatttt ctgggcagct gtagtatttg ccgttcttgc tattatcatc ttgctagtcg
      481 ttcttttcta tccaaagtca agaggaactt tcgttatgaa acgggaagat ggcaaactaa
      541 caatcgacaa aaaagcgatc gaagggttgg tacgttccca tttacacgaa gaagagttca
      601 ttcattcacc taaagtacgg atacgttcaa cgaaaaatcg aatccatatc catgtcaacg
      661 gagacttgaa acgaacttct tcattagtag ggaaaacagg tgtattgatg caagatatcg
      721 aagaagaagt aactaaagta ctcggaacaa aagaaacggt caaagtggca gtcacataca
      781 gcggttatga agaacaagaa gatacaagag actacaagca ctctcgagtg gaataggagg
      841 gccaaataat gaaagaacta ttttcagcat acaagctccc tattatcttt gggggtcttg
      901 gactactgct agctgtttta tggttaacga ttggattttt caagacattg ttgatcataa
      961 tcatgacagc aattggcgca ggaatcggtt tttatttgaa acagtcagga atagttgatc
     1021 aattttttaa atcataggag gaaacaaaga tggaaaacaa aaacatgaat acaacaaatg
     1081 gatcagtttt ggcaaatgaa aaaggagaaa accgcatgat gaatggtgaa ttgacttatg
     1141 aagacaaagt catccaaaaa atcatcggtt atgcattgaa agatgtagat ggtctattga
     1201 cattagatgg cggatttttc tcaaatatgg ctgaaaaatt agtcaacaca gataacgtaa
     1261 cagcaggtat caatacagaa gtaggtaaga aacaagtagc tgtggatcta gatgtgatcg
     1321 tagaatacgg taaagacatc gaagatattt acaaccaaat caaagaattg atcagtactg
     1381 aagtaaacaa tatgacacat ttagatgtta tcgaagtgaa tgtgaatgtt gcagacatca
     1441 aaacacaaga agaataccaa aaagatcaag aaacagtaca agacaaagta acagaagcag
     1501 caaaatccac aggacaattt gcttcacgcc aaacagataa agcaaaatct gctgtaggca
     1561 aaggtgcaca aaaagtcaaa gaaaataacg aaccacgtgt acaataagaa gtaagaagtc
     1621 agttaggagg aatttaaaat gggatttatt tgggcattaa tcgtcggcgg tatcattgga
     1681 gcaattgcag gagcaatcac gaataaagga tcatcaatgg ggatcatcgc aaacatcatt
     1741 gctggtttag taggttcagc aattggacaa gctttactag gaacttgggg accaacaatt
     1801 gcaggaatgg ctatcattcc atcattgatc ggtgcaatca ttttagtatt agtcgtttca
     1861 ttctttgcac gtaaattata agcaaattga agaaaaactt atgttgaaat gaagaacaaa
     1921 tttgagaacc gtagcgacac tcgctgcggt tcttttttat atatttt
//
LOCUS       DAFLWQ010000196         1944 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.203, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000196 DAFLWQ010000000
VERSION     DAFLWQ010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1944
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.203"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            194..712
                     /locus_tag="L1V16_003057"
     CDS             194..712
                     /locus_tag="L1V16_003057"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBN1277318.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            840..1523
                     /locus_tag="L1V16_003058"
     CDS             840..1523
                     /locus_tag="L1V16_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBN1277319.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1832..1905
                     /locus_tag="L1V16_003059"
     tRNA            1832..1905
                     /locus_tag="L1V16_003059"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1866..1868,aa:Arg,seq:tct)
BASE COUNT          665 a          296 c          392 g          591 t
ORIGIN      
        1 aaacttgtaa tgttagggta aacgtttttt aaactaacgt caattattta taataaaaaa
       61 tgagataaag atgaggaaat agaattagaa acatataatt attaaaggga aacattttta
      121 cagctataat ttgaaaaaat ttatcgttat tatatgatta agaaggattg aataaagaaa
      181 gaagttgaaa acgatacctg attacaaaaa aataactttt ataagttcta taacgttgat
      241 tatattttta attcttattc ttctcgtcgt cttggttccc cgaatttttg gtttgactcc
      301 ttatattatt gaggacaaag aaatgagtcc atattatgca caaggaaatc tgatatatgt
      361 acgaccgaaa aatacaaatg agattttagt cggagatatt attacatatt atgaaaattc
      421 aggaaaaaaa atctcgacgc gtcgcgtaat agccgttgaa aacaaccacg aagattttta
      481 tacaaaagct gatacaaaga cttatattga gcctggagta gtaaaaaaga gaaatattat
      541 cggtagtccc atctttcaga ttccatatat tggactagtc ctttcaaaaa cggcatttgc
      601 atggattcag gggttattct ttacgattgc tttttgccta acaggaatca cagcatggaa
      661 tacctttgta gagttgaaaa agaagcggag acgaacacag aaatttttgt aagaatgtta
      721 aaaacataaa tgtattccag agatccaacg actcttctga acatgaaaca cgagaaaaca
      781 ctcatgcagc ttgtagattt agtcagttgt tcgtataatg tgtgaagagg aggagtagta
      841 tgcgcaatga aatgatgcat cgtcctgtag tcaaagaaga actattggat tttatgcgta
      901 cccagcaaaa aaaattaccg ggtgagctag gcaaactgga agaagaagct catgtagcag
      961 aagtaccagt tattccccat gaaacagttg tatttttgaa atttttactt ggacagcttc
     1021 agcctgaacg aatcttggag atcggagcag ctatcggttt ttcatcaagt gtcatggcca
     1081 cgacaatcgg agaaaacgct catgttacga caattgatcg tttcgatgtc atgatcgaga
     1141 aagctaaaaa aaactatgaa cgtctaggac tgacagataa agtgactttg cttgaaggtc
     1201 aagcagcaga tatcttgccg gagttgtctg gtccgtatga ctttattttt atggatagtg
     1261 caaaatcaaa atatattgaa tttttacctg aatgcttacg tttgttaaga aaaggtggcg
     1321 ttttgatggt agatgacatc ttccaaggag gaacgatctt gctcccagat gaagagattc
     1381 cccgtggcaa acgagctatc catcgtaaat taaatgaatt tcttcgtgtt gtgatggatc
     1441 atcccgattt gacatcgaca atcttgccat taggtgatgg tgtgatctta atgacaaagg
     1501 aatcagaaac aatcgagttg tgatacatga ttatggcagc ctgtagataa tcgattgaat
     1561 cgagggctca attcgaactt gatgtaaaag tttctatatt tgtaagtcaa ttaaaggata
     1621 caggaaatct aaataaacag gagtagcatg aagtcaatgt agctcctgtt ttcaattgat
     1681 aaccttagaa cagctgaagg agaatgtctc gttttaaaag attgatttag tagttgggcc
     1741 aaaataattc attatttgct aattaaataa ctatttcgta ttgacagaag caatttaatt
     1801 atctataatt attgatgttc cgctgattct tgtcatagta gctcagctgg atagagcatc
     1861 cgccttctaa gcggacggtc gggggttcga atccctcctg tgacgctaaa aaaccgttag
     1921 aaactgaggt ttctaacggt tttt
//
LOCUS       DAFLWQ010000197         1821 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.204, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000197 DAFLWQ010000000
VERSION     DAFLWQ010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1821
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.204"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            275..1753
                     /locus_tag="L1V16_003060"
     CDS             275..1753
                     /locus_tag="L1V16_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1277320.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
BASE COUNT          662 a          253 c          325 g          581 t
ORIGIN      
        1 taaaagagca ggacggtggc cgtcctgctc ttttttgtgg ttgtttacgc aaatggcgca
       61 aatcttgtac attttaacac aataaaacaa aaaatataga atatttcctc ataaattttt
      121 ccattttttg caatattctc aaaaaaaaga taaaaaatga gaataactga tgaaaaaaca
      181 agcataatcc atcataaaat cagtataggt gaaaagatga actttcatct gcatatcaag
      241 taattggtat gaggcatttt ttgaggtgta ggatatgaag ttggattacc ttatagaaga
      301 ggaagataga gaaaaactgc tgctagctag atatttagaa tttgagaaaa agaattatgt
      361 agtgctgcct aagttatatg aaacattagg tttgtctaaa tttaaaacaa gaaattatat
      421 catagaatta aataaagaat ttactgaatt caaaacaaag ccagagatcc aaatttcaga
      481 agaagcagag atccatgtcg aacgtctgaa tttgacggat atcaaaaatt taagaagaat
      541 ctactttcaa cgatcaaaaa ttgctcgact gttaacggag atcgtggatt caaaagtaac
      601 gatcgaaaaa tttgcagaga atcatttttt aagcatatca agagcctatg taaaaagaag
      661 agaattagtc tcttttcttg aacagcatca aataaagtta aagaaaaaca tattagttgg
      721 ggaagaaata aacatacgga acgtattatt tggggtatat ttcggggtct ttaatggttt
      781 ttctatgcca tttagagaaa gcgtcatgaa tgaagcaaag agtatcgtgc aatattttga
      841 atatctgttc aatttaaaac tgtctgcaac aaaacgaatc aaattcaatt tgctaaccac
      901 tattagtttg ttgagggcct atgggaatca accaatcgga aaacgtttct tttcagatga
      961 atactttaag agctcagaag gaatgaagat catcaaggat ttatcacata tttcttttct
     1021 tcatatccct aaagagcaga tcattgatga gatttcttat atcatgttgt ttttgatcac
     1081 ggaagaagaa tttgaattag atggcgcatt tggacttgcg gaagctcatt ttcatgatat
     1141 ccacatgatt agtcaaaaaa tgtcagtgga attgattgat caattaccat tttcgattga
     1201 aatctctgaa gaagaaagac tatatatacg aaaagaactt cgtatgggta tgatgcatgt
     1261 caatcgaaaa aattggatat tcgactttga gatgactagc tttacgtcta aaaagcagct
     1321 acagtttttc ttcgagacgt atccaatatt cagtacagca atccaaaagg tcatacaaga
     1381 gaataaacgc tatttcttgg gaaaagatga acgtttcatg attcgcttat tttatgatta
     1441 tctcttttta ttggtcggta tttgtccggt atcatatttt gaagcaccga ttcatgtctg
     1501 tattgatttt tcgcaaggat ctgcttatac cgattacatt atttctcaag tgaaaggatt
     1561 taaaaattac aatattgtga ttgagagtcg aatcacttct cgtacgaata tttatttatc
     1621 tgattgttta cttgaaaaat ttaataaaga acagataatt tggaaaaatc caccgactcc
     1681 agatgactgg gaatattttg gaaataccat catcagagaa aaaaatagac atttaactga
     1741 aaaaatcagc tagtatttat ggatggcagc tttgtctcac atatttatta gctgatttat
     1801 gtttttttca aagaaaaggt a
//
LOCUS       DAFLWQ010000198         1762 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.206, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000198 DAFLWQ010000000
VERSION     DAFLWQ010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1762
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.206"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            514..1644
                     /locus_tag="L1V16_003061"
     CDS             514..1644
                     /locus_tag="L1V16_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBN1277321.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
BASE COUNT          522 a          284 c          360 g          596 t
ORIGIN      
        1 tataaaaaaa cacataaaac taaaaaatta tcaaagaatc ctggtgcaac tgaaagaatt
       61 tgcaacggga ttctttcaac ttatttgtta tttttttcta aaaaatatta aagattgtta
      121 aatttcacta tttcatttca aattccattg cctaatcatt aggaaaagtc tatcatgaac
      181 tcgtaaatag aatatagtaa taaccttgtt aggtgaggct cctatacaaa cataggctgt
      241 tgcccagaaa cgtcgaaagt cgccaatggg taaaacagaa actgttggat taaggctttt
      301 tccaatagct aagaatgttt tctttacgtt gtatagtgct aaaactcgga cgatgagatg
      361 atgctaggtc agaattcttg ttcgaaaagg tttctgacct tttctttata tttttgtgac
      421 tgacttattt gatgagacaa actcgctcct cacctgacaa gtggattgct gtgtgaggag
      481 gagatgcggt gaaaaaagat cgattggtgg attttgggtc cttatttgac tttgtccatg
      541 atcggtcttt tagaagtata cagtgccagt tcttatcgtt tattgcaagc cgatgaaaat
      601 acaaaaagtc tattattgcg tcaactaatt ttcatatttt tgagttggag cgtgatcttc
      661 ttagctcgtt cagtcaaact acactattta cttcacccta aaatagcagg atacggttta
      721 gccttatcga ttttcttttt agtattagta agaataggga tattcggtgt cactgtcaac
      781 ggcgcacaac gttggatctc tctgtttggc attcaattcc agccttctga actggcaaat
      841 ctttttttga ttttttattt aagctggttt tttcgtgacg gaaatagtag cccaaaagat
      901 ctaaaaaaac cattcctgat tacagtaggt ataacttttc tgattttatt tcagccaaag
      961 attgctggag cattgatgat cctttcgatt gcgtgggtca tattttgggc agcggcggtt
     1021 ccatttaaaa aagggatcta tctaatcgtt actttttctg cattgctgat tggagcagca
     1081 ggcggggtat tatatttagg aaataaaggt tggcttccac agatgtttaa tcatgcttat
     1141 gaaaggatcg cgactttaag agattctttt atcgatagtc atggtgcggg ctatcaaatg
     1201 acccattcgt tttatgcact atataatggt ggcatatttg ggcggggatt aggaaatagt
     1261 atcacaaaaa aagggtatct tccagagaca gaaacagatt ttattttttc gattattaca
     1321 gaagagcttg ggctaatcgg tgcattgtgt gtgcttttct tattgttctc attatgcatg
     1381 agaatctttt gtttaagcag tcgctgtaaa aatcagcaag ctggattgtt tcttttagga
     1441 ttcggaactt tgctattcgt tcagacgata atgaacgtgg gaagtatcgc ggggctgatg
     1501 ccaatgactg gtgtgccatt gccatttgtt agctacggag gaacaagtta tctgatcctt
     1561 tctttaggaa tcggaatcac gttgaatatt tcttcaaaga tacaggccga agagttggcg
     1621 ctctatcgac ctgaaaaaca ataaagagaa actgagaaac tctcagtttg aattatcata
     1681 aagtacaatc ttttattttt caagcgagag gttcttttag aaagaggaat tcgcaatgaa
     1741 agtatctcaa aaaatcatat ta
//
LOCUS       DAFLWQ010000199         1738 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.207, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000199 DAFLWQ010000000
VERSION     DAFLWQ010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.207"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            226..1026
                     /gene="aph(2'')-I"
                     /locus_tag="L1V16_003062"
                     /pseudo
     CDS             226..1026
                     /gene="aph(2'')-I"
                     /locus_tag="L1V16_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021424053.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="APH(2'')-Ia/If/Ih family aminoglycoside
                     O-phosphotransferase"
     gene            1010..1402
                     /locus_tag="L1V16_003063"
     CDS             1010..1402
                     /locus_tag="L1V16_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1277322.1"
                     /translation="MKLLFIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            1403..>1738
                     /locus_tag="L1V16_003064"
     CDS             1403..>1738
                     /locus_tag="L1V16_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1277323.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGI"
BASE COUNT          717 a          133 c          296 g          592 t
ORIGIN      
        1 acaagatata ttaaattgat ttttgaattt ttgaaaaaag aaagaaatgc taatgcagtt
       61 attttagacc ctcataaaaa taatccaaga gcaataaggg cataccaaaa atctggtttt
      121 agaattattg aagatttgcc agaacatgaa ttacacgagg gcaaaaaaga agattgttat
      181 ttaatggaat atagatatga tgataatgcc acaaatgtta aggcaatgaa atatttaatt
      241 gagcattact ttgataattt caaagtagat agtattgaaa taatcggtag tggttatgat
      301 agtgtggcat atttagttaa taatgaatac atttttaaaa caaaatttag tactaataag
      361 aaaaaaggtt atgcaaaaga aaaagcaata tataattttt taaatacaaa tttagaaact
      421 aatgtaaaaa ttcctaatat tgaatattcg tatattagtg atgaattatc tatactaggt
      481 tataaagaaa ttaaaggaac ttttttaaca ccagaaattt attctactat gtcagaagaa
      541 gaacaaaatt tgttaaaacg agatattgcc agttttttaa gacaaatgca cggtttagat
      601 tatacagata ttagtgaatg tactattgat aataaacaaa atgtattaga agagtatata
      661 ttgttgcgtg aaactattta taatgattta actgatatag aaaaagatta tatagaaagt
      721 tttatggaaa gactaaatgc aacaacagtt tttgagggta aaaagtgttt atgccataat
      781 gattttagtt gtaatcatct attgttagat ggcaataata gattaactgg aataattgat
      841 tttggagatt ctggaattat agatgaatat tgtgatttta tatacttact tgaagatagt
      901 gaagaagaaa taggaacaaa ttttggagaa gatatattaa gaatgtatgg aaatatagat
      961 attgagaaag caaaagaata tcaagatata gttgaagaat attatcctat tgaaactatt
     1021 gtttattgat gataatatgg tttttgatat tgataattta aaaggatttc ttaatgatac
     1081 cagttcattt gggtttatag ctaaagaaaa taataaaatt ataggatttg catattgcta
     1141 tacactttta agacctgatg gaaaaacaat gttttattta cactcaatag gaatgttacc
     1201 taactatcaa gacaaaggtt atggttcaaa attattatct tttattaagg aatattctaa
     1261 agagattggt tgttctgaaa tgtttttaat aactgataaa ggtaatccta gagcttgcca
     1321 tgtatatgaa aaattaggtg gtaaaaatga ttataaagat gaaatagtat atgtatatga
     1381 ttatgaaaaa ggtgataaat aaatgaatat agttgaaaat gaaatatgta taagaacttt
     1441 aatagatgat gattttcctt tgatgttaaa atggttaact gatgaaagag tattagaatt
     1501 ttatgatggt agagataaaa aatatacatt agaatcatta aaaaaacatt atacagagcc
     1561 ttgggaagat gaagttttta gagtaattat tgaatataac aatgttccta ttggatatgg
     1621 acaaatatat aaaatgtatg atgagttata tactgattat cattatccaa aaactgatga
     1681 gatagtctat ggtatggatc aatttatagg agagccaaat tattggagta aaggaatt
//
LOCUS       DAFLWQ010000200         1713 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.208, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000200 DAFLWQ010000000
VERSION     DAFLWQ010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1713
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.208"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..531
                     /locus_tag="L1V16_003065"
     CDS             <1..531
                     /locus_tag="L1V16_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277324.1"
                     /translation="DENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYGIDETDI
                     FAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTLLISPIS
                     TISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLSEEKILL
                     PENWAELRKLVEYGII"
     gene            518..>1713
                     /locus_tag="L1V16_003066"
     CDS             518..>1713
                     /locus_tag="L1V16_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBN1277325.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLL"
BASE COUNT          557 a          223 c          277 g          656 t
ORIGIN      
        1 gatgaaaaca gtaaattgat gaaaaacata caatcaatct ttgggataga agaagttttt
       61 gtcggagata aatgtatctt ttttgatcaa cctttattat ctgatggtta tggcatagat
      121 gaaacagata ttttcgctaa agtaaatagt atattttctg gaaaaaaaga aactttaatt
      181 aagcttcatc ctagagcaag gacaaatcgt tatggtgaaa aaaacatatt gaattccagt
      241 ttaccgtttg aagtcttgct acttgaaaat gacttctctt caacactttt gattagtcct
      301 atatctacaa tttctttttc accatctatg atgtttgaaa agacgatcaa ctctattatg
      361 ttggctaaat taattttaaa tgaatataca gcattatctg aagataaaaa agaaacattg
      421 acaaatattg ttcttttctg tgaacattat aaccgtctat cagaagaaaa aattttactc
      481 ccagaaaact gggcagaatt aagaaagttg gtagagtatg ggattattta acacactttc
      541 caagtcaaaa ttagttaagt ccagtttctg gtatactata gggaattttt ttattaaggg
      601 aatttcattc ataactattc ctatttttgt aaatattact actcaagcag aatatggttt
      661 gattaataat ttcacttcat ttgtatcaat tttttcgatt cttgttgggc taagcctaaa
      721 ttcggcaatt aataatgcaa gttttgacta taaagatgac ataaatgaat ttatgtcatc
      781 ggtactttct ctagctacac tttcgttaat tgtgttctta ttaataggga acatatattt
      841 tttgttttca aatgcttttt ttgatatgaa ccaacttgta tttaatttga tgttattaca
      901 aagttttgct agttttgtaa ttagttatat ccagtcttat tttacgatta actttaacca
      961 ttttaaatat ttgattttat cttttatatc tacttttttg aatattgcaa tctctgtagc
     1021 tttgatgcag acattatatt ttgatgataa atatgttggc agagtagtcg gcggaacact
     1081 gtcatttgtg ttgataggtt tagtaattta tttaagaata atgataaagg gtgctcattt
     1141 ttttgataaa aaacagtgga gatacgcttt aaaaatctct ttgccgctaa tcccacattc
     1201 cttagcaaat atagttttag cacaattcga tagaattatg attaattctt atttaggtcc
     1261 tgctgcgggg ggaatatatt cctacattag taacataggt attattctaa gcgtaatatg
     1321 gatgtctact aataacgcct gggttccatg gttctatggt gagatgagta aaaataatga
     1381 aaaaaaagtg aagaaagtta gtaactatta tttagtagtc tttactttga ttacgatgat
     1441 tgtaatggta gtttcgattg atttagcaaa atttatggct ccgaaagact attattctgg
     1501 gttatcttta gtggttccga taaccttagg ctatttcttt cagtttttat atagtttacc
     1561 agttaatgct gaattttatg agaaaaaaac atcgtttatt gcgattggta cagtagcaag
     1621 tgctatagtt aatatactat taaacatgat tttcatacct aggttaggaa taattgctgc
     1681 tggatacaca accgtattta cgtatttttt act
//
LOCUS       DAFLWQ010000201         1640 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.209, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000201 DAFLWQ010000000
VERSION     DAFLWQ010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.209"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            416..>1640
                     /gene="ltrA"
                     /locus_tag="L1V16_003067"
     CDS             416..>1640
                     /gene="ltrA"
                     /locus_tag="L1V16_003067"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBN1277326.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRL"
BASE COUNT          586 a          299 c          388 g          367 t
ORIGIN      
        1 aacttggtgg tgaaagtcca ctacaggctt ggcagtagga actgttagcg aaagacaagg
       61 cggcaatcgt gaggttgtgg ctgaaggaag tcggacgcaa actcctgaac tgacgaacag
      121 aaactagata caaggctgaa ttaggtcgga taagtcttca tcacaagaca aagtccaata
      181 ctgcccgaaa cctatacagt aaatctagca gttacatggg aggaaagttt tcactcttac
      241 cgggggagat ctcatgaggg tgttgtgggc gttgaatgaa aacaaaccag cacaacgatc
      301 atggcgacat gatggtgaat catgagaagt cagccgaggt catagtagta acgacactga
      361 ccgttacgaa ggactgaaca ataagaatct tgaataattt aggaggtgtg agaagatgcg
      421 acgaccgcag aaaacaagaa aacttggcta tcatcaaaga gctagtgtgg aacacgaagg
      481 gtatgatgaa gtgcgcagca cttcttgcgg tgaacagagg aaacaagatg gtgtagaaaa
      541 tctgtttggg agaattctag atcggaataa tctcaatcaa gcgtatcttc aagtagtcag
      601 aaataaaggg gcggctggtg cagatgggat gaccgtcgat caactgcttc cttacttgaa
      661 agagcaccgc gaggaattac tatccaattt acgccaaggg aactataaac ctcagcctgt
      721 tttgcgagta gaaataccga aaccaaacgg cggtgtaaga aaactaggaa ttcccacggt
      781 tattgatcgt atgcttcaac aggcaatcaa tcaagtgtta caaccgctat ttgaaccaga
      841 attctcagat aatagttatg ggtttcgccc aaatcgcagc gcacatgacg cagtgaagaa
      901 agcaaaatct tattatgaac aaggttaccg atatgtggtg gacattgata tgaaagccta
      961 ctttgacacc gtaaatcacg ataagctgat gtatttcatt gagcggaaag taaaggacaa
     1021 acaagtccta aaactgatcc gtcaatactt aatgagtggt gtaatggaaa atggactcat
     1081 cacaacaact gaagaaggaa cgccccaagg aggcaatctc tctcccctgt taagtaacat
     1141 ctacctgaac gaatttgatc aagtgctaga aaatctagga cataaatttg ttcgatacgc
     1201 cgatgactgc aatatctatg ttagaagcaa acgagcagga cagcgtgtga tgaagaaatc
     1261 cattcaattt ctcgaagaac aactaaagtt gacggtaaat cgagaaaaga gtgcggtagg
     1321 aagtccattg aaacgaaagt ttcttggatt ctgcattctg ccaacaaaga aaggtattaa
     1381 aattcgccct cacgcaaaag caaaacagcg tgtgaaaagc aagctcaaac aactcactaa
     1441 aagaaaccgt ggaagaagta tccaacttat tttaaaagaa atcaagcaac taatgactgg
     1501 ttggatcaac tactatggaa ttggtgagat gaaagaattc atgagggagt taaacggttg
     1561 gttgaagcga agaatcagac aatatatttg gaaacaatgg aagaatccaa gaaccaaaag
     1621 aaaaaatctg attcgtttag
//
LOCUS       DAFLWQ010000202         1604 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.210, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000202 DAFLWQ010000000
VERSION     DAFLWQ010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.210"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            635..>1604
                     /locus_tag="L1V16_003068"
     CDS             635..>1604
                     /locus_tag="L1V16_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBN1277327.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVDDK
                     VHPLKLSWSIDRITIVGKLNDTIAYWTQNGVVFVDFEQLMRLNENQGYLKSVGTNGWQ
                     LFDQYGEDIAYIEMLKFHPDKGRIDFNPNKIGEFLKGSMKQFIHDLFLDAHFSRADIA
                     CDILGVPDDFITQYRIVDPVSFKPIYGRSGKLETAYWGSRASERQVRMYNKKLEQERK
                     KQIVPKEIETWWRIEMQLRRGKATDWHAMVRESLDSFASPHYLPGDVKPVDRIMIKGL
                     NQDHSEWAYISRNLKYRLRKLLKEESQNDELTNHLRETFKESANDLK"
BASE COUNT          540 a          251 c          364 g          449 t
ORIGIN      
        1 aatacaagca tttctcataa taatcgtgag ttaactgata gccaaaaaat caatggtttg
       61 tctggtagaa aataattagc agatttacaa gtgggaaata aaaagctgaa agaagaaaat
      121 tgcatttcaa actacatttt ctacaatagc tctaaaatgg catattttgc gttctgagcg
      181 gttttagcgt ttatttcgtt tagttatcgg cacaatcgtt aaaacacgtt agaggagcga
      241 aaatggagcc tgtaaggcga ctggtagcgg aacgatcgtg ttagattgtg aaaaccgata
      301 gctgaatgaa ataaacagcg ggtgcgccct ttccatttcg gcaggaggag gctcaagggg
      361 ttcggggaat gaaattccct gaggtctttt tattttttta ggaggagtgc tataatcaaa
      421 gaaaacgaga aaaaagagca aaataaaagc cgagcagtgc gctaacactc tcgactattt
      481 acggaaacta cttcacctag ctccgtaact caggttcatt atacgaatat ttttaggttt
      541 cttcaagcta gagatttttg gatatgaatt tttagggtta cgtgaactct ggaaattctt
      601 tccaaaagtc tcttttttcg tctggaggac gaaaatggca aatgaaaatc agttgagtga
      661 aattcaatca aaaattgaag gtcgaggggc agaaaaaaga acaacgataa atcagctcga
      721 aaaacttaac cgtatttcta acaggcggtt aagtgttgac gataaggtac accccctaaa
      781 attaagttgg tcaatcgatc gaattacaat cgtcggaaaa ctgaatgata ccatagctta
      841 ttggacgcaa aatggagttg tgtttgtcga ttttgagcaa ttaatgcgtt tgaatgaaaa
      901 tcaagggtat ttgaagtcgg ttggtacaaa tggttggcaa ttatttgacc aatatggaga
      961 agatatcgcc tatatcgaaa tgttaaaatt tcaccctgac aaaggtcgta ttgattttaa
     1021 tccaaataaa attggcgagt ttttaaaggg gtcgatgaaa caattcattc atgatttgtt
     1081 tctggatgcg catttctcac gtgcagatat tgcttgcgat attctcggtg ttcctgatga
     1141 ttttattacc cagtatcgaa tcgttgaccc tgtgtctttt aagccaattt atggccgttc
     1201 tggcaaatta gaaacagcgt actggggtag tcgtgccagc gagcgacaag tgcggatgta
     1261 caacaaaaag cttgaacagg aacgaaaaaa acagattgta ccaaaagaaa tcgaaacatg
     1321 gtggcgtata gaaatgcagc taagacgtgg caaagcaaca gattggcatg cgatggttcg
     1381 ggaaagttta gatagctttg caagtcctca ttacttgcct ggagatgtaa aacctgttga
     1441 tagaattatg ataaaagggc tgaatcaaga tcattcagag tgggcgtata ttagcagaaa
     1501 tttgaaatat agattgcgca aattgttgaa agaagaaagc caaaacgatg agttgacgaa
     1561 tcatttacga gagacgttta aggaatctgc aaacgacttg aaaa
//
LOCUS       DAFLWQ010000203         1586 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.211, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000203 DAFLWQ010000000
VERSION     DAFLWQ010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.211"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            73..1539
                     /locus_tag="L1V16_003069"
     CDS             73..1539
                     /locus_tag="L1V16_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBN1277328.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          439 a          291 c          333 g          523 t
ORIGIN      
        1 agttttttag ttaaattttt cggtaaagat gtataatatt ttctgaaaat ttaaagaatt
       61 ggggtataga ttatggaaaa acagcaagac aagggcttct tcgggcagcc gaagggattg
      121 tcaactttgt tcttcactga gatgtgggaa cgatttagtt attacggtat gcgtgcatta
      181 cttatctatt atatgtacga tacagttgcc aacgggggac ttggattacc acgagcaaca
      241 gcattagcta tcatgtcgat ctacggatct ttgatctaca tgtctagtat cgtcggcgga
      301 tgggtatctg accgagtgtt aggagcaaaa cgcactgtat tcttcggtgg agttttcatt
      361 atgcttggcc acatcgtctt ggctttacca tttggtgtaa gtacattgtt tgtttcgatg
      421 gcattgatta ttatcggaac cgcctttttg aaaccaaatg tttctggcat ggtcggacat
      481 ctttattcaa agactgactt gcgaagagat gcaggatttt cgatttttta catgggtgtc
      541 aacttagggg cattattagc accactaatc gttggtacaa tcggtcaaga atataactat
      601 catttagggt tctctttagc tgctattggg atgttctttg gattattaca atacatcatc
      661 caaggacgca agacattaga cggagtgggt acaacaccgc cgaatccttt gacaactgaa
      721 gaacgtaaag gattcatccg taacttgatc atcgcacttg ttgttatcgc tgcagtattc
      781 ggcggggcac aactaactgg tcatctgaca attgactttt ttgtcaatac aatcagtgta
      841 ttggggatta tcttaccgtt gtattacttt atcaaaatgc tgacttcaaa agatgtaact
      901 gctgaagaaa aaccaagagt atgggcttat atcccattat tccttgcagc aatcattttc
      961 tggtcattac aagaacaagg ttcatctatc ttagctttat ttgctagtga acgtacacaa
     1021 tctacgctat ttggtgtaac gatccaagca agctggtatc aatcattgaa tccaattttc
     1081 atctttattc tgacaccagt attcgtaacg atgtggacga aacttggtga acgtcaacca
     1141 tctacagtag tgaaattctc tcttggactt ttatttgcag gattatcgta cttgctattg
     1201 atgttgccgg gtatgcttta tggtacaagt ggaaaagtaa gtccattgtg gttgttggga
     1261 agtttcttca tcgtggttat tgctgaattg tgtctttcac cagttggttt gtctgtgaca
     1321 acaaaattag caccacgagc atttgaatca caaacaatcg ctatttggtt cttagctgat
     1381 gcttcttcac aagcaatcaa tgcacaaatt gcacgcttct acacaccggg aacagaatct
     1441 gcttacttcg gtattatcgg tgcagtagca atcgtcggtg gtatcttgct atttactgtg
     1501 aaagaaccaa tcaaaaaact aatgggctct attcattaat caatgaacat aaaaacagga
     1561 attgcttatt tgcagcagtt cctgtt
//
LOCUS       DAFLWQ010000204         1573 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.212, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000204 DAFLWQ010000000
VERSION     DAFLWQ010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.212"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
BASE COUNT          594 a          179 c          320 g          480 t
ORIGIN      
        1 attatcgaac acctttggaa gtatttttga gttacgtaag tattgatgat ctgtctaatt
       61 taatttgaca attaagaaag tattaacttg ttttgtgaaa aagagaattt gaaaaacgat
      121 tggcgaacaa atgctcggta ggtatggtat aaatacagag ctaattggtg tgatgaaatc
      181 agatattcgc gtgagattca gtaaagtagg agttcgaaaa cagctaggtg acaaacagta
      241 ttgctttggt acttcggaat ggtttatcaa attcttatca acagttcact tctctttatg
      301 tttgagtgat gattcgttag gttattgctt ggaaagaccg gatgagagta gaagagttta
      361 attttataaa gtgaaaagag gtaatgtacg atatacgtag ggctgaacca atagaggata
      421 agcaaacgat gttacaggcg caaaattcat agcttactgt tttggagata acagaagagg
      481 aaataatgca gaagtaaggc gaaaaaagga cggaagccta acagcatatg aaataaagaa
      541 aaatattata actactgata aatcggtatt gagcaaagta ctaataggag tcaaaaacat
      601 tcataagcta tgagtgtttc ttggctactt ttttattttt atgtatctac aaaagtttcc
      661 aggggcagaa cctgtgatta ttaatggaag aacctcaagt attgtcttaa atcattgtta
      721 tgaaaatgga ttaaaagagt tcatcaaggt gtgattaaca agttactttt cattacatcg
      781 aatttttcag aagttgctta tattggtgat gatattaatg atttatcatg tatgacatct
      841 gtgaagaagc gggaggaata gtagaatgtc caaaaaatgc cacaagaaat gagattgaat
      901 tatctgattt tattgtaact cacagtggtg gtgacgaatc tgtgatagag tttattgagt
      961 ggatattgga atcgatatag tgtagtagta cagaaaaatt atcatacaat taatactagg
     1021 cataagaata ttggcatatt ctagagttaa aagtaactat tcgaaaagga taaggttaga
     1081 attttttgtt ttgccagtgg aagaatataa aaagggcatt ggaaattaat atattagaat
     1141 gctaagcgga gaaaaaaata tatgaaaagt acgtccttgt gatgggatgg aaaaatacac
     1201 ttatttcaaa caacgataat ataattatgt gaaccgaagt atactcgctt ctaattcaat
     1261 cctcaaatcc cgacagtcgc gacttcaaaa aagcgtatag ttttaatgta tccccatatg
     1321 atccgaaaaa tggtaattta caattaacag tttgatgatg ttgaagatgt ggaaatgctg
     1381 aaattaccat gatgagaaac acattaatta aagggaatta attaactaga atataatctg
     1441 attcaatttg aattaagcaa aaaaaggctg agttttaaat aatcgcgaat tgtaaaatta
     1501 agttagaaaa ataaaaaggc atttatggta cactcaaatt gtatttccga cgaaagaaaa
     1561 caaaggagtg taa
//
LOCUS       DAFLWQ010000205         1553 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.213, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000205 DAFLWQ010000000
VERSION     DAFLWQ010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1553
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.213"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            635..>1553
                     /locus_tag="L1V16_003070"
     CDS             635..>1553
                     /locus_tag="L1V16_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBN1277329.1"
                     /translation="MSKKGIIVNEWEKLNRISNRRLNVQNLNTPLKLQWSIDRITIVG
                     KLKENIYYHTPNDVLILNFEQLMQLNEGNGFVKSVGKNGWQIVDQYEENIAYIELLQF
                     HEGKARIDFNPNKIGQFLASSMKNFIHDLFLEPHFSRADIACDMVNVPDEFIMQYRVV
                     DPVSFKPIYGRSGKLESAYWGSRASERQIRLYNKKLEQETKRKVVPKEVETWWRLEMQ
                     LRRGKATDWHNMVQESLNSFASLHFLPIDTTPTDRIMLAGLMSDQNFWSLLSRNSKYK
                     YRELLKEESQNDELTNHLRETFAESADNLK"
BASE COUNT          511 a          240 c          342 g          460 t
ORIGIN      
        1 aatacaagca tttctcataa taatcgtgag ttaactgata gccaaaaaat taatagtttg
       61 tctggtagaa aataattagc agatttacaa gtgggaaata aaaagctgaa agaagaaaat
      121 tgcatttcaa actacatttt ctacaataac tctaaaatgg catattttgc gttctgagcg
      181 gttttagcgt ttatttcgtt tagttatcgg cacaatcggt gaaacacgtt agaggagcga
      241 aaatggagcc tgtaaggcga ctggtagcgg aacggtcgtg ttagattgtg tagccgatag
      301 ctgaacgaaa taaatgctgg cagcgccatt ctatttcggc aggaggaggc tcaaggggtt
      361 cggggaatga aattccctga ggtcttttta ttttttctag aggagtgcta taatcaaaga
      421 aaatgagaaa aaagagtaaa aaaatagtcg agcagtgttg acgcactctc gacctttacg
      481 gaaactactt cacctagttc cgtaactcaa gttcattata cgaatatttt taggtttctt
      541 caagctagag atttttggat gtggattttt agagttacgt gaactctgga aattctttcc
      601 aagaatctct tttttcgttg aggaggagct atttttgagt aaaaaaggca taatcgtaaa
      661 tgagtgggaa aaacttaacc gtatttctaa caggcggtta aatgttcaaa atttgaacac
      721 ccccctaaaa ttacagtggt caatcgaccg aattaccatt gttggaaaat tgaaagaaaa
      781 tatttattat cacacaccaa atgatgtctt gattttaaat tttgagcaat tgatgcaatt
      841 gaatgagggg aatgggtttg tcaaatcagt tggtaaaaat ggctggcaaa ttgtcgacca
      901 atacgaagaa aatatcgcgt atattgagct cttgcaattt catgaaggga aagcacgaat
      961 tgattttaat cccaataaaa ttggtcagtt tttagccagt tcgatgaaaa atttcattca
     1021 tgatttgttt ttagaacccc atttttcgcg ggcagatatc gcttgcgata tggttaatgt
     1081 tccggatgag tttattatgc aatatcgtgt ggttgacccg gtatcgttca aaccgattta
     1141 cgggcgttct ggaaaactag aatcagctta ttggggtagc cgtgccagcg aacgacaaat
     1201 tcggctatac aataaaaaat tggaacaaga aaccaaacga aaagttgtac caaaggaagt
     1261 tgagacttgg tggcggttag aaatgcaact acggcgtggc aaggcaaccg attggcataa
     1321 tatggttcaa gaaagtttga atagttttgc gagcctgcat tttttgccga ttgatacaac
     1381 acctacagat agaataatgc tcgctggttt aatgtctgat caaaatttct ggtctctttt
     1441 gtcgaggaat tcaaaatata aatatcggga attgctgaaa gaagaaagtc aaaatgatga
     1501 attgacgaat catttgcgag aaacgtttgc agaatcggca gacaatttga aac
//
LOCUS       DAFLWQ010000206         1469 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.214, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000206 DAFLWQ010000000
VERSION     DAFLWQ010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1469
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.214"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(441..1055)
                     /locus_tag="L1V16_003071"
     CDS             complement(441..1055)
                     /locus_tag="L1V16_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1277330.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
BASE COUNT          475 a          278 c          244 g          472 t
ORIGIN      
        1 tttttgtgta ttttatttct attagaaaaa ggtatcctgt tggacaattt tgttatatca
       61 ggtaaacttc attgcaataa tgataacaaa tgtactataa ttactttgta aagagttttg
      121 gggaagactc tttcatcaac gtgtattaag agacaagaaa gaatccatat ggattctttc
      181 ttgtctcttt ttccactact ttttattttt ctgacactac atattcttat aactcatttc
      241 tcataactgt gaaacaactt ataaaaataa caaactttaa acaaaacaag cttaaaatca
      301 aagatgatcc atcttaaaat aactaaaaca aaaaaagtag tcgttgttaa tcctcattaa
      361 taatcgtttt ctttttttca aacgctccat ttttatgtgg aacattattt ttttaaggaa
      421 ctttgtcaac atgtggataa ctattttcca cttgtgtcct ggactagctg ttttgctgta
      481 aaatacaaaa cttgctgcag caaaaagatc gttgcaagag aggctgttcc gcagatcgct
      541 ggatctagat ttggcaaagt caagactgca tcatgtaaat tggcgtggtt gtccaaaacc
      601 aaatcagcaa attcaaataa tcgcaaacca ctgctatgtt gcgatttgat acttcgtgac
      661 aaatcaaatc cagtaacaat gattaatgga tgaccatttt ctttgatcca ctgagctagt
      721 tcgatgattg ccgggtttct tccttcattc gaaagaagaa gaaaaatgtc ttctgatttg
      781 acagaaagct gatcaataat tgcctgtcct gcaccttcta gcgtttcata gacacctccg
      841 gctggatttt caatcaatat acttggtaca agatccgggg tttgatccca aaattcaaat
      901 gctacaccac ttagtgtgcg gctagcatat atctgcaatc taccaccttg attaatttgt
      961 ttcgcgatcc aagtgccagc ttgaagcatc agcggctctt ctatccttaa tttctcttcc
     1021 aattggtgat aatagtcaaa ataacataaa ctcatttatc tctcccgcct agctatactt
     1081 gacatgaata gaaacagctg cctaatctaa ggaagtacat aaaaaaacag tagttagaca
     1141 gtaacacatg tggtctttgc tgtttcaaac acaaaaaagg cattgaacga atacgcccaa
     1201 taccttgaca tagcaaataa aacaacgtgc agaccatgga aaatatctac ataggggtag
     1261 aattttcacc ctagattagg tacaataaat taggtcgatg cactgcattg actatggcaa
     1321 aatgatcggt cagggtgtat gtgtgtgact ggtcattccc tgattcttag cgccaactaa
     1381 gggtcaggga gccttttttt attcagctgt ttctatctga atttattgta agtaatctct
     1441 tatccaagtg caagcaagaa aatacaaaa
//
LOCUS       DAFLWQ010000207         1456 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.215, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000207 DAFLWQ010000000
VERSION     DAFLWQ010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.215"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            76..1416
                     /locus_tag="L1V16_003072"
     CDS             76..1416
                     /locus_tag="L1V16_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBN1277331.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
BASE COUNT          462 a          322 c          284 g          388 t
ORIGIN      
        1 ctaataaacg caaacagaca ccttgaaatc ctttagaata aagtcgacga aaaccattca
       61 aaggagtgtt tcaagatgtc ctattcagag tttaccaaag agttactaga tattctagac
      121 ctaaatctta cctttcatga agatgccttt cgcaaagagc gcattaatga cgaaacatgt
      181 tttgtttttg atggcacatt gacctatcaa ccagaggaat gcttccattg ccactatcaa
      241 aataagcaaa cgatcattaa atggggctgg aaaaaagtat ccatcttatt gaatgatgtc
      301 agtaactaca agaccattgt gcggattaac aaacagcgct tcaaatgtaa acactgtgga
      361 aagacttttt tagcagaaga ttcagttagc gatcgtcgct gctccattgc ccgcagagtc
      421 aaacaagcca ttcttgagct attaagtgag cctatttcta tgtctttgat tgcacgtatg
      481 aagcacattt ctccgaccac tgtcattcga atacttcgca gccttcggcc taaaaccgtt
      541 tctttgaacc agccgttacc agaagtggtg tgtttcgatg aattcaaatc ggtgaaaaac
      601 gtctcgggag ccatgagctt tgtcatgatg gacggcaaga cccatcaact gattgatatt
      661 gtggaaaatc ggcaactcaa tcctttacgc gactatttct tgcgctaccc tagaaaagtc
      721 cgtgaacaag tacgtctagt ggtttcagat ttctatacac cctatcgcac attggtgaaa
      781 gagtgttttc cgaatgcccg aatcgtcgcc gatcgctttc atattagcca acacatcggt
      841 cgggccttta ccaaccaccg aattcaagta atgaagacct ttaaaaaagg ggatcgtcgg
      901 tcgaagcact taaagaaata ctggagacta cttcaaaaga atgcgtggga attgaatggt
      961 cagcatcgct actggcgtcc gtcatttcga gatcatctga cagaagcgga gatagtcgat
     1021 cggctattat attatgatga ctccttaaag cgaggctacg aagtctacca ggtttttctt
     1081 tccgctatca gaagacaaga tgttcctgaa ttcgtcgcgc tcctaaaaga agactacaag
     1141 gagttgccag agcactatca accagtgttc acgaccttca agaaatatcg aacagaaatc
     1201 aaacgagcgt tgcgagttcc ctattccaac ggccctatag aatgtttgaa caaccatatc
     1261 aaagtactaa aacgaattgc ctatggcttt agaaactttc aaaactaccg agaacgaatc
     1321 tttttatatc gaggaaaata tttcaagaaa actaagaaca ctacccaact gactaaagcc
     1381 agaacaacaa cacggctaga caagatagct gtctagccgt gtgagtatct cgattattct
     1441 attgaatttc ttcacc
//
LOCUS       DAFLWQ010000208         1456 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.216, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000208 DAFLWQ010000000
VERSION     DAFLWQ010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.216"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            155..>1456
                     /locus_tag="L1V16_003073"
     CDS             155..>1456
                     /locus_tag="L1V16_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HBN1277332.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRR"
BASE COUNT          461 a          297 c          269 g          429 t
ORIGIN      
        1 ctgaataatt catactttta attaaaacca tgtgaaactg cctcacggca gcttacaatt
       61 actttttcat cttcacccgt taagtgatga aaaaagaacc cctttctgct atggttaaag
      121 tgactaaacc aaccaaaaga aaggagttct tttcatgact agcttacaca aaaaccaagt
      181 aaaattcaat tcaaatatca ctatttctca tacaggtggt caattatcga gtgattcggg
      241 tctcgtccta gtgaaagagc tgatgaacat ctttggtttt tctgaactgg ctaagcaaca
      301 cattcacatt gaagacgaac gagcgtattt tactcatgac aacttatcca tacttgagca
      361 gttcattatg caattaattg ctggttactc agctgattct gcagctaatc tcctgagaca
      421 agatcctgtg tttaaagctg ttttagatag gaaagaactc gcttctcaat cttcactttc
      481 ccgattttta gatcgactat ctgaggagaa tatccatgaa cttcaagctt tgaaccaaga
      541 acttatcgat aaagcacgcc tcatccgtaa tgatacggaa ttaatcattg atttagattc
      601 gacccattca gatacatttg gtcaccaaga acaaacgaat tataatacac actaccaaac
      661 ctatggttac catccattgg tagcttttga cggattgact ggtgacttct taaaagctga
      721 actacgttca ggaaatcaat atacatcaaa aggcgtaaag gagtttctca cacctttatt
      781 agagcactat aatcactctc taccaaacac tgacatcttg gttcgtggag acagcgggtt
      841 cgctacacct ggtgtgtatg attcgtgtga atcaaaaaag agtcattatg ttattcgact
      901 gaagaataat cgtagactag gtcaaatagc tgagaaatca gtactttatg gcgataatca
      961 aaagtgggaa gaacgagaag ttcagtactt ctcgaccact tatcaagcac aatcctggtc
     1021 acaaagtcgt cgcgtgtgta tacgctcaac acgtgaagcg ggcgaactac tctttcgaca
     1081 tgaatttatc gtgacgaatc tatcagaaaa tgtttctcct gataccatct tttctatcta
     1141 tgccaaacgt ggcacaatgg agaacttcat taaagaagcg aaagctggct tttactttga
     1201 caaaacagac agtcctcgct ttttggagaa tcatgtccga atgatgctca gcttgatagc
     1261 ttacaactta gtcaacttct taagaacgat tggctttgaa gaagtccaaa agggaatgac
     1321 cattcattct attcgattga agtttctgaa agttgctggg aaattagtcc aaacgggtag
     1381 acgagtctat ctcaaattat ctagttatca tgtgtatcag aatgaattct acagggtctt
     1441 tgctcgcctg aggcga
//
LOCUS       DAFLWQ010000209         1455 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.217, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000209 DAFLWQ010000000
VERSION     DAFLWQ010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1455
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.217"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            273..1442
                     /locus_tag="L1V16_003074"
     CDS             273..1442
                     /locus_tag="L1V16_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBN1277333.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
BASE COUNT          533 a          204 c          239 g          479 t
ORIGIN      
        1 gttggtagta taatttaaag gtaataagtt attcttttat tactatgttt gggttttata
       61 gcaaagaaag tttaataaga gtttggacct agcaaacaat attaatgagg tcattaaatc
      121 ttattatctt tagtgatata acgaaatatc tacacagaca aaatgatagc gtaaaatatt
      181 ttgtgtaaat agatatttag ggtagaaaaa aagaaagtcc attctgtaaa attaaagtta
      241 ccacaaccga aattttatag gaggactttc tcatgcccaa ttttactaca gaaattatgg
      301 aaacactaat caataaaggt gatttagatg aattatttcg atgtcattta gaattagctg
      361 ttaattcatt attgcaggct gaattaacag cttttcttga ttatgaaaaa tatgatcgtg
      421 ctgggttcaa ttcaggtaat tcccgtaatg ggaattattc acgttcattc agaacagagt
      481 atggagaatt aaatttggta attcctagag atagaaatgg taagttttct caacaaactt
      541 tacctgctta taaaagaacc aatgactctt tagaaaccac tattattcag ctatttcaaa
      601 aaggaattac tatgtctgaa atctctgaat tgattgaaaa aatgtacggg catcactata
      661 cgccacaaac catttcaaat atgactaaaa tagtttctga agatattatt gcctttaaag
      721 aaaggtcctt agaatccaga tactctgtca tttttatgga tgctactcac attcctttaa
      781 aaagacaaac tgtttcaaaa gaagcagttt atattgtaat tggcattcga ttagatggaa
      841 ccaaagaggt tcttgggttt agtcttgctc caactgaatc tgcttatgtt tggaaagaga
      901 ttcttcaaga cctaaaagac cgtggtttaa aagaggtttt attagtcgta actgatggtt
      961 taagtggcat taacgatagt attcatagtg tttatccaaa tgctcaattt caacaatgtt
     1021 gtgtccatat atctagaaat atcgctcata aggttcgtgt tagtgatcga caagaaatct
     1081 gtagcgattt caaattagtt tatcaagcaa gttcaaaaga agaagcaaat aatcaaataa
     1141 ggtttatgat agataaatgg aaaaagcagt atccacgagt ggttaaattg ctcatgaatc
     1201 ctgctatatt aaccttttat aatttccctc cgtcaatcag aagaactatt tattcaacta
     1261 atttgattga aggttttaac aaacaattaa agaaatatac caaaagaaaa gagcaatttc
     1321 ctaatgaaga atctctggag agatttctag tatctcaatt caacaactat aatcaaaagt
     1381 ttctatgccg agttcataaa ggttttaaag aaatacatga tacattagaa tcaatgtttt
     1441 aacttgatca acaga
//
LOCUS       DAFLWQ010000210         1389 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.218, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000210 DAFLWQ010000000
VERSION     DAFLWQ010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1389
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.218"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            154..417
                     /locus_tag="L1V16_003075"
     CDS             154..417
                     /locus_tag="L1V16_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBN1277334.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            417..689
                     /locus_tag="L1V16_003076"
     CDS             417..689
                     /locus_tag="L1V16_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBN1277335.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            766..1095
                     /locus_tag="L1V16_003077"
     CDS             766..1095
                     /locus_tag="L1V16_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBN1277336.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            1085..1372
                     /locus_tag="L1V16_003078"
     CDS             1085..1372
                     /locus_tag="L1V16_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBN1277337.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
BASE COUNT          526 a          169 c          277 g          417 t
ORIGIN      
        1 ctctaggaaa aaattaacta gcaccacggg tataaaggaa acggataaca ctttacaatg
       61 ctgttttggt actccaattt aaacaaaaca atcgaattta cgtacttaat taagtacgtt
      121 agaatggaga tataaattag agggggagta gatatggcaa aaacagtctt aaatcctagc
      181 tcagcacgga aaaattttta taagttgttg aaagatgtaa atgagaatca tacggaaatt
      241 gaaatcatta gtgagcgcag tgaaaataat gcggtgctta ttggtttgga tgattggaaa
      301 gcaatcaaag aaacgctatt acttgagcaa ataggcactt tgggtgttgt tcgtaagcga
      361 gaaaaagatg atagtggatt tactaatgtt gatgaaattg attgggataa cttataatga
      421 ataactattc tgtgatgatt aaaaactcgg ctaaagctga tttaaagaaa atcaaacagt
      481 ctaatttgaa acctcaattt gagaaggtta ttcagacttt aaaggaagat ccctatctcc
      541 ctacccaatc atttgagaag ttaaaaccta cacatgaagg taggtattct agaagattga
      601 atagacaaca ccgggttgtt tataaggtag atgaagatga acacgtggtt gaaatttatt
      661 cagcaaggac gcattacgag tcacagtaat tacttgtaaa tacattatct cgtggtataa
      721 tgtatttact aagtaattac atactgttag aaatgaggga tttaaatgat tacaaaaaca
      781 agaaaacaag gcaattcaat catgttgaca gtacctaaag attttaatgt tcctaatgga
      841 gtcgaagttg aagcaaagtt ggtagagaat ggtattcttt atgaatttgt tgaaccacaa
      901 aaagaatttt atgattttag cgaagatatt ttgtctgata taattgcaga aggctacgat
      961 aaagatgaga ttcttgtaga atttaagaat agaaaaaaca aaatgcattc ttcctttaga
     1021 gatattgctg aagatacact tactaattct aaagtaatga ctaaagagga gttggcaaca
     1081 gaaattggct tatgaaatcg ttccttcaaa acatgtcatt aagtatttaa aaaagctaaa
     1141 agagaagcca ttgaaagaaa aatttttgaa tttaatttat gatgaaattg cgattgatcc
     1201 atataagggt gaacaaaaaa ctggggattt atcaggtatt tggtctagtg ggttcaaata
     1261 tgcgggcaca acatatagag tagcttacga gattatagaa aacaaggtta ttccagtatt
     1321 gttatgtgga acgcatgaaa acttttatga acagttgaaa aaattaatct agtgatttgt
     1381 tgtcgttct
//
LOCUS       DAFLWQ010000211         1377 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.219, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000211 DAFLWQ010000000
VERSION     DAFLWQ010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1377
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.219"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(680..753)
                     /locus_tag="L1V16_003079"
     tRNA            complement(680..753)
                     /locus_tag="L1V16_003079"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(717..719),aa:Ile,seq:cat)
     gene            complement(943..>1377)
                     /locus_tag="L1V16_003080"
     CDS             complement(943..>1377)
                     /locus_tag="L1V16_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1277338.1"
                     /translation="TDENPTTSENKPVIDPTRAGAANPTLTDGTNHAHIDQFGEIENA
                     NLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYHVSFN
                     MRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          426 a          251 c          241 g          459 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcatga ctgacgtgcc ggacgcacgt agcgatcatc ggcgttatga
      121 ctatataaag tatactttcg ttgatccaga aaggtataaa gattaaagta ggctacctaa
      181 aaaggtagcc cggaacgaat tttatcacca tacttgtgaa aggagatatt ttttaagtta
      241 gtattaagat tgtgtaatat gatgatatct atattttata gtatcagtgc tataaaatca
      301 aaaataagtc actaattaac taccactcca attgtaagcc ttttttctca ctttttttca
      361 aaaatatggt atgcttttta atggcttcaa atataaaaga gtttaaagcg taacacactt
      421 atggggaagt ggtttggggt gcgctttaaa ctcttcttta ttattatctc acaatttaac
      481 ccaaatgtct ttctatttaa aaatcaaagt aaaacttttc aaatatacag aagtataact
      541 atgtgaaaca tcctttcatt aatccataaa aggatacata aaaaagccac tcatttgagt
      601 ggcaatgaag aaaagcttta gcttgtataa tactcttcaa aaaaattcta acacagaacg
      661 attcaaatgg ctacgttaat gtaccctgta ggactcgaac ctacgaccgg acggttatga
      721 gccgtctgct ctgaccaact gagctaaggg tactggttgt tgccacataa agccataaac
      781 aatcaaccag tagaatgtgt ggcaacaaac ctgttatcgc atagcttgga gtgtgactat
      841 ttatgggtga tagtgaagat atgcgataac atcactattt tatcgaataa tttttatagt
      901 tgtcaatata gttatgtact gctcctcaac gaggagctat ttttatcgtt taggaatatt
      961 taaataccaa cgtttgtcat ggaaatcttg cgcaccgcct ttagtgtttc cctctggatc
     1021 attcgttgcc cgcatcatta catagacttt cttactagga aaattacgca tattgaaaga
     1081 tacatgataa ccaacatttc cagaagtatt ataagcttgg tttacatctg gtctataaat
     1141 tccatcagct cttactcgag ctaattcttt cccagtattg tagtccataa tgaaaatata
     1201 ctcgtattta tagttagcaa tgtgccatcc agccacatgc aagtttgcgt tttcgatttc
     1261 cccaaactga tcaatgtggg cgtgatttgt tccatctgtc agcgtaggat tagctgcacc
     1321 agctcgtgtt ggatcaatga caggcttgtt ttcagaagtt gttggatttt catcggt
//
LOCUS       DAFLWQ010000212         1364 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.220, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000212 DAFLWQ010000000
VERSION     DAFLWQ010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.220"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            80..>1364
                     /locus_tag="L1V16_003081"
     CDS             80..>1364
                     /locus_tag="L1V16_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HBN1277339.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLI"
BASE COUNT          465 a          263 c          257 g          379 t
ORIGIN      
        1 tttaggtatt aaaaaacata tcgttctcta gtatgattaa atcaccacaa aataaacaac
       61 tgagaggacg atacgctata tgaatgattc tatcaaaaaa atgctgagaa taacagagaa
      121 agatttgatg attacagagg tctcttacga gacccttcag aagaaaaaga cgttggtcgt
      181 cgatgctgtt ctctcgccta ctcctcgtgc ttgtagaagt tgtggttcta ctgtggtaga
      241 tggaaacggg aaagcaatta tagtgaaaaa tggaaaaaag gaaacgattg tccgttttga
      301 acaatacaat catatgcctt tggttatgcg cctaaaaaag caacgctata cctgtaaaaa
      361 ctgtcgcacc cattggacgg ctcaaagtta ttttgtccaa cccagacatt caatcgcaaa
      421 tcatgttaga tataaaattg cttctttact gactgaaaaa gtatctttat cttttattgc
      481 gaaaagctgt caggtatctt tgaccaccgt tattcgtaca ttgaaagagt ttaaaagcta
      541 tttaccaaag caatctaaga agatcctccc cagagtattg atggttgacg aatttcgttc
      601 gcatgcttcc atagaagata agatgagctt tatttgcgcg gatggcgaaa caggaaaatt
      661 aatagatgtt ttgcctacgc gtaaattacc tcgattaaca agctatttct taggttgtac
      721 caatccagaa gaagtagaat tcttggtgac agacatgaac gccgcctact tccagctcac
      781 caaacgtgtt ctgccaaatg cgaaagtcgt gattgatcgg tttcatattg tcaaacacat
      841 gaatcaagcg ttcaatgagt tgcgtatccg tgaaatgaat gaacttcgta aagccggaca
      901 gaaaagccag gcagaaaaac tgaaaaagaa ctggcgcttt ttgctaaaaa atcgtgcaaa
      961 catcaaccat tatgaataca aaacatggaa aagtttccga gcaccaaaat acccatttct
     1021 tactgaagca atgatgattg atcgattgct tgagttttct ccgcccctaa aggaggcgta
     1081 tccctttttt catgaattag ttgaagcctt tcgagacaaa gaccctgact tatttttctc
     1141 cttattggca gaacttcccg aaacgttaga tgacagcttt cgggaaaagc ttcaaaacct
     1201 tctgacctat gaagaaggca tcaccaacgc aatgatctat ccttattcca atggaaaaat
     1261 agaagcgaag aatacccaca taaagacaat gaaacgagta tcctacggat ttaaatcatt
     1321 tgagaacatg agaattagaa tctttttgat caatcaatta atca
//
LOCUS       DAFLWQ010000213         1358 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.221, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000213 DAFLWQ010000000
VERSION     DAFLWQ010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1358
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.221"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            557..1090
                     /locus_tag="L1V16_003082"
     CDS             557..1090
                     /locus_tag="L1V16_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBN1277340.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT          432 a          249 c          254 g          423 t
ORIGIN      
        1 atatttttcg tttggttggg cttattaccg cagatgcaag cttttgaaca ccgtttatta
       61 agaggttgtg aaaaagctgc actgcatcaa gtaataagaa cagccaaaca aaaatagttc
      121 ctcatatttt tcgtttggtt ggacttatta ccgcagatgc aagcttttga acaccgttta
      181 ttgagaagtt gtgaaatcag cgtcctgacc tgagtattag agaaacaaat ggcaaaatag
      241 ttcctcatat tttgctattt tttgagctaa taccgagggt cagctgattg aacaccgttt
      301 agtggagaag ttgtgaaaaa gtcgcctact ttcgagtcgt aagaaatttt tttgaaaatg
      361 gttcctcaca actttgcata aatttgactt aataccgaga agtcatgatc cccatctaac
      421 tccaaatcac aaggaatgag ttcaaaaact agcttttctc aacaaatatt acataaaaaa
      481 ttctatgttt tttgttaaat ttatttgctt ttttcaaaag tatgttacag taatttccca
      541 aggaggtttt acagaaatga attttgttgc catggatttt gaaactgcca atcatcagcc
      601 ttatagtgct tgttctcttg cgctagtcat ggtaaaaaat agccagatcg ttgatgaatt
      661 ctatacattg atacagcctg agactccttt tttctggcga aatgtccaaa ttcacggaat
      721 ccatcaagaa gacgtacgca atgcgccgaa attcccagaa gtctggcaaa ctatccaacc
      781 atattttcaa aaaaatcgtt tagtcgttgc acataatgct gcttttgata caaaggtctt
      841 agcgggatgc ttagattatt atcatcttga acagcctaat tatctttctt tatgtacagt
      901 gaaaagtagc cgtcgcctgt ttcctgaatt tccaaatcat cgattgaaca ctgtgtgcga
      961 aaatttgaac atccaattag atcatcacca tgatgcattg gaagatagtc gtgcatgtgc
     1021 ggaaatcctg ctttatcaag aaaaaaaatt cgggacagat ccattgaaaa aacttgtgac
     1081 tataaagtaa aagaatactt atgaaacaca caaagaggtc gtgagcctgc cgtttcactc
     1141 cgagtcacaa ggagcaattt caaaaaatag cttctcatgt ttattaaata ttgtgactgg
     1201 tgaccgagga gctggcagga gaacaccgtt tattggagag gttgtgaaaa agctgttctg
     1261 catcaagtaa taagaacagc caaacaaaaa tagcttctca tatttttcat ttggttggac
     1321 ttattaccgc agatgcaagc ttttggacac cgtttacc
//
LOCUS       DAFLWQ010000214         1355 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.222, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000214 DAFLWQ010000000
VERSION     DAFLWQ010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.222"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..1355
                     /locus_tag="L1V16_003083"
     rRNA            <1..1355
                     /locus_tag="L1V16_003083"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          362 a          295 c          415 g          283 t
ORIGIN      
        1 caagctgtga tggggaggga aataatagta ccgaagttcc tgatgtcaca ctgccgagaa
       61 aagcttctag tgagaaaaca gcggcccgta ccgcaaaccg acacaggtag tcgaggagag
      121 aatcctaagg tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt
      181 cgggagaagg ggtgctgatc atacgatcag ccgcagtgaa taggcccaag cgactgttta
      241 tcaaaaacac aggtctctgc aaaatcgtaa gatgaagtat aggggctgac gcctgcccgg
      301 tgctggaagg ttaagaggag tgcttagcgc aagcgaaggt acgaattgaa gccccagtaa
      361 acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcggg taagttccga
      421 cccgcacgaa aggcgtaacg atttgggcac tgtctcaacg agagactcgg tgaaatttta
      481 gtacctgtga agatgcaggt tacccgcgac aggacggaaa gaccccatgg agctttactg
      541 tagtttgata ttgagtgtct gtaccgcatg tacaggatag gtaggagccg tagaaatcgg
      601 aacgctagtt tcgatggagg cgctggtggg atactacccc tgcgttatgg ccactctaac
      661 ccgcaccact aatcgtggtg ggagacagtg tcagatgggc agtttgactg gggcggtcgc
      721 ctcctaaaag gtaacggagg cgcccaaagg ttccctcaga atggttggaa atcattcgaa
      781 gagtgtaaag gcagaaggga gcttgactgc gagaccaaca agtcgagcag ggacgaaagt
      841 cgggcttagt gatccggtgg ttccgcatgg aagggccatc gctcaacgga taaaagctac
      901 cctggggata acaggcttat ctcccccaag agtccacatc gacggggagg tttggcacct
      961 cgatgtcggc tcgtcgcatc ctggggctgt agtcggtccc aagggttggg ctgttcgccc
     1021 attaaagcgg cacgcgagct gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc
     1081 gcgggcgttg gaaatttgag aggagctgtc cttagtacga gaggaccggg atggacttac
     1141 cgctggtgta ccagttgttc tgccaagggc attgctgggt agctatgtag ggaagggata
     1201 aacgctgaaa gcatctaagt gtgaagccca cctcaagatg agatttccca tttctttaag
     1261 aaagtaagat ccctgagaga tgatcaggta gataggtcag gagtggaagt acagtgatgt
     1321 atggagcgga ctgatactaa tcgatcgagg actta
//
LOCUS       DAFLWQ010000215         1340 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.223, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000215 DAFLWQ010000000
VERSION     DAFLWQ010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1340
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.223"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            7..624
                     /locus_tag="L1V16_003084"
     CDS             7..624
                     /locus_tag="L1V16_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277341.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     GKRTIVEVSSTYPTTMILSLLISSITFIFLFTRYLIRCCGEMKID"
BASE COUNT          504 a          171 c          208 g          457 t
ORIGIN      
        1 agaaccttgg gttttcaagt gctttttggt tcattaatct taaccatagt gtttttaaag
       61 tggaaaacaa gcaacaaaaa aagtatgtgg agccttgtag gaatagttct tattattttt
      121 actgtgactg cagcaacaga agcaaattat tcgcataaaa ttcagtcgta taaaggtcgt
      181 ttagttatga ccaaaaaaga tgttacacgt tatacatcct caagaactgg aggcctatat
      241 gactatgcac cattagatgc attgaaatat aaagatcatt taaagaaaca tgaagtaaaa
      301 gttggtgatc ggtgggagaa tgcatctcat aaagcatata attccaaaat agtctataca
      361 gtagaagatg ccgatgagca aaatatcaca ttacctgtat tcaattattg gggaacagtt
      421 gtgaaagtaa atgggaaaaa gagcactata gaaaatgaca atggtttagt gtctattaaa
      481 ggtacgggga aaagaactat agttgaggtt tcatctacgt atccaactac gatgattcta
      541 tctttattaa ttagttcaat aacttttata ttcttattta cacgttattt aataagatgc
      601 tgcggtgaaa tgaaaataga ttagatagat attataaata tgttgattct attttcatag
      661 caatggagaa aatacattag caatatataa aagaaggtat caagagtcac agtgaattta
      721 ttccgaaaag tgaaaagagc aaatataaaa tttaatgaaa atatagaact aaataggaaa
      781 acgtagacgt aattttctac gttttccttt tcatatatat taaatattac ggaaaattat
      841 ataaactaat ttagtgtttt gtttgtaatt cctaattttg ctccactttt agataatttt
      901 taggtctatt taactcatca gacattctat gctcattttt ctccaaattt gtttcaactc
      961 tttcgtactt aattttgcgt atttgaaaat tcttctttta gagtactttt attacgatac
     1021 tagtatgata tatatctata gcaaacagtt aaaatcttcc taaaataagc gaatagcatt
     1081 cctaaaacct ataaaatttt tagatgaagc gacaagtgga caattaataa actacttgaa
     1141 catgaaatta tggatcacct ttcaaattta gaaaatggaa ttcttatact tattgcgcaa
     1201 catttattga ttgcaaaatt atgtgacaaa aaaaactagt agaagaaaga ataatggctt
     1261 gataataaag tactacctat taaaggtagt actttattta atttagtata aattaacata
     1321 ctactatatt ttaggtttca
//
LOCUS       DAFLWQ010000216         1324 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.224, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000216 DAFLWQ010000000
VERSION     DAFLWQ010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1324
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.224"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            55..1217
                     /locus_tag="L1V16_003085"
     CDS             join(55..331,331..1217)
                     /locus_tag="L1V16_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBN1277342.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKW
                     VKQSKTSGSFKEKDNLTPEQKELLELRKRNQQLEMENDILKQAALIFGPKRQVIDANK
                     HLYPISAMCRILGLSRQSYYYQSKPKKDESELEEVVAEEFIRSRKAYGSRKIKKALSK
                     RGIQISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKTTNVLNRKFLRDNPLEAIV
                     TDLTYVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLVKKAFSRIKQPLTEVEIFH
                     TDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAVAESTYKSLKVEFVYQYTFETLQ
                     QLDLELFDYVNWWNHLRLHGTLGYETPVGYRNQRLAQRILDNELGCANASEAV"
BASE COUNT          478 a          234 c          265 g          347 t
ORIGIN      
        1 gacagaaaaa ttaaggtgtg tagactagaa gaaaacatac caggaggaat ttttatgtct
       61 aagagaacac gaagaacttt ttcacaagaa ttcaagcaac aaatcgtcaa tctttactta
      121 gctggaaagc cacgtgtaga aatcattcga gaatatgaac taacggcttc agcatttgac
      181 aaatgggtaa agcaatctaa aacgagtggt tcattcaaag aaaaagataa tcttacgcct
      241 gaacaaaaag aattgttaga actacgtaaa agaaaccagc aattagaaat ggaaaatgat
      301 attttaaagc aagcagcgct gatattcgga cgaagagaca agtaatcgat gcgaataagc
      361 atctttaccc tatatcagcg atgtgcagaa tattaggtct atcacgtcag tcctattatt
      421 atcaatcaaa accaaagaaa gacgaatcag aacttgaaga agtagtcgct gaagaattta
      481 tccgcagccg aaaggcctac ggctcaagaa aaataaaaaa agccttatca aaacgaggca
      541 ttcagatcag ccgacgaaaa attagtagaa tcatgaaaaa tagaggatta aaatcgagct
      601 atactgttgc ttattttaaa gtacatcatt ctacttgcaa tgaagccaaa acgacaaacg
      661 tattgaatcg taaattctta agagacaacc cattagaagc gatcgtaaca gacttgactt
      721 atgtacgagt cgggaaaaaa tggaattatg tctgtttcat tttggatctg ttcaatcgag
      781 aaattctcgg ctattcttgt ggagaacata aagatgccgt tctagtaaaa aaagcattta
      841 gccgtatcaa acaacctctg acagaggttg agatttttca tactgatcgt ggaaaagagt
      901 ttgataacca agctattgat gaattattaa caacttttga catcaatcga tcattgagtc
      961 ataaaggctg tccttttgat aatgccgtag ctgaatcaac ttataagtcg ttgaaagtag
     1021 aatttgtcta tcaatacaca tttgaaacct tacaacaatt ggatttggag ttatttgact
     1081 atgtcaattg gtggaaccac cttcggttgc acggtacact tggctacgag acaccggttg
     1141 gttaccgtaa ccagagattg gcgcagcgaa tccttgataa tgagctcgga tgtgctaacg
     1201 ctagcgaggc agtctaactt taactgttag ctcctgccga agatcgtcac atccgaggag
     1261 gctcattgtc aaggacaatc ggaatagcat acggaaagaa gttctgcacc ttataaaatt
     1321 tgtc
//
LOCUS       DAFLWQ010000217         1308 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.226, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000217 DAFLWQ010000000
VERSION     DAFLWQ010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.226"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..863)
                     /locus_tag="L1V16_003086"
     CDS             complement(<1..863)
                     /locus_tag="L1V16_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277343.1"
                     /translation="MATNYAKKINFDVDKLYKSLIVVPKNKSEDGNYELEVLQFKIEQ
                     KSSERFMSNQLVKIKKWLPMIDQLVSNNKEAKNLCIFVLLLHGRVINLVNRKSTTKFA
                     NSFWFLENINETVEKNGVYKGDFHFQNAETIEREHHYFDLLVNTVVELAKWAKSNETY
                     SQVLKRIMSQETSFIYELSKSNLKYTYNEDELEILDNPENSQWIKELKREDFIETLRI
                     LKSLFDLKLAKATIMGIERDSYYWEEIGLYAPQIEGEDKEKRIDNIINYINSLSEPLK
                     CRGLDFIGTLG"
BASE COUNT          424 a          236 c          131 g          517 t
ORIGIN      
        1 catcctaatg ttcctataaa atcaagtcct ctacatttta aaggttcact taaactatta
       61 atatagttaa taatgttgtc tatccttttc tctttatctt caccttcaat ctggggagca
      121 tatagtccaa tttcctccca ataatatgaa tctctttcaa ttcccatgat ggtagctttg
      181 gctaatttca aatcaaataa cgattttaga attcttagtg tctcaataaa gtcttctctc
      241 ttcaactctt taatccattg tgaattttct ggattatcta aaatttcaag ttcatcttca
      301 ttataagtat atttcaaatt tgacttgctt aactcataga taaatgaagt ttcttgactc
      361 ataattcttt taagtacttg actataagtt tcgtttgact ttgcccattt cgctaattct
      421 accactgtat tcactaataa atcgaaataa tgatgttctc gttcaatagt ctcagcattt
      481 tgaaaatgaa aatcaccttt ataaactcca ttcttttcca ctgtttcatt aatattttct
      541 aaaaaccaga atgagtttgc aaatttagtc gtactttttc gattaactaa gttaataact
      601 cttccatgta ataataagac aaaaatacat aaatttttag cttccttatt attagatact
      661 aattgatcaa tcatagggag ccattttttg attttcacta attgattgct cataaatctt
      721 tcactggact tttgttcaat cttaaattgc aaaacttcta attcataatt tccatcttct
      781 gatttatttt tgggaacaac tatcaaactt ttataaagtt tatccacatc aaaatttatc
      841 ttttttgcgt aatttgtagc cattaataca tctccttatt cataataaat ttcatatgac
      901 gctcctctca aaatttaccg gtagactaga aaaaagaata aaagatacgt caattcacac
      961 tttattctta aaaaaaactg gtctctctac cggtaatatc gattgagtcc gcctttatcg
     1021 actttatcct ttttttatat taaatgtttt caccggtaga cagggagaga aagaataaac
     1081 taaaagccct taattcttaa tgttttcacc tccttaccgt tcctaccgct aaaatttaat
     1141 ataactaaat tctataacat tagaagaaat tttaaatacc tttgataaaa aatattgatg
     1201 ttttttctct cattgtttac aaactagata gcttatgtat tcttattaaa aataatagat
     1261 atttcgaaca tcatcactct catctactta atttcgcatt tttacttt
//
LOCUS       DAFLWQ010000218         1276 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.227, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000218 DAFLWQ010000000
VERSION     DAFLWQ010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1276
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.227"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            35..532
                     /locus_tag="L1V16_003087"
     CDS             35..532
                     /locus_tag="L1V16_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1277344.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
     gene            complement(569..1252)
                     /locus_tag="L1V16_003088"
     CDS             complement(569..1252)
                     /locus_tag="L1V16_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277345.1"
                     /translation="MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGIK
                     IGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFAQLSE
                     ALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLY
                     DNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKANGVTELAIYQKG
                     KRIMVPLPV"
BASE COUNT          444 a          216 c          224 g          392 t
ORIGIN      
        1 atttatagta tactatgtca aaaggaggag ttagatgaac aatcaaatca cactagcgta
       61 tttagattat gatgatctag atgctttaca agttgtaagt gttgtcagtt tttatgaatc
      121 gtttatcgat ggcgcagatc cacttgatat gcaaggatat ttacagacac aattgacaac
      181 tgaaatattg gcagtagaat tggcacagtc aaccagtaaa tttattggta ttaaggatca
      241 tcaaatactc attggttata tgaaagtcaa tgatgaaaaa gatgctatag agattcaacg
      301 gctctatctg ctcaaagatt atcaaaacaa agggttaggg caacggttac tcgatgaagc
      361 gaatcgttat gctaaaacga aacaaaaacg ttatttacgt ttgactgttt atgaaaaaaa
      421 tcatgcaggt attcgttttt atgaacgtca tggatttaaa aaaatcggga tcaaacattt
      481 tcctttagga aaacaagatc gtatttgtcc gattttagaa aaagaaatct aaaaaaacgt
      541 cctcactttt gatgctgagg acgttttttt agactggtaa tggaaccata attcgctttc
      601 ctttttgata aatcgctaat tccgtcacac catttgcttt taacagagca aaaagatcat
      661 cgaaatggaa acggaaatgt tcaaggtaat gcccatctga tccaacacta aacaaggtac
      721 caccacgtga aagatataaa tcgatgacat attcatataa cgctaaattg tcatacaagt
      781 aagcgctctt agcatttaat tcgaatgcca atttattttt gattacttga tctagaatcg
      841 gtaaaaactg cgcttcatat tgtttaaatt cagcaacgga tagaccaaat acccgaaaac
      901 catagtcaaa atgagcaaag acatctgctt ctataacaac tagtgcttct gaaagttgtg
      961 caaaatactg aggaatcaca atagcaggat ccatatcttt gacttcgtca tctaaataat
     1021 caaattgccc attatgatgc acactgagta attttaaatc gtaatcttta tcggctaaat
     1081 agtcgatgat ccgatccttt tcagaagcga tgtaaccgat tttgatgcct tttaaaacac
     1141 gattgccaaa acgcttattt aagctatcga ttgtttgact gtacatttca taatcgggga
     1201 tatcatcgac tttagtaaca ggattggcta agtcaaaatg ttcagttgtc acgacgtaac
     1261 catcgtagtt tgttaa
//
LOCUS       DAFLWQ010000219         1259 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.228, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000219 DAFLWQ010000000
VERSION     DAFLWQ010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1259
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.228"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            230..1087
                     /locus_tag="L1V16_003089"
     CDS             230..1087
                     /locus_tag="L1V16_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1277346.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            1088..>1259
                     /locus_tag="L1V16_003090"
     CDS             1088..>1259
                     /locus_tag="L1V16_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277347.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQ"
BASE COUNT          465 a          183 c          253 g          358 t
ORIGIN      
        1 gtctacatga ctaaagtcgc gagtattctc tgcttctcga taaattaaat aacgtcatta
       61 ctttgaggaa agctataaat caatatattt cagcttttcc ttatttatgt actacctttt
      121 acttattaat tataaggtag tacatatata tctttttttg gtagtaacta aaaataaata
      181 tgttataata gtatcaaatg aatattgcta aaagaaaaga ggtaggaacg tggtagcgaa
      241 gaaatatgta atcggtaatt ttaaaggtgg cgtaggtaaa agtacgtgcg cgcaaatgtt
      301 agggtttgaa tcagcagtta atgaaggaaa aagaaccttg ataattgact tggatatgca
      361 aggaaatact tctgatgtga tgaacttaac gcatatgaac ttcactaacg aagaaggagg
      421 cggagaaggt gaaccgattg tttacgaaaa tactgtgact gacgtgttga taaacaatct
      481 tccacctaaa gaggctgtct ataaagtaat caataacctc tatatacttc cagcagacat
      541 gtcctttgaa atgtatgatg attggatcaa agaccaatat aatgattcat tatcccaatt
      601 caaatatatg aaagaaaagc tagaaccatt atttgatgag tttgacgtca tctatttaga
      661 tgtcccacct tctatttctg tatatagtaa atccgcgatg tacattgcgg attgggcaat
      721 cgtcgtctta cagacccaag taaaatcgat gagaaatgcg atgcaatatc ttgagtatat
      781 ggactttttt gtgaaagaat ttgatacaaa tttatatgtt gctggtgtta ttcctttcat
      841 gttggaaagc ggtgacgcag tagatcagga aatgtataaa caagcccaag agatttatgg
      901 ggaacatttg attaaaaatg ttgtactcaa aaatgcgcgc ttaaaacgat acgacggatc
      961 aggtattacg atggagaaga caaagaaagg tctcttaaaa caatgggatc gcaaaagcca
     1021 cgaattattt atcagtattt tgaaagaatt ggaagaacac gagaattggt atgcggaggt
     1081 ggagtaattg gctgacatca aaggacttga tatttttggg aacaacaaag gactcgccaa
     1141 aataaaaaaa gaagcagaag caaagaaaaa gcagcaagca attacaccat ctgaaaataa
     1201 gcaattagaa gtgcaccaag ttcaagaaat aaaaacttcc tccaatgttg aaagacaga
//
LOCUS       DAFLWQ010000220         1253 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.229, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000220 DAFLWQ010000000
VERSION     DAFLWQ010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.229"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(407..1111)
                     /locus_tag="L1V16_003091"
     CDS             complement(407..1111)
                     /locus_tag="L1V16_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277348.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT          369 a          216 c          228 g          440 t
ORIGIN      
        1 gagagactcc tttggtaggg tgacgttttg gtcgactaaa ttttaccaaa agtgagtctc
       61 tttttgagtt gaaacgaaga aaaaagtgtt agtagaaaat cgctttcgat tttccaccaa
      121 cacaaaatat tatagaaccg cttttttctc tatcagaaaa tatgtttatt attagaattt
      181 tttatagtta aggttaggca tcttaagaaa tcaggcaact ccaagatatc ttcaggtaga
      241 agagaagtcg cctaacattg taggatcata ggtgatttgt tggacaggtc aagctgatat
      301 ttgagcctga tgttagaagg aatttctttt tacttgctgt agaaattatt atatgactaa
      361 aaaggctggg attttaaatc ccagcctttt atgacaaata gaatttttat cgatcagtaa
      421 tcgctgtcgc tgcaaattgt tcgatcaaag gaatcaaagt caatttgact ttgtatttcc
      481 gttcgagtgc tttttcgata acgaactcat tttcagtagt catagaaata gttgctaatt
      541 tacgaggttc atcagcattt ttttcattaa taactacttc atgttcattt tgttctgtgt
      601 aaaatttagg atactcagca acggcttttg aaaaatcagc aaaacttaaa gcggcattcg
      661 tatcagttga gcgtgtattt tcagttgtgt ccgcttttgg tttttccgtt ttttcttctg
      721 gcacactgac tgtttcttct gtaactggtg tcgcaacagc ttgcgcagtt ggttcatcgt
      781 ttttcaatcg ttgatcattc cagtaagaca cgatttcaat aagaagattg tcacggaatc
      841 gttcgaaaat cccgttttct cctgaacgaa ttctctttaa tacagtattg aagttgtcat
      901 cgattggcac gttgatccgt gtatcttcat ttgttttccc agctaatccg atcgttaaga
      961 tttgacggtt tttgggatca agcatgactt gtaacggcaa accataacgt cgcaagctct
     1021 cttcttctag agaacggaat aattgtcctc ttacaccatc caatgaagga cggaattgat
     1081 ttaataattt ttgtttctgt tttttcttca tatgttctct ccttcgctca taccctttcg
     1141 attataagaa aaaaacagcc aaatgaaaag gagtaatgca aaaaaacttg cgtatacgca
     1201 aattacaaca gaaaaatttg cgtattttcc cgttttttga aagaaaaata aaa
//
LOCUS       DAFLWQ010000221         1246 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.230, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000221 DAFLWQ010000000
VERSION     DAFLWQ010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.230"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            200..742
                     /locus_tag="L1V16_003092"
     CDS             200..742
                     /locus_tag="L1V16_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277349.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1246
                     /locus_tag="L1V16_003093"
     CDS             898..>1246
                     /locus_tag="L1V16_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBN1277350.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DAFLWQ010000222         1237 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.231, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000222 DAFLWQ010000000
VERSION     DAFLWQ010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1237
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.231"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..1228
                     /locus_tag="L1V16_003094"
     CDS             <1..1228
                     /locus_tag="L1V16_003094"
                     /inference="COORDINATES: protein motif:HMM:NF016309.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277351.1"
                     /translation="SLESLKKEAKYRIDKRYNWKPIGSKNLVDQKTISQLQIHPEKRG
                     LLYTPSRIIKYDIIENQWIKFILSYFKNFSLLADRYLEKILQGIIEEKKREDKFTSAY
                     SQSVQNYNTNSYNRKIENLKNNQQKIKHFYAYILEFLDTPVMKNISSRRPINVPKSLV
                     MNPKYNTIYKMYLKSRNNRNTLNFSNRYQYYWKSTDVLYEIWCFIKIIRSLSLQGYTP
                     ISGWIFENDILSQELPFLHEDTTVVLSKNDIRINLVYNNSMEKEYFSNTLDIPVKTSS
                     KRNKPDIRLDIILQDKYYIGSLIFEVKYKKLDNILDNDKGRQRQQLMAYKQNTMSSIL
                     AFPEILTRSLQAVSAVFALYPSNEGRKKTAPKYYEKEGIFFHLLNPSSDEKELSVKIQ
                     TSIEERISLFNQQSRN"
BASE COUNT          517 a          177 c          160 g          383 t
ORIGIN      
        1 ttctcttgaa agtttaaaaa aagaagcaaa atatagaatt gacaaacgat ataactggaa
       61 accaattgga agcaaaaatt tagtggatca aaaaactatt tcacagttgc aaatccatcc
      121 agaaaaacgt gggctactat atacacctag ccgcataata aaatatgata ttattgaaaa
      181 tcaatggatc aaatttatct tatcttattt taaaaatttt tcacttctag ctgatagata
      241 tttagagaaa atcctacaag gtattattga agagaaaaaa agagaagata agtttactag
      301 cgcgtattct caaagtgtac aaaactacaa tacaaatagc tataatagaa agattgaaaa
      361 tttgaaaaac aatcagcaaa agataaaaca tttttatgct tatatccttg aatttttaga
      421 cacaccagta atgaaaaaca tttcatcaag aagacctata aatgttccaa aatcacttgt
      481 tatgaaccct aaatataaca ctatatataa aatgtattta aaaagtagaa acaatcgtaa
      541 tactttaaat ttttcaaata gatatcagta ttattggaaa agtacagatg tactctatga
      601 aatttggtgc tttataaaaa ttattagatc tctatccctg caaggctaca ctccaatttc
      661 tggatggatt tttgagaatg atattctttc acaagaattg ccgtttttac atgaagacac
      721 taccgtagta ttgagtaaaa atgatatacg tattaatctt gtatataata attccatgga
      781 aaaagaatat ttctccaata cactagatat cccagtaaaa acctcttcaa aacgaaataa
      841 acctgatatt agattagaca ttatccttca agataaatac tatatcggaa gcttaatatt
      901 tgaagtaaaa tataaaaaac tagacaatat acttgataat gataaaggta ggcaacgtca
      961 acaattaatg gcttataaac aaaatactat gtcaagtatt ctagcatttc ctgaaattct
     1021 tacacgttct ttgcaagctg tctctgctgt ctttgcttta tatccttcca atgaaggaag
     1081 aaaaaaaact gcacctaaat attatgaaaa agaaggtatt ttttttcact tattaaatcc
     1141 ttcatcagat gaaaaagagc tttcagtaaa aattcaaaca agtattgaag aaagaatttc
     1201 attatttaat caacaaagta gaaattaaaa agatgaa
//
LOCUS       DAFLWQ010000223         1233 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.232, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000223 DAFLWQ010000000
VERSION     DAFLWQ010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1233
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.232"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            27..980
                     /locus_tag="L1V16_003095"
     CDS             27..980
                     /locus_tag="L1V16_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1277352.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            952..1227
                     /locus_tag="L1V16_003096"
     CDS             952..1227
                     /locus_tag="L1V16_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HBN1277353.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
BASE COUNT          446 a          189 c          235 g          363 t
ORIGIN      
        1 tttagtatag gaaattggag ggaactatgg aaaacttacg gactgcattt aaaacatcag
       61 ataaactagg aaaagttgta atgcttacag gtagaaaagg cggcattggt aagactacag
      121 acaatgattt attagcgatt gtttctagtc aactttttga aaaagacgtg ttgctaattg
      181 attatgacca acaaagaaat actacttcca acattggatc aacgtatcaa attactagct
      241 ttgatcgatc catgtctgca gcaatcaaaa aaggggactg ggtttcaggt attactcaag
      301 taagtccaca tttatatatt atggctggct ctcctggatc tgaagaactt aatgaatact
      361 tgtccgaaaa atatcctgat cgtcgtaaga gatcattggc cttcattaaa cctttagaag
      421 aattgagaaa aaatttcgat tatatcttta tcgactgccc accatcaaca gataatgtgg
      481 ttcgtgcatt cttaactgct gcagattata ttattgcaat gcaagaatta aaacggtacg
      541 caatggaagg aacagaagat tttattaata aagttttagt tccgattgtc acgaattttg
      601 aagagtctca tcttcaaatc attggaattt tgcctgttct tttctcagtg cgacgttcct
      661 ctcaacacgc aaactatcaa aaaacaattg ataagtatgg tgaatcaaac atttttaaaa
      721 gcattgttaa aggctcggat cggttagaaa tgtatggtga gaatggtatc caattaaatg
      781 attatgtaga tcgaagatgg tgggctattt ttgcagacat ctttacagaa ttagaagaaa
      841 gaattgaata ctatgaacaa catggtgata ttgaaggatt tgattataca cctaaatatg
      901 ctgactcaat ggccaatcat atcctacctc ttggaaagga gattaaacta aatggcatta
      961 ttaccaacga acaaagataa gaagaaaatt ggtgctgaag atatttcaat taaagatgat
     1021 attaatgtcg agttagggga acgaaagtac actgcgaaag aaagaaaacc agttcaagta
     1081 gatcctcccg tactaaaaac cattcgggat cttagttatg caaaagatat tcctatgtat
     1141 gaaatagtca aacttgcaat ggacgcctat gttgatactt taaacgacga ggaacggatt
     1201 atatataata gacgatcaaa agattaaaat ata
//
LOCUS       DAFLWQ010000224         1232 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.233, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000224 DAFLWQ010000000
VERSION     DAFLWQ010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.233"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            25..435
                     /gene="spx"
                     /locus_tag="L1V16_003097"
     CDS             25..435
                     /gene="spx"
                     /locus_tag="L1V16_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBN1277354.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            449..805
                     /locus_tag="L1V16_003098"
     CDS             449..805
                     /locus_tag="L1V16_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBN1277355.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT          445 a          177 c          231 g          379 t
ORIGIN      
        1 ttataattaa aaaggagtga gaaaatgata aaagtatata cttcgcctag ctgtacttcc
       61 tgtagaaaag caagagcatg gttgcaagcg aatcaacttg aatttgaaga gaagaatatt
      121 tttgccgaac cgttaacaga aagtgagatc aaaaagatct tggcagcgac tgaaggagga
      181 gttcaagata ttatttccac tcggtcgaaa atttacgaaa agctgggcat agattttaac
      241 gaattaactt taaagcaaat gatcgtctta ttcaaagaat atccttcatt attgagacga
      301 cctattttga ttgatgaaaa aagaatacta atcggattta atgaagatga gatccggtca
      361 tttgtccctc gtgaaattcg atgtgttgcc agaaatctga tctatttaca aaacaataac
      421 atcttaaatt catagggagg gagccttcgt ggaagtgaaa gtctatggat cagcgcactg
      481 tgtaacaagt ctgaaggcga aacaatggtt agaacaccat caattgcctt atcaatttgt
      541 tgacttagaa gaacgcgatt taagtacaga agaagcagaa gaattatgca gttttgaaga
      601 agtgcaagca gaacagctat ttgcgacttg gtctgaggct tttcacaaca ttgcgattga
      661 cctttcctgt gtaggaaaaa aacaactgat ttttttatgc acacaacata ccaatctcct
      721 cagacgtcct ttgattatta tcgatgaagt tctatttatt ggatacaatg agcagttgat
      781 ggaacagctt atcttaaata aatagacttt aactgtttta atcaagtcac tgagcatttc
      841 atacagttgt aacagtcgaa cacttagcat caagcgtgtt atgtgttctt tttttgactt
      901 tatttttcta ctatagagac atgctcaatt tatgtggtca aaattcaaat ctaggtgggg
      961 atatagagtt aaaaatatat tgacatgtgt aaatttacat gatatattca tttctgttgt
     1021 tttaagtagc aaagcaataa aatagtattt taaaaaacat ataaaatagt tgttgacatg
     1081 ttagaaatga catgataaga taactgagtt gttaaaaaag aaccacttgt gaagcttgat
     1141 tctatcgaaa aaaacttcaa aaaagttctt gacaaataac aaatgataag ttatgataaa
     1201 tgagttgctg taagatttcg aaaaacgaaa tc
//
LOCUS       DAFLWQ010000225         1214 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.234, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000225 DAFLWQ010000000
VERSION     DAFLWQ010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1214
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.234"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..747)
                     /locus_tag="L1V16_003099"
     CDS             complement(<1..747)
                     /locus_tag="L1V16_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1277356.1"
                     /translation="MFVGNFFFFLLFYMTNTDLNKRKYLFVCLLIPLTFFVELFTDVS
                     AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMFSFEGIKGYGY
                     VVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGLFVSYVAHQYQ
                     VFDHFVFGVLIFLIIQMFVVLFLFIRITIRQREQYEQQLKRKELVYLKKYTDSLEKDQ
                     EKFARFRHDYKNLLLSLKEIANQNHDSILEK"
     gene            complement(823..969)
                     /locus_tag="L1V16_003100"
     CDS             complement(823..969)
                     /locus_tag="L1V16_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HBN1277357.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFSLF
                     KKCN"
     gene            complement(1073..>1214)
                     /locus_tag="L1V16_003101"
     CDS             complement(1073..>1214)
                     /locus_tag="L1V16_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBN1277358.1"
                     /translation="LYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKS
                     QF"
BASE COUNT          456 a          191 c          128 g          439 t
ORIGIN      
        1 tttttccaat atcgaatcat ggttttgatt agcgatttct tttaaactca gcaataaatt
       61 tttatagtca tgtctaaatc tggcaaattt ttcttgatct ttttccagtg aatcagtata
      121 tttttttaga taaaccaatt cttttctttt caattgctgt tcatattgtt ctcgttgcct
      181 aatagttatt ctaataaata aaaatagaac aacaaacatt tgaatgatta aaaatattaa
      241 gacaccaaac acaaaatgat caaatacttg atattgatga gcaacataag aaacaaataa
      301 accaattgta agtaaataaa tcatgaatat agcagtaagt ttagaactgg actgttcaac
      361 aatcctattt atagctaatt ttctatataa ccaaataaac atcagcaaaa acaaagaatc
      421 aagcattatc tggaatacta cataaccata cccttttatc ccttcaaatg aaaacatata
      481 cgtcataacc atggaagtaa taatagatct gaaatcatca ataagcatac ataatagtaa
      541 tttatttaaa agcactatat tagttttctt cttttccttt aatataaaat aacttccgat
      601 tataggtata gctgcggaaa catcagtaaa taattcaaca aaaaaagtga gtggtatcaa
      661 taaacataca aaaagatatt ttcttttgtt aagatcagta ttagtcatat aaaataagag
      721 aaaaaagaaa aagtttccca cgaacattct taatagataa gcttttgtat cgatagtaat
      781 caagagatcc cctcctgatt ttaggatatc ataaaaaaaa ttttagttac actttttaaa
      841 taatgaaaaa acacattcca ctaaatttga tgccggtttt ccttgaggtt ttgttccagc
      901 acctccttta atttttttaa gctcttgatc tgaacattgt ttagcattta gtctattttt
      961 ttcttccatt acgattcccc ctacaaacta taaatacttt tatgtcactg attcaatata
     1021 cctatttttc taatcaaaaa attttgagac atatttaata ttataagtat cattaaaatt
     1081 gagatttatc tccataatct gctcgatata aaccatttat tccagcagtt cttccaattt
     1141 cactcaaatt tcttattaat tcctcttgat attcagtgaa tcttatttta ttagtataag
     1201 cagtaaaata taga
//
LOCUS       DAFLWQ010000226         1209 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.235, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000226 DAFLWQ010000000
VERSION     DAFLWQ010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1209
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.235"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..>1209
                     /locus_tag="L1V16_003102"
     CDS             <1..>1209
                     /locus_tag="L1V16_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBN1277359.1"
                     /translation="LSTTEYGTYDLTISTATLLFPILTLNIVDAVMRFLMDKDKNKKN
                     IASIAIKVIFLSVIVFGSVMYLLNITKLWQDVYGLEKYIFLYYISYVWNQFLIQFAKG
                     LEKVKAMGIAGIISTIVTIIANIFFLLILKWGLIGFFIANILSQIISATYLSVLVRIW
                     EYIDFEAKDPQLKREMLNYSIPLIATVVGWWINSTADRYVVSFIVGVSANGLLSVAYK
                     IPQIINTLQGIFIQAWQISAIKEYGDNETAKFYGNTFVMINLLMCITCSSLIILTRPF
                     SHILYAKDFYEAWKYVPFLLIANVLNCASGLLGPILSAKKDSKSMMWSAIIGALVNVI
                     MSVVLVYKIGVQGATIATVICSYVIYVVRKRAVGKDIFIKHYHIVVESWGLLFVQAII
                     EIYFKNYVIEI"
BASE COUNT          400 a          146 c          219 g          444 t
ORIGIN      
        1 ttatccacaa cagaatatgg cacatatgat ttgacaattt caacagccac attattgttt
       61 ccaattttaa ccttaaacat tgtagatgct gtgatgcgct ttttaatgga taaagataaa
      121 aataaaaaaa atatagcatc tatagcgatt aaagttatat ttttaagcgt gatagtcttt
      181 ggatccgtaa tgtatttgtt aaatattaca aaattatggc aagatgttta tggattagaa
      241 aaatatattt ttttgtatta tatatcctat gtatggaatc aatttctaat acaatttgct
      301 aaagggttag aaaaagttaa agctatgggc atagcaggta ttatcagcac aattgtaaca
      361 ataattgcca atattttctt cttgcttatt ctgaaatggg gattaattgg ttttttcatt
      421 gcaaatattt tatcacagat tatttcagct acttatctgt cagtattagt gagaatatgg
      481 gaatatatcg attttgaggc taaagatcct cagctaaaga gagaaatgct aaattactcg
      541 attccattaa ttgcaactgt tgttggatgg tggattaata gtacagctga taggtatgtg
      601 gtttccttta tagtaggtgt ctcggcgaat ggcttattgt ctgtggcata taaaatacct
      661 caaataatta atactttgca gggaatattt atacaggcct ggcaaatttc tgcaattaaa
      721 gaatatggag ataatgagac tgcaaaattt tatggaaata catttgttat gattaatttg
      781 ttaatgtgca taacctgttc aagtcttatc atattaacta gaccgttttc acatattctt
      841 tatgcgaaag acttttatga agcgtggaaa tatgttccat ttttattaat agctaatgtt
      901 ttaaattgtg catcaggtct gttaggacct atcttatcag caaaaaaaga ttctaaatcc
      961 atgatgtggt ctgcaatcat aggggcatta gttaatgtga ttatgagtgt agtccttgtt
     1021 tataagatag gggttcaagg tgccacaata gccactgtta tatgttcata tgtaatatat
     1081 gttgttcgta aacgagctgt gggaaaagat atttttataa agcattatca tattgttgtg
     1141 gaatcttggg gattattgtt tgttcaggca atcatagaaa tatattttaa aaattatgta
     1201 atagaaatt
//
LOCUS       DAFLWQ010000227         1199 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.236, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000227 DAFLWQ010000000
VERSION     DAFLWQ010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.236"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            52..>1199
                     /locus_tag="L1V16_003103"
     CDS             52..>1199
                     /locus_tag="L1V16_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBN1277360.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNA"
BASE COUNT          366 a          235 c          238 g          360 t
ORIGIN      
        1 cctgaaatcc tttagaatta atttggctac caattcatag gaggattcaa gatgtctcat
       61 actcagctta tcaaagatac cctaaatatt ctagacctaa atatctattt cgaggaaaat
      121 tgtttaacta aagaaaaata caaagggcaa atttgcttga tttacaaagg aactcttctg
      181 tacaagccag aagagtgttc ccattgtctt tgtgtcgtcc cctctaggat cattcgttgg
      241 gggacgacaa ccgttcggtt gttactgaat gatgtgtctg agtatcgcac ttatctggag
      301 ctgaagaaac aacgatttaa atgtaagtct tgccaaagaa cattcgtagc ggatacctct
      361 gttgctgaaa aacactgttt cattagtcaa aaagttcgtt ggtctgtcat tgctcgctta
      421 aaagagaata cttccatgac ggaaatcgct cgtcagaaaa atatttccac ttcttcggtc
      481 tatcgtgtca tgaagcgatt ctaccgccca ttgaatcctt tcaaacagac tttgccaaag
      541 gtcttatgct ttgatgaatt caaatcggtt cgaagtgttg ccagtgcaat gagttttatc
      601 atgatggacg gacaaagcca tgcattattg gatattgtcg aaaatcgacg cttgccttat
      661 ttagaacgct atttttctcg gttttcatta gcgactcgtg aagccgttca attgattgtt
      721 attgatatgt atgcgcctta tgtttcgttg gtgaaaaagc ttttcccgaa tgctcagttg
      781 atcatcgatc gtttccacat cgtccaacat attggcagaa ctttcttgaa tcatcgagtg
      841 aaagaaacca cggtacgact taaaggaaat tcccactctc aacgagggtt agggaaaaaa
      901 ttgaagcgct attggaaact cctacaaaaa gaagaagcaa agttaaacta tgaaaaacgg
      961 gtttggcgtg ccagttttaa agattatttg actgaaagtg agattgccga tcgactgtta
     1021 gctgcttgtc ccaacttacg ccaaggctat cagttatacc aagacattct ttatgcggta
     1081 aagaaaagag atcagtcact atttgaggat tgtttaacta gagacattag cggtctgcca
     1141 gaaacctata caaccacttt acgaacgttt aaaaagtttc tgccacagat ccaaaatgc
//
LOCUS       DAFLWQ010000228         1183 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.237, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000228 DAFLWQ010000000
VERSION     DAFLWQ010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1183
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.237"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..563)
                     /locus_tag="L1V16_003104"
     CDS             complement(<1..563)
                     /locus_tag="L1V16_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBN1277361.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGPNEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLA"
     gene            complement(574..771)
                     /locus_tag="L1V16_003105"
     CDS             complement(574..771)
                     /locus_tag="L1V16_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBN1277362.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            complement(794..1087)
                     /locus_tag="L1V16_003106"
     CDS             complement(794..1087)
                     /locus_tag="L1V16_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277363.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIRPVTASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERSR"
BASE COUNT          326 a          238 c          191 g          428 t
ORIGIN      
        1 gctaattttt ctttacttac gcccatttca gaaagataac cgtaaggatc tgtatgatcg
       61 ccccagatgt tttgtgttac ccataaatgc gatttgattc ccggttggtt ataaggagtg
      121 tccaacgtta atggaatacc atatttcatt gctgaatctc tagccaattc aacgtatgcc
      181 ttgtagtttt tctcaaacgt tgctttatca tgtgtgtgtt gtaactcaat ctgcacagga
      241 ctgttggcat tagcatacga accagcaccg tactgtacat aaccaggttg accgacttga
      301 taaacaattc cgccgtctcc cacaatataa gcagtataag cgctagtcca tgaacgttgc
      361 atatactgcg cttcattgcg tcctgttgct gtttcattag ccgtttcatg cagtaaaatg
      421 tactgattat ttgctacttg tgagctacct tcgtttgggc ctaaattaaa ttcattgtta
      481 atcgtatagg caaacccatt aattggcaat aaaaaaagag ccgttaatag gctcatcgca
      541 gtaatagtaa ttttcttttt catttgtttc ctcctatttt ttcaaattat aagccgacac
      601 gccagtgata acgcctaaaa atgttgctac tgcattgata gtgagtactg tcatatctgt
      661 tccattccat ccatacgctt tgcctagtgt tgcaactaat acagatgcag ctggcaatac
      721 tgttaaaact gtccatttaa tgacttgata atacttatcg ggtaaaatca tttcttctta
      781 actcctttct tttttaccga gatctttctc taaataaagt tttgatttgt tgtgtgtgtt
      841 ctaccaattt ttctgtatgt gtatctaatc tttcatcgtg tttctttagt tcttcatgaa
      901 tcatcaatcg atctgatttg ctcgattcta aatctttagt cagcaaatct aaattgtgac
      961 ttacttttga aagagtttca gtaatcttcg agaaagatgc agtgactggt cttattacta
     1021 ataaaatcaa agaaacaatc gcagtgattg atcctgcgat tgttccccat tctcctaaat
     1081 taatcatgtg acaactcctt taccttaaat aaaaacgcat caattaagat gcgctcttat
     1141 ctttattaat gattttatct gcttcttcgt ctgtaatgca taa
//
LOCUS       DAFLWQ010000229         1177 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.238, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000229 DAFLWQ010000000
VERSION     DAFLWQ010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1177
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.238"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            98..391
                     /locus_tag="L1V16_003107"
     CDS             98..391
                     /locus_tag="L1V16_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277364.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            388..612
                     /locus_tag="L1V16_003108"
     CDS             388..612
                     /locus_tag="L1V16_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBN1277365.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            609..>1177
                     /locus_tag="L1V16_003109"
     CDS             609..>1177
                     /locus_tag="L1V16_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1277366.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLA"
BASE COUNT          406 a          180 c          248 g          343 t
ORIGIN      
        1 ttgtgcatta ctgaagaaga agcagataaa atcattagca aagaagagag cgcatcttaa
       61 ttgatgtgct ttttattttg attcaaggag ttgtcacatg attaatttag gggaatgggg
      121 agcgatagca ggatcaataa ccgctatcgt ttctttgatt ttattagtaa taaaaccaat
      181 tactgcatct ttctcgaaga ttactgagac tctttcaaaa gtaagtcaca atttagattt
      241 gctgactaaa gatttagaat cgagcaaatc agatcgattg atgattcatg aagaactaaa
      301 gaaacacgat gaaagattag atacacatac agaaaaattg gtggaacaca cgcaacaaat
      361 taaaacttta tttagggaga gaagaaaatg aataataaaa cgttcgaagt actaaaatgg
      421 ttcgcactgg taattattcc cgcactagct actttcgtgg ggttagttgg taaagcgctc
      481 aattggcagt acacagatat ctgtgttgtc atcattactg gttttggcgc gtttttaggg
      541 agtgtgttgg gtgtatcaaa tcgaacctac aaaatgttct cggctgaaag cgaagaagga
      601 ggaaacaaat gaaaaagaaa attactatta ctgcgatgag cctgttaacg gctctttttt
      661 tattacccat taatacgttt gcttatacta ttaatgacga gtataattta gcgccgaatc
      721 aaggagactc cagattagca attcctaaca aaattatttt gcacgaaact ggaatagatg
      781 caccagcaag aaacgtagcc gccaacatga aaaataatta taacggaagc aattcttata
      841 ctacagatgt tattggtgac ggtgggattg tttaccgtgt gggtgagcaa ggatatgttt
      901 cgtggggagc tggtaacgct aatccttatg cgcctgtaca gattgaatta cagcgcacat
      961 atgataaagc attgtttgaa aaaaactatc gagcttatat tgaatataca agagatagtg
     1021 caaaaaaata tggaattcca ttgactcttg atcaaggaac ttctttattt acaaaaggaa
     1081 tcatttctca tttgtgggtg acaaattatg tttgggggaa ccacacagat ccatatggtt
     1141 acttatcgca aatgggagtt agcaaagaaa agcttgc
//
LOCUS       DAFLWQ010000230         1173 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.239, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000230 DAFLWQ010000000
VERSION     DAFLWQ010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.239"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..763
                     /locus_tag="L1V16_003110"
     CDS             <1..763
                     /locus_tag="L1V16_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBN1277367.1"
                     /translation="EKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKIT
                     EEKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKE
                     LYANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLE
                     PMDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSL
                     DEIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            835..>1173
                     /locus_tag="L1V16_003111"
     CDS             835..>1173
                     /locus_tag="L1V16_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277368.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLI"
BASE COUNT          518 a          133 c          193 g          329 t
ORIGIN      
        1 ggaaaaaatc ataaaaatat ttgataaaat taataattta ttcaagaatg acaatgctga
       61 attaaggaag ggtcttttag agtttaaact tcaagaacta gaacttcatt actcttattt
      121 agtgaaaatt accgaagaaa aagaacaaca aaaagcaata aaagaacaga tgatagaaga
      181 ggaaaaagtt cgtagagaaa ttgatcgtga aaagaaacgt attgataaag aacaacgtca
      241 attcaattct gaaatttcca aattaatcgc atatatgcaa aaagctaatg cagatgtgga
      301 aaaagaatta tatgcaaata aaattcaaga actggaagaa aaattaaaag aattagaagt
      361 tatacgtgaa aatgtattac aaagagaatt aaatactaga gccggttatg tgtatgtaat
      421 tagtaatatt gggtcttttg gtgaagacat atataaaatt ggtatgacta gaagattaga
      481 acctatggat agaataaaag aattgagtag tgcatcggtt ccatttgaat ttgacgttca
      541 tgcgatgatt ttttcagagg acgctccgtc tttggaaact aaattgcata atcattttag
      601 aaaacaagaa gttaataaaa ttaatcaaag aaaagaattt ttcaaagttt cactagacga
      661 aatagagaaa gttgttttag aaaattataa tggaacagta acatttacaa aattagctaa
      721 agctgaacaa tatagacgat ctttagaatt gtcaaaagat taaatatata aaaagccttc
      781 gggctttttc ttttaacaat taataggaac gtatattcga aaggaataga aataatgtgg
      841 ttagaaaaaa taaatgacaa aaaatttaag tacaccgaac gttatacgga tcccttaact
      901 gaaaaaaaga gaaaagtgtc cgttacttta tctagcaatt cacgccaagc ttggaatcaa
      961 gctaacttac ttttgaatga aaaaatcgca gaaaaaataa aacgaaatga agaattacca
     1021 ctaacttttg gagaattaaa aactaaatgg gatgaaaaat acaagccaac tgtaaaagaa
     1081 agttcctatc gaacaactca ggtttatcta tcattaattt caaaatatat aaaagatgat
     1141 gtacttgtaa aaaacgttaa tagtaatctt ata
//
LOCUS       DAFLWQ010000231         1137 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.240, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000231 DAFLWQ010000000
VERSION     DAFLWQ010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1137
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.240"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..355
                     /locus_tag="L1V16_003112"
     CDS             <1..355
                     /locus_tag="L1V16_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277369.1"
                     /translation="GAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETNMTRDELL
                     RKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTTSQIKQDT
                     EDSLRKGWGMNNKVR"
     gene            615..910
                     /locus_tag="L1V16_003113"
                     /pseudo
     CDS             615..910
                     /locus_tag="L1V16_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            985..>1137
                     /locus_tag="L1V16_003114"
     CDS             985..>1137
                     /locus_tag="L1V16_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBN1277370.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWV"
BASE COUNT          431 a          135 c          237 g          334 t
ORIGIN      
        1 tggcgcacca atcagaaagt ttgataaggt ttattccacc aagcatcctt taaaactgtc
       61 gactttgtta aatgcgactt ccagagtttt agtagaaaag tatgagacta atatgacaag
      121 agatgaattg cttagaaaag ctttagatga gtatattaaa cagaatctta cgcaagaaga
      181 taagcaagat ttgtttaatg acgtggtgaa agaactagac ttgttcagag aaaaatatcc
      241 aattgttcca gaattagatg atcgtggaga aataataaga actaccagtc agataaaaca
      301 agataccgaa gactcactgc gcaaagggtg gggaatgaat aataaagtta gataataatc
      361 aaagaagaac taagtaacta cctttaaacg gtagttactt agttcttctt tgatttgcat
      421 gaaatagagg ggatttattt ttctggttac gtgattaaaa aatccaaaaa atgagcatag
      481 gaacggttat gattttaggg tgtgttttaa tgagatattg tgatttcatt aacaagtgta
      541 tgataatctg ttgttgagtt agtaaataag taatagagct aactctaaaa taaaactatt
      601 aggaggagat gtaggtgaaa aagtttaaaa agaaaatata tttaggattg gttgttgggg
      661 tgagtatgtt tgggttcatg gctcatacta aacaagtaac tgcagatact aaccaaaaag
      721 aaaggattat gagccaatta gatgactctc aaataagtat gtacccaatg agctaattgt
      781 cagtttaaag gctacacaaa gaatttcaac agagaaaaat aaaccgcaaa atttattggg
      841 tgtaaaagtt atggtggaaa aagatttgac tcttaggaca aatgaaagcg attgtaataa
      901 gcgagatcaa gggttctgtt gcaaagtttt ccaaaaaatc tattttagtg taaaattgag
      961 aaaaaagaca gagaggacag agtaatgaat cattttaaag gcaaacaatt caaaaaagac
     1021 gtcattattg tcgctgttgg ttactacctg cgttacaatc taagctatcg tgaagttcag
     1081 gaattgttat atgatcgtgg aataaatgtt tgtcatacta cgatttatcg ttgggta
//
LOCUS       DAFLWQ010000232         1092 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.241, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000232 DAFLWQ010000000
VERSION     DAFLWQ010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1092
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.241"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(37..>1092)
                     /locus_tag="L1V16_003115"
     CDS             complement(37..>1092)
                     /locus_tag="L1V16_003115"
                     /inference="COORDINATES: protein motif:HMM:NF014051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBN1277371.1"
                     /translation="FVGLEKIKNVVFRNMFVKVCTIFLIFLLIKNKNDLSIYIIIISL
                     GSLVGNFIFFFSLKKYLDFDKIVGLDLSNLRPFINSIVILLVPQVAIQLYQYIIKFSI
                     ENSTTTTELSYFDQSQKIARIIIQLVSSISIVLMPVIANLDKNKSRNALNKIIQLSVN
                     YSLSIAVIFTILLVIISPTFVPIFFGPEFKEMIPHMIISSFIIIPICVGGVFSNQLIL
                     GMGLYKYYATPYLIGGSIGILICLIYKDKMSGLIGCIVLVIVESLVCFFRIIFANKII
                     DIKENLQGTIKEFFLLFLLLAEVYIVNTIFTPSPSALLNLFYMMIIIIQYFVLSTIIK
                     TETAKDLSKRLKSFLIK"
BASE COUNT          428 a          148 c          129 g          387 t
ORIGIN      
        1 cataaacttc tattccagat ttagtttggt aaagtgttat ttaattaaaa atgattttaa
       61 ccgttttgat aaatctttcg cagtctctgt ttttattata gtacttaaaa caaagtattg
      121 tataattatg atcatcatat aaaataaatt taataacgct gatgggcttg gcgtaaatat
      181 ggtatttaca atgtatactt cagctaataa taagaataat aagaagaatt cctttattgt
      241 cccttgtaaa ttttctttta tatctattat tttatttgca aatattattc taaaaaagca
      301 aacaagtgat tctactataa ctagtactat acatccaatt aatccactca ttttgtcttt
      361 ataaattaag caaattaaaa ttcctatact tccacctata agatatggtg tagcataata
      421 tttatacaac cccatcccta aaatgagctg gttagaaaag actccaccta cacaaattgg
      481 aattataata aaagatgaga ttatcatatg aggtatcatt tctttaaatt caggaccaaa
      541 aaaaattgga acgaaagtgg gtgaaattat tacaagcaaa attgtaaata tcaccgctat
      601 acttaatgaa taatttaccg acaactgaat aattttattc agagcatttc tggatttatt
      661 tttatctaga tttgcaatga ctggcattaa tacaatacta attgaactaa ctaattgaat
      721 gattattcta gcaatttttt gagattgatc aaaataagat aactcagtag tcgtagtaga
      781 attttcaata ctaaatttta ttatatactg atatagctga atagccactt gaggaacaag
      841 caatattaca attgaattaa taaatggcct taagttagat aaatctaaac cgacaatctt
      901 gtcgaaatcg agatattttt ttaaggagaa gaaaaatata aaattaccaa ctaacgatcc
      961 caaagaaata ataatgatgt atatagaaag atcattttta ttttttatca atagaaaaat
     1021 caaaaaaatt gtacatacct ttacgaacat atttctaaat acaacatttt ttattttttc
     1081 taatccgaca aa
//
LOCUS       DAFLWQ010000233         1090 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.242, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000233 DAFLWQ010000000
VERSION     DAFLWQ010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1090
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.242"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            4..978
                     /gene="bsh"
                     /locus_tag="L1V16_003116"
     CDS             4..978
                     /gene="bsh"
                     /locus_tag="L1V16_003116"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBN1277372.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          382 a          136 c          187 g          385 t
ORIGIN      
        1 actatgtgta cgtctattac ttatgtaaca agtgatcatt attttggaag gaattttgat
       61 tatgaaatat cttacaatga agtagttact gttactccaa gaaattataa gttgaatttt
      121 cgaaaggtaa atgatttgga tactcattat gcaatgattg gtattgccgc tggtatagct
      181 gactaccctc tttattacga tgcgacaaat gaaaaaggat tgagtatggc tgggctaaat
      241 ttttctgggt atgctgatta taaagaaata caagaaggga aagacaatgt atctcctttt
      301 gaatttattc cttggatttt aggacaatgc tcaacagtag gagaaactaa aaaattgtta
      361 aaaaatatca atttagcaaa tataaattat agtgatgaac ttcctttatc ccctttacat
      421 tggctattag ctgataaaga aaaatcaatt gtcattgaaa gtatgaaaga tggacttcat
      481 atatatgata accctgtggg cgttcttacc aataatcctt catttgacta tcaattattt
      541 aatttaaaca attatcgtgt cttatcgagt gaaactccta aaaataattt ttcaaatcaa
      601 ataagtttga atgcctatag ccgcggtatg ggagggatag gcttgcctgg agatttatcc
      661 tcagtatctc gttttgttaa agcgactttt acgaagctga attctgtatc tggagattca
      721 gagtcagaaa gtattagtca atttttccat atcttaggtt cagtagaaca acaaaaaggt
      781 ttgtgtgatg ttggtgatgg aaaatatgaa tatacaattt attcttcttg ttgcaatgtt
      841 gacaaaggaa tctattatta tcgaacatat gaagacagtc aaattactgc aattgatatg
      901 aataaagaag acttagatag tcataagtta attagttatc caattataga aaaacaacaa
      961 attaaatata taaattagtt aatgtgttgt gattgattat ttaatataga tataatacaa
     1021 aaaggcaaag atattttcaa aacatttttt cttgatgtga tatccttgtc ttttttgtaa
     1081 tgtttttaac
//
LOCUS       DAFLWQ010000234         1074 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.243, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000234 DAFLWQ010000000
VERSION     DAFLWQ010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1074
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.243"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     misc_binding    complement(19..253)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            343..828
                     /locus_tag="L1V16_003117"
     CDS             343..828
                     /locus_tag="L1V16_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBN1277373.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
BASE COUNT          341 a          224 c          169 g          340 t
ORIGIN      
        1 agtcctttga tccgaagatc aaaggacgtt aatcacgtgg ttccaccttt ttttaccgac
       61 tcctcacgga aaagccagcc ttatctggtc atctagcaac gaccgcagct gtaacgggct
      121 ccccggattt tcctactata cgcttcagaa aatcgactcc aagatgtgtt tcacggttaa
      181 ctgctgcctc tttccaccaa ccagagactc tctaaaaaca cctaacggct actcttcttt
      241 tcgatgtcat ttgttttaac tttacgtgta atttacatga ttatttttca tttgtcaact
      301 cttttttatg atacactaat aaaaaaagga gggtgatgcg cgatgagtcg tgcaaccgaa
      361 caagaagctt atgaactact aaaaaaactg ggtatctctt ttcaaaaagt cgatcatcct
      421 gcgattacgt cagtcaaaaa tgtccctttt tccctacctg gtccgcaagt aaaaaatcta
      481 ttattgaaat caagaaaagg aaaacaaatc tatcttgtca tcttgcctga tgaaaagcac
      541 gccgatttaa aacaactagc tgaacaatta aaagaaaagc gcttatcttt tgtttctgaa
      601 gaacagcttc ctgacctcct aggcgttcca gcaggtacag tgactccatt agcattgatg
      661 cacgacaaag agaaaaaaat ccaagtcgtg atcgatgctg ctattgatcg tcaagatacc
      721 gtaggctttc atccaaatat caataccact acgttgatta tggatttttc cgactttgaa
      781 aagatacttg tttacttaga acatctgcca gtttatgaaa atttgtaatg atagagtagt
      841 tttcttattt cccaattcaa gcgtcttttt ctttatttag cacaaaatat atcagaaatt
      901 cttttggcca atcaaacaat gtaacaacta gtatgaacgc tgaaaactaa tacgagtatt
      961 cttccatagt tagccaaatc catatttatt gattctacga aaaaagaagc atatataaaa
     1021 atgcttcttt tttcgattat aaatcggaat tttattcttt tgatttcagt cata
//
LOCUS       DAFLWQ010000235         1071 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.244, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000235 DAFLWQ010000000
VERSION     DAFLWQ010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1071
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.244"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(61..>1071)
                     /locus_tag="L1V16_003118"
     CDS             complement(61..>1071)
                     /locus_tag="L1V16_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1277374.1"
                     /translation="ELEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYE
                     DTLMNIKKYMPAVLISDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGL
                     IPFDPTRKAVIKGKDSLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATG
                     MRFAELLGLTWEDIDFEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKK
                     FKINQKELFENFEIKNPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLR
                     HTHASILLYQGVNILSVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKN
                     DN"
BASE COUNT          316 a          181 c          154 g          420 t
ORIGIN      
        1 acccctgtat cctttgcggt acaggggttt gttttgtatt tgtgccaaaa atgtgccaaa
       61 ctagttatca tttttatata aactatcgaa cacagtattg attttttctt tatcctgatc
      121 ttcaagctct cgaacaatat gaagataagt agacattgta gtttctaaac tgctatgtcc
      181 taaacgtttc gatacgctaa gtatatttac tccttgataa agtaaaatag atgcatgtgt
      241 atgccttagt ccatgcaaag taaattgctt ttcaatccct aattctttta attttttgcg
      301 caaatatttg ctgacggcgt ttgatgaaac taatccattt tttaagttga aaaaaacaaa
      361 attatgaggg tttttgattt caaaattctc gaataattct ttttgattga ttttaaactt
      421 ttttaagaga tcaatcgtat gtttatcaat ggaaattttc ctatttgaag tttcgttttt
      481 tgtttttccc cattcattta atttataatt ccatgtttta ttaatagtga tgatttgatc
      541 ttcgaaatcg atatcttccc atgttaatcc tagaagttca gcaaatcgca ttccagtggc
      601 accagcaact aacacgagca taggagaaga gtactgcgca gaaaggtttt cttctacgag
      661 tttcattaaa gatttaaatt gatcataatc taaatattta tcttcttttg gcttcaatga
      721 atcttttcct ttgattactg cttttctagt tggatcaaac ggaattaatc cttcttctac
      781 ggcatctttc aacgacgctc taatatggtt attaaactta ataacggtag attttacatg
      841 gtctttagca tacttattta aaaagcgttg atatcccact ctatctaaat cagaaatcaa
      901 taccgctggc atatatttct ttatgttcat taacgtatct tcgtattttc tataagtgat
      961 aggagatact gttccttctt tataaagttg catccaatcc tcaaagtaat ctgataataa
     1021 tagatttttg cgatcccctt taaggccttt gttcaagtta tattctaatt c
//
LOCUS       DAFLWQ010000236         1061 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.245, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000236 DAFLWQ010000000
VERSION     DAFLWQ010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1061
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.245"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(36..992)
                     /locus_tag="L1V16_003119"
     CDS             complement(36..992)
                     /locus_tag="L1V16_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277375.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgtca a
//
LOCUS       DAFLWQ010000237         1045 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.246, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000237 DAFLWQ010000000
VERSION     DAFLWQ010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.246"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..977
                     /locus_tag="L1V16_003120"
     CDS             <1..977
                     /locus_tag="L1V16_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277376.1"
                     /translation="KNTKEIAKKIEEKKVFDGCHYLESKSFDDNIGYFQKIKDCLQIS
                     CGKSNRYAYYLKNCKSEYFDEFICFSMGEVWLEGIYACLYRNNKNVQVSILEEGILSY
                     GVDIIPTARTKAIAVLNYLKKRTPLYNKSYNFYCFFPNIYTGRENTIQIPLVTAGSRT
                     ALQLSDIFNPMIDIYKEKKYIFFTSVYDFEGGEPVGEYELVCKIADLVGKDNLIVKTH
                     PRDVRTIYKDNGFIEDKNSSIPWEAIQLSGDFNDKIFMTINSGSVISGSTMSAKPVRT
                     YYMYKLCNIEGNPSCKKNAYDIERLLKQKTMKNILKNVKIAESLDDIL"
BASE COUNT          414 a          117 c          182 g          332 t
ORIGIN      
        1 ctaaaaacac taaagaaatt gcgaaaaaaa tagaagaaaa aaaagtgttt gatggctgtc
       61 attatttaga aagcaaatct tttgatgata atattgggta ttttcaaaag attaaggact
      121 gtcttcagat ttcttgtggt aaatcaaatc gatatgccta ttatttgaaa aactgtaaaa
      181 gtgaatattt tgatgaattt atttgttttt caatgggaga ggtttggttg gaaggaatat
      241 atgcttgctt atatcgaaat aataaaaatg tacaggtatc aattttagaa gaaggtattt
      301 taagctatgg agttgacatt attccaacag caagaacaaa agctatcgca gtactcaatt
      361 acttaaaaaa aaggactcca ctatataaca aaagctataa tttttattgt ttttttccta
      421 atatatatac aggaagagag aatacaatac aaattccatt agttacagct gggtcaagaa
      481 ccgcattgca actttcggat atttttaacc ctatgataga tatttataaa gaaaaaaaat
      541 atatattttt tacgtctgtt tatgattttg agggcggaga acctgtcgga gaatatgaat
      601 tagtatgcaa aatagcagac ttagtaggaa aagataatct aattgttaag acgcatccta
      661 gagatgtaag aacaatttat aaagataatg gatttatcga ggataaaaat tcatcaatac
      721 cttgggaggc gattcaattg tcaggcgatt ttaacgataa aatatttatg acaattaatt
      781 caggaagtgt tatttcaggt agtacaatgt ctgcaaaacc tgtacgcacg tattatatgt
      841 ataaattgtg taacatagaa ggaaatccgt cttgcaaaaa gaatgcgtat gatattgagc
      901 gattgcttaa gcaaaaaacg atgaaaaaca ttttaaagaa tgtgaaaata gcagaaagct
      961 tagatgatat actatgagca aaactaaata tttaattaaa aatatgggaa tattaacaat
     1021 aagtaatttt tcttcaaaaa tttta
//
LOCUS       DAFLWQ010000238         1003 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.247, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000238 DAFLWQ010000000
VERSION     DAFLWQ010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.247"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            370..1003
                     /locus_tag="L1V16_003121"
                     /pseudo
     CDS             370..1003
                     /locus_tag="L1V16_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          182 c          184 g          295 t
ORIGIN      
        1 gtttcaaagt tagtagagaa aatgtagtta tatatttaaa tttttaccag aaagaaatga
       61 acaccttcaa ttatctaaat ctcgaaaatg gttagatgta atcatcagga aaaacaatct
      121 taaacgaatt actattcatg gtcttagaca cacacatgct agcttgcttt tagcaagcta
      181 gtgcaaatat taaagatgtg caagagcgtt taggccactc ttctattcaa atcattatgg
      241 atctatatat tcatattaca gacaaaagaa aagaagaaac cgtagcgcaa ttcgcaaaat
      301 ataggctcta taatttatgg gactgatgaa tcaaaattga ttcttcagtc ccattgttat
      361 tttaggtata tgattcgtac attgaaagag ttgaaaaact atcttccgaa gccgtcaaaa
      421 aggaccctgc caaaagtatt gatggtggat gaatttcgtt cgcacgcttc aattgtggat
      481 aaaatgagct ttatttgtgc ggatggcgag actggaaaac tcattgatat tttgcctaca
      541 cgaaaattgt ctcgattaac acactatttt agtcgctgtg caaatcctga agcggtggaa
      601 tatttagtga cagatatgaa cgccgcctac ttccaactga caaaacgtgt cttaccaaat
      661 gcgaaagtcg tcattgattg ttttcatatc atcaaacatt tgaatcaggc gttcaatgat
      721 tttcgtgtac aagaaatgaa aagattacac cagttagggc aacgacggga agccgagaaa
      781 gtgaaaaaga actggcgctt tcttctaaaa aaccgtcaaa aaatcaatca ctatgattac
      841 aaaacatggc gcagttttcg tgcacctaaa tacccgctac tcactgaagc aatgatgatt
      901 gatcgattgc tggcattttc aacgccttta aaggacgcct atactttttt ccatgagctg
      961 accgaagcct ttagagacaa ggaatcagac ttatttttta cct
//
LOCUS       DAFLWQ010000239          974 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.248, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000239 DAFLWQ010000000
VERSION     DAFLWQ010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..974
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.248"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            531..>974
                     /locus_tag="L1V16_003122"
     CDS             531..>974
                     /locus_tag="L1V16_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277377.1"
                     /translation="MSVKKMLFMVSTIIVLTSRFWGINTSLSMRYFIMAIWDLYFMLS
                     YFSYREKTYKKYVIKNNFWLTIMPFVIFSIYTLIIWGIGSNAEFENFIKLCSTLLYLI
                     LAYGYACTAFYLFKAEGIDFIFWSGVISYMSGSVFYLIVSYGLNGL"
BASE COUNT          336 a           94 c          167 g          377 t
ORIGIN      
        1 tgtggattat caccttccaa cagtatataa aatgagcgta aaaacggcta tttttgcctt
       61 aacaacgatt tttttgtata caaatacgat atgctcatta attattggaa tttgtagtgc
      121 tgtttaaatt aatgaaggtg taattatatg agtgatcatt ttgaaaaagt ttgttgagaa
      181 gatgtgcttc tagtcatgtg atgggagaaa ataatttaac tgttagagtg aatagttaaa
      241 ttattctggt tatatgaaaa aagtagtttc taaaataatc ttgcagggat taacttaaag
      301 aaattgagag aatagtttct ttgaaatttc tatatacaat gagaagctga aatttacttt
      361 tatttgatga ctggaaatag aaattaaata tattgtattg ttacattaaa gaaaacttgt
      421 atggaaaaat cagtacaata ccattattta atgttcttca cttaaagcgc aaaaaatatc
      481 agtttattaa actcgtatat agaacaaata tatgtagacg gggcgaaacg atgagtgtaa
      541 aaaaaatgct atttatggta agtacaataa ttgtattaac atcccgattt tggggaatta
      601 atactagttt atctatgcga tattttatta tggcaatatg ggatttatat tttatgttaa
      661 gctatttttc ttatcgtgag aaaacatata aaaaatacgt tatcaagaat aacttttggt
      721 tgactataat gccgtttgtg atattttcta tctatactct aataatatgg ggaattggtt
      781 caaatgcaga atttgaaaat tttataaagt tatgttccac gttgctttat ttaattcttg
      841 catatggtta cgcatgtaca gcattttact tatttaaggc agaaggaatt gattttattt
      901 tttggtcagg tgttatttca tatatgagtg gttcagtttt ttatttaatt gtatcttatg
      961 gtttaaatgg ttta
//
LOCUS       DAFLWQ010000240          959 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.249, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000240 DAFLWQ010000000
VERSION     DAFLWQ010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.249"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(107..511)
                     /locus_tag="L1V16_003123"
                     /pseudo
     CDS             complement(107..511)
                     /locus_tag="L1V16_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
     gene            complement(570..>959)
                     /locus_tag="L1V16_003124"
     CDS             complement(570..>959)
                     /locus_tag="L1V16_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1277378.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          287 a          170 c          159 g          343 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgagacacg acctaaagat cgtgtctaat
       61 tatgactgta tcagaaaata tgataccaaa cggatctatt cattaattaa ttgacatagt
      121 ttatctgttg ctcttttatg actggataac tgaccaattc atgacgatcc aagtcttctt
      181 tattcatatt tacagcagta atttgactgt cttcatacgt acgataataa taaatccctt
      241 tatcaacgtt acagcaagaa gaataaatcg tatattcgta ttttccttct ccagtatcgc
      301 atactccttt ttgttgctcg actgagccta gtatatgaaa aaattgactg atactttcag
      361 attctgaatc acctgatgca gcattcattt tagtaaatgt ggcttttaca aatcgagaaa
      421 cagaagagag atctccaggt aagcccaatc ctcccatccc acgactataa acattcaagc
      481 tgatctggtt tgaaaaatga ttttctggtg ttccattggg agcgtcaata attttgtgta
      541 aataaattgt cctcctgcaa aataattagt tactcagtaa acattgaaac taatgtatcg
      601 gttacctgtt gaaaaccttt atggcttctg tttagaaatt tttgattgta tgtatcaaaa
      661 atgctgacta gaaagcgttc tagtgattct tcattttgaa actgctcttt tctacggctg
      721 tatcttttaa tttgcttatt gaaagactcg attagattgg ttgagtaaat ggttctacga
      781 atgctaggtg gaaaatcata aaaagttaat aagtcttggt tttctatgag tgactgcgtc
      841 actttaggat agtttttctt ccatttctca atcatgccgg ataagaaggt attcgcttct
      901 tcttttgagt tagcttgata aacagcctta aagtcatcac agatttcttt tcggtcttt
//
LOCUS       DAFLWQ010000241          943 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.250, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000241 DAFLWQ010000000
VERSION     DAFLWQ010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.250"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..>943
                     /locus_tag="L1V16_003125"
     rRNA            <1..>943
                     /locus_tag="L1V16_003125"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          293 a          187 c          274 g          189 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact agg
//
LOCUS       DAFLWQ010000242          934 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.251, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000242 DAFLWQ010000000
VERSION     DAFLWQ010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..934
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.251"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            218..802
                     /locus_tag="L1V16_003126"
     CDS             218..802
                     /locus_tag="L1V16_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1277379.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT          302 a          130 c          185 g          317 t
ORIGIN      
        1 aaaataatga ttttaaaaaa agagtgtcta gtcgacattc tttttttcta attgaaagtg
       61 ttcataaaat cacccatttc tggacacttt ctttttttgc tttatttttc aaaaaaacaa
      121 ttcatttcat gttcataaac ccataacaat atctatgttc agttaaacta tatggataaa
      181 gttatgttac aataaaatta atgaaggagt gatttttttg aaaataggat acgcccgggt
      241 atctactggt ttacaaaatt tggatttaca agaagacagc ctaaataaat ttggttgtga
      301 aaaaattttt actgatcata tgagtggggc aaaaagtaat cgaccaggat tagaaatggc
      361 cattgatttt gttcgctctg gcgatacact tgtcgtttgg cgcttagatc gtttaggtag
      421 aaatatggaa gatttgattt caatcgtcaa tcgactgaat gagcgtggtg tgagttttca
      481 tagtattcaa gaaaatatta cgatggacaa atcaagttct acaggacagc tcatgtttca
      541 tttgtttgcg gcatttgcag aatttgagcg taatttgatc ctggaacgat ccgcagcagg
      601 acgagcagct gctcgtgcaa gaggacggtt tggtggtcgt cctgaaaaat tgtctgaaca
      661 agatttggaa ttactgaaga ctttagtgga tagcggtaca cctattaaga ctattgcgga
      721 acggtggaac gtctcaagaa ccaccattta tcgttatttg gcaaaaatgg aggagaaaaa
      781 tggaaagaca aattctcatt agtttttgtc atttaatgct gaaaattttt gccatttatc
      841 tagaaaagtg acaatagtat gagaattttt tgtaagtgtc tactgataac ttattctcaa
      901 atgttgtaag gattttattc atttgttaat atta
//
LOCUS       DAFLWQ010000243          906 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.252, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000243 DAFLWQ010000000
VERSION     DAFLWQ010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..906
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.252"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..648
                     /locus_tag="L1V16_003127"
     CDS             <1..648
                     /locus_tag="L1V16_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBN1277380.1"
                     /translation="MMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLP
                     SGAENPHNFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIK
                     AKERNPEVTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIE
                     ERISDGQLDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            665..>906
                     /gene="ybeY"
                     /locus_tag="L1V16_003128"
     CDS             665..>906
                     /gene="ybeY"
                     /locus_tag="L1V16_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBN1277381.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPV"
BASE COUNT          319 a          165 c          204 g          218 t
ORIGIN      
        1 atgatggtag ctaatctaag tgctaacgct gtagcagaaa tcggcggacg ttctttgcta
       61 actcgagtag cttgctatta tcatgatatc ggcaagatca aacatgctag ctttttcgtt
      121 gagaacttgc cttcaggagc ggaaaacccg cacaatttct tattgccaga agacagtaaa
      181 catattatct ttggacatgt gacagatgga gccaaaatat tggaagatta taatatgccg
      241 caaatggtga tcgatatttg caaacagcat catggaacca cgctaatgcg ttatttctac
      301 atcaaagcga aagaacgcaa tccggaagta acagaagagc aattccgtta tcctggacca
      361 aaaccgcaaa gtcgtgaagc agggatcgtc aatattgctg acagttgtga ggctgcagta
      421 cgggcaatgg atcatccgac gagcgaaaaa atcgaaagtt ttgtccataa tcttatcgaa
      481 gagcgtattt ccgatggtca attagacgat agtggactga ccttgaaaga aatccgaaaa
      541 gtggaaaaat cattgatcag cggtttaagt agcaccttcc attctcggat caaatatcct
      601 aaaatgaaaa cagaagttga gaagataaag gaagaacaag aagaatagaa agaagcgatg
      661 tataatggat attaccttta tggatgaaac aaaccaagtc tcagaagaga aaatgaaaga
      721 aatcgatgac ttgctgcaat ttgcagcatc ttatttaaag ctgccagagg aaacagaaat
      781 gtctgttact ttcatggaca atgcggcaat ccaagtaatc aatcgtgatt accgtggaaa
      841 agatgcaccg acagacgtca tcagttttgc tctggaagaa gaaggcgaag acgaaatccc
      901 agtgat
//
LOCUS       DAFLWQ010000244          883 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.253, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000244 DAFLWQ010000000
VERSION     DAFLWQ010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..883
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.253"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..324
                     /locus_tag="L1V16_003129"
     CDS             <1..324
                     /locus_tag="L1V16_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HBN1277382.1"
                     /translation="VKTVFEEERNMRKHVAFGILALFMGVIFQLDRIEWLWLLLAVFL
                     VWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMAAGAVLVTACFAVIIGLILFVPKIY
                     HLLFN"
     gene            339..>883
                     /gene="era"
                     /locus_tag="L1V16_003130"
     CDS             339..>883
                     /gene="era"
                     /locus_tag="L1V16_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBN1277383.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQV"
BASE COUNT          271 a          151 c          196 g          265 t
ORIGIN      
        1 gtcaaaaccg tttttgagga agaacgcaat atgaggaaac atgttgcgtt cggtatcctt
       61 gctttattta tgggcgtgat tttccagctt gatcggatag agtggttatg gctgctttta
      121 gctgtttttc tcgtttggat agtagagatc atcaatactg tttttgaaaa tgtagtggac
      181 atgtttacgg attttcattt tcatccgatt gggaaaaaaa tcaaagatat ggcagctgga
      241 gcagttttag tgaccgcttg ttttgctgtc atcattgggt tgattttatt tgtccctaaa
      301 atatatcatt tgttgtttaa ttaaaaagga gaacgtatat gccagaacat aaatcagggt
      361 ttgtcgcaat cgtcggccgc ccgaatgtag gaaaatccac attattgaac cgaatcgtgg
      421 gtcaaaaaat tgccattatg agtgacaagg cacagacaac tagaaataaa atccaaggag
      481 tatatactac accagaagct cagctgattt ttatcgatac accaggaatc cataaaccaa
      541 agcatcgtct aggagatttt atggtagaag cagcttacag tgcgttgaaa gaagtggatg
      601 cagtcttatt tatgatcagt gctgatcaaa aacgcggccg gggagacgat tttattattg
      661 aacgtctaaa aaacgtgcat tctccagttt atctgattat caataaaatc gataagatcc
      721 atccagacga gttgctggga atcatcgaag attattcgac gcagatgcct tttgcacaag
      781 tgattccgat ctctgctaca gaaggaaaca atgtcgaacg cttaatggat gtattagtca
      841 gtgaaatgcc agagggccca caatattttc cagatgatca agt
//
LOCUS       DAFLWQ010000245          871 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.254, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000245 DAFLWQ010000000
VERSION     DAFLWQ010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..871
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.254"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            67..651
                     /locus_tag="L1V16_003131"
     CDS             67..651
                     /locus_tag="L1V16_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HBN1277384.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYGPDDKKSETYANENTMGSVAPGKQM
                     DVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV"
     gene            765..>871
                     /locus_tag="L1V16_003132"
     CDS             765..>871
                     /locus_tag="L1V16_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
                     /protein_id="HBN1277385.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKG"
BASE COUNT          355 a          128 c          162 g          226 t
ORIGIN      
        1 cacacggact catacctcat ttctgagatc gcaaatatat tataacaaga agtgaggaat
       61 atttaaatgg caaaaaaagt tatgggtcaa gacggaaaaa tgtataaagt tagtaaacct
      121 ttttacaaaa aagtatggtt ttgggtatta gcagtaattt taattataat tattggttct
      181 gctttaaatg gtggatcaga tagtaataaa gcaagtgata atggtggcga aaaagtaact
      241 aaatcttcaa cctctgcttc atcttctaaa gaagaaaaaa gcgatacctt ctataagatt
      301 ggtgacactg taaaagttgg tgatgctgaa tatacactaa atagtgtaga actaactgat
      361 gaaagaaatc aatttgaaga aaaccaacct gcacaagtag taaaaattac ttataccgta
      421 aaaaatgatg gcgattcaga tatccctgta ggtacagatg tggaagtata tggaccagat
      481 gacaaaaaat cagagacata tgccaacgaa aatacaatgg gatctgttgc tccaggaaaa
      541 caaatggatg taactgctca tttcacgtta aaccaaaagg gagaaataga aatccacttc
      601 tctcctttag tatcatttga aaaagcagct atttttaaag caactgtata ataaataaaa
      661 aacacgccca ccgtccaaag caagcgtgtt ctaagaaaaa caaacctata cagtaggctt
      721 ctttatagtg cctattgtat cagagaaaga gagtagattc aattatggca agattagtca
      781 aacgtggaaa tagttggcaa tacgaaattt catacaaaaa agatgacgga aaatacacga
      841 agataagaaa atcaggattt aagacaaaag g
//
LOCUS       DAFLWQ010000246          871 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.255, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000246 DAFLWQ010000000
VERSION     DAFLWQ010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..871
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.255"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            134..307
                     /locus_tag="L1V16_003133"
     CDS             134..307
                     /locus_tag="L1V16_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277386.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
BASE COUNT          290 a          143 c          106 g          332 t
ORIGIN      
        1 ttcggagaat taaaaaatac aataaataac tttagttact ttaatgcgtt cttactttat
       61 ttttatatta tcatttttct tattcacttc tttggtttat actattctta taaataaaaa
      121 cgaggtatgt cctatgatga aaagattgta ctattcattg atcataacga ttggctattt
      181 gattgtatca aatctaggaa atatggtatt tggtatcagt aaagaattca gttggactac
      241 tacattatgg gaatctctat tctttttcat cttcgtattt ttgttacaaa attatcgaaa
      301 aaaataaaca tgtgccatct atctgttggc acatgtttta ggatttatgg tactttttat
      361 tcggcaatcc attttatttt tctacttctt cttaatacct ctaacacttt tgatttataa
      421 actaatccaa tgcatctact tgcgcttatt aagctatttc agctagatag taccacccca
      481 tgcgtcaatg cttgattttc cttttgtata acattgtata agcaataaag gacaaataag
      541 tggtgattac accaaaccat tgaataagaa aaattctgat acgtaaataa acatgaactt
      601 gaaaaaatta atgaatcggt tagctactac gtagttgtct tttttctcat acagttctgt
      661 taacttacac ttctcttcgc tagataataa aaaatcctcc aactgtattg tccaatataa
      721 tcccaggcat ctaaactagc attatagaag agacacacat agaatctaaa ataactggtt
      781 ttaaatgttt cttacaatca aaaaaagctg ttaaatgcac tccacacctt catactctat
      841 cattttttat aaacgatata tttttattgt t
//
LOCUS       DAFLWQ010000247          868 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.256, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000247 DAFLWQ010000000
VERSION     DAFLWQ010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..868
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.256"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..764
                     /locus_tag="L1V16_003134"
     CDS             <1..764
                     /locus_tag="L1V16_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277387.1"
                     /translation="ETNTANFAMEVHDLTFAMGVFFLYYVFFENKNTKKHKIKIIVSL
                     ILIFMGLKRIELLALSGAILVYYVLLKWGKKIQIRALVCTICATVISLVFIYIIDTGI
                     LALLMSNLGITDDGARLSFYLYSSKFYELGLGYVGTGWTWFSKYFFNLYLSHFRLNGG
                     RIAASLHSDILTIYIEVGCIVFIIWMFWLFFVKPIRLTKKFGLKTGECVLLLTIYMFI
                     LYLTDNTLTYPDTQMIFLLVPMIVSWVDNQQRISE"
BASE COUNT          290 a           85 c          159 g          334 t
ORIGIN      
        1 gtgaaacaaa tactgcaaat tttgctatgg aggtacatga tttaactttt gcgatggggg
       61 tttttttcct ttattacgta ttttttgaaa ataaaaatac aaaaaaacat aagataaaaa
      121 ttatcgtatc tttaatttta attttcatgg gattgaagag aattgaactg ttagctttaa
      181 gtggtgcaat tctagtgtat tatgttttat taaagtgggg aaaaaagatt caaatccgtg
      241 cattagtgtg tactatttgt gcaactgtta tttcgttagt gtttatttac attatagata
      301 caggaatttt ggcattgctt atgtcaaatt tgggcattac agatgacggt gcaaggcttt
      361 cattttatct atattcatct aaattttatg aacttggttt aggatatgta ggaacaggat
      421 ggacatggtt ttcaaaatac ttttttaatc tttatttatc gcactttagg ttaaatggtg
      481 gaagaattgc agcaagccta cacagtgata tattaactat ttatatagaa gttggatgta
      541 tagtttttat tatatggatg ttttggttat tttttgtgaa accgataaga ctaactaaaa
      601 aatttggatt gaaaacaggg gagtgtgtat tattattaac tatatatatg tttatattat
      661 atttgacgga taatacgctc acttatccag acactcaaat gatttttctc ttagtaccta
      721 tgatagtttc gtgggttgat aatcaacaac gaatatcgga atagatagct aaagtatatt
      781 ttaattatga atttataatt agttgtaaaa gttaatattt aacggacagg aagtagggtg
      841 aaaaaatttg aaaaaaattt tagtgtta
//
LOCUS       DAFLWQ010000248          847 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.257, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000248 DAFLWQ010000000
VERSION     DAFLWQ010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.257"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(37..237)
                     /locus_tag="L1V16_003135"
     CDS             complement(37..237)
                     /locus_tag="L1V16_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBN1277388.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            633..782
                     /locus_tag="L1V16_003136"
     CDS             633..782
                     /locus_tag="L1V16_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277389.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
BASE COUNT          272 a          145 c          134 g          296 t
ORIGIN      
        1 ttttctttcg aaaagacggt taaaagtcaa tttttattaa gctttaacaa tgtttgttgc
       61 ttgagggcca cgttgaccat cttcaacatc gtaagacact gcttggcctt cttctaaagt
      121 tttgaagccg tcaccttgga tagctgaaaa atgtgcaaat acatcatttc catcttcacc
      181 agtgataaag ccaaaacctt tgtctgcgtt gaaccatttt actgtaccgt tattcataaa
      241 taaattcctc ctgatacgta tcaatgtacg ttttttcgtt gcaataaata tttgataggc
      301 aaaaggagtt ttatctatgt agatatatcg ctcaaattac gtttcaaaat agattactca
      361 tttaatatat catgcttttt ctaataacac aaggataatg caatgaaata taaaattcat
      421 tgtcttctat tgtcttcgaa tcgaagaaaa agttgaataa ccgcgattga ttcacttttt
      481 gttttcttgt ttatttgctt ttatctgcaa cttttgactt taaaatttct taactatgaa
      541 aacctttcaa ttggtggtat acttataaat ggaatttcgt tatcaacgcg ttcgttgcct
      601 ttcagcaagt atttaaagaa aggagaatgg ctatgacatt ctataacaaa gatatacaat
      661 atcgagtaac cttggataca gatttgaatc tatttgtcgt ttttgacaaa gaaaatacca
      721 atcatgtagc gacaggtgtt acgatcgaac aagcagtgca agaattaaaa aaatctgcat
      781 aaggagtgga aaccctcata tggacgattc tcgttcttct ctttaaacgc atctactggt
      841 agataac
//
LOCUS       DAFLWQ010000249          843 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.258, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000249 DAFLWQ010000000
VERSION     DAFLWQ010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..843
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.258"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(30..102)
                     /locus_tag="L1V16_003137"
     tRNA            complement(30..102)
                     /locus_tag="L1V16_003137"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(67..69),aa:His,seq:gtg)
     gene            complement(105..178)
                     /locus_tag="L1V16_003138"
     tRNA            complement(105..178)
                     /locus_tag="L1V16_003138"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Trp,seq:cca)
     gene            complement(185..265)
                     /locus_tag="L1V16_003139"
     tRNA            complement(185..265)
                     /locus_tag="L1V16_003139"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(229..231),aa:Tyr,seq:gta)
     gene            complement(267..342)
                     /locus_tag="L1V16_003140"
     tRNA            complement(267..342)
                     /locus_tag="L1V16_003140"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(307..309),aa:Phe,seq:gaa)
     gene            complement(378..450)
                     /locus_tag="L1V16_003141"
     tRNA            complement(378..450)
                     /locus_tag="L1V16_003141"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(415..417),aa:Asp,seq:gtc)
     gene            complement(460..532)
                     /locus_tag="L1V16_003142"
     tRNA            complement(460..532)
                     /locus_tag="L1V16_003142"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(497..499),aa:Val,seq:tac)
     gene            complement(548..619)
                     /locus_tag="L1V16_003143"
     tRNA            complement(548..619)
                     /locus_tag="L1V16_003143"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(584..586),aa:Glu,seq:ttc)
     gene            complement(634..723)
                     /locus_tag="L1V16_003144"
     tRNA            complement(634..723)
                     /locus_tag="L1V16_003144"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(687..689),aa:Ser,seq:gga)
     gene            complement(763..836)
                     /locus_tag="L1V16_003145"
     tRNA            complement(763..836)
                     /locus_tag="L1V16_003145"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(800..802),aa:Asn,seq:gtt)
BASE COUNT          236 a          232 c          192 g          183 t
ORIGIN      
        1 ccgcttggct ataccccaag aataaaaagg gcgaatgatg ggaatcgaac ccacgaatgc
       61 cggagccaca atccggtgcg ttaaccactt cgccacattc gccatggcag gggcagcagg
      121 aattgaaccc acactaacgg ttttggagac cgctgttcta cctttaaact atgcccctat
      181 aaaatggagg agagtggatt cgaaccactg aaccctaagg aacggattta cagtccgtcg
      241 cgtttagcca cttcgctact cctccatggt ggcgcgggac agaatcgaac tgccgacaca
      301 cggagcttca atccgttgct ctaccaactg agctaccgcg ccatatttta aaattattaa
      361 ttgaataaca agaacgacgg ttccgacggg aatcgaaccc gcgatctcct gcgtgacagg
      421 caggcatgtt aacccctaca ccacggaacc agttcattat ggaggttaac gggatcgaac
      481 cgctgaccct ctgcttgtaa ggcagatgct ctcccagctg agctaaacct ccaacattca
      541 attaaaatga cccgtacggg attcgaaccc gtgttaccgc cgtgaaaggg cggtgtctta
      601 accgcttgac caacgggcca ggtaaatttg ctacggagag taagggattc gaacccttga
      661 gacagtttgg caccatctac atgatttcca atcatgctcc ttcggcctct cggacaactc
      721 tccagagtga aagaagctca atactctttc tcaaaatgag aactccggca gtaggactcg
      781 aacctacgac atcatgatta acagtcatgc gctactacca actgagctat gccggaataa
      841 cat
//
LOCUS       DAFLWQ010000250          829 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.259, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000250 DAFLWQ010000000
VERSION     DAFLWQ010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.259"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..>829
                     /locus_tag="L1V16_003146"
     rRNA            <1..>829
                     /locus_tag="L1V16_003146"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          210 a          182 c          254 g          183 t
ORIGIN      
        1 agtgaagaag gttttcggat cgtaaaactc tgttgttaga gaagaacaag gatgagagta
       61 actgttcatc ccttgacggt atctaaccag aaagccacgg ctaactacgt gccagcagcc
      121 gcggtaatac gtaggtggca agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc
      181 ggtttcttaa gtctgatgtg aaagcccccg gctcaaccgg ggagggtcat tggaaactgg
      241 gagacttgag tgcagaagag gagagtggaa ttccatgtgt agcggtgaaa tgcgtagata
      301 tatggaggaa caccagtggc gaaggcggct ctctggtctg taactgacgc tgaggctcga
      361 aagcgtgggg agcaaacagg attagatacc ctggtagtcc acgccgtaaa cgatgagtgc
      421 taagtgttgg agggtttccg cccttcagtg ctgcagctaa cgcattaagc actccgcctg
      481 gggagtacga ccgcaaggtt gaaactcaaa ggaattgacg ggggcccgca caagcggtgg
      541 agcatgtggt ttaattcgaa gcaacgcgaa gaaccttacc aggtcttgac atcctttgac
      601 cactctagag atagagcttc cccttcgggg gcaaagtgac aggtggtgca tggttgtcgt
      661 cagctcgtgt cgtgagatgt tgggttaagt cccgcaacga gcgcaaccct tattgttagt
      721 tgccatcatt cagttgggca ctctagcaag actgccggtg acaaaccgga ggaaggtggg
      781 gatgacgtca aatcatcatg ccccttatga cctgggctac acacgtgct
//
LOCUS       DAFLWQ010000251          789 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.260, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000251 DAFLWQ010000000
VERSION     DAFLWQ010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..789
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.260"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            22..714
                     /locus_tag="L1V16_003147"
     CDS             22..714
                     /locus_tag="L1V16_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBN1277390.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATVATTTTTSTESKSTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADKSAQLEAF
                     MTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSESGTGQA
                     DYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELK
                     NGFNQIVYGQAN"
BASE COUNT          282 a          151 c          158 g          198 t
ORIGIN      
        1 aaaaaaagga ttttagtaac aattggtcta gcttttttgt tagctggttg taccaacggg
       61 aatgaatcga aaaaagaatc aacaaaagaa acagcgaaag caacagttgc aactactaca
      121 acaactagca cagagagcaa gtcaactgca gcaagtacag aaacagcaga tacctctact
      181 tcgtcagagt cttccaaaac gactgaaaca actcaaacat ctacttcaag ttcttctgta
      241 gaggcttcat cttcctcttc agaaagcagc gaacaagttg aacaaacact gtggaatgca
      301 gacaaatccg cacaattaga ggcatttatg accaaatggg gccaaacaat gggacaacaa
      361 tacaaaagtt atacgaatca aatgagtgtg gacttatatg gtcttaaagt ccctcaagct
      421 attttgaacg gggagtggaa gatggctatt ggtggagtgc ctgtttctgc agaatggtca
      481 gaaagtggga caggtcaagc agactatcaa atcacagccg tctattccga tgcagagaca
      541 gaaccatatc tgaaaaagca cgtctatcta ttcgggtttc agcaaaatca gccaaaagta
      601 ttggtgacac aacaaaatca ggggaatccc gataattatc tttacttcaa cgagacagcg
      661 aataatgaat tgaaaaatgg ctttaatcaa atcgtttatg gacaagcaaa ttaatgagat
      721 aaacaagggg ttgtgacatg tcttttatca caaccccttg ctcagtttat ttgttagtct
      781 tttattttt
//
LOCUS       DAFLWQ010000252          772 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.261, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000252 DAFLWQ010000000
VERSION     DAFLWQ010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.261"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..190)
                     /locus_tag="L1V16_003148"
     CDS             complement(<1..190)
                     /locus_tag="L1V16_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBN1277391.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFTASHFE"
     gene            complement(208..528)
                     /locus_tag="L1V16_003149"
     CDS             complement(208..528)
                     /locus_tag="L1V16_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1277392.1"
                     /translation="MITFERIKELAKKQGKSLNKVEEDLGYGKNVLYRLKNSNPSTER
                     LQEIADYFDVSVDYLLGREEKETPKHVDLSENDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
BASE COUNT          247 a          143 c          101 g          281 t
ORIGIN      
        1 attcaaaatg agaagcggtg aaatgcgcaa gttcatgaga taaatgaaag gcttctgcag
       61 tttcgccata tagattttca ttcaaaaaaa tgattctagg cttcggataa tagaagccag
      121 gctctttcat ttccatgtaa actactttca aattgtattc gctcaacatt tctttcaatt
      181 tcaaatacat acaacccatc actccaacta ttcattttcc tctaaagctt tagcaattgc
      241 aatcgcttta cgcattgtct ccttagatat ttcttttcca tcaaaagaaa aaacagtatc
      301 gttttctgat aaatccacat gtttaggggt ttctttttct tcgcgcccca gaagatagtc
      361 tacagagaca tcgaaatagt cagcaatttc ttgcaaacgt tctgtagagg ggtttgagtt
      421 cttaagtcta tataagacgt ttttaccata gcctaggtct tcttcaactt tatttaatga
      481 ttttccctgt tttttcgcta actcttttat tctctcaaac gttatcatat caatattcct
      541 ttcgttcaag aaaaaatatt taactttatt tgttaaaatt cgttgactat tttaacaaaa
      601 ggtgttaata tcattcttgt aaacaagttt aacaactaaa aagacaacaa aaaacactat
      661 cgattaataa atgccaaccg ccaagaaagc ttttaaaatc aatgtttata tgtcttattt
      721 aactatgttc tgattttaac actgtatgtt aatttagtca acgcagtttt tt
//
LOCUS       DAFLWQ010000253          766 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.262, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000253 DAFLWQ010000000
VERSION     DAFLWQ010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..766
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.262"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            47..718
                     /locus_tag="L1V16_003150"
     CDS             47..718
                     /locus_tag="L1V16_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1277393.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
BASE COUNT          309 a          115 c          119 g          223 t
ORIGIN      
        1 acagaattaa aatatcagtt aaaataaaag ttaaggagca ttgtgtatga caattaaaac
       61 tagtctccaa aatcaagctt accaatctat tcgccgacaa attatctatg ctgacttaga
      121 acctggaaaa aaagtatcag aaaaaaaatt agaagaaaca ctttctattg gtcgtacacc
      181 aatacgtgaa gcactgattc aactccgaca acaaggtctt gttgatacaa ttcctcaaag
      241 cggaaattat atctcattaa ttgatttaga ttcggccaaa aatgctcgat ttgtcagaga
      301 acatttggaa cgacaaatta tgttagagtg ttgtgccaaa atgaataacc aaaaaaaacg
      361 gattttagaa actataattt cagaacaaga aaaagctgtt agtcaaaaaa atgctcgtag
      421 tttttttcat aatgataatt tattccataa agcttgtttt gaaattgcag agcgagaaga
      481 agtatggcaa tggttagaaa ataacaatac acacttagaa cgatttcgat ggctacgagt
      541 aaaaacggaa ggattaaagt gggaaaaaat tatggaacaa cattatcaac tatttgaggc
      601 attaacaaaa caagatccag aagaagctaa ctttctaaca tcgttgcatc ttcatttaat
      661 gcttaatgag caaaatattg ttttagctac tcatccaaaa tatttcaaaa atatataact
      721 tttaactctt tttaaattaa atggttgttc tgatcagaaa aatatc
//
LOCUS       DAFLWQ010000254          731 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.263, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000254 DAFLWQ010000000
VERSION     DAFLWQ010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.263"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            22..731
                     /locus_tag="L1V16_003151"
                     /pseudo
     CDS             22..731
                     /locus_tag="L1V16_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890625.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT          254 a          133 c          133 g          211 t
ORIGIN      
        1 cttaccatag acgaactgac aatgatagaa tcatattatc ttcaacataa taagccggtt
       61 gaaatcgcta accgaatggg acgtgctata caaactattt ataatgtagt caataagttc
      121 aagcaaggca agactgctct tgattattgg caccagtata aagaaaataa gaaaaaatgt
      181 ggtagaaaag tcattcaatt acctgctcat gaagtagatt acattaaaga gaaagtcact
      241 cttggttgga cgcctgacgt cattatcggg cgaaaagaaa ggcctgtttc atgcggtatg
      301 agaacacttt atcgtttatt ttctaaagga atatttgata ttgacacact accgatgaaa
      361 ggtaaaagaa aacccaatgg ccatcaggaa aaacggggaa aacaacagta tcagcgctca
      421 atccatgatc gacctgataa ttatcctcat ttcaattctg agtttggtca ccttgaaggt
      481 gatacgatcg ttggcattca tcataaaagt gccgtcatta ctttagttga aagattatct
      541 aaagtcatta tcacgattaa acccaacggc cgtaaggcat tagatattga aactgccctt
      601 aatcaatggt tttctcgctt ccctaaaaac ttctttaaat ctattacgct attacgtttg
      661 actgtggaaa agaattttct aactggaaag ccattagtaa ccaacatgat attgatatat
      721 attttgcgga c
//
LOCUS       DAFLWQ010000255          717 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.264, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000255 DAFLWQ010000000
VERSION     DAFLWQ010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..717
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.264"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..263)
                     /gene="recO"
                     /locus_tag="L1V16_003152"
     CDS             complement(<1..263)
                     /gene="recO"
                     /locus_tag="L1V16_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBN1277394.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQED"
     gene            complement(406..>717)
                     /locus_tag="L1V16_003153"
     CDS             complement(406..>717)
                     /locus_tag="L1V16_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBN1277395.1"
                     /translation="EKVLFLTRDEVPHSVAVVVDSMKRNENDKIHIQATIIVERDSQK
                     GIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWVKVQKDWRDKKVYLQDFGYRKDE
                     Y"
BASE COUNT          185 a          157 c          123 g          252 t
ORIGIN      
        1 atatcttctt ggatgttccg aaacgcatgg acgtctttga cactgcttaa aaacgacaaa
       61 ccttcacttc gaaaattacc gatatagact gcttcggtaa aggggagcaa agccggagct
      121 aatggctgat tttgccgatg gattcctttg atataaaaca tcattttgcc agaagattcc
      181 gtaaagattt tgactaattt atctttttct ttgtaattac ggctagataa aatcaagcct
      241 ttcgattctg caagctggct catattctcc ctcctaaaaa ataaatctgg aaaagcagat
      301 tctgccgatc cagattattt atgttacgat cttccgctgt ttttctcaac gtacggattt
      361 ttatccagtt tatttctata cctaacctat aagaagtcca gaatatcagt actcgtcttt
      421 tcggtagccg aagtcttgca gatagacttt tttgtctcgc cagtcttttt ggactttgac
      481 ccaaagttct agaaatactt tgtctcctaa aagattttcg atatcctttc ttgctttcgt
      541 tcctacttgc ttcagcattt ttccgccttt gccgataatg attccttttt ggctatctct
      601 ttcgacgatg atcgtggcct ggatatggat tttatcattc tcgtttcgct tcatcgaatc
      661 aacaacgact gcgacagaat gaggcacttc gtctcgtgtt aaaaacaaga ctttctc
//
LOCUS       DAFLWQ010000256          693 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.265, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000256 DAFLWQ010000000
VERSION     DAFLWQ010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..693
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.265"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
BASE COUNT          243 a          119 c           82 g          249 t
ORIGIN      
        1 attgacgctc cctccaaatt acttcatcaa aacattgata taatttttat tatatcagta
       61 tttattcttg atacataaat gagaaaataa atactttaaa tctattgact acaagtagtc
      121 attaagtctt cataagatgt acaatatgac attaaaaaaa taaaagctta cgaccatccg
      181 ttaaatctga cactaaataa tggactgctt tcttttgtat tagcaggtta cgttgactat
      241 gaatattcac cagattattt ggagaaacct cttcaacacg agaacaatga tattaatttt
      301 agatttgtct acgagtcaaa aagtaaaaca tggttagttg atcaattaag cacgataaac
      361 acaagcttcc atgaattacc taaacctgaa aatgaagttg agatggtcat taaaatcttc
      421 taaaaaagaa gcgttgaagg ggaaatattc ctttcaacgc tcttttttat atgcttagaa
      481 acataaataa attgtatact ttctttttag cccctattac ttttcacgaa aaatatcttt
      541 ttttcgacgc tagcgtttct ctacttctaa tactgtacac agtttttgta ttattgaaaa
      601 attactcatt atttagcatt aatccacatc gttttatcaa tcgaccttca tactaaacta
      661 ctttaaagtc atcttccttc tcgtttttca tta
//
LOCUS       DAFLWQ010000257          666 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.266, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000257 DAFLWQ010000000
VERSION     DAFLWQ010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.266"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            241..639
                     /gene="spxA"
                     /locus_tag="L1V16_003154"
     CDS             241..639
                     /gene="spxA"
                     /locus_tag="L1V16_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBN1277396.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT          237 a           97 c          125 g          207 t
ORIGIN      
        1 tgtttcatat gtttagaaaa tttgaattag atttgaaaac tctaattttt aaatgataaa
       61 aaaagcgaga atgctggttt tactgtatat taaccttaga taactttcat ttttttaaaa
      121 aaattatgaa aaaaaggtag ctatttaaaa gttgattatg tataatagaa acagatggga
      181 gattattatg atcttctgtt acaaaaaagt gattcttatc acgaaaagga gtggtgcacg
      241 ttgttaacat tatatacttc cccaagttgt acttcctgca gaaaggctcg tgcgtggttg
      301 caagaacatc agattccatt tgttgaacgt aatatttttt cagaaccatt gaacagttct
      361 gaattaaaag cgattttaca aatgacagaa gacggaacag aagaaatcat ctcgacacgt
      421 tccaaagtat tccaaaaact gaacatggat ttagatgatc tgccgttaca agaattattg
      481 gaacttgtgc aaaacaatcc tggattgctt cgccgtccaa tcatgattga tgataaacgt
      541 ctgcaagttg gttttaatga agatgaaatt cgtcggttcc taccgcgcga tgtacgacaa
      601 ttagaattac gtcaagcaca attgatggct ggattataga aggataatac gaaacttgga
      661 aaagac
//
LOCUS       DAFLWQ010000258          639 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.267, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000258 DAFLWQ010000000
VERSION     DAFLWQ010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.267"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..556
                     /locus_tag="L1V16_003155"
     CDS             <1..556
                     /locus_tag="L1V16_003155"
                     /inference="COORDINATES: protein motif:HMM:NF012744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1277397.1"
                     /translation="KLMNLRTRKKRLKFLFVGRVTLEKGIGVLDSFFEKFGIEDAWTF
                     AGDYSDSKKFYEKYEDKVQFVGHVSKIKMFELYRDNDVLVFPSLADGFGLAVIEALSN
                     GMYVICSDSTGAKDIIMEGKNGDVFLTGDENDLNNKIQYYKKNINKIDRLKIKETVND
                     LTWERYNKNIIKSLEYFTVGMNNE"
BASE COUNT          257 a           49 c          114 g          219 t
ORIGIN      
        1 taaattaatg aatctaagaa caagaaaaaa aagattaaaa tttttatttg tgggaagagt
       61 aaccttagaa aaaggaattg gggttttaga tagttttttt gaaaaatttg gaattgagga
      121 tgcatggaca tttgctggcg attattcaga ttctaaaaaa ttttatgaaa aatatgaaga
      181 taaggtacaa tttgtgggac atgtatcaaa aataaaaatg tttgaactgt acagggataa
      241 tgatgtttta gtatttcctt ctttagcgga tggttttggt ttagctgtta ttgaagcatt
      301 aagcaatgga atgtatgtta tatgttcaga ttctacaggt gctaaagata ttattatgga
      361 aggcaaaaat ggagatgtgt ttcttacagg agatgaaaat gatttaaata ataaaataca
      421 atattataag aaaaatataa ataagattga tcgtttaaaa attaaagaaa ctgtaaatga
      481 tttaacatgg gaacgttata acaaaaacat tataaaatca ttagaatatt ttaccgtagg
      541 tatgaacaat gaataaatta ttaatgatgt taaacttttt ttatctctac gtatacatga
      601 ttgacgcata cggtataata aataatgatt tatatctaa
//
LOCUS       DAFLWQ010000259          639 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.268, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000259 DAFLWQ010000000
VERSION     DAFLWQ010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.268"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..161)
                     /locus_tag="L1V16_003156"
     CDS             complement(<1..161)
                     /locus_tag="L1V16_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1277398.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALE"
BASE COUNT          202 a           94 c          105 g          238 t
ORIGIN      
        1 tattctaagg ctgattttcc ttgcttgaag aacagatata ctttatggat cgtttgtctt
       61 gaacgattca agcaatgggc agttttagca acagattgat tcattttgaa ataagactct
      121 attattacaa gttcatccgt tgtaagatgg gtataggtca tttgtactca ctccttataa
      181 ttctttggtc ggaactattt tgagtgtagc acaaatgact tttttagttg tctagcttaa
      241 ttttacaatc ggcgacttat tgcttttgca aaatttattt acctgttttc tggatcaacg
      301 atagtgtaca ttatgctatc cttgtttgga ttttaggacg tttaaagagg cactttttta
      361 cataacttaa tccatagacc ttttaagcat gctgtgagat aataataaag aagagtttaa
      421 agcgcacccc aaaccacttc cccataagtg tattacgctt taaactcttt tatatttgaa
      481 ttcactaaga agcataccat atatttgaat ttactaagaa gcataccata tttttgaaaa
      541 aaagtgagaa aaaaggctta taattaggat ttagagtaat taattagatg tttattttat
      601 aggactgata ctatagatta caaatagtat cgtatttcg
//
LOCUS       DAFLWQ010000260          633 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.269, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000260 DAFLWQ010000000
VERSION     DAFLWQ010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.269"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            145..576
                     /locus_tag="L1V16_003157"
     CDS             145..576
                     /locus_tag="L1V16_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277399.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
BASE COUNT          247 a           93 c          128 g          165 t
ORIGIN      
        1 tggttgggtc aatagaccgt tctactttga acagtgctca actatctatt ggcgcagacg
       61 gagccattaa atggagaaga aattcaagtt atggatcagc ttattcattt gttatcactt
      121 attcaattta agggaggaaa tctaatgaaa gtagtttaca aatcaatcaa gccttacgga
      181 ttcgagcaaa tcattttgaa caatcaagaa aatatccctg aaaactgtac agagattaaa
      241 ccaccagttc ctaactggag accaagattt gattttgata aaaaacagtg ggttgagtta
      301 gctactgaag aagagaaaaa agggaatgct gttgatagcg tagatgaatt ggctaatatt
      361 aaggcattat acgaaacgct gaaggcagaa aatgatgaat tgaaacagct aaattctaaa
      421 gcaatgctaa acaatgtagc aatcaagcaa gaaaatgtct tattgaaaga aaagtcagaa
      481 agtttagcgc agttgaattc aaaaacgatg cttgcttctg tacaaaatac caaggaaatc
      541 gaagaaatca aaaaacaatt acaaggtggg aagtaacatg tattcatatg aagatatcaa
      601 actaatgtat gactggggct gtttcactaa cga
//
LOCUS       DAFLWQ010000261          628 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.270, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000261 DAFLWQ010000000
VERSION     DAFLWQ010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..628
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.270"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(153..575)
                     /locus_tag="L1V16_003158"
     CDS             complement(153..575)
                     /locus_tag="L1V16_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277400.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
BASE COUNT          200 a          104 c           92 g          232 t
ORIGIN      
        1 agattagaaa ttgatttttg aattttttgt gtctcctgta aagttcgctg aacttgtaaa
       61 gctgattctt ctttcggtaa attaatttta cttagaatat cgctatcttg ataaaaattt
      121 ggtgtgttca caaattctgg cataaaaaat ccctactttc tagttaaggt tcctgaataa
      181 gtcgcaatcc aattgtttcc agctgattta taactttgta aatacaattt tccatagtac
      241 caataaccat ttcttttttc tttccaattc cgtgattgag gaggtctaga aggccaacca
      301 actttatcaa aaatcatcgt tcctgtcact cgtatcgttt tagaagctgc tcgagcaagt
      361 aatggagaaa ctattaaata attttcagta acagttaagt cgttagttgg gttaccaatg
      421 gctattccgt tcctatctaa aggagttaat tcttggttat tatctactac agtagttggt
      481 tcatttgtac tatcagcaaa tgtaggaatt gtagttccag ttacactaat tccaatagtt
      541 aaaataccta aagataaaat aaacttattt ttcattgtct atcacctcga aatcaaaaat
      601 aagaaaacgt tttcttaata aatcttaa
//
LOCUS       DAFLWQ010000262          625 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.271, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000262 DAFLWQ010000000
VERSION     DAFLWQ010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.271"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            1..625
                     /locus_tag="L1V16_003159"
                     /pseudo
     CDS             1..625
                     /locus_tag="L1V16_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
BASE COUNT          214 a          110 c          118 g          183 t
ORIGIN      
        1 atgactaaag tgctgactga agaagtaaat gcatttaaag ttagaactct aaatgataag
       61 tatgtcgcta ttttcatgga tgctacttat attcctttaa aacggcaaac cgtctccaaa
      121 gaagcaatct atattgccat tggtatacga gaagacggca ctaaagaagt actaagttat
      181 gcgattgctc cgactgaatc gacctacgtt tggaatgagt tgttacagga catttactcc
      241 agaggggttc atgatgtctt actgtttatt accgatggct taaaaggcat gaaagatacg
      301 attcaccaga tttatcctaa agctaaatac caacattgct gtgttcacgt ttcccgtaat
      361 attgctcata aagtacgtgt caaagatcga aaagaaatct gtgatgattt taaggctgtt
      421 tatcaagcta gctcaaagga agaggcaaat acctttttag ggagtatgat tgagaagtag
      481 caaaaaactt atcctaaagt gacgcagtca ctgataaaaa atcaagattt attgactttt
      541 tatgagtttc cgcctggtat ccgccgaagc atttactcaa ctaatttaat cgaatctttc
      601 aagaaacaaa tcaagaaata cagcc
//
LOCUS       DAFLWQ010000263          593 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.273, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000263 DAFLWQ010000000
VERSION     DAFLWQ010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.273"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(318..581)
                     /locus_tag="L1V16_003160"
     CDS             complement(318..581)
                     /locus_tag="L1V16_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HBN1277401.1"
                     /translation="MKKNLLLVLPILGFAGFFVGVPMLSANIGISSYAAKKVIDIINT
                     GSTVATIISIVAAVVGGGLITAGIVATAKSLIKKYGAKYAAAW"
BASE COUNT          224 a          104 c           79 g          186 t
ORIGIN      
        1 gccttccttt tttgtatgga ttttttcatt tacacaaaat attttatact ctcctgaatt
       61 ttttcatgtt gaaaacatca ctaatcaaag gcaaattata atttagaaat agaatgaaaa
      121 cactaaatga aaatagaaca ttagaaaaaa tagaatcaaa aaaacccaag actagtgccg
      181 aaataaggga aacaatcgaa gctacaaaaa ataatgattt cgttgaacag gaccaattta
      241 tttgtttccg atatttctca aaaagaactt tctttgggaa agttaaaggc gactgtaaag
      301 tcgcctttag tcctttttta ccaagctgct gcatatttag ctccatattt tttaattaat
      361 gatttggctg tagcaacaat accagctgta attaatccgc ctccaacaac tgcagcaaca
      421 atagaaatga ttgtagcaac cgtgctacca gtattaatta tgtcaataac ttttttagct
      481 gcataagaag aaattccaat gttagcactt agcattggta caccaacaaa gaatcccgca
      541 aaacctaaaa ttggtaaaac taataataaa ttctttttca taataattcc tct
//
LOCUS       DAFLWQ010000264          587 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.274, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000264 DAFLWQ010000000
VERSION     DAFLWQ010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.274"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..343)
                     /locus_tag="L1V16_003161"
     CDS             complement(<1..343)
                     /locus_tag="L1V16_003161"
                     /inference="COORDINATES: protein motif:HMM:NF014051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBN1277402.1"
                     /translation="MKDRVKNVIYNAVYQVFIIVIPILTMPYVSRKLGAENLGINTYT
                     QSLVLLLGLFINSSILQIGAREIARQDRISRTKTFITLWLLQVLCGLVIIIVYILIIM
                     GSKYYYYYLLQL"
BASE COUNT          205 a           84 c           64 g          234 t
ORIGIN      
        1 gtaattgtag taaataataa taatagtatt tgctacccat aatgattaat atatacacta
       61 tgataataac caacccacat agtacttgta ataaccaaag tgtaataaat gtttttgttc
      121 tactaattct atcctgtcta gcgatttctc ttgcgccaat ttgtagaatg ctagaattga
      181 taaataatcc taaaagcaat actagggatt gagtatatgt atttatacct aagttttctg
      241 cccctaactt tcttgataca tatggcatag taagtatagg aataactatt ataaatactt
      301 gatatactgc attatagatt acatttttta ctctatcttt cattgaaagt aacctcgtac
      361 tttactaatt aaaaaaaaca actgataaat tgtttggcta tcacaataac taaaacaaaa
      421 tttgattaaa ttgcttttca tgtttttcat gtttgttttt tctaatatcg ttagaaattg
      481 actatctgac cttaaattat ttatcaattc tataacatca tctttttctt cattgttaac
      541 tattttttgt aaagacgtct gtatgatttt aaatttatta aaaacat
//
LOCUS       DAFLWQ010000265          544 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.275, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000265 DAFLWQ010000000
VERSION     DAFLWQ010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..544
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.275"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..93
                     /locus_tag="L1V16_003162"
     CDS             <1..93
                     /locus_tag="L1V16_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBN1277403.1"
                     /translation="KFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
BASE COUNT          207 a           89 c          110 g          138 t
ORIGIN      
        1 aagttcattg atcaaatgaa gtcttgggca cacgtattaa agacgccaga gaaaaatatg
       61 cctgaaaaag agatacctga aaaagaagaa taaatgaaag atacaacaaa aaaatcaaaa
      121 ctatttgaca aatacaggga cttccgtcta ttattaaccg tagattaaat agatcgttca
      181 ctgagaggat ctattataca aacaagaaaa ctgcaaaatg aatacgtaca ttgaccaaga
      241 tcagtaaaaa acacgtggtt tagcgagttc gggagagtgg aagccggacc caaacgattt
      301 ttgaagaggc acttgcgagt acgataaatg aagctgccga atctttattc ggaagtaggg
      361 tggaaccgcg aaattattcg tccctatgtc tgtaatcaga catagggact ttttgtcgtt
      421 ttctttcctg tattcttatt gacagcaacg cttaaaaatt gaaaggggca aaacagatga
      481 gtaaaaaatt gaccgtccaa gatatgattt taacattaca aaaattttgg tcatcaaacg
      541 gctg
//
LOCUS       DAFLWQ010000266          521 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.276, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000266 DAFLWQ010000000
VERSION     DAFLWQ010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..521
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.276"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            25..>521
                     /locus_tag="L1V16_003163"
     CDS             25..>521
                     /locus_tag="L1V16_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HBN1277404.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT          190 a           95 c           86 g          150 t
ORIGIN      
        1 attcacagaa aagaggactt ccctatgaat gattttacta cagaaattgt gcaaactcta
       61 gtcactaaag gcgatttaaa tgaattattc cgttcgcact tagaaaaagc gataaacaca
      121 ctcctacgga ctgaattaac ggctttttta gattacgaaa aatatgatcg cactggtttt
      181 aattcaggta attcgagaaa cggttcttac tttcgatcaa tcaaaaccga atatggtgaa
      241 ttaacattgg aaatacctag agatcgtaat ggtgagttta aacaacaaac tttaccagcc
      301 tacaaaagaa caaacgatac attggaaacc actattatcc atttattcga aaaaggtgtt
      361 acgatgtctg aaattgctga tttgatcgaa aaaatgtacg gtcatcacta tactccacaa
      421 accatgtcca acatgactaa agttctgact gaagaagtaa atgcctttaa atccagagcc
      481 ttaaatgata agtatgtcgc tatttttatg gacgctactt a
//
LOCUS       DAFLWQ010000267          508 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.277, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000267 DAFLWQ010000000
VERSION     DAFLWQ010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.277"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
BASE COUNT          228 a           70 c           81 g          129 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacatgataa gataactgag tcgttaaaaa
      301 agaaccactt gcgaagcttg attctatcga aaaaaacttc aaaaaagttc ttgacaaata
      361 acaaacgata agttatgata aatgagttgc cgaaagattt cgaaaaacga aatcgaaaaa
      421 aacttttaaa aaagagttga caatcgcttg tctctctgat atgatataaa agttgctacg
      481 gcagccaaaa atgaatcggg aaacactc
//
LOCUS       DAFLWQ010000268          477 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.280, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000268 DAFLWQ010000000
VERSION     DAFLWQ010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.280"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(385..>477)
                     /locus_tag="L1V16_003164"
     CDS             complement(385..>477)
                     /locus_tag="L1V16_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBN1277405.1"
                     /translation="RGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
BASE COUNT          152 a           90 c           72 g          163 t
ORIGIN      
        1 ttaattaagg cgactcagcc cacaaaaaaa gccccagaga atccgacctc tctggggatt
       61 tcgtgtgttt cgtgttcact tatttgcaat caaattataa cagaaataaa tatttatttc
      121 aaaaatatcc tacaaaagtc taaaatccgt aattatttct tatatgcaac atttacaaat
      181 aaagtcgctc tgagagctcg tatttttcga tttaagacgt tttatttagt ttttggtgta
      241 tttcattggt ccaagctaaa aaactcttag aagcgatttt agagccattt aaacccactt
      301 aattatattc tccatgaaat tcgctccatg ggttctgttg caaagtttta aataaagaat
      361 aaaatccctt acggtatcta tgatttaagc tgggattccc aataatacct tgatttcagt
      421 acagaccgaa aacccgaaga gagtgccttc ttttcgggtt ttcttatata atcctcg
//
LOCUS       DAFLWQ010000269          468 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.281, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000269 DAFLWQ010000000
VERSION     DAFLWQ010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.281"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..>468
                     /locus_tag="L1V16_003165"
     CDS             <1..>468
                     /locus_tag="L1V16_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBN1277406.1"
                     /translation="CVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLA
                     YTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYF
                     YGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHK"
BASE COUNT          155 a           86 c           83 g          144 t
ORIGIN      
        1 cttgtgttat atggggcata attaatggct atactagcca aagagccacg tatagagcgg
       61 tttgttccgt cttatttcct aatggtgact ttcctagtag gagtcgattc actcgcttaa
      121 gttcaaactt agcttacact atcaagatta ttcgatactt tttcatcaag aagctcacca
      181 aaggtgaact agtcggaatt atagatagtt ttcctagtcc attatgtaaa ccagttagaa
      241 atagacaagc aaaactattg aatcaaatag ccaaagttgg ctataactca acaaaaaaat
      301 cttattttta tggtcttaaa attcatatga tcgttactaa gactggcttt ccgattactt
      361 actcaatcac gaatccaggt gtccatgacg tgaaagtgtt agagacttta tcggaagaag
      421 cgaatcttcc caatatccta ggggacaaag gatatattag ccataaaa
//
LOCUS       DAFLWQ010000270          465 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.282, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000270 DAFLWQ010000000
VERSION     DAFLWQ010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.282"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
BASE COUNT          150 a           89 c           53 g          173 t
ORIGIN      
        1 agcacaaaaa ataaaaaaat tattacgtta ttaaaaaaac agatgaaaga tcaggtttta
       61 ttagatctca ttctttcatc acttgaaggg atttaatgaa ctactttttc ctctttgtcg
      121 tttttatata ttcgtattcc ttcaaacagt aggatagcct ctttcaatgc ttgatatttg
      181 aactgtccgt tacttaaaaa tttagatgtg ccgccctctt cctagaacat attctttttt
      241 actttttcat taattgacag accaatcgaa cgaaactgta aatttcgata ggataatgat
      301 tggtcaaact cattcatttt caagacatct cgattcatat tcaagatagg aatcttttta
      361 tcaacatcac tttattcgta ttttcctcta ccataaaagc ttcacgctcc acaaaattgt
      421 tttatacact actattcagc ccattcaacg accaatgaat ttttt
//
LOCUS       DAFLWQ010000271          457 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.283, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000271 DAFLWQ010000000
VERSION     DAFLWQ010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.283"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
BASE COUNT          189 a           53 c           67 g          148 t
ORIGIN      
        1 agcataataa atgattttta catcgttatt tattgatatt aatctcatcc aaaaaatgaa
       61 agcgcatact ttatgggtga ttaaatgtga ttttaataca tataccaatt aaaagaaaac
      121 ttttttagat ttttacttac aaatttataa aaaaacaaga taattgatac tttgattttg
      181 cgaacatttt atctttccgc ctaattcagc tgcaatatca tgattatatc agtaacaaat
      241 cgctttttta gctaatttaa gcatcaaata attattctta atcagtgaaa aaaataacga
      301 ataaatggat tttgggaata ggtaaaaact tgatcggttt ctggataaaa ataacatgaa
      361 aaaggaaata taaaataaca tggagcgtgg gaggaataaa gaaattttac actcgaggtg
      421 cgtaggaatg taaagaaact taacacgaaa caaaagt
//
LOCUS       DAFLWQ010000272          436 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.284, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000272 DAFLWQ010000000
VERSION     DAFLWQ010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.284"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..>436
                     /locus_tag="L1V16_003166"
     CDS             <1..>436
                     /locus_tag="L1V16_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277407.1"
                     /translation="YAESAITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSL
                     SNKLSSVKLSADDYDIKESELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTK
                     NVSNWQQAVDDVIIKEKVTSADVARVRENMSFFKDSPWKTVVM"
BASE COUNT          171 a           78 c           80 g          107 t
ORIGIN      
        1 tatgcagaat ctgccatcac caatcaaaaa gacaccttga cttctttatc aaaagaagta
       61 gacaagctgt atagtacaaa agaaaaaatt tttctaaacc ctgaaataac agaagaaaca
      121 atcacaagtt tgtcaaataa gctatcctct gtcaaacttt cagcagatga ttacgacatc
      181 aaagaatcag aattgcctaa agaagctgtt gcaatccaag atgagaagaa agcaatcgtg
      241 acacagttag atagtgcaga atcaaaactg aagatccaga cagctgtcaa cgatttattt
      301 actaaaaatg tatcaaactg gcagcaagct gtagacgatg tcatcatcaa agaaaaggtg
      361 acaagtgcag atgtcgctcg tgtacgtgaa aatatgagct tttttaaaga tagtccttgg
      421 aaaacggttg ttatgc
//
LOCUS       DAFLWQ010000273          404 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.287, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000273 DAFLWQ010000000
VERSION     DAFLWQ010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.287"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            1..268
                     /locus_tag="L1V16_003167"
                     /pseudo
     CDS             1..268
                     /locus_tag="L1V16_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751573.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
BASE COUNT          148 a           57 c           73 g          126 t
ORIGIN      
        1 atctatattt tgatatacaa attacagctt cagatactaa gttgcataaa ccttttccgg
       61 accccataca aaaggcaatt gatgaattgg gcataaaaaa taagaaacga tttatattgg
      121 tgattcatta tatgacatgc aaagtgcgaa agcttgtggg atagcatttg gtttagctaa
      181 atggggagcc aaaaatatag aaaattttca aagtgtagat ataattattg attctcctca
      241 agaaatactt gatttgttag aaaaatagac aaagagcgtg agataaggat agggtctcac
      301 gctctttgtt tttcgccatt taaagattga aatttttgcc atcgccgatt gtaaaattaa
      361 gctagacaac taaaaaagtc atttgtgcta cactcaaaat agtt
//
LOCUS       DAFLWQ010000274          400 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.288, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000274 DAFLWQ010000000
VERSION     DAFLWQ010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.288"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
BASE COUNT          136 a           59 c           48 g          157 t
ORIGIN      
        1 tttaaaaaat gataaacctc tctcgaacgg ttttttatca aaaatcgtca tttttccatc
       61 aaaatctgct tatgcaaaat tataaaaaaa ttttgcagtt tttcttactt tttttgtcgt
      121 ttaattgaat gataaaaacc agtttcttta ttcagttaat caaatatgaa cgaattagat
      181 atgaatcatt gtatttgccg ttgcggaagg attttttaat taaccacaga taaacattga
      241 taacgattcg cttattgtaa tcaacagatt aaatttcata tgttcatatg tacggataca
      301 ttttcggacc gattaatttt aaccattcta tttatttgct tacctattag atatcaataa
      361 aaaactgctt aacagctatt tcagctgtta agcagtttta
//
LOCUS       DAFLWQ010000275          397 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.289, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000275 DAFLWQ010000000
VERSION     DAFLWQ010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.289"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
BASE COUNT          110 a           98 c           76 g          113 t
ORIGIN      
        1 taaataactc ataaaaaata ttttgacttt caaaatcact tttgctacca gaagttgagg
       61 cgaagtgttt taagcatagt tgtaccctag tttgaccgtt aaaaataaat aacgatcgct
      121 agagtgcaac tatgtttgtt tgccctaccg tcagcgtcgg cttggcctct cacatccatt
      181 accgtcggga ttatctccgt tacataccct tacaaaatac gccctgtaag cattgcatga
      241 aaccaccgtg catttgcacc gtatttccgc cctagccgtt caaatcggtc gctaccacca
      301 ttcagaaaca cgtgcggtaa tggaaggttt ggaggaagct atccagacca ctaacgattg
      361 tccctatcgt cgtacgtttc actcagatca aggttgg
//
LOCUS       DAFLWQ010000276          394 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.290, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000276 DAFLWQ010000000
VERSION     DAFLWQ010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..394
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.290"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..285
                     /locus_tag="L1V16_003168"
     CDS             <1..285
                     /locus_tag="L1V16_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1277408.1"
                     /translation="EVAEDDPYWEIEASYIAQCAYNTTLMFSPDVIIFGGGVMKQRHM
                     LQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGTLGCLALAREAVLHS"
BASE COUNT          117 a           73 c           92 g          112 t
ORIGIN      
        1 gaggttgcag aagatgatcc ttattgggaa atcgaagcct cctatattgc tcaatgtgcc
       61 tacaatacaa ccttgatgtt ttctccagat gtgatcattt ttggcggtgg tgtgatgaaa
      121 caacgccata tgctgcaaaa cgtccacgac gcatttgcaa aattggtcaa tgggtatgtc
      181 gaaacacctg agttaagcaa atatatcgtg accccagcat tagaagacaa cgctggaacg
      241 ctcggttgtt tggcattggc tcgagaagcg gtcttacatt cataaacgaa aaaaggctct
      301 tcgacattta gtgttggtag agaaagatac aactgaaaat ttagtcataa ccagttaggc
      361 agagtgctta actggttttt gttttacttg gaag
//
LOCUS       DAFLWQ010000277          382 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.291, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000277 DAFLWQ010000000
VERSION     DAFLWQ010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.291"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..>382
                     /locus_tag="L1V16_003169"
     CDS             <1..>382
                     /locus_tag="L1V16_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBN1277409.1"
                     /translation="KVFAAAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVD
                     PELFENEAEKELHKAVEAMKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAV
                     RKNRLTQLSQIAAMALSLASLDQII"
BASE COUNT          139 a           77 c           83 g           83 t
ORIGIN      
        1 aaagtatttg cagcagcaca attgttcaag cagcatcttg cagatgaaga cttcaaacca
       61 tcgatggaag ctttgacacg tgtcgtgaac ttagcgaaaa aagcggagct tgaaaaacaa
      121 tcagaagtag accctgaact gttcgaaaac gaagcggaga aagaactgca caaagcagta
      181 gaggcaatga aaacaagctt tgctgaccaa acgatcaacg aaaattatga tcagcttgta
      241 agccttcgcc cactgatcga aaattatttt gatcagacga tggtcatggc agaagaacca
      301 gcagtacgta agaaccgatt aacgcaatta agtcaaattg ctgccatggc tttgtcgcta
      361 gcaagtttag atcaaatcat ca
//
LOCUS       DAFLWQ010000278          380 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.292, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000278 DAFLWQ010000000
VERSION     DAFLWQ010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.292"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..130)
                     /locus_tag="L1V16_003170"
     rRNA            complement(<1..130)
                     /locus_tag="L1V16_003170"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          103 a           95 c           64 g          118 t
ORIGIN      
        1 tgggttcccc cattcggaaa tctctggatc atagcttacg tacagctccc caaagcatat
       61 cggtgttagt cccgtccttc atcggctcct agtgccaagg catccaccgt gcgcccttat
      121 tcacttaacc ttatcaacct tacggttggg ttttgatcct tcttctagcg atagaagtta
      181 gatcaagaaa ataagcaatt gaacttatta aaaaactcta tccagctcac aaatcagcct
      241 gtacggcaaa aagatcgatc gtctcataaa atcaaagatt ttatggccgt ccgcctattt
      301 tgcttcaggc taaacaattt gttcagcttt caaattcaac gcggtgttct cggtttgtat
      361 tacttacatt tacttcaaat
//
LOCUS       DAFLWQ010000279          367 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.293, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000279 DAFLWQ010000000
VERSION     DAFLWQ010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.293"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            57..>367
                     /locus_tag="L1V16_003171"
     CDS             57..>367
                     /locus_tag="L1V16_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBN1277410.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QT"
BASE COUNT          133 a           56 c           85 g           93 t
ORIGIN      
        1 taagctattg acagttaaaa cgttgattca agcaaggtta gcaaacggag gaaactatgg
       61 caagacgaag aagaaaatca agagggaaaa aaatatttct gattatttta gcagttctta
      121 tcgtattagt attagcaatt gtaggagtag gagcaaaatt atatctggat ctctcacatt
      181 ctattgagaa aacttacgaa tcagtggaac gaacccaagg agaacgaacg aaaccagttg
      241 atctggacaa acaagaatct ttctctgttc tattgatggg gattgatact ggagatttag
      301 gtcgggtcga tcaaggaaga tcagatacga tgatggttgc cacagtcagt cctgaagaca
      361 aacagac
//
LOCUS       DAFLWQ010000280          366 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.294, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000280 DAFLWQ010000000
VERSION     DAFLWQ010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.294"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            80..>366
                     /locus_tag="L1V16_003172"
     CDS             80..>366
                     /locus_tag="L1V16_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBN1277411.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCR"
BASE COUNT          129 a           59 c           76 g          102 t
ORIGIN      
        1 tttaggtatt aaaaaacata tcgttctcta gtatgattaa atcacgacaa aataaacaac
       61 tgagaggacg atatgctata tgaatgattc tatcaaaaaa atgctgcgat taatagagaa
      121 agatttgatg attacagagg tctcttacga gacctttcag aagaaaaaga cgttgatcgt
      181 cgatgctgtt ttctcacctg ctccccatac ctgtagaaat tgtggttcta ctgtggtaga
      241 tggaaacggg aaagtaattg tagtgaaaaa tgggaagaag gaaacgattg tccgctttga
      301 acaatacaat cacatgcctt tggttatgcg cttaaaaaag cagcgctata cctgtaaaaa
      361 ctgtcg
//
LOCUS       DAFLWQ010000281          349 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.295, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000281 DAFLWQ010000000
VERSION     DAFLWQ010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.295"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(44..>349)
                     /locus_tag="L1V16_003173"
     CDS             complement(44..>349)
                     /locus_tag="L1V16_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1277412.1"
                     /translation="TIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQF
                     ETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT           98 a           86 c           64 g          101 t
ORIGIN      
        1 atcctcggat ctgattttct ccggcagaag cacaatcatt caattacgct gcctctccag
       61 aggtatcaga tccgcgctca ttatcaagga ttcgcttcgc caatctctgt tgtcgaattt
      121 ggatcggtgt ttcatacgcc aacgtgccat gtaagcgtag atagttccac caatgcacat
      181 aatcaaacaa ttctagacgt agctgtgcca gtgtctcaaa ttggtattga tgcacgaatt
      241 ctactttgac agatttatag gttgattcca caacggcatt atcatacgga caacccttcc
      301 tactcaatga acgagtaatt ccaaaaccat tcagaatctc atgaatggt
//
LOCUS       DAFLWQ010000282          331 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.297, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000282 DAFLWQ010000000
VERSION     DAFLWQ010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.297"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
BASE COUNT           95 a           87 c           48 g          101 t
ORIGIN      
        1 atactaaacc ccaagttaaa cccctccttc gcgctgtcgc taataaaaag agtgtaaacc
       61 tttctgttac tctttgacaa agagtaacat tttcctaatt gtgacatggc tgtcacaatt
      121 ccaaatgctc tccgagggta ttcgctgtca caagtgacaa cgaaaaaagg agccgaaagc
      181 gtgtcacgct ctcaactcct tttacgcttt attttgcttc acgcaaaata atcgcttatc
      241 gtaaactcac gtcattaaac attgacgtaa atttactctc actcatctga cttttcttat
      301 tcggtatcac ttctctgtca cgtccaaacc c
//
LOCUS       DAFLWQ010000283          327 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.298, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000283 DAFLWQ010000000
VERSION     DAFLWQ010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.298"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..>327
                     /locus_tag="L1V16_003174"
     CDS             <1..>327
                     /locus_tag="L1V16_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HBN1277413.1"
                     /translation="YVRRFRETTVFEDIFAYILEQAVKAGFVTEDNLYLDSTHIKANA
                     NKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPE
                     SGYYVKG"
BASE COUNT          122 a           51 c           74 g           80 t
ORIGIN      
        1 ttatgttcgc cgatttagag aaacgacggt gtttgaggat atttttgcct atattttaga
       61 acaagcagtt aaagcaggtt ttgtaacaga ggataatttg tatctggatt ctacccacat
      121 caaagctaac gccaataaac ataagtttac gaaagaaatg acccatgatg aagcgaaagc
      181 ctatcaggat gaattagaag atgagatcaa tcgtcaacga atagaggctg gaaaacgccc
      241 ttttactttg gacttagaaa aggaagtgaa gctgaaagaa agaaaaataa gtaaagctga
      301 tccggaaagc ggctactacg tcaaagg
//
LOCUS       DAFLWQ010000284          321 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.299, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000284 DAFLWQ010000000
VERSION     DAFLWQ010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.299"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..>321
                     /locus_tag="L1V16_003175"
     CDS             <1..>321
                     /locus_tag="L1V16_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBN1277414.1"
                     /translation="TQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTK
                     TEHRTVKYLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFG
                     FSVST"
BASE COUNT          107 a           69 c           63 g           82 t
ORIGIN      
        1 acgcaagcag cctatgcttt cttaaaacga ctccataaac agtttggtga gccgaaagca
       61 attgtgaccg ataaagcacc ttctcttggc tccgccttta gaaagttaca gagtgtgggt
      121 ttatatacta agacagagca ccgaactgtg aagtatctta acaatttaat agaacaagac
      181 catcgaccta ttaaacgacg aaataaattt tatcaaagtc tccgtacagc ctcttccacg
      241 attaagggca tggagaccat tcgaggaata tataaaaaga accgaagaaa tggaacgctc
      301 ttcggctttt cggtgtctac t
//
LOCUS       DAFLWQ010000285          321 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.300, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000285 DAFLWQ010000000
VERSION     DAFLWQ010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.300"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(69..321)
                     /locus_tag="L1V16_003176"
                     /pseudo
     CDS             complement(69..321)
                     /locus_tag="L1V16_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT           79 a           78 c           51 g          113 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat g
//
LOCUS       DAFLWQ010000286          309 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.301, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000286 DAFLWQ010000000
VERSION     DAFLWQ010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.301"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            1..309
                     /locus_tag="L1V16_003177"
                     /pseudo
     CDS             1..309
                     /locus_tag="L1V16_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          122 a           61 c           59 g           67 t
ORIGIN      
        1 attcaaaaga attcaaacaa caaatcgtcg atctctatct cgctggtaag cctcgcgcag
       61 aaattattcg agagtatgag cttacgcctt cttctttcga taaatggatg aagcaagcac
      121 aatcaacggg ctcattcaaa gaaagagaca acttaacacc agaacaagca gaattgatcg
      181 cactaagaaa gaaaaataag caactcgaaa tggagaatga tattttaaag caagcggcgc
      241 tgatattcgg acgaaaagac aagtaattga tgccaacaag cataaatatt ccatatcagc
      301 gatgtgcaa
//
LOCUS       DAFLWQ010000287          301 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.302, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000287 DAFLWQ010000000
VERSION     DAFLWQ010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.302"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..135
                     /locus_tag="L1V16_003178"
     CDS             <1..135
                     /locus_tag="L1V16_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucocin A/sakacin P family class II
                     bacteriocin"
                     /protein_id="HBN1277415.1"
                     /translation="DAATYYGNGLYCNKEKCWVNWGQSWSEGLKRWGDNLFGSFSGGR
                     "
BASE COUNT          117 a           36 c           57 g           91 t
ORIGIN      
        1 gacgcagcta cttactatgg aaatggtctt tattgtaaca aagaaaaatg ttgggtaaat
       61 tggggacaat catggtcaga agggttaaaa cgttggggag ataatctttt tggtagtttt
      121 agtggaggac gataatgact tcaataaaca ttgatcacac aaaaaaagtc atacatgaat
      181 tatacaatag tttaatgaca cgacctaatc agacgaaagc attattagat attactgatg
      241 ttttatttca ggtatataaa aaaattgata cagcaaaata tcctgaaatt cttgtaaata
      301 a
//
LOCUS       DAFLWQ010000288          285 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.303, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000288 DAFLWQ010000000
VERSION     DAFLWQ010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.303"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
BASE COUNT          114 a           35 c           37 g           99 t
ORIGIN      
        1 tactataaaa aagcaaaata ttacctccta attaaatatt aaataccgaa aaaattatgt
       61 ttagataata ccatagttaa gtttttcctt gtgatgtttt tcgtaaaaag atattttagc
      121 agcattatcg ttacagtgca tagttaccat cggcgttatg actatataaa gtatactttc
      181 gttgatccag aaaggtatat agattaaaat aagttaccta aaaaggacaa atacaaattt
      241 tattatctta ttcacagtaa gaagataatt ttaagattgc gaaat
//
LOCUS       DAFLWQ010000289          281 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.305, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000289 DAFLWQ010000000
VERSION     DAFLWQ010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.305"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            28..>281
                     /locus_tag="L1V16_003179"
     CDS             28..>281
                     /locus_tag="L1V16_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1277416.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDT"
BASE COUNT           84 a           53 c           56 g           88 t
ORIGIN      
        1 tgaaaacgaa tgcaaggagt gatagctatg atgtctaaaa acaatacgaa tggtagaaat
       61 caatttgcga tgcttacgat tgatgatcta gttcctcaag atcatctcgt tcgaaagatt
      121 gatgccgcgc ttgattttga atttatttat ccaatcgtcg aagccactta ctccgattta
      181 ggtcgcccaa gtatcgatcc agtgattctg atcaaattgg tgtttattca gtatttattc
      241 ggtatccgtt ccatgcgaca aaccattaag gaagtcgata c
//
LOCUS       DAFLWQ010000290          275 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.306, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000290 DAFLWQ010000000
VERSION     DAFLWQ010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.306"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..>275
                     /locus_tag="L1V16_003180"
     CDS             <1..>275
                     /locus_tag="L1V16_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1277417.1"
                     /translation="FICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLVMD
                     MNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTS"
BASE COUNT           80 a           65 c           48 g           82 t
ORIGIN      
        1 tttatttgtg ttgatgggac aaccaatcag ctatttacga tccttgaaga tcgcagactt
       61 tacaaactaa ctcaatactt cctgcgcttt cctagaaagg cccgtttaaa ggtcaagtac
      121 ctagtgatgg acatgaatgc cagctattgt cagttgctta aaacagtctt tccaaatgcg
      181 gagatcgtaa ctgaccgctt tcatattgtc caacacatca atcgcagctt caatcaatta
      241 cgtgtccaga tcatgaatcg ttttcgaacc tcaca
//
LOCUS       DAFLWQ010000291          272 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.307, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000291 DAFLWQ010000000
VERSION     DAFLWQ010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..272
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.307"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..>272
                     /locus_tag="L1V16_003181"
     CDS             <1..>272
                     /locus_tag="L1V16_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1277418.1"
                     /translation="TMKKEFPIPISWTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGV
                     GGGALQEGRFIEGFSHPEMGHMLVVPHPKDDFAGSCPFHGNCLEGMA"
BASE COUNT           66 a           56 c           77 g           73 t
ORIGIN      
        1 accatgaaaa aagaatttcc gatcccgatt tcttggacaa cagatgtcaa tgcggctgcc
       61 tatggtgagt atgtcttcgg cagtggcaaa ggattgagca gtgtcgttta ctatacgatc
      121 ggtacgggtg ttggcggcgg tgccttacaa gaagggcgct ttatcgaagg gtttagtcat
      181 ccagaaatgg ggcatatgct cgtcgtccct catccaaaag atgactttgc tggcagctgt
      241 ccatttcatg gcaactgttt agaagggatg gc
//
LOCUS       DAFLWQ010000292          268 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.308, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000292 DAFLWQ010000000
VERSION     DAFLWQ010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..268
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.308"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(36..>268)
                     /locus_tag="L1V16_003182"
     CDS             complement(36..>268)
                     /locus_tag="L1V16_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1277419.1"
                     /translation="LKNLPETLDAQLRTKLQNLLTYEEGIYNAMIYPYSNGKIEAKIP
                     HIKTLKRLSYGFKSFENMKIRIFLINQLIQVK"
BASE COUNT           79 a           39 c           47 g          103 t
ORIGIN      
        1 atagaaggac tgaccttctg tctcagattt ttttgttatt tcacttgaat caattgattg
       61 atcaaaaaaa tcctgatttt catgttctca aatgatttaa atccataaga taatcgtttc
      121 agtgtcttga tatggggaat cttggcctct attttgccat tagaatacgg gtaaatcata
      181 gcattgtaaa taccttcttc atacgttaaa aggttttgaa gtttcgtgcg aagttgtgca
      241 tcaagtgttt caggaagatt ttttaata
//
LOCUS       DAFLWQ010000293          244 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.311, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000293 DAFLWQ010000000
VERSION     DAFLWQ010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..244
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.311"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..>244)
                     /locus_tag="L1V16_003183"
     CDS             complement(<1..>244)
                     /locus_tag="L1V16_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBN1277420.1"
                     /translation="NNGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTL
                     IEDIHRDEILFTDLDDTYLLIEFPTLEVPLYAERLFF"
BASE COUNT           70 a           48 c           44 g           82 t
ORIGIN      
        1 caaaaaaaag ccgttctgca tataacggca cttccagtgt cggaaattcg atcagaagat
       61 atgtatcatc taaatctgta aataaaattt catctcggtg gatgtcttcg atgagcgttc
      121 cggtaatacg tacttcttgt ccttccaata acgtcaaagg caactgtctt ttctctaatt
      181 cggcttgtaa cgaagcgact agagaaatga cttgtgattt ttcattgctg tattttccat
      241 tatt
//
LOCUS       DAFLWQ010000294          241 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.314, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000294 DAFLWQ010000000
VERSION     DAFLWQ010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.314"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(<1..220)
                     /locus_tag="L1V16_003184"
     CDS             complement(<1..220)
                     /locus_tag="L1V16_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1277421.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFP"
BASE COUNT           63 a           45 c           46 g           87 t
ORIGIN      
        1 caggaaaaat gatttcggtt ctcccacaac gtcgcttatt ttctttgtat tgttcaaagt
       61 attcaagtgc tgttccacca catttgagaa agttatagac attgtaaatt gtttggcgtc
      121 cacgtttaag ctgcttcgca acgatagcaa ccggagtttc ttgatgaaaa tatgcttcta
      181 tcattacaag ctcgtttggt gtaagatggg tataagtcat ttatgttcac tctccttgta
      241 t
//
LOCUS       DAFLWQ010000295          233 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.denovo.316, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000295 DAFLWQ010000000
VERSION     DAFLWQ010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..233
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.denovo.316"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
BASE COUNT           79 a           35 c           45 g           74 t
ORIGIN      
        1 tgagaaaaag catggaatgc gctgcatcag gtatcgaggc ttagaaaaaa atcaggtgca
       61 tacgatgctt gtttttgccg aaatgagtct gaaaaaattg gtcacttagc agtgggagca
      121 tatgtcttca tattttttat tatacaaaaa tagacaaaag tatcagtcta cactcttagt
      181 aaagaggaaa ctgatacttt tgtctacagt atgatatttc ttacatctac ttt
//
LOCUS       DAFLWQ010000296        52090 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.guided.008, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000296 DAFLWQ010000000
VERSION     DAFLWQ010000296.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52090
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.guided.008"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(39..1439)
                     /locus_tag="L1V16_003185"
     CDS             complement(39..1439)
                     /locus_tag="L1V16_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HBN1277422.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            1657..3318
                     /locus_tag="L1V16_003186"
     CDS             1657..3318
                     /locus_tag="L1V16_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBN1277423.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            3275..3973
                     /locus_tag="L1V16_003187"
     CDS             3275..3973
                     /locus_tag="L1V16_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBN1277424.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            3989..4510
                     /locus_tag="L1V16_003188"
                     /pseudo
     CDS             3989..4510
                     /locus_tag="L1V16_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
     gene            4767..4955
                     /locus_tag="L1V16_003189"
                     /pseudo
     CDS             4767..4955
                     /locus_tag="L1V16_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604486.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            5001..5966
                     /locus_tag="L1V16_003190"
     CDS             5001..5966
                     /locus_tag="L1V16_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1277425.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKNLTLKAKGLLSQMLSLPEDWD
                     YTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDAKGKMADMVYTIYEQPVLENP
                     VLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLSKKEKIITDGQSTHSIPIPSP
                     TPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEYAYLIQDRSIDREQLDEIVDL
                     MLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRFVLDCLRENTTKVRNIKQYLR
                     AMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYSCGEGESL"
     gene            5988..6200
                     /locus_tag="L1V16_003191"
     CDS             5988..6200
                     /locus_tag="L1V16_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBN1277426.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            6275..6751
                     /locus_tag="L1V16_003192"
     CDS             6275..6751
                     /locus_tag="L1V16_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HBN1277427.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            6748..8556
                     /locus_tag="L1V16_003193"
     CDS             6748..8556
                     /locus_tag="L1V16_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBN1277428.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            8633..8848
                     /locus_tag="L1V16_003194"
     CDS             8633..8848
                     /locus_tag="L1V16_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HBN1277429.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            8940..9803
                     /locus_tag="L1V16_003195"
     CDS             8940..9803
                     /locus_tag="L1V16_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277430.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            9840..10376
                     /locus_tag="L1V16_003196"
     CDS             9840..10376
                     /locus_tag="L1V16_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HBN1277431.1"
                     /translation="MSTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVERL
                     ASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTRGN
                     AEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFARQK
                     TPGWDVWGNEVECDLILT"
     gene            10390..10812
                     /locus_tag="L1V16_003197"
     CDS             10390..10812
                     /locus_tag="L1V16_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBN1277432.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            10742..13141
                     /locus_tag="L1V16_003198"
     CDS             10742..13141
                     /locus_tag="L1V16_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBN1277433.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            13173..15164
                     /locus_tag="L1V16_003199"
     CDS             13173..15164
                     /locus_tag="L1V16_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBN1277434.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     DRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            15187..15438
                     /locus_tag="L1V16_003200"
     CDS             15187..15438
                     /locus_tag="L1V16_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HBN1277435.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            15428..16657
                     /locus_tag="L1V16_003201"
     CDS             15428..16657
                     /locus_tag="L1V16_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HBN1277436.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            16654..18735
                     /locus_tag="L1V16_003202"
     CDS             16654..18735
                     /locus_tag="L1V16_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBN1277437.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            18884..22804
                     /locus_tag="L1V16_003203"
     CDS             18884..22804
                     /locus_tag="L1V16_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HBN1277438.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKID
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLTERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            22805..23749
                     /locus_tag="L1V16_003204"
     CDS             22805..23749
                     /locus_tag="L1V16_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277439.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            23753..23956
                     /locus_tag="L1V16_003205"
     CDS             23753..23956
                     /locus_tag="L1V16_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HBN1277440.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMLVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(24256..24492)
                     /locus_tag="L1V16_003206"
     CDS             complement(24256..24492)
                     /locus_tag="L1V16_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1277441.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(24675..25061)
                     /locus_tag="L1V16_003207"
     CDS             complement(24675..25061)
                     /locus_tag="L1V16_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HBN1277442.1"
                     /translation="MDARAMSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECI
                     CVQSISYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAA
                     CSKRMRRRKEAERQRKRYWKPTHLEL"
     gene            complement(25043..26371)
                     /locus_tag="L1V16_003208"
     CDS             complement(25043..26371)
                     /locus_tag="L1V16_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBN1277443.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(26332..26661)
                     /gene="mobC"
                     /locus_tag="L1V16_003209"
     CDS             complement(26332..26661)
                     /gene="mobC"
                     /locus_tag="L1V16_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBN1277444.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(26919..27290)
                     /locus_tag="L1V16_003210"
     CDS             complement(26919..27290)
                     /locus_tag="L1V16_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1277445.1"
                     /translation="MANIEDCPGFETFGADVKAARQAKRVSRKAMAEKINIDWRYLAN
                     IENDGAIPSLPVVIQLIKACGLPVERYFNPEIMREESELRQRVSHKLKLCPEEYLPII
                     EGAIDSAILIEKPKKNETEDV"
     gene            27435..27620
                     /locus_tag="L1V16_003211"
     CDS             27435..27620
                     /locus_tag="L1V16_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBN1277446.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            27778..27945
                     /locus_tag="L1V16_003212"
     CDS             27778..27945
                     /locus_tag="L1V16_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277447.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            28563..29222
                     /gene="vanR"
                     /locus_tag="L1V16_003213"
     CDS             28563..29222
                     /gene="vanR"
                     /locus_tag="L1V16_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HBN1277448.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            29225..30568
                     /gene="vanS"
                     /locus_tag="L1V16_003214"
     CDS             29225..30568
                     /gene="vanS"
                     /locus_tag="L1V16_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBN1277449.1"
                     /translation="MERKGIFIKVFSYTIIALLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPDFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQAQSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
     gene            30739..31545
                     /gene="vanY"
                     /locus_tag="L1V16_003215"
     CDS             30739..31545
                     /gene="vanY"
                     /locus_tag="L1V16_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-B/VanY-G family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HBN1277450.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGRR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            31563..32390
                     /gene="vanW"
                     /locus_tag="L1V16_003216"
     CDS             31563..32390
                     /gene="vanW"
                     /locus_tag="L1V16_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance accessory protein
                     VanW-B"
                     /protein_id="HBN1277451.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGEPFSFWWLVRHA
                     DKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGHEVKEFPEPN
                     SDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVSADKEPQALYKITNG
                     SIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPESVDIQEENQ"
     gene            32387..33358
                     /locus_tag="L1V16_003217"
     CDS             32387..33358
                     /locus_tag="L1V16_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HBN1277452.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVGHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            33351..34379
                     /gene="vanB"
                     /locus_tag="L1V16_003218"
     CDS             33351..34379
                     /gene="vanB"
                     /locus_tag="L1V16_003218"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HBN1277453.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGTFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            34385..34993
                     /locus_tag="L1V16_003219"
     CDS             34385..34993
                     /locus_tag="L1V16_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HBN1277454.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(35059..35232)
                     /locus_tag="L1V16_003220"
     CDS             complement(35059..35232)
                     /locus_tag="L1V16_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277455.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
     gene            35581..36012
                     /locus_tag="L1V16_003221"
     CDS             35581..36012
                     /locus_tag="L1V16_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1277456.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
     gene            36019..36252
                     /locus_tag="L1V16_003222"
     CDS             36019..36252
                     /locus_tag="L1V16_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1277457.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            36676..36876
                     /locus_tag="L1V16_003223"
     CDS             36676..36876
                     /locus_tag="L1V16_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBN1277458.1"
                     /translation="MNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVIM
                     NGNRIQIKRKQFEKIIDTLDTI"
     gene            36960..38153
                     /locus_tag="L1V16_003224"
     CDS             36960..38153
                     /locus_tag="L1V16_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1277459.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            38319..39230
                     /locus_tag="L1V16_003225"
                     /pseudo
     CDS             38319..39230
                     /locus_tag="L1V16_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
     gene            39537..40697
                     /locus_tag="L1V16_003226"
     CDS             39537..40697
                     /locus_tag="L1V16_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBN1277460.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            40815..42674
                     /locus_tag="L1V16_003227"
     CDS             40815..42674
                     /locus_tag="L1V16_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBN1277461.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            42784..43218
                     /locus_tag="L1V16_003228"
     CDS             42784..43218
                     /locus_tag="L1V16_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277462.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(43477..43638)
                     /locus_tag="L1V16_003229"
     CDS             complement(43477..43638)
                     /locus_tag="L1V16_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277463.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(43657..44679)
                     /locus_tag="L1V16_003230"
     CDS             complement(43657..44679)
                     /locus_tag="L1V16_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HBN1277464.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            44807..45160
                     /locus_tag="L1V16_003231"
     CDS             44807..45160
                     /locus_tag="L1V16_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBN1277465.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            45172..46338
                     /locus_tag="L1V16_003232"
     CDS             45172..46338
                     /locus_tag="L1V16_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1277466.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(46430..47050)
                     /locus_tag="L1V16_003233"
     CDS             complement(46430..47050)
                     /locus_tag="L1V16_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBN1277467.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(47222..47518)
                     /locus_tag="L1V16_003234"
     CDS             complement(47222..47518)
                     /locus_tag="L1V16_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBN1277468.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            47722..48372
                     /locus_tag="L1V16_003235"
     CDS             47722..48372
                     /locus_tag="L1V16_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBN1277469.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            48388..50115
                     /locus_tag="L1V16_003236"
     CDS             48388..50115
                     /locus_tag="L1V16_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1277470.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            50112..52004
                     /locus_tag="L1V16_003237"
     CDS             50112..52004
                     /locus_tag="L1V16_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1277471.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
BASE COUNT        14503 a        11953 c        13072 g        12562 t
ORIGIN      
        1 cttatttctt gaagctgacc acttctgtca caacctcttt aagaatgatg gatagaaata
       61 cgtttaggat aagttttttt agatgcactt tgttcgattt cctctaaaga tttcccacga
      121 gtttctggta cgatctcttg aataaataaa acccctaaaa agcagatgat cccaaaaatg
      181 ccgaaaacga tttcttgaga catagaagca gtcatcacag gaaaaagcaa gccaactagg
      241 aaagaaccaa tccaattaaa agaagaggct aggccagatg ctcgcccgcg gacagctagt
      301 gggaatattt cgcctatgat tacccatgtc agtggagccc atgtgcaaga ataaaatgcg
      361 acataaatac ataaaaacaa gagaatcaac aacgaatttg tatgagcatc cagtacagtt
      421 cctaaaacag ctggtaggat gaatgaaagt cccatcacgc taccgcctat tttcaataaa
      481 gttcgccgat tgaacttgtc tgcaataacc aaaaagagca aagaaccagc aactaaaatg
      541 attccttgga tgatcggcca catcaatgca tcgctcgctg catgcccagt cgctttttct
      601 acgatcagcg gaatatagta aaaaatagca ttagctcctt gaaattgctg gaatactgct
      661 acaccaatac cggcaatgac taaggaacga tatttttcta aaaacaaagt atgccaagaa
      721 gttccggttg tcttttcttg tttgacattc agctggattt gttcgaattc ctgttcagct
      781 tcttttggtg tccgaatata gttcaatact ctttttgcct cttccaagcg gccagattgc
      841 ataagaaaac gcggtgactc tggtagagct aaaacaccga aaaataaaat cagcgcgggg
      901 acagcagcga gccctaacat cacgcgccaa gccatcgttt caggcaacac ttttagcaaa
      961 taatctgcaa cataggaaag gagcatgcca gaagcaatca tcacttgatt gatccctgac
     1021 aatcttcccc ttagtctagc aggagccatt tcagacatat aagcaggaac tagggcagat
     1081 gcagcgccaa cagctaaacc tagaagaatc cttgctgcaa tcagaaaata agaaccattg
     1141 tgaggggcag atgcagaaag gacagaacca gccataaaaa taagtgcaga aagaagaatc
     1201 atttttcgtc gtccaagctt atcagaaaga agaccagata aagagccgcc aaggatcgca
     1261 cctaacatga ccgaagacgt gatccatcct atcaaagaag ctttacctgc caaaccccaa
     1321 tcatgctgta aaaaaggtaa ggcgccggtc ataacaccaa tatcatatcc aaatagaatg
     1381 ccgccaaatg cgccaaaaaa ataaataaac gatgaggaaa cttttttttc ttttttcata
     1441 agtattctct ccttctagaa tttcgagaag gcggttgatc agattttgta agcaatttca
     1501 ttttataact tatgtacgta caaaacaagt gttttttatt gtattcttgt aaataaccgc
     1561 ttgacatgta cgtacaaaag tatacaataa tcattgtaag cgctactaaa aagacggttt
     1621 gatcaggttt gacgagaagg agggagttaa atcattatga aggaagtaaa tgcgcaaagt
     1681 atgttagatg tcatagatgg tcgtacatct ttagggattg agtttggatc aactaggatc
     1741 aaagctgtat tgattgattc atcttttact cctattgccg ctggtagtta tgagtgggaa
     1801 aacaaactag aaaatggtat ctggacctat tcattagaag atatttggaa aggactgcgc
     1861 gtcagttacc gaaaaatggc agcagaagta ttcgaaatct atggcgagaa tcttacgaca
     1921 atcgggtcga ttgggttcag tgcaatgatg cacggttatc tagcatttga tagcaaggaa
     1981 cagttactag taccatttcg tacttggcga aatacaatca ctgaagaagc agaacgaata
     2041 ttaacggaaa aatttcaata caatattccg cagagatgga gtatcgctca tttgtatcaa
     2101 tctattttga ataaagaaga acatgtgaaa gaaattaatt ttttgacaac gcttgcaggt
     2161 tatgtccatt ggcagcttac tggtgagaaa gtactaggcg taggagatgc atcaggcatg
     2221 tttcctatcg atccttcaac gaaaacctac catcaagaaa tgaaaaatat ttttggtcag
     2281 ttaatcgaaa aagcgcacgt agcgattgac ttggatcaca ttttgcctaa agttctagta
     2341 gcaggagaag aagctggcaa gttaagcgaa tcaggggctt atctgatcga ccctacggga
     2401 aatttgagac caggaatccc ggtttgtccg ccagaagggg atgcaggaac cggtatggtc
     2461 gctacgaaca gtgtagccaa acggacaggg aacatttcgg ctggtacttc cgccttcgct
     2521 atgatcgtat tagaaaaaga actagaaaat gtccatccgg aaatcgacat ggtcactaca
     2581 ccttcaggag aactagtagg catggttcat acgaataact gctcttcgga tatcaatgct
     2641 tgggtcagta tttttgaaga atttaccaat tctttgggta tggagataag cagagataaa
     2701 ttattcacgg tattattcaa caaagcgcta gaaggcgata cggattgcgg gggattactt
     2761 tcttatggtt atttttccgg tgaaaacatt acaggagtaa atgaaggaag gccattattt
     2821 gtacgtacac caggtagccg ttttgattta gcgaatttca tgcggatcca tttagccagt
     2881 gcttttggtg caatgagaat cggaatggat atattgaaat ctgagaatgt ccaaattgat
     2941 cgtttagtgg ggcatggggg gatttttaaa acaccagaag ttggacagcg gattctagca
     3001 tctgctatgg aggcaccagt tacagtgatg gacacagccg gagaaggtgg agcgtgggga
     3061 atcgcgttat tagcagccta tatgatggat cgacatggga agtctttaga aaacttcttg
     3121 gcagaagacg tgtttggaca agaccaagga atcaccatca caccttcagc agaagaaata
     3181 gcaggctatc agatatttat gagacgttac cgtgagggga tcgacattga aaaaacagcg
     3241 attcatcaat tgcaagaaaa aggagtgata gaaaatgctg gaacaactga aagaagaagt
     3301 ataccaagca aatcttgact tgcctaaaca cggactcgtc aaatatacat ggggaaatgt
     3361 gagcgctttt gatcctgaaa cacgatattt cgttatcaaa cctagcggag tcagttatga
     3421 agagatgaca gcagacgaca tggtcgttgt ggacttggac aatcatatca ttgaaggtaa
     3481 actcaatccc tcttcggata cgcctactca tgctgtttta tatcgttcat ttcctcaaat
     3541 cggaggaatc gtccatactc actcgacatg ggcgacgatc tgggcacaag caggattgga
     3601 tgttcctgcg atggggacga cgcatgcaga tactttttat ggatcggtac cttgtgctcg
     3661 atttttgaca caacaggaaa tcgacagcgg gtacgaatat gaaacaggaa aagttatcat
     3721 agaaacattc aaagaacgca aaattgatcc cttagcaatt ccaggggtac ttttacacgg
     3781 acacggtcca tttacttggg ggaaagatgc gcaaagtgcg gtaatgaacg cagtcgtact
     3841 agatgaagta tgcaagatga atttatttac cagacagctc aattcatttt cagaagagct
     3901 gcctcaacgg attttagata aacattattt acgaaaacac ggaaaaaatg cgtattacgg
     3961 acaaaacaaa taaaaggagt ggctaattat gttgaatatt ggagaaaaag aattttggtt
     4021 tgttgtagga tcacagcatt tatatgggga agaagcactg cgagaagtaa agaaacatgc
     4081 acaagaaatg gtcgatgaac tgaatgaaaa tggccaattg ccttatccaa tccgccttca
     4141 agaattagca gttactgctg atacgatcac aaaaatcatg aaagaggtca attatcgaga
     4201 agaagtagca ggtgtgatca cttggatgca tactttctca ccagcaaaaa tgtggatccg
     4261 cgggacaaag cttctacaaa aaccattgct tcatttagct acgcaatata acgaaagcat
     4321 tccttggaaa acgatcgata tggatttcat gaatttaaat caatccgctc atggtgaccg
     4381 cgaatatggg ttcatcaatg ctcgattaaa taaacaaaat aaaatcgtcg ttggctactg
     4441 gaaacgacct gagatccaaa aagagattgc tgattggatg gatgttgcag tagcctataa
     4501 tgaaagtttt attccaaaaa tttaggttat cgctgaaagc cccggaaata cgggcatttc
     4561 gcaggatatg agaactcaat ttactaccaa tttactactt tcggattgag ccgcatatat
     4621 gctgaaccat actgctaata cccgccaccc caaatacggc acatcataaa ttgaatacga
     4681 caccgtaaac gcggcgttcc tctttcccgt catgggagaa caggacgccg cttttttatg
     4741 cccaaataga gaaaggaggc gacgccatgc tatttacttc cggccctgac cgggcgtttg
     4801 aacggctgat gcaggaaaag cccggtttcg atcactacga cggcggcggg gcggacgcgc
     4861 cggaggattg cggcacctgc cgattttacc gcccggattg gaaatatcaa ttctgccagt
     4921 ttgcagagtg tccctatcag ccgggcaagc tgaccgacta tgcagcggtc aaattcacag
     4981 tgaaaggagc gaacaacgct atggcagttt tccgtgtgga aaagaacaaa ggctatacgg
     5041 tgatgtcaaa tcaccacctg cggaataaga acctgacctt aaaggccaag ggcctgctgt
     5101 cgcagatgtt gtccttgccg gaggattggg actataccct aaaaggactg tcctatatca
     5161 accgggaaag catcgacgcg atcaggacag cggtatggga gcttgaaaaa gctggatata
     5221 tccggcgtga gcagggccgt gacgcaaaag gcaaaatggc cgatatggtc tataccatct
     5281 acgaacagcc ggtattggaa aacccggtat tggaaaatcc aacatcggat aacccggtgt
     5341 tggaaaatcc gacatcggat aatccggcgt cggaaaatcc aacgcaatta aataaagaag
     5401 tacaaagaac tgacttatca aaaaaagaaa aaataattac agatggacaa agtacccatt
     5461 ccattcctat cccatccccg acccctgccc ctatggaggg cgaggcagcg gctacgccgc
     5521 cggaacggaa aaggacagga aaggatgagg ctgtacggat ttatcgggaa atcattttgg
     5581 agaacatcga gtatgcctat ctcattcagg acaggagcat tgaccgtgaa cagcttgacg
     5641 aaatcgtaga cctgatgctg gaaaccgtct gcaccgcccg aaagacaatc cgtgtcgccg
     5701 gggacgacta ccctgccgag ctggtgaaat ccaagtacat gaagctgacc ggcgaacata
     5761 tccgctttgt ccttgactgt ctgcgggaga acacaacgaa agtccgcaat atcaaacaat
     5821 acctgcgggc tatgctgttc aacgccccca gcaccatttc caactactac acggcccttg
     5881 tcgcgcacga catggcacag cccgattggg gaaagcctaa atccggcctg ccggactatt
     5941 cctgcggcga gggcgaaagc ctgtaacgag aaaaggagga cgaccctatg aagcagggcg
     6001 cattgatttt tgacgagcga acagaccgtt acgacatccg ctttgatctg gccgactatt
     6061 acggcggcct gcattgcggg gagtgtttcg acgtgatgat cggcggcaaa tggaggccca
     6121 cccgcattga aatggccgaa aactggtatc ttgtcggcat ccgggccgac gacctttccg
     6181 gcctgcgggt gcggatttga cctatatcta cctgcggcgt ctggtggttc cgccttagac
     6241 gccgcttttg actttctgac aaggagggat gcgattgcag gaagaagtta ctcaaaagac
     6301 cattgccctg tccatgaaaa cgggcaagct cacggctcaa gtgctgcaag cggcgctgaa
     6361 aaagtacctg caacaccggg ccaagggcaa aaacacgctg caccacggcc agcagagcct
     6421 aaagcagctt aaaaagcatg gggctgatct ctccaacatt gagatcaccg aggccaacat
     6481 tggagcgttc aagccatgcg ccaagaaata cggcgtggat tttaccttac gaaaagataa
     6541 gaccacccag ccgccccact acgttgtgat tttcaaggcc aaggatgcag ataaccttga
     6601 tctggcgttt cgggagttta ccgccaagac gctttccaag gagcagcggc cctctatccg
     6661 caaggttttg tccgctgtga agcaaaaggc ggcggcccag accaagcagc gggccaagga
     6721 gaaaatcaag gaaagggggc tggaactgtg aagcctgacg taaagaaatt gctgatcctg
     6781 aacctcccgt atctgatttt tgtgtacctg tttgcgaaat gcggggaggc gtaccggctg
     6841 gccgctggtg ctgacctgtc ggggaagctc ctgcattttg cggatggttt tgcggcggct
     6901 tttgccaacc cgctgccaag cctgcacctg tttgacctgt gtatcggtat cgccggtgcc
     6961 gtgatcgtgc ggctggtggt gtactgcaag agcaagaacg tgaagaaata ccgcaaaggc
     7021 atggagtatg gcagcgcccg ctgggggacg gccaaagaca tagcgcctta catcgacccc
     7081 aagtttgaaa ataatatcct gctcacccaa acggaacggc ttaccatgac cggcaggccc
     7141 aaagacccca agacagcgcg gaataaaaac gtgctggtga tcggtggcag cggttcaggg
     7201 aaaacgagat ttttcgtgaa acccaacctg atgcaatgct ttccgaccac ggactatccg
     7261 acttcgtttg tggtgacaga tccgaaaggc actttggttc tggaaaccgg caggatgttc
     7321 cagcaggcgg gctaccgcat taaaatcctg aataccatta acttttccaa gtccatgaag
     7381 tacaacccct ttgtctacat ccattcggaa aaggacgtgc taaagctggt aaataccctg
     7441 atttccaaca ccaagggcga gggggaaaag tcagcggagg atttttgggt gaagtcggaa
     7501 cggttgtttt attcggccct gatcggctat atctggtacg aggccccagc ggaggaaatg
     7561 aacttctcaa cgctgctgga aatgataaac gccagtgaag cccgcgagga cgacccggag
     7621 tttcaaagcc ccgtcgatct catgtttgag cgtttggagc agaaagaccc cgaccatttt
     7681 gcggtgcgcc agtacaagaa attcctgctg tccgcaggca agacccgttc ttccatcctg
     7741 atttcatgcg gtgccagact tgcgcccttt gacatccggg aggtacgcga gctgatggag
     7801 gacgacgaaa tggagctgga caccatcggg gacgaaaaga cggtgctgta tctcattatg
     7861 agcgatacgg acacgacctt taatttcatt ctggctatgc tccaaagcca gctaatcaac
     7921 ctgctttgtg accgggctga tgatgtgtac ggcgggcggc tgcctgtcca tgtacgcctg
     7981 attttggatg aatttgccaa cattggccaa atacccaatt tcgataaact cattgccacc
     8041 attcgaagcc gtgaaatatc ggcctctatt attttgcaga gccagtcgca gctaaaagcg
     8101 atttacaagg acgccgccga gatcatttcg gataactgcg atagtgtgct tttccttagt
     8161 gggcgcggca aaaatgccaa ggagatttcc gatgcgctgg ggaaagaaac gattgacagt
     8221 ttcaacacca gcgagaaccg gggaagccaa acgtcccacg gattgaacta tcaaaaatta
     8281 ggaaaggagt tgatgtccca agacgaaatt gccgtgatgg acggcggcaa gtgtatcttg
     8341 cagctacggg gtgtgcgccc gtttttatcg gagaaattcg atattaccaa gcatccccgg
     8401 tacaaatacc ttgccgacgc cgacaagaag aatacctttg acgtggacag atttttgact
     8461 atcacgcgcc ggaaacggca gcaagtggta acgcaggatg aagtattcga cctgtatgaa
     8521 atcgacctgt cggacgagga cgccgccgct gaataaacag cggctttttt cattccaaca
     8581 acaaaatcaa aaaatcatta tgagccggaa accggcagaa agaggtaaat ttatggcatt
     8641 ttttaattcc gcagttacta ctttgcagac tatcgtgatc ggactgggcg gcgctctgtg
     8701 cgtatggggc ggcatcaatc tgttggaggg atacgggcag gacaatccgg gggcaaaatc
     8761 gcagggtgtc aagcagcttg tcgctggcgg cggcgtggcc ctgatcggtg tcactctggt
     8821 tcccctgctg tccgggctgc tgggctgatc ctggcctttg tccctgtcca aacccttaac
     8881 taatcgcctc cgcgtcctcc cggccagacc gggagggcgc gggaaaggag gtgctacccg
     8941 tgattagtga aatcattgaa gaatggataa aaggcatcct catggacggt atcacgggca
     9001 acctgtccgg gctgttcgat acggtaaatg ccaaagtcgg agaaatcgcc gccgacgtgg
     9061 gacgaacccc gcaggcatgg aacagcggta ttttcaatat gctgcacagc ctgtcggaaa
     9121 ccgtgatcgt ccccatagcc ggggccatac tcgcccttgt catgtgctat gagcttatcc
     9181 agatgataac ggaaaagaac aatatgcacg actttgacag ctccatgttc ttccgctgga
     9241 tattcaaatc cgcgtttgca atcctgatcg taacgaacac atggaacatc gtcatgggcg
     9301 tattcgacgc cacccaaagc gtcgtcaatc aaagcgccgg tgtgattatc gggcagacat
     9361 ccattgattt taacaccctg ataccagacc ttgaaagcca attggaggct atgagcgtgg
     9421 gcgctctttt ggggctgtgg ttccaaaccc ttgttgtggg cctcaccatg aatatccttt
     9481 ccatctgcat tttccttgtg acctatggcc gcatggtgga aatctatgtt gtcacgtcgc
     9541 tggggcctat cccccttgcc acaatgggca acgcggaatg gcgcggcatg ggccaagggt
     9601 atctgaaatc cctgctggcg ctgggcttcc aagccttttt aatcatggtt gtggtgggta
     9661 tctacgcggt gctgatacag aatatcggtt ccgcttccga catatccggc gcaatctggg
     9721 gctgtatggg ctatacggtg ctgctgtgct tctgcctgtt caagaccggc agtatatcaa
     9781 aggccgtatt cggggcgcat tgatcccaaa atccaagcat acacaggagg aacttgctta
     9841 tttcaacgta caacatcatt tacgctgacc cgccgtggcg gtatgactgc aaaaacgtac
     9901 agggcgcagc ggaaaatcac tattccacca tgagcattga cgagctgtgc gccctgccgg
     9961 tggaacggct ggcgtccaaa gactgcctgc tgtttttgtg ggccacattc cccatgctgc
    10021 cggaagctct gcggttaatc aaagcgtggg gcttttcatt caagaccgtg gcttttgtat
    10081 ggctgaaaca gaaccgtaaa agccttacat ggttttacgg gctgggccgc tggacaaggg
    10141 gaaacgcgga aatctgcctg ctggcaacac acggcaagcc gaagcgtcgt tctgcctctg
    10201 tccatcagtt tattatcagc ccgattgaac aacacagcaa aaagccggat gtgacccgtg
    10261 aaaaaatcgt agagctggcg ggcgatttgc cccgcgtgga gctgtttgcc agacagaaaa
    10321 cccccggctg ggacgtgtgg gggaacgagg tggaatgtga ccttatcctg acgtgaaagg
    10381 aggtgccaaa tggcttatgt aaccgtcccc aaggacttaa cccatgtgaa aagcaaggtt
    10441 gtgtttgggc ttaccaaacg gcaactgatc tgtttttccg gggcgctggt gatcggcgtc
    10501 cccttatatt ttctcacccg tgactatctt accaacagcg cggcggccct gctcatggta
    10561 tttgccatgc tgccgggctt tttgcttgcc atgtacgagc gtcacggcca gccccttgaa
    10621 gtggtgatta tgcagatcat ccagtgctgc ttcatccagc caaaggagcg tccctatcag
    10681 accgacaaca cctacaccgc ccttgtgcgg caataccaga tggaacagga ggtaaaggcc
    10741 attgtccaaa aaggaaatcc caagagaaac cgaaaaaaca aagctgaccc gcgcccagcg
    10801 aaaagaaatt gacgcggtaa tccgtaaata taagggcgac ggcaggcccc acacggcgca
    10861 gcagagcatc ccctacgagg tcatgtaccc ggacggcgtg tgccgggtat cgcccggcgt
    10921 cttttccaag tgcattgagt ttgcggacat cagctatcag cttgcccagc cggacacgca
    10981 gacggctatc tttgaaaaac tgtgcgacct gtataactat gtggacgcct ccattcatat
    11041 ccagttttct ttcctcaatc ggaaagttga cccggtgcag tacgccaaga gctttgagat
    11101 cgcgccgcag ggggacgact tcgacgacat ccgggccgag tacaccggca ttctgcaaaa
    11161 gcagcttgca aacggcaaca acggcatggt aaagaccaaa tacctgacat tcaccatcga
    11221 ggccgaaagc gtgaaagcgg cgcgagccag attgaagcgc atcggctttg acctgttagg
    11281 ctatttcaag agcatggggg ccgtagccca tgtgatggac ggctgggaac ggctgaacct
    11341 gctgcatggc gtgtaccacc cggacggcga gatattcaat tttgactgga agtggctggc
    11401 cccgtccggc ctctccacca aggattttat tgccccgtcc tccctgtgct tcggcaatgc
    11461 aaagacattc ggcatgggcg gcaaatacgg cgcggtaagt ttcctgcaaa tcctgtcccc
    11521 ggagctgtcg gacgatatgc tggccgactt cctcaatacg gaaagcggtg ttttagtcaa
    11581 tctccatgtg caggccattg aacagaccaa ggcgatcaag accatcaagc gcaaaattac
    11641 cgaccttgac gctatgaaga ttgcggagca gaaaaaggcc gtccgcagcg gttacgatat
    11701 ggacattctt cccagcgacc ttgccaccta cggcgaggac gccaagaagc tgctgacaaa
    11761 gttgcagacc cgcaatgaac ggctgttcca gttgacgttc cttgtcctca acgtggccga
    11821 caccaagcaa aagctgaata acgacgtgtt ccaagccgca ggcgtggccc aaaagcataa
    11881 ctgtcccctt gtccggctgg actaccagca ggaacagggc cttgcaagca gcctgccgct
    11941 gggcgtcaat cagatcaaga tacagcgcag ccttacgact tccagcgtgg ccgtgttcgt
    12001 cccctttgtg acgcaggagc tttttcaggg cggcgcggcc atgtattacg gcatcaacgc
    12061 caagtcccgc aacatgatta tgctggacag gaagcaggcc cgttgcccca atgccttgaa
    12121 gctcggcacc cccggcagcg gcaaatccat gagctgtaaa tccgagatcg tcagtgtgtt
    12181 cttaacgacg cctgacgata tttttatttc agacccggag gccgaatatt acccccttgt
    12241 caaacggctc cacggacagg taatccggct gtcgcctacc agcaaggact ttgtgaaccc
    12301 gctggacatc aacctgaatt attcggagga cgataacccg ctggccctga aatccgactt
    12361 tgtgctgtcg ttctgtgagc ttgtcatggg cggcaagaac gggctggaag ccattgaaaa
    12421 gaccgtgata gaccgggctg tgcgcgtgat ctaccggccc tatctggcag acccccgccc
    12481 ggagaatatg ccgatcctgt ccgacctcca caaagcgttg ttagatcagc atgtcccgga
    12541 ggctgaccgg gtggcgcagg cccttgacct gtatgtgtcc ggctccctga acgtatttaa
    12601 ccaccgtacc aacgtggaca tcggcaaccg gcttgtgtcc tttgacatta aggagctggg
    12661 caagcagctc aaaaagctgg ggatgctcat tgtccaagac cagatatggg ggcgcgtcac
    12721 ggccaaccga agccaaggaa aggccacatg gtattttgcc gacgagttcc atttgctttt
    12781 gaaagaggaa cagacggcgg cctattctgc ggagatttgg aagcggttta ggaaatgggg
    12841 cggcattcca acaggtgcca cccagaacgt caaagacctg ctttcctccc cggaaattga
    12901 aaatatcctt gaaaacagcg acttcattac gctgctcaat caggcgtccg gggatagaaa
    12961 aatccttgcg gaacgcttga atttgtccac cgaacagcag aagtacatcg acaattccga
    13021 acccggcgag ggccttttga tctttgaaaa cgtggtgctg ccctttacca accccatccc
    13081 gcacaacacc cagctttaca agattatgac gacccgctta aacgaggtgg cgggagtatg
    13141 acccggcgac gccacaaagg aggtgaacca ccatgaaaga gctgaaagcc aaggcgaaag
    13201 tgacgcaggc catgacccgc gacgggctga cgctggaaaa tcaggccacc ggcgaggtgg
    13261 agaacatttc cagccgggag gccgaacagg atttgtccgc gccggggccg ggcggcaccg
    13321 ccgataagct gctggaacgg gccgacgcca tccatgacgg ccataaggcc aagaaagccg
    13381 cgaagcaggc cggggctgtg gccgccgagg gggacgctgc cctgcaccgg ccatccgccc
    13441 ggctccaact gtcggaggaa gaacgggccg acccggattt acagccctat atccgaaaat
    13501 cggacaaacg ggccgataag ctggataagg cccgcgccgc catccccaag aagcgcgtcc
    13561 cggtcaagga aaccgtcttt gacgaggcaa gcggcaaagc aaagaccgtc ctgcactttg
    13621 acaaacagga caaggggcct ccctccctga aacccaatcc ggcaggccgt cctgtttccg
    13681 aggtttttct attcggccac gggaaaatcc atgaagtcga gcatgaaaac gtgggtgtgg
    13741 agggcggcca taagggggag gaacttgccg agcggcaggc cggaaaagcc atccgcagca
    13801 ccatccggca ccacaggctg aaaccctact gggacgcgga aaaggccgag cgcaggctat
    13861 tgtctgccaa cgcggagtat ttctaccaga aatctttgcg ggataacccg gagatcgcac
    13921 aggcggccag caaccccatt tcccggttct ggcagaaaca gcagatcaag cgccagtacg
    13981 ccaaggccgc ccggacagcg ggccagaccg caggcgcggc ggcacagggc gcggccaaga
    14041 cagccggggc ctccacgaaa gcggccaagg ccgcagccaa agaaagtgaa cgggcggcct
    14101 cctttgtggc ccgccactgg aaaggggcgc tggccgtcct tgtgttgggg cttttgatgc
    14161 tgcttatcat cggcggctta cagtcctgca ccgccatgtt cggcagcgcc ggaagcggca
    14221 tcacggcgtc ctcttacttt tccgaggata gcgatatgtt ggccgccgag gacgcctacg
    14281 cggagctgga agccgagctg caagactatc tggacaacta cgaggccacc catgactatg
    14341 acgaatacca ttttgacctt gacgagatca gccatgaccc ctatgtgctg atttccatcc
    14401 tgtcggcgct ccatgacggg atatttacca tcggggaggt acagggtgat ttgtccatgc
    14461 tctttgacaa gcaatatatc ctgacagaaa acgtcgtggt agaaacccgt taccgcaccg
    14521 aaaccgatac atggacggac gcggagggca acacccatac agacacctac caagtgccgt
    14581 atgactatta catctgctac gtcacgctgg aaaacttcga cctgtcccat gtgccagtct
    14641 atatcatgga cgaggaaacg ctaagtttct attccctgta tatgtccacg ctaggagacc
    14701 ggcctgatct gttttccggc agccagtacc ccaacgcctc caccctgacg ccgccgacct
    14761 actacgacgt acccccggag gctttggagg atgccacctt tgccgccatg ctcaaagagg
    14821 cggaaaaata tatcggttat ccctatgtgt ggggcggcag ctctcccagc accagctttg
    14881 attgcagcgg cttcatttcg tgggtaatca atcatagtgg atggaacgtg ggacggctgg
    14941 gggcgcaggg cctatataac atctgcaccc ctgtttccag ttcgcaggcc aagcccggcg
    15001 accttgtatt tttcaaggga acctacgaca cccccggcgt gtcccacgtc ggcctgtatg
    15061 tgggcaacaa tgtgatgctg cattgcggga acccgatttc ctacacgaac cttacttcaa
    15121 actactggca atcccatttt tacagttacg ggcgtttacc ttaacgccag aaaggagctt
    15181 tcaattatgg caaccaaact tgaccgcatc gaaaaggaca tccagaaaac caagtctaag
    15241 atcgcggagt ttcagaaaca gcttcgggag ctggaaacgc agaaaaccga acaggagaat
    15301 ttgcagatca tccagcttgt gcgcggcatg aacatgaagc cggaggaatt tgccgcgttc
    15361 ttacgcagcg gcgcaatgca ggccgcccct gccgcaaccc cttaccatga acaggaggac
    15421 aatgcccatg aagaataaga ccagacggat ttcccgtatt ctccccgcac ttctggccgt
    15481 gatgctctgc gtcacggcct ttcccgttac cgcccttgca ggcggcaatg acccggcacc
    15541 ggccccgctg ccggaggcta caaccgaacc cgctacgggc ggtttggagc ctgaaacaga
    15601 cgaaaccggc accgccacgg acgggacaga aaccgaggcc gaaaaagata ccggccctct
    15661 gaccggcaag gacatcaccg acctgttttc cgcgctgttc ggttccaagg tgagcattgc
    15721 cgccacggac gacggcatcc agatcaccac cggcaccgac aaaaaagaac ctgaacagac
    15781 cggcaccgtc accaccaacg gcggcaggct gaatgtccgc accggcgcgg ggcttgacaa
    15841 gaccgcgttc acccagcttc ccaatgggac gacggttgag gtagtcggca cagacggcga
    15901 ctggattaaa attctcttgc cggagcgcat cggctatgtc cattccgact atatgaccgt
    15961 cagcgaaaag gaagtagcgg ctaccggcga gggcggtttt tccctctcca ttgacccgga
    16021 ggaaattgct tctctgctgg aactgttcaa tggcggcggg gccagcgccg ccctgtcccc
    16081 ggacgggaac ctgtcactga ttgacgacat cggcagcgcc gcgaaaaatg gcaagcagtt
    16141 tatcaccgtg gaaaccaaaa acggcaatgt gttttatctg attattgacc gggacgacga
    16201 gggaaaagaa actgtccatt tcttaaatca ggtggatgaa gccgatctgc tgacgctgat
    16261 ggaggacggg gaaaccgtca cccccgctgc tgtctgctcc tgtaccacga aatgcaaggc
    16321 cggggctgtg aacacgaatt gcccggtatg taaaaccaac ctgaccgagt gcagcggccc
    16381 ggagccgcag gaaccccagc cggaggaacc cgaagccccg gaggaagaac ccaagggcgg
    16441 cgcgggcggc ctgatcgtgt tcctgctggt ggcgctggcg ggcggcggtg cggcccttta
    16501 ctatttcaag ttcaaaaagc ccaaggctga aaccaccggc agcgacgatt tgggcgagta
    16561 tgattttggg gaggacgagg atttggagga cgaggaaccc gaaaccgagt ttgacccgga
    16621 agctgatttt gtgagtgaac aggaggacga ggaatgacat ataaacttgt aatcgcggaa
    16681 aaacccagcg tggcccgcag cattgcgggc gtgatcgggg ccacggagaa acacgacggc
    16741 tatttggagg ggaacggcta tctggtgagc tggtgcatcg gacatctggt gtcctttgcc
    16801 gacgccggac gctatgacga gcgtttcaaa aaatggcgct atgaggattt gcccattctc
    16861 ccggaaacat ggcagtacat cgtccccgac gacaagaaac agcagtttga cgttctctgt
    16921 tcgctgatgc agcgccccga cgtgaccggc cttgtgtgcg ccaccgacgc cgggcgcgag
    16981 ggggaattga ttttccgttt cgtctaccag atggcgggat gccaaaagcc ctttgagcgc
    17041 ctttggattt cctctatgga ggacagtgct attaaggacg gctttgccca cctgaaaccg
    17101 ggcggcgact atgatccgct gtatcaatcg gccctgtgcc gggccaaggc cgactggctg
    17161 atcggcatta acgccacccg gcttttttcc gtcctgtacc acaagaacct gactgtgggc
    17221 cgcgtccaga cgccgacctt aaaaatgctg gtggacaggg acgccaagat taccgatttc
    17281 aagaaagaga aatatcacat cgtccatatc acggcgggcg gcgcggacgc ggtaagcagc
    17341 cgcttttccg acgctgccga ggcaaacacc gtcaaggcgg cttgtgcaaa agcgcaggcc
    17401 gtttgcgttt ccgtgacgcg ggagaaaaag acggaacagc cgcccaagct ctatgacctt
    17461 accaccttgc agcgggaggc taaccggctt ttcggctata ccgccaagca gacccttgac
    17521 tatgcccagg cactgtatct aaagaagctg ctgacctatc cgagaacgga tagtcaatat
    17581 cttaccgacg atatgctgcc cgccgtggaa agccttgtgt ccggcctgtg ggagctggtg
    17641 ccgtttgcca agggcctgaa cctttccccg cagtttgacc gcatcctgaa cagcaaaaag
    17701 gtgtccgacc accacgccat tatccccacc gctgaatttg tgaagcaggg ctttggcact
    17761 ctggccgaga gtgaaaaaaa gctgctgtcc ctgatctgct gcaagctctt atgtgccgtg
    17821 gccgggccgc atatctatga ggccgtcacc gccacattta cctgtgccgg gcaggagttt
    17881 accgccaagg gcaagaccgt cctttccccc ggctggaaag agattgaacg ccggttccgt
    17941 tcttccttaa agaccgacgc cgacgaggac gccgaggcgg tgcgggagct gccggagctt
    18001 tgcgagggcc agacctttgc agacgtggcc gcctctgtca ccgagcattt caccacgccg
    18061 cccaagccct acaccgaaga tacgcttttg tccgctatgg aacgggccgg ggccgaggat
    18121 atgccggagg atgccgagcg caagggatta ggcacaccgg ccacccgcgc cgccattctg
    18181 gaaaagctgg tgcagatggg ctttgtccag agaaaaggca agcagctcat tcccaccaag
    18241 gacggcatca atctggctgt ggtgctgccg gaggcgctta cttctcccca gcttactgcc
    18301 gaatgggaaa accggctgac cgagatcgcc aaggggcagg ccgatcctga cgaatttatg
    18361 gacggcatcg agacgcaggc gcgggagctg gtgcagacct attcctgtat cagtgaggaa
    18421 aagcagaaat tgtttcaggc cgagcgtgtt cctatcggga cgtgtccccg ctgtggtgag
    18481 gctgtctatg agggcaagaa aaactactac tgcggaaacc gggcctgcca gttcgtcatg
    18541 tggaagaatg accgattttt tgaggaacgc aagaaagcgt tcaccccgaa gatcgccgct
    18601 gcgctgctca aaaccggcaa agtcaaggta aagggcctct attccgtaaa gaccggcaaa
    18661 acctacgacg ggacggtgct tttggctgat accgggggca agtacgtcaa ctaccgcatt
    18721 gaacacagga gctaaaggac agtaacacag caagcatagg gagtgtggct acactcccgg
    18781 taaaatcccc cggccgcgtc cctgccgggc cggggatttt tgcttgttgg ggaagtcccc
    18841 aaccccctat tttttgaaac agaacagaga aaggagtgac cgcgtgaacg aagtattttc
    18901 tatccaagtc cataaccggc agtttttgga acagggcaaa caaggcgtct ggctggattt
    18961 gcccaccaca accgaaacgc tgcaagccgc cctgcgggat gttggcatta ctgccgacaa
    19021 tccgcaggat ttttttatca acgggtattc ctgcccggag gacagacacc ttgccattcc
    19081 ctatgacatg gtgctggccg ccgacgtgga cgagctgaat ttccttgccg cccggctggg
    19141 ccagcttgac gccgccgaga tcgcagagct gaacgccgcc ctgcaaaatc cccgtggcgg
    19201 ctttgagaat atcggccaga tcatcgacta caccgaaaat gtggattact atgtgcatct
    19261 tcccgacgtt aggggggatg gacagttggg cgactactac ctgaaccgtt ccggcatggt
    19321 ggatatgccg gaggaatgga aagccgggat tgatacggcg cagtttggac gccacattgc
    19381 ccagcaggaa caaggcgttt ttacccagta cggctatctg gtgagaagcg gcgacgaatg
    19441 gcagcgcgtc catgagggcc agccggtgcc ggaggaatac cgggtgatgc actaccccca
    19501 gccggaagct gaccgggagg aaccgcaggc ccagcagccg gaggcatccg aaagccccga
    19561 caaagcgccg cccccggtta tcccgatcat gctggacggc atgaacagca aagaacgcat
    19621 gaaagtgatt actgaccgtc tggaaaccgg cgtacaggag ctttttgaaa gtagccgcta
    19681 tatggcttac ttatccgcta tgtccaagat gcacgattac agtctgaaca atacgctgct
    19741 gatcgccatg cagggcggtt cgattgtggc gggctataac aggtggcagg atgaatttga
    19801 ccgccatgtg aagcggggcg agaaaggcat taagatactg gccccggccc cgttcaaggt
    19861 taagcagcag atggagaaaa tcgacccggc cacccagcag cccgtgatcg gcgcggacgg
    19921 caagcccgtg accgaagaac aggaagtgac ggttccggcc tttaaggtgg tgacagtctt
    19981 tgacatcagc cagaccgagg gcaaggattt tcccatgccc tatatcagtg aacttaccgg
    20041 cgacgtgcag cagtatcagg atttctttgc cgcgctggaa cggacatcac cctatcccat
    20101 aagcattgag ccgatttcag acggggccaa gggccgctgc ttctacgcaa aacagcgcat
    20161 tgccatcaac gagggcatga gcgaattgca gaccctaaag accgccatcc atgagattgc
    20221 ccatgccaag ctccacgcca ttgaccggga ggcccccgcc gaggaacagg cggcccggcc
    20281 agaccgcagc acccgcgagg tacaggccga aagcgtggcc tataccgtct gccagtatta
    20341 cgggctggac acgtcggact attcttttgg ctatgtggcc gattggagca gcggcaggga
    20401 gttatccgag ctgaaagcct cccttgaaac catccgggcc acggccagcg aattgataac
    20461 cgagatcgac ggccattttg cccagcttca gcaggagcgc gaggcccggc aggaacagga
    20521 ggccgtcacg gttgacgtta ccccggaggc agcggccccg gcgcaggccg aggaagaaca
    20581 ggccccggcc cttgatccgg cagccgagcc gcttgtgact gtgctatgga gcgaaagccc
    20641 ccagctaaag gacggccagc aaatgccgtt gcatgaggcc gacgcgctgt ttgcccgtct
    20701 ggatgcagca tatccggcag aggcaggcta tgacaaaacc gcgttccgca ttgactgtat
    20761 ctttcagggc gagccggaca gctacgaggg gcggcaggat tttggagata gggacggttc
    20821 cctgatcgaa catatccaga gctaccacca attttacgcg caggacgaaa actggaaaaa
    20881 gcatgtaatc gctacaaccg gcatagaggg ctgggagcag gacaaggccc atcgggatat
    20941 gctgttaggc gagtttgtcc cctatatgaa gctgcattgc agccttgccc aaatggaaca
    21001 gacggcgcag ggccgcttac agtccgggga aaccctgacg ccggaggaaa cggcctattt
    21061 gggggcgctt ctctcttatg tgcaggagtg ccgccccatg ctcaatcagg gccagtatca
    21121 gttgccggag ccgccgaaac tggctgactt cgaccagagc ttgcaggact acaaagcaca
    21181 ggtacaggcc gagatcgcgc aggaggccgc cgcagccggt atgaccgtgg aggaatacgc
    21241 ggcggctggc tatgaagcac cccaacagga caccttttcc atctaccagc ttcgaggcgg
    21301 ggaggaaacc cgcgactatc ggtttgagcc atacgagcgt ttacaggccg cagggctggc
    21361 cgtggacagt gccaactatg accttgttta tacggcaccg ctggataaaa gcacgtcttt
    21421 ggaggatatt taccgcacat tcaacatcga ccacccggca gattttaggg gacacagcct
    21481 ttccgtttcc gacgtggtgg tgctgcacca gaatggacag gacaccgccc actatgtaga
    21541 cagcttcggc tatatggaag tgccggagtt tttgcgggaa aatcccctgc gtaccgccga
    21601 actgtctacg gagcagaacg aaaacatgat tgacggcatt atcaacaata cgccgcccga
    21661 accgcagccg gaggaacccg aacagctatc ttttgaggat gtggcagttg cttccggcca
    21721 gacacaggag gaacccccgg aggctgcgcc cccgcaaacg gctgtccgct attatcccat
    21781 caatgaggga gccgcccgcc gcgccaagga agccatgagc ttttctgact accggcccgg
    21841 cagcgccacg gcggaatacc ggcactatgt cgatcaggcc gtggaaattg cggagcgcca
    21901 gaaaaagcgt gtggagccag agtatcacga aaagatagac agcctccttg acacctacgc
    21961 ccgcaagctg gccgagaaca tgaataaggg ctatgagatt accgcccgcg tcccctctgt
    22021 cctgattgcc gggccgtcca atttcccggt acgggcgaaa gaaaagcaga acgccgccag
    22081 tgaccgcaac atggaggaat ttcagtacat tcagggcttg cttgacaaaa tccgcagcac
    22141 cggcatgggt ggtatcagcg ccgacgatcc gcaggccgtt tccaagctgg aaaagaaact
    22201 ggaaaagctg gaagcgtcgc aggagttgat gaaggccgtc aatgcctact accgcaagca
    22261 tgggacgctg gacggatgcc cccatctgac cgaaagaggc attgaaaacc tgaaagcgga
    22321 tatggcgtcg ggctggcact atgagaaaaa accgttccag tcctggcagc tctccaacaa
    22381 taacgccgag atacgccggt taaagggccg cattgaggaa ttgacccgcc aaaaggaggc
    22441 ggcctatgtg ggatgggagt ttgacggcgg cactgtggag atcaaccggg tggccaaccg
    22501 cctgcaaatc ttctttgagg ggaagccgga tgctgctgta cgcgacgagc tgaaaagcaa
    22561 cggtttccgc tggtcgccca aggccggggc atggcagcgg cagttaaacg acaccacaat
    22621 ccgcgtcgct gaccgtatca agtgcatcca gcccctttcc ggcgaaaagc ccagcgcctt
    22681 acagcttgcg gcccgcaggg agaaagaaaa gccctctatc cgggcgcagc tcaacgcggc
    22741 caagaccgaa caggccaagc agccaccggc gcgggaaaaa tcaaagggat tggaggtaga
    22801 gtaaatgcag aagtttgaaa atgtggacgt tctggccgcg ctggaacaga tcatgcggca
    22861 gaacaccgcg ttttatcaaa gtgactttgg cattgacaaa gacattatca ggcgggatgc
    22921 cgccagcgat caggccgcag acaagaccct gctctggatg tcccggccct ccgggacgta
    22981 ctgtttccgg gaacgtgatg ttttcctgaa agacacccga cagtacaaca catggaaatt
    23041 ttacggggag cagacccgtg acaagatact ggcctacgcg gtggagctga ccggcacaca
    23101 gggcggcact atccggggca atctctatga gctggactat ccgcagcatt tccggcacgt
    23161 cattgaaacc gcccagccgg tgagtgtgaa ccggctcttt tatgagcatg gcacccgtga
    23221 catcccggag agccagcgtt ttgacggaag ccctgaccgg gtattgggaa actttttgta
    23281 ctatgaggcc cagccccatg acccggctgt gctgcaggag gcgctacgga cggagcagca
    23341 cagccggggg cgggccgtcc ccggcgattt caaagtccac gtcaccgctt tgcatgacag
    23401 ccggattgaa accgaggccc ggcgtattgt ggacagcctg aaagatctgt ccgcgcctaa
    23461 cagccccaat aaaacgcatt tcatggtgga gatctccccg cactttgcgg cgattgcttc
    23521 caccaaggat aatgaccggc tctttgccat gctgccctat aaatccctgt gttttaccgg
    23581 gatgaaaggc aggcatggcg tgtatgccgt gattaaccgg gacgagcgcc gggatgtgag
    23641 tattcgcagg ccccggccct ctatccgcaa gcagctatcc gacagcaaac aggccgccag
    23701 cccaaaaaag gcggcggcca gaaccaaaaa gaatgaattg gaggtataag gaatgatgca
    23761 ctttaccgtg gaggaagaaa acctgatctg tatgtaccac aatgcagacc ggcgcagaac
    23821 gataaacagg ctcaccgccg tcatgctggt tatggatggg gatatgcggg cgcaggccca
    23881 gcagaccctt tccaagctgg aacgcatgac ggatgccgac tatgacggcc agaagttcca
    23941 cttcacagac gaataacgaa cagcagacgc cgggcgcggc ggccatgtgg tcgcttgcgt
    24001 ccggcgtctt ttctttttgc ctattcctac gcatttagaa cccggtattg tcggggatag
    24061 gatgaagtat tcgcttgccc ctgcaaacat gcgggagaag ccttgcagcg ggcggttttc
    24121 aatcccttaa atgcgtaggt tgcagctata attagacccc tgaaacagat atagccgcgc
    24181 agcgggtgta tctgtttcag gggtgtgcag gtgatagccg caaagcggcg taagagggtg
    24241 cagccctctt gccgtctatc tctgttccag cgggaagctc ggcaatgctt ccagcagttt
    24301 cagggaaatg cgctgccgta tatcttcgtc aatgactttc ttctttttgc cgtttgcctg
    24361 tctgatctcc accgtggaaa gctcgttgat gtagtcagca taatgggcca acactttttc
    24421 cgtggcccac ctctcaccgg caacggcggc tttgatcgtt tcatagtcca gcagcttttc
    24481 ttgtccgtcc atcctgatac ccccgtcaga ctgatttttt ctatgatacc atattcggaa
    24541 gcatggaacc agagaaaacg gcgcttttct gctggtaaat tctacgcatt tagaacagca
    24601 cttcggcggg gataggataa aacacccaca taccccgctg accatgccgg aaaagccttg
    24661 aaatataagg gcttttacag ctctaagtgc gtaggtttcc agtatctttt ccgctggcgc
    24721 tcggcctctt tgcggcggcg catccgtttg gagcaggccg cgcagtattt ggcccggtta
    24781 gacttcggcg tgaacgtggc cccgcactca cagcagcgtt tcacttcgtc ccggtctttg
    24841 gtgatctcgg catacagggc cgcatccagc gggaggacag cggccttaaa ccagcggcac
    24901 agaagcgaat aggaaatgct ctgtacgcaa atacattctt cgccgtcgtc cagcaacagg
    24961 cagttgccgt cacaatagtt gcagcactca tgcgtcagct tccgggcctt gcgatattga
    25021 gggtaattca ttcgtggaat actcatagct cttgcgtcca ttcctttccc ggcgtcatac
    25081 gcaaaatgcc gtccacattc tgcttgatga tgccgtattc ctgcatctgc tttttcgctt
    25141 cgccgtactt ctcatacagc cgttcctttt cctcggccaa tcgcttgtac tcggctttca
    25201 gggcgtacag atcggggagc tttttcacac cctgtccctt tagggccttt gccgcagctt
    25261 catacaaaat caacgtgctt tcatgctcac gccggaattt tgccttatcc gctgcattgc
    25321 ggtattccat agccacgggc cagagctgct tgtaggtaga aatattcttt atcagcaccg
    25381 ccatatccgc aagccggtgt tccatagctt tgagggtagc ggcggcctcg tcgctggcgg
    25441 cggtgatctc ggccactttg ctttccaaat ccgggtaggt gtctatccca tgttcagtca
    25501 ggaaattcaa agtctttgcg gcctgcttca aattgtggag cttcgcccac ctctcatagc
    25561 ctgccgactg ctgggcctta atgttgtttt ccagatcaat ccgcaaagaa atccccttgc
    25621 gctctttggg cgctctggtg ataacgcggc ctttgatacg ctctttgatg gcttcctcgg
    25681 tgtaggcttc ccccaatgtc ttgcagcggg taaagcgttc ctgtccggga gcgcggaaag
    25741 aaataaactt tcccggcttg atctcatagc cttgcgcctg catgagccgc aggaaatcat
    25801 caaaatcttt tgcctgcggg atagcggcgt caatggctgc tttgagcttc gctttccagc
    25861 tcgtcccttt ccgctgggcg tcccactcgg catagctctt gcccttactc tggccgggct
    25921 tcaccacgga caatccgttt tccttgcaca gcctgtcgct ggtgcgccgg atataggcat
    25981 agctctgttt gttggaaatg tacttgcgct gatttaccat atccacggca cagaaaataa
    26041 tgtgattgtg gacgtggccc ttatcaatat gggtagtcag cacataggga tatttccctt
    26101 gcagcacttc ctcggcaagc tgcttcccga tctcatgggc ctgttccggc gtggcttcgc
    26161 cgggggcaaa ggattgtatc aggtggtggc ccagattatt gcccttttgg tatgcctgcg
    26221 ccagcagcat ttcaaattca atgtccgctg tttcataaga gcaggcaaag gaggccacca
    26281 gcagcttgcc gtcagttttg tccgggttct cgatgtagtc aagggctttt ttcagcgttg
    26341 acttgatagg atgtatcttt gtaactgcca tatctgcgcc agcgccccct ttatatcctc
    26401 gatgtcctgt gcgtacaccg gccccatacc gttcagcctc tttgcaatct gattgacgtt
    26461 gacgccgatc ttctgtatct cggcggtctg cgcccggatg tcgctggtgt ccatgttgac
    26521 gatatagccg tcaatgagca tcttccgggc gtaggctgaa aagttcttcg tatgcagcag
    26581 cgccattttc tgttcaatca tagcccgttc ctccggcgtc acagggacgc gcagcacgat
    26641 ttttcgcttt ctgtttgcca tgcttcaccg tcctttccat tcaggggttt ggggatttcc
    26701 ccaacaagca aaacggacgc ggcccggcag ggacggggca ggccgttttt ccgggagtgg
    26761 ctacactccc tatgcttgct acgttactgt ttctccacta acaagacgtt tccaaagccc
    26821 caaactaccc gcaaaatagc cctctggaaa gaaaaaagtg caaaaaaata gaagctacgc
    26881 tgtgcagctc ccgctaaaag taaaacagag gatgccagtt acacatcctc cgtttcattc
    26941 ttcttcggct tttcaattag tatggcgctg tcaatcgcgc cctcgatgat cggcaggtat
    27001 tcttcggggc agagtttcag cttgtggctg accctttgcc gcagttcgct ttcctcccgc
    27061 atgatctccg ggttaaagta gcgttccaca ggaagcccgc aggctttaat aagctgtatg
    27121 acaaccggca gactgggaat ggccccgtcg ttttcgatgt tggcaagata gcgccagtca
    27181 atatttattt tctctgccat tgctttgcgc gaaacgcgct ttgcttgccg ggccgctttc
    27241 acatccgcgc cgaaagtttc aaagccggga caatcttcaa tattcgccat atcgcacctc
    27301 ccacttacat tgtatatttc atactctgcc cgtggaatgt tggtatatgc acctttctta
    27361 aagtttatat ttcacatttt gtttctttta ttcttcgagc aaaagaatta taatgtaccc
    27421 tgtggaggtg tactatggac tacatgacgt tgaaagaggc aggcgagaaa tggggtgtgc
    27481 ccccacgatg gataaactac tattgtgctg cgggacgcat ccccggcgct gtaaagatgg
    27541 cgacgatctg gctcattccc aaaactgcgg aaaagccgat tgacaggcgt acaaagaaag
    27601 gaaaggcggt tactgaatag tataatgaaa ccggcgcatt ttggatatgg ttttgaagag
    27661 agagaaagca tggtattttg tcacggaaaa actataagat gatagatggc aggctgctcc
    27721 agaccgataa aaagtattct catctgaaac agaaagaaaa gatttacaca tggatgtatg
    27781 aagaagcgaa actttatcat gacagaaatg gaaaatgccc gaaacaaaga cgaggaagct
    27841 gctgctgtat cagccgtata tggtagaatt gaaaaggccg gcatctggat tctttatggt
    27901 gaagtctcca gacattggat aactgctggt ctaatgcgcc tttgagtatg gggtgattga
    27961 ttttaatacc ggggaggtac ggctttttga ggaaaatatt ctgggattta catttggcga
    28021 ttattacatt tcctgtaact gcaaggacac ggatgatgaa gatatgagga atatagactt
    28081 gctgattttc tactgtcttg aacggtatta ggactgaatc tgctgcgcgg agtgcggcaa
    28141 gagcgaccgg agggagtaca cacaggccct gcctgtgtga aaagccatac cgcaaggtgc
    28201 attcgcaaaa aagaggccgc gcattttgct gaggcttggg gtgtccccaa caagcaaaac
    28261 gagaacgccg caggcgggca agtggtggat cagaatatcc gtaaaggata ttctgatcca
    28321 ttgcttgcca gtattatcgg gatgttttga caaccgctgt aatcgaaaca tcccaaacat
    28381 taagaaggtg ttaattatta ttatcttgat ttaattcgtt taaaccaata atatagatac
    28441 atacaccatg aaaagaagcg agtatcccaa tgacggatga ttaaaatccg aaaagaaatc
    28501 gctttgaaac tacagggaaa ctacagactg ttatgttatc ttcttaaaat ggagggattt
    28561 ttatgtcgat acgaattcta cttgtcgagg atgatgatca tatctgtaat acagtaaggg
    28621 cgtttctggc tgaggcagga tatcaggtgg atgcctgcac agatggaaat gaggcataca
    28681 ccaagtttta cgaaaacact tatcaactgg ttattcttga tattatgctg cccggtatga
    28741 acgggcatga acttttgcgt gaatttcgtg cgaaaaatga tactcccatt ctgatgatga
    28801 cagccctgtc ggatgacgaa aaccaaatcc gggcgtttga tgcagaggca gacgactatg
    28861 taacaaagcc attcaagatg cagattttac taaagcgggt ggaagccctg ctgcggcgca
    28921 gcggtgcgct ggcaaaggaa atccgtgtcg gcaggctgac acttctgccg gaggatttca
    28981 cggtactttg tgacggtaca gagctgcccc tgacacgaaa agaatttgaa atccttttgc
    29041 tgctggtgca gaacaaaggc agaaccttaa cgcatgaaat cattttgtca cgtatatggg
    29101 gatatgactt tgagggtgat ggcagcacag tccacactca tatcaaaaat ttgcgggcca
    29161 agctgccgga aaatatcatc aaaaccattc gcggtgtagg ataccgattg gaggaatcat
    29221 aataatggaa agaaaaggga ttttcattaa ggttttttcc tatacgatca ttgccctgct
    29281 actgcttgtc ggtgtaacag caacactgtt tgcacagcaa tttgtgtctt atttcagagt
    29341 gatggaatta cagcaaacag taaaatccta tcagccattg gtggaactga ttcagaatag
    29401 cgataggctt gatattcaag aggtggcagg gctgtttcac tacaataacc aatcctttga
    29461 gttttatatt gaagataaag agggaagcgt actctatgcc acaccaaatg ccaatacatc
    29521 aaatagtttt agacccgact ttctttatgt ggtacataga gatgataata tttcgattgt
    29581 tgctcaaagc aaggcaggtg tgggattgct ttatcaaggg ctgacaattc ggggaattgt
    29641 tatgattgcg ataatggttg tattcagcct tttatgcgcg tatatctttg cgcggcaaat
    29701 gacaacgccg atcaaagcct tagcggacag tgcgaataaa atggcaaacc tgaaagatgt
    29761 accgccgccg ctggagcgaa aggatgagct tggcgcactg gctcatgata tgcattccat
    29821 gtatgtcagg ctgaaagaaa ccatcgcaag gctggaggat gaaatcgcaa gggaacatga
    29881 gttggaggaa acacagcgat atttctttgc ggcagcttct catgagctaa aaacgcccat
    29941 cgcggctaca agcgttctgt tggagggaat gcttgaaaat atcggtgact acaaagatca
    30001 ttctaagtat ctgcgcgaat gcatcaaaat gatggatagg cagggcaaaa tcatttccga
    30061 aatactggag cttgtcagcc tgaatgatgg gagaatcgta cccatagctg aaccgttgga
    30121 catagggcgc acggttgccg agttgctgcc cgattttcaa accttggcag aggcaaacaa
    30181 ccagcggttc gtcacagata ttccagccgg gcaaattgtc ctgtccgatc cgaggctgct
    30241 ccaaaaggca ctatccaatg tcatattgaa tgcagttcag aacacgccgc agggaggcga
    30301 ggtacggata tggagtgagc ctggtgctga aaaatgccgc ctttttgttt tgaacatggg
    30361 cgttcacatt gatgatactg cgcttccaag gctgttcacc ccattctatc gcattgatca
    30421 ggcgcaaagc agaaaaagtg ggcgaagcgg tttaggactt gccatcgtac aaaaaacgct
    30481 ggatgccatg agcctccagt atgcgctgga aaacacctcg gatggcgttt tgttctggct
    30541 ggatttaccg ctcacatcaa cattgtaaat atttaaaact taaatgattt tgaccgacag
    30601 gtataaccct gccggtcttt ttttgctgct acaggaaaac tacagactgg ctacagggaa
    30661 agtacagatg cgcttgccat aataacaatc gtaccagcca caaatcgtag ttttattgca
    30721 aaggaggcat tcgatcaaat ggaaaaaagc aactatcatt ccaatgcgga tcatcacaaa
    30781 cggcatatga aacaatccgt ggaaaagcgg gcttttctat gtgcgttcat tatttcgttc
    30841 acagtctgca cgctgttttt ggggcggaga ctggcttccg tattggaggc aacacagata
    30901 ccgcccatcc ctgcaactca tacaggcagc agcactgacg tagtggagaa tttggaggaa
    30961 aacgctcttg ccaccgccaa agaacaggga gatgaacagg aatggagcct gattttagtg
    31021 aacaggcaga accccatccc cgcacagtac gatgtggagc ttgagcaact atcaaatggt
    31081 gagcggatag atattcggat ttctccctat cttcaagatt tgtttgatgc cgcaagaact
    31141 gatggagttt acccgattgt cgcatccgga taccgaacaa cagaaaaaca gcaagaaatt
    31201 atggatgaaa aaattgccga atataaggcg aaaggctaca cctctgcaca ggctaaagcg
    31261 gaagcagaaa cttgggtggc cgtgccggga acgagcgagc atcagcttgg tcttgctgtg
    31321 gatatcaatg cggacggaat tcattcaaca ggcaacgagg tttatagatg gctggatgaa
    31381 aacagctatc gttttggttt tattcgtcgc tacccaccag acaagacaga gataaccggt
    31441 gtgagcaacg agccgtggca ttaccgatat gttggcatcg aagctgccac agagatgtac
    31501 aaccaagggg tttgccttga ggaatattta aaaccagaaa aatgagaaaa ggatgttatg
    31561 ttatggacag aaaaagattg acacagcgtt tcccgttcct gcttccaatg agacgggcgc
    31621 agagaaaaat gtgcttttat gcgggaatga gatttgacgg ctgtcgctat gcgcagacga
    31681 taggggaaaa atcgctttcc catttgctct ttgaaacgga ttgcgcatta tacaaccaca
    31741 ataccggatt tgacatgata taccaggaaa acaaggtgtt caacttaaag ctggcagcaa
    31801 agaccttaaa cggcttattg ataagaccgg gggaaccctt ttctttctgg tggctggtac
    31861 gccatgcgga caaagatacc ccctataaag acggccttac ggtgaccaat ggtaaactca
    31921 ccaccatgtc gggcggcggt atgtgccaga tgagcaattt actattttgg atgttcctgc
    31981 atacgccatt gacaattatc cagcgcagag gtcacgaagt aaaggagttt ccagagccaa
    32041 acagtgacga gattaaaggg gtggatgcaa ccatttcaga gggctggatt gatttaaaag
    32101 tgcgaaacga taccgactgc acctaccaaa tatgggtgac cttagatgat gagaaaatca
    32161 tcggtcaggt gtccgccgac aaagagcccc aagcattata caaaattaca aatggcagta
    32221 tccagtatgt ccgtgaaagt ggcgggattt atgaatatgc ccaggttaaa cggatgcaag
    32281 ttgccttagg taccggggaa ataatagatt gcaagctgct ttatacaaac aaatgcaaaa
    32341 tctgttatcc cctcccggaa agtgtggata ttcaggagga gaaccaatga gaaaaagtgt
    32401 gggcattact gtttttggat gcgaacagga tgaggcaaat gctttccgcg ctttatcgcc
    32461 ggattttcat attatcccta cgctgattag cgatgcgata tcggcagaca acgcaaaatt
    32521 ggccgctggc aatcaatgcg ttagcgtagg ccataagtcc gaggtttccg aggcgacaat
    32581 tcttgcgctg agaaaggtcg gggtaaaata catttctacc cgcagcatcg gctgcgatca
    32641 cattgatacg actgccgccg agagaatggg aatctcggtt ggcacggttg cgtattcgcc
    32701 ggacagcgtt gcggattatg ctttgatgct gatgctgatg gccatacggg gtgcaaaacc
    32761 caccatgcac gccgtggcgc aacaagattt cagattggat cgtatccggg ggaaagaact
    32821 gggggatatg actgtgggag ttattggaac cggccatatc gggcaagcgg tcgtcaaaag
    32881 gctgcgggga tttggatgcc atgtgctggc ctatgataac agccgaaaaa tggatgcaga
    32941 ttatgtccag cttgatgagc ttctaaaaaa cagcgatatt gttacgctcc atgtgccgct
    33001 ttgtgcggat acccgccatc tgatcggtca gaagcaaatt ggagagatga agcaaggcgc
    33061 atttttaatc aacaccgggc gcggagcgct tgtcgatacc ggggcgctgg tggaggcgtt
    33121 ggaaagcgga aagctgggtg gtgcggcact ggatgtgttg gagggcgagg atcagtttgt
    33181 ttataccgat tgctcgcaga aagtgcttga ccatcccttt ttgtcgcagc ttttaaggat
    33241 gccgaatgtg atcatcacac cccatacggc gtactacact gagcgtgtgc tgcaggatac
    33301 tacagaaaaa acaatcagga attgtctcaa ttttgaaagg agtttacagc atgaatagaa
    33361 taaaagtcgc aatcatcttc ggcggttgct cggaggaaca tgatgtgtcg gtaaaatccg
    33421 caatagaaat tgctgcgaac attgatacgg aaaaattcga tccgcactac atcggaatta
    33481 caaaaaacgg tgtatggaag ctatgcaaga agccatgtac ggaatgggaa gccgacagtc
    33541 tccccgccat actctccccg gataggaaaa cgcatgggct gcttgtcatg aaagaaagcg
    33601 aatacgaaac acggcgtatt gatgtggctt tcccggtttt gcatggcaaa tgcggggagg
    33661 atggtgcgat acaggggctg tttgtattgt ctggtatccc ctatgtgggc tgtgatattc
    33721 aaagctccgc agcttgcatg gacaaatcac tggcctacat tcttacaaaa aatgcgggca
    33781 tcgccgttcc cgaatttcaa atgattgata aaggtgacaa gccggaggcg ggtgcgctta
    33841 cctaccctgt ctttgtgaag ccggcacggt caggttcgtc ctttggcgta accaaagtaa
    33901 acggtacgga agaacttaac gctgcgatag aagcggcagg acaatatgat ggaaaaatct
    33961 taattgagca agcgatttcg ggctgtgagg tcgggtgtgc ggtcatgggg aacgaggatg
    34021 atttgattgt cggcgaagtg gatcaaatcc ggctgagcca cggtaccttc cgcatccatc
    34081 aggaaaacga gccggaaaaa ggctcagaaa atgcgatgat tacagttccc gcagacattc
    34141 cggtcgagga acgaaatcgg gtgcaggaaa cggcaaagaa agtatatcgg gtgcttggat
    34201 gcagagggct tgcccgtgtt gatctttttt tgcaggagga tggcggcatc gttctaaatg
    34261 aggtcaatac cctgcccggt tttacatcgt acagccgcta cccacgtatg atggccgccg
    34321 caggaatcac gcttcctgca ctgattgaca gcctgattac attggcgtta aagaggtgat
    34381 aagtatggaa aatggttttt tgtttttaga tgaaatgttg catggcgtcc gttgggatgc
    34441 caagtacgcc acatgggata acttcacagg aaaaccggtg gatgggtatg aggtgaatcg
    34501 catcatcggc acaaaggccg tggcgtttgc tctgcgcgag gcacaaatcc atgcggctgc
    34561 gcttggctat ggcttgcttt tatgggatgg atatcggcca agaactgcgg tggactgctt
    34621 cctgcgttgg gcagcgcaac cggaggacaa tctcacaaaa gaaaaatttt accccaatat
    34681 agagcgagcc gagttgatta caaagggtta tgtggcctca caatccagcc atagccgtgg
    34741 aagcgcaatt gatcttacgc tctaccacct ggatacaggg gaacttgttt caatgggaag
    34801 taacttcgat tttatggacg aacggtcgca tcatacagca aaagggatag gggatgcaga
    34861 ggcacaaaat cgaagatgct tgcgtaaaat catggaaagc agcggatttc agtcttatcg
    34921 ctttgaatgg tggcactata agttgattga tgagccatac cccgatacct attttaattt
    34981 tgccgtttca taatgaaagt attggttttg tatcagattt tggatttgat aaaatctatg
    35041 ctggtcatgg acaatctttt actggaaagt ggttaaagca tcttttgtaa tacattgcaa
    35101 attatagtat tcaatctgcc cagcggcaga aaagaaaaaa accgctgttg ggcagacctt
    35161 tcccacgccc attttgtatt ttgctggcgg cggttttgag aaatcaaggc cgccgttctt
    35221 ttctggcagc aaaaggtgtg gcggcccata ggaggatgcc gctatgctgt tttgctattg
    35281 ccatgctcta atccacttcc accactcaaa aaaagccttg cccctccaca gggctattcc
    35341 ggttatgagt atgtactata ccatgtaaat cagcagcata gcaaagcatt ttctcgcccg
    35401 gtaggtttgc gacctgccgg gcgatttttg tcgtcttttg cggcccggct gtccccaaaa
    35461 aaattttttg agaaattttc aaaaaggagg tatttagcgg gtagctggcg gccttgtcaa
    35521 agtcttgtta gcggaaaggg agagaaccac ctaagtcccc cacagaaagg gggtgagaag
    35581 atggatgcta tcccccgcga ctatgaagcg cggtgcatgt tcgatgcttt ttgcaagacg
    35641 gtactgcgta acgaggccaa aagctacttg gctgaaatga agcgccgccg tgaccgtgaa
    35701 gtgtcactaa gctctttgtc acaggcagat ttggacaagc tctgtacagt agatcactac
    35761 cccagcgaca gctttacgtt ttcgtcgcat ggctatgacc tacatatcaa caatgagctt
    35821 gttgccgaag cctttgccgc gctgcccagc atggagcaga gtattttaat cctgcactgt
    35881 gttctggata tggcagatgg tgagatcggc ggccttgtgg gaatgtcccg gagtgccgtt
    35941 cagcggcaca ggacaaatac cttatcggag ctgcggaaac agctaaaggc gttgatgccg
    36001 aagggaggtt agacgcggat gaagaacccg aactacaagg gcattgagct tttgcccctt
    36061 tcggtgatcg aggccgcccg cgctggggat gccggagccg tagagcgcgt tttgcagtat
    36121 tacagcggtt acatgaacaa gctgtgtacc cggacgctct atgacgaaaa cggctatccg
    36181 catgtgtgtc tggacgaggc catgaagcgc cgtctggaaa tcaagctcat ccacgctatc
    36241 gtcacgaact gacgaaccgg ccccggcagc atgaaacggc ttaccctttc cccgtttcgg
    36301 tgttttcccg gtggcctgat cgcaccttga taaatatgcc cgcaagataa cggcggcgca
    36361 tcatagggca tacggacaca ttctgtctgt gccgagccgg acggctggtg cgccatgata
    36421 cttttcccta cgggaaaagc ggagcgagga acaccacgcc gcaatgtgag cgtggcggct
    36481 tgcgggcgac gacgtacagg caggactatg atactccctt atagccacag tccgagcgtt
    36541 aaaagcgtcg caggcaatgg gtagggccgc gtgagaacca cgcgggggtg aaagtcccgt
    36601 ggagctgtgc cagcagccgt ccgtctatgc ccctaaatca cacaaacctt tgaatttgtg
    36661 aaagggggct gcattatgaa ccatgatgtg cctatttggg aaaaatacac gctgacgatt
    36721 gaggaagcgt ctaaatattt ccgtatcgga gaaaacaaat tgcgtaagct ggccgaggaa
    36781 aatccggcct ctggctgggt cattatgaat ggcaaccgca tccagatcaa acgcaagcag
    36841 tttgagaaaa taattgacac tttggacaca atctaatagt gaaaaagggc cgcagatatg
    36901 ttataataat ttataagcat atatgcggct ctttccgtca tggaaaggag catgacgaga
    36961 tgtcagaaaa aagacgagac agcaaaaatc gcgttttgcg gtctggagag agccagagaa
    37021 aagacggacg atatgcttac aaatatgttg atacctttgg aaaaccgcag tttgtttact
    37081 catggaagtt agtgcctacg gataagaccc cggcaggtaa acgggaggat atttcactcc
    37141 gggaaaagga gaaagaaatc cagaaagacc ttgacgacgg gatagacacc atcggcaaga
    37201 aaatgaccgt ctgccagctc tacgccaagc agatcaggca ccggggcaat gtgaagcaca
    37261 acaccaaact gggccgggaa cggctgatgc gtattctgga acaagatcgg ctggggagct
    37321 gcccgattga cagtgtgaag ctgtccgacg caaaggaatg ggcgcttcgg atgaaagaaa
    37381 agggcctttc ttataagacc atcaataacg acaagcgttc cctgaaagcg gctttttaca
    37441 ccgccataca ggacgattgc atccgaaaaa acccgtttga cttccagctt agtgacgttc
    37501 tggacgacga tacggaacca aaggtgcctc ttacaccagc acaggaagaa agttttctgt
    37561 cctttattca aggtgataag gtttaccaaa agcattatga cgcaatcgtt attctgctgg
    37621 ggacagggct tcgcatttcg gaactgtgcg gactgacgga caaagatttg gattttgaaa
    37681 accgggtaat catcgtgagc caccagcttt tgagaaatac cggcgtcggt tactatattg
    37741 acgaacccaa gacccaaagc ggcgtcagaa aaatccccat gaatgaggaa gtgtatcagg
    37801 cgttccagcg agtgataaaa aaccgcaaag gtgcaaagcc gttcattatt gacgggtatg
    37861 ccaatttcct gtttctcaaa cagaacggct atcccatgac ggcggtagat tatggcggga
    37921 tgtttggcag gcttgtgaag aagtacaaca agagccatga agaagcgttg ccgaaaacga
    37981 cgacgcccca tgctatgcgt catacattct gcacccggtt agccaatgcg ggaatgaacc
    38041 ccaaagcctt gcagtacatt atgggacatt ccaatatcac catgacgctg aactattatg
    38101 cacacgccac attcgattcc gcaagggcag aaatggaacg gctggcagcc tgacacaagg
    38161 ccggttttac tactccattt actacttttg agggggaaat ggtgagaggt aataagaaca
    38221 tttgtaagta tctaacaata tcaaaaatgc cggaaaagcc cggaaacacg ggctataccg
    38281 acattcaaga acttctaaaa agataatcta aaatcccata taattttgga ataaaagtgg
    38341 ctcgttttgg tgacaacatg agaaacgtgg gtgtcacaga aggagacaaa gtggaagcac
    38401 agattcaatt tggttggact gttgattatt ttggtatcgg agatcttgta caagtaatcg
    38461 atcgcgtatc agacgaagaa gtcgatcaat tatttgaaga gtacaaggaa ttgtatacct
    38521 tcgactatgg tgattatgaa gaaaagacat gggaggaaca tgtaaaagta caagctcagc
    38581 aggaaatcgg tattcgccgt ttcttagaag aaggaggcta taacgctttt acgactaatt
    38641 ttgaagacct gtatggaatg aaacaactac ctggactagc tgtacaacgt ttgatggcag
    38701 aaggatacgg ttttgctggg gaaggcgact ggaaaactgc agcgattgat cggttgctga
    38761 aaatcatggc tcgagggaaa gatacaggat tcatggaaga ttatacttac gagctagcta
    38821 gtggccaaga agcaatcttg gaatcccata tgatggaagt agatccgacg cttgctgcga
    38881 cgaaaccaag aatcgttgtt tctcctttat caatgggaga tagagaagat ccggcgcgtc
    38941 ttgtatttga tgggaaagca ggagaagggg tagtcgtatc gatggcagat ttcggtacgc
    39001 attataaact gctgatcaat gaagtagaag cctttgaacc aacgactgaa gcacctaatt
    39061 tacctgttgc acgtgtgtta tggaaaacta aaccgaattt ccatgaaggt gtccattcat
    39121 ggattcaggc aggtggcggt catcataccg ttgtctcgct aaatctaaca acagatcaaa
    39181 ttgaaacgtg ggcaaaatta gttgagttgg aaacagtggt tattagataa aaagaggttg
    39241 tgaaaaagcc acttagtttt aagaaataag aagagattga cgaaatttgc ttttcaactt
    39301 ttttgaaatt tagtcttatt atcaatgtca gctaacggaa caccatttat caagatatct
    39361 caccctcaat attttgctct cgaaaataag gcttatggca gtaacttgtc atagccttat
    39421 ttttatcact cagcctactc tgctctaact gctctttttg cttctaggaa gtcaaatggt
    39481 aaacagttgt ctaattgcag aaatttcgag atacttgtta gtaaggaggg ggttttatgt
    39541 atcacgttca tttgattgat gctattccag aacaagagat agaaaagtta caaggggaat
    39601 atttcaaaat aatagatgat ttgccagccg aaggaatagt tattcgtagt acgaaagtga
    39661 aagatgaatg gcttacacca gatttgctag caatttcaag agctggtgtt ggggtgaaca
    39721 cgatcaacgt tgaaaaagct tctgaaaacg ggacgatcgt catgaataca ccaggtgtaa
    39781 atgctaatgc agtaaaagag cttgttttgt gctgtttgct cttatcttcc cgtccgataa
    39841 tcgaagcaag tcgtatggta caaacactaa caggtcctaa tattttagaa caggcagaaa
    39901 acaaaagaag tgcttatgtg ggacgagaat tgcaaggcaa aaccatcggt cttcttggtc
    39961 ttggagcgat aggcacaaaa gtagcgctaa gttgctatag cttagggatg gatgtcttgg
    40021 gttattctat ccgcgatgcc cagttggatt atgttcggca agcagattta gaaacagttc
    40081 tttctacctc ggattacatc gtagtcatgc tgccgttgac agaagataca aaaggattga
    40141 tcgatcaggc gaatatagaa aaaatgaaaa aagatgctgt acttatcaat gtaggaagaa
    40201 gtgaaattgt tgataaatat gctgttatgc aagcattgga aaaacaacat ctggctaaat
    40261 acttgactga ttttccagaa gaagagttct tagaaaatga ccgtatactt atgttgcctc
    40321 atctaggggg atcgactcag gaagctttgg cagacagcgg acgtttggca gttgaagcct
    40381 taaaagatta tcttttgttc ggtacggtta gagaagcggt caattatcca tccgcacgaa
    40441 tgtttttcca agcgccgttt cgattcacta tattttatca aaagaaaacc aatatattag
    40501 cagagatatt ttctctgctg aatgagaacg agctagcgat cgcagatata tcgcgtaacc
    40561 ataagaatga gcatgtctac atattgattg acatagacag tactgatttt gaacagctca
    40621 atcaagtgaa acaacagcta gaaaaaattt ctggagtacg aaaggtccgc ttattaaaga
    40681 aaccagaaag gccataaaga aagagaatat ttggatttca ttaattcttc tttccgttct
    40741 ttactttcga atttcgtaca actaaaataa gagaagcaac attcttttat tgatagaaat
    40801 gaaggagcaa gcatttgaaa agatatataa gcagactttc gaccaaacag aaaaagattt
    40861 taaaaggaac agcagcaatc atcagtatct tttttcttgt tgtttttagt aatttatttt
    40921 tgcagtggtg tcaaaatgat ctatccgtag accttgcgtt gaaatttgct ttttcttggc
    40981 atacggaaaa attcttctta gcctgtctcg tcttgctgat tattcttatt tttctgattg
    41041 cactagcagg atctgtccct ttaggttccc ttacgtatgt cgtagccatc ggtgtattag
    41101 gttttgcaaa ttatatgaaa atgagttatc ggcaagaacc gatttatcca gacgatttga
    41161 agatgatcac tgaaatcgga ttgctgaaag atatgaccgg cactatgctg tttacagtga
    41221 tcttagctgc cgcaggaacc gtgataggat tgttttgctg gtacatgttt cgaagcctga
    41281 aaaaaggaag gcgattccaa ttgatccgat taacgacact gcttgtggca attggactgc
    41341 tagggtatat cagtaatttc aacaatcccg ataatttgtt gcgaaaagca tataataaaa
    41401 cggcactatg gataccttac agccagaaaa tgaactacta taacactggt tttatcggtg
    41461 ggtttttgta caatctgaag gtagaaccaa tggatgaacc tgaaggatat tcgaaagaaa
    41521 agatcaaaga aatcactgaa aaataccaga agctagccga tgaaaaaaat aaaactgtag
    41581 aggaagagtc gccgaacatc gtgttcgtga tgagtgaaag tttctcagat cctagtcgat
    41641 taaacggcgt agaagtatct ggtgagccat tggcagatta ttatgaagta gctgatcaaa
    41701 catatagtgg caatatgctt tctcaaaact atggcggtgg aacagcaaat atcgaatttg
    41761 aagcattgac tggtttttct atggcgttat ttaatgcgca actcaccacc ccttacacga
    41821 tgcttgtacc aaaaatggat cagcttcctt ctatcgtttc agcgttaaac gcacaatcat
    41881 accagacgac agcgatccat ccatacaata cttcgatgta taaaagagag gatgtttatc
    41941 agacattagg atttgaccag ttcatcagcg agcgtacgat gacctatacg gatacgatag
    42001 agaataatcc atatatttct gatgagtcag cttacaaaga agtaatgaca cttctcaagg
    42061 aagaaaaaac acctcagttc attcatttag tcacgatgca gacacatatg ccctacgatg
    42121 gaaagtatga taatctagac tatcctgcaa aaacttcaga tggaagtggg acacttgact
    42181 tagagaatta tctgcaagat atttcctata gcagcacggc actgaagcag ttcacggaag
    42241 aattgaagaa tctttctaga aggactttag ttgttttttg gggggatcat cttccaggga
    42301 tctattcaga tacgatccaa gcaaaaaatg acaaacaaac attgcatgaa acacaatttc
    42361 ttatgttcga cagtaaagga gaattagaaa agcaaacgac tcacgatgca atcaccagtc
    42421 cgttttattt tgcagcgaat ctaatggaac agacgaatca gacaacaaat ggcttttatc
    42481 agctgctttt atcattagaa caggaacttc cggcgtttga acgagaactg tactatcaaa
    42541 acggacagtg gtataaagaa gcgcaattca atcgctcgca acaagagatt tacgacgaat
    42601 atcaattgat ccaatatgac attgtcgcag ggaaacaata tagtttagca gatggtttct
    42661 ttgagcacga ataagaatgg cgagctgtat agaaaccatt aaattttttc aagtacttgt
    42721 catttgagga taaaaacaag tagaataaat aataacaaca atggagaaag taggaaaacg
    42781 aacatgttac cgaatattgg ctattatgtg cagtccatcg atcaaatcgt caaggaaaca
    42841 gaagcaatcg gagaaggaat gcatccgaaa tatgaagtga tcagaaacgc aattgatgaa
    42901 ggaaaaacaa gtgaactgga caaatcgact cttgaagaga tcatcctgtt atttgaagaa
    42961 ggaacaaaaa aatatcgggc aatgcttaag aaagtcagta ctttgcgtcc accagcaaaa
    43021 gcaatgggca ttcataaaaa ttttgaaaaa gcttatcttt catatgtagc aggctgtgaa
    43081 gaaatgatcc aaagtatcga tcttgaatca ggggtagatg aagatctatt caatacatct
    43141 gaagcaaaac aagaccaagc gacagaccaa ttgacagctg ccatccaaaa aatgactaat
    43201 ttgttgttga aaaaataaaa gaaatctttg ataacaataa aaactagagt tatctaatat
    43261 aaatgtaata ttacctttat gatagagtga tcaaaatcct ttatgataat gacataccta
    43321 taaccaacaa caaccttgta cttactcaaa atcgagtaaa tactcctttt ccgtcgagtc
    43381 taaccatctc ggcggttttt tatttgtaga aaagaacatc aggatagacg gaaaagtctt
    43441 gtcctgatgt tcttttcaga tagtatggaa agctgattag ttttctacat tctgtacata
    43501 ttgttcaaag tagttctgta aatcggcttt gagtttctga tattcctctt cgctatactc
    43561 tttatcttcg attttcccat caaagaaagg aatatttagt tcttcccgta gtctgtctaa
    43621 tacgtcttgc tgattcattt cattctcctt ttcttactaa cgatcaaaat aaacacagac
    43681 acattctggt acatagacat cttttttcag taattccagt aatcctgttt caggatgacg
    43741 gcgatataat gtcagattat cggtgttctg attggcacac acgacaaaat tattgcttgg
    43801 atctagtgcg aaatcgcggg gaaaatcccc ttctgttgag atgatttgct tgttttgaat
    43861 gtgggaacca tcttcaaaaa ctgcgaatac agcaatcgag ttatgtcctc ggttagaagc
    43921 ataaaggaac ttgccatcat ttgaaatgcg gatagctgcc cctccatttt caccgtcgaa
    43981 ttcttctggc aaggtcgata ttttctgtaa ttcttcaaaa gcacctgttt ctttattata
    44041 agaaagcacg cggactgtgc tgtctaattc accaaataaa taagcgaatt gtccatttgg
    44101 atgaaagaca agatggcgag ggcctgttcc tggctctgca gtgaaggtag ttacaagatt
    44161 caatttgccg ttttcggaca catcataagt atacacacga tctgtaccaa gatcacatac
    44221 gactaatcgt tggtcaggag tcagatccgt atagtggaca tgcgcatgat cttggttttt
    44281 atgaggacct gtcgcttctt gatggaatat tgaatctgct gctttcagtt cgccatctcc
    44341 taatatatgg tagacattta cttcaccttt atgatagttc gccccgtata gtaattgacg
    44401 tgcttcatca accgctacat aacacaaagg agcgccagac tctgttaccg cattcaaaaa
    44461 atgaaaatcc ttatcgtacg caccggcacc acctaatcca tccacactag taactgtgta
    44521 aagattgcca gctttacttt ttgctacata ggtagggcta ttttcttcaa cagctaatga
    44581 aaggttggct aattcttctt tttctgtatc aaggtcgatc gtatagattc ctttactttc
    44641 gcgacgcgta taggttccta aaattatctt ttcgatcata tgagctgatt cctcctaatt
    44701 gtaatgaaat agttttcgtt tttattctat cacataatta ttccacacgg ctaaagaatg
    44761 agaatgtgtt atactgtttt tgaaagcaat taaaggagag agtgcaatga ttcaggcaaa
    44821 gattacagaa attgggacag aagcaataaa caaggaagaa cccatgctga ttttgttcga
    44881 taaaacagca acagctgcct tacgaaaata ttcggtgatt caagaagtat caaaagacga
    44941 acctttttct ttgaaagcag gcggaacaat tgcttttgat gatcaggtat atacgatcga
    45001 ttatgtcggt ccgatggcca atgggaattt agagacagta gctcacgtat cattgatttt
    45061 tgatgcttgt ccagaagaag gacaaattgc aaatggaatc tatcttcatc cgcatagact
    45121 gcctgctatt ggtttgggaa gccaaatttt ttataactaa caggaggaat tatggaagga
    45181 aaaaataaga agaacagacc ggtatcgtgg ttttggcgct ggtttttaaa taatcaagta
    45241 gtcacagcct tacttgttgt attgttaata ttgctgatcg tctttttatt tacaaaagtt
    45301 tcatatttgt ttgcaccaat ctggcaattt ttagcaatcg taggtctgcc tatcatttta
    45361 gcaggaatct tgtattactt gatgaatccg gtagttgatt actttgaaaa gcgaaaagta
    45421 ccaaggcttt acagtatcat tgggctgttt gttttggttg ttgcactaat cgcatggggg
    45481 agcgtagtga tcatccctaa gattcaggaa caaacagtga gcttcatcag taacttccct
    45541 caatatgtag atacgattga taataaatta accgagattt tgcgggaccc gctgttcaac
    45601 caatttcgcg aacagttgga aacagcaggt gataagttca tgaattcggc aggcgatatg
    45661 atccaagata tatctaagag tacagttcag agtcttggaa gttttgtcgg cgcggtagcg
    45721 actattttag tggctctgct gacgatgccg tttatcttat tttatctatt gaaagacggt
    45781 aaacaattag caccttattt tgtcaaattt ttaccgacac gcatgcaaaa accgacgttg
    45841 aatgtgctga gtgaaatgaa tagtcaagtt tcttcttata taagaggaca actaactgtg
    45901 gcttttgctg tggcaatcat gtttatgatt ggttttgcgg tcattggttt agagtatgct
    45961 gtcacgttgg ggattattgc gggttttttg aacctgatcc cttacttagg atcattttta
    46021 gcgatgattc cggctatctt tttagccatt gtagcaggtc cattcatgat catcaaagta
    46081 ctgatcgttt ttgcagtaga gcagacaata gaaggacgct tgatctctcc attagtacta
    46141 gggaatcagt tagcaatcca tccagtaacg attttattag ttctgctgac ttctgggaaa
    46201 ttgttcggaa tcatcggtgt gatcttgggg attcctgttt atgcagcagc taaagtagtg
    46261 attactcatg tttttgaatg gtacacaaca atctcttctc tttatgaaga aaatccgttg
    46321 aaaaagcaga aagaataaca aaaagagaca gatgggaaaa tatccaaggt acaaatgctg
    46381 ctttgaagat tttttcctct gtctcttttg tatgcattta tctcaatttt taaaatgatt
    46441 tacctaaagc agcagcttta tctaatgcat tttgcatcaa ctcatctgca cggtcagggt
    46501 cataatcgat tccttcgatg aatagctgat ctacttgatc gatgcctaca aagtttaaaa
    46561 taccttttac atattgagag gcaaagtctt gtccgttgta tacaccgcca ttagattgga
    46621 tgtgcagtgc ttttttacct gtcactaatc cttctggccc gttttctgta tagcggaacg
    46681 tttttccagc tacattgacg gtatcgaacc aagcttttaa ttttgttggg atatttagat
    46741 tccataaggc gtttgcgata acgattttat cagcagcaag gaactgatca gtcaattcat
    46801 tgaaacgagc aattttttgt tgttgacttt ctgataagga agtgaattct gcaccagcac
    46861 gtaatgcttc ccaacctgat aataattctt catcgatttc cggaatatca tcgcgataaa
    46921 gttccaaaac agtcacttca tcatctggat gattttcttt ataacttgtt aaaaaagacg
    46981 tcaatgcctt aactgtgcgc gattcttctg cagttagggg atgacctttg actactaaaa
    47041 cagatgccat atgcttacct tctcctttta ttgctatgat tgttataact atgagaaaaa
    47101 gaaaaggcta tcaagtcata ttgataaggt tgaagaataa ataactaaaa aaagacaggg
    47161 tataaaagag gctgtgacac gattttttgt cacagcctct tttgaatcta acaagcaata
    47221 ttcaagcaac actcgactga agagcttcca tcccaccaat gatataaaca gcacgaaaac
    47281 cattagcagt aagttgatcg gctaatgctt ctgatcgcct gcctgtatag cttagaatat
    47341 aataaagttt ctttggatct agatttttta attgtcttgg caagatagca gcggggatag
    47401 aaagcgagtg gcttaagtgg ttttttgtgt aatctaaggt atttcttgta tctaaaacga
    47461 tgctgtcagc atcgagaggc aatttattga agtcttggac actaattgat tgggccattt
    47521 atctcatcct ttgtttagta tgtggctatt ttaatgggca actctcatta attcaaatgg
    47581 aaggattcct cttatcactt ttttaatgta tcggatgata atgaaaaaaa ctatgcaaat
    47641 gtcttgcaaa acaggtagga ggtgttataa tgacacagcg tcatatgaca atgtgtcatc
    47701 ttgaaagaaa ggaggatcca tatgccgaca cagacatttt tccatttgcc taaagaaaaa
    47761 caaaaaagac taatcgaggc tgcgagaatc gagttttcta gagtaccctt aaaagaagct
    47821 tcgattgcta atatcgtcaa attagcggat atccctagag gcagtttcta tcagtatttt
    47881 gaagataaag aggatcttta tttttattac tttgagacaa tgagacgtga cagctctaaa
    47941 gatatgttac aactaatgaa agaatccgat ggtgatctat tcaaaggatt cgaatcctat
    48001 ttttctaaaa tgatttatga gattttggaa ggcgagaatg cttcttttta tcgtaacttg
    48061 tttatgaaca tggattaccg tgcctcaaga aaagtcgctc ctcatacgag tcgccaaaaa
    48121 acgcctcacg atccacataa agaacacaaa caagatgcaa aagagttgct tgaattgatc
    48181 gatcggacga agctgaaagt aaaaaatgat catgaattgg aattactgat ccaattagtg
    48241 atgaatactg tatttacaac aattgcgcat tcgtatcgct tattttcaac atctgaagat
    48301 tactcagtag agcaagcaat cagtgaattc aatttgaaac tttcttggct gaaaaacgga
    48361 gtatataaat agaaagaagg gaactagatg ctaaaaatcg taaaacggat ctccttgact
    48421 tcagcaattg cagctgcagt tttcatggtg atccaagtac tggcagattt atatttgccg
    48481 acacttacct ccaatattat tgataaaggg gtagcgcaag gagatgtcga ttatatttgg
    48541 catacaggtt ttgtgatgat cggcttttct ttgatcagta tcttagctgc tatcgcaaat
    48601 acattttttg ctactcgtga atcacagaaa ctgggtaagc aattgcgtac ggatgtctat
    48661 aaaaaatcag agagtctgac aaaagatgcg tttgataaat atggaacggc ctctttgatc
    48721 acaagaacga ccaatgatgt gactcaaatc caaatggtta cacaaatgtt tttacgtatg
    48781 atgatcaatg caccaatcac gttgattggc gcgagcatac ttgcttatca aaaagatcat
    48841 cagttgacaa aaatcttctt agttgtcatc ccagtaatga ttattttgat cggcggaatc
    48901 atgtactttg ctgttccatt attcaaaagt atgcaaaaga aaactgaccg tttaaacctg
    48961 gtatttcgag aaggattgac aggggtcaga gtgattcgag cattcgataa gacacgcttt
    49021 gaagaaaatc gttttgattt agcgaataaa gattatacaa atacggcaat caaagttaat
    49081 acgatcgtcg cattgatgat gccaatgatg acattgatca tgagcggtac aaacgtagca
    49141 atcacttggt ttggtggaca ctacatagca gatatgactt tggaagtcgg taatctgatt
    49201 gcatttatga cttatgcgat gcagatcttg atcagcttta tgatgctttc cgctattttt
    49261 atcatggtgc ctcgtgcaca agcttcagct gaccgtatta atgaagtgtt ggatgaaaaa
    49321 atcggtatcc atgaccctga aaatcctaaa acagtttctt ttgctggaaa aaacgcaaca
    49381 ttggccttca atcatgtcaa ttatcgatat catggagcag aaaaacttgc attggaagat
    49441 attgatttcc aagccaagtc gggcgagatc gtcgcaatca taggggggac tggttcaggt
    49501 aaaacgacct tagtcaattt gatccctcga ttatatgaca tcgaatctgg ttcgatccaa
    49561 ataaatggaa cggacattag tgacatgact caatataatt tgcgagaatt aatgggcttt
    49621 gttcctcaaa aagcagttct gttctctgga acgatccgag acaatatgca gtatggtaag
    49681 ccggatgcaa cagatgaaat gatttggaaa gcattagaaa tcgcacaagc taaagatttt
    49741 gtttcagaga tggaagatgg cttagatagc catgtggaac aaggaggagg aaacttctct
    49801 ggtggacaaa gacagcgtct ggcaattgca cgggcattag tcaaaacagc agatatctat
    49861 gtgtttgatg attccttctc agcgttggat ttcaaaacgg atgccaatct tcgccaagca
    49921 ttgaaaacga atatgaaaga aagtatcacc gttttagttg ctcaacgagt aagtacagta
    49981 atggatgcag atatgatcct tgtgctagat gaaggaaaac tggttggcaa aggaacacat
    50041 gaagaactat tagcaacaaa cgaaacttat caagaaatcg ttcattcaca actaagagag
    50101 gaggacttag catgagtaaa acaaacacac gtccctctca tggaccagca ggcggtccag
    50161 gacatggtgg acctggcaga aatctcggtg taaaaggtga aaagcctaaa aatttctggg
    50221 gaacggtacg ccgattgttt ggctatatgt ctaaacgtat ggttgcgatc atcgctgtat
    50281 ttgtactagc aatagcagcc gtgatcttcc aaatccaaac accaaaggtc ttggggaaag
    50341 caaccacaga aatattcaaa ggtgtaatgg ctggcgctca acagatgcaa caaggccaac
    50401 aagtaacaaa atttccgata gactttgata aaatcgcgca gatcattgcg acagtaatcg
    50461 tgatgtattt gatttctgct gtattcaact ttttacagca atttattatg acacgtgttt
    50521 cccaacgaac agtttatgaa ttacgtcatg atttggaagc caaaatgaat cgtgtaccga
    50581 tttcctatta tgatacacat acaaatgggg atatcatgtc tcgagcaatc aatgatatgg
    50641 ataacatcgc aagcacgctg cagcaaaatt tgactcaatt tgtaactagt gcagtcacat
    50701 tgattggggt catcgtgatg atgctttcaa tcagctggca attgacgtta gtcgcgttat
    50761 tgatgatccc tttaagcttg atcatcgtga tgatcgtagc gccgaaatca caagtgtttt
    50821 tcgcagatca gcaaaaaagt ttaggtttat tgaataacca agtagaagaa acatatggtg
    50881 gtcataccat tgttaaaaca ttcaatcata ctgaaaaaga ccaggaagta tttgaaaaag
    50941 aaaatcagaa tctgtatgcc gctggttgga aagctcaatt tatttcggca atcatcatgc
    51001 cgttgatgaa tttcgttaaa aatctaggct atgtgttcgt cgctgtacta ggcggagtaa
    51061 aagttgcaaa tgggaacatg acattagggg atgttcaagc gttcttgcaa tatacaacac
    51121 agttctctca accaatcact caacttgcaa gtttgatgaa cactatccaa tcaacagttg
    51181 cttcagccga acgggtattt gaagtgttgg atgaagaaga gatgtccaat gaaaaatctg
    51241 gccttccaga agaaaaagat acaccataca aagttcgttt tgaaaatgtt caattcggct
    51301 acacaccaga taacttgcta atgactgatt ttaacttgga tgtcaaacct ggtgagatgg
    51361 tcgctattgt aggtccgact ggtgcaggga agacgacact gatcaacctt cttgaacggt
    51421 tctacgatgt ttctggaggt agtattcgtt acgatggtgt agatacccgt gatctttcac
    51481 gtgatgaatt gcgcgcacag ttttcaatgg tactgcaaga tacttggctg tttacaggaa
    51541 gtatctatga caatatcaaa tatgggaacg acgatgcaac agacgaacaa atcattgagg
    51601 ctgctaaagc tgctcacgta gacgattttg ttcgtaaatt gccagaagga tataacactg
    51661 tattaaacga ggatgcaagc aatatttcgc aagggcagcg tcagctaatc acaattgcgc
    51721 gggcattctt agcaaatcca gatgtcctga tccttgatga agcaacatct agtgtagata
    51781 cacgaacaga aatactgatt caaaaagcga tgaaccgcct attggaaaac cggacaagtt
    51841 tcgttgttgc tcaccgcttg tctacaatac gcgatgcaga caacattatt gtgatgaatc
    51901 atggttcgat cgtagaaaca ggaaaccacg atacattgat ggaaaaagac ggattctatg
    51961 cagatcttta taacagtcag ttttctgaag aagaagcttc atagaatagt acaaatttat
    52021 tatttttttt aggggctgtg acaaaagtcg tgtcacagtc cctttttccg aataaacggt
    52081 gttcaatcag
//
LOCUS       DAFLWQ010000297        16776 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.guided.065, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000297 DAFLWQ010000000
VERSION     DAFLWQ010000297.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16776
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.guided.065"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            367..1230
                     /locus_tag="L1V16_003238"
     CDS             367..1230
                     /locus_tag="L1V16_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBN1277472.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            1330..1812
                     /locus_tag="L1V16_003239"
     CDS             1330..1812
                     /locus_tag="L1V16_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBN1277473.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(2075..2542)
                     /locus_tag="L1V16_003240"
     CDS             complement(2075..2542)
                     /locus_tag="L1V16_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBN1277474.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            2665..3516
                     /locus_tag="L1V16_003241"
     CDS             2665..3516
                     /locus_tag="L1V16_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1277475.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(3767..5725)
                     /locus_tag="L1V16_003242"
     CDS             complement(3767..5725)
                     /locus_tag="L1V16_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1277476.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(5722..6594)
                     /locus_tag="L1V16_003243"
     CDS             complement(5722..6594)
                     /locus_tag="L1V16_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1277477.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(6936..7808)
                     /locus_tag="L1V16_003244"
     CDS             complement(6936..7808)
                     /locus_tag="L1V16_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1277478.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            7936..8505
                     /locus_tag="L1V16_003245"
     CDS             7936..8505
                     /locus_tag="L1V16_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBN1277479.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            8572..9309
                     /locus_tag="L1V16_003246"
     CDS             8572..9309
                     /locus_tag="L1V16_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1277480.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            9540..10808
                     /locus_tag="L1V16_003247"
     CDS             9540..10808
                     /locus_tag="L1V16_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBN1277481.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            11295..11759
                     /locus_tag="L1V16_003248"
     CDS             11295..11759
                     /locus_tag="L1V16_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1277482.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            11743..12372
                     /locus_tag="L1V16_003249"
     CDS             11743..12372
                     /locus_tag="L1V16_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBN1277483.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            12726..14204
                     /gene="msr(C)"
                     /locus_tag="L1V16_003250"
     CDS             12726..14204
                     /gene="msr(C)"
                     /locus_tag="L1V16_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBN1277484.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            14251..14697
                     /locus_tag="L1V16_003251"
     CDS             14251..14697
                     /locus_tag="L1V16_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBN1277485.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(14896..15411)
                     /locus_tag="L1V16_003252"
     CDS             complement(14896..15411)
                     /locus_tag="L1V16_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBN1277486.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            15528..16730
                     /locus_tag="L1V16_003253"
     CDS             15528..16730
                     /locus_tag="L1V16_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1277487.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         5300 a         2988 c         3483 g         5005 t
ORIGIN      
        1 tgatgaggtt gaacttttac acaagattgt ggacttgact gcaaagaaaa atccaagcag
       61 cgttctgatc agcagtttga acaacaattt gctttgtaca gtaggtagta agcggattaa
      121 ctaagggaat aaaagatatt tttaccgctt tgtttactta gaatctgtct tccccaaaat
      181 ttatttttct aaaggtaaaa catagatagg cagataatac caattatccg ttacgaaacg
      241 ctgcttgaga attttcttta gatccataca acattttcta catctgacta aattggttcc
      301 tgattcatca agtaattgac tttctttgat aatatgataa aaaggcaatc aaggaggaag
      361 ataaatatgc ttaaagatct gaaccaattg atcgattaca tcgaagaaca tttgacagaa
      421 ggactttcct ataaaataat agccgaaaat acaggaatct ctgaatatca attaaaacgc
      481 atctttacgt ttattgcagg gatgtcgcta atggactata tcaaaaaccg tagattggct
      541 ttggctaatc gcgatcttct agatggatca agagtgacag aaacggcgtt tagatatgga
      601 tatgaaacag tcgaaggttt ttcaagagct tttcgtgatt ggtcaggata tctgccttca
      661 gaaatcagca gatacggcat acaaaaatct tttccacgct tgacattttt tattgatgtc
      721 agaggaggaa aatcgatgga atttcgtatc gaaaagaaag aacagtttta tgtggcaggt
      781 gtggcgaaaa aagttcctgt caaatttgaa ggagtcaatc aagaaataca aaagttagcg
      841 cagacgatca cggagactca aagggaagag atgcataagt taggagattt atatccaaat
      901 caagtaatca acgtttctta tggatttgat ggagaccgct tggaagaaaa gggcagtttg
      961 atgcacatga ttggctttgc tacgacaaaa gaaaatccgt acgctgattt agaaatgctt
     1021 gctatagaag aacacacttg ggccattttt cctaataaag ggccatttcc ccaaacttta
     1081 caagatactt gggggaaaat ctatgcagaa tggcttcctt cttcagatta tgggttagtc
     1141 gaagctcccg agatctcttt tacaaaatgg ggagaggatt tcagtaatgt ttacagtgag
     1201 atttggattg cagtgaaagc aaaaaaatag ttaaaaaata aaaatatccc tagaaaaaag
     1261 agcgtaatcg tgtcatttcc ctttaatttt atgtaagatg aacttaatat aatagaaagg
     1321 gtgggagaaa tggcaaagta taggatcgaa gaaaaaccag attttacggt gacgggtatt
     1381 ggtgtggaat tgaagagtag caatacggat tttgtcggtt tggctgcaga gaaacaagca
     1441 tttgagcaaa aagttatcgg taatggaaca atagatgcat tgaaacaagc tgctgaaaat
     1501 cattatttct ttacagtcaa cgaaccctat aacgggaaaa tgatgtacta tgtcggtgtt
     1561 caaacgagtc aggatgttcc aaacactacg cgaatcatcc cattcccaaa aggaacgtat
     1621 cttgttgtaa gcgctttagc agaatcgcct gaagaattaa gaaatgattt gacgaatacg
     1681 gcctttgggc atgttttaag agaagtagaa gattacgcct atgttggggg tccaaatgct
     1741 gtagtcgaaa tgggagttac caacgggaaa tatatgggag aaatctggat accggtagtc
     1801 aataaaccat gataatatag aggtcgtgaa agtagcgctt tgacctgagc attagagagg
     1861 aaaaatggga aatagctttc catattttgc atttttcaga actaatgccg agggtcagct
     1921 acttgaacac cgtttatcaa gacgtcatga cttcagcgct ttgacctgag cattagagag
     1981 gaaaaagggg catgacaagg cttttgtccc ccggagaata aaagaattta tgtagacgat
     2041 tccgatcaga aaaatgcagg cacagtagag agaattataa aaatctctct acgaggcctg
     2101 tgttttctgg tcttttttct ttttccaaaa cggctatttt atgtatcaga ctatcaagtg
     2161 tgatcttagc catttcttct tctgcctttt tctgcagccg agcgtagctt tcttctaaag
     2221 cttcttggat attcgcacca acgacgcaat ttggatttgt ttttggatcg acttggataa
     2281 gctgtgtatt accttcgatg ctgcgataga catctagtaa agaaatctga tctggacttt
     2341 tggcaaggga aggctgcggt tttccggttt ttgtaaagat caaaccggat tttttgagct
     2401 gactcatgat tttacgtaca tttgctgcat ttgtttcgat actactggca atcatctcac
     2461 tagaaagtga tcgggtatct tgaaacattt caatataggc aagtacatgg attgcatcac
     2521 taaattgcag agaatacttc atcagttgtc atcctttcat tttttttgct tgacttatct
     2581 taccacactc tttatgataa aggtgtaatt tataaatgta cagctgtaaa tcttaacaaa
     2641 taaaaagaat agggagtggc aaatatgcat tatttagtaa caggagcaac tggaggtttt
     2701 ggtggttatg cgctggaatt cttaaaaaag atggttccac aaaatgaaat ctatgtacta
     2761 gtacgtagtg aagaaaaagg agaagcactg aaagaagctg gatttaatat acgtattggt
     2821 gattatgatg atttagactc aatgaaagaa gcgttgaaag gaatagatcg attgcttttt
     2881 gtctctggcg ttccaggaaa tcgtcaagcc gaacataaga atgtagtgaa ggcagcacaa
     2941 gcagctgggg tatcttatat cgcttataca agttttgcag atgccgatca ctcgatcagt
     3001 gtattagcgc cagatcacca attcactgaa aaaatgatta aggattcagg tatttcccat
     3061 acatttttac ggaataattg gtatgtagag aatgaattac ctatcattgg gcaggcttta
     3121 aaaactggtc aattcgttta tgctgcagga aatggaaaaa caggttgggc attgaaacgt
     3181 gaatatgcag aagctgcagc aaaagtacta gtagaaagtg actctccaga aatcttagaa
     3241 ttatccggca atctaactga ctatgaagaa ttagccaagg cattagagcg tgcgacaggt
     3301 aaagagttag aaattattga agcaagtgat gcagcgtttg tcgaaaatct aaaagaagcc
     3361 ggattccctc aagaagcagc tgacatgttt ttagcgatcc aacatgatat taaaaaggat
     3421 cagttagcta tttcctctga tgatttagaa aaagtattgg gaaaaccatt aacttctctt
     3481 gaagcagcat taaaagaaat attggatcag gaataatgta taaagaggtt gtgaaaaagc
     3541 cgattagttt tgagtatgaa gaaaaatttt gtgaaaaagc tgttctgcat caagtaataa
     3601 gaagagtcaa ataaaaaata gctcttcata tgtttcgttt agctggactt attaccgcgg
     3661 agttggcagg agaacgccgt ttttattcgg aaaaaggagc tgagacaaga tttttgtctc
     3721 agctcctgtt tgtttatcga taaaaaagtc tggggaagac gatggctcag gctttgttgg
     3781 aaacagagcc gattttatca tttgctttta catcacgtgc gggttcgatt tctaagcttt
     3841 ggactttgtc gccatttgtg aatacaacga ccatatccgt gtttttgcct gcagattgaa
     3901 tagcggcaag atcaactaaa gcaatcaatt gacctcttgc gactttttga ccttcttcta
     3961 catataaagt gaatggttcg ccttttaagt caacagtgtt gatgcccata tgaagcaaga
     4021 cttcgatacc agcatctgtt tggattccga cagcatgttt cgttgggaaa atgtttgtga
     4081 tcgtaccagc gattggagag aagatttctc cattttctgg taatacagca tagccgtcac
     4141 ccatcatttt ttccgcgaat acatcatctg aaacttcagt gattggaatc agtttcccat
     4201 ttgcgatagc gtaaatatct tgttcgatcg tttcaccggc aaatgtttct gttttaacca
     4261 cggtgtttgt ttgtgcaggt cgtgctgcag caccaccatg tagttttgcc atctcatctg
     4321 caacgaattg tacttctgta cctacgatga cttgcgcatt ttttccgtcg atgatcttca
     4381 taccaggtac gccagtggct ttgattttat tttgatcgat caggcctgta tctttgactt
     4441 gcaaacgaag gcgtgtagta cagttatcga tcgaagttac attgtcggct ccgcctaatg
     4501 cagcgtagat tttgcttgct tgtgccgcat atttattgtc tgaattagtc gttgcagtat
     4561 cgtcatctga aagatctgct tcctcgcggc caggagtcat cagatggaat tttttgatag
     4621 caaagttaaa gccaaagtag taaatcactg ctgttactaa tccttggacg atcaacatca
     4681 atggctgatt cgcaatcgga tttttcaaag ataggaagta atcgacaaat ccggcactaa
     4741 aggcaaatcc tgctgtccaa tggaagaatg cactcactgc taaagaaatc ccagtgaaaa
     4801 ttgcatgcaa gacatataat ggccaagcaa cgaacataaa tgaaaattca agtggttctg
     4861 tcacaccagt aaagaatgaa gcaaaagctg ctgctagcat caaggaagct gtttttgctt
     4921 tgttttctgg acgtgcattt ctgtaaatag catatgctcc tgctggaagc ccgaacatca
     4981 tgattgggaa aaatccagct tgatacattc ctgttacgcc ttttgttcct tcagaagcca
     5041 aaaatttacc aatatcattg attcctgcta cgtcaaacca gaacacggag ttcattgctt
     5101 gatgcaatcc tgtagggatc agtaaacggt tgaagaagcc ataaagacct gcaccacccc
     5161 agcctaaact caaaatgaat ttagcaaaag aaactaaagc agagtaaacc ggaggccata
     5221 cgagcagtag cactgcactg atcagcaaca tgacaaaggc agccaagatt ggcactagac
     5281 gcttgccgct aaagaaagat aaagccatcg gtaattttgc ttcgtggaaa cgattataaa
     5341 gagctgccgc aatcaatccg gcaataatac caataaatac gttactgatc tgagcaaaag
     5401 atggatcaac tgattctggt ttgatattca ataaagtagc tactgaatca gtttttaaaa
     5461 catttactgg aacttcaaat gcgaccaaac ctgccaaggc agcagcacct gatttgtcca
     5521 ctgacatccc tagtgctaac ccaacggcaa acagcaaagg taattgacct aaaactgcgt
     5581 taccgccagc ttgtaaaaaa tgagcgacaa tgtcgttact ataagatgcc caccagtttc
     5641 cgatccctac tagtaaagca gcagcaggta agaccgcaac tggaagttga agggaacgtc
     5701 ccattcgttg tagatatgct ttcaattttt ttcctcctca tgattgttaa catttgtttg
     5761 tacgattgcg cttcttaaac gctcgatatg gatggccaag taacccagtt cttctttcgt
     5821 gatcgcgagc tggtattctt tggtcagcaa cacacggatt tttttagaaa tcttatagct
     5881 ttctgggtat tttcgtttga ccatttctac gatttccgtg tctaaaacag catattgttg
     5941 cgcatgggtt cgttgtagaa gcagtcgtaa atgattcacc agtcttgaat aattcagtga
     6001 aaatggttct gaatggatat ctgtttccaa ttctgattcc actaaatgga tgatgtcaga
     6061 tacaatcgtc acttcacgga tactgcgatg gttattgttc cgaccgcttc gtccgctgtg
     6121 aatatggatt gcgatatatc ctgcttcgtc ataagtatat ggaatcccaa gctcttttgt
     6181 cagatactct actgcccatt gagcaatact gaattcatca ctgtaaagca cttcgatttc
     6241 tcttaaaagt ttgttgcgga tgacgatacc gttattaatg ttctccgcag aaaaagcaat
     6301 gtggtcggtc aaagcgatca atacatgttc attcaacttt tccatcaaaa cagtttccgc
     6361 atgatcaatg atcgtttctg ctgcaaataa aaagcgttca tcaatctgat taagtaaatt
     6421 ttgcaacttg atttgacctt ctggttccat gacaaatatc cgttcgacat cacgatcaaa
     6481 aatcaaatca tttctttttc tgtcaaatcc aatccctttt ccaatagcta ctttttcctg
     6541 tccaccgtca tctaccaata ctgcattttg attaaagatc tttttgattt tcatgcgcgc
     6601 accctttttg aagatttggt tttcacgttt gctagaccag ttgattgcgg ccaaacaaaa
     6661 atagacacga aaaacctcct agggaaacca tgttcctcag agatttttca tgcctagtat
     6721 gatctagtca catgaaacga attattgtta acgtaatcaa ttttatatag acagttatgt
     6781 tttgtcaatt ctttttttat aattatagta atttactgga attatcagaa ataaaaggaa
     6841 gaaataaatt aagaaactta tgttatttaa tcgttggatc ttttgcttat cttattcgtt
     6901 gttaaaaagc tgaaagcgaa ggaaaaaaac tctacttaac tgtatttctc cgttaggaca
     6961 tctaaaaatt tacgagcagc aggagaaaga ggctggtctt ttttccaaat gagattcagt
     7021 gaagcttgta atggcggatc gagtgggatg aatatttttt ccgtcccata agtattgatg
     7081 atcccatcta gagctaatgc accaaaagtc ccgttatcga ccatcaaaga agcattgtac
     7141 aataagttat atgttccgac gatcgataac tgatctatgc tgaaacctag ccattcagct
     7201 agttgactgt ccactgacgt ttgccgggaa atgatcaaag gaacagtttt cagttcctgc
     7261 ggatggatga cggtttgctt tgctaaagga tgatttcgat gtatcaaaag tccccaacga
     7321 tcttgggctg gcagtcgaaa tgactggtat ttttgtttgt ttgtcggttc gattacgagt
     7381 ccaaaatcaa gtaatccgct atccagtttg tctatgatat catctgcatt cccgctatat
     7441 aaatgaaact ggatatcagg atgcgccttg atcaacgaat gaaggctatc agaaatgaaa
     7501 gagattgctt tagtttcgcc tccgccaatg tagatttctc cagagatgat tgcgtcattt
     7561 gttaaattgt tcgccgtttt ttctaccaac gacaagattt cttttccttt tgaataaaga
     7621 tatcgaccag aatccgtcaa ctgtatctct cgggagcccc gagtgaaaag tgtcacacca
     7681 agttcttctt ctaaatcttt cagttgtttt gagagagtag gttgcgtgat atgcagagat
     7741 tttgctgctc ggctgatatt tttttctcta gctactgcta aaaaatacgt cagtatacga
     7801 atatccattt tttccctcct gtttttaaaa aagcatacca ctaagtatag ttaaaaggaa
     7861 tagttaagta tgttttataa gtattagaca tgataagccg tccgttataa agtaaggata
     7921 aaaggaggga gcaaaatgac aagcctcatc gaaaaacaaa tcgtcaataa agagattcga
     7981 gtaacggatc cgctctttga agtgatccat cagatccaag ctgaaaacga agagccttta
     8041 gcagcgctga atactgggta ccatgaacca gcagatatcc gcaaacggct agaaaatatc
     8101 attagtgaca aagtagatga tacggtgact gttctgctgc ctttttatac agatttcggc
     8161 aaacatatta gtatagggaa aaatgtcttt atcaatcgtc aagtgatgtt cgttgactta
     8221 ggtggcatct gtttagaaga ttcagtattg attggtcctc gtgtcaacct catcacggtg
     8281 aaccatctaa ccgatccaaa agaacgaaga ggcttgttag taaagccaat ccacatcaag
     8341 aaaaatgctt ggatcggagc aggagcaact attctgccag gcgtaacgat tggcgagaat
     8401 gccattgttg cagcgaatgc aactgttacg aaagatgtcc cagacaatac catcgttgca
     8461 ggaatccctg ccaaaatcgt caaacctgtc gaacggatta tttgaacagt aagatgaaat
     8521 aagagatagt gagtataagc aagagatttt tcaaaacagg aggagaatag aatgaatgat
     8581 ttatcagaaa aagtgattgt catcatgggc gcttcaagcg gaatcggtga agcaacaacg
     8641 aagctattag cagaaaaagg ggctaaacta gttatagctg cacgccgaga agatcgccta
     8701 aaagcaataa aagaatcttt accagaagct gagctatata ttcaaacagc agatgtaaga
     8761 gattttgcac aagtccaagc agttatcgat ttagcgatgg aaaagttcgg tcgaatcgat
     8821 gtattgtaca ataatgcagg aatcatgcca accgctccat tagttgaagg tcaccgtgat
     8881 gaatggcaaa atatgcttga tatcaacatc atgggtgtgt taaatggaat ttccgccgta
     8941 cttccaatca tggaaaaaca aaaatctggg catatcattt caactgattc tgtggcggga
     9001 catgttgttt atcctgattc cgccgtttat tgcggaacaa aatttgctgt ccgtgcaatc
     9061 atggaaggat tacgtcaaga gcaacggcaa aataacatca aatctacgat catctctcca
     9121 ggagctgttc aaactgaatt atatcaaacc atcagcgaca aaaaggctgc tcttgaactt
     9181 catgaagcgc aaaaagaatg gggattgacc tccgaagata tagcttctgc tgtagcattt
     9241 gcgatagaaa cgccagaccg gatgtctgtc agtaacatga ttatccgtcc gacgacacag
     9301 gaagtataat ccataacgga taatatccaa agagaattac ttgttaaata gttattcaaa
     9361 cgaccatcaa tttaaggcgt gaatggagaa gaatattctt catttacgtc tttttatgta
     9421 gaaaaagcaa atttatcaaa aagaaacaaa tgttatttaa atatggacat tgacttgctt
     9481 ttactttttt agttacactg ttatttagga aaagtttcat aattcaaagg agaaaaaaga
     9541 tgaaagcaaa gaatttatta tttagcgtta ttcttttagg aaatctagca gttgccaaca
     9601 caacagtgct agctgaagaa tcgacagaaa ctgtcgcaac tcagacatcg agttcttcag
     9661 aaacaggaat tgaaaacgat acagagagta ctttgcagtc agctactgtc tcagaaaata
     9721 caatttcaac cgaagaacca acaactgaaa caacagaaca aacacaaacc gaagacagta
     9781 catcagcaga agctcagaac aatccagaga atgcagaaga aatcacgaac caattgacag
     9841 atgggcaaac attgacacat acccatcaag cagatttgtc tgaattcgaa aactatactg
     9901 gctatgcttt ttatgctcgc tcatctgcta attctcaaca agcgttcatt gatagtattg
     9961 cctcaactgc acaaagtttg gcaagtgcca atgacttata tgcatcagtc atgattgctc
    10021 aagccatcgt tgaaagtggc tgggggaaca gtactttggc ttctgcccct aattacaatc
    10081 tatttgggat taaaggaagc tataatggcc aatctgttac gatgcctact tcggaatatg
    10141 tgaatgggca atggattacg gtgaatgccg cttttagaaa atatccttcg tacaaagaat
    10201 cattgcaaga taacgtaacg gtattgaaga cgacttcttt tcagccaggc gtttactact
    10261 attccggtgc atggaaaagc aatacgaact cttacaaaga tgctacggct tggctaacag
    10321 gtcgttatgc cactgcgcct aattatggtt ctacattgaa caatgtaatc gaaacctata
    10381 atctgacaca gtatgataca gcaccaactt caacttctcc gatgtatcgt ctgtataacc
    10441 gtcatacagg agaacattta tatacattga atgccggaga aaaaaattat ctgccaactg
    10501 taggctggga atatgaaggg attgcttggc aagcaccaaa cagcggacaa cctgtctacc
    10561 gtttatacaa tccttacagt ggagaccatc attacacaat ggcacaatct gagatcaact
    10621 ctttaacaaa aatcggttgg cgttatgaag gtctaagttt ttattctggt ggttccaagc
    10681 caatttatcg actatttaat ccaaatgaaa aaactggtac ccatcactat accttgagtg
    10741 ctaaggaaag agattggcta acaccgatgg gctggagata tgaaggaata ggattttatg
    10801 gttattaaaa agaggtagtg aaaaagctgc cctgcatcaa gtagtaagaa cagccaaaca
    10861 aaaacagatt ttcatgtttt ttgtttggtt gaacttatta ccgcagatgc aagtttttga
    10921 acaccgttta ctcaaaaaag gttgtgacaa catcttgtca taactttttt attactgttt
    10981 aagcatactg atccaatttc taatattcga cgggattctt gcaaaaggcg atttcggaaa
    11041 tttttggcgg tgtaaaattt tctactgcag aagagctatc ttctatagtt tgataagaat
    11101 caataatctt ggttttagcg ttgtgctttc tttatcattt tttccgttca ttctacaaaa
    11161 aatttctttt ctctatactt ttctattgag agcgtttttt ttattacaca gctgattctt
    11221 tgactttttt ctttttttat tctattattg acaagtcaat cgttgacgag tcaattatta
    11281 gaaaggagga aattatgtct ttagaagaga ttagtcacct tttatatcaa atcaaattag
    11341 ccgatcaaaa aatcgtccag atctttgaag aaaatatcgg tataagtctt actagatacg
    11401 agatcatgat gagactgaaa gaagaaaatc cattgctaca aagcagtttg caagaaaagt
    11461 tgcagattga tcaaggagca gttactcgtc atctgaaggt attggaagca aatggctatg
    11521 tttcgcgtca gagaaatcct cagaacaacc gggaagtgta tgtagcgcta acagaaaaag
    11581 cccagaagaa aatcgagcat tgtgaaatgg accataaaga tacaggttcc gtgctatccc
    11641 cggctttcag cgatgtagaa atgaaacaat ttctaacact tttagataaa ttgaataccc
    11701 aactttgcaa tataacaaca gaaacgaaag aggttaataa taatggaaca aaaaaatgat
    11761 ttttcaacaa ttatgactgg tagaagatcc gttcgcgtat atgatgaaac atacaaaatc
    11821 ccacacgaag aaatgctgga aatgatcaaa gaagcgacga ctgcaccttc ttctgtcaat
    11881 atgcaaccat ggcgctttgt ggtcgctgaa agcgaggaag caaaagaaat cttgcgtcct
    11941 ttgatccgtt tcaatacgag acaaaatgat acttcttctg caatggtcat gatttttggc
    12001 gatatgcaat gttacgaata tggcgaagaa atctataacc aagcttacga atcagggaag
    12061 atgccaaaag aagtcagaga tcaacaatta gctgcgatca ttccttatta caagagtttt
    12121 tcaagagaag aaatgaacga tgtagtcaaa gtcgattcta gcttagcggc tatgcaattc
    12181 atgttagttg cgcgtgatca tggctatgaa acaaatccaa ttggtggagt cgaagcagat
    12241 cagttggcag aggcatttgg tttggataaa gaccgttatg ttccagttat tattttatca
    12301 ataggaaaag cggtagaaga aggttacgag tctgttcgtt tagcaccaga aaagatcact
    12361 acgttcgaat aaaaggtttt cagttactat tcagtagcta ttgctttttt tgaatcgtgt
    12421 gtggtaacct aataaaaaag gaggtcggaa aaatgactgc atcgatgaaa ttacgtttcg
    12481 aacttttgaa taacaactaa ataaattcaa aagacatgta taaacaacaa tttcatggat
    12541 ggagtatgtc cattttttcg aacgacagta gaataggtga aagctatgac agatttggtg
    12601 atttagtcat agttatttcg ttcagagtag gaaaagatgt gatgcagttt ttttgcaaac
    12661 agatttttct gctctttttt agtatcgata attgttgttt tacatgaaat aggagtgtaa
    12721 aacatatgga aaatttagca gtaaatataa caaatctaca agtcagcttt ggcaaccagc
    12781 tagaactatc tattgattct cttcgtgtct atcagcaaga tcgtataggg atcataggag
    12841 aaaatggtgt cggtaaatcg actttgctca aactaatagc cggtgaactt tttcccgatc
    12901 atgggaaaat ccaaacagag atcaccttca actacctgcc tcaattaacc tatctcgctg
    12961 aagcaaagga cctaaatttg gaattagcca gtcatttcca gttaagactg gaagaaactt
    13021 cagagcggaa atggagcgga ggggaagaac gaaagatcga gttgatacgt cttctttctt
    13081 cttatgaaca agggatgctt ctagacgagc caacaaccca tctagataga aaaagtattg
    13141 atcgactgat tgaagagctt cgttattatt atggtacgct ggtttttgtt agtcatgatc
    13201 gctattttct agatgagcta gcatcgaaaa tctgggaagt aaaagacgga gaaatccgag
    13261 agttttcggg gaattatagt gcctatctca ctcaaaagga attggagaaa aagactcagc
    13321 tacgagaagc agagtcgatc atgaaagaga aaaaacgatt ggaaaaatcg atccaagaaa
    13381 agaaaaaaca agcggaaaag ttggaaaaag tgtccagtaa aaagaaaaag caacaaatca
    13441 gaccggatcg gttgtcttcc tctaaacaaa aagacagtgt acaaaaagcc atccaaaaga
    13501 atgcgaaaac attagagaga agactccaaa aaataggaga aacaaccaag ccgcagcaga
    13561 tgaaacaaat ccgttttcca gtaccaaaat ctcttgaact ccacagccgc tatcccatca
    13621 tgggacaaaa tgtccaattg gaaagaagtg ggagaacatt actggtaaat ggtgattttc
    13681 agttttcttt aggtaaaaaa atcgcgattg tcggtgaaaa tggttcaggt aagacaacct
    13741 tattagaaca tatccgcaaa caaggagaag gaatccttct ctctccgaaa gtaagctttc
    13801 aagtatatca gcaaaagggt tatcaaatga catctgaaga atccatcatt cgttttgtca
    13861 tgagacaaac agagttttca gaatcgcttg tccgtagttt gctgaatcac ttagggtttg
    13921 ctcaggaaac tttgacgaaa ccgttatgta cattaagtgg gggagaagcg acccgtctga
    13981 cgattgcttt gctttttact aagccaagta atgtgttgct gttagatgaa ccgactaatt
    14041 ttattgatat ggcaacgatc gaagctttag agaagctaat gcaaatatat ccgggaacga
    14101 ttttgtttac ttctcatgat tcttactttg tcgagcgtac ggctgatgaa gtttatgaaa
    14161 taaaagggca gaaaataaaa aaagtactta cgagaaattt ttaaatgtgc tacgatgatt
    14221 ttcgtgacaa atttaaagga gtggtacaga ttgcctacaa ataaaaaaga aggaataatt
    14281 tttacaacaa tgatgtgttt tttgatggtc ttggggatga gcgcgtataa tttatggctg
    14341 catcaagatc ttcatttatc aagtttgttg attggtctag tgcctggatt cgtggtggct
    14401 ttcattttgg atgtcttcat catcggtgtg ctggcgaaaa aaattgcctt taaactacca
    14461 gtaaatccag aaagcaaggt ccaaatgatc ttaactattt catgcttgat ggttttagga
    14521 atggtgacat gtatgtcttt attcggtgtg atcatggaac aaggaatacc tgatcaatta
    14581 ttctctgctt atatgaatgc ttggaaaatg aatgtgattg ccgctttacc gttgcagttg
    14641 atcatcgttg gcccgctttc aagaagtgtg ctaaaagcaa ttcaaagtaa tgaatgatgg
    14701 aacactgtta tttgaaaaaa ggccttggca tgctttttgt catagtctct tgaatgcagt
    14761 tctagaaaaa tagtgatccg aacgataggt tttggcctgt cgttcggatc gctttttctt
    14821 ttccaactgt attgctcttt tattgaagat aatttgctct tcaatagata tttctagaaa
    14881 ggttctgttt atcccttact caaaaaactg ctgcatttgt tctcttactt gctgacacca
    14941 ttggagttcc tgctgacaaa gcataattct gcgctggatc acaacataac gtccaaattc
    15001 ttgtttcttg tctagcgaga ggtcattcaa ttttttttga tttttttgca tgattttgtt
    15061 cagctgttgt tctctagtga atagcagtcc agtagctgtt gttttatcga gcgtcgaaaa
    15121 agcatagatt tttgctagaa attcatcttt ttgcgtagga gcgggagttt cctctttgat
    15181 ccattcctct acaagagcac gtccttcatc agtcaagtgg tagatctttt tttgagagtg
    15241 ctcgtctttg tccaaaacgg tcacataacc ctgctggtct aacttggcaa gcgttgtata
    15301 gatctgactg tgatgggctt cccaaaaaat tgtgatcagc tgcttcaatt catacccaga
    15361 acgtggtttg gataaaagca cgcataataa tatataggct aaagtattca taaaaatcct
    15421 acctctcgtc ttattttctt tattatatca cagtaaagtt tccacgtttt acatgtgcat
    15481 atttacatgt aaaataaatc atgtatgatg ctaatagaga gaaagggatg gaaatattgg
    15541 agaatcaaat agatatacaa gaacaaacaa atgaagaaac aaaggggaaa agttcagcgc
    15601 tagttgtagc agctacctgt atgatcgctt ttatgggagt gggtctagta gacccaatct
    15661 taaaaacgat tgctgcacag ttaaacgcta cgccagctga aacgaccctg ttatttacta
    15721 gttacatgtt agtcactggt gtggtgatgc tatttacagg tttcttatct agtcggatcg
    15781 gtttgaaaaa aacattgatg acaggattgt ttatcatcgt tgtattcgct ggtcttggcg
    15841 gattatctgg gaatatcgga atgctgattg ggttacgtgc cggctggggt gtcgggaatg
    15901 ctttatttgt ctctactgct ttagcaacga tcgtcagtat tttagttggt aacacagaaa
    15961 aagcaatcat gatgtatgaa gcagcacttg gctgcggaat ggctgttggc cctctagtcg
    16021 gtggggtctt gggcagtggt tcatggcgtt atccattttt tggggtagca tttttgatgt
    16081 tttgcggttt tatagcccta gcggtacttt tacctgaaac tgagaaacca aagagaaaag
    16141 taggcctttg ggaaggtgtc aaagcgttaa gcaatcataa acttcgttca gttggactaa
    16201 tcgcattgtt atataatttc ggattcttta ctttacttgc gtatgcgcca tttttattga
    16261 ttggctattc tgaattagaa gtcggttttg tattttttgg ctggggtgtg cttctggcta
    16321 ttgcttcgat tttcgttgca ccggctcttg agcggaagtt tacgacttat cggacaattt
    16381 tagcagcatt tgtcttattc attatttgtt tgctgttatt aggagctgga acttctatgc
    16441 cagtccttgt accgatcagc attgtgttag caggattttt ccaaggaatt atcaatacac
    16501 tgttgacgac gattgctatg gaaataccag gtctgcaacg aaacgttgct tcgtccagct
    16561 atagttttgt ccgctttttc ggtggagctt tagcaccatt tattgcaggt gtgattggtg
    16621 aacatattgg tgaaagctat gcgttttatt ttgcaggtgc cattgttctt atcagtgtat
    16681 gttgtatcat ttatcaccgt aattattttg ctacaaatga agaagaataa gaaatcagag
    16741 gttgtgaaaa agctgtcctg catcaagtca taagaa
//
LOCUS       DAFLWQ010000298        16297 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.guided.066, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000298 DAFLWQ010000000
VERSION     DAFLWQ010000298.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16297
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.guided.066"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            complement(34..1374)
                     /locus_tag="L1V16_003254"
     CDS             complement(34..1374)
                     /locus_tag="L1V16_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1277488.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            1643..2539
                     /locus_tag="L1V16_003255"
     CDS             1643..2539
                     /locus_tag="L1V16_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBN1277489.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(2689..3630)
                     /locus_tag="L1V16_003256"
     CDS             complement(2689..3630)
                     /locus_tag="L1V16_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBN1277490.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            3756..4877
                     /locus_tag="L1V16_003257"
     CDS             3756..4877
                     /locus_tag="L1V16_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBN1277491.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5135..6637
                     /gene="eat(A)"
                     /locus_tag="L1V16_003258"
     CDS             5135..6637
                     /gene="eat(A)"
                     /locus_tag="L1V16_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBN1277492.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            6665..7231
                     /locus_tag="L1V16_003259"
     CDS             6665..7231
                     /locus_tag="L1V16_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBN1277493.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            7442..8503
                     /locus_tag="L1V16_003260"
     CDS             7442..8503
                     /locus_tag="L1V16_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBN1277494.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            8506..9402
                     /gene="murQ"
                     /locus_tag="L1V16_003261"
     CDS             8506..9402
                     /gene="murQ"
                     /locus_tag="L1V16_003261"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBN1277495.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            9416..11398
                     /locus_tag="L1V16_003262"
     CDS             9416..11398
                     /locus_tag="L1V16_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1277496.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(11463..11909)
                     /gene="nrdI"
                     /locus_tag="L1V16_003263"
     CDS             complement(11463..11909)
                     /gene="nrdI"
                     /locus_tag="L1V16_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBN1277497.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            12120..13544
                     /locus_tag="L1V16_003264"
     CDS             12120..13544
                     /locus_tag="L1V16_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1277498.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(13725..14498)
                     /locus_tag="L1V16_003265"
     CDS             complement(13725..14498)
                     /locus_tag="L1V16_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBN1277499.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(14495..15400)
                     /locus_tag="L1V16_003266"
     CDS             complement(14495..15400)
                     /locus_tag="L1V16_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1277500.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(15554..15874)
                     /locus_tag="L1V16_003267"
     CDS             complement(15554..15874)
                     /locus_tag="L1V16_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBN1277501.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
BASE COUNT         5306 a         2935 c         3370 g         4686 t
ORIGIN      
        1 tccacataaa taaaataaaa ttttctatcg atttcattca ttcgtcaata cgaacgcatc
       61 attctttttt tgataactga aataaatgaa caggtaaagc aggccagtca atacagttac
      121 cccaatggag ttcgtgaaca ggataccaag gaaaatcaat cctaagacag ctaatgcaaa
      181 aaagctgatt cctttatccc ataatgttcc ttttcttagt gccagtacaa aggatgccgc
      241 actgataatg atccagatca ataatactgt atacgaaagg gaacctgcca gatagccaaa
      301 taatttgtca ccgacaaaat aagaaagagc tacaccaaga taaagaacac tggtacaaaa
      361 taaaacagca cgttgcggta cttgatgctt gtttaaaaca gctagttttc tagaggaacc
      421 ttttcgatcc ttcaaacgga agaacaaaat tcttgaagat gcatacacac ccgaattgat
      481 agatgagaac aaagcaagga caatcacaaa attgacgata tccgctgcaa atgggatatt
      541 cattttttca aataccatca caaaaggact gacattcgtg cctgctaaag tattccaagg
      601 aaaaagaatc aaaagcaaaa acaaaggaat gatgtaaaag gaaatgattc ttcccatgac
      661 acctttgatt gctttaggaa tcgcacgttt aggatcatct gcttcgctta ccgtgatagc
      721 aatcagttca gaaccgccgt aagaatagat aactacaagc aaagaactga tgattccctt
      781 cataccatga ggagtaaacc caccatggtc agtcaattgc tgaagggtag ggaaaacgcc
      841 tgtgcccaac atttgctgac cgacaagata agtagcaaaa atgatcagta agataatgac
      901 actgatttta gcaaaagcca gccaatattc tgtttctgcg aataaccgta ccgaataaag
      961 attgatgatc gtagttaaaa cagccaacat aaaaacaaat acccaggctg gaatgtgcgg
     1021 gaaccacaac tgcaaaaagg aagcagctgc aacagcttca gcgatgatat tgataatcca
     1081 catagaccag tagacccaat cagtaaaatc agcagaatga gcacctagat aagggcgtat
     1141 caaaccagat aatccgtgat gcgtgtcgcc accgcttaaa acgatttttc ccagaccttt
     1201 catcacgata tataaaatca gcccaccaat caaaaaagca atcaatacag aagggccggc
     1261 gatcccaatc gcttcgccac ttcctttaaa tagacctgca ccgattgctc cacctaaagc
     1321 taacatggtg atatgtctgg agctaagttg ttttttcaat tttttatctt ccataaatga
     1381 cctctttctt ttaaattcac aatcaaaatt tatattaaga ataaatagca atatttaaca
     1441 atgactaatg ataaaaaatt ttcagacaat tacaactatt cagaaaactt ttaggcgaat
     1501 tttaatagaa gaatgattta tttcatcata ttttcataca aatgttaaat tttcatacaa
     1561 atataggaaa cgttttactg gctttttact atttaaacag gctatcatag gaaaaagtga
     1621 cagagaaagt gaggcggaaa agatgaacaa aaatgacgta ctgctagttg caaaaaataa
     1681 atcactttat tttttgcctt ccatccgctc tttagatgtt tggtccggaa aagatttact
     1741 acagtcggaa ttcattaaat cagctagaca acagttggca aattatcagc tgatcgtttt
     1801 tttagattat ggatttgata tggagatggc tcgacgcgtg cgcccattta ccaatgcaaa
     1861 aattgtgtta tttttttgga atcacttcaa agcagaacac gaggcgatgc tgaagcaggc
     1921 acaagatgaa ccggcaatcg atgagattta tcattttgat tttttggaag caaaagaact
     1981 tgggctgaaa cataatagtt cattttattc gaaacatatg aatttttctt ctagcgaacc
     2041 aaagacggat ctattttttg gtgcaacgaa taatgggaga aaagaacgag cagaaagcta
     2101 taagcaggaa tttataaaaa gagatgttac gaccaactat ttcattcttc cacatcgagg
     2161 gaatgaacaa cctggatatc ttacttatga agagtacctg aaaaaaacag gggaatcgcg
     2221 cgggattctg gaactgttgc gggagggtca gcaaggagtg actttgcgga catttgaatc
     2281 catgtatttt caaaagaaac tagtgacgga taatcaagcg attgctcatt atcattttta
     2341 tcgtcctgaa aatatttttt tgcttcgaga acgtgattta gatgaattac cggaatttct
     2401 gcatacacca tttaagccaa tcctatcaga gctattggaa ttttatgatg cagaaaattg
     2461 ggcaaaacga tttatcacta acgattccac tatttatgag caatacgaat atgacctctc
     2521 ctctgttgaa aacaaataaa aaacctacat tttgaagaga ttatgtactg aaacaaacaa
     2581 gcacaattct tatggcatca tgagagttgt gttttctttt tgatctttta ttgggcttaa
     2641 aaaaagagaa ccagctgctg attcagctga ttctcatcag agagcctttt attctgcgcc
     2701 aaggattcct tcttttgcat ggactaattg ggtcaaaaag gcacaatatg gtgtagcaat
     2761 atcatatttt tgtccttttc gccaaatggc accattgatg tagtcgattt cagtcaaacg
     2821 atggtttttg atcaggtctt ggtacataga tgggtaatgc aacccgatgt tgtcaggatc
     2881 ataagtagaa gcaatatgtt ggtacacttc ttcttgatct agtatgattc cttcttttgc
     2941 tgcgatagaa gcaaattcag atacgattgt tcgaaccatg ctctctgccg ctttttgcgc
     3001 gcctagttca gcaatattac aatccaaaat cgtgcataaa ccattcaatg ttccatttac
     3061 acaagctttt cgccaaatgg aataacgaac gttatggcta tagatcggat ttaaatttgc
     3121 ttcttgaaag acttctacaa ctttttttgt aaatgcttcg ccttctggtt ccaagttctc
     3181 tagttcgatt tctccatcac ctaacaatgt gacttttccg ggaccagcta gaccagctgt
     3241 ccacatcgtg atcccaaata agatattttt ctttggcaca tatttttcca gtacatcttc
     3301 atgacctaat ccatttagta aacacaaaac ataagtattg tcagtaataa tggattggat
     3361 cgaacaaaac atatcatcta attgattggc ttttgttaat gctacgatca agtccacgtg
     3421 ttcgttgctt tcgatgattt cttctggtga atagattggc agttttgcga ccacttcttt
     3481 accgttaaag tcagcaatca acccatttgt acgaatggct tcaatgtgag caggccaacg
     3541 atcgatcaag aggacctcat ttccgctttg atgtagcatc aatccgattc ggctgcccat
     3601 tgctccggcc ccagctattg cgattttcat gttttttctc tcctttattc aatgagttcc
     3661 cttttagtat atagaaaaat ggaagaaaat agcattgttt tgtttgaaaa aaatgaaaaa
     3721 aagtgtctta cttaagaaga aagtgaggga tacagatgga tattttggcg gcaattgatt
     3781 catttaaagg aagtgcttct tcatttgaac taaatcaggc agttctaaat ggctgggaag
     3841 atcgtaaagg aagaaaaatc aatgtgccga ttgcagatgg cggagaaaat actgcagaag
     3901 caatctatta cgcgctcagg ggaacatggc gtaccattga tgggatggat ctcttattcc
     3961 gtcagcgaaa aatcagctat ttattgacaa cttggcaagg aaaaaacacc gcagtcatcg
     4021 aatctgcaca agcattgggg ttagatctac ttgataaacc aacggatcaa actatccgac
     4081 ttgcttccag ttatgcctta ggagaactta ttaaagatgc actgcttcaa gaagtagaac
     4141 aaattattgt cactttagga ggaagcgggt gtagcgatgg tggtctagga ttactccaat
     4201 ccttgggtgc ttctttagaa gggtacacag aaggaaatcc tttattatct actaaaaaac
     4261 ttcattttga tcgaagaaac gttcttgttt ctaaagtaaa attgattatc gctgcagatg
     4321 ttaccaatcc atatacaggt caacaaggag ctgcttggca atttggaaga caaaaaggag
     4381 gaatagatac gacgctagct ttcttagata aacaagcagg aaagattgct cagcaaataa
     4441 aagatttctg ggaggtggat ttagatgata ttccaggaag tggagcagca ggcggtattg
     4501 gtggagccct ttttttgttg ggagcgaaga tggtttctgg tttcgattta gtcagccaaa
     4561 tcactggatt ggaaaaaaag atcgaacaag cagatgtcat cattacagga gaagggcgga
     4621 tcgatcagca aacgatccac ggaaaagttc catacggtgt agcagtgctt gcaaaaaaat
     4681 atcgaaaacc aataatcgct atttgcggaa gtagagacca agagctagaa ggactttctg
     4741 attttctccc aattgtctta agtattcatt tgggtccaat aggtttagaa gaagcaatgg
     4801 aacacaggca aacattagaa aaaacaaaaa tcttaggaca gacacttagc agatttttca
     4861 ccatcctccc gaagtagttg acaaaatcat tttctttatg ctatcgtaat ttcaaatata
     4921 ggacaaagtg agggatccgt gcattgaaaa attaagtcga ttgatgaaag ctgcattcag
     4981 actgtacctt gtggagacaa ggaagcagtg tgcagatttt cgggattggc ttggtttttt
     5041 cgatgtatgg gtctttttgt gtgtatccaa cccttgcatc ctctttagcc agttctgaaa
     5101 ataggactgg tcttttttta cgaggtgatg gaaaatgtct aaaatcgaaa taaaaaatct
     5161 gacattcggc tacgacagcc aaggcacatt attatttgaa caagcaaatc taaattttga
     5221 cacacaatgg aaactaggac ttatcggacg aaacggtcga ggaaagacaa ctttactgaa
     5281 tattctacaa aacaaactac cttatcaagg gcaagtaatc catcagcaag aatttgccta
     5341 tttcccgcaa cagacaaaag ataaagaacg tttaacctat tacgtgttaa atgatattac
     5401 ggattttgag atatgggaaa tcgaaagaga gctccaattg atgcaaacag atcctgaaat
     5461 cttatggaga gaattcagca cactatcggg gggagagaag acaaaagtcc tactggcact
     5521 tttatttgtg gatgacactc atttcccgtt aatcgatgaa ccaacgaatc atttggatat
     5581 ctctggtaga aaacaagtag cggcttattt gaaaaagaaa aaacaaggct tcatcgtggt
     5641 cagccatgac cggggattta tcgatgaagt agtggaccat gttttagcaa tcgaaaaaag
     5701 tcaactggaa ctttatcaag ggaatttctc tatctatgaa gaacagaaaa aacttcgtga
     5761 tgaatttgaa atggctcaaa atgaaaaatt gaaaaaagaa gtcagtaggc taaagaaaac
     5821 agcagctgaa aaagccgaat ggtctcgttc ccgagaagga gataaaacaa agaaacaagt
     5881 cggattcatc gatactgaat ctagacgagt gaataaagga gcagtgggtg ctgatgctgc
     5941 acggacgatg aaacgatcca aagcaatcgt gaatcggatg gagacccaga tcagcgagaa
     6001 agaaaaacta ttaaaagata tcgaatatat cgattctttg acgatgaata gccaagcgtc
     6061 tcaccataag cgacttttaa gcgtagaaga tcttcaatta gggtatgaaa atctgttatt
     6121 cgagccaatt cattttacaa tcgagcctca tcagcgggtg gcgatttcag gtcctaacgg
     6181 tgcaggaaag tcatccatta tccattatct tctgggggca ttcaacggca aggttatagg
     6241 agaaaaatac cagccaaaac atctgagcat tagttatgca agccaaaatt atgaagacaa
     6301 tcgaggaacg ttggcggaat ttgcagagaa aaaccaagta gactaccaag catttttgaa
     6361 caacctccga aagcttggga tggaaagaga tgtttttcat aacaagatcg agcagatgag
     6421 tatgggccaa cggaaaaaag tggaattggc taaatcttta tcacagccag ctgaactata
     6481 tacatgggat gaaccattga attatttgga tgtcttcaat caagaacaat tagaacaact
     6541 gatcttgaac gtgaaacctg ccatgttact agtggaacat gatcaaacct tcctggataa
     6601 agtatctact gagattattt ctcttgagag aatctaaccc ttgtaatctc aagaacaaca
     6661 aggtatggtt aaggggaact ttgccaacga aggagagaat cacatgcttt atgtaacgag
     6721 acacggagaa acaacttgga acgcacaagg attagtttgc ggacgggcag atgtgccgct
     6781 gactgaaaaa ggacagatgc aggcacagaa actagcagaa aaggtagtag atttgcctgt
     6841 tccaatcacg aaaatcatcc attcccctct tcaacgagca agagatacag cacaagcagt
     6901 tgctgatcgt ctcagcttgc cgctgaccgt tgatgaacga ttggtagaaa tggattttgg
     6961 ggattatgat ggactgccaa gcaaagatga gaactttcaa aaagcacgtt tagcgttcgc
     7021 tgtacgattc ccaaatgggg agtcagtctt agatgtgtat gcacggatcg ttcctttatt
     7081 gaaagaatgc atcgaagacg aagaaaatgt ctatctgtta gtttgccata atgccttgat
     7141 aagagtgatc aatgcttatt ttcatccgat gcctaatgag gggttcttta cattcatggt
     7201 agataataca gaattggttt cttatgagta attatgtttt tgtgttattt aaataaaata
     7261 tttcaaggca ctgcttttgc ttagcagtgc cttttttagg ttatgacaat tcttttgata
     7321 atataaactc aacctttaga aatgaaattt aattatttta ataaaagtat tgaaattttg
     7381 tttctttaga tatatactct agtcatagaa atgaagacgg atacagaaaa agagggataa
     7441 tatgtttggc ttttcaatat ttatgaacga ttctttgtca gaagagaaga aacagtatat
     7501 ccgccaaatg gcatccaatg gctttgtcgg tattttcact tccatgcata taccagaaga
     7561 tgatgtttcg gcatatcaaa agcgattgat cgaactagga agcgaagcga aaaagaataa
     7621 actagaattg atggtcgata tttcaggaga ggcattggaa cgagcgggtt tttcattaga
     7681 agatctaacg cctttgaaag caattggtgt aacaggttta agaatggatt atcatatttc
     7741 caatcagcag attgccgact ggtcacatca attgaaaatc agtttgaatg ctagcacgat
     7801 cacgcctaaa gatatcgatg aattgaaaga agcagaagct gatttctcac agattgaagc
     7861 ttggcataat tattatccac gtcccgaaac agggctggac aaagaatggt atcagaaaaa
     7921 aaatcaatgg ctcaaaattc aaggtctcct tgtccaaggt tttgtaccag gagatacaga
     7981 gttgagaggc ccactatatc aaggattgcc aactttggaa gaacatcgag ggatccatcc
     8041 tcttgcaggc gctctagatc tattagcaag taacacggat attgtttaca tcggagatgc
     8101 aggtctgtca gaaaacgttc aggagcaatt tgcttctttc caaaaagaac agacagtctt
     8161 gctccatacg gaacctgtag atgaagaatt ttacgaatat atattaggga agcatacgaa
     8221 tcggcaagac gatgcaagag atgtcatacg aagcgtagat gcacgttttc gagagattcc
     8281 gcctatccca gcaagaaata cagctacgcg tatgaaaggg tctattactt tagataacga
     8341 aaagtatttg cgctatatgg gtgagatcca attaaccaaa tatgatttgc cagcggatga
     8401 aaaagtgaat gtagtagcta aagttatcaa agaagagcta ccattgatca accaaatcaa
     8461 agctggtatg aactatcaat ttataagaaa agaaggaaga taaaaatgag caaaatcaat
     8521 ttagagaacc taacaacgga acgcagaaac caagaaactt ttggattaga tgagatgagt
     8581 atttctcaag ccgttcaact aatgaacaaa gaagatcaga aagtggccgc tgcggttgaa
     8641 aaagaactga caagtatcga accagtgatt gctaacacga ttgagtcctt taaaaaaggt
     8701 ggacgtctga tttatatggg agccggaaca agtggaagac taggtgtgtt agatgctgct
     8761 gaatgcgtac cgacattcgg tgtagaaccg gaaatggtca taggtctaat tgctggtgga
     8821 gaagaagcaa tgactgtagc tgtcgaaggg gccgaagatt cttatgagct agggcaagaa
     8881 gatctaatca agctgaattt gacaaaaaat gatatagtta ttggtatcgc agctagcggt
     8941 cgtacaccat atgtgatcgg tggattagat tacgcaaaat cgatcggtgc tgtcacagga
     9001 acgatttctt gcaataaaca agccgaaatc agtaaacacg cggatttccc aatcgaagtc
     9061 gatgcaggtc cagaattttt gacaggctct actcgattga agtcaggaac agcacaaaaa
     9121 cttatcttga atatgatttc tactatcagt atgattggta taggtaaagt attcaataac
     9181 ttgatggtcg atgtcaaacc aacaaatgaa aaactaatcg aacgctcaaa acgaatcatc
     9241 atgcaagcga cagaagctga ttacgaaaca gctgaaaagt actttgaaga agcagatcaa
     9301 aatgttaagc tggctatcgt catgattttg acaaatagtg ataaagagga agctcaagca
     9361 aaattagctg aagcaaacgg atttgtaaaa gggaccttat gagggggaaa agaccatggc
     9421 aaaaaacgaa ctgactttgg aagaactggc aaaacaaatt tataaagggg caggcggcat
     9481 gggcaatgta gaaagcattg tccactgcat gactcgtgtg cgtatgaaga tcatcaatga
     9541 tgatcttgta aatgtctctg aattaaaagc gattccagga gtgcttggtg tagtagaaga
     9601 tgaacagctt caagtcatca tcggacctgg gaaagtgaac aaagtagcac agcaaatggt
     9661 tgatttggca ggcgtgaaat taggagaaaa actttcttct gtaagtacag ctacagcaaa
     9721 ttcatcagca tctggaaaag accgtgtaaa cgaacgggca caagaaatga aagcggcaca
     9781 aaaatcgaaa caaaaaccat ctaaaatcaa atcggtatta aaagacattt ctaatatctt
     9841 tgtgccaatg attcctgcat ttgtcggtac tgggatcgtg gcagggattg ccgcagtttt
     9901 agcaaactta gtcacagccg gaacacttga tgcagcaaca tggcaacaat atatcgatgt
     9961 gatgaacatc ttgaaaaacg ggatgtttag ctacctagtt atctatacag gtatcaatgc
    10021 tgcacaagtt tttggtgcaa caccaactct tggtggagtt atcggggccg ttgtgatgct
    10081 gacagggatg aatccggaag caccactgaa aaacttattt actggtgaag ctcttgcagc
    10141 tggacaaggt gggatcctag gtgtcatctt cgctgtttgg ctattgtcaa tcgttgagaa
    10201 aaaactgcat aaagtagtac ctgatgcggt agatatcatc gttacaccaa ctctttcatt
    10261 gattgccatc ggtctgattg aaattttctt catcatgcct ttagcaggtt tcatttctga
    10321 tggcatggtc ggtgggatca actgggtact tggcgttggt ggagcatttg ccggcttcgt
    10381 tctaggcaca ttattcttgc cgatggttat gttcggactg catcaaattt tgactccaat
    10441 ccatgtgcaa atgattgatg aaactggtcg tacgctattg cttccaattc ttgcgatggc
    10501 tggtgcagga caagtgggtg cagcattggc attatggatt cgctgcaaaa aagataaaga
    10561 attaacagaa atgatcaaag gagctttacc agtcgggatc ctaggaatcg gcgaaccatt
    10621 gatttacgga gtaacattac ctctaggacg cccatttatt actgcttgta tcggtggagg
    10681 tatcggcggg gcagtgatcg gaatgatcgg aaatgtcggg gctatcgcta ttggaccttc
    10741 aggagccgct ttgatcccat tgatctctga cggtaaatgg ttaggctaca tccttggatt
    10801 attggcagct tatgctggtg gcttcgttgc tacattcttc ttcggtattc ctaaagaccg
    10861 tttagaaaaa gaagaattag cgactgaaac agccacagta aatgaagtgc ctgaaaaagt
    10921 agtacctcaa acttcagctg aaagtgtgac tatcctctca tcagttgctg acggaacagt
    10981 tgtttcttta gataaagcaa gtgatccagt ttttgcacaa aagatgatgg gtgaaggcta
    11041 ctttgtagaa ccagaaaacg gacatatcta ttctccagtt actggggtag tcagctctgt
    11101 cttcccaacg aaacacgcta ttgggatcac aacgccaaat ggtttagaaa tcttgcttca
    11161 tatgggaatc aacacagttg acttaggcgg tacgccattt gatgtgaaag taacagaagg
    11221 gcagcaagtg acacctgata cgcttgtagc agaagctgac ttagaagcga tcaaagcagc
    11281 aggcaaagaa acatccatga tcgtcttggt aaccaatatg gatcgtgtaa aaaactttgt
    11341 cttggaaaaa acaggtaaag caaaagcaaa agcacctgtg atggatgtca aagcttaata
    11401 tgatagaaac aatagaaacg aaagaagaaa ctgaaatcta tttttcagct tcttcttttt
    11461 tattatttat tgttttctgc taaaatctga taaattcgtg tcacatcaga tggtgttccc
    11521 cgtaattcat aatctgccaa gaaaggaaag ccaaatgttt gtgcatattg tttggctgtt
    11581 agacaatact gattattgaa gtttttattt ccgctaccga ctacaccaag acaaagttta
    11641 tgattgtctt catgttccag atattcacgc atcgtttcgg tcaagatttc tgtatcaccg
    11701 ttatctaaac catttccgcc gtctaaataa gtaggaacga aagtaaaaaa tggttctgtt
    11761 tctttcgtaa aatcactatt ttcatggatt tcttttaaag taacttcagg attgacagga
    11821 tcttctgcat gcattttttc agcatattct gctagatgtt tggcaaaggc acgcgtattt
    11881 cctgaaatcg atatatataa aatgttcatg gatcatcctc caattctttc cttttagtat
    11941 agcatctttt ttaagttttt tggtggtgta atttggaaag ggactaggcg ctttgcttgt
    12001 ataatgagaa aaaagccggt agaattatat ttctattaaa gtttttatta attaagtaaa
    12061 aataaaaaag gtttgttata ctttttgata aaagcggttt tattttggag gatgcttaca
    12121 tggatacaga gcaacagaaa aaaggaattg gtttaattcc acttgctgcc ttagtaattg
    12181 gttcagcgat tggaggtggc gtatttggta ttatgacgga catctccgga tcggctggcg
    12241 gcccagctat tttcagttgg gtactcgtag gaacagcaat gttgatgctc tccttgtcga
    12301 tcaataatat caataaaaaa cgtccagatt taaaaggcgg gatctttagt tacgcagaag
    12361 aaggttttgg ccgtttcgct ggttttatca gcggttgggg ttactggctc acatgctggt
    12421 taggcaacgt agcttttgca acattgttga tgagcgcatt aggatatttc ttcccagtat
    12481 ttgaaggtgg gcaaaatctg gcatcgatcg tgatgagtac agtcttttta tggggatatg
    12541 catggctagt gaatcgggga gtcgaaaatg ctagtttcgt caatgctatc gtcacattct
    12601 gtaaattagt gccattattt ttatttattg tagtagctat cagcacgttt tcgatccaac
    12661 aattcattga taacttttct agcgacatta tattgaatgc gaatggacag ccgatcccgt
    12721 tttccagtca agtattgagt tgcatcatgg tgatgctttg ggtatttgtt ggtattgaag
    12781 gagcctctgt cgtaggttca cgagcaaaaa aacaatcaga tgttgggaaa gcaacgattc
    12841 tagggatatt cggcttgatt attatttacg tcttggtttc catgcttcca tatgggacaa
    12901 tgacgatgaa tcagctgcaa acgatcaagg cgcagcctgc tatgggctat gtgtttgaaa
    12961 tgatggttgg taaatgggga gcagtcgtga tcaacggcgg tttgatcatt tctttagttg
    13021 gtgtttggct ctcatggacg atcttaccga ttgaaacaat gggaaacatg gctgaagacg
    13081 gacttttgcc taaagcatgg ggaaaactca acaaaaatgg ggcaccaact tatgctatcg
    13141 tattgacgac gttatgtacg aatgtctttt tactttcatt attattcact gacagtgctt
    13201 ataactttgc ttacacactt ggtacagcag ctattttctt cacgtggctt ttcttaggat
    13261 tgtaccaaat gaaactttct tatcagcgga aagaatgggt ccaattttta gtagggcttt
    13321 tagcaagtgc ctttcaagta tgggctatgc tagtcgtagc ctttaatgaa gtaatgcttg
    13381 ttcttgttct tttcttgcca ggcatttatt tttacctcaa agcacgtaag gagcaaaacg
    13441 agcctgtaca acatatccac ttagataaga ttttacttat aggtgtgacg atggtcggag
    13501 tgattgcaat ggttttattt gccactggga tgcttcacgt atagaagtat aaaagaagta
    13561 taaagagagg ttgtgagcct gtcgtttatt caaaaacata ctaggaaagg agctgtgaca
    13621 caaatgttgt cacagctcct ttttcagaat aaacggtgtt taagagacag ccaatcggca
    13681 ataaggctga acgtctcttt cacagcctct tttttgatga gtcatcatac attttttcgc
    13741 ttaaatacga gatatcctaa tgctaagaac aaaacgatgt aagctaaatt accgaatagc
    13801 atttgattag tagaaagatg agtcaattgc ttcatgatct cttcgtttcc aatttggttt
    13861 tgcagattca acatactgat cggattccat ttgatccact cccatttttg gatgagtgca
    13921 ataaggatac cagatatgat tgacgaagca aaataaaaga cgattcctgc tgagatggat
    13981 gcgccggaac tattgataaa gcaagcaatc atcaacacta aacttaaaat cagccataaa
    14041 ccgatataac tacccaaagt ataagtgaac aagctttgga tcagtgtttg accagtagaa
    14101 accttctccg tgaaggaaat cgaagggaaa agaatcagtt tcatcaacac agtgacaata
    14161 atagctaaaa ggtataaata aacagaataa ataactaatg tgatccattt gcttactaat
    14221 atttctcctc gagaatactt tcgataaagg agatttttca atgtaccata ttgtgcttcc
    14281 atcgaaatga tcgtgcttgc agctgcaatc atgataaaga caatccaaga tgtggcacta
    14341 aaaagctgag cagtcatttc aactggatca atgatcgtcg tgtatttttt ggctagaagt
    14401 gctgttccta tgagcaaaac aactaataga acagataaaa cagcagttga ctttttcttg
    14461 atcaatttaa ataattcttg ttttacaagc aatgtcattt ttcttcttcc ccctttactg
    14521 aatccagaat ttccaataga gaagattcca aatcattcgt cagatgctgg acgtctgtca
    14581 catggatatt ttgtgcagac aatagctgga tcacggttcc taataattct tcgttttctt
    14641 ttaaaagctt gattttatca ggatcttcca aagtatatcc agcttctgtc aagatcgttc
    14701 gagcagctag atcatttgtt gtagagataa cgatgaaatc ttgcgctgtt tggttcaatt
    14761 cagccattgt acattgtttg atgatctttc cttgattgat caggatcagc tcatcgacca
    14821 ttttttcaag ctcgctgagt aagtgactgg agatcaagaa agaggtgccc tgagtagcca
    14881 agtcggtaat gatttttcgc acatctcttg ttgcttgtgg atccaaaccg ttcatcggct
    14941 catctaaaat aacgatagac ggatggttca gtaaggcaag agcaattccc aatttttgtt
    15001 tcattcccaa cgagtaggat ttcgcttttt tgtgaatgta cttttccatc ttgagctgat
    15061 tcacgatagt gtcgatagca gatacatcgt tggtttcaga gaataacttc agatgatcat
    15121 agcctgttaa gaatggatag atacccgggt attcgatcaa tgctcctact tgttccaacc
    15181 ctttatgact agagggagaa atctcatttt caccaataca gattgttcca tctgagtaat
    15241 ggatcagtcc taaaatagct ttcatgatcg ttgtttttcc agcgccatta ggacctacta
    15301 atccaacgat tttgccaggg gataagctaa aactgacatc gctgagggct tgtttgtgac
    15361 caaagttctt ggataattct tggaccgaaa gacttttcaa aaatattcac tccttttcta
    15421 tagatagtac aagcatacac ctgatgagtg gagaagtcgc taggtcattg gacttatttc
    15481 ttattttttc ataaaaaaat tgaatattaa ataaaaaggc ttattttttc tgatcagtac
    15541 ttattccaag tgtctagtgg ccgctagtaa tcttgatgcc aatgatactg atgagtagca
    15601 tccccacaaa gaaccaagtg gaaagattca gcttatcatg aaacaagacc acaccaatta
    15661 tgaccgaacc aactgcgcca atccctgtcc agataggata agagagactc atcggcaaac
    15721 ttttgattgc ctttgacaaa aagtaaaaac tagcaatcat gccaatcact gtgtaaaaag
    15781 aataattgat tttagaaaaa ccatcactcc atttcatcat cgttgaccag aatacttcca
    15841 aaattcctgc tatgattaat tccatccatg ccatacttac attcctcctt aactataaaa
    15901 aaatacacaa aaagaggaaa atcatccctt caaagaccta atggaatgat catcctcttt
    15961 atcctacccg gtggcagatt gtatatcttt ttctgtagta tagcacacct atccagatat
    16021 cggcaatctc atacttttta gtaaagtgta ccaagcactg acggatatat cgttagcgga
    16081 aaagaagatg aatgctttgc aatttcatag aaagaagttg ttatttatta atcatttaaa
    16141 aaaaacagta actagacctt atttctatat attatcgggc aataaattaa aaaaagcttt
    16201 accttacaat aagtaagata atttttgtga taaaaaaata acgaaaaata tttaaaaata
    16261 gtgtctattt cgtgagaaaa caactatatt ttttatg
//
LOCUS       DAFLWQ010000299         6026 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.guided.127, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000299 DAFLWQ010000000
VERSION     DAFLWQ010000299.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6026
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.guided.127"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            <1..2268
                     /locus_tag="L1V16_003268"
     CDS             <1..2268
                     /locus_tag="L1V16_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBN1277502.1"
                     /translation="IAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFYFG
                     ILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYFLI
                     AQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAAKE
                     ERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQLSF
                     VPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQDYE
                     LPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEVQP
                     AVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIEAQ
                     PNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRAKP
                     HEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAATGV
                     RNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMARA
                     AGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGDML
                     FLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQPQD
                     ELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKVFI
                     EQEETSETLPDDNDM"
     gene            2498..3565
                     /gene="rlmN"
                     /locus_tag="L1V16_003269"
     CDS             2498..3565
                     /gene="rlmN"
                     /locus_tag="L1V16_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBN1277503.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(3758..4861)
                     /locus_tag="L1V16_003270"
     CDS             complement(3758..4861)
                     /locus_tag="L1V16_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBN1277504.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            5413..5961
                     /gene="aac(6')"
                     /locus_tag="L1V16_003271"
     CDS             5413..5961
                     /gene="aac(6')"
                     /locus_tag="L1V16_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBN1277505.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2000 a         1046 c         1299 g         1681 t
ORIGIN      
        1 attgcaggaa atacttacca aatcctctgt cttttattag ccgtattagg attttggatt
       61 gtcattaaga atacagagtt ttcaattggt aaaaaccgac gctggtttgg cggcatactc
      121 ttttatttcg gtatcttatt attgttacat gcccatttat ttggcaaact ccatactggg
      181 gaaccaaata tcatggggac gacatgggat ttgttagcca gtgatataaa acaaagtcaa
      241 gtagacaata acgttggtgg tgggatgatt ggagcaatcc tttatcattt tacttacttc
      301 ttgattgcac agcctggaag ttatttagca gcagtgctat tactggcagg aggagcattc
      361 ctgttcagta atctggaagg ctatcagctg ttaaatggta tccaatcaat tggagaacga
      421 gtacaggaat tattggaagg tgatcctgcc aagcaagctc gaaagcaagc ggcaaaggaa
      481 gagagaatga aacagcgcgc agaagcgaaa gaagcaaggc gcttagctgc aaaagaagct
      541 gcagaaaaag aagctgcaga atatgagaag aaaaaagcgg tgagccagca aagggaaaat
      601 actgctgatg aatggcagga accagaaaat acagagccgg agcagctaag ttttgttcca
      661 atcgacagtt ttcaagaaaa tatccatcct gcgaatctag agaaaccagt accagataca
      721 ccaaaacaga ccaatacagc agaaggtttt tcagatgagt tgccagagga tgacggtacc
      781 tcattagaat ttgagattga agcagaacag gaaaatcaag actatgaatt accgacagtt
      841 gatttgcttg attctatacc aactgtggat caaagtgatg agtataaaaa aattgaaaaa
      901 aatatcggcg tattagaaca aactttccaa agtttcggtg tcgatgccaa ggtcgtcaaa
      961 gccagcttag gaccatccgt cacaaaattc gaagtccagc cggctgtagg ggtaaaagta
     1021 agtaaaattg tgaacttaac agatgatatc gcgcttgctt tagcggcgaa agatgtccgg
     1081 atggaagcac cgattccagg taaatcactg attggtattg aagtaccaaa tggaaagatc
     1141 agtatggttt cctttagaga aatcatcgaa gcacaaccaa accacccaga taaattacta
     1201 gaagtacctt taggacgtga tgtttctgga cgggtacaaa cggctgatct ttcgaagatg
     1261 cctcacttac tcgtggctgg ttcgactggt agtgggaagt cagtagcaat taatgggatt
     1321 atcacaagta tattaatgcg tgctaagccc catgaagtaa aactgatgat gatcgatccg
     1381 aaaatggttg aattgaatat gtacaacggc atacctcatc tgttgacgcc ggtcgtgacg
     1441 aaccctagaa aagcagcgca agccttacaa aaagtagtac aagaaatgga agaacgatat
     1501 gaaaaattcg cggcaaccgg agtaagaaat atttctggtt acaatgaatt tgttcaacag
     1561 aaaaacttgg aaaacggaac gaaacatcca accttaccat tcatcgtagt gatcgtagat
     1621 gaattagctg atttgatgat ggtagccagc aatgaagttg aagatgcgat tattcgttta
     1681 gcgcaaatgg ctcgggcagc ggggattcat atgatcctag ctactcaacg tccaagtgtg
     1741 gatgttatca caggaatcat caaagcaaat gtaccttcca gaatggcatt tgcggtatca
     1801 agcggtacag attctcggac gatcattgat tctaatgggg cagaaaagct cttagggcga
     1861 ggagatatgc tattcttgcc aatgggtgag aataaaccga tccgtgtgca aggagcattc
     1921 atttctgacc acgaagtaga acgggtcgtt caatttgtta cagatcagca agaagctcat
     1981 tatgaagaga aaatgatgcc gacagatgaa gttgaaacga caggtgctcc agaacagcca
     2041 caagatgagc tgtttgaaga agcaaaagca cttgtcgttg aaatgcaaac ggcaagtatt
     2101 tcccttctcc aaagaagatt tcggatcggt tacaaccgag cagcacgttt agtagatgaa
     2161 ctggaagctc atggagttgt tggcccgtca gaaggaagca agcctcggaa agtattcatt
     2221 gagcaggaag aaacatcaga aacgttgccg gacgataatg acatgtaaaa cttgtgtgat
     2281 gaagggttga aaaacgaata accaataaaa agacaaggca tgatgatacc aaaagaaaaa
     2341 atggtttttt tccatctttt ctaatacggt atgatgtctt gtctttttag tttttgtgag
     2401 attaaagttc tattcgattt atttgtgaag tattgcatta aggaaatgaa tcatgtatag
     2461 tatgtagcga aactttgaga aaaagaggga aaatactttg gaaaaacagt ccatttatgg
     2521 cttgacgaat gaagaattaa tcaattggtt tatagaaaac ggcgagaaaa aattccgagc
     2581 tgcccaagtt tgggaatggt tgtatcaaaa acgtgtaagt aatttcacag aaatgacgaa
     2641 tctatcgaaa caattgatcg aaaaattatc ggagcatttt atcatcaatc ctctaaaaca
     2701 gatggtcgtc caagaagctt cggatggtac agtaaaatat ttgtttgaac tccctgataa
     2761 aaacatgatt gagactgtac tgatgagaca agaatatggc ttgtcagttt gtgtgacgac
     2821 acaagtagga tgtaatatcg gctgtacgtt ttgtgcaagc gggctgctca aaaagaaccg
     2881 tgatctgact gctggagaaa ttgttgcaca gatcatgatg gtccaacatt attttgatga
     2941 gcgcaatctt ggcgaacgcg tttcacatgt cgttgtaatg gggatcggtg agccatttga
     3001 taattacgac aatgtaatgg actttttgca tatcatcaat gatgccaaag gattggcaat
     3061 tggtgctcgg cacattacag tttccactag tggattagca cacaaaatca aggaattcgc
     3121 taataacggc ttgcaagtca atctggctat ttccttgcac gcgccgaata atgaggtgcg
     3181 aacatcgatc atgcggatca accgaagttt cccaattgag aaattgatgg aagctgtgga
     3241 tgagtattta gagaaaacaa accgtcgaat cacgtttgaa tatatcatgt tgaatcaagt
     3301 aaatgataga ccagagcatg cgcaacaatt agcagatcta ttaaaagata agaaaaaatt
     3361 agcatatgtc aacttgattc catataatcc agtcagtgaa catgatcaat attctcgcag
     3421 tccaaaagct gatgtattga gattttatga tgtattgaag aaaaacggcg taaactgtgt
     3481 gatacgtaaa gaacatggta cagatattga tgcagcttgc ggacaattgc gaagcaagca
     3541 aatgaaaaaa acagttgcca aataatcgta tcctactcgt tttttcaatt accataaaag
     3601 gagcagtttt cttaattaag gaactgttca acttaaataa gagaaaagat tctatagcga
     3661 aagctataaa gctttttttg acaagaaaaa ccctcatcaa gcaaagaaat gtcctcaatt
     3721 tgatgacagc ctgcttgatg ggggttttag caattattta actgattttc ttatatcctt
     3781 gctggctttc ttgtgtagca tgataagttt ctacgtcaag aatggcctgt ttaaattttt
     3841 ctcgggtgat ttcataaggc acatgtttaa tatcatttgt tgccatggct ttatctaaga
     3901 ttgcttctaa atcggtcgtg acattgagat tcatgtcggt taacgatact ggaagttggt
     3961 tctttttcat aaacacatag attttatcaa acaaatcgaa ctgctgatcc atcatcaata
     4021 aggtcagtac accataactg acagatgctc cgtgaaggta tccctccatt ttttctagaa
     4081 cagtcgtacc gtaatagaat gagtgtgcca tagcagaatt atagttattg ttaactaaaa
     4141 cagaaaccaa tccggtagta acaatgatat ccgaaacgac ttgttcaatt gcatatgagg
     4201 gacgatcgtc ggcactatct ttcaatgctt gcgtaccata agtcaagaga cgatcaatgc
     4261 acatttttcc gatttggatt cctaatctat ccgtgtagcc tagatcatcg ccacgagcag
     4321 aaaaagtaga ttcgacttct ttggataaag catcgccaat acctgcccat aagtatttat
     4381 caggtgcttc ggcaataatt gctgtatcaa tgaaggtgtg tacaggtggt tttgaaggaa
     4441 agaagagtcc gtccattacg ccttcttcgt tatagatgac acataccgca gtgacgggcg
     4501 aacagttcga accaatagtg ggaaaggtga agactggttt agctagtttt tcaccaatga
     4561 cttttacagt atcgcaagca cggccaccac cgactgcaaa caggacgtct gctttttgga
     4621 cactttcatg ctggatcaac tgttcaatat ttccataagt tgaattaccc ccgtaccaga
     4681 gactggcgac aacctctatt tcctgtgtca aagctacttt tattttgttt tctgcctttg
     4741 aaagtgcagt cttccctcca atcagcacta cttttgtccc atattctttg acgattccat
     4801 ttgctttttc atacgcatct gttccaatgg tataatttgg taagaaaaca ctttgactca
     4861 tattcatttc cttctttctt cgttgaaacg ggttaaaatt ttaaagagtg atcgatctga
     4921 ctgcggctgt agatggagta gaggtgaacc taagacagga taagtgatga ataaggtggc
     4981 atgaacacct tgaaatcatc aataagtatc ctaaaaacga acaagtacaa aaacattgaa
     5041 aacgacaata atgaattttt gttcctctta gtatttctac cgattccctt tgcttttttg
     5101 taattatcta aaaattctaa aaattaagat tattatatga aaacaggttt tatttgtcaa
     5161 ttcataattg gtttttttta aagcaaaaga taatctatat catgatgaac aaacagagtt
     5221 ttttcctcca attgatggct ttcctgatct ttcctatttt gaataaagtg tttctgtata
     5281 attttttatt ttataagtaa gataaataat gaaagaatag agatactgat tggtagctaa
     5341 agatttttga gcgagaacat ttcgtttttt caaaaggact gttagaataa gcaagaacaa
     5401 gggggaagac gtatgataat cagtgaattt gaccgtaata atccagtatt gaaagatcag
     5461 ctttctgatt tactgagact gacttggccg gaagaatatg gagacagctc ggcagaagaa
     5521 gtagaagaaa tgatgaatcc agaacgaatc gcggtagcag cggtagacca agatgagtta
     5581 gtaggattta ttggtgcaat ccctcaatac ggtatcacag gttgggaatt gcatccatta
     5641 gttgtagaaa gctcccgacg aaagaaccaa ataggtactc gattagtcaa ttacttagaa
     5701 aaagaagtag cttccagagg aggaatcacg atttatttag gtacggatga tttagaccat
     5761 ggaacaacgt taagtcaaac ggacctgtat gagcatacat ttgataaagt ggcttccatc
     5821 cagaaccttc gtgaacatcc gtatgaattc tatgaaaaat taggttataa aatcgtaggt
     5881 gtcttaccaa atgcaaatgg ctgggacaaa ccggatattt ggatggcaaa aacgattatt
     5941 cctcgaccaa attctcaata ataaaaagag gttgtgacag aagtaatcag cttcaagaaa
     6001 taagaaggaa tttacgaaaa ttactt
//
LOCUS       DAFLWQ010000300         4499 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.guided.145, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000300 DAFLWQ010000000
VERSION     DAFLWQ010000300.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4499
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.guided.145"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            328..825
                     /gene="dfrG"
                     /locus_tag="L1V16_003272"
     CDS             328..825
                     /gene="dfrG"
                     /locus_tag="L1V16_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBN1277506.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(897..2849)
                     /locus_tag="L1V16_003273"
     CDS             complement(897..2849)
                     /locus_tag="L1V16_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBN1277507.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2856..3092)
                     /locus_tag="L1V16_003274"
     CDS             complement(2856..3092)
                     /locus_tag="L1V16_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277508.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            3494..3784
                     /locus_tag="L1V16_003275"
     CDS             3494..3784
                     /locus_tag="L1V16_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1277509.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT         1442 a          746 c          776 g         1535 t
ORIGIN      
        1 atctttctta acaagtaaac ctaaattagt aaagaagcaa cagtaatcta tactaagtag
       61 ttcagttttg gagtacaaaa tgacaaaatg tacttcaaaa tggactactt ttttcatttt
      121 aacttacata ccaaattaca tacaaaatga tttataaaat gcaattgaaa atgataattg
      181 aatgaaaatt tgtgattttg tggtattatg ataatataac ttatagaaaa aattgcttat
      241 tcaactaacg ggcaggataa tgagaaaagg ttttttgata gaaataagaa attagatggt
      301 aaattagtta aaaaggctgt gttataaatg aaagtttctt tgattgctgc gatggataag
      361 aatagagtga ttggcaaaga gaatgacatt ccttggagga ttcccaagga ctgggaatat
      421 gttaaaaata ctacaaaggg acatccgata atattaggta ggaagaacct tgaatcaatc
      481 ggaagagcct tacctgacag aagaaatatt attctgacga gagataaggg gtttaccttt
      541 aatggttgtg aaattgttca ttcaatagaa gatgtttttg agttatgtaa aaacgaagaa
      601 gaaattttta ttttcggagg agaacagatt tataatttgt ttttccctta tgttgagaaa
      661 atgtacatca caaaaataca tcatgaattc gaaggagata ctttttttcc agaagtgaat
      721 tatgaggaat ggaatgaggt atttgcccaa aaagggataa agaatgataa aaatccgtat
      781 aactactatt ttcatgtata tgaaagaaaa aacttattga gttaacgggt gcgttaattg
      841 aagaagaaca gtaaagataa agcacaagag cttgggatta ctccaagctc tttttgtcat
      901 ttgaaataaa ttatatcttt ccaatcaaat tgtttatctg taatccctaa tctttgagca
      961 ggtgtcaaaa cctttttatc cgctgattta aaagggcgac aaaagttgta gtaagttctt
     1021 agaattgtaa tcgcaaattg agcatacttc ggattgaagt tagcgtaaat atagctcttc
     1081 ttatcaccac gagctgttgt taatggtctt tcaagagatg atatataacg tcttatctgt
     1141 tgaataaagc tattggtcga atggtcatta acatttaata gcatctttgc gatttcgttt
     1201 ggttccagag cagataaatc cgttctacaa tcaactgaat aaaatccttt atccttagtg
     1261 gctaatggat gtttgatagg gttatcggca tatttgcgat atctttctcc atctttacta
     1321 atagcctctt cgtggaattg atgacttgtt agtaattcag ttagataatg agatgccaaa
     1381 gtccgtagaa actttgtttt gaatcctctg atatctcccc aatcgagcag ttctgctttt
     1441 gcttgtccga attcttttaa gcattgtttt ctgcttttcg tcttgttaac ttggcaaata
     1501 aaatgatgtg catcgctcaa ccttaattct ttcgtgaata ctctataaaa ggcgtttcta
     1561 atagagaagt catcatcact aatcattcgc cattcgtcgg cattaaccat ttgtttaatt
     1621 aaccaatagt gagcagttgt agtataagga gcatcaacat ttaaaccatc gacaaatcta
     1681 ctcctattag taattttccc taattcgtga agataagcat tcctattttc gctatcgtta
     1741 gcggatggtt cttgtggata ataagaccaa tctaacctat catttttacg actaaaagta
     1801 ttgagatggt cttctttgaa ttttcttgta tcttcattta attcatccat tgaaatattc
     1861 caatcatagg caacatcaga acggaacaca tatcttgata agacctcagc agatacaact
     1921 atatacgttt gcatattaag gtcttcaaac cccgtatatt tctttgaacc ttgtcctttc
     1981 ttacggacgt tatttaggta gtagtgcatc ttgtccgtat taagccacat ctcgttaaat
     2041 ttctttgttt gaaggggttg tgtctcatat cgttctaaaa actccaaaca acgcctatac
     2101 agccactcca gcttatgata gtaggttcca actccaattc ctaaaatatc acaagtacga
     2161 ctgactgaaa cccttccaac aaccatctta gcgaacattg gaagaatggt gttcttttgt
     2221 tggtgataag tagtggtttc ttctcttttt ggtagaacat tagtgaactt cttacacgcc
     2281 ttacattgat agcgttgaga tttgccccta cttttccccc ttttgtaaaa ttgcttcggc
     2341 tcattgaatg gggttgattc ttcttccgag cagccttctt tatgaaattg ataatctggc
     2401 tcaacatctt ggatgctatt gatttctata aggcgtttaa tttcttcaac aacagaccaa
     2461 ttagataaag gggttactgt acagttttgc gatacacctc tgccaatagg attgtcattg
     2521 cagtacatac ctttatgacc tttatctttg gaactaccag tcattttata tcgacttggt
     2581 ttccctttta catctttgaa tttgtgctgt tctttcccaa aattacaaca aaacggattg
     2641 atgcagtaat tatattgaat gggatattca gaaccgttcc atttaaaaga cgttggcaag
     2701 aacaacattt tgttatacct tgttgcaaat cgttttggag ttaataaatc atattgttta
     2761 gccctatctt ttaattcttc gtttgaaatc ggaattttaa catctacaat ttcatcttcc
     2821 ttcgtggcta atcttttaag cttggtcatt gtctatcaac ccactctatc tttgataccc
     2881 attttttcaa caatccgctt attacttcgc ttgttggcaa tccattcaat aaacttctta
     2941 tcgtctaaaa tgttcaataa gaattcatcc actgcttcgc tttcagtacg ctctgcatat
     3001 tcagcgtatt gcttaactat cacccttact tgctctgata tttcccaatc cacagactta
     3061 gcgttcttat tttttggctc aagaaattgc ataggaaaat gcaccccttt ttgcttagta
     3121 aattgtaacc attttaacac accaatttgc attcctacaa taattatttc acgttcgcat
     3181 ttttatatac attttaactt acattttgtg gtgtaaatta acaacaaacg ttgatttaac
     3241 aataaaaaac gagtatcaaa ttcagttgca atttgatact catttaggtt tacattttca
     3301 ctttttgtac tccaaaactg aactacttaa atctatactg ctgcctcttt tttttagtac
     3361 atgtccttca tcttcgcagg aagtgccaat atgattttaa gaaaggtaat agacaaaaag
     3421 tcaaaaagat aaaacagagt ttcttcttta caaagggaat gtatgttcgt ataatggtat
     3481 tgaggtgaag gttatggaga aaaaatatgg aacagtagat aagatccgta ctttgcaagt
     3541 tagtgccaga ccgttgatcc gtttcagttt aaatggggtc aattgtttga ttgcttccca
     3601 tagtttgaac ttcctagctg aagtagacga agggatgaag ttagtcgtta caggttatta
     3661 taataataga aagcaatttg ttgtgagatc ctatcatgtg ttagggaaac ccaaaattgt
     3721 ggtagaatat gagaaaagtc tatacccaag aaaaaaggtc cgacaagatg aaagaataaa
     3781 ctagaaaaca agcggctgag acaaaaatgt cctagccgct tgttttggaa agatggatgc
     3841 agacgatggg atttgaaccc acacgagcat acgctcacaa gaacctcaat ctatatataa
     3901 ctacatgtat ttaagtattt gtgatgaatc actaaacttt ccaaactcat ttgagggata
     3961 ttgcttaaag attgaacaga tcaattcgaa gccctattag tattcgctca atggggggat
     4021 cagaggccat aaaaagagac tagtcattac tagtctcagg tagtggaatt gtaggatttt
     4081 aaacgttcct ggagagtacc ggtatgtaac tcgaagaggt gattatcata gtcgtaaaag
     4141 taaattgaag aagcctcgcc tttcacacga gaacgtcctg gttcgacagt taaacctaac
     4201 atttggattt ttgagacaaa cgaatctata tcttgttcgt caattttaaa agcaatatga
     4261 ttgtatgtct ttggcagttt attcgacgaa ttctgcatta ctgcaatcca taggtcctta
     4321 actaagaaaa atttttctgg atataatgaa aatttttttg ttgactatcg tagatttctt
     4381 ttgcatcaaa taaggtattt aacaattaag tatttaaaag ataactttta agttatcttt
     4441 aagtaatgct taaagctatg ttatactcta ttaggaaata taagaaggag tataaaaat
//
LOCUS       DAFLWQ010000301         2946 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.guided.178, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000301 DAFLWQ010000000
VERSION     DAFLWQ010000301.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2946
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.guided.178"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            47..955
                     /locus_tag="L1V16_003276"
     CDS             47..955
                     /locus_tag="L1V16_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HBN1277510.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            952..1494
                     /gene="sat4"
                     /locus_tag="L1V16_003277"
     CDS             952..1494
                     /gene="sat4"
                     /locus_tag="L1V16_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HBN1277511.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            1587..2381
                     /locus_tag="L1V16_003278"
                     /note="aph(3')-IIIa"
     CDS             1587..2381
                     /locus_tag="L1V16_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HBN1277512.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            2657..>2946
                     /locus_tag="L1V16_003279"
     CDS             2657..>2946
                     /locus_tag="L1V16_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBN1277513.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIK"
BASE COUNT         1000 a          452 c          686 g          808 t
ORIGIN      
        1 aaaagaagat gtaataatat agaaaaaata aacgaggagt atgtaaatga gatcagaaaa
       61 agaaatgatg gatttagtac tttctttagc agaacaggat gaacgtattc gaattgtgac
      121 ccttgagggg tcacgcgcaa atattaatat acctaaagat gaatttcagg attatgatat
      181 tacatatttt gtaagtgata tagaaccgtt tatatctaat gatgactggc ttaatcaatt
      241 tgggaatata ataatgatgc aaaagccgga ggatatggaa ttattcccac ctgaagaaaa
      301 gggattttcc tatcttatgc tatttgatga ttacaataaa attgatctta ccttattgcc
      361 cttggaagag ttagataatt acctaaaggg cgataaatta ataaaggttc taattgataa
      421 agattgtaga attaaaaggg acatagttcc gactgatata gattatcatg taagaaagcc
      481 aagcgcaagg gagtatgatg attgctgcaa tgaattttgg aatgtaacac cttatgttat
      541 taaaggattg tgccgtaagg aaattttatt tgctattgat cattttaatc agattgttcg
      601 ccatgagctg ctgagaatga tatcatggaa ggtcggcatc gaaacaggct ttaaattaag
      661 tgtaggcaag aactataagt ttattgaaag gtatatatcc gaggatttgt gggagaaact
      721 tttgtccacc taccggatgg attcctatga aaacatatgg gaagcattat ttctatgcca
      781 tcaattgttc agggcggtat ccggtgaggt ggcggaaagg cttcattatg cctatccgga
      841 gtatgatagg aatataacaa aatataccag ggacatgtat aaaaaataca ctggtaaaac
      901 cggctgcctg gatagcacat atgccgctga tatagaagag aggcgggaac agtgattaca
      961 gaaatgaaag cagggcacct gaaagatatc gataaaccca gcgaaccatt tgaggtgata
     1021 ggtaagatta taccgaggta tgaaaacgag aattggacct ttacagaatt actctatgaa
     1081 gcgccatatt taaaaagcta ccaagacgaa gaggatgaag aggatgagga ggcagattgc
     1141 cttgaatata ttgacaatac tgataagata atatatcttt actaccaaga cgataaatgc
     1201 gtcggaaaag ttaaactgcg aaaaaattgg aaccggtacg cttatataga agatatcgcc
     1261 gtatgtaagg atttcagggg gcaaggcata ggcagcgcgc ttatcaatat atctatagaa
     1321 tgggcaaagc ataaaaactt gcatggacta atgcttgaaa cccaggacaa taaccttata
     1381 gcttgtaaat tctatcataa ttgtggtttc aaaatcggct ccgtcgatac tatgttatac
     1441 gccaactttg aaaacaactt tgaaaaagct gttttctggt atttaaggtt ttagaatgca
     1501 aggaacagtg aattggagtt cgtcttgtta taattagctt cttggggtat ctttaaatac
     1561 tgtagaaaag aggaaggaaa taataaatgg ctaaaatgag aatatcaccg gaattgaaaa
     1621 aactgatcga aaaataccgc tgcgtaaaag atacggaagg aatgtctcct gctaaggtat
     1681 ataagctggt gggagaaaat gaaaacctat atttaaaaat gacggacagc cggtataaag
     1741 ggaccaccta tgatgtggaa cgggaaaagg acatgatgct atggctggaa ggaaagctgc
     1801 ctgttccaaa ggtcctgcac tttgaacggc atgatggctg gagcaatctg ctcatgagtg
     1861 aggccgatgg cgtcctttgc tcggaagagt atgaagatga acaaagccct gaaaagatta
     1921 tcgagctgta tgcggagtgc atcaggctct ttcactccat cgacatatcg gattgtccct
     1981 atacgaatag cttagacagc cgcttagccg aattggatta cttactgaat aacgatctgg
     2041 ccgatgtgga ttgcgaaaac tgggaagaag acactccatt taaagatccg cgcgagctgt
     2101 atgatttttt aaagacggaa aagcccgaag aggaacttgt cttttcccac ggcgacctgg
     2161 gagacagcaa catctttgtg aaagatggca aagtaagtgg ctttattgat cttgggagaa
     2221 gcggcagggc ggacaagtgg tatgacattg ccttctgcgt ccggtcgatc agggaggata
     2281 tcggggaaga acagtatgtc gagctatttt ttgacttact ggggatcaag cctgattggg
     2341 agaaaataaa atattatatt ttactggatg aattgtttta gtacctagat ttagatgtct
     2401 aaaaagcttt aactacaagc tttttagaca tctaatcttt tctgaagtac atccgcaact
     2461 gtccatactc tgatgtttta tatcttttct aaaagttcgc tagatagagt tctatattag
     2521 agatgtaaag agttttggtg aagaggtttg tgagtatggc ttttataacc agggtgcaat
     2581 gagaagcact aacagcagct agcttaagaa cgcataggat atacttttta tggaagtcac
     2641 agaggaggaa taaaatttga acaggattaa cagagtaacc tctattctta ttcagctgca
     2701 atcaaaaaaa ataattcctg ccaaagaaat tgcacagcga tttaatataa gcttaaggac
     2761 agtttacaga gatatccgga cacttgaaga agccggaata ccaattggat ctgaggccgg
     2821 aaaaggatat tttcttgtag agggcttcct acttccgccg gtaatgttta cagcggcgga
     2881 agtgggtgca ttgattacag cagggaaatt tttaaattgc catggagatg aatcatttat
     2941 aaagga
//
LOCUS       DAFLWQ010000302         2771 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.guided.181, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000302 DAFLWQ010000000
VERSION     DAFLWQ010000302.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.guided.181"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            110..193
                     /locus_tag="L1V16_003280"
     CDS             110..193
                     /locus_tag="L1V16_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBN1277514.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            318..1055
                     /gene="erm(B)"
                     /locus_tag="L1V16_003281"
     CDS             318..1055
                     /gene="erm(B)"
                     /locus_tag="L1V16_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBN1277515.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1318..2181)
                     /locus_tag="L1V16_003282"
     CDS             complement(1318..2181)
                     /locus_tag="L1V16_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBN1277516.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2183..2455)
                     /locus_tag="L1V16_003283"
     CDS             complement(2183..2455)
                     /locus_tag="L1V16_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBN1277517.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2472..2681)
                     /locus_tag="L1V16_003284"
     CDS             complement(2472..2681)
                     /locus_tag="L1V16_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBN1277518.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
BASE COUNT          851 a          487 c          443 g          990 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccaaa attttgtata ataggaattg
       61 aagttaaatt agatgctaaa aatttgtaat taagaaggag ggattcgtca tgttggtatt
      121 ccaaatgcgt aatgtagata aaacatctac cgttttgaaa cagactaaaa acagtgatta
      181 cgcagataaa taaatacgtt agattaattc ctaccagtga ctaatcttat gactttttaa
      241 acagataact aaaattacaa acaaatcgtt taacttctgt atttatttat agatgtaatc
      301 acttcaggag tgattacatg aacaaaaata taaaatattc tcaaaacttt ttaacgagtg
      361 aaaaagtact caaccaaata ataaaacaat tgaatttaaa agaaaccgat accgtttacg
      421 aaattggaac aggtaaaggg catttaacga cgaaactggc taaaataagt aaacaggtaa
      481 cgtctattga attagacagt catctattca acttatcgtc agaaaaatta aaactgaaca
      541 ctcgtgtcac tttaattcac caagatattc tacagtttca attccctaac aaacagaggt
      601 ataaaattgt tgggaatatt ccttaccatt taagcacaca aattattaaa aaagtggttt
      661 ttgaaagcca tgcgtctgac atctatctga ttgttgaaga aggattctac aagcgtacct
      721 tggatattca ccgaacacta gggttgctct tgcacactca agtctcgatt cagcaattgc
      781 ttaagctgcc agcggaatgc tttcatccta aaccaaaagt aaacagtgtc ttaataaaac
      841 ttacccgcca taccacagat gttccagata aatattggaa gctatatacg tactttgttt
      901 caaaatgggt caatcgagaa tatcgtcaac tgtttactaa aaatcagttt catcaagcaa
      961 tgaaacacgc caaagtaaac aatttaagta ccgttactta tgagcaagta ttgtctattt
     1021 ttaatagtta tctattattt aacgggagga aataattcta tgagtcgctt ttgtaaattt
     1081 ggaaagttac acgttactaa agggaatgta gataaattat taggtatagg gcacctctaa
     1141 taactaccaa ttaattcacc tcaaaatgaa attagaaaaa aacagcgaaa tttttaaatc
     1201 tatttcttat cgatacaaat tcctcgtagg cgctcgggac cccaacatga ggaaatgttt
     1261 ttataaaaaa agagtagtta ccgttttttg gtaactactc ttttcctttt ttaaggttta
     1321 aatacctgga agtttaggtg ttttgggtat tggtggtgta ggtagctgca agctttccat
     1381 tttttgttga attgctttaa attcaggggt ttcttggtgt tgattttgaa ccattttttg
     1441 ctctattctc tccaaagtcg gttgaatttc tttccctgat actttacgat ttaattctct
     1501 ttctaaggtc tctttcggac taatggaagg cgtttctaag cttgaataga gtttcactcc
     1561 ttctctattg taaagcctta tatcgctaaa taagcccgtt ttatgaaggg tttctaaatt
     1621 ggtcggtaag tttttgacaa caatatcatg cgcttgtttt ggtgttgccc tagctgtcat
     1681 tggatcatct gcatacatgg tttcatatcg ttcaatcgtt cctaagtatg attcaatttt
     1741 cggtactgcc atgacgtata tttttgtttc ataaccttta gattgaagca ttgtggctgt
     1801 ttgaatggga acgtctgttg ttcgtcctgt tccttcaatc actaaattat agccttgatc
     1861 gcttaaacgg ctaataagtg cttctgtcat gcgattcgaa taaggggtaa cgtgttttac
     1921 tacgtctttt tcatagagtt tcactaattc gtcaaaattt gggtgctgtt gtttaaaggt
     1981 atcattatca atgacaataa cattcccttg tgtttcttca aaaattgctg atcgcaaact
     2041 ggttttccct gaccctggtt gcccaccaag taaaaaagcg gttggcgatt caaccgctag
     2101 tctattttta gttagtcgtt caacattctt ttctaaacga tcttcaaatt gcttttcggt
     2161 gaagtcagta atattcgcca tgttaagcca ctttctcttt attcaaaatt tgttttgaat
     2221 attgattcat tgaccgccaa tactcatgaa tagcttgtaa ttcttcaaat ggttgttgaa
     2281 ataaatcaac ttcttgtgcc acttctaatt gatttaaaag attcacttct agtaaacgag
     2341 tatttttagt atctagttca tgattcaaaa cataatttaa tacccgatta taaacacttg
     2401 ccgataactc attaatgatt tcaatttcaa atgttttttc atacgtaact gccatttcat
     2461 tttcactcct tttaaagttt gtcaggtaaa tatttccgta tatattcttc taaggcttga
     2521 tccataactt cttttacgtt tccgccattc tttgctgttt cgatttttat gatatggtgc
     2581 aagtcggcac gaacacgaac cgtcttatcc cccattatat ctttttttgc gctgattggc
     2641 gtatcatttc gttttgcttt ctgtgcgcct aaatttccca cgatcgctca cttctttcta
     2701 tttcttctta ctatttattt tatcatcacc tatcacaaat cacaagtgat ttgtgattaa
     2761 tcacttgtga t
//
LOCUS       DAFLWQ010000303         1781 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.guided.205, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000303 DAFLWQ010000000
VERSION     DAFLWQ010000303.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1781
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.guided.205"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            24..416
                     /locus_tag="L1V16_003285"
     CDS             24..416
                     /locus_tag="L1V16_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1277519.1"
                     /translation="MKLLFIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            417..>1781
                     /gene="aph(2'')-I"
                     /locus_tag="L1V16_003286"
     CDS             417..>1781
                     /gene="aph(2'')-I"
                     /locus_tag="L1V16_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APH(2'')-Ia/If/Ih family aminoglycoside
                     O-phosphotransferase"
                     /protein_id="HBN1277520.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVY"
BASE COUNT          731 a          136 c          303 g          611 t
ORIGIN      
        1 tatagttgaa gaatattatc ctattgaaac tattgtttat tgatgataat atggtttttg
       61 atattgataa tttaaaagga tttcttaatg ataccagttc atttgggttt atagctaaag
      121 aaaataataa aattatagga tttgcatatt gctatacact tttaagacct gatggaaaaa
      181 caatgtttta tttacactca ataggaatgt tacctaacta tcaagacaaa ggttatggtt
      241 caaaattatt atcttttatt aaggaatatt ctaaagagat tggttgttct gaaatgtttt
      301 taataactga taaaggtaat cctagagctt gccatgtata tgaaaaatta ggtggtaaaa
      361 atgattataa agatgaaata gtatatgtat atgattatga aaaaggtgat aaataaatga
      421 atatagttga aaatgaaata tgtataagaa ctttaataga tgatgatttt cctttgatgt
      481 taaaatggtt aactgatgaa agagtattag aattttatga tggtagagat aaaaaatata
      541 cattagaatc attaaaaaaa cattatacag agccttggga agatgaagtt tttagagtaa
      601 ttattgaata taacaatgtt cctattggat atggacaaat atataaaatg tatgatgagt
      661 tatatactga ttatcattat ccaaaaactg atgagatagt ctatggtatg gatcaattta
      721 taggagagcc aaattattgg agtaaaggaa ttggtacaag atatattaaa ttgatttttg
      781 aatttttgaa aaaagaaaga aatgctaatg cagttatttt agaccctcat aaaaataatc
      841 caagagcaat aagggcatac caaaaatctg gttttagaat tattgaagat ttgccagaac
      901 atgaattaca cgagggcaaa aaagaagatt gttatttaat ggaatataga tatgatgata
      961 atgccacaaa tgttaaggca atgaaatatt taattgagca ttactttgat aatttcaaag
     1021 tagatagtat tgaaataatc ggtagtggtt atgatagtgt ggcatattta gttaataatg
     1081 aatacatttt taaaacaaaa tttagtacta ataagaaaaa aggttatgca aaagaaaaag
     1141 caatatataa ttttttaaat acaaatttag aaactaatgt aaaaattcct aatattgaat
     1201 attcgtatat tagtgatgaa ttatctatac taggttataa agaaattaaa ggaacttttt
     1261 taacaccaga aatttattct actatgtcag aagaagaaca aaatttgtta aaacgagata
     1321 ttgccagttt tttaagacaa atgcacggtt tagattatac agatattagt gaatgtacta
     1381 ttgataataa acaaaatgta ttagaagagt atatattgtt gcgtgaaact atttataatg
     1441 atttaactga tatagaaaaa gattatatag aaagttttat ggaaagacta aatgcaacaa
     1501 cagtttttga gggtaaaaag tgtttatgcc ataatgattt tagttgtaat catctattgt
     1561 tagatggcaa taatagatta actggaataa ttgattttgg agattctgga attatagatg
     1621 aatattgtga ttttatatac ttacttgaag atagtgaaga agaaatagga acaaattttg
     1681 gagaagatat attaagaatg tatggaaata tagatattga gaaagcaaaa gaatatcaag
     1741 atatagttga agaatattat cctattgaaa ctattgttta t
//
LOCUS       DAFLWQ010000304         1310 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-45
            SAMN14852359-rid13729433.guided.225, whole genome shotgun sequence.
ACCESSION   DAFLWQ010000304 DAFLWQ010000000
VERSION     DAFLWQ010000304.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852359
            Sequence Read Archive: SRR11730509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222320.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222320.1
            Genome Coverage       :: 252x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 06:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,287
            CDSs (total)                      :: 3,225
            Genes (coding)                    :: 3,146
            CDSs (with protein)               :: 3,146
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 18 of 79
            Pseudo Genes (multiple problems)  :: 11 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852359-rid13729433.guided.225"
                     /isolate="VRE-ING-45"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2016"
     gene            228..1103
                     /locus_tag="L1V16_003287"
                     /note="aph(2'')-Ia"
     CDS             228..1103
                     /locus_tag="L1V16_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021424053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HBN1277521.1"
                     /translation="MKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTN
                     KKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTM
                     SEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEK
                     DYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDF
                     IYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEF
                     IENGRKEIYKRTYKD"
BASE COUNT          557 a          106 c          210 g          437 t
ORIGIN      
        1 gtacaagata tattaaattg atttttgaat ttttgaaaaa agaaagaaat gctaatgcag
       61 ttattttaga ccctcataaa aataatccaa gagcaataag ggcataccaa aaatctggtt
      121 ttagaattat tgaagatttg ccagaacatg aattacacga gggcaaaaaa gaagattgtt
      181 atttaatgga atatagatat gatgataatg ccacaaatgt taaggcaatg aaatatttaa
      241 ttgagcatta ctttgataat ttcaaagtag atagtattga aataatcggt agtggttatg
      301 atagtgtggc atatttagtt aataatgaat acatttttaa aacaaaattt agtactaata
      361 agaaaaaagg ttatgcaaaa gaaaaagcaa tatataattt tttaaataca aatttagaaa
      421 ctaatgtaaa aattcctaat attgaatatt cgtatattag tgatgaatta tctatactag
      481 gttataaaga aattaaagga acttttttaa caccagaaat ttattctact atgtcagaag
      541 aagaacaaaa tttgttaaaa cgagatattg ccagtttttt aagacaaatg cacggtttag
      601 attatacaga tattagtgaa tgtactattg ataataaaca aaatgtatta gaagagtata
      661 tattgttgcg tgaaactatt tataatgatt taactgatat agaaaaagat tatatagaaa
      721 gttttatgga aagactaaat gcaacaacag tttttgaggg taaaaagtgt ttatgccata
      781 atgattttag ttgtaatcat ctattgttag atggcaataa tagattaact ggaataattg
      841 attttggaga ttctggaatt atagatgaat attgtgattt tatatactta cttgaagata
      901 gtgaagaaga aataggaaca aattttggag aagatatatt aagaatgtat ggaaatatag
      961 atattgagaa agcaaaagaa tatcaagata tagttgaaga atattatcct attgaaacta
     1021 ttgtttatgg aattaaaaat attaaacagg aatttatcga aaatggtaga aaagaaattt
     1081 ataaaaggac ttataaagat tgattatata atatatgaaa agctattata aaagacatta
     1141 gtattaaata gtttaaaaaa atgaaaaata ataaaggaag tgagtcaatt ccagactcct
     1201 gtgtaaaatg ctatacaatg tttttaccat ttctacttat caaaattgat gtattttctt
     1261 gaagaataaa tccggttctg ttgcaaagtt ttaaatctac tatcaaataa
//
